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Sample records for cell slick rock

  1. Environmental assessment of remedial action at the Slick Rock uranium mill tailings sites Slick Rock, Colorado

    International Nuclear Information System (INIS)

    The Uranium Mill Tailings Radiation Control Act of 1978 (UMTRCA) authorized the US Department of Energy (DOE) to clean up two uranium mill tailings processing sites near Slick Rock, Colorado, in San Miguel County. The purpose of the cleanup is to reduce the potential health effects associated with the radioactive materials remaining on the sites and on vicinity properties (VP) associated with the sites. The US Environmental Protection Agency (EPA) promulgated standards for the UMTRCA that contained measures to control the contaminated materials and to protect the groundwater from further degradation. Remedial actions at the Slick Rock sites must be performed in accordance with these standards and with the concurrence of the US Nuclear Regulatory Commission (NRC)

  2. Summary of the engineering assessment of inactive uranium mill tailings: Slick Rock sites, Slick Rock, Colorado

    International Nuclear Information System (INIS)

    Ford, Bacon and Davis Utah, Inc., has reevaluated the Slick Rock sites in order to revise the October 1977 engineering assessment of the problems resulting from the existence of radioactive uranium mill tailings at Slick Rock, Colorado. This engineering assessment has included the preparation of topographic maps, the performance of core drillings and volumes of tailings and radiation exposures of individuals and nearby populations, the investigations of site hydrology and meteorology, and the evaluation and costing of alternative corrective actions. Radon gas released from the 387,000 tons of tailings at the Slick Rock sites constitutes the most significant environmental impact, although windblown tailings and external gamma radiation also are factors. The five alternative actions presented in this engineering assessment include millsite decontamination with the addition of 3 m of stabilization cover material, consolidation of the piles, and removal of the tailings to remote disposal sites and decontamination of the tailings sites. Cost estimates for the five options range from about $6,800,000 for stabilization in-place, to about $11,000,000 for disposal at a distance of about 6.5 mi. Three principal alternatives for the reprocessing of the Slick Rock tailings were examined: heap leaching; treatment at an existing mill; and reprocessing at a new conventional mill constructed for tailings reprocessing. The cost of the uranium recovered would be over $800/lb of U3O8 whether by conventional or heap leach plant processes. The spot market price for uranium was $25/lb early in 1981. Therefore, reprocessing the tailings for uranium recovery is not economically attractive at present, nor for the foreseeable future

  3. Engineering assessment of inactive uranium mill tailings: Slick Rock sites, Slick Rock, Colorado

    Energy Technology Data Exchange (ETDEWEB)

    None

    1981-09-01

    Ford, Bacon and Davis Utah, Inc., has reevaluated the Slick Rock sites in order to revise the October 1977 engineering radioactive uranium mill tailings at Slick Rock, Colorado. This engineering assessment has included the preparation of topographic maps, the performance of core drillings and radiometric measurements sufficient to determine areas and volumes of tailings and radiation exposures of individuals and nearby populations, the investigations of site hydrology and meteorology, and the evaluation and costing of alternative corrective actions. Radon gas released from the 387,000 tons of tailings at the Slick Rock sites constitutes the most significant environmental impact, although windblown tailings and external gamma radiation also are factors. The five alternative actions presented in this engineering assessment include millsite decontamination with the addition of 3 m of stabilization cover material, consolidation of the piles, and removal of the tailings to remote disposal sites and decontamination of the tailings sites. Cost estimates for the five options range from about $6,800,000 for stabilization in-place, to about $11,000,000 for disposal at a distance of about 6.5 mi. Three principal alternatives for the reprocessing of the Slick Rock tailings were examined: heap leaching; treatment at an existing mill; and reprocessing at a new conventional mill constructed for tailings reprocessing. The cost of the uranium recovered would be over $800/lb of U/sub 3/O/sub 8/ whether by conventional or heap leach plant processes. The spot market price for uranium was $25/lb early in 1981. Therefore, reprocessing the tailings for uranium recovery is not economically attractive at present, nor for the foreseeable future.

  4. Long-term surveillance plan for the Burro Canyon disposal cell Slick Rock, Colorado

    International Nuclear Information System (INIS)

    This long-term surveillance plan (LTSP) describes the U.S. Department of Energy (DOE) long-term care program for the Uranium Mill Tailings Remedial Action (UMTRA) Project Burro Canyon disposal cell in San Miguel County, Colorado. The U.S. Nuclear Regulatory Commission (NRC) developed regulations for the issuance of a general license for the custody and long-term care of UMTRA Project disposal sites in 10 CFR Part 40. The purpose of this general license is to ensure that the UMTRA Project disposal sites are cared for in a manner that protects the public health and safety and the environment. Before each disposal site is licensed, the NRC requires the DOE to submit a site-specific LTSP. The DOE prepared this LTSP to meet this requirement for the Burro Canyon disposal cell. The general license becomes effective when the NRC concurs with the DOE's determination that remedial action is complete at the Burro Canyon disposal cell and the NRC formally accepts this LTSP. Attachment 1 contains the concurrence letters from NRC. This LTSP describes the long-term surveillance program the DOE has implemented to ensure that the Burro Canyon disposal cell performs as designed. The program is based on site inspections to identify threats to disposal cell integrity. Ground water monitoring will not be required at the Burro Canyon disposal cell because the ground water protection strategy is supplemental standards based on low yield from the uppermost aquifer. The LTSP is based on the UMTRA Project's long-term surveillance program guidance and meets the requirements of 10 CFR 40.27(b) and 40 CFR 192.03

  5. Environmental assessment of remedial action at the Slick Rock uranium mill tailings sites, Slick Rock, Colorado

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-01-01

    The Uranium Mill Tailings Radiation Control Act of 1978, hereafter referred to as the UMTRCA, authorized the US Department of Energy (DOE) to clean up two uranium mill tailings processing sites near Slick Rock, Colorado, in San Miguel County. The purpose of the cleanup is to reduce the potential health effects associated with the radioactive materials remaining on the processing sites and on vicinity properties (VPs) associated with the sites. The US Environmental Protection Agency (EPA) promulgated standards for the UMTRCA that contained measures to control the contaminated materials and to protect the ground water from further degradation. The sites contain concrete foundations of mill buildings, tailings piles, and areas contaminated by windblown and waterborne radioactive tailings materials. The proposed action is to remediate the UC and NC sites by removing all contaminated materials within the designated site boundaries or otherwise associated with the sites, and relocating them to, and stabilizing them at, a location approximately 5 road mi (8 km) northeast of the processing sites on land administered by the US Bureau of Land Management (BLM). Remediation would be performed by the DOE`s Uranium Mill Tailings Remedial Action (UMTRA) Project.

  6. Environmental assessment of remedial action at the Slick Rock uranium mill tailings sites, Slick Rock, Colorado

    International Nuclear Information System (INIS)

    The Uranium Mill Tailings Radiation Control Act of 1978, hereafter referred to as the UMTRCA, authorized the US Department of Energy (DOE) to clean up two uranium mill tailings processing sites near Slick Rock, Colorado, in San Miguel County. The purpose of the cleanup is to reduce the potential health effects associated with the radioactive materials remaining on the processing sites and on vicinity properties (VPs) associated with the sites. The US Environmental Protection Agency (EPA) promulgated standards for the UMTRCA that contained measures to control the contaminated materials and to protect the ground water from further degradation. The sites contain concrete foundations of mill buildings, tailings piles, and areas contaminated by windblown and waterborne radioactive tailings materials. The proposed action is to remediate the UC and NC sites by removing all contaminated materials within the designated site boundaries or otherwise associated with the sites, and relocating them to, and stabilizing them at, a location approximately 5 road mi (8 km) northeast of the processing sites on land administered by the US Bureau of Land Management (BLM). Remediation would be performed by the DOE's Uranium Mill Tailings Remedial Action (UMTRA) Project

  7. Environmental assessment of remedial action at the Slick Rock uranium mill tailings sites, Slick Rock, Colorado

    International Nuclear Information System (INIS)

    The Uranium Mill Tailings Radiation Control Act of 1978 (42 USC section 7901 et seq.), hereafter referred to as the UMTRCA, authorized the US Department of Energy (DOE) to clean up two uranium mill tailings processing sites near Slick Rock, Colorado, in San Miquel County. Contaminated materials cover an estimated 63 acres of the Union Carbide (UC) processing site and 15 ac of the North Continent (NC) processing site. The sites are within 1 mile of each other and are adjacent to the Dolores River. The sites contain concrete foundations of mill buildings, tailings piles, and areas contaminated by windblown and waterborne radioactive tailings materials. The total estimated volume of contaminated materials is approximately 621,300 cubic yards (yd3). In addition to the contamination in the two processing site areas, four VPs were found to contain contamination. As a result of the tailings being exposed to the environment, contamination associated with the UC and NC sites has leached into shallow ground water. Surface water has not been affected. The closest residence is approximately 0.3 air mi from either site. The proposed action is to remediate the UC and NC sites by removing all contaminated materials within the designing site boundaries or otherwise associated with the sites, and relocating them to, and stabilizing them at, a location approximately 5 road mi northeast of the sites on land administered by the Bureau of Land Management (BLM)

  8. Environmental assessment of remedial action at the slick rock Uranium Mill Tailings sites Slick Rock, Colorado

    Energy Technology Data Exchange (ETDEWEB)

    1994-09-01

    The Uranium Mill Tailings Radiation Control Act of 1978 (42 USC {section} 7901 et seq.), hereafter referred to as the UMTRCA, authorized the U.S. Department of Energy (DOE) to clean up two uranium mill tailings processing sites near Slick Rock, Colorado, in San Miguel County. The purpose of the cleanup is to reduce the potential health effects associated with the radioactive materials remaining on the sites and on vicinity properties (VPs) associated with the sites. Contaminated materials cover an estimated 55 acres of the Union Carbide (UC) processing site and 12 ac of the North Continent (NC) processing site. The total estimated volume of contaminated materials is approximately 61 8,300 cubic yards. In addition to the contamination in the two processing site areas, four VPs were found to contain contamination. As a result of the tailings being exposed to the environment, contamination associated with the UC and NC sites has leached into shallow ground water. Surface water has not been affected. The closest residence is approximately 0.3 air mi from either site. The proposed action is to remediate the UC and NC sites by removing all contaminated materials within the designated site boundaries or otherwise associated with the sites, and relocating them to, and stabilizing them at, a location approximately 5 road mi (8 km) northeast of the sites on land administered by the Bureau of Land Management (BLM). Remediation would be performed by the DOE`s Uranium Mill Tailings Remedial Action (UMTRA) Project. All solid contaminated materials would be buried under 5 feet (ft) of rock and soil materials. The proposed disposal site area is currently used by ranchers for cattle grazing over a 7-month period. The closest residence to the proposed disposal site is 2 air mi. An estimated 44 ac of land would be permanently transferred from the BLM to the DOE and restricted from future use.

  9. Environmental assessment of remedial action at the slick rock Uranium Mill Tailings sites Slick Rock, Colorado

    International Nuclear Information System (INIS)

    The Uranium Mill Tailings Radiation Control Act of 1978 (42 USC section 7901 et seq.), hereafter referred to as the UMTRCA, authorized the U.S. Department of Energy (DOE) to clean up two uranium mill tailings processing sites near Slick Rock, Colorado, in San Miguel County. The purpose of the cleanup is to reduce the potential health effects associated with the radioactive materials remaining on the sites and on vicinity properties (VPs) associated with the sites. Contaminated materials cover an estimated 55 acres of the Union Carbide (UC) processing site and 12 ac of the North Continent (NC) processing site. The total estimated volume of contaminated materials is approximately 61 8,300 cubic yards. In addition to the contamination in the two processing site areas, four VPs were found to contain contamination. As a result of the tailings being exposed to the environment, contamination associated with the UC and NC sites has leached into shallow ground water. Surface water has not been affected. The closest residence is approximately 0.3 air mi from either site. The proposed action is to remediate the UC and NC sites by removing all contaminated materials within the designated site boundaries or otherwise associated with the sites, and relocating them to, and stabilizing them at, a location approximately 5 road mi (8 km) northeast of the sites on land administered by the Bureau of Land Management (BLM). Remediation would be performed by the DOE's Uranium Mill Tailings Remedial Action (UMTRA) Project. All solid contaminated materials would be buried under 5 feet (ft) of rock and soil materials. The proposed disposal site area is currently used by ranchers for cattle grazing over a 7-month period. The closest residence to the proposed disposal site is 2 air mi. An estimated 44 ac of land would be permanently transferred from the BLM to the DOE and restricted from future use

  10. Environmental assessment of remedial action at the Slick Rock uranium mill tailings sites Slick Rock, Colorado. Draft

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1993-06-01

    The Uranium Mill Tailings Radiation Control Act of 1978 (UMTRCA) authorized the US Department of Energy (DOE) to clean up two uranium mill tailings processing sites near Slick Rock, Colorado, in San Miguel County. The purpose of the cleanup is to reduce the potential health effects associated with the radioactive materials remaining on the sites and on vicinity properties (VP) associated with the sites. The US Environmental Protection Agency (EPA) promulgated standards for the UMTRCA that contained measures to control the contaminated materials and to protect the groundwater from further degradation. Remedial actions at the Slick Rock sites must be performed in accordance with these standards and with the concurrence of the US Nuclear Regulatory Commission (NRC).

  11. Environmental assessment of remedial action at the Slick Rock uranium mill tailings sites, Slick Rock, Colorado. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    1994-09-01

    The Uranium Mill Tailings Radiation Control Act of 1978 (42 USC {section}7901 et seq.), hereafter referred to as the UMTRCA, authorized the US Department of Energy (DOE) to clean up two uranium mill tailings processing sites near Slick Rock, Colorado, in San Miquel County. Contaminated materials cover an estimated 63 acres of the Union Carbide (UC) processing site and 15 ac of the North Continent (NC) processing site. The sites are within 1 mile of each other and are adjacent to the Dolores River. The sites contain concrete foundations of mill buildings, tailings piles, and areas contaminated by windblown and waterborne radioactive tailings materials. The total estimated volume of contaminated materials is approximately 621,300 cubic yards (yd{sup 3}). In addition to the contamination in the two processing site areas, four VPs were found to contain contamination. As a result of the tailings being exposed to the environment, contamination associated with the UC and NC sites has leached into shallow ground water. Surface water has not been affected. The closest residence is approximately 0.3 air mi from either site. The proposed action is to remediate the UC and NC sites by removing all contaminated materials within the designing site boundaries or otherwise associated with the sites, and relocating them to, and stabilizing them at, a location approximately 5 road mi northeast of the sites on land administered by the Bureau of Land Management (BLM).

  12. Engineering assessment of inactive uranium mill tailings, Slick Rock sites, Slick Rock, Colorado. Phase II, Title I

    Energy Technology Data Exchange (ETDEWEB)

    None

    1977-10-01

    Ford, Bacon and Davis Utah Inc. has performed an engineering assessment of the problems resulting from the existence of radioactive uranium mill tailings at the two millsites in Slick Rock, Colorado. The Phase II, Title I services include the preparation of topographic maps, the performance of core drillings and radiometric measurements sufficient to determine areas and volumes of tailings and other radium-contaminated materials, the evaluation of resulting radiation exposures of individuals residing nearby, the investigation of site hydrology and meteorology, and the evaluation and costing of alternative corrective actions. The Union Carbide site has 350,000 tons of tailings and the North Continent site now owned by Union Carbide has 37,000 tons of tailings. Both tailings piles have been stabilized in accordance with regulations of the State of Colorado. Radon gas release from the tailings on the sites constitute the most significant environmental impact, although windblown tailings and external gamma radiation are also factors. The sparse population and relatively low radiation levels yield minimal immediate environmental impact. Hence the three alternative actions presented are directed towards restricting access to the sites (Option I), and returning the windblown tailings to the piles and stabilizing the piles with cover material (Option II), and consolidating the two piles on the UC site and stabilizing with 2 ft of cover (Option III). Fencing around the tailings piles is included in all options. Options II and III provide 2 ft of cover material on the tailings. Costs of the options range from $370,000 to $1,100,000. Reprocessing the tailings for uranium is not economically feasible.

  13. Engineering assessment of inactive uranium mill tailings, Slick Rock sites, Slick Rock, Colorado. Phase II, Title I

    International Nuclear Information System (INIS)

    Ford, Bacon and Davis Utah Inc. has performed an engineering assessment of the problems resulting from the existence of radioactive uranium mill tailings at the two millsites in Slick Rock, Colorado. The Phase II, Title I services include the preparation of topographic maps, the performance of core drillings and radiometric measurements sufficient to determine areas and volumes of tailings and other radium-contaminated materials, the evaluation of resulting radiation exposures of individuals residing nearby, the investigation of site hydrology and meteorology, and the evaluation and costing of alternative corrective actions. The Union Carbide site has 350,000 tons of tailings and the North Continent site now owned by Union Carbide has 37,000 tons of tailings. Both tailings piles have been stabilized in accordance with regulations of the State of Colorado. Radon gas release from the tailings on the sites constitute the most significant environmental impact, although windblown tailings and external gamma radiation are also factors. The sparse population and relatively low radiation levels yield minimal immediate environmental impact. Hence the three alternative actions presented are directed towards restricting access to the sites (Option I), and returning the windblown tailings to the piles and stabilizing the piles with cover material (Option II), and consolidating the two piles on the UC site and stabilizing with 2 ft of cover (Option III). Fencing around the tailings piles is included in all options. Options II and III provide 2 ft of cover material on the tailings. Costs of the options range from $370,000 to $1,100,000. Reprocessing the tailings for uranium is not economically feasible

  14. Remedial action and site design for stabilization of the inactive uranium mill tailings sites at Slick Rock, Colorado

    International Nuclear Information System (INIS)

    This report presents geologic considerations that are pertinent to the Remedial Action Plan for Slick Rock mill tailings. Topics covered include regional geology, site geology, geologic stability, and geologic suitability

  15. Baseline risk assessment of ground water contamination at the uranium mill tailings sites near Slick Rock, Colorado

    International Nuclear Information System (INIS)

    This baseline risk assessment of ground water contamination at the uranium mill tailings sites near Slick Rock, Colorado, evaluates potential public health and environmental impacts resulting from ground water contamination at the former North Continent (NC) and Union Carbide (UC) uranium mill processing sites. The tailings at these sites will be placed in a disposal cell at the proposed Burro Canyon, Colorado, site. The US Department of Energy (DOE) anticipates the start of the first phase remedial action by the spring of 1995 under the direction of the DOE's Uranium Mill Tailings Remedial Action (UMTRA) Project. The second phase of the UMTRA Project will evaluate ground water contamination. This baseline risk assessment is the first site-specific document for these sites under the Ground Water Project. It will help determine the compliance strategy for contaminated ground water at the site. In addition, surface water and sediment are qualitatively evaluated in this report

  16. Baseline risk assessment of ground water contamination at the uranium mill tailings sites near Slick Rock, Colorado

    Energy Technology Data Exchange (ETDEWEB)

    1994-11-01

    This baseline risk assessment of ground water contamination at the uranium mill tailings sites near Slick Rock, Colorado, evaluates potential public health and environmental impacts resulting from ground water contamination at the former North Continent (NC) and Union Carbide (UC) uranium mill processing sites. The tailings at these sites will be placed in a disposal cell at the proposed Burro Canyon, Colorado, site. The US Department of Energy (DOE) anticipates the start of the first phase remedial action by the spring of 1995 under the direction of the DOE`s Uranium Mill Tailings Remedial Action (UMTRA) Project. The second phase of the UMTRA Project will evaluate ground water contamination. This baseline risk assessment is the first site-specific document for these sites under the Ground Water Project. It will help determine the compliance strategy for contaminated ground water at the site. In addition, surface water and sediment are qualitatively evaluated in this report.

  17. Engineering assessment of inactive uranium mill tailings, Slick Rock sites, Slick Rock, Colorado. A summary of the Phase II, Title I

    International Nuclear Information System (INIS)

    Ford, Bacon and Davis Utah Inc. has performed an engineering assessment of the problems resulting from the existence of radioactive uranium mill tailings at the two millsites in Slick Rock, Colorado. The Phase II, Title I services include the preparation of topographic maps, the performance of core drillings and radiometric measurements sufficient to determine areas and volumes of tailings and other radium-contaminated materials, the evaluation of resulting radiation exposures of individuals residing nearby, the investigation of site hydrology and meteorology, and the evaluation and costing of alternative corrective actions. The Union Carbide site has 350,000 tons of tailings and the North Continent site now owned by Union Carbide has 37,000 tons of tailings. Both tailings piles have been stabilized in accordance with regulations of the State of Colorado. Radon gas release from the tailings on the sites constitute the most significant environmental impact, although windblown tailings and external gamma radiation are also factors. The sparse population and relatively low radiation levels yield minimal immediate environmental impact. Hence the three alternative actions presented are directed towards restricting access to the sites (Option I), and returning the windblown tailings to the piles and stabilizing the piles with cover material (Option II), and consolidating the two piles on the UC site and stabilizing with 2 ft of cover (Option III). Fencing around the tailings piles is included in all options. Options II and III provide 2 ft of cover material on the tailings. Costs of the options range from $370,000 to $1,100,000. Reprocessing the tailings for uranium is not economically feasible

  18. Remedial action and site design for stabilization of the inactive uranium mill tailings sites at Slick Rock, Colorado. Attachment 2, Geology report

    Energy Technology Data Exchange (ETDEWEB)

    1993-07-01

    This report presents geologic considerations that are pertinent to the Remedial Action Plan for Slick Rock mill tailings. Topics covered include regional geology, site geology, geologic stability, and geologic suitability.

  19. Baseline risk assessment of ground water contamination at the Uranium Mill Tailings Sites near Slick Rock, Colorado. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-09-01

    Two UMTRA (Uranium Mill Tailings Remedial Action) Project sites are near Slick Rock, Colorado: the North Continent site and the Union Carbide site. Currently, no one uses the contaminated ground water at either site for domestic or agricultural purposes. However, there may be future land development. This risk assessment evaluates possible future health problems associated with exposure to contaminated ground water. Since some health problems could occur, it is recommended that the contaminated ground water not be used as drinking water.

  20. Baseline risk assessment of ground water contamination at the Uranium Mill Tailings Sites near Slick Rock, Colorado. Revision 1

    International Nuclear Information System (INIS)

    Two UMTRA (Uranium Mill Tailings Remedial Action) Project sites are near Slick Rock, Colorado: the North Continent site and the Union Carbide site. Currently, no one uses the contaminated ground water at either site for domestic or agricultural purposes. However, there may be future land development. This risk assessment evaluates possible future health problems associated with exposure to contaminated ground water. Since some health problems could occur, it is recommended that the contaminated ground water not be used as drinking water

  1. Radiological survey of the inactive uranium-mill tailings at Slick Rock, Colorado

    International Nuclear Information System (INIS)

    Results of a radiological survey of two inactive mill sites near Slick Rock, Colorado, in April 1976 are presented. One mill, referred to in this report as North Continent (NC), was operated primarily for recovery of radium and vanadium and, only briefly, uranium. The Union Carbide Corporation (UCC) mill produced a uranium concentrate for processing elsewhere and, although low-level contamination with 226Ra was widespread at this site, the concentration of this nuclide in tailings was much lower than at the NC site. The latter site also has an area with a high above-ground gamma dose rate (2700 μR/hr) and a high-surface 226Ra concentration (5800 pCi/g). This area, which is believed to have been a liquid disposal location during plant operations, is contained within a fence. A solid disposal area outside the present fence contains miscellaneous contaminated debris. The estimated concentration of 226Ra as a function of depth, based on gamma hole-logging data, is presented for 27 holes drilled at the two sites

  2. Cell volume changes regulate slick (Slo2.1, but not slack (Slo2.2 K+ channels.

    Directory of Open Access Journals (Sweden)

    Maria A Tejada

    Full Text Available Slick (Slo2.1 and Slack (Slo2.2 channels belong to the family of high-conductance K+ channels and have been found widely distributed in the CNS. Both channels are activated by Na+ and Cl- and, in addition, Slick channels are regulated by ATP. Therefore, the roles of these channels in regulation of cell excitability as well as ion transport processes, like regulation of cell volume, have been hypothesized. It is the aim of this work to evaluate the sensitivity of Slick and Slack channels to small, fast changes in cell volume and to explore mechanisms, which may explain this type of regulation. For this purpose Slick and Slack channels were co-expressed with aquaporin 1 in Xenopus laevis oocytes and cell volume changes of around 5% were induced by exposure to hypotonic or hypertonic media. Whole-cell currents were measured by two electrode voltage clamp. Our results show that Slick channels are dramatically stimulated (196% of control by cell swelling and inhibited (57% of control by a decrease in cell volume. In contrast, Slack channels are totally insensitive to similar cell volume changes. The mechanism underlining the strong volume sensitivity of Slick channels needs to be further explored, however we were able to show that it does not depend on an intact actin cytoskeleton, ATP release or vesicle fusion. In conclusion, Slick channels, in contrast to the similar Slack channels, are the only high-conductance K+ channels strongly sensitive to small changes in cell volume.

  3. Remedial action plan and site design for stabilization of the inactive uranium mill tailings sites at Slick Rock, Colorado: Appendix A to Attachment 3, tables; Preliminary final

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-03-01

    This appendix contains the supporting tables for the remedial action plan for uranium mill tailings sites at Slick Rock, CO. The tables contain monitoring well information, background groundwater quality data, regulated constituent summaries, tailings pore fluid sample analyses, and other data for each of the sites studied.

  4. Finding of no significant impact proposed remedial action at two uranium processing sites near Slick Rock, Colorado

    Energy Technology Data Exchange (ETDEWEB)

    1994-10-01

    The U.S. Department of Energy (DOE) has prepared an environmental assessment (EA) (DOE/EA-0339) of the proposed remedial action at two uranium processing sites near Slick Rock in San Miguel County, Colorado. These sites contain radioactively contaminated materials that would be removed and stabilized at a remote location. Based on the information and analyses in the EA, the DOE has determined that the proposed action does not constitute a major Federal action significantly affecting the quality of the human environment within the meaning of the National Environmental Policy Act (NEPA) of 1969 (42 U.S.C. 4321 et seq.), as amended. Therefore, preparation of an environmental impact statement is not required, and the DOE is issuing this Finding of No Significant Impact (ONSI).

  5. Remedial action and site design for stabilization of the inactive uranium mill tailings sites at Slick Rock, Colorado. Attachment 2, Geology report: Appendix B, Preliminary final

    Energy Technology Data Exchange (ETDEWEB)

    1994-03-01

    Detailed investigations of geologic, geomorphic, and seismic conditions at the Burro Canyon site were conducted by the US Department of Energy (DOE) as a disposal site for the tailings at two processing sites near the Slick Rock, Colorado, post office. The purposes of these studies are basic site characterization and identification of potential geologic hazards that could affect long-term site stability. Subsequent engineering studies (e.g., analyses of hydrologic and liquefaction hazards) used the data developed in these studies. The geomorphic analysis was employed in the design of effective erosion protection. Studies of the regional and local seismotectonic setting, which included a detailed search for possible capable faults within a 65-km radius of the site, provided the basis for seismic design parameters.

  6. Remedial Action Plan and Site design for stabilization of the inactive Uranium Mill Tailings sites at Slick Rock, Colorado: Revision 1. Remedial action selection report, Attachment 2, geology report, Attachment 3, ground water hydrology report, Attachment 4, water resources protection strategy. Final

    International Nuclear Information System (INIS)

    The Slick Rock uranium mill tailings sites are located near the small community of Slick Rock, in San Miguel County, Colorado. There are two designated Uranium Mill Tailings Remedial Action (UMTRA) Project sites at Slick Rock: the Union Carbide site and the North Continent site. Both sites are adjacent to the Dolores River. The sites contain former mill building concrete foundations, tailings piles, demolition debris, and areas contaminated by windblown and waterborne radioactive materials. The total estimated volume of contaminated materials is approximately 621,000 cubic yards (475,000 cubic meters). In addition to the contamination at the two processing site areas, 13 vicinity properties were contaminated. Contamination associated with the UC and NC sites has leached into ground water. Pursuant to the requirements of the Uranium Mill Tailings Radiation Control Act (UMTRCA) (42 USC section 7901 et seq.), the proposed remedial action plan (RAP) will satisfy the final US Environmental Protection Agency (EPA) standards in 40 CFR Part 192 (60 FR 2854) for cleanup, stabilization, and control of the residual radioactive material (RRM) (tailings and other contaminated materials) at the disposal site at Burro Canyon. The requirements for control of the RRM (Subpart A) will be satisfied by the construction of an engineered disposal cell. The proposed remedial action will consist of relocating the uranium mill tailings, contaminated vicinity property materials, demolition debris, and windblown/weaterborne materials to a permanent repository at the Burro Canyon disposal site. The site is approximately 5 road mi (8 km) northeast of the mill sites on land recently transferred to the DOE by the Bureau of Land Management

  7. Remedial Action Plan and Site design for stabilization of the inactive Uranium Mill Tailings sites at Slick Rock, Colorado: Revision 1. Remedial action selection report, Attachment 2, geology report, Attachment 3, ground water hydrology report, Attachment 4, water resources protection strategy. Final

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-09-01

    The Slick Rock uranium mill tailings sites are located near the small community of Slick Rock, in San Miguel County, Colorado. There are two designated Uranium Mill Tailings Remedial Action (UMTRA) Project sites at Slick Rock: the Union Carbide site and the North Continent site. Both sites are adjacent to the Dolores River. The sites contain former mill building concrete foundations, tailings piles, demolition debris, and areas contaminated by windblown and waterborne radioactive materials. The total estimated volume of contaminated materials is approximately 621,000 cubic yards (475,000 cubic meters). In addition to the contamination at the two processing site areas, 13 vicinity properties were contaminated. Contamination associated with the UC and NC sites has leached into ground water. Pursuant to the requirements of the Uranium Mill Tailings Radiation Control Act (UMTRCA) (42 USC {section}7901 et seq.), the proposed remedial action plan (RAP) will satisfy the final US Environmental Protection Agency (EPA) standards in 40 CFR Part 192 (60 FR 2854) for cleanup, stabilization, and control of the residual radioactive material (RRM) (tailings and other contaminated materials) at the disposal site at Burro Canyon. The requirements for control of the RRM (Subpart A) will be satisfied by the construction of an engineered disposal cell. The proposed remedial action will consist of relocating the uranium mill tailings, contaminated vicinity property materials, demolition debris, and windblown/weaterborne materials to a permanent repository at the Burro Canyon disposal site. The site is approximately 5 road mi (8 km) northeast of the mill sites on land recently transferred to the DOE by the Bureau of Land Management.

  8. Remedial action plan and site design for stabilization of the inactive uranium mill tailings sites at Slick Rock, Colorado: Remedial Action Selection Report. Preliminary final

    Energy Technology Data Exchange (ETDEWEB)

    1994-03-01

    This proposed remedial action plan incorporates the results of detailed investigation of geologic, geomorphic, and seismic conditions at the proposed disposal site. The proposed remedial action will consist of relocating the uranium mill tailings, contaminated vicinity property materials, demolition debris, and windblown/waterborne materials to a permanent repository at the proposed Burro Canyon disposal cell. The proposed disposal site will be geomorphically stable. Seismic design parameters were developed for the geotechnical analyses of the proposed cell. Cell stability was analyzed to ensure long-term performance of the disposal cell in meeting design standards, including slope stability, settlement, and liquefaction potential. The proposed cell cover and erosion protection features were also analyzed and designed to protect the RRM (residual radioactive materials) against surface water and wind erosion. The location of the proposed cell precludes the need for permanent drainage or interceptor ditches. Rock to be used on the cell top-, side-, and toeslopes was sized to withstand probable maximum precipitation events.

  9. Differential distribution of the sodium-activated potassium channels slick and slack in mouse brain.

    Science.gov (United States)

    Rizzi, Sandra; Knaus, Hans-Günther; Schwarzer, Christoph

    2016-07-01

    The sodium-activated potassium channels Slick (Slo2.1, KCNT2) and Slack (Slo2.2, KCNT1) are high-conductance potassium channels of the Slo family. In neurons, Slick and Slack channels are involved in the generation of slow afterhyperpolarization, in the regulation of firing patterns, and in setting and stabilizing the resting membrane potential. The distribution and subcellular localization of Slick and Slack channels in the mouse brain have not yet been established in detail. The present study addresses this issue through in situ hybridization and immunohistochemistry. Both channels were widely distributed and exhibited distinct distribution patterns. However, in some brain regions, their expression overlapped. Intense Slick channel immunoreactivity was observed in processes, varicosities, and neuronal cell bodies of the olfactory bulb, granular zones of cortical regions, hippocampus, amygdala, lateral septal nuclei, certain hypothalamic and midbrain nuclei, and several regions of the brainstem. The Slack channel showed primarily a diffuse immunostaining pattern, and labeling of cell somata and processes was observed only occasionally. The highest Slack channel expression was detected in the olfactory bulb, lateral septal nuclei, basal ganglia, and distinct areas of the midbrain, brainstem, and cerebellar cortex. In addition, comparing our data obtained from mouse brain with a previously published study on rat brain revealed some differences in the expression and distribution of Slick and Slack channels in these species. J. Comp. Neurol. 524:2093-2116, 2016. © 2015 The Authors The Journal of Comparative Neurology Published by Wiley Periodicals, Inc. PMID:26587966

  10. Experimental study on spectral responses of offshore oil slick

    Institute of Scientific and Technical Information of China (English)

    LU YingCheng; TIAN QingJiu; WANG JingJing; WANG XiangCheng; QI XiaoPing

    2008-01-01

    Using the seawater taken from Liaodong Bay and crude oil taken from Liaohe Oilfield, a laboratory experiment was designed to study the change of reflectance spectrum of artificial offshore oil slick with its thickness and to identify the spectrum ranges suitable for quantifying the thickness of the oil slick.During the experiment, crude oil was continuously dropped into the seawater to generate artificial oil slick with different thicknesses. After every drop of crude oil was added, reflectance spectrum of the oil slick was measured with a high resolution spectroradiometer (ASD FieldSpec Pro FR). The influence of oil slick thickness on its reflectance spectrum was explored through statistical analysis. The results show that the reflectance of oil slick changes marginally with oil slick thickness and higher than that of seawater in infrared band from 1150 to 2500 nm. This spectrum range can be practically used to distinguish oil slick from seawater. In the spectrum range from 400 to 1150 nm, the reflectance of oil slick decreases with its thickness. The negative power function is the best-fit function expressing the relationship between the reflectance and thickness. The spectral characteristics of oil slick are very distinct at 550 and 645 nm. They are the best wavelengths for monitoring the existence of offshore oil slick and estimating its thickness.

  11. Oil Slick Characterization Using Synthetic Aperture Radar

    Science.gov (United States)

    Jones, C. E.; Breivik, O.; Brekke, C.; Skrunes, S.; Holt, B.

    2015-12-01

    Oil spills are a hazard worldwide with potential of causing high impact disasters, and require an active oil spill response capability to protect personnel, the ecosystem, and the energy supply. As the amount of oil in traditionally accessible reserves decline, there will be increasing oil extraction from the Arctic and deep-water wells, both new sources with high risk and high cost for monitoring and response. Although radar has long been used for mapping the spatial extent of oil slicks, it is only since the Deepwater Horizon spill that synthetic aperture radar (SAR) has been shown capable of characterizing oil properties within a slick, and therefore useful for directing response to the recoverable thicker slicks or emulsions. Here we discuss a 2015 Norwegian oil-on-water spill experiment in which emulsions of known quantity and water-to-oil ratio along with a look-alike slick of plant oil were released in the North Sea and imaged with polarimetric SAR (PolSAR) by NASA's UAVSAR instrument for several hours following release. During the experiment, extensive in situ measurements were made from ship or aircraft with meteorological instruments, released drift buoys, and optical/IR imagers. The experiment was designed to provide validation data for development of a physical model relating polarization-dependent electromagnetic scattering to the dielectric properties of oil mixed with ocean water, which is the basis for oil characterization with SAR. Data were acquired with X-, C-, and L-band satellite-based SARs to enable multi-frequency comparison of characterization capabilities. In addition, the data are used to develop methods to differentiate mineral slicks from biogenic look-alikes, and to better understand slick weathering and dispersion. The results will provide a basis for modeling oil-in-ice spills, currently a high priority for nations involved in Arctic oil exploration. Here we discuss the Norwegian experiment, the validation data, and the results of

  12. Radarsat observations and forecasting of oil slick trajectory movements

    Institute of Scientific and Technical Information of China (English)

    Maged Marghany

    2004-01-01

    RADARSAT data have a potential role for coastal pollution monitoring. This study presents a new approach to detect and forecast oil slick trajectory movements. The oil slick trajectory movements is based on the tidal current effects and Fay's algorithm for oil slick spreading mechanisms. The oil spill trajectory model contains the integration between Doppler frequency shift model and Lagrangian model. Doppler frequency shift model implemented to simulate tidal current pattern from RADARSAT data while the Lagrangian model used to predict oil spill spreading pattern. The classical Fay's algorithm was implemented with the two models to simulate the oil spill trajectory movements.The study shows that the slick lengths are effected by tidal current V component with maximum velocity of 1.4 m/s. This indicates thatoil slick trajectory path is moved towards the north direction. The oil slick parcels are accumulated along the coastline after 48 h. Theanalysis indicated that tidal current V components were the dominant forcing for oil slick spreading.

  13. Natural and unnatural oil slicks in the Gulf of Mexico

    Science.gov (United States)

    MacDonald, I. R.; Garcia-Pineda, O.; Beet, A.; Daneshgar Asl, S.; Feng, L.; Graettinger, G.; French-McCay, D.; Holmes, J.; Hu, C.; Huffer, F.; Leifer, I.; Muller-Karger, F.; Solow, A.; Silva, M.; Swayze, G.

    2015-12-01

    When wind speeds are 2-10 m s-1, reflective contrasts in the ocean surface make oil slicks visible to synthetic aperture radar (SAR) under all sky conditions. Neural network analysis of satellite SAR images quantified the magnitude and distribution of surface oil in the Gulf of Mexico from persistent, natural seeps and from the Deepwater Horizon (DWH) discharge. This analysis identified 914 natural oil seep zones across the entire Gulf of Mexico in pre-2010 data. Their ˜0.1 µm slicks covered an aggregated average of 775 km2. Assuming an average volume of 77.5 m3 over an 8-24 h lifespan per oil slick, the floating oil indicates a surface flux of 2.5-9.4 × 104 m3 yr-1. Oil from natural slicks was regionally concentrated: 68%, 25%, 7%, and ecological impact. The most likely causes were increased applications of dispersant and surface burning operations.

  14. Origins and features of oil slicks in the Bohai Sea detected from satellite SAR images.

    Science.gov (United States)

    Ding, Yi; Cao, Conghua; Huang, Juan; Song, Yan; Liu, Guiyan; Wu, Lingjuan; Wan, Zhenwen

    2016-05-15

    Oil slicks were detected using satellite Synthetic Aperture Radar (SAR) images in 2011. We investigated potential origins and regional and seasonal features of oil slick in the Bohai Sea. Distance between oil slicks and potential origins (ships, seaports, and oil exploitation platforms) and the angle at which oil slicks move relative to potential driving forces were evaluated. Most oil slicks were detected along main ship routes rather than around seaports and oil exploitation platforms. Few oil slicks were detected within 20km of seaports. Directions of oil slicks movement were much more strongly correlated with directions of ship routes than with directions of winds and currents. These findings support the premise that oil slicks in the Bohai Sea most likely originate from illegal disposal of oil-polluted wastes from ships. Seasonal variation of oil slicks followed an annual cycle, with a peak in August and a trough in December. PMID:26988390

  15. Origins and features of oil slicks in the Bohai Sea detected from satellite SAR images.

    Science.gov (United States)

    Ding, Yi; Cao, Conghua; Huang, Juan; Song, Yan; Liu, Guiyan; Wu, Lingjuan; Wan, Zhenwen

    2016-05-15

    Oil slicks were detected using satellite Synthetic Aperture Radar (SAR) images in 2011. We investigated potential origins and regional and seasonal features of oil slick in the Bohai Sea. Distance between oil slicks and potential origins (ships, seaports, and oil exploitation platforms) and the angle at which oil slicks move relative to potential driving forces were evaluated. Most oil slicks were detected along main ship routes rather than around seaports and oil exploitation platforms. Few oil slicks were detected within 20km of seaports. Directions of oil slicks movement were much more strongly correlated with directions of ship routes than with directions of winds and currents. These findings support the premise that oil slicks in the Bohai Sea most likely originate from illegal disposal of oil-polluted wastes from ships. Seasonal variation of oil slicks followed an annual cycle, with a peak in August and a trough in December.

  16. Space Radar Image of Oil Slicks

    Science.gov (United States)

    1994-01-01

    This is a radar image of an offshore drilling field about 150 km (93 miles) west of Bombay, India, in the Arabian Sea. The dark streaks are extensive oil slicks surrounding many of the drilling platforms, which appear as bright white spots. Radar images are useful for detecting and measuring the extent of oil seepages on the ocean surface, from both natural and industrial sources. The long, thin streaks extending from many of the platforms are spreading across the sea surface, pushed by local winds. The larger dark patches are dispersed slicks that were likely discharged earlier than the longer streaks, when the winds were probably from a different direction. The dispersed oil will eventually spread out over the more dense water and become a layer which is a single molecule thick. Many forms of oil, both from biological and from petroleum sources, smooth out the ocean surface, causing the area to appear dark in radar images. There are also two forms of ocean waves shown in this image. The dominant group of large waves (upper center) are called internal waves. These waves are formed below the ocean surface at the boundary between layers of warm and cold water and they appear in the radar image because of the way they change the ocean surface. Ocean swells, which are waves generated by winds, are shown throughout the image but are most distinct in the blue area adjacent to the internal waves. Identification of waves provide oceanographers with information about the smaller scale dynamic processes of the ocean. This image was acquired by the Spaceborne Imaging Radar-C/X-Band Synthetic Aperture Radar (SIR-C/X-SAR) aboard the space shuttle Endeavour on October 9, 1994. The colors are assigned to different frequencies and polarizations of the radar as follows: Red is L-band vertically transmitted, vertically received; green is the average of L-band vertically transmitted, vertically received and C-band vertically transmitted, vertically received; blue is C

  17. Turbulence Modelling of A Lock-Release Oil Slick

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    The motion of a lock-release oil slick as an immiscible two-fluid gravity current is numerically studied by a finite difference algorithm based on the volume of fluid (VOF) method for the basic formulation and a rigid cover approximation for the open free surface. Detailed numerical simulation with careful model validation reveals the existence of turbulence and the adaptability of the renormalization group (RNG) k-ε model for the Reynolds-stress closure in the case of the oil slick. The time evolution and spatial distribution of the mean velocity, turbulence kinetic energy and turbulent viscosity are characterized. The mechanism for the transition from an initial gravity-inertial phase to a second gravity-viscous phase is shown to be the relaminarization effect of the initially highly turbulent slick. Compared well with known theoretical analyses and experimental observations, the turbulence modeling results in self-similar spreading laws in terms of the fact that the oil slick passes through the initial gravity-inertial phase with the front speed decreasing as t-1/3 (where t is the time measured from lock release) and the second gravity-viscous phase with the front speed decreasing as t-5/8.

  18. PIP2 modulation of slick and slack K+ channels

    DEFF Research Database (Denmark)

    Tejada, Maria de los Angeles; Jensen, Lars Jørn; Klærke, Dan Arne

    2012-01-01

    Slick and Slack are members of the Slo family of high-conductance potassium channels. These channels are activated by Na(+) and Cl(-) and are highly expressed in the CNS, where they are believed to contribute to the resting membrane potential of neurons and the control of excitability. Herein, we...... provide evidence that Slick and Slack channels are regulated by the phosphoinositide PIP(2). Two stereoisomers of PIP(2) were able to exogenously activate Slick and Slack channels expressed in Xenopus oocytes, and in addition, it is shown that Slick and Slack channels are modulated by endogenous PIP(2......). The activating effect of PIP(2) appears to occur by direct interaction with lysine 306 in Slick and lysine 339 in Slack, located at the proximal C-termini of both channels. Overall, our data suggest that PIP(2) is an important regulator of Slick and Slack channels, yet it is not involved in the...

  19. Effect of film slicks on near-surface wind

    Science.gov (United States)

    Charnotskii, Mikhail; Ermakov, Stanislav; Ostrovsky, Lev; Shomina, Olga

    2016-09-01

    The transient effects of horizontal variation of sea-surface wave roughness due to surfactant films on near-surface turbulent wind are studied theoretically and experimentally. Here we suggest two practical schemes for calculating variations of wind velocity profiles near the water surface, the average short-wave roughness of which is varying in space and time when a film slick is present. The schemes are based on a generalized two-layer model of turbulent air flow over a rough surface and on the solution of the continuous model involving the equation for turbulent kinetic energy of the air flow. Wave tank studies of wind flow over wind waves in the presence of film slicks are described and compared with theory.

  20. Thermal infrared emissivity spectrum and its characteristics of crude oil slick covered seawater.

    Science.gov (United States)

    Xiong, Pan; Gu, Xing-Fai; Yu, Taol; Meng, Qing-Yan; Li, Jia-Guoi; Shi, Ji-xiang; Cheng, Yang; Wang, Liang; Liu, Wen-Song; Liu, Qi-Yuei; Zhao, Li-Min

    2014-11-01

    Detecting oil slick covered seawater surface using the thermal infrared remote sensing technology exists the advantages such as: oil spill detection with thermal infrared spectrum can be performed in the nighttime which is superior to visible spectrum, the thermal infrared spectrum is superior to detect the radiation characteristics of both the oil slick and the seawater compared to the mid-wavelength infrared spectrum and which have great potential to detect the oil slick thickness. And the emissivity is the ratio of the radiation of an object at a given temperature in normal range of the temperature (260-320 K) and the blackbody radiation under the same temperature , the emissivity of an object is unrelated to the temperature, but only is dependent with the wavelength and material properties. Using the seawater taken from Bohai Bay and crude oil taken from Gudao oil production plant of Shengli Oilfield in Dongying city of Shandong Province, an experiment was designed to study the characteristics and mechanism of thermal infrared emissivity spectrum of artificial crude oil slick covered seawater surface with its thickness. During the experiment, crude oil was continuously dropped into the seawater to generate artificial oil slick with different thicknesses. By adding each drop of crude oil, we measured the reflectivity of the oil slick in the thermal infrared spectrum with the Fourier transform infrared spectrometer (102F) and then calculated its thermal infrared emissivity. The results show that the thermal infrared emissivity of oil slick changes significantly with its thickness when oil slick is relatively thin (20-120 μm), which provides an effective means for detecting the existence of offshore thin oil slick In the spectrum ranges from 8 to 10 μm and from 13. 2 to 14 μm, there is a steady emissivity difference between the seawater and thin oil slick with thickness of 20 μm. The emissivity of oil slick changes marginally with oil slick thickness and

  1. Thermal infrared emissivity spectrum and its characteristics of crude oil slick covered seawater.

    Science.gov (United States)

    Xiong, Pan; Gu, Xing-Fai; Yu, Taol; Meng, Qing-Yan; Li, Jia-Guoi; Shi, Ji-xiang; Cheng, Yang; Wang, Liang; Liu, Wen-Song; Liu, Qi-Yuei; Zhao, Li-Min

    2014-11-01

    Detecting oil slick covered seawater surface using the thermal infrared remote sensing technology exists the advantages such as: oil spill detection with thermal infrared spectrum can be performed in the nighttime which is superior to visible spectrum, the thermal infrared spectrum is superior to detect the radiation characteristics of both the oil slick and the seawater compared to the mid-wavelength infrared spectrum and which have great potential to detect the oil slick thickness. And the emissivity is the ratio of the radiation of an object at a given temperature in normal range of the temperature (260-320 K) and the blackbody radiation under the same temperature , the emissivity of an object is unrelated to the temperature, but only is dependent with the wavelength and material properties. Using the seawater taken from Bohai Bay and crude oil taken from Gudao oil production plant of Shengli Oilfield in Dongying city of Shandong Province, an experiment was designed to study the characteristics and mechanism of thermal infrared emissivity spectrum of artificial crude oil slick covered seawater surface with its thickness. During the experiment, crude oil was continuously dropped into the seawater to generate artificial oil slick with different thicknesses. By adding each drop of crude oil, we measured the reflectivity of the oil slick in the thermal infrared spectrum with the Fourier transform infrared spectrometer (102F) and then calculated its thermal infrared emissivity. The results show that the thermal infrared emissivity of oil slick changes significantly with its thickness when oil slick is relatively thin (20-120 μm), which provides an effective means for detecting the existence of offshore thin oil slick In the spectrum ranges from 8 to 10 μm and from 13. 2 to 14 μm, there is a steady emissivity difference between the seawater and thin oil slick with thickness of 20 μm. The emissivity of oil slick changes marginally with oil slick thickness and

  2. The effect of ROCK-1 activity change on the adhesive and invasive ability of Y79 retinoblastoma cells

    International Nuclear Information System (INIS)

    Retinoblastoma (Rb) is the most common intraocular tumor in childhood worldwide. It is a deadly pediatric eye cancer. The main cause of death in Rb patients is intracranial and systemic metastasis. ROCK is the main downstream effector of Ras-homologous (Rho) family of GTPases which are involved in many cellular functions, such as cell proliferation, invasion and metastasis. Overexpression of ROCK promotes invasion and metastasis of many solid tumors. However, the effect of ROCK in Rb is largely unknown. ROCK-1 and ROCK-2 mRNA expression in Y79 cell lines were examined by RT-PCR. Protein expression in the Y79 cell line were examined by western blot analyses. ROCK-1 and ROCK-2 siRNA were transfected into Y79 cells with Lipofectamine 2000. Cell proliferation was evaluated by CCK-8 assay after exposure to ROCK inhibitor (Y-27632). We examined the effect of ROCK inhibitors (Y-27632, ROCK-1 and ROCK-2 siRNA) on Y79 cell adhesive capacity by cell adhesion assay. Cell invasion assay through matrigel was used to study the effect of ROCK inhibitors on Y79 cell invasive capacity. The expression of mRNA of ROCK-1 was more than that of ROCK-2 in the Y79 cell line. The protein expression levels of ROCK-1 and ROCK-2 were downregulated in the cells transfected with siRNA. Y-27632 treatment didn’t lead to any changes of Y79 cells proliferation. Adhesive ability of Y79 cells was enhanced following Y-27632 or ROCK-1 siRNA treatment. The invasive capacity of Y79 cells showed an inverse relationship with increasing Y-27632 concentration. Invasiveness of Y79 cells also decreased in Y79 cells transfected with ROCK-1 siRNA. However, there was no change in adhesive ability or invasive capacity in Y79 cells transfected with siRNA against ROCK-2. The findings of this study demonstrate that ROCK-1 protein plays a key role in regulating metastasis and invasion of Y79 cells, suggesting that the ROCK-1 dependent pathway may be a potential target for therapy of Rb

  3. Natural oil slicks in the Gulf of Mexico visible from space

    Science.gov (United States)

    MacDonald, I. R.; Guinasso, N. L.; Ackleson, S. G.; Amos, J. F.; Duckworth, R.; Sassen, R.; Brooks, J. M.

    1993-01-01

    Natural oil seepage in the Gulf of Mexico causes persistent surface slicks that are visible from space in predictable locations. A photograph of the sun glint pattern offshore from Louisiana taken from the space shuttle Atlantis on May 5, 1989, shows at least 124 slicks in an area of about 15,000 km2; a thematic mapper (TM) image collected by the Landsat orbiter on July 31, 1991, shows at least 66 slicks in a cloud-free area of 8200 km2 that overlaps the area of the photograph. Samples and descriptions made from a surface ship, from aircraft, and from a submarine confirmed the presence of crude oil in floating slicks. The imagery data show surface slicks near eight locations where chemosynthetic communities dependent upon seeping hydrocarbons are known to occur on the seafloor. Additionally, a large surface slick above the location of an active mud volcano was evident in the TM image. In one location the combined set of observations confirmed the presence of a flourishing chemosynthetic community, active seafloor oil and gas seepage, crude oil on the sea surface, and slick features that were visible in both images. We derived an analytical expression for the formation of floating slicks based on a parameterization of seafloor flow rate, downstream movement on the surface, half-life of floating oil, and threshold thickness for detection. Applying this equation to the lengths of observed slicks suggested that the slicks in the Atlantis photograph and in the TM image represent seepage rates of 2.2-30 m3 1000 km-2 d-1 and 1.4-18 m3 1000 km-2 d-1, respectively. Generalizing to an annual rate suggests that total natural seepage in this region is of the order of at least 20,000 m3 yr-1 (120,000 barrels yr-1).

  4. Natural oil slicks fuel surface water microbial activities in the northern Gulf of Mexico.

    Science.gov (United States)

    Ziervogel, Kai; D'Souza, Nigel; Sweet, Julia; Yan, Beizhan; Passow, Uta

    2014-01-01

    We conducted a series of roller tank incubations with surface seawater from the Green Canyon oil reservoir, northern Gulf of Mexico, amended with either a natural oil slick (GCS-oil) or pristine oil. The goal was to test whether bacterial activities of natural surface water communities facilitate the formation of oil-rich marine snow (oil snow). Although oil snow did not form during any of our experiments, we found specific bacterial metabolic responses to the addition of GCS-oil that profoundly affected carbon cycling within our 4-days incubations. Peptidase and β-glucosidase activities indicative of bacterial enzymatic hydrolysis of peptides and carbohydrates, respectively, were suppressed upon the addition of GCS-oil relative to the non-oil treatment, suggesting that ascending oil and gas initially inhibits bacterial metabolism in surface water. Biodegradation of physically dispersed GCS-oil components, indicated by the degradation of lower molecular weight n-alkanes as well as the rapid transformation of particulate oil-carbon (C: N >40) into the DOC pool, led to the production of carbohydrate- and peptide-rich degradation byproducts and bacterial metabolites such as transparent exopolymer particles (TEP). TEP formation was highest at day 4 in the presence of GCS-oil; in contrast, TEP levels in the non-oil treatment already peaked at day 2. Cell-specific enzymatic activities closely followed TEP concentrations in the presence and absence of GCS-oil. These results demonstrate that the formation of oil slicks and activities of oil-degrading bacteria result in a temporal offset of microbial cycling of organic matter, affecting food web interactions and carbon cycling in surface waters over cold seeps.

  5. Natural oil slicks fuel surface water microbial activities in the northern Gulf of Mexico

    Directory of Open Access Journals (Sweden)

    Kai eZiervogel

    2014-05-01

    Full Text Available We conducted a series of roller tank incubations with surface seawater from the Green Canyon oil reservoir, northern Gulf of Mexico, amended with either a natural oil slick (GCS-oil or pristine oil. The goal was to test whether bacterial activities of natural surface water communities facilitate the formation of oil-rich marine snow (oil snow. Although oil snow did not form during any of our experiments, we found specific bacterial metabolic responses to the addition of GCS-oil that profoundly affected carbon cycling within our 4-days incubations. Peptidase and -glucosidase activities indicative of bacterial enzymatic hydrolysis of peptides and carbohydrates, respectively, were suppressed upon the addition of GCS-oil relative to the non-oil treatment, suggesting that ascending oil and gas initially inhibits bacterial metabolism in surface water. Biodegradation of physically dispersed GCS-oil components indicated by the degradation of lower molecular weight n-alkanes as well as the rapid transformation of particulate oil-carbon (C: N >40 into the DOC pool, led to the production of carbohydrate- and peptide-rich degradation byproducts and bacterial metabolites such as transparent exopolymer particles (TEP. TEP formation was highest at day 4 in the presence of GCS-oil; in contrast, TEP levels in the non-oil treatment already peaked at day 2. Cell-specific enzymatic activities closely followed TEP concentrations in the presence and absence of GCS-oil. These results demonstrate that the formation of oil slicks and activities of oil-degrading bacteria result in a temporal offset of microbial cycling of organic matter, affecting food web interactions and carbon cycling in surface waters over cold seeps.

  6. ROCK inhibition enhances neurite outgrowth in neural stem cells by upregulating YAP expressionin vitro

    Institute of Scientific and Technical Information of China (English)

    Xu-feng Jia; Fei Ye; Yan-bo Wang; Da-xiong Feng

    2016-01-01

    Spontaneous axonal regeneration of neurons does not occur after spinal cord injury because of inhibition by myelin and other inhibitory factors. Studies have demonstrated that blocking the Rho/Rho-kinase (ROCK) pathway can promote neurite outgrowth in spinal cord injury models. In the present study, we investigated neurite outgrowth and neuronal differentiation in neural stem cells from the mouse subventricular zone after inhibition of ROCK in vitro. Inhibition of ROCK with Y-27632 increased neurite length, enhanced neuronal differentiation, and upregulated the expression of two major signaling pathway effectors, phospho-Akt and phospho-mitogen-activated protein kinase, and the Hippo pathway effector YAP. These results suggest that inhibition of ROCK mediates neurite outgrowth in neural stem cells by activating the Hippo signaling pathway.

  7. ROCK inhibition enhances neurite outgrowth in neural stem cells by upregulating YAP expression in vitro

    Science.gov (United States)

    Jia, Xu-feng; Ye, Fei; Wang, Yan-bo; Feng, Da-xiong

    2016-01-01

    Spontaneous axonal regeneration of neurons does not occur after spinal cord injury because of inhibition by myelin and other inhibitory factors. Studies have demonstrated that blocking the Rho/Rho-kinase (ROCK) pathway can promote neurite outgrowth in spinal cord injury models. In the present study, we investigated neurite outgrowth and neuronal differentiation in neural stem cells from the mouse subventricular zone after inhibition of ROCK in vitro. Inhibition of ROCK with Y-27632 increased neurite length, enhanced neuronal differentiation, and upregulated the expression of two major signaling pathway effectors, phospho-Akt and phospho-mitogen-activated protein kinase, and the Hippo pathway effector YAP. These results suggest that inhibition of ROCK mediates neurite outgrowth in neural stem cells by activating the Hippo signaling pathway. PMID:27482229

  8. The feasibility of pneumatic and water spray barriers as fireproof oil slick containment devices

    Energy Technology Data Exchange (ETDEWEB)

    Comfort, G.; Menon, B.; Purves, W.

    An Artec Canada, Ltd., project assessed the feasibility of using submerged pneumatic barriers and elevated water spray barriers to retain and concentrate a floating oil slick. Maximum wave, wind, and current conditions at which the barriers were able to operate as oil slick containment devices were measured. Various fluid flow rates and barrier configurations were tested. An examination of data and available literature indicate that, in terms of oil slick containment, the water spray barrier is superior to the pneumatic barrier. The construction and field testing of a prototype water spray barrier system should be initiated. (2 diagrams, 7 graphs, 3 tables)

  9. Critical role of exogenous nitric oxide in ROCK activity in vascular smooth muscle cells.

    Directory of Open Access Journals (Sweden)

    Tatsuya Maruhashi

    Full Text Available Rho-associated kinase (ROCK signaling pathway has been shown to mediate various cellular functions including cell proliferation, migration, adhesion, apoptosis, and contraction, all of which may be involved in pathogenesis of atherosclerosis. Endogenous nitric oxide (NO is well known to have an anti-atherosclerotic effect, whereas the exogenous NO-mediated cardiovascular effect still remains controversial. The purpose of this study was to evaluate the effect of exogenous NO on ROCK activity in vascular smooth muscle cells (VSMCs in vitro and in vivo.VSMCs migration was evaluated using a modified Boyden chamber assay. ROCK activities were measured by Western blot analysis in murine and human VSMCs and aorta of mice treated with or without angiotensin II (Ang II and/or sodium nitroprusside (SNP, an NO donor.Co-treatment with SNP inhibited the Ang II-induced cell migration and increases in ROCK activity in murine and human VSMCs. Similarly, the increased ROCK activity 2 weeks after Ang II infusion in the mouse aorta was substantially inhibited by subcutaneous injection of SNP.These findings suggest that administration of exogenous NO can inhibit ROCK activity in VSMCs in vitro and in vivo.

  10. Inhibitors of Rho kinase (ROCK) signaling revert the malignant phenotype of breast cancer cells in 3D context.

    Science.gov (United States)

    Matsubara, Masahiro; Bissell, Mina J

    2016-05-31

    Loss of polarity and quiescence along with increased cellular invasiveness are associated with breast tumor progression. ROCK plays a central role in actin-cytoskeletal rearrangement. We used physiologically relevant 3D cultures of nonmalignant and cancer cells in gels made of laminin-rich extracellular matrix, to investigate ROCK function. Whereas expression levels of ROCK1 and ROCK2 were elevated in cancer cells compared to nonmalignant cells, this was not observed in 2D cultures. Malignant cells showed increased phosphorylation of MLC, corresponding to disorganized F-actin. Inhibition of ROCK signaling restored polarity, decreased disorganization of F-actin, and led to reduction of proliferation. Inhibition of ROCK also decreased EGFR and Integrinβ1 levels, and consequently suppressed activation of Akt, MAPK and FAK as well as GLUT3 and LDHA levels. Again, ROCK inhibition did not inhibit these molecules in 2D. A triple negative breast cancer cell line, which lacks E-cadherin, had high levels of ROCK but was less sensitive to ROCK inhibitors. Exogenous overexpression of E-cadherin, however, rendered these cells strikingly sensitive to ROCK inhibition. Our results add to the growing literature that demonstrate the importance of context and tissue architecture in determining not only regulation of normal and malignant phenotypes but also drug response.

  11. Biological energy from the igneous rock enhances cell growth and enzyme activity

    Energy Technology Data Exchange (ETDEWEB)

    Lin Y.-L. E-mail: yllin@tmc.edu.tw; Kuo, H.-S; Chen, C.-T.; Kuo, S.-C

    2000-06-01

    Some effects from natural resources might be ignored and unused by humans. Environmental hormesis could be a phenomena necessary to bio-organism existence on earth. Since 1919, radiation and some heavy metal hormesis from the environment were proved in various reports. In this study, igneous rock with very low radioactivity and high ferrous activity was measured by multichannel analyzer and inductively coupled plasma analyzer. The water treated by igneous rock, both directly soaked or indirectly in contact, induced increased activities of glucose oxidase, catalase, peroxidase, and superoxide dismutase. It also increased cell growth of SC-M1, HCT-15, Raji, and fibroblast cell lines. The water after treatment of igneous rock had no change in pH values, but displayed decreased conductivity values. We assume that the igneous rock could transfer energy to water to change the molecular structure or conformation of water cluster, or by radiation hormesis effect could then induce increased enzyme activity and cell growth. It is also possible that the energy from rock may combine radiation hormesis with other transferable biological energy forms to change water cluster conformation.

  12. Cancer Stem Cells and Radioresistance: Rho/ROCK Pathway Plea Attention

    Science.gov (United States)

    Pranatharthi, Annapurna; Ross, Cecil

    2016-01-01

    Radiation is the most potent mode of cancer therapy; however, resistance to radiation therapy results in tumor relapse and subsequent fatality. The cancer stem cell (CSC), which has better DNA repair capability, has been shown to contribute to tumor resistance and is an important target for treatment. Signaling molecules such as Notch, Wnt, and DNA repair pathways regulate molecular mechanisms in CSCs; however, none of them have been translated into therapeutic targets. The RhoGTPases and their effector ROCK-signaling pathway, though important for tumor progression, have not been well studied in the context of radioresistance. There are reports that implicate RhoA in radioresistance. ROCK2 has also been shown to interact with BRCA2 in the regulation of cell division. Incidentally, statins (drug for cardiovascular ailment) are functional inhibitors of RhoGTPases. Studies suggest that patients on statins have a better prognosis in cancers. Data from our lab suggest that ROCK signaling regulates radioresistance in cervical cancer cells. Collectively, these findings suggest that Rho/ROCK signaling may be important for radiation resistance. In this review, we enumerate the role of Rho/ROCK signaling in stemness and radioresistance and highlight the need to explore these molecules for a better understanding of radioresistance and development of therapeutics. PMID:27597870

  13. Mississippi River and sea surface height effects on oil slick migration.

    Science.gov (United States)

    Falcini, Frederico; Jerolmack, Douglas J; Nardelli, Bruno Buongiorno

    2012-01-01

    Millions of barrels of oil escaped into the Gulf of Mexico (GoM) after the 20 April, 2010 explosion of Deepwater Horizon (DH). Ocean circulation models were used to forecast oil slick migration in the GoM, however such models do not explicitly treat the effects of secondary eddy-slopes or Mississippi River (MR) hydrodynamics. Here we report oil front migration that appears to be driven by sea surface level (SSL) slopes, and identify a previously unreported effect of the MR plume: under conditions of relatively high river discharge and weak winds, a freshwater mound can form around the MR Delta. We performed temporal oil slick position and altimeter analysis, employing both interpolated altimetry data and along-track measurements for coastal applications. The observed freshwater mound appears to have pushed the DH oil slick seaward from the Delta coastline. We provide a physical mechanism for this novel effect of the MR, using a two-layer pressure-driven flow model. Results show how SSL variations can drive a cross-slope migration of surface oil slicks that may reach velocities of order km/day, and confirm a lag time of order 5-10 days between mound formation and slick migration, as observed form the satellite analysis. Incorporating these effects into more complex ocean models will improve forecasts of slick migration for future spills. More generally, large SSL variations at the MR mouth may also affect the dispersal of freshwater, nutrients and sediment associated with the MR plume. PMID:22558317

  14. Mississippi River and Sea Surface Height Effects on Oil Slick Migration

    Science.gov (United States)

    Falcini, Frederico; Jerolmack, Douglas J.; Buongiorno Nardelli, Bruno

    2012-01-01

    Millions of barrels of oil escaped into the Gulf of Mexico (GoM) after the 20 April, 2010 explosion of Deepwater Horizon (DH). Ocean circulation models were used to forecast oil slick migration in the GoM, however such models do not explicitly treat the effects of secondary eddy-slopes or Mississippi River (MR) hydrodynamics. Here we report oil front migration that appears to be driven by sea surface level (SSL) slopes, and identify a previously unreported effect of the MR plume: under conditions of relatively high river discharge and weak winds, a freshwater mound can form around the MR Delta. We performed temporal oil slick position and altimeter analysis, employing both interpolated altimetry data and along-track measurements for coastal applications. The observed freshwater mound appears to have pushed the DH oil slick seaward from the Delta coastline. We provide a physical mechanism for this novel effect of the MR, using a two-layer pressure-driven flow model. Results show how SSL variations can drive a cross-slope migration of surface oil slicks that may reach velocities of order km/day, and confirm a lag time of order 5–10 days between mound formation and slick migration, as observed form the satellite analysis. Incorporating these effects into more complex ocean models will improve forecasts of slick migration for future spills. More generally, large SSL variations at the MR mouth may also affect the dispersal of freshwater, nutrients and sediment associated with the MR plume. PMID:22558317

  15. Genome-wide association study and ancestral origins of the slick-hair coat in tropically adapted cattle.

    Science.gov (United States)

    Huson, Heather J; Kim, Eui-Soo; Godfrey, Robert W; Olson, Timothy A; McClure, Matthew C; Chase, Chad C; Rizzi, Rita; O'Brien, Ana M P; Van Tassell, Curt P; Garcia, José F; Sonstegard, Tad S

    2014-01-01

    The slick hair coat (SLICK) is a dominantly inherited trait typically associated with tropically adapted cattle that are from Criollo descent through Spanish colonization of cattle into the New World. The trait is of interest relative to climate change, due to its association with improved thermo-tolerance and subsequent increased productivity. Previous studies localized the SLICK locus to a 4 cM region on chromosome (BTA) 20 and identified signatures of selection in this region derived from Senepol cattle. The current study compares three slick-haired Criollo-derived breeds including Senepol, Carora, and Romosinuano and three additional slick-haired cross-bred lineages to non-slick ancestral breeds. Genome-wide association (GWA), haplotype analysis, signatures of selection, runs of homozygosity (ROH), and identity by state (IBS) calculations were used to identify a 0.8 Mb (37.7-38.5 Mb) consensus region for the SLICK locus on BTA20 in which contains SKP2 and SPEF2 as possible candidate genes. Three specific haplotype patterns are identified in slick individuals, all with zero frequency in non-slick individuals. Admixture analysis identified common genetic patterns between the three slick breeds at the SLICK locus. Principal component analysis (PCA) and admixture results show Senepol and Romosinuano sharing a higher degree of genetic similarity to one another with a much lesser degree of similarity to Carora. Variation in GWA, haplotype analysis, and IBS calculations with accompanying population structure information supports potentially two mutations, one common to Senepol and Romosinuano and another in Carora, effecting genes contained within our refined location for the SLICK locus.

  16. Genome-wide association study and ancestral origins of the slick-hair coat in tropically adapted cattle

    Directory of Open Access Journals (Sweden)

    Heather Jay Huson

    2014-04-01

    Full Text Available The slick hair coat (SLICK is a dominantly inherited trait typically associated with tropically adapted cattle that are from Criollo descent through Spanish colonization of cattle into the New World. The trait is of interest relative to climate change, due to its association with improved thermo-tolerance and subsequent increased productivity. Previous studies localized the SLICK locus to a 4 cM region on chromosome (Chr 20 and identified signatures of selection in this region derived from Senepol cattle. The current study compares three slick-haired Criollo-derived breeds including Senepol, Carora, and Romosinuano and three additional slick-haired cross-bred lineages to non-slick ancestral breeds. Genome-wide association (GWA, haplotype analysis, signatures of selection, runs of homozygosity, and identity by state (IBS calculations were used to identify a 0.8Mb (37.7-38.5Mb consensus region for the SLICK locus on Chr 20 in which contains SKP2 and SPEF2 as possible candidate genes. Three specific haplotype patterns are identified in slick individuals, all with zero frequency in non-slick individuals. Admixture analysis identified common genetic patterns between the three slick breeds at the SLICK locus. Principle component analysis and admixture results show Senepol and Romosinuano sharing a higher degree of genetic similarity to one another with a much lesser degree of similarity to Carora. Variation in GWA, haplotype analysis, and IBS calculations with accompanying population structure information supports potentially two mutations, one common to Senepol and Romosinuano and another in Carora, effecting genes contained within our refined location for the SLICK locus.

  17. Microrheology and ROCK signaling of human endothelial cells embedded in a 3D matrix.

    Science.gov (United States)

    Panorchan, Porntula; Lee, Jerry S H; Kole, Thomas P; Tseng, Yiider; Wirtz, Denis

    2006-11-01

    Cell function is profoundly affected by the geometry of the extracellular environment confining the cell. Whether and how cells plated on a two-dimensional matrix or embedded in a three-dimensional (3D) matrix mechanically sense the dimensionality of their environment is mostly unknown, partly because individual cells in an extended matrix are inaccessible to conventional cell-mechanics probes. Here we develop a functional assay based on multiple particle tracking microrheology coupled with ballistic injection of nanoparticles to measure the local intracellular micromechanical properties of individual cells embedded inside a matrix. With our novel assay, we probe the mechanical properties of the cytoplasm of individual human umbilical vein endothelial cells (HUVECs) embedded in a 3D peptide hydrogel in the presence or absence of vascular endothelial growth factor (VEGF). We found that VEGF treatment, which enhances endothelial migration, increases the compliance and reduces the elasticity of the cytoplasm of HUVECs in a matrix. This VEGF-induced softening response of the cytoplasm is abrogated by specific Rho-kinase (ROCK) inhibition. These results establish combined particle-tracking microrheology and ballistic injection as the first method able to probe the micromechanical properties and mechanical response to agonists and/or drug treatments of individual cells inside a matrix. These results suggest that ROCK plays an essential role in the regulation of the intracellular mechanical response to VEGF of endothelial cells in a 3D matrix.

  18. Ocean surface slick characterization by multi-polarization Radarsat-2 data

    Science.gov (United States)

    Skrunes, Stine; Brekke, Camilla; Eltoft, Torbjørn

    2012-09-01

    Marine oil spills are an important environmental problem, and satellite SAR remote sensing have become a valuable tool for the detection and monitoring of these spills. Natural phenomena with similar appearance as oil in SAR images, producing false detections, compose a challenge for oil spill observation services. One such lookalike phenomena is biogenic slicks produced by marine organisms. In this study we evaluate multi-polarization features for oil spill characterization and oil versus biogenic slick discrimination. During large-scale oil-on-water exercises conducted in the North Sea in June 2011 and June 2012, both mineral oil and plant oil were released and imaged by Radarsat-2 in Fine Quad-polarization mode. The plant oil will form a lm resembling biogenic slicks. The mineral oil spill and simulated look-alike are in this study compared based on multi-polarization features, combining the information in HH and VV channels. The polarimetric measurements from 2011 have earlier been analysed, and a potential for discrimination between mineral oil and biogenic slicks is found. The aim of the current study is to repeat the polarimetric analysis on the new independent data set from 2012. Preliminary results of the 2012 data set reveal both internal and between slick type variations, giving support to our previous findings from 2011.

  19. PEG-PEI/siROCK2 Protects Against Aβ42-Induced Neurotoxicity in Primary Neuron Cells for Alzheimer Disease.

    Science.gov (United States)

    Liu, Yunyun; Yang, Xingyi; Lei, Qingfeng; Li, Zhong; Hu, Jingyang; Wen, Xiaojun; Wang, Huijun; Liu, Zhonglin

    2015-08-01

    Gene therapy that targets the ROCK2 gene has yielded promising results in the treatment of AD. Our previous study indicated that PEG-PEI/siROCK2 could effectively suppress ROCK2 mRNA expression and showed a promising prospect for the treatment of Alzheimer's disease. However, the ability of PEG-PEI/siROCK2 to reduce Aβ-induced cytotoxicity is unknown. To investigate the effect of PEG-PEI/siROCK2 against Aβ42-induced neurotoxicity, primary cultured cortical neurons were pretreated with PEG-PEI/siROCK2 for 24 h and then treated with 5 μM Aβ42 for 24 h. We found that PEG-PEI/siROCK2 increased the cell viability and reduced the number of apoptotic cells induced by Aβ42, as measured using an MTT assay and Annexin V/PI staining. A further study revealed that PEG-PEI/siROCK2 can activate p-Akt, and treatment with the PI3K inhibitor LY294002 attenuated the neuroprotective effects. These results suggest that PEG-PEI/siROCK2 prevents Aβ42-induced neurotoxicity and that the activation of PI3K/Akt pathway is involved in neuroprotection. Taken together, these findings shed light on the role of PEG-PEI/siROCK2 as a potential therapeutic agent for AD.

  20. Numerical simulation of interactions of the oil slick and currents under ice cover

    Energy Technology Data Exchange (ETDEWEB)

    Matsuzaki, Y. [Port and Airport Research Inst., Yokosuka, Kanagawa (Japan); Sakai, S. [Iwate Univ., Morioka, Iwate (Japan)

    2008-07-01

    If an oil spill should occur offshore Sakhalin Island where oil and gas operations have recently started, the coastal area along the Sea of Okhotsk in Hokkaido Japan would be at risk of serious environmental damage because of the strong southward ocean current. In addition, it would be impossible to find the spilled oil in winter when the sea surface area is covered by ice. This paper presented a study in which a numerical simulation was developed to treat the interactions of oil slicks and currents. The simulation method simulated experimental results of the deformation and movement of an oil slick under ice cover and ice bottom configurations. It was shown that the characteristics of the deformation and movement of the oil slick by currents under the ice depend on the properties of the oil, such as density, the oil-water interfacial tension, and viscosity. 3 refs., 1 tab., 9 figs.

  1. Mississippi River and sea surface height effects on oil slick migration.

    Directory of Open Access Journals (Sweden)

    Frederico Falcini

    Full Text Available Millions of barrels of oil escaped into the Gulf of Mexico (GoM after the 20 April, 2010 explosion of Deepwater Horizon (DH. Ocean circulation models were used to forecast oil slick migration in the GoM, however such models do not explicitly treat the effects of secondary eddy-slopes or Mississippi River (MR hydrodynamics. Here we report oil front migration that appears to be driven by sea surface level (SSL slopes, and identify a previously unreported effect of the MR plume: under conditions of relatively high river discharge and weak winds, a freshwater mound can form around the MR Delta. We performed temporal oil slick position and altimeter analysis, employing both interpolated altimetry data and along-track measurements for coastal applications. The observed freshwater mound appears to have pushed the DH oil slick seaward from the Delta coastline. We provide a physical mechanism for this novel effect of the MR, using a two-layer pressure-driven flow model. Results show how SSL variations can drive a cross-slope migration of surface oil slicks that may reach velocities of order km/day, and confirm a lag time of order 5-10 days between mound formation and slick migration, as observed form the satellite analysis. Incorporating these effects into more complex ocean models will improve forecasts of slick migration for future spills. More generally, large SSL variations at the MR mouth may also affect the dispersal of freshwater, nutrients and sediment associated with the MR plume.

  2. Primordial oil slick and the formation of hydrophobic tetrapyrrole macrocycles.

    Science.gov (United States)

    Soares, Ana R M; Taniguchi, Masahiko; Chandrashaker, Vanampally; Lindsey, Jonathan S

    2012-11-01

    The functional end products of the extant biosynthesis of tetrapyrrole macrocycles in photosynthetic organisms are hydrophobic: chlorophylls and bacteriochlorophylls. A model for the possible prebiogenesis of hydrophobic analogues of nature's photosynthetic pigments was investigated by reaction of acyclic reactants in five media: aqueous solution (pH 7, 60°C, 24 h); aqueous solution containing 0.1 M decanoic acid (which forms a turbid suspension of vesicles); or aqueous solution accompanied by dodecane, mesitylene, or a five-component organic mixture (each of which forms a phase-separated organic layer). The organic mixture was composed of equimolar quantities of decanoic acid, dodecane, mesitylene, naphthalene, and pentyl acetate. The reaction of 1,5-dimethoxy-3-methylpentan-2,4-dione and 1-aminobutan-2-one to give etioporphyrinogens was enhanced in the presence of decanoic acid, affording (following chemical oxidation) etioporphyrins (tetraethyltetramethylporphyrins) in yields of 1.4-10.8% across the concentration range of 3.75-120 mM. The yield of etioporphyrins was greater in the presence of the five-component organic mixture (6.6% at 120 mM) versus that with dodecane or mesitylene (2.1% or 2.9%, respectively). The reaction in aqueous solution with no added oil-slick constituents resulted in phase separation-where the organic reactants themselves form an upper organic layer-and the yield of etioporphyrins was 0.5-2.6%. Analogous reactions leading to uroporphyrins (hydrophilic, eight carboxylic acids) or coproporphyrins (four carboxylic acids) were unaffected by the presence of decanoic acid or dodecane, and all yields were at most ∼2% or ∼8%, respectively. Taken together, the results indicate a facile means for the formation of highly hydrophobic constituents of potential value for prebiotic photosynthesis. PMID:23095096

  3. Effects of artificial sea film slick upon the atmospheric boundary layer structure

    Science.gov (United States)

    Repina, Irina; Artamonov, Arseniy; Malinovsky, Vladimir; Chechin, Dmitriy

    2010-05-01

    Organic surface-active compounds accumulate at the ocean-atmosphere boundary, influencing several air-sea interaction processes. In coastal areas with high biological activity this accumulation frequently becomes visible as mirrorlike patches ("slicks") on the sea surface. The artificial surface films of oleyl alcohol and vegetable oil were produced in the Black Sea coastal zone (one site was located near Gelendjik and another was near Crimea coast) to investigate its influence on energy and gas exchange between atmosphere and sea surface under different meteorological conditions. The atmospheric turbulence measurements during the passage of an artificial sea slick are compared with similar measurements without a sea slick. The effects of the slick are modifications of roughness length z0, and a possible increase in mean wind speed. In the mean, during the passage of the slick, the roughness length decreased while the mean wind speed appeared to increase. For the spectral comparison we compared the wind field over the sea during the time the film slick was in the vicinity of the measurement site with the wind field observed after the slick had passed. The cross-spectral density was computed between horizontal velocity and vertical velocity (Reynolds stress) and between atmospheric temperature and vertical velocity (heat flux). The introduction of the sea film slick, with its damping and suppression of capillary waves, appears to completely destroy the atmospheric turbulence generation. When a slick is present, the U-W phase angle and Reynolds stress spectrum for the atmosphere appear to be completely unaffected by undulating sea surface directly below the sensors. Spectral and wavelet analysis of the atmospheric surface layer characteristics showed a significant correlation between the processes on the sea surface and the atmospheric boundary layer. An intensification of change processes in the vicinity of the windward slick boundary are detected. It may be

  4. ROCK activity affects IL-1-induced signaling possibly through MKK4 and p38 MAPK in Caco-2 cells.

    Science.gov (United States)

    Banerjee, Sayantan; McGee, Dennis W

    2016-09-01

    Elevated levels of interleukin-1 (IL-1) accompany inflammatory bowel disease. IL-1-stimulated intestinal epithelial cells can secrete potent chemokines like CXCL8 to exacerbate inflammation. Previously, we found that inhibiting the Rho-associated kinase (ROCK) could inhibit IL-1- or TNF-α-induced CXCL8 secretion by the Caco-2 colonic epithelial cell line. This ROCK inhibition did not affect IκBα phosphorylation and degradation, but suppressed the phosphorylation of c-Jun N-terminal kinase (JNK). Therefore, ROCK must play an important role in epithelial cell CXCL8 responses through an effect on the JNK signaling pathway. Here, we extend these studies by showing that inhibiting ROCK suppressed the IL-1-induced phosphorylation of MKK4, a known activator of JNK, but not MKK7. Yet, ROCK inhibition had no significant effect on the IL-1-induced phosphorylation of extracellular-signal-regulated kinase (ERK) 1/2. Inhibiting ROCK also suppressed the phosphorylation of p38 MAPK after IL-1 stimulation, but this inhibition had no significant effect on the stability of CXCL8 messenger RNA (mRNA) after IL-1 stimulation. These results suggest that ROCK may be important in IL-1-induced signaling through MKK4 to JNK and the activation of p38 MAPK. Finally, inhibiting ROCK in IL-1 and TNF-α co-stimulated Caco-2 cells also resulted in a significant suppression of CXCL8 secretion and mRNA levels suggesting that inhibiting ROCK may be a mechanism to inhibit the overall response of epithelial cells to both cytokines. These studies indicate a novel signaling event, which could provide a target for suppressing intestinal epithelial cells (IEC) chemokine responses involved in mucosal inflammation. PMID:27173611

  5. Rho-associated kinase (ROCK) inhibition reverses low cell activity on hydrophobic surfaces

    International Nuclear Information System (INIS)

    Hydrophobic polymers do not offer an adequate scaffold surface for cells to attach, migrate, proliferate, and differentiate. Thus, hydrophobic scaffolds for tissue engineering have traditionally been physicochemically modified to enhance cellular activity. However, modifying the surface by chemical or physical treatment requires supplementary engineering procedures. In the present study, regulation of a cell signal transduction pathway reversed the low cellular activity on a hydrophobic surface without surface modification. Inhibition of Rho-associated kinase (ROCK) by Y-27632 markedly enhanced adhesion, migration, and proliferation of osteoblastic cells cultured on a hydrophobic polystyrene surface. ROCK inhibition regulated cell-cycle-related molecules on the hydrophobic surface. This inhibition also decreased expression of the inhibitors of cyclin-dependent kinases such as p21cip1 and p27kip1 and increased expression of cyclin A and D. These results indicate that defective cellular activity on the hydrophobic surface can be reversed by the control of a cell signal transduction pathway without physicochemical surface modification.

  6. Downregulation of ROCK2 through nanocomplex sensitizes the cytotoxic effect of temozolomide in U251 glioma cells.

    Directory of Open Access Journals (Sweden)

    Xiaojun Wen

    Full Text Available OBJECTIVE: Rho-associated coiled-coil kinase 2 (ROCK2 is an attractive therapeutic target because it is overexpressed in many malignancies, including glioma. Therefore, we designed the current study to determine whether the downregulation of ROCK2 would sensitize the cytotoxic effect of temozolomide (TMZ in U251 cells. METHODS: Glycol-polyethyleneimine (PEG-PEI was used to deliver siROCK2 to U251 cells, and the physical characteristics of the PEG-PEI/siROCK2 complex (referred to as the siROCK2 complex were investigated. The transfection efficiency and cell uptake were determined by flow cytometry (FCM and confocal laser microscopy (CLSM, respectively. U251 cells were then treated with 100 μM TMZ, siROCK2 complexes or their combination. The apoptosis rate and cell migration were measured by FCM and wound-healing assay, respectively. The levels of Bax, Bcl-2, cleaved caspase-3, MMP-2, and MMP-9 were detected to analyze the degrees of apoptosis and migration. RESULTS: Our results revealed that the characteristics of the siROCK2 complexes depended closely on the N/P ratios. PEG-PEI served as a good vector for siROCK2 and exhibited low cytotoxicity toward U251 cells. The CLSM assay showed that the siROCK2 complexes were successfully uptaken and that both the protein and mRNA levels of ROCK2 were significantly suppressed. Furthermore, the combination treatment induced a higher apoptosis rate and markedly increased the gap distance of U251 cells in the wound-healing assay. Levels of the proapoptotic proteins Bax and cleaved caspase-3 were significantly increased, whereas levels of the antiapoptotic protein Bcl-2 and the migration-related proteins MMP-2 and MMP-9 were significantly reduced by the combination treatment compared with either treatment alone. CONCLUSIONS: In conclusion, our results demonstrate that the combination of TMZ and siROCK2 effectively induces apoptosis and inhibits the migration of U251 cells. Therefore, the combination of TMZ

  7. An assessment of plant biointrusion at the Uranium Mill Tailings Remedial Action Project rock-covered disposal cells

    Energy Technology Data Exchange (ETDEWEB)

    1990-10-01

    This study is one of a number of special studies that have been conducted regarding various aspects of the Uranium Mill Tailings Remedial Action (UMTRA) Project. This special study was proposed following routine surveillance and maintenance surveys and observations reported in a special study of vegetative covers (DOE, 1988), in which plants were observed growing up through the rock erosion layer at recently completed disposal cells. Some of the plants observed were deep-rooted woody species, and questions concerning root intrusion into disposal cells and the need to control plant growth were raised. The special study discussed in this report was designed to address some of the ramifications of plant growth on disposal cells that have rock covers. The NRC has chosen rock covers over vegetative covers in the arid western United States because licenses cannot substantiate that the vegetative covers will be significantly greater than 30 percent and preferably 70 percent,'' which is the amount of vegetation required to reduce flow to a point of stability.'' The potential impacts of vegetation growing in rock covers are not addressed by the NRC (1990). The objectives, then, of this study were to determine the species of plants growing on two rock-covered disposal cells, study the rooting pattern of plants on these cells, and identify possible impacts of plant root penetration on these and other UMTRA Project rock-covered cells.

  8. An assessment of plant biointrusion at the Uranium Mill Tailings Remedial Action Project rock-covered disposal cells

    International Nuclear Information System (INIS)

    This study is one of a number of special studies that have been conducted regarding various aspects of the Uranium Mill Tailings Remedial Action (UMTRA) Project. This special study was proposed following routine surveillance and maintenance surveys and observations reported in a special study of vegetative covers (DOE, 1988), in which plants were observed growing up through the rock erosion layer at recently completed disposal cells. Some of the plants observed were deep-rooted woody species, and questions concerning root intrusion into disposal cells and the need to control plant growth were raised. The special study discussed in this report was designed to address some of the ramifications of plant growth on disposal cells that have rock covers. The NRC has chosen rock covers over vegetative covers in the arid western United States because licenses cannot substantiate that the vegetative covers ''will be significantly greater than 30 percent and preferably 70 percent,'' which is the amount of ''vegetation required to reduce flow to a point of stability.'' The potential impacts of vegetation growing in rock covers are not addressed by the NRC (1990). The objectives, then, of this study were to determine the species of plants growing on two rock-covered disposal cells, study the rooting pattern of plants on these cells, and identify possible impacts of plant root penetration on these and other UMTRA Project rock-covered cells

  9. The slick hair coat locus maps to chromosome 20 in Senepol-derived cattle.

    Science.gov (United States)

    Mariasegaram, M; Chase, C C; Chaparro, J X; Olson, T A; Brenneman, R A; Niedz, R P

    2007-02-01

    The ability to maintain normal temperatures during heat stress is an important attribute for cattle in the subtropics and tropics. Previous studies have shown that Senepol cattle and their crosses with Holstein, Charolais and Angus animals are as heat tolerant as Brahman cattle. This has been attributed to the slick hair coat of Senepol cattle, which is thought to be controlled by a single dominant gene. In this study, a genome scan using a DNA-pooling strategy indicated that the slick locus is most likely on bovine chromosome 20 (BTA20). Interval mapping confirmed the BTA20 assignment and refined the location of the locus. In total, 14 microsatellite markers were individually genotyped in two pedigrees consisting of slick and normal-haired cattle (n = 36), representing both dairy and beef breeds. The maximum LOD score was 9.4 for a 4.4-cM support interval between markers DIK2416 and BM4107. By using additional microsatellite markers in this region, and genotyping in six more pedigrees (n = 86), the slick locus was further localized to the DIK4835 - DIK2930 interval. PMID:17257189

  10. Topography induces differential sensitivity on cancer cell proliferation via Rho-ROCK-Myosin contractility

    Science.gov (United States)

    Chaudhuri, Parthiv Kant; Pan, Catherine Qiurong; Low, Boon Chuan; Lim, Chwee Teck

    2016-01-01

    Although the role of stiffness on proliferative response of cancer cells has been well studied, little is known about the effect of topographic cues in guiding cancer cell proliferation. Here, we examined the effect of topographic cues on cancer cell proliferation using micron scale topographic features and observed that anisotropic features like microgratings at specific dimension could reduce proliferation of non-cancer breast epithelial cells (MCF-10A) but not that for malignant breast cancer cells (MDA-MB-231 and MCF-7). However, isotropic features such as micropillars did not affect proliferation of MCF-10A, indicating that the anisotropic environmental cues are essential for this process. Interestingly, acto-myosin contraction inhibitory drugs, Y-27632 and blebbistatin prevented micrograting-mediated inhibition on proliferation. Here, we propose the concept of Mechanically-Induced Dormancy (MID) where topographic cues could activate Rho-ROCK-Myosin signaling to suppress non-cancerous cells proliferation whereas malignant cells are resistant to this inhibitory barrier and therefore continue uncontrolled proliferation. PMID:26795068

  11. Rho Kinase ROCK2 Mediates Acid-Induced NADPH Oxidase NOX5-S Expression in Human Esophageal Adenocarcinoma Cells

    Science.gov (United States)

    Cao, Weibiao

    2016-01-01

    Mechanisms of the progression from Barrett’s esophagus (BE) to esophageal adenocarcinoma (EA) are not fully understood. We have shown that NOX5-S may be involved in this progression. However, how acid upregulates NOX5-S is not well known. We found that acid-induced increase in NOX5-S expression was significantly decreased by the Rho kinase (ROCK) inhibitor Y27632 in BE mucosal biopsies and FLO-1 EA cells. In addition, acid treatment significantly increased the Rho kinase activity in FLO-1 cells. The acid-induced increase in NOX5-S expression and H2O2 production was significantly decreased by knockdown of Rho kinase ROCK2, but not by knockdown of ROCK1. Conversely, the overexpression of the constitutively active ROCK2, but not the constitutively active ROCK1, significantly enhanced the NOX5-S expression and H2O2 production. Moreover, the acid-induced increase in Rho kinase activity and in NOX5-S mRNA expression was blocked by the removal of calcium in both FLO-1 and OE33 cells. The calcium ionophore A23187 significantly increased the Rho kinase activity and NOX5-S mRNA expression. We conclude that acid-induced increase in NOX5-S expression and H2O2 production may depend on the activation of ROCK2, but not ROCK1, in EA cells. The acid-induced activation of Rho kinase may be mediated by the intracellular calcium increase. It is possible that persistent acid reflux present in BE patients may increase the intracellular calcium, activate ROCK2 and thereby upregulate NOX5-S. High levels of reactive oxygen species derived from NOX5-S may cause DNA damage and thereby contribute to the progression from BE to EA. PMID:26901778

  12. Rho Kinase ROCK2 Mediates Acid-Induced NADPH Oxidase NOX5-S Expression in Human Esophageal Adenocarcinoma Cells.

    Directory of Open Access Journals (Sweden)

    Jie Hong

    Full Text Available Mechanisms of the progression from Barrett's esophagus (BE to esophageal adenocarcinoma (EA are not fully understood. We have shown that NOX5-S may be involved in this progression. However, how acid upregulates NOX5-S is not well known. We found that acid-induced increase in NOX5-S expression was significantly decreased by the Rho kinase (ROCK inhibitor Y27632 in BE mucosal biopsies and FLO-1 EA cells. In addition, acid treatment significantly increased the Rho kinase activity in FLO-1 cells. The acid-induced increase in NOX5-S expression and H2O2 production was significantly decreased by knockdown of Rho kinase ROCK2, but not by knockdown of ROCK1. Conversely, the overexpression of the constitutively active ROCK2, but not the constitutively active ROCK1, significantly enhanced the NOX5-S expression and H2O2 production. Moreover, the acid-induced increase in Rho kinase activity and in NOX5-S mRNA expression was blocked by the removal of calcium in both FLO-1 and OE33 cells. The calcium ionophore A23187 significantly increased the Rho kinase activity and NOX5-S mRNA expression. We conclude that acid-induced increase in NOX5-S expression and H2O2 production may depend on the activation of ROCK2, but not ROCK1, in EA cells. The acid-induced activation of Rho kinase may be mediated by the intracellular calcium increase. It is possible that persistent acid reflux present in BE patients may increase the intracellular calcium, activate ROCK2 and thereby upregulate NOX5-S. High levels of reactive oxygen species derived from NOX5-S may cause DNA damage and thereby contribute to the progression from BE to EA.

  13. Effects of ROCK inhibitor Y-27632 on cell fusion through a microslit.

    Science.gov (United States)

    Wada, Ken-Ichi; Hosokawa, Kazuo; Ito, Yoshihiro; Maeda, Mizuo

    2015-11-01

    We previously reported a direct cytoplasmic transfer method using a microfluidic device, in which cell fusion was induced through a microslit (slit-through-fusion) by the Sendai virus envelope (HVJ-E) to prevent nuclear mixing. However, the method was impractical due to low efficiency of slit-through-fusion formation and insufficient prevention of nuclear mixing. The purpose of this study was to establish an efficient method for inducing slit-through-fusion without nuclear mixing. We hypothesized that modulation of cytoskeletal component can decrease nuclear migration through the microslit considering its functions. Here we report that supplementation with Y-27632, a specific ROCK inhibitor, significantly enhances cell fusion induction and prevention of nuclear mixing. Supplementation with Y-27632 increased the formation of slit-through-fusion efficiency by more than twofold. Disruption of F-actin by Y-27632 prevented nuclear migration between fused cells through the microslit. These two effects of Y-27632 led to promotion of the slit-through-fusion without nuclear mixing with a 16.5-fold higher frequency compared to our previous method (i.e., cell fusion induction by HVJ-E without supplementation with Y-27632). We also confirmed that mitochondria were successfully transferred to the fusion partner under conditions of Y-27632 supplementation. These findings demonstrate the practicality of our cell fusion system in producing direct cytoplasmic transfer between live cells.

  14. On discrimination between film slicks and "look-alikes" on the sea surface in multifrequency radar images

    Science.gov (United States)

    Sergievskaya, Irina; Ermakov, Stanislav A.; Kapustin, Ivan

    2015-10-01

    Slicks on the sea surface are characterized by attenuation of short wind waves and appear in radar imagery at moderate incidence angles as areas of reduced intensity. In the proximity of oil platforms, ship routes, fish farms, etc. marine slicks are often identified as oil spills or biogenic films. However, probability of false alarm when detecting film slicks is very high because of the occurrence of structures in radar images looking similar but not related to surface films ("lookalikes"). One of the most frequent "look-alikes" is wind depression areas (WDAs) where the wind excitation of short surface waves is reduced compared to the ambient background. Results of field observations of films slicks and WDA are described and differences in character of wind wave attenuation in different parts of the wind wave spectrum are revealed. Model calculations of wave damping degree (contrast) in film slick and in WDA are carried out and are shown to be in general agreement with experiment. Capabilities of dual-polarization and multi-band microwave radar for discrimination between film slicks and "look-alikes" are analyzed based on experiment and model results.

  15. Critical study of the method of calculating virgin rock stresses from measurement results of the CSIR triaxial strain cell

    Science.gov (United States)

    Vreede, F. A.

    1981-05-01

    The manual of instructions for the user of the CSIR triaxial rock stress measuring equipment is critically examined. It is shown that the values of the rock stresses can be obtained from the strain gauge records by means of explicit formulae, which makes the manual's computer program obsolete. Furthermore statistical methods are proposed to check for faulty data and inhomogeneity in rock properties and virgin stress. The possibility of non-elastic behavior of the rock during the test is also checked. A new computer program based on the explicit functions and including the check calculations is presented. It is much more efficient than the one in the manual since it does not require computer sub-routines, allowing it to be used directly on any modern computer. The output of the new program is in a format suitable for direct inclusion in the report of an investigation using strain cell results.

  16. Enrichment of Fusobacteria in Sea Surface Oil Slicks from the Deepwater Horizon Oil Spill

    Science.gov (United States)

    Gutierrez, Tony; Berry, David; Teske, Andreas; Aitken, Michael D.

    2016-01-01

    The Deepwater Horizon (DWH) oil spill led to rapid microbial community shifts in the Gulf of Mexico, including the formation of unprecedented quantities of marine oil snow (MOS) and of a massive subsurface oil plume. The major taxa that bloomed in sea surface oil slicks during the spill included Cycloclasticus, and to a lesser extent Halomonas, Alteromonas, and Pseudoalteromonas—organisms that grow and degrade oil hydrocarbons aerobically. Here, we show that sea surface oil slicks at DWH contained obligate and facultative anaerobic taxa, including members of the obligate anaerobic phylum Fusobacteria that are commonly found in marine sediment environments. Pyrosequencing analysis revealed that Fusobacteria were strongly selected for when sea surface oil slicks were allowed to develop anaerobically. These organisms have been found in oil-contaminated sediments in the Gulf of Mexico, in deep marine oil reservoirs, and other oil-contaminated sites, suggesting they have putative hydrocarbon-degrading qualities. The occurrence and strong selection for Fusobacteria in a lab-based incubation of a sea surface oil slick sample collected during the spill suggests that these organisms may have become enriched in anaerobic zones of suspended particulates, such as MOS. Whilst the formation and rapid sinking of MOS is recognised as an important mechanism by which a proportion of the Macondo oil had been transported to the sea floor, its role in potentially transporting microorganisms, including oil-degraders, from the upper reaches of the water column to the seafloor should be considered. The presence of Fusobacteria on the sea surface—a highly oxygenated environment—is intriguing, and may be explained by the vertical upsurge of oil that provided a carrier to transport these organisms from anaerobic/micro-aerophilic zones in the oil plume or seabed to the upper reaches of the water column. We also propose that the formation of rapidly-sinking MOS may have re

  17. Refinement of the critical angle calculation for the contrast reversal of oil slicks under sunglint

    Science.gov (United States)

    Lu, Yingcheng; Sun, Shaojie; Zhang, Minwei; Murch, Brock; Hu, Chuanmin

    2016-01-01

    It has long been observed that oil slicks under sunglint can reverse their optical contrast against nearby oil-free seawater. Such a phenomenon has been described through both empirical statistical analysis of the sunglint strength and modeled theoretically using a critical angle concept. The critical angle, in this model, is the angle at which the image pixels show no or negligible contrast between oiled and nonoiled seawater. Pixels away from this critical angle show either positive or negative contrast from the oil-free pixels. Although this concept has been fully demonstrated in the published literature, its calculation needs to be further refined to take into account: (1) the different refractive indices of oil slicks (from natural seeps) and seawater and (2) atmospheric effects in the sensor-measured radiance. Using measurements from the Moderate Resolution Imaging Spectroradiometer (MODIS) over oil films in the Gulf of Mexico, we show improvement in the modeled and MODIS-derived reflectance over oil slicks originated from natural seeps after incorporating these two factors in the model. Specifically, agreement between modeled and measured sunglint reflectance is found for both negative and positive-contrasting oil slicks. These results indicate that surface roughness and reflectance from oil films can be estimated given any solar/viewing geometry and surface wind. Further, this model might be used to correct the sunglint effect on thick oil under similar illumination conditions. Once proven possible, it may allow existing laboratory-based models, which estimate oil thickness after such corrections, to be applied to remote sensing imagery.

  18. Comparing SAR measurments of natural oil seeps in the Gulf of Mexico with mineral and biological slicks in the North Sea

    OpenAIRE

    Hanssen, Claes Anders Storm

    2013-01-01

    In this thesis, natural oil seeps in Synthetic Aperture Radar (SAR) images are studied. The intension is to compare seeps to known oil slicks as emulsion-oil, crude-oil and plant-oil. TerraSAR-X and Radarsat-2 data with these di erent slicks are analyzed. Polarimetric features are extracted for all the scenes, histograms and scatterplots of values from the slicks are evaluated. Finally a classification is performed on images with slicks that are suspected to be seeps. Natural oil ...

  19. A Microscopic View of Oil Slick Break-Up and Emulsion Formation in Breaking Waves

    Science.gov (United States)

    Law, J.; Shahrokhi, H.; Shaw, J. M.

    1996-11-01

    The hydrodynamic behaviour of oil spills in breaking waves determines the appropriateness and effectiveness of remedial measures during clean-up operations. Oil slicks either disperse as fine drops or form water in oil emulsions when exposed to breaking waves. However, there is little agreement with respect to the controlling variables or mechanisms for emulsification or dispersion and predictions are unreliable. For example, predicted energy dissipation rates in breaking waves are too low to account for the drop sizes encountered experimentally[1]. In this paper, we assess the impact of hydrodynamics and physical properties on the formation of dispersions or emulsions. The maximum stable drop size for dispersions arising from oil slicks and water in oil emulsions are shown to be controlled by Raleigh-Taylor instability or the prevalent local shear stress. Data from four experimental studies[2-5], with a broad range of physical properties were fitted quantitatively. As high shear events are intermittent, stable water in oil emulsions can be formed by dispersion inversion near the water air interface or by water entrained by gas bubbles passing through oil slicks. 1) Li & Garrett, 19th AMOP, Calgary AB, 1, 185-198 (1996). 2) Lin et al., Report CG-D-54-78, U.S. Coast Guard, Washington D.C. (1978). 3) Buist, MASc Thesis, University of Toronto (1979). 4) Wallace et al., 9th AMOP, Edmonton AB, 2, 421-429, June 10-12 (1986). 5) Ross Environmental Research Ltd., Ottawa ON, Report EE-96, (1987).

  20. ROCK inhibitor fasudil attenuated high glucose-induced MCP-1 and VCAM-1 expression and monocyte-endothelial cell adhesion

    Directory of Open Access Journals (Sweden)

    Li Hailing

    2012-06-01

    Full Text Available Abstract Background Previous studies suggested that the RhoA/ROCK pathway may contribute to vascular complications in diabetes. The present study was designed to investigate whether ROCK inhibitor fasudil could prevent high glucose-induced monocyte-endothelial cells adhesion, and whether this was related to fasudil effects on vascular endothelial cell expression of chemotactic factors, vascular cell adhesion molecule-1 (VCAM-1 and monocyte chemoattractant protein-1 (MCP-1. Methods HUVECs were stimulated with high glucose (HG or HG + fasudil in different concentration or different time. Monocyte-endothelial cell adhesion was determined using fluorescence-labeled monocytes. The mRNA and protein expression of VCAM-1 and MCP-1 were measured using real-time PCR and western blot. The protein levels of RhoA, ROCKI and p-MYPT were determined using western blot analysis. ELISA was employed to measure the expression of soluble VCAM-1 and MCP-1 in cell supernatants and human serum samples. Results Fasudil significantly suppressed HG-induced adhesion of THP-1 to HUVECs. Fasudil reduced Rho/ROCK activity (as indicated by lower p-MYPT/MYPT ratio, and prevented HG induced increases in VCAM-1 and MCP-1 mRNA and protein levels. Fasudil also decreased MCP-1 concentration in HUVEC supernatants, but increased sVCAM-1 shedding into the media. In human diabetic subjects, 2 weeks of fasudil treatment significantly decreased serum MCP-1 level from 27.9 ± 10.6 pg/ml to 13.8 ± 7.0 pg/ml (P P  Conclusions Treatment with the Rho/ROCK pathway inhibitor fasudil attenuated HG-induced monocyte-endothelial cell adhesion, possibly by reducing endothelial expression of VCAM-1 and MCP-1. These results suggest inhibition of Rho/ROCK signaling may have therapeutic potential in preventing diabetes associated vascular inflammation and atherogenesis.

  1. See võid sina olla. See võib olla sinu kloon. Sina võid olla kloon / Gregory Slick ; interv. Eero Epner

    Index Scriptorium Estoniae

    Slick, Gregory

    2003-01-01

    USA fotograaf G. Slick, kellel lõppes residentuur EKL külalisateljees, endast, oma loomingust, Eestist jm. G. Slick jätkas Eestis tööd seeriatega "Natural Histories" ja "Humans vs Space". Intervjuu on antud "Vikerraadio" saate "Kultuurikaja" jaoks

  2. Interpreting sea surface slicks on the basis of the normalized radar cross-section model using RADARSAT-2 copolarization dual-channel SAR images

    Science.gov (United States)

    Ivonin, D. V.; Skrunes, S.; Brekke, C.; Ivanov, A. Yu.

    2016-03-01

    A simple automatic multipolarization technique for discrimination of main types of thin oil films (of thickness less than the radio wave skin depth) from natural ones is proposed. It is based on a new multipolarization parameter related to the ratio between the damping in the slick of specially normalized resonant and nonresonant signals calculated using the normalized radar cross-section model proposed by Kudryavtsev et al. (2003a). The technique is tested on RADARSAT-2 copolarization (VV/HH) synthetic aperture radar images of slicks of a priori known provenance (mineral oils, e.g., emulsion and crude oil, and plant oil served to model a natural slick) released during annual oil-on-water exercises in the North Sea in 2011 and 2012. It has been shown that the suggested multipolarization parameter gives new capabilities in interpreting slicks visible on synthetic aperture radar images while allowing discrimination between mineral oil and plant oil slicks.

  3. Research on using oil herding surfactants to thicken oil slicks in pack ice for in situ burning

    Energy Technology Data Exchange (ETDEWEB)

    Buist, I.; Morrison, J. [S.L. Ross Environmental Research Ltd., Ottawa, ON (Canada)

    2005-07-01

    The severe limitations of conventional containment and recovery systems for oil spills in pack ice have been demonstrated during skimmer tests conducted in the Alaskan Beaufort Sea. In-situ burning may be one of the few viable alternatives to quickly remove oil spilled in pack ice, but the slicks are often too thin, preventing effective ignition or burning. This study examined ways to thicken the slicks to the 2- to 5-mm range so that effective burns could be carried out. Specific chemical surface-active agents known as oil herders or oil collecting agents can be used to clear and contain oil slicks on water surfaces. Since these agents can spread quickly on water, only a small quantity is needed to clear thin films of oil from large areas of water. Applying a chemical herder around the periphery of spilled oil can contract the oil into a thicker slick. Two chemical products were developed and tested in the 1970s and 1980s: Shell Herder and Exxon OC-5 Oil Collector. However, they are no longer used because they were effective only in very calm conditions. Corexit EC9580 which exhibits similar slick herding abilities and which has a spreading pressure of 39.5 mN/m is still commercially available. This study tested formulations of herding agents for use in pack ice. Concerns regarding the potential toxicity risk of using these agents in pack ice were also addressed. The agents should not harm the environment because they have low toxicity and only very small quantities are used. Two series of tests conducted to assess the potential for herding agents to help ignite and effectively burn thin oil slicks in loose pack ice conditions. The agents proved to be effective on cold water and on thick slicks. The composition of the oil played an important role in determining potential efficiency. It was concluded that applying herders to thin oil slicks in pack ice shows considerable promise for thickening them for in-situ burning. 12 refs., 4 tabs., 17 figs.

  4. hsa-miR-125a-5p Enhances Invasion in Non-small Cell Lung Carcinoma Cell Lines by Upregulating Rock-1

    Directory of Open Access Journals (Sweden)

    Lili JIANG

    2009-10-01

    Full Text Available Background and objective MicroRNAs (miRNAs are endogenous, non-coding small RNA in eukaryotes. They recognize their target sites by incomplete base pairing and posttranscriptionally regulate gene expression, and function on a lot of complex vital processes of organisms. The objective of this work is to study how hsa-miR-125a-5p enhances the invasive ability of lung cancer cells. Methods The target gene and its target sites of hsa-miR-125a-5p were predicted by microRNA.org. We investigated Rock-1 mRNA and protein expressions by RT-PCR and Western blot according to the result of prediction further. The invasive ability of A549 cells, which were transfected with sense hsa-miR-125a-5p 2’-O-methyl oligonucleotide after being blocked by anti-Rock-1, was observed by Transwell. Results With RT-PCR and Western blot, Rock-1 mRNA and protein were both increased in A549 cells transfected with sense hsa-miR-125a-5p 2’-O-methyl oligonucleotide and were both decreased in the cells which transfected with antisense vs control groups. The invasive ability of A549 cells transfected with sense hsa-miR-125a-5p 2’-O-methyl oligonucleotide were weakened after being blocked by anti-Rock-1, vs non-blocking group by Transwell test. Conclusion hsa-miR-125a-5p could up-regulate Rock-1 and enhance invasion in lung cancer cells.

  5. The Effect of ROCK on TNF-α-Induced CXCL8 Secretion by Intestinal Epithelial Cell Lines is Mediated Through MKK4 and JNK Signaling

    Science.gov (United States)

    Perey, Aaron C.; Weishaar, Isabelle M.; McGee, Dennis W.

    2015-01-01

    Intestinal epithelial cells (IEC) play a role in mucosal inflammatory responses by producing important chemokines like CXCL8 when stimulated by TNF-α. Previously, we found that IEC cell lines required the Rho-associated kinase, ROCK, for CXCL8 responses after IL-1 stimulation. This study extends these findings by showing that inhibiting ROCK suppressed TNF-α-induced CXCL8 secretion by Caco-2 and DLD1 colonic epithelial cell lines and CXCL8 mRNA levels in Caco-2 cells. RNAi knockdown experiments indicated that the inhibitory effect was mediated by ROCK2, and not ROCK1. Inhibiting ROCK had no effect on TNF-stimulated IκBα phosphorylation and degradation or p38 MAPK phosphorylation indicating that ROCK plays no role in these signaling pathways. However, inhibiting ROCK suppressed TNF-induced phosphorylation of the p54 JNK isoform and phosphorylation of the upstream MKK4 kinase. These results suggest that ROCK is required for CXCL8 responses by TNF-stimulated IEC by affecting intracellular signaling through MKK4 and JNK. PMID:25577341

  6. Comparisons of Circular Transmit and Linear Receive Compact Polarimetric SAR Features for Oil Slicks Discrimination

    Directory of Open Access Journals (Sweden)

    Yu Li

    2015-01-01

    Full Text Available Compact polarimetric (CP synthetic aperture radar (SAR has proven its potential in distinguishing oil slicks and look-alikes. Polarimetric information can be retrieved directly from scattering vector or from reconstructed pseudo-Quad-Pol covariance matrix of CP SAR data. In this paper, we analysed features from Circular Transmit and Linear Receive (CTLR CP SAR data that are derived by taking both of these two methods. K-means clustering followed by accuracy assessment was also implemented for performance evaluation. Through experiments that were conducted based on L-band UAVSAR fully polarimetric data, it was found that optimum extraction methods varied for different features. The histogram analysis and segmentation results also demonstrated the comparable performance of CP SAR features in distinguishing different damping properties within oil slicks. This study proposed a framework of statistically analyzing polarimetric SAR (Pol-SAR features and provided guidelines for determining optimum feature extraction methods from CP SAR data and for marine oil-spills detection and classification.

  7. An oil slick spectral experiment of nearshore sea water in the East China Sea

    Institute of Scientific and Technical Information of China (English)

    WANG Difeng; PAN Delu; GONG Fang; WANG Tianyu; ZHAN Yuanzeng

    2013-01-01

    Along with the rapid advance in global industrialization, oil spill events caused by offshore operations, trans-portation and accidents are increasing. Compared with ship surveys, monitoring oil spills through remote sensing has real-time, comprehensive, low-cost advantages, which can effectively guide cleaning and evalu-ation, and reduce the marine ecological destruction resulting from oil spills. Therefore, studying the remote sensing mechanism used to monitor marine oil spills is of great significance for ecological environmen-tal protection. This paper describes an experiment and corresponding analysis based on the above-water method, using the East China Sea coastal turbid water. The analysis shows that“upward short-wave”in ultraviolet and blue-purple bands and its displacement, along with the changing thickness, are important characteristics for distinguishing between the oil slick and the sea water, and also to differentiate oil slicks of different thicknesses. From blue to near-infrared bands, the spectrum of lube oil is flatter than that of diesel, and the diesel spectrum rises faster than the lube spectrum on the right side of the trough at 400 nm. These two features form an important basis for differentiating diesel from lube oil. These analyses will further the development of oil spill remote sensing in the East China Sea.

  8. Prediction model of oil slick movement in the Nemunas river (Lithuania)

    International Nuclear Information System (INIS)

    Full text : Oil products (petroleum products) were used to fuel airplanes, cars and trucks, to heat the houses, and to make products like medicines and plastics. Even petroleum products make life easier, but extraction, production, movement, and use of them cause environment pollution in air, soil and water. There are several sources of water pollution, like ship traffic, oil refineries and other industry, which together deteriorate the river water quality and disturb the life within rivers and lakes. Rain as it falls through the air, or drains from urban areas and farmland, absorbs contaminants. The model has been developed based on the solution of the governing partial differential equations of flow and oil products for predicting the oil slick transformation in the rivers. In the present model, the processes included are advection, diffusion, evaporation and dissolution. The model can take into account all losses of oil products during the movement of oil slick. It can be used either as a real time basis to predict the movement of oil spill or as a scenario model to analyse to possible impact of accidental oil spill in to the rivers

  9. The ROCK inhibitor Y-27632 improves recovery of human embryonic stem cells after fluorescence-activated cell sorting with multiple cell surface markers.

    Directory of Open Access Journals (Sweden)

    Nil Emre

    Full Text Available BACKGROUND: Due to the inherent sensitivity of human embryonic stem cells (hESCs to manipulations, the recovery and survival of hESCs after fluorescence-activated cell sorting (FACS can be low. Additionally, a well characterized and robust methodology for performing FACS on hESCs using multiple-cell surface markers has not been described. The p160-Rho-associated coiled kinase (ROCK inhibitor, Y-27632, previously has been identified as enhancing survival of hESCs upon single-cell dissociation, as well as enhancing recovery from cryopreservation. Here we examined the application of Y-27632 to hESCs after FACS to improve survival in both feeder-dependent and feeder-independent growth conditions. METHODOLOGY/PRINCIPAL FINDINGS: HESCs were sorted using markers for SSEA-3, TRA-1-81, and SSEA-1. Cells were plated after sorting for 24 hours in either the presence or the absence of Y-27632. In both feeder-dependent and feeder-independent conditions, cell survival was greater when Y-27632 was applied to the hESCs after sort. Specifically, treatment of cells with Y-27632 improved post-sort recovery up to four fold. To determine the long-term effects of sorting with and without the application of Y-27632, hESCs were further analyzed. Specifically, hESCs sorted with and without the addition of Y-27632 retained normal morphology, expressed hESC-specific markers as measured by immunocytochemistry and flow cytometry, and maintained a stable karyotype. In addition, the hESCs could differentiate into three germ layers in vitro and in vivo in both feeder-dependent and feeder-independent growth conditions. CONCLUSIONS/SIGNIFICANCE: The application of Y-27632 to hESCs after cell sorting improves cell recovery with no observed effect on pluripotency, and enables the consistent recovery of hESCs by FACS using multiple surface markers. This improved methodology for cell sorting of hESCs will aid many applications such as removal of hESCs from secondary cell types

  10. Rho-ROCK and Rac-PAK signaling pathways have opposing effects on the cell-to-cell spread of Marek's Disease Virus.

    Directory of Open Access Journals (Sweden)

    Nicolas Richerioux

    Full Text Available Marek's Disease Virus (MDV is an avian alpha-herpesvirus that only spreads from cell-to-cell in cell culture. While its cell-to-cell spread has been shown to be dependent on actin filament dynamics, the mechanisms regulating this spread remain largely unknown. Using a recombinant BAC20 virus expressing an EGFPVP22 tegument protein, we found that the actin cytoskeleton arrangements and cell-cell contacts differ in the center and periphery of MDV infection plaques, with cells in the latter areas showing stress fibers and rare cellular projections. Using specific inhibitors and activators, we determined that Rho-ROCK pathway, known to regulate stress fiber formation, and Rac-PAK, known to promote lamellipodia formation and destabilize stress fibers, had strong contrasting effects on MDV cell-to-cell spread in primary chicken embryo skin cells (CESCs. Inhibition of Rho and its ROCKs effectors led to reduced plaque sizes whereas inhibition of Rac or its group I-PAKs effectors had the adverse effect. Importantly, we observed that the shape of MDV plaques is related to the semi-ordered arrangement of the elongated cells, at the monolayer level in the vicinity of the plaques. Inhibition of Rho-ROCK signaling also resulted in a perturbation of the cell arrangement and a rounding of plaques. These opposing effects of Rho and Rac pathways in MDV cell-to-cell spread were validated for two parental MDV recombinant viruses with different ex vivo spread efficiencies. Finally, we demonstrated that Rho/Rac pathways have opposing effects on the accumulation of N-cadherin at cell-cell contact regions between CESCs, and defined these contacts as adherens junctions. Considering the importance of adherens junctions in HSV-1 cell-to-cell spread in some cell types, this result makes of adherens junctions maintenance one potential and attractive hypothesis to explain the Rho/Rac effects on MDV cell-to-cell spread. Our study provides the first evidence that MDV cell-to-cell

  11. RhoA/ROCK pathway regulates hypoxia-induced myocardial cell apoptosis

    Institute of Scientific and Technical Information of China (English)

    Yi Huang; Jiang-bin Chen; Bo Yang; Hui Shen; Jin-Jun Liang; Qiong Luo

    2014-01-01

    Objective:To observe the regulatory effects of RhoA/ROCK pathway on the apoptosis of cardiac myocyte induced by anoxia and its mechanism. Methods:The model of cardiac myocyte anoxia was established. The beat pulsations and apoptosis rates after 1 h, 3 h, 6 h, 9 h and 12 h of anoxia were recorded and the expressions of RhoA, ROCK1/2, p-PI3K, p-AKT and caspae-3 were detected, too. The apoptosis and the expressions of related proteins were detected after RNAi of RhoA and the inhibition of ROCK by Y-27632. Results:The beat pulsations after 1 h, 3 h, 6 h, 9 h and 12 h decreased gradually but the apoptosis rates increased gradually, and the expressions of RhoA, ROCK1/2, p-PI3K, p-AKT and caspase-3 were increasing along with the increasing duration of anoxia. The apoptotic rates after 1 h, 3 h, 6 h, 9 h and 12 h of anoxia were (4.36±0.98)%, (8.36±2.12)%, (15.32±3.62)%, (18.68±4.83)%and (24.56±6.22)%, respectively and decreased more significantly than control group in different time points of anoxia (P<0.05), and the expressions of RhoA, ROCK1/2, p-PI3K, p-AKT and caspase-3 decreased significantly (P<0.05). The apoptosis rate and the expressions of RhoA, ROCK1/2, p-PI3K, p-AKT and caspase-3 decreased significantly (P<0.05) after the inhibition of ROCK by Y-27632 (P<0.05). Conclusions:RhoA/ROCK pathway plays a critical role in the regulation of the apoptosis of cardiac myocyte induced by anoxia, which may be accompanied by regulating the activity of PI3K/AKT/Caspase-3 pathway.

  12. Rock stresses (Grimsel rock laboratory)

    International Nuclear Information System (INIS)

    On the research and development project 'Rock Stress Measurements' the BGR has developed and tested several test devices and methods at GTS for use in boreholes at a depth of 200 m and has carried out rock mechanical and engineering geological investigations for the evaluation and interpretation of the stress measurements. The first time a computer for data processing was installed in the borehole together with the BGR-probe. Laboratory tests on hollow cylinders were made to study the stress-deformation behavior. To validate and to interprete the measurement results some test methods were modelled using the finite-element method. The dilatometer-tests yielded high values of Young's modulus, whereas laboratory tests showed lower values with a distinct deformation anisotropy. Stress measurements with the BGR-probe yielded horizontal stresses being higher than the theoretical overburden pressure and vertical stresses which agree well with the theoretical overburden pressure. These results are comparable to the results of the hydraulic fracturing tests, whereas stresses obtained with CSIR-triaxial cells are generally lower. The detailed geological mapping of the borehole indicated relationships between stress and geology. With regard to borehole depth different zones of rock structure joint frequency, joint orientation, and orientation of microfissures as well as stress magnitude, stress direction, and degree of deformation anisotropy could be distinguished. (orig./HP)

  13. Induction of Apoptosis by L-NMMA, via FKHRL1/ROCK Pathway in Human Gastric Cancer Cells

    Institute of Scientific and Technical Information of China (English)

    YONG-ZHONG WANG; ZHEN-QING FENG

    2006-01-01

    To investigate the apoptosis-inducing effect of endogenous nitric oxide (NO) suppression in gastric cancer cells and its mechanisms. Methods Apoptosis of gastric cancer cells was detected by flow cytometry. Expression of phosphorylated FKHRL1 (thr-32, ser-253) and FKHRL1 in gastric cancer cells was analyzed using Western blotting.Immunofluorescence assay was performed to localize the intracellular phosphorylated FKHRL1 (thr-32, ser-253) and FKHRL1.Transfection of FKHRL1-HA wild type and mutant FKHRL1-HA T32A constructs was performed by lipofectamine plus reagent. NO generation was determined by Griess reaction. Results Gastric cancer cells were significantly apoptotic after treatment with NG-monomethyl-L-arginine (L-NMMA, a nitric oxide synthase inhibitor), compared with the control (P<0.01).The apoptosis of gastric cancer cells induced by L-NMMA was dose-dependent and time-independent. However, the Z-DEVD-fmk, a caspase-3, 6, 7, 8, 10 inhibitor, did not prevent the apoptosis. The immunofluorescence assays showed that FKHRL1 protein was strongly expressed in the nucleu and p-FKHRL1 thr-32 protein was strongly expressed in the cytoplasm of SGC-7901 cells when endogenous nitric oxide generation was blocked by L-NMMA, but no change in FKHRL1 ser-253phosphorylation. Nevertheless, ROCK protein was strongly expressed in p-FKHRL1 thr-32-positive SGC-7901 cells. The wortmannin, an inhibitor of phosphoinositol-3-OH kinase (PI3K), did not block the phosphorylated FKHRL1 thr-32 protein induced by L-NMMA. However, Y-27632, a specific inhibitor of the protein kinase ROCK, significantly blocked apoptosis induced by phosphorylated FKHRL1 thr-32 (P<0.01), which was mediated by L-NMMA. A significant decrease in NO generation (P<0.01) and a significant increase in apoptosis (P<0.01) were observed when FKHRL1-HA wild-type cells were transfected, which caused increased FKHRL1 thr-32 phosphorylation. Conclusions L-NMMA triggers gastric carcinoma cell apoptosis, possibly by

  14. Slick Prospects

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    As a pillar of the country’s financial system, Chinese banks are playing a bigger role in economic revitalization and rebalancing. But challenges still lie ahead on their path of financial reform and global expansion. Bankers from home and abroad discussed these issues at the Institute of International Finance (IIF) Spring Membership Meeting held on June 10-12 in Beijing. The IIF is a leading global association of financial service firms with more than 360 members across the world. Edited excerpts of the bankers’ comments follow.

  15. ROCK2 signaling is required to induce a subset of T follicular helper cells through opposing effects on STATs in autoimmune settings.

    Science.gov (United States)

    Weiss, Jonathan M; Chen, Wei; Nyuydzefe, Melanie S; Trzeciak, Alissa; Flynn, Ryan; Tonra, James R; Marusic, Suzana; Blazar, Bruce R; Waksal, Samuel D; Zanin-Zhorov, Alexandra

    2016-01-01

    Rho-associated kinase 2 (ROCK2) determines the balance between human T helper 17 (TH17) cells and regulatory T (Treg) cells. We investigated its role in the generation of T follicular helper (TFH) cells, which help to generate antibody-producing B cells under normal and autoimmune conditions. Inhibiting ROCK2 in normal human T cells or peripheral blood mononuclear cells from patients with active systemic lupus erythematosus (SLE) decreased the number and function of TFH cells induced by activation ex vivo. Moreover, inhibition of ROCK2 activity decreased the abundance of the transcriptional regulator Bcl6 (B cell lymphoma 6) and increased that of Blimp1 by reducing the binding of signal transducer and activator of transcription 3 (STAT3) and increasing that of STAT5 to the promoters of the genes Bcl6 and PRDM1, respectively. In the MRL/lpr murine model of SLE, oral administration of the selective ROCK2 inhibitor KD025 resulted in a twofold reduction in the numbers of TFH cells and antibody-producing plasma cells in the spleen, as well as a decrease in the size of splenic germinal centers, which are the sites of interaction between TFH cells and B cells. KD025-treated mice showed a substantial improvement in both histological and clinical scores compared to those of untreated mice and had reduced amounts of Bcl6 and phosphorylated STAT3, as well as increased STAT5 phosphorylation. Together, these data suggest that ROCK2 signaling plays a critical role in controlling the development of TFH cells induced by autoimmune conditions through reciprocal regulation of STAT3 and STAT5 activation. PMID:27436361

  16. Uranium Mill Tailings Remedial Action Project (UMTRAP), Slick Rock, Colorado, Revision 1. Volume 2, Calculations, Final design for construction

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-09-01

    Volume two contains calculations for: embankment design--slope stability analysis; embankment design--excavation stability; embankment design--settlement and cover cracking analysis; radon barrier design--statistical analysis of ra-226 concentrations for North Continent and Union Carbide sites; radon barrier design--RAECOM input data; radon barrier design--design thickness; and cover design--frost penetration depth.

  17. Uranium Mill Tailings Remedial Action Project (UMTRAP), Slick Rock, Colorado, Revision 1. Bid schedule, special conditions, specifications, and subcontract drawings

    International Nuclear Information System (INIS)

    This volume contains: bidding requirements; terms and conditions; specifications for Division 1 -- general requirements; specifications for Division 2 -- sitework; specifications for Divisions 5 -- metals; subcontract drawings, (general, Union Carbide processing site, North Continent processing site, and Burro Canyon disposal site)

  18. Uranium Mill Tailings Remedial Action Project (UMTRAP), Slick Rock, Colorado, Revision 1. Bid schedule, special conditions, specifications, and subcontract drawings

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-10-01

    This volume contains: bidding requirements; terms and conditions; specifications for Division 1 -- general requirements; specifications for Division 2 -- sitework; specifications for Divisions 5 -- metals; subcontract drawings, (general, Union Carbide processing site, North Continent processing site, and Burro Canyon disposal site).

  19. Uranium Mill Tailings Remedial Action Project (UMTRAP), Slick Rock, Colorado, Revision 1. Volume 1, Calculations, Final design for construction

    International Nuclear Information System (INIS)

    Volume one contains calculations for: embankment design--embankment material properties; Union Carbide site--bedrock contours; vicinity properties--origin of contamination; North Continent and Union Carbide sites contaminated materials--excavation quantities; and demolition debris--quantity estimate

  20. KREEP Rocks

    Institute of Scientific and Technical Information of China (English)

    邹永廖; 徐琳; 欧阳自远

    2004-01-01

    KREEP rocks with high contents of K, REE and P were first recognized in Apollo-12 samples, and it was confirmed later that there were KREEP rock fragments in all of the Apollo samples, particularly in Apollo-12 and-14 samples. The KREEP rocks distributed on the lunar surface are the very important objects of study on the evolution of the moon, as well as to evaluate the utilization prospect of REE in KREEP rocks. Based on previous studies and lunar exploration data, the authors analyzed the chemical and mineral characteristics of KREEP rocks, the abundance of Th on the lunar surface materials, the correlation between Th and REE of KREEP rocks in abundance, studied the distribution regions of KREEP rocks on the lunar surface, and further evaluated the utilization prospect of REE in KREEP rocks.

  1. Rock Stars

    Institute of Scientific and Technical Information of China (English)

    张国平

    2000-01-01

    Around the world young people are spending unbelievable sums of money to listen to rock music. Forbes Magazine reports that at least fifty rock stars have incomes between two million and six million dollars per year.

  2. Rock Finding

    Science.gov (United States)

    Rommel-Esham, Katie; Constable, Susan D.

    2006-01-01

    In this article, the authors discuss a literature-based activity that helps students discover the importance of making detailed observations. In an inspiring children's classic book, "Everybody Needs a Rock" by Byrd Baylor (1974), the author invites readers to go "rock finding," laying out 10 rules for finding a "perfect" rock. In this way, the…

  3. A robust active contour edge detection algorithm based on local Gaussian statistical model for oil slick remote sensing image

    Science.gov (United States)

    Jing, Yu; Wang, Yaxuan; Liu, Jianxin; Liu, Zhaoxia

    2015-08-01

    Edge detection is a crucial method for the location and quantity estimation of oil slick when oil spills on the sea. In this paper, we present a robust active contour edge detection algorithm for oil spill remote sensing images. In the proposed algorithm, we define a local Gaussian data fitting energy term with spatially varying means and variances, and this data fitting energy term is introduced into a global minimization active contour (GMAC) framework. The energy function minimization is achieved fast by a dual formulation of the weighted total variation norm. The proposed algorithm avoids the existence of local minima, does not require the definition of initial contour, and is robust to weak boundaries, high noise and severe intensity inhomogeneity exiting in oil slick remote sensing images. Furthermore, the edge detection of oil slick and the correction of intensity inhomogeneity are simultaneously achieved via the proposed algorithm. The experiment results have shown that a superior performance of proposed algorithm over state-of-the-art edge detection algorithms. In addition, the proposed algorithm can also deal with the special images with the object and background of the same intensity means but different variances.

  4. Quantitative determination of oil films/slicks from water surfaces using a modified solid-phase extraction (SPE) sampling method

    International Nuclear Information System (INIS)

    A method to quantify oil films and slicks floating on water surfaces has been developed using a modified solid-phase extraction (SPE) procedure using C-18 disks. SPE is a commonly used method for isolating hydrophobic organic compounds from aqueous solutions in preparation for analysis. The objective of the study was to determine if surface sampling of oil slicks using this procedure is linear, precise and consistently yields quantitative recoveries of oil per unit area. The effectiveness of oil removal from a sandy beach in meso-scale wave tanks using different shoreline cleaner products was also assessed. Nine oil loadings were sampled with C18-SPE disks in replicates from the surface of 1 litre beakers. The results of these controlled laboratory experiments indicated that the sampling efficiency was strongly linear over the whole range tested, the variability was below 10 per cent and the oil was collected by the SPE disks in a 1:1 ratio relative to the water surface loadings. It was concluded that this method is a promising means by which to quantify and identifying oils present in meso-scale to large-scale slick in both experimental and natural settings. 17 refs., 1 tab., 3 figs

  5. The hippocampus of the eastern rock sengi: cytoarchitecture, markers of neuronal function, principal cell numbers, and adult neurogenesis.

    Science.gov (United States)

    Slomianka, Lutz; Drenth, Tanja; Cavegn, Nicole; Menges, Dominik; Lazic, Stanley E; Phalanndwa, Mashudu; Chimimba, Christian T; Amrein, Irmgard

    2013-01-01

    The brains of sengis (elephant shrews, order Macroscelidae) have long been known to contain a hippocampus that in terms of allometric progression indices is larger than that of most primates and equal in size to that of humans. In this report, we provide descriptions of hippocampal cytoarchitecture in the eastern rock sengi (Elephantulus myurus), of the distributions of hippocampal calretinin, calbindin, parvalbumin, and somatostatin, of principal neuron numbers, and of cell numbers related to proliferation and neuronal differentiation in adult hippocampal neurogenesis. Sengi hippocampal cytoarchitecture is an amalgamation of characters that are found in CA1 of, e.g., guinea pig and rabbits and in CA3 and dentate gyrus of primates. Correspondence analysis of total cell numbers and quantitative relations between principal cell populations relate this sengi to macaque monkeys and domestic pigs, and distinguish the sengi from distinct patterns of relations found in humans, dogs, and murine rodents. Calretinin and calbindin are present in some cell populations that also express these proteins in other species, e.g., interneurons at the stratum oriens/alveus border or temporal hilar mossy cells, but neurons expressing these markers are often scarce or absent in other layers. The distributions of parvalbumin and somatostatin resemble those in other species. Normalized numbers of PCNA+ proliferating cells and doublecortin-positive (DCX+) differentiating cells of neuronal lineage fall within the overall ranges of murid rodents, but differed from three murid species captured in the same habitat in that fewer DCX+ cells relative to PCNA+ were observed. The large and well-differentiated sengi hippocampus is not accompanied by correspondingly sized cortical and subcortical limbic areas that are the main hippocampal sources of afferents and targets of efferents. This points to intrinsic hippocampal information processing as the selective advantage of the large sengi hippocampus

  6. The hippocampus of the eastern rock sengi: cytoarchitecture, markers of neuronal function, principal cell numbers and adult neurogenesis

    Directory of Open Access Journals (Sweden)

    Lutz eSlomianka

    2013-10-01

    Full Text Available The brains of sengis (elephant shrews, order Macroscelidae have long been known to contain a hippocampus that in terms of allometric progression indices is larger than that of most primates and equal in size to that of humans. In this report, we provide descriptions of hippocampal cytoarchitecture in the eastern rock sengi (Elephantulus myurus, of the distributions of hippocampal calretinin, calbindin, parvalbumin and somatostatin, of principal neuron numbers and of cell numbers related to proliferation and neuronal differentiation in adult hippocampal neurogenesis. Sengi hippocampal cytoarchitecture is an amalgamation of characters that are found in CA1 of, e.g., guinea pig and rabbits and in CA3 and dentate gyrus of primates. Correspondence analysis of total cell numbers and quantitative relations between principal cell populations relate this sengi to macaque monkeys and domestic pigs, and distinguish the sengi from distinct patterns of relations found in humans, dogs and murine rodents. Calretinin and calbindin are present in some cell populations that also express these proteins in other species, e.g., interneurons at the stratum oriens/alveus border or temporal hilar mossy cells, but neurons expressing these markers are often scarce or absent in other layers. The distributions of parvalbumin and somatostatin resemble those in other species. Normalized numbers of PCNA+ proliferating cells and doublecortin+ differentiating cells of neuronal lineage fall within the overall ranges of murid rodents, but differed from three murid species captured in the same habitat in that fewer doublecortin+ cells relative to PCNA+ were observed . The large and well-differentiated sengi hippocampus is not accompanied by correspondingly sized cortical and subcortical limbic areas that are the main hippocampal sources of afferents and targets of efferents. This points to intrinsic hippocampal information processing as the selective advantage of the large sengi

  7. HIV-1 Tat Regulates Occludin and Aβ Transfer Receptor Expression in Brain Endothelial Cells via Rho/ROCK Signaling Pathway

    Science.gov (United States)

    Chen, Yanlan; Jiang, Wenlin; Wu, Xianghong; Ye, Biao; Zhou, Xiaoting

    2016-01-01

    HIV-1 transactivator protein (Tat) has been shown to play an important role in HIV-associated neurocognitive disorders. The aim of the present study was to evaluate the relationship between occludin and amyloid-beta (Aβ) transfer receptors in human cerebral microvascular endothelial cells (hCMEC/D3) in the context of HIV-1-related pathology. The protein expressions of occludin, receptor for advanced glycation end products (RAGE), and low-density lipoprotein receptor-related protein 1 (LRP1) in hCMEC/D3 cells were examined using western blotting and immunofluorescent staining. The mRNA levels of occludin, RAGE, and LRP1 were measured using quantitative real-time polymerase chain reaction. HIV-1 Tat at 1 µg/mL and the Rho inhibitor hydroxyfasudil (HF) at 30 µmol/L, with 24 h exposure, had no significant effect on hCMEC/D3 cell viability. Treatment with HIV-1 Tat protein decreased mRNA and protein levels of occludin and LRP1 and upregulated the expression of RAGE; however, these effects were attenuated by HF. These data suggest that the Rho/ROCK signaling pathway is involved in HIV-1 Tat-mediated changes in occludin, RAGE, and LRP1 in hCMEC/D3 cells. HF may have a beneficial influence by protecting the integrity of the blood-brain barrier and the expression of Aβ transfer receptors.

  8. {delta}-ALAD activity variations in red blood cells in response to lead accumulation in rock doves (Columba livia)

    Energy Technology Data Exchange (ETDEWEB)

    Gonzalez, M.; Tejedor, M.C. [Universidad de Alcala de Henares (Spain)

    1992-10-01

    The enzyme {delta}-aminolevulinic acid dehydratase ({delta}-ALAD, E.C. 4.2.1.24), catalyses the second step of the haeme biosynthetic pathway and is required to maintain the haemoglobin and cytochrome content in red cells. {delta}-ALAD is not only found in bone marrow cells, the major site of haeme synthesis, but also in circulating erythrocytes and other tissues. An inverse correlation was found between {delta}-ALAD activity in red blood cells and lead concentration in the blood. The degree of {delta}-ALAD inhibition in erythrocytes has been widely accepted as a standard bioassay to detect acute and chronic lead exposure in humans and in avians. The value of this parameter as an indicator for environmental lead has been often reported in doves and Scanlon. In lead-treated rats, an increase in {delta}-ALAD activity in bone marrow cells and in blood samples was shown by radioimmunoassay at 5 and 9 days after the treatment. Similarly, the amount of {delta}-ALAD seems to be more sensitive to lead in avian species than in mammals, the usefulness of blood {delta}-ALAD activity as an index of lead exposure has already been questioned by Hutton in the pigeon and by Jaffe et al. in humans. The present investigation studied the toxic effects of lead on rock dove red blood cell {delta}-ALAD activity in two situations: in doves treated with lead acetate in the laboratory and in doves exposed to the environment of Alcala de Henares. The final lead blood concentrations were lower in the environmental than in the laboratory doves. {delta}-ALAD activity in bone marrow cells and the relationships between lead accumulation and enzyme activity in red cells, are examined. 20 refs., 5 figs., 1 tab.

  9. ROCK inhibitor Y-27632 inhibits the growth, migration, and invasion of Tca8113 and CAL-27 cells in tongue squamous cell carcinoma.

    Science.gov (United States)

    Wang, Zhi-Ming; Yang, Dong-Sheng; Liu, Jie; Liu, Hong-Bo; Ye, Ming; Zhang, Yu-Fei

    2016-03-01

    The objective of this study is to determine the effects of Rho-associated coiled-coil containing protein kinase (ROCK) inhibitor Y-27632 on the growth, invasion, and migration of Tca8113 and CAL-27 cells in tongue squamous cell carcinoma (TSCC). The methods of the study are as follows: After being routinely cultured for 24 h, Tca8113 and CAL-27 cells were treated with Y-27632 solution. The morphological change of Y-27632-treated cells was observed under an optical microscope and an inverted microscope; MTT assay was performed to measure the optical density (OD) of cells and calculate cell growth inhibition rate; the change of apoptosis was detected by AnnexinV-FITC/PI assay; cell invasion and migration were measured by Transwell assay. The results were as follows: (1) With increasing concentration of Y-27632, cell morphology changed and cell apoptosis appeared; (2) MTT assay showed that inhibition effect of Y-27632 on Tca8113 and CAL-27 cells was enhanced with increasing concentrations and time (all P Y-27632; (4) Transwell assay showed, after a treatment with Y-27632, the number of migrated and invaded Tca8113 and CAL-27 cells in each group was statistically different (all P Y-27632 was decreased and less Tca8113 and CAL-27 cells in experimental groups passed through polycarbonate membrane (all P Y-27632 can inhibit the growth, invasion, and migration of Tca8113 and CAL-27 cells, suggesting that Y-27632 may be therapeutically useful in TSCC.

  10. Effects of sediment amended with Deepwater Horizon incident slick oil on the infaunal amphipod Leptocheirus plumulosus.

    Science.gov (United States)

    Lotufo, Guilherme R; Farrar, J Daniel; Biedenbach, James M; Laird, Jennifer G; Krasnec, Michelle O; Lay, Claire; Morris, Jeffrey M; Gielazyn, Michel L

    2016-08-15

    Crude oil released from the Deepwater Horizon disaster into the Gulf of Mexico posed potential impacts to infaunal invertebrates inhabiting near shore habitats. The effects of sediment-associated weathered slick oil on the amphipod Leptocheirus plumulosus was assessed using 28-d exposures to total PAH sediment concentrations ranging from 0.3 to 24mg/kg (sum of 50 PAHs or tPAH50). Survival and growth rate were significantly decreased in the 2.6, 11.4 and 24.2mg/kg treatments, but only growth in 5.5mg/kg. Offspring production was dramatically decreased but was variable and significantly different only for 24.2mg/kg. The concentrations associated with 20% decreases relative to reference were 1.05 (95% CI=0-2.89) mg/kg tPAH50 for growth rate and 0.632 (95% CI=0.11-2.15) mg/kg tPAH50 for offspring production. The concentrations of PAHs affecting amphipods are within the range of concentrations measured in marsh areas reportedly impacted by DWH oil after its release. PMID:27267114

  11. Lung epithelial cell-derived extracellular vesicles activate macrophage-mediated inflammatory responses via ROCK1 pathway.

    Science.gov (United States)

    Moon, H-G; Cao, Y; Yang, J; Lee, J H; Choi, H S; Jin, Y

    2015-01-01

    Despite decades of research, the pathogenesis of acute respiratory distress syndrome (ARDS) remains poorly understood, thus impeding the development of effective treatment. Diffuse alveolar damage (DAD) and lung epithelial cell death are prominent features of ARDS. Lung epithelial cells are the first line of defense after inhaled stimuli, such as in the case of hyperoxia. We hypothesized that lung epithelial cells release 'messenger' or signaling molecules to adjacent or distant macrophages, thereby initiating or propagating inflammatory responses after noxious insult. We found that, after hyperoxia, a large amount of extracellular vesicles (EVs) were generated and released into bronchoalveolar lavage fluid (BALF). These hyperoxia-induced EVs were mainly derived from live lung epithelial cells as the result of hyperoxia-associated endoplasmic reticulum (ER) stress. These EVs were remarkably different from epithelial 'apoptotic bodies', as reflected by the significantly smaller size and differentially expressed protein markers. These EVs fall mainly in the size range of the exosomes and smaller microvesicles (MVs) (50-120 nm). The commonly featured protein markers of apoptotic bodies were not found in these EVs. Treating alveolar macrophages with hyperoxia-induced, epithelial cell-derived EVs led to an increased secretion of pro-inflammatory cytokines and macrophage inflammatory protein 2 (MIP-2). Robustly increased macrophage and neutrophil influx was found in the lung tissue of the mice intranasally treated with hyperoxia-induced EVs. It was determined that EV-encapsulated caspase-3 was largely responsible for the alveolar macrophage activation via the ROCK1 pathway. Caspase-3-deficient EVs induced less cytokine/MIP-2 release, reduced cell counts in BALF, less neutrophil infiltration and less inflammation in lung parenchyma, both in vitro and in vivo. Furthermore, the serum circulating EVs were increased and mainly derived from lung epithelial cells after

  12. Diavik Waste Rock Project: Evolution of Mineral Weathering, Element Release, and Acid Generation and Neutralization during a Five-Year Humidity Cell Experiment

    OpenAIRE

    Jeff B. Langman; Mandy L. Moore; Carol J. Ptacek; Leslie Smith; David Sego; David W. Blowes

    2014-01-01

    A five-year, humidity-cell experiment was used to study the weathering evolution of a low-sulfide, granitic waste rock at 5 and 22 °C. Only the rock with the highest sulfide content (0.16 wt %) released sufficient acid to overcome a limited carbonate acid-neutralization capacity and produce a substantial decline in pH. Leached SO4 and Ca quickly increased then decreased during the first two years of weathering. Sulfide oxidation continued to release acid and SO4 after carbonate depletion, res...

  13. Space-based laser-powered orbital transfer vehicle (Project SLICK)

    Science.gov (United States)

    1988-01-01

    A conceptual design study of a laser-powered orbital transfer vehicle (LOTV) is presented. The LOTV, nicknamed SLICK (Space Laser Interorbital Cargo Kite), will be utilized for the transfer of 16000 kg of cargo between Low Earth Orbit (LEO) and either Geosynchronous Earth Orbit (GEO) or Low Lunar Orbit (LLO). This design concentrates primarily on the LEO/GEO scenario, which will have typical LEO-to-GEO trip time of 6 days and two return versions. One version uses an all propulsive return while the other utilizes a ballute aerobrake for the return trip. Furthermore, three return cargo options of 16000 kg, 5000 kg (standard option), and 1600 kg are considered for this scenario. The LEO/LLO scenario uses only a standard, aerobraked version. The basic concept behind the LOTV is that the power for the propulsion system is supplied by a source separate from the LOTV itself. For the LEO/GEO scenario the LOTV utilizes a direct solar-pumped iodide laser and possibly two relay stations, all orbiting at an altitude of one Earth radius and zero inclination. An additional nuclear-powered laser is placed on the Moon for the LEO/LLO scenario. The propulsion system of the LOTV consists of a single engine fueled with liquid hydrogen. The laser beam is captured and directed by a four mirror optical system through a window in the thrust chamber of the engine. There, seven plasmas are created to convert the laser beam energy into thermal energy at an efficiency of at least 50 percent. For the LEO/LLO scenario the laser propulsion is supplemented by LH2/LOX chemical thrusters.

  14. Automatic Calculation of Oil Slick Area from Multiple SAR Acquisitions for Deepwater Horizon Oil Spill

    Science.gov (United States)

    Osmanoğlu, B.; Özkan, C.; Sunar, F.; Staples, G.

    2012-07-01

    The Deepwater Horizon oil spill occurred in the Gulf of Mexico in April 2010 and became the largest accidental marine oil spill in history. Oil leaked continuously between April 20th and July 15th of 2010, releasing about 780, 000m3 of crude oil into the Gulf of Mexico. The oil spill caused extensive economical and ecological damage to the areas it reached, affecting the marine and wildlife habitats along with fishing and tourism industries. For oil spill mitigation efforts, it is important to determine the areal extent, and most recent position of the contaminated area. Satellitebased oil pollution monitoring systems are being used for monitoring and in hazard response efforts. Due to their high accuracy, frequent acquisitions, large area coverage and day-and-night operation Synthetic Aperture Radar (SAR) satellites are a major contributer of monitoring marine environments for oil spill detection. We developed a new algorithm for determining the extent of the oil spill from multiple SAR images, that are acquired with short temporal intervals using different sensors. Combining the multi-polarization data from Radarsat-2 (C-band), Envisat ASAR (C-band) and Alos-PALSAR (L-band) sensors, we calculate the extent of the oil spill with higher accuracy than what is possible from only one image. Short temporal interval between acquisitions (hours to days) allow us to eliminate artifacts and increase accuracy. Our algorithm works automatically without any human intervention to deliver products in a timely manner in time critical operations. Acquisitions using different SAR sensors are radiometrically calibrated and processed individually to obtain oil spill area extent. Furthermore the algorithm provides probability maps of the areas that are classified as oil slick. This probability information is then combined with other acquisitions to estimate the combined probability map for the spill.

  15. A collapsin response mediator protein 2 isoform controls myosin II-mediated cell migration and matrix assembly by trapping ROCK II

    DEFF Research Database (Denmark)

    Yoneda, Atsuko; Morgan-Fisher, Marie; Wait, Robin;

    2012-01-01

    Collapsin response mediator protein 2 (CRMP-2) is known as a regulator of neuronal polarity and differentiation through microtubule assembly and trafficking. Here, we show that CRMP-2 is ubiquitously expressed and a splice variant (CRMP-2L), which is expressed mainly in epithelial cells among...... binding domains but also trapped and inhibited the kinase. CRMP-2L protein levels profoundly affected haptotactic migration and the actin-myosin cytoskeleton of carcinoma cells as well as nontransformed epithelial cell migration in a ROCK activity-dependent manner. Moreover, the ectopic expression of CRMP...

  16. Protective effect of Ac-SDKP on alveolar epithelial cells through inhibition of EMT via TGF-β1/ROCK1 pathway in silicosis in rat.

    Science.gov (United States)

    Deng, Haijing; Xu, Hong; Zhang, Xianghong; Sun, Yue; Wang, Ruimin; Brann, Darrell; Yang, Fang

    2016-03-01

    The epithelial-mesenchymal transition (EMT) is a critical stage during the development of silicosis fibrosis. In the current study, we hypothesized that the anti-fibrotic tetrapeptide, N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP) may exert its anti-fibrotic effects via activation of the TGF-β1/ROCK1 pathway, leading to inhibition of EMT. To address this hypothesis, we first examined the effect of Ac-SDKP upon EMT using an in vivo rat silicosis model, as well as in an in vitro model of TGF-β1-induced EMT. Confocal laser scanning microscopy was used to examine colocalization of surfactant protein A (SP-A), fibroblast specific protein-1 (FSP-1) and α-smooth muscle actin (α-SMA) in vivo. Western blot analysis was used to examine for changes in the protein levels of E-cadherin (E-cad) and SP-A (epithelial cell markers), vimentin (mesenchymal cell marker), α-SMA (active myofibroblast marker), and collagen I and III in both in vivo and in vitro experiments. Secondly, we utilized Western blot analysis and confocal laser scanning microscopy to examine the protein expression of TGF-β1 and ROCK1 in in vivo and in vitro studies. The results revealed that Ac-SDKP treatment prevented increases in the expression of mesenchymal markers as well as TGF-β1, ROCK1, collagen I and III. Furthermore, Ac-SDKP treatment prevented decreases in the expression of epithelial cell markers in both in vivo and in vitro experiments. Based on the results, we conclude that Ac-SDKP inhibits the transition of epithelial cell-myofibroblast in silicosis via activation of the TGF-β1/ROCK1 signaling pathway, which may serve as a novel mechanism by which it exerts its anti-fibrosis properties.

  17. Protective effect of Ac-SDKP on alveolar epithelial cells through inhibition of EMT via TGF-β1/ROCK1 pathway in silicosis in rat.

    Science.gov (United States)

    Deng, Haijing; Xu, Hong; Zhang, Xianghong; Sun, Yue; Wang, Ruimin; Brann, Darrell; Yang, Fang

    2016-03-01

    The epithelial-mesenchymal transition (EMT) is a critical stage during the development of silicosis fibrosis. In the current study, we hypothesized that the anti-fibrotic tetrapeptide, N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP) may exert its anti-fibrotic effects via activation of the TGF-β1/ROCK1 pathway, leading to inhibition of EMT. To address this hypothesis, we first examined the effect of Ac-SDKP upon EMT using an in vivo rat silicosis model, as well as in an in vitro model of TGF-β1-induced EMT. Confocal laser scanning microscopy was used to examine colocalization of surfactant protein A (SP-A), fibroblast specific protein-1 (FSP-1) and α-smooth muscle actin (α-SMA) in vivo. Western blot analysis was used to examine for changes in the protein levels of E-cadherin (E-cad) and SP-A (epithelial cell markers), vimentin (mesenchymal cell marker), α-SMA (active myofibroblast marker), and collagen I and III in both in vivo and in vitro experiments. Secondly, we utilized Western blot analysis and confocal laser scanning microscopy to examine the protein expression of TGF-β1 and ROCK1 in in vivo and in vitro studies. The results revealed that Ac-SDKP treatment prevented increases in the expression of mesenchymal markers as well as TGF-β1, ROCK1, collagen I and III. Furthermore, Ac-SDKP treatment prevented decreases in the expression of epithelial cell markers in both in vivo and in vitro experiments. Based on the results, we conclude that Ac-SDKP inhibits the transition of epithelial cell-myofibroblast in silicosis via activation of the TGF-β1/ROCK1 signaling pathway, which may serve as a novel mechanism by which it exerts its anti-fibrosis properties. PMID:26785300

  18. Rock Paintings.

    Science.gov (United States)

    Jones, Julienne Edwards

    1998-01-01

    Discusses the integration of art and academics in a fifth-grade instructional unit on Native American culture. Describes how students studied Native American pictographs, designed their own pictographs, made their own tools, and created rock paintings of their pictographs using these tools. Provides a list of references on Native American…

  19. Intellektuaalne rock

    Index Scriptorium Estoniae

    2007-01-01

    Briti laulja-helilooja ja näitleja Toyah Willcox ning Bill Rieflin ansamblist R.E.M. ja Pat Mastelotto King Krimsonist esinevad koos ansamblitega The Humans ja Tuner 25. okt. Tallinnas Rock Cafés ja 27. okt Tartu Jaani kirikus

  20. Oil-slick instability near an oil boom: The influence of free-slip and exact free-surface conditions

    International Nuclear Information System (INIS)

    In the event of an oil spill, oil booms are often used to contain the oil before attempting to skim the oil by using oil-skimmers. Under certain conditions, the oil droplets can leave the oil slick and enter the water. A simple balance of hydrodynamic forces on such a droplet results in an instability criterion which determines whether the droplets will be swept past the boom or not. This criterion depends on the pressure gradient along the boom. In this study, the solution of viscous flow past an oil boom problem by the fractional-step method in a curvilinear coordinate system is used to calculate the pressure gradient and to study the effectiveness of oil-containment by booms. The influence of approximate free-surface conditions, such as rigid-lid no-slip, rigid-lid free-slip, and the exact free-surface condition on the instability criterion is investigated

  1. Regulation of ROCK Activity in Cancer

    DEFF Research Database (Denmark)

    Morgan-Fisher, Marie; Wewer, Ulla M; Yoneda, Atsuko

    2013-01-01

    , these findings demonstrate additional modes to regulate ROCK activity. This review describes the molecular mechanisms of ROCK activity regulation in cancer, with emphasis on ROCK isoform-specific regulation and interaction partners, and discusses the potential of ROCKs as therapeutic targets in cancer.......Cancer-associated changes in cellular behavior, such as modified cell-cell contact, increased migratory potential, and generation of cellular force, all require alteration of the cytoskeleton. Two homologous mammalian serine/threonine kinases, Rho-associated protein kinases (ROCK I and II), are key...... regulators of the actin cytoskeleton acting downstream of the small GTPase Rho. ROCK is associated with cancer progression, and ROCK protein expression is elevated in several types of cancer. ROCKs exist in a closed, inactive conformation under quiescent conditions, which is changed to an open, active...

  2. Cooperative anti-invasive effect of Cdc42/Rac1 activation and ROCK inhibition in SW620 colorectal cancer cells with elevated blebbing activity.

    Directory of Open Access Journals (Sweden)

    Marion de Toledo

    Full Text Available Rho GTPases are key regulators of tumour cell invasion and therefore constitute attractive targets for the design of anticancer agents. Several strategies have been developed to modulate their increased activities during cancer progression. Interestingly, none of these approaches took into account the existence of the well-known antagonistic relationship between RhoA and Rac1. In this study, we first compared the invasiveness of a collection of colorectal cancer cell lines with their RhoA, Rac1 and Cdc42 activities. A marked decrease of active Cdc42 and Rac1 correlated with the high invasive potential of the cell lines established from metastatic sites of colorectal adenocarcinoma (LoVo, SKCo1, SW620 and CoLo205. Conversely, no correlation between RhoA activity and invasiveness was detected, whereas the activity of its kinase effector ROCK was higher in cancer cell lines with a more invasive phenotype. In addition, invasiveness in these colon cancer cell lines was correlated with a typical round and blebbing morphology. We then tested whether treatment with PDGF to restore Cdc42 and Rac1 activities and/or with Y27632, a chemical inhibitor of ROCK, could decrease the invasiveness of SW620 cells. The association of both treatments substantially decreased the invasive potential of SW620 cells and this effect was accompanied by loss of membrane blebbing, restoration of a more elongated cell morphology and re-establishment of E-cadherin-dependent adherens junctions. This study paves the road to the development of therapeutic strategies in which different Rho GTPase modulators are combined to modulate the cross-talk between Rho GTPases and their specific input in metastatic progression.

  3. Self-Assembled Tetrahedral DNA Nanostructures Promote Adipose-Derived Stem Cell Migration via lncRNA XLOC 010623 and RHOA/ROCK2 Signal Pathway.

    Science.gov (United States)

    Shi, Sirong; Peng, Qiang; Shao, Xiaoru; Xie, Jing; Lin, Shiyu; Zhang, Tao; Li, Qianshun; Li, Xiaolong; Lin, Yunfeng

    2016-08-01

    Self-assembled tetrahedral DNA nanostructures (TDNs) with precise sizes have been extensively applied in various fields owing to their exceptional mechanical rigidity, structural stability, and modification versatility. In addition, TDNs can be internalized by mammalian cells and remain mainly intact within the cytoplasm by escaping degradation by nucleases. Here, we studied the effects of TDNs on cell migration and the underlying molecular mechanisms. TDNs remarkably enhanced the migration of rat adipose-derived stem cells and down-regulated the long noncoding RNA (lncRNA) XLOC 010623 to activate the mRNA expression of Tiam1 and Rac1. Furthermore, TDNs highly up-regulated the mRNA and protein expression of RHOA, ROCK2, and VCL. These results indicate that TDNs suppressed the transcription of lncRNA XLOC 010623 and activated the TIAM1/RAC1 and RHOA/ROCK2 signaling pathways to promote cell migration. On the basis of these findings, TDNs show a high potential for application in tissue repair and regenerative medicine as a functional three-dimensional DNA nanomaterial. PMID:27403707

  4. Diavik Waste Rock Project: Evolution of Mineral Weathering, Element Release, and Acid Generation and Neutralization during a Five-Year Humidity Cell Experiment

    Directory of Open Access Journals (Sweden)

    Jeff B. Langman

    2014-04-01

    Full Text Available A five-year, humidity-cell experiment was used to study the weathering evolution of a low-sulfide, granitic waste rock at 5 and 22 °C. Only the rock with the highest sulfide content (0.16 wt % released sufficient acid to overcome a limited carbonate acid-neutralization capacity and produce a substantial decline in pH. Leached SO4 and Ca quickly increased then decreased during the first two years of weathering. Sulfide oxidation continued to release acid and SO4 after carbonate depletion, resulting in an increase in acid-soluble elements, including Cu and Zn. With the dissolution of Al-bearing minerals, the pH stabilized above 4, and sulfide oxidation continued to decline until the end of the experiment. The variation in activation energy of sulfide oxidation correlates with changes in sulfide availability, where the lowest activation energies occurred during the largest releases of SO4. A decrease in sulfide availability was attributed to consumption of sulfide and weathered rims on sulfide grains that reduced the oxidation rate. Varying element release rates due to changing carbonate and sulfide availability provide identifiable geochemical conditions that can be viewed as neutralization sequences and may be extrapolated to the field site for examining the evolution of mineral weathering of the waste rock.

  5. Analysis of the contribution of wind drift factor to oil slick movement under strong tidal condition: Hebei Spirit oil spill case.

    Directory of Open Access Journals (Sweden)

    Tae-Ho Kim

    Full Text Available The purpose of this study is to investigate the effects of the wind drift factor under strong tidal conditions in the western coastal area of Korea on the movement of oil slicks caused by the Hebei Spirit oil spill accident in 2007. The movement of oil slicks was computed using a simple simulation model based on the empirical formula as a function of surface current, wind speed, and the wind drift factor. For the simulation, the Environmental Fluid Dynamics Code (EFDC model and Automatic Weather System (AWS were used to generate tidal and wind fields respectively. Simulation results were then compared with 5 sets of spaceborne optical and synthetic aperture radar (SAR data. From the present study, it was found that highest matching rate between the simulation results and satellite imagery was obtained with different values of the wind drift factor, and to first order, this factor was linearly proportional to the wind speed. Based on the results, a new modified empirical formula was proposed for forecasting the movement of oil slicks on the coastal area.

  6. Water - rock interaction in different rock environments

    International Nuclear Information System (INIS)

    The study assesses the groundwater geochemistry and geological environment of 44 study sites for radioactive waste disposal. Initially, the study sites were divided by rock type into 5 groups: (1) acid - intermediate rocks, (2) mafic - ultramafic rocks, (3) gabbros, amphibolites and gneisses that contain calc-silicate (skarn) rocks, (4) carbonates and (5) sandstones. Separate assessments are made of acid - intermediate plutonic rocks and of a subgroup that comprises migmatites, granite and mica gneiss. These all belong to the group of acid - intermediate rocks. Within the mafic -ultramafic rock group, a subgroup that comprises mafic - ultramafic plutonic rocks, serpentinites, mafic - ultramafic volcanic rocks and volcanic - sedimentary schists is also evaluated separately. Bedrock groundwaters are classified by their concentration of total dissolved solids as fresh, brackish, saline, strongly saline and brine-class groundwaters. (75 refs., 24 figs., 3 tabs.)

  7. CERN Rocks

    CERN Multimedia

    2004-01-01

    The 15th CERN Hardronic Festival took place on 17 July on the terrace of Rest 3 (Prévessin). Over 1000 people, from CERN and other International Organizations, came to enjoy the warm summer night, and to watch the best of the World's High Energy music. Jazz, rock, pop, country, metal, blues, funk and punk blasted out from 9 bands from the CERN Musiclub and Jazz club, alternating on two stages in a non-stop show.  The night reached its hottest point when The Canettes Blues Band got everybody dancing to sixties R&B tunes (pictured). Meanwhile, the bars and food vans were working at full capacity, under the expert management of the CERN Softball club, who were at the same time running a Softball tournament in the adjacent "Higgs Field". The Hardronic Festival is the main yearly CERN music event, and it is organized with the support of the Staff Association and the CERN Administration.

  8. Testing the Generalization Efficiency of Oil Slick Classification Algorithm Using Multiple SAR Data for Deepwater Horizon Oil Spill

    Science.gov (United States)

    Ozkan, C.; Osmanoglu, B.; Sunar, F.; Staples, G.; Kalkan, K.; Balık Sanlı, F.

    2012-07-01

    Marine oil spills due to releases of crude oil from tankers, offshore platforms, drilling rigs and wells, etc. are seriously affecting the fragile marine and coastal ecosystem and cause political and environmental concern. A catastrophic explosion and subsequent fire in the Deepwater Horizon oil platform caused the platform to burn and sink, and oil leaked continuously between April 20th and July 15th of 2010, releasing about 780,000 m3 of crude oil into the Gulf of Mexico. Today, space-borne SAR sensors are extensively used for the detection of oil spills in the marine environment, as they are independent from sun light, not affected by cloudiness, and more cost-effective than air patrolling due to covering large areas. In this study, generalization extent of an object based classification algorithm was tested for oil spill detection using multiple SAR imagery data. Among many geometrical, physical and textural features, some more distinctive ones were selected to distinguish oil and look alike objects from each others. The tested classifier was constructed from a Multilayer Perception Artificial Neural Network trained by ABC, LM and BP optimization algorithms. The training data to train the classifier were constituted from SAR data consisting of oil spill originated from Lebanon in 2007. The classifier was then applied to the Deepwater Horizon oil spill data in the Gulf of Mexico on RADARSAT-2 and ALOS PALSAR images to demonstrate the generalization efficiency of oil slick classification algorithm.

  9. Bone Morphogenetic Protein-2-Induced Signaling and Osteogenesis Is Regulated by Cell Shape, RhoA/ROCK, and Cytoskeletal Tension

    OpenAIRE

    Wang, Yang-Kao; Yu, Xiang; Cohen, Daniel M.; Wozniak, Michele A.; Yang, Michael T.; Gao, Lin; Eyckmans, Jeroen; Chen, Christopher S.

    2011-01-01

    Osteogenic differentiation of human mesenchymal stem cells (hMSCs) is classically thought to be mediated by different cytokines such as the bone morphogenetic proteins (BMPs). Here, we report that cell adhesion to extracellular matrix (ECM), and its effects on cell shape and cytoskeletal mechanics, regulates BMP-induced signaling and osteogenic differentiation of hMSCs. Using micropatterned substrates to progressively restrict cell spreading and flattening against ECM, we demonstrated that BM...

  10. Intercellular Adhesion-Dependent Cell Survival and ROCK-Regulated Actomyosin-Driven Forces Mediate Self-Formation of a Retinal Organoid

    Directory of Open Access Journals (Sweden)

    Albert Lowe

    2016-05-01

    Full Text Available In this study we dissected retinal organoid morphogenesis in human embryonic stem cell (hESC-derived cultures and established a convenient method for isolating large quantities of retinal organoids for modeling human retinal development and disease. Epithelialized cysts were generated via floating culture of clumps of Matrigel/hESCs. Upon spontaneous attachment and spreading of the cysts, patterned retinal monolayers with tight junctions formed. Dispase-mediated detachment of the monolayers and subsequent floating culture led to self-formation of retinal organoids comprising patterned neuroretina, ciliary margin, and retinal pigment epithelium. Intercellular adhesion-dependent cell survival and ROCK-regulated actomyosin-driven forces are required for the self-organization. Our data supports a hypothesis that newly specified neuroretina progenitors form characteristic structures in equilibrium through minimization of cell surface tension. In long-term culture, the retinal organoids autonomously generated stratified retinal tissues, including photoreceptors with ultrastructure of outer segments. Our system requires minimal manual manipulation, has been validated in two lines of human pluripotent stem cells, and provides insight into optic cup invagination in vivo.

  11. AB250. Annexin V-induced rat Leydig cell proliferation involves Ect2 via RhoA/ROCK signaling pathway

    OpenAIRE

    Yao, Bin

    2016-01-01

    Background This study investigated the effect of annexin V on the proliferation of primary rat Leydig cells and the potential mechanism. Methods The primary rat Leydig cells were cultured in vitro and treated with 1 nmol/L annexin 5 and with siRNA–Ect2 transfection. The cell proliferation rate was measured by MTT assay. Phase distribution of cell cycle was analyzed by flow cytometry. The expression of Ect2 in protein level were detected by western blotting. RhoA activity was measured by Rho a...

  12. Virion Glycoprotein-Mediated Immune Evasion by Human Cytomegalovirus: a Sticky Virus Makes a Slick Getaway.

    Science.gov (United States)

    Gardner, Thomas J; Tortorella, Domenico

    2016-09-01

    The prototypic herpesvirus human cytomegalovirus (CMV) exhibits the extraordinary ability to establish latency and maintain a chronic infection throughout the life of its human host. This is even more remarkable considering the robust adaptive immune response elicited by infection and reactivation from latency. In addition to the ability of CMV to exist in a quiescent latent state, its persistence is enabled by a large repertoire of viral proteins that subvert immune defense mechanisms, such as NK cell activation and major histocompatibility complex antigen presentation, within the cell. However, dissemination outside the cell presents a unique existential challenge to the CMV virion, which is studded with antigenic glycoprotein complexes targeted by a potent neutralizing antibody response. The CMV virion envelope proteins, which are critical mediators of cell attachment and entry, possess various characteristics that can mitigate the humoral immune response and prevent viral clearance. Here we review the CMV glycoprotein complexes crucial for cell attachment and entry and propose inherent properties of these proteins involved in evading the CMV humoral immune response. These include viral glycoprotein polymorphism, epitope competition, Fc receptor-mediated endocytosis, glycan shielding, and cell-to-cell spread. The consequences of CMV virion glycoprotein-mediated immune evasion have a major impact on persistence of the virus in the population, and a comprehensive understanding of these evasion strategies will assist in designing effective CMV biologics and vaccines to limit CMV-associated disease. PMID:27307580

  13. 溶血磷脂酸调控RhoA/ROCK2信号通路对乳腺癌细胞增殖的影响%Influence of lysophosphatidic acid on proliferation of breast cancer cell by adjusted RhoA/ROCK2 signal pathway

    Institute of Scientific and Technical Information of China (English)

    许海; 段刚峰

    2013-01-01

    目的 探讨溶血磷脂酸(LPA)与RhoA/ROCK2信号通路对乳腺癌细胞增殖的影响及其作用机制.方法 以不同浓度LPA干预乳腺癌MDA-MB-231细胞,每隔24 h以细胞计数法观察和记录细胞的增殖.以最佳LPA促增殖浓度作用于MDA-MB-231细胞,观察Rho激酶抑制剂(Y-27632)对癌细胞的影响;以Pull-down及Western blot法检测各组细胞内RhoA活性及RhoA、ROCK2蛋白表达.结果 LPA以时间及剂量依赖性关系显著促进MDA-MB-231细胞的增殖(P<0.05);Y-27632可以显著抑制LPA的促增殖作用;LPA干预后RhoA活性及RhoA、ROCK2蛋白表达显著升高(P<0.05),Y-27632干预后RhoA活性及RhoA、ROCK2蛋白表达显著下降(P<0.05).结论 LPA可能通过调控RhoA/ROCK2信号通路促进乳腺癌细胞的增殖,为乳腺癌的临床治疗提供了新思路.%Objective To investigate the influence and mechanism of lysophosphatidic acid and RhoA/ROCK2 signal pathway on proliferation of breast cancer cell. Methods After treatment with different concentration of LPA, the proliferation of breast cancer cell MDA-MB-231 was observed and recorded by cell count method every of 24 h. MDA-MB-231 treated with optimal concentration of LPA and observed the effect of Rho kinase inhibitor( Y-27632) on LPA-induced proliferation. The activity of RhoA was tested by a pull-down way. The protein expression of RhoA and ROCK2 were determined by Western blot. Results LPA could promote MDA-MB-231 proliferation in a time and dose-dependent manner (P 〈 0. 05). ROCK inhibitor significantly inhibited LPA-induced cell proliferation (P 〈 0. 05 ). The activity of RhoA and expressionof RhoA, ROCK2 were enhanced significantly after LPA intervention (P 〈0. 05). However Y-27632 markedly decreased LPA-induced the increase of RhoA activity and protein expression of RhoA and ROCK2 ( P 〈 0. 05). Conclusions LPA may promote breast cancer cell proliferation through regulating RhoA/ROCK2 signal pathway. It provides a new idea

  14. Determination of the thermal efficiency of pre-boilover burning of a slick of oil on water

    International Nuclear Information System (INIS)

    The burning rate of a slick of oil on a water bed is calculated by a simple expression derived from a one dimensional heat conduction equation. Heat feedback from the flame to the surface is assumed to be a constant fraction of the total energy released by the combustion reaction. The constant fraction (χ) is named the burning efficiency and represent an important tool in assessing the potential of in situ burning as a counter-measure to an oil-spill. The total heat release, as a function of the pool diameter, is obtained from an existing correlation. It is assumed that radiative heat is absorbed close to the fuel surface, that conduction is the dominant mode of heat transfer in the liquid phase and that the fuel boil temperature remains constant. By matching the characteristic thermal penetration length scale for the fuel/water systems and an equivalent single layer system, a combined thermal diffusivity can be calculated and used to obtain an analytical solution for the burning rate. Theoretical expressions were correlate with crude oil and heating oil, for a number of pool diameters and initial fuel layer thickness. Experiments were also conducted with emulsified and weathered crude oil. The simple analytical expression describes well the effects of pool diameter and initial fuel layer thickness permitting a better observation of the effects of weathering, emulsification and net heat feedback to the fuel surface. Experiments showed that only a small fraction of the heat released by the flame is retained by the fuel layer and water bed (of the order of 1%). The effect of weathering on the burning rate decreases with the weathering period and that emulsification results in a linear decrease of the burning rate with water content. (Author)

  15. Traction force microscopy in rapidly moving cells reveals separate roles for ROCK and MLCK in the mechanics of retraction.

    Science.gov (United States)

    Morin, Timothy R; Ghassem-Zadeh, Sean A; Lee, Juliet

    2014-08-15

    Retraction is a major rate-limiting step in cell motility, particularly in slow moving cell types that form large stable adhesions. Myosin II dependent contractile forces are thought to facilitate detachment by physically pulling up the rear edge. However, retraction can occur in the absence of myosin II activity in cell types that form small labile adhesions. To investigate the role of contractile force generation in retraction, we performed traction force microscopy during the movement of fish epithelial keratocytes. By correlating changes in local traction stress at the rear with the area retracted, we identified four distinct modes of retraction. "Recoil" retractions are preceded by a rise in local traction stress, while rear edge is temporarily stuck, followed by a sharp drop in traction stress upon detachment. This retraction type was most common in cells generating high average traction stress. In "pull" type retractions local traction stress and area retracted increase concomitantly. This was the predominant type of retraction in keratocytes and was observed mostly in cells generating low average traction stress. "Continuous" type retractions occur without any detectable change in traction stress, and are seen in cells generating low average traction stress. In contrast, to many other cell types, "release" type retractions occur in keratocytes following a decrease in local traction stress. Our identification of distinct modes of retraction suggests that contractile forces may play different roles in detachment that are related to rear adhesion strength. To determine how the regulation of contractility via MLCK or Rho kinase contributes to the mechanics of detachment, inhibitors were used to block or augment these pathways. Modulation of MLCK activity led to the most rapid change in local traction stress suggesting its importance in regulating attachment strength. Surprisingly, Rho kinase was not required for detachment, but was essential for localizing

  16. THE INVESTIGATION ON INTERFACE CHARACTERISTIC OF CERAMIC SEALANTS PRODUCED FROM NATURAL ROCKS FOR SOLID OXIDE FUEL CELLS

    OpenAIRE

    Çiçekli, A Elif; ERCENK, Ediz; Yılmaz, Şenol

    2015-01-01

    Solid oxide fuel cells (SOFC), which are green electrochemical devices, transform directly chemical energy of fuel to electricity, and striking heat energy by using solid fuels as electrolyte [1-3].One of the essential problems for SOFC is to mix the gases, which used in anode and cathode, reacting electrochemically at high temperature before the reaction and/or the gas infiltration to outside of SOFC. It makes security problem and low efficiency. To use safe sealing material for SOFC is very...

  17. A Laboratory Shear Cell Used for Simulation of Shear Strength and Asperity Degradation of Rough Rock Fractures

    Science.gov (United States)

    Asadi, M. S.; Rasouli, V.; Barla, G.

    2013-07-01

    Different failure modes during fracture shearing have been introduced including dilation, sliding, asperity cut-off and degradation. Several laboratory studies have reported the complexity of these failure modes during shear tests performed under either constant normal load (CNL) or constant normal stiffness (CNS) conditions. This paper is concerned with the mechanical behaviour of synthetic fractures during direct shear tests using a modified shear cell and related numerical simulation studies. The modifications made to an existing true triaxial stress cell (TTSC) in order to use it for performing shear tests under CNL conditions are presented. The large loading capacity and the use of accurate hydraulic pumps capable of applying a constant shear velocity are the main elements of this cell. Synthetic mortar specimens with different fracture surface geometries are tested to study the failure modes, including fracture sliding, asperity degradation, and to understand failure during shearing. A bonded particle model of the direct shear test with the PFC2D particle flow code is used to mimic the tests performed. The results of a number of tests are presented and compared with PFC2D simulations. The satisfactory results obtained both qualitatively and quantitatively are discussed.

  18. Mechanical stimulation of cyclic tensile strain induces reduction of pluripotent related gene expressions via activation of Rho/ROCK and subsequent decreasing of AKT phosphorylation in human induced pluripotent stem cells

    Energy Technology Data Exchange (ETDEWEB)

    Teramura, Takeshi, E-mail: teramura@med.kindai.ac.jp [Institute of Advanced Clinical Medicine, Kinki University, Faculty of Medicine, Osaka (Japan); Takehara, Toshiyuki; Onodera, Yuta [Institute of Advanced Clinical Medicine, Kinki University, Faculty of Medicine, Osaka (Japan); Nakagawa, Koichi; Hamanishi, Chiaki [Department of Orthopaedic Surgery, Kinki University, Faculty of Medicine, Osaka (Japan); Fukuda, Kanji [Institute of Advanced Clinical Medicine, Kinki University, Faculty of Medicine, Osaka (Japan); Department of Orthopaedic Surgery, Kinki University, Faculty of Medicine, Osaka (Japan)

    2012-01-13

    Highlights: Black-Right-Pointing-Pointer Mechanical stimulation is an important factor for regulation of stem cell fate. Black-Right-Pointing-Pointer Cyclic stretch to human induced pluripotent stem cells activated small GTPase Rho. Black-Right-Pointing-Pointer Rho-kinase activation attenuated pluripotency via inhibition of AKT activation. Black-Right-Pointing-Pointer This reaction could be reproduced only by transfection of dominant active Rho. Black-Right-Pointing-Pointer Rho/ROCK are important molecules in mechanotransduction and control of stemness. -- Abstract: Mechanical stimulation has been shown to regulate the proliferation and differentiation of stem cells. However, the effects of the mechanical stress on the stemness or related molecular mechanisms have not been well determined. Pluripotent stem cells such as embryonic stem (ES) cells and induced pluripotent stem (iPS) cells are used as good materials for cell transplantation therapy and research of mammalian development, since they can self-renew infinitely and differentiate into various cell lineages. Here we demonstrated that the mechanical stimulation to human iPS cells altered alignment of actin fibers and expressions of the pluripotent related genes Nanog, POU5f1 and Sox2. In the mechanically stimulated iPS cells, small GTPase Rho was activated and interestingly, AKT phosphorylation was decreased. Inhibition of Rho-associated kinase ROCK recovered the AKT phosphorylation and the gene expressions. These results clearly suggested that the Rho/ROCK is a potent primary effector of mechanical stress in the pluripotent stem cells and it participates to pluripotency-related signaling cascades as an upper stream regulator.

  19. My Pet Rock

    Science.gov (United States)

    Lark, Adam; Kramp, Robyne; Nurnberger-Haag, Julie

    2008-01-01

    Many teachers and students have experienced the classic pet rock experiment in conjunction with a geology unit. A teacher has students bring in a "pet" rock found outside of school, and the students run geologic tests on the rock. The tests include determining relative hardness using Mohs scale, checking for magnetization, and assessing luster.…

  20. The rock diet

    OpenAIRE

    Fordyce, Fiona; Johnson, Chris

    2002-01-01

    You may think there is little connection between rocks and our diet, indeed a serving of rocks may sound very unappetising! But rocks are a vital source of the essential elements and minerals we need to keep us healthy, such as calcium for healthy teeth and bones.

  1. Composición de zooplancton superficial en zonas lisas y rugosas en la bahía de Coquimbo (noviembre 2001 Surface zooplankton composition in slick and rough zones in Coquimbo Bay (November 2001

    Directory of Open Access Journals (Sweden)

    Humberto Mattos

    2012-07-01

    Full Text Available Se comparó la abundancia de zooplancton superficial, temperatura superficial del mar e intensidad del viento entre zonas lisas y rugosas en el sector sur de la bahía de Coquimbo, entre el 7 y 9 de noviembre de 2001. La presencia de superficies lisas y rugosas estuvo influenciada por la intensidad del viento y desaparece cuando supera 6 m s-1 en forma sostenida. La temperatura en los dos primeros días de muestreo fue diferente entre los dos tipos de superficie. El último día la temperatura fue mayor, sin diferencias entre ambos tipos de superficies y con mayor profundidad de la capa de mezcla, debido al aumento de la intensidad del viento. En los dos primeros días, la mayoría de los grupos zooplanctónicos tuvieron abundancias mayores en las superficies lisas, observándose diferencias significativas entre zonas lisas y rugosas en las larvas cypris de cirripedios y en el eufáusido Nyctiphanes simplex. Se estableció que los zooplancteres capturados, tienden a agregarse en superficies lisas o rugosas, dependiendo de sus características adaptativas y de su comportamiento.The surface zooplankton abundances, sea surface temperature and wind speed in slick and rough surface areas were compared south of Coquimbo Bay on November 7, 8 and 9, 2001. The presence of rough and slick surfaces on the bay was influenced by the wind conditions during sampling hours, demonstrating that increasing the speed steadily over 6 m s-1 slick and rough areas disappeared, giving a ripple appearance to sea surface. On the first two days of study, thermal structure of slicks areas was different from the rough ones. On the last day, temperature was higher with no differences between both surfaces types, and greater depth of the mixed layer, due to increasing wind speed. The organisms captured were holoplanktonic crustaceans, meroplankton benthopelagic peracarids, fish larvae and eggs, gelatinous zooplankton and gastropod and bivalve mollusks. On the first two days of

  2. A Val85Met mutation in melanocortin-1 receptor is associated with reductions in eumelanic pigmentation and cell surface expression in domestic rock pigeons (Columba livia.

    Directory of Open Access Journals (Sweden)

    Michael W Guernsey

    Full Text Available Variation in the melanocortin-1 receptor (Mc1r is associated with pigmentation diversity in wild and domesticated populations of vertebrates, including several species of birds. Among domestic bird species, pigmentation variation in the rock pigeon (Columbalivia is particularly diverse. To determine the potential contribution of Mc1r variants to pigment diversity in pigeons, we sequenced Mc1r in a wide range of pigeon breeds and identified several single nucleotide polymorphisms, including a variant that codes for an amino acid substitution (Val85Met. In contrast to the association between Val85Met and eumelanism in other avian species, this change was associated with pheomelanism in pigeons. In vitro cAMP accumulation and protein expression assays revealed that Val85Met leads to decreased receptor function and reduced cell surface expression of the mutant protein. The reduced in vitro function is consistent with the observed association with reduced eumelanic pigmentation. Comparative genetic and cellular studies provide important insights about the range of mechanisms underlying diversity among vertebrates, including different phenotypic associations with similar mutations in different species.

  3. Rock History and Culture

    OpenAIRE

    Gonzalez, Éric

    2013-01-01

    Two ambitious works written by French-speaking scholars tackle rock music as a research object, from different but complementary perspectives. Both are a definite must-read for anyone interested in the contextualisation of rock music in western popular culture. In Une histoire musicale du rock (i.e. A Musical History of Rock), rock music is approached from the point of view of the people – musicians and industry – behind the music. Christophe Pirenne endeavours to examine that field from a m...

  4. A quasi-exclusive European ancestry in the Senepol tropical cattle breed highlights the importance of the slick locus in tropical adaptation.

    Directory of Open Access Journals (Sweden)

    Laurence Flori

    Full Text Available BACKGROUND: The Senepol cattle breed (SEN was created in the early XX(th century from a presumed cross between a European (EUT breed (Red Poll and a West African taurine (AFT breed (N'Dama. Well adapted to tropical conditions, it is also believed trypanotolerant according to its putative AFT ancestry. However, such origins needed to be verified to define relevant husbandry practices and the genetic background underlying such adaptation needed to be characterized. METHODOLOGY/PRINCIPAL FINDINGS: We genotyped 153 SEN individuals on 47,365 SNPs and combined the resulting data with those available on 18 other populations representative of EUT, AFT and Zebu (ZEB cattle. We found on average 89% EUT, 10.4% ZEB and 0.6% AFT ancestries in the SEN genome. We further looked for footprints of recent selection using standard tests based on the extent of haplotype homozygosity. We underlined i three footprints on chromosome (BTA 01, two of which are within or close to the polled locus underlying the absence of horns and ii one footprint on BTA20 within the slick hair coat locus, involved in thermotolerance. Annotation of these regions allowed us to propose three candidate genes to explain the observed signals (TIAM1, GRIK1 and RAI14. CONCLUSIONS/SIGNIFICANCE: Our results do not support the accepted concept about the AFT origin of SEN breed. Initial AFT ancestry (if any might have been counter-selected in early generations due to breeding objectives oriented in particular toward meat production and hornless phenotype. Therefore, SEN animals are likely susceptible to African trypanosomes which questions the importation of SEN within the West African tsetse belt, as promoted by some breeding societies. Besides, our results revealed that SEN breed is predominantly a EUT breed well adapted to tropical conditions and confirmed the importance in thermotolerance of the slick locus.

  5. Hungry for Rocks

    Science.gov (United States)

    2004-01-01

    This image from the Mars Exploration Rover Spirit hazard identification camera shows the rover's perspective just before its first post-egress drive on Mars. On Sunday, the 15th martian day, or sol, of Spirit's journey, engineers drove Spirit approximately 3 meters (10 feet) toward its first rock target, a football-sized, mountain-shaped rock called Adirondack (not pictured). In the foreground of this image are 'Sashimi' and 'Sushi' - two rocks that scientists considered investigating first. Ultimately, these rocks were not chosen because their rough and dusty surfaces are ill-suited for grinding.

  6. Soft rocks in Argentina

    Institute of Scientific and Technical Information of China (English)

    Giambastiani; Mauricio

    2014-01-01

    Soft rocks are a still fairly unexplored chapter in rock mechanics. Within this category are the clastic sedimentary rocks and pyroclastic volcanic rocks, of low to moderate lithification (consolidation, cemen-tation, new formed minerals), chemical sedimentary rocks and metamorphic rocks formed by minerals with Mohs hardness less than 3.5, such as limestone, gypsum, halite, sylvite, between the first and phyllites, graphitic schist, chloritic shale, talc, etc., among the latter. They also include any type of rock that suffered alteration processes (hydrothermal or weathering). In Argentina the study of low-strength rocks has not received much attention despite having extensive outcrops in the Andes and great impact in the design criteria. Correlation between geomechanical properties (UCS, deformability) to physical index (porosity, density, etc.) has shown promising results to be better studied. There are many studies and engineering projects in Argentina in soft rock geological environments, some cited in the text (Chihuído dam, N. Kirchner dam, J. Cepernic Dam, etc.) and others such as International Tunnel in the Province of Mendoza (Corredor Bioceánico), which will require the valuable contribution from rock mechanics. The lack of consistency between some of the physical and mechanical parameters explored from studies in the country may be due to an insufficient amount of information and/or non-standardization of criteria for testing materials. It is understood that more and better academic and professional efforts in improv-ing techniques will result in benefits to the better understanding of the geomechanics of weak rocks.

  7. Influence of reactive oxygen species and RhoA/ROCK pathway on calcium concentration and calcium sensitivity of vascular smooth muscle cells%活性氧与 RhoA/ROCK 信号通路对血管平滑肌细胞钙浓度及钙敏感性的影响

    Institute of Scientific and Technical Information of China (English)

    闫莹; 杨朝; 汪涛

    2015-01-01

    Reactive oxygen species (ROS)is an important class of second messengers in vivo,and can be induced greatly by ischemia and hypoxia.Hypoxia signal can trigger the contraction of vascular smooth muscle cells by regulating the cytoplasmic free calcium concentration via ROS,hypoxia may also activate RhoA/ROCK signaling pathway by ROS and then regulate the calcium sensitivity.Deep research on ROS and RhoA/ROCK pathway will illustrate the pathogenesis of hypoxic pulmonary vasoconstriction and pulmonary hypertension,providing new ideas for the treatment of hypoxic pulmonary hypertension.%活性氧(ROS)是体内一类重要的第二信使,能在缺血缺氧的诱导下大量产生。缺氧信号能通过 ROS 调节血管平滑肌细胞内的钙浓度,从而引起其收缩反应;缺氧还有可能通过 ROS 激活 RhoA/ROCK 信号通路,对钙敏感性进行调节。对 ROS 以及 RhoA/ROCK 信号通路进行深入的研究,可以阐明缺氧性肺血管收缩以及肺动脉高压的发病机制,为缺氧性肺动脉高压的治疗提供新的思路。

  8. Space Weathering of Rocks

    Science.gov (United States)

    Noble, Sarah

    2011-01-01

    Space weathering discussions have generally centered around soils but exposed rocks will also incur the effects of weathering. On the Moon, rocks make up only a very small percentage of the exposed surface and areas where rocks are exposed, like central peaks, are often among the least space weathered regions we find in remote sensing data. However, our studies of weathered Ap 17 rocks 76015 and 76237 show that significant amounts of weathering products can build up on rock surfaces. Because rocks have much longer surface lifetimes than an individual soil grain, and thus record a longer history of exposure, we can study these products to gain a deeper perspective on the weathering process and better assess the relative impo!1ance of various weathering components on the Moon. In contrast to the lunar case, on small asteroids, like Itokowa, rocks make up a large fraction of the exposed surface. Results from the Hayabusa spacecraft at Itokowa suggest that while the low gravity does not allow for the development of a mature regolith, weathering patinas can and do develop on rock surfaces, in fact, the rocky surfaces were seen to be darker and appear spectrally more weathered than regions with finer materials. To explore how weathering of asteroidal rocks may differ from lunar, a set of ordinary chondrite meteorites (H, L, and LL) which have been subjected to artificial space weathering by nanopulse laser were examined by TEM. NpFe(sup 0) bearing glasses were ubiquitous in both the naturally-weathered lunar and the artificially-weathered meteorite samples.

  9. CRITERIA FOR ROCK ENGINEERING FAILURE

    Institute of Scientific and Technical Information of China (English)

    ZHUDeren; ZHANGYuzhuo

    1995-01-01

    A great number of underground rock projects are maintained in the rock mass which is subject to rock damage and failure development. In many cases, the rock. engineering is still under normal working conditions even though rock is already fails to some extent. This paper introduces two different concepts: rock failure and rock engineering failure. Rock failure is defined as a mechanical state under which an applicable characteristic is changed or lost.However, the rock engineering failure is an engineering state under which an applicable function is changed or lost. The failure of surrounding rocks is the major reason of rock engineering failure. The criterion of rock engineering failure depends on the limit of applicable functions. The rock engineering failure state possesses a corresponding point in rock failure state. In this paper, a description of rock engineering failure criterion is given by simply using a mechanical equation or expression. It is expected that the study of rock engineering failure criterion will be an optimal approach that combines research of rock mechanics with rock engineering problems.

  10. Rock kinoekraanil / Katrin Rajasaare

    Index Scriptorium Estoniae

    Rajasaare, Katrin

    2008-01-01

    7.-11. juulini kinos Sõprus toimuval filminädalal "Rock On Screen" ekraanile jõudvatest rockmuusikuid portreteerivatest filmidest "Lou Reed's Berlin", "The Future Is Unwritten: Joe Strummer", "Control: Joy Division", "Hurriganes", "Shlaager"

  11. Pop & rock / Berk Vaher

    Index Scriptorium Estoniae

    Vaher, Berk, 1975-

    2001-01-01

    Uute heliplaatide Redman "Malpractice", Brian Eno & Peter Schwalm "Popstars", Clawfinger "A Whole Lot of Nothing", Dario G "In Full Color", MLTR e. Michael Learns To Rock "Blue Night" lühitutvustused

  12. Folding at two different scales of the Paradox anticline in the Ordovician Cool Creek Formation, Arbuckle Group, Slick Hills, southwestern Oklahoma: A paleomagnetic fold test study.

    Science.gov (United States)

    Pannalal, S. J.; Zechmeister, M. S.; Elmore, D. R.

    2007-12-01

    The carbonates in the Cambro-Ordovician Arbuckle Group, part of the southern Oklahoma aulacogen, has been the subject of previous paleomagnetic studies with a focus primarily on their origin of the magnetizations. Most previous studies indicate late Paleozoic magnetizations that reside in hematite. However, Elmore et al. (1988) conducted a paleomagnetic study of the Arbuckle Group carbonates from the Slick Hills area utilizing six sites from a north-plunging tightly folded Paradox anticline. Alternating field and thermal demagnetization results from their study indicated a post-tilting remanence that resides primarily in magnetite. Also, based on the difference between the observed and expected remanence directions, they suggested a possible 30° block rotation. As a continuation of their work, this paleomagnetic study was conducted to corroborate the observed 30° rotations utilizing more sites from the Paradox anticline and the use of a more sensitive 2G Cryogenic magnetometer. In addition, the major focus of this paleomagnetic study is to examine the relationship between the timing of remanence acquisition with respect to the primary (F1) and the secondary (F2) folds of the Paradox anticline. To this extent, oriented samples of carbonates have been collected from the Ordovician Cool Creek Formation of the Paradox anticline from the Slick Hills area from both the F1 and the F2 folds. Low temperature demagnetization protocols have been carried out on these samples to remove the effects of multidomain magnetite grains thereby isolating better the characteristic remanence components. Post-low temperature cleaning, the thermal step-demagnetization procedure isolates primarily two components: 1.) a low-temperature steep downward viscous remanent magnetization; and, 2.) a high-temperature characteristic remanent magnetization component, residing primarily in magnetite, with shallow remanence directions scattered towards the east-south-east to south-east. Fold test

  13. Herpesvirus infections in rock hyraxes (Procavia capensis).

    Science.gov (United States)

    Galeota, Judith A; Napier, Julia E; Armstrong, Douglas L; Riethoven, Jean-Jack; Rogers, Douglas G

    2009-07-01

    Seven juveniles and 3 adults from a closed group of 19 rock hyraxes (Procavia capensis) housed in a zoo's indoor rock exhibit died or were euthanized after developing blepharoconjunctivitis and orofacial ulcers over a 2-week period. Histopathologic examination of dermal ulcers and ulcerated tongues revealed amphophilic to basophilic intranuclear inclusion bodies in epithelial cells bordering ulcers. Epithelial cells with inclusion bodies were often characterized by cytomegaly and karyomegaly, and many cells had formed syncytia. Examination of inclusion bodies in tongue epithelium by transmission electron microscopy revealed icosahedral nucleocapsids, approximately 80-95 nm in diameter, with morphologic features consistent with herpesvirus. Cytopathic effect (CPE) typical of alphaherpesvirus infection was seen in bovine turbinate, equine dermal, and Vero cell monolayers after inoculation with homogenates of the skin lesions, but CPE was not seen after inoculation onto Madin-Darby canine kidney or swine testicle cell monolayers. Polymerase chain reaction analysis using degenerate primers that targeted a portion of the herpesvirus polymerase gene generated a product of approximately 227 base pairs. The product was cloned, sequenced, and then analyzed using BLAST. At the nucleotide level, there was 86%, 77%, and 76% shared identity with Eidolon herpesvirus 1, Human herpesviruses 1 and 2, and Cercopithecine herpesvirus 2, respectively. Herpesvirus infections in rock hyraxes have not been characterized. The data presented in the current study suggest that a novel alphaherpesvirus caused the lesions seen in these rock hyraxes. The molecular characteristics of this virus would tentatively support its inclusion in the genus Simplexvirus.

  14. Groundwater in granitic rocks

    International Nuclear Information System (INIS)

    A comparison of published chemical analyses of ground waters found in granitic rocks from a variety of locations shows that their compositions fall into two distinct classes. Ground waters from shallow wells and springs have a high bicarbonate/chloride ratio resulting from the neutralization of carbonic acid (dissolved CO2) by weathering reactions. The sodium, potassium, and silica released by weathering reactions drive the solutions away from equilibrium with the dominant minerals in the granites (i.e., quartz, muscovite, potassium feldspar, and albite). On the other hand, ground waters from deep wells and excavations are rich in chloride relative to bicarbonate. Their Na, K, H, and silica activities indicate that they are nearly equilibrated with the granite minerals suggesting a very long residence time in the host rock. These observations furnish the basis for a powerful tool to aid in selecting sites for radioactive waste disposal in granitic rocks. When water-bearing fractures are encountered in these rocks, a chemical analysis of the solutions contained within the fracture can determine whether the water came from the surface, i.e., is bicarbonate rich and not equilibrated, or whether it is some sort of connate water that has resided in the rock for a long period, i.e., chloride rich and equilibrated. This technique should allow immediate recognition of fracture systems in granitic radioactive waste repositories that would allow radionuclides to escape to the surface

  15. O-Cell桩基承载力试验法在大直径超长钻孔嵌岩桩的应用%O-Cell Load Test for Rock-Socket Bored Piles with Large Diameter and Extra Length

    Institute of Scientific and Technical Information of China (English)

    刘亚东; 李胜; 史炳峰

    2012-01-01

    结合某桥梁大直径超长钻孔嵌岩桩承载力测试的实践,介绍了O-Cell桩基承载力试验原理和单桩极限承载力确定方法,对于荷载箱位置的选取及超长嵌岩桩成孔成桩工艺进行分析并提出自己的看法,为类似工程提供参考.%Based on the cumulative evidence of O-cell load test for rock-socket bored piles with large diameter and extra length for a bridge project, this paper introduces the theory of O-cell load test and the method of confirming the load. The positioning of loading equipment and the technology of boring and casting of long length rock-socket bored pile are also discussed and some views of the author are proposed to provide reference for similar projects.

  16. Rock mechanics research awards

    Science.gov (United States)

    Wagner, John E.

    The U.S. National Committee for Rock Mechanics, at its June 1983 annual meeting, adopted three actions to enhance the competition and public awareness of its annual awards program for rock mechanics papers. It will issue a call for nominations of outstanding papers; it will request participating societies to announce the names of award winners and the titles of papers, and it will publish an abstract of the winning papers in the proceedings of the annual U.S. Rock Mechanics Symposium in the year following the awards.The competition is open to papers, by U.S residents or students in a U.S. school, published in an English language publication normally available in the United States. The following authors and papers are the 1983 award winners:

  17. Experimental deformation of polyphase rock analogues

    NARCIS (Netherlands)

    Bons, P.D.

    1993-01-01

    This thesis presents an investigation into the mechanical properties of ductile polyphase materials, which were studied by a number of different techniques. The first approach was to do creep tests and transparent deformation cell experiments with two-phase composites of organic crystalline rock-ana

  18. Digital carbonate rock physics

    Science.gov (United States)

    Saenger, Erik H.; Vialle, Stephanie; Lebedev, Maxim; Uribe, David; Osorno, Maria; Duda, Mandy; Steeb, Holger

    2016-08-01

    Modern estimation of rock properties combines imaging with advanced numerical simulations, an approach known as digital rock physics (DRP). In this paper we suggest a specific segmentation procedure of X-ray micro-computed tomography data with two different resolutions in the µm range for two sets of carbonate rock samples. These carbonates were already characterized in detail in a previous laboratory study which we complement with nanoindentation experiments (for local elastic properties). In a first step a non-local mean filter is applied to the raw image data. We then apply different thresholds to identify pores and solid phases. Because of a non-neglectable amount of unresolved microporosity (micritic phase) we also define intermediate threshold values for distinct phases. Based on this segmentation we determine porosity-dependent values for effective P- and S-wave velocities as well as for the intrinsic permeability. For effective velocities we confirm an observed two-phase trend reported in another study using a different carbonate data set. As an upscaling approach we use this two-phase trend as an effective medium approach to estimate the porosity-dependent elastic properties of the micritic phase for the low-resolution images. The porosity measured in the laboratory is then used to predict the effective rock properties from the observed trends for a comparison with experimental data. The two-phase trend can be regarded as an upper bound for elastic properties; the use of the two-phase trend for low-resolution images led to a good estimate for a lower bound of effective elastic properties. Anisotropy is observed for some of the considered subvolumes, but seems to be insignificant for the analysed rocks at the DRP scale. Because of the complexity of carbonates we suggest using DRP as a complementary tool for rock characterization in addition to classical experimental methods.

  19. Rock engineering applications, 1991

    International Nuclear Information System (INIS)

    This book demonstrates how to apply the theories and principles of rock engineering to actual engineering and construction tasks. It features insights on geology for mining and tunnelling applications. It is practical resource that focuses on the latest technological innovation and examines up-to-date procedures used by engineers for coping with complex rock conditions. The authors also discuss question related to underground space, from design approaches to underground housing and storage. And they cover the monitoring of storage caverns for liquid and gaseous products or toxic and radioactive wastes

  20. Rock Hellsinki, Marketing Research

    OpenAIRE

    Todd, Roosa; Jalkanen, Katariina

    2013-01-01

    This paper is a qualitative research about rock and heavy metal music tourism in the capital city of Finland, Helsinki. As Helsinki can be considered the city of contrasts, the silent nature city mixed with urban activities, it is important to also use the potential of the loud rock and heavy metal music contrasting the silence. Finland is known abroad for bands such as HIM, Nightwish, Korpiklaani and Children of Bodom so it would make sense to utilize these in the tourism sector as well. The...

  1. Session: Hard Rock Penetration

    Energy Technology Data Exchange (ETDEWEB)

    Tennyson, George P. Jr.; Dunn, James C.; Drumheller, Douglas S.; Glowka, David A.; Lysne, Peter

    1992-01-01

    This session at the Geothermal Energy Program Review X: Geothermal Energy and the Utility Market consisted of five presentations: ''Hard Rock Penetration - Summary'' by George P. Tennyson, Jr.; ''Overview - Hard Rock Penetration'' by James C. Dunn; ''An Overview of Acoustic Telemetry'' by Douglas S. Drumheller; ''Lost Circulation Technology Development Status'' by David A. Glowka; ''Downhole Memory-Logging Tools'' by Peter Lysne.

  2. Rocking and Rolling Rattlebacks

    Science.gov (United States)

    Cross, Rod

    2013-01-01

    A rattleback is a well-known physics toy that has a preferred direction of rotation. If it is spun about a vertical axis in the "wrong" direction, it will slow down, start rocking from end to end, and then spin in the opposite (i.e. preferred) direction. Many articles have been written about rattlebacks. Some are highly mathematical and…

  3. Umhlanga Rocks coastal defense

    NARCIS (Netherlands)

    De Jong, L.; De Jong, B.; Ivanova, M.; Gerritse, A.; Rietberg, D.; Dorrepaal, S.

    2014-01-01

    The eThekwini coastline is a vulnerable coastline subject to chronic erosion and damage due to sea level rise. In 2007 a severe storm caused major physical and economic damage along the coastline, proving the need for action. Umhlanga Rocks is a densely populated premium holiday destination on the e

  4. Rock solid energy solution

    International Nuclear Information System (INIS)

    Scientists believe naturally radioactive rocks below the earth's surface could provide an inexhaustible and environmentally friendly power source. And Australia could be a geological hotbed should the concept get off the ground. Despite the scale, the concept itself is simple. The Earth's reserves of heat in naturally radioactive rocks could provide an effectively inexhaustible and environmentally friendly source of power. No greenhouse gas emissions, little water usage and minimal pollution. Natural hot springs are already used to make power in some parts of the world, such as Iceland, but creating artificial hot springs by drilling deep into granite -the hardest of rocks - is a much more ambitious concept. One cubic kilometre of hot granite at 250 deg C has the stored energy equivalent of 40 million barrels of oil. In a nutshell, water is pumped into the hot zone - some 3km to 5km down in Australian conditions - and spreads through a 'reservoir' of hot, cracked rocks. Once superheated, it returns to the surface as steam through a separate production well to spin turbines and generate electricity. The water can then be recaptured and reused, with test sites around the world recovering up to around 90 per cent

  5. Rock-hard coatings

    NARCIS (Netherlands)

    Muller, M.

    2007-01-01

    Aircraft jet engines have to be able to withstand infernal conditions. Extreme heat and bitter cold tax coatings to the limit. Materials expert Dr Ir. Wim Sloof fits atoms together to develop rock-hard coatings. The latest invention in this field is known as ceramic matrix composites. Sloof has sign

  6. Slippery Rock University

    Science.gov (United States)

    Arnhold, Robert W.

    2008-01-01

    Slippery Rock University (SRU), located in western Pennsylvania, is one of 14 state-owned institutions of higher education in Pennsylvania. The university has a rich tradition of providing professional preparation programs in special education, therapeutic recreation, physical education, and physical therapy for individuals with disabilities.…

  7. Adiponectin attenuates angiotensin II-induced vascular smooth muscle cell remodeling through nitric oxide and the RhoA/ROCK pathway.

    Directory of Open Access Journals (Sweden)

    Wared eNour-Eldine

    2016-04-01

    Full Text Available INTRODUCTION: Adiponectin (APN, an adipocytokine, exerts protective effects on cardiac remodeling, while angiotensin II (Ang II induces hypertension and vascular remodeling. The potential protective role of APN on the vasculature during hypertension has not been fully elucidated yet. Here, we evaluate the molecular mechanisms of the protective role of APN in the physiological response of the vascular wall to Ang II.METHODS AND RESULTS: Rat aortic tissues were used to investigate the effect of APN on Ang II-induced vascular remodeling and hypertrophy. We investigated whether nitric oxide (NO, the RhoA/ROCK pathway, actin cytoskeleton remodeling, and reactive oxygen species (ROS mediate the anti-hypertrophic effect of APN. Ang II-induced protein synthesis was attenuated by pre-treatment with APN, NO donor (SNAP, or cGMP. The hypertrophic response to Ang II was associated with a significant increase in RhoA activation and vascular force production, which were prevented by APN and SNAP. NO was also associated with inhibition of Ang II-induced phosphorylation of cofilin. In addition, immunohistochemistry revealed that 24 hr Ang II treatment increased the F- to G-actin ratio, an effect that was inhibited by SNAP. Ang II-induced ROS formation and upregulation of p22phox mRNA expression were inhibited by APN and NO. Both compounds failed to inhibit Nox1 and p47phox expression. CONCLUSIONS: Our results suggest that the anti-hypertrophic effects of APN are due, in part, to NO-dependent inhibition of the RhoA/ROCK pathway and ROS formation.

  8. Joint Commission on rock properties

    Science.gov (United States)

    A joint commission on Rock Properties for Petroleum Engineers (RPPE) has been established by the International Society of Rock Mechanics and the Society of Petroleum Engineers to set up data banks on the properties of sedimentary rocks encountered during drilling. Computer-based data banks of complete rock properties will be organized for sandstones (GRESA), shales (ARSHA) and carbonates (CARCA). The commission hopes to access data sources from members of the commission, private companies and the public domain.

  9. Phosphorylation and mRNA splicing of collapsin response mediator protein-2 determine inhibition of rho-associated protein kinase (ROCK) II function in carcinoma cell migration and invasion

    DEFF Research Database (Denmark)

    Morgan-Fisher, Marie; Couchman, John R; Yoneda, Atsuko

    2013-01-01

    The Rho-associated protein kinases (ROCK I and II) are central regulators of important cellular processes such as migration and invasion downstream of the GTP-Rho. Recently, we reported collapsin response mediator protein (CRMP)-2 as an endogenous ROCK II inhibitor. To reveal how the CRMP-2-ROCK II...

  10. Rock and mineral magnetism

    CERN Document Server

    O’Reilly, W

    1984-01-01

    The past two decades have witnessed a revolution in the earth sciences. The quantitative, instrument-based measurements and physical models of. geophysics, together with advances in technology, have radically transformed the way in which the Earth, and especially its crust, is described. The study of the magnetism of the rocks of the Earth's crust has played a major part in this transformation. Rocks, or more specifically their constituent magnetic minerals, can be regarded as a measuring instrument provided by nature, which can be employed in the service of the earth sciences. Thus magnetic minerals are a recording magnetometer; a goniometer or protractor, recording the directions of flows, fields and forces; a clock; a recording thermometer; a position recorder; astrain gauge; an instrument for geo­ logical surveying; a tracer in climatology and hydrology; a tool in petrology. No instrument is linear, or free from noise and systematic errors, and the performance of nature's instrument must be assessed and ...

  11. Uranium in alkaline rocks

    International Nuclear Information System (INIS)

    Geologic and geochemical criteria were developed for the occurrence of economic uranium deposits in alkaline igneous rocks. A literature search, a limited chemical analytical program, and visits to three prominent alkaline-rock localities (Ilimaussaq, Greenland; Pocos de Caldas, Brazil; and Powderhorn, Colorado) were made to establish criteria to determine if a site had some uranium resource potential. From the literature, four alkaline-intrusive occurrences of differing character were identified as type-localities for uranium mineralization, and the important aspects of these localities were described. These characteristics were used to categorize and evaluate U.S. occurrences. The literature search disclosed 69 U.S. sites, encompassing nepheline syenite, alkaline granite, and carbonatite. It was possible to compare two-thirds of these sites to the type localities. A ranking system identified ten of the sites as most likely to have uranium resource potential

  12. Uranium in alkaline rocks

    Energy Technology Data Exchange (ETDEWEB)

    Murphy, M.; Wollenberg, H.; Strisower, B.; Bowman, H.; Flexser, S.; Carmichael, I.

    1978-04-01

    Geologic and geochemical criteria were developed for the occurrence of economic uranium deposits in alkaline igneous rocks. A literature search, a limited chemical analytical program, and visits to three prominent alkaline-rock localities (Ilimaussaq, Greenland; Pocos de Caldas, Brazil; and Powderhorn, Colorado) were made to establish criteria to determine if a site had some uranium resource potential. From the literature, four alkaline-intrusive occurrences of differing character were identified as type-localities for uranium mineralization, and the important aspects of these localities were described. These characteristics were used to categorize and evaluate U.S. occurrences. The literature search disclosed 69 U.S. sites, encompassing nepheline syenite, alkaline granite, and carbonatite. It was possible to compare two-thirds of these sites to the type localities. A ranking system identified ten of the sites as most likely to have uranium resource potential.

  13. Interaction of Pseudomonas putida ATCC 12633 and Bacteriophage gh-1 in Berea Sandstone Rock.

    Science.gov (United States)

    Chang, P L; Yen, T F

    1985-12-01

    Measurements of the passage of Pseudomonas putida ATCC 12633 and a phage-resistant mutant through Berea sandstone rock were made. When bacteriophage gh-1 was adsorbed within the rock matrix, a reduction in the passage of the susceptible but not the resistant cells through the rock was observed.

  14. Limados : Rock peruano

    OpenAIRE

    García Morete, Ramiro

    2013-01-01

    Incentivado por la corriente nuevaolera que llegaba de México, fue señalado por especialistas como pionero del punk. Aunque el plan, era tocar con lo que hubiera. Un recodo ínfimo de un período breve pero sorprendentemente poderoso, los 60 en un país que hizo del rock una expresión propia de su cultura.

  15. Deformations of fractured rock

    International Nuclear Information System (INIS)

    Results of the DBM and FEM analysis in this study indicate that a suitable rock mass for repository of radioactive waste should be moderately jointed (about 1 joint/m2) and surrounded by shear zones of the first order. This allowes for a gentle and flexible deformation under tectonic stresses and prevent the development of large cross-cutting failures in the repository area. (author)

  16. Rock pushing and sampling under rocks on Mars

    Science.gov (United States)

    Moore, H.J.; Liebes, S.; Crouch, D.S.; Clark, L.V.

    1978-01-01

    Viking Lander 2 acquired samples on Mars from beneath two rocks, where living organisms and organic molecules would be protected from ultraviolet radiation. Selection of rocks to be moved was based on scientific and engineering considerations, including rock size, rock shape, burial depth, and location in a sample field. Rock locations and topography were established using the computerized interactive video-stereophotogrammetric system and plotted on vertical profiles and in plan view. Sampler commands were developed and tested on Earth using a full-size lander and surface mock-up. The use of power by the sampler motor correlates with rock movements, which were by plowing, skidding, and rolling. Provenance of the samples was determined by measurements and interpretation of pictures and positions of the sampler arm. Analytical results demonstrate that the samples were, in fact, from beneath the rocks. Results from the Gas Chromatograph-Mass Spectrometer of the Molecular Analysis experiment and the Gas Exchange instrument of the Biology experiment indicate that more adsorbed(?) water occurs in samples under rocks than in samples exposed to the sun. This is consistent with terrestrial arid environments, where more moisture occurs in near-surface soil un- der rocks than in surrounding soil because the net heat flow is toward the soil beneath the rock and the rock cap inhibits evaporation. Inorganic analyses show that samples of soil from under the rocks have significantly less iron than soil exposed to the sun. The scientific significance of analyses of samples under the rocks is only partly evaluated, but some facts are clear. Detectable quantities of martian organic molecules were not found in the sample from under a rock by the Molecular Analysis experiment. The Biology experiments did not find definitive evidence for Earth-like living organisms in their sample. Significant amounts of adsorbed water may be present in the martian regolith. The response of the soil

  17. Rock in Rio: forever young

    Directory of Open Access Journals (Sweden)

    Ricardo Ferreira Freitas

    2014-12-01

    Full Text Available The purpose of this article is to discuss the role of Rock in Rio: The Musical, as herald of megafestival Rock in Rio. Driven by the success that musicals have reached in Brazil, we believe that the design of this spectacle of music, dance and staging renews the brand of the rock festival, once it adds the force of young and healthy bodies to its concept. Moreover, the musical provides Rock in Rio with some distance from the controversal trilogy of sex, drugs and rock and roll, a strong mark of past festivals around the world. Thus, the musical expands the possibilities of growth for the brand.

  18. Targeted Disruption of ROCK1 Causes Insulin Resistance in Vivo*S⃞

    OpenAIRE

    Lee, Dae Ho; Shi, Jianjian; Jeoung, Nam Ho; Kim, Min Seon; Zabolotny, Janice M.; Lee, Sam W.; White, Morris F.; Wei, Lei; Kim, Young-Bum

    2009-01-01

    Insulin signaling is essential for normal glucose homeostasis. Rho-kinase (ROCK) isoforms have been shown to participate in insulin signaling and glucose metabolism in cultured cell lines. To investigate the physiological role of ROCK1 in the regulation of whole body glucose homeostasis and insulin sensitivity in vivo, we studied mice with global disruption of ROCK1. Here we show that, at 16–18 weeks of age, ROCK1-deficient mice exhibited insulin resistance, as reveale...

  19. Rock bolts - Improved design and possibilities

    OpenAIRE

    Thomas-Lepine, Capucine

    2012-01-01

    SummaryRock Bolts, improved design and possibilitiesMaster thesis NTNU 2012Student : Capucine Thomas-LepineSupervisor : Leif LiaKey words : rock foundation, small concrete dam, rock mass classification, rock joints, shear strength of rock discontinuities, fully grouted passive rock bolts designMasters Thesis : “Rock bolts, improved design and possibilities” is a continuation from the Masters Thesis NTNU 2011 “Rock bolts in dams, expected capacity” by Lars Kristian Neby. In...

  20. Musical Structure as Narrative in Rock

    Directory of Open Access Journals (Sweden)

    John Fernando Encarnacao

    2011-09-01

    Full Text Available In an attempt to take a fresh look at the analysis of form in rock music, this paper uses Susan McClary’s (2000 idea of ‘quest narrative’ in Western art music as a starting point. While much pop and rock adheres to the basic structure of the establishment of a home territory, episodes or adventures away, and then a return, my study suggests three categories of rock music form that provide alternatives to common combinations of verses, choruses and bridges through which the quest narrative is delivered. Labyrinth forms present more than the usual number of sections to confound our sense of ‘home’, and consequently of ‘quest’. Single-cell forms use repetition to suggest either a kind of stasis or to disrupt our expectations of beginning, middle and end. Immersive forms blur sectional divisions and invite more sensual and participatory responses to the recorded text. With regard to all of these alternative approaches to structure, Judy Lochhead’s (1992 concept of ‘forming’ is called upon to underline rock music forms that unfold as process, rather than map received formal constructs. Central to the argument are a couple of crucial definitions. Following Theodore Gracyk (1996, it is not songs, as such, but particular recordings that constitute rock music texts. Additionally, narrative is understood not in (direct relation to the lyrics of a song, nor in terms of artists’ biographies or the trajectories of musical styles, but considered in terms of musical structure. It is hoped that this outline of non-narrative musical structures in rock may have applications not only to other types of music, but to other time-based art forms.

  1. Biomarkers and Microbial Fossils In Antarctic Rocks

    Science.gov (United States)

    Wierzchos, J.; Ascaso, C.

    Lithobiontic microbial communities living within Antarctic rocks are an example of survival in an extremely cold and dry environment. Any unfavourable change in ex- ternal conditions can result in the death and disappearance of microscopic organisms, and this may be followed by the appearance of trace biomarkers and microbial fossils. The extinction of these microorganisms in some zones of the Ross Desert, probably provoked by the hostile environment, might be considered a good terrestrial analogue of the first stage of the disappearance of possible life on early Mars. Granite samples from maritime Antarctica (Granite Harbour) and sandstone rocks from the continental Ross Desert were collected with the aim of searching for biomarkers and microbial fossils at the microscopic level of observation. To this end, a novel in situ applica- tion of scanning electron microscopy with backscattered electron imaging was com- bined with the simultaneous use of X-ray energy dispersive spectroscopy techniques. Our findings confirm the existence of inorganic biomarkers in the form of physico- chemically bioweathered minerals within the granitic rocks. The presence of Fe-rich diagenetic minerals, such as iron hydroxide nanocrystals and biogenic clays around chasmoendolithic hyphae and bacterial cells was also observed. Others biomarkers, including inorganic deposits such as calcium oxalates and silica accumulations, are clear signs of endolithic microorganism activity. The interior of the sandstone rocks (Ross Desert, Mt. Fleming) reveal the presence of microbial fossils of algae and other endolithic microorganisms. These microbial fossils, detected for the first time within Antarctic rocks, contain well preserved and morphologically distinguishable relics of ultrastructural cytoplasm elements, such as cell walls, chloroplast membranes, and oc- casionally, pyrenoids and traces of organic matter. These structures are similar to those observed in live cells also found in Antarctic

  2. ROCK1 as a novel prognostic marker in vulvar cancer

    DEFF Research Database (Denmark)

    Akagi, Erica M; Lavorato-Rocha, André M; Maia, Beatriz de Melo;

    2014-01-01

    infection, but most cases develop in women aged over 50 years through poorly understood genetic mechanisms. Rho-associated coiled-coil-containing protein kinase 1 (ROCK1) has been implicated in many cellular processes, but its function in vulvar cancer has never been examined. In this study, we aimed...... to determine the prognostic value of ROCK1 gene and protein analysis in vulvar squamous cell carcinoma (VSCC). METHODS: ROCK1 expression levels were measured in 16 vulvar tumour samples and adjacent normal tissue by qRT-PCR. Further, 96 VSCC samples were examined by immunohistochemistry (IHC) to confirm...... tissue compared with the tumour samples (p = 0.016). By IHC, 100% of invasive front areas of the tumour and 95.8% of central tumour areas were positive for ROCK1. Greater expression of ROCK1 was associated with the absence of lymph node metastasis (p = 0.022) and a lower depth of invasion (p = 0...

  3. Rock mechanics for hard rock nuclear waste repositories

    International Nuclear Information System (INIS)

    The mined geologic burial of high level nuclear waste is now the favored option for disposal. The US National Waste Terminal Storage Program designed to achieve this disposal includes an extensive rock mechanics component related to the design of the wastes repositories. The plan currently considers five candidate rock types. This paper deals with the three hard rocks among them: basalt, granite, and tuff. Their behavior is governed by geological discontinuities. Salt and shale, which exhibit behavior closer to that of a continuum, are not considered here. This paper discusses both the generic rock mechanics R and D, which are required for repository design, as well as examples of projects related to hard rock waste storage. The examples include programs in basalt (Hanford/Washington), in granitic rocks (Climax/Nevada Test Site, Idaho Springs/Colorado, Pinawa/Canada, Oracle/Arizona, and Stripa/Sweden), and in tuff

  4. Sealing of fractured rock

    International Nuclear Information System (INIS)

    This paper consists of a presentation of the third phase of the Stripa Project. This phase was dedicated to fracture sealing. First of all it has been necessary to show that fine-grained grouts could effectively be injected in relatively fine cracks, and that the fluidity of bentonite could also be enhanced. The field tests comprised investigation of excavation-induced disturbance and attempts to seal disturbed rock, and, in separate tests, grouting of deposition holes and a natural fine-fracture zone. (TEC). 12 figs., 1 tab., 6 refs

  5. From stones to rocks

    Science.gov (United States)

    Mortier, Marie-Astrid; Jean-Leroux, Kathleen; Cirio, Raymond

    2013-04-01

    With the Aquila earthquake in 2009, earthquake prediction is more and more necessary nowadays, and people are waiting for even more accurate data. Earthquake accuracy has increased in recent times mainly thanks to the understanding of how oceanic expansion works and significant development of numerical seismic prediction models. Despite the improvements, the location and the magnitude can't be as accurate as citizen and authorities would like. The basis of anticipating earthquakes requires the understanding of: - The composition of the earth, - The structure of the earth, - The relations and movements between the different parts of the surface of the earth. In order to answer these questions, the Alps are an interesting field for students. This study combines natural curiosity about understanding the predictable part of natural hazard in geology and scientific skills on site: observing and drawing landscape, choosing and reading a representative core drilling, replacing the facts chronologically and considering the age, the length of time and the strength needed. This experience requires students to have an approach of time and space radically different than the one they can consider in a classroom. It also limits their imagination, in a positive way, because they realize that prediction is based on real data and some of former theories have become present paradigms thanks to geologists. On each location the analyzed data include landscape, core drilling and the relation established between them by students. The data is used by the students to understand the meaning, so that the history of the formation of the rocks tells by the rocks can be explained. Until this year, the CBGA's perspective regarding the study of the Alps ground allowed students to build the story of the creation and disappearance of the ocean, which was a concept required by French educational authorities. But not long ago, the authorities changed their scientific expectations. To meet the

  6. Rock mechanics data package

    International Nuclear Information System (INIS)

    This data package provides a summary of available laboratory and in situ stress field test results from site characterization investigations by the Basalt Waste Isolation Project Modeling and Analysis Group. The objective is to furnish rock mechanics information for use by Rockwell Hanford Operations and their subcontractors in performance assessment and engineering studies. This release includes Reference Repository Location (RRL) site specific laboratory and field test data from boreholes RRL-2, RRL-6, and RRL-14 as well as previous Hanford wide data available as of April, 1985. 25 refs., 9 figs., 16 tabs

  7. Enhanced osteogenesis of human alveolar bone-derived mesenchymal stem cells for tooth tissue engineering using fluid shear stress in a rocking culture method.

    Science.gov (United States)

    Lim, Ki-Taek; Kim, Jangho; Seonwoo, Hoon; Chang, Jung Uk; Choi, Hwajung; Hexiu, Jin; Cho, Woo Jae; Choung, Pill-Hoon; Chung, Jong Hoon

    2013-02-01

    This study instituted a simple approach to stimulate alveolar bone regeneration for tooth tissue engineering by controlling effects of low fluid dynamic shear stress (LFDSS) on growth and differentiation in vitro. Human alveolar bone-derived mesenchymal stem cells (hABMSCs) harvested from human mandibular alveolar bone were cultured with LFDSS to generate cultures containing bone-like formations. To distinguish between osteodifferentiation and bone-like formation, cells were cultured either with or without fluid shear stress. The calcium content and alkaline phosphatase (ALP) activity of hABMSCs were used as indicators of osteogenesis. Cell viability and proliferation after stimulating with LFDSS for 10-60 min/day were higher than with longer stimulations. Mineralized nodules formed when osteoblasts were cultured with an induction medium, a marker of osteogenic differentiation. ALP activity tended to increase after 10 and 60 min/day of stimulation. In addition, LFDSS conditions also increased gene expression of IBSP, RUNX2, COL-I, ALP, OCN, and OPN, as shown by reverse transcriptase-polymerase chain reaction. From the results of a proteomics array, LFDSS groups were intensely expressed with several factors (EGF, HGF, IGF, TGF, and PDGF). Furthermore, CD146 and Stro-1 expression increased in cells treated with 30 min/day and decreased in cells treated with 120 min/day, as determined by cell surface antigen analysis by fluorescence-activated cell-sorting analysis. These results strongly showed that LFDSS at the proper intensity and time enhanced the differentiation and maturation of hABMSCs. In conclusion, an appropriate level of LFDSS can potently and positively modulate proliferation and differentiation in hABMSCs.

  8. Fossils, rocks, and time

    Science.gov (United States)

    Edwards, Lucy E.; Pojeta, John

    1999-01-01

    We study our Earth for many reasons: to find water to drink or oil to run our cars or coal to heat our homes, to know where to expect earthquakes or landslides or floods, and to try to understand our natural surroundings. Earth is constantly changing--nothing on its surface is truly permanent. Rocks that are now on top of a mountain may once have been at the bottom of the sea. Thus, to understand the world we live on, we must add the dimension of time. We must study Earth's history. When we talk about recorded history, time is measured in years, centuries, and tens of centuries. When we talk about Earth history, time is measured in millions and billions of years. Time is an everyday part of our lives. We keep track of time with a marvelous invention, the calendar, which is based on the movements of Earth in space. One spin of Earth on its axis is a day, and one trip around the Sun is a year. The modern calendar is a great achievement, developed over many thousands of years as theory and technology improved. People who study Earth's history also use a type of calendar, called the geologic time scale. It looks very different from the familiar calendar. In some ways, it is more like a book, and the rocks are its pages. Some of the pages are torn or missing, and the pages are not numbered, but geology gives us the tools to help us read this book.

  9. Rock Properties Model

    International Nuclear Information System (INIS)

    The purpose of this model report is to document the Rock Properties Model version 3.1 with regard to input data, model methods, assumptions, uncertainties and limitations of model results, and qualification status of the model. The report also documents the differences between the current and previous versions and validation of the model. The rock properties model provides mean matrix and lithophysae porosity, and the cross-correlated mean bulk density as direct input to the ''Saturated Zone Flow and Transport Model Abstraction'', MDL-NBS-HS-000021, REV 02 (BSC 2004 [DIRS 170042]). The constraints, caveats, and limitations associated with this model are discussed in Section 6.6 and 8.2. Model validation accomplished by corroboration with data not cited as direct input is discussed in Section 7. The revision of this model report was performed as part of activities being conducted under the ''Technical Work Plan for: The Integrated Site Model, Revision 05'' (BSC 2004 [DIRS 169635]). The purpose of this revision is to bring the report up to current procedural requirements and address the Regulatory Integration Team evaluation comments. The work plan describes the scope, objectives, tasks, methodology, and procedures for this process

  10. A smart rock

    Science.gov (United States)

    Pressel, Phil

    2014-12-01

    This project was to design and build a protective weapon for a group of associations that believed in aliens and UFO's. They collected enough contributions from societies and individuals to be able to sponsor and totally fund the design, fabrication and testing of this equipment. The location of this facility is classified. It also eventually was redesigned by the Quartus Engineering Company for use at a major amusement park as a "shoot at targets facility." The challenge of this project was to design a "smart rock," namely an infrared bullet (the size of a gallon can of paint) that could be shot from the ground to intercept a UFO or any incoming suspicious item heading towards the earth. Some of the challenges to design this weapon were to feed cryogenic helium at 5 degrees Kelvin from an inair environment through a unique rotary coupling and air-vacuum seal while spinning the bullet at 1500 rpm and maintain its dynamic stability (wobble) about its spin axis to less than 10 micro-radians (2 arc seconds) while it operated in a vacuum. Precision optics monitored the dynamic motion of the "smart rock."

  11. Rock Properties Model

    Energy Technology Data Exchange (ETDEWEB)

    C. Lum

    2004-09-16

    The purpose of this model report is to document the Rock Properties Model version 3.1 with regard to input data, model methods, assumptions, uncertainties and limitations of model results, and qualification status of the model. The report also documents the differences between the current and previous versions and validation of the model. The rock properties model provides mean matrix and lithophysae porosity, and the cross-correlated mean bulk density as direct input to the ''Saturated Zone Flow and Transport Model Abstraction'', MDL-NBS-HS-000021, REV 02 (BSC 2004 [DIRS 170042]). The constraints, caveats, and limitations associated with this model are discussed in Section 6.6 and 8.2. Model validation accomplished by corroboration with data not cited as direct input is discussed in Section 7. The revision of this model report was performed as part of activities being conducted under the ''Technical Work Plan for: The Integrated Site Model, Revision 05'' (BSC 2004 [DIRS 169635]). The purpose of this revision is to bring the report up to current procedural requirements and address the Regulatory Integration Team evaluation comments. The work plan describes the scope, objectives, tasks, methodology, and procedures for this process.

  12. Rock critics as 'Mouldy Modernists'

    Directory of Open Access Journals (Sweden)

    Becky Shepherd

    2011-09-01

    Full Text Available Contemporary rock criticism appears to be firmly tied to the past. The specialist music press valorise rock music of the 1960s and 1970s, and new emerging artists are championed for their ‘retro’ sounding music by journalists who compare the sound of these new artists with those included in the established ‘canon’ of rock music. This article examines the narrative tropes of authenticity and nostalgia that frame the retrospective focus of this contemporary rock writing, and most significantly, the maintenance of the rock canon within contemporary popular culture. The article concludes by suggesting that while contemporary rock criticism is predominately characterised by nostalgia, this nostalgia is not simply a passive romanticism of the past. Rather, this nostalgia fuels a process of active recontextualisation within contemporary popular culture.

  13. Surface slick trajectories and risk analysis to oil spill and its derivates, caused by vessel in the Vitoria Bay and Espirito Santo Bay; Analise da trajetoria e dos riscos do derrame de petroleo e seus derivados proveniente da area de fundeio dos portos situados nas baias de Vitoria e do Espirito Santo

    Energy Technology Data Exchange (ETDEWEB)

    Fontana, A.R. [Espirito Santo Univ., Vitoria, ES (Brazil). Programa de Pos-graduacao em Engenharia Ambiental]. E-mail: arfont@terra.com.br; Sarmento, R. [Espirito Santo Univ., Vitoria, ES (Brazil)]. E-mail: robsar@npd.ufes.br

    2003-07-01

    This report presents information of surface slick trajectories and risk analysis to oil spill, provoked by vessel in the Vitoria Bay and Espirito Santo Bay anchorage port area. The trajectory has been simulated by mathematical modeling surface spill trajectory, pushed by wind and tidal currents. Those information are a contribution to elaborate contingency plans to the ports activities in this region. (author)

  14. [Hearing disorders and rock music].

    Science.gov (United States)

    Lindhardt, Bjarne Orskov

    2008-12-15

    Only few studies have investigated the frequency of hearing disorders in rock musicians. Performing rock music is apparently associated with a hearing loss in a fraction of musicians. Tinnitus and hyperacusis are more common among rock musicians than among the background population. It seems as if some sort of resistance against further hearing loss is developed over time. The use of ear protection devices have not been studied systematically but appears to be associated with diminished hearing loss. PMID:19128557

  15. Electromagnetic emissions during rock blasting

    Science.gov (United States)

    O'Keefe, S. G.; Thiel, D. V.

    1991-05-01

    Radio emissions during quarry blasting have been recorded in the audio frequency band. Three distinct mechanisms are suggested to explain the observed results; rock fracture at the time of the explosion, charged rocks discharging on impact with the pit floor and micro-fracture of the remaining rock wall due to pressure adjustment of the bench behind the blast. The last mechanism was evident by a train of discrete impulses recorded for up to one minute after the blast. It is assumed that during this time the rock behind the blast was subjected to a significant change in pressure. This may be related to ELF observations during earthquakes.

  16. Cigarette smoke extract-induced p120-mediated NF-κB activation in human epithelial cells is dependent on the RhoA/ROCK pathway

    Science.gov (United States)

    Zhang, Chao; Qin, Shenghui; Qin, Lingzhi; Liu, Liwei; Sun, Wenjia; Li, Xiyu; Li, Naping; Wu, Renliang; Wang, Xi

    2016-09-01

    Cigarette smoke exposure is a major cause of chronic obstructive pulmonary disease (COPD), but the underlying molecular inflammatory mechanisms remain poorly understood. Previous studies have found that smoke disrupts cell-cell adhesion by inducing epithelial barrier damage to the adherens junction proteins, primarily E-cadherin (E-cad) and p120-catenin (p120). Recently, the anti-inflammatory role of p120 has drawn increasing attention. In this study, we demonstrate that p120 has a role in the cigarette smoke extract-induced inflammatory response, presumably by regulating NF-κB signaling activation. Mechanistically, we show that p120-mediated NF-κB signaling activation in airway epithelial inflammation is partially RhoA dependent and is independent of E-cad. These results provide novel evidence for the role of p120 in the anti-inflammatory response.

  17. Cigarette smoke extract-induced p120-mediated NF-κB activation in human epithelial cells is dependent on the RhoA/ROCK pathway

    Science.gov (United States)

    Zhang, Chao; Qin, Shenghui; Qin, Lingzhi; Liu, Liwei; Sun, Wenjia; Li, Xiyu; Li, Naping; Wu, Renliang; Wang, Xi

    2016-01-01

    Cigarette smoke exposure is a major cause of chronic obstructive pulmonary disease (COPD), but the underlying molecular inflammatory mechanisms remain poorly understood. Previous studies have found that smoke disrupts cell-cell adhesion by inducing epithelial barrier damage to the adherens junction proteins, primarily E-cadherin (E-cad) and p120-catenin (p120). Recently, the anti-inflammatory role of p120 has drawn increasing attention. In this study, we demonstrate that p120 has a role in the cigarette smoke extract-induced inflammatory response, presumably by regulating NF-κB signaling activation. Mechanistically, we show that p120-mediated NF-κB signaling activation in airway epithelial inflammation is partially RhoA dependent and is independent of E-cad. These results provide novel evidence for the role of p120 in the anti-inflammatory response. PMID:27586697

  18. Cigarette smoke extract-induced p120-mediated NF-κB activation in human epithelial cells is dependent on the RhoA/ROCK pathway.

    Science.gov (United States)

    Zhang, Chao; Qin, Shenghui; Qin, Lingzhi; Liu, Liwei; Sun, Wenjia; Li, Xiyu; Li, Naping; Wu, Renliang; Wang, Xi

    2016-01-01

    Cigarette smoke exposure is a major cause of chronic obstructive pulmonary disease (COPD), but the underlying molecular inflammatory mechanisms remain poorly understood. Previous studies have found that smoke disrupts cell-cell adhesion by inducing epithelial barrier damage to the adherens junction proteins, primarily E-cadherin (E-cad) and p120-catenin (p120). Recently, the anti-inflammatory role of p120 has drawn increasing attention. In this study, we demonstrate that p120 has a role in the cigarette smoke extract-induced inflammatory response, presumably by regulating NF-κB signaling activation. Mechanistically, we show that p120-mediated NF-κB signaling activation in airway epithelial inflammation is partially RhoA dependent and is independent of E-cad. These results provide novel evidence for the role of p120 in the anti-inflammatory response. PMID:27586697

  19. Rock.XML - Towards a library of rock physics models

    Science.gov (United States)

    Jensen, Erling Hugo; Hauge, Ragnar; Ulvmoen, Marit; Johansen, Tor Arne; Drottning, Åsmund

    2016-08-01

    Rock physics modelling provides tools for correlating physical properties of rocks and their constituents to the geophysical observations we measure on a larger scale. Many different theoretical and empirical models exist, to cover the range of different types of rocks. However, upon reviewing these, we see that they are all built around a few main concepts. Based on this observation, we propose a format for digitally storing the specifications for rock physics models which we have named Rock.XML. It does not only contain data about the various constituents, but also the theories and how they are used to combine these building blocks to make a representative model for a particular rock. The format is based on the Extensible Markup Language XML, making it flexible enough to handle complex models as well as scalable towards extending it with new theories and models. This technology has great advantages as far as documenting and exchanging models in an unambiguous way between people and between software. Rock.XML can become a platform for creating a library of rock physics models; making them more accessible to everyone.

  20. Design, synthesis, and biological evaluation of novel, highly active soft ROCK inhibitors.

    Science.gov (United States)

    Boland, Sandro; Bourin, Arnaud; Alen, Jo; Geraets, Jacques; Schroeders, Pieter; Castermans, Karolien; Kindt, Nele; Boumans, Nicki; Panitti, Laura; Fransen, Silke; Vanormelingen, Jessica; Stassen, Jean Marie; Leysen, Dirk; Defert, Olivier

    2015-05-28

    ROCK1 and ROCK2 play important roles in numerous cellular functions, including smooth muscle cell contraction, cell proliferation, adhesion, and migration. Consequently, ROCK inhibitors are of interest for treating multiple indications including cardiovascular diseases, inflammatory and autoimmune diseases, lung diseases, and eye diseases. However, systemic inhibition of ROCK is expected to result in significant side effects. Strategies allowing reduced systemic exposure are therefore of interest. In a continuing effort toward identification of ROCK inhibitors, we here report the design, synthesis, and evaluation of novel soft ROCK inhibitors displaying an ester function allowing their rapid inactivation in the systemic circulation. Those compounds display subnanomolar activity against ROCK and strong differences of functional activity between parent compounds and expected metabolites. The binding mode of a representative compound was determined experimentally in a single-crystal X-ray diffraction study. Enzymes responsible for inactivation of these compounds once they enter systemic circulation are also discussed.

  1. Bacterial Life and Dinitrogen Fixation at a Gypsum Rock

    OpenAIRE

    Boison, Gudrun; Mergel, Alexander; Jolkver, Helena; Bothe, Hermann

    2004-01-01

    The organisms of a bluish-green layer beneath the shards of a gypsum rock were characterized by molecular techniques. The cyanobacterial consortium consisted almost exclusively of Chroococcidiopsis spp. The organisms of the shards expressed nitrogenase activity (C2H2 reduction) aerobically and in light. After a prolonged period of drought at the rock, the cells were inactive, but they resumed nitrogenase activity 2 to 3 days after the addition of water. In a suspension culture of Chroococcidi...

  2. Rock the Globe

    CERN Multimedia

    Laëtitia Pedroso

    2010-01-01

    Created in 2005, the Swiss rock band "Wind of Change" is now candidate for the Eurovision Song Contest 2011 with a new song " Night & Light " with the music video filmed at CERN.   With over 20 gigs under their belt and two albums already released, the five members of the band (Alex Büchi, vocals; Arthur Spierer, drums; David Gantner, bass; Romain Mage and Yannick Gaudy, guitar) continue to excite audiences. For their latest composition "Night & Light", the group filmed their music video in the Globe of Science and Innovation. Winning the Eurovision contest would be a springboard in their artistic career for these young musicians. The selection results will be available December 11, 2010.      

  3. Rock and soil rheology

    International Nuclear Information System (INIS)

    The aim of the Euromech Colloquium 196 devoted to Rock and Soil Rheology is to review some of the main results obtained in the last years in this field of research and also to formulate some of the major not yet solved problems which are now under consideration. Exchange of opinions and scientific discussions are quite helpful mainly in those areas where some approaches are controversial and the progress made is quite fast. That is especially true for the rheology of geomaterials, domain of great interest for mining and petroleum engineers, engineering geology, seismology, geophysics, civil engineering, nuclear and industrial waste storage, geothermal energy storage, caverns for sports, culture, telecommunications, storage of goods and foodstuffs (cold, hot and refrigerated storages), underground oil and natural gas reservoirs etc. Some of the last obtained results are mentioned in the present volume. (orig./HP)

  4. Geoelectrical Classification of Gypsum Rocks

    Science.gov (United States)

    Guinea, Ander; Playà, Elisabet; Rivero, Lluís; Himi, Mahjoub; Bosch, Ricard

    2010-12-01

    Gypsum rocks are widely exploited in the world as industrial minerals. The purity of the gypsum rocks (percentage in gypsum mineral in the whole rock) is a critical factor to evaluate the potential exploitability of a gypsum deposit. It is considered than purities higher than 80% in gypsum are required to be economically profitable. Gypsum deposits have been studied with geoelectrical methods; a direct relationship between the electrical resistivity values of the gypsum rocks and its lithological composition has been established, with the presence of lutites being the main controlling factor in the geoelectrical response of the deposit. This phenomenon has been quantified in the present study, by means of a combination of theoretical calculations, laboratory measurements and field data acquisition. Direct modelling has been performed; the data have been inverted to obtain the mean electrical resistivity of the models. The laboratory measurements have been obtained from artificial gypsum-clay mixture pills, and the electrical resistivity has been measured using a simple electrical circuit with direct current power supply. Finally, electrical resistivity tomography data have been acquired in different evaporite Tertiary basins located in North East Spain; the selected gypsum deposits have different gypsum compositions. The geoelectrical response of gypsum rocks has been determined by comparing the resistivity values obtained from theoretical models, laboratory tests and field examples. A geoelectrical classification of gypsum rocks defining three types of gypsum rocks has been elaborated: (a) Pure Gypsum Rocks (>75% of gypsum content), (b) Transitional Gypsum Rocks (75-55%), and (c) Lutites and Gypsum-rich Lutites (800 ohm.m, can be exploited as industrial rocks. The methodology used could be applied in other geoelectrical rock studies, given that this relationship between the resistive particles embedded within a conductive matrix depends on the connectivity of the

  5. Motion analysis of waste rock in gas-solids fluidized bed in coal dry beneficiation

    Institute of Scientific and Technical Information of China (English)

    郭迎福; 陈安华; 张永忠; 邓志鹏; 毛树楷

    2002-01-01

    Through the analysis of forces acting on the waste rock in the gas-solid fluidized bed, the waste rock velocity equations and displacement equations in the gas-solids fluidized bed were achieved and the influential factors of the waste rock motion in the fluidized bed were studied in this paper. The conclusions show that the primary factors influencing the waste rock motion are the waste rock grain size and the scraper velocity according to the computer simulation. This has provided the theoretical foundation both for improving the separating effect and ascertaining the length of the separating cell.

  6. Rock Segmentation through Edge Regrouping

    Science.gov (United States)

    Burl, Michael

    2008-01-01

    Rockster is an algorithm that automatically identifies the locations and boundaries of rocks imaged by the rover hazard cameras (hazcams), navigation cameras (navcams), or panoramic cameras (pancams). The software uses edge detection and edge regrouping to identify closed contours that separate the rocks from the background.

  7. Rock Art in Kurdistan Iran

    Directory of Open Access Journals (Sweden)

    Jamal Lahafian

    2013-12-01

    Full Text Available Kurdistan, with great potential and prehistoric resources, has numerous petroglyphs in different areas of the province. During the last 14 years of extensive field study, more than 30 sites of rock art have been identified and introduced by the author. In this article, we summarize these rock art areas in Iranian Kurdistan.

  8. Rock Art in Kurdistan Iran

    OpenAIRE

    Jamal Lahafian

    2013-01-01

    Kurdistan, with great potential and prehistoric resources, has numerous petroglyphs in different areas of the province. During the last 14 years of extensive field study, more than 30 sites of rock art have been identified and introduced by the author. In this article, we summarize these rock art areas in Iranian Kurdistan.

  9. Workshop on hydrology of crystalline basement rocks

    Energy Technology Data Exchange (ETDEWEB)

    Davis, S.N. (comp.)

    1981-08-01

    This workshop covered the following subjects: measurements in relatively shallow boreholes; measurement and interpretation of data from deep boreholes; hydrologic properties of crystalline rocks as interpreted by geophysics and field geology; rock mechanics related to hydrology of crystalline rocks; the possible contributions of modeling to the understanding of the hydrology of crystalline rocks; and geochemical interpretations of the hydrology of crystalline rocks. (MHR)

  10. Rock suitability classification RSC 2012

    Energy Technology Data Exchange (ETDEWEB)

    McEwen, T. (ed.) [McEwen Consulting, Leicester (United Kingdom); Kapyaho, A. [Geological Survey of Finland, Espoo (Finland); Hella, P. [Saanio and Riekkola, Helsinki (Finland); Aro, S.; Kosunen, P.; Mattila, J.; Pere, T.

    2012-12-15

    This report presents Posiva's Rock Suitability Classification (RSC) system, developed for locating suitable rock volumes for repository design and construction. The RSC system comprises both the revised rock suitability criteria and the procedure for the suitability classification during the construction of the repository. The aim of the classification is to avoid such features of the host rock that may be detrimental to the favourable conditions within the repository, either initially or in the long term. This report also discusses the implications of applying the RSC system for the fulfilment of the regulatory requirements concerning the host rock as a natural barrier and the site's overall suitability for hosting a final repository of spent nuclear fuel.

  11. Rock suitability classification RSC 2012

    International Nuclear Information System (INIS)

    This report presents Posiva's Rock Suitability Classification (RSC) system, developed for locating suitable rock volumes for repository design and construction. The RSC system comprises both the revised rock suitability criteria and the procedure for the suitability classification during the construction of the repository. The aim of the classification is to avoid such features of the host rock that may be detrimental to the favourable conditions within the repository, either initially or in the long term. This report also discusses the implications of applying the RSC system for the fulfilment of the regulatory requirements concerning the host rock as a natural barrier and the site's overall suitability for hosting a final repository of spent nuclear fuel

  12. Seismic properties of polyphase rocks

    Science.gov (United States)

    Wang, Qin

    2005-11-01

    Knowledge about the seismic properties of polyphase rocks is fundamental for interpreting seismic refraction and reflection data and for establishing lithospheric structure and composition models. This study aims to obtain more precise relationships between seismic properties of rocks and controlling factors (e.g., pressure, temperature, mineralogical and chemical compositions, microstructure of rocks), particularly for those rocks imprinted by ultrahigh-pressure (UHP) metamorphism. These relationships will be very helpful to extrapolate calculated and measured seismic properties of rocks to depths of interest and to engender interpretations relevant to petrological composition and tectonic process. An Internet Database of Rock Seismic Properties (DRSP) was set up and a Handbook of Seismic Properties of Minerals, Rocks and Ores was published. They comprise almost all data available in the literature during the past 4 decades and can serve as a convenient, comprehensive and concise information source on physical properties of rocks to the earth sciences and geotechnical communities. Statistical results of the DRSP reveal the dependence of seismic properties on density, porosity, humidity, and mineralogical and chemical compositions. Using 16 different averaging methods, we calculated P-wave velocities of 696 dry samples according to the volume fraction and elastic constants of each constituent mineral. Although only 22 common minerals were taken into account in the computation, the calculated P-wave velocities agree well with laboratory values measured at about 300 MPa, where most microcracks are closed and the mean Vp of a polymineralic rock is exclusively controlled by its modal composition. However, none of these mixture rules can simultaneously fit measured P-wave velocities for all lithologies or at all pressures. Therefore, more prudence is required in selecting an appropriate mixture rule for calculation of seismic velocities of different rock types.

  13. Remedial Action Plan and Site Design for Stabilization of the Inactive Uranium Mill Tailings Sites at Slick Rock, Colorado: Appendix B to Attachment 3, Lithologic logs and monitor well construction information. Final report

    International Nuclear Information System (INIS)

    This volume contains lithology logs and monitor well construction information for: NC processing site; UC processing site; and Burro Canyon disposal site. This information pertains to the ground water hydrology investigations which is attachment 3 of this series of reports

  14. Research on Mechanism of Rock Burst Generation and Development for High Stress Rock Tunnels

    Institute of Scientific and Technical Information of China (English)

    高全臣; 赫建明; 王代华

    2001-01-01

    Through the investigation and analysis of high stress distribution in surrounding rock during the excavation of rock tunnels,the key factors to cause rock burst and the mechanism of rock burst generation and development are researched. The result shows that the scale and range of rock burst are related with elastic deformation energy storied in rock mass and the characteristics of unloading stress waves. The measures of preventing from rock burst for high stress rock tunnels are put forward.

  15. The slick that never was

    Digital Repository Service at National Institute of Oceanography (India)

    SenGupta, R.

    ). The statement follows a review of the available technologies by Consultants in Environ- mental Sciences in which they conclude that most disin- fection methods suffer from either high cost, ques- tionable effectiveness, or environmental drawbacks... more than 5000 sewage works are equipped with dechlorination systems, substantially increasing the treatment costs. Ozone, on the other hand, is a far more effective disinfectant acting as a bactericide and viru- cide at low doses. Unfortuantely...

  16. Remote sensing of oil slicks

    Digital Repository Service at National Institute of Oceanography (India)

    Fondekar, S.P.; Rao, L.V.G.

    , passive microwave radiometer, laser beam fluorosensor and laser-illuminated active gated television. These sensors provide more objective information for detection, quantification and classification of oil as well as identification of a polluting vessel. A...

  17. Out of a Slick Shadow

    Institute of Scientific and Technical Information of China (English)

    WANG JUN

    2010-01-01

    @@ Fang Shaolan,from Huangshan City of central Anhui Province,arrived in northeast China's coastal Dalian City on July 27 for a vacation with seven family members.Before coming to Dalian,Fang heard from media reports that the spilled oil more than a week ago had been almost cleaned up and much of the sea near Dalian hadn't been polluted.

  18. Out of a Slick Shadow

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    Repercussions of an oil spill in China’s coastal Dalian City have yet to be thoroughly measured and eliminated Fang Shaolan, from Huangshan City of central Anhui Province, arrived in northeast China’s coastal Dalian City on July 27 for a vacation with seven family members.Before coming to Dalian,Fang heard from media reports that the spilled oil more than a week ago had been almost cleaned up and much of the sea near Dalian hadn’t been polluted.

  19. Biogenic Cracks in Porous Rock

    Science.gov (United States)

    Hemmerle, A.; Hartung, J.; Hallatschek, O.; Goehring, L.; Herminghaus, S.

    2014-12-01

    Microorganisms growing on and inside porous rock may fracture it by various processes. Some of the mechanisms of biofouling and bioweathering are today identified and partially understood but most emphasis is on chemical weathering, while mechanical contributions have been neglected. However, as demonstrated by the perseverance of a seed germinating and cracking up a concrete block, the turgor pressure of living organisms can be very significant. Here, we present results of a systematic study of the effects of the mechanical forces of growing microbial populations on the weathering of porous media. We designed a model porous medium made of glass beads held together by polydimethylsiloxane (PDMS), a curable polymer. The rheological properties of the porous medium, whose shape and size are tunable, can be controlled by the ratio of crosslinker to base used in the PDMS (see Fig. 1). Glass and PDMS being inert to most chemicals, we are able to focus on the mechanical processes of biodeterioration, excluding any chemical weathering. Inspired by recent measurements of the high pressure (~0.5 Mpa) exerted by a growing population of yeasts trapped in a microfluidic device, we show that yeast cells can be cultured homogeneously within porous medium until saturation of the porous space. We investigate then the effects of such an inner pressure on the mechanical properties of the sample. Using the same model system, we study also the complex interplay between biofilms and porous media. We focus in particular on the effects of pore size on the penetration of the biofilm within the porous sample, and on the resulting deformations of the matrix, opening new perspectives into the understanding of life in complex geometry. Figure 1. Left : cell culture growing in a model porous medium. The white spheres represent the grains, bonds are displayed in grey, and microbes in green. Right: microscopy picture of glass beads linked by PDMS bridges, scale bar: 100 μm.

  20. Rock salt constitutive modeling

    Energy Technology Data Exchange (ETDEWEB)

    Nickell, R.E.

    1980-03-18

    The Serata model is the best operational model available today because it incorporates: (1) a yield function to demarcate between viscoelastic and viscoplastic behavior of rock salt; (2) a pressure and temperature dependence for yield stresses; and (3) a standard linear solid, which can be readily extended into the non-linear regime, to represent creep behavior. Its only deficiencies appear to be the lack of secondary creep behavior (a free dashpot) and some unsettling arbitrariness about the Poisson's ratio (..nu.. ..-->.. 0.5) argument for viscoplasticity. The Sandia/WIPP model will have good primary and secondary creep capability, but lacks the viscoplastic behavior. In some cases, estimated inelastic strains may be underpredicted. If a creep acceleration mechanism associated with brine inclusions is observed, this model may require extensive revision. Most of the other models available (SAI, RE-SPEC, etc.) are only useful for short-term calculations, because they employ temporal power law (t/sup n/) primary creep representations. These models are unsatisfactory because they cannot represent dual mechanisms with differing characteristic times. An approach based upon combined creep and plasticity is recommended in order to remove the remaining deficiency in the Serata model. DOE/Sandia/WIPP should be encouraged to move aggressively in this regard.

  1. They will rock you!

    CERN Multimedia

    Anaïs Schaeffer

    2013-01-01

    On 30 September, CERN will be the venue for one of the most prestigious events of the year: the concert for the Bosons&More event, the Organization’s celebration of the remarkable performance of the LHC and all its technical systems, as well as the recent fundamental discoveries. Topping the bill will be the Orchestre de la Suisse Romande, the CERN Choir, the Zürcher Sing-Akademie and the Alan Parsons Live Project rock group, who have joined forces to create an unforgettable evening’s entertainment.   The Orchestre de la Suisse Romande, directed by Maestro Neeme Järvi, artistic and musical director of the OSR. (Image: Grégory Maillot). >>> From the Orchestre de la Suisse Romande… Henk Swinnen, General Manager of the Orchestre de la Suisse Romande (OSR), answers some questions for the CERN Bulletin, just a few days before the event. How did this project come about? When CERN invited us to take part in the B...

  2. Uranium series, volcanic rocks

    Science.gov (United States)

    Vazquez, Jorge A.

    2014-01-01

    Application of U-series dating to volcanic rocks provides unique and valuable information about the absolute timing of crystallization and differentiation of magmas prior to eruption. The 238U–230Th and 230Th-226Ra methods are the most commonly employed for dating the crystallization of mafic to silicic magmas that erupt at volcanoes. Dates derived from the U–Th and Ra–Th methods reflect crystallization because diffusion of these elements at magmatic temperatures is sluggish (Cherniak 2010) and diffusive re-equilibration is insignificant over the timescales (less than or equal to 10^5 years) typically associated with pre-eruptive storage of nearly all magma compositions (Cooper and Reid 2008). Other dating methods based on elements that diffuse rapidly at magmatic temperatures, such as the 40Ar/39Ar and (U–Th)/He methods, yield dates for the cooling of magma at the time of eruption. Disequilibrium of some short-lived daughters of the uranium series such as 210Po may be fractionated by saturation of a volatile phase and can be employed to date magmatic gas loss that is synchronous with volcanic eruption (e.g., Rubin et al. 1994).

  3. 油粒子体积对扩散的影响及油膜粒子化改进%Impact of Size of Oil-particle on Oil Film and Improved Method of Changing Oil Slick into Particles

    Institute of Scientific and Technical Information of China (English)

    杨红; 王珂; 胡松; 林军; 韩众; 解满俊

    2011-01-01

    In the application of oil-particle method to simulate the oil spill, there are a lot of options for the size of characteristic oil-particle and the method of changing oil slick into particles. Effects by different sizes of characteristic oilparticle were analyzed and compared. Results showed that under the same total volume of oil spills, the simulated area of oil spill increased by 14%~25% as the size of the characteristic oil-particle decreased by 50% and simulated area of oil spill increased by 31%~43% as the size of the characteristic oil-particle decreased by 10 times. Two-stage method was proposed to improve the oil-particle method which has a shortage in calculating oil spill area, however, the two-stage method evenly distributed the changing oil slick into particles in space, while the oil film should be normal distributed in space. The method of changing oil slick into particles has been improved, and results show that the two methods are not much different in calculating the oil spill area, but the method improves the calculation of the slickness of oil film calculation according to the actual instance.%在应用油粒子法模拟溢油运动时,特征油粒子在体积和油膜粒子化方法上可以有多种选择,文章就不同特征体积的油粒子对溢油面积的影响进行了分析和比较,结果显示,溢油量相同时,特征油粒子的体积每减小一倍,溢油扩散面积增加14%-25%,减小10倍时,达到31%-43%.针对溢油扩散面积计算不足的情况,已有学者提出用"两阶段"法进行改进.但"两阶段"法在油膜粒子化时采用的是平均分布,而此时的油膜应为正态分布,即中间厚,向四周逐渐减少.因此,文章应用正态分布法对油膜粒子化进行改进,得到自己的油膜粒子化方法.结果显示,两方法在计算溢油面积时并无太大的差别,但在油膜厚度计算方面,文章方法更接近实际情况.

  4. Research into basic rocks types

    International Nuclear Information System (INIS)

    Teollisuuden Voima Oy (TVO) has carried out research into basic rock types in Finland. The research programme has been implemented in parallel with the preliminary site investigations for radioactive waste disposal in 1991-1993. The program contained two main objectives: firstly, to study the properties of the basic rock types and compare those with the other rock types under the investigation; secondly, to carry out an inventory of rock formations consisting of basic rock types and suitable in question for final disposal. A study of environmental factors important to know regarding the final disposal was made of formations identified. In total 159 formations exceeding the size of 4 km2 were identified in the inventory. Of these formations 97 were intrusive igneous rock types and 62 originally extrusive volcanic rock types. Deposits consisting of ore minerals, industrial minerals or building stones related to these formations were studied. Environmental factors like natural resources, protected areas or potential for restrictions in land use were also studied

  5. Source rock potential in Pakistan

    Energy Technology Data Exchange (ETDEWEB)

    Raza, H.A. (Hydrocarbon Development Institute of Pakistan, Islamabad (Pakistan))

    1991-03-01

    Pakistan contains two sedimentary basins: Indus in the east and Balochistan in the west. The Indus basin has received sediments from precambrian until Recent, albeit with breaks. It has been producing hydrocarbons since 1914 from three main producing regions, namely, the Potwar, Sulaisman, and Kirthar. In the Potwar, oil has been discovered in Cambrian, Permian, Jurassic, and Tertiary rocks. Potential source rocks are identified in Infra-Cambrian, Permian, Paleocene, and Eocene successions, but Paleocene/Eocene Patala Formation seems to be the main source of most of the oil. In the Sulaiman, gas has been found in Cretaceous and Tertiary; condensate in Cretaceous rocks. Potential source rocks are indicated in Cretaceous, Paleocene, and Eocene successions. The Sembar Formation of Early Cretaceous age appears to be the source of gas. In the Kirthar, oil and gas have been discovered in Cretaceous and gas has been discovered in paleocene and Eocene rocks. Potential source rocks are identified in Kirthar and Ghazij formations of Eocene age in the western part. However, in the easter oil- and gas-producing Badin platform area, Union Texas has recognized the Sembar Formation of Early Cretaceous age as the only source of Cretaceous oil and gas. The Balochistan basin is part of an Early Tertiary arc-trench system. The basin is inadequately explored, and there is no oil or gas discovery so far. However, potential source rocks have been identified in Eocene, Oligocene, Miocene, and Pliocene successions based on geochemical analysis of surface samples. Mud volcanoes are present.

  6. Preparation of resistance reducing agent in slick-water fracturing and characteristic research%滑溜水压裂液中减阻剂的制备及特性研究

    Institute of Scientific and Technical Information of China (English)

    刘通义; 向静; 赵众从; 林波; 戴秀兰; 黄趾海; 张立丰

    2013-01-01

    采用反相微乳液法制备了一种用于滑溜水压裂液中的水溶性减阻剂,对减阻剂的粒径大小分布、重均分子量、降阻率和悬砂能力进行了测试.结果表明,减阻剂粒径小,分布窄,分子量高[Mw=(2.08±0.65)×107 g/mol],具备高分子减阻的特性;向清水中加入0.05%的减阻率,减阻率可达55%,并且具有一定的携砂能力.因此,该减阻剂的应用能很好的降低压裂施工摩阻、减小泵功、适当提高砂比,有助于非常规低渗储层的开采.%A water soluble DRA is prepared by inverse micro-emulsion polymerization, which can be applied to slick-water fracturing. The particle size distribution of DRA, weight average molecular weight,drag reduction efficiency and suspension property were tested. The results showed that the DRA has small size and narrow size distribution,higher molecular weight[Mw = (2.08 ±0.65) × 107 g/mol] ,it has drag reduction characteristics of polymer; the resistance-reducing is about 55% when addition of 0. 05% DRA to clean water can reduce friction and it also has the prop-carrying capacity. Therefore, the DRA can applied to slick-water fracturing quite well, thus it can reduce fracturing friction, decrease pump power, properly increasing sand ratio,this performance helpful to the development of low permeable formation.

  7. Role of Rho-Rock pathways induced by angiotensin Ⅱ in hepatic stellate cell contraction%Rho-Rock通路在血管紧张素Ⅱ诱导肝星状细胞收缩中的作用

    Institute of Scientific and Technical Information of China (English)

    张小兰; 肖冰; 李旭; 黄茂梁; 孟莹; 李鹰飞; 王媛媛; 宋卫兵

    2008-01-01

    Objective To investigate the mechanism of Ca2+-independent pathways mediated by Rho-kinase in contraction of hepatic steLlate cells (HSCs) induced by angiotonin Ⅱ (Ang )Ⅱ. Methods Human HSCs of the line HSC-T6 were cultured and randomly divided into 6 groups: negative control group, AngⅡ group treated by Ang Ⅱ 10 μmol/L for 15 min, Ang Ⅱ + irbesantan (Ang Ⅱ receptor inhibitor) group, exposed to irbesantan for 60 rain prior to Ang Ⅱ treatment, Ang Ⅱ + Y27632 (Rho kinase specific inhibitor) exposed to Y27632 for 60 min prior to Ang Ⅱ treatment, Ang Ⅱ + ML-7 (myosin fight chain kinase specific inhibitor) + saturo (protein kinase C specific inhibitor) group exposed to stauro for 60 min prior to Ang Ⅱ treatment, and Ang Ⅱ + Y27632 + ML-7 + stauro group, exposed to Y27632 and stauro for 60 min prior to Ang Ⅱ treatment. The cell contraction was detected by sillcone-tubber-membrane cultivation directly. The protein levels of MLC and phosphorylated MLC were detected by Western blotting 5, 15, 30, 60, and 120 min after Ang Ⅱ treatment. RT-PCR was used to detect the expression of Rock?., RhoAGTP, and RhoGEF in Ca2+- independent pathways mediated by Rho-kinage. Results The silicone-rubber- membrane covered by Ang Ⅱ treated HSCs showed obvious wrinkles indicating the contraction of HSCs. The ratios of phosphorylated MLC protein at the time pints 5, 15, 30, 60, and120 min of the Ang Ⅱ group to the control group (0 min)were 11.7±0. 1, 26.9±0.1, 11.2 ±0.1, 4.1 ±0. 1, and 1.0±0.1, showing that Ang Ⅱ increased the phosphorylated MLC protein level time-dependently with the peak level at the time point of 15 minutes. The levels of phosphorylated MLC protein of the Ang Ⅱ + irbesartan and Ang Ⅱ + Y27632 groups were (1.12±0.09)and (1.22±0.10) respectively, both significantly lower than that of the Ang Ⅱ group (1.33±0.06, both P<0.01). The level of phosphorylated MLC protein of the Ang Ⅱ + ML-7 + stauro group was (1.43 ± 0

  8. Dynamic rock fragmentation: thresholds for long runout rock avalanches

    Directory of Open Access Journals (Sweden)

    E.T. Bowman

    2014-10-01

    Full Text Available The dynamic fragmentation of rock within rock avalanches is examined using the fragmentation concepts introduced by Grady and co-workers. The analyses use typical material values for weak chalk and limestone in order to determine theoretical strain rate thresholds for dynamic fragmentation and resulting fragment sizes. These are found to compare favourably with data obtained from field observations of long runout rock avalanches and chalk cliff collapses in spite of the simplicity of the approach used. The results provide insight as to the energy requirements to develop long runout behaviour and hence may help to explain the observed similarities between large rock avalanches and much smaller scale chalk cliff collapses as seen in Europe.

  9. Space Weathering of Lunar Rocks

    Science.gov (United States)

    Noble, S. K.; Keller, L. P.; Christoffersen, R.; Rahman, Z.

    2012-01-01

    All materials exposed at the lunar surface undergo space weathering processes. On the Moon, boulders make up only a small percentage of the exposed surface, and areas where such rocks are exposed, like central peaks, are often among the least space weathered regions identified from remote sensing data. Yet space weathered surfaces (patina) are relatively common on returned rock samples, some of which directly sample the surface of larger boulders. Because, as witness plates to lunar space weathering, rocks and boulders experience longer exposure times compared to lunar soil grains, they allow us to develop a deeper perspective on the relative importance of various weathering processes as a function of time.

  10. Anthropic Rock: a brief history

    Directory of Open Access Journals (Sweden)

    R. B. Cathcart

    2011-03-01

    Full Text Available Stone tool-making is a reductive process. Synthetic rock manufacturing, preeminently an additive process, will not for-ever be confined to only the Earth-biosphere. This brief focuses on humanity's ancient past, hodiernal and possible future even more massive than present-day creation of artificial rocks within our exploitable Solar System. It is mostly Earth-centric account that expands the factual generalities underlying the unique non-copyrighted systemic technogenic rock classification first publicly presented (to the American Geological Society during 2001, by its sole intellectual innovator, James Ross Underwood, Jr. His pioneering, unique exposition of an organization of this ever-increasingly important aspect of the Anthropic Rock story, spatially expansive material lithification, here is given an amplified discussion for the broader geo and space science social group-purpose of encouragement of a completer 21st Century treatment of Underwood's explicative subject-chart (Fig. 2.

  11. ROCK DEFORMATION. Final Progress Report

    Energy Technology Data Exchange (ETDEWEB)

    None

    2002-05-24

    The Gordon Research Conference (GRC) on ROCK DEFORMATION was held at II Ciocco from 5/19/02 thru 5/24/02. Emphasis was placed on current unpublished research and discussion of the future target areas in this field.

  12. Seismic response of rock joints and jointed rock mass

    International Nuclear Information System (INIS)

    Long-term stability of emplacement drifts and potential near-field fluid flow resulting from coupled effects are among the concerns for safe disposal of high-level nuclear waste (HLW). A number of factors can induce drift instability or change the near-field flow patterns. Repetitive seismic loads from earthquakes and thermal loads generated by the decay of emplaced waste are two significant factors. One of two key technical uncertainties (KTU) that can potentially pose a high risk of noncompliance with the performance objectives of 10 CFR Part 60 is the prediction of thermal-mechanical (including repetitive seismic load) effects on stability of emplacement drifts and the engineered barrier system. The second KTU of concern is the prediction of thermal-mechanical-hydrological (including repetitive seismic load) effects on the host rock surrounding the engineered barrier system. The Rock Mechanics research project being conducted at the Center for Nuclear Waste Regulatory Analyses (CNWRA) is intended to address certain specific technical issues associated with these two KTUs. This research project has two major components: (i) seismic response of rock joints and a jointed rock mass and (ii) coupled thermal-mechanical-hydrological (TMH) response of a jointed rock mass surrounding the engineered barrier system (EBS). This final report summarizes the research activities concerned with the repetitive seismic load aspect of both these KTUs

  13. Seismic response of rock joints and jointed rock mass

    Energy Technology Data Exchange (ETDEWEB)

    Ghosh, A.; Hsiung, S.M.; Chowdhury, A.H. [Southwest Research Inst., San Antonio, TX (United States). Center for Nuclear Waste Regulatory Analyses

    1996-06-01

    Long-term stability of emplacement drifts and potential near-field fluid flow resulting from coupled effects are among the concerns for safe disposal of high-level nuclear waste (HLW). A number of factors can induce drift instability or change the near-field flow patterns. Repetitive seismic loads from earthquakes and thermal loads generated by the decay of emplaced waste are two significant factors. One of two key technical uncertainties (KTU) that can potentially pose a high risk of noncompliance with the performance objectives of 10 CFR Part 60 is the prediction of thermal-mechanical (including repetitive seismic load) effects on stability of emplacement drifts and the engineered barrier system. The second KTU of concern is the prediction of thermal-mechanical-hydrological (including repetitive seismic load) effects on the host rock surrounding the engineered barrier system. The Rock Mechanics research project being conducted at the Center for Nuclear Waste Regulatory Analyses (CNWRA) is intended to address certain specific technical issues associated with these two KTUs. This research project has two major components: (i) seismic response of rock joints and a jointed rock mass and (ii) coupled thermal-mechanical-hydrological (TMH) response of a jointed rock mass surrounding the engineered barrier system (EBS). This final report summarizes the research activities concerned with the repetitive seismic load aspect of both these KTUs.

  14. 30 CFR 57.3203 - Rock fixtures.

    Science.gov (United States)

    2010-07-01

    ... grouting material shall not be used. (f) When rock bolts tensioned by torquing are used as a means of... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Rock fixtures. 57.3203 Section 57.3203 Mineral... Support-Surface and Underground § 57.3203 Rock fixtures. (a) For rock bolts and accessories addressed...

  15. Heterogeneous Impact of ROCK2 on Carotid and Cerebrovascular Function.

    Science.gov (United States)

    De Silva, T Michael; Kinzenbaw, Dale A; Modrick, Mary L; Reinhardt, Lindsey D; Faraci, Frank M

    2016-09-01

    Rho kinase (ROCK) has been implicated in physiological and pathophysiological processes, including regulation of vascular function. ROCK signaling is thought to be a critical contributor to cardiovascular disease, including hypertension and effects of angiotensin II (Ang II). Two isoforms of ROCK (1 and 2) have been identified and are expressed in vascular cells. In this study, we examined the importance of ROCK2 in relation to vessel function using several models and a novel inhibitor of ROCK2. First, incubation of carotid arteries with the direct RhoA activator CN-03 or Ang II impaired endothelium-dependent relaxation by ≈40% to 50% (PROCK isoforms) or the selective ROCK2 inhibitor SLX-2119. In contrast, SLX-2119 had little effect on contraction of carotid arteries to receptor-mediated agonists (serotonin, phenylephrine, vasopressin, or U46619). Second, in basilar arteries, SLX-2119 inhibited constriction to Ang II by ≈90% without significantly affecting responses to serotonin or KCl. Third, in isolated pressurized brain parenchymal arterioles, SLX-2119 inhibited myogenic tone in a concentration-dependent manner (eg, 1 μmol/L SLX-2119 dilated by 79±4%). Finally, SLX-2119 dilated small pial arterioles in vivo, an effect that was augmented by inhibition of nitric oxide synthase. These findings suggest that ROCK2 has major, but heterogeneous, effects on function of endothelium and vascular muscle. The data support the concept that aberrant ROCK2 signaling may be a key contributor to select aspects of large and small vessel disease, including Ang II-induced endothelial dysfunction. PMID:27432870

  16. Ellipsoidal anisotropy in elasticity for rocks and rock masses

    CERN Document Server

    Pouya, Ahmad

    2011-01-01

    One of the interesting features with the ellipsoidal models of anisotropy presented in this paper is their acceptance of analytical solutions for some of the basic elasticity problems. It was shown by Pouya (2000) and Pouya and Zaoui (2006) that many closed-form solutions for basic problems involving linear isotropic materials could be extended by linear transformation to cover a variety of "ellipsoidal" materials. This paper will describe two main varieties of ellipsoidal elastic models and show how well they fit the in situ data for sedimentary rocks; numerical homogenization results for several varieties of fractured rock masses will also be provided.

  17. Fracture characteristics in Japanese rock

    International Nuclear Information System (INIS)

    It is crucial for the performance assessment of geosphere to evaluate the characteristics of fractures that can be dominant radionuclide migration pathways from a repository to biosphere. This report summarizes the characteristics of fractures obtained from broad literature surveys and the fields surveys at the Kamaishi mine in northern Japan and at outcrops and galleries throughout the country. The characteristics of fractures described in this report are fracture orientation, fracture shape, fracture frequency, fracture distribution in space, transmissivity of fracture, fracture aperture, fracture fillings, alteration halo along fracture, flow-wetted surface area in fracture, and the correlation among these characteristics. Since granitic rock is considered the archetype fractured media, a large amount of fracture data is available in literature. In addition, granitic rock has been treated as a potential host rock in many overseas programs, and has JNC performed a number of field observations and experiments in granodiorite at the Kamaishi mine. Therefore, the characteristics of fractures in granitic rock are qualitatively and quantitatively clarified to some extent in this report, while the characteristics of fractures in another rock types are not clarified. (author)

  18. Two functional polymorphisms of ROCK2 enhance arterial stiffening through inhibiting its activity and expression.

    Science.gov (United States)

    Liao, Yi-Chu; Liu, Ping-Yen; Lin, Hsiu-Fen; Lin, Wen-Yi; Liao, James K; Juo, Suh-Hang H

    2015-02-01

    Derangement of Rho-associated kinases (ROCKs) has been related to coronary artery disease and stroke. ROCK2, rather than ROCK1, plays a predominant role in vascular contractility. The present study aims to test (1) the associations between ROCK2 single nucleotide polymorphisms (SNPs) and arterial stiffness, and (2) the molecular mechanism accounting for their effects. Stiffness parameters including beta (β), elasticity modulus (Ep) and pulse wave velocity (PWV) were obtained by carotid ultrasonography. Seven tagging SNPs of ROCK2 were initially genotyped in 856 subjects and significant SNPs were replicated in another group of 527 subjects. Two SNPs in complete linkage disequilibrium were found to be significantly associated with arterial stiffness. The major alleles of rs978906 (A allele) and rs9808232 (C allele) were associated with stiffer arteries. SNP rs978906 was predicted to influence microRNA(miR)-1183 binding to ROCK2, while rs9808232 causes amino acid substitution. To determine their functional impact, plasmid constructs carrying different alleles of the significant SNPs were created. Compared to rs978906G-allele constructs, cells transfected with rs978906A-allele constructs had higher baseline luciferase activities and were less responsive to miR-1183 changes. Oxidized-low density lipoprotein (Ox-LDL) suppressed miR-1183 levels and increased ROCK2 protein amounts. For rs9808232, cells transfected with C-allele constructs had significantly higher ROCK activities than those with A-allele constructs. Leukocyte ROCK activities were further measured in 52 healthy subjects. The average ROCK activity was highest in human subjects with CC genotype at rs9808232, followed by those with AC and lowest in AA. Taken together, the present study showed that two functional SNPs of ROCK2 increase susceptibility of arterial stiffness in the Chinese population. Non-synonymous SNP rs9808232 influences ROCK2 activity, while 3' UTR SNP rs978906 affects the ROCK2 protein

  19. Uranium endowments in phosphate rock

    International Nuclear Information System (INIS)

    This study seeks to identify and specify the components that make up the prospects of U recovery from phosphate rock. A systems approach is taken. The assessment includes i) reviewing past recovery experience and lessons learned; ii) identifying factors that determine recovery; and iii) establishing a contemporary evaluation of U endowments in phosphate rock reserves, as well as the available and recoverable amounts from phosphate rock and phosphoric acid production. We find that in the past, recovery did not fulfill its potential and that the breakup of the Soviet Union worsened then-favorable recovery market conditions in the 1990s. We find that an estimated 5.7 million tU may be recoverable from phosphate rock reserves. In 2010, the recoverable tU from phosphate rock and phosphoric acid production may have been 15,000 tU and 11,000 tU, respectively. This could have filled the world U supply-demand gap for nuclear energy production. The results suggest that the U.S., Morocco, Tunisia, and Russia would be particularly well-suited to recover U, taking infrastructural considerations into account. We demonstrate future research needs, as well as sustainability orientations. We conclude that in order to promote investment and production, it seems necessary to establish long-term contracts at guaranteed prices, ensuring profitability for phosphoric acid producers. - Highlights: • We identify components that underlie the recovery of uranium from phosphate rock. • We estimate that 11,000 tU may have been recoverable from phosphoric acid in 2010. • Recovery is a resource conservation and environmental pollution control strategy. • To ensure investment in recovery technology, profitability needs to be secured

  20. Some rock mass assessment procedures for discontinuous crystalline rock

    International Nuclear Information System (INIS)

    Underground radioactive waste repositories place especially stringent demands on rock mass assessment and excavation design methodologies. As part of the Building Research Establishment's programme of research into geotechnical site assessment methodology, experiments were undertaken at an underground test site in granite at Troon, Cornwall, and in the Imperial College Laboratories. The results of discontinuity surveys showed that the borehole impression packer probe technique can provide an important source of information for radioactive waste repository site assessment. Similarly, borehole pressure tests can provide valuable data on discontinuity apertures and hydraulic conductivities and on rock mass permeabilities. A versatile, modular borehole pressure test system for use from restricted underground locations was developed and used successfully. Field tests gave values of equivalent parallel plate apertures and discontinuity hydraulic conductivities in similar ranges to those measured in laboratory tests on samples recovered from the site. Discontinuity normal stiffnesses were also measured successfully using the Terra Tek Geothermal Rock Mechanics Test System which proved itself capable of providing laboratory test data required to support geotechnical site assessment procedures for radioactive waste repositories in discontinuous rock. (author)

  1. Magnetic coupling at perovskite and rock-salt structured interfaces

    Energy Technology Data Exchange (ETDEWEB)

    Matvejeff, M., E-mail: mikko.matvejeff@picosun.com [Institute for Solid State Physics, University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, 277-8581 Chiba (Japan); Department of Chemistry, Aalto University, Kemistintie 1, 02150 Espoo (Finland); Ahvenniemi, E. [Department of Chemistry, Aalto University, Kemistintie 1, 02150 Espoo (Finland); Takahashi, R.; Lippmaa, M. [Institute for Solid State Physics, University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, 277-8581 Chiba (Japan)

    2015-10-05

    We study magnetic coupling between hole-doped manganite layers separated by either a perovskite or a rock-salt barrier of variable thickness. Both the type and the quality of the interface have a strong impact on the minimum critical barrier thickness where the manganite layers become magnetically decoupled. A rock-salt barrier layer only 1 unit cell (0.5 nm) thick remains insulating and is able to magnetically de-couple the electrode layers. The technique can therefore be used for developing high-performance planar oxide electronic devices such as magnetic tunnel junctions and quantum well structures that depend on magnetically and electronically sharp heterointerfaces.

  2. Grouting methodology in crystalline rock

    International Nuclear Information System (INIS)

    For this paper, an initial literature review was conducted to investigate the potential applications of grouting technology for geological disposal of high level radioactive waste (hereafter called geological disposal), and the potential grouting material for each application. The results show the necessity of using suspension grout, such as cement-based grout, during excavation work, especially deep underground. Next, the method to achieve highly effective seals in crystalline rock with cement grout is studied. To enhance the sealing quality, cement grout should penetrate into very fine fractures, e.g. less than 100 μm aperture. In the case of suspension grout, clogging with grout at the openings of rock fractures, especially fine fractures, tends to occur, which results in poor grout penetration. A laboratory experiment was conducted to investigate the clogging phenomenon; the results suggest that high injection pressures could be effective to prevent clogging. Finally, focusing on pre-excavation grouting for horizontal tunnels in crystalline rock, the effective grout hole patterns for achieving high quality sealing was studied. A series of theoretical calculations for water inflow and cost studies were conducted. The results indicate that a dense arrangement of grout holes in a relatively narrow area around a tunnel section, as practised in the Nordic countries, is favorable in hard crystalline rock. (author)

  3. Inelastic deformation in crystalline rocks

    Science.gov (United States)

    Rahmani, H.; Borja, R. I.

    2011-12-01

    The elasto-plastic behavior of crystalline rocks, such as evaporites, igneous rocks, or metamorphic rocks, is highly dependent on the behavior of their individual crystals. Previous studies indicate that crystal plasticity can be one of the dominant micro mechanisms in the plastic deformation of crystal aggregates. Deformation bands and pore collapse are examples of plastic deformation in crystalline rocks. In these cases twinning within the grains illustrate plastic deformation of crystal lattice. Crystal plasticity is governed by the plastic deformation along potential slip systems of crystals. Linear dependency of the crystal slip systems causes singularity in the system of equations solving for the plastic slip of each slip system. As a result, taking the micro-structure properties into account, while studying the overall behavior of crystalline materials, is quite challenging. To model the plastic deformation of single crystals we use the so called `ultimate algorithm' by Borja and Wren (1993) implemented in a 3D finite element framework to solve boundary value problems. The major advantage of this model is that it avoids the singularity problem by solving for the plastic slip explicitly in sub steps over which the stress strain relationship is linear. Comparing the results of the examples to available models such as Von Mises we show the significance of considering the micro-structure of crystals in modeling the overall elasto-plastic deformation of crystal aggregates.

  4. Contaminant migration in rock aquifers

    International Nuclear Information System (INIS)

    This work deals with fractured rock as a host for deposits of hazardous waste. A literature review of modelling approaches and methods for field investigations concerning flow and migration in fractured rock is given. The literature study on field observations shows that the water flow in fractured rock is unevenly distributed, which contradicts the porous medium approach. Some idealized examples are given to investigate where to find low hydraulic gradients. The ability of a laminar pipe-flow model to reproduce the hydrodynamic transport of contaminated groundwater in fractured rock is investigated. It is assumed that the cross-section areas in an ensemble of tubes have a gamma distribution. The model is applied to field tracer experiments at two sites. An attempt is made to model a fracture with irregular aperture as a two-dimensional stochastic process with known correlation structure. It is assumed that the fracture aperture is lognormally distributed, and that the flow is laminar. A particle following algorithm is applied. A comparison with the porous medium approach, and with the laminar pipe flow model is made. 135 refs, 41 figs, 4 tabs

  5. ROCKS & MINERALS DETERMINATION AND ANALYSIS

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    <正>20070252 Chen Meilan (Biological and Environmental College, Zhejiang Shuren University, Hangzhou 310015, China); Li Li Study on Adsorption of Phenol by Modified Organobentonite (Rock and Mineral Analysis, ISSN0254-5357, CN11-2131/TD, 24(4), 2005, p.259-261, 267, 6 illus., 1 table, 11 refs.) Key words: bentonite, benzene, adsorption

  6. ROCKS & MINERALS DETERMINATION AND ANALYSIS

    Institute of Scientific and Technical Information of China (English)

    2014-01-01

    <正>20140786Deng Zhenping(Institute of Karst Geology,Chinese Academy of Geological Sciences,Guilin 541004,China);Yang Wen-qiong Application of Stripping Voltammetry with a Solid Amalgam Electrode for Determination of Copper in a Tracer and Groundwater Tracing Experiment(Rock and Mineral Analy-

  7. Gas migration through crystalline rocks

    International Nuclear Information System (INIS)

    Fractured rocks have been considered as potential host rocks for the deep disposal of radioactive waste in a number of countries. The representative repository concepts involved: a) Low- and intermediate-level waste in water-saturated fractured rock. b) Spent fuel (or HLW) in water-saturated fractured rock. c) Spent fuel in unsaturated fractured tuff (Yucca Mountain). The key gas-related issues are likely to be different for these three repository concepts. Concept (a) typically involves the emplacement of packaged wastes in caverns or tunnels, probably backfilled with a cement grout, and perhaps involving structural concrete lining. The quantities of gas produced for a given volume of waste are expected to be larger than for spent fuel or high-level waste and may include radioactive gases whose release at the surface requires assessment for its potential radiological consequences. For this concept, understanding the mechanisms and effects of gas migration through the geosphere is important in repository performance assessment. For concept (b), the waste is typically contained in long-lasting canisters emplaced in holes lined with compacted bentonite. The bentonite barriers are intended to provide the main barrier to groundwater access to the waste, and the quantities of gas expected to be produced are predicted to be sufficiently small that the host rock is not expected to provide a serious obstacle to gas escape from the region of the canister. In this concept, the main barrier to gas migration is considered to be the bentonite buffer; gas migration through this is discussed in a companion paper. Concept (c) is unique in involving emplacement of wastes in unsaturated rock, well above the water table, in a semi-arid region at Yucca Mountain in Nevada. Here the two-phase flow issues relate primarily to the infiltration of water through the fractured rock from the surface, which may involve flow channelling and intermittent flow, and the generation of strongly heat

  8. A new-type flexible rock-shed under the impact of rock block: experimental investigation

    Directory of Open Access Journals (Sweden)

    S. Shi

    2013-08-01

    Full Text Available The main disadvantage of conventional concrete rock-shed is the need for a massive foundation due to the deadweight of the structure. In order to overcome such construction difficulty and to reduce costs, a new concept of flexible rock-shed is proposed in this paper. The flexible rock-shed is made of flexible nets held up by specially designed steel vaulted structure. An 1:1 prototype is manufactured and tested for functional evaluation with impact experiment. It is shown that the structure can stand for an impact energy of about 250 kJ without observable rupture of the flexible nets or cables and can be put into service again with some maintenances on the steel vaulted structure. Expermental data such as local strains, peak loads and impact times are recorded by dynamic strain gauges, load cells and high speed camera for structural analysis and some complementary suggestions of improving and designing are offered with respect to the joints and components.

  9. Investigations of some rock stress measuring techniques and the stress field in Norway

    Energy Technology Data Exchange (ETDEWEB)

    Hanssen, Tor Harald

    1997-12-31

    Rock stresses are important to the safe construction and operation of all man-made structures in rock, whether In mining, civil or petroleum engineering. The crucial issue is their relative magnitude and orientation. This thesis develops equipment and methods for further rock stress assessment and reevaluates existing overcoring rock stress measurements, and relates this information to the present geological setting. Both laboratory work and field work are involved. In the field, rock stresses are measured by the overcoring and the hydraulic fracturing technique. An observation technique for assessing likely high stresses is developed. The field data refer to several hydropower projects and to some offshore hydrocarbon fields. The principal sections are: (1) Tectonic setting in the western Fennoscandia, (2) Triaxial rock stress measurements by overcoring using the NTH cell (a strain gauge cell developed at the Norwegian technical university in Trondheim and based on the CSIR cell of the South African Council for Scientific and Industrial Research), (3) Laboratory testing of the NTH cell, (4) Quality ranking of stresses measured by the NTH cell, (4) Recalculated rock stresses and implications to the regional stress field, (5) Hydraulic fracturing stress measurements. 113 refs., 98 figs., 62 tabs.

  10. RhoA、RhoB/Rock1、Rock2蛋白分子在重度子(癎)前期患者的表达%The expressions of protein RhoA/RhoB ang Rock1/Rock2 in severe preeclampsia

    Institute of Scientific and Technical Information of China (English)

    盖立文

    2015-01-01

    目的 研究重度子(癎)前期(sPE)患者的胎盘组织中Rho亚家族蛋白A(RhoA)、Rho亚家族蛋白B(RhoB)/相关卷曲螺旋形成蛋白激酶1(R0ck1)、相关卷曲螺旋形成蛋白激酶2(Rock2)蛋白分子的表达,探讨其与重度子(癎)前期发病的机制.方法 采用免疫组织化学法检测重度子(癎)前期组及正常晚期妊娠组胎盘组织中的RhoA、RhoB/Rock1、Rock2蛋白分子的表达定位及差异.结果 RhoA蛋白与RhoB蛋白及Rock1蛋白与Rock2蛋白在正常晚期妊娠组和重度子(癎)前期组胎盘滋养细胞、内皮细胞及一些间质细胞的胞浆中均有表达,以合体滋养细胞胞浆中表达为主,而Rock1蛋白与Rock2蛋白胞核中少量表达.RhoA、RhoB、Rock1、Rock2蛋白在重度子(癎)前期组的表达显著高于正常晚期妊娠组(P<0.05).结论 RhoA、RhoB蛋白和其下游靶分子Rock1、Rock2组成的信号通路,在子(癎)前期的胎盘组织中呈高表达,可能参与了子(癎)前期的胎盘的滋养细胞侵袭障碍、胎盘的滋养细胞的凋亡、缺血及缺氧、血管的部分内皮细胞损伤及动脉血管痉挛的病理过程,提示其蛋白分子在重度子(癎)前期发病中起着重要作用.%Objective To investigate expressions of Ras homologue protein family A (RhoA)/RhoB and Rho-associated coiled coil Rho forming protein Kinase 1 (Rock1)/Rock2 in placenta tissues of severe preeclampsia (sPE) to clarify the molecular mechanisms of sPE.Methods The locations and expressions of RhoA/RhoB and Rock1/Rock2 between two groups were detected with immunohistochemistry.Results RhoA,RhoB,Rock1,and Rock2 were mainly distributed in cytoplasms of syncytiotrophoblasts,cytotrophoblast,endothelial cells,and endometrial stromal cells.Rock1 and Rock2 were less expressed in nucleus.The expression levels of RhoA,RhoB,Rock1,and Rock2 in sPE group were significantly higher than control group (P < 0.05).Conclusions The signal pathway that consists of upstream Rho

  11. Double-Edge Sword of Sustained ROCK Activation in Prion Diseases through Neuritogenesis Defects and Prion Accumulation.

    Science.gov (United States)

    Alleaume-Butaux, Aurélie; Nicot, Simon; Pietri, Mathéa; Baudry, Anne; Dakowski, Caroline; Tixador, Philippe; Ardila-Osorio, Hector; Haeberlé, Anne-Marie; Bailly, Yannick; Peyrin, Jean-Michel; Launay, Jean-Marie; Kellermann, Odile; Schneider, Benoit

    2015-08-01

    In prion diseases, synapse dysfunction, axon retraction and loss of neuronal polarity precede neuronal death. The mechanisms driving such polarization defects, however, remain unclear. Here, we examined the contribution of RhoA-associated coiled-coil containing kinases (ROCK), key players in neuritogenesis, to prion diseases. We found that overactivation of ROCK signaling occurred in neuronal stem cells infected by pathogenic prions (PrPSc) and impaired the sprouting of neurites. In reconstructed networks of mature neurons, PrPSc-induced ROCK overactivation provoked synapse disconnection and dendrite/axon degeneration. This overactivation of ROCK also disturbed overall neurotransmitter-associated functions. Importantly, we demonstrated that beyond its impact on neuronal polarity ROCK overactivity favored the production of PrPSc through a ROCK-dependent control of 3-phosphoinositide-dependent kinase 1 (PDK1) activity. In non-infectious conditions, ROCK and PDK1 associated within a complex and ROCK phosphorylated PDK1, conferring basal activity to PDK1. In prion-infected neurons, exacerbated ROCK activity increased the pool of PDK1 molecules physically interacting with and phosphorylated by ROCK. ROCK-induced PDK1 overstimulation then canceled the neuroprotective α-cleavage of normal cellular prion protein PrPC by TACE α-secretase, which physiologically precludes PrPSc production. In prion-infected cells, inhibition of ROCK rescued neurite sprouting, preserved neuronal architecture, restored neuronal functions and reduced the amount of PrPSc. In mice challenged with prions, inhibition of ROCK also lowered brain PrPSc accumulation, reduced motor impairment and extended survival. We conclude that ROCK overactivation exerts a double detrimental effect in prion diseases by altering neuronal polarity and triggering PrPSc accumulation. Eventually ROCK emerges as therapeutic target to combat prion diseases. PMID:26241960

  12. ROCK inhibition abolishes the establishment of the aquiferous system in Ephydatia muelleri (Porifera, Demospongiae).

    Science.gov (United States)

    Schenkelaars, Quentin; Quintero, Omar; Hall, Chelsea; Fierro-Constain, Laura; Renard, Emmanuelle; Borchiellini, Carole; Hill, April L

    2016-04-15

    The Rho associated coiled-coil protein kinase (ROCK) plays crucial roles in development across bilaterian animals. The fact that the Rho/Rock pathway is required to initiate epithelial morphogenesis and thus to establish body plans in bilaterians makes this conserved signaling pathway key for studying the molecular mechanisms that may control early development of basally branching metazoans. The purpose of this study was to evaluate whether or not the main components of this signaling pathway exist in sponges, and if present, to investigate the possible role of the regulatory network in an early branching non-bilaterian species by evaluating ROCK function during Ephydatia muelleri development. Molecular phylogenetic analyses and protein domain predictions revealed the existence of Rho/Rock components in all studied poriferan lineages. Binding assays revealed that both Y-27632 and GSK429286A are capable of inhibiting Em-ROCK activity in vitro. Treatment with both drugs leads to impairment of growth and formation of the basal pinacoderm layer in the developing sponge. Furthermore, inhibition of Em-Rock prevents the establishment of a functional aquiferous system, including the absence of an osculum. In contrast, no effect of ROCK inhibition was observed in juvenile sponges that already possess a fully developed and functional aquiferous system. Thus, the Rho/Rock pathway appears to be essential for the proper development of the freshwater sponge, and may play a role in various cell behaviors (e.g. cell proliferation, cell adhesion and cell motility). Taken together, these data are consistent with an ancestral function of Rho/Rock signaling in playing roles in early developmental processes and may provide a new framework to study the interaction between Wnt signaling and the Rho/Rock pathway. PMID:26944094

  13. ROCK inhibition abolishes the establishment of the aquiferous system in Ephydatia muelleri (Porifera, Demospongiae).

    Science.gov (United States)

    Schenkelaars, Quentin; Quintero, Omar; Hall, Chelsea; Fierro-Constain, Laura; Renard, Emmanuelle; Borchiellini, Carole; Hill, April L

    2016-04-15

    The Rho associated coiled-coil protein kinase (ROCK) plays crucial roles in development across bilaterian animals. The fact that the Rho/Rock pathway is required to initiate epithelial morphogenesis and thus to establish body plans in bilaterians makes this conserved signaling pathway key for studying the molecular mechanisms that may control early development of basally branching metazoans. The purpose of this study was to evaluate whether or not the main components of this signaling pathway exist in sponges, and if present, to investigate the possible role of the regulatory network in an early branching non-bilaterian species by evaluating ROCK function during Ephydatia muelleri development. Molecular phylogenetic analyses and protein domain predictions revealed the existence of Rho/Rock components in all studied poriferan lineages. Binding assays revealed that both Y-27632 and GSK429286A are capable of inhibiting Em-ROCK activity in vitro. Treatment with both drugs leads to impairment of growth and formation of the basal pinacoderm layer in the developing sponge. Furthermore, inhibition of Em-Rock prevents the establishment of a functional aquiferous system, including the absence of an osculum. In contrast, no effect of ROCK inhibition was observed in juvenile sponges that already possess a fully developed and functional aquiferous system. Thus, the Rho/Rock pathway appears to be essential for the proper development of the freshwater sponge, and may play a role in various cell behaviors (e.g. cell proliferation, cell adhesion and cell motility). Taken together, these data are consistent with an ancestral function of Rho/Rock signaling in playing roles in early developmental processes and may provide a new framework to study the interaction between Wnt signaling and the Rho/Rock pathway.

  14. 21 CFR 868.5180 - Rocking bed.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Rocking bed. 868.5180 Section 868.5180 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES ANESTHESIOLOGY DEVICES Therapeutic Devices § 868.5180 Rocking bed. (a) Identification. A rocking bed is a...

  15. Rock Art: Connecting to the Past.

    Science.gov (United States)

    Knipe, Marianne

    2001-01-01

    Presents an activity for fourth-grade students in which they learn about ancient art and create their own authentic-looking rock sculptures with pictograms, or painted images. Explains how the students create their own rocks and then paint a pictograph on the rocks with brown paint. (CMK)

  16. Differentiation and analysis on rock breaking characteristics of TBM disc cutter at different rock temperatures

    Institute of Scientific and Technical Information of China (English)

    谭青; 张桂菊; 夏毅敏; 李建芳

    2015-01-01

    In order to study rock breaking characteristics of tunnel boring machine (TBM) disc cutter at different rock temperatures, thermodynamic rock breaking mathematical model of TBM disc cutter was established on the basis of rock temperature change by using particle flow code theory and the influence law of interaction mechanism between disc cutter and rock was also numerically simulated. Furthermore, by using the linear cutting experiment platform, rock breaking process of TBM disc cutter at different rock temperatures was well verified by the experiments. Finally, rock breaking characteristics of TBM disc cutter were differentiated and analyzed from microscale perspective. The results indicate the follows. 1) When rock temperature increases, the mechanical properties of rock such as hardness, and strength, were greatly reduced, simultaneously the microcracks rapidly grow with the cracks number increasing, which leads to rock breaking load decreasing and improves rock breaking efficiency for TBM disc cutter. 2) The higher the rock temperature, the lower the rock internal stress. The stress distribution rules coincide with the Buzin Neske stress circle rules: the maximum stress value is below the cutting edge region and then gradually decreases radiant around; stress distribution is symmetrical and the total stress of rock becomes smaller. 3) The higher the rock temperature is, the more the numbers of micro, tensile and shear cracks produced are by rock as well as the easier the rock intrusion, along with shear failure mode mainly showing. 4) With rock temperature increasing, the resistance intrusive coefficients of rock and intrusion power decrease obviously, so the specific energy consumption that TBM disc cutter achieves leaping broken also decreases subsequently. 5) The acoustic emission frequency remarkably increases along with the temperature increasing, which improves the rock breaking efficiency.

  17. Radionuclide fixation mechanisms in rocks

    International Nuclear Information System (INIS)

    In the safety evaluation of the radioactive waste disposal in geological environment, the mass balance equation for radionuclide migration is given. The sorption of radionuclides by geological formations is conventionally represented by the retardation of the radionuclides as compared with water movement. In order to quantify the sorption of radionuclides by rocks and sediments, the distribution ratio is used. In order to study quantitatively the long term behavior of waste radionuclides in geological environment, besides the distribution ratio concept in short term, slower radionuclide retention reaction involving mineral transformation should be considered. The development of microspectroscopic method for long term reaction path modeling, the behavior of iron during granite and water interaction, the reduction precipitation of radionuclides, radionuclide migration pathways, and the representative scheme of radionuclide migration and fixation in rocks are discussed. (K.I.)

  18. Kimberley rock art dating project

    International Nuclear Information System (INIS)

    The art's additional value, unequalled by traditionally recognised artefacts, is its permanent pictorial documentation presenting a 'window' into the otherwise intangible elements of perceptions, vision and mind of pre-historic cultures. Unfortunately it's potential in establishing Kimberley archaeological 'big picture' still remains largely unrecognised. Some of findings of the Kimberley Rock Art Dating Project, using AMS and optical stimulated luminescence (OSL) dating techniques, are outlined. It is estimated that these findings will encourage involvement by a greater diversity of specialist disciplines to tie findings into levels of this art sequence as a primary reference point. The sequence represents a sound basis for selecting specific defined images for targeting detailed studies by a range of dating technique. This effectively removes the undesirable ad hoc sampling of 'apparently old paintings'; a process which must unavoidably remain the case with researchers working on most global bodies of rock art

  19. Mechanism of Rock Burst Occurrence in Specially Thick Coal Seam with Rock Parting

    Science.gov (United States)

    Wang, Jian-chao; Jiang, Fu-xing; Meng, Xiang-jun; Wang, Xu-you; Zhu, Si-tao; Feng, Yu

    2016-05-01

    Specially thick coal seam with complex construction, such as rock parting and alternative soft and hard coal, is called specially thick coal seam with rock parting (STCSRP), which easily leads to rock burst during mining. Based on the stress distribution of rock parting zone, this study investigated the mechanism, engineering discriminant conditions, prevention methods, and risk evaluation method of rock burst occurrence in STCSRP through setting up a mechanical model. The main conclusions of this study are as follows. (1) When the mining face moves closer to the rock parting zone, the original non-uniform stress of the rock parting zone and the advancing stress of the mining face are combined to intensify gradually the shearing action of coal near the mining face. When the shearing action reaches a certain degree, rock burst easily occurs near the mining face. (2) Rock burst occurrence in STCSRP is positively associated with mining depth, advancing stress concentration factor of the mining face, thickness of rock parting, bursting liability of coal, thickness ratio of rock parting to coal seam, and difference of elastic modulus between rock parting and coal, whereas negatively associated with shear strength. (3) Technologies of large-diameter drilling, coal seam water injection, and deep hole blasting can reduce advancing stress concentration factor, thickness of rock parting, and difference of elastic modulus between rock parting and coal to lower the risk of rock burst in STCSRP. (4) The research result was applied to evaluate and control the risk of rock burst occurrence in STCSRP.

  20. The Rho GTPase Effector ROCK Regulates Cyclin A, Cyclin D1, and p27Kip1 Levels by Distinct Mechanisms

    OpenAIRE

    Croft, Daniel R.; Olson, Michael F.

    2006-01-01

    The members of the Rho GTPase family are well known for their regulation of actin cytoskeletal structures. In addition, they influence progression through the cell cycle. The RhoA and RhoC proteins regulate numerous effector proteins, with a central and vital signaling role mediated by the ROCK I and ROCK II serine/threonine kinases. The requirement for ROCK function in the proliferation of numerous cell types has been revealed by studies utilizing ROCK-selective inhibitors such as Y-27632. H...

  1. Gas migration through salt rocks

    International Nuclear Information System (INIS)

    Salt as a host rock for a repository for radioactive waste may appear as a layered formation as observed at the WIPP site in the USA or as domed salt, which is abundant in the northern part of central Europe. Planned or actual repository sites like Gorleben, Morsleben or Asse in Germany are located in such salt domes. They have risen up in geological time from Permian salt beds until their upward movement has come to an end. Rock salt exists under geological conditions as an extremely dry material with a residual moisture content well below 1 %. Due to its crystalline nature, its permeability and porosity are very low. In addition, because of its plastic behaviour under stress salt has a high self-healing capacity. In fact, under undisturbed conditions, rock salt is considered as impermeable (permeability less than 10-22 m2). This is demonstrated impressively by brine inclusions which have been included millions of years ago and are kept in place until today. Thus, in considering conditions for two phase flow, undisturbed salt neither offers sufficient water nor appropriate hydraulic properties for scenarios involving normal two-phase flow to occur. Therefore, there is a fundamental difference to other host rock material, in that long term safety analyses for waste repositories in salt have, in general, to assume accident scenarios or some kind of faulted conditions to produce a scenario where gas production and two-phase flow become relevant. The main focus of those safety analyses is on compacted crushed salt as backfill material, possibly on seals and plugs for emplacement rooms or borehole closures and on the engineering disturbed zone (EDZ). (author)

  2. Punk rock as popular theatre

    OpenAIRE

    Double, Oliver

    2007-01-01

    Punk rock performance consciously draws on popular theatre forms like music hall and stand-up comedy, as exemplified by the occasion when Max Wall appeared with Ian Dury at the Hammersmith Odeon. Oliver Double traces the historical and stylistic connections between punk, music hall and stand-up, and argues that punk shows can be considered a form of popular theatre in their own right. He examines a wide range of punk bands and performers- including Sex Pistols, Iggy Pop, Devo, ...

  3. Relative Permeability of Fractured Rock

    Energy Technology Data Exchange (ETDEWEB)

    Mark D. Habana

    2002-06-30

    Contemporary understanding of multiphase flow through fractures is limited. Different studies using synthetic fractures and various fluids have yielded different relative permeability-saturation relations. This study aimed to extend the understanding of multiphase flow by conducting nitrogen-water relative permeability experiments on a naturally-fractured rock from The Geysers geothermal field. The steady-state approach was used. However, steady state was achieved only at the endpoint saturations. Several difficulties were encountered that are attributed to phase interference and changes in fracture aperture and surface roughness, along with fracture propagation/initiation. Absolute permeabilities were determined using nitrogen and water. The permeability values obtained change with the number of load cycles. Determining the absolute permeability of a core is especially important in a fractured rock. The rock may change as asperities are destroyed and fractures propagate or st rain harden as the net stresses vary. Pressure spikes occurred in water a solute permeability experiments. Conceptual models of an elastic fracture network can explain the pressure spike behavior. At the endpoint saturations the water relative permeabilities obtained are much less than the nitrogen gas relative permeabilities. Saturations were determined by weighing and by resistivity calculations. The resistivity-saturation relationship developed for the core gave saturation values that differ by 5% from the value determined by weighing. Further work is required to complete the relative permeability curve. The steady-state experimental approach encountered difficulties due to phase interference and fracture change. Steady state may not be reached until an impractical length of time. Thus, unsteady-state methods should be pursued. In unsteady-state experiments the challenge will be in quantifying rock fracture change in addition to fluid flow changes.

  4. Uranium deposits in volcanic rocks

    International Nuclear Information System (INIS)

    Twenty-eight papers were presented at the meeting and two additional papers were provided. Three panels were organized to consider the specific aspects of the genesis of uranium deposits in volcanic rocks, recognition criteria for the characterization of such deposits, and approaches to exploration. The papers presented and the findings of the panels are included in the Proceedings. Separate abstracts were prepared for each of these papers

  5. Source rock hydrocarbons. Present status

    International Nuclear Information System (INIS)

    This report first presents the characteristics of conventional oil and gas system, and the classification of liquid and gaseous non conventional hydrocarbons, with the peculiar case of coal-bed methane. The authors then describe how source rock hydrocarbons are produced: production of shale oils and gases (horizontal drilling, hydraulic fracturing, exploitation) and of coal-bed methane and coal mine methane. In the next part, they address and discuss the environmental impact of source rock hydrocarbon production: installation footprint, water resource management, drilling fluids, fracturing fluids composition, toxicity and recycling, air pollution, induced seismicity, pollutions from other exploitation and production activities. They propose an overview of the exploitation and production of source rock gas, coal-bed gas and other non conventional gases in the world. They describe the current development and discuss their economic impacts: world oil context and trends in the USA, in Canada and other countries, impacts on the North American market, on the world oil industry, on refining industries, on the world oil balance. They analyse the economic impacts of non conventional gases: development potential, stakes for the world gas trade, consequence for gas prices, development opportunities for oil companies and for the transport sector, impact on CO2 emissions, macro-economic impact in the case of the USA

  6. The impact of mechanical properties of rock to the collision of rock piece

    Directory of Open Access Journals (Sweden)

    Borut Macuh

    2007-06-01

    Full Text Available The paper presents the analytical solution of the rock piece motion considering influences of geometrical and mechanical characteristics of rock mass on the arbitrary slope. The main objective of the paper is to determine the motion of the rock piece considering possibility of rock piece failure due to collision. Brief description of the analytical solution of the rock piece motion on a steep slope is given. The laboratory tests were performed to determine uniaxial compressive strength and elastic properties of the considered rock mass. Further, velocities that cause rock piece failure were determined. These maximum velocities indirectly belong to certain mass of rock piece and can be lower than velocities calculated in rock-fall analysis for certain slope geometry. Consequently, the energy magnitude is limited, because at certain velocity and mass of rock piece bigger pieces crash at collision.

  7. The physical principles of rock magnetism

    CERN Document Server

    Stacey, Frank

    1974-01-01

    Developments in Solid Earth Geophysics 5: The Physical Principles of Rock Magnetism explores the physical principles of rock magnetism, with emphasis on the properties of finely divided magnetic materials. It discusses the origin and stability of rock magnetizations, the role of remanent magnetism in interpreting magnetic surveys, magnetic anisotropy as an indicator of rock fabric, and the relationship between piezomagnetic changes and seismic activity. Organized into 13 chapters, this volume discusses the properties of solids, magnetite and hematite grains, and rocks with magnetite grains

  8. Dispersivity as an oil reservoir rock characteristic

    Energy Technology Data Exchange (ETDEWEB)

    Menzie, D.E.; Dutta, S.

    1989-12-01

    The main objective of this research project is to establish dispersivity, {alpha}{sub d}, as an oil reservoir rock characteristic and to use this reservoir rock property to enhance crude oil recovery. A second objective is to compare the dispersion coefficient and the dispersivity of various reservoir rocks with other rock characteristics such as: porosity, permeability, capillary pressure, and relative permeability. The dispersivity of a rock was identified by measuring the physical mixing of two miscible fluids, one displacing the other in a porous medium. 119 refs., 27 figs., 12 tabs.

  9. Petrology of unshocked crystalline rocks and shock effects in lunar rocks and minerals

    Science.gov (United States)

    Chao, E.C.T.; James, O.B.; Minkin, J.A.; Boreman, J.A.; Jackson, E.D.; Raleigh, C.B.

    1970-01-01

    On the basis of rock modes, textures, and mineralogy, unshocked crystalline rocks are classified into a dominant ilmenite-rich suite (subdivided into intersertal, ophitic, and hornfels types) and a subordinate feldspar-rich suite (subdivided into poikilitic and granular types). Weakly to moderately shocked rocks show high strain-rate deformation and solid-state transformation of minerals to glasses; intensely shocked rocks are converted to rock glasses. Data on an unknown calcium-bearing iron metasilicate are presented.

  10. Rock support system development test plan

    International Nuclear Information System (INIS)

    The Test Plan has been prepared to support design activities for the development of a rock support system for a Nuclear Waste Repository in Basalt (NWRB). The rock support system is assumed to consist of a combination of shotcrete and rock bolts. The seven testing activities include mix development and physical testing of shotcrete, durability testing of shotcrete, durability testing of rock bolt grouts, field tests on rock bolts, field testing of shotcrete, and heated room test. The objective of the Test Plan is to develop required data through combined laboratory, field, and office studies for design and design validation of the rock support system. The overall Test Plan is developed to provide a logical progression from laboratory tests performed to characterize fundamental thermomechanical properties of shotcrete and grouts, to field tests on rock bolts and shotcrete, and in situ performance tests. 21 refs., 15 figs., 33 tabs

  11. Rock bending creep and disturbance effects

    Institute of Scientific and Technical Information of China (English)

    付志亮; 郑颖人; 刘元雪

    2008-01-01

    The bending creep and its disturbance effects of red sandstone rock beam and oil shale rock beam were studied by adopting the self-developed gravitation level style rock creep test machine and bending creep test system,and the constitutive equations were established.It is found that fracture morphology of rock beams under no disturbance load is regular,cracking position of fractures is on part of loading concentration,the crack starts from a neutral plane.However,fracture morphology of rock beams under disturbance load is irregular,cracking position of fractures deviates from a neutral plane.Delayed instability of rock beam occurs for some time under constant disturbance load.When disturbance load is beyond a certain range,suddenly instability of occurs rock beam in a certain time.The results show that there is a guiding significance for creep stability in the geotechnical engineering fields.

  12. Mineral artefacts mimicking microfossils in Archean rocks

    Science.gov (United States)

    Lepot, K.; Philippot, P.; Benzerara, K.

    2009-04-01

    Because prokaryotes populating the early Earth were structurally and morphologically very simple, it is difficult to obtain taxonomic information from microfossils, and even more problematic, to distinguish true fossils from abiotic objects. For example, many self-assembly processes associated with the precipitation of nanoscale minerals in the presence of organic compounds generate cell-like structures. Based on high resolution microscopy observations on natural samples, we describe three types of features common to Archean rocks and suggest that they represent microfossil-like artefacts. Using Scanning Electron Microscopy we have observed carbon-free silica inclusions in carbonate sediments that are very similar in size and shape (rods and spheres) to microorganisms. The common distribution of organic carbon at grain boundaries in those rocks indicate that such cell-like minerals, when coated by secondarily-migrated carbonaceous mater, could easily be mistaken for microfossils. The organisation and the micro- to nano-structure of bacteriomorphs might be even more confusing. We have observed chains of spheres that match in size and arrangement with some coccoid bacteria such as streptococci. Transmission Electron Microscopy (TEM) observation of Focused Ion Beam (FIB) sections cut through these spheres shows that they are composed of TiO2nanocrystallites partly rimmed or linked by nanoscale chlorite films. This assemblage creates smooth cell-like structures at the micron-scale. However, the absence of organic carbon in those structures as well as the observation of many similar TiO2 chains of spheres dispersed in volcanic glass shards argue against a biologic origin. Ambient inclusions trails also generate filamentous structures that can be mistaken for microfossils. (Knoll and Barghoorn, 1974) suggested that such pseudofossils could have formed by the displacement of a crystal (e.g. pyrite) in its mineral matrix owing to pressure solution processes linked to gas

  13. Hydraulic testing in crystalline rock

    International Nuclear Information System (INIS)

    Swedish Geolocical Company (SGAB) conducted and carried out single-hole hydraulic testing in borehole Fi 6 in the Finnsjoen area of central Sweden. The purpose was to make a comprehensive evaluation of different methods applicable in crystalline rocks and to recommend methods for use in current and scheduled investigations in a range of low hydraulic conductivity rocks. A total of eight different methods of testing were compared using the same equipment. This equipment was thoroughly tested as regards the elasticity of the packers and change in volume of the test section. The use of a hydraulically operated down-hole valve enabled all the tests to be conducted. Twelve different 3-m long sections were tested. The hydraulic conductivity calculated ranged from about 5x10-14 m/s to 1x10-6 m/s. The methods used were water injection under constant head and then at a constant rate-of-flow, each of which was followed by a pressure fall-off period. Water loss, pressure pulse, slug and drill stem tests were also performed. Interpretation was carried out using standard transient evaluation methods for flow in porous media. The methods used showed themselves to be best suited to specific conductivity ranges. Among the less time-consuming methods, water loss, slug and drill stem tests usually gave somewhat higher hydraulic conductivity values but still comparable to those obtained using the more time-consuming tests. These latter tests, however, provided supplementary information on hydraulic and physical properties and flow conditions, together with hydraulic conductivity values representing a larger volume of rock. (orig./HP)

  14. Hot Dry Rock; Geothermal Energy

    Energy Technology Data Exchange (ETDEWEB)

    None

    1990-01-01

    The commercial utilization of geothermal energy forms the basis of the largest renewable energy industry in the world. More than 5000 Mw of electrical power are currently in production from approximately 210 plants and 10 000 Mw thermal are used in direct use processes. The majority of these systems are located in the well defined geothermal generally associated with crustal plate boundaries or hot spots. The essential requirements of high subsurface temperature with huge volumes of exploitable fluids, coupled to environmental and market factors, limit the choice of suitable sites significantly. The Hot Dry Rock (HDR) concept at any depth originally offered a dream of unlimited expansion for the geothermal industry by relaxing the location constraints by drilling deep enough to reach adequate temperatures. Now, after 20 years intensive work by international teams and expenditures of more than $250 million, it is vital to review the position of HDR in relation to the established geothermal industry. The HDR resource is merely a body of rock at elevated temperatures with insufficient fluids in place to enable the heat to be extracted without the need for injection wells. All of the major field experiments in HDR have shown that the natural fracture systems form the heat transfer surfaces and that it is these fractures that must be for geothermal systems producing from naturally fractured formations provide a basis for directing the forthcoming but, equally, they require accepting significant location constraints on HDR for the time being. This paper presents a model HDR system designed for commercial operations in the UK and uses production data from hydrothermal systems in Japan and the USA to demonstrate the reservoir performance requirements for viable operations. It is shown that these characteristics are not likely to be achieved in host rocks without stimulation processes. However, the long term goal of artificial geothermal systems developed by systematic

  15. Lander and Mini Matterhorn rock

    Science.gov (United States)

    1997-01-01

    One of the two forward cameras aboard the Sojourner rover took this image of the Sagan Memorial Station on Sol 26. The angular resolution of the camera is about three milliradians (.018 degrees) per pixel, which is why the image appears grainy. The field of view of each rover camera is about 127 degrees horizontally and 90 degrees vertically.Features seen on the lander include (from left to right): the Atmospheric Structure Instrument/Meteorology Package (ASI/MET) mast with windsocks; the low-gain antenna mast, the Imager for Mars Pathfinder (IMP) on its mast at center; the disc-shaped high-gain antenna at right, and areas of deflated airbags. The dark circle on the lander body is a filtered vent that allowed air to escape during launch, and allowed the lander to repressurize upon landing. The high-gain antenna is pointed at Earth. The large rock Yogi, which Sojourner has approached and studied, as at the far right of the image. Mini Matterhorn is the large rock situated in front of the lander at left.The horizontal line at the center of the image is due to differences in light-metering for different portions of the image. The shadow of Sojourner and its antenna are visible at the lower section of the image. The antenna's shadow falls across a light-colored rock.Mars Pathfinder is the second in NASA's Discovery program of low-cost spacecraft with highly focused science goals. The Jet Propulsion Laboratory, Pasadena, CA, developed and manages and Mars Pathfinder mission for NASA's Office of Space Science, Washington, D.C. JPL is an operating division of the California Institute of Technology (Caltech). The Imager for Mars Pathfinder (IMP) was developed by the University of Arizona Lunar and Planetary Laboratory under contract to JPL. Peter Smith is the Principal Investigator.

  16. Big Bang Day : Physics Rocks

    CERN Multimedia

    Brian Cox; John Barrowman; Eddie Izzard

    2008-01-01

    Is particle physics the new rock 'n' roll? The fundamental questions about the nature of the universe that particle physics hopes to answer have attracted the attention of some very high profile and unusual fans. Alan Alda, Ben Miller, Eddie Izzard, Dara O'Briain and John Barrowman all have interests in this branch of physics. Brian Cox - CERN physicist, and former member of 90's band D:Ream, tracks down some very well known celebrity enthusiasts and takes a light-hearted look at why this subject can appeal to all of us.

  17. ROCKS & MINERALS DETERMINATION AND ANALYSIS

    Institute of Scientific and Technical Information of China (English)

    2015-01-01

    20150204 Abaydulla Alimjan(Department of Chemistry and Environmental Sciences,Kashgar Teachers College,Kashgar 844006,China);Cheng Chunying Non-Metallic Element Composition Analysis of Non-Ferrous Metal Ores from Oytagh Town,Xinjiang(Rock and Mineral Analysis,ISSN0254-5357,CN11-2131/TD,33(1),2014,p.44-50,5illus.,4tables,28refs.)Key words:nonferrous metals ore,nonmetals,chemical analysis,thermogravimetric analysis Anions in non-ferrous ore materials

  18. Numerical study of rock blasting

    Science.gov (United States)

    Stefanov, Yu. P.; Bakeev, R. A.; Yudin, A. S.; Kuznetsova, N. S.

    2015-10-01

    The paper presents numerical simulation results on fracture of a concrete block due to dynamic explosive loads applied to the walls of a blast hole. Considered in the study is the influence of the pulse shape and rock properties on the pattern of irreversible deformation and cracking. It is found that a fractured zone bounded by a plastically deformed contour always arises around the explosion site. Comparison of elastoplastic deformation and fracture induced in the concrete block by explosion pulses of different durations and amplitudes shows that shorter pulses with higher amplitudes and steeper rise times provide a higher blasting efficiency.

  19. Microcraters on Apollo 15 and 16 rocks

    Science.gov (United States)

    Morrison, D. A.; Mckay, D. S.; Fruland, R. M.; Moore, H. J.

    1973-01-01

    Microcrater frequency distributions, determined for 11 Apollo 16 rocks and three Apollo 15 rocks, fall into four categories. Category 1 rocks (68415, 68416, 62235) are angular, cratered on one side only, and have moderate crater densities. Category 2 rocks (60016, 66075, 61175) are subrounded, cratered on all sides, and have distributions suggestive of the steady state. Category 3 rocks (61015, 62295) are subangular and cratered on only one side, but the crater frequency distributions have some of the characteristics of category 2 rocks. Category 4 rocks (15015, 15017, 15076, 60335) are angular, cratered on only one side, and have moderated to very low crater densities. The crater frequency distributions of categories 1 and 4 have properties indicating the possibility of estimating the time they were exposed to micrometeor bombardment. Category 1 rocks appear to have been exposed for 2 to 3 m.y. These rocks, particularly 68415, 68416, and 69935, may be ejecta from South Ray Crater, indicating an age of 2 to 3 m.y. for South Ray Crater. Category 4 rocks have been exposed for much shorter periods.

  20. Infiltration Flow Path Distributions in Unsaturated Rocks

    Science.gov (United States)

    Tokunaga, T. K.; Olson, K. R.; Wan, J.

    2004-12-01

    Spatial distributions of infiltration flow paths through rock formations are complex networks that determine flow velocities, control rates of natural geochemical reactions in the subsurface, as well as rates of contaminant transport to underlying groundwater. Despite these important consequences, distributions of infiltration paths and locally fast seepage rates through rocks are not well understood. Laboratory-based studies on fractured rocks cannot easily be conducted on systems large enough to include sufficient fracture network complexity, so that inferences of field-scale flux distributions cannot be reliably made. Field-based studies to date have permitted quantification of only a small fraction of the flow distribution, typically while imposing extremely high fluxes, and therefore have not allowed comprehensive delineation of flow distributions expected under natural recharge. Based on hydraulic scaling considerations, we hypothesize that unsaturated flow path distributions in rock deposits will be similar to those occurring in fractured rock formations under low overall infiltration rates. Talus rock deposits and mine waste rock piles control flow and transport into their respective underlying groundwaters. All of these reasons motivated infiltration experiments in rock packs. Experiments have been conducted on 4 different rock types and system scales ranging from 1 to 46 rock layers. Our experiments showed that infiltration through rocks conforms to no previously reported behavior in soils, and that flow paths do not progressively converge into fewer and fewer flow paths. Instead, a fundamentally different hydraulic structure develops, having an exponential (geometric) flux distribution, with the characteristic scale determined by the characteristic rock size. Although the phenomena are very different, the evolution of flow path distributions and local seepage rate distributions is predictable based on a statistical mechanical model for energy

  1. Aespoe hard rock laboratory Sweden

    International Nuclear Information System (INIS)

    The aim of the new Aespoe hard rock laboratory is to demonstrate state of the art of technology and evaluation methods before the start of actual construction work on the planned deep repository for spent nuclear fuel. The nine country OECD/NEA project in the Stripa mine in Sweden has been an excellent example of high quality international research co-operation. In Sweden the new Aespoe hard rock laboratory will gradually take over and finalize this work. SKB very much appreciates the continued international participation in Aespoe which is of great value for the quality efficiency, and confidence in this kind of work. We have invited a number of leading experts to this first international seminar to summarize the current state of a number of key questions. The contributions show the great progress that has taken place during the years. The results show that there is a solid scientific basis for using this knowledge on site specific preparation and work on actual repositories. (au)

  2. Laboratory characterization of rock joints

    International Nuclear Information System (INIS)

    A laboratory characterization of the Apache Leap tuff joints under cyclic pseudostatic and dynamic loads has been undertaken to obtain a better understanding of dynamic joint shear behavior and to generate a complete data set that can be used for validation of existing rock-joint models. Study has indicated that available methods for determining joint roughness coefficient (JRC) significantly underestimate the roughness coefficient of the Apache Leap tuff joints, that will lead to an underestimation of the joint shear strength. The results of the direct shear tests have indicated that both under cyclic pseudostatic and dynamic loadings the joint resistance upon reverse shearing is smaller than that of forward shearing and the joint dilation resulting from forward shearing recovers during reverse shearing. Within the range of variation of shearing velocity used in these tests, the shearing velocity effect on rock-joint behavior seems to be minor, and no noticeable effect on the peak joint shear strength and the joint shear strength for the reverse shearing is observed

  3. Laboratory characterization of rock joints

    Energy Technology Data Exchange (ETDEWEB)

    Hsiung, S.M.; Kana, D.D.; Ahola, M.P.; Chowdhury, A.H.; Ghosh, A. [Southwest Research Inst., San Antonio, TX (United States). Center for Nuclear Waste Regulatory Analyses

    1994-05-01

    A laboratory characterization of the Apache Leap tuff joints under cyclic pseudostatic and dynamic loads has been undertaken to obtain a better understanding of dynamic joint shear behavior and to generate a complete data set that can be used for validation of existing rock-joint models. Study has indicated that available methods for determining joint roughness coefficient (JRC) significantly underestimate the roughness coefficient of the Apache Leap tuff joints, that will lead to an underestimation of the joint shear strength. The results of the direct shear tests have indicated that both under cyclic pseudostatic and dynamic loadings the joint resistance upon reverse shearing is smaller than that of forward shearing and the joint dilation resulting from forward shearing recovers during reverse shearing. Within the range of variation of shearing velocity used in these tests, the shearing velocity effect on rock-joint behavior seems to be minor, and no noticeable effect on the peak joint shear strength and the joint shear strength for the reverse shearing is observed.

  4. ROCK inhibition as a therapy for spinal muscular atrophy: understanding the repercussions on multiple cellular targets

    Directory of Open Access Journals (Sweden)

    Emmanuelle eCoque

    2014-08-01

    Full Text Available Spinal muscular atrophy (SMA is the most common genetic disease causing infant death, due to an extended loss of motoneurons. This neuromuscular disorder results from deletions and/or mutations within the surviving motor neuron 1 (SMN1 gene, leading to a pathological decreased expression of functional full-length SMN protein. Emerging studies suggest that the small GTPase RhoA and its major downstream effector Rho kinase (ROCK, which both play an instrumental role in cytoskeleton organization, contribute to the pathology of motoneuron diseases. Indeed, an enhanced activation of RhoA and ROCK has been reported in the spinal cord of an SMA mouse model. Moreover, the treatment of SMA mice with ROCK inhibitors leads to an increased lifespan as well as improved skeletal muscle and neuromuscular junction pathology, without preventing motoneuron degeneration. Although motoneurons are the primary target in SMA, an increasing number of reports show that other cell types inside and outside the central nervous system contribute to SMA pathogenesis. As administration of ROCK inhibitors to SMA mice was systemic, the improvement in survival and phenotype could therefore be attributed to specific effects on motoneurons and/or on other non-neuronal cell types. In the present review, we will present the various roles of the RhoA/ROCK pathway in several SMA cellular targets including neurons, myocytes, glial cells, cardiomyocytes and pancreatic cells as well as discuss how ROCK inhibition may ameliorate their health and function. It is most likely a concerted influence of ROCK modulation on all these cell types that ultimately lead to the observed benefits of pharmacological ROCK inhibition in SMA mice.

  5. Rock-property changes during reservoir compaction

    Energy Technology Data Exchange (ETDEWEB)

    Morita, N. (Conoco, Inc., Ponca City, OK (United States)); Gray, K.E. (Texas Univ., Austin, TX (United States)); Srouji, F.A.A.; Jogi, P.N. (Teleco Oilfield Services Inc., Meviden, CT (US))

    1992-09-01

    Deformations, absolute permeability, electrical resistivity, PV change, and compressional- and shear-wave velocities were measured for Berea sandstone under various loading paths at temperatures from 70 to 380{degrees} F. The experimental behavior was subdivided into five categories. The experimental results were analyzed for each category, and the analysis was used to construct semianalytical rock-property equations, are expressed in terms of strain components. This formalism is practical because strains are more directly related to rock properties that are stress components. This paper presents unique rock-property data, including axial and radial measurements with various loading paths and temperatures; semianalytical equations that accurately simulate rock properties under various loading paths up to rock failure; and realistic predictions of rock-property changes during reservoir compaction.

  6. Geochemical Characteristics and Metallogenesis of Volcanic Rocks as Exemplified by Volcanic Rocks in Ertix,Xinjiang

    Institute of Scientific and Technical Information of China (English)

    刘铁庚; 叶霖

    1997-01-01

    Volcanic rocks in Ertix,Xinjiang,occurring in the collision zone between the Siberia Plate and the Junggar Plate,are distributed along the Eritix River Valley in northern Xinjiang.The volcanic rocks were dated at Late Paleozoic and can be divided into the spilite-keratophyre series and the basalt-andesite series.The spilite-keratophyre series volcanic rocks occur in the Altay orogenic belt at the southwest margin of the Siberia Plate.In addition to sodic volcanic rocks.There are also associated potassic-sodic volcanic rocks and potassic volcanic rocks.The potassic-sodic volcanic rocks occur at the bottom of the eruption cycle and control the distribution of Pb and Zn deposits.The potassic volcanic rocks occur at the top of the eruption cycle and are associated with Au and Cu mineralizations.The sodic volcanic rocks occur in the middle stage of eruption cycle and control the occurrence of Cu(Zn) deposits.The basalt-andesite series volcanic rocks distributed in the North Junggar orogenic belt at the north margin of the Junggar-Kazakstan Plate belong to the potassic sodic volcain rocks.The volcanic rocks distributed along the Ulungur fault are relatively rich in sodium and poor in potassium and are predominated by Cu mineralization and associated with Au mineralization.Those volcanic rocks distributed along the Ertix fault are relatively rich in K and poor in Na,with Au mineralization being dominant.

  7. Wave generations from confined explosions in rocks

    OpenAIRE

    C. L. Liu; Ahrens, Thomas J.

    1998-01-01

    In order to record P- and S-waves generated from confined explosions in rocks in the laboratory, a method is developed based on the interactions between incident P- and SV-waves and free-surfaces of rocks. The relations between particle displacements of incident P- and SV-waves, and the strains measured using strain gauges attached on free-surfaces of rocks are analytically derived. P- and SV-waves generated from confined explosions in Bedford limestone are recorded.

  8. ROCK GLACIERS IN THE KOLYMA HIGHLAND

    OpenAIRE

    A. A. Galanin

    2015-01-01

    Based on remote mapping and field studies inGrand Rapids, Tumansky,Hasynsky,Del-Urechen Ridges as well as Dukchinsky and Kilgansky Mountain Massifs there were identified about 1160 landforms which morphologically are similar to the rock glaciers or they develop in close association with them. Besides tongue-shaped cirque rock glaciers originated due to ablation, a large number of lobate-shaped slope-associated rock glaciers were recognized. Significant quantity of such forms are developing wi...

  9. The rock resources of the Northern Emirates

    OpenAIRE

    Mitchell, Clive; Styles, Michael

    2011-01-01

    The Rock Resources of the Northern Emirates The United Arab Emirates (UAE) has vast resources of limestone and hard rock in the northern Emirates. These are currently exploited by quarrying companies to produce construction aggregate and raw material for the manufacture of cement, with a small amount being used to produce rock wool, dimension stone and mineral filler. The demand by industry for higher value mineral products that could be produced from these resources is mostly met by impor...

  10. Toe rock stability for rubble mound breakwaters

    OpenAIRE

    Baart, S.; Ebbens, R.; Nammuni-Krohn, J.; Verhagen, H.J.

    2010-01-01

    Present design tools, as found in the Rock Manual or Coastal Engineering Manual, for the determination of toe rock size for rubble mound breakwaters are based on test data with a large spread: data is relatively dispersed around the centre and descriptive equations have limited applicability ranges. New research has been undertaken to contribute to a more accurate description of toe rock stability. Flume tests have lead to an empirical design criterion for toe bunds in very shallow water base...

  11. Roof sounding device - A loose rock detector

    International Nuclear Information System (INIS)

    The US Bureau of Mines has developed a method and device designed to detect loose rock material in underground mines. The technology is designed to be an aid to mine workers in detecting hazardous roof conditions in underground mines which can complement or replace the traditional roof sounding techniques where the miner relies on experience to determine whether rock conditions are sound. The leading cause of accidents and fatalities in underground mines is falls of loose rock pieces or rock slabs from the mine roof. In previous research the Bureau of Mines found that loose rock, when impacted, vibrates at a much lower frequency than intact rock material. A major problem in determining rock stability using this technique has been the repeatability of the impact signal. This difficulty has been greatly reduced in the current design by measuring the power spectra contained in two separate frequency bands of the signal produced by striking the rock in question. The ratio of the energy contained in each band is computed. This process minimizes any striking force differences, producing accurate, repeatable results for solid rock as well as loose, drummy material. The prototype has been successfully tested in a variety of underground environments including coal, uranium, molybdenum, silver, and salt. The technology has ben investigated by the US Mine Health and Safety Administration and the Department of Energy for use in detecting detached tunnel lining areas in nuclear repositories. The paper will discuss the technique, applicable results, and future applications

  12. Kissing Mars Rocks with the Rover's RATs: An Educational Exercise to Understand Drilling Rocks on Mars

    Science.gov (United States)

    Williams, D. A.; Whelley, P. L.; Bleacher, J. E.; Cave, S. R.; Zabala-Aliberto, V. A.; Zabala, A. A.; Greeley, R.

    2007-03-01

    This abstract discusses an E/PO exercise we created for elementary school children that uses Hershey Kisses and straws to simulate the drilling of different rocks on Mars by the MER Rock Abrasion Tool.

  13. Prediction of rock brittleness using nondestructive methods for hard rock tunneling

    Directory of Open Access Journals (Sweden)

    Rennie B. Kaunda

    2016-08-01

    Full Text Available The material and elastic properties of rocks are utilized for predicting and evaluating hard rock brittleness using artificial neural networks (ANN. Herein hard rock brittleness is defined using Yagiz' method. A predictive model is developed using a comprehensive database compiled from 30 years' worth of rock tests at the Earth Mechanics Institute (EMI, Colorado School of Mines. The model is sensitive to density, elastic properties, and P- and S-wave velocities. The results show that the model is a better predictor of rock brittleness than conventional destructive strength-test based models and multiple regression techniques. While the findings have direct implications on intact rock, the methodology can be extrapolated to rock mass problems in both tunneling and underground mining where rock brittleness is an important control.

  14. Prediction of rock brittleness using nondestructive methods for hard rock tunneling

    Institute of Scientific and Technical Information of China (English)

    Rennie B. Kaunda; Brian Asbury

    2016-01-01

    The material and elastic properties of rocks are utilized for predicting and evaluating hard rock brit-tleness using artificial neural networks (ANN). Herein hard rock brittleness is defined using Yagiz’ method. A predictive model is developed using a comprehensive database compiled from 30 years’ worth of rock tests at the Earth Mechanics Institute (EMI), Colorado School of Mines. The model is sensitive to density, elastic properties, and P-and S-wave velocities. The results show that the model is a better predictor of rock brittleness than conventional destructive strength-test based models and mul-tiple regression techniques. While the findings have direct implications on intact rock, the methodology can be extrapolated to rock mass problems in both tunneling and underground mining where rock brittleness is an important control.

  15. Some influences of rock strength and strain rate on propagation of rock avalanches

    Science.gov (United States)

    Bowman, Elisabeth; Rait, Kim

    2016-04-01

    Rock avalanches are extreme and destructive mass movements in which large volumes of rock (typically >1 million cubic metres) travel at high speeds, covering large distances, and the occurrence of which is highly unpredictable. The "size effect" in rock avalanches, whereby those with larger volumes produce greater spreading efficiency (as defined by an increase in normalised runout) or lower farboschung angle (defined as the tangent of the ratio of fall height to runout length), is well known. Studies have shown that rock strength is a controlling factor in the mobility of rock avalanches - that is, mass movements involving lower strength rock are generally found to produce greater mobility as evidenced by the spread of deposits or low farboschung angle. However, there are conflicting ideas as to how and why this influence is manifested. This paper discusses different theories of rock comminution in light of numerical simulations of rock clasts undergoing normal and shear induced loading, experimental work on rock avalanche behaviour, and dynamic fracture mechanics. In doing so, we introduce the idea of thresholds of strain rate for the production of dynamic fragmentation (as opposed to pseudo-static clast crushing) that are based, inter alia, on static rock strength. To do this, we refer to data from physical models using rock analogue materials, field data on chalk cliff collapses, and field statistics from documented rock avalanches. The roles of normal and shear loading and loading rate within a rock avalanche are examined numerically using 3D Discrete Element Method models of rock clasts loaded to failure. Results may help to reconcile the observations that large rock avalanches in stronger materials tend not to fragment as much as those in weaker materials and also possess lower mobility, while small cliff collapses (typically > 1000 cubic metres) in weak chalk can exhibit rock avalanche-like behaviour at much smaller volumes.

  16. ROCKS & MINERALS DETERMINATION AND ANALYSIS

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    <正>20091570 Ge Yunjin(College of Geo-Resource and Information,China University of Petroleum,Dongying 257061,China);Chen Yong Advance in Low Temperature Phase Transition and Raman Spectrum Technique in Composition Determination of Fluid Inclusions(Rock and Mineral Analysis,ISSN0254-5357,CN11-2131/TD,27(3),2008,p.207-210,22 refs.)Key words:fluid inclusions,Raman spectraThe principle and development of low-temperature analytical techniques for fluid inclusions were expounded.The traditional low-temperature analytical technology mainly focused on the measurement of inorganic salt using congealed microthermometry,but now it is developed to semi-quantitative and quantitative analysis of fluid inclusions using in-situ cryogenic Raman spectrometry.

  17. Hydraulic conductivity of rock fractures

    International Nuclear Information System (INIS)

    Yucca Mountain, Nevada contains numerous geological units that are highly fractured. A clear understanding of the hydraulic conductivity of fractures has been identified as an important scientific problem that must be addressed during the site characterization process. The problem of the flow of a single-phase fluid through a rough-walled rock fracture is discussed within the context of rigorous fluid mechanics. The derivation of the cubic law is given as the solution to the Navier-Stokes equations for flow between smooth, parallel plates, the only fracture geometry that is amenable to exact treatment. The various geometric and kinetic conditions that are necessary in order for the Navier-Stokes equations to be replaced by the more tractable lubrication or Hele-Shaw equations are studied and quantified. Various analytical and numerical results are reviewed pertaining to the problem of relating the effective hydraulic aperture to the statistics of the aperture distribution. These studies all lead to the conclusion that the effective hydraulic aperture is always less than the mean aperture, by a factor that depends on the ratio of the mean value of the aperture to its standard deviation. The tortuosity effect caused by regions where the rock walls are in contact with each other is studied using the Hele-Shaw equations, leading to a simple correction factor that depends on the area fraction occupied by the contact regions. Finally, the predicted hydraulic apertures are compared to measured values for eight data sets from the literature for which aperture and conductivity data were available on the same fracture. It is found that reasonably accurate predictions of hydraulic conductivity can be made based solely on the first two moments of the aperture distribution function, and the proportion of contact area. 68 refs

  18. Permeability Evolution and Rock Brittle Failure

    Directory of Open Access Journals (Sweden)

    Sun Qiang

    2015-08-01

    Full Text Available This paper reports an experimental study of the evolution of permeability during rock brittle failure and a theoretical analysis of rock critical stress level. It is assumed that the rock is a strain-softening medium whose strength can be described by Weibull’s distribution. Based on the two-dimensional renormalization group theory, it is found that the stress level λ c (the ratio of the stress at the critical point to the peak stress depends mainly on the homogeneity index or shape parameter m in the Weibull’s distribution for the rock. Experimental results show that the evolution of permeability is closely related to rock deformation stages: the permeability has a rapid increase with the growth of cracks and their surface areas (i.e., onset of fracture coalescence point, and reaches the maximum at rock failure. Both the experimental and analytical results show that this point of rapid increase in permeability on the permeabilitypressure curve corresponds to the critical point on the stress-strain curve; for rock compression, the stress at this point is approximately 80% of the peak strength. Thus, monitoring the evolution of permeability may provide a new means of identifying the critical point of rock brittle fracture

  19. Rock Plasticity from Microtomography and Upscaling

    Institute of Scientific and Technical Information of China (English)

    Jie Liu; Reem Freij-Ayoub; Klaus Regenauer-Lieb

    2015-01-01

    We present a workflow for upscaling of rock properties using microtomography and percolation theory. In this paper we focus on a pilot study for assessing the plastic strength of rocks from a digital rock image. Firstly, we determine the size of mechanical representative volume ele-ment (RVE) by using upper/lower bound dissipation computations in accordance with thermody-namics. Then the mechanical RVE is used to simulate the rock failure at micro-scale using FEM. Two cases of different pressures of linear Drucker-Prager plasticity of rocks are computed to com-pute the macroscopic cohesion and the angle of internal friction of the rock. We also detect the criti-cal exponents of yield stress for scaling laws from a series of derivative models that are created by a shrinking/expanding algorithm. We use microtomographic data sets of two carbonate samples and compare the results with previous results. The results show that natural rock samples with irregular structures may have the critical exponent of yield stress different from random models. This unex-pected result could have significant ramifications for assessing the stability of solid materials with internal structure. Therefore our pilot study needs to be extended to investigate the scaling laws of strength of many more natural rocks with irregular microstructure.

  20. Rock Music and Korean Adolescent's Antisocial Behavior.

    Science.gov (United States)

    Kim, Inkyung; Kwak, Keumjoo; Chang, Geunyoung; Yang, Jinyoung

    The relationship between rock music preference and antisocial behavior among Korean adolescents was examined. The Korean versions of the Sensation Seeking Scale and the Antisocial Behavior Checklist were used to measure sensation seeking motivation and delinquency. Adolescents (N=1,079) were categorized as "rock/metal,""dance," or "ballad" based…

  1. Cenozoic volcanic rocks of Saudi Arabia

    Science.gov (United States)

    Coleman, R.G.; Gregory, R.T.; Brown, G.F.

    2016-01-01

    The Cenozoic volcanic rocks of Saudi Arabia cover about 90,000 km2, one of the largest areas of alkali olivine basalt in the world. These volcanic rocks are in 13 separate fields near the eastern coast of the Red Sea and in the western Arabian Peninsula highlands from Syria southward to the Yemen Arab Republic.

  2. High-temperature carbidization of carboniferous rocks

    Science.gov (United States)

    Goldin, B. A.; Grass, V. E.; Nadutkin, A. V.; Nazarova, L. Yu.

    2009-08-01

    Processes of thermal metamorphism of carboniferous rocks have been studied experimentally. The conditions of high-temperature interaction of shungite carbon with components of the contained rocks, leading to formation of carbide compounds, have been determined. The results of this investigation contribute to the works on searching for new raw material for prospective material production.

  3. Toe rock stability for rubble mound breakwaters

    NARCIS (Netherlands)

    Baart, S.; Ebbens, R.; Nammuni-Krohn, J.; Verhagen, H.J.

    2010-01-01

    Present design tools, as found in the Rock Manual or Coastal Engineering Manual, for the determination of toe rock size for rubble mound breakwaters are based on test data with a large spread: data is relatively dispersed around the centre and descriptive equations have limited applicability ranges.

  4. Sorption of cesium in intact rock

    Energy Technology Data Exchange (ETDEWEB)

    Puukko, E. [Univ. of Helsinki, Dept. of Chemistry (Finland)

    2014-04-15

    The mass distribution coefficient K{sub d} is used in performance assessment (PA) to describe sorption of a radionuclide on rock. The R{sub d} is determined using crushed rock which causes uncertainty in converting the R{sub d} values to K{sub d} values for intact rock. This work describes a method to determine the equilibrium of sorption on intact rock. The rock types of the planned Olkiluoto waste disposal site were T-series mica gneiss (T-MGN), T-series tonalite granodiorite granite gneiss (T-TGG), P-series tonalite granodiorite granite gneiss (P-TGG) and pegmatitic granite (PGR). These rocks contain different amount of biotite which is the main sorbing mineral. The sorption of cesium on intact rock slices was studied by applying an electrical field to speed up migration of cesium into the rock. Cesium is in the solution as a noncomplex cation Cs{sup +} and it is sorbed by ion exchange. The tracer used in the experiments was {sup 134}Cs. The experimental sorption on the intact rock is compared with values calculated using the in house cation exchange sorption model (HYRL model) in PHREEQC program. The observed sorption on T-MGN and T-TGG rocks was close to the calculated values. Two PGR samples were from a depth of 70 m and three samples were from a depth of 150 m. Cesium sorbed more than predicted on the two 70 m PGR samples. The sorption of Cs on the three 150 m PGR samples was small which was consistent with the calculations. The pegmatitic granite PGR has the smallest content of biotite of the four rock types. In the case of P-TGG rock the observed values of sorption were only half of the calculated values. Two kind of slices were cut from P-TGG drill core. The slices were against and to the direction of the foliation of the biotite rims. The sorption of cesium on P-TGG rock was same in both cases. The results indicated that there was no effect of the directions of the electric field and the foliation of biotite in the P-TGG rock. (orig.)

  5. Characteristics of fluid substitution in porous rocks

    Institute of Scientific and Technical Information of China (English)

    Li Shengjie

    2009-01-01

    Analysis of the effect of changes in fluid properties of rocks on the compressional-wave velocity VP and shear-wave velocity Vs is very important for understanding the rock physical properties, especially in oilfield exploration and development.The fluid substitution process was analyzed by using ultrasonic measurement and theoretical calculations.The results showed that the effect of fluid substitution on the rock elastic modulus was mainly controlled by fluid properties, saturation, and confining pressure.For a rock with specific properties and porosity, the result of theoretical prediction for fluid substitution accorded with the experimental result under high confining pressure (higher than 60 MPa for our experimental data), but failed to describe the trend of experimental result under low confining pressure and VP predicted by Gassmann's equation was higher than that measured by experiment.A higher porosity resulted in stronger sensitivity of the bulk modulus of saturated rocks to the change of fluid properties.

  6. A study of rock bolting failure modes

    Institute of Scientific and Technical Information of China (English)

    Cao Chen; Jan Nemcik; Ren Ting; Naj Aziz

    2013-01-01

    Rock bolting has advanced rapidly during the past 4 decades due to a better understanding of load transfer mechanisms and advances made in the bolt system technology.Bolts are used as permanent and temporary support systems in tunnelling and mining operations.A review of has indicated that three systems of reinforcement devices have evolved as part of rock bolt and ground anchor while the rock is not generally thought of as being a component of the reinforcement system.A classification of rock bolting reinforcement systems is presented,followed by the fundamental theory of the load transfer mechanism.The failure mode of two phases of rock bolting system is formularised.The failure modes of cable bolting are discussed using a bond strength model as well as an iterative method.Finally,the interfacial shear stress model for ribbed bar is introduced and a closed form solution is obtained using a tri-line stress strain relationship.

  7. Geochemistry of Granitoid Rocks from Zhejiang Province and Crustal Evolution—Ⅰ.Phanerozoic Granitoid Rocks

    Institute of Scientific and Technical Information of China (English)

    王一先; 赵振华; 等

    1998-01-01

    The Phanerozoic granitoid rocks include the Caledonian,Indosinian and Yenshanian granitoid rocks.The existence of Caledonian and Indosinian granites was evidenced by zircon U-Pb ages,The study of the characteristics of major,trace and rare-earth elements,isotopic composition and petrogenesis for the granitoid rocks has been made,The Caledonian and Indosinian granites were derived from partial melting of the Proterozoic basement rocks and the two tectonic activities were weak,The Yenshanian grantoid rocks were derived from mixing of mantle and crustal materials,It implies that the crustal accretion took place in Mesozoic time.

  8. Rock avalanches: significance and progress (Invited)

    Science.gov (United States)

    Davies, T. R.

    2013-12-01

    1. The probability distribution of landslide volumes follows a power-law indicating that large rock avalanches dominate the terrestrial sediment supply from mountains, and that their source area morphologies dominate mountain topography. 2. Large rock slope failures (~ 106 m3 or greater) often mobilise into rock avalanches, which can travel extraordinarily long distances with devastating effect. This hypermobility has been the subject of many investigations; we have demonstrated that it can be explained quantitatively and accurately by considering the energetics of the intense rock fragmentation that always occurs during motion of a large rock mass. 3. Study of rock avalanche debris psd shows that the energy used in creating new rock surface area during fragmentation is not lost to surface energy, but is recycled generating a high-frequency elastic energy field that reduces the frictional resistance to motion during runout. 4. Rock avalanches that deposit on glaciers can eventually form large terminal moraines that have no connection with any climatic event; unless these are identified as rock-avalanche-influenced they can confuse palaeoclimatic inferences drawn from moraine ages. Rock-avalanche-derived fines, however, can be identified in moraine debris up to ten thousand years old by the characteristic micron-scale agglomerates that form during intense fragmentation, and which are absent from purely climatically-induced moraines; there is thus a strong case for re-examining existing palaeoclimatic databases to eliminate potentially rock-avalanche-influenced moraine ages. 5. Rock avalanches (especially coseismic ones) are a serious hazard, being very destructive in their own right; they also block river valleys, forming landslide dams and potentially devastating dambreak floods, and subsequent severe decade-scale aggradation of downstream fans and floodplains. Rock avalanches falling into lakes or fiords can cause catastrophic tsunami that pose a serious risk to

  9. Rock weathering and Carbon cycle

    Science.gov (United States)

    Strozza, Patrick

    2010-05-01

    In the history of the Earth system, we can find indicators of hot or glacial periods, as well as brutal climatic change… How can we explain those climate variations on a geological timescale ? One of the causative agents is probably the fluctuation of atmospheric CO2 amounts, (gas responsible for the greenhouse effect). A concrete study of some CO2 fluxes between Earth system reservoirs (atmo, hydro and lithosphere) is proposed in this poster. Hydrogencarbonate is the major ion in river surface waters and its amount is so high that it can not be explained by a simple atmospheric Carbon diffusion. From a simple measurement of river HCO3- concentration, we can estimate the consumption of atmospheric CO2 that arises from carbonate and silicate weathering processes. Practical experiments are proposed. These are carried out in the local environment, and are conform to the curriculums of Chemistry and Earth sciences. These tests enable us to outline long-term Carbon cycles and global climatic changes. Key words : Erosion, rock weathering, CO2 cycle, Hydrogencarbonate in waters, climatic changes

  10. Rock stars for the day

    CERN Multimedia

    Stefania Pandolfi

    2015-01-01

    After a two-year hiatus, the CERN Hardronic Festival is back! On 8 August, ten CERN MusiClub bands will take to the stage for the popular event. As usual, the non-stop show will take place on the terrace of Restaurant 3 and will run until after midnight.   The Canettes Blues Band, part of the CERN MusiClub, performing live on the Music In The Park stage at the Montreux Jazz Festival, on 18 July 2013. A large range of musical styles will entertain the audience: from Irish folk, via 70s/80s/90s rock, to pop, blues and R&B. Alongside the music there will be activities for kids and food and drink stands. This year, the income from food sales will be donated to charity. The spirit that has characterised the festival ever since the first event in 1989 is that of a staff party. Any band who volunteers to play also helps to organise the event and set up the stage. “This is a really good thing because a festival that has been growing for many years requires a considerable amount of har...

  11. Terrestrial impact melt rocks and glasses

    Science.gov (United States)

    Dressler, B. O.; Reimold, W. U.

    2001-12-01

    The effects of meteorite and comet impact on Earth are rock brecciation, the formation of shock metamorphic features, rock melting, and the formation of impact structures, i.e. simple craters, complex craters, and multi-ring basins. Large events, such as the 65-Ma Chicxulub impact, are believed to have had catastrophic environmental effects that profoundly influenced the development of life on Earth. In this review, an attempt is made to summarize some of the voluminous literature on impact melting, one important aspect of planetary impact, provide some comments on this process, and to make suggestions for future research. The products of impact melting are glasses, impact melt rocks, and pseudotachylites. Our treatise deals mainly with the geological setting, petrography, and major-element chemistry of melt rocks and glasses. Impact glasses, in several petrographic aspects, are similar to volcanic glasses, but they are associated with shock metamorphosed mineral and rock fragments and, in places, with siderophile element anomalies suggestive of meteoritic contamination. They are found in allogenic breccia deposits within (fall-back 'suevite') and outside (fall-out 'suevite') impact craters and, as spherules, in distal ejecta. Large events, such as the K/T boundary Chicxulub impact, are responsible for the formation of worldwide ejecta horizons which are associated with siderophile element anomalies and shock metamorphosed mineral and rock debris. Impact glasses have a bulk chemical composition that is homogeneous but exemptions to this rule are common. On a microscopic scale, however, impact glasses are commonly strikingly heterogeneous. Tektites are glasses ejected from craters over large distances. They are characterized by very low water and volatile contents and element abundances and ratios that are evidence that tektites formed by melting of upper crustal, sedimentary rocks. Four tektite strewn-fields are known, three of which can be tied to specific impact

  12. Uranium deposits in magmatic and metamorphic rocks

    International Nuclear Information System (INIS)

    The association of uranium with certain types of magmatic and metamorphic rocks is well known. They have consequently been explored and studied quite extensively. In recent years interest in them has been eclipsed by the discovery of larger, lower cost deposits in other geological environments. Nonetheless, magmatic and metamorphic rocks continue to be important sources of uranium and large areas of the Earth's crust with such rocks are prospective locations for additional discoveries. As future exploration and development could be more difficult the full importance of individual deposits may not be recognized until after many years of investigation and experience. In addition to being important host rocks, magmatic and metamorphic rocks have been of considerable interest to uranium geologists as they are considered to be important source rocks for uranium and thus can lead to deposits nearby in other environments. Furthermore, these rocks provide important information on the geochemical cycle of uranium in the Earth's crust and mantle. Such information can lead to identification of uranium provinces and districts and to a basic understanding of processes of formation of uranium deposits. The International Atomic Energy Agency convened a Technical Committee Meeting on Uranium Deposits in Magmatic and Metamorphic Rocks. The meeting was held in Salamanca, Spain, from 29 September to 3 October 1986. It was followed by a two day field trip to uranium deposits in the Ciudad Rodrigo and Don Benito areas. The meeting was attended by 48 participants from 22 countries. Two panels were organized for discussion of the following topics: (1) ore deposit genesis and characterization and (2) exploration and resource assessment. The technical papers together with the panel reports form this publication. The scope and variety of the papers included and the panel reports provide a good coverage of current knowledge and thinking on uranium in magmatic and metamorphic rocks

  13. Determination and applications of rock quality designation (RQD)

    OpenAIRE

    Lianyang Zhang

    2016-01-01

    Characterization of rock masses and evaluation of their mechanical properties are important and challenging tasks in rock mechanics and rock engineering. Since in many cases rock quality designation (RQD) is the only rock mass classification index available, this paper outlines the key aspects on determination of RQD and evaluates the empirical methods based on RQD for determining the deformation modulus and unconfined compressive strength of rock masses. First, various methods for determinin...

  14. Research present situation and analysis on classification of rock drillability

    Institute of Scientific and Technical Information of China (English)

    Zhang Zhi-hong; MA Qin-yong

    2001-01-01

    Rock drillability reflects the drill bit fragments rock hardly or easily. At present, rock drillability classification indexes have rock single-axle compressive strength, point load intensity,fracture stress during chiseling, drill speed, chiseling specific work, acoustic parameter, cutting magnitude, and so on. Every index reflects rock drillability but isn't overall. It is feasible that using many indexes of fuzzy mathematics method etc. to evaluate rock drillability.

  15. Mechanic behavior of unloading fractured rock mass

    Institute of Scientific and Technical Information of China (English)

    YIN Ke; ZHANG Yongxing; WU Hanhui

    2003-01-01

    Under tension and shear conditions related to unloading of rock mass, a jointed rock mass model of linear elastic fracture mechanics is established. According to the model, the equations of stresses, strains and displacements of the region influenced by the crack but relatively faraway the crack (the distance between the research point and the center of the crack is longer than the length of crack) are derived. They are important for evaluating the deformation of cracked rock. It is demonstrated by the comparison between computational results of these theoretical equations and the observed data from unloading test that they are applicable for actual engineering.

  16. Rock types present in lunar highland soils

    Science.gov (United States)

    Reid, A. M.

    1974-01-01

    Several investigators have studied soils from the lunar highlands with the objective of recognizing the parent rocks that have contributed significant amounts of material to these soils. Comparing only major element data, and thus avoiding the problems induced by individual classifications, these data appear to converge on a relatively limited number of rock types. The highland soils are derived from a suite of highly feldspathic rocks comprising anorthositic gabbros (or norites), high alumina basalts, troctolites, and less abundant gabbroic (or noritic) anorthosites, anorthosites, and KREEP basalts.

  17. Acoustics in rock and pop music halls

    DEFF Research Database (Denmark)

    Adelman-Larsen, Niels Werner; Thompson, Eric Robert; Gade, Anders Christian

    2007-01-01

    The existing body of literature regarding the acoustic design of concert halls has focused almost exclusively on classical music, although there are many more performances of rhythmic music, including rock and pop. Objective measurements were made of the acoustics of twenty rock music venues in...... Denmark and a questionnaire was used in a subjective assessment of those venues with professional rock musicians and sound engineers. Correlations between the objective and subjective results lead, among others, to a recommendation for reverberation time as a function of hall volume. Since the bass...

  18. THEORIES OF ROCK BREAKAGE WITH EXPLOSIVES

    Directory of Open Access Journals (Sweden)

    Vinko Škrlec

    2014-12-01

    Full Text Available The prediction and observation of the nature and dimensions of damaged zones in the surrounding rock mass and understanding the mechanisms of fracturing and crushing of the rock mass with explosives is one of the most important parameters in blasting design in order to obtain preferred granulation and reduce damaging effects of blasting on the environment. An overview of existing rock breakage theories with the energy released by the detonation of explosives is given in this paper (the paper is published in Croatian.

  19. Acoustics in rock and pop music halls

    DEFF Research Database (Denmark)

    Larsen, Niels Werner; Thompson, Eric Robert; Gade, Anders Christian

    2007-01-01

    The existing body of literature regarding the acoustic design of concert halls has focused almost exclusively on classical music, although there are many more performances of rhythmic music, including rock and pop. Objective measurements were made of the acoustics of twenty rock music venues...... in Denmark and a questionnaire was used in a subjective assessment of those venues with professional rock musicians and sound engineers. Correlations between the objective and subjective results lead, among others, to a recommendation for reverberation time as a function of hall volume. Since the bass...

  20. Laboratory measurements of rock thermal properties

    DEFF Research Database (Denmark)

    Bording, Thue Sylvester; Balling, N.; Nielsen, S.B.

    The thermal properties of rocks are key elements in understanding and modelling the temperature field of the subsurface. Thermal conductivity and thermal diffusivity can be measured in the laboratory if rock samples can be provided. We have introduced improvements to the divided bar and needle...... probe methods to be able to measure both thermal conductivity and thermal diffusivity. The improvements we implement include, for both methods, a combination of fast numerical finite element forward modelling and a Markov Chain Monte Carlo inversion scheme for estimating rock thermal parameters...

  1. Sliding rocks on Racetrack Playa, Death Valley National Park: first observation of rocks in motion.

    Directory of Open Access Journals (Sweden)

    Richard D Norris

    Full Text Available The engraved trails of rocks on the nearly flat, dry mud surface of Racetrack Playa, Death Valley National Park, have excited speculation about the movement mechanism since the 1940s. Rock movement has been variously attributed to high winds, liquid water, ice, or ice flotation, but has not been previously observed in action. We recorded the first direct scientific observation of rock movements using GPS-instrumented rocks and photography, in conjunction with a weather station and time-lapse cameras. The largest observed rock movement involved > 60 rocks on December 20, 2013 and some instrumented rocks moved up to 224 m between December 2013 and January 2014 in multiple move events. In contrast with previous hypotheses of powerful winds or thick ice floating rocks off the playa surface, the process of rock movement that we have observed occurs when the thin, 3 to 6 mm, "windowpane" ice sheet covering the playa pool begins to melt in late morning sun and breaks up under light winds of -4-5 m/s. Floating ice panels 10 s of meters in size push multiple rocks at low speeds of 2-5 m/min. along trajectories determined by the direction and velocity of the wind as well as that of the water flowing under the ice.

  2. Bacterial life and dinitrogen fixation at a gypsum rock.

    Science.gov (United States)

    Boison, Gudrun; Mergel, Alexander; Jolkver, Helena; Bothe, Hermann

    2004-12-01

    The organisms of a bluish-green layer beneath the shards of a gypsum rock were characterized by molecular techniques. The cyanobacterial consortium consisted almost exclusively of Chroococcidiopsis spp. The organisms of the shards expressed nitrogenase activity (C2H2 reduction) aerobically and in light. After a prolonged period of drought at the rock, the cells were inactive, but they resumed nitrogenase activity 2 to 3 days after the addition of water. In a suspension culture of Chroococcidiopsis sp. strain PCC7203, C2H2 reduction required microaerobic conditions and was strictly dependent on low light intensities. Sequencing of a segment of the nitrogenase reductase gene (nifH) indicated that Chroococcidiopsis possesses the alternative molybdenum nitrogenase 2, expressed in Anabaena variabilis only under reduced O2 tensions, rather than the widespread, common molybdenum nitrogenase. The shards apparently provide microsites with reduced light intensities and reduced O2 tension that allow N2 fixation to proceed in the unicellular Chroococcidiopsis at the gypsum rock, unless the activity is due to minute amounts of other, very active cyanobacteria. Phylogenetic analysis of nifH sequences tends to suggest that molybdenum nitrogenase 2 is characteristic of those unicellular or filamentous, nonheterocystous cyanobacteria fixing N2 under microaerobic conditions only. PMID:15574902

  3. Volcanic and sedimentary-rock aquifers

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This data set represents the extent of the Volcanic and sedimentary-rock aquifers in the states of Montana, Wyoming, Idaho, Nevada, California, Oregon, and...

  4. Rock bed heat accumulators. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Riaz, M.

    1977-12-01

    The principal objectives of the research program on rock bed heat accumulators (or RBHA) are: (1) to investigate the technical and economic feasibility of storing large amounts of thermal energy (in the tens of MWt range) at high temperature (up to 500/sup 0/C) over extended periods of time (up to 6 months) using native earth or rock materials; (2) to conduct studies to establish the performance characteristics of large rock bed heat accumulators at various power and temperature levels compatible with thermal conversion systems; and (3) to assess the materials and environmental problems associated with the operation of such large heat accumulators. Results of the study indicate that rock bed heat accumulators for seasonal storage are both technically and economically feasible, and hence could be exploited in various applications in which storage plays an essential role such as solar power and total energy systems, district and cogeneration heating systems.

  5. FRACTAL PROPERTIES OF ROCK FRACTURE SURFACES

    Institute of Scientific and Technical Information of China (English)

    王金安; 谢和平; MarekA.KWASNIEWSKI

    1996-01-01

    To give a better understanding of the morphological features of rock fracture surfaces within the framework of fractal geometry, the fractal characters of the rough surfaces in" rock are analyzed according to the variogram method. The study elaborates the significance of the geometric parameters-fractal dimension D and the intercept A on a log-log plot to the surface structure. Investigation extends to the anisotropy and heterogeneity of rock fracture surfaces, and the scale effect on the fractal estimation. The present study indicates that fractal dimension alone may not be sufficient to characterize the surface roughness of rock joints. A reliable estimation should take into account the combination of D and A.

  6. Features definition exchange cations in sedimentary rocks.

    OpenAIRE

    Bilec'ka V.A.

    2008-01-01

    The research method of determination of exchange cations in calcareous sedimentary rocks of different extractants, the influence of the ratio between the solid and liquid phases on extrusion exchange cations.

  7. Features definition exchange cations in sedimentary rocks.

    Directory of Open Access Journals (Sweden)

    Bilec'ka V.A.

    2008-05-01

    Full Text Available The research method of determination of exchange cations in calcareous sedimentary rocks of different extractants, the influence of the ratio between the solid and liquid phases on extrusion exchange cations.

  8. Study on fault induced rock bursts

    Institute of Scientific and Technical Information of China (English)

    LI Zhi-hua; DOU Lin-ming; LU Cai-ping; MU Zong-long; CAO An-ye

    2008-01-01

    In order to study the rules of rock bursts caused by faults by means of mechanical analysis of a roof rock-mass balanced structure and numerical simulation about fault slip destabilization, the effect of coal mining operation on fault plane stresses and slip displacement were studied. The results indicate that the slip displacement sharply increases due to the decrease of normal stress and the increase of shear stress at the fault plane when the working face advances from the footwall to the fault itself, which may induce a fault rock burst. However, this slip displacement will be very small due to the increase of normal stress and the decrease of shear stress when the working face advances from the hanging wall to the fault itself, which results in a very small risk of a fault rock burst.

  9. Red Rock Lakes Wildlife Refuge : Reports : 1939

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This report for Red Rock Lakes National Wildlife Refuge during 1939 contains and inventory of migratory waterfowl, as well as weather reports, and general remarks...

  10. Gravitational stresses in anisotropic rock masses

    Science.gov (United States)

    Amadei, B.; Savage, W.Z.; Swolfs, H.S.

    1987-01-01

    This paper presents closed-form solutions for the stress field induced by gravity in anisotropic rock masses. These rocks are assumed to be laterally restrained and are modelled as a homogeneous, orthotropic or transversely isotropic, linearly elastic material. The analysis, constrained by the thermodynamic requirement that strain energy be positive definite, gives the following important result: inclusion of anisotropy broadens the range of permissible values of gravity-induced horizontal stresses. In fact, for some ranges of anisotropic rock properties, it is thermodynamically admissible for gravity-induced horizontal stresses to exceed the vertical stress component; this is not possible for the classical isotropic solution. Specific examples are presented to explore the nature of the gravity-induced stress field in anisotropic rocks and its dependence on the type, degree and orientation of anisotropy with respect to the horizontal ground surface. ?? 1987.

  11. ROCK GLACIERS IN THE KOLYMA HIGHLAND

    Directory of Open Access Journals (Sweden)

    A. A. Galanin

    2012-01-01

    Full Text Available Based on remote mapping and field studies inGrand Rapids, Tumansky,Hasynsky,Del-Urechen Ridges as well as Dukchinsky and Kilgansky Mountain Massifs there were identified about 1160 landforms which morphologically are similar to the rock glaciers or they develop in close association with them. Besides tongue-shaped cirque rock glaciers originated due to ablation, a large number of lobate-shaped slope-associated rock glaciers were recognized. Significant quantity of such forms are developing within the active neotectonic areas, in zones of seismic-tectonic badland and in association with active earthquakes-controlling faults. Multiplication of regional data on volcanic-ash-chronology, lichenometry, Schmidt Hammer Test, pollen spectra and single radiocarbon data, most of the active rock glaciers were preliminary attributed to the Late Holocene.

  12. Pre-Eocene rocks of Java, Indonesia

    Science.gov (United States)

    Ketner, Keith B.; Kastowo; Modjo, Subroto; Naeser, C.W.; Obradovich, J.D.; Robinson, Keith; Suptandar, Tatan; Wikarno

    1976-01-01

    The exposed pre-Eocene rocks of Java can be divided into two compound units for purposes of reconnaissance mapping and structural interpretation: a sedimentary sequence and melange. The sedimentary sequence consists of moderately deformed and little-metamorphosed conglomerate, sandstone, mudstone, claystone, chert, and limestone. The melange consists of a chaotic mechanical mixture of rocks identical to those of the sedimentary sequence and their metamorphic equivalents, such as schist, phyllite, quartzite, and marble. In addition, it contains a large proportion of quartz porphyry and smaller amounts of granite, basalt, gabbro, peridotite, pyroxenite, and serpentinite. The sedimentary sequence is at least partly of Early Cretaceous age and the melange is of Early Cretaceous to very early Paleocene age. They are overlain unconformably by Eocene rocks. The presence in the melange of blocks of quartz porphyry and granite is not easily reconcilable with current plate tectonic concepts in which the sites of formation of melange and plutonic rocks should be hundreds of kilometres apart.

  13. Characterization and behaviour of argillaceous rocks

    International Nuclear Information System (INIS)

    The main activities concerning characterization and behaviour of argillaceous rocks and their environment are presented. The studies are related to the technico-economic feasibility and the long-term safety of disposal of radioactive waste in argillaceous media. (author)

  14. Geology and Geochemistry of Reworking Gold Deposits in Intrusive Rocks of China—Ⅰ. Features of the Intrusive Rocks

    Institute of Scientific and Technical Information of China (English)

    王秀璋; 程景平; 等

    1998-01-01

    Most gold deposits in intrusive rocks were formed as a result of reworking processes.the intrusive rocks containing gold deposits and consisting of ultramafic-mafic,intermediateacid and alkaline rocks of the Archean,Proterozoic,Caledonian,Hercynian and Yenshanian periods occur in cratons,activated zones of cratons and fold belts.Among them,ultramaficmafic rocks,diorite,alkaline rocks,and anorthosite are products of remelting in the mantle or mantle-crust or mantle with crustal contamination,However,auriferous intermediate-acid rocks are products of metasomatic-remelting in auriferous volcainc rocks or auriferous volcanosedimentary rocks in the deep crust.

  15. Relating rock avalanche morphology to emplacement processes

    Science.gov (United States)

    Dufresne, Anja; Prager, Christoph; Bösmeier, Annette

    2015-04-01

    The morphology, structure and sedimentological characteristics of rock avalanche deposits reflect both internal emplacement processes and external influences, such as runout path characteristics. The latter is mainly predisposed by topography, substrate types, and hydrogeological conditions. Additionally, the geological setting at the source slope controls, e.g. the spatial distribution of accumulated lithologies and hence material property-related changes in morphology, or the maximum clast size and amount of fines of different lithological units. The Holocene Tschirgant rock avalanche (Tyrol, Austria) resulted from failure of an intensely deformed carbonate rock mass on the southeast face of a 2,370-m-high mountain ridge. The initially sliding rock mass rapidly fragmented as it moved towards the floor of the Inn River valley. Part of the 200-250 x 106 m3 (Patzelt 2012) rock avalanche debris collided with and moved around an opposing bedrock ridge and flowed into the Ötz valley, reaching up to 6.3 km from source. Where the Tschirgant rock avalanche spread freely it formed longitudinal ridges aligned along motion direction as well as smaller hummocks. Encountering high topography, it left runup ridges, fallback patterns (i.e. secondary collapse), and compressional morphology (successively elevated, transverse ridges). Further evidence for the mechanical landslide behaviour is given by large volumes of mobilized valley-fill sediments (polymict gravels and sands). These sediments indicate both shearing and compressional faulting within the rock avalanche mass (forming their own morphological units through, e.g. in situ bulldozing or as distinctly different hummocky terrain), but also indicate extension of the spreading landslide mass (i.e. intercalated/injected gravels encountered mainly in morphological depressions between hummocks). Further influences on its morphology are given by the different lithological units. E.g. the transition from massive dolomite

  16. Rock Bar BTR -liiketoimintasuunnitelma baariyrityksen perustamiseksi

    OpenAIRE

    Rieppo, Jani

    2015-01-01

    Laurea-ammattikorkeakoulu Tiivistelmä Laurea Leppävaara Hotelli- ja ravintola-alan liikkeenjohdon koulutusohjelma Rieppo, Jani Rock Bar BTR -liiketoimintasuunnitelma baariyrityksen perustamiseksi Vuosi 2015 Sivumäärä 58 Tämän toiminnallisen opinnäytetyön tarkoituksena on liiketoimintasuunnitelman laatiminen uudelle rock-baarille, jonka avaaminen Joensuuhun on suunnitelman laatijan toimesta mahdollista joskus tulevaisuudessa. Tavo...

  17. Rock mass response during high pressure grouting

    OpenAIRE

    Gothäll, Rikard

    2006-01-01

    The sealing of hard jointed rock by grouting involves several complicated mechanical systems. The result is a complex coupled system of hydro- logical and mechanical precesses. In order to determine the higher order effects of the resulting system the fracture deformations must be assessed. This requires a model that mimics the mechanical behaviour of not only fractures under normal load but also the entire rock mass system. This model indicates that there are two dominant regimes involved; a...

  18. Developing a Virtual Rock Deformation Laboratory

    Science.gov (United States)

    Zhu, W.; Ougier-simonin, A.; Lisabeth, H. P.; Banker, J. S.

    2012-12-01

    Experimental rock physics plays an important role in advancing earthquake research. Despite its importance in geophysics, reservoir engineering, waste deposits and energy resources, most geology departments in U.S. universities don't have rock deformation facilities. A virtual deformation laboratory can serve as an efficient tool to help geology students naturally and internationally learn about rock deformation. Working with computer science engineers, we built a virtual deformation laboratory that aims at fostering user interaction to facilitate classroom and outreach teaching and learning. The virtual lab is built to center around a triaxial deformation apparatus in which laboratory measurements of mechanical and transport properties such as stress, axial and radial strains, acoustic emission activities, wave velocities, and permeability are demonstrated. A student user can create her avatar to enter the virtual lab. In the virtual lab, the avatar can browse and choose among various rock samples, determine the testing conditions (pressure, temperature, strain rate, loading paths), then operate the virtual deformation machine to observe how deformation changes physical properties of rocks. Actual experimental results on the mechanical, frictional, sonic, acoustic and transport properties of different rocks at different conditions are compiled. The data acquisition system in the virtual lab is linked to the complied experimental data. Structural and microstructural images of deformed rocks are up-loaded and linked to different deformation tests. The integration of the microstructural image and the deformation data allows the student to visualize how forces reshape the structure of the rock and change the physical properties. The virtual lab is built using the Game Engine. The geological background, outstanding questions related to the geological environment, and physical and mechanical concepts associated with the problem will be illustrated on the web portal. In

  19. Quantitative Chemical Indices of Weathered Igneous Rocks

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    A study was conducted to compare the effectiveness of different weathering indices for characterising weathered igneous rocks of Hong Kong. Among eight chemical indices evaluated in this study, the Parker index has been found most suitable for a quantitative description of state of weathering. Based on geochemical results of 174 samples, the index decreases almost linearly with an increasing extent of weathering. The results enable a better understanding of the modification of geotechnical properties of igneous rocks associated with weathering processes.

  20. Preliminary rock mechanics laboratory: Investigation plan

    International Nuclear Information System (INIS)

    This document presents the rationale for rock mechanics laboratory testing (including the supporting analysis and numerical modeling) planned for the site characterization of a nuclear waste repository in salt. This plan first identifies what information is required for regulatory and design purposes, and then presents the rationale for the testing that satisfies the required information needs. A preliminary estimate of the minimum sampling requirements for rock laboratory testing during site characterization is also presented. Periodic revision of this document is planned

  1. Nuclear power in rock. Principal report

    International Nuclear Information System (INIS)

    In September 1975 the Swedish Government directed the Swedish State Power Board to study the question of rock-siting nuclear power plants. The study accounted for in this report aims at clarifying the advantages and disadvantages of siting a nuclear power plant in rock, compared to siting on ground level, considering reactor safety, war protection and sabotage. The need for nuclear power production during war situations and the closing down of nuclear power plants after terminated operation are also dealt with. (author)

  2. Rock Bands/Rock Brands: Mediation and Musical Performance in Post-liberalization Bangalore

    OpenAIRE

    Coventry, Chloe Louise

    2013-01-01

    This dissertation, based on twelve months of ethnographic research in Bangalore, India, examines the city's six decades-old rock music culture, a rapidly professionalizing musical genre that has been largely overlooked in studies of Indian popular music. Though historically an English-language genre, contemporary Indian rock is performed in myriad regional languages and comprises heavy metal, indie, folk rock, cover songs and a variety of other styles. Observing its predication on the histori...

  3. Petrologic and REE Geochemical Characters of Burnt Rocks

    Institute of Scientific and Technical Information of China (English)

    HUANG Lei; LIU Chiyang; YANG Lei; ZHAO Junfeng; FANG Jianjun

    2008-01-01

    The study of burnt rocks is beneficial to the discussion on the tectonic movement,paleoclimate and paleogeography that coal seams are subjected to after they were formed. In order to obtain the basic data on the features of the burnt rocks, a systematic study of petrology and REE geochemistry on burnt rocks in Shenmu, Northern Shaanxi Province has been done, using the methods of SEM, EDS, susceptibility measurements and ICP-MS. The burnt rocks are divided into two series in the section: the melted rocks and the baked rocks. SEM and EDS analyses reveal that all the minerals show burnt and melted traces, and there are no clay minerals except iliite found in the burnt rocks. Susceptibility measurements reveal that the burnt rocks have abnormally high susceptibility values,whereas a geochemical analysis shows that the REE distribution pattern of burnt rocks is similar to that of sedimentary rocks (initial rocks). In the longitudinal section, with increasing degree of burning (from baked rocks to melted rocks), the ΣREE gradually decreases, and the total REE of melted rocks is obviously lower than that of baked rocks. Besides, the melted rocks show apparent negative Ce anomalies, while the baked rocks show no anomaly of Ce, and sometimes even show positive anomalies.

  4. The Rock that Hit New York

    Energy Technology Data Exchange (ETDEWEB)

    Meade, Roger Allen [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Keksis, August Lawrence [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-10-03

    On January 12, 1975, a rock seemed to fall from the sky over New York State’s Schoharie County hitting the tractor of a local farmer, who was “preparing his fields for spring planting.” As the farmer later described the event to a reporter from the UFO INVESTIGATOR, the object glanced off the tractor, fell to the ground, and melted its way through a patch of ice that was two and one half inches thick. The farmer, Leonard Tillapaugh, called the county sheriff, Harvey Stoddard, who recovered the rock, noting that it “was still warm.” Why and how a sample of the rock came to Los Alamos is not known. However, it captivated a wide Laboratory audience, was subjected to rigorous testing and evaluation. Los Alamos used the scientific method in the manner promoted by Hynek. Did Los Alamos solve the mystery of the rock’s origin? Not definitively. Although the exact origin could not be determined, it was shown conclusively that the rock was not from outer space. With that said, the saga of Rock that hit New York came to an end. Nothing more was said or written about it. The principals involved have long since passed from the scene. The NICAP ceased operations in 1980. And, the rock, itself, has disappeared.

  5. Marine source rocks of New Zeland

    Energy Technology Data Exchange (ETDEWEB)

    Murray, A.P.; Norgate, C.; Summons, R.E. (Australian Geological Survey Organisation, Canberra (Australia)) (and others)

    1996-01-01

    Exploration in New Zealand is moving beyond the Taranaki Basin with its mainly terrestrial source rocks. Good to excellent quality marine source rocks exist and have generated oil in the Northland, East Coast W North Taranaki Basins. These high quality source rocks are Wespread throughout the late Cretaceous - Paleocene passive margin sequence in these basins as well in offshore Canterbury and the Great South Basin. This paper details the character, distribution, generative capacity and maturation behavior of the two main source units and shows how they can be correlated to the numerous seeps and oil impregnations found in the East Coast and Northland Basins. As well as being useful in basin modelling, kinetic maturation parameters for these two source rock facies help to explain differences in the biomarker and isotopic composition of seep oils and also explain trends in Rock Eval Tmax which are unrelated to maturity. In the East Coast Basin alone, the raw oil potential of the Waipawa Black Shale approaches 80 billion barrels. An understanding of the marine source rocks described here is crucial to evaluating the hydrocarbon prospectivity of New Zealand away from the Taranaki Basin.

  6. Marine source rocks of New Zeland

    Energy Technology Data Exchange (ETDEWEB)

    Murray, A.P.; Norgate, C.; Summons, R.E. [Australian Geological Survey Organisation, Canberra (Australia)] [and others

    1996-12-31

    Exploration in New Zealand is moving beyond the Taranaki Basin with its mainly terrestrial source rocks. Good to excellent quality marine source rocks exist and have generated oil in the Northland, East Coast W North Taranaki Basins. These high quality source rocks are Wespread throughout the late Cretaceous - Paleocene passive margin sequence in these basins as well in offshore Canterbury and the Great South Basin. This paper details the character, distribution, generative capacity and maturation behavior of the two main source units and shows how they can be correlated to the numerous seeps and oil impregnations found in the East Coast and Northland Basins. As well as being useful in basin modelling, kinetic maturation parameters for these two source rock facies help to explain differences in the biomarker and isotopic composition of seep oils and also explain trends in Rock Eval Tmax which are unrelated to maturity. In the East Coast Basin alone, the raw oil potential of the Waipawa Black Shale approaches 80 billion barrels. An understanding of the marine source rocks described here is crucial to evaluating the hydrocarbon prospectivity of New Zealand away from the Taranaki Basin.

  7. Impact of rock anisotropy on fracture development

    Institute of Scientific and Technical Information of China (English)

    Lianbo Zeng; Jiyong Zhao; Shengju Zhu; Weiliang Xiong; Yonghong He; Jianwen Chen

    2008-01-01

    Experiments on uniaxial and triaxial rock mechanics and rock acoustic emissions have been conducted for research on the impact of rock anisotropy on the development of the fractures of different directions by taking as an example the ultra-low-permeability sandstone reservoir in the Upper Triassic Yanchang Formation within the Ordos Basin. The experimental results prove the existence of anisotropy of the rock mechanical property in the different directions on the plane, which is the chief reason for the production of impacts on the development of different assemblages of fractures in the geological periods. The rock anisotropy usually restricts the development of one assemblage of conjugate shear fractures. The fractures in the Yanchang Formation within the Ordos Basin are mainly shear fractures that formed under two tectonic actions. Theoretically, here, four assemblages of shear fractures should have developed, but due to the effect of a strong rock anisotropy, in each period one assemblage of fractures chiefly developed. Thus, two assemblages of fractures are usually developed in every part at present.

  8. Investigation of the porosity of rocks

    International Nuclear Information System (INIS)

    Methods for characterizing the nature of rock porosity in conjunction with diffusion experiments, are amongst the primary tools used in repository-site selection investigations. At this time no experimental method, alone, is capable of giving an unambiguous picture of the narrow-aperture pore space in crystalline rock. Methods giving information on overall properties must be complemented by those having high spatial resolution; then the lateral distribution of porosity within the matrix and its association with particular mineral phases or features, such as microfissures, fissure fillings, weathered or altered mineral phases etc, and the identification of diffusion pathways in inhomogeneous rock matrices can be determined. Nonsorbing, nonelectrolytic tracers should be used when one wants to determine rock-typical properties of the internal porosity without interference of interactions with surfaces. Preliminary information on a new method fulfilling these criteria is given. Impregnating rock samples with methylmethacrylate labeled with carbon-14 which, after impregnation, was polymerized by gamma radiation, gave specimens that made preparation of sections suitable for quantification by autoradiographic methods easy. Diffusion experiments can be conducted so that labeled MMA diffuses out of rock specimens into inactive free, MMA. Additional information may be gained by leaching PMMA fractions of lower molecular weight from the matrix

  9. Kinematics analysis of a robotic rock grinder

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    With the aim to discover water, life and resources in other planets, robotic sampling instrument is a crucial part of the space exploration robot. To remove dusty and weathered surfaces and expose the fresh rock underneath the planetary surface, a robotic rock grinder is considered to replace the geologist's rock hammer to carry out the geological investigation. A primary prototype of the robotic rock grinder with three degrees of freedom has been developed in this paper. Planetary transmission system is used in the grinding driving system with two inputs (rotation motor and revolution motor) and two outputs (grinding wheel and cutting brush). The grinding wheel with two teeth has been used to abrade the rock. The cutting brush is used to sweep the debris. The third actuator is to feed the grinding system. Kinematics of the grinding system has been analyzed. To get a continuous and smooth fresh face over the rock, grinding trajectory of the grinding wheel has been discussed and planned. Lastly, abrasion experiments have been made to testify the feasibility and the basic function of this system.

  10. Comparative study of static and dynamic parameters of rock for the Xishan Rock Cliff Statue

    Institute of Scientific and Technical Information of China (English)

    Jin JIANG; Jin-zhong SUN

    2011-01-01

    Ultrasonic wave testing was applied to investigate the quality and weathering status of rock specimens obtained in two borings situated in the Xishan Buddha rock slope in Taiyuan,China.This paper pays special attention to the distribution of bulk density,dynamic parameters and static parameters of rock specimens as well as the relationship between static and dynamic parameters.The results illustrate that the distribution of both parameters is identical along the depth of two drilled holes in the rock slope.When the hole depth increases,the density of rock mass,saturated compression strength and static elastic modulus,dynamic elastic modulus and wave velocity also show increase tendency.The weathering degree in the rock mass ranging from the surface of cliffto the depth of 2.5 m is the highest while the rock mass is unsalted and more rigid when the depth is larger than 3.0 m.The relationship between dynamic elastic modulus,sonic wave velocity and horizontal depth indicates that dynamic elastic modulus is more sensitive than sonic wave velocity.Conversely,by comparing quantity relationship between static elastic modulus and sonic wave velocity,it is found that the composition of rock has a great influence on the relationship between static and dynamic parameters,that is,inequality of rock composition will lead to dispersion and abnormality of the distribution of static and dynamic parameters.

  11. Mechanism of zonal disintegration in surrounding rock mass around deep rock engineering and its application

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    The mechanical behaviors of deep rock mass are different from those of shallow rock mass.Through cases of Jinping II Hydropower Station,the special phenomenon of zonal disintegration in the surrounding rock mass around the diversion tunnels,is analyzed.On the basis of fracture mechanics,a new strength criterion for deep rock mass is derived.The new nonlinear strength criterion that is relative to the rock mass rating classification can be applied to the study of the tensile failure of deep rock mass.Subsequently,zonal disintegration model is established,and the radius of fractured zone and none-fractured zone of deep surrounding rock mass around cylindrical tunnel are obtained,their exact positions and the evolution law of zonal disintegration of surrounding rock mass is determined.To validate the present model,comparison between calculation results and the experiment observation on facture and failure around underground openings is carried out.It is found that the numerical simulation result is in good agreement with the experimental one on failure modes around the hole.Through sensitivity analysis,the effects of stress condition,cohesion and the angle of internal friction on the phenomenon of zonal disintegration are determined.Finally,the present model is adopted in the analysis of the zonal disintegration in the surrounding rock mass around the diversion tunnels in Jinping II Hydropower Station.Meanwhile,the magnitude and distributions of fractured zones are determined by numerical simulation.

  12. Quantification of rock fall processes on recently deglaciated rock slopes, Gepatsch glacier, Tyrol (Austria)

    Science.gov (United States)

    Vehling, Lucas; Rohn, Joachim; Moser, Michael

    2014-05-01

    The recently deglaciated area in alpine glacier forefields is characterized by intensified mass movement processes in particular debris flows, shallow landslides and rockfalls. Due to enhanced geomorphic activity, rock slopes adjacent to shrinking glaciers contribute in a substantial way to the sediment budget. In this study, direct measurements of rock fall intensity are conducted by rock fall collector nets and natural sediment traps. The study area is a high mountain (1750-3520m a.s.l) catchment, which is recently about 30% glaciated. The extension of the Gepatsch glacier has been reducing since the little ice age maximum in the mid of the 19th century with an average annual shrinking rate of a few decameters at its tongue. The first results of the direct measurements demonstrate that on the recently deglaciated rock slopes, rock fall intensity is at least one order of magnitude higher (2,38-6,64 g/m2/d - corresponding backweathering rate: 0,3-0,9 mm/a) than on rock slopes which had has ice free since the last Pleistocene deglaciation (0,04-0,38 g/m2/d - backweathering rate: 0,005-0,05 mm/a). The highest rock fall intensity is attributed to the recent deglaciated rock slopes which are located close to larger fault systems (>60 g/m2/d - backweathering rate: >8 mm/a). Rock fall intensity shows also considerable intra-annual variations which are related to cold climate weathering processes and rainstorm activity.

  13. Deleted in liver cancer 1 (DLC1 negatively regulates Rho/ROCK/MLC pathway in hepatocellular carcinoma.

    Directory of Open Access Journals (Sweden)

    Carmen Chak-Lui Wong

    Full Text Available AIMS: Deleted in liver cancer 1 (DLC1, a member of RhoGTPase activating protein (GAP family, is known to have suppressive activities in tumorigenicity and cancer metastasis. However, the underlying molecular mechanisms of how DLC1 suppresses cell motility have not been fully elucidated. Rho-kinase (ROCK is an immediate down-stream effector of RhoA in mediating cellular cytoskeletal events and cell motility. In the present study, we aimed to investigate the effects of DLC1 on Rho/ROCK signaling pathway in hepatocellular carcinoma (HCC. METHODOLOGY/PRINCIPAL FINDINGS: We demonstrated that DLC1 negatively regulated ROCK-dependent actomyosin contractility. From immunofluorescence study, we found that ectopic expression of DLC1 abrogated Rho/ROCK-mediated cytoskeletal reorganization including formation of stress fibers and focal adhesions. It also downregulated cortical phosphorylation of myosin light chain 2 (MLC2. These inhibitory events by DLC1 were RhoGAP-dependent, as RhoGAP-deficient mutant of DLC1 (DLC1 K714E abolished these inhibitory events. In addition, from western study, DLC1 inhibited ROCK-related myosin light chain phosphatase targeting unit 1 (MYPT1 phosphorylation at Threonine 853. By examining cell morphology under microscope, we found that ectopic expression of dominant-active ROCK released cells from DLC1-induced cytoskeletal collapse and cell shrinkage. CONCLUSION: Our data suggest that DLC1 negatively regulates Rho/ROCK/MLC2. This implicates a ROCK-mediated pathway of DLC1 in suppressing metastasis of HCC cells and enriches our understanding in the molecular mechanisms involved in the progression of hepatocellular carcinoma.

  14. Caspase-3 dependent nitrergic neuronal apoptosis following cavernous nerve injury is mediated via RhoA and ROCK activation in major pelvic ganglion.

    Science.gov (United States)

    Hannan, Johanna L; Matsui, Hotaka; Sopko, Nikolai A; Liu, Xiaopu; Weyne, Emmanuel; Albersen, Maarten; Watson, Joseph W; Hoke, Ahmet; Burnett, Arthur L; Bivalacqua, Trinity J

    2016-01-01

    Axonal injury due to prostatectomy leads to Wallerian degeneration of the cavernous nerve (CN) and erectile dysfunction (ED). Return of potency is dependent on axonal regeneration and reinnervation of the penis. Following CN injury (CNI), RhoA and Rho-associated protein kinase (ROCK) increase in penile endothelial and smooth muscle cells. Previous studies indicate that nerve regeneration is hampered by activation of RhoA/ROCK pathway. We evaluated the role of RhoA/ROCK pathway in CN regulation following CNI using a validated rat model. CNI upregulated gene and protein expression of RhoA/ROCK and caspase-3 mediated apoptosis in the major pelvic ganglion (MPG). ROCK inhibitor (ROCK-I) prevented upregulation of RhoA/ROCK pathway as well as activation of caspase-3 in the MPG. Following CNI, there was decrease in the dimer to monomer ratio of neuronal nitric oxide synthase (nNOS) protein and lowered NOS activity in the MPG, which were prevented by ROCK-I. CNI lowered intracavernous pressure and impaired non-adrenergic non-cholinergic-mediated relaxation in the penis, consistent with ED. ROCK-I maintained the intracavernous pressure and non-adrenergic non-cholinergic-mediated relaxation in the penis following CNI. These results suggest that activation of RhoA/ROCK pathway mediates caspase-3 dependent apoptosis of nitrergic neurons in the MPG following CNI and that ROCK-I can prevent post-prostatectomy ED. PMID:27388816

  15. Gusev Rocks Solidified from Lava (False Color)

    Science.gov (United States)

    2006-01-01

    In recent weeks, as NASA's Mars Exploration Rover Spirit has driven through the basin south of 'Husband Hill,' it has been traversing mainly sand and dune deposits. This week, though, Spirit has been maneuvering along the edge of an arc-shaped feature called 'Lorre Ridge' and has encountered some spectacular examples of basaltic rocks with striking textures. This panoramic camera (Pancam) image shows a group of boulders informally named 'FuYi.' These basaltic rocks were formed by volcanic processes and may be a primary constituent of Lorre Ridge and other interesting landforms in the basin. Spirit first encountered basalts at its landing site two years ago, on a vast plain covered with solidified lava that appeared to have flowed across Gusev Crater. Later, basaltic rocks became rare as Spirit climbed Husband Hill. The basaltic rocks that Spirit is now seeing are interesting because they exhibit many small holes or vesicles, similar to some kinds of volcanic rocks on Earth. Vesicular rocks form when gas bubbles are trapped in lava flows and the rock solidifies around the bubbles. When the gas escapes, it leaves holes in the rock. The quantity of gas bubbles in rocks on Husband Hill varies considerably; some rocks have none and some, such as several here at FuYi, are downright frothy. The change in textures and the location of the basalts may be signs that Spirit is driving along the edge of a lava flow. This lava may be the same as the basalt blanketing the plains of Spirit's landing site, or it may be different. The large size and frothy nature of the boulders around Lorre Ridge might indicate that eruptions once took place at the edge of the lava flow, where the lava interacted with the rocks of the basin floor. Scientists hope to learn more as Spirit continues to investigate these rocks. As Earth approaches the Chinese New Year (The Year of the Dog), the Athena science team decided to use nicknames representing Chinese culture and geography to identify rocks and

  16. Gusev Rocks Solidified from Lava (3-D)

    Science.gov (United States)

    2006-01-01

    In recent weeks, as NASA's Mars Exploration Rover Spirit has driven through the basin south of 'Husband Hill,' it has been traversing mainly sand and dune deposits. This week, though, Spirit has been maneuvering along the edge of an arc-shaped feature called 'Lorre Ridge' and has encountered some spectacular examples of basaltic rocks with striking textures. This panoramic camera (Pancam) image shows a group of boulders informally named 'FuYi.' These basaltic rocks were formed by volcanic processes and may be a primary constituent of Lorre Ridge and other interesting landforms in the basin. Spirit first encountered basalts at its landing site two years ago, on a vast plain covered with solidified lava that appeared to have flowed across Gusev Crater. Later, basaltic rocks became rare as Spirit climbed Husband Hill. The basaltic rocks that Spirit is now seeing are interesting because they exhibit many small holes or vesicles, similar to some kinds of volcanic rocks on Earth. Vesicular rocks form when gas bubbles are trapped in lava flows and the rock solidifies around the bubbles. When the gas escapes, it leaves holes in the rock. The quantity of gas bubbles in rocks on Husband Hill varies considerably; some rocks have none and some, such as several here at FuYi, are downright frothy. The change in textures and the location of the basalts may be signs that Spirit is driving along the edge of a lava flow. This lava may be the same as the basalt blanketing the plains of Spirit's landing site, or it may be different. The large size and frothy nature of the boulders around Lorre Ridge might indicate that eruptions once took place at the edge of the lava flow, where the lava interacted with the rocks of the basin floor. Scientists hope to learn more as Spirit continues to investigate these rocks. As Earth approaches the Chinese New Year (The Year of the Dog), the Athena science team decided to use nicknames representing Chinese culture and geography to identify rocks and

  17. New Rock Physical Properties Assessments From the Mars Exploration Rover Rock Abrasion Tool (RAT).

    Science.gov (United States)

    Bartlett, P. W.; Basso, B.; Kusack, A.; Wilson, J.; Zacny, K.

    2005-12-01

    The Rock Abrasion Tool (RAT) serves as the sample preparation device on the Mars Exploration Rovers (MER) science payload. The RAT grinds a circular area 45 millimeter in diameter, and on the order of a few millimeters deep, into a rock face. This process removes surface fines and weathered layers in preparation for imaging and spectral observations of the rock. As of September 2005, 15 grinding operations have been performed at Gusev Crater and 26 at Meridiani Planum. Since the RAT performs a mechanical operation on a rock, deductions can be made via the RAT's engineering data about the rock's physical properties. For each grinding operation, the energy consumed while grinding is converted to provide a physically relevant Specific Grind Energy (SGE) in terms of Joules per cubic millimeter of rock removed. The calculation is performed over the last 0.25 millimeter of a grinding operation, where it is possible, by taking measurements from Microscopic Imager images of the abraded area, to make an accurate estimate of the volume of rock removed. Progress is presented on recent refinement of the SGE calculation methods including decoupling of artifacts. Environmental factors and differing parameters used to command the RAT operations are among the key artifacts recently analyzed. Progress is also presented on further characterization of the dynamics and wear mechanics involved in the grinding process, and how they influence SGE. A library of Earth rocks has been assembled and it is being used with the RAT Engineering Model to create a set of similar SGE data products that can be compared to Mars rocks in order to contribute to physical properties assessments of the Mars rocks. Initial results indicate that the Martian rocks are analogous to a range of Earth rocks, from gypsum to low-strength basalt in terms of grindability; however, caution needs to be exercised in making a direct comparison of grinding energies. This is because the grindability of rocks was found to

  18. Performance Assessment of Hard Rock TBM and Rock Boreability Using Punch Penetration Test

    Science.gov (United States)

    Jeong, Ho-Young; Cho, Jung-Woo; Jeon, Seokwon; Rostami, Jamal

    2016-04-01

    Rock indentation tests are often called punch penetration tests and are known to be related to penetration rates of drilling equipment and hard rock tunnel boring machines (TBMs). Various indices determined from analysis of the force-penetration plot generated from indentation tests have been used to represent the drillability, boreability, and brittleness of rocks. However, no standard for the punch penetration test procedure or method for calculating the related indices has been suggested or adopted in the rock mechanics community. This paper introduces new indices based on the punch test to predict the performance of hard rock TBMs. A series of punch tests was performed on rock specimens representing six rock formations in Korea with different dimensions, i.e., the core specimens had different lengths and diameters. Of the indices obtained from the punch tests, the peak load index and mean load index showed good correlations with the cutting forces measured in full-scale linear cutting machine tests on the same rock types. The indices also showed good linear correlations with the ratio of uniaxial strength to Brazilian tensile strength, which indicates the brittleness of rock. The scale effect of using core specimens was investigated, and a preferred dimension for the punch test specimens is proposed. This paper also discusses the results of the punch test and full-scale rock cutting tests using LCM. The results of this study confirm that the proposed indices from the punch tests can be used to provide a reliable prediction of the cutting forces that act on a disc cutter. The estimated cutting forces can then be used for optimization of cutter-head design and performance prediction of hard rock TBMs.

  19. Rockburst Generation in Discontinuous Rock Masses

    Science.gov (United States)

    He, Ben-Guo; Zelig, Ravit; Hatzor, Yossef H.; Feng, Xia-Ting

    2016-10-01

    We study rockburst generation in discontinuous rock masses using theoretical and numerical approaches. We begin by developing an analytical solution for the energy change due to tunneling in a continuous rock mass using linear elasticity. We show that the affected zone where most of the increase in elastic strain energy takes place is restricted to an annulus that extends to a distance of three diameters from the tunnel center, regardless of initial tunnel diameter, magnitude of in situ stress, and in situ stress ratio. By considering local elastic strain concentrations, we further delineate the Rockbursting Prone Zone found to be concentrated in an annulus that extends to one diameter from the tunnel center, regardless of original stress ratio, magnitude, and the stiffness of the rock mass. We proceed by arguing that in initially discontinuous rock masses shear stress amplification due to tunneling will inevitably trigger block displacements along preexisting discontinuities much before shear failure of intact rock elements will ensue, because of the lower shear strength of discontinuities with respect to intact rock elements, provided of course that the blocks are removable. We employ the numerical discrete element DDA method to obtain, quantitatively, the kinetic energy, the elastic strain energy, and the dissipated energy in the affected zone in a discontinuous rock due to tunneling. We show that the kinetic energy of ejected blocks due to strain relaxation increases with increasing initial stress and with decreasing frictional resistance of preexisting discontinuities. Finally, we demonstrate how controlled strain energy release by means of top heading and bench excavation methodology can assist in mitigating rockburst hazards due to stain relaxation.

  20. Cecal bacterial communities in wild Japanese rock ptarmigans and captive Svalbard rock ptarmigans.

    Science.gov (United States)

    Ushida, Kazunari; Segawa, Takahiro; Tsuchida, Sayaka; Murata, Koichi

    2016-02-01

    Preservation of indigenous gastrointestinal microbiota is deemed to be critical for successful captive breeding of endangered wild animals, yet its biology is poorly understood. Here, we investigated cecal bacterial communities in wild Japanese rock ptarmigans (Lagopus muta japonica) and compared them with those in Svalbard rock ptarmigans (L. m. hyperborea) in captivity. Ultra-deep sequencing of 16S rRNA gene indicated that the community structure of cecal microbiota in wild rock ptarmigans was remarkably different from that in captive Svalbard rock ptarmigans. Fundamental differences between bacterial communities in the two groups of birds were detected at the phylum level. Firmicutes, Actinobacteria, Bacteroidetes and Synergistetes were the major phyla detected in wild Japanese rock ptarmigans, whereas Firmicutes alone occupied more than 80% of abundance in captive Svalbard rock ptarmigans. Furthermore, unclassified genera of Coriobacteriaceae, Synergistaceae, Bacteroidaceae, Actinomycetaceae, Veillonellaceae and Clostridiales were the major taxa detected in wild individuals, whereas in zoo-reared birds, major genera were Ruminococcus, Blautia, Faecalibacterium and Akkermansia. Zoo-reared birds seemed to lack almost all rock ptarmigan-specific bacteria in their intestine, which may explain the relatively high rate of pathogenic infections affecting them. We show evidence that preservation and reconstitution of indigenous cecal microflora are critical for successful ex situ conservation and future re-introduction plan for the Japanese rock ptarmigan. PMID:26468217

  1. Heterogeneity of Parent Rocks and Its Constraints on Geochemical Criteria in Weathering Crusts of Carbonate Rocks

    Institute of Scientific and Technical Information of China (English)

    WANG Shijie; FENG Zhigang

    2004-01-01

    Owing to the low contents of their acid-insoluble components, carbonate rocks tend to decrease sharply in volume in association with the formation of weathering crust. The formation of a 1 m-thick weathering crust would usually consume more than ten meters to several tens of meters of thickness of parent rocks. The knowledge of how to identify the homogeneity of parent rocks is essential to understand the formation mechanism of weathering crust in karst regions,especially that of thick-layered red weathering crust. In this work the grain-size analyses have demonstrated that the three profiles studied are the residual weathering crust of carbonate rocks and further showed that there objectively exists the heterogeneity of parent rocks in the three studied weathering crusts. The heterogeneity of parent rocks can also be reflected in geochemical parameters of major elements, just as the characteristics of frequency plot of grain-size distribution.Conservative trace element ratios Zr/Hf and Nb/Ta are proven to be unsuitable for tracing the heterogeneity of parent rocks of weathering crust, but its geochemical mechanism is unclear. The authors strongly suggest in this paper that the identification of the homogeneity of parent rocks of weathering crust in karst regions is of prime necessity.

  2. THM-coupled modeling of selected processes in argillaceous rock relevant to rock mechanics

    International Nuclear Information System (INIS)

    Scientific investigations in European countries other than Germany concentrate not only on granite formations (Switzerland, Sweden) but also on argillaceous rock formations (France, Switzerland, Belgium) to assess their suitability as host and barrier rock for the final storage of radioactive waste. In Germany, rock salt has been under thorough study as a host rock over the past few decades. According to a study by the German Federal Institute for Geosciences and Natural Resources, however, not only salt deposits but also argillaceous rock deposits are available at relevant depths and of extensions in space which make final storage of high-level radioactive waste basically possible in Germany. Equally qualified findings about the suitability/unsuitability of non-saline rock formations require fundamental studies to be conducted nationally because of the comparatively low level of knowledge. The article presents basic analyses of coupled mechanical and hydraulic properties of argillaceous rock formations as host rock for a repository. The interaction of various processes is explained on the basis of knowledge derived from laboratory studies, and open problems are deduced. For modeling coupled processes, a simplified analytical computation method is proposed and compared with the results of numerical simulations, and the limits to its application are outlined. (orig.)

  3. Perception of the Hard Rock Brand by Czech University Students

    OpenAIRE

    Polák, Ivan

    2010-01-01

    The goal of this thesis is to understand perception of the Hard Rock brand in the Czech Republic among university students. Hard Rock Cafe Prague is a combination of a restaurant, bar, and rock club operated by the hospitality corporation Hard Rock International. The studied segment can be seen as a group of potential customers in long term, and this research should identify opportunities for growth of Czech guests. The thesis presents the process and results of Hard Rock brand research on th...

  4. Experimental Study on the Fractal Characteristics of Rocks Crushing

    OpenAIRE

    Cai Gaipin; Xiong Yang; Lin Longfei

    2015-01-01

    A fractal model for the size distribution was proposed based on the fractal character of the crushing granularity of rocks. The crushing tests of three different rocks were conducted. And the test results of rock size distribution were used to conduct a statistical analysis. The results indicate that the fractal characteristics of rock are universal. The fractal dimension is one of perfect indicators to evaluate crushing, reflecting the whole process of the rock crushing. Subsequently, the re...

  5. Theoretical Modeling of Rock Breakage by Hydraulic and Mechanical Tool

    OpenAIRE

    Hongxiang Jiang; Changlong Du; Songyong Liu; Liping Wang

    2014-01-01

    Rock breakage by coupled mechanical and hydraulic action has been developed over the past several decades, but theoretical study on rock fragmentation by mechanical tool with water pressure assistance was still lacking. The theoretical model of rock breakage by mechanical tool was developed based on the rock fracture mechanics and the solution of Boussinesq’s problem, and it could explain the process of rock fragmentation as well as predicating the peak reacting force. The theoretical model o...

  6. Resources of Kaolinite Rocks in China Coal Measures

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    The proved reserve of kaolinite rocks in China coal measures is about 1. 673 billion tons. The types of kaolinite rocks contain tonstein, flintclay and soft kaolin. Their origin modes include alteration of volcanic ash, terrigenous clay deposit and weathering of coal and adjacent rocks. The organic matter and organic acid play an important role in the formation of kaolinite rocks of coal measures. The difference in properties between kaolinite rock and traditional kaolin requires different processing technologies.

  7. Phosphate rock costs, prices and resources interaction.

    Science.gov (United States)

    Mew, M C

    2016-01-15

    This article gives the author's views and opinions as someone who has spent his working life analyzing the international phosphate sector as an independent consultant. His career spanned two price hike events in the mid-1970's and in 2008, both of which sparked considerable popular and academic interest concerning adequacy of phosphate rock resources, the impact of rising mining costs and the ability of mankind to feed future populations. An analysis of phosphate rock production costs derived from two major industry studies performed in 1983 and 2013 shows that in nominal terms, global average cash production costs increased by 27% to $38 per tonne fob mine in the 30 year period. In real terms, the global average cost of production has fallen. Despite the lack of upward pressure from increasing costs, phosphate rock market prices have shown two major spikes in the 30 years to 2013, with periods of less volatility in between. These price spike events can be seen to be related to the escalating investment cost required by new mine capacity, and as such can be expected to be repeated in future. As such, phosphate rock price volatility is likely to have more impact on food prices than rising phosphate rock production costs. However, as mining costs rise, recycling of P will also become increasingly driven by economics rather than legislation. PMID:26412420

  8. Hand Injury in Rock Climbing: Literature Review.

    Science.gov (United States)

    Pozzi, A; Pivato, G; Pegoli, L

    2016-02-01

    With the amazing increasing in number of participants, rock climbing has become a popular sport in the last decade. A growing number of participants, with different skill level, inevitably leads to an increased number of injuries related to this practice. The kind of lesions that can be observed in rock-climbers is very specific and often involves the hand. For this reason is very important for any hand surgeon that is exposed to sport injuries to know which and the most common injuries related to this sport and which are the basic principles for the treatment of those. The aim of this article is to review the literature that has been published in the last ten year in this topic. On the NCBI database 22 articles where found that where related to rock climbing lesion affecting the hand or the whole body. Differences where found according to kind of rock climbing activity that was analyzed, alpine climb leads to more serious injuries, often affecting the lower limb, while in sport and recreational rock climbing the upper limb and the hand are definitely the most affected parts. Flexor pulley lesions, followed by fractures and strains are the most common lesions affecting the hand that are related to this practice. PMID:27454496

  9. Automated sliding susceptibility mapping of rock slopes

    Directory of Open Access Journals (Sweden)

    A. Günther

    2004-01-01

    Full Text Available We present a suite of extensions for ARCVIEW GIS™ (ESRI that allows to map the spatial distribution of first-order mechanical slope-properties in hard rock terrain, e.g. for large slope areas like water reservoir slopes. Besides digital elevation data, this expert-system includes regional continuous grid-based data on geological structures that might act as potential sliding or cutoff planes for rockslides. The system allows rapid automated mapping of geometrical and kinematical slope properties in hard rock, providing the basis for spatially distributed deterministic sliding-susceptibility evaluations on a pixel base. Changing hydrostatic slope conditions and rock mechanical parameters can be implemented and used for simple predictive static stability calculations. Application is demonstrated for a study area in the Harz Mts., Germany.

  10. Siliceous microfossil extraction from altered Monterey rocks

    Energy Technology Data Exchange (ETDEWEB)

    Nelson, C.O.; Casey, R.E.

    1986-04-01

    Samples of altered Monterey rocks of differing lithologies were processed by various methods to develop new techniques for extracting siliceous microfossils. The preliminary use of thin sections made from the same rocks reduced the number of probable samples (samples worth further processing) by about one-third. Most of the siliceous microfossils contained in altered Monterey rocks appear to be highly recrystallized and are extremely fragile; however, some contained silicified and silica-infilled radiolarians and planktonic and benthonic foraminifera, which are very tough. In general the most useful techniques were gently hydrochloric acid, hydrogen peroxide, formic acid, monosodium glutamate, and regular siliceous microfossil extraction techniques. Unsuccessful techniques and a new siliceous microfossil flotation technique are also documented.

  11. Generalized Models for Rock Joint Surface Shapes

    Directory of Open Access Journals (Sweden)

    Shigui Du

    2014-01-01

    Full Text Available Generalized models of joint surface shapes are the foundation for mechanism studies on the mechanical effects of rock joint surface shapes. Based on extensive field investigations of rock joint surface shapes, generalized models for three level shapes named macroscopic outline, surface undulating shape, and microcosmic roughness were established through statistical analyses of 20,078 rock joint surface profiles. The relative amplitude of profile curves was used as a borderline for the division of different level shapes. The study results show that the macroscopic outline has three basic features such as planar, arc-shaped, and stepped; the surface undulating shape has three basic features such as planar, undulating, and stepped; and the microcosmic roughness has two basic features such as smooth and rough.

  12. NEW THEORY IN TUNNEL STABLILITY CONTROL OF SOFT ROCK ——MECHANICS OF SOFT ROCK ENGINEERING

    Institute of Scientific and Technical Information of China (English)

    何满朝

    1996-01-01

    Tunnel stability control is a world-wide difficult problem. For the sake of solving it,the new theory of soft rock engineering mechanics has been estabilished. Some key points,such as the definition and classification of soft rock, mechanical deformation mechanism of a soft rock tunnel, the critical support technique of soft rock tunnel and the new theory of the soft rock tunnel stability control are proposed in this paper.

  13. The Marocche rock avalanches (Trentino, Italy)

    Science.gov (United States)

    Ivy-Ochs, Susan; Martin, Silvana; Campedel, Paolo; Viganò, Alfio; Alberti, Silvio; Rigo, Manuel; Vockenhuber, Christof

    2015-04-01

    The floors of the Adige and Sarca River valleys are punctuated by numerous rock avalanche deposits of undetermined age. With a view to understanding predisposition and triggering factors, thus ultimately paleoseismicity in the region, we are studying the geomorphology and timing of the largest rock avalanches of the River Sarca-Lake Garda area (e.g., Marocche, Monte Spinale, Lago di Tovel, Lago di Molveno, San Giovanni and Torbole). Among the most extensive of these deposits, with an area of 13 km2 and a volume of about 109 m3, are the Marocche. Marocche deposits cover the lower Sarca valley north of Lake Garda for a length of more than 8 km with 200 m of debris. Both collapse and bedding parallel sliding are a consequence of dip slopes and the extreme relief on the right side of the valley of nearly 2000 m from the bedrock below the valley floor to the peaks combined with the zones of structural weakness. The rock avalanches developed within carbonate rocks of Mesozoic age, mainly limestones of the Jurassic Calcari Grigi Group. The main scarps are located on the western side of the lower Sarca Valley, along the steep faces of Mt. Brento and Mt. Casale. The presence of these scarps is strictly related to the Southern Giudicarie and the Ballino fault systems. The former is here constituted by regular NNE-directed ESE-vergent thrust faults. The latter has been reactivated as normal faults. These complicated structural relationships favored complex failure mechanisms, including rock slide and massive collapse. At the Marocche itself, based on field relationships and analysis of lidar imagery, we differentiated two large rock avalanches: the Marocca di Kas in the south which overlies and in part buries the Marocche (s.s.) in the northern sector. Previous mapping had suggested up to five rock avalanches in the area where we differentiate two. In spite of hypotheses suggesting failure of the rock avalanches onto stagnating late Pleistocene glaciers, preliminary 36Cl

  14. Aespoe Hard Rock Laboratory Annual Report 1999

    International Nuclear Information System (INIS)

    The Aespoe Hard Rock Laboratory has been constructed as part of the preparations for the deep geological repository for spent nuclear fuel in Sweden. The Tracer Retention Understanding Experiments are made to gain a better understanding of radionuclide retention in the rock and create confidence in the radionuclide transport models that are intended to be used in the licensing of a deep repository for spent fuel. The TRUE -1 experiment including tests with sorbing radioactive tracers in a single fracture over a distance of about 5 m has been completed. Diffusion and sorption in the rock matrix is the dominant retention mechanism over the time scales of the experiments. The main objective of the TRUE Block Scale Experiment is to increase understanding and our ability to predict tracer transport in a fracture network over spatial scales of 10 to 50 m. In total six boreholes have been drilled into the experimental volume located at the 450 m level. The Long-Term Diffusion Experiment is intended as a complement to the dynamic in-situ experiments and the laboratory experiments performed in the TRUE Programme. Diffusion from a fracture into the rock matrix will be studied in situ. The REX project focuses on the reduction of oxygen in a repository after closure due to reactions with rock minerals and microbial activity. Results show that oxygen is consumed within a few days both for the field and laboratory experiments. A new site for the CHEMLAB experiments was selected and prepared during 1999. All future experiment will be conducted in the J niche at 450 m depth. The Prototype Repository Test is focused on testing and demonstrating repository system function. A full-scale prototype including six deposition holes with canisters with electric heaters surrounded by highly compacted bentonite will be built and instrumented. Characterisation of the rock mass in the area of the Prototype repository is completed and the six deposition holes have been drilled. The Backfill and

  15. Radiometric dating of rocks. Chapter 18

    International Nuclear Information System (INIS)

    The study of the abundances and variations in the isotopes of several elements both stable and unstable has become an indispensable approach in earth sciences that helps in understanding the problems related to the age of the rocks and minerals, petrogenesis of a suite of rocks, provenance studies and others. In this article, some commonly used dating methods have been discussed with emphasis on their applications, experimental techniques and instrumentation. Zircon chronology which has now developed as a specialized branch of geochronology is discussed

  16. First look at rock & soil properties

    Science.gov (United States)

    1997-01-01

    The earliest survey of spectral properties of the rocks and soils surrounding Pathfinder was acquired as a narrow strip covering the region just beyond the where the rover made its egress from the lander. The wavelength filters used, all in the binocular camera's right eye, cover mainly visible wavelengths. These data reveal at least five kinds of rocks and soil in the immediate vicinity of the lander. All of the spectra are ratioed to the mean spectrum of bright red drift to highlight the differences. Different occurrences of drift (pink spectra) are closely similar. Most of the rocks (black spectra) have a dark gray color, and are both darker and less red than the drift, suggesting less weathering. Typical soils (green spectra) are intermediate in properties to the rocks and drift. Both these data and subsequent higher resolution images show that the typical soil consists of a mixture of drift and small dark gray particles resembling the rock. However, two other kinds of materials are significantly different from the rocks and drift. Pinkish or whitish pebbles and crusts on some of the rocks (blue spectra) are brighter in blue light and darker in near-infrared light than is the drift, and they lack the spectral characteristics closely associated with iron minerals. Dark red soils in the lee of several rocks are about as red as the drift, but consistently darker. The curvature in the spectrum at visible wavelengths suggests either more ferric iron minerals than in the drift or a larger particle size.Mars Pathfinder is the second in NASA's Discovery program of low-cost spacecraft with highly focused science goals. The Jet Propulsion Laboratory, Pasadena, CA, developed and manages the Mars Pathfinder mission for NASA's Office of Space Science, Washington, D.C. The Imager for Mars Pathfinder (IMP) was developed by the University of Arizona Lunar and Planetary Laboratory under contract to JPL. Peter Smith is the Principal Investigator. JPL is an operating division of

  17. Correlation between roughness and porosity in rocks

    Science.gov (United States)

    Rebollo, M. A.; Hogert, E. N.; Albano, J.; Raffo, C. A.; Gaggioli, N. G.

    1996-02-01

    The porosity of rocks is a very important parameter in the determination of the performance of oil wells. Optical methods allow us to study surface roughness and different materials that have surface properties with random characteristics. Therefore, we have extended these applications to porosity analysis. In our method, we have used the speckle produced by the scattered light from a porous rock, illuminated by a laser beam, and found a linear relationship between the decorrelation of the speckle intensity distribution and the porosity magnitude. In this paper we present the results for samples extracted from oil wells in Argentina.

  18. Aespoe Hard Rock Laboratory Annual Report 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-08-01

    The Aespoe Hard Rock Laboratory has been constructed as part of the preparations for the deep geological repository for spent nuclear fuel in Sweden. The Tracer Retention Understanding Experiments are made to gain a better understanding of radionuclide retention in the rock and create confidence in the radionuclide transport models that are intended to be used in the licensing of a deep repository for spent fuel. The TRUE -1 experiment including tests with sorbing radioactive tracers in a single fracture over a distance of about 5 m has been completed. Diffusion and sorption in the rock matrix is the dominant retention mechanism over the time scales of the experiments. The main objective of the TRUE Block Scale Experiment is to increase understanding and our ability to predict tracer transport in a fracture network over spatial scales of 10 to 50 m. In total six boreholes have been drilled into the experimental volume located at the 450 m level. The Long-Term Diffusion Experiment is intended as a complement to the dynamic in-situ experiments and the laboratory experiments performed in the TRUE Programme. Diffusion from a fracture into the rock matrix will be studied in situ. The REX project focuses on the reduction of oxygen in a repository after closure due to reactions with rock minerals and microbial activity. Results show that oxygen is consumed within a few days both for the field and laboratory experiments. A new site for the CHEMLAB experiments was selected and prepared during 1999. All future experiment will be conducted in the J niche at 450 m depth. The Prototype Repository Test is focused on testing and demonstrating repository system function. A full-scale prototype including six deposition holes with canisters with electric heaters surrounded by highly compacted bentonite will be built and instrumented. Characterisation of the rock mass in the area of the Prototype repository is completed and the six deposition holes have been drilled. The Backfill and

  19. Determination of chlorine in silicate rocks

    Science.gov (United States)

    Peck, L.C.

    1959-01-01

    In a rapid accurate method for the determination of chlorine in silicate rocks, the rock powder is sintered with a sodium carbonate flux containing zinc oxide and magnesium carbonate. The sinter cake is leached with water, the resulting solution is filtered, and the filtrate is acidified with nitric acid. Chlorine is determined by titrating this solution with mercuric nitrate solution using sodium nitroprusside as the indicator. The titration is made in the dark with a beam of light shining through the solution. The end point of the titration is found by visually comparing the intensity of this beam of light with that of a similar beam of light in a reference solution.

  20. The thermal evolution indicator of carbonate rocks

    Institute of Scientific and Technical Information of China (English)

    王兆云; 范璞; 程克明

    1995-01-01

    It has been studied by the solid state 13C NMR analysis that the chemical composition and the structure feature of kerogen of carbonate rocks are characteristic of different types and evolution degree. The purpose is to show the evolution degree using the structure parameters of kerogen of carbonate rocks. The detailed analysis of the carbon aromaticity (fa), the hydrogen aromaticity (Ha) and the average aromatic cluster size (Xb) indicates that Xb is the most effective indicator of evolution degree, and it is not influenced by the type and evolution degree of kerogen. The correlation between the average aromatic cluster size and vitrinite reflectance value of kerogen has also been established.

  1. Rock et Cinéma

    OpenAIRE

    Bart, Christian Le; Didelot, Jérôme; Eizykman, Claudine; Gorin, François; Grünberg, Serge; Jousse, Thierry; Juiller, Laurent; Le Guern, Philippe; Leveratto, Jean-Marc; Neyrat, Cyril; ribac, françois; Siclier, Sylvain

    2006-01-01

    This special issue of Volume ! is dedicated to the relationships between rock music and cinema. It was published during the second edition of the Paris-Cinéma Festival. Its articles analyze the use of rock 'n' roll in various films: Phantom of Paradise by Brian De Palma, Exploding Plastic Inevitable by Andy Warhol with The Velvet Underground's music, A Hard Day's Night by Richard Lester, David Lynch movies, as well as Frank Zappa, Aphex Twin and "kinok". Ce hors-série de Volume ! est consa­c...

  2. Petrological studies of plutonic rocks of Ecuador

    International Nuclear Information System (INIS)

    The feldspars of many tonalitic plutonic rocks in the coastal regions and West Andean regions are zoned. This leads to the conclusion that they are relatively flat intrusions and to some extent transition rocks in the subvulcanite direction. This is in accordance with the genetic and chronological relationship between plutonites and the surrounding vulcanites of the Basic Igreous Complex (BIC). The composition of representative minerals, e.g. alkali feldspar, plagioclase feldspar, biotite, chlorite, and amphibole has been determined as well as the age of plutonite samples by the K/Ar dating method. (DG)

  3. Influence Mechanism of Grouting on Mechanical Characteristics of Rock Mass

    Directory of Open Access Journals (Sweden)

    Zhang Jixun

    2013-01-01

    Full Text Available Grouting technology has been widely used in all fields of geotechnical and civil engineering. Prospective engineering objectives including reinforcement of rock mass and groundwater leakage treatment can be achieved by grouting which will change the mechanical parameters of rock mass such as strength, elastic modulus, and coefficient of permeability. In this paper, rock mass is assumed as a composite material consisting of rock particles and random microcracks initially. Since part or all of the cracks will be filled with cement slurry after grouting, rock mass consists of rock particles, grout condensate, and some or no random microcracks after grouting. The damage constitutional law of the mesoscopic element is established based on the theory of mesoscopic damage mechanics. With the heterogeneity of the components of rock mass considered, the variation of mechanical characteristics of rock mass is studied before and after grouting. And the influence mechanism of grouting on rock mass is investigated at mesoscale level.

  4. Interim rock mass properties and conditions for analyses of a repository in crystalline rock

    International Nuclear Information System (INIS)

    A summary of rock properties for generic crystalline rock is compiled from literature sources to provide the input data for analyses of a conceptual repository in crystalline rock. Frequency histograms, mean values and ranges of physical, mechanical, thermal, and thermomechanical properties, and the dependence of these properties on temperature are described. A description of the hydrogeologic properties of a crystalline rock mass and their dependence on depth is provided. In addition, the temperature gradients, mean annual surface temperature, and in situ stress conditions are summarized for the three regions of the United States currently under consideration to host a crystalline repository; i.e., the North Central, Northeastern, and Southeastern. Brief descriptions of the regional geology are also presented. Large-scale underground experiments in crystalline rock at Stripa, Sweden, and in Climax Stock in Nevada, are reviewed to assess whether the rock properties presented in this report are representative of in situ conditions. The suitability of each rock property and the sufficiency of its data base are described. 110 refs., 27 figs., 4 tabs

  5. Theoretical study of rock mass investigation efficiency

    Energy Technology Data Exchange (ETDEWEB)

    Holmen, Johan G.; Outters, Nils [Golder Associates, Uppsala (Sweden)

    2002-05-01

    The study concerns a mathematical modelling of a fractured rock mass and its investigations by use of theoretical boreholes and rock surfaces, with the purpose of analysing the efficiency (precision) of such investigations and determine the amount of investigations necessary to obtain reliable estimations of the structural-geological parameters of the studied rock mass. The study is not about estimating suitable sample sizes to be used in site investigations.The purpose of the study is to analyse the amount of information necessary for deriving estimates of the geological parameters studied, within defined confidence intervals and confidence level In other words, how the confidence in models of the rock mass (considering a selected number of parameters) will change with amount of information collected form boreholes and surfaces. The study is limited to a selected number of geometrical structural-geological parameters: Fracture orientation: mean direction and dispersion (Fisher Kappa and SRI). Different measures of fracture density (P10, P21 and P32). Fracture trace-length and strike distributions as seen on horizontal windows. A numerical Discrete Fracture Network (DFN) was used for representation of a fractured rock mass. The DFN-model was primarily based on the properties of an actual fracture network investigated at the Aespoe Hard Rock Laboratory. The rock mass studied (DFN-model) contained three different fracture sets with different orientations and fracture densities. The rock unit studied was statistically homogeneous. The study includes a limited sensitivity analysis of the properties of the DFN-model. The study is a theoretical and computer-based comparison between samples of fracture properties of a theoretical rock unit and the known true properties of the same unit. The samples are derived from numerically generated boreholes and surfaces that intersect the DFN-network. Two different boreholes are analysed; a vertical borehole and a borehole that is

  6. A Negative Regulatory Mechanism Involving 14-3-3ζ Limits Signaling Downstream of ROCK to Regulate Tissue Stiffness in Epidermal Homeostasis

    DEFF Research Database (Denmark)

    Kular, Jasreen; Scheer, Kaitlin G; Pyne, Natasha T;

    2015-01-01

    ROCK signaling causes epidermal hyper-proliferation by increasing ECM production, elevating dermal stiffness, and enhancing Fak-mediated mechano-transduction signaling. Elevated dermal stiffness in turn causes ROCK activation, establishing mechano-reciprocity, a positive feedback loop that can...... promote tumors. We have identified a negative feedback mechanism that limits excessive ROCK signaling during wound healing and is lost in squamous cell carcinomas (SCCs). Signal flux through ROCK was selectively tuned down by increased levels of 14-3-3ζ, which interacted with Mypt1, a ROCK signaling...... antagonist. In 14-3-3ζ(-/-) mice, unrestrained ROCK signaling at wound margins elevated ECM production and reduced ECM remodeling, increasing dermal stiffness and causing rapid wound healing. Conversely, 14-3-3ζ deficiency enhanced cutaneous SCC size. Significantly, inhibiting 14-3-3ζ with a novel...

  7. The advance and development of damage measurement technique of rock

    Institute of Scientific and Technical Information of China (English)

    YANG Geng-she(杨更社)

    2003-01-01

    The key problem of rock damage mechanics is that determination of the variable of rock damage and the establishment of damage constitutive relation of rock, which is inevitable involved in the measurement problem of rock. In this paper, the measurement technology and method of rock damage are comprehensively narrated, analyzed and studied. On the basis of the narrating the former study, a new method (Computerized Tomography,CT for short) is introduced, which is applied to rock damage measurement. On the other hand, some newest study results and laws in the field are also introduced, which are from some scholars, the author of this paper.

  8. Initial settlements of rock fills on soft clay

    OpenAIRE

    Pedersen, Truls Martens

    2012-01-01

    Rock fills that hit the seabed will remold the underlying material. If this material is a clay with sufficiently low shear strength, it will adopt rheological properties, causing flow through the rock fill, and contributing to the initial settlements of the rock fill in addition to conventional consolidation theory. The settlements of the rocks depend upon the height of the rock fill and how the rocks have been laid out. This is due to the viscosity of the clay, and the fact that clay is thix...

  9. Rock melting technology and geothermal drilling

    Science.gov (United States)

    Rowley, J. C.

    1974-01-01

    National awareness of the potential future shortages in energy resources has heightened interest in exploration and utilization of a variety of geothermal energy (GTE) reservoirs. The status of conventional drilling of GTE wells is reviewed briefly and problem areas which lead to higher drilling costs are identified and R and D directions toward solution are suggested. In the immediate future, an expanded program of drilling in GTE formations can benefit from improvements in drilling equipment and technology normally associated with oil or gas wells. Over a longer time period, the new rock-melting drill bits being developed as a part of the Los Alamos Scientific Laboratory's Subterrene Program offer new solutions to a number of problems which frequently hamper GTE drilling, including the most basic problem - high temperature. Two of the most favorable characteristics of rock-melting penetrators are their ability to operate effectively in hot rock and produce glass linings around the hole as an integral part of the drilling process. The technical advantages to be gained by use of rock-melting penetrators are discussed in relation to the basic needs for GTE wells.

  10. Measurement of Discontinuity Characteristics in Rock Engineering

    International Nuclear Information System (INIS)

    It ranges in the base rock discontinuity surface (insulation) until currently as one of the variation past record which is recorded in the objective base rock, specially in about these geometric school register distribution quality research depth it makes be from the enterprise which demands the underground water flow interpretation of epidemiology stability and adiabatic watch concept of the base rock and it is made to accomplish and it is come. Discontinuity surface us from geological features site records the thing so is not the simple task. Discontinuity surface first of all, with the directivity which it specifies spatial it has the size of grudge together, according to site circumstance the case where the full investigation is difficult is numerous. Also, discontinuity surface it is measured from site if data the index outcrop, discontinuity surface the tunnel wall panel or the drill nose Oh it intersects discontinuity surface as not passing these people it has optional directivity within space of the base rock an only thing in the part comes seeming it is. It joins in and interpretation process of data from the population of the data which is investigated with parameter by presenting a representative value in what kind of form about also the consideration is necessary

  11. Accurate phase-shift velocimetry in rock

    Science.gov (United States)

    Shukla, Matsyendra Nath; Vallatos, Antoine; Phoenix, Vernon R.; Holmes, William M.

    2016-06-01

    Spatially resolved Pulsed Field Gradient (PFG) velocimetry techniques can provide precious information concerning flow through opaque systems, including rocks. This velocimetry data is used to enhance flow models in a wide range of systems, from oil behaviour in reservoir rocks to contaminant transport in aquifers. Phase-shift velocimetry is the fastest way to produce velocity maps but critical issues have been reported when studying flow through rocks and porous media, leading to inaccurate results. Combining PFG measurements for flow through Bentheimer sandstone with simulations, we demonstrate that asymmetries in the molecular displacement distributions within each voxel are the main source of phase-shift velocimetry errors. We show that when flow-related average molecular displacements are negligible compared to self-diffusion ones, symmetric displacement distributions can be obtained while phase measurement noise is minimised. We elaborate a complete method for the production of accurate phase-shift velocimetry maps in rocks and low porosity media and demonstrate its validity for a range of flow rates. This development of accurate phase-shift velocimetry now enables more rapid and accurate velocity analysis, potentially helping to inform both industrial applications and theoretical models.

  12. Fractures and Rock Mechanics, Phase 1

    DEFF Research Database (Denmark)

    Krogsbøll, Anette; Jakobsen, Finn; Madsen, Lena

    1997-01-01

    The main objective of the project is to combine geological descriptions of fractures, chalk types and rock mechanical properties in order to investigate whether the chosen outcrops can be used as analogues to reservoir chalks. This report deals with 1) geological descriptions of outcrop locality ...

  13. Life Found Lurking under Arctic Rocks

    Institute of Scientific and Technical Information of China (English)

    Sarah Graham; 刘晓

    2004-01-01

    @@ The Arctic tundra② would not appear a welcoming environment for life. But a paper published today in the journal Nature suggests that polar deserts may house photosynthetic③ organisms in a very unlikely place--under rocks. The discovery of the photosynthetic cyanobacteria④ could potentially double estimates of the carbon sequestration⑤ potential in these extreme environments.

  14. Optically stimulated luminescence dating of rock surfaces

    DEFF Research Database (Denmark)

    Sohbati, Reza

    parameter estimates based on first principles does not result in the expected exposure times. In an alternative approach a known-age quartz-rich sandstone is used for calibration, and the model is then used to constrain the likely age of an important Native American rock-art style. It is concluded...

  15. Insights on surface spalling of rock

    Science.gov (United States)

    Tarokh, Ali; Kao, Chu-Shu; Fakhimi, Ali; Labuz, Joseph F.

    2016-07-01

    Surface spalling is a complex failure phenomenon that features crack propagation and detachment of thin pieces of rock near free surfaces, particularly in brittle rock around underground excavations when large in situ stresses are involved. A surface instability apparatus was used to study failure of rock close to a free surface, and damage evolution was monitored by digital image correlation (DIC). Lateral displacement at the free face was used as the feedback signal to control the post-peak response of the specimen. DIC was implemented in order to obtain the incremental displacement fields during the spalling process. Displacement fields were computed in the early stage of loading as well as close to the peak stress. Fracture from the spalling phenomenon was revealed by incremental lateral displacement contours. The axial and lateral displacements suggested that the displacement gradient was uniform in both directions at early loading stages and as the load increased, the free-face effect started to influence the displacements, especially the lateral displacement field. A numerical approach, based on the discrete element method, was developed and validated from element testing. Damage evolution and localization observed in numerical simulations were similar to those observed in experiments. By performing simulations in two- and three-dimensions, it was revealed that the intermediate principal stress and platen-rock interfaces have important effects on simulation of surface spalling.

  16. Waste package performance in unsaturated rock

    International Nuclear Information System (INIS)

    The unsaturated rock and near-atmospheric pressure of the potential nuclear waste repository at Yucca Mountain present new problems of predicting waste package performance. In this paper we present some illustrations of predictions of waste package performance and discuss important data needs. 11 refs., 9 figs., 1 tab

  17. The riddles of rock and roll

    NARCIS (Netherlands)

    L.J.M. d' Anjou (Leo)

    2003-01-01

    textabstractRock and roll has often been equated with rebellion. The genre, though, is just a form of popular music and many of the important players in the game of promoting it were, like the saying goes, only in it for the money. As a rule, music like that will be supportive of the social order ra

  18. Strangulation injury from indigenous rocking cradle

    Directory of Open Access Journals (Sweden)

    Saha Abhijeet

    2010-01-01

    Full Text Available Indigenously made rocking cradle is frequently used in rural India. We report strangulation from an indigenously made rocking cradle in an 11-month-old female child. The unique mode of injury and its mechanism have been discussed. Strangulation is an important cause of homicidal and suicidal injury in adults but in children it is usually accidental leading to death due to asphyxia as a result of partial hanging. In western countries, it is the third most common cause of accidental childhood deaths, 17% of them being due to ropes and cords. It ranks fourth amongst the causes of unintentional injury in children less than 1 year of age following roadside accidents, drowning and burns. However, in India, strangulation injury is under reported although indigenous rocking cradles are very commonly used in rural India, and they are even more dangerous than the cribs and adult beds as there are no safety mechanisms therein. We report a case of accidental strangulation following suspension from an indigenously made rocking cradle. The unique mode of injury has prompted us to report this case.

  19. Hot-dry-rock geothermal resource 1980

    Energy Technology Data Exchange (ETDEWEB)

    Heiken, G.; Goff, F.; Cremer, G. (ed.)

    1982-04-01

    The work performed on hot dry rock (HDR) geothermal resource evaluation, site characterization, and geophysical exploration techniques is summarized. The work was done by region (Far West, Pacific Northwest, Southwest, Rocky Mountain States, Midcontinent, and Eastern) and limited to the conterminous US.

  20. Rock engineering: La Grande Complex, Quebec

    Energy Technology Data Exchange (ETDEWEB)

    Murphy, D.K.; Levay, J.

    1982-08-01

    The paper presents an overview of rock engineering considerations in the Complex as related particularly to excavation and support problems. Examples are chosen to show the range of geological conditions encountered together with the engineering philosophy that has governed their treatment. Experience gained with unlined tunnels and channels for hydraulic purposes is discussed.

  1. Ototraumatic effects of hard rock music.

    Science.gov (United States)

    Reddell, R C; Lebo, C P

    1972-01-01

    Temporary and permanent shifts in auditory thresholds were found in 43 hard rock musicians and temporary shifts were also observed in some listeners. The threshold shifts involved all of the conventional puretone test frequencies. Custom-fitted polyvinyl chloride ear protectors were found to be effective in prevention of these noise-induced hearing losses.

  2. Diffusion of uranium in the granite rock

    International Nuclear Information System (INIS)

    In the safety assessment of high level radioactive waste disposal, a significant retardation factor of radionuclides leaking from an underground repository can be expected. When radionuclides released from an underground repository are transported with the moving groundwater along cracks in the rock, the radionuclides will be retarded by not only adsorption on the surface of the cracks but also by process diffusion into submicron pores of rock matrix. In this experiments have been performed by process diffusion of uranium in water saturated granite. The measured penetration profile of uranium was composed of two parts. This profile was successfully explained by considering two diffusion paths in granite rock. One diffusion path was possibly a fissure with a width of few microns and another was a submicron pores of granite rock. The orders of magnitude of diffusivities for uranium were 10-12 m2/sec through the fissure and 1015 m2/sec through the submicron pores. The difference between the diffusivities of two path is thought to be caused by small geometrical factor of submicron pores, if to compared with fissures. (author)

  3. Fluorine geochemistry in volcanic rock series

    DEFF Research Database (Denmark)

    Stecher, Ole

    1998-01-01

    A new analytical procedure has been established in order to determine low fluorine concentrations (30–100 ppm F) in igneous rocks, and the method has also proven successful for higher concentrations (100–4000 ppm F). Fluorine has been measured in a series of olivine tholeiites from the Reykjanes ...

  4. Fractures and Rock Mechanics, Phase 1

    DEFF Research Database (Denmark)

    Havmøller, Ole; Krogsbøll, Anette

    1997-01-01

    The main objectives of the project are to combine geological description of fractures, chalk types and rock mechanical properties, and to investigate whether the chosen outcrops can be used as analogues to reservoir chalks. Five chalk types, representing two outcrop localities: Stevns and...

  5. Nonlinear Analysis of Cavities in Rock Salt

    DEFF Research Database (Denmark)

    Ottosen, N. S.; Krenk, Steen

    1979-01-01

    The paper covers some material and computational aspects of the rock mechanics of leached cavities in salt. A material model is presented in which the instantaneous stiffness of the salt is obtained by interpolation between the unloaded state and a relevant failure state. The model enables...

  6. Simulation of failure process of jointed rock

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    A modified discontinuous deformation analysis (DDA) algorithm was proposed to simulate the failure behavior of jointed rock.In the proposed algorithm,by using the Monte-Carlo technique,random joint network was generated in the domain of interest.Based on the joint network,the triangular DDA block system was automatically generated by adopting the advanced front method.In the process of generating blocks,numerous artificial joints came into being,and once the stress states at some artificial joints satisfy the failure criterion given beforehand,artificial joints will turn into real joints.In this way,the whole fragmentation process of rock mass can be replicated.The algorithm logic was described in detail,and several numerical examples were carried out to obtain some insight into the failure behavior of rock mass containing random joints.From the numerical results,it can be found that the crack initiates from the crack tip,the growth direction of the crack depends upon the loading and constraint conditions,and the proposed method can reproduce some complicated phenomena in the whole process of rock failure.

  7. Investigation of sport rock climbers’ handgrip strength

    Directory of Open Access Journals (Sweden)

    Burak Gürer

    2015-10-01

    Full Text Available This study aims to investigate handgrip strengths of elite sportsmen who are involved in sport rock climbing. Study group was composed of 144 sportsmen from 22 countries who participated in Petzl Roc Trip sport rock climbing festival held in Turkey between 14 and 19 October 2014. Data were collected by using Takei Grip-D brand hand dynamometer. The data collected were analyzed and interpreted by statistical package programme (SPSS 16.0. Results show meaningful differences between sportsmen’s right handgrip strength and left handgrip strength. Sportsmen’s right handgrip strength was found to be higher. Results differed based on gender as well. Left and right handgrip strength of males was found to be higher to those of females. No significant relationships were detected based on nationality, age, history of climbing and period of experience in climbing. Relationships were observed between Turkish male and female climbers’ right and left handgrip strengths. As a result, it can be claimed that right hand is used more often in sport rock climbing compared to the left hand. It is also believed that fingers and technique are crucial in sport rock climbing. Practices to develop finger strength and techniques are suggested.

  8. Radiocarbon dating of ancient rock paintings

    Energy Technology Data Exchange (ETDEWEB)

    Ilger, W.A.; Hyman, M.; Rowe, M.W. [Texas A and M Univ., College Station, TX (United States). Dept. of Chemistry; Southon, J. [Lawrence Livermore National Lab., CA (United States)

    1995-06-20

    This report presents progress made on a technique for {sup 14}C dating pictographs. A low-temperature oxygen plasma is used coupled with high-vacuum technologies to selectively remove C-containing material in the paints without contamination from inorganic carbon from rock substrates or accretions.

  9. Anthropometry of young competitive sport rock climbers

    OpenAIRE

    Watts, P.; Joubert, L; Lish, A; Van der Mast, J.; Wilkins, B.

    2003-01-01

    Background: Adult elite competitive rock climbers are small in stature with low body mass and very low body fat percentage. These characteristics have generated concern that young climbers may attempt body mass reduction to extreme levels with adverse consequences for health and performance. No published anthropometry data for young competitive climbers exist.

  10. Crowdsourcing Rock N' Roll Multimedia Retrieval

    NARCIS (Netherlands)

    C.G.M. Snoek; B. Freiburg; J. Oomen; R. Ordelman

    2010-01-01

    In this technical demonstration, we showcase a multimedia search engine that facilitates semantic access to archival rock n' roll concert video. The key novelty is the crowdsourcing mechanism, which relies on online users to improve, extend, and share, automatically detected results in video fragmen

  11. A laboratory apparatus for forced-oscillation experiments on partially saturated rocks

    Science.gov (United States)

    Musialak, Jana; Renner, Jörg; Steeb, Holger

    2016-04-01

    Seismic wave attenuation in partially saturated reservoir rocks is influenced by the physical properties of the porous rock and of the inherent pore fluids, including their local saturation state. Therefore, wave attenuation, when studied over a range of frequencies, can be useful to obtain valuable information on the morphology of partially saturated rocks. Quantitative estimates for pore-fluid content and saturation degree as well as fracture density are crucial for a substantial characterization of geothermal reservoirs and monitoring of processes in subsurface fluid-rock systems. Reservoir rocks, such as sandstones, can show heterogeneities of various sizes, starting from micro-cracks on the grain or micrometer scale to faults with several kilometers in length. Solid and fluid heterogeneities may lead to a patch-wise saturation state on the mesoscopic scale, i.e. the characteristic length scale of the patches is much larger than the dominant grain or pore size. The length scales of heterogeneities affect the characteristics of seismic attenuation. Studying this effect is important for the interpretation of seismic data, as obtained for geothermal reservoirs. Thus, we developed a new experimental setup to measure the effective hydro-mechanical properties of partially and fully saturated rock samples under realistic reservoir stress states in the seismic frequency range. This forced-oscillation apparatus is suitable for cylindrical rock samples with a diameter of 30 mm and a length of 75 mm. It is composed of a high-pressure triaxial cell which permits multistep in- and outflow of two different pore fluids under in situ pressure conditions, and a dynamic excitation device. This preloaded piezoelectric actuator with DMS-position sensor can generate a sinusoidal axial displacement that subjects the triaxially loaded sample to an additional harmonic stress with a frequency up to 1 kHz. The applied force is measured externally as well as inside the triaxial cell by a

  12. The Planar Shape of Rock Joints

    Science.gov (United States)

    Zhang, Lianyang; Einstein, Herbert H.

    2010-02-01

    Knowing the planar shape of discontinuities is important when characterizing discontinuities in a rock mass. However, the real discontinuity shape is rarely known, since the rock mass is usually inaccessible in three dimensions. Information on discontinuity shape is limited and often open to more than one interpretation. This paper discusses the planar shape of rock joints, the most common discontinuities in rock. First, a brief literature review about the shape of joints is presented, including some information on joint-surface morphology, inferences from observed trace lengths on different sampling planes, information based on experimental studies, and joint shapes assumed by different researchers. This review shows that joints not affected by adjacent geological structures such as bedding boundaries or pre-existing fractures tend to be elliptical (or approximately circular but rarely). Joints affected by or intersecting such geological structures tend to be rectangular. Then, using the general stereological relationship between trace length distributions and joint size distributions developed by Zhang et al. (Geotechnique 52(6):419-433, 2002) for elliptical joints, the effect of sampling plane orientation on trace lengths is investigated. This study explains why the average trace lengths of non-equidimensional (elliptical or similar polygonal) joints on two sampling planes can be about equal and thus the conclusion that rock joints are equidimensional (circular) drawn from the fact that the average trace lengths on two sampling planes are approximately equal can be wrong. Finally, methods for characterizing the shape and size of joints (elliptical or rectangular) from trace length data are recommended, and the appropriateness of using elliptical joint shapes to represent polygonal, especially rectangular, joints is discussed.

  13. Recent advances in analysis and prediction of Rock Falls, Rock Slides, and Rock Avalanches using 3D point clouds

    Science.gov (United States)

    Abellan, A.; Carrea, D.; Jaboyedoff, M.; Riquelme, A.; Tomas, R.; Royan, M. J.; Vilaplana, J. M.; Gauvin, N.

    2014-12-01

    The acquisition of dense terrain information using well-established 3D techniques (e.g. LiDAR, photogrammetry) and the use of new mobile platforms (e.g. Unmanned Aerial Vehicles) together with the increasingly efficient post-processing workflows for image treatment (e.g. Structure From Motion) are opening up new possibilities for analysing, modeling and predicting rock slope failures. Examples of applications at different scales ranging from the monitoring of small changes at unprecedented level of detail (e.g. sub millimeter-scale deformation under lab-scale conditions) to the detection of slope deformation at regional scale. In this communication we will show the main accomplishments of the Swiss National Foundation project "Characterizing and analysing 3D temporal slope evolution" carried out at Risk Analysis group (Univ. of Lausanne) in close collaboration with the RISKNAT and INTERES groups (Univ. of Barcelona and Univ. of Alicante, respectively). We have recently developed a series of innovative approaches for rock slope analysis using 3D point clouds, some examples include: the development of semi-automatic methodologies for the identification and extraction of rock-slope features such as discontinuities, type of material, rockfalls occurrence and deformation. Moreover, we have been improving our knowledge in progressive rupture characterization thanks to several algorithms, some examples include the computing of 3D deformation, the use of filtering techniques on permanently based TLS, the use of rock slope failure analogies at different scales (laboratory simulations, monitoring at glacier's front, etc.), the modelling of the influence of external forces such as precipitation on the acceleration of the deformation rate, etc. We have also been interested on the analysis of rock slope deformation prior to the occurrence of fragmental rockfalls and the interaction of this deformation with the spatial location of future events. In spite of these recent advances

  14. Definition and description of parameters for geologic, geophysical and rock mechanical mapping of rock

    International Nuclear Information System (INIS)

    This report presents how geologic parameters should be used in SKB rock mappings. Geologic parameters dominate, but some parameters can be seen as geophysical or mechanical. The report is structured in the main areas Rock type, Plastic structures and Brittle structures, according to the parameter grouping that specifies how the bedrock should be characterized at the SKB site investigations. Each parameter is presented in a common structure: Name in Swedish and English; Definition; Description; Determination; Classification; and Presentation form (in particular graphic)

  15. Compaction, rock property evolution and rock physics diagnostics of Askeladd discovery, Norwegian Barents Sea

    OpenAIRE

    2012-01-01

    Geologically, Barents Sea consists of platform areas and basins, covered by significant amounts of sedimentary rocks ranging from Paleozoic to Cenozoic age. Several phases of uplift have been occurred, highly influenced the petroleum systems in the region. Askeladd discovery is located in the Hammerfest Basin, South Western part of the Norwegian Barents Sea. In this study, reservoir characteristics of Stø Formation is evaluated according to compaction trends and rock physics diagnostics of fi...

  16. Simulation of fluorescence lidar for detecting oil slick%荧光激光雷达技术探测水面油污染系统仿真研究∗

    Institute of Scientific and Technical Information of China (English)

    景敏; 华灯鑫; 乐静

    2016-01-01

    为实现对水面油污染的探测,根据荧光激光雷达系统的发展趋势,采用激光诱导荧光技术,建立了适用于水面油污染探测荧光激光雷达的系统模型。提出采用单激光器结合增强电荷耦合器件的小型荧光激光雷达探测系统,通过分析激光器单脉冲能量与探测浓度之间的关系,结合荧光激光雷达系统参数,对系统模型的探测能力与信噪比等进行了数值仿真。结果表明,系统选用单脉冲能量50µJ的355 nm Nd:YAG激光器作为激发光源,白天在7 m的距离处探测信噪比可以达到10,满足实验室搭建模拟系统的要求。针对实际探测水面油污染,提出采用增大激光器功率的方法,并通过模拟计算验证了采用50 mJ的单脉冲能量激光器在230 m的探测距离处可得到与实验室相同的结果,对实际系统的搭建具有指导意义。%In order to measure the oil pollution on water surface, a fluorescence lidar model system based on laser induced fluorescence is put forward for detecting oil slick. The system model and fluorescence detecting principle are described in detail. According to the properties of detected material, wavelength of laser and filter of receiving system are adopted to ensure that the lidar system is operated at the peak wavelength. Following the development trend of miniaturization in the world, using single laser and intensified charge-coupled devices, a small fluorescence detecting system is designed. FTSS 350-50 laser made by CRYLAS company, with compact dimension, low weight and excellent energy efficiency, and PI-MAX4 intensified charge-couple devices made by Princeton Instruments company, with good time resolution characteristic, are selected to produce laser as a launch device and to inspect fluorescence lifetime and capture image as a receiving device, respectively. The laser excitation wavelength, the energy of laser, the center wavelength and bandwidth of filter, the received echo

  17. Petrological Investigation on the Rock Sample of Rock Garden in the Schoolyard, Korea

    Science.gov (United States)

    Cho, Kyu-Seong

    2014-05-01

    The effective teaching of Earth Science in the classroom should be augmented by field studies of rocks and minerals in a competently designed school rock garden(SRG). The displayed specimens must be correctly identified, labeled and esthetically evaluated. SRG is more than a general garden with just landscaping and it should provide students with freedom of conducting independent inquiries. The composition of the selected specimens should be representative of the bedrocks of region as well as of Korea in general. There are 130 schools in Jeonju-city and 35 (26.9%) have established rock gardens. There is a pressing demand for more gardens and number of display samples in school. The existing displays need improvement because some samples are not correctly identified and labeled. In addition, there is a duplication of rock types as well as lack of important rock types. The number and composition of the displayed rocks and minerals should be related to the school curriculum and reflect representative bedrocks of Jeonju-city and region.

  18. Petrological modeling of basaltic rocks from Venus: a case for the presence of silicic rocks

    Science.gov (United States)

    Shellnutt, J. G.

    2013-12-01

    The presence of highly evolved igneous rocks on Venus is debated. The formation of highland terranes and pancake domes are the two principle tectonic and volcanic features which argue in favor of the presence of silicic igneous rocks; however, the lack of water on Venus casts doubt on whether or not granites and rhyolites can form. Data returned to Earth from the Venera 13 and 14 landers show that the surface of Venus is comprised of basaltic rocks similar in composition to those found on Earth. Here is it shown that anhydrous and hydrous fractional crystallization modeling using the Venera 13 and 14 data as starting materials can produce compositions similar to terrestrial phonolites and rhyolites. It is suggested that at shallow crustal levels (i.e. ≤ 0.1 GPa) mafic magmas can differentiate into silicic magmas resembling phonolites or rhyolites which may or may not erupt. Furthermore, the hydrous equilibrium partial melting models can produce rocks similar to terrestrial andesites and rhyolites whereas anhydrous models suggest there may be a uniquely Venusian type of silicic rock. The silicic rocks, if present, could act as ';continental nucleation' sites and/or their presence may facilitate preferential sites of shearing and deformation of the Venusian crust.

  19. Rock Drilling Performance Evaluation by an Energy Dissipation Based Rock Brittleness Index

    Science.gov (United States)

    Munoz, H.; Taheri, A.; Chanda, E. K.

    2016-08-01

    To reliably estimate drilling performance both tool-rock interaction laws along with a proper rock brittleness index are required to be implemented. In this study, the performance of a single polycrystalline diamond compact (PDC) cutter cutting and different drilling methods including PDC rotary drilling, roller-cone rotary drilling and percussive drilling were investigated. To investigate drilling performance by rock strength properties, laboratory PDC cutting tests were performed on different rocks to obtain cutting parameters. In addition, results of laboratory and field drilling on different rocks found elsewhere in literature were used. Laboratory and field cutting and drilling test results were coupled with values of a new rock brittleness index proposed herein and developed based on energy dissipation withdrawn from the complete stress-strain curve in uniaxial compression. To quantify cutting and drilling performance, the intrinsic specific energy in rotary-cutting action, i.e. the energy consumed in pure cutting action, and drilling penetration rate values in percussive action were used. The results show that the new energy-based brittleness index successfully describes the performance of different cutting and drilling methods and therefore is relevant to assess drilling performance for engineering applications.

  20. Aespoe hard rock laboratory. Annual report 2000

    International Nuclear Information System (INIS)

    The Aespoe Hard Rock Laboratory constitutes an important component of SKB's work to design, construct, and implement a deep geological repository for spent nuclear fuel and to develop and test methods for characterisation of selected repository sites. The retention effect of the rock has been studied by tracer tests in the Tracer Retention Understanding Experiments (TRUE) and the TRUE Block Scale (TRUE BS). These tests are supplemented by the new Long Term Diffusion Experiment (LTDE). During year 2000 the field experiments of TRUE BS (50 m scale) were completed and preparations made for the LTDE (migration through a fracture wall and into the rock), including boring of approximately 10 m deep hole with 300 mm diameter. Laboratory investigations have difficulties in simulating natural conditions and need supplementary field studies to support validation exercises. A special borehole probe, CHEMLAB, has therefore been designed for different kinds of validation experiments where data can be obtained representative for the in-situ properties of groundwater at repository depth. During 2000 migration experiments were made with actinides (Am, Np and Pu) in CHEMLAB 2, the simplified supplement to CHEMLAB 1. Colloids of nuclides as well as of bentonite might affect the migration of released radionuclides and a separate project was planned during 2000 to assess the existence, stability and mobility of colloids. The development of numerical modelling tools continues with the general objective to improve the numerical models in terms of flow and transport and to update the site-scale and laboratory scale models for the Aespoe HRL. The Matrix Fluid Chemistry project aims at determining the origin and age of matrix fluids and the experiment has been designed to sample matrix fluids from predetermined, isolated borehole sections by specialised equipment. The Aespoe HRL also has the task to demonstrate and perform full scale tests of the function of different components of the

  1. Aespoe Hard Rock Laboratory. Annual Report 2009

    Energy Technology Data Exchange (ETDEWEB)

    2010-12-15

    The Aespoe Hard Rock Laboratory (HRL) is an important part of SKB's work with the design and construction of a deep geological repository for the final disposal of spent nuclear fuel. Aespoe HRL is located in the Simpevarp area in the municipality of Oskarshamn. One of the fundamental reasons behind SKB's decision to construct an underground laboratory was to create opportunities for research, development and demonstration in a realistic and undisturbed rock environment down to repository depth. The underground part of the laboratory consists of a tunnel from the Simpevarp peninsula to the southern part of Aespoe where the tunnel continues in a spiral down to a depth of 460 m. Aespoe HRL has been in operation since 1995 and considerable international interest has been shown in its research, as well as in the development and demonstration tasks. A summary of the work performed at Aespoe HRL during 2009 is given below. Geoscience Geoscientific research is a basic activity at Aespoe HRL. The aim of the current studies is to develop geoscientific models of the Aespoe HRL and increase the understanding of the rock mass properties as well as knowledge of applicable methods of measurement. A main task within the geoscientific field is the development of the Aespoe Site Descriptive Model (SDM) integrating information from the different fields. The main activities in the geoscientific fields have been: (1) Geology evaluation of geological mapping techniques leading to the decision to develop a SKB mapping system and finalization of the mapping of rock surfaces in the new tunnel, (2) Hydrogeology monitoring and storage of data in the computerised Hydro Monitoring System, (3) Geochemistry sampling of groundwater in the yearly campaign and for specific experiments and (4) Rock Mechanics finalised the field tests on thermally-induced spalling in deposition holes and evaluated the effect of counterforce in the deposition holes. Natural barriers At Aespoe HRL

  2. Aespoe Hard Rock Laboratory. Annual Report 2009

    International Nuclear Information System (INIS)

    The Aespoe Hard Rock Laboratory (HRL) is an important part of SKB's work with the design and construction of a deep geological repository for the final disposal of spent nuclear fuel. Aespoe HRL is located in the Simpevarp area in the municipality of Oskarshamn. One of the fundamental reasons behind SKB's decision to construct an underground laboratory was to create opportunities for research, development and demonstration in a realistic and undisturbed rock environment down to repository depth. The underground part of the laboratory consists of a tunnel from the Simpevarp peninsula to the southern part of Aespoe where the tunnel continues in a spiral down to a depth of 460 m. Aespoe HRL has been in operation since 1995 and considerable international interest has been shown in its research, as well as in the development and demonstration tasks. A summary of the work performed at Aespoe HRL during 2009 is given below. Geoscience Geoscientific research is a basic activity at Aespoe HRL. The aim of the current studies is to develop geoscientific models of the Aespoe HRL and increase the understanding of the rock mass properties as well as knowledge of applicable methods of measurement. A main task within the geoscientific field is the development of the Aespoe Site Descriptive Model (SDM) integrating information from the different fields. The main activities in the geoscientific fields have been: (1) Geology evaluation of geological mapping techniques leading to the decision to develop a SKB mapping system and finalization of the mapping of rock surfaces in the new tunnel, (2) Hydrogeology monitoring and storage of data in the computerised Hydro Monitoring System, (3) Geochemistry sampling of groundwater in the yearly campaign and for specific experiments and (4) Rock Mechanics finalised the field tests on thermally-induced spalling in deposition holes and evaluated the effect of counterforce in the deposition holes. Natural barriers At Aespoe HRL, experiments are

  3. Elu on Rock 'n' roll! / Mari Hiiemäe

    Index Scriptorium Estoniae

    Hiiemäe, Mari

    2007-01-01

    Üritusesarjast "The 1st Tallinn Rocknroll Weekend Party" (korraldaja Eero Palusalu) Tallinnas Rock Cafés. Inglise rockansamblitest Matchbox ja Crazy Cavan & The Rhythm Rockers (kontsert 15. sept. Rock Cafés)

  4. Rock slope instabilities in Norway: First systematic hazard and risk classification of 22 unstable rock slopes

    Science.gov (United States)

    Böhme, Martina; Hermanns, Reginald L.; Oppikofer, Thierry; Penna, Ivanna

    2016-04-01

    Unstable rock slopes that can cause large failures of the rock-avalanche type have been mapped in Norway for almost two decades. Four sites have earlier been characterized as high-risk objects based on expertise of few researchers. This resulted in installing continuous monitoring systems and set-up of an early-warning system for those four sites. Other unstable rock slopes have not been ranked related to their hazard or risk. There are ca. 300 other sites known of which 70 sites were installed for periodic deformation measurements using multiple techniques (Global Navigation Satellite Systems, extensometers, measurement bolts, and others). In 2012 a systematic hazard and risk classification system for unstable rock slopes was established in Norway and the mapping approach adapted to that in 2013. Now, the first 22 sites were classified for hazard, consequences and risk using this classification system. The selection of the first group of sites to be classified was based on an assumed high hazard or risk and importance given to the sites by Norwegian media and the public. Nine of the classified 22 unstable rock slopes are large sites that deform inhomogeneously or are strongly broken up in individual blocks. This suggests that different failure scenarios are possible that need to be analyzed individually. A total of 35 failure scenarios for those nine unstable rock slopes were considered. The hazard analyses were based on 9 geological parameters defined in the classification system. The classification system will be presented based on the Gamanjunni unstable rock slope. This slope has a well developed back scarp that exposes 150 m preceding displacement. The lateral limits of the unstable slope are clearly visible in the morphology and InSAR displacement data. There have been no single structures observed that allow sliding kinematically. The lower extend of the displacing rock mass is clearly defined in InSAR data and by a zone of higher rock fall activity. Yearly

  5. Rock mass classification and tunnel support design in China

    OpenAIRE

    Wangh, SJ; Lee, CF; Kwong, AKL

    2003-01-01

    This paper presents and discusses the two recently established rock mass classification systems in China, namely the Basic Quality (BQ) and Host Rock Rating (HRR) systems. The establishment of the BQ and HRR rock mass classification systems in China is based on huge amount of experiences gathered in the design stages and later verified in the construction of rock tunnels and underground structures in China. The BQ system was originally used for classification ...

  6. Stress analysis of single joint rock mass under triaxial compression

    Institute of Scientific and Technical Information of China (English)

    LIU Xin-rong(刘新荣); JIANG Shu-ping(蒋树屏); LI Xiao-hong(李晓红); BAO Tai(包太)

    2004-01-01

    Based on the fundamental principle of rock mechanics, the stresses of single joint rock mass under three-dimensional compression were analyzed. The effect of the intermediate principle stress on the strength of single joint rock mass were discussed in particular. It is found that the strength of single joint rock are affected by the intermediate principal stress, which may be the main factor in some conditions.

  7. Latest progress of soft rock mechanics and engineering in China

    OpenAIRE

    Manchao He

    2014-01-01

    The progress of soft rock mechanics and associated technology in China is basically accompanied by the development of mining engineering and the increasing disasters of large rock deformation during construction of underground engineering. In this regard, Chinese scholars proposed various concepts and classification methods for soft rocks in terms of engineering practices. The large deformation mechanism of engineering soft rocks is to be understood through numerous experiments; and thus a co...

  8. Image Segmentation for rock fractures based on ARMA model

    OpenAIRE

    P. Seetal,; N.Natarajan

    2010-01-01

    Rock fracture mapping is very important in many applications related to rock mechanics. The toughest task is the extraction of the fractures from the images of the rocks. Time series model has been used in this paper for segmentation of fractures from the rock images. The model is compared with orthodox edge detection algorithms. A first order autoregressive image model has been implemented. The model has been applied for both rough as well as smooth fractures. The model was observed to perfo...

  9. Influence Mechanism of Grouting on Mechanical Characteristics of Rock Mass

    OpenAIRE

    Zhang Jixun; Shu Jiaqing; Ren Xuhua; Ren Hongyun

    2013-01-01

    Grouting technology has been widely used in all fields of geotechnical and civil engineering. Prospective engineering objectives including reinforcement of rock mass and groundwater leakage treatment can be achieved by grouting which will change the mechanical parameters of rock mass such as strength, elastic modulus, and coefficient of permeability. In this paper, rock mass is assumed as a composite material consisting of rock particles and random microcracks initially. Since part or all of ...

  10. 10 CFR 960.5-2-9 - Rock characteristics.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Rock characteristics. 960.5-2-9 Section 960.5-2-9 Energy... Rock characteristics. (a) Qualifying condition. The site shall be located such that (1) the thickness and lateral extent and the characteristics and composition of the host rock will be suitable...

  11. Dredging Processes I: The Cutting of Sand, Clay & Rock - Theory

    NARCIS (Netherlands)

    Miedema, S.A.

    2013-01-01

    This book gives an overview of cutting theories. It starts with a generic model, which is valid for all types of soil (sand, clay and rock) after which the specifics of dry sand, water saturated sand, clay, rock and hyperbaric rock are covered. For each soil type small blade angles and large blade a

  12. Rock mass classification and their uses in mining

    OpenAIRE

    Doneva, Nikolinka; Dambov, Risto; Hadzi-Nikolova, Marija

    2013-01-01

    The rock mass type in which all perform mining activities is of particular importance when choosing appropriate techniques and technologies to open the mine and exploitation of mineral resources. This paper presents the rock mass classification that is mostly used in mining. Also an example of rock mass classification according to Bienawski is provided

  13. Rock mechanics activities at the Waste Isolation Pilot Plant

    International Nuclear Information System (INIS)

    The application of rock mechanics at nuclear waste repositories is a true multidisciplinary effort. A description and historical summary of the Waste Isolation Pilot Plant (WIPP) is presented. Rock mechanics programs at the WIPP are outlined, and the current rock mechanics modeling philosophy of the Westinghouse Waste Isolation Division is discussed

  14. Experimental investigation of incipient shear failure in foliated rock

    NARCIS (Netherlands)

    Ikari, Matt J.; Niemeijer, André R.; Marone, Chris

    2015-01-01

    It has long been known that rock fabric plays a key role in dictating rock strength and rheology throughout Earth's crust; however the processes and conditions under which rock fabric impacts brittle failure and frictional strength are still under investigation. Here, we report on laboratory experim

  15. Study on mechanical parameters of fractured rock masses

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    The equivalent strength parameters of fractured rock masses are prerequisite for stability analysis of geotechnical engineering projects constructed in fractured rock masses which are encountered frequently in western china.Based on generated mesh of fractured rock masses,combined with statistic damage constitutive model of intact rock and damage model of structural plane,progressive failure of fractured rock masses is studied using finite element method(FEM) .Furthermore,Scale effect and anisotropy of compressive strength of fractured rock masses are studied.Study results show that the strength decreases and tend towards stability rapidly from intact rock to fractured rock masses,and the anisotropy of strength of fractured rock masses is not significant.At last,based on numerical simulation conducted on 10 m scale rock masses under different confining pressures,the equivalent strength parameters of fractured rock masses are gained and the results are compared with Hoek-Brown criteria.The method developed is helpful for determination of strength parameters of fractured rock masses.

  16. Upscaling of permeability field of fractured rock system: Numerical examples

    KAUST Repository

    Bao, K.

    2012-01-01

    When the permeability field of a given porous medium domain is heterogeneous by the existence of randomly distributed fractures such that numerical investigation becomes cumbersome, another level of upscaling may be required. That is such complex permeability field could be relaxed (i.e., smoothed) by constructing an effective permeability field. The effective permeability field is an approximation to the real permeability field that preserves certain quantities and provides an overall acceptable description of the flow field. In this work, the effective permeability for a fractured rock system is obtained for different coarsening scenarios starting from very coarse mesh all the way towards the fine mesh simulation. In all these scenarios, the effective permeability as well as the pressure at each cell is obtained. The total flux at the exit boundary is calculated in all these cases, and very good agreement is obtained.

  17. Aespoe hard rock laboratory. Annual report 2010

    Energy Technology Data Exchange (ETDEWEB)

    2011-02-15

    The Aespoe Hard Rock Laboratory (HRL) is an important part of SKB's work with the design and construction of a deep geological repository for the final disposal of spent nuclear fuel. Aespoe HRL is located in the Simpevarp area in the municipality of Oskarshamn. One of the fundamental reasons behind SKB's decision to construct an underground laboratory was to create opportunities for research, development and demonstration in a realistic and undisturbed rock environment down to repository depth. The underground part of the laboratory consists of a tunnel from the Simpevarp peninsula to the southern part of Aespoe where the tunnel continues in a spiral down to a depth of 460 m. Aespoe HRL has been in operation since 1995 and considerable international interest has been shown in its research, as well as in the development and demonstration tasks. A summary of the work performed at Aespoe HRL during 2010 is given below

  18. Organic Petrological Studies on Immature Source Rocks

    Institute of Scientific and Technical Information of China (English)

    李贤庆; 熊波; 钟宁宁; 马安来; 王铁冠; 张爱云

    2004-01-01

    Organic petrology is a marginal science that is quite practicable. At present, it has developed into a routine research tool that is widely applied in petroleum exploration and assessment. Based on several years' research of the authors, this paper presents the advances in organic petrological studies on immature source rocks, including the classification and characteristics of macerals, the composition of macerals and types of organic matter, the abundance and evolution of organic matter, oil-prone macerals, hydrocarbon generation and expulsion. All these results show that organic petrology is of considerable value pertaining to its application in the assessment of immature oil and gas. The immature source rocks consist of various macerals with obvious heterogeneity, contain different hydrocarbon-generating macerals with different oil thresholds and oil peaks, and show a two-staged evolutionary pattern of organic matter.

  19. Aespoe hard rock laboratory. Annual report 1992

    International Nuclear Information System (INIS)

    The Aespoe hard rock laboratory is being constructed in preparation for the deep geological repository of spent fuel in Sweden. This Annual report 1992 for the Aespoe hard rock laboratory contains an overview of the work conducted. Present work is focused on verification of pre-investigation methods and development of the detailed investigation methodology. Construction of the facility and investigation of the bedrock are being carried out in parallel. December 1992 1925 m of the tunnel has been excavated to a depth of 255 m below surface. An important and integrated part of the work is further refinement of conceptual and numerical models for groundwater flow and radionuclide migration. This work is carried out in cooperation with seven organizations from six countries that participate in the project. (25 refs.)

  20. Aespoe Hard Rock Laboratory. Annual Report 2011

    International Nuclear Information System (INIS)

    The Aespoe Hard Rock Laboratory (HRL) is an important part of SKB's work with the design and construction of a deep geological repository for the final disposal of spent nuclear fuel. Aespoe HRL is located in the Simpevarp area in the municipality of Oskarshamn. One of the fundamental reasons behind SKB's decision to construct an underground laboratory was to create opportunities for research, development and demonstration in a realistic and undisturbed rock environment down to repository depth. The underground part of the laboratory consists of a tunnel from the Simpevarp peninsula to the southern part of Aespoe where the tunnel continues in a spiral down to a depth of 460 m. Aespoe HRL has been in operation since 1995 and considerable international interest has been shown in its research, as well as in the development and demonstration tasks. A summary of the work performed at Aespoe HRL during 2011 is given below

  1. Mining Wikipedia to Rank Rock Guitarists

    Directory of Open Access Journals (Sweden)

    Muazzam A. Siddiqui

    2015-11-01

    Full Text Available We present a method to find the most influential rock guitarist by applying Google PageRank algorithm to information extracted from Wikipedia articles. The influence of a guitarist was estimated by the number of guitarists citing him/her as an influence and the influence of the latter. We extracted this who-influenced-whom data from the Wikipedia biographies and converted them to a directed graph where a node represented a guitarist and an edge between two nodes indicated the influence of one guitarist over the other. Next we used Google PageRank algorithm to rank the guitarists. The results are most interesting and provide a quantitative foundation to the idea that most of the contemporary rock guitarists are influenced by early blues guitarists. Although no direct comparison exist, the list was still validated against a number of other best-of lists available online and found to be mostly compatible.

  2. The physics of rock failure and earthquakes

    CERN Document Server

    Ohnaka, Mitiyasu

    2013-01-01

    Despite significant advances in the understanding of earthquake generation processes and derivation of underlying physical laws, controversy remains regarding the constitutive law for earthquake ruptures and how it should be formulated. Laboratory experiments are necessary to obtain high-resolution measurements that allow the physical nature of shear rupture processes to be deduced, and to resolve the controversy. This important book provides a deeper understanding of earthquake processes from nucleation to their dynamic propagation. Its key focus is a deductive approach based on laboratory-derived physical laws and formulae, such as a unifying constitutive law, a constitutive scaling law, and a physical model of shear rupture nucleation. Topics covered include: the fundamentals of rock failure physics, earthquake generation processes, physical scale dependence, and large-earthquake generation cycles. Designed for researchers and professionals in earthquake seismology, rock failure physics, geology and earthq...

  3. Radionuclide retardation in crystalline rock fractures

    Energy Technology Data Exchange (ETDEWEB)

    Hoelttae, P.; Hakanen, M.; Siitari-Kauppi, M. [Univ. of Helsinki (Finland). Dept. of Radiochemistry; Hautojaervi, A.

    1995-12-31

    Transport and retardation of slightly sorbing sodium was studied in Syyry area SY-KR7 mica gneiss and in altered porous tonalite. Experiments were performed using dynamic fracture and crushed rock column methods and the static batch method. Flow conditions in the column were determined using tritiated water and chloride as non-sorbing tracers. {sup 14}C-PMMA method was used to study the pore structure of matrices and the surface areas were determined by B.E.T. method. Sodium was retarded strongly in altered tonalite owing to homogeneous porous matrix structure and the composition of alteration minerals. An agreement between retardation values in batch and crushed rock column experiments as well as in fracture column experiments was good.

  4. Aespoe Hard Rock Laboratory. Annual Report 2011

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-03-15

    The Aespoe Hard Rock Laboratory (HRL) is an important part of SKB's work with the design and construction of a deep geological repository for the final disposal of spent nuclear fuel. Aespoe HRL is located in the Simpevarp area in the municipality of Oskarshamn. One of the fundamental reasons behind SKB's decision to construct an underground laboratory was to create opportunities for research, development and demonstration in a realistic and undisturbed rock environment down to repository depth. The underground part of the laboratory consists of a tunnel from the Simpevarp peninsula to the southern part of Aespoe where the tunnel continues in a spiral down to a depth of 460 m. Aespoe HRL has been in operation since 1995 and considerable international interest has been shown in its research, as well as in the development and demonstration tasks. A summary of the work performed at Aespoe HRL during 2011 is given below.

  5. Rupture by Damage Accumulation in Rocks

    CERN Document Server

    Amitrano, David

    2006-01-01

    The deformation of rocks is associated with microcracks nucleation and propagation, i.e. damage. The accumulation of damage and its spatial localization lead to the creation of a macroscale discontinuity, so-called "fault" in geological terms, and to the failure of the material, i.e. a dramatic decrease of the mechanical properties as strength and modulus. The damage process can be studied both statically by direct observation of thin sections and dynamically by recording acoustic waves emitted by crack propagation (acoustic emission). Here we first review such observations concerning geological objects over scales ranging from the laboratory sample scale (dm) to seismically active faults (km), including cliffs and rock masses (Dm, hm). These observations reveal complex patterns in both space (fractal properties of damage structures as roughness and gouge), time (clustering, particular trends when the failure approaches) and energy domains (power-law distributions of energy release bursts). We use a numerical...

  6. Aespoe hard rock laboratory. Annual report 2010

    International Nuclear Information System (INIS)

    The Aespoe Hard Rock Laboratory (HRL) is an important part of SKB's work with the design and construction of a deep geological repository for the final disposal of spent nuclear fuel. Aespoe HRL is located in the Simpevarp area in the municipality of Oskarshamn. One of the fundamental reasons behind SKB's decision to construct an underground laboratory was to create opportunities for research, development and demonstration in a realistic and undisturbed rock environment down to repository depth. The underground part of the laboratory consists of a tunnel from the Simpevarp peninsula to the southern part of Aespoe where the tunnel continues in a spiral down to a depth of 460 m. Aespoe HRL has been in operation since 1995 and considerable international interest has been shown in its research, as well as in the development and demonstration tasks. A summary of the work performed at Aespoe HRL during 2010 is given below

  7. Groundwater from Lower Cretaceous rocks in Kansas

    Science.gov (United States)

    Keene, Katherine M.; Bayne, Charles Knight

    1976-01-01

    Sandstones in Lower Cretaceous rocks contain supplies, of water that may be adequate to meet increasing present and future demands for supplemental municipal and domestic use in central and western Kansas. An estimated 70 to 80 million acre-feet (86,000 to 99,000 cubic hectometers) of water containing less than 1,000 milligrams per liter dissolved solids may be acceptable for use at the present (1976). An additional 10 to 15 million acre-feet (12,000 to 18,000 cubic hectometers) containing 1,000 to 3,000 milligrams per liter dissolved solids is estimated to be available for use in the future with appropriate desalinization. Lower Cretaceous rocks crop out from Washington County on the north to Comanche County on-the south. The rocks dip from a structural high in the southwest part of the State to structural lows in the northwest and north-central part. Depth below land surface increases generally northwestward to about 2,600 feet (790 meters); thickness of the rocks increases westward, nearly zero to about 850 feet (260 meters). The rocks consist chiefly of marine to nonmarine shale and silt- stone interbedded with coastal to deltaic sandstone. The interbedded sandstone, which composes about one-third of the rocks, consists of one or more lenses that thicken westward to about 400 feet (120 meters) in the central part of western Kansas. The yield of water to individual wells is related to areal extent, thickness, and interconnection of the sand lenses and to grain size and cementation of the sand. Large amounts of water may be pumped by wells where loosely cemented sand lenses are interconnected. Wells commonly yield adequate supplies for domestic and stock use; reported yields from municipal and irrigation wells range from about 100 to 2,000 gallons per minute (6 to 125 liters per second). Recharge to the Lower Cretaceous-rocks occurs in the area of outcrop and from hydraulically connected saturated Cenozoic rocks, especially in the southern part of the State

  8. MODELING UNDERGROUND STRUCTURE VULNERABILITY IN JOINTED ROCK

    Energy Technology Data Exchange (ETDEWEB)

    R. SWIFT; D. STEEDMAN

    2001-02-01

    The vulnerability of underground structures and openings in deep jointed rock to ground shock attack is of chief concern to military planning and security. Damage and/or loss of stability to a structure in jointed rock, often manifested as brittle failure and accompanied with block movement, can depend significantly on jointed properties, such as spacing, orientation, strength, and block character. We apply a hybrid Discrete Element Method combined with the Smooth Particle Hydrodynamics approach to simulate the MIGHTY NORTH event, a definitive high-explosive test performed on an aluminum lined cylindrical opening in jointed Salem limestone. Representing limestone with discrete elements having elastic-equivalence and explicit brittle tensile behavior and the liner as an elastic-plastic continuum provides good agreement with the experiment and damage obtained with finite-element simulations. Extending the approach to parameter variations shows damage is substantially altered by differences in joint geometry and liner properties.

  9. Retention processes in clay-rocks

    OpenAIRE

    Tournassat, Christophe; Grangeon, Sylvain

    2015-01-01

    International audience Within the context of the clay barrier concept for underground nuclear waste storage, montmorillonite and bentonite have been widely used as reference materials for radionuclides (RN) retention studies. Associated modeling work aims at understanding and predicting the retention of RN in clay-rocks where clay minerals are assumed to be representative of the most reactive phases. This " bottom-up " approach relies on a good confidence in the mechanistic understanding o...

  10. Rock Slopes from Mechanics to Decision Making

    OpenAIRE

    Einstein, H.H.; Sousa, R.L.; Karam, K.; Manzella, Irène; Kveldsvik, V.

    2010-01-01

    Rock slope instabilities are discussed in the context of decision making for risk assessment and management. Hence, the state of the slope and possible failure mechanism need to be defined first. This is done with geometrical and mechanical models for which recent developments are presented. This leads with appropriate consideration of uncertainties to risk determination and to the description of tools for risk management through active and passive countermeasures, including warning systems. ...

  11. El rock como conformador de identidades juveniles

    Directory of Open Access Journals (Sweden)

    Adrián de Garay

    1996-04-01

    Full Text Available El autor analiza la relación entre el rock y las identidades juveniles, a partir del abordaje de cinco “estilos” que se pueden identificar como constitutivos de éstas identidades. Ellos son: la jerga, la estética, las producciones culturales, los no-lugares y el territorio. Finaliza el artículo señalando algunos hitos importantes de la culturarockera en la ciudad de México.

  12. Low pore connectivity in natural rock

    Science.gov (United States)

    Hu, Qinhong; Ewing, Robert P.; Dultz, Stefan

    2012-05-01

    As repositories for CO2 and radioactive waste, as oil and gas reservoirs, and as contaminated sites needing remediation, rock formations play a central role in energy and environmental management. The connectivity of the rock's porespace strongly affects fluid flow and solute transport. This work examines pore connectivity and its implications for fluid flow and chemical transport. Three experimental approaches (imbibition, tracer concentration profiles, and imaging) were used in combination with network modeling. In the imbibition results, three types of imbibition slope [log (cumulative imbibition) vs. log (imbibition time)] were found: the classical 0.5, plus 0.26, and 0.26 transitioning to 0.5. The imbibition slope of 0.26 seen in Indiana sandstone, metagraywacke, and Barnett shale indicates low pore connectivity, in contrast to the slope of 0.5 seen in the well-connected Berea sandstone. In the tracer profile work, rocks exhibited different distances to the plateau porosity, consistent with the pore connectivity from the imbibition tests. Injection of a molten metal into connected pore spaces, followed by 2-D imaging of the solidified alloy in polished thin sections, allowed direct assessment of pore structure and lateral connection in the rock samples. Pore-scale network modeling gave results consistent with measurements, confirming pore connectivity as the underlying cause of both anomalous behaviors: imbibition slope not having the classical value of 0.5, and accessible porosity being a function of distance from the edge. A poorly connected porespace will exhibit anomalous behavior in fluid flow and chemical transport, such as a lower imbibition slope (in air-water system) and diffusion rate than expected from classical behavior.

  13. Stoke's efficiency of temporally rocked ratchets

    OpenAIRE

    Krishnan, Raishma; Chacko, Jim; Sahoo, Mamata; Jayannavar, A. M.

    2006-01-01

    We study the generalized efficiency of an adiabatically rocked ratchet with both spatial and temporal asymmetry. We obtain an analytical expression for the generalized efficiency in the deterministic case. Generalized efficiency of the order of 50% is obtained by fine tuning of the parameter range. This is unlike the case of thermodynamic efficiency where we could readily get an enhanced efficiency of upto 90%. The observed higher values of generalized efficiency is attributed to be due to th...

  14. Mining technology development for hard rock excavation

    International Nuclear Information System (INIS)

    A research facility has been established in the granitic gneiss of the CSM Experimental Mine at Idaho Springs, Colorado, for the purpose of evaluating/developing mining, geologic and geotechnical procedures appropriate for use in establishing nuclear waste repositories in hard rock. An experimental room has been excavated using careful blasting procedures. The extent and magnitude of blast damage is being evaluated. Structural geology is being mapped to assess continuity

  15. Spectrophotometric determination of fluorine in silicate rocks

    Science.gov (United States)

    Peck, L.C.; Smith, V.C.

    1964-01-01

    The rock powder is sintered with a sodium carbonate flux containing zinc oxide and magnesium carbonate, the sinter-cake leached with water and the resulting solution filtered. Fluorine is separated from the acidified filtrate by steam distillation and determined spectrophotometrically by means of a zirconium-SPADNS reagent. If a multiple-unit distillation apparatus is used, 12 determinations can be completed per man-day. ?? 1964.

  16. Sondierbohrung Boettstein: Hydrogeological testing of crystalline rocks

    International Nuclear Information System (INIS)

    In addition to comprehensive studies in geology, geophysics, hydrochemistry and rock mechanics, a three-phased program for (1) drilling (2) testing and (3) monitoring of the twelve boreholes was proposed. The Boettstein borehole is located in the central part of the target areas. It was the first borehole to be drilled. Drilling in the crystalline granitic basement rocks started at a depth of 315 m below ground surface in November 1982 and was completed in December 1983. The monitoring phase is on-going at this time. The study reported herein describes the hydrogeologic testing of the crystalline rocks and results of the work done by Gartner Lee AG (GLAG) in the Boettstein borehole on behalf of Nationale Genossenschaft Fuer Die Lagerung Radioaktiver Abfaelle (NAGRA). This report describes testing equipment and performance. Also included are sections on the testing and analysis methods that were used to determine the hydrogeologic results. Testing was conducted using single and double packer tools with associated down hole and surface electronic equipment. Down hole information from pressure transducers and thermistors were converted from frequency signals to pressure and temperature readings that were printed, plotted and stored on magnetic tape at the surface facility. All the testing equipment worked well. In summary, the hydrogeologic testing activities at the Boettstein borehole were successful in providing information for NAGRA's regional assessment of the crystalline basement rocks. In addition, water samples could be obtained from discrete intervals for geochemical characterization. Continuing ground water monitoring activities at this borehole will add to the data base provided by this report. (author)

  17. Rocks From Space: A Historical Perspective

    Science.gov (United States)

    Yeomans, Donald K.

    2013-10-01

    The notion that rocks could fall to Earth from space was not seriously considered until the early nineteenth century. The impact origin of the lunar craters reached a scientific consensus only in the mid twentieth century and a wide understanding that the Earth’s neighborhood is crowded with millions of near-Earth asteroids that could cause impact damage to Earth is less than a few decades old. In the late seventeenth century, even such notable scientists as Robert Hooke and Isaac Newton ruled out the existence of small bodies in space. In 1794, the German physicist and father of acoustics Ernst F.F. Chladni published a short list of fireball events and effectively argued that these events and the meteorites they dropped could not have been atmospheric and were likely due to cosmic rocks entering the Earth’s atmosphere. In 1802 the British chemist Edward Charles Howard showed that several meteoritic stones had similar chemical compositions and that nickel, which is seldom present in terrestrial rocks except in trace amounts, was common to all of them. These two pivotal works, along with a number of early nineteenth century falls, slowly strengthened the notion that fireball events and the stones they dropped were of celestial, rather than atmospheric, origin. Even so, it was well into the mid twentieth century before Meteor Crater in particular and the obvious lunar craters in general were widely considered as impact phenomena rather than being due to volcanic eruptions or steam generated explosions. It seems that despite Mother Nature’s best attempts to point out the importance of impact events in the solar system and the existence of a vast population of near-Earth asteroids, much of the scientific community reached these viewpoints rather late. Likely reasons for this slow acceptance of rocks from space will be discussed.

  18. Low Pore Connectivity in Natural Rock

    Energy Technology Data Exchange (ETDEWEB)

    Hu, Qinhong; Ewing, Robert P.; Dultz, Stefan

    2012-05-15

    As repositories for CO₂ and radioactive waste, as oil and gas reservoirs, and as contaminated sites needing remediation, rock formations play a central role in energy and environmental management. The connectivity of the rock's porespace strongly affects fluid flow and solute transport. This work examines pore connectivity and its implications for fluid flow and chemical transport. Three experimental approaches (imbibition, tracer concentration profiles, and imaging) were used in combination with network modeling. In the imbibition results, three types of imbibition slope [log (cumulative imbibition) vs. log (imbibition time)] were found: the classical 0.5, plus 0.26, and 0.26 transitioning to 0.5. The imbibition slope of 0.26 seen in Indiana sandstone, metagraywacke, and Barnett shale indicates low pore connectivity, in contrast to the slope of 0.5 seen in the well-connected Berea sandstone. In the tracer profile work, rocks exhibited different distances to the plateau porosity, consistent with the pore connectivity from the imbibition tests. Injection of a molten metal into connected pore spaces, followed by 2-D imaging of the solidified alloy in polished thin sections, allowed direct assessment of pore structure and lateral connection in the rock samples. Pore-scale network modeling gave results consistent with measurements, confirming pore connectivity as the underlying cause of both anomalous behaviors: imbibition slope not having the classical value of 0.5, and accessible porosity being a function of distance from the edge. A poorly connected porespace will exhibit anomalous behavior in fluid flow and chemical transport, such as a lower imbibition slope (in air–water system) and diffusion rate than expected from classical behavior.

  19. Low pore connectivity in natural rock.

    Science.gov (United States)

    Hu, Qinhong; Ewing, Robert P; Dultz, Stefan

    2012-05-15

    As repositories for CO(2) and radioactive waste, as oil and gas reservoirs, and as contaminated sites needing remediation, rock formations play a central role in energy and environmental management. The connectivity of the rock's porespace strongly affects fluid flow and solute transport. This work examines pore connectivity and its implications for fluid flow and chemical transport. Three experimental approaches (imbibition, tracer concentration profiles, and imaging) were used in combination with network modeling. In the imbibition results, three types of imbibition slope [log (cumulative imbibition) vs. log (imbibition time)] were found: the classical 0.5, plus 0.26, and 0.26 transitioning to 0.5. The imbibition slope of 0.26 seen in Indiana sandstone, metagraywacke, and Barnett shale indicates low pore connectivity, in contrast to the slope of 0.5 seen in the well-connected Berea sandstone. In the tracer profile work, rocks exhibited different distances to the plateau porosity, consistent with the pore connectivity from the imbibition tests. Injection of a molten metal into connected pore spaces, followed by 2-D imaging of the solidified alloy in polished thin sections, allowed direct assessment of pore structure and lateral connection in the rock samples. Pore-scale network modeling gave results consistent with measurements, confirming pore connectivity as the underlying cause of both anomalous behaviors: imbibition slope not having the classical value of 0.5, and accessible porosity being a function of distance from the edge. A poorly connected porespace will exhibit anomalous behavior in fluid flow and chemical transport, such as a lower imbibition slope (in air-water system) and diffusion rate than expected from classical behavior.

  20. A new method to test rock abrasiveness based on physico-mechanical and structural properties of rocks

    Institute of Scientific and Technical Information of China (English)

    V.N. Oparin; A.S. Tanaino

    2015-01-01

    abstract A new method to test rock abrasiveness is proposed based upon the dependence of rock abrasiveness on their structural and physico-mechanical properties. The article describes the procedure of presentation of properties that govern rock abrasiveness on a canonical scale by dimensionless components, and the integrated estimation of the properties by a generalized index. The obtained results are compared with the known classifications of rock abrasiveness.

  1. Thermal conductivity of the rocks in the Bureau of Mines Standard Rock Suite

    International Nuclear Information System (INIS)

    Thermal conductivities of eight rocks from the Bureau of Mines Standard Rock Suite were measured in air over the temperature range 373 to 5330K (100 to 2600C). The thermal conductivities of these rocks were measured to furnish standards for future comparisons with host rock from prospective nuclear waste repository sites. The thermal conductivity at a given temperature decreased by as much as 9% after a specimen had been heated to the maximum temperature (5330K), but additional heating cycles had no further effect. This decrease was smallest in the igneous rocks and largest in the sedimentary types. Variations due to orientation were within the precision of measurements (+- 5%). In most cases the thermal conductivities were linear with the reciprocal of the temperature and were within 14% of published data obtained by other methods. Measurements were made by a cut-bar comparison method in which the sample was sandwiched between two reference or metering bars made of Pyroceram 9606 glass-ceramic. The apparatus consisted of a Dynatech Model TCFCM-N20 comparative thermal conductivity analyzer controlled by a Hewlett Packard Model 3052A data acquisition system. A program was written to increment and cycle the temperature in steps between predetermined initial and maximum values. At each step the thermal conductivity was measured after steady-state conditions were established. The rocks furnished by the Bureau of Mines were quarried in large and fairly homogeneous lots for use by researchers at various laboratories. To investigate any anisotropy, cores were taken from each rock cube perpendicular to each of the cube faces. Samples 2 in. in diameter and approx. 0.75 in. thick were prepared from the cores and were dried in a vacuum oven for at least one month prior to taking measurements

  2. Flow and Transport Through Unsaturated Fractured Rock

    Science.gov (United States)

    Evans, Daniel D.; Nicholson, Thomas J.; Rasmussen, Todd C.

    This monograph is an update and revision of the first edition, Geophysical Monograph 42, on ground-water flow and transport through unsaturated, fractured rock, published by AGU in 1987. The first edition evolved from a special symposium held during the American Geophysical Union fall meetings in San Francisco in December 1986. Invited and contributed papers at that AGU session, as well as panel presentations, focused on conceptualizing, measuring and modeling flow and transport through unsaturated fractured rock. As noted in the preface to the first edition, "the expanded interest in the topic (water flow and contaminant transport through unsaturated fractured rock) was initiated when the U.S. Geological Survey proposed that deep unsaturated zones in arid regions be considered in the site selection for the first high-level, commercially generated radioactive waste repository." Much of the research reported in that first edition was motivated by the U.S. Department of Energy's program to investigate Yucca Mountain at the Nevada Test Site as a possible geologic repository for commercially generated, high-level radioactive waste. As noted in the overview paper of the first edition, "characterization methods and modeling are in their developmental stage with the greatest lack of knowledge being the interaction between fracture and matrix flow and transport properties." Although the first edition of this monograph reflected the state-of-the science, laboratory and field experimental programs were novel and limited and, in general, followed from the principles and methods developed in the soil science community.

  3. Aespoe Hard Rock Laboratory Annual report 2003

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-09-01

    The Aespoe Hard Rock Laboratory (HRL) constitutes an important part of SKB's work to design and construct a deep geological repository for spent nuclear fuel and to develop and test methods for characterisation of a suitable site for a deep repository. One of the fundamental reasons behind SKB's decision to construct an underground laboratory was to create an opportunity for research, development and demonstration in a realistic and undisturbed rock environment down to repository depth. Aespoe HRL has been in operation since 1995 and the associated research, development, and demonstration tasks, have so far attracted considerable interest. A summary of work performed at Aespoe HRL during 2003 is given below. Seven organisations from six countries participated in the co-operation at Aespoe HRL during 2003 in addition to SKB. Most of the organisations are interested in groundwater flow, radionuclide transport and rock characterisation. Several of the organisations are participating in the experimental work as well as in the Aespoe Task Force on Modelling of Groundwater Flow and Transport of Solutes. SKB is through Repository Technology co-ordinating three EC contracts and takes part in several EC projects of which the representation in five projects is channelled through Repository Technology. SKB takes also part in work within the IAEA framework.

  4. Hot Dry Rock Geothermal Energy Development Program

    Energy Technology Data Exchange (ETDEWEB)

    Smith, M.C.; Hendron, R.H.; Murphy, H.D.; Wilson, M.G.

    1989-12-01

    During Fiscal Year 1987, emphasis in the Hot Dry Rock Geothermal Energy Development Program was on preparations for a Long-Term Flow Test'' of the Phase II'' or Engineering'' hot dry rock energy system at Fenton Hill, New Mexico. A successful 30-day flow test of the system during FY86 indicated that such a system would produce heat at a temperature and rate that could support operation of a commercial electrical power plant. However, it did not answer certain questions basic to the economics of long-term operation, including the rate of depletion of the thermal reservoir, the rate of water loss from the system, and the possibility of operating problems during extended continuous operation. Preparations for a one-year flow test of the system to answer these and more fundamental questions concerning hot dry rock systems were made in FY87: design of the required surface facilities; procurement and installation of some of their components; development and testing of slimline logging tools for use through small-diameter production tubing; research on temperature-sensitive reactive chemical tracers to monitor thermal depletion of the reservoir; and computer simulations of the 30-day test, extended to modeling the planned Long-Term Flow Test. 45 refs., 34 figs., 5 tabs.

  5. Rock bed thermal storage: Concepts and costs

    Science.gov (United States)

    Allen, Kenneth; von Backström, Theodor; Joubert, Eugene; Gauché, Paul

    2016-05-01

    Thermal storage enables concentrating solar power (CSP) plants to provide baseload or dispatchable power. Currently CSP plants use two-tank molten salt thermal storage, with estimated capital costs of about 22-30 /kWhth. In the interests of reducing CSP costs, alternative storage concepts have been proposed. In particular, packed rock beds with air as the heat transfer fluid offer the potential of lower cost storage because of the low cost and abundance of rock. Two rock bed storage concepts which have been formulated for use at temperatures up to at least 600 °C are presented and a brief analysis and cost estimate is given. The cost estimate shows that both concepts are capable of capital costs less than 15 /kWhth at scales larger than 1000 MWhth. Depending on the design and the costs of scaling containment, capital costs as low as 5-8 /kWhth may be possible. These costs are between a half and a third of current molten salt costs.

  6. Aespoe Hard Rock Laboratory. Annual Report 2006

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-06-15

    The Aespoe Hard Rock Laboratory (HRL) is an important part of SKB's work with the design and construction of a deep geological repository for the final disposal of spent nuclear fuel. Aespoe HRL is located in the Simpevarp area in the municipality of Oskarshamn. One of the fundamental reasons behind SKB's decision to construct an underground laboratory was to create opportunities for research, development and demonstration in a realistic and undisturbed rock environment down to repository depth. The underground part of the laboratory consists of a tunnel from the Simpevarp peninsula to the southern part of Aespoe where the tunnel continues in a spiral down to a depth of 460 m. Aespoe HRL has been in operation since 1995 and considerable international interest has been shown in its research, as well as in the development and demonstration tasks. The work performed at Aespoe HRL during 2006 is in this report described in six chapters: Geo-science - experiments, analysis and modelling to increase the knowledge of the surrounding rock; Natural barriers - experiments, analysis and modelling to increase the knowledge of the repository barriers under natural conditions; Engineered barriers - demonstration of technology for and function of important engineered parts of the repository barrier system; Aespoe facility - operation, maintenance, data management, monitoring, public relations etc; Environmental research; and finally, International co-operation.

  7. Aespoe Hard Rock Laboratory. Annual Report 2006

    International Nuclear Information System (INIS)

    The Aespoe Hard Rock Laboratory (HRL) is an important part of SKB's work with the design and construction of a deep geological repository for the final disposal of spent nuclear fuel. Aespoe HRL is located in the Simpevarp area in the municipality of Oskarshamn. One of the fundamental reasons behind SKB's decision to construct an underground laboratory was to create opportunities for research, development and demonstration in a realistic and undisturbed rock environment down to repository depth. The underground part of the laboratory consists of a tunnel from the Simpevarp peninsula to the southern part of Aespoe where the tunnel continues in a spiral down to a depth of 460 m. Aespoe HRL has been in operation since 1995 and considerable international interest has been shown in its research, as well as in the development and demonstration tasks. The work performed at Aespoe HRL during 2006 is in this report described in six chapters: Geo-science - experiments, analysis and modelling to increase the knowledge of the surrounding rock; Natural barriers - experiments, analysis and modelling to increase the knowledge of the repository barriers under natural conditions; Engineered barriers - demonstration of technology for and function of important engineered parts of the repository barrier system; Aespoe facility - operation, maintenance, data management, monitoring, public relations etc; Environmental research; and finally, International co-operation

  8. Volcanic Rocks As Targets For Astrobiology Missions

    Science.gov (United States)

    Banerjee, N.

    2010-12-01

    Almost two decades of study highlight the importance of terrestrial subaqueous volcanic rocks as microbial habitats, particularly in glass produced by the quenching of basaltic lava upon contact with water. On Earth, microbes rapidly begin colonizing glassy surfaces along fractures and cracks exposed to water. Microbial colonization of basaltic glass leads to enhanced alteration through production of characteristic granular and/or tubular bioalteration textures. Infilling of formerly hollow alteration textures by minerals enable their preservation through geologic time. Basaltic rocks are a major component of the Martian crust and are widespread on other solar system bodies. A variety of lines of evidence strongly suggest the long-term existence of abundant liquid water on ancient Mars. Recent orbiter, lander and rover missions have found evidence for the presence of transient liquid water on Mars, perhaps persisting to the present day. Many other solar system bodies, notably Europa, Enceladus and other icy satellites, may contain (or have once hosted) subaqueous basaltic glasses. The record of terrestrial glass bioalteration has been interpreted to extend back ~3.5 billion years and is widespread in modern oceanic crust and its ancient metamorphic equivalents. The terrestrial record of glass bioalteration strongly suggests that glassy or formerly glassy basaltic rocks on extraterrestrial bodies that have interacted with liquid water are high-value targets for astrobiological exploration.

  9. No Reprieve for Tasmanian Rock Art

    Directory of Open Access Journals (Sweden)

    Peter C. Sims

    2013-10-01

    Full Text Available The Australian State of Tasmania, at latitude 42 degrees south, became an island about 8,000 years ago when the sea rose to its present level, following the melting of polar and glacial ice that covered much of the land mass. After that time, the Tasmanian Aboriginal rock art developed independently of mainland Australia, with its form being basically linear with some naturalistic figures and a predominance of cupules. The petroglyphs with one lithophone site occur on various rock substrates varying in hardness from granite to sandstone. Many sites exist along the western coastline that borders the Southern Ocean where the landscape in some places has changed little since the arrival of Europeans in 1803. The significance of this Tasmanian Aboriginal cultural heritage along what is now known as the Tarkine Coast, named after an Aboriginal band that once inhabited this area, was recognised by the Australian Government in February 2013 when a 21,000 ha strip, 2 km wide, was inscribed on its National Heritage Register, being one of 98 special places listed in the country. However, politics and racism hamper its management. This paper is based on the results of 40 years of field recording of the Tasmanian Aboriginal rock art sites, many of which remain unpublished.

  10. Rheological characteristics of soft rock structural surface

    Institute of Scientific and Technical Information of China (English)

    陈沅江; 吴超; 傅衣铭

    2008-01-01

    There are two mechanisms of the coarse surface asperity resistance effect and rubbing resistance effect in the course of the soft rock structural surface creep,of which the former plays a dominant role in hindering the deformation in the starting creep phase,so that the structural surface creep usually displays the strong surface roughness effect,and so does the latter when the asperities in the coarse surface were fractured by shearing.Under the low stress condition,there are only two phases of the decelerating creep and the constant creep for the soft rock structural surface,and as the stress increases and overcomes the rubbing resistance,the accelerating creep failure of the structural surface will happen suddenly.Therefore,a multiple rheological model,which combines the nonlinear NEWTON body(NN) of a certain mass and the empirical plastic body(EM) with the classical SAINT VENANT body,NEWTON body,KELVIN body and HOOKE body,could be used to comprehensively describe the creep characteristics of the soft rock structural surface.Its mechanical parameter values will vary owing to the different surface roughness of the structural surface.The parameters of GH,GK and ηL are positively linearly correlative to the surface roughness.The surface roughness and m are negative exponential function correlation.The long-term strength τS is positively correlative to the surface roughness.

  11. CERN’s Summer of Rock

    CERN Document Server

    Katarina Anthony

    2015-01-01

    When a rock star visits CERN, they don’t just bring their entourage with them. Along for the ride are legions of fans across the world – many of whom may not be the typical CERN audience. In July alone, four big acts paid CERN a visit, sharing their experience with the world: Scorpions, The Script, Kings of Leon and Patti Smith.   @TheScript tweeted: #paleofestival we had the best time! Big love. #CERN (Image: Twitter).   It all started with the Scorpions, the classic rock band whose “Wind of Change” became an anthem in the early 1990s. On 19 July, the band braved the 35-degree heat to tour the CERN site on foot – visiting the Synchrocyclotron and the new Microcosm exhibition. The rockers were very enthusiastic about the research carried out at CERN, and talked about returning in the autumn during their next tour stop. The Scorpions visit Microcosm. Two days later, The Script rolled in. This Irish pop-rock band has been hittin...

  12. Aespoe Hard Rock Laboratory Annual report 2003

    International Nuclear Information System (INIS)

    The Aespoe Hard Rock Laboratory (HRL) constitutes an important part of SKB's work to design and construct a deep geological repository for spent nuclear fuel and to develop and test methods for characterisation of a suitable site for a deep repository. One of the fundamental reasons behind SKB's decision to construct an underground laboratory was to create an opportunity for research, development and demonstration in a realistic and undisturbed rock environment down to repository depth. Aespoe HRL has been in operation since 1995 and the associated research, development, and demonstration tasks, have so far attracted considerable interest. A summary of work performed at Aespoe HRL during 2003 is given below. Seven organisations from six countries participated in the co-operation at Aespoe HRL during 2003 in addition to SKB. Most of the organisations are interested in groundwater flow, radionuclide transport and rock characterisation. Several of the organisations are participating in the experimental work as well as in the Aespoe Task Force on Modelling of Groundwater Flow and Transport of Solutes. SKB is through Repository Technology co-ordinating three EC contracts and takes part in several EC projects of which the representation in five projects is channelled through Repository Technology. SKB takes also part in work within the IAEA framework

  13. Halophilic archaea cultivated from surface sterilized middle-late eocene rock salt are polyploid.

    Directory of Open Access Journals (Sweden)

    Salla T Jaakkola

    Full Text Available Live bacteria and archaea have been isolated from several rock salt deposits of up to hundreds of millions of years of age from all around the world. A key factor affecting their longevity is the ability to keep their genomic DNA intact, for which efficient repair mechanisms are needed. Polyploid microbes are known to have an increased resistance towards mutations and DNA damage, and it has been suggested that microbes from deeply buried rock salt would carry several copies of their genomes. Here, cultivable halophilic microbes were isolated from a surface sterilized middle-late Eocene (38-41 million years ago rock salt sample, drilled from the depth of 800 m at Yunying salt mine, China. Eight unique isolates were obtained, which represented two haloarchaeal genera, Halobacterium and Halolamina. We used real-time PCR to show that our isolates are polyploid, with genome copy numbers of 11-14 genomes per cell in exponential growth phase. The ploidy level was slightly downregulated in stationary growth phase, but the cells still had an average genome copy number of 6-8. The polyploidy of halophilic archaea living in ancient rock salt might be a factor explaining how these organisms are able to overcome the challenge of prolonged survival during their entombment.

  14. Epigenetic repression of ribosomal RNA transcription by ROCK-dependent aberrant cytoskeletal organization

    Science.gov (United States)

    Wu, Tse-Hsiang; Kuo, Yuan-Yeh; Lee, Hsiao-Hui; Kuo, Jean-Cheng; Ou, Meng-Hsin; Chang, Zee-Fen

    2016-01-01

    It is known that ribosomal RNA (rRNA) synthesis is regulated by cellular energy and proliferation status. In this study, we investigated rRNA gene transcription in response to cytoskeletal stress. Our data revealed that the cell shape constrained by isotropic but not elongated micropatterns in HeLa cells led to a significant reduction in rRNA transcription dependent on ROCK. Expression of a dominant-active form of ROCK also repressed rRNA transcription. Isotropic constraint and ROCK over-activation led to different types of aberrant F-actin organization, but their suppression effects on rRNA transcription were similarly reversed by inhibition of histone deacetylase (HDAC) or overexpression of a dominant negative form of Nesprin, which shields the signal transmitted from actin filament to the nuclear interior. We further showed that the binding of HDAC1 to the active fraction of rDNA genes is increased by ROCK over-activation, thus reducing H3K9/14 acetylation and suppressing transcription. Our results demonstrate an epigenetic control of active rDNA genes that represses rRNA transcription in response to the cytoskeletal stress. PMID:27350000

  15. Retraction statement: 'Formin-like2 regulates Rho/ROCK pathway to promote actin assembly and cell invasion of colorectal cancer' by Yuanfeng Zeng, Huijun Xie, Yudan Qiao, Jianmei Wang, Xiling Zhu, Guoyang He, Yuling Li, Xiaoli Ren, Feifei Wang, Li Liang and Yanqing Ding.

    Science.gov (United States)

    2016-07-01

    The above article in Cancer Science (doi: 10.1111/cas.12768), published online on 26 October 2015 in Wiley Online Library (http://wileyonlinelibrary.com), has been retracted by agreement between the authors, the journal Editor in Chief, Yusuke Nakamura, and Wiley Publishing Asia Pty Ltd. The retraction has been agreed as Panels +C3 and +Y27632 of SW480 Mock shown in Figure 2a appear to have been taken from the same image, Panels + C3 and +Y27632 of HT29 FMNL2 shown in Figure 2a appear to have been taken from the same image, Panels shFMNL2-1 and shmDial1-1 in Figure 3a appear to have been taken from the same image, shFMNL2-2 and shmDial1-2 in Figure 3a appear to have been taken from the same image, Panels of shFMNL2-1 + shmDial1-1 and shFMNL2-1 + shmDial1-2 of +LPA appear to have been taken from the same image, gel bands of FLAG in Figure 4e appear to have been have been manipulated by erasing gel bands. Reference Zeng Y, Xie H, Qiao Y, Wang J, Zhu X, He G, Li Y, Ren X, Wang F, Liang L, Ding Y. Formin-like2 regulates Rho/ROCK pathway to promote actin assembly and cell invasion of colorectal cancer. Cancer Sci 2015; 106: 1385-93. doi: 10.1111/cas.12768.

  16. Retraction statement: ‘Formin‐like2 regulates Rho/ROCK pathway to promote actin assembly and cell invasion of colorectal cancer’ by Yuanfeng Zeng, Huijun Xie, Yudan Qiao, Jianmei Wang, Xiling Zhu, Guoyang He, Yuling Li, Xiaoli Ren, Feifei Wang, Li Liang and Yanqing Ding

    Science.gov (United States)

    2016-01-01

    The above article in Cancer Science (doi: 10.1111/cas.12768), published online on 26 October 2015 in Wiley Online Library (http://wileyonlinelibrary.com), has been retracted by agreement between the authors, the journal Editor in Chief, Yusuke Nakamura, and Wiley Publishing Asia Pty Ltd. The retraction has been agreed as Panels +C3 and +Y27632 of SW480 Mock shown in Figure 2a appear to have been taken from the same image, Panels + C3 and +Y27632 of HT29 FMNL2 shown in Figure 2a appear to have been taken from the same image, Panels shFMNL2‐1 and shmDial1‐1 in Figure 3a appear to have been taken from the same image, shFMNL2‐2 and shmDial1‐2 in Figure 3a appear to have been taken from the same image, Panels of shFMNL2‐1 + shmDial1‐1 and shFMNL2‐1 + shmDial1‐2 of +LPA appear to have been taken from the same image, gel bands of FLAG in Figure 4e appear to have been have been manipulated by erasing gel bands. Reference ZengY , XieH , QiaoY , WangJ , ZhuX , HeG , LiY , RenX , WangF , LiangL , DingY . Formin‐like2 regulates Rho/ROCK pathway to promote actin assembly and cell invasion of colorectal cancer. Cancer Sci 2015; 106: 1385–93. doi: 10.1111/cas.12768 26258642 PMID:27420476

  17. Retraction statement: 'Formin-like2 regulates Rho/ROCK pathway to promote actin assembly and cell invasion of colorectal cancer' by Yuanfeng Zeng, Huijun Xie, Yudan Qiao, Jianmei Wang, Xiling Zhu, Guoyang He, Yuling Li, Xiaoli Ren, Feifei Wang, Li Liang and Yanqing Ding.

    Science.gov (United States)

    2016-07-01

    The above article in Cancer Science (doi: 10.1111/cas.12768), published online on 26 October 2015 in Wiley Online Library (http://wileyonlinelibrary.com), has been retracted by agreement between the authors, the journal Editor in Chief, Yusuke Nakamura, and Wiley Publishing Asia Pty Ltd. The retraction has been agreed as Panels +C3 and +Y27632 of SW480 Mock shown in Figure 2a appear to have been taken from the same image, Panels + C3 and +Y27632 of HT29 FMNL2 shown in Figure 2a appear to have been taken from the same image, Panels shFMNL2-1 and shmDial1-1 in Figure 3a appear to have been taken from the same image, shFMNL2-2 and shmDial1-2 in Figure 3a appear to have been taken from the same image, Panels of shFMNL2-1 + shmDial1-1 and shFMNL2-1 + shmDial1-2 of +LPA appear to have been taken from the same image, gel bands of FLAG in Figure 4e appear to have been have been manipulated by erasing gel bands. Reference Zeng Y, Xie H, Qiao Y, Wang J, Zhu X, He G, Li Y, Ren X, Wang F, Liang L, Ding Y. Formin-like2 regulates Rho/ROCK pathway to promote actin assembly and cell invasion of colorectal cancer. Cancer Sci 2015; 106: 1385-93. doi: 10.1111/cas.12768. PMID:27420476

  18. Search for magnetic minerals in Martian rocks: Overview of the Rock Abrasion Tool (RAT) magnet investigation on Spirit and Opportunity

    DEFF Research Database (Denmark)

    Goetz, W.; Leer, K.; Gunnlaugsson, H.P.;

    2008-01-01

    The Rock Abrasion Tool (RAT) on board the Mars Exploration Rovers (MER) is a grinding tool designed to remove dust coatings and/or weathering rinds from rocks and expose fresh rock material. Four magnets of different strengths that are built into the structure of the RAT have been attracting...

  19. 法舒地尔通过Rho-ROCK通路抑制高糖诱导的单核细胞与内皮细胞黏附%Fasudil Inhibiting High Glucose Induced Monocyte-Endothelial Cells Adhesion Through Rho/ROCK Pathway

    Institute of Scientific and Technical Information of China (English)

    李琦; 李海玲; 彭文辉; 徐亚伟

    2012-01-01

    Aim To investigate whether Rho kinase inhibitor fasudil inhibits high glucose ( HG) -induced cell adhesion to human umbilical vein endothelial cells (HUVEC) and search for its underlying mechanisms. Methods The adhesion of monocytes to HUVEC was determined using fluorescence-labeled monocytes. The mRNA and protein levels of vascular cell adhesion molecule-1 (VCAM-1) and monocyte chemotactic protein l(MCP-l) were measured using real-time polymerase chain reaction ( RT-PCR) and Western blot. The amounts of RhoA, R0CK1, p-MYPT and MYPT were determined using Western blot analysis. Results Fasudil significantly suppressed HG-induced adhesion of THP-1 to HUVEC in a dose manner; namely by about 33.4% in the presence of low dose (10~6 mmol/L) and by 42. 8% in high dose (10~5 mmol/L) at 24 hours (both P <0. 05) ; the same for 12 h. Fasudil significantly suppressed the HG-induced increase of mRNA and protein expression of VCAM-1 and MCP-1 in dose and time manner. HG markedly increased ratio of p-MYPT/MYPT, while fasudil inhibited HG-induced activation of Rho/ROCK pathway. Conclusion The adhesion of monocytes to HUVEC and the expression of VCAM-land MCP-1 induced by high glucose could be inhibited by fasudil,the same to activation of Rho/ROCK pathway. It suggests that fasudil may represent a new treatment for diabetic vascular injury.%目的 观察Rho激酶抑制剂法舒地尔能否抑制高糖诱导的单核细胞(THP-1)与人脐静脉内皮细胞黏附,初步探讨其潜在机制.方法 使用荧光显微镜观察荧光标记的THP-1与人脐静脉内皮细胞黏附.血管细胞黏附分子1和单核细胞趋化蛋白1的mRNA及蛋白表达水平分别通过RT-PCR、Western blot检测.使用Western blot 检测RhoA、ROCK-1、p-MYPT及MYPT蛋白表达水平变化.结果 法舒地尔显著抑制高糖诱导的THP-1与人脐静脉内皮细胞黏附,并呈剂量依赖性,其中,低浓度法舒地尔( 10-6 mmol/L)干预24h黏附减少约33.4%,高浓度法舒地尔( 10-5 mmol

  20. Prediction of grout penetration in fractured rocks by numerical simulation

    OpenAIRE

    Yang, MJ; Yue, ZQ; Lee, PKK; Su, B; Tham, LG

    2002-01-01

    As fractures in rock significantly reduce the strength as well as the stiffness of the rock mass, grouting may be required to improve the performance of the rock mass in engineering or mining projects. During grouting, mortar of cement or other materials is injected into the rock mass so that the fractures can be filled up and the rock mass can act as an integral unit. Unlike water, grouts are usually viscous and behave as non-Newtonian fluids. Therefore, the equations describing the flow of ...

  1. Robotic Instrument for Grinding Rocks Into Thin Sections (GRITS)

    Science.gov (United States)

    Paulsen, Gale; Zacny, Kris; Dreyer, Christopher B.; Szucs, Attila; Szczesiak, Matt; Santoro, Chris; Craft, Jack; Hedlund, Magnus; Skok, John

    2013-06-01

    We have developed a rock grinding and polishing mechanism for in situ planetary exploration based on abrasive disks, called Grinding Rocks Into Thin Sections (GRITS). Performance characteristics and design considerations of GRITS are presented. GRITS was developed as part of a broader effort to develop an in situ automated rock thin section (ISARTS) instrument. The objective of IS-ARTS was to develop an instrument capable of producing petrographic rock thin sections on a planetary science spacecraft. GRITS may also be useful to other planetary science missions with in situ instruments in which rock surface preparation are necessary.

  2. Basaltic rocks analyzed by the Spirit Rover in Gusev Crater

    Science.gov (United States)

    McSween, H. Y.; Arvidson, R. E.; Bell, J. F., III; Blaney, D.; Cabrol, N. A.; Christensen, P. R.; Clark, B. C.; Crisp, J. A.; Crumpler, L. S.; DesMarais, D. J.; Farmer, J. D.; Gellert, R.; Ghosh, A.; Gorevan, S.; Graff, T.; Grant, J.; Haskin, L. A.; Herkenhoff, K. E.; Johnson, J. R.; Jolliff, B. L.; Klingelhoefer, G.; Morris, R. V.; Yen, A.

    2004-01-01

    The Spirit landing site in Gusev Crater on Mars contains dark, fine-grained, vesicular rocks interpreted as lavas. Pancam and Mini-Thermal Emission Spectrometer (Mini-TES) spectra suggest that all of these rocks are similar but have variable coatings and dust mantles. Magnified images of brushed and abraded rock surfaces show alteration rinds and veins. Rock interiors contain Particle X-ray Spectrometer are consistent with picritic basalts, containing normative olivine, pyroxenes, plagioclase, and accessory FeTi oxides. Mossbauer, Pancam, and Mini-TES spectra confirm the presence of olivine, magnetite, and probably pyroxene. These basalts extend the known range of rock compositions composing the martian crust.

  3. Rock Burst Mechanics: Insight from Physical and Mathematical Modelling

    OpenAIRE

    Vacek, J.; J. Chocholoušová

    2008-01-01

    Rock burst processes in mines are studied by many groups active in the field of geomechanics. Physical and mathematical modelling can be used to better understand the phenomena and mechanisms involved in the bursts. In the present paper we describe both physical and mathematical models of a rock burst occurring in a gallery of a coal mine.For rock bursts (also called bumps) to occur, the rock has to possess certain particular rock burst properties leading to accumulation of energy and the pot...

  4. Selected references on alkalic igneous rocks of the United States

    Energy Technology Data Exchange (ETDEWEB)

    Hall, C.R. (comp.)

    1976-01-01

    A compilation of references is presented providing background information on rock and mineral associations, geochemistry, geophysics, structural relationships, and geochronology of sialic, feldspathoidal, and some mafic alkalic igneous rock exposures in the US. Their locations and major characteristics are cited. No implication regarding U potential in these areas is intended. The first part of the bibliography provides general references to overall features of alkaline igneous rocks by region. The second part is a compilation of references on alkalic igneous rocks by state or groups of states. The third part provides information on rock type, age, and location for most of the references cited in part two. (JSR)

  5. Properties of Flow Zones in Fractured Rock

    Science.gov (United States)

    Salve, R.

    2004-12-01

    Observations over the last 25 years from various field studies suggest that preferential flow is common in soils and rocks. Despite this realization, very little is known about the large-scale properties (e.g., structure, distribution, continuity) of such flow regimes. This information is important for predictive models, but it remains elusive, mainly because of the difficulties involved in characterizing flow that has substantial spatial (both vertical and horizontal) and temporal variability. To better understand preferential flow in fractured rock, we carried out an in situ field experiment in the Topopah Spring tuff found in Exploratory Studies Facility at Yucca Mountain, Nevada. This experiment involved the release of ~22 m3 of ponded water (at a pressure head of ~0.04 m) over a period of 7 months, directly onto a 12 m2 infiltration plot. As water was released, changes in moisture content were monitored along horizontal boreholes located in the formation ~19-22 m below. Distinct flow zones, with significant differences in flow velocity, size, and extent of lateral movement, intercepted the 6-9 m long monitoring boreholes. Further, in some flow zones saturation levels persisted for the time period in which water was released, while in others there were periodic fluctuations. There was also evidence of water being diverted above the ceiling of a cavity in the immediate vicinity of the monitoring boreholes. Observations from this field experiment suggested that inconsistencies exist in present conceptual models of flow in fractured rock. Particularly, these observations suggest that isolated conduits within the fractured rock formation encompass a large number of fractures to form preferential flow paths that persist if there is a continuous supply of water. It appears that in fractured welded tuffs, the propensity for vertical dispersion and fracture-matrix interactions may be significantly greater than suggested by existing conceptual models. These observations

  6. Aespoe Hard Rock Laboratory. Annual report 1997

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-05-01

    The Aespoe Hard Rock Laboratory has been constructed as part of the preparations for the deep geological repository for spent nuclear fuel in Sweden. The surface and borehole investigations and the research work performed in parallel with construction have provided a thorough test of methods for investigation and evaluation of bedrock conditions for construction of a deep repository. The Tracer Retention Understanding Experiments are made to gain a better understanding of radionuclide retention in the rock and create confidence in the radionuclide transport models that are intended to be used in the licensing of a deep repository for spent fuel. The experimental results of the first tracer test with sorbing radioactive tracers have been obtained. These tests have been subject to blind predictions by the Aespoe Task Force on groundwater flow and transports of solutes. The manufacturing of the CHEMLAB probe was completed during 1996, and the first experiments were started early in 1997. During 1997 three experiments on diffusion in bentonite using {sup 57}Co, {sup 114}Cs,{sup 85}Sr, {sup 99}Tc, and {sup 131}I were conducted. The Prototype Repository Test is focused on testing and demonstrating repository system function. A full scale prototype including six deposition holes with canisters with electric heaters surrounded by highly compacted bentonite will be built and instrumented. The characterization of the rock mass in the area of the prototype repository is in progress. The objectives of the Demonstration of Repository Technology are to develop, test, and demonstrate methodology and equipment for encapsulation and deposition of spent nuclear fuel. The demonstration of handling and deposition will be made in a new drift. The Backfill and Plug Test includes tests of backfill materials and emplacement methods and a test of a full scale plug. The backfill and rock will be instrumented with about 230 transducers for measuring the thermo-hydro-mechanical processes. The

  7. Aespoe Hard Rock Laboratory. Annual report 1997

    International Nuclear Information System (INIS)

    The Aespoe Hard Rock Laboratory has been constructed as part of the preparations for the deep geological repository for spent nuclear fuel in Sweden. The surface and borehole investigations and the research work performed in parallel with construction have provided a thorough test of methods for investigation and evaluation of bedrock conditions for construction of a deep repository. The Tracer Retention Understanding Experiments are made to gain a better understanding of radionuclide retention in the rock and create confidence in the radionuclide transport models that are intended to be used in the licensing of a deep repository for spent fuel. The experimental results of the first tracer test with sorbing radioactive tracers have been obtained. These tests have been subject to blind predictions by the Aespoe Task Force on groundwater flow and transports of solutes. The manufacturing of the CHEMLAB probe was completed during 1996, and the first experiments were started early in 1997. During 1997 three experiments on diffusion in bentonite using 57Co, 114Cs,85Sr, 99Tc, and 131I were conducted. The Prototype Repository Test is focused on testing and demonstrating repository system function. A full scale prototype including six deposition holes with canisters with electric heaters surrounded by highly compacted bentonite will be built and instrumented. The characterization of the rock mass in the area of the prototype repository is in progress. The objectives of the Demonstration of Repository Technology are to develop, test, and demonstrate methodology and equipment for encapsulation and deposition of spent nuclear fuel. The demonstration of handling and deposition will be made in a new drift. The Backfill and Plug Test includes tests of backfill materials and emplacement methods and a test of a full scale plug. The backfill and rock will be instrumented with about 230 transducers for measuring the thermo-hydro-mechanical processes. The Retrieval Test is aiming at

  8. Chaotic time series prediction for surrounding rock's deformation of deep mine lanes in soft rock

    Institute of Scientific and Technical Information of China (English)

    LI Xi-bing; WANG Qi-sheng; YAO Jin-rui; ZHAO Guo-yan

    2008-01-01

    Based on the measured displacements, the change laws of the effect of distance in phase space on the deformation of mine lane were analyzed and the chaotic time series model to predict the surrounding rocks deformation of deep mine lane in soft rock by nonlinear theory and methods was established. The chaotic attractor dimension(D) and the largest Lyapunov index(Emax) were put forward to determine whether the deformation process of mine lane is chaotic and the degree of chaos. The analysis of examples indicates that when D>2 and Emax>0, the surrounding rock's deformation of deep mine lane in soft rock is the chaotic process and the laws of the deformation can still be well demonstrated by the method of the reconstructive state space. Comparing with the prediction of linear time series and grey prediction, the chaotic time series prediction has higher accuracy and the prediction results can provide theoretical basis for reasonable support of mine lane in soft rock. The time of the second support in Maluping Mine of Guizhou, China, is determined to arrange at about 40 d after the initial support according to the prediction results.

  9. ROCK PROPERTIES MODEL ANALYSIS MODEL REPORT

    Energy Technology Data Exchange (ETDEWEB)

    Clinton Lum

    2002-02-04

    The purpose of this Analysis and Model Report (AMR) is to document Rock Properties Model (RPM) 3.1 with regard to input data, model methods, assumptions, uncertainties and limitations of model results, and qualification status of the model. The report also documents the differences between the current and previous versions and validation of the model. The rock properties models are intended principally for use as input to numerical physical-process modeling, such as of ground-water flow and/or radionuclide transport. The constraints, caveats, and limitations associated with this model are discussed in the appropriate text sections that follow. This work was conducted in accordance with the following planning documents: WA-0344, ''3-D Rock Properties Modeling for FY 1998'' (SNL 1997, WA-0358), ''3-D Rock Properties Modeling for FY 1999'' (SNL 1999), and the technical development plan, Rock Properties Model Version 3.1, (CRWMS M&O 1999c). The Interim Change Notice (ICNs), ICN 02 and ICN 03, of this AMR were prepared as part of activities being conducted under the Technical Work Plan, TWP-NBS-GS-000003, ''Technical Work Plan for the Integrated Site Model, Process Model Report, Revision 01'' (CRWMS M&O 2000b). The purpose of ICN 03 is to record changes in data input status due to data qualification and verification activities. These work plans describe the scope, objectives, tasks, methodology, and implementing procedures for model construction. The constraints, caveats, and limitations associated with this model are discussed in the appropriate text sections that follow. The work scope for this activity consists of the following: (1) Conversion of the input data (laboratory measured porosity data, x-ray diffraction mineralogy, petrophysical calculations of bound water, and petrophysical calculations of porosity) for each borehole into stratigraphic coordinates; (2) Re-sampling and merging of data sets; (3

  10. Rock shape, restitution coefficients and rockfall trajectory modelling

    Science.gov (United States)

    Glover, James; Christen, Marc; Bühler, Yves; Bartelt, Perry

    2014-05-01

    Restitution coefficients are used in rockfall trajectory modelling to describe the ratio between incident and rebound velocities during ground impact. They are central to the problem of rockfall hazard analysis as they link rock mass characteristics to terrain properties. Using laboratory experiments as a guide, we first show that restitution coefficients exhibit a wide range of scatter, although the material properties of the rock and ground are constant. This leads us to the conclusion that restitution coefficients are poor descriptors of rock-ground interaction. The primary problem is that "apparent" restitution coefficients are applied at the rock's centre-of-mass and do not account for rock shape. An accurate description of the rock-ground interaction requires the contact forces to be applied at the rock surface with consideration of the momentary rock position and spin. This leads to a variety of rock motions including bouncing, sliding, skipping and rolling. Depending on the impact configuration a wide range of motions is possible. This explains the large scatter of apparent restitution coefficients. We present a rockfall model based on newly developed hard-contact algorithms which includes the effects of rock shape and therefore is able to reproduce the results of different impact configurations. We simulate the laboratory experiments to show that it is possible to reproduce run-out and dispersion of different rock shapes using parameters obtained from independent tests. Although this is a step forward in rockfall trajectory modelling, the problem of parametersing real terrain remains.

  11. Characterization of Strength of Intact Brittle Rock Considering Confinement-Dependent Failure Processes

    Science.gov (United States)

    Kaiser, Peter K.; Kim, Bo-Hyun

    2015-01-01

    unconfined compression tests (UCS) alone, the confined strength may be underestimated by as much as 50 % (on average). If triaxial data with a limited confinement range (e.g., σ3 ≪ 0.5 UCS due to cell pressure limitations) are used, the confined strength may be overestimated. Therefore, the application of standard data fitting procedures, without consideration of confinement-dependent failure mechanisms, may lead to erroneous intact rock strength parameters when applied to brittle rocks, and consequently, by extrapolation, to correspondingly erroneous rock mass strength parameters. It follows that the strength characteristics of massive rock differ significantly in the direct vicinity of excavation from that which is remote with higher confinement. Therefore, it is recommended to adopt a differentiated approach to obtain intact rock strength parameters for engineering problems at lower confinement (near excavation; e.g., excavation stability assessment or support design), and at elevated confinement (typically, when the confinement exceeds about 10 % of the UCS) as might be encountered in wide pillar cores.

  12. Tautochrone and Brachistochrone Shape Solutions for Rocking Rigid Bodies

    CERN Document Server

    Glaschke, Patrick

    2016-01-01

    Rocking rigid bodies appear in several shapes in everyday life: As furniture like rocking chairs and rocking cradles or as toys like rocking horses or tilting dolls. The familiar rocking motion of these objects, a non-linear combination of a rigid rotation and a translation of the center of mass, gives rise to a number of interesting dynamical properties. However, their study has received little attention in the literature. This work presents a comprehensive introduction to the dynamics of rocking rigid bodies, including a concise derivation of the equations of motion as well as a general inversion procedure to construct rocking rigid body shapes with specified dynamical properties. Moreover, two novel rigid body shapes are derived - the tautochrone shape and the brachistochrone shape - which represent an intriguing generalization of the well-know tautochrone and brachistochrone curves. In particular, tautochrone shapes offer an alternative construction of a tautochrone pendulum, in addition to Huygens' cyclo...

  13. Rock stress measurements in ONKALO underground characterisation facility at Olkiluoto at depth of 120 m

    International Nuclear Information System (INIS)

    In November and December 2006 overcoring stress measurements have been conducted in the boreholes ONK-PP74, ONK-PP75 and ONK-PP77 in a niche of the access tunnel of the ONKALO underground characterisation facility at the Olkiluoto site. Measurements have been done using the CSIRO 3D stress measuring cell. This cell is one of the mostly used cells in the whole world for estimation of the state of stress in rock when doing the borehole measurements. The boreholes are at a depth of about 120 m under the ground surface. The rock where the measurements have been conducted is a foliated migmatitic gneiss (subtypes veined and diatexitic gneiss). Parallel to the overcoring measurements a glue test has been conducted in the laboratory to check the quality of the bonding of the stress cells to the rock. The result showed that the glue makes a good contact between the rock and the stress cell, but air bubbles, which have normally been observed within the glue and at the edges, proved this time to be disadvantageous. Normally such air bubbles have dimensions of about one millimetre, but sometimes certain bubbles may become notably bigger. In the ONKALO overcored probes sawn apart such air bubbles were found both in wet and dry probe conditions. In the test series eight stress measurements have been provided, three of them failed for technical reasons. At one of these three tests the glue has extruded too early, at the other two tests the overcoring was not conducted deep enough. At the remaining five tests in spite of the glue test results a calculation of the stress tensor could be made. Four of these five measurements can be seen as relatively successful. The results of these measurements show a major principal stress of 14.8 MPa in average, trending northwest - southeast, and with a dipping of 11 degrees in average. (orig.)

  14. Softening Substrates Promote Chondrocytes Phenotype via RhoA/ROCK Pathway.

    Science.gov (United States)

    Zhang, Tao; Gong, Tao; Xie, Jing; Lin, Shiyu; Liu, Yao; Zhou, Tengfei; Lin, Yunfeng

    2016-09-01

    Due to its evascular, aneural, and alymphatic conditions, articular cartilage shows extremely poor regenerative ability. Thus, directing chondrocyte toward a desired location and function by utilizing the mechanical cues of biomaterials is a promising approach for effective tissue regeneration. However, chondrocytes cultured on Petri dish will lose their typical phenotype which may lead to compromised results. Therefore, we fabricated polydimethylsiloxane (PDMS) materials with various stiffness as culture substrates. Cell morphology and focal adhesion of chondrocytes displayed significant changes. The cytoskeletal tension of the adherent cells observed by average myosin IIA fluorescent intensity increased as stiffness of the underlying substrates decreased, consistent with the alteration of chondrocyte phenotype in our study. Immunofluorescent images and q-PCR results revealed that chondrocyte cultured on soft substrates showed better chondrocyte functionalization by more type II collagen and aggrecan expression, related to the lowest mRNA level of Rac-1, RhoA, ROCK-1, and ROCK-2. Taken together, this work not only points out that matrix elasticity can regulate chondrocyte functionalization via RhoA/ROCK pathway, but also provides new prospect for biomechanical control of cell behavior in cell-based cartilage regeneration.

  15. Analysis profile of the fully grouted rock bolt in jointed rock using analytical and numerical methods

    Institute of Scientific and Technical Information of China (English)

    Ghadimi Mostafa; Shahriar Kourosh; Jalalifar Hossein

    2014-01-01

    The purpose of this study was to investigate the effect of bolt profile on load transfer mechanism of fully grouted bolts in jointed rocks using analytical and numerical methods. Based on the analytical method with development of methods, a new model is presented. To validate the analytical model, five different profiles modeled by ANSYS software. The profile of rock bolts T3 and T4 with load transfer capacity, respectively 180 and 195 kN in the jointed rocks was selected as the optimum profiles. Finally, the selected profiles were examined in Tabas Coal Mine. FLAC analysis indicates that patterns 6+7 with 2NO flexi bolt 4 m better than other patterns within the faulted zone.

  16. Radionuclide transport and retardation in rock fracture and crushed rock column experiments

    Science.gov (United States)

    Höltä, P.; Siitari-Kauppi, M.; Hakanen, M.; Huitti, T.; Hautojärvi, A.; Lindberg, A.

    1997-04-01

    Transport and retardation of non-sorbing tritiated water and chloride and slightly sorbing sodium was studied in Syyry area SY-KR7 mica gneiss, in altered porous tonalite and in fresh tonalite. Experiments were performed using dynamic fracture and crushed rock column methods. Static batch method for sodium was introduced to compare retardation values from static and dynamic experiments. The 14C-PMMA method was used to study the pore structure of matrices. The pore aperture distribution was evaluated from Hg-porosimetry determinations and the surface areas were determined using the B.E.T. method. The flow characteristics and transport behavior of tracers were interpreted using a numerical compartment model for dispersion. The effect of matrix diffusion was calculated using an analytical solution to the advection-matrix diffusion problem in which surface retardation was taken into account. Radionuclide transport behavior in rock fractures was explained on the basis of rock structure.

  17. Prediction of Fracture Behavior in Rock and Rock-like Materials Using Discrete Element Models

    Science.gov (United States)

    Katsaga, T.; Young, P.

    2009-05-01

    The study of fracture initiation and propagation in heterogeneous materials such as rock and rock-like materials are of principal interest in the field of rock mechanics and rock engineering. It is crucial to study and investigate failure prediction and safety measures in civil and mining structures. Our work offers a practical approach to predict fracture behaviour using discrete element models. In this approach, the microstructures of materials are presented through the combination of clusters of bonded particles with different inter-cluster particle and bond properties, and intra-cluster bond properties. The geometry of clusters is transferred from information available from thin sections, computed tomography (CT) images and other visual presentation of the modeled material using customized AutoCAD built-in dialog- based Visual Basic Application. Exact microstructures of the tested sample, including fractures, faults, inclusions and void spaces can be duplicated in the discrete element models. Although the microstructural fabrics of rocks and rock-like structures may have different scale, fracture formation and propagation through these materials are alike and will follow similar mechanics. Synthetic material provides an excellent condition for validating the modelling approaches, as fracture behaviours are known with the well-defined composite's properties. Calibration of the macro-properties of matrix material and inclusions (aggregates), were followed with the overall mechanical material responses calibration by adjusting the interfacial properties. The discrete element model predicted similar fracture propagation features and path as that of the real sample material. The path of the fractures and matrix-inclusion interaction was compared using computed tomography images. Initiation and fracture formation in the model and real material were compared using Acoustic Emission data. Analysing the temporal and spatial evolution of AE events, collected during the

  18. Extraction of whole versus ground source rocks: Fundamental petroleum geochemical implications including oil-source rock correlation

    Science.gov (United States)

    Price, L.C.; Clayton, J.L.

    1992-01-01

    In petroleum geochemistry, extractable hydrocarbons (HCs) in source rocks have typically been studied by grinding the rock to a fine powder (???100 mesh) and then extracting the HCs from the rock with a solvent. This procedure carries the implicit assumption that the HCs are homogeneously distributed throughout the rock. However, sequential Soxhlet extractions of whole (unpowdered) source rocks have shown that progressive extracts from the same rock can be quite different and may not even correlate with each other. A crude oil-like material clearly has been fractionated from indigenous bitumen in these rocks, has moved to cracks and parting laminae in the rocks, is ready for expulsion from the rocks, and is thus most accessible to the first extracting solvents. This process, which we believe is largely due to HC gases and carbon dioxide generated over all maturation ranks in source rocks, carries petroleum geochemical implications of a fundamental nature for oil-source rock correlations and gives insight into primary migration mechanisms, origin of oil deposits, and use of maturity and organic-facies indices. ?? 1992.

  19. Aespoe Hard Rock Laboratory. Annual report 1998

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-05-01

    The Aespoe Hard Rock Laboratory has been constructed as part of the preparations for the deep geological repository for spent nuclear fuel in Sweden. The Tracer Retention Understanding Experiments are made to gain a better understanding of radionuclide retention in the rock and create confidence in the radionuclide transport models that are intended to be used in the licensing of a deep repository for spent fuel. Experiments with sorbing radioactive tracers have been completed in a single fracture over a distance of about 5 m. These tests have been subject to blind predictions by the Aespoe Task Force on groundwater flow and transports of solutes. Breakthrough of sorbing tracers in the TRUE-I tests is retarded more strongly than would be expected based on laboratory data alone. Results are consistent for all tracers and tracer tests. The main objective of the TRUE Block Scale Experiment is to increase understanding and our ability to predict tracer transport in a fracture network over spatial scales of 10 to 50 m. The total duration of the project is approximately 4.5 years with a scheduled finish at the end of the year 2000. The REX project focuses on the reduction of oxygen in a repository after closure due to reactions with rock minerals and microbial activity. Results show that oxygen is consumed within a few days both for the field and laboratory experiments. The project Degassing of groundwater and two phase flow was initiated to improve our understanding of observations of hydraulic conditions made in drifts and interpretation of experiments performed close to drifts. The analysis performed so far shows that the experimentally observed flow reductions indeed are consistent with the degassing hypothesis. The Prototype Repository Test is focused on testing and demonstrating repository system function. A full-scale prototype including six deposition holes with canisters with electric heaters surrounded by highly compacted bentonite will be built and

  20. Aespoe Hard Rock Laboratory. Annual report 1998

    International Nuclear Information System (INIS)

    The Aespoe Hard Rock Laboratory has been constructed as part of the preparations for the deep geological repository for spent nuclear fuel in Sweden. The Tracer Retention Understanding Experiments are made to gain a better understanding of radionuclide retention in the rock and create confidence in the radionuclide transport models that are intended to be used in the licensing of a deep repository for spent fuel. Experiments with sorbing radioactive tracers have been completed in a single fracture over a distance of about 5 m. These tests have been subject to blind predictions by the Aespoe Task Force on groundwater flow and transports of solutes. Breakthrough of sorbing tracers in the TRUE-I tests is retarded more strongly than would be expected based on laboratory data alone. Results are consistent for all tracers and tracer tests. The main objective of the TRUE Block Scale Experiment is to increase understanding and our ability to predict tracer transport in a fracture network over spatial scales of 10 to 50 m. The total duration of the project is approximately 4.5 years with a scheduled finish at the end of the year 2000. The REX project focuses on the reduction of oxygen in a repository after closure due to reactions with rock minerals and microbial activity. Results show that oxygen is consumed within a few days both for the field and laboratory experiments. The project Degassing of groundwater and two phase flow was initiated to improve our understanding of observations of hydraulic conditions made in drifts and interpretation of experiments performed close to drifts. The analysis performed so far shows that the experimentally observed flow reductions indeed are consistent with the degassing hypothesis. The Prototype Repository Test is focused on testing and demonstrating repository system function. A full-scale prototype including six deposition holes with canisters with electric heaters surrounded by highly compacted bentonite will be built and