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Sample records for cell nuclei

  1. Release of cell-free ice nuclei by Erwinia herbicola.

    OpenAIRE

    Phelps, P; Giddings, T. H.; Prochoda, M; Fall, R

    1986-01-01

    Several ice-nucleating bacterial strains, including Erwinia herbicola, Pseudomonas fluorescens, and Pseudomonas syringae isolates, were examined for their ability to shed ice nuclei into the growth medium. Only E. herbicola isolates shed cell-free ice nuclei active at -2 to -10 degrees C. These cell-free nuclei exhibited a freezing spectrum similar to that of ice nuclei found on whole cells, both above and below -5 degrees C. Partially purified cell-free nuclei were examined by density gradie...

  2. Mapping eGFP Oligomer Mobility in Living Cell Nuclei

    OpenAIRE

    Nicolas Dross; Corentin Spriet; Monika Zwerger; Gabriele Müller; Waldemar Waldeck; Jörg Langowski

    2009-01-01

    Movement of particles in cell nuclei can be affected by viscosity, directed flows, active transport, or the presence of obstacles such as the chromatin network. Here we investigate whether the mobility of small fluorescent proteins is affected by the chromatin density. Diffusion of inert fluorescent proteins was studied in living cell nuclei using fluorescence correlation spectroscopy (FCS) with a two-color confocal scanning detection system. We first present experiments exposing FCS-specific...

  3. Chromatin factors affecting DNA repair in mammalian cell nuclei

    International Nuclear Information System (INIS)

    We are investigating chromatin factors that participate in the incision step of DNA repair in eukaryotic cells. Localization of repair activity within nuclei, the stability and extractability of activity, the specificity for recognizing damage in chromatin or purified DNA as substrates are of interest in this investigation of human cells, CHO cells, and their radiation sensitive mutants. We have developed procedures that provide nuclei in which their DNA behaves as a collection of circular molecules. The integrity of the DNA in human nuclei can be maintained during incubation in appropriate buffers for as long as 60 minutes. When cells or nuclei are exposed to uv light prior to incubation, incisions presumably associated with DNA repair can be demonstrated. Incision activity is stable to prior extraction of nuclei with 0.6 M NaCl, which removes many nonhistone proteins. Our studies are consistent with an hypothesis that factors responsible for initiating DNA repair are localized in the nuclear matrix. 18 references, 3 figures

  4. Vertical uniformity of cells and nuclei in epithelial monolayers.

    Science.gov (United States)

    Neelam, Srujana; Hayes, Peter Robert; Zhang, Qiao; Dickinson, Richard B; Lele, Tanmay P

    2016-01-01

    Morphological variability in cytoskeletal organization, organelle position and cell boundaries is a common feature of cultured cells. Remarkable uniformity and reproducibility in structure can be accomplished by providing cells with defined geometric cues. Cells in tissues can also self-organize in the absence of directing extracellular cues; however the mechanical principles for such self-organization are not understood. We report that unlike horizontal shapes, the vertical shapes of the cell and nucleus in the z-dimension are uniform in cells in cultured monolayers compared to isolated cells. Apical surfaces of cells and their nuclei in monolayers were flat and heights were uniform. In contrast, isolated cells, or cells with disrupted cell-cell adhesions had nuclei with curved apical surfaces and variable heights. Isolated cells cultured within micron-sized square wells displayed flat cell and nuclear shapes similar to cells in monolayers. Local disruption of nuclear-cytoskeletal linkages resulted in spatial variation in vertical uniformity. These results suggest that competition between cell-cell pulling forces that expand and shorten the vertical cell cross-section, thereby widening and flattening the nucleus, and the resistance of the nucleus to further flattening results in uniform cell and nuclear cross-sections. Our results reveal the mechanical principles of self-organized vertical uniformity in cell monolayers. PMID:26795751

  5. nuclei

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    Minkov N.

    2016-01-01

    Full Text Available We study the effects of quadrupole-octupole deformations on the energy and magnetic properties of high-K isomeric states in even-even heavy and superheavy nuclei. The neutron two-quasiparticle (2qp isomeric energies and magnetic dipole moments are calculated within a deformed shell model with the Bardeen-Cooper- Schrieffer (BCS pairing interaction over a wide range of quadrupole and octupole deformations. We found that in most cases the magnetic moments exhibit a pronounced sensitivity to the octupole deformation, while the 2qp energies indicate regions of nuclei in which the presence of high-K isomeric states may be associated with the presence of octupole softness or even with octupole deformation. In the present work we also examine the influence of the BCS pairing strength on the energy of the blocked isomer configuration. We show that the formation of 2qp energy minima in the space of quadrupole-octupole and eventually higher multipolarity deformations is a subtle effect depending on nuclear pairing correlations.

  6. Computational hepatocellular carcinoma tumor grading based on cell nuclei classification.

    Science.gov (United States)

    Atupelage, Chamidu; Nagahashi, Hiroshi; Kimura, Fumikazu; Yamaguchi, Masahiro; Tokiya, Abe; Hashiguchi, Akinori; Sakamoto, Michiie

    2014-10-01

    Hepatocellular carcinoma (HCC) is the most common histological type of primary liver cancer. HCC is graded according to the malignancy of the tissues. It is important to diagnose low-grade HCC tumors because these tissues have good prognosis. Image interpretation-based computer-aided diagnosis (CAD) systems have been developed to automate the HCC grading process. Generally, the HCC grade is determined by the characteristics of liver cell nuclei. Therefore, it is preferable that CAD systems utilize only liver cell nuclei for HCC grading. This paper proposes an automated HCC diagnosing method. In particular, it defines a pipeline-path that excludes nonliver cell nuclei in two consequent pipeline-modules and utilizes the liver cell nuclear features for HCC grading. The significance of excluding the nonliver cell nuclei for HCC grading is experimentally evaluated. Four categories of liver cell nuclear features were utilized for classifying the HCC tumors. Results indicated that nuclear texture is the dominant feature for HCC grading and others contribute to increase the classification accuracy. The proposed method was employed to classify a set of regions of interest selected from HCC whole slide images into five classes and resulted in a 95.97% correct classification rate. PMID:26158066

  7. Mapping eGFP Oligomer Mobility in Living Cell Nuclei

    Science.gov (United States)

    Zwerger, Monika; Müller, Gabriele; Waldeck, Waldemar; Langowski, Jörg

    2009-01-01

    Movement of particles in cell nuclei can be affected by viscosity, directed flows, active transport, or the presence of obstacles such as the chromatin network. Here we investigate whether the mobility of small fluorescent proteins is affected by the chromatin density. Diffusion of inert fluorescent proteins was studied in living cell nuclei using fluorescence correlation spectroscopy (FCS) with a two-color confocal scanning detection system. We first present experiments exposing FCS-specific artifacts encountered in live cell studies as well as strategies to prevent them, in particular those arising from the choice of the fluorophore used for calibration of the focal volume, as well as temperature and acquisition conditions used for fluorescence fluctuation measurements. After defining the best acquisition conditions, we show for various human cell lines that the mobility of GFP varies significantly within the cell nucleus, but does not correlate with chromatin density. The intranuclear diffusional mobility strongly depends on protein size: in a series of GFP-oligomers, used as free inert fluorescent tracers, the diffusion coefficient decreased from the monomer to the tetramer much more than expected for molecules free in aqueous solution. Still, the entire intranuclear chromatin network is freely accessible for small proteins up to the size of eGFP-tetramers, regardless of the chromatin density or cell line. Even the densest chromatin regions do not exclude free eGFP-monomers or multimers. PMID:19347038

  8. Mapping eGFP oligomer mobility in living cell nuclei.

    Directory of Open Access Journals (Sweden)

    Nicolas Dross

    Full Text Available Movement of particles in cell nuclei can be affected by viscosity, directed flows, active transport, or the presence of obstacles such as the chromatin network. Here we investigate whether the mobility of small fluorescent proteins is affected by the chromatin density. Diffusion of inert fluorescent proteins was studied in living cell nuclei using fluorescence correlation spectroscopy (FCS with a two-color confocal scanning detection system. We first present experiments exposing FCS-specific artifacts encountered in live cell studies as well as strategies to prevent them, in particular those arising from the choice of the fluorophore used for calibration of the focal volume, as well as temperature and acquisition conditions used for fluorescence fluctuation measurements. After defining the best acquisition conditions, we show for various human cell lines that the mobility of GFP varies significantly within the cell nucleus, but does not correlate with chromatin density. The intranuclear diffusional mobility strongly depends on protein size: in a series of GFP-oligomers, used as free inert fluorescent tracers, the diffusion coefficient decreased from the monomer to the tetramer much more than expected for molecules free in aqueous solution. Still, the entire intranuclear chromatin network is freely accessible for small proteins up to the size of eGFP-tetramers, regardless of the chromatin density or cell line. Even the densest chromatin regions do not exclude free eGFP-monomers or multimers.

  9. Development of a stained cell nuclei counting system

    Science.gov (United States)

    Timilsina, Niranjan; Moffatt, Christopher; Okada, Kazunori

    2011-03-01

    This paper presents a novel cell counting system which exploits the Fast Radial Symmetry Transformation (FRST) algorithm [1]. The driving force behind our system is a research on neurogenesis in the intact nervous system of Manduca Sexta or the Tobacco Hornworm, which was being studied to assess the impact of age, food and environment on neurogenesis. The varying thickness of the intact nervous system in this species often yields images with inhomogeneous background and inconsistencies such as varying illumination, variable contrast, and irregular cell size. For automated counting, such inhomogeneity and inconsistencies must be addressed, which no existing work has done successfully. Thus, our goal is to devise a new cell counting algorithm for the images with non-uniform background. Our solution adapts FRST: a computer vision algorithm which is designed to detect points of interest on circular regions such as human eyes. This algorithm enhances the occurrences of the stained-cell nuclei in 2D digital images and negates the problems caused by their inhomogeneity. Besides FRST, our algorithm employs standard image processing methods, such as mathematical morphology and connected component analysis. We have evaluated the developed cell counting system with fourteen digital images of Tobacco Hornworm's nervous system collected for this study with ground-truth cell counts by biology experts. Experimental results show that our system has a minimum error of 1.41% and mean error of 16.68% which is at least forty-four percent better than the algorithm without FRST.

  10. Appearance of differentiated cells derived from polar body nuclei in the silkworm, Bombyx mori

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    Hiroki eSakai

    2013-09-01

    Full Text Available AbstractIn Bombyx mori, polar body nuclei are observed until 9h after egg lying, however, the fate of polar body nuclei remains unclear. To examine the fate of polar body nuclei, we employed a mutation of serosal cell pigmentation, pink-eyed white egg (pe. The heterozygous pe/+pe females produced black serosal cells in white eggs, while pe/pe females did not produce black serosal cells in white eggs. These results suggest that the appearance of black serosal cells in white eggs depends on the genotype (pe/ +pe of the mother. Because the polar body nuclei had +pe genes in the white eggs laid by a pe/ +pe female, polar body nuclei participate in development and differentiate into functional cell (serosal cells. Analyses of serosal cells pigmentation indicated that approximately 30% of the eggs contained polar-body-nucleus-derived cells. These results demonstrate that polar-body-nucleus-derived cells appeared at a high frequency under natural conditions. Approximately 80% of polar-body-nucleus-derived cells appeared near the anterior pole and the dorsal side, which is opposite to where embryogenesis occurs. The number of cells derived from the polar body nuclei was very low. Approximately 26 % of these eggs contained only one black serosal cell. PCR-based analysis revealed that the polar-body-nucleus-derived cells disappeared in late embryonic stages (stage 25. Overall, polar-body-nuclei-derived cells were unlikely to contribute to embryos.

  11. Bulk isolation in nonaqueous media of nuclei from lyophilized cells.

    Science.gov (United States)

    Kirsch, W M; Leitner, J W; Gainey, M; Schulz, D; Lasher, R; Nakane, P

    1970-06-26

    Intact lyophilized nuclei are obtainable from a variety of tissues, either in situ or in culture, by freezing at -156 degrees C, drying at -25 degrees C, and mechanical disassociation in glycerol at 2 degrees C. Centrifugal separation of nuclei is accomplished in an 85 : 15 by volume mixture of glycerol and 3-chloro-1,2 propanediol at 2 degrees C. The method gives homogeneous nuclear preparations in high yield with preservation of labile and water-soluble constituents. PMID:4316024

  12. ''Tailed'' nuclei are a possible cell marker of radiational effects

    International Nuclear Information System (INIS)

    Study of peripheral blood smears from irradiated patients (liquidators of consequences of the Chernobyl Atomic Electric Plant accident) has shown nuclei of some lymphocytes to have a protrusion into the cytoplasm. Such abnormal nuclei are called ''tailed'' nuclei (TN). The mean frequency of appearance of lymphocytes with TN in the group of irradiated patients (n=136) amounted to 0.59%, whereas in the group of healthy donors (n=50), 0.15% (the difference between the groups is statistically significant). The correlation coefficient between the indicators ''frequency of lymphocytes with NT'' and ''frequency of lymphocytes with dicentric chromosomes'' was 0.73 (n=47, p<0.001). By the method of bicolour FISH there was revealed localization of the near-centromere (not more than two signals) and telomere (not more than one signal) regions in the nuclear ''tails''. Abnormalities of the TN type in lymphocytes are likely to result from breakdowns of chromosomal bridges formed by dicentric chromosomes. (author)

  13. Identification of cardiomyocyte nuclei and assessment of ploidy for the analysis of cell turnover

    International Nuclear Information System (INIS)

    Assays to quantify myocardial renewal rely on the accurate identification of cardiomyocyte nuclei. We previously 14C birth dated human cardiomyocytes based on the nuclear localization of cTroponins T and I. A recent report by Kajstura et al. suggested that cTroponin I is only localized to the nucleus in a senescent subpopulation of cardiomyocytes, implying that 14C birth dating of cTroponin T and I positive cell populations underestimates cardiomyocyte renewal in humans. We show here that the isolation of cell nuclei from the heart by flow cytometry with antibodies against cardiac Troponins T and I, as well as pericentriolar material 1 (PCM-1), allows for isolation of close to all cardiomyocyte nuclei, based on ploidy and marker expression. We also present a reassessment of cardiomyocyte ploidy, which has important implications for the analysis of cell turnover, and iododeoxyuridine (IdU) incorporation data. These data provide the foundation for reliable analysis of cardiomyocyte turnover in humans.

  14. Studies on the Developmental Potentiality of Cultured Cell Nuclei of Fish

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    Hongxi Chen, Yonglan Yi, Minrong Chen, Xingqi Yang

    2010-01-01

    Full Text Available By means of the serial nuclear transplantation technique, the authors obtained a nuclear transplant fish from subcultured cell originated from the blastula cells of the crucian carp (Carassius auratus Linnaeus. This nuclear transplant fish survived for three years, but its sexual glands were undifferentiated. The authors have also obtained a sexually mature adult fish from short-term cultured kidney cell nucleus of an adult crucian carp. Results of the experiment implied that the subcultured cell nuclei of fish blastula cells and the specialized somatic cell nuclei of adult fish still retained their developmental totipotency, and thus, it indicated that there is a possibility of fish somatic cell breeding through the use of nuclear transplantation.

  15. DNA level in mucous membrane cell nuclei in rectal cancer during preoperative radiotherapy

    International Nuclear Information System (INIS)

    A microspectrophotometric study was made of DNA in cell nuclei of the normal mucous membrane and rectal tumors in 47 patients prior to and after irradiation at doses of 20, 40 and 36 Gy together with the administration of 7 g of 5-FU. Rectal adenocarcinoma is characterized by polyploidy, an increase in the ''DNA accumulation index'' that grows with a decrease in the dgree of tumor differentiation. A slightly raised ''DNA accumulation index'' is noted in the unchanged rectal mucosa after radio- and chemotherapy, signs of noticeable poly- and heteroploidy of the nuclei of the preserved cells were established in adenocarcinomas

  16. Fluorescent Magnesium Nanocomplex in Protein Scaffold for Cell Nuclei Imaging Application

    Energy Technology Data Exchange (ETDEWEB)

    Pandya, Alok [Ahmedabad Univ. (India); Tripathi, Apritam [Ahmedabad Univ. (India); Purohit, Rahul [Ahmedabad Univ. (India); Singh, Sanjay [Ahmedabad Univ. (India); Nandasiri, Manjula I. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Karakoti, Ajay S. [Ahmedabad Univ. (India); Singh, Surinder P. [National Physical Lab., New Delhi (India); Shanker, Rishi [Ahmedabad Univ. (India)

    2015-10-27

    Here in, we report a facile strategy for the synthesis of water-soluble ultra-fine blue emitting fluorescent Magnesium nanoparticles-protein complex (MgNC). This MgNC is demonstrated to exhibit excellent photo stability and biocompatibility. It was also observed that MgNC stain cell nuclei with high specifcity.

  17. Cytophotometric investigation of DNA and RNA content in nuclei of active Strasburger cells in Pinus nigra var. austriaca (Hoess) Badoux.

    Science.gov (United States)

    Sauter, J J; Ulrich, H

    1977-01-01

    The nuclei of active, sieve cell-associated Strasburger cells in the secondary phloem of Pinus nigra var. austriaca (Hoess) Badoux have been studied for their structure and DNA and RNA content. No difference in size compared to those of ordinary ray cells was found. The nuclear surface is often increased by an ameboid or lobed shape. The amount of highly decondensed chromatin is greatly increased. Cytophotometric measurements of DNA content of both Feulgen and gallocyanine chromalum-stained nuclei showed normal DNA levels and proved absence of endomitotic polyploidization. RNA content, however, was significantly increased as compared to nuclei of young Strasburger cells and of ordinary ray parenchyma cells. PMID:24420510

  18. Isolation of cell nuclei using inert macromolecules to mimic the crowded cytoplasm.

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    Hancock, Ronald; Hadj-Sahraoui, Yasmina

    2009-01-01

    Cell nuclei are commonly isolated and studied in media which include millimolar concentrations of cations, which conserve the nuclear volume by screening the negative charges on chromatin and maintaining its compaction. However, two factors question if these ionic conditions correctly reproduce the environment of nuclei in vivo: the small-scale motion and conformation of chromatin in vivo are not reproduced in isolated nuclei, and experiments and theory suggest that small ions in the cytoplasm are not free in the soluble phase but are predominantly bound to macromolecules. We studied the possible role in maintaining the structure and functions of nuclei in vivo of a further but frequently overlooked property of the cytoplasm, the crowding or osmotic effects caused by diffusible macromolecules whose concentration, measured in several studies, is in the range of 130 mg/ml. Nuclei which conserved their volume in the cell and their ultrastructure seen by electron microscopy were released from K562 cells in media containing the inert polymer 70 kDa Ficoll (50% w/v) or 70 kDa dextran (35% w/v) to replace the diffusible cytoplasmic molecules which were dispersed on cell lysis with digitonin, with 100 microM K-Hepes buffer as the only source of ions. Immunofluorescence labelling and experiments using cells expressing GFP-fusion proteins showed that internal compartments (nucleoli, PML and coiled bodies, foci of RNA polymerase II) were conserved in these nuclei, and nascent RNA transcripts could be elongated. Our observations are consistent with the hypothesis that crowding by diffusible cytoplasmic macromolecules is a crucial but overlooked factor which supports the nucleus in vivo by equilibrating the opposing osmotic pressure cause by the high concentration of macromolecules in the nucleus, and suggest that crowded media provide more physiological conditions to study nuclear structure and functions. They may also help to resolve the long-standing paradox that the small

  19. Embryonic stem cells generated by nuclear transfer of human somatic nuclei into rabbit oocytes

    Institute of Scientific and Technical Information of China (English)

    YING CHEN; QING ZHANG YANG; DA YUAN CHEN; MIN KANG WANG; JIN SONG LI; SHAO LIANG HUANG; XIANG YIN KONG; YAO ZHOU SHI; ZHI QIANG WANG; JIA HUI XIA; ZHI GAO LONG; ZHI XU HE; ZHI GANG XUE; WEN XIANG DING; HUI ZHEN SHENG; AILIAN LIU; KAI WANG; WEN WEI MAO; JIAN XIN CHU; YONG LU; ZHENG FU FANG; YING TANG SHI

    2003-01-01

    To solve the problem of immune incompatibility, nuclear transplantation has been envisaged as a means to produce cells or tissues for human autologous transplantation. Here we have derived embryonic stem cells by the transfer of human somatic nuclei into rabbit oocytes. The number of blastocysts that developed from the fused nuclear transfer was comparable among nuclear donors at ages of 5, 42, 52 and 60 years, and nuclear transfer (NT) embryonic stem cells (ntES cells) were subsequently derived from each of the four age groups. These results suggest that human somatic nuclei can form ntES cells independent of the age of the donor. The derived ntES cells are human based on karyotype, isogenicity, in situ hybridization, PGR and immunocytochemistry with probes that distinguish between the various species. The ntES cells maintain the capability of sustained growth in an undifferentiated state, and form embryoid bodies, which, on further induction, give rise to cell types such as neuron and muscle, as well as mixed cell populations that express markers representative of all three germ layers. Thus, ntES cells derived from human somatic cells by NT to rabbit eggs retain phenotypes similar to those of conventional human ES cells, including the ability to undergo multilineage cellular differentiation.

  20. Three-dimensional reconstruction of cell nuclei, internalized quantum dots and sites of lipid peroxidation

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    Maysinger Dusica

    2006-10-01

    Full Text Available Abstract Background The purpose of the study was to develop and illustrate three-dimensional (3-D reconstruction of nuclei and intracellular lipid peroxidation in cells exposed to oxidative stress induced by quantum dots. Programmed cell death is characterized by multiple biochemical and morphological changes in different organelles, including nuclei, mitochondria and lysosomes. It is the dynamics of the spatio-temporal changes in the signalling and morphological adaptations which will ultimately determine the 'shape' and fate of the cell. Results We present new approaches to the 3-D reconstruction of organelle morphology and biochemical changes in confocal live-cell images. We demonstrate the 3-D shapes of nuclei, the 3-D intracellular distributions of QDs and the accompanying lipid-membrane peroxidation, and provide methods for quantification. Conclusion This study provides an approach to 3-D organelle and nanoparticle visualization in the context of cell death; however, this approach is also applicable more generally to investigating changes in organelle morphology in response to therapeutic interventions, stressful stimuli and internalized nanoparticles. Moreover, the approach provides quantitative data for such changes, which will help us to better integrate compartmentalization of subcellular events and to link morphological and biochemical changes with physiological outcomes.

  1. Proteomic analysis of barley cell nuclei purified by flow sorting

    Czech Academy of Sciences Publication Activity Database

    Petrovská, Beáta; Jeřábková, Hana; Chamrád, I.; Vrána, Jan; Lenobel, R.; Uřinovská, J.; Šebela, M.; Doležel, Jaroslav

    2014-01-01

    Roč. 143, 1-3 (2014), s. 78-86. ISSN 1424-8581 R&D Projects: GA ČR GBP501/12/G090; GA ČR(CZ) GA14-28443S; GA MŠk(CZ) LO1204 Institutional support: RVO:61389030 Keywords : Cell cycle * Chromatin * Flow cytometry Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 1.561, year: 2014 http://gateway.isiknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=Alerting&SrcApp=Alerting&DestApp=MEDLINE&DestLinkType=FullRecord&UT=25059295

  2. Changes of DNA content of tumor cell nuclei in different types of irradiation

    International Nuclear Information System (INIS)

    Comparative evaluation of the state of tumour cells in patients with larynx cancer under various types of radiation action in isoeffective doses using the method of DNA cytophotometry was made. It is shown that changes in tumour cell ploidy occur in cases of: 1) operative treatment without irradiation; 2) preoperational photon therapy; 3) preoperational photon-neutron therapy; 4) preoperational neutron therapy. In all the cases preoperational course of treatment by radiotherapy amounted to 35-40 Gy. It is shown that DNA content in nuclei, index of DNA accumulation, ploidy permit an objective evaluation of dynamics of tumour cell state after irradiation. 8 refs.; 1 fig

  3. A study of the DNA content of cancer cell nuclei at the time of radiation therapy

    International Nuclear Information System (INIS)

    Radiation is very effective in the treatment of cervical cancer, but there are some patients who are less responsive to radiation, and responsivensss to radiation is still a clinically important problem to be solved in the future. In this study I have measured changes of the DNA content of cancer cell nuclei induced by radiation therapy in 26 patients with cervical cancer (squamous epithelial cancer) and have made histological investigation of the cancer at the same time in order to examine morphological judgment of the therapeutic effect of radiation not only from quantitative viewpoint of morphological changes but also from qualitative viewpoint of changes in cell nuclei. From the result of the present study it is seen that among the histological methods for judgment of the effect of radiation therapy, Oboshi and Shimozato's classification is a method hitherto in use, nearly agree with the result of the investigation of the DNA content hitherto in use and the classification of histological response nearly agrees with the judgment by DNA content of responsive grade, that is, evaluation by the former could be proved by the latter. However, we hold an opinion different from theirs as to the response grade GIII. When a patient is graded GIII, gualitative examination of the DNA content of nuclei is considered to be inevitable in order to confirm the non-viability of the cancer cells. (author)

  4. 60Co-γ-irradiation of dried DNA and isolated cell nuclei of chicken erythrocytes

    International Nuclear Information System (INIS)

    In this work low molecular products, which resulted from γ-irradiation of dried DNA, were isolated and quantitatively determined. Unchanged nucleic bases were released. The irradiation was successful in a vacuum as well as in oxygen. In the case of the drily irradiated DNA, the base release made up 30% of the total strand breaks. The release of DNA bases was also first studied in cell nuclei of eucaryotic cells, the erythrocyte nuclei of chicken blood. The second part of this work dealt with the isolation and identification of radiation induced changes in the 2-dioxyribose unit of DNA. In the third part it was investigated, whether as a result of γ-irradiation of DNA malonic dialdehyde was formed. It could be shown that neither malonic aldehyde nor basic propenal were formed, but instead products, which were still bound to the DNA and formed a chromophore with 2-thio barbituric acid. In this work the direct irradiation effect was investigated in DNA systems as well as in erythrocyte nuclei. By the isolation of low molecular irradiation products this work offers a contribution to the understanding of the irradiation chemistry in an eucaryotic cell, in which the direct effect on the DNA and the resulting radiation damage were given a deciding role for genetic information. (orig./MG)

  5. DNA level in guard cells nuclei of Ornithogalum umbellatum ovary is 2C-4C

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    Maria Kwiatkowska

    2011-04-01

    Full Text Available The DNA content after Feulgen reaction in the guard cells and epidermis of Omithogalum umbellatum ovary was cytophotometrically measured in different phases of flower development. Only in bud of flowers guard cells DNA content was 2C while in full blown flowers it was higher, between 2C-4C. This observation was supported by autoradiographic studies with 3H-thymidine which was incorporated into guard cell nuclei in the ovary epidermis of newly developed flowers. Thus DNA level in O. umbellatum guard cells was higher than those in other plants described in literature. On the other hand, DNA content in the epidermis cells increased gradually with ovary growth reaching the maximum level of 8C in some cells.

  6. Nuclei of non-muscle cells bind centrosome proteins upon fusion with differentiating myoblasts.

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    Xavier Fant

    Full Text Available BACKGROUND: In differentiating myoblasts, the microtubule network is reorganized from a centrosome-bound, radial array into parallel fibres, aligned along the long axis of the cell. Concomitantly, proteins of the centrosome relocalize from the pericentriolar material to the outer surface of the nucleus. The mechanisms that govern this relocalization are largely unknown. METHODOLOGY: In this study, we perform experiments in vitro and in cell culture indicating that microtubule nucleation at the centrosome is reduced during myoblast differentiation, while nucleation at the nuclear surface increases. We show in heterologous cell fusion experiments, between cultures of differentiating mouse myoblasts and human cells of non-muscular origin, that nuclei from non-muscle cells recruit centrosome proteins once fused with the differentiating myoblasts. This recruitment still occurs in the presence of cycloheximide and thus appears to be independent of new protein biosynthesis. CONCLUSIONS: Altogether, our data suggest that nuclei of undifferentiated cells have the dormant potential to bind centrosome proteins, and that this potential becomes activated during myoblast differentiation.

  7. ENHANCEMENT OF NIH3T3 CELL PROLIFERATION BY EXPRESSING MACROPHAGE COLONY STIMULATING FACTOR IN NUCLEI

    Institute of Scientific and Technical Information of China (English)

    曹震宇; 吴克复; 李戈; 林永敏; 张斌; 郑国光

    2003-01-01

    Objective: To explore the effects of nuclear M-CSF on the process of tumorigenesis. Methods: Functional part of M-CSF cDNA was inserted into an eukaryotic expression plasmid pCMV/myc/nuc, which can add three NLS to the C-terminal of the expressed protein and direct the protein into the cell nuclei. The constructed plasmid was transferred into NIH3T3 cells and the cell clones were selected by G-418 selection. Cell clones stable expressing target protein were identified by RT-PCR, ABC immunohistochemistry assay and Western blot. Cell growth kinetics analyses through growth curves, cell doubling time, MTT test and anti-sense oligodeoxynucleotide (ASODN) inhibiting cell growth test were performed to identify cells proliferation potential. Results: The transfected cells showed elevated proliferation potential over the control cells. Conclusion: Abnormal appearance of M-CSF in nucleus could enhance cell proliferation, which suggests that cytokine isoforms within cell nucleus might play transcription factor-like role.

  8. Germ cell mutagenesis in medaka fish after exposures to high-energy cosmic ray nuclei: A human model

    OpenAIRE

    Shimada, Atsuko; Akihiro SHIMA; Nojima, Kumie; Seino, Yo; Setlow, Richard B.

    2005-01-01

    Astronauts beyond the Earth's orbit are exposed to high-energy cosmic-ray nuclei with high values of linear energy transfer (LET), resulting in much more biological damage than from x-rays or γ-rays and may result in mutations and cancer induction. The relative biological effectiveness of these nuclei depends on the LET, rising to as high as ≈50 at LET values of ≈100-200 keV/μm. An endpoint of concern is germ cell mutations passed on to offspring, arising from exposure to these nuclei. A vert...

  9. Human mitochondrial transcription factor A functions in both nuclei and mitochondria and regulates cancer cell growth

    International Nuclear Information System (INIS)

    Highlights: → Mitochondrial transcription factor A (mtTFA) localizes in nuclei and binds tightly to the nuclear chromatin. → mtTFA contains two putative nuclear localization signals (NLS) in the HMG-boxes. → Overexpression of mtTFA enhances the growth of cancer cells, whereas downregulation of mtTFA inhibits their growth by regulating mtTFA target genes, such as baculoviral IAP repeat-containing 5 (BIRC5; also known as survivin). → Knockdown of mtTFA expression induces p21-dependent G1 cell cycle arrest. -- Abstract: Mitochondrial transcription factor A (mtTFA) is one of the high mobility group protein family and is required for both transcription from and maintenance of mitochondrial genomes. However, the roles of mtTFA have not been extensively studied in cancer cells. Here, we firstly reported the nuclear localization of mtTFA. The proportion of nuclear-localized mtTFA varied among different cancer cells. Some mtTFA binds tightly to the nuclear chromatin. DNA microarray and chromatin immunoprecipitation assays showed that mtTFA can regulate the expression of nuclear genes. Overexpression of mtTFA enhanced the growth of cancer cell lines, whereas downregulation of mtTFA inhibited their growth by regulating mtTFA target genes, such as baculoviral IAP repeat-containing 5 (BIRC5; also known as survivin). Knockdown of mtTFA expression induced p21-dependent G1 cell cycle arrest. These results imply that mtTFA functions in both nuclei and mitochondria to promote cell growth.

  10. High resolution image analysis of cell nuclei in tissue sections of primary and metastatic carcinomas.

    Science.gov (United States)

    Theissig, F; Dimmer, V; Kunze, K D

    1986-01-01

    The present study examines whether certain histological tumour types can be differentiated on account of their nuclear image with the aid of automated image analysis. For karyometric investigations three tumour types (adenocarcinomas, squamous cell carcinomas and mammary carcinomas) were chosen, which occur frequently as occult primary tumours. From each type ten primary tumours with their corresponding lymph node metastases were examined. 100 cell nuclei were measured from each case using 4 micron thick paraffin sections stained with gallocyanin-chromalum. For each cell nucleus 21 contour and texture features were determined. Through the application of linear classifiers 41 out of 52 cases (25 primary tumours, 27 metastases) of these three tumour types were correctly classified. Eight cases could not be classified with certainty and only three cases were wrongly classified. In addition, within the group of adenocarcinomas differences due to localisation were detected which allow us to draw conclusions on the seat of the primary tumour. PMID:3019272

  11. Nuclear Transfer of Embryonic Cell Nuclei to Non-enucleated Eggs in Zebrafish, Danio rerio

    Directory of Open Access Journals (Sweden)

    Manabu Hattori, Hisashi Hashimoto, Ekaterina Bubenshchikova, Yuko Wakamatsu

    2011-01-01

    Full Text Available We previously established a novel method for nuclear transfer in medaka (Oryzias latipes using non-enucleated, diploidized eggs as recipients for adult somatic cell nuclei. Here we report the first attempt to apply this method to another fish species. To examine suitability of using non-enucleated eggs as recipients for nuclear transfer in the zebrafish (Danio rerio, we transferred blastula cell nuclei from a wild-type donor strain to non-enucleated, unfertilized eggs from a golden recipient strain. As a result, 31 of 184 (16.8% operated eggs developed normally and reached the adult stage. Twenty-eight (15.2% of these transplants showed wild-type phenotype and the remaining three (1.6% were golden. Except for one individual that exhibited diploid/tetraploid mosaicism, all of the wild-type nuclear transplants were either triploid or diploid. While all of 19 triploid transplants were infertile, a total of six transplants (21.4% were fertile (five of the eight diploid transplants and one transplant exhibiting ploidy mosaicism. Except for one diploid individual, all of the fertile transplants transferred both the wild-type golden gene allele (slc24a5 as well as the phenotype, the wild-type body color, to their F1 and F2 progeny in a typical Mendelian fashion. PCR analysis of slc24a5 suggested that triploidy originated from a fused nucleus in the diploid donor and haploid recipient nuclei, and that the sole origin of diploidy was the diploid donor nucleus. The results of the present study demonstrated the suitability of using non-enucleated eggs as recipients for nuclear transfer experiments in zebrafish.

  12. Hit rates and radiation doses to nuclei of bone lining cells from alpha-particle-emitting radionuclides

    Science.gov (United States)

    Polig, E.; Jee, W. S.; Kruglikov, I. L.

    1992-01-01

    Factors relating the local concentration of a bone-seeking alpha-particle emitter to the mean hit rate have been determined for nuclei of bone lining cells using a Monte Carlo procedure. Cell nuclei were approximated by oblate spheroids with dimensions and location taken from a previous histomorphometric study. The Monte Carlo simulation is applicable for planar and diffuse labels at plane or cylindrical bone surfaces. Additionally, the mean nuclear dose per hit, the dose mean per hit, the mean track segment length and its second moment, the percentage of stoppers, and the frequency distribution of the dose have been determined. Some basic features of the hit statistics for bone lining cells have been outlined, and the consequences of existing standards of radiation protection with regard to the hit frequency to cell nuclei are discussed.

  13. Single Molecule Localization Microscopy of Mammalian Cell Nuclei on the Nanoscale.

    Science.gov (United States)

    Szczurek, Aleksander; Xing, Jun; Birk, Udo J; Cremer, Christoph

    2016-01-01

    Nuclear texture analysis is a well-established method of cellular pathology. It is hampered, however, by the limits of conventional light microscopy (ca. 200 nm). These limits have been overcome by a variety of super-resolution approaches. An especially promising approach to chromatin texture analysis is single molecule localization microscopy (SMLM) as it provides the highest resolution using fluorescent based methods. At the present state of the art, using fixed whole cell samples and standard DNA dyes, a structural resolution of chromatin in the 50-100 nm range is obtained using SMLM. We highlight how the combination of localization microscopy with standard fluorophores opens the avenue to a plethora of studies including the spatial distribution of DNA and associated proteins in eukaryotic cell nuclei with the potential to elucidate the functional organization of chromatin. These views are based on our experience as well as on recently published research in this field. PMID:27446198

  14. Structural components of the nuclear body in nuclei of Allium cepa cells

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Nuclear bodies have long been noted in interphase nuclei of plant cells,but their structural component,origin and function are still unclear by now.The present work showed in onion cells the nuclear bodies appeared as a spherical structure about 0.3 to 0.8 μm in diameter.They possibly were formed in nucleolus and subsequently released,and entered into nucleoplasm.Observation through cytochemical staining method at the ultrastructural level confirmed that nuclear bodies consisted of ribonucleoproteins (RNPs) and silver-stainable proteins.Immunocytochemical results revealed that nuclear bodies contained no DNA and ribosomal gene transcription factor (UBF).Based on these data,we suggested that nuclear bodies are not related to the ribosome or other gene transcription activities,instead they may act as subnuclear structures for RNPs transport from nucleolus to cytoplasm,and may also be involved in splicing of pre-mRNAs.

  15. Isolation of cell nuclei in microchannels by short-term chemical treatment via two-step carrier medium exchange.

    Science.gov (United States)

    Toyama, Kaori; Yamada, Masumi; Seki, Minoru

    2012-08-01

    Separation/purification of nuclei from cells is a critical process required for medical and biochemical research applications. Here, we report a flow-through microfluidic device for isolating cell nuclei by selectively digesting the cell membrane by using the concept of hydrodynamic filtration (HDF). When a cell suspension is continuously introduced into a microchannel (main channel) possessing multiple side channels, cells flow through the main channel, whereas the carrier medium of the cells is drained through the side channels. Introductions of a cell treatment solution containing a surfactant and a washing buffer enable the two-step exchange of the carrier-medium and the cell treatment by the surfactant for a short span of time. The precise control of the treatment time by changing the flow rate and/or the size of the microchannel enables the selective digestion of cell membranes, resulting in the isolation of cell nuclei after separation from membrane debris and cytoplasmic components according to size. We examined several surfactant molecules and demonstrated that Triton X-100 exhibited high efficiency regarding nucleus isolation for both adherent (HeLa) and nonadherent (JM) cells, with a recovery ratio of ~80 %. In addition, the isolation efficiency was evaluated by western blotting. The presented flow-through microfluidic cell-nucleus separator may be a useful tool for general biological applications, because of its simplicity in operation, high reproducibility, and accuracy. PMID:22544390

  16. Basic dyes in the staining of DNA-phosphate groups and DNA-aldehyde molecules in cell nuclei

    International Nuclear Information System (INIS)

    A novel method is presented for the staining of cell nuclei with aqueous solutions of Janus blue, methylene blue, and Janus red in tissue sections from which RNA has been extracted selectively with cold phosphoric acid. Not only this, DNA-aldehyde molecules can also be stained when tissue sections from which RNA has been extracted are then hydrolysed in 6 N hydrochloric acid at 300C for 15 min followed by staining with Janus blue, methylene blue, and Janus red. Following staining with any of these dyes, sections can be dried between folds of filter paper and then treated with n-butanol or passed through grades of ethanol, cleared in xylene and mounted. Staining with Janus blue has been considered to be metachromatic, particularly in the sections of the rectum in which glycogen stains blue-black and the nuclei purplish. An aqueous solution of methylene blue does also stain glycogen blue with similar colour of the nuclei while with Janus red both the nuclei as well as glycogen stain red. The in situ absorption spectra of the nuclei stained with the dyes mentioned, after selective extraction of RNA, reveal peaks of maximum absorption at 560-570 nm (Janus blue), at 600 and 640 nm (methylene blue), and at 530 nm (Janus red). Those of nuclei stained for DNA-aldehyde molecules are at 560 nm (Janus blue), at 600 and 630 nm (methylene blue), and at 520 nm (Janus red). Possible significance of these findings has been discussed. (orig.)

  17. Induction of Apoptosis in Purified Nuclei from Tobacco-Suspension Cells by Cytochrome b6/f Complex

    Institute of Scientific and Technical Information of China (English)

    张贵友; 李萍; 朱瑞宇; 田瑞华; 戴尧仁

    2004-01-01

    An apoptotic cell-free system containing cytosol and nuclei from normally cultured tobacco suspension cells was used to show that a spinach chloroplast preparation can induce apoptosis in nuclei,evidenced by DNA electrophoresis and fluorescence microscopy observations.Further study showed that the chloroplast preparation or its pellet (thylakoid membrane) after hypoosmotic or supersonic treatment still exhibited the apoptosis-inducing activity,but the supernatant had no effect,which indicates that the apoptosis-inducing effector in the chloroplast preparation is water-insoluble.The induction of apoptosis by chloroplast preparation could be attenuated by Ac-DEVD-CHO,the specific inhibitor of Caspase-3,implying involvement of a Caspase-3-like protease during the process.Furthermore,extensive apoptosis in nuclei was induced by cytochrome b6/f on the thylakoid membrane,indicating that this important cytochrome complex may have an important role in the chloroplast-related apoptotic pathway.

  18. Automated recognition of cell phenotypes in histology images based on membrane- and nuclei-targeting biomarkers

    International Nuclear Information System (INIS)

    Three-dimensional in vitro culture of cancer cells are used to predict the effects of prospective anti-cancer drugs in vivo. In this study, we present an automated image analysis protocol for detailed morphological protein marker profiling of tumoroid cross section images. Histologic cross sections of breast tumoroids developed in co-culture suspensions of breast cancer cell lines, stained for E-cadherin and progesterone receptor, were digitized and pixels in these images were classified into five categories using k-means clustering. Automated segmentation was used to identify image regions composed of cells expressing a given biomarker. Synthesized images were created to check the accuracy of the image processing system. Accuracy of automated segmentation was over 95% in identifying regions of interest in synthesized images. Image analysis of adjacent histology slides stained, respectively, for Ecad and PR, accurately predicted regions of different cell phenotypes. Image analysis of tumoroid cross sections from different tumoroids obtained under the same co-culture conditions indicated the variation of cellular composition from one tumoroid to another. Variations in the compositions of cross sections obtained from the same tumoroid were established by parallel analysis of Ecad and PR-stained cross section images. Proposed image analysis methods offer standardized high throughput profiling of molecular anatomy of tumoroids based on both membrane and nuclei markers that is suitable to rapid large scale investigations of anti-cancer compounds for drug development

  19. Osteoclast nuclei of myeloma patients show chromosome translocations specific for the myeloma cell clone: a new type of cancer-host partnership?

    DEFF Research Database (Denmark)

    Levin Andersen, Thomas; Boissy, Patrice; Sondergaard, T E;

    2007-01-01

    study demonstrates that bone-resorbing osteoclasts from myeloma patients contain nuclei with translocated chromosomes of myeloma B-cell clone origin, in addition to nuclei without these translocations, by using combined FISH and immunohistochemistry on bone sections. These nuclei of malignant origin are...... proximity of myeloma cells. Similar hybrid cells were generated in myeloma cell-osteoclast co-cultures, as revealed by tracing myeloma nuclei using translocations, bromo-deoxyuridine, or the Y chromosome of male myeloma cells in female osteoclasts. These observations indicate that hybrid cells can originate......A major clinical manifestation of bone cancers is bone destruction. It is widely accepted that this destruction is not caused by the malignant cells themselves, but by osteoclasts, multinucleated cells of monocytic origin that are considered to be the only cells able to degrade bone. The present...

  20. Phage T4 endonuclease V stimulates DNA repair replication in isolated nuclei from ultraviolet-irradiated human cells, including xeroderma pigmentosum fibroblasts

    International Nuclear Information System (INIS)

    The repair mode of DNA replication has been demonstrated in isolated nuclei from uv-irradiated human cells. Nuclei are incubated in a mixture containing [3H]thymidine triphosphate and bromodeoxyuridine triphosphate in a 1:5 ratio. The 3H at the density of parental DNA in alkaline CsCl density gradients is then a measure of repair. In nuclei prepared from WI38 cells 30 min after irradiation, repair replication is uv-dependent and proceeds at approximately the in vivo rate for 5 min. Repair replication is reduced in irradiated nuclei or in nuclei prepared immediately after irradiation. It is Mg2+-dependent and stimulated by added ATP and deoxyribonucleoside triphosphates. No repair replication is observed in nuclei from xeroderma pigmentosum (complementation group A) cells. However, upon addition of coliphage T4 endonuclease V, which specifically nicks DNA containing pyrimidine dimers, repair replication is observed in nuclei from irradiated xeroderma pigmentosum cells and is stimulated in WI38 nuclei. The reaction then persists for an hour and is dependent upon added ATP and deoxyribonucleoside triphosphates. The repair label is in stretches of roughly 35 nucleotides, as it is in intact cells. Added pancreatic DNase does not promote uv-dependent repair synthesis. Our results support the view that xeroderma pigmentosum (group A) cells are defective in the incision step of the DNA excision repair pathway, and demonstrate the utility of this system for probing DNA repair mechanisms

  1. Condensation of interphase chromatin in nuclei of synchronized chinese hamster ovary (CHO-K1) cells.

    Science.gov (United States)

    Gacsi, Mariann; Nagy, Gabor; Pinter, Gabor; Basnakian, Alexei G; Banfalvi, Gaspar

    2005-01-01

    Reversibly permeabilized cells have been used to visualize interphase chromatin structures in the presence and absence of biotinylated nucleotides. By reversing permeabilization, it was possible to confirm the existence of a flexible chromatin folding pattern through a series of transient geometric forms such as supercoiled, circular forms, chromatin bodies, thin and thick fibers, and elongated chromosomes. Our results show that the incorporation of biotin-11-dUTP interferes with chromatin condensation, leading to the accumulation of decondensed chromatin structures. Chromatin condensation without nucleotide incorporation was also studied in cell populations synchronized by centrifugal elutriation. After reversal of permeabilization, nuclei were isolated and chromatin structures were visualized after DAPI staining by fluorescent microscopy. Decondensed veil-like structures were observed in the early S phase (at an average C-value of 2.21), supercoiled chromatin later in the early S (2, 55 C), fibrous structures in the early mid S phase (2, 76 C), ribboned structures in the mid-S phase (2, 98 C), continuous chromatin strings later in the mid-S phase (3,28), elongated prechromosomes in the late S-phase (3, 72 C), precondensed chromosomes at the end and after the S phase (3, 99 C). Fluorescent microscopy revealed that neither interphase nor metaphase chromosomes are separate entities but form a linear array arranged in a semicircle. Linear arrangement was confirmed by computer image analysis. PMID:15684719

  2. DNA (deoxyribonucleic acid) synthesis following microinjection of heterologous sperm and somatic cell nuclei into hamster oocytes

    International Nuclear Information System (INIS)

    The authors investigated the ability of the hamster oocyte to initiate DNA synthesis in nuclei differing in basic protein content. DNA synthesis was studied by autoradiography in oocytes that had been incubated in 3H-thymidine after being parthenogenetically activated by sham microinjection, or microinjected with hamster, mouse, rabbit, or fish sperm nuclei, or hamster hepatocyte nuclei. Within 6 hr of sham or nucleus microinjection, nuclei of each type underwent transformation into pronuclei and synthesized DNA. These results demonstrated that the hamster egg can access and utilize its own and each type of template provided, whether homologous or heterologous. However, pronuclei derived from hamster sperm nuclei were more likely to be synthesizing DNA at 6 hr than pronuclei derived from sperm nuclei of other species. The authors conclude that the mechanisms employed by the hamster oocyte to transform hamster sperm nuclei into pronuclei and to effect DNA synthesis in these nuclei are not specific for the hamster sperm nucleus. Nevertheless, these mechanisms apparently operate more efficiently when the hamster sperm nucleus, rather than a heterologous sperm nucleus, is present

  3. Three-Dimensional, Live-Cell Imaging of Chromatin Dynamics in Plant Nuclei Using Chromatin Tagging Systems.

    Science.gov (United States)

    Hirakawa, Takeshi; Matsunaga, Sachihiro

    2016-01-01

    In plants, chromatin dynamics spatiotemporally change in response to various environmental stimuli. However, little is known about chromatin dynamics in the nuclei of plants. Here, we introduce a three-dimensional, live-cell imaging method that can monitor chromatin dynamics in nuclei via a chromatin tagging system that can visualize specific genomic loci in living plant cells. The chromatin tagging system is based on a bacterial operator/repressor system in which the repressor is fused to fluorescent proteins. A recent refinement of promoters for the system solved the problem of gene silencing and abnormal pairing frequencies between operators. Using this system, we can detect the spatiotemporal dynamics of two homologous loci as two fluorescent signals within a nucleus and monitor the distance between homologous loci. These live-cell imaging methods will provide new insights into genome organization, development processes, and subnuclear responses to environmental stimuli in plants. PMID:27557696

  4. Nuquantus: Machine learning software for the characterization and quantification of cell nuclei in complex immunofluorescent tissue images

    Science.gov (United States)

    Gross, Polina; Honnorat, Nicolas; Varol, Erdem; Wallner, Markus; Trappanese, Danielle M.; Sharp, Thomas E.; Starosta, Timothy; Duran, Jason M.; Koller, Sarah; Davatzikos, Christos; Houser, Steven R.

    2016-03-01

    Determination of fundamental mechanisms of disease often hinges on histopathology visualization and quantitative image analysis. Currently, the analysis of multi-channel fluorescence tissue images is primarily achieved by manual measurements of tissue cellular content and sub-cellular compartments. Since the current manual methodology for image analysis is a tedious and subjective approach, there is clearly a need for an automated analytical technique to process large-scale image datasets. Here, we introduce Nuquantus (Nuclei quantification utility software) - a novel machine learning-based analytical method, which identifies, quantifies and classifies nuclei based on cells of interest in composite fluorescent tissue images, in which cell borders are not visible. Nuquantus is an adaptive framework that learns the morphological attributes of intact tissue in the presence of anatomical variability and pathological processes. Nuquantus allowed us to robustly perform quantitative image analysis on remodeling cardiac tissue after myocardial infarction. Nuquantus reliably classifies cardiomyocyte versus non-cardiomyocyte nuclei and detects cell proliferation, as well as cell death in different cell classes. Broadly, Nuquantus provides innovative computerized methodology to analyze complex tissue images that significantly facilitates image analysis and minimizes human bias.

  5. Isolation of Plant Nuclei at Defined Cell Cycle Stages Using EdU Labeling and Flow Cytometry.

    Science.gov (United States)

    Wear, Emily E; Concia, Lorenzo; Brooks, Ashley M; Markham, Emily A; Lee, Tae-Jin; Allen, George C; Thompson, William F; Hanley-Bowdoin, Linda

    2016-01-01

    5-Ethynyl-2'-deoxyuridine (EdU) is a nucleoside analog of thymidine that can be rapidly incorporated into replicating DNA in vivo and, subsequently, detected by using "click" chemistry to couple its terminal alkyne group to fluorescent azides such as Alexa Fluor 488. Recently, EdU incorporation followed by coupling with a fluorophore has been used to visualize newly synthesized DNA in a wide range of plant species. One particularly useful application is in flow cytometry, where two-parameter sorting can be employed to analyze different phases of the cell cycle, as defined both by total DNA content and the amount of EdU pulse-labeled DNA. This approach allows analysis of the cell cycle without the need for synchronous cell populations, which can be difficult to obtain in many plant systems. The approach presented here, which was developed for fixed, EdU-labeled nuclei, can be used to prepare analytical profiles as well as to make highly purified preparations of G1, S, or G2/M phase nuclei for molecular or biochemical analysis. We present protocols for EdU pulse labeling, tissue fixation and harvesting, nuclei preparation, and flow sorting. Although developed for Arabidopsis suspension cells and maize root tips, these protocols should be modifiable to many other plant systems. PMID:26659955

  6. [Determination of the relative RNA-content of liver cell nuclei with gallocyanin-chromealum-staining (author's transl)].

    Science.gov (United States)

    Wenzelides, K; Korek, G; Voss, K

    1981-01-01

    The relative RNA-content of liver cell nuclei from histological slides of rat liver was determined by automatical microscope picture analysis. The slides were stained with Gallocyanin-Chromealum. Extinction measurements are made before and after perchloracid extraction of RNA for the same slide. The changes of extinction measurements caused by the changes of slide thickness and of tissue inhomogeneity could be lowered using this method. PMID:6177185

  7. Sexual Differences in Cell Loss during the Post-Hatch Development of Song Control Nuclei in the Bengalese Finch

    OpenAIRE

    Chen, XiaoNing; Li, Jia; Zeng, Lei; Zhang, Xuebo; Lu, Xiaohua; Mingxue ZUO; ZHANG, XINWEN; Zeng, Shaoju

    2015-01-01

    Birdsongs and the regions of their brain that control song exhibit obvious sexual differences. However, the mechanisms underlying these sexual dimorphisms remain unknown. To address this issue, we first examined apoptotic cells labeled with caspase-3 or TUNEL in Bengalese finch song control nuclei - the robust nucleus of the archopallium (RA), the lateral magnocellular nucleus of the anterior nidopallium (LMAN), the high vocal center (HVC) and Area X from post-hatch day (P) 15 to 120. Next, w...

  8. Laboratory studies with cloud-derived Bacterial Cells acting as Ice Nuclei in the Immersion and Deposition Mode

    Science.gov (United States)

    Oehm, C.; Chou, C.; Amato, P.; Attard, E.; Delort, A.-M.; Morris, C.; Kiselev, A.; Stetzer, O.; Möhler, O.; Leisner, T.

    2012-04-01

    Atmospheric aerosol particles play an important role in cloud microphysics. Aerosols of biological origin are a subgroup, and some of them are able to act as heterogeneous ice nuclei and thus influence cloud life cycles and the climate. Some bacteria species have been found to act as ice nuclei at relatively high temperatures up to -2 degree Celsius and are therefore of particular importance as "high temperature" ice nuclei. Recently, ice nucleation experiments with bacterial cells from different sources were performed at the aerosol and cloud simulation chamber AIDA at the Karlsruhe Institute of Technology. At the AIDA facility, microphysical cloud processes can be simulated and investigated in laboratory at realistic atmospheric cloud conditions. Different ice nucleation active (INA) bacteria strains were isolated from cloud water, glacier melt water and phyllosphere and examined in AIDA experiments. The living cells were suspended in nanopure or artificial cloud water and injected into the cloud chamber through a dispersion nozzle. The injected droplets evaporated in the chamber and the bacterial cells were transformed into the aerosol phase. After the spraying, the cloud formation was started by expansion cooling. Experiments were performed in the temperature range from -2 down to -20 degree Celsius. Detailed measurements of the number concentration and size distribution of the aerosol particles as well as of the droplets and ice particles were carried out during the AIDA experiments. A minor fraction of the bacteria cells was observed to act as ice nuclei in the immersion nucleation mode at higher temperatures as well as in the deposition nucleation mode at lower temperatures. The ice activity started at -6 degree Celsius. The most efficient INA bacteria species were Pseudomonas syringae 32b74 and Pseudomonas fluorescens Antarctica1. The ice active number fraction with respect to the cells varied from 0,01 to 0,1, and it does not change at different

  9. Sexual Differences in Cell Loss during the Post-Hatch Development of Song Control Nuclei in the Bengalese Finch.

    Directory of Open Access Journals (Sweden)

    XiaoNing Chen

    Full Text Available Birdsongs and the regions of their brain that control song exhibit obvious sexual differences. However, the mechanisms underlying these sexual dimorphisms remain unknown. To address this issue, we first examined apoptotic cells labeled with caspase-3 or TUNEL in Bengalese finch song control nuclei - the robust nucleus of the archopallium (RA, the lateral magnocellular nucleus of the anterior nidopallium (LMAN, the high vocal center (HVC and Area X from post-hatch day (P 15 to 120. Next, we investigated the expression dynamics of pro-apoptotic (Bid, Bad and Bax and anti-apoptotic (Bcl-2 and Bcl-xL genes in the aforementioned nuclei. Our results revealed that the female RA at P45 exhibited marked cell apoptosis, confirmed by low densities of Bcl-xL and Bcl-2. Both the male and female LMAN exhibited apoptotic peaks at P35 and P45, respectively, and the observed cell loss was more extensive in males. A corresponding sharp decrease in the density of Bcl-2 after P35 was observed in both sexes, and a greater density of Bid was noted at P45 in males. In addition, we observed that RA volume and the total number of BDNF-expressing cells decreased significantly after unilateral lesion of the LMAN or HVC (two areas that innervate the RA and that greater numbers of RA-projecting cells were immunoreactive for BDNF in the LMAN than in the HVC. We reasoned that a decrease in the amount of BDNF transported via HVC afferent fibers might result in an increase in cell apoptosis in the female RA. Our data indicate that cell apoptosis resulting from different pro- and anti-apoptotic agents is involved in generating the differences between male and female song control nuclei.

  10. Pseudomagic nuclei

    International Nuclear Information System (INIS)

    It has been shown previously that, below a critical angular momentum, yrast bands of non-magic nuclei are well described by the two-parameter variable moment of inertia model. Some striking exceptions to this rule are found in nuclei which have the same mass number as doubly magic nuclei but possess either one (or two) proton pairs beyond a magic number and one (or two) neutron hole pairs, or vice versa. Yrast bands in these 'pseudomagic' nuclei resemble those in magic nuclei. (author)

  11. Melanin-concentrating hormone (MCH) immunoreactivity in non-neuronal cells within the raphe nuclei and subventricular region of the brainstem of the cat.

    Science.gov (United States)

    Torterolo, Pablo; Lagos, Patricia; Sampogna, Sharon; Chase, Michael H

    2008-05-19

    Neurons that utilize melanin-concentrating hormone (MCH) as a neuromodulator are localized within the postero-lateral hypothalamus and zona incerta. These neurons project diffusely throughout the central nervous system and have been implicated in critical physiological processes such as energy homeostasis and sleep. In the present report, we examined the distribution of MCH immunoreactivity in the brainstem of the cat. In addition to MCH+ axons, we found MCH-immunoreactive cells that have not been previously described either in the midbrain raphe nuclei or in the periaqueductal and periventricular areas. These MCH+ cells constituted: 1. ependymal cells that lined the fourth ventricle and aqueduct, 2. ependymal cells with long basal processes that projected deeply into the subventricular (subaqueductal) parenchyma, and, 3. cells in subventricular regions and the midbrain raphe nuclei. The MCH+ cells in the midbrain raphe nuclei were closely related to neuronal processes of serotonergic neurons. Utilizing Neu-N and GFAP immunohistochemistry we determined that the preceding MCH+ cells were neither neurons nor astrocytes. However, we found that vimentin, an intermediate-filament protein that is used as a marker for tanycytes, was specifically co-localized with MCH in these cells. We conclude that MCH is present in tanycytes whose processes innervate the midbrain raphe nuclei and adjacent subependymal regions. Because tanycytes are specialized cells that transport substances from the cerebrospinal fluid (CSF) to neural parenchyma, we suggest that MCH is absorbed from the CSF by tanycytes and subsequently liberate to act upon neurons of brainstem nuclei. PMID:18410908

  12. DNA (DEOXYRIBONUCLEIC ACID) SYNTHESIS FOLLOWING MICROINJECTION OF HETEROLOGOUS SPERM AND SOMATIC CELL NUCLEI INTO HAMSTER OOCYTES

    Science.gov (United States)

    The authors have investigated the ability of the hamster oocyte to initiate DNA synthesis in nuclei differing in basic protein content. DNA synthesis was studied by autoradiography in oocytes that had been incubated in 3H-thymidine after being parthenogenetically activated by sha...

  13. Improved and robust detection of cell nuclei from four dimensional fluorescence images.

    Directory of Open Access Journals (Sweden)

    Md Khayrul Bashar

    Full Text Available Segmentation-free direct methods are quite efficient for automated nuclei extraction from high dimensional images. A few such methods do exist but most of them do not ensure algorithmic robustness to parameter and noise variations. In this research, we propose a method based on multiscale adaptive filtering for efficient and robust detection of nuclei centroids from four dimensional (4D fluorescence images. A temporal feedback mechanism is employed between the enhancement and the initial detection steps of a typical direct method. We estimate the minimum and maximum nuclei diameters from the previous frame and feed back them as filter lengths for multiscale enhancement of the current frame. A radial intensity-gradient function is optimized at positions of initial centroids to estimate all nuclei diameters. This procedure continues for processing subsequent images in the sequence. Above mechanism thus ensures proper enhancement by automated estimation of major parameters. This brings robustness and safeguards the system against additive noises and effects from wrong parameters. Later, the method and its single-scale variant are simplified for further reduction of parameters. The proposed method is then extended for nuclei volume segmentation. The same optimization technique is applied to final centroid positions of the enhanced image and the estimated diameters are projected onto the binary candidate regions to segment nuclei volumes.Our method is finally integrated with a simple sequential tracking approach to establish nuclear trajectories in the 4D space. Experimental evaluations with five image-sequences (each having 271 3D sequential images corresponding to five different mouse embryos show promising performances of our methods in terms of nuclear detection, segmentation, and tracking. A detail analysis with a sub-sequence of 101 3D images from an embryo reveals that the proposed method can improve the nuclei detection accuracy by 9% over

  14. Phospho-ERK1/2 levels in cancer cell nuclei predict responsiveness to radiochemotherapy of rectal adenocarcinoma

    DEFF Research Database (Denmark)

    Holck, Susanne; Nielsen, Hans Jørgen; Pedersen, Niels; Larsson, Lars-Inge

    2015-01-01

    immunohistochemistry for phosphorylated ERK (pERK). Immunostaining for pERK was considerably enhanced by use of alkaline demasking. Nuclear staining occurred in both cancer cells and stromal cells. Blind-coded sections were scored by 2 independent investigators. In patients showing no residual tumor after RCT (TRG1.......0007) and also predicted downstaging (area under curve: 0.76; p = 0.01). A number of controls documented the specificity of the optimized staining method and results were confirmed with another pERK antibody. Thus, staining for pERK in cancer cell nuclei can predict the response to RCT and may help spare......), staining for pERK in cancer, but not stromal, cell nuclei was significantly weaker than in patients showing a poor RCT response (TRG1 vs TRG4: p = 0.0001). Nuclear staining for pERK predicted poor responders, as illustrated by receiver operating characteristic curves with an area under curve of 0.86 (p = 0...

  15. Reduction of exportin 6 activity leads to actin accumulation via failure of RanGTP restoration and NTF2 sequestration in the nuclei of senescent cells

    International Nuclear Information System (INIS)

    We have previously reported that G-actin accumulation in nuclei is a universal phenomenon of cellular senescence. By employing primary culture of human diploid fibroblast (HDF) and stress-induced premature senescence (SIPS), we explored whether the failure of actin export to cytoplasm is responsible for actin accumulation in nuclei of senescent cells. Expression of exportin 6 (Exp6) and small G-protein, Ran, was significantly reduced in the replicative senescence, but not yet in SIPS, whereas nuclear import of actin by cofilin was already increased in SIPS. After treatment of young HDF cells with H2O2, rapid reduction of nuclear RanGTP was observed along with cytoplasmic increase of RanGDP. Furthermore, significantly reduced interaction of Exp6 with RanGTP was found by GST-Exp6 pull-down analysis. Failure of RanGTP restoration was accompanied with inhibition of ATP synthesis and NTF2 sequestration in the nuclei along with accordant change of senescence morphology. Indeed, knockdown of Exp6 expression significantly increased actin molecule in the nuclei of young HDF cells. Therefore, actin accumulation in nuclei of senescent cells is most likely due to the failure of RanGTP restoration with ATP deficiency and NTF2 accumulation in nuclei, which result in the decrease of actin export via Exp6 inactivation, in addition to actin import by cofilin activation.

  16. Spectrin-like proteins in plant nuclei

    NARCIS (Netherlands)

    Ruijter, de N.C.A.; Ketelaar, T.; Blumenthal, S.S.D.; Emons, A.M.C.; Schel, J.H.N.

    2000-01-01

    We analysed the presence and localization of spectrin-like proteins in nuclei of various plant tissues, using several anti-erythrocyte spectrin antibodies on isolated pea nuclei and nuclei in cells. Western blots of extracted purified pea nuclei show a cross-reactive pair of bands at 220–240 kDa, ty

  17. Two parametric cell cycle analyses of plant cell suspension cultures with fragile, isolated nuclei to investigate heterogeneity in growth of batch cultivations.

    Science.gov (United States)

    Haas, Christiane; Hegner, Richard; Helbig, Karsten; Bartels, Kristin; Bley, Thomas; Weber, Jost

    2016-06-01

    Plant cell suspensions are frequently considered to be heterogeneous with respect to growth in terms of progression of the cells through the cell cycle and biomass accumulation. Thus, segregated data of fractions in different cycle phases during cultivation is needed to develop robust production processes. Bromodeoxyuridine (BrdU) incorporation and BrdU-antibodies or 5-ethynyl-2'-deoxyuridine (EdU) click-it chemistry are frequently used to acquire such information. However, their use requires centrifugation steps that cannot be readily applied to sensitive cells, particularly if nuclei have to be extracted from the protective cellular milieu and envelopes for DNA analysis. Therefore, we have established a BrdU-Hoechst stain quenching protocol for analyzing nuclei directly isolated from delicate plant cell suspension cultures. After adding BrdU to test Harpagophytum procumbens cell suspension cultures the cell cycle distribution could be adequately resolved using its incorporation for the following 72 h (after which BrdU slowed biomass accumulation). Despite this limitation, the protocol allows resolution of the cell cycle distribution of cultures that cannot be analyzed using commonly applied methods due to the cells' fragility. The presented protocol enabled analysis of cycling heterogeneities in H. procumbens batch cultivations, and thus should facilitate process control of secondary metabolite production from fragile plant in vitro cultures. Biotechnol. Bioeng. 2016;113: 1244-1250. © 2015 Wiley Periodicals, Inc. PMID:26614913

  18. The correlation between uptake of methyl green and Feulgen staining intensity of cell nuclei. An image analysis study

    DEFF Research Database (Denmark)

    Lyon, H; Schulte, E; Hoyer, P E

    1989-01-01

    Paraffin sections of rat tissue fixed in either formaldehyde solution (3.6% w/v) or in Carnoy's fluid were stained using standardized Methyl Green-Pyronin procedures with the dyes used either simultaneously or in sequence. The sections were evaluated for the uptake of the two dyes by cell nuclei......, nucleoli and cytoplasm using colour TV-image analysis. The parameters measured were integrated optical density and the surface area of the object. The sections were then destained and a Feulgen reaction was performed. The coordinates of the cells measured after the simultaneous Methyl Green-Pyronin method...... were stored in the computer, making it possible to measure the same cells in the Feulgen-restained sections. Image analysis gave results which invalidate the sequential methods as opposed to the simultaneous method. Mean optical densities were significantly increased for both dyes with the simultaneous...

  19. Evaluation of epidermal growth factor interaction with cell surface and its accumulation in nuclei of lung carcinoma, epidermoid carcinoma and melanoma cell lines

    International Nuclear Information System (INIS)

    Specificity of binding to cell surface and nuclear accumulation of labelled epidermal growth factor (EGF) was investigated in lung carcinoma (A549), epidermoid carcinoma (HEp-2) and melanoma (B16) cell lines. It was demonstrated that the labelled EGF was bound specifically to the cell surface in line A549, HEp-2 and B16 cells; the latter exhibiting the lowest binding capacity and highest binding affinity. Comparison of nuclear accumulation of the labelled growth factor in these cell lines indicated, that melanoma cell line specifically accumulated the 125I-EGF in nuclei whereas A549 and HEp-2 did not. Thus, in order to evaluate the effect of EGF in various cells, a strict control of binding affinity and background binding is required. (author). 19 refs, 3 figs, 1 tab

  20. Modulation of Higher Order Chromatin Conformation in Mammalian Cell Nuclei Can Be Mediated by Polyamines and Divalent Cations.

    Directory of Open Access Journals (Sweden)

    Ashwat Visvanathan

    Full Text Available The organisation of the large volume of mammalian genomic DNA within cell nuclei requires mechanisms to regulate chromatin compaction involving the reversible formation of higher order structures. The compaction state of chromatin varies between interphase and mitosis and is also subject to rapid and reversible change upon ATP depletion/repletion. In this study we have investigated mechanisms that may be involved in promoting the hyper-condensation of chromatin when ATP levels are depleted by treating cells with sodium azide and 2-deoxyglucose. Chromatin conformation was analysed in both live and permeabilised HeLa cells using FLIM-FRET, high resolution fluorescence microscopy and by electron spectroscopic imaging microscopy. We show that chromatin compaction following ATP depletion is not caused by loss of transcription activity and that it can occur at a similar level in both interphase and mitotic cells. Analysis of both live and permeabilised HeLa cells shows that chromatin conformation within nuclei is strongly influenced by the levels of divalent cations, including calcium and magnesium. While ATP depletion results in an increase in the level of unbound calcium, chromatin condensation still occurs even in the presence of a calcium chelator. Chromatin compaction is shown to be strongly affected by small changes in the levels of polyamines, including spermine and spermidine. The data are consistent with a model in which the increased intracellular pool of polyamines and divalent cations, resulting from depletion of ATP, bind to DNA and contribute to the large scale hyper-compaction of chromatin by a charge neutralisation mechanism.

  1. Exotic nuclei

    International Nuclear Information System (INIS)

    The nuclei far from the β-stability valley which are referred to as exotic nuclei have attracted considerable interest in recent years. Undoubtedly the study of the exotic nuclei is destined to be one of the frontier fields in nuclear structure physics. The recent experiments with radioactive beams have opened up this new era in nuclear spectroscopy. The lighter exotic nuclei are observed to show quite interesting features. For example, a halo structure has been attributed to 11Li in order to explain the observed large matter radius. Also, it is seen that 31--33Na show deformed characteristics rather than the spherical shape expected from the shell closure at N = 20. This points towards a need for a new investigation of the shell structure as one moves away from the β - stability valley. With the aforementioned interesting features observed for the lighter nuclei, clearly one question of great interest is whether similar effects can be seen in heavy nuclei. New calculations using the relativistic mean field approach have been performed for a range of nuclei over a wide range of isotopes up to those with a large excess of neutrons. In the present talk, some interesting new results obtained from these calculations win be discussed

  2. Predictive variables for the biological behaviour of basal cell carcinoma of the face: relevance of morphometry of the nuclei.

    Science.gov (United States)

    Appel, T; Bierhoff, E; Appel, K; von Lindern, J-J; Bergé, S; Niederhagen, B

    2003-06-01

    We did a morphometric analysis of 130 histological sections of basal cell carcinoma (BCC) of the face to find out whether morphometric variables in the structure of the nuclei of BCC cells could serve as predictors of the biological behaviour. We considered the following variables: maximum and minimum diameters, perimeter, nuclear area and five form factors that characterise and quantify the shape of a structure (axis ratio, shape factor, nuclear contour index, nuclear roundness and circumference ratio). We did a statistical analysis of primary and recurring tumours and four histology-based groups (multifocal superficial BCCs, nodular BCCs, sclerosing BCCs and miscellaneous forms) using a two-sided t test for independent samples. Multifocal superficial BCCs showed significantly smaller values for the directly measured variables (maximum and minimum diameters, perimeter and nuclear area). Morphometry could not distinguish between primary and recurring tumours. PMID:12804537

  3. Retinal afferents synapse with relay cells targeting the middle temporal area in the pulvinar and lateral geniculate nuclei

    Directory of Open Access Journals (Sweden)

    Claire E Warner

    2010-02-01

    Full Text Available Considerable debate continues regarding thalamic inputs to the middle temporal area (MT of the visual cortex that bypass the primary visual cortex (V1 and the role they might have in the residual visual capability following a lesion of V1. Two specific retinothalamic projections to area MT have been speculated to relay through the medial portion of the inferior pulvinar nucleus (PIm and the koniocellular layers of the dorsal lateral geniculate nucleus (LGN. Although a number of studies have demonstrated retinal inputs to regions of the thalamus where relays to area MT have been observed, the relationship between the retinal terminals and area MT relay cells has not been established. Here we examined direct retino-recipient regions of the marmoset monkey (Callithrix jacchus pulvinar nucleus and the LGN following binocular injections of anterograde tracer, as well as area MT relay cells in these nuclei by injection of retrograde tracer into area MT. Retinal afferents were shown to synapse with area MT relay cells as demonstrated by colocalization with the presynaptic vesicle membrane protein synaptophysin. We also established the presence of direct synapes of retinal afferents on area MT relay cells within the PIm, as well as the koniocellular K1 and K3 layers of the LGN, thereby corroborating the existence of two disynaptic pathways from the retina to area MT that bypass V1.

  4. Evaluation of the areas of neuronal cell bodies and nuclei in the myenteric plexus of the duodenum of adult rats

    Directory of Open Access Journals (Sweden)

    MIRANDA-NETO MARCILÍO H.

    2000-01-01

    Full Text Available This study compared the areas of cell body and nucleus profiles of the myenteric neurons in the antimesenteric and intermediate regions of the duodenum of adult rats. Five male rats were used. The duodenum was removed and dissected to whole-mount preparations, which were stained by the Giemsa technique. The areas of cell body and nucleus profiles of 100 neurons, 50 from each region, of each animal, were assessed with image analyser. Based on the global mean±SD of the areas of cell body profiles, neurons were labelled as small, medium or large. It was observed that the neurons did not differ significantly in size or incidence between the antimesenteric and intermediate regions. However, the nuclei of the small and medium neurons were significantly smaller in the latter region. It is discussed that the smaller nuclear size could be related to the cell bodies being slightly smaller on this region and to a possible smaller biosynthetic activity which would influence nuclear size.

  5. Developmental potential of human oocytes reconstructed by transferring somatic cell nuclei into polyspermic zygote cytoplasm

    International Nuclear Information System (INIS)

    The generation of patient-specific nuclear transfer embryonic stem cells holds huge promise in modern regenerative medicine and cell-based drug discovery. Since human in vivo matured oocytes are not readily available, human therapeutic cloning is developing slowly. Here, we investigated for the first time whether human polyspermic zygotes could support preimplantation development of cloned embryos. Our results showed that polyspermic zygotes could be used as recipients for human somatic cell nuclear transfer (SCNT). The preimplantation developmental potential of SCNT embryos from polyspermic zygotes was limited to the 8-cell stage. Since ES cell lines can be derived from single blastomeres, these results may have important significance for human ES cells derived by SCNT. In addition, confocal images demonstrated that all of the SCNT embryos that failed to cleave showed abnormal microtubule organization. The results of the present study suggest that polyspermic human zygotes could be used as a potential source of recipient cytoplasm for SCNT.

  6. Developmental potential of human oocytes reconstructed by transferring somatic cell nuclei into polyspermic zygote cytoplasm

    Energy Technology Data Exchange (ETDEWEB)

    Fan, Yong; Chen, Xinjie; Luo, Yumei; Chen, Xiaolin; Li, Shaoying; Huang, Yulin [Institute of Gynecology and Obstetrics, The Third Affiliated Hospital of Guangzhou Medical College, Duobao Road 63, Guangzhou, Guangdong (China); Sun, Xiaofang, E-mail: xiaofangsun@hotmail.com [Institute of Gynecology and Obstetrics, The Third Affiliated Hospital of Guangzhou Medical College, Duobao Road 63, Guangzhou, Guangdong (China)

    2009-04-24

    The generation of patient-specific nuclear transfer embryonic stem cells holds huge promise in modern regenerative medicine and cell-based drug discovery. Since human in vivo matured oocytes are not readily available, human therapeutic cloning is developing slowly. Here, we investigated for the first time whether human polyspermic zygotes could support preimplantation development of cloned embryos. Our results showed that polyspermic zygotes could be used as recipients for human somatic cell nuclear transfer (SCNT). The preimplantation developmental potential of SCNT embryos from polyspermic zygotes was limited to the 8-cell stage. Since ES cell lines can be derived from single blastomeres, these results may have important significance for human ES cells derived by SCNT. In addition, confocal images demonstrated that all of the SCNT embryos that failed to cleave showed abnormal microtubule organization. The results of the present study suggest that polyspermic human zygotes could be used as a potential source of recipient cytoplasm for SCNT.

  7. Interferometric measurements of dry mass content in nuclei and cytoplasm in the life cycle of antheridial filaments cells of Chara vulgaris L. in their successive developmental stages

    Directory of Open Access Journals (Sweden)

    Hanna Kuran

    2015-05-01

    Full Text Available Interferometric measurements of the nucleus and cytoplasm dry mass during interphase in the successive stages of development of antheridial filaments of Chara vulgaris demonstrated that the dry mass and surface area of cell nuclei double in size in each of the successive generations of the filaments, whereas neither the surface nor the dry mass of the cytoplasm increase in such proportion in the same period. In the successive stages of development of the antheridial filaments the dry mass and surface area of the nuclei and cytoplasm gradually diminish.

  8. Kaonic nuclei

    Czech Academy of Sciences Publication Activity Database

    Mareš, Jiří; Friedman, E.; Gal, A.

    -, č. 56 (2006), s. 95-98. ISSN 0323-0465 R&D Projects: GA AV ČR IAA1048305 Institutional research plan: CEZ:AV0Z10480505 Keywords : key words * kaonic nuclei * Kbar-nucleus interactions Subject RIV: BE - Theoretical Physics Impact factor: 0.647, year: 2006

  9. Superdeformed nuclei

    International Nuclear Information System (INIS)

    Superdeformation was first proposed some twenty years ago to explain the fission isomers observed in some actinide nuclei. It was later realized that superdeformed shapes can occur at high angular momentum in lighter nuclei. The interest in the mechanisms responsible for these exotic shapes has increased enormously with the discovery of a superdeformed band of nineteen discrete lines in 152Dy (8). At about the same time, evidence for highly deformed nuclei (axis ratio 3:2) was also reported near 132Ce(9). Striking properties emerged from the first experiments, such as the essentially constant energy spacing between transitions (picket-fence spectra), the unexpectedly strong population of superdeformed bands at high spins, and the apparent lack of a link between the superdeformed states and the yrast levels. These findings were reviewed by Nolan and Twin. The present article follows upon their work and discusses the wealth of information that has since become available. This includes the discovery of a new island of superdeformation near A = 190, the detailed spectroscopy of ground and excited bands in the superdeformed well near A = 150 and A = 190, the surprising occurrence of superdeformed bands with identical transition energies in nuclei differing by one or two mass units, and the improved understanding of mechanisms responsible for the feeding into and the decay out of the superdeformed states

  10. Probing the compressibility of tumor cell nuclei by combined atomic force-confocal microscopy

    NARCIS (Netherlands)

    Krause, M.; Riet, J. te; Wolf, K. van der

    2013-01-01

    The cell nucleus is the largest and stiffest organelle rendering it the limiting compartment during migration of invasive tumor cells through dense connective tissue. We here describe a combined atomic force microscopy (AFM)-confocal microscopy approach for measurement of bulk nuclear stiffness toge

  11. Co-localisation studies of Arabidopsis SR splicing factors reveal different types of speckles in plant cell nuclei

    International Nuclear Information System (INIS)

    SR proteins are multidomain splicing factors which are important for spliceosome assembly and for regulation of alternative splicing. In mammalian nuclei these proteins localise to speckles from where they are recruited to transcription sites. By using fluorescent protein fusion technology and different experimental approaches it has been shown that Arabidopsis SR proteins, in addition to diffuse nucleoplasmic staining, localise into an irregular nucleoplasmic network resembling speckles in mammalian cells. As Arabidopsis SR proteins fall into seven conserved sub-families we investigated co-localisation of members of the different sub-families in transiently transformed tobacco protoplast. Here we demonstrate the new finding that members of different SR protein sub-families localise into distinct populations of nuclear speckles with no, partial or complete co-localisation. This is particularly interesting as we also show that these proteins do interact in a yeast two-hybrid assay as well as in pull-down and in co-immunopreciptiation assays. Our data raise the interesting possibility that SR proteins are partitioned into distinct populations of nuclear speckles to allow a more specific recruitment to the transcription/pre-mRNA processing sites of particular genes depending on cell type and developmental stage

  12. Magic nuclei

    International Nuclear Information System (INIS)

    4 nuclei of Nickel-48 have been produced in the GANIL accelerator. This nucleus is made up of 28 protons and 20 neutrons, it has at least 10 neutrons less than natural nickel but it is doubly magic: both protons and neutrons are distributed on full shells. It appears as if being doubly magic could compensate for the instability due to the shortage of neutrons. (A.C.)

  13. Spatial arrangement of genetic loci in human blood cell nuclei studied by confocal cytometry

    Czech Academy of Sciences Publication Activity Database

    Cafourková, Alena; Jirsová, Pavla; Kozubek, Stanislav; Kozubek, Michal; Bártová, Eva; Lukášová, Emilie

    Würzburg : University of Würzburg , 2001, s. P181. [International Chromosome Conference /14./. Würzburg (DE), 04.09.2001-08.09.2001] Institutional research plan: CEZ:AV0Z5004920 Keywords : genetic loci * human blood cell * confocal cytometry Subject RIV: BO - Biophysics

  14. The effects of accelerated heavy nuclei of neon and argon on mammalian cells in culture

    International Nuclear Information System (INIS)

    The survival of human T-1 kidney cells in high-energy neon (400MeV/nucleon) and argon (500MeV/nucleon) beams has been studied at the Berkeley Bevalac. Cells were plated in monolayers on glass and studied at different residual-range values. The survival curves depend on LET and on particle velocity. The effectiveness of the beams increases as the range decreases, except for argon beams with very low range values, where the effectiveness decreases again. The 'oxygen effect' is high at high particle energies (2.6 for neon and 2.4 for argon); it decreases to values between 1.1 and 1.3 near the Bragg peak. (author)

  15. Quantitative phosphoproteomics in nuclei of vasopressin-sensitive renal collecting duct cells

    OpenAIRE

    Bolger, Steven J.; Hurtado, Patricia A. Gonzales; Hoffert, Jason D.; Saeed, Fahad; Pisitkun, Trairak; Knepper, Mark A.

    2012-01-01

    Vasopressin regulates transport across the collecting duct epithelium in part via effects on gene transcription. Transcriptional regulation occurs partially via changes in phosphorylation of transcription factors, transcriptional coactivators, and protein kinases in the nucleus. To test whether vasopressin alters the nuclear phosphoproteome of vasopressin-sensitive cultured mouse mpkCCD cells, we used stable isotope labeling and mass spectrometry to quantify thousands of phosphorylation sites...

  16. Staining human lymphocytes and onion root cell nuclei with madder root.

    Science.gov (United States)

    Cücer, N; Guler, N; Demirtas, H; Imamoğlu, N

    2005-01-01

    We performed staining experiments on cells using natural dyes and different mordants using techniques that are used for wool and silk dyeing. The natural dye sources were madder root, daisy, corn cockle and yellow weed. Ferrous sulfate, copper sulfate, potassium tartrate, urea, potassium aluminum sulfate and potassium dichromate were used as mordants. Distilled water, distilled water plus ethanol, heptane, and distilled water plus methanol were used as solvents. All dye-mordant-solvent combinations were studied at pH 2.4, 3.2 and 4.2. The generic staining procedure was to boil 5-10 onion roots or stimulated human lymphocyte (SHL) preparations in a dye bath on a hot plate. Cells were examined at every half hour. For multicolor staining, madder-dyed lymphocytes were decolorized, then stained with Giemsa. The AgNOR technique was performed following the decolorization of Giemsa stained lymphocytes. Good results were obtained for both onion root cells and lymphocytes that were boiled for 3 h in a dye bath that included 4 g madder root, 4 g ferrous sulfate as mordant in 50 ml of 1:1 (v/v) methanol:distilled water. The pH was adjusted to 4.2 with 6 ml acetic acid. We conclude that madder root has potential as an alternative dye for staining biological materials. PMID:15804822

  17. Effects of hypergravity on the development of cell number and asymmetry in fish brain nuclei

    Science.gov (United States)

    Anken, R. H.; Werner, K.; Rahmann, H.

    Larval cichlid fish ( Oreochromis mossambicus) siblings were subjected to 3g hypergravity (hg) and total darkness for 21 days during development and subsequently processed for conventional histology. Further siblings reared at 1g and alternating light/dark (12h:12h) conditions served as contros. Cell number counts of the visual Nucleus isthmi (Ni) versus the vestibular Nucleus magnocellularis (Nm) revealed that in experimental animals total cell number was decreased in the Ni, possibly due to retarded growth as a result of the lack of visual input whereas no effect was observed in the Nm. Calculating the percentual asymmetry in cell number (i.e., right vs. the left side of the brain), no effects of hg/darkness were seen in the Ni, whereas asymmetry was slightly increased in the Nm. Since the asymmetry of inner ear otoliths is decreased under hg, this finding may indicate efferent vestibular action of the CNS on the level of the Nm by means of a feedback mechanism.

  18. BIX-01294 increases pig cloning efficiency by improving epigenetic reprogramming of somatic cell nuclei.

    Science.gov (United States)

    Huang, Jiaojiao; Zhang, Hongyong; Yao, Jing; Qin, Guosong; Wang, Feng; Wang, Xianlong; Luo, Ailing; Zheng, Qiantao; Cao, Chunwei; Zhao, Jianguo

    2016-01-01

    Accumulating evidence suggests that faulty epigenetic reprogramming leads to the abnormal development of cloned embryos and results in the low success rates observed in all mammals produced through somatic cell nuclear transfer (SCNT). The aberrant methylation status of H3K9me and H3K9me2 has been reported in cloned mouse embryos. To explore the role of H3K9me2 and H3K9me in the porcine somatic cell nuclear reprogramming, BIX-01294, known as a specific inhibitor of G9A (histone-lysine methyltransferase of H3K9), was used to treat the nuclear-transferred (NT) oocytes for 14-16 h after activation. The results showed that the developmental competence of porcine SCNT embryos was significantly enhanced both in vitro (blastocyst rate 16.4% vs 23.2%, P<0.05) and in vivo (cloning rate 1.59% vs 2.96%) after 50 nm BIX-01294 treatment. BIX-01294 treatment significantly decreased the levels of H3K9me2 and H3K9me at the 2- and 4-cell stages, which are associated with embryo genetic activation, and increased the transcriptional expression of the pluripotency genes SOX2, NANOG and OCT4 in cloned blastocysts. Furthermore, the histone acetylation levels of H3K9, H4K8 and H4K12 in cloned embryos were decreased after BIX-01294 treatment. However, co-treatment of activated NT oocytes with BIX-01294 and Scriptaid rescued donor nuclear chromatin from decreased histone acetylation of H4K8 that resulted from exposure to BIX-01294 only and consequently improved the preimplantation development of SCNT embryos (blastocyst formation rates of 23.7% vs 21.5%). These results indicated that treatment with BIX-01294 enhanced the developmental competence of porcine SCNT embryos through improvements in epigenetic reprogramming and gene expression. PMID:26604326

  19. Transcribed DNA is preferentially located in the perichromatin region of mammalian cell nuclei

    International Nuclear Information System (INIS)

    The precise localization of transcribed DNA and resulting RNA is an important aspect of the functional architecture of the nucleus. To this end we have developed a novel in situ hybridization approach in combination with immunoelectron microscopy, using sense and anti-sense RNA probes that are derived from total cellular or cytoplasmic poly(A+) RNA. This new technology is much more gentle than classical in situ hybridization using DNA probes and shows excellent preservation of nuclear structure. Carried out on ultrathin sections of fixed and resin-embedded COS-7 cells, it revealed at high resolution the localization of the genes that code for the cellular mRNAs. Quantitative analysis shows that most transcribed DNA is concentrated in the perichromatin region, i.e. the interface between subchromosomal compact chromatin domains and the interchromatin space essentially devoid of DNA. The RNA that is produced is found mainly in the perichromatin region and the interchromatin space. These results imply that in the mammalian nucleus the chromatin fiber is folded so that active genes are predominantly present in the perichromatin region, which is the most prominent site of transcription.

  20. Characterization of biological ice nuclei from a lichen.

    OpenAIRE

    Kieft, T. L.; Ruscetti, T

    1990-01-01

    Biological ice nuclei (active at approximately -4 degrees C) were extracted from cells of the lichen Rhizoplaca chrysoleuca by sonication. Sensitivity to proteases, guanidine hydrochloride, and urea showed these nuclei to be proteinaceous. The nuclei were relatively heat stable, active from pH 1.5 to 12, and active without lipids, thereby demonstrating significant differences from bacterial ice nuclei.

  1. Transport of Β-globin mRNA from nuclei of friend erythroleukemia cells - Reversible redox-dependent inhibition of mRNA transport

    International Nuclear Information System (INIS)

    An in vitro assay system for routine analysis of the release of Β-globin mRNA from isolated nuclei of Friend erythroleukemia cells is described. By direct blotting of the released material, hybridization and densitometric scanning of the autoradiographs, the rate of mRNA release was quantified. The degradation of mRNA was prevented by addition of the placental ribonuclease inhibitor RNasin to the incubation medium. The oxidizing sulfhydryl reagent o-iodosobenzoate, in contrast to the non-oxidizing reagent iodoacetate, inhibited Β-globin mRNA transport from the isolated nuclei. The inhibition could be reversed by the reducing agent dithiothreitol indicating that mRNA transport is affected by thiol-disulfide conversions. This observation might be useful for further elucidation of the basic mechanism of RNA transport

  2. Isolation of mRNA and a cell free protein synthesizing system for the synthesis of amidating enzyme from the nuclei of gamma irradiated potato buds

    International Nuclear Information System (INIS)

    mRNA required for the synthesis of amidating enzyme in the nuclear fraction of γ-irradiated potato buds, has been isolated using poly (U) sepharose 4B affinity chromatography, and sucrose density gradient centrifugation. A cell-free protein synthesizing system has been obtained from the irradiated potato bud nuclei, capable of in vitro synthesis of this enzyme protein in the presence of mRNA. Unirradiated bud tissue nuclei does not contain the mRNA for this protein. mRNA isolated can also be translated with wheat germ system to give the amidating enzyme. Separation of this mRNA on 5-20% sucrose density gradient shows that mRNA amidating enzyme is 9S type. (auth.)

  3. Setup with Laser Ionization in Gas Cell for Production and Study of Neutron-Rich Heavy Nuclei

    Science.gov (United States)

    Zagrebaev, V. I.; Zemlyanoy, S. G.; Kozulin, E. M.; Kudryavtsev, Yu.; Fedosseev, V.; Bark, R.; Janas, Z.; Othman, H. A.

    2015-11-01

    The present limits of the upper part of the nuclear map are very close to stability while the unexplored area of heavy neutron-rich nuclides along the neutron closed shell N=126 is extremely important for nuclear astrophysics investigations and, in particular, for the understanding of the r-process of astrophysical nucleosynthesis. This area of the nuclear map can be reached neither in fusion-fission reactions nor in fragmentation processes widely used nowadays for the production of exotic nuclei. A new way was recently proposed for the production of these nuclei via low-energy multi-nucleon transfer reactions. The estimated yields of neutron-rich nuclei are found to be significantly high in such reactions and several tens of new nuclides can be produced, for example, in the near-barrier collision of 136Xe with 208Pb. A new setup is proposed to produce and study heavy neutron-rich nuclei located along the neutron closed shell N=126.

  4. Detection of intranuclear forces by the use of laser optics during the recovery process of elongated interphase nuclei in centrifuged protonemal cells of Adiantum capillus-veneris

    International Nuclear Information System (INIS)

    For the direct investigation of intranuclear dynamics in living cells, extremely deformed nuclei of basipetally centrifuged protonemal cells of the fern Adiantum capillusveneris were manipulated by the laser rap and the laser scalpel. Whereas the nucleolus was tightly fixed at the central position inside the non-centrifuged nucleus and proved to be immovable by the optical trap, it could easily be trapped and moved towards three directions inside the bubble-like terminal widening of the basal thread-like extension of centrifuged nuclei. Due to the connection of the nucleolus to the chromatin inside the nuclear thread (NT), moving was not possible against the direction of the nuclear apical main body. Nucleoli in recovered nuclei were again immovable, thus indicating the presence of a dynamic nucleolar anchoring system inside the nucleus. When the nucleolus in the bubble was arrested during the thread shortening process by the optical trap, the acropetal movement of the bubble continued. Probably dye to dragging forces, some nucleoli became stretched, and a thick strand of a still unknown composition stretched between the nucleolus and the insertion site of the shortening NT. To assess whether the shrinking of the nuclear envelop (NE) and the shortening of the chromatin inside the NT were independent processes, the chromatin above the bubble was cut inside the Nt by the laser scalpel. After severance, a gap between the nucleolus and the end of the chromatin strand in the NT indicated the shortening of the chromatin inside the Nt. From these findings it was concluded that a shortening force was existing in the chromatin of the NT and that probably no physical link existed between the chromatin and the NE

  5. Shape-based nuclei area of digitized pap smear images

    Science.gov (United States)

    Muhimmah, Izzati; Kurniawan, Rahadian

    2012-04-01

    Nuclei of the epithelial of Pap smear cells are important risk indicator of cervical cancers. Pathologist uses the changing of the area of the nuclei to determine whether cells are normal or abnormal. It means that having correct measurement of the area of nuclei is important on the pap smears assessment. Our paper present a novel approach to analyze the shape of nuclei in pap smear images and measuring the area of nuclei. We conducted a study to measure the area of nuclei automatically by calculating the number of pixels contained in each of the segmented nuclei. For comparison, we performed measurements of nuclei area using the ellipse area approximation. The result of the t-test confirmed that there were similarity between elliptical area approximation and automatic segmented nuclei-area at 0.5% level of significance.

  6. Kinetics of H3-thymidine incorporation into nuclei of cells of the regenerating liver of rats exposed to various doses of X-rays

    International Nuclear Information System (INIS)

    Action of X-radiation on the incorporation of H3-thymidine into nuclei of cells of the regenerating liver of rats has been studied. A whole-body exposure of rats to 150-300 R has been found to inhibit H3-thymidine uptake into DNA of S-cells of the regenerating liver, and this effect can be attributed to the inhibition of DNA synthesis rather than to changes in the concentration of a label in the intracellular pool of DNA precursors. In addition to the DNA synthesis decrease, inhibition of the label uptake into the pool is observed after doses of 600 to 1200 R. On the basis of the data obtained, a hypothesis is proposed that explains the mechanism of inhibition of DNA synthesis under the action of radiation

  7. Isobar excitations in nuclei

    International Nuclear Information System (INIS)

    This paper covers the following aspects of isobar excitations in nuclei: Nuclear spin response; Electromagnetic probes; Pion-nuclear reactions; Baryon charge exchange reactions; Charge exchange reactions on nuclei; and Exclusive spectra

  8. Moringa oleifera Lam. seed extract prevents fat diet induced oxidative stress in mice and protects liver cell-nuclei from hydroxyl radical mediated damage.

    Science.gov (United States)

    Das, Nilanjan; Ganguli, Debdutta; Dey, Sanjit

    2015-12-01

    High fat diet (HFD) prompts metabolic pattern inducing reactive oxygen species (ROS) production in mitochondria thereby triggering multitude of chronic disorders in human. Antioxidants from plant sources may be an imperative remedy against this disorder. However, it requires scientific validation. In this study, we explored if (i) Moringa oleifera seed extract (MoSE) can neutralize ROS generated in HFD fed mice; (ii) protect cell-nuclei damage developed by Fenton reaction in vitro. Swiss mice were fed with HFD to develop oxidative stress model (HFD group). Other groups were control, seed extract alone treated, and MoSE simultaneously (HS) treated. Treatment period was of 15 days. Antioxidant enzymes with tissue nitrite content (TNC) and lipid peroxidation (LPO) were estimated from liver homogenate. HS group showed significantly higher (P antioxidant power (FRAP) compared to only HFD fed group. Further, TNC and LPO decreased significantly (P antioxidant prospective to neutralize ROS developed in HFD fed mice and also protected the nuclei damage from hydroxyl radicals. Hence, it can be used as herbal medication against HFD induced ROS mediated disorders. PMID:26742324

  9. 3D reconstruction of VZV infected cell nuclei and PML nuclear cages by serial section array scanning electron microscopy and electron tomography.

    Directory of Open Access Journals (Sweden)

    Mike Reichelt

    Full Text Available Varicella-zoster virus (VZV is a human alphaherpesvirus that causes varicella (chickenpox and herpes zoster (shingles. Like all herpesviruses, the VZV DNA genome is replicated in the nucleus and packaged into nucleocapsids that must egress across the nuclear membrane for incorporation into virus particles in the cytoplasm. Our recent work showed that VZV nucleocapsids are sequestered in nuclear cages formed from promyelocytic leukemia protein (PML in vitro and in human dorsal root ganglia and skin xenografts in vivo. We sought a method to determine the three-dimensional (3D distribution of nucleocapsids in the nuclei of herpesvirus-infected cells as well as the 3D shape, volume and ultrastructure of these unique PML subnuclear domains. Here we report the development of a novel 3D imaging and reconstruction strategy that we term Serial Section Array-Scanning Electron Microscopy (SSA-SEM and its application to the analysis of VZV-infected cells and these nuclear PML cages. We show that SSA-SEM permits large volume imaging and 3D reconstruction at a resolution sufficient to localize, count and distinguish different types of VZV nucleocapsids and to visualize complete PML cages. This method allowed a quantitative determination of how many nucleocapsids can be sequestered within individual PML cages (sequestration capacity, what proportion of nucleocapsids are entrapped in single nuclei (sequestration efficiency and revealed the ultrastructural detail of the PML cages. More than 98% of all nucleocapsids in reconstructed nuclear volumes were contained in PML cages and single PML cages sequestered up to 2,780 nucleocapsids, which were shown by electron tomography to be embedded and cross-linked by an filamentous electron-dense meshwork within these unique subnuclear domains. This SSA-SEM analysis extends our recent characterization of PML cages and provides a proof of concept for this new strategy to investigate events during virion assembly at the

  10. Herpes simplex virus-1 infection or Simian virus 40-mediated immortalization of corneal cells causes permanent translocation of NLRP3 to the nuclei

    Directory of Open Access Journals (Sweden)

    Shu-Long Wang

    2015-01-01

    Full Text Available AIM: To investigate into the potential involvement of pyrin containing 3 gene (NLRP3, a member of the nucleotide-binding oligomerization domain-like receptors with cytosolic pattern recognition, in the host defense of corneas against viruses. METHODS: The herpes viral keratitis model was utilized in BALB/c mice with inoculation of herpes simplex virus-1 (HSV-1. Corneal tissues removed during therapy of patients with viral keratitis as well as a Simian vacuolating virus 40 (SV40-immortalized human corneal epithelial cell line were also examined. Immunohistochemistry was used to detect NLRP3 in these subjects, focusing on their distribution in tissue or cells. Western blot was used to measure the level of NLRP3 and another two related molecules in NLPR3 inflammasome, namely caspase-1 and IL-1β. RESULTS: The NLRP3 activation induced by HSV-1 infection in corneas was accompanied with redistribution of NLRP3 from the cytoplasm to the nucleus in both murine and human corneal epithelial cells. Furthermore, in the SV40-immortalized human corneal epithelial cells, NLRP3 was exclusively located in the nucleus, and treatment of the cells with high concentration of extracellular potassium (known as an inhibitor of NLRP3 activation effectively drove NLRP3 back to the cytoplasm as reflected by both immunohistochemistry and Western blot. CONCLUSION: It is proposed that herpes virus infection activates and causes redistribution of NLRP3 to nuclei. Whether this NLRP3 translocation occurs with other viral infections and in other cell types merit further study.

  11. Use antibodies to DNA for detection of X-ray impairments of DNA in nuclei of brain stem cells of irradiated animals

    International Nuclear Information System (INIS)

    Using antibodies to DNA, impairments of DNA in nuclei of brain stem cells were studied in white male-rats at early stages after X-ray irradiation. Irradiation doses were 25.8, 103.2, 154.8, 206.4 and 258 m Coul/kg. Only at 258 m Coul/kg dose the complete repair of immunofluorescent cells percentage up to the level of intact animals was observed 1h after irradiation. The complete repair at 103.2 m Coul/kg dose occured 3h after the irradiation. The lethal doses (206.4 - 258 m Coul/kg) caused such DNA impairments which were not reduced even 3h after the irradiation of the animals. Thus, it is shown that the immunological method can be useful for studying DNA structural impairments in the range of 25.8-258 m Coul/kg doses. The method permits to test DNA radiation damages without its extraction from the cell

  12. Incorporation of thymidine into onion root meristematic cell nuclei in presence of hydroxyurea and its role in recovery of mitotic activity

    International Nuclear Information System (INIS)

    Hydroxyurea treatment of onion roots induced mitotic block which was released by transfer of bulbs to water, and also to some extent by addition of cold or 3H-thymidine to hydroxyurea solutions. In presence of hydroxyurea there was noted very intense incorporation of 3H-thymidine into cell nuclei, giving labelling index of 40-70%. However, all the mitotic figures appearing in presence of hydroxyurea and 3H-thymidine were unlabelled. On the other hand, labelled mitotic figures were obtained when roots incubated with 3H-thymidine in presence of hydroxyurea had been transferred to water. Incorporation of 3H-uridine was unaffected by hydroxyurea. The results show that hydroxyurea arrests onion root meristematic cells, either in the S phase and the G2 phase. Enhanced incorporation of 3H-thymidine in the presence of hydroxyurea, and release by added thymidine of the mitotic block indicate that hydroxyurea induces in onion root meristematic cells a particular shortage of thymidylate. (author)

  13. Use antibodies to DNA for detection of X-ray impairments of DNA in nuclei of brain stem cells of irradiated animals

    Energy Technology Data Exchange (ETDEWEB)

    Mitryaeva, N.A.; Moskalenko, I.P.

    1981-01-01

    Using antibodies to DNA, impairments of DNA in nuclei of brain stem cells were studied in white male-rats at early stages after X-ray irradiation. Irradiation doses were 25.8, 103.2, 154.8, 206.4 and 258 m Coul/kg. Only at 258 m Coul/kg dose the complete repair of immunofluorescent cells percentage up to the level of intact animals was observed 1h after irradiation. The complete repair at 103.2 m Coul/kg dose occured 3h after the irradiation. The lethal doses (206.4 - 258 m Coul/kg) caused such DNA impairments which were not reduced even 3h after the irradiation of the animals. Thus, it is shown that the immunological method can be useful for studying DNA structural impairments in the range of 25.8-258 m Coul/kg doses. The method permits to test DNA radiation damages without its extraction from the cell.

  14. Modeling of the topology of energy deposits created by ionizing radiation on a nano-metric scale in cell nuclei in relation to radiation-induced early events

    International Nuclear Information System (INIS)

    Ionizing radiations are known to induce critical damages on biological matter and especially on DNA. Among these damages, DNA double strand breaks (DSB) are considered as key precursor of lethal effects of ionizing radiations. Understand and predict how DNA double and simple strand breaks are created by ionizing radiation and repaired in cell nucleus is nowadays a major challenge in radiobiology research. This work presents the results on the simulation of the DNA double strand breaks produced from the energy deposited by the irradiation at the intracellular level. At the nano-metric scale, the only method to accurately simulate the topological details of energy deposited on the biological matter is the use of Monte Carlo codes. In this work, we used the Geant4 Monte Carlo code and, in particular, the low energy electromagnetic package extensions, referred as Geant4-DNA processes.In order to evaluate DNA radio-induced damages, the first objective of this work consisted in implementing a detailed geometry of the DNA on the Monte Carlo simulations. Two types of cell nuclei, representing a fibroblast and an endothelium, were described in order to evaluate the influence of the DNA density on the topology of the energy deposits contributing to strand breaks. Indeed, the implemented geometry allows the selection of energy transfer points that can lead to strand breaks because they are located on the backbone. Then, these energy transfer points were analysed with a clustering algorithm in order to reveal groups of aggregates and to study their location and complexity. In this work, only the physical interactions of ionizing radiations are simulated. Thus, it is not possible to achieve an absolute number of strand breaks as the creation and transportation of radical species which could lead to indirect DNA damages is not included. Nevertheless, the aim of this work was to evaluate the relative dependence of direct DNA damages with the DNA density, radiation quality, cell

  15. Nuclei and quantum worlds

    International Nuclear Information System (INIS)

    This document gathers the slides and their commentaries that have been presented at the conference 'physics and fundamental questions' by P. Chomaz. The author reviews the different quantum aspects of nuclei: tunnel effect, symmetries, magic numbers, wave functions, size, shapes and deformations. The author shows that nuclei are quantum objects of great complexity, their structures are not yet well understood and the study of exotic nuclei will continue bringing valuable information

  16. Neutron rich nuclei

    International Nuclear Information System (INIS)

    If some β- emitters are particularly interesting to study in light, medium, and heavy nuclei, another (and also) difficult problem is to know systematically the properties of these neutron rich nuclei far from the stability line. A review of some of their characteristics is presented. How far is it possible to be objective in the interpretation of data is questioned and implications are discussed

  17. Nuclei in high forms

    International Nuclear Information System (INIS)

    The purpose of 1991 Joliot-Curie Summer School is to review the most advances in the understanding of the nuclei physics after the considerable progress in gamma spectroscopy. It covers the following topics: Highly and super-deformed nuclei, nuclear structures, mean-field approach and beyond, fission isomers, nuclear excitations with long lifetime and metal clusters

  18. Effect of local UV irradiation of generative nuclei of Paramecium caudatum on sexual functions of the cells

    International Nuclear Information System (INIS)

    The functions of micronucleus (MI) were studied in the period of the sexual process in Paramecium caudatum-infusoria the descendants of the cells, whose micronucleus was locally irradiated with UV rays at the dose of 3060 erg/mm2. It has been found that the descendants of the irradiated cells (the cells of UV clones) can be involved into the sexual process irrespoctive of the morphological type of their MI. Four out of forteen UV clones have changed the initial mating type for the opposite one. It is suggested that the change of the mating type is related to the changes of MI genome resulted from UV irradiation. The pathway of nuclear transformations in the course of sexual process was traced in cells of three UV clones. It has been found, that local UV irradiation of MI causes a number of deviations in the behaviour of MI derivatives in the metagamic part of the sexual process in the clones, whose MI have undergone substantial morphological changes. The exconjugants produced by crossing of UV clones with such changed MI and the normal test-clone were characterized by low viability

  19. Identification of poly(ADP-ribose) polymerase-1 as the OXPHOS-generated ATP sensor of nuclei of animal cells

    International Nuclear Information System (INIS)

    Our results show that in the intact normal animal cell mitochondrial ATP is directly connected to nuclear PARP-1 by way of a specific adenylate kinase enzymatic path. This mechanism is demonstrated in two models: (a) by its inhibition with a specific inhibitor of adenylate kinase, and (b) by disruption of ATP synthesis through uncoupling of OXPHOS. In each instance the de-inhibited PARP-1 is quantitatively determined by enzyme kinetics. The nuclear binding site of PARP-1 is Topo I, and is identified as a critical 'switchpoint' indicating the nuclear element that connects OXPHOS with mRNA synthesis in real time. The mitochondrial-nuclear PARP-1 pathway is not operative in cancer cells

  20. Complementary Assays Reveal a Low Level of CA Associated with Viral Complexes in the Nuclei of HIV-1-Infected Cells

    OpenAIRE

    Hulme, Amy E.; Kelley, Z; Foley, Deirdre; Hope, Thomas J.

    2015-01-01

    During uncoating, the conical capsid of HIV disassembles by dissociation of the p24 capsid protein (CA). Uncoating is known to be required for HIV replication, but the mechanism is poorly defined. Here, we examined the timing and effect of two capsid binding drugs (PF74 and BI2) on infectivity and capsid integrity in HIV-1-infected cells. The virus remained susceptible to the action of PF74 and BI2 for hours after uncoating as defined in parallel drug addition and cyclosporine (CsA) washout a...

  1. Strain differences in pH-sensitive K+ channel-expressing cells in chemosensory and nonchemosensory brain stem nuclei

    OpenAIRE

    Martino, Paul F.; Olesiak, S.; Batuuka, D.; Riley, D; Neumueller, S.; Forster, H. V.; Hodges, M. R.

    2014-01-01

    The ventilatory CO2 chemoreflex is inherently low in inbred Brown Norway (BN) rats compared with other strains, including inbred Dahl salt-sensitive (SS) rats. Since the brain stem expression of various pH-sensitive ion channels may be determinants of the CO2 chemoreflex, we tested the hypothesis that there would be fewer pH-sensitive K+ channel-expressing cells in BN relative to SS rats within brain stem sites associated with respiratory chemoreception, such as the nucleus tractus solitarius...

  2. Nucleons in nuclei, however

    International Nuclear Information System (INIS)

    The topics presented at the 1989 Joliot-Curie Lectures are reported. Two main subjects were retained: a simplified description of the N-body motion of particles in the quasi-particle configuration; study of the dynamics of nuclear components which are not described by nucleons in their ground state. The following themes were presented: quasiparticles and the Green functions, relativistic aspects of the quasiparticle concept, the dimensions of nucleons in the nuclei and the EMC effect, quarks and gluons in the nuclei, the delta in the nuclei, the strangeness, quasiparticles far from the Fermi sea, diffusion of electrons, stellar evolution and nucleosynthesis

  3. Coulomb energy of nuclei

    International Nuclear Information System (INIS)

    The density functional determining the Coulomb energy of nuclei is calculated to the first order in e2. It is shown that the Coulomb energy includes three terms: the Hartree energy; the Fock energy; and the correlation Coulomb energy (CCE), which contributes considerably to the surface energy, the mass difference between mirror nuclei, and the single-particle spectrum. A CCE-based mechanism of a systematic shift of the single-particle spectrum is proposed. A dominant contribution to the CCE is shown to come from the surface region of nuclei. The CCE effect on the calculated proton drip line is examined, and the maximum charge Z of nuclei near this line is found to decrease by 2 or 3 units. The effect of Coulomb interaction on the effective proton mass is analyzed

  4. Coulomb Energy of Nuclei

    CERN Document Server

    Shaginyan, V R

    2001-01-01

    The density functional determining the Coulomb energy of nuclei is calculated to the first order in $e^2$. It is shown that the Coulomb energy includes three terms: the Hartree energy; the Fock energy; and the correlation Coulomb energy (CCE), which contributes considerably to the surface energy, the mass difference between mirror nuclei, and the single-particle spectrum. A CCE-based mechanism of a systematic shift of the single-particle spectrum is proposed. A dominant contribution to the CCE is shown to come from the surface region of nuclei. The CCE effect on the calculated proton drip line is examined, and the maximum charge $Z$ of nuclei near this line is found to decrease by 2 or 3 units. The effect of Coulomb interaction on the effective proton mass is analyzed.

  5. Coulomb Energy of Nuclei

    OpenAIRE

    Shaginyan, V. R.

    2002-01-01

    The density functional determining the Coulomb energy of nuclei is calculated to the first order in $e^2$. It is shown that the Coulomb energy includes three terms: the Hartree energy; the Fock energy; and the correlation Coulomb energy (CCE), which contributes considerably to the surface energy, the mass difference between mirror nuclei, and the single-particle spectrum. A CCE-based mechanism of a systematic shift of the single-particle spectrum is proposed. A dominant contribution to the CC...

  6. Hot nuclei and fragmentation

    International Nuclear Information System (INIS)

    A review is made of the present status concerning the production of nuclei above 5 MeV temperature. Considerable progress has been made recently on the understanding of the formation and the fate of such hot nuclei. It appears that the nucleus seems more stable against temperature than predicted by static calculations. However, the occurrence of multifragment production at high excitation energies is now well established. The various experimental features of the fragmentation process are discussed. (author) 59 refs., 12 figs

  7. Electroweak interactions in nuclei

    Science.gov (United States)

    Henley, E. M.

    1984-06-01

    Nuclear and subnuclear degrees of freedom and lepton nucleus scattering were discussed. Electroweak interactions in nuclei were examined. Topics discussed include: introduction to electroweak theory; the Weinberg-Salam theory for leptons; the Weinberg-Salam theory for hadrons-the GIM mechanism; electron scattering as a probe of the electroweak interaction (observation of PV, the weak interaction for nucleons, and parity violation in atoms); and time reversed invariance and electric dipole moments of nucleons, nuclei, and atoms.

  8. Physics of Unstable Nuclei

    Science.gov (United States)

    Khoa, Dao Tien; Egelhof, Peter; Gales, Sydney; Giai, Nguyen Van; Motobayashi, Tohru

    2008-04-01

    Studies at the RIKEN RI beam factory / T. Motobayashi -- Dilute nuclear states / M. Freer -- Studies of exotic systems using transfer reactions at GANIL / D. Beaumel et al. -- First results from the Magnex large-acceptance spectrometer / A. Cunsolo et al. -- The ICHOR project and spin-isospin physics with unstable beams / H. Sakai -- Structure and low-lying states of the [symbol]He exotic nucleus via direct reactions on proton / V. Lapoux et al. -- Shell gap below [symbol]Sn based on the excited states in [symbol]Cd and [symbol]In / M. Górska -- Heavy neutron-rich nuclei produced in the fragmentation of a [symbol]Pb beam / Zs. Podolyák et al. -- Breakup and incomplete fusion in reactions of weakly-bound nuclei / D.J. Hinde et al. -- Excited states of [symbol]B and [symbol]He and their cluster aspect / Y. Kanada-En'yo et al. -- Nuclear reactions with weakly-bound systems: the treatment of the continuum / C. H. Dasso, A. Vitturi -- Dynamic evolution of three-body decaying resonances / A. S. Jensen et al. -- Prerainbow oscillations in [symbol]He scattering from the Hoyle state of [symbol]C and alpha particle condensation / S. Ohkubo, Y. Hirabayashi -- Angular dispersion behavior in heavy ion elastic scattering / Q. Wang et al. -- Microscopic optical potential in relativistic approach / Z.Yu. Ma et al. -- Exotic nuclei studied in direct reactions at low momentum transfer - recent results and future perspectives at fair / P. Egelhof -- Isotopic temperatures and symmetry energy in spectator fragmentation / M. De Napoli et al. -- Multi-channel algebraic scattering theory and the structure of exotic compound nuclei / K. Amos et al. -- Results for the first feasibility study for the EXL project at the experimental storage ring at GSI / N. Kalantar-Nayestanaki et al. -- Coulomb excitation of ISOLDE neutron-rich beams along the Z = 28 chain / P. Van Duppen -- The gamma decay of the pygmy resonance far from stability and the GDR at finite temperature / G. Benzoni et al

  9. Particles and nuclei, letters

    International Nuclear Information System (INIS)

    The present collection of letters from JINR, Dubna, contains seven separate records on kinematic separation and mass analysis of heavy recoiling nuclei, dynamical effects prior to heavy ion fusion, VACTIV-DELPHI graphical dialog based program for the analysis of gamma-ray spectra, irradiation of nuclear emulsions in relativistic beams of 6He and3H nuclei, optical and structural investigations of PLZT x/65/35 (x = 4, 8 %) ferroelectric ceramics irradiated by a high-current pulsed electron beam, the oscillating charge and first evidence for neutrinoless double beta decay

  10. Particles and nuclei, letters

    International Nuclear Information System (INIS)

    The present collection of letters from JINR, Dubna, contains seven separate records on physics from extra dimensions, new physics in the new millennium with GENIUS: double beta decay, dark matter, solar neutrinos, the (μ-, e+) conversion in nuclei mediated by light Majorana neutrinos, exotic muon-to-positron conversion in nuclei: partial transition sum evaluation by using shell model, solar neutrino problem accounting for self consistent magnetohydrodynamics solution for solar magnetic fields, first neutrino observations from the Sudbury neutrino observatory and status report on BOREXINO and results of the muon-background measurements at CERN

  11. Rotational motion in nuclei

    International Nuclear Information System (INIS)

    Nuclear structure theories are reviewed concerned with nuclei rotational motion. The development of the deformed nucleus model facilitated a discovery of rotational spectra of nuclei. Comprehensive verification of the rotational scheme and a successful classification of corresponding spectra stimulated investigations of the rotational movement dynamics. Values of nuclear moments of inertia proved to fall between two marginal values corresponding to rotation of a solid and hydrodynamic pattern of an unrotating flow, respectively. The discovery of governing role of the deformation and a degree of a symmetry violence for determining rotational degrees of freedon is pointed out to pave the way for generalization of the rotational spectra

  12. Interactions on Nuclei

    OpenAIRE

    Hoyer, Paul

    1995-01-01

    I review hard photon initiated processes on nuclei. The space-time development of the DIS reaction as viewed in the target rest frame qualitatively describes the nuclear shadowing of quark and gluon distributions, although it may be difficult to understand the very weak $Q^2$ dependence of the low $x$ data. The current jet hadron energy distribution at large $\

  13. Electroweak interactions in nuclei

    International Nuclear Information System (INIS)

    Topics include: introduction to electroweak theory; the Weinberg-Salam theory for leptons; the Weinberg-Salam theory for hadrons-the GIM mechanism; electron scattering as a probe of the electroweak interaction (observation of PV, the weak interaction for nucleons, and parity violation in atoms); and time reversed invariance and electric dipole moments of nucleons, nuclei, and atoms. 52 references

  14. Nuclei with tetrahedral symmetry

    International Nuclear Information System (INIS)

    We discuss a point-group-theory based method of searching for new regions of nuclear stability. We illustrate the related strategy with realistic calculations employing the tetrahedral and the octahedral point groups. In particular, several nuclei in the rare earth region appear as excellent candidates to study the new mechanism. (author)

  15. Octupole collectivity in nuclei

    Science.gov (United States)

    Butler, P. A.

    2016-07-01

    The experimental and theoretical evidence for octupole collectivity in nuclei is reviewed. Recent theoretical advances, covering a wide spectrum from mean-field theory to algebraic and cluster approaches, are discussed. The status of experimental data on the behaviour of energy levels and electric dipole and electric octupole transition moments is reviewed. Finally, an outlook is given on future prospects for this field.

  16. Triaxiality in superheavy nuclei

    International Nuclear Information System (INIS)

    In this work, triaxial degree of freedom is explicitly utilized in calculating alpha decay lifetimes. The synthesis of superheavy nuclei with Z = 114-116 and 118 were detected by their decaying alpha chains with terminating spontaneous fission events. The lifetime of alpha decay chains measured are to be compared with the values evaluated theoretically

  17. Fissibility of compound nuclei

    CERN Document Server

    Iwata, Yoritaka

    2012-01-01

    Collisions between $^{248}$Cm and $^{48}$Ca are systematically investigated by time-dependent density functional calculations with evaporation prescription. Depending on the incident energy and impact parameter, fusion, deep-inelastic and fission events are expected to appear. In this paper, a microscopic method of calculating the fissibility of compound nuclei is presented.

  18. Disintegration of comet nuclei

    International Nuclear Information System (INIS)

    The breaking up of comets into separate pieces, each with its own tail, was seen many times by astronomers of the past. The phenomenon was in sharp contrast to the idea of the eternal and unchangeable celestial firmament and was commonly believed to be an omen of impending disaster, especially for comets with tails stretching across half the sky. It is only now that we have efficient enough space exploration tools to see comet nuclei and even - in the particular case of small comet Hartley-2 in 2010 - to watch their disintegration stage. There are also other suspected candidates for disintegration in the vast family of comet nuclei and other Solar System bodies. (physics of our days)

  19. Bubble nuclei; Noyaux Bulles

    Energy Technology Data Exchange (ETDEWEB)

    Legoll, F. [Service de Physique Theorique, CEA Centre d`Etudes de Saclay, 91 - Gif-sur-Yvette (France)

    1998-07-22

    For nuclei with very high electrical charge, the Coulomb field is expected to drive the protons away from the centre to the surface of the nucleus. Such a nucleus would be no more compact but look like a bubble. The goal of this work is to confirm this idea. We are interested in only the ground state of spherical nuclei. We use the Skyrme potential with the Sly4 parametrization to calculate the mean-field Hamiltonian. Paring correlations are described by a surface-active delta paring interaction. In its ground state the nucleus {sup A=900} X{sub Z=274} is shown to be a bubble. Another stable state is found with a little higher energy: it is also a bubble. (author) 11 refs., 18 figs., 33 tabs.

  20. Nuclei in the Cosmos

    International Nuclear Information System (INIS)

    Nuclei in the Cosmos is the foremost bi-annual conference of nuclear physicists, astrophysicists, cosmochemists, and others to survey the recent achievements in Nuclear Astrophysics. As an interdisciplinary meeting it promotes mutual understanding and collaboration over fields fundamental to solve a range of open questions, from the origin of the elements to stellar evolution. Inherent part of the conference is a school devoted to students and young scientists where prominent scientists introduce the field of nuclear astrophysics to the participants. Conference Topics: Cosmology and big bang nucleosynthesis; Element production, stellar evolution and stellar explosions; Evidences of nucleosynthesis in stars and in presolar grains; Experiments in nuclear astrophysics; Nuclei far from stability; Nuclear theory in astrophysics; New facilities. [TRA

  1. Photoabsorption in nuclei

    OpenAIRE

    Effenberger, M.; Mosel, U.

    1997-01-01

    We calculate the total photoabsorption cross section and cross sections for inclusive pion and eta photoproduction in nuclei in the energy range from 300 MeV to 1 GeV within the framework of a semi-classical BUU transport model. Besides medium modifications like Fermi motion and Pauli blocking we focus on the collision broadening of the involved resonances. The resonance contributions to the elementary cross section are fixed by fits to partial wave amplitudes of pion photoproduction. The cro...

  2. Gluon density in nuclei

    OpenAIRE

    Ayala, A. L.; Ducati, M. B. Gay; Levin, E. M.

    1996-01-01

    In this talk we present our detail study ( theory and numbers) [1] on the shadowing corrections to the gluon structure functions for nuclei. Starting from rather contraversial information on the nucleon structure function which is originated by the recent HERA data, we develop the Glauber approach for the gluon density in a nucleus based on Mueller formula [2] and estimate the value of the shadowing corrections in this case. Than we calculate the first corrections to the Glauber approach and ...

  3. Structures of exotic nuclei

    International Nuclear Information System (INIS)

    Discoveries of many different types of nuclear shape coexistence are being found at both low and high excitation energies throughout the periodic table, as documented in recent reviews. Many new types of shape coexistence have been observed at low excitation energies, for examples bands on more than four different overlapping and coexisting shapes are observed in 185Au, and competing triaxial and prolate shapes in 71Se and 176Pt. Discrete states in super-deformed bands with deformations β 2 ∼ 0.4-0.6, coexisting with other shapes, have been seen to high spin up to 60ℎ in 152Dy, 132Ce and 135Nd. Super-deformed nuclei with N and Z both around 38 and around Z = 38, N ≥ 60. These data led to the discovery of new shell gaps and magic numbers of 38 for N and Z and 60 for N but now for deformed shapes. Marked differences in structure are observed at spins of 6 to 20 in nuclei in this region, which differ by only two protons; for example, 68Ge and 70Se. The differences are thought to be related to the competing shell gaps in these nuclei

  4. On Quasibound N* Nuclei

    CERN Document Server

    Kelkar, N G; Moskal, P

    2015-01-01

    The possibility for the existence of unstable bound states of the S11 nucleon resonance N$^*$(1535) and nuclei is investigated. These quasibound states are speculated to be closely related to the existence of the quasibound states of the eta mesons and nuclei. Within a simple model for the N N$^*$ interaction involving a pion and eta meson exchange, N$^*$-nucleus potentials for N*-$^3$He and N*-$^{24}$Mg are evaluated and found to be of a Woods-Saxon like form which supports two to three bound states. In case of N*-$^3$He, one state bound by only a few keV and another by 4 MeV is found. The results are however quite sensitive to the N N$^*$ $\\pi$ and N N$^*$ $\\eta$ vertex parameters. A rough estimate of the width of these states, based on the mean free path of the exchanged mesons in the nuclei leads to very broad states with $\\Gamma \\sim$ 80 and 110 MeV for N*-$^3$He and N*-$^{24}$Mg respectively.

  5. Enumeration of islets by nuclei counting and light microscopic analysis

    OpenAIRE

    Pisania, Anna; Papas, Klearchos K.; Powers, Daryl E.; Rappel, Michael J.; Omer, Abdulkadir; Bonner-Weir, Susan; Weir, Gordon C.; Colton, Clark K.

    2010-01-01

    Islet enumeration in impure preparations by conventional dithizone staining and visual counting is inaccurate and operator dependent. We examined nuclei counting for measuring the total number of cells in islet preparations, and we combined it with morphological analysis by light microscopy (LM) for estimating the volume fraction of islets in impure preparations. Cells and islets were disrupted with lysis solution and shear, and accuracy of counting successively diluted nuclei suspensions was...

  6. The role of nuclei, polyribosomes and cytosol factors in the onset of the acute-phase reaction in the liver cell.

    OpenAIRE

    Piccoletti, R.; Aletti, M. G.; Cajone, F.; Bernelli-Zazzera, A.

    1984-01-01

    Nuclei isolated from livers of turpentine-treated rats show an increased RNA synthesis, reaching a maximum at 10 h after treatment. The stimulation affects both alpha-amanitin-resistant and alpha-amanitin-sensitive activities, suggesting that pre-ribosomal and pre-messenger RNA formation are activated at the same time and to the same extent. The amount of ribosomal RNA, which is still normal 10 h after treatment, increases significantly at 24 h, but the increase is limited to the bound riboso...

  7. Dynamic Chirality in Nuclei

    International Nuclear Information System (INIS)

    Chirality has recently been proposed as a novel feature of rotating nuclei [1]. Because the chiral symmetry is dichotomic, its spontaneous breaking by the axial angular momentum vector leads to doublets of closely lying rotational bands of the same parity. To investigate nuclear chirality, next to establish the existence of almost degenerate rotational bands, it is necessary to measure also other observables and compare them to the model predictions. The crucial test for the suggested nuclei as candidates to express chirality is based on precise lifetime measurements. Two lifetime experiments and theoretical approaches for the description of the experimental results will be presented. Lifetimes of exited states in 134Pr were measured [2,3] by means of the recoil distance Doppler-shift and Doppler-shift attenuation techniques. The branching ratios and the electric or magnetic character of the transitions were also investigated [3]. The experiments were performed at IReS, Strasbourg, using the EUROBALL IV spectrometer, in conjunction with the inner bismuth germanate ball and the Cologne coincidence plunger apparatus. Exited states in 134Pr were populated in the fusion-evaporation reaction 119Sn(19F, 4n)134Pr. The possible chiral interpretation of twin bands was investigated in the two-quasiparticle triaxial rotor [1] and interacting boson-fermion-fermion models [4]. Both theoretical approaches can describe the level-scheme of 134Pr. The analysis of the wave functions has shown that the possibility for the angular momenta of the proton, neutron, and core to find themselves in the favorable, almost orthogonal geometry, is present but is far from being dominant [3,5]. The structure is characterized by large β and γ fluctuations. The existence of doublets of bands in 134Pr can be attributed to weak chirality dominated by shape fluctuations. In a second experiment branching ratios and lifetimes in 136Pm were measured by means of the recoil distance Doppler-shift and

  8. Active galactic nuclei

    CERN Document Server

    Beckmann, Volker

    2012-01-01

    This AGN textbook includes phenomena based on new results in the X-Ray domain from new telescopes such as Chandra and XMM Newton not mentioned in any other book. Furthermore, it considers also the Fermi Gamma Ray Space Telescope with its revolutionary advances of unprecedented sensitivity, field of view and all-sky monitoring. Those and other new developments as well as simulations of AGN merging events and formations, enabled through latest super-computing capabilities. The book gives an overview on the current knowledge of the Active Galacitc Nuclei phenomenon. The spectral energy d

  9. Active galactic nuclei

    CERN Document Server

    Blandford, RD; Woltjer, L

    1990-01-01

    Starting with this volume, the Lecture Notes of the renowned Advanced Courses of the Swiss Society for Astrophysics and Astronomy will be published annually. In each course, three extensive lectures given by leading experts in their respective fields cover different and essential aspects of the subject. The 20th course, held at Les Diablerets in April 1990, dealt with current research on active galactic nuclei; it represents the most up-to-date views on the subject, presented with particular regard for clarity. The previous courses considered a wide variety of subjects, beginning with ""Theory

  10. Particles and nuclei, letters

    International Nuclear Information System (INIS)

    The present collection of letters from JINR, Dubna, contains eight separate records on the interaction of high energy Λ6He hypernuclear beams with atomic nuclei, the position-sensitive detector of a high spatial resolution on the basis of a multiwire gas electron multiplier, pseudorapidity hadron density at the LHC energy, high precision laser control of the ATLAS tile-calorimeter module mass production at JINR, a new approach to ECG's features recognition involving neural network, subcriticity of a uranium target enriched in 235U, beam space charge effects in high-current cyclotron injector CI-5, a homogeneous static gravitational field and the principle of equivalence

  11. Particles and nuclei, letters

    International Nuclear Information System (INIS)

    The present collection of letters from JINR, Dubna, contains six separate records on the DELPHI experiment at LEP, the Fermi-surface dynamics of rotating nuclei, production of large samples of the silica dioxide aerogel in the 37-litre autoclave and test of its optical properties, preliminary radiation resource results on scintillating fibers, a new algorithm for the direct transformation method of time to digital with the high time resolution and development and design of analogue read-out electronics for HADES drift chamber system

  12. Photoabsorption on nuclei

    OpenAIRE

    Effenberger, M.; Hombach, A; Teis, S.; Mosel, U.

    1996-01-01

    We calculate the total photoabsorption cross section on nuclei in the energy range from 300 MeV to 1 GeV within the framework of a semi-classical phase space model. Besides medium modifications like Fermi motion and Pauli blocking we focus on the collision broadening of the involved resonances. The resonance contributions to the elementary cross section are fixed by fits to partial wave amplitudes of pion photoproduction. The cross sections for $N \\, R \\to N \\, N$, needed for the calculation ...

  13. Low-Luminosity Seyfert Nuclei

    CERN Document Server

    Ho, L C; Sargent, W L W; Ho, Luis C.; Filippenko, Alexei V.; Sargent, Wallace L. W.

    1996-01-01

    We describe a new sample of Seyfert nuclei discovered during the course of an optical spectroscopic survey of nearby galaxies. The majority of the objects, many recognized for the first time, have luminosities much lower than those of classical Seyferts and populate the faint end of the AGN luminosity function. A significant fraction of the nuclei emit broad H-alpha emission qualitatively similar to the broad lines seen in classical Seyfert 1 nuclei and QSOs.

  14. Electron scattering for exotic nuclei

    Indian Academy of Sciences (India)

    Toshimi Suda

    2014-11-01

    A brand-new electron scattering facility, the SCRIT Electron Scattering Facility, will soon start its operation at RIKEN RI Beam Factory, Japan. This is the world’s first electron scattering facility dedicated to the structure studies of short-lived nuclei. The goal of this facility is to determine the charge density distributions of short-lived exotic nuclei by elastic electron scattering. The first collision between electrons and exotic nuclei will be observed in the year 2014.

  15. Calciumreleasing activity induced by nuclei of mouse fertilized early embryos

    Institute of Scientific and Technical Information of China (English)

    2003-01-01

    At fertilization, repetitive transient rises of intracellular calcium concentration occur in all mammals studied so far. It has been shown that calcium rises could be induced when mouse fertilized 1-, 2-cell nuclei were transplanted into unfertilized eggs and that the reconstituted embryo could be activated. However, whether the capability of inducing calcium rises occurs in all stages of mammalian embryos remains unknown. In this study, by using the nuclear transplantation technique and measurement of intracellular calcium rises in living cells, we showed that only the nuclei from mouse fertilized 1-cell and 2-cell embryos, neither the nuclei from 4-, 8-cell and ethanol activated parthenogenetic embryos nor 2 or 3 nuclei of electrofused 4-cell stage syncytium, have calcium-releasing activity when they were transferred into unfertilized mature oocytes. Our results indicate that the calcium-releasing activity in nuclei of 1-, 2-cell embryos is produced during fertilization and exists at the special stage of fertilized early embryos. These suggested that the capacity of inducing calcium release activity in fertilized early embryos is important for normal embryonic development.

  16. Particles and nuclei, letters

    International Nuclear Information System (INIS)

    The present collection of letters from JINR, Dubna, contains ten separate records on the properties of the N=82 even-even nuclei, an investigation of the charge collection for strongly irradiated silicon strip detectors of the CMS ECAL preshower, the rate capability of the CSC cathode readout electronics, the timing resolution of cathode strip chambers of the CMS ME1/1 muon station and bunch crossing identification, strengthening and damping of synchrotron oscillations, photoradiation hardness of organic scintillators, as well as on a method of anode wire incident angle calculation of the first muon station (ME1/1) of the Compact Muon Solenoid set-up (CMS), heavy ion studies with CMS HF calorimeter, an investigation of the possibility of developing iodine-containing treatment and prophylactic pharmaceuticals based on blue-green algae Spirulina platensis using neutron activation analysis, a comparison between schemes for heavy ion injection into Nuclotron booster

  17. Particles and nuclei, letters

    International Nuclear Information System (INIS)

    The present collection of letters from JINR, Dubna, contains nine separate records on the transport of the evanescent electron beam in the vacuum section with plasma disks, determination of ΔΓs from analysis of untagged decays Bs0→J/ψφ by using the method of angular moments, investigation of light nucleus clustering in relativistic multifragmentation processes, secondary fragments of relativistic 22Ne at 4.1 A · GeV/c nuclei in nuclear emulsion, extrapolation of experimental data of accelerated radiation aging to the operation condition of dipole magnet electrical insulation at low dose rates, automatic quality control system of the installed straws into TRT wheels, a new method of fast simulation for a hadron calorimeter response, empirical evidence for relation between threshold effects and neutron strength function as well as on what information can be derived when no events are registered

  18. Particles and nuclei, letters

    International Nuclear Information System (INIS)

    The present collection of letters from JINR, Dubna, contains seven separate records on the integral representation for structure functions and target mass effects, multiscale properties of DNA primary structure including cross-scale correlations, dissipative evolution of the elementary act, the fine structure of the MT=1 Gamow-Teller resonance in 147gTb→147Gd β+/EC decay, the behaviour of the TVO temperature sensors in the magnetic fields, a fast method for searching for tracks in multilayer drift chambers of HADES spectrometer, a novel approach to particle track etching including surfactant enhanced control of pore morphology, azimuthal correlations of secondary particles in 32S induced interactions with Ag(Br) nuclei at 4.5 GeV/ c/ nucleon

  19. Particles and nuclei, letters

    International Nuclear Information System (INIS)

    The present collection of letters from JINR, Dubna, contains ten separate records on Wien filter using in exploring on low-energy radioactive nuclei, memory effects in dissipative nucleus-nucleus collision, topological charge and topological susceptibility in connection with translation and gauge invariance, solutions of the multitime Dirac equation, the maximum entropy technique. System's statistical description, the charged conductor inside dielectric. Solution of boundary condition by means of auxiliary charges and the method of linear algebraic equations, optical constants of the TGS single crystal irradiated by power pulsed electron beam, interatomic pair potential and n-e amplitude from slow neutron scattering by noble gases, the two-coordinate multiwire proportional chamber of the high spatial resolution and neutron drip line in the region of O-Mg isotopes

  20. Pulsars: gigantic nuclei

    International Nuclear Information System (INIS)

    What is the real nature of pulsars? This is essentially a question of the fundamental strong interaction between quarks at low-energy scale and hence of the non-perturbative quantum chromo-dynamics, the solution of which would certainly be meaningful for us to understand one of the seven millennium prize problems (i.e., "Yang-Mills Theory") named by the Clay Mathematical Institute. After a historical note, it is argued here that a pulsar is very similar to an extremely big nucleus, but is a little bit different from the gigantic nucleus speculated 80 years ago by L. Landau. The paper demonstrates the similarity between pulsars and gigantic nuclei from both points of view: the different manifestations of compact stars and the general behavior of the strong interaction. (author)

  1. Skyrmions in nuclei

    International Nuclear Information System (INIS)

    The applications of skyrmions to the derivation of the nucleon-nucleon force are now over a dozen years old, and this occasion is used to assess the degree of success of the endeavor. A very brief review is given of the use of skyrmions for determining single-baryon properties. Then their use for two-nucleon systems is described, with attention to the use of the product ansatz, the full structure of the lagrangian, baryon resonance admixtures, dilatons, and exact solutions for the B=2 system in order to find the sources of attraction in the central potential. We briefly address possible insights into the behavior of the nucleon in nuclei achieved from the skyrmion approach. (author)

  2. Exotic nuclei in supernovae

    International Nuclear Information System (INIS)

    In this talk I discuss properties of hot stellar matter at sub-nuclear densities which is formed in supernova explosions. I emphasize that thermodynamic conditions in this case are rather similar to those created in the laboratory by intermediate-energy heavy-ion collisions. Theoretical methods developed for the interpretation of multi-fragment final states in such reactions can be used also for description of the stellar matter. I present main steps of the statistical approach to the equation of state and nuclear composition, dealing with an ensemble of nuclear species instead of one “average” nucleus. Finally some results of this approach are presented. The emphasis is put on possible formation of heavy and superheavy nuclei. (author)

  3. Electron scattering off nuclei

    International Nuclear Information System (INIS)

    Two recently developed aspects related to the scattering of electrons off nuclei are presented. On the one hand, a model is introduced which emphasizes the relativistic aspects of the problem in the impulse approximation, by demanding strict maintenance of the algebra of the Poincare group. On the other hand, the second model aims at a more sophisticated description of the nuclear response in the case of collective excitations. Basically, it utilizes the RPA formalism with a new development which enables a more careful treatment of the states in the continuum as is the case for the giant resonances. Applications of both models to the description of elastic scattering, inelastic scattering to discrete levels, giant resonances and the quasi-elastic region are discussed. (Author)

  4. Gluon density in nuclei

    CERN Document Server

    Ayala, A P; Levin, E M

    1996-01-01

    In this talk we present our detail study ( theory and numbers) [1] on the shadowing corrections to the gluon structure functions for nuclei. Starting from rather contraversial information on the nucleon structure function which is originated by the recent HERA data, we develop the Glauber approach for the gluon density in a nucleus based on Mueller formula [2] and estimate the value of the shadowing corrections in this case. Than we calculate the first corrections to the Glauber approach and show that these corrections are big. Based on this practical observation we suggest the new evolution equation which takes into account the shadowing corrections and solve it. We hope to convince you that the new evolution equation gives a good theoretical tool to treat the shadowing corrections for the gluons density in a nucleus and, therefore, it is able to provide the theoretically reliable initial conditions for the time evolution of the nucleus - nucleus cascade.

  5. Clusters in nuclei

    CERN Document Server

    Beck, Christian

    Following the pioneering discovery of alpha clustering and of molecular resonances, the field of nuclear clustering is today one of those domains of heavy-ion nuclear physics that faces the greatest challenges, yet also contains the greatest opportunities. After many summer schools and workshops, in particular over the last decade, the community of nuclear molecular physicists has decided to collaborate in producing a comprehensive collection of lectures and tutorial reviews covering the field. This third volume follows the successful Lect. Notes Phys. 818 (Vol. 1) and 848 (Vol. 2), and comprises six extensive lectures covering the following topics:  - Gamma Rays and Molecular Structure - Faddeev Equation Approach for Three Cluster Nuclear Reactions - Tomography of the Cluster Structure of Light Nuclei Via Relativistic Dissociation - Clustering Effects Within the Dinuclear Model : From Light to Hyper-heavy Molecules in Dynamical Mean-field Approach - Clusterization in Ternary Fission - Clusters in Light N...

  6. Collective excitations in nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Chomaz, Ph. [Grand Accelerateur National d`Ions Lourds (GANIL), 14 - Caen (France); Collaboration: La Direction des Sciences de la Matiere du CEA (FR); Le Fonds National de la Recherche Scientifique de Belgique (BE)

    1998-12-31

    The properties of the nucleus cannot be reduced to the properties of its constituents: it is a complex system. The fact that many properties of the nucleus are consequences of the existence of mean-field potential is a manifestation of this complexity. In particular, the nucleons can thus self-organize in collective motions such as giant resonances. Therefore the study of this collective motions is a very good tool to understand the properties of the nucleus itself. The purpose of this article is to stress some aspects of these collective vibrations. We have studied how an ensemble of fermions as the nucleus can self-organize in collective vibrations which are behaving like a gas of bosons in weak interaction. Understanding of these phenomena remains one of the important subjects of actuality in the context of quantal systems in strong interaction. In particular, the study of the states with one or two vibration quanta provides a direct information on the structure of nuclei close to their ground states. Moreover, some collective states appear to be very robust against the onset of chaos. This is the case of the hot giant dipole built on top of a hot nucleus which seems to survive up to rather high temperatures. Their sudden disappearance is still a subject of controversy. It may be that the mean-field and the associated collective states are playing a crucial role also in catastrophic processes such as the phase-transitions. Indeed, when the system is diluted the collective vibrations may become unstable and it seems that these unstable modes provide a natural explanation to the self organization of the system in drops. Finally, considering the diversity of the different structures of exotic nuclei one may expect new vibration types. All these studies are showing the diversity of the collective motions of strongly correlated quantum systems such as the nucleus but many open questions remain to be solved. (authors) 304 refs., 53 figs., 5 tabs.

  7. Collective excitations in nuclei

    International Nuclear Information System (INIS)

    The properties of the nucleus cannot be reduced to the properties of its constituents: it is a complex system. The fact that many properties of the nucleus are consequences of the existence of mean-field potential is a manifestation of this complexity. In particular, the nucleons can thus self-organize in collective motions such as giant resonances. Therefore the study of this collective motions is a very good tool to understand the properties of the nucleus itself. The purpose of this article is to stress some aspects of these collective vibrations. We have studied how an ensemble of fermions as the nucleus can self-organize in collective vibrations which are behaving like a gas of bosons in weak interaction. Understanding of these phenomena remains one of the important subjects of actuality in the context of quantal systems in strong interaction. In particular, the study of the states with one or two vibration quanta provides a direct information on the structure of nuclei close to their ground states. Moreover, some collective states appear to be very robust against the onset of chaos. This is the case of the hot giant dipole built on top of a hot nucleus which seems to survive up to rather high temperatures. Their sudden disappearance is still a subject of controversy. It may be that the mean-field and the associated collective states are playing a crucial role also in catastrophic processes such as the phase-transitions. Indeed, when the system is diluted the collective vibrations may become unstable and it seems that these unstable modes provide a natural explanation to the self organization of the system in drops. Finally, considering the diversity of the different structures of exotic nuclei one may expect new vibration types. All these studies are showing the diversity of the collective motions of strongly correlated quantum systems such as the nucleus but many open questions remain to be solved. (authors)

  8. Quarks in Few Body Nuclei

    Directory of Open Access Journals (Sweden)

    Holt Roy J.

    2016-01-01

    Full Text Available Electron scattering at very high Bjorken x from hadrons provides an excellent test of models, has an important role in high energy physics, and from nuclei, provides a window into short range correlations. Light nuclei have a key role because of the relatively well-known nuclear structure. The development of a novel tritium target for Jefferson Lab has led to renewed interest in the mass three system. For example, deep inelastic scattering experiments in the light nuclei provide a powerful means to determine the neutron structure function. The isospin dependence of electron scattering from mass-3 nuclei provide information on short range correlations in nuclei. The program using the new tritium target will be presented along with a summary of other experiments aimed at revealing the large-x structure of the nucleon.

  9. Quarks in Few Body Nuclei

    Science.gov (United States)

    Holt, Roy J.

    2016-03-01

    Electron scattering at very high Bjorken x from hadrons provides an excellent test of models, has an important role in high energy physics, and from nuclei, provides a window into short range correlations. Light nuclei have a key role because of the relatively well-known nuclear structure. The development of a novel tritium target for Jefferson Lab has led to renewed interest in the mass three system. For example, deep inelastic scattering experiments in the light nuclei provide a powerful means to determine the neutron structure function. The isospin dependence of electron scattering from mass-3 nuclei provide information on short range correlations in nuclei. The program using the new tritium target will be presented along with a summary of other experiments aimed at revealing the large-x structure of the nucleon.

  10. Quantitative Morphometic Analysis of Cell Nuclei and Change of ER and PR Expression in Breast Carcinoma%乳腺癌ER、PR抗原表达与细胞核形态定量变化

    Institute of Scientific and Technical Information of China (English)

    苗小芬; 王睿; 曹幼甫

    2011-01-01

    目的 研究乳腺癌雌激素受体(ER)、孕激素受体(PR)表达与细胞核变化的关系,探讨其临床应用价值.方法 选择苏州市中医院病理科2002年以来42例乳腺癌标本,总结其ER和PR表达,并作细胞核形态定量图像分析;同时与20例良性病变对比.结果 乳腺癌细胞核等圆直径、面积及边缘周长,均较良性对照组为大,差别有统计学意义(P<0.01).ER+/PR-病例细胞核形态定量与ER+/PR+比较,差别有统计学意义(P<0.05);ER-PR-病例细胞核形态定量与ER+/PR+比较,差别有统计学意义(P<0.01).乳腺癌ER和PR可同时或分别失表达,PR失表达病例细胞核形态变量较大,尤其ER和PR同时失表达病例细胞核形态变量更大.结论 良、恶性乳腺病变细胞核形态定量差别显著,对鉴别诊断有实用价值.ER和PR的表达结合细胞核形态学测量结果对治疗和预后的评估有意义.%Objective To study the expression of hormone receptor and the nuclei morphometry in breast cancer. Methods Several morphometric parameters of cell nuclei were detected by means of a quantitative pathologic technique on 42 cases of breast cancer and 20 cases of benign lesions of the breast respectively. Immunohistochemical SP method was used to detect expression of estrogen receptor(ER) and progesterone receptor(PR) in breast cancer. Results The diameter of nuclei, the area of nuclei and the circumference in cases of breast cancer was found to be significantly larger than those in benign breast lesions( P <0. 01 ). Nuclei morphometry in cases of ER +/PR + was significantly different from that in cases of ER +/PR-( P < 0.05 ) and ER -/PR- (P <0.01 ) in breast cancer respectively. The morphometric data in ER +/PR - cases of breast cancer were larger than those in ER -/PR + eases of breast cancer, and largest values were observed in ER -/PR - cases of breast cancer. Conclusion It was of application for morphometry analysis to distinguish benign breast

  11. Monopole transitions in hot nuclei

    International Nuclear Information System (INIS)

    Monopole transitions can be a signature of shape changing in a hot, pulsating nucleus (the low energy E0 mode) and/or a measure of the compressibility of finite nuclei (GMR, the breathing mode). Experimental information pertaining to GMR is reviewed. Recipes for deducing the incompressibility modules for infinite nuclear matter from data on GMR are discussed. Astrophysical implications are outlined. The first attempts at locating the GMR strength in moderately hot nuclei are described. Prospects for improving the experimental techniques to make an observation of this strength in selected nuclei unambiguous are discussed. (author). 46 refs, 8 figs

  12. Spectroscopy of heavy fissionable nuclei

    Indian Academy of Sciences (India)

    S K Tandel

    2015-09-01

    Structural studies of heavy nuclei are quite challenging due to increased competition from fission, particularly at high spins. Nuclei in the actinide region exhibit a variety of interesting phenomena. Recent advances in instrumentation and analysis techniques have made feasible sensitive measurements of nuclei populated with quite low cross-sections. These include isomers and rotational band structures in isotopes of Pu ( = 94) to Rf ( = 104), and octupole correlations in the Th ( = 90) region. The obtained experimental data have provided insights on various aspects like moments of inertia and nucleon alignments at high spins, quasiparticle energies and evolution of quadrupole and octupole collectivity, among others. An overview of some of these results is presented.

  13. Particles and nuclei, letters

    International Nuclear Information System (INIS)

    The present collection of letters from JINR, Dubna, contains ten separate records on the role of the Coulomb distortion in form-factor calculations for 12C with alpha-clusterization and nucleon-nucleon correlations, optimization of a set-up for the investigation of the light-nuclei spin structure at the internal target of the Nuclotron, precessing deuteron polarization, connection of the parameter estimation quality of maximum likelihood and generalized moments, determination of the total energy QEC for 156Ho(T1/2∼56 min)β+/EC decay using the total absorption γ-ray spectrometer, selection of signal events in the DUBTO experiment, a search for the dineutron in the interaction of neutrons with deuterons, tracking performance of the HERA-B outer tracker PC chambers, construction and manufacture of large size straw-chambers of the COMPASS spectrometer tracking system, as well as on the charge form factor and the nucleon momentum distribution of 24He and their centre-of-mass correction

  14. Collective excitations in nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Chomaz, Ph

    1997-12-31

    The properties of the nucleus cannot be reduced to the properties of its constituents: it is a complex system. The fact that many properties of the nucleus are consequences of the existence of mean-field potential is a manifestation of this complexity. In particular the nucleons can thus self-organize in collective motions such as giant resonances. Therefore the study of these collective motions is a very good to understand the properties of the nucleus itself. The purpose of this article was to stress some aspects of these collective vibrations. In particular we have studied how an ensemble of fermions as the nucleus can self-organize in collective vibrations which are behaving like a gas of bosons in weak interaction. The understanding of these phenomena remains one of the important subjects of actually in the context of quantal systems in strong interaction. In particular the study of the states with one or two vibration quanta provides a direct information on the structure if nuclei close to their ground states. (author) 270 refs.

  15. Collective excitations in nuclei

    International Nuclear Information System (INIS)

    The properties of the nucleus cannot be reduced to the properties of its constituents: it is a complex system. The fact that many properties of the nucleus are consequences of the existence of mean-field potential is a manifestation of this complexity. In particular the nucleons can thus self-organize in collective motions such as giant resonances. Therefore the study of these collective motions is a very good to understand the properties of the nucleus itself. The purpose of this article was to stress some aspects of these collective vibrations. In particular we have studied how an ensemble of fermions as the nucleus can self-organize in collective vibrations which are behaving like a gas of bosons in weak interaction. The understanding of these phenomena remains one of the important subjects of actually in the context of quantal systems in strong interaction. In particular the study of the states with one or two vibration quanta provides a direct information on the structure if nuclei close to their ground states. (author)

  16. Antibaryons bound in nuclei

    CERN Document Server

    Mishustin, I N; Buervenich, T J; Stöcker, H; Greiner, W

    2005-01-01

    We study the possibility of producing a new kind of nuclear systems which in addition to ordinary nucleons contain a few antibaryons (antiproton, antilambda, etc.). The properties of such systems are described within the relativistic mean-field model by employing G-parity transformed interactions for antibaryons. Calculations are first done for infinite systems and then for finite nuclei from He to Pb. It is demonstrated that the presence of a real antibaryon leads to a strong rearrangement of a target nucleus resulting in a significant increase of its binding energy and local compression. Noticeable effects remain even after the antibaryon coupling constants are reduced by factor 3-4 compared to G-parity motivated values. We have performed detailed calculations of the antibaryon annihilation rates in the nuclear environment by applying a kinetic approach. It is shown that due to significant reduction of the reaction Q-values, the in-medium annihilation rates should be strongly suppressed leading to relativel...

  17. Gluon density in nuclei

    International Nuclear Information System (INIS)

    In this talk we present our detailed study (theory and numbers) on the shadowing corrections to the gluon structure functions for nuclei. Starting from rather controversial information on the nucleon structure function which is originated by the recent HERA data, we develop the Glauber approach for the gluon density in a nucleus based on Mueller formula and estimate the value of the shadowing corrections in this case. Then we calculate the first corrections to the Glauber approach and show that these corrections are big. Based on this practical observation we suggest the new evolution equation which takes into account the shadowing corrections and solve it. We hope to convince you that the new evolution equation gives a good theoretical tool to treat the shadowing corrections for the gluons density in a nucleus and, therefore, it is able to provide the theoretically reliable initial conditions for the time evolution of the nucleus-nucleus cascade. The initial conditions should be fixed both theoretically and phenomenologically before to attack such complicated problems as the mixture of hard and soft processes in nucleus-nucleus interactions at high energy or the theoretically reliable approach to hadron or/and parton cascades for high energy nucleus-nucleus interaction. 35 refs., 24 figs., 1 tab

  18. Gluon density in nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Ayala, A.L. [Rio Grande do Sul Univ., Porto Alegre, RS (Brazil). Inst. de Fisica][Pelotas Univ., RS (Brazil). Inst. de Fisica e Matematica; Ducati, M.B.G. [Rio Grande do Sul Univ., Porto Alegre, RS (Brazil). Inst. de Fisica; Levin, E.M. [Fermi National Accelerator Lab., Batavia, IL (United States)][Nuclear Physics Inst., St. Petersburg (Russian Federation)

    1996-10-01

    In this talk we present our detailed study (theory and numbers) on the shadowing corrections to the gluon structure functions for nuclei. Starting from rather controversial information on the nucleon structure function which is originated by the recent HERA data, we develop the Glauber approach for the gluon density in a nucleus based on Mueller formula and estimate the value of the shadowing corrections in this case. Then we calculate the first corrections to the Glauber approach and show that these corrections are big. Based on this practical observation we suggest the new evolution equation which takes into account the shadowing corrections and solve it. We hope to convince you that the new evolution equation gives a good theoretical tool to treat the shadowing corrections for the gluons density in a nucleus and, therefore, it is able to provide the theoretically reliable initial conditions for the time evolution of the nucleus-nucleus cascade. The initial conditions should be fixed both theoretically and phenomenologically before to attack such complicated problems as the mixture of hard and soft processes in nucleus-nucleus interactions at high energy or the theoretically reliable approach to hadron or/and parton cascades for high energy nucleus-nucleus interaction. 35 refs., 24 figs., 1 tab.

  19. Radiation-induced DNA double-strand breaks produced in histone-depleted tumor cell nuclei measured using the neutral comet assay

    International Nuclear Information System (INIS)

    Removal of histones and other nuclear proteins greatly enhances the sensitivity of mammalian cells to DNA damage by ionizing radiation. We examined the possibility that the ease of dissociation of histones, or the association of other nuclear proteins with DNA, may differ between radioresistant and sensitive human tumor cells. Cells embedded in agarose were exposed to increasing salt concentrations prior to irradiation and examination using a microscopic gel electrophoresis method, the neutral comet assay. Induction of double-strand breaks increased by a factor of about 20 when cells of four human tumor cell line HT144 melanoma, HT29 adenocarcinoma, DU145 prostate carcinoma and U87 glioma, were exposed to 2 M NaCl; however, no correlation with radiosensitivity was apparent. While a significant number of histone and non-histone proteins are present after extraction with 1.2 M NaCL, these proteins apparently have only a minor influence on radiosensitivity. However, if they are allowed to remain with DNA during electrophoresis, about 15 times more strand breaks are required to produce a similar amount of DNA migration in both DU145 and HT144 cells. These results suggest that the association between proteins and DNA within the nucleus, as probed by extraction with sodium chloride, does not help to explain differences in intrinsic radiosensitivity among cells of these diverse tumor cell lines. 33 refs., 11 figs

  20. Physics with loosely bound nuclei

    Indian Academy of Sciences (India)

    Chhanda Samanta

    2001-08-01

    The essential aspect of contemporary physics is to understand properties of nucleonic matter that constitutes the world around us. Over the years research in nuclear physics has provided strong guidance in understanding the basic principles of nuclear interactions. But, the scenario of nuclear physics changed drastically as the new generation of accelerators started providing more and more rare isotopes, which are away from the line of stability. These weakly bound nuclei are found to exhibit new forms of nuclear matter and unprecedented exotic behaviour. The low breakup thresholds of these rare nuclei are posing new challenges to both theory and experiments. Fortunately, nature has provided a few loosely bound stable nuclei that have been studied thoroughly for decades. Attempts are being made to find a consistent picture for the unstable nuclei starting from their stable counterparts. Some significant differences in the structure and reaction mechanisms are found.

  1. Collisions between complex atomic nuclei

    International Nuclear Information System (INIS)

    The use of heavy ion accelerators in the study of nuclear structure and states is reviewed. The reactions discussed are the quasielastic reactions in which small amounts of energy and few particles are exchanged between the colliding nuclei. The development of heavy ion accelerators is also discussed, as well as detection equipment. Exotic phenomena, principally the possible existence of superheavy nuclei, are also treated. (JIW)

  2. Particles and nuclei in PANIC

    International Nuclear Information System (INIS)

    PANIC is the triennal International Conference on Particles and Nuclei, and judging from the latest PANIC, held in Kyoto from 20-24 April there is no need for panic yet. Faced with two pictures – one of nuclei described in nucleon and meson terms, and another of nucleons containing quarks and gluons – physicists are intrigued to know what new insights from the quark level can tell us about nuclear physics, or vice versa

  3. Investigation of copper nuclei

    International Nuclear Information System (INIS)

    An extensive study has been performed on copper isotopes in the mass region A=63-66. The results of a precise measurement are presented on the properties of levels of 64Cu and 66Cu. They were obtained by bombarding the 63Cu and 65Cu nuclei with neutrons. The gamma spectra collected after capture of thermal, 2-keV, 24-keV neutrons have been analysed and combined to give a rather extensive set of precise level energies and gamma transition strengths. From the angular distribution of the gamma rays it is possible to obtain information concerning the angular momentum J of several low-lying states. The level schemes derived from such measurements have been used as a test for calculations in the framework of the shell model. The spectral distributions of eigenstates in 64Cu for different configuration spaces are presented and discussed. In this study the relative importance of configurations with n holes in the 1f7/2 shell with n up to 16, are investigated. It is found that the results strongly depend on the values of the single-particle energies. The results of the spectral-distribution method were utilized for shell-model calculations. From the information obtained from the spectral analysis it was decided to adopt a configuration space which includes up to one hole in the 1f7/2 shell and up to two particles in the 1g9/2 shell. Further, restrictions on seniority and on the coupling of the two particles in the 1g9/2 orbit have been applied and their effects have been studied. It is found that the calculated excitation energies reproduce the measured values in a satisfactory way, but that some of the electromagnetic properties are less well in agreement with experimental data. (Auth.)

  4. A variety of kaonic nuclei

    International Nuclear Information System (INIS)

    We have investigated systematically kaonic nuclei which are ppnK-, pppK-, pppnK-, 6BeK-, 9BK- and 11CK-. Since I = 0 K-barN interaction, which is very attractive, plays an essential role in kaonic nuclei, we should treat it adequately. For this purpose, we have improved the framework of antisymmetrized molecular dynamics (AMD): 1) we can treat pK-/nK-bar0 mixing and 2) perform not only angular-momentum projection but also isospin projection. As a result of our calculation with a new framework of AMD, all kaonic nuclei we calculated are deeply bound by about 100 MeV as a discrete state. They have various structures with highly dense state. We have also investigated double kaonic nuclei, ppnK-K- and ppnK-K-. They are more shrunk than single kaonic nuclei, but the binding energy per single kaon (E(K-bar)) is about 100 MeV, which is equal to that in the case of single kaonic nuclei. (author)

  5. Individual cells in the raphe nuclei of the medulla oblongata in rat that contain immunoreactivities for both serotonin and enkephalin project to the spinal cord.

    Science.gov (United States)

    Millhorn, D E; Hökfelt, T; Verhofstad, A A; Terenius, L

    1989-01-01

    The ventral medulla oblongata of rats was analyzed with a double-labelling immunofluorescence technique using guinea pig antibodies directed against serotonin (5-HT) and rabbit antisera directed against enkephalin (ENK). Numerous cells in the region of nucleus raphe obscurus, nucleus raphe pallidus and nucleus raphe magnus showed immunostaining for either 5-HT or ENK. A substantial number of cells showed positive immunostaining for both 5-HT and ENK. 5-HT/ENK double-labelled cells were most frequently encountered in an area that extended from the rostral aspect of the inferior olivary nucleus to the pontomedullary border. This region corresponds anatomically to nucleus raphe magnus/nucleus paragigantocellularis. In addition, a number of the 5-HT/ENK-containing cells were retrogradely labelled with Fluoro-Gold dye that had been injected into the thoracic spinal cord several days prior to perfusion. Schematic drawings showing the anatomical distribution of 5-HT/ENK colocalization are provided. PMID:2744110

  6. Enumeration of islets by nuclei counting and light microscopic analysis.

    Science.gov (United States)

    Pisania, Anna; Papas, Klearchos K; Powers, Daryl E; Rappel, Michael J; Omer, Abdulkadir; Bonner-Weir, Susan; Weir, Gordon C; Colton, Clark K

    2010-11-01

    Islet enumeration in impure preparations by conventional dithizone staining and visual counting is inaccurate and operator dependent. We examined nuclei counting for measuring the total number of cells in islet preparations, and we combined it with morphological analysis by light microscopy (LM) for estimating the volume fraction of islets in impure preparations. Cells and islets were disrupted with lysis solution and shear, and accuracy of counting successively diluted nuclei suspensions was verified with (1) visual counting in a hemocytometer after staining with crystal violet, and automatic counting by (2) aperture electrical resistance measurement and (3) flow cytometer measurement after staining with 7-aminoactinomycin-D. DNA content averaged 6.5 and 6.9 pg of DNA per cell for rat and human islets, respectively, in agreement with literature estimates. With pure rat islet preparations, precision improved with increasing counts, and samples with about ≥160 islets provided a coefficient of variation of about 6%. Aliquots of human islet preparations were processed for LM analysis by stereological point counting. Total nuclei counts and islet volume fraction from LM analysis were combined to obtain the number of islet equivalents (IEs). Total number of IE by the standard method of dithizone staining/manual counting was overestimated by about 90% compared with LM/nuclei counting for 12 freshly isolated human islet research preparations. Nuclei counting combined with islet volume fraction measurements from LM is a novel method for achieving accurate islet enumeration. PMID:20697375

  7. From heavy nuclei to super-heavy nuclei

    International Nuclear Information System (INIS)

    The existence of super-heavy nuclei has been predicted nearly fifty years ago. Due to the strong coulomb repulsion, the stabilisation of these nuclei is possible only through shell effects. The reasons for this fragile stability, as well as the theoretical predictions concerning the position of the island of stability are presented in the first part of this lecture. In the second part, experiments and experimental techniques which have been used to synthesize or search for super-heavy elements are described. Spectroscopic studies performed in very heavy elements are presented in the following section. We close this lecture with techniques that are currently being developed in order to reach the superheavy island and to study the structure of very-heavy nuclei. (author)

  8. Cavitation inception from bubble nuclei.

    Science.gov (United States)

    Mørch, K A

    2015-10-01

    The tensile strength of ordinary water such as tap water or seawater is typically well below 1 bar. It is governed by cavitation nuclei in the water, not by the tensile strength of the water itself, which is extremely high. Different models of the nuclei have been suggested over the years, and experimental investigations of bubbles and cavitation inception have been presented. These results suggest that cavitation nuclei in equilibrium are gaseous voids in the water, stabilized by a skin which allows diffusion balance between gas inside the void and gas in solution in the surrounding liquid. The cavitation nuclei may be free gas bubbles in the bulk of water, or interfacial gaseous voids located on the surface of particles in the water, or on bounding walls. The tensile strength of these nuclei depends not only on the water quality but also on the pressure-time history of the water. A recent model and associated experiments throw new light on the effects of transient pressures on the tensile strength of water, which may be notably reduced or increased by such pressure changes. PMID:26442138

  9. Photodissociation of neutron deficient nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Sonnabend, K.; Babilon, M.; Hasper, J.; Mueller, S.; Zarza, M.; Zilges, A. [TU Darmstadt, Institut fuer Kernphysik, Darmstadt (Germany)

    2006-03-15

    The knowledge of the cross sections for photodissociation reactions like e.g. ({gamma}, n) of neutron deficient nuclei is of crucial interest for network calculations predicting the abundances of the so-called p nuclei. However, only single cross sections have been measured up to now, i.e., one has to rely nearly fully on theoretical predictions. While the cross sections of stable isotopes are accessible by experiments using real photons, the bulk of the involved reactions starts from unstable nuclei. Coulomb dissociation (CD) experiments in inverse kinematics might be a key to expand the experimental database for p-process network calculations. The approach to test the accuracy of the CD method is explained. (orig.)

  10. Photodissociation of neutron deficient nuclei

    Science.gov (United States)

    Sonnabend, K.; Babilon, M.; Hasper, J.; Müller, S.; Zarza, M.; Zilges, A.

    2006-03-01

    The knowledge of the cross sections for photodissociation reactions like e.g. (γ, n) of neutron deficient nuclei is of crucial interest for network calculations predicting the abundances of the so-called p nuclei. However, only single cross sections have been measured up to now, i.e., one has to rely nearly fully on theoretical predictions. While the cross sections of stable isotopes are accessible by experiments using real photons, the bulk of the involved reactions starts from unstable nuclei. Coulomb dissociation (CD) experiments in inverse kinematics might be a key to expand the experimental database for p-process network calculations. The approach to test the accuracy of the CD method is explained.

  11. Cavitation inception from bubble nuclei

    DEFF Research Database (Denmark)

    Mørch, Knud Aage

    2015-01-01

    experimental investigations of bubbles and cavitation inception have been presented. These results suggest that cavitation nuclei in equilibrium are gaseous voids in the water, stabilized by a skin which allows diffusion balance between gas inside the void and gas in solution in the surrounding liquid. The...... cavitation nuclei may be free gas bubbles in the bulk of water, or interfacial gaseous voids located on the surface of particles in the water, or on bounding walls. The tensile strength of these nuclei depends not only on the water quality but also on the pressure-time history of the water. A recent model...... and associated experiments throw new light on the effects of transient pressures on the tensile strength of water, which may be notably reduced or increased by such pressure changes....

  12. Theoretical models for exotic nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Sagawa, Hiroyuki [RIKEN Nishina Center, Saitama (Japan); University of Aizu, Center for Mathematics and Physics, Fukushima (Japan); Hagino, Kouichi [Tohoku University, Department of Physics, Sendai (Japan); Tohoku University, Research Center for Electron Photon Science, Sendai (Japan); National Astronomical Observatory of Japan, Tokyo (Japan)

    2015-08-15

    We review various theoretical models which have been used to study the properties of the ground state and excited states of nuclei close to and beyond the neutron and proton drip lines. The validity and limitations of these models are discussed with applications to recent experimental findings such as di-neutron correlations in Borromian nuclei, the soft dipole excitations, direct two-neutron and two-proton decays, and odd-even staggerings of reaction cross sections. The role of isoscalar spin-triplet pairing interaction is also pointed out in the low-lying energy spectra as well as the spin- and isospin-dependent decay rates for N = Z and N = Z + 2 nuclei with mass A < 60. A characteristic feature of the Coulomb energy displacement of the Borromian nucleus {sup 11}Li is discussed in connection to the energies of isobaric analogue states (IAS) of T = 5/2 multiples in the A = 11 systems. (orig.)

  13. Spontaneous fission of superheavy nuclei

    Indian Academy of Sciences (India)

    R A Gherghescu; D N Poenaru

    2015-09-01

    The macroscopic–microscopic method is extended to calculate the deformation energy and penetrability for binary nuclear configurations typical for fission processes. The deformed two-centre shell model is used to obtain single-particle energy levels for the transition region of two partially overlapped daughter and emitted fragment nuclei. The macroscopic part is obtained using the Yukawa-plus-exponential potential. The microscopic shell and pairing corrections are obtained using the Strutinsky and BCS approaches and the cranking formulae yield the inertia tensor. Finally, the WKB method is used to calculate penetrabilities and spontaneous fission half-lives. Calculations are performed for the decay of 282,292120 nuclei.

  14. International Symposium on Exotic Nuclei

    CERN Document Server

    Sobolev, Yu G; EXON-2014

    2015-01-01

    The production and the properties of nuclei in extreme conditions, such as high isospin, temperature, angular momenta, large deformations etc., have become the subject of detailed investigations in all scientific centers. The main topics discussed at the Symposium were: Synthesis and Properties of Exotic Nuclei; Superheavy Elements; Rare Processes, Nuclear Reactions, Fission and Decays; Experimental Facilities and Scientific Projects. This book provides a comprehensive overview of the newest results of the investigations in the main scientific centers such as GSI (Darmstadt, Germany), GANIL (Caen, France), RIKEN (Wako-shi, Japan), MSU (Michigan, USA), and JINR (Dubna, Russia).

  15. Coulomb displacement energies in nuclei

    International Nuclear Information System (INIS)

    In the present work the positions of the isobaric analog resonances (IAR) are calculated using the HF-TDA theory with a complete proton particle-neutron hole basis. The important feature of this approach is the fact that the HF potential and the particle-hole interaction used in the TDA are derived from the same two-body interactions. In this theroy all the higher order effects are taken into account in one consistent framework. The calculations are performed for several N > Z, closed shell nuclei. For these nuclei good agreement between the experimental and theoretical excitation energies of the IAR is obtained. (orig.)

  16. PDFs from nucleons to nuclei

    CERN Document Server

    Accardi, Alberto

    2016-01-01

    I review recent progress in the extraction of unpolarized parton distributions in the proton and in nuclei from a unified point of view that highlights how the interplay between high energy particle physics and lower energy nuclear physics can be of mutual benefit to either field. Areas of overlap range from the search for physics beyond the standard model at the LHC, to the study of the non perturbative structure of nucleons and the emergence of nuclei from quark and gluon degrees of freedom, to the interaction of colored probes in a cold nuclear medium.

  17. Nuclei, hadrons, and elementary particles

    International Nuclear Information System (INIS)

    This book is a short introduction to the physics of the nuclei, hadrons, and elementary particles for students of physics. Important facts and model imaginations on the structure, the decay, and the scattering of nuclei, the 'zoology' of the hadrons and basic facts of hadronic scattering processes, a short introduction to quantum electrodynamics and quantum chromodynamics and the most important processes of lepton and parton physics, as well as the current-current approach of weak interactions and the Glashow-Weinberg-Salam theory are presented. (orig.) With 153 figs., 10 tabs

  18. Neutron scattering on deformed nuclei

    International Nuclear Information System (INIS)

    Measurements of neutron elastic and inelastic differential cross sections around 14 MeV for 9Be, C, 181Ta, 232Th, 238U and 239Pu have been analyzed using a coupled channel (CC) formalism for deformed nuclei and phenomenological global optical model potentials (OMP). For the actinide targets these results are compared with the predictions of a semi-microscopic calculation using Jeukenne, Lejeune and Mahaux (JLM) microscopic OMP and a deformed ground state nuclear density. The overall agreement between calculations and the measurements is reasonable good even for the very light nuclei, where the quality of the fits is better than those obtained with spherical OMP

  19. Octupole shapes in heavy nuclei

    International Nuclear Information System (INIS)

    Theoretical calculations and measurements show the presence of strong octupole correlations in thecyround states and low-lying states of odd-mass and odd-odd nuclei in the RaPa region. Evidence for octupole correlations is provided by the observation of parity doublets and reductions in M1 matrix elements, decoupling parameters, and Coriolis matrix elements Involving high-j states. Enhancement of E1 transition rates has also been observed for some of the octupole deformed nuclei. The most convincing argument for octupole deformation is provided by the similarities of the reduced alpha decay rates to the two members of parity doublets

  20. DNA synthesis in the nuclei of Pinus silvestris embryos during

    OpenAIRE

    P. Brodzki

    2015-01-01

    DNA synthesis starts earliest in the apical meristem of the shoot, and latest in the cotyledons. Mitoses appear simultaneously in the apical meristem and in the hypocotyl cortex. Synthesis continues in the mother cells of vascular elements and cotyledon parenchyma when mitosis ceases. In the cotyledons DNA synthesis is rather synchronous and leads to the elimination of 2 C nuclei.

  1. DNA synthesis in the nuclei of Pinus silvestris embryos during

    Directory of Open Access Journals (Sweden)

    P. Brodzki

    2015-05-01

    Full Text Available DNA synthesis starts earliest in the apical meristem of the shoot, and latest in the cotyledons. Mitoses appear simultaneously in the apical meristem and in the hypocotyl cortex. Synthesis continues in the mother cells of vascular elements and cotyledon parenchyma when mitosis ceases. In the cotyledons DNA synthesis is rather synchronous and leads to the elimination of 2 C nuclei.

  2. A Delaunay Triangulation Approach For Segmenting Clumps Of Nuclei

    International Nuclear Information System (INIS)

    Cell-based fluorescence imaging assays have the potential to generate massive amount of data, which requires detailed quantitative analysis. Often, as a result of fixation, labeled nuclei overlap and create a clump of cells. However, it is important to quantify phenotypic read out on a cell-by-cell basis. In this paper, we propose a novel method for decomposing clumps of nuclei using high-level geometric constraints that are derived from low-level features of maximum curvature computed along the contour of each clump. Points of maximum curvature are used as vertices for Delaunay triangulation (DT), which provides a set of edge hypotheses for decomposing a clump of nuclei. Each hypothesis is subsequently tested against a constraint satisfaction network for a near optimum decomposition. The proposed method is compared with other traditional techniques such as the watershed method with/without markers. The experimental results show that our approach can overcome the deficiencies of the traditional methods and is very effective in separating severely touching nuclei.

  3. Colostrum factor effect on the structure and functional activity of liver nuclei of irradiated pregnant rats and their embryos

    International Nuclear Information System (INIS)

    γ-radiation causes morphological and biochemical alterations in liver cell nuclei of pregnant rats and their embryos. Preventive 4-day injection of the colostrum factor to the animals before and after irradiation with the dose 2 Gy leads to the less pronounced alteration in nuclei structure, partial depression of activity of membrane - binding enzymes as well as decrease in accumulation of lipid peroxidation products in liver cell nuclei of pregnant rats and their embryos. (author)

  4. Expression of apoptotic nuclei by ultrastructural terminal deoxyribonucleotidyl transferase mediated dUTP nick end labeling and detection of FasL, caspases and PARP protein molecules in cadmium induced acute alveolar cell injury

    International Nuclear Information System (INIS)

    Cadmium causes cellular damage but the exact mechanism of apoptosis in cadmium induced acute lung injury is not clear. We investigated the sequential expression of apoptotic nuclei and detected related molecules in tissue of cadmium-induced acute lung injury. Forty Sprague-Dawley rats were sacrificed at days 1, 3, 7 and 10 after intra-tracheal cadmium injection (2.5 mg/kg). Light microscopic, ultrastructural terminal deoxyribonucleotidyl transferase mediated dUTP nick end labeling (TUNEL), and Western blot analysis for detection of FasL, Bid, cytochrome c, caspase 3 and PARP were carried out. Apoptosis occurred at day 1, and markedly decreased at days 3, 7 and 10 (11.8, 2.8, 0.9, 0.5%, respectively) determined by light microscopy and TUNEL assay. Ultrastructural TUNEL revealed two patterns of nuclear morphology according to the apoptotic stage. One pattern showed chromatin fragmentation and apoptotic nuclear body formation. The other pattern had bleb formation in the chromatin, budding with projection out to the nuclear membranes, fragmentation, segregation of chromatin clumps and apoptotic body formation. Western blot analysis showed prominent expression of FasL at days 1 and 3. Expression of Bid, cytochrome c and caspase 3 were prominent at day 1 compared to days 3, 7 and 10. PARP cleavage was prominent at day 1. In conclusion, intra-tracheal cadmium injection showed active alveolar cell apoptosis at day 1. Ultrastructural TUNEL showed various expressions according to the apoptotic nuclear stage. These studies suggest that cadmium-induced alveolar cell apoptosis is mediated by FasL and caspase-dependent mitochondrial apoptosis pathways

  5. Gluons in nuclei and pions

    International Nuclear Information System (INIS)

    The possibility of connecting apparently different descriptions of quarks in nuclei has already been shown. The authors pursue the consequences of this 'duality' for flavour-singlet distributions. An interesting possibility is that nuclear pions may have unusual quark-gluon substructure. Indeed, pions in general could be relatively 'rich' in glue. (author)

  6. Magnetic shift of magic nuclei

    International Nuclear Information System (INIS)

    The shell effect of nuclei in strong magnetic fields associated with magnetars' is considered within the shell model. It is demonstrated that the magnetic field gives rise to a change of the phase in shell-oscillations of nuclear masses. The nuclear magic numbers of the iron region are shifted significantly towards smaller mass numbers. (author)

  7. Fission dynamics of hot nuclei

    Indian Academy of Sciences (India)

    Santanu Pal; Jhilam Sadhukhan

    2014-04-01

    Experimental evidence accumulated during the last two decades indicates that the fission of excited heavy nuclei involves a dissipative dynamical process. We shall briefly review the relevant dynamical model, namely the Langevin equations for fission. Statistical model predictions using the Kramers’ fission width will also be discussed.

  8. Low energy + scattering on = nuclei

    Indian Academy of Sciences (India)

    Swapan Das; Arun K Jain

    2003-11-01

    The data for the total cross-section of + scattering on various nuclei have been analysed in the Glauber multiple scattering theory. Energy-dependent +-nucleus optical potential is generated using the forward +-nucleon scattering amplitude and the nuclear density distribution. Along with this, the calculated total +-nucleus cross-sections using the effective +-nucleon cross-section inside the nucleus are also presented.

  9. Nuclear astrophysics of light nuclei

    DEFF Research Database (Denmark)

    Fynbo, Hans Otto Uldall

    2013-01-01

    A review of nuclear astrophysics of light nuclei using radioactive beams or techniques developed for radioactive beams is given. We discuss Big Bang nucleosynthesis, with special focus on the lithium problem, aspects of neutrino-physics, helium-burning and finally selected examples of studies...

  10. Nuclei in the Skyrme model

    International Nuclear Information System (INIS)

    The application of the Skyrme model to nuclear physics is discussed. A new approach is presented in which nuclei are identified with static soliton solutions in the appropriate topological sector. When this approach is applied to the deuteron, it yields automatically the correct spin, isospin, and parity quantum numbers. 4 refs

  11. Generalized parton distributions of nuclei

    OpenAIRE

    Guzey, V.

    2009-01-01

    We review recent theoretical results on generalized parton distributions (GPDs) of nuclei, emphasizing the following three roles of nuclear GPDs: (i) complementarity to free proton GPDs, (ii) the enhancement of traditional nuclear effects such as nuclear binding, EMC effect, nuclear shadowing, and (iii) an access to novel nuclear effects such as medium modifications of bound nucleons.

  12. Octupole correlation effects in nuclei

    International Nuclear Information System (INIS)

    Octupole correlation effects in nuclei are discussed from the point of view of many-body wavefunctions as well as mean-field methods. The light actinides, where octupole effects are largest, are considered in detail. Comparisons of theory and experiment are made for energy splittings of parity doublets; E1 transition matrix elements and one-nucleon transfer reactions

  13. Fission Dynamics of Compound Nuclei

    OpenAIRE

    Iwata, Yoritaka; Heinz, Sophia

    2012-01-01

    Collisions between $^{248}$Cm and $^{48}$Ca are systematically investigated by time-dependent density functional calculations with evaporation prescription. Depending on the incident energy and impact parameter, fusion, deep-inelastic and quasi-fission events are expected to appear. In this paper, possible fission dynamics of compound nuclei is presented.

  14. Percolation and multifragmentation of nuclei

    International Nuclear Information System (INIS)

    A method to build the 'cold' nuclei as percolation clusters is suggested. Within the framework of definite assumptions of the character of nucleon-nucleon couplings breaking resulting from the nuclear reactions as description of the multifragmentation process in the hadron-nucleus and nucleus-nucleus reactions at high energies is obtained. 19 refs.; 6 figs

  15. Chiral Electroweak Currents in Nuclei

    CERN Document Server

    Riska, D O

    2016-01-01

    The development of the chiral dynamics based description of nuclear electroweak currents is reviewed. Gerald E. (Gerry) Brown's role in basing theoretical nuclear physics on chiral Lagrangians is emphasized. Illustrative examples of the successful description of electroweak observables of light nuclei obtained from chiral effective field theory are presented.

  16. Static multipole deformations in nuclei

    International Nuclear Information System (INIS)

    The physics of static multipole deformations in nuclei is reviewed. Nuclear static moments result from the delicate balance between the vibronic Jahn-Teller interaction (particle-vibration coupling) and the residual interaction (pairing force). Examples of various permanent nuclear deformations are discussed

  17. Four-body correlations in heavy nuclei

    International Nuclear Information System (INIS)

    The origin of four-body correlations in heavy nuclei is studied. It is found that the physical picture for this phenomenon can be different in heavy and light nuclei. An application to the /sup 208/Pb region is made

  18. PNA-COMBO-FISH: From combinatorial probe design in silico to vitality compatible, specific labelling of gene targets in cell nuclei.

    Science.gov (United States)

    Müller, Patrick; Rößler, Jens; Schwarz-Finsterle, Jutta; Schmitt, Eberhard; Hausmann, Michael

    2016-07-01

    Recently, advantages concerning targeting specificity of PCR constructed oligonucleotide FISH probes in contrast to established FISH probes, e.g. BAC clones, have been demonstrated. These techniques, however, are still using labelling protocols with DNA denaturing steps applying harsh heat treatment with or without further denaturing chemical agents. COMBO-FISH (COMBinatorial Oligonucleotide FISH) allows the design of specific oligonucleotide probe combinations in silico. Thus, being independent from primer libraries or PCR laboratory conditions, the probe sequences extracted by computer sequence data base search can also be synthesized as single stranded PNA-probes (Peptide Nucleic Acid probes). Gene targets can be specifically labelled with at least about 20 PNA-probes obtaining visibly background free specimens. By using appropriately designed triplex forming oligonucleotides, the denaturing procedures can completely be omitted. These results reveal a significant step towards oligonucleotide-FISH maintaining the 3d-nanostructure and even the viability of the cell target. The method is demonstrated with the detection of Her2/neu and GRB7 genes, which are indicators in breast cancer diagnosis and therapy. PMID:27237093

  19. Cluster Structure of Atomic Nuclei and Nucleosynthesis

    International Nuclear Information System (INIS)

    It is shown that the static and dynamic α-cluster models of nuclei, which describe an elastic electron scattering, photodisintegration reactions and pion double charge exchange reactions on α-cluster nuclei are in favor of the α-capture and α process of the formation of these nuclei

  20. Transmutations of atomic nuclei in hadron-nuclei nuclear collisions at GeV energies

    International Nuclear Information System (INIS)

    In hadron-nuclei nuclear collisions nuclei change their mass numbers A and the charge numbers Z. The mechanism of transmutation of a target nucleus was prompted experimentally and is described in this work. The information about the nuclei transmutation may be a basis for elaboration of the method of nuclei changes in beams of hadrons from accelerators

  1. A Marker Controlled Watershed Algorithm with Priori Shape Information for Segmentation of Clustered Nuclei

    Directory of Open Access Journals (Sweden)

    M. Mohideen Fatima Alias Niraimathi

    2011-02-01

    Full Text Available Microscopy cell image analysis is a fundamental tool for biological research. This analysis is used in studies of different aspects of cell cultures. Visual inspection of individual cells is very time consuming, insufficient to detect or describe delicate changes in cellular morphology. The main challenges in segmenting nuclei in histometry are due to the fact that the specimen is a 2-D section of a 3-D tissue sample. The 2-D sectioning can result in partially imaged nuclei, sectioning of nuclei at odd angles, and damage due to the sectioning process. Furthermore, sections have finite thickness resulting in aggregating or overlapping nuclei in planar images. Hence a set of image objects that differ considerably from the ideal of round blob-like shapes occur. Their sizes and shapes in images can be irregular. The classic methodology for cell detection is image segmentation, which is a fundamental and difficult problem in computer vision. Image segmentation is a fundamental and difficult problem in computer vision. The difficulty in automatic segmentation of images of cells is often uneven due to auto fluorescence from the tissue and fluorescence from out-of-focus objects. This unevenness makes the separation of foreground and background a non-trivial task. The intensity variations within the nuclei further complicate the segmentation as the nuclei may be split into more than one object, leading to over-segmentation. Due to the cell nuclei are often clustered, make it difficult to separate the individual nuclei. Hence an automatic segmentation of cell nuclei is an essential step in image histometry and cytometry. This paper presents a robust method to segment clustered overlapping or aggregating nuclei cells using priori information of shape markers and marking function in a watershed-like algorithm. The shape markers are extracted using adaptive H-minima transform and prior information about the usual shape of normal/pathological nuclei cells. A

  2. Evolution of active galactic nuclei

    CERN Document Server

    Merloni, Andrea

    2012-01-01

    [Abriged] Supermassive black holes (SMBH) lurk in the nuclei of most massive galaxies, perhaps in all of them. The tight observed scaling relations between SMBH masses and structural properties of their host spheroids likely indicate that the processes fostering the growth of both components are physically linked, despite the many orders of magnitude difference in their physical size. This chapter discusses how we constrain the evolution of SMBH, probed by their actively growing phases, when they shine as active galactic nuclei (AGN) with luminosities often in excess of that of the entire stellar population of their host galaxies. Following loosely the chronological developments of the field, we begin by discussing early evolutionary studies, when AGN represented beacons of light probing the most distant reaches of the universe and were used as tracers of the large scale structure. This early study turned into AGN "Demography", once it was realized that the strong evolution (in luminosity, number density) of ...

  3. Multiple phonon excitation in nuclei

    International Nuclear Information System (INIS)

    The studies of multiphonon excitations in nuclei are reviewed both from the theoretical and experimental points of view. The presence of giant resonances in nuclei is described in the framework of macroscopic and microscopic models and the relative merits of different probes to excite such states are illustrated. The existence of giant resonances built on excited states is stressed. An exhaustive description of the theoretical estimates of the properties of the multiphonon states is presented. The theory predicts that such multiple collective excitations should closely follow a harmonic pattern. Recent experimental results on the double giant dipole resonance using the (π+π-) double charge exchange reaction are shown. The status of the search for isoscalar multiphonon excitations by means of the strong nuclear potential produced by heavy ions is presented. Conclusions are drawn and new prospects are discussed. (authors) 293 refs., 67 figs., 8 tabs

  4. Relativistic description of deformed nuclei

    International Nuclear Information System (INIS)

    The author has shown that relativistic Hartree calculations using parameters that have been fit to the properties of nuclear matter can provide a good description of both spherical and axially deformed nuclei. The quantitative agreement with experiment is equivalent to that which was obtained in non-relativistic calculations using Skyrme interactions. The equilibrium deformation is strongly correlated with the size of the spin-orbit splitting, and that parameter sets which give roughly the correct value for this splitting provide the best agreement with the quadrupole moments in the s-d shell. Finally, for closed shell +/- 1 nuclei, it was shown that the self-consistent calculations are able to reproduce the experimental magnetic moments. This was not possible in relativistic calculations which include only the effects of the valence orbital

  5. Moessbauer effects on oriented nuclei

    International Nuclear Information System (INIS)

    Standard nuclear orientation methods (not sensitive to the polarization) do not give information on the sign of the magnetic moment. Mossbauer effect separates right-hand and left-hand circularly polarized components, thus its detection on oriented nuclei (T approximately 10 mK) gives the sign of the magnetic moment of oriented state. In this thesis we applied this method to study the 3/2- ground states of 191Pt and 193Os, which are in the prolate-oblate transition region, where assignement of experimental levels to theoretical states is often umbiguous. We show that for those nuclei the sign of the magnetic moment is the signature of the configuration, and its determination establishes the correspondance between experimental and theoretical levels

  6. Phonon operators for deformed nuclei

    International Nuclear Information System (INIS)

    The mathematical formalism with the phonon operators independent of the signature of the angular momentum projection turns out to be inadequate for describing excited states of deformed nuclei. New phonon operators are introduced which depend on the signature of the angular momentum projection on the symmetry axis of a deformed nucleus. It is shown that the calculations with the new phonons take correctly into account the Pauli principle in two-phonon components of wave functions. The results obtained differ from those given by the phonons independent of the signature of the angular momentum projection. The new phonons must be used in deformed nuclei at taking systematically the Pauli principle into account and in calculations involving wave functions of excited states having components with more than one-phonon operator

  7. Compton Scattering on Light Nuclei

    Directory of Open Access Journals (Sweden)

    Shukla D.

    2010-04-01

    Full Text Available Compton scattering on light nuclei (A = 2, 3 has emerged as an effective avenue to search for signatures of neutron polarizabilities, both spin–independent and spin–dependent ones. In this discussion I will focus on the theoretical aspect of Compton scattering on light nuclei; giving first a brief overview and therafter concentrating on our Compton scattering calculations based on Chiral effective theory at energies of the order of pion mass. These elastic γd and γHe-3 calculations include nucleons, pions as the basic degrees of freedom. I will also discuss γd results where the ∆-isobar has been included explicitly. Our results on unpolarized and polarization observables suggest that a combination of experiments and further theoretical efforts will provide an extraction of the neutron polarizabilities.

  8. Phonon operators in deformed nuclei

    International Nuclear Information System (INIS)

    For the description of the excited states in deformed nuclei new phonon operators are introduced, which depend on the sign of the angular momentum projection onto the symmetry axis of a deformed nucleus. In the calculations with new phonons the Pauli principle is correctly taken into account in the two-phonon components of the wave functions. There is a difference in comparison with the calculation with phonons independent of the sign of the angular momentum projection. The new phonons should be used in deformed nuclei if the Pauli principle is consistently taken into account and in the calculations with the excited state wave functions having the components with more than one phonon operator

  9. Cooper pairs in atomic nuclei

    International Nuclear Information System (INIS)

    We describe recent efforts to study Cooper pairs in atomic nuclei. We consider a self-consistent Hartree Fock mean field for the even Sm isotopes and compare results based on three treatments of pairing correlations: a BCS treatment, a number-projected BCS treatment and an exact treatment using the Richardson Ansatz. Significant differences are seen in the pairing correlation energies. Furthermore, because it does not average over the properties of the fermion pairs, the Richardson solution permits a more meaningful definition of the Cooper wave function and of the fraction of pairs that are collective. Our results confirm that only a few pairs near the Fermi surface in realistic atomic nuclei are collective. (Author)

  10. Cooper pairs in atomic nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Pittel, S. [Bartol Research Institute and Department of Physics and Astronomy, University of Delaware, Newark, 19716 Delaware (United States); Dussel, G. G. [Departamento de Fisica J.J. Giambiagi, Universidad de Buenos Aires, 1428 Buenos Aires (Argentina); Dukelsky, J.; Sarriguren, P. [Instituto de Estructura de la Materia, CSIC, Serrano 123, 28006 Madrid (Spain)

    2008-12-15

    We describe recent efforts to study Cooper pairs in atomic nuclei. We consider a self-consistent Hartree Fock mean field for the even Sm isotopes and compare results based on three treatments of pairing correlations: a BCS treatment, a number-projected BCS treatment and an exact treatment using the Richardson Ansatz. Significant differences are seen in the pairing correlation energies. Furthermore, because it does not average over the properties of the fermion pairs, the Richardson solution permits a more meaningful definition of the Cooper wave function and of the fraction of pairs that are collective. Our results confirm that only a few pairs near the Fermi surface in realistic atomic nuclei are collective. (Author)

  11. Variability of Active Galactic Nuclei

    OpenAIRE

    Peterson, Bradley M.

    2001-01-01

    Continuum and emission-line variability of active galactic nuclei provides a powerful probe of microarcsecond scale structures in the central regions of these sources. In this contribution, we review basic concepts and methodologies used in analyzing AGN variability. We develop from first principles the basics of reverberation mapping, and pay special attention to emission-line transfer functions. We discuss application of cross-correlation analysis to AGN light curves. Finally, we provide a ...

  12. Direct Reactions with Exotic Nuclei

    International Nuclear Information System (INIS)

    We discuss recent work on Coulomb dissociation and an effective-range theory of low-lying electromagnetic strength of halo nuclei. We propose to study Coulomb dissociation of a halo nucleus bound by a zero-range potential as a homework problem. We study the transition from stripping to bound and unbound states and point out in this context that the Trojan-Horse method is a suitable tool to investigate subthreshold resonances

  13. Triaxial rotation in atomic nuclei

    Institute of Scientific and Technical Information of China (English)

    CHEN Yong-Shou; GAO Zao-Chun

    2009-01-01

    The Projected Shell Model has been developed to include the spontaneously broken axial symmetry so that the rapidly rotating triaxial nuclei can be described microscopically. The theory provides an useful tool to gain an insight into how a triaxial nucleus rotates, a fundamental question in nuclear structure. We shall address some current interests that are strongly associated with the triaxial rotation. A feasible method to explore the problem has been suggested.

  14. Neurotransmitters of the suprachiasmatic nuclei

    OpenAIRE

    Reghunandanan, Vallath; Reghunandanan, Rajalaxmy

    2006-01-01

    There has been extensive research in the recent past looking into the molecular basis and mechanisms of the biological clock, situated in the suprachiasmatic nuclei (SCN) of the anterior hypothalamus. Neurotransmitters are a very important component of SCN function. Thorough knowledge of neurotransmitters is not only essential for the understanding of the clock but also for the successful manipulation of the clock with experimental chemicals and therapeutical drugs. This article reviews the c...

  15. Weak pion production from nuclei

    Indian Academy of Sciences (India)

    S K Singh; M Sajjad Athar; Shakeb Ahmad

    2006-04-01

    The charged current pion production induced by neutrinos in 12C, 16O and 56Fe nuclei has been studied. The calculations have been done for the coherent as well as the incoherent processes assuming dominance and takes into account the effect of Pauli blocking, Fermi motion and the renormalization of in the nuclear medium. The pion absorption effects have also been taken into account.

  16. Direct Reactions with Exotic Nuclei

    CERN Document Server

    Baur, G

    2005-01-01

    We discuss recent work on Coulomb dissociation and an effective-range theory of low-lying electromagnetic strength of halo nuclei. We propose to study Coulomb dissociation of a halo nucleus bound by a zero-range potential as a homework problem. We study the transition from stripping to bound and unbound states and point out in this context that the Trojan-Horse method is a suitable tool to investigate subthreshold resonances.

  17. An introduction to mesic nuclei

    CERN Document Server

    Wilkin, Colin

    2016-01-01

    There is much speculation and a modest amount of evidence that certain mesons might form quasi-bound states with nuclei to produce really exotic states of matter. For this to be a practical possibility, the interaction between the meson and nucleons at low energies must be strong and attractive and the production rates "healthy". The conditions for this are surveyed for the light mesons. How this might lead to quasi-bound states is then discussed in a few typical cases.

  18. Weak pion production from nuclei

    International Nuclear Information System (INIS)

    The charged current pion production induced by neutrinos in 12C, 16O and 56Fe nuclei has been studied. The calculations have been done for the coherent as well as the incoherent processes assuming Δ dominance and takes into account the effect of Pauli blocking, Fermi motion and the renormalization of Δ in the nuclear medium. The pion absorption effects have also been taken into account. (author)

  19. Superheavy nuclei and fission barriers

    Science.gov (United States)

    Lu, Bing-Nan; Zhao, Jie; Zhao, En-Guang; Zhou, Shan-Gui

    In this chapter, we will present relativistic mean field (RMF) description of heavy and superheavy nuclei (SHN). We will discuss the shell structure and magic numbers in the mass region of SHN, binding energies and α decay Q values, shapes of ground states and potential energy surfaces and fission barriers. We particularly focus on the multidimensionally-constrained covariant density functional theories (CDFT) and the applications of CDFT to the study of exotic nuclear shapes and fission barriers.

  20. Geometric symmetries in light nuclei

    CERN Document Server

    Bijker, Roelof

    2016-01-01

    The algebraic cluster model is is applied to study cluster states in the nuclei 12C and 16O. The observed level sequences can be understood in terms of the underlying discrete symmetry that characterizes the geometrical configuration of the alpha-particles, i.e. an equilateral triangle for 12C, and a regular tetrahedron for 16O. The structure of rotational bands provides a fingerprint of the underlying geometrical configuration of alpha-particles.

  1. Proton scattering from unstable nuclei

    Indian Academy of Sciences (India)

    Y Blumenfeld; E Khan; F Maréchal; T Suomijärvi

    2001-08-01

    Recent improvements in the intensities and optical qualities of radioactive beams have made possible the study of elastic and inelastic proton scattering on unstable nuclei. The design and performances of an innovative silicon strip detector array devoted to such experiments are described. The quality of the data obtained are illustrated with recent results obtained at the GANIL facility for unstable oxygen, sulfur and argon isotopes. Methods to analyse the data using phenomenological and microscopic optical model potentials are discussed.

  2. PREFACE: Correlation Dynamics in Nuclei

    Science.gov (United States)

    Suzuki, Toshio; Otsuka, Takaharu; Ichimura, Munetake

    2005-01-01

    The International Symposium on `Correlation Dynamics in Nuclei' was held at the Sanjo Kaikan, the University of Tokyo, from the 31 January to 4 February 2005. This symposium was organized on the occasion of the 50th anniversary of the Configuration Mixing theory of Arima and Horie. The symposium was hosted by the University of Tokyo, and supported by the Inoue Foundation for Science, the Japan Atomic Energy Research Institute and the Ministry of Education, Culture, Sports, Science and Technology. The purpose of the symposium was to discuss theoretical and experimental developments and future prospects in physics of correlation dynamics in nuclei, including topics such as effective interactions, shell model studies of configuration mixing and spin-isospin modes in nuclei. It was shown in many ways and angles that the Arima-Horie theory has been a starting point of a variety of developments of the studies in these fields over many decades. The developments have been enhanced by the expansion of computational capabilities and the progress in accelerators, detectors and radioactive beam facilities. We enjoyed 28 excellent and lively invited talks and 30 oral presentations in the symposium with about 90 participants. A special session was dedicated to celebrate the 80th birthday of Professor Igal Talmi, who made invaluable and pioneering works in the shell model theory. Finally, we would like to thank all the speakers and the participants as well as the other organizers for their contributions which made the symposium very successful.

  3. Immunolcocalization of actin in intact and DNA—and histone—depleted nuclei and chromosomes of allium cepa

    Institute of Scientific and Technical Information of China (English)

    WANLIHONG; MIAOXING

    1998-01-01

    The presence of actin in eukaryotic nuclei and chromosomes,and especially in higher plant nuclei and chromosomes,has not been well established.We detected actin in meristematic cells of Allium cepa with indirect immunofluorescence technique and observed bright fluorescence in the intact nuclei and chromosomes,indicating that actin is present in the nuclei and chromosomes of the higher plant.We labeld sections of the meristematic cells of A.cepa with immunogold technique,gold parti cles were concentrated in condensed chromatin and nucleoli,confirming the results of the immunofluoresence observations.We traeated the nuclei and chromosomes of A.cepa with DNase I and 2M NaCl and obtained DNA-and histone-depleted nuclei and chromosomes.Indirect immunofluorescence tests showed that the DNA-and histonedepleted nuclei and chromosomes reacted positively with the anti-actin antibodies.These results demonstrate that the anti-actin antibodies.These results demonstrate that actin exists not only in intact nuclei and chromosomes,but also in DNA-and histone-depleted nuclei and chrmosomes of the plant.In addition,our immuno-fluorescence tests indicate that tropomyosin is present in the nuclei and chromosomes of A.cepa.

  4. Review on theoretical researches of superheavy nuclei

    International Nuclear Information System (INIS)

    We review the recent progress of theoretical researches on heavy nuclei and superheavy nuclei. At first we analyze the experimental data of long lifetime heavy nuclei and discuss their stability. Then the calculated binding energies and alpha-decay energies of heavy and superheavy nuclei from different models are compared and discussed. This includes the results from the local binding energy formula of heavy nuclei with Z ≥ 90 and N ≥ 130, those from the relativistic mean-field model, and from other models. For the local binding energy formula, it can reproduce experimental binding energies of known heavy and superheavy nuclei well. The relativistic mean-field model and non-relativistic mean-field model show that there is shape coexistence in superheavy nuclei. For some superheavy nuclei, superdeformed prolate shape can be their ground states and there are isomers in lowly excited states due to shape coexistence. The properties of some unknown superheavy nuclei are predicted. Some new views on the stability and on half-lives of heavy and superheavy nuclei are presented. Possible new phenomenon in superheavy region is analyzed and discussed. (author)

  5. The major nucleoside triphosphatase in pea (Pisum sativum L.) nuclei and in rat liver nuclei share common epitopes also present in nuclear lamins

    Science.gov (United States)

    Tong, C. G.; Dauwalder, M.; Clawson, G. A.; Hatem, C. L.; Roux, S. J.

    1993-01-01

    The major nucleoside triphosphatase (NTPase) activities in mammalian and pea (Pisum sativum L.) nuclei are associated with enzymes that are very similar both biochemically and immunochemically. The major NTPase from rat liver nuclei appears to be a 46-kD enzyme that represents the N-terminal portion of lamins A and C, two lamina proteins that apparently arise from the same gene by alternate splicing. Monoclonal antibody (MAb) G2, raised to human lamin C, both immunoprecipitates the major (47 kD) NTPase in pea nuclei and recognizes it in western blot analyses. A polyclonal antibody preparation raised to the 47-kD pea NTPase (pc480) reacts with the same lamin bands that are recognized by MAb G2 in mammalian nuclei. The pc480 antibodies also bind to the same lamin-like bands in pea nuclear envelope-matrix preparations that are recognized by G2 and three other MAbs known to bind to mammalian lamins. In immunofluorescence assays, pc480 and anti-lamin antibodies stain both cytoplasmic and nuclear antigens in plant cells, with slightly enhanced staining along the periphery of the nuclei. These results indicate that the pea and rat liver NTPases are structurally similar and that, in pea nuclei as in rat liver nuclei, the major NTPase is probably derived from a lamin precursor by proteolysis.

  6. Exotic light nuclei and nuclei in the lead region

    International Nuclear Information System (INIS)

    Three methods are discussed for modifying, or renormalizing, a truncated nuclear hamiltonian such that the wave functions obtained by diagonalizing this modified or effective hamiltoniandescribe the nucleus as well as possible: deriving the hamiltonian directly from a realistic nucleon-nucleon interaction between free nucleons; parametrizing the hamiltonian in terms of a number of parameters and determining these parameters from a least-squares fit of calculated properties to experimental data; approximating the nucleon-nucleon (NN) interaction between two nucleons in a nucleus by a simple analytic expression. An effective hamiltonian derived following the second method is applied in a theoretical study of exotic nuclei in the region of Z=2-9 and A=4-30 and the problem of the neutron halo in 11Li is discussed. Results of shell-model calculations of 20iPb and nuclei in its neighbourhood are presented in which an effective hamiltonian was employed derived with the last method. The quenching of M1 strength in 208Pb, and the spectroscopic factors measured in proton knock-out reactions could be described quite satisfactory. Finally, a method is presented for deriving the effective hamiltonian directly from the realistic NN interaction with algebraic techniques. (H.W.). 114 refs.; 34 figs.; 12 tabs.; schemes

  7. Effect of serum from rats with destructed nuclei of the posterior hypothalamus on the formation of hemopoietic colonies in the spleen of lethally irradiated mice after bone marrow cell transplantation

    International Nuclear Information System (INIS)

    Colony formation capability of serum from animals with destructed nuclei of the posterior hypothalamus was studied in lethally irradiated mice. Male-rats of Wistar line and hybrid mice (CBA x C57 BL) were used in the experiments. The serum from rats with destructed nuclei of the posterior hypothalamus was injected simultaneously with bone marrow transplantation into lethally irradiated mice. The number of macrocolonies in the spleen was counted on the 9th day. It was ascertained that the serum from rats with destructed nuclei of the posterior hypothalamus caused an increase of the number of macroscopically visible colonies in the spleen of lethally irradiated mice. The determination of hemopoetic types of colonies showed that the effect of the serum from those animals caused an increase of the number of granulocytic-type colonies. The initiation of colony stimulating and leukopoetic activity in the blood of animals after the destruction of mammillary body nuclei and posterior hypothalamic nucleus attested, according to the authors point of view, that humoral mediators (humoral mediator) could participated in the mechanism of hypothalamus effect on leulopoiesis

  8. Permutation group in light nuclei

    International Nuclear Information System (INIS)

    From general features of the multiplet scheme, a framework is provided for the application of permutation groups to the structure of light nuclei. It is shown that the description of nuclear states in terms of cluster configurations offers possibilities of finding the best orbital states for a given partition f. The significance of the orbital partition for orbital states is explained in terms of selection rules. Specific methods and results obtained in shell configurations, cluster configurations, and nuclear reactions are discussed. (2 figures, 4 tables, 42 references) (U.S.)

  9. Nucleon transfer between heavy nuclei

    International Nuclear Information System (INIS)

    Nucleon transfer reactions between heavy nuclei are characterized by the classical behaviour of the scattering orbits. Thus semiclassical concepts are well suited for the description of these reactions. In the present contribution the characteristics of single and multinucleon transfer reactions at energies below and above the Coulomb barrier are shown for systems like Sn+Sn, Xe+U and Ni+Pb. The role of the pairing interaction in the transfer of nucleon pairs is illustrated. For strong transitions the coupling of channels and the absorption into more complicated channels is taken into account in a coupled channels calculation

  10. Superdeformation in the bismuth nuclei

    International Nuclear Information System (INIS)

    High angular-momentum states in 196,197Bi were populated in the reaction 183W (19F,xn) at a beam energy of 108 MeV, and γ rays were detected with the Gammasphere array. Two weakly populated rotational bands, with energy spacings characteristic of superdeformation have been found. Both cascades can be assigned unambiguously to the Bi nuclei; however, their isotopic assignment to 197Bi is tentative. The properties of the bands and their possible structures are discussed. Our results represent the first identification of superdeformed bands in a nucleus of the A∼190 mass region with Z>82

  11. New Magicity of Light Nuclei

    OpenAIRE

    Samanta, C.; Adhikari, S

    2001-01-01

    A new mass formula capable of explaining the binding energies of almost all the known isotopes from Li to Bi is prescribed. In addition to identifying the new magic number at neutron number N=16 (Z=7-9), pseudo-magic numbers at N=14 (Z=7-10), Z=14 (N=13-19), and at N=6 (Z=3-8), the formula accounts for the loss of magicity for nuclei with N=8 (Z=4) and N=20 (Z=12-17). The redefinition of the neutron drip line resulting from this formula further allows us to predict the existence of 26O,31F, 3...

  12. Exotic nuclei and Yukawa's forces

    OpenAIRE

    Otsuka, Taka; Suzuki, Toshio; Utsuno, Yutaka

    2008-01-01

    In this plenary talk, we will overview the evolution of the shell structure in stable and exotic nuclei as a new paradigm of nuclear structure physics. This shell evolution is primarily due to the tensor force. The robust mechanism and some examples will be presented. Such examples include the disappearance of existing magic numbers and the appearance of new ones. The nuclear magic numbers have been believed, since Mayer and Jensen, to be constants as 2, 8, 20, 28, 50, …This turned out to be ...

  13. Collective bands in superdeformed nuclei

    International Nuclear Information System (INIS)

    The collective properties of excited superdeformed bands have been investigated in the framework of self-consistent cranked Nilsson plus quasiparticle random-phase approximation. The expected octupole nature of some bands observed recently in some nuclei has been confirmed by a comparative analysis of their E1 decays to the yrast band and of the anomalous behavior of their dynamical moment of inertia. It is also shown that the onset of supederformation affects considerably the structure of the giant resonances and greatly enhances the collectivity of the low-lying scissors mode. (author)

  14. Single Pion production from Nuclei

    International Nuclear Information System (INIS)

    We have studied charged current one pion production induced by νμ(ν-barμ) from some nuclei. The calculations have been done for the incoherent pion production processes from these nuclear targets in the Δ dominance model and take into account the effect of Pauli blocking, Fermi motion and renormalization of Δ properties in the nuclear medium. The effect of final state interactions of pions has also been taken into account. The numerical results have been compared with the recent results from the MiniBooNE experiment for the charged current 1π production, and also with some of the older experiments in Freon and Freon-Propane from CERN

  15. Microscopic properties of superdeformed nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Karlsson, Lennart B

    1999-04-01

    Many high spin rotational bands in superdeformed nuclei have been found in the A 140 - 150 region, but so far no linking transitions to known normal-deformed states have been found in these nuclei. Therefore, configuration and spin assignments have to be based on indirect spectroscopic information. Identical bands were first discovered in this region of superdeformed states. At present, some identical bands have also been found at normal deformation, but such bands are more common at superdeformation. Recently lifetime measurements have given relative quadrupole moments with high accuracy. Spectroscopic quantities are calculated using the configuration constrained cranked Nilsson-Strutinsky model with the modified oscillator potential. In a statistical study the occurrence of identical bands is tested. Comparing superdeformed and normal deformed nuclei, the higher possibility for identical bands at superdeformation is understood from calculated reduced widths of the E{sub {gamma}} and J{sup (2)} distributions. The importance of high-N orbitals for identical bands is also discussed. Additivity of electric quadrupole moment contributions in the superdeformed A - 150 region is discussed with the nucleus {sup 152}Dy as a `core`. In analytic harmonic oscillator calculations, the effective electric quadrupole moment q{sub eff}, i.e. the change in the total quadrupole moment caused by the added particle, is expressed as a simple function of the single-particle mass, quadrupole moment q{sub {nu}}. Also in realistic calculations, simple relations between q{sub eff} and q{sub {nu}} can be used to estimate the total electric quadrupole moment, e.g. for the nucleus {sup 142}Sm, by adding the effect of 10 holes, to the total electric quadrupole moment of {sup 152}Dy. Furthermore, tools are given for estimating the quadrupole moment for possible configurations in the superdeformed A - 150 region. For the superdeformed region around {sup 143}Eu, configuration and spin assignments

  16. Exotic nuclei: another aspect of nuclear structure

    International Nuclear Information System (INIS)

    This document gathers the lectures made at the Joliot Curie international summer school in 2002 whose theme that year was exotic nuclei. There were 11 contributions whose titles are: 1) interactions, symmetry breaking and effective fields from quarks to nuclei; 2) status and perspectives for the study of exotic nuclei: experimental aspects; 3) the pairing interaction and the N = Z nuclei; 4) borders of stability region and exotic decays; 5) shell structure of nuclei: from stability to decay; 6) variational approach of system with a few nucleons; 7) from heavy to super-heavy nuclei; 8) halos, molecules and multi-neutrons; 9) macroscopic approaches for fusion reactions; 10) beta decay: a tool for spectroscopy; 11) the gas phase chemistry of super-heavy elements

  17. Nuclei at the limits of particle stability

    International Nuclear Information System (INIS)

    The properties and synthesis of nuclei at the limits of particle stability are reviewed. Nuclear reactions were induced and studied by means of the 'exotic' nuclear beams, i.e. beams of radioactive drip-line nuclei. The beams are mostly generated in heavy-ion projectile fragmentation. The cases of both neutron-rich and proton-rich nuclei are discussed. (K.A.) 270 refs.; 13 figs.; 1 tab

  18. Otolith-Canal Convergence In Vestibular Nuclei Neurons

    Science.gov (United States)

    Dickman, J. David; Si, Xiao-Hong

    2002-01-01

    The current final report covers the period from June 1, 1999 to May 31, 2002. The primary objective of the investigation was to determine how information regarding head movements and head position relative to gravity is received and processed by central vestibular nuclei neurons in the brainstem. Specialized receptors in the vestibular labyrinths of the inner ear function to detect angular and linear accelerations of the head, with receptors located in the semicircular canals transducing rotational head movements and receptors located in the otolith organs transducing changes in head position relative to gravity or linear accelerations of the head. The information from these different receptors is then transmitted to central vestibular nuclei neurons which process the input signals, then project the appropriate output information to the eye, head, and body musculature motor neurons to control compensatory reflexes. Although a number of studies have reported on the responsiveness of vestibular nuclei neurons, it has not yet been possible to determine precisely how these cells combine the information from the different angular and linear acceleration receptors into a correct neural output signal. In the present project, rotational and linear motion stimuli were separately delivered while recording responses from vestibular nuclei neurons that were characterized according to direct input from the labyrinth and eye movement sensitivity. Responses from neurons receiving convergent input from the semicircular canals and otolith organs were quantified and compared to non-convergent neurons.

  19. Erythrocyte nuclei resemble dying neurons in embryonic dorsal root ganglia.

    Science.gov (United States)

    Coggeshall, R E; Pover, C M; Kwiat, G C; Fitzgerald, M

    1993-07-01

    Cell death or apoptosis is regarded as an important feature of mammalian neural development, but the evidence for this generalization depends on the assumption that cell death can be clearly recognized. The usual profile of a dying neuron is a deeply stained pyknotic homogeneous sphere. In this paper we present evidence that such profiles in embryonic rat T6 and L4 dorsal root ganglia are not dying neurons but rather nuclei of immature red blood cells. This observation, combined with recent work showing that the methods previously used for counting normal or dying neurons are biased, indicates that the classic work establishing the importance of apoptosis needs to be repeated. PMID:8233029

  20. Review of metastable states in heavy nuclei

    Science.gov (United States)

    Dracoulis, G. D.; Walker, P. M.; Kondev, F. G.

    2016-07-01

    The structure of nuclear isomeric states is reviewed in the context of their role in contemporary nuclear physics research. Emphasis is given to high-spin isomers in heavy nuclei, with A≳ 150 . The possibility to exploit isomers to study some of the most exotic nuclei is a recurring theme. In spherical nuclei, the role of octupole collectivity is discussed in detail, while in deformed nuclei the limitations of the K quantum number are addressed. Isomer targets and isomer beams are considered, along with applications related to energy storage, astrophysics, medicine, and experimental advances.

  1. Pairing correlations in exotic nuclei

    CERN Document Server

    Sagawa, H

    2012-01-01

    The BCS and HFB theories which can accommodate the pairing correlations in the ground states of atomic nuclei are presented. As an application of the pairing theories, we investigate the spatial extension of weakly bound Ne and C isotopes by taking into account the pairing correlation with the Hartree-Fock-Bogoliubov (HFB) method and a 3-body model, respectively. We show that the odd-even staggering in the reaction cross sections of $^{30,31,32}$Ne and $^{14,15,16}$C are successfully reproduced, and thus the staggering can be attributed to the unique role of pairing correlations in nuclei far from the stability line. A correlation between a one-neutron separation energy and the anti-halo effect is demonstrated for $s$- and p-waves using the HFB wave functions. We also propose effective density-dependent pairing interactions which reproduce both the neutron-neutron ($nn$) scattering length at zero density and the neutron pairing gap in uniform matter. Then, we apply these interactions to study pairing gaps in ...

  2. Mass-23 nuclei in astrophysics

    Science.gov (United States)

    Fraser, P. R.; Amos, K.; Canton, L.; Karataglidis, S.; Svenne, J. P.; van der Kniff, D.

    2015-09-01

    The formation of mass-23 nuclei by radiative capture is of great interest in astrophysics. A topical problem associated with these isobars is the so-called 22Na puzzle of ONe white dwarf novae, where the abundance of 22Na observed is not as is predicted by current stellar models, indicating there is more to learn about how the distribution of elements in the universe occurred. Another concerns unexplained variations in elements abundance on the surface of aging red giant stars. One method for theoretically studying nuclear scattering is the Multi-Channel Algebraic Scattering (MCAS) formalism. Studies to date have used a simple collective-rotor prescription to model the target states which couple to projectile nucleons. While, in general, the target states considered all belong to the ground state rotor band, for some systems it is necessary to include coupling to states outside of this band. Herein we discuss an extension of MCAS to allow coupling of different strengths between such states and the ground state band. This consideration is essential when studying the scattering of neutrons from 22Ne, a necessary step in studying the mass-23 nuclei mentioned above.

  3. Selfconsistent calculations for hyperdeformed nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Molique, H.; Dobaczewski, J.; Dudek, J.; Luo, W.D. [Universite Louis Pasteur, Strasbourg (France)

    1996-12-31

    Properties of the hyperdeformed nuclei in the A {approximately} 170 mass range are re-examined using the self-consistent Hartree-Fock method with the SOP parametrization. A comparison with the previous predictions that were based on a non-selfconsistent approach is made. The existence of the {open_quotes}hyper-deformed shell closures{close_quotes} at the proton and neutron numbers Z=70 and N=100 and their very weak dependence on the rotational frequency is suggested; the corresponding single-particle energy gaps are predicted to play a role similar to that of the Z=66 and N=86 gaps in the super-deformed nuclei of the A {approximately} 150 mass range. Selfconsistent calculations suggest also that the A {approximately} 170 hyperdeformed structures have neglegible mass asymmetry in their shapes. Very importantly for the experimental studies, both the fission barriers and the {open_quotes}inner{close_quotes} barriers (that separate the hyperdeformed structures from those with smaller deformations) are predicted to be relatively high, up to the factor of {approximately}2 higher than the corresponding ones in the {sup 152}Dy superdeformed nucleus used as a reference.

  4. Plasmid DNA entry into postmitotic nuclei of primary rat myotubes.

    OpenAIRE

    Dowty, M E; Williams, P; Zhang, G.; Hagstrom, J E; Wolff, J A

    1995-01-01

    These studies were initiated to elucidate the mechanism of DNA nuclear transport in mammalian cells. Biotin- or gold-labeled plasmid and plasmid DNA expression vectors for Escherichia coli beta-galactosidase or firefly luciferase were microinjected into the cytoplasm of primary rat myotubes in culture. Plasmid DNA was expressed in up to 70% of the injected myotubes, which indicates that it entered intact, postmitotic nuclei. The nuclear transport of plasmid DNA occurred through the nuclear po...

  5. [Synthesis of nicotinamide adenine dinucleotide in the nuclei of pigeon erythrocytes].

    Science.gov (United States)

    Nemchinskaia, V L; Makarova, T G; Mozhenok, T P; Braun, A D

    1975-08-01

    The nuclei of pigeon erythrocytes are capable of synthesizing NAD from nicotinamid-mononucleotides and ATP. Some data on the kinetics of NAD-pyrophosphorylase have been obtained: the optimal concentration of nuclei and the effect of various incubation time. The pretreatment of nuclei by Triton X-100, or by ultrasonics enhances NAD synthesis. The results suggest that cyclic 3',5'-AMP (Fluka) may have no effect on NAD synthesis. The control of the cell metabolism by NAD formation is considered. PMID:181878

  6. The asymptotic hadron spectrum, anti-nuclei, hyper-nuclei and quark phase

    International Nuclear Information System (INIS)

    The only hope of determining the hadronic spectrum in the high mass region is through a study of matter produced in very high energy nuclear collisions. Along the way, exotic nuclei, i.e., anti-nuclei and hyper-nuclei may be produced in appreciable numbers, and the detection of a quark phase may be possible. (orig.)

  7. Induction of apoptosis in purified animal and plant nuclei by Xenopus egg extracts

    Institute of Scientific and Technical Information of China (English)

    JIANGZHENGFAN; SHANZHU; 等

    1999-01-01

    We have developed a cell-free system that can trigger the nuclei purified from mouse liver and suspensioncultured carrot cells to undergo apoptosis as defined by the formation of apoptotic bodies and nucleosomal DNA fragments.The effects of different divalent cations and cycloheximide on DNA cleavage in this system were assessed.The fact that nuclei of plant cells can be induced to undergo apoptosis in a cell-free animal system suggests that animals and plants share a common signal transduction pathway triggering in the initiation stage of apoptosis.

  8. PECULIARITIES OF THE CEREBELLUM NUCLEI IN AGED PERSONS.

    Science.gov (United States)

    Shyian, D; Galata, D; Potapov, S; Gargin, V

    2016-04-01

    The study of the clinical anatomy and functional features of the cortex, subcortical and conductive pathways of the cerebellum is necessary for clinicians for elaboration rational surgical approaches to these formations, for determination the localization of pathological processes associated with these formations. Cerebellar nucleus neurons are crucial to the olivo-cerebellar circuit as they provide the sole output of the entire cerebellum. The relationship between mobility and cognition in aging is well established, but the relationship between mobility and the structure and function of the aging brain is relatively unknown. In connection with the above, the purpose of our study was detection of the morphological characteristics of the cerebellum nuclei in aged persons. Study was performed on 48 specimens of the cerebellum from people (24 male and 24 female), who died at the age from 75 to 99 years due to diseases, which were not related to the central nervous system damaging. Formalin-fixed human hemispheres were dissected with the Ludwig and Klingler fiber dissection technique under x6 to x40 magnifications of binocular microscope Olympus BX41 (Japan). The morphological features of the human cerebellar nuclei were established. Namely, on the series of sections of the cerebellum in the horizontal, frontal and sagittal planes, as well as on the macro-microscopic preparations of the cerebellar nuclei location, their relative position, shape, linear dimensions, weight and volume were described. The features of macro-microscopic and histological structure of the nuclei of the cerebellum were made own classification of the gyri and teeth of the dentate nucleus of the cerebellum was offered. Macro-microscopic dissection of persons died after 75 years old show no significant variability of linear dimensions of cerebellar nuclei with their specific location and options. Simultaneously, reliable reducing of cellular density was detected for Purkinje, granule and basket

  9. Short range correlations in nuclei

    International Nuclear Information System (INIS)

    Studying nucleon-nucleon (NN) correlated pairs will teach us a great deal about the high momentum part of the nuclear wave function,the short range part of the NN interaction, and the nature of cold dense nuclear matter. These correlations are similar in all nuclei, differing only in magnitude. High momentum nucleons, p > pfermi, all have a correlated partner with approximately equal and opposite momentum. At pair relative momenta of 300 rel < 500 MeV/c, these correlated pairs are dominated by tensor correlations. This is shown by the dominance of pn over pp pairs at pair total momentum and by the parity of pn to pp pairs at large pair total momentum. (author)

  10. Inclusive breakup of Borromean nuclei

    CERN Document Server

    Hussein, Mahir S; Frederico, Tobias

    2016-01-01

    We derive the inclusive breakup cross section of a three-fragment projectile nuclei, $a = b +x_1 + x_2$, in the spectator model. The resulting four-body cross section for observing $b$, is composed of the elastic breakup cross section which contains information about the correlation between the two participant fragments, and the inclusive non-elastic breakup cross section. This latter cross section is found to be a non-trivial four-body generalization of the Austern formula \\cite{Austern1987}, which is proportional to a matrix element of the form, $\\langle\\hat{\\rho}_{{x_1},{x_2}}\\left|\\left[W_{{x_1}} + W_{{x_2}} + W_{3B}\\right]\\right|\\hat{\\rho}_{{x_1}, {x_2}}\\rangle$. The new feature here is the three-body absorption, represented by the imaginary potential, $W_{3B}$. We analyze this type of absorption and supply ideas of how to calculate its contribution.

  11. Cavitation Nuclei: Experiments and Theory

    DEFF Research Database (Denmark)

    Mørch, Knud Aage

    2009-01-01

    The Swedish astrophysicist and Nobel Prize winner Hannes Alfven said: Theories come and go - the experiment is here forever. Often a theory, which we set up to describe an observed physical phenomenon, suffers from the lack of knowledge of decisive parameters, and therefore at best the theory...... becomes insufficient. Contrary, the experiment always reveals nature itself, though at prevailing experimental conditions. With essential parameters being out of control and even maybe unidentified, apparently similar experiments may deviate way beyond our expectations. However, these discrepancies offer...... us a chance to reflect on the character of the unknown parameters. In this way non-concordant experimental results may hold the key to the development of better theories - and to new experiments for the testing of their validity. Cavitation and cavitation nuclei are phenomena of that character....

  12. Precision experiments with exotic nuclei

    International Nuclear Information System (INIS)

    Progress and modern developments of secondary nuclear beam facilities based on the in-flight and ISOL separation methods are outlined. Precision experiments with nuclear beams characterized by large emittances have been performed by using special ion-optical conditions in spectrometers. A new generation of experiments have been started with stored and cooled exotic nuclei at sub-eV and at relativistic energies using the combination of an ISOL facility and an ion trap or the combination of an in-flight system with a storage and cooler ring, respectively. Both experimental scenarios are realized by ISOLDE and the ISOLTRAP at CERN and the fragment separator FRS in combination with the experimental storage ring ESR at GSI. The power and the potential of these devices are illustrated by direct mass and lifetime measurements. (orig.)

  13. Quasifree kaon photoproduction on nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Frank Lee; T. MART; Cornelius Bennhold; Lester Wright

    2001-12-01

    Investigations of the quasifree reaction A({gamma}, K Y)B are presented in the distorted wave impulse approximation (DWIA). For this purpose, we present a revised tree-level model of elementary kaon photoproduction that incorporates hadronic form factors consistent with gauge invariance, uses SU(3) values for the Born couplings and uses resonances consistent with multi-channel analyses. The potential of exclusive quasifree kaon photoproduction on nuclei to reveal details of the hyperon-nucleus interaction is examined. Detailed predictions for the coincidence cross section, the photon asymmetry, and the hyperon polarization and their sensitivities to the ingredients of the model are obtained for all six production channels. Under selected kinematics these observables are found to be sensitive to the hyperon-nucleus final state interaction. Some polarization observables are found to be insensitive to distortion effects, making them ideal tools to search for possible medium modifications of the elementary amplitude.

  14. Probing nuclei by stripping them

    International Nuclear Information System (INIS)

    The towing mode appears in nucleus collisions in which forward moving particles with specific angular correlations are emitted. In fact some particles are extracted from the target and towed along for a short while by the projectile during the collision. This process was discovered at the GANIL accelerator in the nineties. These collisions are peripheral. A simulation has shown that the energy and angle features of the particles emitted depends on their initial quantum state inside the target nucleus just before their emission which means that towing mode can be used as a tool to study quantum states in nuclei and their correlations. Experimental results concerning the following reactions: 11Be + 48Ti and 6He + Pb are presented. (A.C.)

  15. Decay of heavy and superheavy nuclei

    Indian Academy of Sciences (India)

    K P Santhosh

    2014-04-01

    We present here, an overview and progress of the theoretical works on the isomeric state decay, decay fine structure of even–even, even–odd, odd–even and odd–odd nuclei, a study on the feasibility of observing decay chains from the isotopes of the superheavy nuclei = 115 in the range 271 ≤ ≤ 294 and the isotopes of = 117 in the range 270 ≤ ≤ 301, within the Coulomb and proximity potential model for deformed nuclei (CPPMDN). The computed half-lives of the favoured and unfavoured decay of nuclei in the range 67 ≤ ≤ 91 from both the ground state and isomeric state, are in good agreement with the experimental data and the standard deviation of half-life is found to be 0.44. From the fine structure studies done on various ranges of nuclei, it is evident that, for nearly all the transitions, the theoretical values show good match with the experimental values. This reveals that CPPMDN is successful in explaining the fine structure of even–even, even–odd, odd–even and odd–odd nuclei. Our studies on the decay of the superheavy nuclei 271−294115 and 270−301117 predict 4 chains consistently from 284,285,286115 nuclei and 5 chains and 3 chains consistently from 288−291117 and 292117, respectively. We thus hope that these studies on 284−286115 and 288−292117 will be a guide to future experiments.

  16. RFP for the Comet Nuclei Tour (CONTOUR)

    DEFF Research Database (Denmark)

    Jørgensen, John Leif; Madsen, Peter Buch; Betto, Maurizio;

    1999-01-01

    This document describes the ASC Star Tracker (performance, functionality, requirements etc.) to The Johns Hopkins University - Applied Physics Laboratory for their Comet Nuclei TOUR (CONTOUR) Program.......This document describes the ASC Star Tracker (performance, functionality, requirements etc.) to The Johns Hopkins University - Applied Physics Laboratory for their Comet Nuclei TOUR (CONTOUR) Program....

  17. Etaprime interactions with nucleons and nuclei

    CERN Document Server

    Bass, Steven D

    2015-01-01

    We summarise recent progress in theory and experiment towards understanding etaprime meson interactions with nucleons and nuclei. Highlights include the production mechanism of etaprime mesons in proton-proton collisions close to threshold, the etaprime effective mass shift in nuclei and the determination of the etaprime-nucleon scattering length in free space.

  18. Mean-field models and exotic nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Bender, M.; Buervenich, T.; Maruhn, J.A.; Greiner, W. [Inst. fuer Theoretische Physik, Univ. Frankfurt (Germany); Rutz, K. [Inst. fuer Theoretische Physik, Univ. Frankfurt (Germany)]|[Gesellschaft fuer Schwerionenforschung mbH, Darmstadt (Germany); Reinhard, P.G. [Inst. fuer Theoretische Physik, Univ. Erlangen (Germany)

    1998-06-01

    We discuss two widely used nuclear mean-field models, the relativistic mean-field model and the (nonrelativistic) Skyrme-Hartree-Fock model, and their capability to describe exotic nuclei. Test cases are superheavy nuclei and neutron-rich Sn isotopes. New information in this regime helps to fix hitherto loosely determined aspects of the models. (orig.)

  19. Coupled-Cluster Theory for Nuclei

    International Nuclear Information System (INIS)

    The quantum-many body problem spans numerous scientific disciplines ranging from condensed matter to quantum dots, to high-temperature superconductors, and to nuclei. In these proceedings, we discuss the development of coupled-cluster techniques and their application to nuclei. We concentrate specifically on calculations pertaining to the ground- and excited-state properties of 4He and 16O

  20. Energy Radiation of the Active Galactic Nuclei

    Institute of Scientific and Technical Information of China (English)

    TANG Zhi-Ming; WANG Yong-Jiu

    2004-01-01

    In the Hellings-Nordtvedt theory, we obtain some expressions of energy radiation and mass defect effect for a kind of the active galactic nuclei, which is meaningful to calculating the energy radiation in the procession of forming this kind of celestial bodies. This calculation can give some interpretation for energy source of the jet from the active galactic nuclei.

  1. Total Nuclear Reaction Cross Section Induced by Halo Nuclei and Stable Nuclei

    Institute of Scientific and Technical Information of China (English)

    GUO Wen-Jun; JIANG Huan-Qing; LIU Jian-Ye; ZUO Wei; REN Zhong-Zhou; LEE Xi-Guo

    2003-01-01

    We develop a method for calculation of the total reaction cross sections induced by the halo nuclei and stable. nuclei. This approach is based on the Glauber theory, which is valid for nuclear reactions at high energies. It is extended for nuclear reactions at low energies and intermediate energies by including both the quantum correction and Coulomb correction under the assumption of the effective nuclear density distribution. The calculated results of the total reaction cross section induced by stable nuclei agree well with 30 experimental data within 10 percent accuracy. The comparison between the numerical results and 20 experimental data for the total nuclear reaction cross section induced by the neutron halo nuclei and the proton halo nuclei indicates a satisfactory agreement after considering the halo structure of these nuclei, which implies quite different mean fields for the nuclear reactions induced by halo nuclei and stable nuclei. The halo nucleon distributions and the root-mean-square radii of these nuclei can be extracted from the above comparison based on the improved Glauber model, which indicates clearly the halo structures of these nuclei. Especially,it is clear to see that the medium correction of the nucleon-nucleon collision has little effect on the total reaction cross sections induced by the halo nuclei due to the very weak binding and the very extended density distribution.

  2. Activation of raphe nuclei triggers rapid and distinct effects on parallel olfactory bulb output channels.

    Science.gov (United States)

    Kapoor, Vikrant; Provost, Allison C; Agarwal, Prateek; Murthy, Venkatesh N

    2016-02-01

    The serotonergic raphe nuclei are involved in regulating brain states over timescales of minutes and hours. We examined more rapid effects of raphe activation on two classes of principal neurons in the mouse olfactory bulb, mitral and tufted cells, which send olfactory information to distinct targets. Brief stimulation of the raphe nuclei led to excitation of tufted cells at rest and potentiation of their odor responses. While mitral cells at rest were also excited by raphe activation, their odor responses were bidirectionally modulated, leading to improved pattern separation of odors. In vitro whole-cell recordings revealed that specific optogenetic activation of raphe axons affected bulbar neurons through dual release of serotonin and glutamate. Therefore, the raphe nuclei, in addition to their role in neuromodulation of brain states, are also involved in fast, sub-second top-down modulation similar to cortical feedback. This modulation can selectively and differentially sensitize or decorrelate distinct output channels. PMID:26752161

  3. RADIO VARIABILITY IN SEYFERT NUCLEI

    International Nuclear Information System (INIS)

    Comparison of 8.4 GHz radio images of a sample of eleven, early-type Seyfert galaxies with previous observations reveals possible variation in the nuclear radio flux density in five of them over a seven year period. Four Seyferts (NGC 2110, NGC 3081, MCG -6-30-15, and NGC 5273) show a decline in their 8.4 GHz nuclear flux density between 1992 and 1999, while one (NGC 4117) shows an increase; the flux densities of the remaining six Seyferts (Mrk 607, NGC 1386, Mrk 620, NGC 3516, NGC 4968, and NGC 7465) have remained constant over this period. New images of MCG -5-23-16 are also presented. We find no correlation between radio variability and nuclear radio luminosity or Seyfert nuclear type, although the sample is small and dominated by type 2 Seyferts. Instead, a possible correlation between the presence of nuclear radio variability and the absence of hundred parsec-scale radio emission is seen, with four out of five marginally resolved or unresolved nuclei showing a change in nuclear flux density, while five out of six extended sources show no nuclear variability despite having unresolved nuclear sources. NGC 2110 is the only source in our sample with significant extended radio structure and strong nuclear variability (∼38% decline in nuclear flux density over seven years). The observed nuclear flux variability indicates significant changes are likely to have occurred in the structure of the nucleus on scales smaller than the VLA beam size (i.e., within the central ∼0.''1 (15 pc)), between the two epochs, possibly due to the appearance and fading of new components or shocks in the jet, consistent with previous detection of subparsec-scale nuclear structure in this Seyfert. Our results suggest that all Seyferts may exhibit variation in their nuclear radio flux density at 8.4 GHz, but that variability is more easily recognized in compact sources in which emission from the variable nucleus is not diluted by unresolved, constant flux density radio jet emission

  4. Symmetry and Phase Transitions in Nuclei

    International Nuclear Information System (INIS)

    Phase transitions in nuclei have received considerable attention in recent years, especially after the discovery that, contrary to expectations, systems at the critical point of a phase transition display a simple structure. In this talk, quantum phase transitions (QPT), i.e. phase transitions that occur as a function of a coupling constant that appears in the quantum Hamiltonian, H, describing the system, will be reviewed and experimental evidence for their occurrence in nuclei will be presented. The phase transitions discussed in the talk will be shape phase transitions. Different shapes have different symmetries, classified by the dynamic symmetries of the Interacting Boson Model, U(5), SU(3) and SO(6). Very recently, the concept of Quantum Phase Transitions has been extended to Excited State Quantum Phase Transitions (ESQPT). This extension will be discussed and some evidence for incipient ESQPT in nuclei will be presented. Systems at the critical point of a phase transition are called 'critical systems'. Approximate analytic formulas for energy spectra and other properties of 'critical nuclei', in particular for nuclei at the critical point of the second order U(5)-SO(6) transition, called E(5), and along the line of first order U(5)-SU(3) transitions, called X(5), will be presented. Experimental evidence for 'critical nuclei' will be also shown. Finally, the microscopic derivation of shape phase transitions in nuclei within the framework of density functional methods will be briefly discussed.(author)

  5. Cluster structure of nuclei based on AMD

    International Nuclear Information System (INIS)

    The technique of cooling the energy of the system being examined by using molecular dynamics is utilized for multi-dimensional variation calculation in the fields of physical properties and chemistry. By simulating the cooling of a finite nucleon system, the ground state of atomic nuclei can be studied. By antisymmetrized molecular dynamics, as for the ordinary nuclei with proton number Z=2n and neutron number N=2n, the cluster structure is examined. Further, the nuclei with excess neutrons, to which attention has been paid recently, are examined, and the feature of the systems with different Z and N are noticed. As to AMD method, the wave function, the ground state and the extension of the wave function are explained. AMD was applied to the even-even nuclei of A=4n. The results of density distribution are shown. It is known that most of 4n nuclei are constituted with the basic unit of alpha cluster. In the atomic nuclei with 4 nucleons in a closed shell, they have the developed cluster structure. The various internal deformation corresponding to the number of nucleons was observed. In the nuclei with excess neutrons Z< N, because the shell structures of protons and neutrons are different, the overall structure is determined by respective effects. The dependence of nuclear structure on the number of neutrons is reported. (K.I.)

  6. Fusion probability in heavy nuclei

    Science.gov (United States)

    Banerjee, Tathagata; Nath, S.; Pal, Santanu

    2015-03-01

    Background: Fusion between two massive nuclei is a very complex process and is characterized by three stages: (a) capture inside the potential barrier, (b) formation of an equilibrated compound nucleus (CN), and (c) statistical decay of the CN leading to a cold evaporation residue (ER) or fission. The second stage is the least understood of the three and is the most crucial in predicting yield of superheavy elements (SHE) formed in complete fusion reactions. Purpose: A systematic study of average fusion probability, , is undertaken to obtain a better understanding of its dependence on various reaction parameters. The study may also help to clearly demarcate onset of non-CN fission (NCNF), which causes fusion probability, PCN, to deviate from unity. Method: ER excitation functions for 52 reactions leading to CN in the mass region 170-220, which are available in the literature, have been compared with statistical model (SM) calculations. Capture cross sections have been obtained from a coupled-channels code. In the SM, shell corrections in both the level density and the fission barrier have been included. for these reactions has been extracted by comparing experimental and theoretical ER excitation functions in the energy range ˜5 %-35% above the potential barrier, where known effects of nuclear structure are insignificant. Results: has been shown to vary with entrance channel mass asymmetry, η (or charge product, ZpZt ), as well as with fissility of the CN, χCN. No parameter has been found to be adequate as a single scaling variable to determine . Approximate boundaries have been obtained from where starts deviating from unity. Conclusions: This study quite clearly reveals the limits of applicability of the SM in interpreting experimental observables from fusion reactions involving two massive nuclei. Deviation of from unity marks the beginning of the domain of dynamical models of fusion. Availability of precise ER cross sections over a wider energy range for

  7. A new spin on nuclei

    International Nuclear Information System (INIS)

    Magnetic rotation is a new phenomenon that is forcing physicists to rethink their understanding of what goes on inside the nucleus The rotation of quantum objects has a long and distinguished history in physics. In 1912 the Danish scientist Niels Bjerrum was the first to recognize that the rotation of molecules is quantized. In 1938 Edward Teller and John Wheeler observed similar features in the spectra of excited nuclei, and suggested that this was caused by the nucleus rotating. But a more complete explanation had to wait until 1951, when Aage Bohr (the son of Niels) pointed out that rotation was a consequence of the nucleus deforming from its spherical shape. We owe much of our current understanding of nuclear rotation to the work of Bohr and Ben Mottelson, who shared the 1975 Nobel Prize for Physics with James Rainwater for developing a model of the nucleus that combined the individual and collective motions of the neutrons and protons inside the nucleus. What makes it possible for a nucleus to rotate? Quantum mechanically, a perfect sphere cannot rotate because it appears the same when viewed from any direction and there is no point of reference against which its change in position can be detected. To see the rotation the spherical symmetry must be broken to allow an orientation in space to be defined. For example, a diatomic molecule, which has a dumbbell shape, can rotate about the two axes perpendicular to its axis of symmetry. A quantum mechanical treatment of a diatomic molecule leads to a very simple relationship between rotational energy, E, and angular momentum. This energy is found to be proportional to J(J + 1), where J is the angular momentum quantum number. The molecule also has a magnetic moment that is proportional to J. These concepts can be applied to the atomic nucleus. If the distribution of mass and/or charge inside the nucleus becomes non-spherical then the nucleus will be able to rotate. The rotation is termed ''collective'' because many

  8. Stability of the heaviest atomic nuclei

    International Nuclear Information System (INIS)

    Calculations of the alpha-decay and the spontaneous-fission of the heaviest nuclei are described. Main attention is given to the presentation of the results of the author, obtained in recent few years. One of the important modification, with respect to earlier studies, is the use of a multidimensional deformation space, which is especially important for the calculation of the fission barrier. Even-even nuclei with atomic number Z=92-110 are considered. Much attention is paid to the description of shell effects in the half-lives. These effects are especially important for the heaviest nuclei as they decide the question of their existence. (author)

  9. Properties of superheavy nuclei with Z = 124

    CERN Document Server

    Mehta, M S; Kumar, Bharat; Patra, S K

    2015-01-01

    We employ Relativistic Mean Field (RMF) model with NL3 parametrization to investigate the ground state properties of superheavy nucleus, Z = 124. The nuclei selected (from among complete isotopic series) for detailed investigation show that the nucleon density at the center is very low and therefore, these nuclei can be treated as semi-bubble nuclei. The considerable shell gap appears at neutron numbers N = 172, 184 and 198 showing the magicity corresponding to these numbers. The results are compared with the macro-microscopic Finite Range Droplet Model (FRDM) wherever possible.

  10. True ternary fission of superheavy nuclei

    OpenAIRE

    Zagrebaev, V.I.; A. V. Karpov; Greiner, Walter

    2010-01-01

    We found that a true ternary fission with formation of a heavy third fragment (a new type of radioactivity) is quite possible for superheavy nuclei due to the strong shell effects leading to a three-body clusterization with the two doubly magic tin-like cores. The simplest way to discover this phenomenon in the decay of excited superheavy nuclei is a detection of two tin-like clusters with appropriate kinematics in low-energy collisions of medium mass nuclei with actinide targets. The three-b...

  11. Brueckner-AMD Study of Light Nuclei

    International Nuclear Information System (INIS)

    We applied the Brueckner theory to the Antisymmetrized Molecular Dynamics (AMD) and examined the reliability of the AMD calculations based on realistic nuclear interactions. In this method, the Bethe-Goldstone equation in the Brueckner theory is solved for every nucleon pair described by wave packets of AMD, and the G-matrix is calculated with single-particle orbits in AMD self-consistently. We apply this framework to not only α-nuclei but also N≠Z nuclei with A∼10. It is confirmed that these results present the description of reasonable cluster structures and energy-level schemes comparable with the experimental ones in light nuclei.

  12. Molecular outflows in starburst nuclei

    CERN Document Server

    Roy, Arpita; Sharma, Prateek; Shchekinov, Yuri

    2016-01-01

    Recent observations have detected molecular outflows in a few nearby starburst nuclei. We discuss the physical processes at work in such an environment in order to outline a scenario that can explain the observed parameters of the phenomenon, such as the molecular mass, speed and size of the outflows. We show that outflows triggered by OB associations, with $N_{OB}\\ge 10^5$ (corresponding to a star formation rate (SFR)$\\ge 1$ M$_{\\odot}$ yr$^{-1}$ in the nuclear region), in a stratified disk with mid-plane density $n_0\\sim 200\\hbox{--}1000$ cm$^{-3}$ and scale height $z_0\\ge 200 (n_0/10^2 \\, {\\rm cm}^{-3})^{-3/5}$ pc, can form molecules in a cool dense and expanding shell. The associated molecular mass is $\\ge 10^7$ M$_\\odot$ at a distance of a few hundred pc, with a speed of several tens of km s$^{-1}$. We show that a SFR surface density of $10 \\le \\Sigma_{SFR} \\le 50$ M$_\\odot$ yr$^{-1}$ kpc$^{-2}$ favours the production of molecular outflows, consistent with observed values.

  13. Molecular outflows in starburst nuclei

    Science.gov (United States)

    Roy, Arpita; Nath, Biman B.; Sharma, Prateek; Shchekinov, Yuri

    2016-08-01

    Recent observations have detected molecular outflows in a few nearby starburst nuclei. We discuss the physical processes at work in such an environment in order to outline a scenario that can explain the observed parameters of the phenomenon, such as the molecular mass, speed and size of the outflows. We show that outflows triggered by OB associations, with NOB ≥ 105 (corresponding to a star formation rate (SFR)≥1 M⊙ yr-1 in the nuclear region), in a stratified disk with mid-plane density n0 ˜ 200-1000 cm-3 and scale height z0 ≥ 200(n0/102 cm-3)-3/5 pc, can form molecules in a cool dense and expanding shell. The associated molecular mass is ≥107 M⊙ at a distance of a few hundred pc, with a speed of several tens of km s-1. We show that a SFR surface density of 10 ≤ ΣSFR ≤ 50 M⊙ yr-1 kpc-2 favours the production of molecular outflows, consistent with observed values.

  14. Localization and dynamics of small circular DNA in live mammalian nuclei

    DEFF Research Database (Denmark)

    Mearini, Giulia; Nielsen, Peter E; Fackelmayer, Frank O

    2004-01-01

    While genomic DNA, packaged into chromatin, is known to be locally constrained but highly dynamic in the nuclei of living cells, little is known about the localization and dynamics of small circular DNA molecules that invade cells by virus infection, application of gene therapy vectors or...

  15. Subsets of Visceral Adipose Tissue Nuclei with Distinct Levels of 5-Hydroxymethylcytosine

    Science.gov (United States)

    Yu, Ping; Ji, Lexiang; Lee, Kevin J.; Yu, Miao; He, Chuan; Ambati, Suresh; McKinney, Elizabeth C.; Jackson, Crystal; Schmitz, Robert J.; Meagher, Richard B.

    2016-01-01

    The reprogramming of cellular memory in specific cell types, and in visceral adipocytes in particular, appears to be a fundamental aspect of obesity and its related negative health outcomes. We explored the hypothesis that adipose tissue contains epigenetically distinct subpopulations of adipocytes that are differentially potentiated to record cellular memories of their environment. Adipocytes are large, fragile, and technically difficult to efficiently isolate and fractionate. We developed fluorescence nuclear cytometry (FNC) and fluorescence activated nuclear sorting (FANS) of cellular nuclei from visceral adipose tissue (VAT) using the levels of the pan-adipocyte protein, peroxisome proliferator-activated receptor gamma-2 (PPARg2), to distinguish classes of PPARg2-Positive (PPARg2-Pos) adipocyte nuclei from PPARg2-Negative (PPARg2-Neg) leukocyte and endothelial cell nuclei. PPARg2-Pos nuclei were 10-fold enriched for most adipocyte marker transcripts relative to PPARg2-Neg nuclei. PPARg2-Pos nuclei showed 2- to 50-fold higher levels of transcripts encoding most of the chromatin-remodeling factors assayed, which regulate the methylation of histones and DNA cytosine (e.g., DNMT1, TET1, TET2, KDM4A, KMT2C, SETDB1, PAXIP1, ARID1A, JMJD6, CARM1, and PRMT5). PPARg2-Pos nuclei were large with decondensed chromatin. TAB-seq demonstrated 5-hydroxymethylcytosine (5hmC) levels were remarkably dynamic in gene bodies of various classes of VAT nuclei, dropping 3.8-fold from the highest quintile of expressed genes to the lowest. In short, VAT-derived adipocytes appear to be more actively remodeling their chromatin than non-adipocytes. PMID:27171244

  16. Preferential association of glycoproteins to the euchromatin regions of cross-fractured nuclei is revealed by fracture-label

    OpenAIRE

    1986-01-01

    We used fracture-label to establish ultrastructural localization of glycoproteins in cross-fractured nuclei of duodenal columnar and exocrine pancreatic cells. Mannose residues were detected in cell nuclei by labeling freeze-fractured tissues with concanavalin A- horseradish peroxidase X colloidal gold (Con A-HRP X CG) or direct concanavalin A X colloidal gold (Con A X CG); fucose residues were detected with Ulex Europaeus I X colloidal gold (UEA I X CG) markers. Areas of the three main intra...

  17. From Nucleons To Nuclei To Fusion Reactions

    Energy Technology Data Exchange (ETDEWEB)

    Quaglioni, S; Navratil, P; Roth, R; Horiuchi, W

    2012-02-15

    Nuclei are prototypes of many-body open quantum systems. Complex aggregates of protons and neutrons that interact through forces arising from quantum chromo-dynamics, nuclei exhibit both bound and unbound states, which can be strongly coupled. In this respect, one of the major challenges for computational nuclear physics, is to provide a unified description of structural and reaction properties of nuclei that is based on the fundamental underlying physics: the constituent nucleons and the realistic interactions among them. This requires a combination of innovative theoretical approaches and high-performance computing. In this contribution, we present one of such promising techniques, the ab initio no-core shell model/resonating-group method, and discuss applications to light nuclei scattering and fusion reactions that power stars and Earth-base fusion facilities.

  18. Understanding Nuclei in the upper sd - shell

    CERN Document Server

    Sarkar, M Saha; Ray, Sudatta; Kshetri, Ritesh; Sarkar, S

    2013-01-01

    Nuclei in the upper-$sd$ shell usually exhibit characteristics of spherical single particle excitations. In the recent years, employment of sophisticated techniques of gamma spectroscopy has led to observation of high spin states of several nuclei near A$\\simeq$ 40. In a few of them multiparticle, multihole rotational states coexist with states of single particle nature. We have studied a few nuclei in this mass region experimentally, using various campaigns of the Indian National Gamma Array setup. We have compared and combined our empirical observations with the large-scale shell model results to interpret the structure of these nuclei. Indication of population of states of large deformation has been found in our data. This gives us an opportunity to investigate the interplay of single particle and collective degrees of freedom in this mass region.

  19. Systematic study of shell gaps in nuclei

    CERN Document Server

    Mo, Qiuhong; Wang, Ning

    2014-01-01

    The nucleon separation energies and shell gaps in nuclei over the whole nuclear chart are systematically studied with eight global nuclear mass models. For unmeasured neutron-rich and super-heavy regions, the uncertainty of the predictions from these different mass models is still large. The latest version (WS4) of the Weizs\\"acker-Skyrme mass formula, in which the isospin dependence of model parameters is introduced into the macroscopic-microscopic approach inspired by the Skyrme energy-density functional, is found to be the most accurate one in the descriptions of nuclear masses, separation energies and shell gaps. Based on the predicted shell gaps in nuclei, the possible magic numbers in super-heavy nuclei region are investigated. In addition to the shell closures at $N=184, Z=114$, the sub-shell closures at around $N=178, Z=120$ could also play a role for the stability of super-heavy nuclei.

  20. Relativistic symmetry breaking in light kaonic nuclei

    CERN Document Server

    Yang, Rong-Yao; Xiang, Qian-Fei; Zhang, Dong-Rui; Wei, Si-Na

    2014-01-01

    As the experimental data from kaonic atoms and $K^{-}N$ scatterings imply that the $K^{-}$-nucleon interaction is strongly attractive at saturation density, there is a possibility to form $K^{-}$-nuclear bound states or kaonic nuclei. In this work, we investigate the ground-state properties of the light kaonic nuclei with the relativistic mean field theory. It is found that the strong attraction between $K^{-}$ and nucleons reshapes the scalar and vector meson fields, leading to the remarkable enhancement of the nuclear density in the interior of light kaonic nuclei and the manifest shift of the single-nucleon energy spectra and magic numbers therein. As a consequence, the pseudospin symmetry is shown to be violated together with enlarged spin-orbit splittings in these kaonic nuclei.

  1. Brueckner-AMD study of light nuclei

    International Nuclear Information System (INIS)

    In many states of light nuclei, the cluster structure is observed in addition to the shell structure. To understand the mechanism of clustering, we apply the Brueckner theory to the Antisymmetrized Molecular Dynamics (AMD) based on realistic nuclear interactions. The Bethe-Goldstone equation in the Brueckner theory is solved for every nucleon pair described by wave packets of AMD, and the G-matrix is calculated with single-particle orbits in AMD self-consistently. We show applicability of this method not only to self-conjugate nuclei but also to N ≠ Z nuclei with A ≤ 12. It is confirmed that these results present reasonable description of cluster structures and energy-level schemes in comparison with the experimental ones in light nuclei. For 8Be having a typical α + α cluster structure, the structure dependence of the G-matrix is investigated and the role of tensor force is shown to be important in understanding the clustering mechanism.

  2. Superheavy Nuclei: Relativistic Mean Field Outlook

    CERN Document Server

    Afanasjev, A V

    2006-01-01

    The analysis of quasiparticle spectra in heaviest $A\\sim 250$ nuclei with spectroscopic data provides an additional constraint for the choice of effective interaction for the description of superheavy nuclei. It strongly suggest that only the parametrizations of the relativistic mean field Lagrangian which predict Z=120 and N=172 as shell closures are reliable for superheavy nuclei. The influence of the central depression in the density distribution of spherical superheavy nuclei on the shell structure is studied. Large central depression produces large shell gaps at Z=120 and N=172. The shell gaps at Z=126 and N=184 are favored by a flat density distribution in the central part of nucleus. It is shown that approximate particle number projection (PNP) by means of the Lipkin-Nogami method removes pairing collapse seen at these gaps in the calculations without PNP.

  3. Superheavy nuclei: a relativistic mean field outlook

    International Nuclear Information System (INIS)

    The analysis of quasi-particle spectra in the heaviest A∼250 nuclei with spectroscopic data provides an additional constraint for the choice of effective interaction for the description of superheavy nuclei. It strongly suggests that only the parametrizations which predict Z = 120 and N = 172 as shell closures are reliable for superheavy nuclei within the relativistic mean field theory. The influence of the central depression in the density distribution of spherical superheavy nuclei on the shell structure is studied. A large central depression produces large shell gaps at Z = 120 and N = 172. The shell gaps at Z = 126 and N = 184 are favoured by a flat density distribution in the central part of the nucleus. It is shown that approximate particle number projection (PNP) by means of the Lipkin-Nogami (LN) method removes pairing collapse seen at these gaps in the calculations without PNP

  4. Perspectives of production of superheavy nuclei

    Science.gov (United States)

    Adamian, G. G.; Antonenko, N. V.; Bezbakh, A. N.; Sargsyan, V. V.; Scheid, W.

    2016-07-01

    Possible ways of production of superheavies are discussed. Impact of nuclear structure on the production of superheavy nuclei in complete fusion reactions is discussed. The proton shell closure at Z = 120 is discussed.

  5. Physics with nuclei at high energies

    International Nuclear Information System (INIS)

    Physics with nuclei at high energy is not reducible to a superposition of interactions involving individual nucleons; rather, qualitatively new phenomena show up. This is what one concludes from recent data on dilepton production off nuclei and on elastic proton-nucleus scattering. Furthermore, recent analyses of ion collisions at BNL and CERN reveal a number of non-conventional features. The relevant contributions to this Rencontre are summarized here. 37 refs., 16 figs

  6. Synthesis of superheavy nuclei: Obstacles and opportunities

    Directory of Open Access Journals (Sweden)

    Zagrebaev V.I.

    2015-01-01

    Full Text Available There are only 3 methods for the production of heavy and superheavy (SH nuclei, namely, fusion reactions, a sequence of neutron capture and beta(- decay and multinucleon transfer reactions. Low values of the fusion cross sections and very short half-lives of nuclei with Z<120 put obstacles in synthesis of new elements. At the same time, an important area of SH isotopes located between those produced in the cold and hot fusion reactions remains unstudied yet. This gap could be filled in fusion reactions of 48Ca with available lighter isotopes of Pu, Am, and Cm. New neutron-enriched isotopes of SH elements may be produced with the use of a 48Ca beam if a 250Cm target would be prepared. In this case we get a real chance to reach the island of stability owing to a possible beta(+ decay of 291114 and 287112 nuclei formed in this reaction with a cross section of about 0.8 pb. A macroscopic amount of the long-living SH nuclei located at the island of stability may be produced by using the pulsed nuclear reactors of the next generation only if the neutron fluence per pulse will be increased by about three orders of magnitude. Multinucleon transfer processes look quite promising for the production and study of neutron-rich heavy nuclei located in upper part of the nuclear map not reachable by other reaction mechanisms. Reactions with actinide beams and targets are of special interest for synthesis of new neutron-enriched transfermium nuclei and not-yet-known nuclei with closed neutron shell N=126 having the largest impact on the astrophysical r-process. The estimated cross sections for the production of these nuclei allows one to plan such experiments at currently available accelerators.

  7. Synthesis of superheavy nuclei: Obstacles and opportunities

    Science.gov (United States)

    Zagrebaev, V. I.; Karpov, A. V.; Greiner, Walter

    2015-01-01

    There are only 3 methods for the production of heavy and superheavy (SH) nuclei, namely, fusion reactions, a sequence of neutron capture and beta(-) decay and multinucleon transfer reactions. Low values of the fusion cross sections and very short half-lives of nuclei with Zcold and hot fusion reactions remains unstudied yet. This gap could be filled in fusion reactions of 48Ca with available lighter isotopes of Pu, Am, and Cm. New neutron-enriched isotopes of SH elements may be produced with the use of a 48Ca beam if a 250Cm target would be prepared. In this case we get a real chance to reach the island of stability owing to a possible beta(+) decay of 291114 and 287112 nuclei formed in this reaction with a cross section of about 0.8 pb. A macroscopic amount of the long-living SH nuclei located at the island of stability may be produced by using the pulsed nuclear reactors of the next generation only if the neutron fluence per pulse will be increased by about three orders of magnitude. Multinucleon transfer processes look quite promising for the production and study of neutron-rich heavy nuclei located in upper part of the nuclear map not reachable by other reaction mechanisms. Reactions with actinide beams and targets are of special interest for synthesis of new neutron-enriched transfermium nuclei and not-yet-known nuclei with closed neutron shell N=126 having the largest impact on the astrophysical r-process. The estimated cross sections for the production of these nuclei allows one to plan such experiments at currently available accelerators.

  8. Determining properties of baryon resonances in nuclei

    International Nuclear Information System (INIS)

    Meson-nucleus and photon-nucleus interactions are important sources of information about the medium modifications of baryon resonances in nuclei. Indications of how large the medium effects are for resonances above the Δ33(1232) are provided by it combined analysis of photonuclear and pion cross sections in the GeV range of energies. Tile existing data indicate a possible 10-20% renormalization of the pion coupling to higher-lying resonances in nuclei

  9. Cosmic Ray Nuclei (CRN) detector investigation

    Science.gov (United States)

    Meyer, Peter; Muller, Dietrich; Lheureux, Jacques; Swordy, Simon

    1991-01-01

    The Cosmic Ray Nuclei (CRN) detector was designed to measure elemental composition and energy spectra of cosmic radiation nuclei ranging from lithium to iron. CRN was flown as part of Spacelab 2 in 1985, and consisted of three basic components: a gas Cerenkov counter, a transition radiation detector, and plastic scintillators. The results of the experiment indicate that the relative abundance of elements in this range, traveling at near relativistic velocities, is similar to those reported at lower energy.

  10. Relativistic symmetry breaking in light kaonic nuclei

    OpenAIRE

    Yang, Rong-Yao; Jiang, Wei-Zhou; Xiang, Qian-Fei; Zhang, Dong-Rui; Wei, Si-Na

    2014-01-01

    As the experimental data from kaonic atoms and $K^{-}N$ scatterings imply that the $K^{-}$-nucleon interaction is strongly attractive at saturation density, there is a possibility to form $K^{-}$-nuclear bound states or kaonic nuclei. In this work, we investigate the ground-state properties of the light kaonic nuclei with the relativistic mean field theory. It is found that the strong attraction between $K^{-}$ and nucleons reshapes the scalar and vector meson fields, leading to the remarkabl...

  11. Shell structure of nuclei far from stability

    Energy Technology Data Exchange (ETDEWEB)

    Grave, H. [Gesellschaft fuer Schwerionenforschung mbH, Darmstadt (Germany); Lewitowicz, M. [Grand Accelerateur National d' Ions Lourds (GANIL), 14 - Caen (France)

    2001-03-01

    The experimental status of shell structure studies in medium-heavy nuclei far off the line of {beta}-stability is reviewed. Experimental techniques, signatures for shell closure and expectations for future investigations are discussed for the key regions around {sup 48,56}Ni, {sup 100}Sn for proton rich nuclei and neutron-rich N=20 isotones, Ca, Ni and Sn isotopes. (authors)

  12. Effective Field Theory for Lattice Nuclei

    OpenAIRE

    Barnea, N.; Contessi, L.; Gazit, D.; Pederiva, F.; van Kolck, U.

    2013-01-01

    We show how nuclear effective field theory (EFT) and ab initio nuclear-structure methods can turn input from lattice quantum chromodynamics (LQCD) into predictions for the properties of nuclei. We argue that pionless EFT is the appropriate theory to describe the light nuclei obtained in recent LQCD simulations carried out at pion masses much heavier than the physical pion mass. We solve the EFT using the effective-interaction hyperspherical harmonics and auxiliary-field diffusion Monte Carlo ...

  13. Strength of Coriolis alignment in actinide nuclei

    International Nuclear Information System (INIS)

    Analysis of aligned angular momenta i/sub α/(ω) in different rotational bands extracted from experimental data with a linear spin term approx.BI in the formulas for E/sub rot/(I) reveal that, in actinide nuclei in the levels with modest spin I< or =23, i/sub α/(ω) usually is very small (< or approx. =0.7), i.e., is much smaller than in rare earth nuclei

  14. Proton radioactivity from proton-rich nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Guzman, F.; Goncalves, M. [Instituto Superior de Ciencias y Tecnologia Nucleares (ISCTN), La Habana (Cuba); Tavares, O.A.P.; Duarte, S.B. [Centro Brasileiro de Pesquisas Fisicas (CBPF), Rio de Janeiro, RJ (Brazil); Garcia, F.; Rodriguez, O. [Sao Paulo Univ., SP (Brazil). Inst. de Fisica

    1999-03-01

    Half-lives for proton emission from proton-rich nuclei have been calculated by using the effective liquid drop model of heavy-particle decay of nuclei. It is shown that this model is able to offer results or spontaneous proton-emission half-life-values in excellent agreement with the existing experimental data. Predictions of half-life-values for other possible proton-emission cases are present for null orbital angular momentum. (author)

  15. Spectral fluctuation properties of spherical nuclei

    OpenAIRE

    Jafarizadeh, M. A.; Fouladi, N.; Sabri, H.

    2012-01-01

    The spectral fluctuation properties of spherical nuclei are considered by use of NNSD statistic. With employing a generalized Brody distribution included Poisson, GOE and GUE limits and also MLE technique, the chaoticity parameters are estimated for sequences prepared by all the available empirical data. The ML-based estimated values and also KLD measures propose a non regular dynamic. Also, spherical odd-mass nuclei in the mass region, exhibit a slight deviation to the GUE spectral statistic...

  16. Symmetries in nuclei and molecules

    International Nuclear Information System (INIS)

    Recent progress in two different fronts is reported. First, the concept of bisection of a harmonic oscillator or hydrogen atom, used in the past in establishing the connection between U(3) and O(4), is generalized into multisection (trisection, tetra section, etc.). It is then shown that all symmetries of the N-dimensional anisotropic harmonic oscillator with rational ratios of frequencies (RHO), some of which are underlying the structure of superdeformed and hyperdeformed nuclei, can be obtained from the U(N) symmetry of the corresponding isotropic oscillator with the appropriate combination of multisections. Furthermore, it is seen that bisections of the N-dimensional hydrogen atom, which possesses an O(N+1) symmetry, lead to the U(N) symmetry, so that further multisections of the hydrogen atom lead to the symmetries of the N-dim RHO. The opposite is in general not true, i.e. multisections of U(N) do not lead to O(N+1) symmetries, the only exception being the occurrence of O(4) after the bisection of U(3). Second, it is shown that there is evidence that the recently observed in superdeformed nuclear bands δ I=4 bifurcation is also occurring in normal deformed bands of actinides and rare earths, in hyperdeformed nuclear bands, as well as in rotational bands of diatomic molecules. In addition there is evidence that a δ I=8 bifurcation, of the same order of magnitude as the δ I=4 one, is observed in superdeformed nuclear bands and rotational bands of diatomic molecules. (author)

  17. Major new sources of biological ice nuclei

    Science.gov (United States)

    Moffett, B. F.; Hill, T.; Henderson-Begg, S. K.

    2009-12-01

    Almost all research on biological ice nucleation has focussed on a limited number of bacteria. Here we characterise several major new sources of biogenic ice nuclei. These include mosses, hornworts, liverworts and cyanobacteria. Ice nucleation in the eukaryotic bryophytes appears to be ubiquitous. The temperature at which these organisms nucleate is that at which the difference in vapour pressure over ice and water is at or close to its maximum. At these temperatures (-8 to -18 degrees C) ice will grow at the expense of supercooled water. These organisms are dependent for their water on occult precipitation - fog, dew and cloudwater which by its nature is not collected in conventional rain gauges. Therefore we suggest that these organism produce ice nuclei as a water harvesting mechanism. Since the same mechanism would also drive the Bergeron-Findeisen process, and as moss is known to become airborne, these nuclei may have a role in the initiation of precipitation. The properties of these ice nuclei are very different from the well characterised bacterial nuclei. We will also present DNA sequence data showing that, although related, the proteins responsible are only very distantly related to the classical bacterial ice nuclei.

  18. On search for and synthesis of superdense nuclei

    International Nuclear Information System (INIS)

    The theory of π condensation and the sigma model, predicting the existence of superdense (SD) nuclei, and of the experimental works in the search for such nuclei are presented. Possible properties of SD-nuclei are discussed: the conditions of β-stability and spontaneous fission, the life-time of β-active SD nuclei. The properties of SD nuclei are essentially different from those of ordinary nuclei: the energy of β-decay and the barrier of spontaneous fission are several times higher; the mass defects are significantly different from those of normal nuclei. An experimental search for SD nuclei in natural samples and in products of the interaction of heavy ions and protons with nuclei gave no positive results. In the autors opinion this does not mean the impossibility of the existence of SD-nuclei

  19. Radon dosimetry based on the depth distribution of nuclei in human and rat lungs

    International Nuclear Information System (INIS)

    Calculation of the absorbed dose by different lung cells is necessary for predicting the critical cells that are subject to injury from inhaled Rn and other alpha-particle sources. The absorbed dose was determined for cells in the airways of human and rat lungs, based on airway epithelial thickness and on cell cytoplasm and nuclear volume density as a function of depth from the luminal surface of the airway epithelium. The thickness of the stratified columnar epithelium of human airways varied from 57.8 micron in bronchi to 9.8 microns in bronchioles. The cell populations of all bronchi in human lungs were comparable. The cell populations of trachea and intrapulmonary airways in rats, however, were significantly different. Basal cell populations in rat trachea and human bronchi were similar and formed a nearly continuous layer. In rat bronchi, basal cells were not present in significant numbers. Measurements of epithelial thickness and volume density were used to estimate the absorbed dose for an alpha-particle source (214Po or 218Po) distributed uniformly in the mucus with an equivalent activity of 1 dpm per cm2 of epithelial surface. The following model predictions of dose to human bronchial epithelial cell nuclei for a 218Po alpha-particle source are provided in units of nanogray (nGy) for specific cell types: secretory 158, preciliated 114, ciliated 44, goblet 86, basal 78, and indeterminate cell nuclei 73. The absorbed dose to specific types of rat bronchial epithelial cell nuclei was also predicted: secretory 237, precillated 216, ciliated 203, goblet 204, basal 200, and indeterminate cell nuclei 166 nGy. These and other results indicate that human and rat airway dosimetry have significant differences that may contribute to the differences in cancer cell induction between the two species

  20. Binding energy and stability of heavy and superheavy nuclei

    OpenAIRE

    Kolesnikov, N.N.

    2012-01-01

    Three different ways for description of binding energy of superheavy nuclei are discussed. First, one can consider superheavy nuclei as a part of a whole system of nuclei for which a global mass formula is found. Another way is the detailed local description of energy of superheavy nuclei taking into account the effects of shells and subshells. The third way of description, applied for nuclei in the region limited by principal magic numbers, is attached to the beta-stability line.

  1. Stability and production of superheavy nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Moeller, P. [P. Moller Scientific Computing and Graphics, Inc., Los Alamos, NM (United States)]|[Los Alamos National Lab., NM (United States). Theoretical Div.; Nix, J.R. [Los Alamos National Lab., NM (United States). Theoretical Div.

    1997-12-31

    Beyond uranium heavy elements rapidly become increasingly unstable with respect to spontaneous fission as the proton number Z increases, because of the disruptive effect of the long-range Coulomb force. However, in the region just beyond Z = 100 magic proton and neutron numbers and the associated shell structure enhances nuclear stability sufficient to allow observation of additional nuclei. Some thirty years ago it was speculated that an island of spherical, relatively stable superheavy nuclei would exist near the next doubly magic proton-neutron combination beyond {sup 208}Pb, that is, at proton number Z = 114 and neutron number N = 184. Theory and experiment now show that there also exists a rock of stability in the vicinity of Z = 110 and N = 162 between the actinide region, which previously was the end of the peninsula of known elements, and the predicted island of spherical superheavy nuclei slightly southwest of the magic numbers Z = 114 and N = 184. The authors review here the stability properties of the heavy region of nuclei. Just as the decay properties of nuclei in the heavy region depend strongly on shell structure, this structure also dramatically affects the fusion entrance channel. The six most recently discovered new elements were all formed in cold-fusion reactions. They discuss here the effect of the doubly magic structure of the target in cold-fusion reactions on the fusion barrier and on dissipation.

  2. Ways to fusion of heavy nuclei

    International Nuclear Information System (INIS)

    The experimental synthesis of superheavy elements and heavy nuclei far from the line of stability stimulates the study of the mechanism of fusion in heavy ion collisions at low energies. Two ways could be thought: the first one assumes a fixed mass asymmetry during fusion and describes the process as a melting of two nuclei in the relative distance; the second one describes the evolution of the di-nuclear system to the compound nucleus as a change of the mass asymmetry by nucleon transfer from the light nucleus to the heavy one (dinuclear system concept). With calculated mass parameters and a time-dependent diabatic interaction potential obtained within a two-center shell model, we demonstrate that a structural forbiddingness exists for the motion of the nuclei to smaller internuclear distances in near symmetric dinuclear systems. Energy thresholds for complete fusion in relevant collective variables show that the dinuclear system prefers to proceed in the mass asymmetry degree of freedom to the compound nucleus. The comparison of calculated evaporation residue cross sections with experimental data supports the basic assumption of the dinuclear system concept that the nuclei do not melt together directly, but form the compound nucleus by transferring nucleons in a dinuclear configuration of touching nuclei. (authors)

  3. Superdeformation in Z = 120 superheavy nuclei

    International Nuclear Information System (INIS)

    Significant progress has been made in the discovery of new superheavy nuclei in the last decade. Superheavy nuclei at the extreme end of the periodic table have been synthesized in the laboratory. The stability of nuclei in superheavy mass region came into existence when the extensive shell correction calculations were added to the liquid drop binding energy. As it well known there was no existence of stable nuclides for Z ≥100 by the liquid drop model because of large coulomb repulsion. Various mocroscopic approaches such as non-relativistic density-dependent Skyrme Hartree-Fock (SHF) theory and that of MM type are used extensively to investigate the properties and structure of superheavy nuclei. In spite of impressive agreement with experimental data for the heaviest elements the theoretical uncertainties are large when extrapolating to unknown regions of the nuclear chart. Since in these nuclei the single-particle level density is relatively large, small shifting of single-particle levels can be crucial for determining the shell stability of a nucleus. So there is a need to design the new experiments with exotic radioactive beams to solve the problem of locating the precise island of stability

  4. Fast neutron inelastic scattering from nuclei

    International Nuclear Information System (INIS)

    The need for accurate values of inelastic scattering cross sections appears when the requests for neutron data for reactors and other applied purposes are considered. These requests are partly related to values for spherical nuclei, well studied over many years. These studies were extensively considered in two review papers presented, in 1976, at the International Conference on the Interactions of Neutrons with nuclei. Other requests are related to vibrational and rotational nuclei, and relevant studies have been recently performed. The quality of these investigations and the large number of recent results have lead to concentration on them as the topic of the present review. The constant improvements of the experimental techniques permits precise measurements of inelastic scattering cross sections to the first excited levels over a range of incident energies, such that different reactions mechanisms are predominant in different parts of that range of energies. Quadrupole, hexadecapole and octupole deformation parameters of the target nuclei can be deduced from the data using phenomenological models. The successful application of the analysis over the range of energies leads to the conclusion that reliable information on the shape of the nuclei has been derived. The validity of the various models, which include direct interaction and compound nucleus reaction mechanisms, is discussed in connection with analyses of recent experiments. (author)

  5. Nuclear transfer of porcine embryos using cryopreserved delipated blastomeres as donor nuclei.

    Science.gov (United States)

    Nagashima, H; Ashman, R J; Nottle, M B

    1997-11-01

    Nuclear transfer protocol for the pig using cryopreserved delipated four- to eight-cell and morula stage embryos as nucleus donors was developed. Donor embryos, which had been delipated by micromanipulation following centrifugation for polarizing cytoplasmic lipid droplets, were cryopreserved with 1.5 M 1,2-propanediol and 0.1 M sucrose. Recipient cytoplasts were prepared from ovulated oocytes. Activation of oocytes could be induced more efficiently when electric stimulation was given 53 hr after the hCG injection or later (66-83%), compared with 52 hr or earlier (11-16%, P Membrane fusion rates between donor blastomeres and enucleated oocytes were 88% (127/144) and 97% (56/58, P > 0.05) for the four- to eight-cell and morula stage embryos, respectively. In vitro developmental rates to the two-cell (53/100 vs. 35/65), four-cell (34/100 vs. 26/65), and morula stage (17/100 vs. 18/65) were the same between the nuclear transfer embryos with four- to eight-cell and morula nuclei. However, more embryos reconstituted with morula nuclei developed to blastocysts (15% vs. 6%, P < 0.05). These data demonstrated that blastomeres of cryopreserved, delipated porcine embryos can be used as donor nuclei for nuclear transfer. Frozen-thawed, delipated blastomeres can be efficiently isolated and fused, and therefore provide a useful source of donor nuclei. PMID:9322245

  6. Quantum Monte Carlo calculations of light nuclei

    International Nuclear Information System (INIS)

    Quantum Monte Carlo calculations using realistic two- and three-nucleon interactions are presented for nuclei with up to eight nucleons. We have computed the ground and a few excited states of all such nuclei with Greens function Monte Carlo (GFMC) and all of the experimentally known excited states using variational Monte Carlo (VMC). The GFMC calculations show that for a given Hamiltonian, the VMC calculations of excitation spectra are reliable, but the VMC ground-state energies are significantly above the exact values. We find that the Hamiltonian we are using (which was developed based on 3H, 4He, and nuclear matter calculations) underpredicts the binding energy of p-shell nuclei. However our results for excitation spectra are very good and one can see both shell-model and collective spectra resulting from fundamental many-nucleon calculations. Possible improvements in the three-nucleon potential are also be discussed

  7. Triaxiality in 146,148Sm nuclei

    International Nuclear Information System (INIS)

    Recently, attempts have been made to use the dynamic pairing plus quadrupole model to evaluate B(E2) values, B(E2) branching ratios, and low-lying energy levels for 146,148Sm nuclei, which are in poor agreement with experiment. Application of the boson expansion technique on 148Sm shows too much splitting and an incorrect order for the quintet states, while other properties have not been discussed. In the present work, 146,148Sm nuclei have been described using an asymmetric rotor model framework. The nonaxiality parameter γ has been evaluated using the energy ration E2+'/E6+. Remarkable success has been achieved in explaining the correct ordering of known low-lying energy levels, B(E2) values, and B(E2) branching ratios, which indicate that the so-called spherical nuclei may be treated as triaxial. (author). 8 refs., 9 tabs., 1 fig

  8. Supermassive Black Holes in Galactic Nuclei

    CERN Document Server

    Ho, L C

    1998-01-01

    I review the status of observational determinations of central masses in nearby galactic nuclei. Results from a variety of techniques are summarized, including ground-based and space-based optical spectroscopy, radio VLBI measurements of luminous water vapor masers, and variability monitoring studies of active galactic nuclei. I will also discuss recent X-ray observations that indicate relativistic motions arising from the accretion disks of active nuclei. The existing evidence suggests that supermassive black holes are an integral component of galactic structure, at least in elliptical and bulge-dominated galaxies. The black hole mass appears to be correlated with the mass of the spheroidal component of the host galaxy. This finding may have important implications for many astrophysical issues.

  9. Probing intruder structures in lead nuclei

    International Nuclear Information System (INIS)

    In-beam γ-ray spectroscopy measurements provide important information on coexisting normal and intruder configurations in lead nuclei. However, in these experiments the yrast states are preferentially populated so that in many cases nothing is known about non-yrast states that are essential for obtaining a fuller understanding. Complementary experiments designed to study fine structure in the α decays of polonium nuclei have led to the discovery of low-spin non-yrast states in the daughter lead nuclei, while higher-spin states can be identified through the γ decays of isomeric states. The α-decay studies have the additional benefit of allowing information on configuration mixing in the polonium parents to be deduced from the measured hindrance factors. (orig.)

  10. Probing intruder structures in lead nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Page, R.D. [Dept. of Physics, Oliver Lodge Lab., Univ. of Liverpool, Liverpool (United Kingdom); Ackerman, D.; Andreyev, A.N.; Cagarda, P.; Eskola, K.; Gerl, J.; Greenlees, P.T.; Hessberger, F.P.; Heyde, K.; Hofmann, S.; Huyse, M.; Jones, P.; Joss, D.T.; Julin, R.; Juutinen, S.; Kankaanpaeae, H.; Keenan, A.; Kettunen, H.; Kleinboehl, A.; Kuusiniemi, P.; Lavrentiev, A.; Leino, M.; Matos, M.; Melarangi, A.; Moore, C.J.P.; Muikku, M.; Muenzenberg, G.; Nieminen, P.; O' Leary, C.D.; Rahkila, P.; Reshitko, S.; Schaffner, H.; Schlegel, C.; Scholey, C.; Taylor, M.J.; Uusitalo, J.; Van de Vel, K.; Van Duppen, P.; Weissman, L.; Wheldon, C.; Wyss, R.

    2003-07-01

    In-beam {gamma}-ray spectroscopy measurements provide important information on coexisting normal and intruder configurations in lead nuclei. However, in these experiments the yrast states are preferentially populated so that in many cases nothing is known about non-yrast states that are essential for obtaining a fuller understanding. Complementary experiments designed to study fine structure in the {alpha} decays of polonium nuclei have led to the discovery of low-spin non-yrast states in the daughter lead nuclei, while higher-spin states can be identified through the {gamma} decays of isomeric states. The {alpha}-decay studies have the additional benefit of allowing information on configuration mixing in the polonium parents to be deduced from the measured hindrance factors. (orig.)

  11. Ab Initio Path to Heavy Nuclei

    CERN Document Server

    Binder, Sven; Calci, Angelo; Roth, Robert

    2014-01-01

    We present the first ab initio calculations of nuclear ground states up into the domain of heavy nuclei, spanning the range from 16-O to 132-Sn based on two- plus three-nucleon interactions derived within chiral effective field theory. We employ the similarity renormalization group for preparing the Hamiltonian and use coupled-cluster theory to solve the many-body problem for nuclei with closed sub-shells. Through an analysis of theoretical uncertainties resulting from various truncations in this framework, we identify and eliminate the technical hurdles that previously inhibited the step beyond medium-mass nuclei, allowing for reliable validations of nuclear Hamiltonians in the heavy regime. Following this path we show that chiral Hamiltonians qualitatively reproduce the systematics of nuclear ground-state energies up to the neutron-rich Sn isotopes.

  12. Nucleon localization in light and heavy nuclei

    CERN Document Server

    Zhang, C L; Nazarewicz, W

    2016-01-01

    An electron localization measure was originally introduced to characterize chemical bond structures in molecules. Recently, a nucleon localization based on Hartree-Fock densities has been introduced to investigate $\\alpha$-cluster structures in light nuclei. Compared to the local nucleonic densities, the nucleon localization function has been shown to be an excellent indicator of shell effects and cluster correlations. Using the spatial nucleon localization measure, we investigate the cluster structures in deformed light nuclei and study the emergence of fragments in fissioning heavy nuclei. To illustrate basic concepts of nucleon localization, we employ the deformed harmonic oscillator model. Realistic calculations are carried out using self-consistent nuclear density functional theory with quantified energy density functionals optimized for fission studies. We study particle densities and spatial nucleon localization distributions for deformed cluster configurations of $^{8}$Be and $^{20}$Ne, and also along...

  13. Static quadrupole moments in 120Te nuclei

    International Nuclear Information System (INIS)

    In recent years the region in the vicinity of tin isotopes has been intensively investigated both from experimental and theoretical perspectives. In tellurium nuclei with two protons outside the major shell, the partial level schemes are dominated by the 1g7/2 orbit leading to 6+ isomers in the vicinity of N=82 shell closure. At low spin, the Te nuclei are considered to be one of the best examples of quadrupole vibrators. For any nuclei to be vibrational namely three criteria must be satisfied : (i) the R4/2 ratio is equal to 2, (ii) a nearly degenerate two-phonon triplet of 0+, 2+ and 4+ states (iii) collective electric quadrupole transitions between states differing by one phonon and strong hindrance of E2 transition between states differing by more than one phonon

  14. Acceleration of heavy nuclei in solar flares

    International Nuclear Information System (INIS)

    The overabundance of heavy nuclei in solar cosmic rays of energy approximately less than 5 MeV/nucleon is explained by taking into account the pre-flare ionization states of these nuclei in the region where they are accelerated. A model is proposed which considers two-step accelerations associated with the initial development of solar flares. The first step is closely related to the triggering process of flares, while the second one starts with the development of the explosive phase. Further ionization of medium and heavy nuclei occurs through their interaction with keV electrons accelerated by the first-step acceleration. It is suggested that the role of these electrons is important in producing fully ionized atoms in the acceleration regions. (U.S.)

  15. New approaches to studies of exotic nuclei

    International Nuclear Information System (INIS)

    New generations of 4π gamma-ray detectors, recoil mass spectrometers (RMS), and radioactive beam accelerators will open up many new areas of research, including present inaccessible in-beam and radioactive decay studies of exotic nuclei still farther off stability. The new generation RMS and radioactive beam developments at the Holifield Heavy Ion Research Facility are presented. Current research and further prospects to probe the N -- Z line up to 100Sn are described. Superdeformation in A -- 70 to 190 nuclei is described in terms of its underlying physics of reinforcing proton and neutron shell gaps which lead to new superdeformed, doubly-magic nuclei. Recent results provide new insights into the coexistence of multiple nuclear shapes near the ground states

  16. Superscaling and nucleon momentum distributions in nuclei

    International Nuclear Information System (INIS)

    The scaling functions f(ψ') and F(y) from the ψ'- and y-scaling analyses of inclusive electron scattering from nuclei are constructed within the Coherent Density Fluctuation Model (CDFM) using its two equivalent formulations based on either the local density or the nucleon momentum distribution (NMD). The approach is a natural extension of the relativistic Fermi-gas model to finite realistic nuclear systems. The calculations show that the high-momentum components of NMD in the CDFM and their similarity for different nuclei lead to quantitative description of the super-scaling phenomenon and to a good agreement with the experimental data for y'''- and y-scaling are informative for NMDs at momenta not larger than 2.0-2.5 fm-1. The work shows the role of both basic quantities, the momentum and density distributions, for the explanation of super-scaling in inclusive electron scattering from nuclei

  17. Computer Model Of Fragmentation Of Atomic Nuclei

    Science.gov (United States)

    Wilson, John W.; Townsend, Lawrence W.; Tripathi, Ram K.; Norbury, John W.; KHAN FERDOUS; Badavi, Francis F.

    1995-01-01

    High Charge and Energy Semiempirical Nuclear Fragmentation Model (HZEFRG1) computer program developed to be computationally efficient, user-friendly, physics-based program for generating data bases on fragmentation of atomic nuclei. Data bases generated used in calculations pertaining to such radiation-transport applications as shielding against radiation in outer space, radiation dosimetry in outer space, cancer therapy in laboratories with beams of heavy ions, and simulation studies for designing detectors for experiments in nuclear physics. Provides cross sections for production of individual elements and isotopes in breakups of high-energy heavy ions by combined nuclear and Coulomb fields of interacting nuclei. Written in ANSI FORTRAN 77.

  18. Angular velocity: a new dimension in nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Diamond, R.M.; Stephens, F.S.

    1984-08-09

    Nuclei can be studied from their ground states (approx.O(h/2..pi..)) up to angular momenta of order 100 (h/2..pi..), where they are literally pulled apart by centrifugal effects. This range of angular momenta can be viewed as resulting from cranking the nucleus around a rotation axis, where the critical variable is the cranking velocity. The calculated response of nuclei to such an imposed angular velocity corresponds well with recent observations, and includes a rich and varied interplay of collective and single-particle phenomena.

  19. Governor model for asymmetric deformed nuclei

    International Nuclear Information System (INIS)

    The governor model is extended to include the asymmetric shape of nuclei which allows a simultaneous analysis of the data for both the ground state and the γ-vibrational bands in deformed even-even nuclei. The rotationally invariant core is assumed to be a spheroid with an axis of symmetry parallel to the axis of rotation. The calculations are carried out under the assumption of no stretching. The static γ-deformation results are compared with the VMI(ARM) and Krutov values, and the calculated energies are in good agreement with the experimental data

  20. Dissipation and the population of compound nuclei

    International Nuclear Information System (INIS)

    The importance of nuclear dissipative efforts on the formation of compound nuclei is studied with the γ-ray decay of the giant dipole resonance (GDR) built on highly excited states. The compound nuclei 164Yb, 160Er, and 110Sn were produced with very mass-asymmetric and with more mass-symmetric target/projectile combinations. The large deviation from statistical model prediction observed in the γ-ray spectra from the more symmetrically formed 160Er and 164Yb can be qualitatively explained within the particle exchange model

  1. Theory of the effective interaction in nuclei

    International Nuclear Information System (INIS)

    Extending the coupled-cluster many-body method the authors present ab initio calculations of the effective interaction in nuclei neighbouring 16O. The convergence problems encountered in previous approaches are overcome by means of three-body Bethe-Faddeev summations included fully self-consistently. The results for mass 15 to 18 nuclei are in agreement with experiment to within the uncertainties due to insufficient knowledge of the bare nucleon-nucleon interaction and neglect of mesonic and isobaric degrees of freedom. (Auth.)

  2. Doubly magic properties in superheavy nuclei

    Institute of Scientific and Technical Information of China (English)

    HUANG Ya-Wei; ZHU Jian-Yu

    2009-01-01

    A systematic study of global properties of superheavy nuclei in the framework of the Liquid Drop Model and the Strutinsky shell correction method is performed. The evolution equilibrium deformations, TRS graphs and α-decay energies are calculated using the TRS model. The analysis covers a wide range of even-even superheavy nuclei from Z = 102 to 122. Magic numbers and their observable influence occurring in this region have been investigated. Shell closures appear at proton number Z = 114 and at neutron number N = 184.

  3. Structure of neutron-rich nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Nazarewicz, W. [Univ. of Tennessee, Knoxville, TN (United States). Dept. of Physics]|[Oak Ridge National Lab., TN (United States). Physics Div.]|[Warsaw Univ. (Poland). Inst. of Theoretical Physics

    1997-11-01

    One of the frontiers of today`s nuclear science is the ``journey to the limits``: of atomic charge and nuclear mass, of neutron-to-proton ratio, and of angular momentum. The new data on exotic nuclei are expected to bring qualitatively new information about the fundamental properties of the nucleonic many-body system, the nature of the nuclear interaction, and nucleonic correlations at various energy-distance scales. In this talk, current developments in nuclear structure of neutron-rich nuclei are discussed from a theoretical perspective.

  4. Medium energy hadron scattering from nuclei

    International Nuclear Information System (INIS)

    The Glauber approximation for medium energy scattering of hadronic projectiles from nuclei is combined with the interacting boson model of nuclei to produce a transition matrix for elastic and inelastic scattering in algebraic form which includes coupling to all the intermediate states. We present closed form analytic expresions for the transition matrix elements for the three dynamical symmetries of the interacting boson model; that is for, a spherical quadrupole vibrator, a γ unstable rotor, and both prolate and oblate axially symmetric rotors. We give examples of application of this formalism to proton scattering from 154Sm and 154Gd. 27 refs., 5 figs., 1 tab

  5. Light nuclei from chiral EFT interactions

    International Nuclear Information System (INIS)

    Recent developments in nuclear theory allow us to make a connection between quantum chromodynamics (QCD) and low-energy nuclear physics. First, chiral effective field theory (XEFT) provides a natural hierarchy to define two-nucleon (NN), three-nucleon (NNN), and even four-nucleon interactions. Second, ab-initio methods have been developed capable to test these interactions for light nuclei. In this contribution, we discuss ab-initio no-core shell-model (NCSM) calculations for s-shell and p-shell nuclei with NN and NNN interactions derived within XEFT. Presented at the 20th Few-Body Conference, Pisa, Italy, 10-14 September 2007. (author)

  6. Adiabatic fission barriers in superheavy nuclei

    OpenAIRE

    Jachimowicz, P.; Kowal, M; Skalski, J.

    2016-01-01

    Using the microscopic-macroscopic model based on the deformed Woods-Saxon single-particle potential and the Yukawa-plus-exponential macroscopic energy we calculated static fission barriers $B_{f}$ for 1305 heavy and superheavy nuclei $98\\leq Z \\leq 126$, including even - even, odd - even, even - odd and odd - odd systems. For odd and odd-odd nuclei, adiabatic potential energy surfaces were calculated by a minimization over configurations with one blocked neutron or/and proton on a level from ...

  7. Statistical properties of quantum spectra in nuclei

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Some aspects of quantum chaos in a finite system have been studied based on the analysis of statistical behavior of quantum spectra in nuclei.The experiment data show the transition from order to chaos with increasing excitation energy in spherical nuclei.The dependence of the order to chaos transition on nuclear deformation and nuclear rotating is described.The influence of pairing effect on the order to chaos transition is also discussed.Some important experiment phenomena in nuclear physics have been understood from the point of view of the interplay between order and chaos.

  8. Pairing schemes for HFB calculations of nuclei

    CERN Document Server

    Duguet, T; Bonche, P

    2005-01-01

    Several pairing schemes currently used to describe superfluid nuclei through Hartree-Fock-Bogolyubov (HFB) calculations are briefly reviewed. We put a particular emphasis on the regularization recipes used in connection with zero-range forces and on the density dependence which usually complement their definition. Regarding the chosen regularization process, the goal is not only to identify the impact it may or may not have on pairing properties of nuclei through spherical 1D HFB calculations but also to assess its tractability for systematic axial 2D and 3D mean-field and beyond-mean-field calculations.

  9. Reflections on cavitation nuclei in water

    DEFF Research Database (Denmark)

    Mørch, Knud Aage

    2007-01-01

    The origin of cavitation bubbles, cavitation nuclei, has been a subject of debate since the early years of cavitation research. This paper presents an analysis of a representative selection of experimental investigations of cavitation inception and the tensile strength of water. At atmospheric...... on the surface of particles and bounding walls. Such nuclei can be related to the full range of tensile strengths measured, when differences of experimental conditions are taken into consideration. The absence or presence of contamination on surfaces, as well as the structure of the surfaces, are...

  10. Actin polymerisation at the cytoplasmic face of eukaryotic nuclei

    Directory of Open Access Journals (Sweden)

    David-Watine Brigitte

    2006-05-01

    Full Text Available Abstract Background There exists abundant molecular and ultra-structural evidence to suggest that cytoplasmic actin can physically interact with the nuclear envelope (NE membrane system. However, this interaction has yet to be characterised in living interphase cells. Results Using a fluorescent conjugate of the actin binding drug cytochalasin D (CD-BODIPY we provide evidence that polymerising actin accumulates in vicinity to the NE. In addition, both transiently expressed fluorescent actin and cytoplasmic micro-injection of fluorescent actin resulted in accumulation of actin at the NE-membrane. Consistent with the idea that the cytoplasmic phase of NE-membranes can support this novel pool of perinuclear actin polymerisation we show that isolated, intact, differentiated primary hepatocyte nuclei support actin polymerisation in vitro. Further this phenomenon was inhibited by treatments hindering steric access to outer-nuclear-membrane proteins (e.g. wheat germ agglutinin, anti-nesprin and anti-nucleoporin antibodies. Conclusion We conclude that actin polymerisation occurs around interphase nuclei of living cells at the cytoplasmic phase of NE-membranes.

  11. Embryonic effects transmitted by male mice irradiated with 512 MeV/u 56Fe nuclei

    International Nuclear Information System (INIS)

    High-energy, high-charge nuclei may contribute substantially to the yearly equivalent dose in space flight from galactic cosmic radiation (GCR) at solar minimum. The largest single heavy-ion component is 56Fe. We used the mouse embryo chimera assay to test 512 MeV/u 56Fe nuclei for effects on the rate of proliferation of embryonic cells transmitted by sperm from irradiated mice. Male CD1 mice were acutely irradiated with 0.01, 0.05, or 0.1 Gy (LET, 184 keV/μm; fluence, 3.5 x 104-3.3 x 105 nuclei/cm2; average dose rate, 0.02 Gy/min) at the Lawrence Berkeley Laboratory BEVATRON/BEVALAC Facility in Berkeley, CA. Irradiated males were bred weekly for 7 weeks to nonirradiated females and their four-cell embryos were paired with control embryos, forming aggregation chimeras. After 30-35 h of culture, chimeras were dissociated to obtain open-quotes proliferation ratiosclose quotes (number of cells contributed by the embryo from the irradiated male/total number of cells in the chimera). Significant dose-dependent decreases in proliferation ratios were obtained across all three dose groups for postirradiation week 2 (P 56Fe nuclei. However, up to 47% of sperm during postirradiation weeks 1 and 2 transmitted proliferation ratios that were at or below one standard deviation from control mean proliferation ratios. 26 refs., 4 figs., 10 tabs

  12. Measurement of apoptosis by SCAN©, a system for counting and analysis of fluorescently labelled nuclei

    Directory of Open Access Journals (Sweden)

    Neta Shlezinger

    2014-11-01

    Full Text Available Apoptosis-like programmed cell death (A-PCD is a universal process common to all types of eukaryotic organisms. Because A-PCD-associated processes are conserved, it is possible to define A-PCD by a standard set of markers. Many of the popular methods to measure A-PCD make use of fluorescent ligands that change in intensity or cellular localization during A-PCD. In single cell organisms, it is possible to quantify levels of A-PCD by scoring the number of apoptotic cells using flow cytometry instruments. In a multicellular organism, quantification of A-PCD is more problematic due to the complex nature of the tissue. The situation is further complicated in filamentous fungi, in which nuclei are divided between compartments, each containing a number of nuclei, which can also migrate between the compartments. We developed SCAN©, a System for Counting and Analysis of Nuclei, and used it to measure A-PCD according to two markers – chromatin condensation and DNA strand breaks. The package includes three modules designed for counting the number of nuclei in multi-nucleated domains, scoring the relative number of nuclei with condensed chromatin, and calculating the relative number of nuclei with DNA strand breaks. The method provides equal or better results compared with manual counting, the analysis is fast and can be applied on large data sets. While we demonstrated the utility of the software for measurement of A-PCD in fungi, the method is readily adopted for measurement of A-PCD in other types of multicellular specimens.

  13. Plant nuclei can contain extensive grooves and invaginations

    Science.gov (United States)

    Collings, D. A.; Carter, C. N.; Rink, J. C.; Scott, A. C.; Wyatt, S. E.; Allen, N. S.; Brown, C. S. (Principal Investigator)

    2000-01-01

    Plant cells can exhibit highly complex nuclear organization. Through dye-labeling experiments in untransformed onion epidermal and tobacco culture cells and through the expression of green fluorescent protein targeted to either the nucleus or the lumen of the endoplasmic reticulum/nuclear envelope in these cells, we have visualized deep grooves and invaginations into the large nuclei of these cells. In onion, these structures, which are similar to invaginations seen in some animal cells, form tubular or planelike infoldings of the nuclear envelope. Both grooves and invaginations are stable structures, and both have cytoplasmic cores containing actin bundles that can support cytoplasmic streaming. In dividing tobacco cells, invaginations seem to form during cell division, possibly from strands of the endoplasmic reticulum trapped in the reforming nucleus. The substantial increase in nuclear surface area resulting from these grooves and invaginations, their apparent preference for association with nucleoli, and the presence in them of actin bundles that support vesicle motility suggest that the structures might function both in mRNA export from the nucleus and in protein import from the cytoplasm to the nucleus.

  14. Formation and decay of hot nuclei

    International Nuclear Information System (INIS)

    The challenge in understanding the behaviour of hot nuclei is twofold: how are they formed in nucleus-nucleus collisions and how do they decay. Both aspects are considered in the light of theories developed recently and experimental data. Special emphasis has been put on the relevance of temperature measurements as well as on the concept of a limiting temperature

  15. Contact nuclei formation in aqueous dextrose solutions

    Science.gov (United States)

    Cerreta, Michael K.; Berglund, Kris A.

    1990-06-01

    A laser Raman microprobe was used in situ to observe the growth of alpha dextrose monohydrate on alpha anhydrous dextrose crystals. The Raman spectra indicate growth of the monohydrate below 28.1°C, but the presence of only the anhydrous form above 40.5°C. Contact nucleation experiments with parent anhydrous crystals yielded only monohydrate nuclei below 28.1°C, while contacts in solutions between 34.5 and 41.0°C produced both crystalline forms, and contacts in solutions above 43.5°C produced only anhydrous nuclei. The inability of the monohydrate to grow on anhydrous crystals in the same solution that forms the two crystalline phases with a single contact precludes a simple attrition mechanism of nuclei formation. For the same reason, the hypothetical mechanism involving parent crystal stabilization of pre-crystalline clusters, allowing the clusters to grow into nuclei, is also contradicted. A third, mechanism, which may be a combination of the two, is believed to apply.

  16. Two-phase model of rotating nuclei

    International Nuclear Information System (INIS)

    Using the generator-coordinate method a model is formulated in which the nucleus is treated as a triaxial rotator with coupled normal and superconductive phases. Averaging the model hamiltonian over coherent states the effects of different orientations of the mass quadrupoloid with respect to the angular momentum are studied in the case of 156166Er nuclei. (Auth.)

  17. Two-phase model of rotating nuclei

    International Nuclear Information System (INIS)

    Using the generator-coordinate method the model is formulated in which the nucleus is treated as a triaxial rotator with coupled normal and superconductive phases. Averaging the model Hamiltonian over coherent states the effects of different orientations of the mass quadrupoloid with respect to the angular momentum are studied in the case of 156Er and 166Er nuclei. (author)

  18. Nucleon momentum and density distributions of nuclei

    International Nuclear Information System (INIS)

    In the framework of recently suggested density coherent fluctuations model the nucleon momentum and density distributions are examined. Nucleon momentum and density distributions are expressed in terms of the fluctuation's function, experimentally obtainable from the elastic electron-nuclei scattering. (author)

  19. Heavy Mesons in Nuclear Matter and Nuclei

    CERN Document Server

    Tolos, Laura; Garcia-Recio, Carmen; Molina, Raquel; Nieves, Juan; Oset, Eulogio; Ramos, Angels; Romanets, Olena; Salcedo, Lorenzo Luis; Torres-Rincon, Juan M

    2014-01-01

    Heavy mesons in nuclear matter and nuclei are analyzed within different frameworks, paying a special attention to unitarized coupled-channel approaches. Possible experimental signatures of the properties of these mesons in matter are addressed, in particular in connection with the future FAIR facility at GSI.

  20. Heavy Mesons in Nuclear Matter and Nuclei

    International Nuclear Information System (INIS)

    Heavy mesons in nuclear matter and nuclei are analyzed within different frameworks, paying a special attention to unitarized coupled-channel approaches. Possible experimental signatures of the properties of these mesons in matter are addressed, in particular in connection with the future FAIR facility at GSI

  1. Photodisintegration of p-process nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Wagner, A.; Nair, C.; Erhard, M.; Bemmerer, D.; Beyer, R.; Junghans, A.; Kosev, K.; Rusev, G.; Schilling, K.D.; Schwengner, R. [Forschungszentrum Dresden-Rossendorf, 01314 Dresden (Germany); Grosse, E. [Forschungszentrum Dresden-Rossendorf, 01314 Dresden (Germany); Technische Universitaet Dresden, 01062 Dresden (Germany)

    2009-07-01

    The neutron deficient p-nuclei are shielded from the s- or r-process by stable isotopes. P-nuclei are likely to be formed in high temperature cosmic scenarios like exploding supernovae by photodisintegration reactions on heavy r- or s- seed nuclei. The lack of experimental information on energy-dependent cross sections especially for ({gamma},p) and ({gamma},{alpha}) reactions reduces the applicability of nucleosynthesis models. Using intense bremsstrahlung produced at the superconducting electron linear accelerator ELBE at Forschungszentrum Dresden-Rossendorf we investigated ({gamma},n), ({gamma},p) and ({gamma},{alpha}) reactions for the medium-mass p-nuclei {sup 92}Mo and {sup 144}Sm, as well as ({gamma},n) reactions for {sup 100}Mo and {sup 154}Sm by photo-activation. The lowest photoactivation yields have been measured in an underground laboratory. The photodisintegration of {sup 197}Au serves as a benchmark and it is compared to data measured previously with the positron annihilation technique.

  2. Mass measurements of exotic nuclei with speg

    International Nuclear Information System (INIS)

    Masses of up to know unknown nuclei have been obtained in the present experiment with a total of 13 hours of beam for accumulation of data. Masses of 20N, 21N, 23O, 24F, 25F and 26F are given and compared to predictions from other references

  3. Closed shells at drip-line nuclei

    OpenAIRE

    Dobaczewski, J.; Nazarewicz, W.; Werner, T. R.

    1994-01-01

    The shell structure of magic nuclei far from stability is discussed in terms of the self-consistent spherical Hartree-Fock-Bogoliubov theory. In particular, the sensitivity of the shell-gap sizes and the two-neutron separation energies to the choice of particle-hole and particle-particle components of the effective interaction is investigated.

  4. Standard Model Masses and Models of Nuclei

    OpenAIRE

    Rivero, Alejandro

    2003-01-01

    We note an intriguing coincidence in nuclear levels, that the subshells responsible for doubly magic numbers happen to bracket nuclei at the energies of the Standard Model bosons. This could show that these bosons actually contribute to the effective mesons of nuclear models.

  5. Energy Density Functional Approach to Superfluid Nuclei

    OpenAIRE

    Yu, Yongle; Bulgac, Aurel

    2002-01-01

    We show that within the framework of a simple local nuclear energy density functional (EDF), one can describe accurately the one-- and two--nucleon separation energies of semi--magic nuclei. While for the normal part of the EDF we use previously suggested parameterizations, for the superfluid part of the EDF we use the simplest possible local form compatible with known nuclear symmetries.

  6. Coherent dissociation of relativistic 12N nuclei

    International Nuclear Information System (INIS)

    The dissociation of relativistic 12N nuclei having a momentum of 2 GeV/c per nucleon and undergoing the most peripheral interactions in a track emulsion is studied. The picture of charged topology of product ensembles of relativistic fragments and special features of their angular distributions are presented

  7. Alpha-particle condensation in nuclei

    International Nuclear Information System (INIS)

    A round up of the present status of the conjecture that nα nuclei form an α-particle condensate in excited states close to the nα threshold is given. Experiments which could demonstrate the condensate character are proposed. Possible lines of further theoretical developments are discussed. (authors)

  8. Alpha-particle condensation in nuclei

    International Nuclear Information System (INIS)

    A round-up of the present status of the conjecture that nα nuclei form an α-particle condensate in excited states close to the nα threshold is given. Experiments which could demonstrate the condensate character are proposed. Possible lines of further theoretical developments are discussed. (author)

  9. Spectroscopic Studies of Exotic Nuclei at ISOLDE

    CERN Multimedia

    2002-01-01

    Experiment IS50 is designed to: a) Investigate the full range of the @b strength function of heavy (A~$>$~48)~K nuclei b)~Study the decay of isomeric states in n-deficient bromine nuclei (A~=~72 and 70). The heavy K isotopes appeared to have complex decay schemes, including feeding by the @b-decay of levels having open neutron channels (Beta decay energy Q(@b) exceeds neutron binding energy S^n); in addition, a large fraction of the delayed transitions populate excited levels in the daughter nuclei. The allowed @b-decay selects states in the daughter nucleus with wave functions having a large overlap with the initial state. Hence, the @b strength functions, deduced from these deca reveal simple structures correlated to the particle-hole excitation energies in the Ca nuclei. These results are valuable for the application of the shell-model calculations far from stability. The delayed neutron spectra are measured with a large area curved scintillator in coincidence either with high resolution Ge(Li) detectors, ...

  10. Physics of the continuum of borromean nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Vaagen, J.S.; Rogde, T. [Dept. of Physics, Univ. of Bergen (Norway); Danilin, B.V. [RRC The Kurchatov Inst., Kurchatov, Moscow (Russian Federation); Ershov, S.N. [JINR, Dubna, Moscow (Russian Federation); Thompson, I.J. [Dept. of Physics, Univ. of Surrey, Guildford (United Kingdom); Zhukov, M.V. [Chalmers Univ. of Technology and Goeteborg Univ., Goeteborg (Sweden); RNBT Collaboration

    1998-06-01

    The continuum states of two-neutron halo nuclei are calculated in the method of hyperspherical harmonics. Using DWIA theory appropriate for dilute halo matter we have probed the structure of the low-lying {sup 6}He continuum via calculations of charge-exchange and inelastic scattering. (orig.)

  11. Nuclear mass systematics and exotic nuclei

    International Nuclear Information System (INIS)

    The importance of theoretical studies of nuclei for stability in checking and improving mass formulae is discussed. Several tests for existing mass formulae or systematics are considered. It is believed that most of the shortcomings found are due to shell effects not included in the formulae

  12. Four-body correlations in nuclei

    CERN Document Server

    Sambataro, M

    2015-01-01

    Low-energy spectra of 4$n$ nuclei are described with high accuracy in terms of four-body correlated structures ("quartets"). The states of all $N\\geq Z$ nuclei belonging to the $A=24$ isobaric chain are represented as a superposition of two-quartet states, with quartets being characterized by isospin $T$ and angular momentum $J$. These quartets are assumed to be those describing the lowest states in $^{20}$Ne ($T_z$=0), $^{20}$F ($T_z$=1) and $^{20}$O ($T_z$=2). We find that the spectrum of the self-conjugate nucleus $^{24}$Mg can be well reproduced in terms of $T$=0 quartets only and that, among these, the $J$=0 quartet plays by far the leading role in the structure of the ground state. The same conclusion is drawn in the case of the three-quartet $N=Z$ nucleus $^{28}$Si. As an application of the quartet formalism to nuclei not confined to the $sd$ shell, we provide a description of the low-lying spectrum of the proton-rich $^{92}$Pd. The results achieved indicate that, in 4$n$ nuclei, four-body degrees of f...

  13. Statistical properties of hot zirconium nuclei

    International Nuclear Information System (INIS)

    The statistical properties and stability of hot nuclei have been studied, using Hartree-Fock calculations and the temperature dependence of these properties has been investigated. In this work, the statistical theory was used to extract the properties of Zr isotopes

  14. Abdominal surgery activates nesfatin-1 immunoreactive brain nuclei in rats.

    Science.gov (United States)

    Stengel, Andreas; Goebel, Miriam; Wang, Lixin; Taché, Yvette

    2010-02-01

    Abdominal surgery-induced postoperative gastric ileus is well established to induce Fos expression in specific brain nuclei in rats within 2-h after surgery. However, the phenotype of activated neurons has not been thoroughly characterized. Nesfatin-1 was recently discovered in the rat hypothalamus as a new anorexigenic peptide that also inhibits gastric emptying and is widely distributed in rat brain autonomic nuclei suggesting an involvement in stress responses. Therefore, we investigated whether abdominal surgery activates nesfatin-1-immunoreactive (ir) neurons in the rat brain. Two hours after abdominal surgery with cecal palpation under short isoflurane anesthesia or anesthesia alone, rats were transcardially perfused and brains processed for double immunohistochemical labeling of Fos and nesfatin-1. Abdominal surgery, compared to anesthesia alone, induced Fos expression in neurons of the supraoptic nucleus (SON), paraventricular nucleus (PVN), locus coeruleus (LC), Edinger-Westphal nucleus (EW), rostral raphe pallidus (rRPa), nucleus of the solitary tract (NTS) and ventrolateral medulla (VLM). Double Fos/nesfatin-1 labeling showed that of the activated cells, 99% were nesfatin-1-immunoreactive in the SON, 91% in the LC, 82% in the rRPa, 74% in the EW and VLM, 71% in the anterior parvicellular PVN, 47% in the lateral magnocellular PVN, 41% in the medial magnocellular PVN, 14% in the NTS and 9% in the medial parvicellular PVN. These data established nesfatin-1 immunoreactive neurons in specific nuclei of the hypothalamus and brainstem as part of the neuronal response to abdominal surgery and suggest a possible implication of nesfatin-1 in the alterations of food intake and gastric transit associated with such a stressor. PMID:19944727

  15. Nuclear Shell Structure and Beta Decay I. Odd A Nuclei II. Even A Nuclei

    Science.gov (United States)

    Mayer, M.G.; Moszkowski, S.A.; Nordheim, L.W.

    1951-05-01

    In Part I a systematics is given of all transitions for odd A nuclei for which sufficiently reliable data are available. The allowed or forbidden characters of the transitions are correlated with the positions of the initial and final odd nucleon groups in the nuclear shell scheme. The nuclear shells show definite characteristics with respect to parity of the ground states. The latter is the same as the one obtained from known spins and magnetic moments in a one-particle interpretation. In Part II a systematics of the beta transitions of even-A nuclei is given. An interpretation of the character of the transitions in terms of nuclear shell structure is achieved on the hypothesis that the odd nucleon groups have the same structure as in odd-A nuclei, together with a simple coupling rule between the neutron and proton groups in odd-odd nuclei.

  16. Shell structure evolution in nuclei: new paradigm

    International Nuclear Information System (INIS)

    Shell structure evolution in nuclei situated at the extremes of neutron and proton excess are investigated using in-beam gamma spectroscopy techniques with radioactive beams at GANIL. A selection of results obtained very recently is presented: i) The reduced transition probabilities B(E2;01+ → 2+) of the neutron-rich 74Zn and 70Ni nuclei have been measured using Coulomb excitation at intermediate energy. An unexpected large proton core polarization has been found in 70Ni and interpreted as being due to the monopole interaction between the neutron g9/2 and protons f7/2 and f5/2 spin-orbit partner orbitals. ii) Two proton knock-out reactions has been performed in order to study the most neutron-rich nuclei at the N=28 shell closure. Gamma rays spectra and momentum distribution have been obtained for 42Si and neighboring nuclei. Evidences has been found for a deformed structure for 42Si and for the disappearance of the spherical N=28 shell effect. iii) The in-beam gamma spectroscopy of 36Ca performed using neutron knock-out reactions revealed that N=16 is as large sub-shell closure as large as Z=16 in 36S. The uniquely large excitation energy difference of the first 2+ state in these mirror nuclei turns out to be a consequence of the relatively pure neutron (in 36Ca) or proton (in 36S) 1p(d3/2)-1h(s1/2) nature. (author)

  17. Spectroscopic factors for two-proton radioactive nuclei

    Indian Academy of Sciences (India)

    Chinmay Basu

    2004-11-01

    Spectroscopic factors for two-proton emitting nuclei are discussed in the framework of the BCS (Bardeen–Cooper–Schriefer) model. Calculations carried out for the two-proton unstable 45Fe, 48Ni and 54Zn nuclei are presented.

  18. PPCO: polarizational-polarizational correlation from oriented nuclei

    International Nuclear Information System (INIS)

    A Polarizational-Polarizational Correlation from Oriented Nuclei (PPCO) measuring method is described. The method allows one to determine spin and parity of the excited states of nuclei as well as multipole gamma transitions

  19. Level density parameter for nuclei with few nucleons above magic number nuclei Z = 82

    International Nuclear Information System (INIS)

    Since nuclei with extreme neutron richness formed in collisions, or otherwise, or obtained as fission fragments, may be in an excited state, they require a thermodynamical approach in which both the spin degree of freedom and temperature effects have been incorporated. This is similar to the earlier works where these effects have been incorporated to reproduce microscopic fluctuations in high spin nuclei. This spin degree of freedom inherently involves deformation and structural or shape changes

  20. Saturable triiodothyronine-binding sites in the pituitary nuclei of salmonid teleost fish

    International Nuclear Information System (INIS)

    High-affinity, limited-capacity, 3,5,3'-triiodo-L-thyronine (T3)-binding sites were established by in vitro saturation analysis in cell nuclei of the pituitary gland of arctic charr. The sites were extracted from the purified nuclei using 0.4 M NaCl and incubated with [125I]T3 in the presence of 0.2 M NaCl. T3 saturable binding attained equilibrium after 18-24 hr of incubation at 4 degrees. The association constant ranged from 6.7 to 20.1 liters.mol-1 x 10(9), indicating a T3 affinity greater than that for T3-binding sites in rainbow trout liver. The maximal binding capacity ranged from 0.93 to 2.05 10(-13) mol.mg DNA-1, representing a mean site abundance corresponding to 60% of that for nuclei from trout liver. Thyroxine (T4) completely displaced [125I]T3 in the pituitary nuclei of arctic charr and T3 completely displaced [125I]T4 in the pituitary nuclei of rainbow trout, suggesting that in salmonids both T4 and T3 bind to the same single class of sites. However, the site affinity for T4 was approximately 20-50x less than that for T3. The possible roles of these sites in pituitary function as well as their relationship to other nuclear T3-binding sites in salmonid fish are discussed

  1. Detection of high-grade atypia nuclei in breast cancer imaging

    Science.gov (United States)

    Noël, Henri; Roux, Ludovic; Lu, Shijian; Boudier, Thomas

    2015-03-01

    Along with mitotic count, nuclear pleomorphism or nuclear atypia is an important criterion for the grading of breast cancer in histopathology. Though some works have been done in mitosis detection (ICPR 2012,1 MICCAI 2013,2 and ICPR 2014), not much work has been dedicated to automated nuclear atypia grading, especially the most difficult task of detection of grade 3 nuclei. We propose the use of Convolutional Neural Networks for the automated detection of cell nuclei, using images from the three grades of breast cancer for training. The images were obtained from ICPR contests. Additional manual annotation was performed to classify pixels into five classes: stroma, nuclei, lymphocytes, mitosis and fat. At total of 3,000 thumbnail images of 101 × 101 pixels were used for training. By dividing this training set in an 80/20 ratio we could obtain good training results (around 90%). We tested our CNN on images of the three grades which were not in the training set. High grades nuclei were correctly classified. We then thresholded the classification map and performed basic analysis to keep only rounded objects. Our results show that mostly all atypical nuclei were correctly detected.

  2. 大鼠脾虚证与血清甲状腺激素及下丘脑、胸腺细胞核T3受体关系%RELATIONSHIP BETWEEN SPLEEN-ASTHENIA SYNDROME AND SERUM THYROXIN,T3 RECEPTORS OF HYPOTHALAMUS CELLS & THYMUS T LYMPHOCYTE NUCLEI IN RATS

    Institute of Scientific and Technical Information of China (English)

    李刚; 夏天; 王宗仁; 张仲海

    2001-01-01

    目的:探讨脾虚证与血清甲状腺激素及下丘脑、胸腺细胞核T3受体的关系。方法:成年SD大鼠32只随机分为4组(每组8只):A组(正常组)、B组(脾虚组)、C组(治疗组)、D组(自复组)。采用放射配基分析法,测定各组大鼠血清T3、T4、FT3、FT4、γ-T3及下丘脑、胸腺细胞核T3受体的含量。结果:B、D组大鼠血清T3、T4、FT3、FT4含量均较A、C组低,有显著差异(P<0.05或P<0.01);各组间血清γ-T3含量无显著性差异;B、D组下丘脑、胸腺细胞核T3受体含量较A、C组低,有显著差异P<0.01)。结论:血清甲状腺激素及下丘脑、胸腺细胞核T3受体的水平降低,可导致甲状腺激素生物效应低下,经由神经内分泌免疫调节环路,削弱免疫功能,这可能是脾虚证的一种重要病机。%Objective:To study the relationship between Spleen-asthenia syndrome and serum thyroxin,T3 receptors of hypothalamus cells & thymus T lymphocyte nuclei in rats.Method:Rhubarb decoction was used to develop spleen-asthenia syndrome in SD adult rat.32 rats were averagely divided into four groups at random:Group A(control group),group B(spleen-asthenia group),group C(group treated with Sijunzi decoction),group D(spontaneous rehabilitation group).The radioimmunoassay was applied to measure serum thyroxin levels and the contents of T3 receptors of hypothalamus cells and thymus T lymphocyte nuclei of every rat.Result:The serum levels of T3,T4,FT3,FT4,the contents of T3 receptors of hypothalamus cells and thymus T lymphocyte nuclei in group B,D were lower than those in group A,C.The difference between them was significant.Serum level of γ-T3 in four groups had no significant difference.Conclusion:The decline of T3,T4,FT3,FT4 serum levels,and the contents of nuclear T3 receptors in hypothalamus cells & thymus T lymphocytes can influence the activity of thyroxin,then the immunity function will be impaired via

  3. Sturmian method for light exotic nuclei

    International Nuclear Information System (INIS)

    This research concentrates on halo like systems: Abnormally large light nuclei at the neutron dripline which exhibit a clear separation between a ''normal'' core nucleus and a loosely bound low-density veil of neutrons. This phenomenon offers very interesting possibilities for studies of neutron matter under extreme conditions in a low-density background. This work is focused on few-body theory for light halo-like nuclei: Borromean systems, i.e. while the three-body-like system is bound (but very loosely) none of the binary subsystems are bound. Three representatives were closely investigated: 6He. 11Li and 14Be. The aim of this work was to gain an insight how important are for light exotic nuclei different aspects of three-body description. The investigation was performed by applying for light halo systems a few-body model originally developed for ordinary heavy well-bound nuclei. Special features of the Borromean systems, most important of which are enormous size and weak binding, suggested the need for modifications of the method to allow more subtle treatment. Theoretical considerations and numerical tests provided evidences for importance to accurately include certain effects into the description scheme. Our calculations are based on Bisturmian three-body method. The two-particle (three body) bound state is expanded on a set of Sturm-Liouville basis functions. These basis functions are derived from a well-depth-prescription method where single-particle wave functions are used which are eigenstates in a Saxon-Woods potential with one-nucleon separation energy ε each. The basis set is in principle infinite, but discrete, and corresponds to the intuitive picture of increasingly deeper wells, all able to support bound motion with energy ε. The three-body bound state is found by diagonalising with the neutron-core and neutron-neutron potentials simultaneously. Pauli blocking is taken into account by projecting out those basis states coinciding with occupied

  4. Shell evolution of atomic nuclei due to the tensor force

    International Nuclear Information System (INIS)

    Magic numbers and shell structure are extremely important for the study of atomic nuclei, as they determine the mass, the shape of surface, and the limit of the existence of nuclei, and have been considered to be universal over all nuclei, since Mayer and Jensen (1949). However, recent studies on exotic nuclei with large variations of proton or neutron numbers indicate that the changes of magic numbers and shell structure, i.e, shell evolution, arise due to nuclear forces, in particular the tensor force, demolishing this universality. We shall present an overview of such a paradigm shift emerging in exotic nuclei. (author)

  5. Giant dipole resonance in highly excited nuclei

    CERN Document Server

    Dang, Nguyen Dinh

    2013-01-01

    The evolution of the giant dipole resonance's (GDR) width and shape at finite temperature $T$ and angular momentum $J$ is described within the framework of the phonon damping model (PDM). The PDM description is compared with the established experimental systematics obtained from heavy-ion fusion and inelastic scattering of light particles on heavy target nuclei, as well as with predictions by other theoretical approaches. Extended to include the effect of angular momentum $J$, its strength functions have been averaged over the probability distributions of $T$ and $J$ for the heavy-ion fusion-evaporation reaction, which forms the compound nucleus $^{88}$Mo at high $T$ and $J$. The results of theoretical predictions are found in excellent agreement with the experimental data. The predictions by PDM and the heavy-ion fusion data are also employed to predict the viscosity of hot medium and heavy nuclei.

  6. Heavy Nuclei Photofission at Intermediate Energies

    CERN Document Server

    Deppman, A; Guimaraes, V; Demekhina, N A; Karapetyan, G S

    2013-01-01

    In the present work the yields of fission fragments, from Bremsstrahlung induced fission of 232Th, 238U targets, were reproduced by CRISP model calculations, to which a multimodal fission option had been added. An extension of the calculation to the properties of the fission products is presented. Dividing the fissioning nuclei according to their fissionability, an approach which accounts for the contribution of symmetric and asymmetric fission is introduced. It allows to calculate the main parameters of the fission fragment charge distribution: the most probable charge for a given fission product mass chain and the width parameter. Furthermore, it reproduces the features of fragment mass distribution, and evaluates the fissility of fissioning nuclei in photon-induced fission. A comparison between the results of this calculation and experimental data is accomplished.

  7. Antiproton Induced Fission and Fragmentation of Nuclei

    CERN Multimedia

    2002-01-01

    The annihilation of slow antiprotons with nuclei results in a large highly localized energy deposition primarily on the nuclear surface. \\\\ \\\\ The study of antiproton induced fission and fragmentation processes is expected to yield new information on special nuclear matter states, unexplored fission modes, multifragmentation of nuclei, and intranuclear cascades.\\\\ \\\\ In order to investigate the antiproton-nucleus interaction and the processes following the antiproton annihilation at the nucleus, we propose the following experiments: \\item A)~Measurement of several fragments from fission and from multifragmentation in coincidence with particle spectra, especially neutrons and kaons. \\item B)~Precise spectra of $\\pi$, K, n, p, d and t with time-of-flight techniques. \\item C)~Installation of the Berlin 4$\\pi$ neutron detector with a 4$\\pi$ Si detector placed inside for fragments and charged particles. This yields neutron multiplicity distributions and consequently distributions of thermal excitation energies and...

  8. Clustering in stable and exotic nuclei

    CERN Document Server

    Beck, C

    2016-01-01

    Since the pioneering discovery of molecular resonances in the 12C+12C reaction more than half a century ago a great deal of research work has been undertaken in alpha clustering. Our knowledge on physics of nuclear molecules has increased considerably and nuclear clustering remains one of the most fruitful domains of nuclear physics, facing some of the greatest challenges and opportunities in the years ahead. The occurrence of "exotic" shapes and Bose-Einstein alpha condensates in light N=Z alpha-conjugate nuclei is investigated. Various approaches of the superdeformed and hyperdeformed bands associated with quasimolecular resonant structures are presented. Evolution of clustering from stability to the drip-lines is examined: clustering aspects are, in particular, discussed for light exotic nuclei with large neutron excess such as neutron-rich Oxygen isotopes with their complete spectroscopy.

  9. Electron interactions with nuclei: Progress report

    International Nuclear Information System (INIS)

    High energy is being conducted at the Stanford Linear Accelerator Center. This includes inclusive electron scattering, electroexcitation of the delta in nuclei, longitudinal and transverse response in the quasi-elastic region, the q2 dependence of 4He(e,e'p), deep inelastic scattering from nuclei, transverse and longitudinal response in the resonance region, nuclear physics at PEP and 1.6 GeV spectrometer properties. Additional high energy research on electron scattering on 3H and 3He and the nuclear structure of 205Tl and 206Pb are being conducted at MIT-Bates. Other activities are being carried out at Saclay and research and development for Monte Carlo studies of Hall A spectrometers for CEBAF is being conducted

  10. Photoproduction of pi0-mesons from nuclei

    CERN Document Server

    Krusche, B; Ahrens, J; Annand, J R M; Beck, R; Bloch, Felix; Fog, L S; Hornidge, D; Janssen, S; Kotulla, M; McGeorge, J C; MacGregor, I J D; Messchendorp, J; Metag, V; Mosel, U; Novotny, R; Owens, R O; Pfeiffer, M; Sanderson, R; Schadmand, S; Watts, D P

    2004-01-01

    Photoproduction of neutral pions from nuclei (carbon, calcium, niobium, lead) has been studied for incident photon energies from 200 MeV to 800 MeV with the TAPS detector using the Glasgow photon tagging spectrometer at the Mainz MAMI accelerator. Data were obtained for the inclusive photoproduction of neutral pions and the partial channels of quasifree single pi0, double pi0, and pi0pi+/- photoproduction. They have been analyzed in terms of the in-medium behavior of nucleon resonances and the pion - nucleus interaction. They are compared to earlier measurements from the deuteron and to the predictions of a Boltzmann-Uehling-Uhlenbeck (BUU) transport model for photon induced pion production from nuclei.

  11. Simulation of nuclei morphologies for binary alloy

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    We study the critical nuclei morphologies of a binary alloy by the string method. The dynamic equation of the string, connecting the metastable phase (liquid) and stable phase (solid), is governed by Helmholtz free energy for the binary alloy system at a given temperature. The stationary string through the critical nucleus (saddle point) is obtained if the relaxation time of the string is su?ciently large. The critical nucleus radius and energy barrier to nucleation of a pure alloy with isotropic interface energy in two and three dimensions are calculated, which are consistent with the classical nucleation theory. The critical nuclei morphologies are sensitive to the anisotropy strength of interface energy and interface thickness of alloy in two and three dimensions. The critical nucleus and energy barrier to nucleation become smaller if the anisotropy strength of the interface energy is increased, which means that it is much easier to form a stable nucleus if the anisotropy of the interface energy is considered.

  12. Cumulative processes and quark distribution in nuclei

    International Nuclear Information System (INIS)

    Assuming existence of multiquark (mainly 12q) bags in nuclei the spectra of cumulative nucleons and mesons produced in high-energy particle-nucleus collisions are discussed. The exponential form of quark momentum distribution in 12q-bag (agreeing well with the experimental data on lepton-nucleus interactions at large q2) is shown to result in quasi-exponential distribution of cumulative particles over the light-cone variable αsub(B). The dependence of f(αsub(B); psub(perpendicular)) (where psub(perpendicular) is the transverse momentum of the bag) upon psub(perpendicular) is considered. The yields of cumulative resonances as well as effects related to the u- and d-quark distributions in N > Z nuclei being different are dicscussed

  13. Nuclei at HERA and heavy ion physics

    Energy Technology Data Exchange (ETDEWEB)

    Gavin, S. [Brookhaven National Lab., Upton, NY (United States); Strikman, M. [Pennsylvania State Univ., University Park, PA (United States)

    1995-12-31

    Copies of 16 viewgraph sets from a workshop held at Brookhaven National Laboratory, 17-18 November, 1995. Titles of talks: HERA: The Present; HERA: Potential with Nuclei; Review of Hadron-Lepton Nucleus Data; Fermilab E665: results in muon scattering; Interactions of Quarks and Gluons with Nuclear Matter; Rescattering in Nuclear Targets for Photoproduction and DIS; Structure Functions and Nuclear Effect at PHENIX; Probing Spin-Averaged and Spin-Dependent Parton Distributions Using the Solenoidal Tracker at RHIC (STAR); Jet Quenching in eA, pA, AA; Nuclear Gluon Shadowing via Continuum Lepton Pairs; What can we learn from HERA with a colliding heavy ion beam? The limiting curve of leading particles at infinite A; Coherent Production of Vector Mesons off Light Nuclei in DIS; A Model of High Parton Densities in PQCD; Gluon Production for Weizaecker-Williams Field in Nucleus-Nucleus Collisions; Summary Talk.

  14. Nuclear structure investigations on spherical nuclei

    International Nuclear Information System (INIS)

    This report discusses the following topics: electron scattering studies on spherical nuclei; electron scattering from collective states in deformed nuclei; proton and pion scattering studies; 12C(e,e'p) and 16O(e,e'p); 12C(e,e'α) and 16O(e,e'α); studies at high q at Bates; measurements with rvec e at Bates; 12C(γ,p); future directions in giant resonance studies; proton knockout from 16O; quasielastic studies at Bates; triple coincidence studies of nuclear correlations; contributions to (e,e'2p) at KIKHEF; contributions to instrumentation at CEBAF; instrumentation development at UNH; the Bates large acceptance spectrometer toroid; shell model and core polarization calculations; and the relativistic nuclear model

  15. Heavy fragments emission from highly excited nuclei

    International Nuclear Information System (INIS)

    In the intermediate energy domain, the high amount of excitation energy and angular momentum deposited in the nuclei allow the emission of fragments heavier than the usual evaporation particles to have a significant cross section. The study of the properties characterizing the production of these fragments could be a good way to investigate the mechanisms which contribute to formation of hot nuclei and the limits for linear momentum and excitation energy deposited in the nucleus, as well as possible deformations related to these high temperatures. These phenomena might depend much on the center of mass energies and angular momenta. In order to analyse these entrance channel effects3, we chose to study the following systems: Kr + C, Kr + Al, Kr + Ti at an incident energy of the Kr beam delivered by GANIL of 2216 MeV. 7 figs, 1 tab, 9 refs

  16. Nuclei at HERA and heavy ion physics

    International Nuclear Information System (INIS)

    Copies of 16 viewgraph sets from a workshop held at Brookhaven National Laboratory, 17-18 November, 1995. Titles of talks: HERA: The Present; HERA: Potential with Nuclei; Review of Hadron-Lepton Nucleus Data; Fermilab E665: results in muon scattering; Interactions of Quarks and Gluons with Nuclear Matter; Rescattering in Nuclear Targets for Photoproduction and DIS; Structure Functions and Nuclear Effect at PHENIX; Probing Spin-Averaged and Spin-Dependent Parton Distributions Using the Solenoidal Tracker at RHIC (STAR); Jet Quenching in eA, pA, AA; Nuclear Gluon Shadowing via Continuum Lepton Pairs; What can we learn from HERA with a colliding heavy ion beam? The limiting curve of leading particles at infinite A; Coherent Production of Vector Mesons off Light Nuclei in DIS; A Model of High Parton Densities in PQCD; Gluon Production for Weizaecker-Williams Field in Nucleus-Nucleus Collisions; Summary Talk

  17. Effective Field Theory for Lattice Nuclei

    Science.gov (United States)

    Barnea, N.; Contessi, L.; Gazit, D.; Pederiva, F.; van Kolck, U.

    2015-02-01

    We show how nuclear effective field theory (EFT) and ab initio nuclear-structure methods can turn input from lattice quantum chromodynamics (LQCD) into predictions for the properties of nuclei. We argue that pionless EFT is the appropriate theory to describe the light nuclei obtained in LQCD simulations carried out at pion masses heavier than the physical pion mass. We solve the EFT using the effective-interaction hyperspherical harmonics and auxiliary-field diffusion Monte Carlo methods. Fitting the three leading-order EFT parameters to the deuteron, dineutron, and triton LQCD energies at mπ≈800 MeV , we reproduce the corresponding alpha-particle binding and predict the binding energies of mass-5 and mass-6 ground states.

  18. Effective Field Theory for Lattice Nuclei

    CERN Document Server

    Barnea, N; Gazit, D; Pederiva, F; van Kolck, U

    2013-01-01

    We show how nuclear effective field theory (EFT) and ab initio nuclear-structure methods can turn input from lattice quantum chromodynamics (LQCD) into predictions for the properties of nuclei. We argue that pionless EFT is the appropriate theory to describe the light nuclei obtained in recent LQCD simulations carried out at pion masses much heavier than the physical pion mass. We solve the EFT using the effective-interaction hyperspherical harmonics and auxiliary-field diffusion Monte Carlo methods. Fitting the three leading-order EFT parameters to the deuteron, dineutron and triton LQCD energies at $m_{\\pi}\\approx 800$ MeV, we reproduce the corresponding alpha-particle binding and predict the binding energies of mass-5 and 6 ground states.

  19. Octupole vibrations in rare-earth nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Buessing, Marc Andre; Elvers, Michael; Endres, Janis; Hasper, Jens; Zilges, Andreas [Institut fuer Kernphysik, Universitaet Koeln, D-50823 Koeln (Germany)

    2009-07-01

    The systematics of octupole vibrations in the region of rare-earth nuclei are still not well understood. First test measurements have been carried out at the FN Tandem accelerator of the University of Cologne. The gamma-ray spectroscopy was performed at the highly-efficient HORUS spectrometer which consists of 16 High-Purity Germanium detectors. The nucleus {sup 158}Dy has been investigated via the reactions {sup 156}Gd({alpha},2n) and {sup 149}Sm({sup 12}C,3n), furthermore the nucleus {sup 154}Dy was studied via the reaction {sup 144}Nd({sup 14}N,4n). In addition measurements with the (p,p{sup '}) reaction were carried out on the nuclei {sup 142}Nd and {sup 172}Yb. First results of these measurements are shown in the context of existing data for this mass region.

  20. Isospin Mixing In N $\\approx$ Z Nuclei

    CERN Multimedia

    Srnka, D; Versyck, S; Zakoucky, D

    2002-01-01

    Isospin mixing in N $\\approx$ Z nuclei region of the nuclear chart is an important phenomenon in nuclear physics which has recently gained theoretical and experimental interest. It also forms an important nuclear physics correction in the precise determination of the $ft$-values of superallowed 0$^+ \\rightarrow 0^+ \\beta$- transitions. The latter are used in precision tests of the weak interaction from nuclear $\\beta$- decay. We propose to experimentally measure isospin mixing into nuclear ground states in the N $\\approx$ Z region by determining the isospin forbidden Fermi-component in the Gamow-Teller dominated $J^{\\pi} \\rightarrow J^{\\pi} \\beta$- transitions through the observation of anisotropic positron emission from oriented nuclei. First measurements were carried out with $^{71}$As and are being analyzed now.

  1. Octupole correlations in U and Pu nuclei

    International Nuclear Information System (INIS)

    We study the even-even U and Pu nuclei in the framework of the spdf interacting boson model. Analysis of the systematics of positive and negative parity bands, together with the E1, E2, and E3 transitions, suggests that the properties of low-lying states can be understood without the introduction of stable octupole deformation. Double octupole phonon characteristics are also identified in certain low-lying 0+ excited states in U and Pu

  2. QCD Effects in Particle Production on Nuclei

    OpenAIRE

    Hoyer, Paul

    1993-01-01

    I discuss some questions related to hard scattering processes in nuclei and corrections to the leading twist approximation. The QCD factorization theorem requires that high energy partons do not lose energy while traversing the nucleus. I explain the physical reason for this. The theorem also states that spectator partons, not involved in the hard collision, have no influence on the inclusive cross section. Important spectator effects are, however, seen in the data for certain reactions and i...

  3. Deuteron Stripping on Nuclei at Intermediate Energies

    CERN Document Server

    Kovalchuk, V I

    2016-01-01

    A general analytical expression for the double differential cross section of inclusive deuteron stripping reaction on nuclei at intermediate energies of incident particles was obtained in the diffraction approximation. Nucleon-nucleus phases were calculated in the framework of Glauber formalism and making use of the double-folding potential. The exact wave function of deuteron with correct asymptotics at short and long distances between nucleons was used. The calculated angular dependencies of cross sections are in good agreement with corresponding experimental data.

  4. Mean Field Studies of Exotic Nuclei}

    OpenAIRE

    Chinn, C. R.; Umar, A. S.; Vallières, M.; Strayer, M. R.

    1994-01-01

    {Full three dimensional static and dynamic mean field calculations using collocation basis splines with a Skyrme type Hamiltonian are described. This program is developed to address the difficult theoretical challenges offered by exotic nuclei. Ground state and deformation properties are calculated using static Hartree-Fock, Hartree-Fock+BCS and constrained Hartree-Fock models. Collective properties, such as reaction rates and resonances, are described using a new alternate method for evaluat...

  5. Fission Barriers of Compound Superheavy Nuclei

    OpenAIRE

    Pei, J C; Nazarewicz, W.; Sheikh, J. A.; Kerman, A. K.

    2009-01-01

    The dependence of fission barriers on the excitation energy of the compound nucleus impacts the survival probability of superheavy nuclei synthesized in heavy-ion fusion reactions. In this work, we investigate the isentropic fission barriers by means of the self-consistent nuclear density functional theory. The relationship between isothermal and isentropic descriptions is demonstrated. Calculations have been carried out for $^{264}$Fm, $^{272}$Ds, $^{278}$112, $^{292}$114, and $^{312}$124. F...

  6. Stability and Production of Superheavy Nuclei

    OpenAIRE

    Moller, Peter; Nix, J. Rayford

    1997-01-01

    Beyond uranium heavy elements rapidly become increasingly unstable with respect to spontaneous fission as the proton number Z increases, because of the disruptive effect of the long-range Coulomb force. However, in the region just beyond Z = 100 magic proton and neutron numbers and the associated shell structure enhances nuclear stability sufficiently to allow observation of additional nuclei. Some thirty years ago it was speculated that an island of spherical, relatively stable superheavy nu...

  7. On stable nuclei mass charge distribution

    International Nuclear Information System (INIS)

    The charge distribution of mass averaged stable nuclei about trajectory that cross the points with proton and neutron numbers nearly magic is investigated. It is shown that the charge distribution of ΔM have a symmetric property on nucleus charge z=45 and mass number A=103. The distribution of ΔM is compared with charge distribution of product of 206Th fission in framework of statistic model. 4 refs.; 1 fig. (author)

  8. Pairing and specific heat in hot nuclei

    OpenAIRE

    Gambacurta, Danilo; Lacroix, Denis; Sandulescu, Nicu

    2013-01-01

    The thermodynamics of pairing phase-transition in nuclei is studied in the canonical ensemble and treating the pairing correlations in a finite-temperature variation after projection BCS approach (FT-VAP). Due to the restoration of particle number conservation, the pairing gap and the specific heat calculated in the FT-VAP approach vary smoothly with the temperature, indicating a gradual transition from the superfluid to the normal phase, as expected in finite systems. We have checked that th...

  9. Nuclear magnetic resonance of thermally oriented nuclei

    International Nuclear Information System (INIS)

    The more recent developments in the spectroscopy of Nuclear Magnetic Resonance on Oriented Nuclei (NMRON) are reviewed; both theoretical and experimental advances are summarised with applications to On-Line and Off-Line determination of magnetic dipole and electric quadrupole hyperfine parameters. Some emphasis is provided on solid state considerations with indications of where likely enhancements in technique will lead in conventional hyperfine studies. (orig.)

  10. On Closed Shells in Nuclei. II

    Science.gov (United States)

    Mayer, M. G.

    1949-04-01

    Discussion on the use of spins and magnetic moments of the even-odd nuclei by Feenberg and Nordheim to determine the angular momentum of the eigenfunction of the odd particle; discussion of prevalence of isomerism in certain regions of the isotope chart; tabulated data on levels of square well potential, spectroscopic levels, spin term, number of states, shells and known spins and orbital assignments.

  11. How do nuclei really vibrate or rotate

    International Nuclear Information System (INIS)

    By means of the adiabatic cranking model the properties of the current and velocity fields of nuclear quadrupole vibrations for even-even nuclei in the rare-earth region are investigated. BCS correlated wave functions based on the Nilsson single particle Hamiltonian have been used. The current fields are analyzed in terms of vector spherical harmonics. The realistic microscopic currents show a vortex structure not present in the classical irrotational flow. The microscopic origin of the vortex structure is investigated

  12. Fayans functional for deformed nuclei. Uranium region

    CERN Document Server

    Tolokonnikov, S V; Kortelainen, M; Lutostansky, Yu S; Saperstein, E E

    2015-01-01

    Fayans energy density functional (EDF) FaNDF^0 has been applied to the nuclei around uranium region. Ground state characteristics of the Th, U and Pu isotopic chains, up to the two-neutron drip line, are found and compared with predictions from several Skyrme EDFs. The two-neutron drip line is found for FaNDF^0, SLy4 and SkM^* EDFs for a set of elements with even proton number, from Pb up to Fm.

  13. Nuclear moments of radioactive nuclei. Final report

    International Nuclear Information System (INIS)

    An unsuccessful attempt was made to study nuclear moments of radioactive nuclear using laser spectroscopy. Although preliminary tests had indicated a sensitivity sufficient to observe signals of fluxes less than one atom/s no resonance fluorescence was detected. Activity measurements showed several hundred nuclei per second were in the beam; therefore it was postulated that, due to the the reactivity of the 126Ba and sodium used, contaminants were the probable source of negative results. 3 refs., 2 figs

  14. On minor black holes in galactic nuclei

    OpenAIRE

    McKernan, Barry; Ford, K. E. Saavik; Yaqoob, Tahir; Winter, Lisa M.

    2011-01-01

    Small and intermediate mass black holes should be expected in galactic nuclei as a result of stellar evolution, minor mergers and gravitational dynamical friction. If these minor black holes accrete as X-ray binaries or ultra-luminous X-ray sources, and are associated with star formation, they could account for observations of many low luminosity AGN or LINERs. Accreting and inspiralling intermediate mass black holes could provide a crucial electromagnetic counterpart to strong gravitational ...

  15. Chiral bags, skyrmions and quarks in nuclei

    International Nuclear Information System (INIS)

    Recent developments on an intriguing connection between the quark-bag description of the baryons (nucleons in particular) and the Skyrmion model are discussed in terms of the constraints coming from chiral anomalies. Topics treated are the leaking baryon charge, axial charge and energy density; the role of chiral anomalies; the role of Skyrme's quartic term and the connection to the meson degrees of freedom; and finally some qualitative implications in nuclei. The presentation is purposely descriptive and intuitive instead of mathematically precise

  16. The interactions of heavy mesons with nuclei

    International Nuclear Information System (INIS)

    Data obtained from interactions of heavy mesons with nuclei is reviewed. Nucleon-nucleon reactions followed by p + d (or d+p) reactions and nucleon-nucleus reactions are described. A meson decay experiment is discussed. The fundamental importance of S11 (1535) in η-nucleon is stressed. The propagation of resonances through nuclear matter is considered. Improvements in this research field require the developement of a new accelerator generation

  17. Structure of residual interaction in spherical nuclei

    OpenAIRE

    Kamchatnov, A. M.; Nosov, V. G.

    2003-01-01

    The effect of residual interaction between nucleons (quasiparticles) on shell oscillations of the masses of spherical nuclei is considered. The singularity of the ground state energy of the system in the vicinity of nucleon magic numbers is analyzed for various types of the dependence of residual interaction on orbital momentum of the quasiparticle. It is shown that only the perturbation band width of the Fermi distribution due to residual interaction which is proportional to the square of th...

  18. Microscopic approaches to complex excitations in nuclei

    OpenAIRE

    Bianco, Davide

    2011-01-01

    Studying the spectroscopic properties of nuclei in terms of their nucleonic degrees of freedom is one of the most challenging tasks in nuclear structure physics. In principle, the nuclear Shell Model (SM) allows to solve exactly the nuclear eigenvalue problem. Its actual implementation, however, presents several problems. One has first to turn the eigenvalue problem in the full space into an equivalent one formulated in a restricted model space. In order to achieve this step, it is necess...

  19. Light nuclei production in heavy ion collisions

    OpenAIRE

    K.H. Khan; Suleymanov, M. K.; Wazir, Z.; Khan, E. U.; Haseeb, Mahnaz Q.; Ajaz, M.

    2009-01-01

    Light nuclei production as a result of nuclear coalescence effect can give some signals on final state of Quark Gluon Plasma formation. We are studying the behavior of nuclear modification factor as a function of different variables using the simulated data coming from the FASTMC generator. This data is necessary to extract information on coalescence mechanism from experimental data on high energy nuclear-nuclear interactions.

  20. Fission of nuclei far from stability

    International Nuclear Information System (INIS)

    The secondary-beam facility of GSI provided the technical equipment for a new kind of fission experiment. Fission properties of short-lived neutron-deficient nuclei have been investigated in inverse kinematics. The measured element distributions reveal new kinds of systematics on shell structure and even-odd effects and lead to an improved understanding of structure effects in nuclear fission. Prospects for further experimental studies are discussed. (orig.)

  1. Search for nuclei containing two strange quarks

    International Nuclear Information System (INIS)

    This paper discusses a search for nuclei containing two strange quarks performed at Brookhaven National Laboratory. The goals and approach of experiment E885 are reviewed. Preliminary missing mass spectra for a subset of the data are presented, showing sensitivity for Ξ hypernuclei and H particle searches. Existence of an angular correlation between pions in the sequential decay of ΛΛ hypernuclei is suggested on theoretical grounds

  2. Study of shape changes of rotating nuclei

    International Nuclear Information System (INIS)

    The systematic calculation of the rotational band heads was performed for 65 < Z < 81 nuclei. The equilibrium deformations have been determined for each band-head separately and a comparison with several hundreds of levels known experimentally has been given. Also, the calculations of the total energy surfaces with pairing using the mean-pairing field ansatz have been given. The first results were illustrated on the shape-coexistence effects in N = 87 isotones

  3. Multifragmentation of hot and compressed nuclei

    International Nuclear Information System (INIS)

    A proper description of this phenomenon has to go beyond the conventional mean field approaches. One usually refer to the important many-body correlations as the fluctuations of the mean field. They become especially important when the density of the medium becomes small. Several theoretical approaches attempt to understand and describe the multifragmentation of nuclei. We present the main physical ideas which we have used to describe the onset of multifragmentation. We also present the most interesting results that we have obtained

  4. Green's function calculations of light nuclei

    Science.gov (United States)

    Sun, ZhongHao; Wu, Qiang; Xu, FuRong

    2016-09-01

    The influence of short-range correlations in nuclei was investigated with realistic nuclear force. The nucleon-nucleon interaction was renormalized with V lowk technique and applied to the Green's function calculations. The Dyson equation was reformulated with algebraic diagrammatic constructions. We also analyzed the binding energy of 4He, calculated with chiral potential and CD-Bonn potential. The properties of Green's function with realistic nuclear forces are also discussed.

  5. Fourth nuclear theory workshop 'clusters in nuclei'

    International Nuclear Information System (INIS)

    This document gathers the slides of 3 lectures: 1) the R-matrix method, 2) from realistic NN-interactions to cluster structures in nuclei - in this part the unitary correlation operator method (UCOM) is applied to 3 domains: the fermionic molecular dynamics, the Hartree-Fock approximation, and the no-core shell model -, and 3) the shell model point of view on cluster states

  6. History of cluster structure in nuclei

    International Nuclear Information System (INIS)

    This contribution focuses on the history of clustering in nuclei. Elementary alpha models treat light 4-n nuclei as systems of alpha-particles obeying Bose Einstein statistics. These models neglect the internal structure of the alphas and effects of the Pauli principle between the nucleons in the alpha clusters are taken into account by introducing a short range repulsion between the clusters. The orthogonality condition model and excluded state model treat the alphas as elementary particles, but include effects of the Pauli principle in a more microscopic way. Wheeler's resonating group method is a fully microscopic theory for calculating properties of cluster systems. It makes simplifying assumptions about the internal structure of the clusters but takes the Pauli principle explicitly. Hartree-Fock theory can be used for a microscopic theory of nuclear structure but it is not suitable for light nuclei because there is no well defined mean field. Margenau's microscopic cluster model avoids this problem by using trial wave functions which are antisymmetrized products of parametrized single particle wave functions

  7. Fusion excitation functions involving transitional nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Rehm, K.E.; Jiang, C.L.; Esbensen, H. [and others

    1995-08-01

    Measurements of fusion excitation functions involving transitional nuclei {sup 78}Kr and {sup 100}Mo showed a different behavior at low energies, if compared to measurements with {sup 86}Kr and {sup 92}Mo. This points to a possible influence of nuclear structure on the fusion process. One way to characterize the structure of vibrational nuclei is via their restoring force parameters C{sub 2} which can be calculated from the energy of the lowest 2{sup +} state and the corresponding B(E2) value. A survey of the even-even nuclei between A = 28-150 shows strong variations in C{sub 2} values spanning two orders of magnitude. The lowest values for C{sub 2} are observed for {sup 78}Kr, {sup 104}Ru and {sup 124}Xe followed by {sup 74,76}Ge, {sup 74,76}Se, {sup 100}Mo and {sup 110}Pd. In order to learn more about the influence of {open_quotes}softness{close_quotes} on the sub-barrier fusion enhancement, we measured cross sections for evaporation residue production for the systems {sup 78}Kr + {sup 104}Ru and {sup 78}Kr + {sup 76}Ge with the gas-filled magnet technique. For both systems, fusion excitation functions involving the closed neutron shell nucleus {sup 86}Kr were measured previously. The data are presently being analyzed.

  8. Few-Body Models of Light Nuclei

    Science.gov (United States)

    Ershov, S. N.; Vaagen, J. S.; Zhukov, M. V.

    2015-06-01

    Experiments confirm a variety of cluster structures in many light nuclei. The observation of nuclear halos at drip-lines has accentuated the question of the degrees of freedom for bound and low-lying continuum states. In these cases the many-body dynamics of nuclear structure may be well approximated by few-body cluster models that often suggest conceptually simple approaches explaining successfully many features of light nuclei. Thus few-body cluster models have been successfully used for description of the nuclear structure of weakly bound halo nuclei and their emergent cluster degrees of freedom. They have attractive features supplying in a most transparent way the asymptotic behavior and continuum properties of weakly bound systems. Such models assume a separation in internal cluster (core) degrees of freedom and the relative motion of few-body constituents. Such separation is only an approximation, and low-lying states appear where the core cannot be considered as inert system and additional degrees of freedom connected to excited core states have to be taken into account. For fixed total angular momentum a coupling to excited core states having different spins involves additional partial waves into the consideration. This allows to account for some emergent (collective) core degrees of freedom and gives a more realistic description of nuclear properties. It is an analogue to increasing the number of shells within the framework of shell-model approaches. Some examples from recent nuclear structure exploration within few-body halo cluster models are presented.

  9. Adiabatic fission barriers in superheavy nuclei

    CERN Document Server

    Jachimowicz, P; Skalski, J

    2016-01-01

    Using the microscopic-macroscopic model based on the deformed Woods-Saxon single-particle potential and the Yukawa-plus-exponential macroscopic energy we calculated static fission barriers $B_{f}$ for 1305 heavy and superheavy nuclei $98\\leq Z \\leq 126$, including even - even, odd - even, even - odd and odd - odd systems. For odd and odd-odd nuclei, adiabatic potential energy surfaces were calculated by a minimization over configurations with one blocked neutron or/and proton on a level from the 10-th below to the 10-th above the Fermi level. The parameters of the model that have been fixed previously by a fit to masses of even-even heavy nuclei were kept unchanged. A search for saddle points has been performed by the "Imaginary Water Flow" method on a basic five-dimensional deformation grid, including triaxiality. Two auxiliary grids were used for checking the effects of the mass asymmetry and hexadecapole non-axiallity. The ground states were found by energy minimization over configurations and deformations...

  10. A Search for "Dwarf" Seyfert Nuclei; 4, Nuclei with Broad H-$\\alpha$ Emission

    CERN Document Server

    Ho, L C; Sargent, W L W; Peng, C Y; Ho, Luis C.; Filippenko, Alexei V.; Sargent, Wallace L. W.; Peng, Chien Y.

    1997-01-01

    We present the results of an optical spectroscopic survey designed to search for low-luminosity, "dwarf" Seyfert nuclei in a magnitude-limited sample of 486 bright, northern galaxies. Moderate-resolution spectra of exceptionally high quality were obtained in part to detect broad H-alpha emission, similar in character to, but much weaker than, the broad permitted lines that define type 1 Seyfert nuclei. One of the primary goals of the survey is to better quantify the faint end of the luminosity function of active galactic nuclei. This paper describes the subset of nuclei showing definite or probable evidence of broad H-alpha emission. We outline the procedures for determining the presence of this elusive spectral feature, steps for its quantitative measurement, and the associated systematic errors. Of the 211 emission-line galaxies classified as having Seyfert or LINER nuclei in our survey, the broad H-alpha line was detected with confidence in 34 objects, and with less certainty in another 12. Most of the det...

  11. Interaction of eta mesons with nuclei

    Science.gov (United States)

    Kelkar, N. G.; Khemchandani, K. P.; Upadhyay, N. J.; Jain, B. K.

    2013-06-01

    Back in the mid-1980s, a new branch of investigation related to the interaction of eta mesons with nuclei came into existence. It started with the theoretical prediction of possible exotic states of eta mesons and nuclei bound by the strong interaction and later developed into an extensive experimental program to search for such unstable states as well as understand the underlying interaction via eta-meson producing reactions. The vast literature of experimental as well as theoretical works that studied various aspects of eta-producing reactions such as the π+n → ηp, pd → 3Heη, p 6Li → 7Be η and γ 3He → η X, to name a few, had but one objective in mind: to understand the eta-nucleon (ηN) and hence the η-nucleus interaction which could explain the production data and confirm the existence of some η-mesic nuclei. In spite of these efforts, there remain uncertainties in the knowledge of the ηN and hence the η-nucleus interaction. Therefore, this review is an attempt to bind together the findings in these works and draw some global and specific conclusions which can be useful for future explorations. The ηN scattering length (which represents the strength of the η-nucleon interaction) using different theoretical models and analyzing the data on η production in pion, photon and proton induced reactions was found to be spread out in a wide range, namely, 0.18 ⩽ ℜe aηN ⩽ 1.03 fm and 0.16 ⩽ ℑm aηN ⩽ 0.49 fm. Theoretical searches of heavy η-mesic nuclei based on η-nucleus optical potentials and lighter ones based on Faddeev type few-body approaches predict the existence of several quasibound and resonant states. Although some hints of η-mesic states such as ^3_{\\eta} He and ^{25}_{\\eta} Mg do exist from previous experiments, the promise of clearer signals for the existence of η-mesic nuclei lies in the experiments to be performed at the J-PARC, MAMI and COSY facilities in the near future. This review is aimed at giving an overall

  12. Characterization of Acremonium and Isaria ice nuclei

    Science.gov (United States)

    Pummer, Bernhard G.; Pöschl, Ulrich; Fröhlich-Nowoisky, Janine

    2014-05-01

    Until recently, the only known fungal ice nuclei (IN) were a few exponents of lichen mycobionts and Fusarium spp. [Kieft and Ruscetti 1990, Pouleur et al. 1992, Hasegawa et al. 1994, Tsumuki et al. 1995], as well as two strains of mold [Jayaweera and Flanagan 1982]. Other investigated species did not show any IN activity [Pouleur et al. 1992, Iannone et al. 2011, Pummer et al. 2013]. In the last few years, IN-activity has been discovered in some rust and smut fungi [Morris et al. 2013, Haga et al. 2013], Acremonium implicatum (Acr.) and Isaria farinosa (Isa.) [Huffman et al. 2013] and a handful of other airborne and soil fungi [unpublished data]. We started characterizing the IN of Acr. and Isa.: Like other non-bacterial biological IN, they can be easily separated from the cells in aqueous suspension, and keep their activity. The IN-active aqueous suspensions were processed by filtration (5 μm, 0.1 μm, 300 kDa, 100 kDa) and exposure to heat (60° C) or guanidinium chloride (6 M). The IN activity of the processed samples was measured by a freezing assay of droplets, as described by Pummer et al. [2013]. Via the Vali formula, we calculated the amount of IN per gram of mycelium, which is higher than 105 g-1. The initial freezing temperature was -4° C for Isaria and -8° C for Acremonium IN. Both were completely knocked out by 60° C or guanidinium chloride. The Acremonium IN are in a mass range between 100 and 300 kDa. The Isaria IN seem to be either a bit larger, or more attached to larger particles, since not all of them pass through the 300-kDa-filter. It is likely that both of these new IN are proteinaceous like the IN of Fusarium spp. and lichen mycobionts, which belong to the Ascomycota phylum. Since the Isaria IN show a high onset freezing temperature and are rather large for single molecules, they might be agglomerates. Haga D.I. et al. (2013) J. Geophys. Res.: Atm. 118, 7260-7272 Hasegawa Y. et al. (1994) Biosci. Biotech. Biochem. 58, 2273-2274 Huffman A

  13. Collisions of Rare Earth Nuclei - a New Reaction Route for Synthesis of Super Heavy Nuclei

    CERN Document Server

    Choudhury, R K

    2012-01-01

    Theories have predicted an island of stability in the super heavy mass region with half lives ranging from a few seconds to a few thousands of years. Extensive efforts are being made experimentally to reach these nuclei in the region of Z = 110 and above with suitable combinations of proton and neutron numbers. However, the cross sections for production of these nuclei are seen to be in the range of a few pico barns or less, and pose great experimental challenges. We show in the present note that great advantages can be obtained by carrying out heavy ion reactions with suitable combinations of projectile and target nuclei in the rare earth region, that will lead to compound systems with very small excitation energy, and with better neutron/proton ratio for larger stability.

  14. From heavy nuclei to super-heavy nuclei; Des noyaux lourds aux super-lourds

    Energy Technology Data Exchange (ETDEWEB)

    Theisen, Ch

    2003-01-01

    The existence of super-heavy nuclei has been predicted nearly fifty years ago. Due to the strong coulomb repulsion, the stabilisation of these nuclei is possible only through shell effects. The reasons for this fragile stability, as well as the theoretical predictions concerning the position of the island of stability are presented in the first part of this lecture. In the second part, experiments and experimental techniques which have been used to synthesize or search for super-heavy elements are described. Spectroscopic studies performed in very heavy elements are presented in the following section. We close this lecture with techniques that are currently being developed in order to reach the superheavy island and to study the structure of very-heavy nuclei. (author)

  15. Relativistic exotic nuclei as projectile beams. New perspectives of studies on the properties of nuclei

    International Nuclear Information System (INIS)

    Examinations of the production cross-sections and the kinematics permitted refinement of model concepts of the peripheral reactions in exotic nuclei at energies from 100 to 1000 A MeV. Due to the strong selectivity and resolution achieved it was possible to discover a large number of novel isotopes at the fragment separator FRS, despite the relatively low projectile beam intensities of the SIS. The two twice magic nuclei found, Ni 78 and Sn 100, are particularly interesting, as they could not be measured so far with other experimental systems. Fission of relativistic uranium ions proved to be a particularly successful process yielding many medium-heavy, neutron-rich nuclei. Insight into the structure of light neutron halos could be improved. The superlarge spatial dimensions of the nuclear halos is discussed. (orig./CB)

  16. Efeito do número da passagem e do gênero das células doadoras de núcleo no desenvolvimento de bovinos produzidos por transferência nuclear Effect of culture time and gender of nuclei donor cells on bovine development produced by nuclear transfer

    Directory of Open Access Journals (Sweden)

    Giovana Krempel Fonseca Merighe

    2010-10-01

    Full Text Available Objetivou-se com este trabalho avaliar o efeito do número da passagem e do sexo das células doadoras de núcleo no desenvolvimento embrionário e fetal após transferência nuclear. Para isso, oócitos bovinos foram maturados, enucleados e reconstruídos com células somáticas de animal adulto. Após a fusão e ativação química, os zigotos reconstituídos foram cultivados em Charles Rosenkranz 2 (CR2 com monocamada de células da granulosa a 38,8ºC em atmosfera umidificada a 5% de CO2 em ar, durante sete dias, e transferidos para receptoras sincronizadas. As taxas de clivagem e desenvolvimento a blastocisto de embriões reconstruídos com células cultivadas por tempo maior foram inferiores às obtidas com os demais tempos de cultivo. Além disso, os blastocistos produzidos não resultaram no desenvolvimento de uma gestação a termo. Embora a taxa de clivagem em embriões fêmeas tenha sido maior, o número de embriões que atingiram o estádio de blastocisto foi maior nos embriões machos. No período gestacional, fêmeas apresentaram maior taxa de aborto entre 90 e 120 dias de gestação. Esses resultados indicam que células doadoras de núcleos cultivados por longos períodos dificultam a produção de blastocistos e aumentam as chances de perdas durante a gestação. Embriões clonados machos têm maior competência para se desenvolver a blastocisto e resultam em menor taxa de perda gestacional.The objective of this study was to evaluate the effects of culture time and sex of nuclei donor cells on embryo and fetal development after nuclear transfer. Thus, bovine oocytes were matured, enucleated and reconstructed with somatic cells from an adult animal. After fusion and chemical activation, the reconstituted zygotes were cultured in Charles Rosenkranz 2 (CR2 on a granular monolayer cell at 38.8ºC in a humidified atmosphere 5% CO2 in air for seven days, and transferred to synchronized receptors. Cleavage rates and development to

  17. Photoproduction of Mesons off Light Nuclei - The Search for η-Mesic Nuclei

    International Nuclear Information System (INIS)

    Photoproduction of η mesons off light nuclei (d, 3He, 7Li) has been measured at the tagged photon beam of the Mainz MAMI accelerator with the combined Crystal Ball/TAPS detection system. Special attention was given to the threshold behavior of the reactions in view of possible indications for the formation of (quasi-) bound η-nucleus states, so-called η-mesic nuclei. A very strong threshold enhancement of coherent η photoproduction off 3He was found and coherent η photoproduction off 7Li was observed for the first time. Preliminary results will be discussed. (authors)

  18. The dynamics of the nuclei-nuclei interactions at very high energies

    International Nuclear Information System (INIS)

    The lectures on the dynamics of nuclei-nuclei interactions at very high energies, presented in the Summer School on Nuclear Physics and Particle Physics (1988), are shown. The equation of state of the hadronic matter is analyzed, by means of simple models, and some orders of magnitude can be asserted. The main characteristics of the high energy hadronic interactions are recalled. The basis of the dynamics of the relativistic fluids are given. Applications of this dynamics in the description of the space-time evolution of a plasma, generated by heavy ions collision, are carried out

  19. Nuclei at extreme conditions. A relativistic study

    Energy Technology Data Exchange (ETDEWEB)

    Afanasjev, Anatoli [Mississippi State Univ., Mississippi State, MS (United States)

    2014-11-14

    The major goals of the current project were further development of covariant density functional theory (CDFT), better understanding of its features, its application to different nuclear structure and nuclear astrophysics phenomena and training of graduate and undergraduate students. The investigations have proceeded in a number of directions which are discussed in detail in the part “Accomplishments” of this report. We have studied the role of isovector and isoscalar proton-neutron pairings in rotating nuclei; based on available experimental data it was concluded that there are no evidences for the existence of isoscalar proton-neutron pairing. Generalized theoretical approach has been developed for pycnonuclear reaction rates in the crust of neutron stars and interior of white dwarfs. Using this approach, extensive database for considerable number of pycnonuclear reactions involving stable and neutron-rich light nuclei has been created; it can be used in future for the study of various nuclear burning phenomena in different environments. Time-odd mean fields and their manifestations in terminating states, non-rotating and rotating nuclei have been studied in the framework of covariant density functional theory. Contrary to non-relativistic density functional theories these fields, which are important for a proper description of nuclear systems with broken time-reversal symmetry, are uniquely defined in the CDFT framework. Hyperdeformed nuclear shapes (with semi-axis ratio 2.5:1 and larger) have been studied in the Z = 40-58 part of nuclear chart. We strongly believe that such shapes could be studied experimentally in the future with full scale GRETA detector.

  20. The superdeformation phenomenon in atomic nuclei

    Science.gov (United States)

    Meyer, M.; Vivien, J. P.

    After the discovery of discrete rotational bands corresponding to superdeformed nuclei with spin around 60h, the study of the structure of these nuclei over the last five years has witnessed a significant expansion in physical understanding with the emergence of new phenomena and in a technical development with the construction of sophisticated apparatus to examine these nuclei. On the eve of the approaching operation of news detectors such as EUROGAM resulting from a French-British collaboration,or the American GAMMASPHERE, this article discusses the present state of knowledge on superdeformation and exposes the theoretical basis as well as recent experimental results in the field. Avec la découverte de bandes de rotations discrètes correspondant à des noyaux superdéformés ayant des moments angulaires avoisinant 60h, l'étude de la structure de ces noyaux connait depuis les cinq dernières années un essor important tant sur le plan de la physique avec l'apparition de phénomènes nouveaux que sur le plan de la technique avec le développement d'appareillages sophistiqués pour scruter ces noyaux. A la veille de l'entrée en fonction de nouveaux détecteurs comme EUROGAM issu d'une collaboration Franco-Britannique ou GAMMASPHERE résultant des efforts des laboratoires Americains, cet article fait le point des connaissances actuelles sur la superdéformation et relate les acquis théoriques ainsi que les resultats expérimentaux accumulés récemment dans ce domaine.

  1. Modeling a neutron rich nuclei source

    International Nuclear Information System (INIS)

    The deuteron break-up process in a suitable converter gives rise to intense neutron beams. A source of neutron rich nuclei based on the neutron induced fission can be realised using these beams. A theoretical optimization of such a facility as a function of the incident deuteron energy is reported. The model used to determine the fission products takes into account the excitation energy of the target nucleus and the evaporation of prompt neutrons. Results are presented in connection with a converter-target specific geometry. (authors)

  2. AGN variability: from Seyfert nuclei to QSOs

    OpenAIRE

    Aretxaga, Itziar

    1996-01-01

    The continuum variability of optically selected Active Galactic Nuclei (AGN) is found to be consistent with that expected from a simple Poissonian process, in which the total luminosity of an object is produced by the multiple superposition of identical pulses. The energies, time-scales and rates of the pulses are found to be in the range of those expected from supernovae which generate fast evolving remnants in a nuclear starburst.However, radio-loud AGN don't follow the predictions of that ...

  3. Double-beta decay in deformed nuclei

    International Nuclear Information System (INIS)

    A brief review of theoretical results for the double-beta decay and the double-electron capture in heavy deformed nuclei is presented. The ββ half life of 160Gd is evaluated using an extended version of the pseudo SU(3) model. While the 2ν mode is forbidden when the most probable occupations are considered, states with different occupation numbers can be mixed through the pairing interaction. The amount of this mixing is calculated using perturbation theory. The possibility of observing the ββ decay in 160Gd is discussed for both the 2ν and 0ν modes. (author)

  4. Light unstable nuclei in the continuum

    International Nuclear Information System (INIS)

    It is discussed that the complex scaling method is one of the most available frameworks to solve many body resonances. As the recent developments of the complex scaling method, we present several ways to analyse the properties of resonant states; the matrix elements associated with resonant states, the extended completeness relation and partial widths of resonances. We also show the discussions on the binding mechanism and excited resonant structure of the Borromean systems 4He+n+n and 9Li+n+n. It is shown that the pairing correlation between valence neutrons and among core neutrons plays an important role in neutron-rich nuclei. (author)

  5. Electromagnetic properties of nuclei at high spins

    International Nuclear Information System (INIS)

    A photon emitted by an excited state is likely to carry away, at most, 1 or 2 h-bar of angular momentum. Therefore, a profusion of photons is needed to deexcite the rapidly rotating states of nuclei formed by heavy-ion reactions. The study of electromagnetic properties has become the primary source of information on nuclear structure at high spins and, also, at the warm temperatures present in the initial stage of the electromagnetic cascade process. The purpose of this paper is a review of the E1, M1, and E2 properties of such highly excited states. 42 refs., 5 figs

  6. Isovector excitations of N ≠ Z nuclei

    International Nuclear Information System (INIS)

    We show that the method based on the tensor coupling of an appropriate family of isovector excitation operators to the parent isospin multiplet can be used, to advantage, for the correct treatment of the isospin degree of freedom in non isoscalar nuclei. This method is applicable to any isovector excitation operator and for parent states which need not to be of the closed subshells type. As an illustration we apply it to the study of the Gamow-Teller transition strength in 90Zr. (author)

  7. Propagation of heavy cosmic-ray nuclei

    International Nuclear Information System (INIS)

    Techniques for modeling the propagation of heavy cosmic-ray nuclei, and the required atomic and nuclear data, are assembled in this paper. Emphasis is on understanding nuclear composition in the charge range 3< Z<83. Details of the application of ''matrix methods'' above a few hundred meV per nucleon, a new treatment of electron capture decay, and a new table of cosmic-ray-stable isotopes are presented. Computation of nuclear fragmentation cross sections, stopping power, and electron stripping and attachment are briefly reviewed

  8. The Structure of Nuclei Far from Stability

    Energy Technology Data Exchange (ETDEWEB)

    Zganjar, E.F.

    1999-02-25

    From among a number of important nuclear structure results that have emerged from our research program during the past few years, two stand out as being of extra significance. These are: (a) the identification of a diabatic coexisting structure in {sup 187}Au which arises solely from differences in proton occupation of adjacent oscillator shells, and (b) the realization of a method for estimating EO strength in nuclei and the resulting prediction that the de-excitation of superdeformed bands may proceed, in some cases, by strong EO transitions.

  9. A new superfluid phase in atomic nuclei

    International Nuclear Information System (INIS)

    The influence of pairing and the dynamical α-type correlations on the structure of nuclear states is studied within the enlarged superfluid model (ESM). A comparison between ESM and different modern nuclear structure models such as: the quasiparticle-phonon nuclear model, interaction boson model, Hartree-Fock-Bogoliubov, temperature dependent Hartree-Fock-Bogoliubov and Migdal's finite Fermi system model, is done for particular cases. New gap equations are obtained. The phase structure is enriched by a new superfluid phase - the so-called α-like superfluid phase-dominated by α-type correlations. New first and second order phase transitions are predicted. A first order phase transition between the α-like superfluid phase and the pairing superfluid phase seems to be observed in Sm region. New types of isomers, the so-called ''superfluid isomers'', with their bands of elementary excitations are predicted. One of them is observed in 152Sm. These isomers correspond to a second (local) minimum of the correlation energy versus pairing deformations, analogous to the fission or superdeformed (shape) isomers, which correspond to the second (local) minimum of the potential energy along the elongation degree of shape deformation. The superfluidities of neutron and proton systems in heavy nuclei region may be generated by one another. This fact leads to the explanation of the origin of the odd-even staggering of the charge radii of chains of isotopes of different nuclei. The fact that the magnitude of the α-decay reduced widths (γ2) of the neutron-defficient Pb isotopes is almost equal to the γ2 of the actinide α-decaying nuclei is due to the above mentioned induction of the neutron superfluidity into the proton system also. Such exotic data ESM can explain especially in the region of single magic nuclei. Within ESM we could find a natural microscopic description of the scissors mode that dominates the structure of the Kπ=1+ magnetic states. (author). 89 refs, 27 figs

  10. Experimental level densities of atomic nuclei

    International Nuclear Information System (INIS)

    It is almost 80 years since Hans Bethe described the level density as a non-interacting gas of protons and neutrons. In all these years, experimental data were interpreted within this picture of a fermionic gas. However, the renewed interest of measuring level density using various techniques calls for a revision of this description. In particular, the wealth of nuclear level densities measured with the Oslo method favors the constant-temperature level density over the Fermi-gas picture. From the basis of experimental data, we demonstrate that nuclei exhibit a constant-temperature level density behavior for all mass regions and at least up to the neutron threshold. (orig.)

  11. Inclusive inelastic electron scattering from nuclei

    CERN Document Server

    Fomin, Nadia

    2007-01-01

    Inclusive electron scattering from nuclei at large x and $Q^2$ is the result of a reaction mechanism that includes both quasi--elastic scattering from nucleons and deep inelastic scattering from the quark constituents of the nucleons. Data in this regime can be used to study a wide variety of topics, including the extraction of nuclear momentum distributions, the influence of final state interactions and the approach to $y$-scaling, the strength of nucleon-nucleon correlations, and the approach to $x$- scaling, to name a few. Selected results from the recent experiment E02-019 at the Thomas Jefferson National Accelerator Facility will be shown and their relevance discussed.

  12. Two-scale scalar mesons in nuclei

    Energy Technology Data Exchange (ETDEWEB)

    K. Saito; H. Kouno; K. Tsushima; A.W. Thomas

    2005-03-01

    We generalize the linear sigma model in order to develop a chiral-invariant model of nuclear structure. The model is natural, and contains not only the usual sigma meson which is the chiral partner of the pion but also a new chiral-singlet that is responsible for the medium-range nucleon-nucleon attraction. This approach provides significant advantages in terms of its description of nuclear matter and finite nuclei in comparison with conventional models based on the linear sigma model.

  13. Superheavy nuclei – cold synthesis and structure

    Indian Academy of Sciences (India)

    Raj K Gupta

    2001-08-01

    The quantum mechanical fragmentation theory (QMFT), given for the cold synthesis of new and superheavy elements, is reviewed and the use of radioactive nuclear beams (RNB) and targets (RNT) is discussed. The QMFT is a complete theory of cold nuclear phenomena, namely, the cold fission, cold fusion and cluster radioactivity. Also, the structure calculations based on the axially deformed relativistic mean field (DRMF) approach are presented which predict new regions of spherical magicity, namely = 120 and = 172 or 184, for superheavy nuclei. This result is discussed in the light of recent experiments reporting the cold synthesis of = 118 element.

  14. Probing Chiral Interactions in Light Nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Nogga, A; Barrett, B R; Meissner, U; Witala, H; Epelbaum, E; Kamada, H; Navratil, P; Glockle, W; Vary, J P

    2004-01-08

    Chiral two- and three-nucleon interactions are studied in a few-nucleon systems. We investigate the cut-off dependence and convergence with respect to the chiral expansion. It is pointed out that the spectra of light nuclei are sensitive to the three-nucleon force structure. As an example, we present calculations of the 1{sup +} and 3{sup +} states of {sup 6}Li using the no-core shell model approach. The results show contributions of the next-to-next-to-leading order terms to the spectra, which are not correlated to the three-nucleon binding energy prediction.

  15. Light unstable nuclei in the continuum

    Energy Technology Data Exchange (ETDEWEB)

    Kato, Kiyoshi [Hokkaido Univ., Division of Physics, Hokkaido (Japan)

    2000-01-01

    It is discussed that the complex scaling method is one of the most available frameworks to solve many body resonances. As the recent developments of the complex scaling method, we present several ways to analyse the properties of resonant states; the matrix elements associated with resonant states, the extended completeness relation and partial widths of resonances. We also show the discussions on the binding mechanism and excited resonant structure of the Borromean systems {sup 4}He+n+n and {sup 9}Li+n+n. It is shown that the pairing correlation between valence neutrons and among core neutrons plays an important role in neutron-rich nuclei. (author)

  16. Fission properties for r-process nuclei

    OpenAIRE

    Erler, J.; Langanke, K; Loens, H. P.; Martínez-Pinedo, G.; Reinhard, P.-G.

    2011-01-01

    We present a systematics of fission barriers and fission lifetimes for the whole landscape of super-heavy elements (SHE), i.e. nuclei with Z>100. The fission lifetimes are also compared with the alpha-decay half-lives. The survey is based on a self-consistent description in terms of the Skyrme-Hartree-Fock (SHF) approach. Results for various different SHF parameterizations are compared to explore the robustness of the predictions. The fission path is computed by quadrupole constrained SHF. Th...

  17. Shell effect in synthesis of superheavy nuclei

    International Nuclear Information System (INIS)

    The improved isospin dependent quantum molecular dynamics model which includes the shell correction and switch function method is employed to study the synthesis of superheavy nuclei. The shell effect on a fusion process is investigated for 32S+208Pb system. For heavy reaction systems 48Ca+154Sm and 32S+208Pb, the theoretical calculations of fusion cross section are in agreement with the experimental data. The nucleus-nucleus interaction potential is also calculated, and compared with the proximity potential as well. (author)

  18. Signatures for quark clustering in nuclei

    International Nuclear Information System (INIS)

    As a signature for the presence of quark clusters in nuclei, the authors suggest studying backward protons produced by electron scattering off deuterons and suggest a ratio that cancels out much of the detailed properties of deuterons or 6-quark clusters. The test may be viewed as a test that the short range part of the deuteron is still a 2-nucleon system. They make estimates to show how it fails in characteristic and significant ways if the two nucleons at short range coalesce into a kneaded 6-quark cluster

  19. Signature Inversion in Odd-odd Nuclei

    Institute of Scientific and Technical Information of China (English)

    LIU Min-liang; ZHANG Yu-hu; ZHOU Xiao-hong; GUO Ying-xiang; LEI Xiang-guo; GUO Wen-tao

    2009-01-01

    Signature inversion in odd-odd nuclei is investigated by using a proton and a neutron coupling to the coherent state of the core.Two parameters are employed in the Hamiltonian to set the energy scales of rotation,neutron-proton coupling and their competition.Typical level staggering is extracted from the calculated level energies.The calculation can approximately reproduce experimental signature inversion.Signature inversion is attributed to the rotational motion and neutronproton residual interaction having reversed signature splitting rules.It is found signature inversion can appear at axially symmetric shape and high-K band.

  20. The Structure of Nuclei Far from Stability

    International Nuclear Information System (INIS)

    From among a number of important nuclear structure results that have emerged from our research program during the past few years, two stand out as being of extra significance. These are: (a) the identification of a diabatic coexisting structure in 187Au which arises solely from differences in proton occupation of adjacent oscillator shells, and (b) the realization of a method for estimating EO strength in nuclei and the resulting prediction that the de-excitation of superdeformed bands may proceed, in some cases, by strong EO transitions

  1. Synthesis and Properties of Superheavy Nuclei

    International Nuclear Information System (INIS)

    The mechanism of production and decay of excited compound nuclei leading to production of isotopes of trans actinide elements in the vicinity of closed deformed shells Z = 108, N = 162 is being considered. The implementation of experiments is described and data on synthesis of new isotopes 262104, 265,266 106 and 267 108 in hot fusion reactions is presented. The properties of the new nuclides point to a considerable increase of the periods of spontaneous fission predicted by the macro-microscopic theory. Prospects for using fusion reactions in synthesizing new elements are discussed.(author). 30 refs.; 9 figs.; 2 tabs

  2. Effective field theory for deformed atomic nuclei

    CERN Document Server

    Papenbrock, T

    2015-01-01

    We present an effective field theory (EFT) for a model-independent description of deformed atomic nuclei. In leading order this approach recovers the well-known results from the collective model by Bohr and Mottelson. When higher-order corrections are computed, the EFT accounts for finer details such as the variation of the moment of inertia with the band head and the small magnitudes of interband $E2$ transitions. For rotational bands with a finite spin of the band head, the EFT is equivalent to the theory of a charged particle on the sphere subject to a magnetic monopole field.

  3. Signatures for quark clustering in nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Carlson, C.E. [College of William and Mary, Williamsburg, VA (United States); Lassila, K.E. [Iowa State Univ., Ames, IA (United States)

    1994-04-01

    As a signature for the presence of quark clusters in nuclei, the authors suggest studying backward protons produced by electron scattering off deuterons and suggest a ratio that cancels out much of the detailed properties of deuterons or 6-quark clusters. The test may be viewed as a test that the short range part of the deuteron is still a 2-nucleon system. They make estimates to show how it fails in characteristic and significant ways if the two nucleons at short range coalesce into a kneaded 6-quark cluster.

  4. Shapes of non-rotating nuclei

    International Nuclear Information System (INIS)

    We study nuclear potential-energy surfaces, ground-state masses and shapes calculated by use of a Yukawa-plus-exponential macroscopic model and a folded-Yukawa single-particle potential for 4023 nuclei ranging from 16O to 279112. We discuss extensively the transition from spherical to deformed shapes and study the relation between shape changes and the mass corresponding to the ground-state minimum. The calculated values for the ground-state mass and shape show good agreement with experimental data throughout the periodic system, but some discrepancies remain that deserve further study. We also discuss the effect of deformation on Gamow-Teller #betta#-strength functions

  5. Modeling a neutron-rich nuclei source

    International Nuclear Information System (INIS)

    The deuteron break-up process in a suitable converter gives rise to intense neutron beams. A source of neutron-rich nuclei based on the neutron-induced fission can be realised using these beams. A theoretical optimization of such a facility as a function of the incident deuteron energy is reported. The model used to determine the fission products takes into account the excitation energy of the target nucleus and the evaporation of prompt neutrons. Results are presented in connection with a converter-target specific geometry. (orig.)

  6. Enhanced subbarrier fusion for proton halo nuclei

    Science.gov (United States)

    Kumar, Raj; Lay, J. A.; Vitturi, A.

    2014-02-01

    In this Brief Report we use a simple model to describe the dynamical effects of break-up processes in the subbarrier fusion involving weakly bound nuclei. We model two similar cases involving either a neutron or a proton halo nucleus, both schematically coupled to the break-up channels. We find that the decrease of the Coulomb barrier in the proton break-up channel leads, ceteris paribus, to a larger enhancement of the subbarrier fusion probabilities with respect to the neutron halo case.

  7. Enhanced subbarrier fusion for proton halo nuclei

    OpenAIRE

    Kumar, Raj; J.A. Lay; Vitturi, A.

    2014-01-01

    In this short note we use a simple model to describe the dynamical effects of break-up processes in the subbarrier fusion involving weakly bound nuclei. We model two similar cases involving either a neutron or a proton halo nucleus, both schematically coupled to the break-up channels. We find that the decrease of the coulomb barrier in the proton break-up channel leads, ceteris paribus, to a larger enhancement of the subbarier fusion probabilities with respect to the neutron-halo case.

  8. Effective field theory for deformed atomic nuclei

    Science.gov (United States)

    Papenbrock, T.; Weidenmüller, H. A.

    2016-05-01

    We present an effective field theory (EFT) for a model-independent description of deformed atomic nuclei. In leading order this approach recovers the well-known results from the collective model by Bohr and Mottelson. When higher-order corrections are computed, the EFT accounts for finer details such as the variation of the moment of inertia with the band head and the small magnitudes of interband E2 transitions. For rotational bands with a finite spin of the band head, the EFT is equivalent to the theory of a charged particle on the sphere subject to a magnetic monopole field.

  9. Effective field theory for deformed atomic nuclei

    OpenAIRE

    Papenbrock, T.; Weidenmüller, H. A.

    2015-01-01

    We present an effective field theory (EFT) for a model-independent description of deformed atomic nuclei. In leading order this approach recovers the well-known results from the collective model by Bohr and Mottelson. When higher-order corrections are computed, the EFT accounts for finer details such as the variation of the moment of inertia with the band head and the small magnitudes of interband $E2$ transitions. For rotational bands with a finite spin of the band head, the EFT is equivalen...

  10. Light nuclei from chiral EFT interactions

    OpenAIRE

    Navratil, P.; Gueorguiev, V. G.; Vary, J. P.; Ormand, W. E.; Nogga, A.; Quaglioni, S.

    2008-01-01

    Recent developments in nuclear theory allow us to make a connection between quantum chromodynamics (QCD) and low-energy nuclear physics. First, chiral effective field theory (chi EFT) provides a natural hierarchy to define two-nucleon (NN), three-nucleon (NNN), and even four-nucleon interactions. Second, ab-initio methods have been developed capable to test these interactions for light nuclei. In this contribution, we discuss ab-initio no-core shell-model (NCSM) calculations for s-shell and p...

  11. Self-Consistency Effects In Superheavy Nuclei

    International Nuclear Information System (INIS)

    The influence of the central depression in the density distribution of spherical superheavy nuclei on the shell structure is studied within the relativistic mean field theory. Large depression leads to the shell gaps at the proton Z = 120 and neutron N = 172 numbers, while flatter density distribution favors N = 184 for neutrons and leads to the appearance of a Z 126 shell gap and to the decrease of the size of the Z = 120 shell gap. The correlations between the magic shell gaps and the magnitude of central depression are discussed for relativistic and non-relativistic mean field theories

  12. Selected topics on Hadrons in Nuclei

    CERN Document Server

    Oset, E; Hernandez, E; Ramos, A; Magas, V K; Yamagata-Sekihara, J; Hirenzaki, S; Gamermann, D; Molina, R; Tolos, L; Roca, L

    2011-01-01

    In this talk we report on selected topics on hadrons in nuclei. The first topic is the renormalization of the width of the $\\Lambda(1520)$ in a nuclear medium. This is followed by a short update of the situation of the $\\omega$ in the medium. The investigation of the properties of $\\bar{K}$ in the nuclear medium from the study of the $(K_{flight},p)$ reaction is also addressed, as well as properties of X,Y,Z charmed and hidden charm resonances in a nuclear medium. Finally we address the novel issue of multimeson states.

  13. Photoproduction of pions in 12C nuclei

    International Nuclear Information System (INIS)

    A preliminary analysis was carried out of relativistic effects in coherent and incoherent pion production for the reaction 12C(γ, π0)12C by considering all the diagrams that contribute to the scattering amplitude. For the coherent pion the contribution to the scattering cross section mainly comes from the direct and exchange diagrams of γN → Δ → Nπ0, where N is a nucleon. The results were compared with the nonrelativistic calculations done in 12C nuclei assuming the nuclear effects and the final state interactions to be the same

  14. Rings with generalized commutators in the nuclei

    OpenAIRE

    Chen-Te Yen

    2002-01-01

    Let $ R$ be a prime weakly Novikov ring and $ T_k=\\underbrace{[[[\\ldots[[R,R],R]\\ldots,R],R],R]}_{k R's}$ where $ k$ is a positive integer. We prove that if $ T_k\\subseteq N_l\\cap N_r$ or $ T_k\\subseteq N_m\\cap N_r$ then $ R$ is associative or $ T_k=0$. Moreover, if $ T_k$ is contained in two of the three nuclei, and $ k=2$ or $ k=3$ then the same conclusions hold. We also consider such rings with derivations. Some similar results of weakly M-rings are obtained.

  15. Isospin transfer modes in exotic nuclei

    Directory of Open Access Journals (Sweden)

    Litvinova Elena

    2015-01-01

    Full Text Available This work presents an approach to nuclear spin-isospin response, which is capable of describing the overall strength distribution up to high excitation energies, including the fine structure of the low-lying strength, and resolving the long-standing quenching problem. The model is a covariant realization of the nuclear field theory and based on the self-consistent extensions of the covariant energy density functional (CEDF theory. Results of the recent calculations for spin-isospin response of ordinary and exotic medium-mass nuclei are presented and discussed.

  16. Photoproduction of vector mesons in nuclei

    International Nuclear Information System (INIS)

    The mass of vector mesons in the nuclear medium is of great interest in strong interaction dynamics because vector meson masses could decrease with increasing baryonic density as a consequence of chiral symmetry restoration. The purpose of this work is to define an observable sensitive to vector meson masses at nuclear matter density. This short paper reports some preliminary results which suggest that the quantum interference between (e+e-) pairs emitted in the photoproduction of ρ- and ω- mesons near threshold in heavy nuclei could be such quantity. (J.S.). 4 refs., 2 figs

  17. Annular diffraction of very unstable light nuclei

    International Nuclear Information System (INIS)

    Because they are brittle, unstable light nuclei can produce an annular diffraction pattern observed on their decay products with large cross sections. With such a simple model, the 9Li angular distribution observed in the 11Li fragmentation have been reproduced together with the reaction cross-section and the fragmentation yield provided recoil effects from neutron emission are included. It results that for this projectile and for light targets, diffraction is the main source of transverse momentum for 9Li whereas for neutrons it originates from its emission energy in the 11Li center of mass

  18. Search for Hyperdeformation in Light Xe Nuclei

    International Nuclear Information System (INIS)

    The ultimate search for hyperdeformation (HD) at high spins with the EUROBALL spectrometer was performed for 126Ba as a hyper long (HLHD) experiment. The Diamant ancillary detector was used to tag γ-rays in coincidence with the emitted light charged particles. Using γ-energy correlation methods, the particle-x n-γ data have been analysed to search for hyperdeformed structures in the corresponding residual nuclei. Data in coincidence with one particle indicate the presence of normal deformed collective bands up to very high spins and the possible occurrence of HD-like ridge structures in 122Xe. (author)

  19. Search for Hyperdeformation in Light Xe Nuclei

    Science.gov (United States)

    Nyako, B. M.; Papp, F.; Gal, J.; Molnar, J.; Timar, J.; Algora, A.; Dombradi, Zs.; Kalinka, G.; Zolnai, L.; Juhasz, K.; Singh, A. K.; Huebel, H.; Al-Khatib, A.; Bringel, P.; Buerger, A.; Neusser, A.; Schoenwasser, G.; Herskind, B.; Hagemann, G. B.; Hansen, C. R.; Sletten, G.; Scheurer, J. N.; Hannachi, F.; Kmiecik, M.; Maj, A.; Styczen, J.; Zuber, K.; Hauschild, K.; Korichi, A.; Lopez-Martens, A.; Roccaz, J.; Siem, S.; Bednarczyk, P.; Byrski, Th.; Curien, D.; Dorvaux, O.; Duchene, G.; Gall, B.; Khalfallah, F.; Piqueras, I.; Robin, J.; Patel, S. B.; Evans, A. O.; Rainovski, G.; Airoldi, A.; Benzoni, G.; Bracco, A.; Camera, F.; Million, B.; Mason, P.; Paleni, A.; Sacchi, R.; Wieland, O.; La Rana, G.; Moro, R.; Petrache, C. M.; Petrache, D.; de Angelis, G.; Fallon, P.; Lee, I.-Y.; Lisle, J. C.; Cederwall, B.; Lagergren, K.; Lieder, R. M.; Podsvirova, E.; Gast, W.; Jaeger, H.; Redon, N.; Goergen, A.

    2005-04-01

    The ultimate search for hyperdeformation (HD) at high spins with the EUROBALL spectrometer was performed for 126Ba as a hyper long (HLHD) experiment. The DIAMANT ancillary detector was used to tag γ -rays in coincidence with the emitted light charged particles. Using γ -energy correlation methods, the particle--xn-γ data have been analysed to search for hyperdeformed structures in the corresponding residual nuclei. Data in coincidence with one α particle indicate the presence of normal deformed collective bands up to very high spins and the possible occurrence of HD-like ridge structures in 122Xe.

  20. Experimental level densities of atomic nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Guttormsen, M.; Bello Garrote, F.L.; Eriksen, T.K.; Giacoppo, F.; Goergen, A.; Hagen, T.W.; Klintefjord, M.; Larsen, A.C.; Nyhus, H.T.; Renstroem, T.; Rose, S.J.; Sahin, E.; Siem, S.; Tornyi, T.G.; Tveten, G.M. [University of Oslo, Department of Physics, Oslo (Norway); Aiche, M.; Ducasse, Q.; Jurado, B. [University of Bordeaux, CENBG, CNRS/IN2P3, B.P. 120, Gradignan (France); Bernstein, L.A.; Bleuel, D.L. [Lawrence Livermore National Laboratory, Livermore, CA (United States); Byun, Y.; Voinov, A. [Ohio University, Department of Physics and Astronomy, Athens, Ohio (United States); Gunsing, F. [CEA Saclay, DSM/Irfu/SPhN, Cedex (France); Lebois, L.; Leniau, B.; Wilson, J. [Institut de Physique Nucleaire d' Orsay, Orsay Cedex (France); Wiedeking, M. [iThemba LABS, P.O. Box 722, Somerset West (South Africa)

    2015-12-15

    It is almost 80 years since Hans Bethe described the level density as a non-interacting gas of protons and neutrons. In all these years, experimental data were interpreted within this picture of a fermionic gas. However, the renewed interest of measuring level density using various techniques calls for a revision of this description. In particular, the wealth of nuclear level densities measured with the Oslo method favors the constant-temperature level density over the Fermi-gas picture. From the basis of experimental data, we demonstrate that nuclei exhibit a constant-temperature level density behavior for all mass regions and at least up to the neutron threshold. (orig.)

  1. Symmetry energy, unstable nuclei and neutron star crusts

    Energy Technology Data Exchange (ETDEWEB)

    Iida, Kei [Kochi University, Department of Natural Science, Kochi (Japan); RIKEN Nishina Center, Saitama (Japan); Oyamatsu, Kazuhiro [RIKEN Nishina Center, Saitama (Japan); Aichi Shukutoku University, Department of Human Informatics, Aichi (Japan)

    2014-02-15

    The phenomenological approach to inhomogeneous nuclear matter is useful to describe fundamental properties of atomic nuclei and neutron star crusts in terms of the equation of state of uniform nuclear matter. We review a series of researches that we have developed by following this approach. We start with more than 200 equations of state that are consistent with empirical masses and charge radii of stable nuclei and then apply them to describe matter radii and masses of unstable nuclei, proton elastic scattering and total reaction cross sections off unstable nuclei, and nuclei in neutron star crusts including nuclear pasta. We finally discuss the possibility of constraining the density dependence of the symmetry energy from experiments on unstable nuclei and even observations of quasi-periodic oscillations in giant flares of soft gamma-ray repeaters. (orig.)

  2. Precision measurement of the mass difference between light nuclei and anti-nuclei

    CERN Document Server

    Adam, Jaroslav; Aggarwal, Madan Mohan; Aglieri Rinella, Gianluca; Agnello, Michelangelo; Agrawal, Neelima; Ahammed, Zubayer; Ahmed, Ijaz; Ahn, Sang Un; Aimo, Ilaria; Aiola, Salvatore; Ajaz, Muhammad; Akindinov, Alexander; Alam, Sk Noor; Aleksandrov, Dmitry; Alessandro, Bruno; Alexandre, Didier; Alfaro Molina, Jose Ruben; Alici, Andrea; Alkin, Anton; Alme, Johan; Alt, Torsten; Altinpinar, Sedat; Altsybeev, Igor; Alves Garcia Prado, Caio; Andrei, Cristian; Andronic, Anton; Anguelov, Venelin; Anielski, Jonas; Anticic, Tome; Antinori, Federico; Antonioli, Pietro; Aphecetche, Laurent Bernard; Appelshaeuser, Harald; Arcelli, Silvia; Armesto Perez, Nestor; Arnaldi, Roberta; Aronsson, Tomas; Arsene, Ionut Cristian; Arslandok, Mesut; Augustinus, Andre; Averbeck, Ralf Peter; Azmi, Mohd Danish; Bach, Matthias Jakob; Badala, Angela; Baek, Yong Wook; Bagnasco, Stefano; Bailhache, Raphaelle Marie; Bala, Renu; Baldisseri, Alberto; Ball, Markus; Baltasar Dos Santos Pedrosa, Fernando; Baral, Rama Chandra; Barbano, Anastasia Maria; Barbera, Roberto; Barile, Francesco; Barnafoldi, Gergely Gabor; Barnby, Lee Stuart; Ramillien Barret, Valerie; Bartalini, Paolo; Bartke, Jerzy Gustaw; Bartsch, Esther; Basile, Maurizio; Bastid, Nicole; Basu, Sumit; Bathen, Bastian; Batigne, Guillaume; Batista Camejo, Arianna; Batyunya, Boris; Batzing, Paul Christoph; Bearden, Ian Gardner; Beck, Hans; Bedda, Cristina; Behera, Nirbhay Kumar; Belikov, Iouri; Bellini, Francesca; Bello Martinez, Hector; Bellwied, Rene; Belmont Iii, Ronald John; Belmont Moreno, Ernesto; Belyaev, Vladimir; Bencedi, Gyula; Beole, Stefania; Berceanu, Ionela; Bercuci, Alexandru; Berdnikov, Yaroslav; Berenyi, Daniel; Bertens, Redmer Alexander; Berzano, Dario; Betev, Latchezar; Bhasin, Anju; Bhat, Inayat Rasool; Bhati, Ashok Kumar; Bhattacharjee, Buddhadeb; Bhom, Jihyun; Bianchi, Livio; Bianchi, Nicola; Bianchin, Chiara; Bielcik, Jaroslav; Bielcikova, Jana; Bilandzic, Ante; Biswas, Saikat; Bjelogrlic, Sandro; Blanco, Fernando; Blau, Dmitry; Blume, Christoph; Bock, Friederike; Bogdanov, Alexey; Boggild, Hans; Boldizsar, Laszlo; Bombara, Marek; Book, Julian Heinz; Borel, Herve; Borissov, Alexander; Borri, Marcello; Bossu, Francesco; Botje, Michiel; Botta, Elena; Boettger, Stefan; Braun-Munzinger, Peter; Bregant, Marco; Breitner, Timo Gunther; Broker, Theo Alexander; Browning, Tyler Allen; Broz, Michal; Brucken, Erik Jens; Bruna, Elena; Bruno, Giuseppe Eugenio; Budnikov, Dmitry; Buesching, Henner; Bufalino, Stefania; Buncic, Predrag; Busch, Oliver; Buthelezi, Edith Zinhle; Buxton, Jesse Thomas; Caffarri, Davide; Cai, Xu; Caines, Helen Louise; Calero Diaz, Liliet; Caliva, Alberto; Calvo Villar, Ernesto; Camerini, Paolo; Carena, Francesco; Carena, Wisla; Castillo Castellanos, Javier Ernesto; Castro, Andrew John; Casula, Ester Anna Rita; Cavicchioli, Costanza; Ceballos Sanchez, Cesar; Cepila, Jan; Cerello, Piergiorgio; Chang, Beomsu; Chapeland, Sylvain; Chartier, Marielle; Charvet, Jean-Luc Fernand; Chattopadhyay, Subhasis; Chattopadhyay, Sukalyan; Chelnokov, Volodymyr; Cherney, Michael Gerard; Cheshkov, Cvetan Valeriev; Cheynis, Brigitte; Chibante Barroso, Vasco Miguel; Dobrigkeit Chinellato, David; Chochula, Peter; Choi, Kyungeon; Chojnacki, Marek; Choudhury, Subikash; Christakoglou, Panagiotis; Christensen, Christian Holm; Christiansen, Peter; Chujo, Tatsuya; Chung, Suh-Urk; Cicalo, Corrado; Cifarelli, Luisa; Cindolo, Federico; Cleymans, Jean Willy Andre; Colamaria, Fabio Filippo; Colella, Domenico; Collu, Alberto; Colocci, Manuel; Conesa Balbastre, Gustavo; Conesa Del Valle, Zaida; Connors, Megan Elizabeth; Contreras Nuno, Jesus Guillermo; Cormier, Thomas Michael; Corrales Morales, Yasser; Cortes Maldonado, Ismael; Cortese, Pietro; Cosentino, Mauro Rogerio; Costa, Filippo; Crochet, Philippe; Cruz Albino, Rigoberto; Cuautle Flores, Eleazar; Cunqueiro Mendez, Leticia; Dahms, Torsten; Dainese, Andrea; Danu, Andrea; Das, Debasish; Das, Indranil; Das, Supriya; Dash, Ajay Kumar; Dash, Sadhana; De, Sudipan; De Caro, Annalisa; De Cataldo, Giacinto; De Cuveland, Jan; De Falco, Alessandro; De Gruttola, Daniele; De Marco, Nora; De Pasquale, Salvatore; Deisting, Alexander; Deloff, Andrzej; Denes, Ervin Sandor; D'Erasmo, Ginevra; Di Bari, Domenico; Di Mauro, Antonio; Di Nezza, Pasquale; Diaz Corchero, Miguel Angel; Dietel, Thomas; Dillenseger, Pascal; Divia, Roberto; Djuvsland, Oeystein; Dobrin, Alexandru Florin; Dobrowolski, Tadeusz Antoni; Domenicis Gimenez, Diogenes; Donigus, Benjamin; Dordic, Olja; Dubey, Anand Kumar; Dubla, Andrea; Ducroux, Laurent; Dupieux, Pascal; Ehlers Iii, Raymond James; Elia, Domenico; Engel, Heiko; Erazmus, Barbara Ewa; Erhardt, Filip; Eschweiler, Dominic; Espagnon, Bruno; Estienne, Magali Danielle; Esumi, Shinichi; Evans, David; Evdokimov, Sergey; Eyyubova, Gyulnara; Fabbietti, Laura; Fabris, Daniela; Faivre, Julien; Fantoni, Alessandra; Fasel, Markus; Feldkamp, Linus; Felea, Daniel; Feliciello, Alessandro; Feofilov, Grigorii; Ferencei, Jozef; Fernandez Tellez, Arturo; Gonzalez Ferreiro, Elena; Ferretti, Alessandro; Festanti, Andrea; Figiel, Jan; Araujo Silva Figueredo, Marcel; Filchagin, Sergey; Finogeev, Dmitry; Fionda, Fiorella; Fiore, Enrichetta Maria; Fleck, Martin Gabriel; Floris, Michele; Foertsch, Siegfried Valentin; Foka, Panagiota; Fokin, Sergey; Fragiacomo, Enrico; Francescon, Andrea; Frankenfeld, Ulrich Michael; Fuchs, Ulrich; Furget, Christophe; Furs, Artur; Fusco Girard, Mario; Gaardhoeje, Jens Joergen; Gagliardi, Martino; Gago Medina, Alberto Martin; Gallio, Mauro; Gangadharan, Dhevan Raja; Ganoti, Paraskevi; Gao, Chaosong; Garabatos Cuadrado, Jose; Garcia-Solis, Edmundo Javier; Gargiulo, Corrado; Gasik, Piotr Jan; Germain, Marie; Gheata, Andrei George; Gheata, Mihaela; Ghosh, Premomoy; Ghosh, Sanjay Kumar; Gianotti, Paola; Giubellino, Paolo; Giubilato, Piero; Gladysz-Dziadus, Ewa; Glassel, Peter; Gomez Ramirez, Andres; Gonzalez Zamora, Pedro; Gorbunov, Sergey; Gorlich, Lidia Maria; Gotovac, Sven; Grabski, Varlen; Graczykowski, Lukasz Kamil; Grelli, Alessandro; Grigoras, Alina Gabriela; Grigoras, Costin; Grigoryev, Vladislav; Grigoryan, Ara; Grigoryan, Smbat; Grynyov, Borys; Grion, Nevio; Grosse-Oetringhaus, Jan Fiete; Grossiord, Jean-Yves; Grosso, Raffaele; Guber, Fedor; Guernane, Rachid; Guerzoni, Barbara; Gulbrandsen, Kristjan Herlache; Gulkanyan, Hrant; Gunji, Taku; Gupta, Anik; Gupta, Ramni; Haake, Rudiger; Haaland, Oystein Senneset; Hadjidakis, Cynthia Marie; Haiduc, Maria; Hamagaki, Hideki; Hamar, Gergoe; Hanratty, Luke David; Hansen, Alexander; Harris, John William; Hartmann, Helvi; Harton, Austin Vincent; Hatzifotiadou, Despina; Hayashi, Shinichi; Heckel, Stefan Thomas; Heide, Markus Ansgar; Helstrup, Haavard; Herghelegiu, Andrei Ionut; Herrera Corral, Gerardo Antonio; Hess, Benjamin Andreas; Hetland, Kristin Fanebust; Hilden, Timo Eero; Hillemanns, Hartmut; Hippolyte, Boris; Hristov, Peter Zahariev; Huang, Meidana; Humanic, Thomas; Hussain, Nur; Hussain, Tahir; Hutter, Dirk; Hwang, Dae Sung; Ilkaev, Radiy; Ilkiv, Iryna; Inaba, Motoi; Ionita, Costin; Ippolitov, Mikhail; Irfan, Muhammad; Ivanov, Marian; Ivanov, Vladimir; Izucheev, Vladimir; Jacobs, Peter Martin; Jahnke, Cristiane; Jang, Haeng Jin; Janik, Malgorzata Anna; Pahula Hewage, Sandun; Jena, Chitrasen; Jena, Satyajit; Jimenez Bustamante, Raul Tonatiuh; Jones, Peter Graham; Jung, Hyungtaik; Jusko, Anton; Kalinak, Peter; Kalweit, Alexander Philipp; Kamin, Jason Adrian; Kang, Ju Hwan; Kaplin, Vladimir; Kar, Somnath; Karasu Uysal, Ayben; Karavichev, Oleg; Karavicheva, Tatiana; Karpechev, Evgeny; Kebschull, Udo Wolfgang; Keidel, Ralf; Keijdener, Darius Laurens; Keil, Markus; Khan, Kamal; Khan, Mohammed Mohisin; Khan, Palash; Khan, Shuaib Ahmad; Khanzadeev, Alexei; Kharlov, Yury; Kileng, Bjarte; Kim, Beomkyu; Kim, Do Won; Kim, Dong Jo; Kim, Hyeonjoong; Kim, Jinsook; Kim, Mimae; Kim, Minwoo; Kim, Se Yong; Kim, Taesoo; Kirsch, Stefan; Kisel, Ivan; Kiselev, Sergey; Kisiel, Adam Ryszard; Kiss, Gabor; Klay, Jennifer Lynn; Klein, Carsten; Klein, Jochen; Klein-Boesing, Christian; Kluge, Alexander; Knichel, Michael Linus; Knospe, Anders Garritt; Kobayashi, Taiyo; Kobdaj, Chinorat; Kofarago, Monika; Kohler, Markus Konrad; Kollegger, Thorsten; Kolozhvari, Anatoly; Kondratev, Valerii; Kondratyeva, Natalia; Kondratyuk, Evgeny; Konevskikh, Artem; Kouzinopoulos, Charalampos; Kovalenko, Vladimir; Kowalski, Marek; Kox, Serge; Koyithatta Meethaleveedu, Greeshma; Kral, Jiri; Kralik, Ivan; Kravcakova, Adela; Krelina, Michal; Kretz, Matthias; Krivda, Marian; Krizek, Filip; Kryshen, Evgeny; Krzewicki, Mikolaj; Kubera, Andrew Michael; Kucera, Vit; Kucheryaev, Yury; Kugathasan, Thanushan; Kuhn, Christian Claude; Kuijer, Paulus Gerardus; Kulakov, Igor; Kumar, Jitendra; Lokesh, Kumar; Kurashvili, Podist; Kurepin, Alexander; Kurepin, Alexey; Kuryakin, Alexey; Kushpil, Svetlana; Kweon, Min Jung; Kwon, Youngil; La Pointe, Sarah Louise; La Rocca, Paola; Lagana Fernandes, Caio; Lakomov, Igor; Langoy, Rune; Lara Martinez, Camilo Ernesto; Lardeux, Antoine Xavier; Lattuca, Alessandra; Laudi, Elisa; Lea, Ramona; Leardini, Lucia; Lee, Graham Richard; Lee, Seongjoo; Legrand, Iosif; Lehnert, Joerg Walter; Lemmon, Roy Crawford; Lenti, Vito; Leogrande, Emilia; Leon Monzon, Ildefonso; Leoncino, Marco; Levai, Peter; Li, Shuang; Li, Xiaomei; Lien, Jorgen Andre; Lietava, Roman; Lindal, Svein; Lindenstruth, Volker; Lippmann, Christian; Lisa, Michael Annan; Ljunggren, Hans Martin; Lodato, Davide Francesco; Lonne, Per-Ivar; Loggins, Vera Renee; Loginov, Vitaly; Loizides, Constantinos; Lopez, Xavier Bernard; Lopez Torres, Ernesto; Lowe, Andrew John; Lu, Xianguo; Luettig, Philipp Johannes; Lunardon, Marcello; Luparello, Grazia; Maevskaya, Alla; Mager, Magnus; Mahajan, Sanjay; Mahmood, Sohail Musa; Maire, Antonin; Majka, Richard Daniel; Malaev, Mikhail; Maldonado Cervantes, Ivonne Alicia; Malinina, Liudmila; Mal'Kevich, Dmitry; Malzacher, Peter; Mamonov, Alexander; Manceau, Loic Henri Antoine; Manko, Vladislav; Manso, Franck; Manzari, Vito; Marchisone, Massimiliano; Mares, Jiri; Margagliotti, Giacomo Vito; Margotti, Anselmo; Margutti, Jacopo; Marin, Ana Maria; Markert, Christina; Marquard, Marco; Martashvili, Irakli; Martin, Nicole Alice; Martin Blanco, Javier; Martinengo, Paolo; Martinez Hernandez, Mario Ivan; Martinez-Garcia, Gines; Martinez Pedreira, Miguel; Martynov, Yevgen; Mas, Alexis Jean-Michel; Masciocchi, Silvia; Masera, Massimo; Masoni, Alberto; Massacrier, Laure Marie; Mastroserio, Annalisa; Matyja, Adam Tomasz; Mayer, Christoph; Mazer, Joel Anthony; Mazzoni, Alessandra Maria; Mcdonald, Daniel; Meddi, Franco; Menchaca-Rocha, Arturo Alejandro; Meninno, Elisa; Mercado-Perez, Jorge; Meres, Michal; Miake, Yasuo; Mieskolainen, Matti Mikael; Mikhaylov, Konstantin; Milano, Leonardo; Milosevic, Jovan; Minervini, Lazzaro Manlio; Mischke, Andre; Mishra, Aditya Nath; Miskowiec, Dariusz Czeslaw; Mitra, Jubin; Mitu, Ciprian Mihai; Mohammadi, Naghmeh; Mohanty, Bedangadas; Molnar, Levente; Montano Zetina, Luis Manuel; Montes Prado, Esther; Morando, Maurizio; Moreira De Godoy, Denise Aparecida; Moretto, Sandra; Morreale, Astrid; Morsch, Andreas; Muccifora, Valeria; Mudnic, Eugen; Muhlheim, Daniel Michael; Muhuri, Sanjib; Mukherjee, Maitreyee; Muller, Hans; Mulligan, James Declan; Gameiro Munhoz, Marcelo; Murray, Sean; Musa, Luciano; Musinsky, Jan; Nandi, Basanta Kumar; Nania, Rosario; Nappi, Eugenio; Naru, Muhammad Umair; Nattrass, Christine; Nayak, Kishora; Nayak, Tapan Kumar; Nazarenko, Sergey; Nedosekin, Alexander; Nellen, Lukas; Ng, Fabian; Nicassio, Maria; Niculescu, Mihai; Niedziela, Jeremi; Nielsen, Borge Svane; Nikolaev, Sergey; Nikulin, Sergey; Nikulin, Vladimir; Noferini, Francesco; Nomokonov, Petr; Nooren, Gerardus; Norman, Jaime; Nyanin, Alexander; Nystrand, Joakim Ingemar; Oeschler, Helmut Oskar; Oh, Saehanseul; Oh, Sun Kun; Ohlson, Alice Elisabeth; Okatan, Ali; Okubo, Tsubasa; Olah, Laszlo; Oleniacz, Janusz; Oliveira Da Silva, Antonio Carlos; Oliver, Michael Henry; Onderwaater, Jacobus; Oppedisano, Chiara; Ortiz Velasquez, Antonio; Oskarsson, Anders Nils Erik; Otwinowski, Jacek Tomasz; Oyama, Ken; Ozdemir, Mahmut; Pachmayer, Yvonne Chiara; Pagano, Paola; Paic, Guy; Pajares Vales, Carlos; Pal, Susanta Kumar; Pan, Jinjin; Pandey, Ashutosh Kumar; Pant, Divyash; Papikyan, Vardanush; Pappalardo, Giuseppe; Pareek, Pooja; Park, Woojin; Parmar, Sonia; Passfeld, Annika; Paticchio, Vincenzo; Paul, Biswarup; Pawlak, Tomasz Jan; Peitzmann, Thomas; Pereira Da Costa, Hugo Denis Antonio; Pereira De Oliveira Filho, Elienos; Peresunko, Dmitry Yurevich; Perez Lara, Carlos Eugenio; Peskov, Vladimir; Pestov, Yury; Petracek, Vojtech; Petrov, Viacheslav; Petrovici, Mihai; Petta, Catia; Piano, Stefano; Pikna, Miroslav; Pillot, Philippe; Pinazza, Ombretta; Pinsky, Lawrence; Piyarathna, Danthasinghe; Ploskon, Mateusz Andrzej; Planinic, Mirko; Pluta, Jan Marian; Pochybova, Sona; Podesta Lerma, Pedro Luis Manuel; Poghosyan, Martin; Polishchuk, Boris; Poljak, Nikola; Poonsawat, Wanchaloem; Pop, Amalia; Porteboeuf, Sarah Julie; Porter, R Jefferson; Pospisil, Jan; Prasad, Sidharth Kumar; Preghenella, Roberto; Prino, Francesco; Pruneau, Claude Andre; Pshenichnov, Igor; Puccio, Maximiliano; Puddu, Giovanna; Pujahari, Prabhat Ranjan; Punin, Valery; Putschke, Jorn Henning; Qvigstad, Henrik; Rachevski, Alexandre; Raha, Sibaji; Rajput, Sonia; Rak, Jan; Rakotozafindrabe, Andry Malala; Ramello, Luciano; Raniwala, Rashmi; Raniwala, Sudhir; Rasanen, Sami Sakari; Rascanu, Bogdan Theodor; Rathee, Deepika; Razazi, Vahedeh; Read, Kenneth Francis; Real, Jean-Sebastien; Redlich, Krzysztof; Reed, Rosi Jan; Rehman, Attiq Ur; Reichelt, Patrick Simon; Reicher, Martijn; Reidt, Felix; Ren, Xiaowen; Renfordt, Rainer Arno Ernst; Reolon, Anna Rita; Reshetin, Andrey; Rettig, Felix Vincenz; Revol, Jean-Pierre; Reygers, Klaus Johannes; Riabov, Viktor; Ricci, Renato Angelo; Richert, Tuva Ora Herenui; Richter, Matthias Rudolph; Riedler, Petra; Riegler, Werner; Riggi, Francesco; Ristea, Catalin-Lucian; Rivetti, Angelo; Rocco, Elena; Rodriguez Cahuantzi, Mario; Rodriguez Manso, Alis; Roeed, Ketil; Rogochaya, Elena; Rohr, David Michael; Roehrich, Dieter; Romita, Rosa; Ronchetti, Federico; Ronflette, Lucile; Rosnet, Philippe; Rossi, Andrea; Roukoutakis, Filimon; Roy, Ankhi; Roy, Christelle Sophie; Roy, Pradip Kumar; Rubio Montero, Antonio Juan; Rui, Rinaldo; Russo, Riccardo; Ryabinkin, Evgeny; Ryabov, Yury; Rybicki, Andrzej; Sadovskiy, Sergey; Safarik, Karel; Sahlmuller, Baldo; Sahoo, Pragati; Sahoo, Raghunath; Sahoo, Sarita; Sahu, Pradip Kumar; Saini, Jogender; Sakai, Shingo; Saleh, Mohammad Ahmad; Salgado Lopez, Carlos Alberto; Salzwedel, Jai Samuel Nielsen; Sambyal, Sanjeev Singh; Samsonov, Vladimir; Sanchez Castro, Xitzel; Sandor, Ladislav; Sandoval, Andres; Sano, Masato; Santagati, Gianluca; Sarkar, Debojit; Scapparone, Eugenio; Scarlassara, Fernando; Scharenberg, Rolf Paul; Schiaua, Claudiu Cornel; Schicker, Rainer Martin; Schmidt, Christian Joachim; Schmidt, Hans Rudolf; Schuchmann, Simone; Schukraft, Jurgen; Schulc, Martin; Schuster, Tim Robin; Schutz, Yves Roland; Schwarz, Kilian Eberhard; Schweda, Kai Oliver; Scioli, Gilda; Scomparin, Enrico; Scott, Rebecca Michelle; Seeder, Karin Soraya; Seger, Janet Elizabeth; Sekiguchi, Yuko; Selyuzhenkov, Ilya; Senosi, Kgotlaesele; Seo, Jeewon; Serradilla Rodriguez, Eulogio; Sevcenco, Adrian; Shabanov, Arseniy; Shabetai, Alexandre; Shadura, Oksana; Shahoyan, Ruben; Shangaraev, Artem; Sharma, Ankita; Sharma, Natasha; Shigaki, Kenta; Shtejer Diaz, Katherin; Sibiryak, Yury; Siddhanta, Sabyasachi; Sielewicz, Krzysztof Marek; Siemiarczuk, Teodor; Silvermyr, David Olle Rickard; Silvestre, Catherine Micaela; Simatovic, Goran; Simonetti, Giuseppe; Singaraju, Rama Narayana; Singh, Ranbir; Singha, Subhash; Singhal, Vikas; Sinha, Bikash; Sarkar - Sinha, Tinku; Sitar, Branislav; Sitta, Mario; Skaali, Bernhard; Slupecki, Maciej; Smirnov, Nikolai; Snellings, Raimond; Snellman, Tomas Wilhelm; Soegaard, Carsten; Soltz, Ron Ariel; Song, Jihye; Song, Myunggeun; Song, Zixuan; Soramel, Francesca; Sorensen, Soren Pontoppidan; Spacek, Michal; Spiriti, Eleuterio; Sputowska, Iwona Anna; Spyropoulou-Stassinaki, Martha; Srivastava, Brijesh Kumar; Stachel, Johanna; Stan, Ionel; Stefanek, Grzegorz; Steinpreis, Matthew Donald; Stenlund, Evert Anders; Steyn, Gideon Francois; Stiller, Johannes Hendrik; Stocco, Diego; Strmen, Peter; Alarcon Do Passo Suaide, Alexandre; Sugitate, Toru; Suire, Christophe Pierre; Suleymanov, Mais Kazim Oglu; Sultanov, Rishat; Sumbera, Michal; Symons, Timothy; Szabo, Alexander; Szanto De Toledo, Alejandro; Szarka, Imrich; Szczepankiewicz, Adam; Szymanski, Maciej Pawel; Takahashi, Jun; Tanaka, Naoto; Tangaro, Marco-Antonio; Tapia Takaki, Daniel Jesus; Tarantola Peloni, Attilio; Tariq, Mohammad; Tarzila, Madalina-Gabriela; Tauro, Arturo; Tejeda Munoz, Guillermo; Telesca, Adriana; Terasaki, Kohei; Terrevoli, Cristina; Teyssier, Boris; Thaeder, Jochen Mathias; Thomas, Deepa; Tieulent, Raphael Noel; Timmins, Anthony Robert; Toia, Alberica; Trogolo, Stefano; Trubnikov, Victor; Trzaska, Wladyslaw Henryk; Tsuji, Tomoya; Tumkin, Alexandr; Turrisi, Rosario; Tveter, Trine Spedstad; Ullaland, Kjetil; Uras, Antonio; Usai, Gianluca; Utrobicic, Antonija; Vajzer, Michal; Vala, Martin; Valencia Palomo, Lizardo; Vallero, Sara; Van Der Maarel, Jasper; Van Hoorne, Jacobus Willem; Van Leeuwen, Marco; Vanat, Tomas; Vande Vyvre, Pierre; Varga, Dezso; Vargas Trevino, Aurora Diozcora; Vargyas, Marton; Varma, Raghava; Vasileiou, Maria; Vasiliev, Andrey; Vauthier, Astrid; Vechernin, Vladimir; Veen, Annelies Marianne; Veldhoen, Misha; Velure, Arild; Venaruzzo, Massimo; Vercellin, Ermanno; Vergara Limon, Sergio; Vernet, Renaud; Verweij, Marta; Vickovic, Linda; Viesti, Giuseppe; Viinikainen, Jussi Samuli; Vilakazi, Zabulon; Villalobos Baillie, Orlando; Vinogradov, Alexander; Vinogradov, Leonid; Vinogradov, Yury; Virgili, Tiziano; Vislavicius, Vytautas; Viyogi, Yogendra; Vodopyanov, Alexander; Volkl, Martin Andreas; Voloshin, Kirill; Voloshin, Sergey; Volpe, Giacomo; Von Haller, Barthelemy; Vorobyev, Ivan; Vranic, Danilo; Vrlakova, Janka; Vulpescu, Bogdan; Vyushin, Alexey; Wagner, Boris; Wagner, Jan; Wang, Hongkai; Wang, Mengliang; Wang, Yifei; Watanabe, Daisuke; Weber, Michael; Weber, Steffen Georg; Wessels, Johannes Peter; Westerhoff, Uwe; Wiechula, Jens; Wikne, Jon; Wilde, Martin Rudolf; Wilk, Grzegorz Andrzej; Wilkinson, Jeremy John; Williams, Crispin; Windelband, Bernd Stefan; Winn, Michael Andreas; Yaldo, Chris G; Yamaguchi, Yorito; Yang, Hongyan; Yang, Ping; Yano, Satoshi; Yasnopolskiy, Stanislav; Yin, Zhongbao; Yokoyama, Hiroki; Yoo, In-Kwon; Yurchenko, Volodymyr; Yushmanov, Igor; Zaborowska, Anna; Zaccolo, Valentina; Zaman, Ali; Zampolli, Chiara; Correia Zanoli, Henrique Jose; Zaporozhets, Sergey; Zarochentsev, Andrey; Zavada, Petr; Zavyalov, Nikolay; Zbroszczyk, Hanna Paulina; Zgura, Sorin Ion; Zhalov, Mikhail; Zhang, Haitao; Zhang, Xiaoming; Zhang, Yonghong; Zhao, Chengxin; Zhigareva, Natalia; Zhou, Daicui; Zhou, You; Zhou, Zhuo; Zhu, Hongsheng; Zhu, Jianhui; Zhu, Xiangrong; Zichichi, Antonino; Zimmermann, Alice; Zimmermann, Markus Bernhard; Zinovjev, Gennady; Zyzak, Maksym

    2015-01-01

    The measurement of the mass differences for systems bound by the strong force has reached a very high precision with protons and anti-protons. The extension of such measurement from (anti-)baryons to (anti-)nuclei allows one to probe any difference in the interactions between nucleons and anti-nucleons encoded in the (anti-)nuclei masses. This force is a remnant of the underlying strong interaction among quarks and gluons and can be described by effective theories, but cannot yet be directly derived from quantum chromodynamics. Here we report a measurement of the difference between the ratios of the mass and charge of deuterons (d) and anti-deuterons ($\\bar{d}$), and $^{3}{\\rm He}$ and $^3\\overline{\\rm He}$ nuclei carried out with the ALICE (A Large Ion Collider Experiment) detector in Pb-Pb collisions at a centre-of-mass energy per nucleon pair of 2.76 TeV. Our direct measurement of the mass-over-charge differences confirm CPT invariance to an unprecedented precision in the sector of light nuclei. This funda...

  3. Exotic modes of excitation in atomic nuclei far from stability

    OpenAIRE

    Paar, N.; Vretenar, D.; Khan, E.; Colo, G.

    2007-01-01

    We review recent studies of the evolution of collective excitations in atomic nuclei far from the valley of $\\beta$-stability. Collective degrees of freedom govern essential aspects of nuclear structure, and for several decades the study of collective modes such as rotations and vibrations has played a vital role in our understanding of complex properties of nuclei. The multipole response of unstable nuclei and the possible occurrence of new exotic modes of excitation in weakly-bound nuclear ...

  4. Structure of collective modes in transitional and deformed nuclei

    OpenAIRE

    Caprio, M. A.

    2005-01-01

    The collective structure of atomic nuclei intermediate between spherical and quadrupole deformed structure presents challenges to theoretical understanding. However, models have recently been proposed in terms of potentials which are soft with respect to the quadrupole deformation variable beta. To test these models, information is needed on low-spin states of transitional nuclei. The present work involves measurement of electromagnetic decay properties of low-spin states for nuclei in the A=...

  5. Collisions of Small Nuclei in the Thermal Model

    CERN Document Server

    Cleymans, J; Oeschler, H; Redlich, K; Sharma, N

    2016-01-01

    An analysis is presented of the expectations of the thermal model for particle production in collisions of small nuclei. The maxima observed in particle ratios of strange particles to pions as a function of beam energy in heavy ion collisions, are reduced when considering smaller nuclei. Of particular interest is the $\\Lambda/\\pi^+$ ratio shows the strongest maximum which survives even in collisions of small nuclei.

  6. Systematics of light nuclei in a relativistic model

    International Nuclear Information System (INIS)

    The results of relativistic mean field calculations for non-spherical nuclei are presented and discussed. The need for non-linear scalar meson self-couplings in order to describe the properties of s-d shell nuclei is emphasized along with the importance of self-consistency in calculations of magnetic moments of odd-mass nuclei. 16 refs., 3 figs., 2 tabs

  7. Production of light nuclei in the thermal and coalescence models

    CERN Document Server

    Mrowczynski, Stanislaw

    2016-01-01

    The thermal model properly describes the yield of light nuclei in relativistic heavy-ion collisions even so the loosely bound sizable nuclei cannot exist in the dense and hot hadron gas. Within the coalescence model, light nuclei are formed at the latest stage of nuclear collisions due to final state interactions. After discussing the models, we derive simple analytic formulas showing that the thermal and coalescence model predictions are quantitatively close to each other.

  8. AMD study of cluster structures in light nuclei

    International Nuclear Information System (INIS)

    We review the AMD study of cluster structures in stable and unstable light nuclei. We place emphasis on the characteristic features of the AMD approach, which include variation after parity projection, three-dimensional cranking and variation after angular momentum projection, superposition of Slater determinants for the study of excited states, and unified treatment of structure and reaction calculations. We discuss the novel features of clustering in neutron-rich nuclei in comparison with clustering in stable nuclei. (author)

  9. PROJECTIONS OF DORSAL AND MEDIAN RAPHE NUCLEI TO DORSAL AND VENTRAL STRIATUM

    Directory of Open Access Journals (Sweden)

    G. R. Hassanzadeh G. Behzadi

    2007-08-01

    Full Text Available The ascending serotonergic projections are derived mainly from mesencephalic raphe nuclei. Topographical projections from mesencephalic raphe nuclei to the striatum were examined in the rat by the retrograde transport technique of HRP (horseradish peroxidase. In 29 rats stereotaxically injection of HRP enzyme were performed in dorsal and ventral parts of striatum separately. The extent of the injection sites and distribution of retrogradely labeled neuronal cell bodies were drawed on representative sections using a projection microscope. Following ipsilateral injection of HRP into the dorsal striatum, numerous labeled neurons were seen in rostral portion of dorsal raphe (DR nucleus. In the same level the cluster of labeled neurons were hevier through caudal parts of DR. A few neurons were also located in lateral wing of DR. More caudally some labeled neurons were found in lateral, medial line of DR. In median raphe nucleus (MnR the labeled neurons were scattered only in median portion of this nucleus. The ipsilateral injection of HRP into the ventral region of striatum resulted on labeling of numerous neurons in rostral, caudal and lateral portions of DR. Through the caudal extension of DR on 4th ventricle level, a large number of labeled neurons were distributed along the ventrocaudal parts of DR. In MnR, labeled neurons were observed only in median part of this nucleus. These findings suggest the mesencephalic raphe nuclei projections to caudo-putamen are topographically organized. In addition dorsal and median raphe nuclei have a stronger projection to the ventral striatum.

  10. Shape coexistence and triaxiality in nuclei near 80Zr

    CERN Document Server

    Zheng, S J; Shen, S F; Liu, H L; Wyss, R

    2013-01-01

    Total-Routhian-Surface calculations have been performed to investigate the shape evolutions of $A\\sim80$ nuclei, $^{80-84}$Zr, $^{76-80}$Sr and $^{84,86}$Mo. Shape coexistences of spherical, prolate and oblate deformations have been found in these nuclei. Particularly for the nuclei, $^{80}$Sr and $^{82}$Zr, the energy differences between two shape-coexisting states are less than 220 keV. At high spins, the $g_{9/2}$ shell plays an important role for shape evolutions. It has been found that the alignment of the $g_{9/2}$ quasi-particles drives nuclei to be triaxial.

  11. The synthesis structure and decay of super-heavy nuclei

    International Nuclear Information System (INIS)

    Super-heavy nuclei are those transuranic nuclei with more than 106 protons . The underlying nuclear structure of super-heavy elements may be visualized as 5 concentric closed layers of alpha particles. This structure is an extension of layered alpha particle models of common nuclei based on Bernal's model of a drop of a monatomic liquid. It will be shown mat all super-heavy nuclei with atomic numbers in excess of 107 may be thought of as having a fifth closed layer of 16 alpha particles which decays because of its inherent instability

  12. Study of nuclear level densities for exotic nuclei

    Directory of Open Access Journals (Sweden)

    M Nasri Nasrabadi

    2012-06-01

    Full Text Available Nuclear level density (NLD is one of the properties of nuclei with widespread applications in astrophysics and nuclear medicine. Since there has been little experimental and theoretical research on the study of nuclei which are far from stability line, studying NLD for these nuclei is of crucial importance. Also, as NLD is an important input for nuclear research codes, hence studying the methods for calculation of this parameter is essential. Besides introducing various methods and models for calculating NLD for practical applications, we used exact spectra distribution (SPDM for determining NLD of two neutron and proton enriched exotic nuclei with the same mass number.

  13. Unique features of transuranic odd-odd nuclei

    International Nuclear Information System (INIS)

    Odd-odd nuclei in the transuranic region have significantly longer half-lives than their odd-mass core nuclei. Further, the occurrence of long-lived isomers is a quite common feature in these nuclei. Interestingly in almost all the known isomer pairs, the ambiguity in the relative energy placement of the two isomers does not enable to know which of the two isomers is the real ground state. This is due to the fact that due to large difference in isomer spins, the two do not connect through an isomeric transition (IT). In this report these properties are illustrated by discussing the Z=99 Einsteinium sequence of nuclei

  14. Energy loss and critical energies of ultrarelativistic nuclei

    International Nuclear Information System (INIS)

    The energy loss and critical energies of ultrarelativistic nuclei are calculated with allowance for the fact that the dominant radiation process for the nuclei is the formation of e+e- pairs. It is shown that in the region of superhigh energies the total average ionization loss of the nuclei (hadrons) reaches a plateau dependent on the type of nucleus (hadron) and on the characteristics of the medium. Special features of the energy spectra of e+e- pairs and δ electrons formed by the nuclei are analyzed

  15. Relativistic mean field study of clustering in nuclei

    International Nuclear Information System (INIS)

    Clustering phenomenon in exotic, light, heavy and superheavy nuclei is studied within the relativistic mean field (RMF) approach. Numerical calculations are done by using the axially deformed harmonic oscillator basis. The calculated nucleon density distributions and deformation parameters are analyzed to look for the cluster configurations. In case of light nuclei, the calculations explain many of the well established cluster structures in both the ground and intrinsic excited states. In the heavy and superheavy nuclei, interesting results are obtained and the results indicate new possibilities of exotic clusters at the centre of superheavy nuclei. (author)

  16. Spectroscopy of very heavy nuclei with a view to study super-heavy nuclei

    International Nuclear Information System (INIS)

    Within the recent years, the spectroscopic study of single particle orbitals of very heavy elements (VHE) has become possible with the development of increasingly efficient experimental setups. This allows us, through nuclear deformation, to access with these deformed nuclei to orbitals situated around the Fermi level in the spherical superheavy elements (SHE) and learn more about the nuclear structure of these nuclei. The aim of this work is the spectroscopic studies of heavy and very heavy elements. Because of the experimental difficulties associated with the fusion reactions in the VHE region, a detailed optimization studies is essential. Simulation of energy loss and angular straggling of these nuclei due to the interaction in the target and to neutron's evaporation was carried out and allowed us to optimize the angular acceptance of the separators according to the target thickness. An extensive survey and exploration in the VHE region was also conducted on the basis of cross section's systematics in the literature and simulations carried out using the statistical code Hivap. In this framework, the possible extension of the range of validity of a set of Hivap parameters was investigated. This work has enabled us to prepare a list of experiments of interest for the production of very heavy nuclei. In this thesis, our work was concentrated on the spectroscopy of the nuclei No256 et Rf256 for which two experimental proposals were accepted. The octupole deformations predicted in the actinides region is studied in another part of this thesis, a part witch is dedicated to the gamma spectroscopy of Pa223. The data from a new experiment carried out using the Jurogam-Ritu-Great setup are analysed and compared to previous results. They confirm the octupole deformed shape in this nucleus. (author)

  17. Halo Nuclei: Stepping Stones Across the Dripline

    International Nuclear Information System (INIS)

    The availability of intense secondary beams in conjunction with efficient detection setups allows for a production and study of the most extreme nuclear systems, in terms of asymmetry of proton and neutron number, in the continuum. They can be produced via transfer and knockout reactions, depending on beam energies, with beams of nuclei close to the driplines, exhibiting exotic properties themselves, as seeds. These nuclear open quantum systems far from the valley of beta stability challenge nuclear structure theory being as well as reaction theory that tries to describe their production mechanisms. Due to their strong clustering they exhibit a rather clean few-body character. From experiments momentum distributions, relative energy spectra, and spin alignment during the reaction can be determined, which leads to the observation of energy and angular correlations as well as dependent quantities like e.g. the profile function denoting a momentum width in dependence of relative energy. They are determined from momentum vectors of fragments and gamma radiation leaving the reaction zone. The link to intrinsic properties of these unbound systems has to be explored by gathering precise knowledge of the properties of the seed nuclei and compare them to the structures observed in the continuum. In this paper I will exemplify the above-mentioned methods, and apply them particularly to light systems like 10He, 10−13Li, and neutron-rich Beryllium systems. Furthermore, perspectives for the 7H and heavy Oxygen systems are discussed. (author)

  18. Charming Mesons with Baryons and Nuclei

    Science.gov (United States)

    Tolos, Laura

    2013-11-01

    The properties of charmed mesons in nuclear matter and nuclei are reviewed. Different frameworks are discussed paying a special attention to unitarized coupled-channel approaches which incorporate heavy-quark spin symmetry. Several charmed baryon states with negative parity are generated dynamically by the s-wave interaction between pseudoscalar and vector meson multiplets with 1/2+ and 3/2+ baryons. These states are compared to experimental data. Moreover, the properties of open-charm mesons in matter are analyzed. The in-medium solution accounts for Pauli blocking effects, and for the meson self-energies in a self-consistent manner. The behavior in the nuclear medium of the rich spectrum of dynamically-generated baryon states is studied as well as their influence in the self-energy and, hence, the spectral function of open charm. The possible experimental signatures of the in-medium properties of open charm are finally addressed, such as the formation of charmed nuclei, in connection with the future FAIR facility.

  19. Charming mesons with baryons and nuclei

    CERN Document Server

    Tolos, Laura

    2013-01-01

    The properties of charmed mesons in nuclear matter and nuclei are reviewed. Different frameworks are discussed paying a special attention to unitarized coupled-channel approaches which incorporate heavy-quark spin symmetry. Several charmed baryon states with negative parity are generated dynamically by the s-wave interaction between pseudoscalar and vector meson multiplets with $1/2^+$ and $3/2^+$ baryons. These states are compared to experimental data. Moreover, the properties of open-charm mesons in matter are analyzed. The in-medium solution accounts for Pauli blocking effects, and for the meson self-energies in a self-consistent manner. The behavior in the nuclear medium of the rich spectrum of dynamically-generated baryon states is studied as well as their influence in the self-energy and, hence, the spectral function of open charm. The possible experimental signatures of the in-medium properties of open charm are finally addressed, such as the formation of charmed nuclei, in connection with the future F...

  20. Stellar transits in active galactic nuclei

    CERN Document Server

    Béky, Bence

    2012-01-01

    Supermassive black holes (SMBH) are typically surrounded by a dense stellar population in galactic nuclei. Stars crossing the line of site in active galactic nuclei (AGN) produce a characteristic transit lightcurve, just like extrasolar planets do when they transit their host star. We examine the possibility of finding such AGN transits in deep optical, UV, and X-ray surveys. We calculate transit lightcurves using the Novikov--Thorne thin accretion disk model, including general relatistic effects. Based on the expected properties of stellar cusps, we find that around 10^6 solar mass SMBHs, transits of red giants are most common for stars on close orbits with transit durations of a few weeks and orbital periods of a few years. We find that detecting AGN transits requires repeated observations of thousands of low mass AGNs to 1% photometric accuracy in optical, or ~ 10% in UV bands or soft X-ray. It may be possible to identify stellar transits in the Pan-STARRS and LSST optical and the eROSITA X-ray surveys. Su...

  1. Stellar Transits in Active Galactic Nuclei

    Science.gov (United States)

    Béky, Bence; Kocsis, Bence

    2013-01-01

    Supermassive black holes (SMBHs) are typically surrounded by a dense stellar population in galactic nuclei. Stars crossing the line of site in active galactic nuclei (AGNs) produce a characteristic transit light curve, just like extrasolar planets do when they transit their host star. We examine the possibility of finding such AGN transits in deep optical, UV, and X-ray surveys. We calculate transit light curves using the Novikov-Thorne thin accretion disk model, including general relativistic effects. Based on the expected properties of stellar cusps, we find that around 106 solar mass SMBHs, transits of red giants are most common for stars on close orbits with transit durations of a few weeks and orbital periods of a few years. We find that detecting AGN transits requires repeated observations of thousands of low-mass AGNs to 1% photometric accuracy in optical, or ~10% in UV bands or soft X-ray. It may be possible to identify stellar transits in the Pan-STARRS and LSST optical and the eROSITA X-ray surveys. Such observations could be used to constrain black hole mass, spin, inclination, and accretion rate. Transit rates and durations could give valuable information on the circumnuclear stellar clusters as well. Transit light curves could be used to image accretion disks with unprecedented resolution, allowing us to resolve the SMBH silhouette in distant AGNs.

  2. Fast neutron scattering on actinide nuclei

    International Nuclear Information System (INIS)

    More and more sophisticated neutron experiments have been carried out with better samples in several laboratories and it was necessary to intercompare them. In this respect, let us quote for example (n,n'e) and (n,n'#betta#) measurements. Moreover, high precision (p,p), (p,p') and (p,n) measurements have been made, thus supplementing neutron experiments in the determination of the parameters of the optical model, still widely used to describe the neutron-nucleus interaction. The optical model plays a major role and it is therefore essential to know it well. The spherical optical model is still very useful, especially because of its simplicity and of the relatively short calculation times, but is obviously insufficient to treat deformed nuclei such as actinides. For accurate calculations about these nuclei, it is necessary to use a deformed potential well and solve a set of coupled equations, hence long computational times. The importance of compound nucleus formation at low energy requires also a good knowledge of the statistical model together with that of all the reaction mechanisms which are involved, including fission for which an accurate barrier is necessary and, of course, well-adjusted level densities. The considerations form the background of the Scientific Programme set up by a Programme Committee whose composition is given further on in this book

  3. Halo Nuclei: Stepping Stones Across the Dripline

    Science.gov (United States)

    Simon, Haik

    2013-08-01

    The availability of intense secondary beams in conjunction with efficient detection setups allows for a production and study of the most extreme nuclear systems, in terms of asymmetry of proton and neutron number, in the continuum. They can be produced via transfer and knockout reactions, depending on beam energies, with beams of nuclei close to the driplines, exhibiting exotic properties themselves, as seeds. These nuclear open quantum systems far from the valley of beta stability challenge nuclear structure theory being as well as reaction theory that tries to describe their production mechanisms. Due to their strong clustering they exhibit a rather clean few-body character. From experiments momentum distributions, relative energy spectra, and spin alignment during the reaction can be determined, which leads to the observation of energy and angular correlations as well as dependent quantities like e.g. the profile function denoting a momentum width in dependence of relative energy. They are determined from momentum vectors of fragments and gamma radiation leaving the reaction zone. The link to intrinsic properties of these unbound systems has to be explored by gathering precise knowledge of the properties of the seed nuclei and compare them to the structures observed in the continuum. In this paper I will exemplify the above-mentioned methods, and apply them particularly to light systems like 10He, 10-13Li, and neutron-rich Beryllium systems. Furthermore, perspectives for the 7H and heavy Oxygen systems are discussed.

  4. Birth, life and death of hot nuclei

    International Nuclear Information System (INIS)

    Intermediate energy heavy-ions (10-100 MeV/u) are the most powerful tool to study hot nuclear matter properties. In this paper we give a review of experimental and theoretical works which support this statement. The first challenge is to achieve hot nuclei formation. The second one is to study their properties. The formation step is governed by the relative influence of nucleon-nucleon collisions and mean field effects. Fundamental quantities such as excited matter decay time, thermalization time, relaxation time for collective modes are of major importance and are compared with typical collision times. It appears that semi-classical theories are able to give a reasonable description of the collision and that they are a good guide for defining further experiments. We show how it has been possible to experimentally establish that very hot equilibrated nuclei are really formed. Their decay properties are not basically different from decay properties at lower bombarding energy. However specific channels are open: in that sense, we take stock of the multifragmentation process. Moreover, compression effects may be an important feature of this energy range. Future studies will involve heavier projectiles around 30-50 MeV/u. They will be the best probe for hot and compressed nuclear matter studies

  5. Photoproduction of Mesons off Light Nuclei

    International Nuclear Information System (INIS)

    During the last few years, a series of experiments has been done at the ELSA accelerator in Bonn with the Crystal Barrel/TAPS setup and at the MAMI accelerator in Mainz with the Crystal Ball/TAPS setup. Photoproduction of light mesons off the deuteron and 3He-nuclei has been studied in detail. We will report some of the most interesting results.A completely unexpected finding, is the pronounced structure in the excitation function of the γn → nη reaction around 1 GeV, which has no counterpart for the proton. Recent measurements at GRAAL, Sendai, ELSA [1] and MAMI estimate it's width below 50 MeV, which would be extremely narrow for a nucleon resonance at this excitation energy. In the experiment with the 3He target, special attention was given to the threshold behavior of the γHe3 reactions in view of possible indications for the formation of (quasi-)bound η-nucleus states, so-called η-mesic nuclei. A very strong threshold enhancement of coherent η-photoproduction off 3He was found. In a new experiment, this reaction was measured with much better statistical accuracy compared to an earlier experiment at MAMI-B using the TAPS detector [2].

  6. Neutron-rich nuclei studied with AMD

    International Nuclear Information System (INIS)

    Antisymmetrized molecular dynamics (AMD) which is a newly constructed theory of quantum-mechanical microscopic simulation of heavy ion collisions is explained to present us with a very useful theoretical approach for the study of the structure-changes which occur when we go from ordinary nuclei to exotic neutron-rich nuclei. It is because of the flexible nature of the AMD wave function which can describe the formation and dissolution of clusters both in collision problems and in structure problems. After brief explanation of successful applications of AMD to heavy ion collisions and that of the frictional cooling technique for constructing minimum-energy wave functions, the results of the AMD analyses of Li, Be, and B isotopes are discussed. Very good reproduction of magnetic moments is obtained and is explained to be related with the structure-change between cluster structure and shell-model-like structure within each isotope. The superposition of AMD determinants is shown to reproduce neutron halo structure. (orig.)

  7. Experiments with stored relativistic exotic nuclei

    International Nuclear Information System (INIS)

    Beams of relativistic exotic nuclei were produced, separated and investigated with the combination of the fragment separator FRS and the storage ring ESR. The following experiments are presented: (1) Direct mass measurements of relativistic nickel and bismuth projectile fragments were performed using Schottky spectrometry. Applying electron cooling, the relative velocity spread of the circulating secondary nuclear beams of low intensity was reduced to below 10-6. The achieved mass resolving power of m/Δm = 6.5 . 105 (FWHM) in recent measurements represents an improvement by a factor of two compared to our previous experiments. The previously unknown masses of more than 100 proton-rich isotopes have been measured in the range of 54 ≤ Z ≤ 84. The results are compared with mass models and estimated values based on extrapolations of experimental values. (2) Exotic nuclei with half-lives shorter than the time required for electron cooling can be investigated by time-of-flight measurements with the ESR being operated in the isochronous mode. This novel experimental technique has been successfully applied in a first measurement with nickel fragments. A mass resolving power of m/Δm = 1.5 . 105 (FWHM) was achieved in this mode of operation. (3) Nuclear half-lives of stored and cooled bare projectile fragments have been measured to study the influence of the ionic charge state on the beta-decay probability. (orig.)

  8. Theoretical Search for RNA Folding Nuclei

    Directory of Open Access Journals (Sweden)

    Leonid B. Pereyaslavets

    2015-11-01

    Full Text Available The functions of RNA molecules are defined by their spatial structure, whose folding is regulated by numerous factors making RNA very similar to proteins. Prediction of RNA folding nuclei gives the possibility to take a fresh look at the problems of the multiple folding pathways of RNA molecules and RNA stability. The algorithm previously developed for prediction of protein folding nuclei has been successfully applied to ~150 various RNA structures: hairpins, tRNAs, structures with pseudoknots, and the large structured P4-P6 domain of the Tetrahymena group I intron RNA. The calculated Φ-values for tRNA structures agree with the experimental data obtained earlier. According to the experiment the nucleotides of the D and T hairpin loops are the last to be involved in the tRNA tertiary structure. Such agreement allowed us to do a prediction for an example of large structured RNA, the P4-P6 RNA domain. One of the advantages of our method is that it allows us to make predictions about the folding nucleus for nontrivial RNA motifs: pseudoknots and tRNA.

  9. A quark structure of hadrons and nuclei

    International Nuclear Information System (INIS)

    In this review we look into the recent understanding of mesons, baryons and nuclei as few quark bound states within the framework of quantum chromodynamics (QCD). In particular, we have reviewed our understanding of the nature of confining interaction, the spin - dependence of colour forces and the role of non-perturbative effects in the study of quark forces in the potential model approach. We also give a comparative study of results obtained by several potential models with reference to the experimental data. We find that although the Lorentz nature of confinement and the nature of spin-dependent colour forces have been better understood now, only a partial understanding of these problems are obtained so far. Our study reveals that properties of baryons could be explained by the same potential model which successfully describe the mesons. However, the nuclei require chiral symmetry and non-perturbative methods for their description. We also discuss the relation between constituent, current and dynamical quark masses. We conclude that QCD motivated approaches have shown much success in explaining many results on hadronic and nuclear data. (author). 212 refs, 14 tabs

  10. Studies of nuclei using radioactive beams

    International Nuclear Information System (INIS)

    The 12 month period from May 1988 to July 1989 represents the first full year of our 18 month pilot program in nuclear structure research. In this period, research was initiated to develop a capability for radioactive secondary beams at Argonne National Laboratory using the Atlas and the new Fragment Mass Analyzer (FMA), which is currently under construction. Two major new detector facilities are currently in the final stages of design and testing. The Large-Area, Scintillator Telescope (LAST) detector is fully operational and will be shipped to Argonne National Laboratory in August for fit-tests and in-beam calibrations. The first segments of a new sixteen-segment neutron multiplicity detector have been built and tested. The remaining segments are currently being constructed. Research was continued in the areas of (1) Coulomb excitation studies of rare earth and actinide nuclei; (2) In-beam, gamma-ray spectroscopy of nuclei in the mass 100 region, and (3) Advanced detector design. Several journal articles and abstracts were published or submitted for publication in the reporting period, and others are currently in preparation. Three graduate students participated in the program, one from the University of Florida and two from the Royal Institute of Technology, Stockholm, Sweden

  11. Approximate particle number projection in hot nuclei

    International Nuclear Information System (INIS)

    Heated finite systems like, e.g., hot atomic nuclei have to be described by the canonical partition function. But this is a quite difficult technical problem and, as a rule, the grand canonical partition function is used in the studies. As a result, some shortcomings of the theoretical description appear because of the thermal fluctuations of the number of particles. Moreover, in nuclei with pairing correlations the quantum number fluctuations are introduced by some approximate methods (e.g., by the standard BCS method). The exact particle number projection is very cumbersome and an approximate number projection method for T ≠ 0 basing on the formalism of thermo field dynamics is proposed. The idea of the Lipkin-Nogami method to perform any operator as a series in the number operator powers is used. The system of equations for the coefficients of this expansion is written and the solution of the system in the next approximation after the BCS one is obtained. The method which is of the 'projection after variation' type is applied to a degenerate single j-shell model. 14 refs., 1 tab

  12. GABAA Receptor Kinetics in the Cerebellar Nuclei: Evidence for Detection of Transmitter from Distant Release Sites

    OpenAIRE

    Pugh, Jason R.; Raman, Indira M.

    2004-01-01

    Neurons of the cerebellar nuclei receive GABAergic input from Purkinje cells. Purkinje boutons have several closely spaced presynaptic densities without GABA transporters, raising the possibility that neurotransmitter released by one presynaptic site diffuses to multiple postsynaptic sites. To test whether such local spillover may contribute to transmission, we studied gating of GABAA receptors at 31–33°C in cerebellar nuclear neurons acutely dissociated from mice. Currents were evoked by rap...

  13. Serotonergic modulation and its influence on signal processing at cellular level in deep cerebellar nuclei neurons

    OpenAIRE

    Lee, Meng-Larn

    2007-01-01

    Deep cerebellar nuclei (DCN) neurons generate the final output of cerebellum and receive abundant modulatory serotonergic inputs from brainstem neurons. The aim of this present study was to elucidate the influence of serotonin on signal processing performed by DCN neurons. Since signal processing is determined by the interplay between intrinsic and synaptic properties, the impact of serotonin on intrinsic as well as synaptic properties was investigated. To this end whole-cell patch clamp reco...

  14. Beta-decay spectroscopy of r-process nuclei around N = 126

    Directory of Open Access Journals (Sweden)

    Hirayama Y.

    2016-01-01

    Full Text Available KEK Isotope Separation System (KISS has been developed at RIKEN to study the β-decay properties of neutron-rich isotopes with neutron numbers around N = 126 to understand the astrophysical site of r-process. These nuclei will be produced by multi-nucleon transfer reactions in neutron-rich heavy ion collisions between 136Xe beam and 198Pt target. The KISS consists of an argon gas cell combined with a laser resonance ionization technique for atomic number selection, of an ISOL mass-separation system and of a detector system for the β-decay spectroscopy of nuclei around N = 126. The argon gas cell of KISS is a key component for thermalizing (stopping and neutralizing and accumulating the unstable nuclei, and selectively ionizing them by using laser. We have performed off-and on-line experiments to study the basic properties of the gas cell as well as KISS. We successfully extracted the laser-ionized stable 198Pt atoms from the KISS at the commissioning on-line experiments. We furthermore extracted laser-ionized unstable 199Pt atoms and confirmed that the measured half-life was in good agreement with the reported value. Now KISS is ready for lifetime measurements of Pt, Ir, and Os isotopes around N = 126.

  15. Mitochondria and nuclei dual-targeted heterogeneous hydroxyapatite nanoparticles for enhancing therapeutic efficacy of doxorubicin.

    Science.gov (United States)

    Xiong, Hui; Du, Shi; Ni, Jiang; Zhou, Jianping; Yao, Jing

    2016-07-01

    Dual-targeted nanoparticles have been increasingly used to realize greater anti-proliferation effect by attacking double key sites of tumor cells. In order to retain nuclei inhibition effect and enhance DOX-induced apoptosis by mitochondrial pathway simultaneously, hyaluronic acid (HA) modified hydroxyapatite (HAP) nanoparticles (HAP-HA), the functional calcium-based tumor targeting nanoparticles, have been developed. In this nanosystem, HA acts as an active tumor-targeting ligand to bind the CD44 receptors which are overexpressed on the surface of tumor cells while HAP can load and deliver DOX to both nuclei and mitochondria of tumor cells. In this study, DOX-loaded HAP-HA nanoparticles (DOX/HAP-HA) exhibited satisfactory drug loading efficiency which was up to 214.55 ± 51.05 μg mg(-1) and showed a uniform nano-scaled particle size. The mitochondrial and nuclei targetability of DOX/HAP-HA was confirmed by confocal laser scanning microscopy analyses. Besides, western blot assay demonstrated that DOX/HAP-HA could markedly enhance mitochondrial cytochrome C leakage and thereby activate apoptotic cascade associated with it. In addition, in vivo anti-tumor efficacy and toxicity evaluation of DOX/HAP-HA indicated that DOX/HAP-HA was more effective and less harmful compared to other groups. DOX/HAP-HA might be a new promising targeted delivery system for effective cancer therapy. PMID:27105438

  16. Filtering, reconstruction, and measurement of the geometry of nuclei from hippocampal neurons based on confocal microscopy data.

    Science.gov (United States)

    Queisser, Gillian; Wittmann, Malte; Bading, Hilmar; Wittum, Gabriel

    2008-01-01

    The cell nucleus is often considered a spherical structure. However, the visualization of proteins associated with the nuclear envelope in rat hippocampal neurons indicates that the geometry of nuclei is far more complex. The shape of cell nuclei is likely to influence the nucleo-cytoplasmic exchange of macromolecules and ions, in particular calcium, a key regulator of neuronal gene expression. We developed a tool to retrieve the 3-D view of cell nuclei from laser scanning confocal microscopy data. By applying an inertia-based filter, based on a special structure detection mechanism, the signal-to-noise ratio of the image is enhanced, the signal is smoothed, gaps in the membrane are closed, while at the same time the geometric properties, such as diameters of the membrane, are preserved. After segmentation of the image data, the microscopy data are sufficiently processed to extract surface information of the membrane by creating an isosurface with a marching tetrahedra algorithm combined with a modified Dijkstra graph-search algorithm. All methods are tested on artificial data, as well as on real data, which are recorded with a laser scanning confocal microscope. Significant advantages of the inertia-based filter can be observed when comparing it to other state of the art nonlinear diffusion filters. An additional program is written to calculate surface and volume of cell nuclei. These results represent the first step toward establishing a geometry-based model of the-dynamics of cytoplasmic and nuclear calcium. PMID:18315367

  17. Study of the isomer nuclei produced in the spontaneous fission of 252Cf

    International Nuclear Information System (INIS)

    Isomeric states have been studied in fission fragments produced by spontaneous fission of 252Cf. 34 isomeric nuclei have been identified by using coincidences between γ-rays detected in EUROGAM II and fission fragments detected in photovoltaic cells. Lifetimes from 20 ns up to 2 μs have been measured. Microscopic interpretation of the isomeric levels discovered has been tried by means of the Hartree-Fock-Bogolyubov procedure using Gogny force. It was found that the 152,154,156Nd nuclei have prolate deformation in their ground state; the rotational band built on this ground state is well reproduced by the calculation. For these nuclei the 2 quasi-particle excited states energies are above 1 MeV in agreement with the experiment. The computation confirms the similitude of the 156Nd and 158Sm isomeric states associated to neutron 2 quasi-particles of Jπ Kπ = 5- (ν 5/2 (642) x ν 5/2 (523)) while such similitude does not occur for the isotone nuclei 154Nd and 156Sm. The computation predicts a proton 2 quasi-particle excited states of Jπ = 5-, near the isomeric level measured in 156Sm but not for that of 154Nd. Concerning the 152Nd the calculated level density is very near that of the states measured in the 1.6 to 2.3 MeV interval. However, the lack of precise information on spins and parities of the measured levels does make not possible a confrontation with the calculations. An up-graded equipment implying 32 photovoltaic cells instead of 2 cells is to be developed and installed by the EUROGAM

  18. Compressed Baryonic Matter: from Nuclei to Pulsars

    CERN Document Server

    Xu, Renxin

    2013-01-01

    Our world is wonderful because of the negligible baryonic part although unknown dark matter and dark energy dominate the Universe. Those nuclei in the daily life are forbidden to fuse by compression due to the Coulomb repulse, nevertheless, it is usually unexpected in extraterrestrial extreme-environments: the gravity in a core of massive evolved star is so strong that all the other forces (including the Coulomb one) could be neglected. Compressed baryonic matter is then produced after supernova, manifesting itself as pulsar-like stars observed. The study of this compressed baryonic matter can not only be meaningful in fundamental physics (e.g., the elementary color interaction at low-energy scale, testing gravity theories, detecting nano-Hertz background gravitational waves), but has also profound implications in engineering applications (including time standard and navigation), and additionally, is focused by Chinese advanced telescopes, either terrestrial or in space. Historically, in 1930s, L. Landau spec...

  19. Nuclei as superposition of topological solitons

    International Nuclear Information System (INIS)

    The rational map approximation provides an opportunity to describe light nuclei as classical solitons with baryon number B > 1 in the framework of the Skyrme model. The rational map ansatz yields a possibility of factorization of S3 baryon charge into S1 and S2 parts, the phenomenology of the model being strongly affected by the chosen factorization. Moreover, in the fundamental representation superposition of two different soliton factorizations can be used as solution ansatz. The canonical quantization procedure applied to collective degrees of freedom of the classical soliton leads to anomalous breaking of the chiral symmetry and exponential falloff of the energy density of the soliton at large distance, without explicit symmetry breaking terms included. The evolution of the shape of electric form factor as a function of two different factorization soliton mix ratio is investigated. Numerical results are presented. (author)

  20. Diffraction on nuclei: Effects of nucleon correlations

    International Nuclear Information System (INIS)

    The cross sections for a variety of diffractive processes in proton-nucleus scattering, associated with large gaps in rapidity, are calculated within an improved Glauber-Gribov theory, where the inelastic shadowing corrections are summed to all orders by employing the dipole representation. The effects of nucleon correlations, leading to a modification of the nuclear thickness function, are also taken into account. Numerical calculations are performed for the energies of the Hadron-Electron Ring Accelerator-B experiment, the Relativistic Heavy Ion Collider and Large Hadron Collider, and for several nuclei. It is found that whereas the Gribov corrections generally make nuclear matter more transparent, nucleon correlations act in the opposite direction and have important effects in various diffractive processes.