Evaluation of Membrane Ultrafiltration and Residual Chlorination as a Decentralized Water Treatment Strategy for Ten Rural Healthcare Facilities in Rwanda

Directory of Open Access Journals (Sweden)

Alexandra Huttinger

2015-10-01

Full Text Available There is a critical need for safe water in healthcare facilities (HCF in low-income countries. HCF rely on water supplies that may require additional on-site treatment, and need sustainable technologies that can deliver sufficient quantities of water. Water treatment systems (WTS that utilize ultrafiltration membranes for water treatment can be a useful technology in low-income countries, but studies have not systematically examined the feasibility of this technology in low-income settings. We monitored 22 months of operation of 10 WTS, including pre-filtration, membrane ultrafiltration, and chlorine residual disinfection that were donated to and operated by rural HCF in Rwanda. The systems were fully operational for 74% of the observation period. The most frequent reasons for interruption were water shortage (8% and failure of the chlorination mechanism (7%. When systems were operational, 98% of water samples collected from the HCF taps met World Health Organization (WHO guidelines for microbiological water quality. Water quality deteriorated during treatment interruptions and when water was stored in containers. Sustained performance of the systems depended primarily on organizational factors: the ability of the HCF technician to perform routine servicing and repairs, and environmental factors: water and power availability and procurement of materials, including chlorine and replacement parts in Rwanda.

Fatigue behavior of austenitic steels. Subproject. Mechanism oriented investigation of the fatigue behavior of austenitic steel X6CrNiNb1810 in the HCF and VHCF regime. Final report; Ermuedungsverhalten Austenit. Teilprojekt. Mechanismenorientierte Untersuchung des Ermuedungsverhaltens des austenitischen Stahles X6CrNiNb1810 im HCF- und VHCF-Bereich. Abschlussbericht

Energy Technology Data Exchange (ETDEWEB)

Sorich, A.; Smaga, M.; Eifler, D.

2015-01-23

In addition to load cycles in the Low Cycle Fatigue (LCF)-regime due to start up and shut down procedures of power plants, in some components additional high-frequency loadings in the High Cycle Fatigue (HCF)- and Very High Cycle Fatigue (VHCF)-regime occur. These loadings are induced e.g. by stresses due to thermal cyclic fluctuations and fluid dynamic processes. Therefore it is necessary to characterize experimentally the cyclic deformation behavior of metastable austenitic steels at operating temperature particularly in the HCF- and VHCF-regime and to develop a nondestructive method to detect fatigue processes. This joint research project was conducted in cooperation between the Institute of Materials Science and Engineering (WKK) of the University of Kaiserslautern and the Fraunhofer-Institute for Non-Destructive Testing (IZFP) in Saarbruecken. WKK was focused on experimental investigations to characterize the cyclic deformation behavior of the metastable austenitic steel in the HCF- and VHCF-range, taking into account cyclic hardening and softening processes and in particular to consider fatigue-induced changes in microstructure. The IZFP has focused on the development and application of a testing concept based on electromagnetic ultrasonic measurements. The isothermal cyclic deformation behavior of the metastable austenitic steel X6CrNiNb1810 (1.4550, AISI 347) at 300 C in the HCF-range is characterized by cyclic softening until specimen failure. At strain amplitudes of 0.10 % ≤ ε{sub a,t} ≤ 0.15 % and the stress amplitude σ{sub a} = 160 MPa cyclic softening is followed by cyclic hardening, which results in a significant increase in life time, up to the limiting number of cycles, which was defined at N{sub I} = 10{sup 7} in HCF-regime. The cyclic hardening is determined by a transformation induced phase formation from face-centered cubic (fcc) austenite to body-centered cubic (bcc) α{sup '}-martensite and/or in hexagonal (hcp) ε-martensite. In

Non-destructive detection of fatigue in austenitic steel X6CrNiNb1810 in the HCF and VHCF range. Final report; Zerstoerungsfreie Detektion der Ermuedung von austenitischem Stahl X6CrNiNb1810 im HCF- und VHCF-Bereich. Abschlussbericht

Energy Technology Data Exchange (ETDEWEB)

Seiler, Georg; Boller, Christian [Univ. des Saarlandes, Saarbruecken (Germany). Lehrstuhl fuer Zerstoerungsfreie Pruefung und Qualitaetsmanagement

2014-12-31

In addition to load cycles in the Low Cycle Fatigue (LCF)-regime due to start up and shut down procedures of power plants, in some components additional high-frequency loadings in the High Cycle Fatigue (HCF)- and Very High Cycle Fatigue (VHCF)-regime occur. These loadings are induced e.g. by stresses due to thermal cyclic fluctuations and fluid dynamic processes. Therefore it is necessary to characterize experimentally the cyclic deformation behavior of metastable austenitic steels at operating temperature particularly in the HCF- and VHCF-regime and to develop a nondestructive method to detect fatigue processes. This joint research project was conducted in cooperation between the Institute of Materials Science and Engineering (WKK) of the University of Kaiserslautern and the Chair of Non-Destructive Testing and Quality Assurance of Saarland University (LZfPQ). WKK was focused on experimental investigations of the cyclic deformation behavior of metastable austenitic steel in the HCF- and VHCF-range, taking into account cyclic hardening and softening processes and in particular to consider fatigue-induced changes in microstructure. The samples were taken from a real pressurized water reactor component (surgeline). LZfPQ has focused on the development and application of a testing concept based on electromagnetic ultrasonic measurements. Within this subproject, electromagnetic acoustic transducers (EMATs) for in situ Operation in WKK's fatigue testing equipment have been developed and assembled. Single-step fatigue tests at elevated temperature (300 C) were conducted both with total-stress and strain control. During the test, the fatigue specimens were characterized by EMAT ultrasound in transmission mode. Different sensor types and wavemodes were used. The transmission signal was evaluated in terms of time of flight and amplitude. Both measured values are seen to behave in a characteristic manner depending on the test duration and the mechanical measured value

Interference Cancellation for Hollow-Core Fiber Reference Cells

DEFF Research Database (Denmark)

Seppä, Jeremias; Merimaa, Mikko; Merimaa, Mikko

2015-01-01

Doppler-free saturated absorption spectroscopy of gases in hollow-core fiber (HCF)-based cells can be used for realizing new compact, robust, and portable frequency standards. In this paper, methods for cancelling interferences resulting from the optical connections between standard fiber and HCF...... and other factors such as varying coupling to HCF modes are investigated. Laser power modulation with simultaneous detection of ac and dc signal is used to separate saturated absorption from interferences. In addition, a technique of two piezoelectric stack actuators stretching the fiber at different...... locations is described. The presented experimental results demonstrate that 99% interference attenuation is readily attainable with the techniques. Frequency comb-referenced measurement of saturated acetylene absorption features near 1.54 μm, with fiber length and power modulation, is presented...

Hot-cell verification facility

International Nuclear Information System (INIS)

Eschenbaum, R.A.

1981-01-01

The Hot Cell Verification Facility (HCVF) was established as the test facility for the Fuels and Materials Examination Facility (FMEF) examination equipment. HCVF provides a prototypic hot cell environment to check the equipment for functional and remote operation. It also provides actual hands-on training for future FMEF Operators. In its two years of operation, HCVF has already provided data to make significant changes in items prior to final fabrication. It will also shorten the startup time in FMEF since the examination equipment will have been debugged and operated in HCVF

Hot cell verification facility update

International Nuclear Information System (INIS)

Titzler, P.A.; Moffett, S.D.; Lerch, R.E.

1985-01-01

The Hot Cell Verification Facility (HCVF) provides a prototypic hot cell mockup to check equipment for functional and remote operation, and provides actual hands-on training for operators. The facility arrangement is flexible and assists in solving potential problems in a nonradioactive environment. HCVF has been in operation for six years, and the facility is a part of the Hanford Engineering Development Laboratory

The Role of Titanium Surface Microtopography on Adhesion, Proliferation, Transformation, and Matrix Deposition of Corneal Cells.

Science.gov (United States)

Zhou, Chengxin; Lei, Fengyang; Chodosh, James; Paschalis, Eleftherios I

2016-04-01

Titanium (Ti) is an excellent implantable biomaterial that can be further enhanced by surface topography optimization. Despite numerous data from orthopedics and dentistry, the effect of Ti surface topography on ocular cells is still poorly understood. In light of the recent adaptation of Ti in the Boston Keratoprosthesis artificial cornea, we attempted to perform an extended evaluation of the effect of Ti surface topography on corneal cell adhesion, proliferation, cytotoxicity, transformation, and matrix deposition. Different surface topographies were generated on medical grade Ti-6Al-4V-ELI (extra-low interstitial), with linearly increased roughness (polished to grit blasted). Biological response was evaluated in vitro using human corneal limbal epithelial (HCLE) cells, stromal fibroblasts (HCF), and endothelial cells (HCEnC). None of the Ti surface topographies caused cytotoxicity to any of the three corneal cell types. However, rough Ti surface inhibited HCLE and HCF cell adhesion and proliferation, while HCEnC proliferation was unaffected. Long-term experiments with HCF revealed that rough Ti surface with R(a) (the arithmetic average of the profile height from the mean line) ≥ 1.15 μm suppressed HCF focal adhesion kinase phosphorylation, changed fibroblast morphology, and caused less aligned and reduced deposition of collagen matrix as compared to smooth Ti (R(a) ≤ 0.08 μm). In the presence of transforming growth factor β1 (TGFβ1) stimulation, rough Ti inhibited alpha-smooth muscle actin (α-SMA) expression and collagen deposition, leading to decreased myofibroblast transformation and disorganization of the collagen fibrils as compared to smooth Ti. This study suggests that Ti surface topography regulates corneal cell behavior in a tissue-dependent manner that varies across the corneal strata. Contrary to the accepted paradigm, smooth surface topography can enhance cell adhesion and proliferation and increase matrix deposition by corneal cells.

Patient-driven resource planning of a health care facility evacuation.

Science.gov (United States)

Petinaux, Bruno; Yadav, Kabir

2013-04-01

The evacuation of a health care facility is a complex undertaking, especially if done in an immediate fashion, ie, within minutes. Patient factors, such as continuous medical care needs, mobility, and comprehension, will affect the efficiency of the evacuation and translate into evacuation resource needs. Prior evacuation resource estimates are 30 years old. Utilizing a cross-sectional survey of charge nurses of the clinical units in an urban, academic, adult trauma health care facility (HCF), the evacuation needs of hospitalized patients were assessed periodically over a two-year period. Survey data were collected on 2,050 patients. Units with patients having low continuous medical care needs during an emergency evacuation were the postpartum, psychiatry, rehabilitation medicine, surgical, and preoperative anesthesia care units, the Emergency Department, and Labor and Delivery Department (with the exception of patients in Stage II labor). Units with patients having high continuous medical care needs during an evacuation included the neonatal and adult intensive care units, special procedures unit, and operating and post-anesthesia care units. With the exception of the neonate group, 908 (47%) of the patients would be able to walk out of the facility, 492 (25.5%) would require a wheelchair, and 530 (27.5%) would require a stretcher to exit the HCF. A total of 1,639 patients (84.9%) were deemed able to comprehend the need to evacuate and to follow directions; the remainder were sedated, blind, or deaf. The charge nurses also determined that 17 (6.9%) of the 248 adult intensive care unit patients were too ill to survive an evacuation, and that in 10 (16.4%) of the 61 ongoing surgery cases, stopping the case was not considered to be safe. Heath care facilities can utilize the results of this study to model their anticipated resource requirements for an emergency evacuation. This will permit the Incident Management Team to mobilize the necessary resources both within

Interaction of MYC with host cell factor-1 is mediated by the evolutionarily conserved Myc box IV motif.

Science.gov (United States)

Thomas, L R; Foshage, A M; Weissmiller, A M; Popay, T M; Grieb, B C; Qualls, S J; Ng, V; Carboneau, B; Lorey, S; Eischen, C M; Tansey, W P

2016-07-07

The MYC family of oncogenes encodes a set of three related transcription factors that are overexpressed in many human tumors and contribute to the cancer-related deaths of more than 70,000 Americans every year. MYC proteins drive tumorigenesis by interacting with co-factors that enable them to regulate the expression of thousands of genes linked to cell growth, proliferation, metabolism and genome stability. One effective way to identify critical co-factors required for MYC function has been to focus on sequence motifs within MYC that are conserved throughout evolution, on the assumption that their conservation is driven by protein-protein interactions that are vital for MYC activity. In addition to their DNA-binding domains, MYC proteins carry five regions of high sequence conservation known as Myc boxes (Mb). To date, four of the Mb motifs (MbI, MbII, MbIIIa and MbIIIb) have had a molecular function assigned to them, but the precise role of the remaining Mb, MbIV, and the reason for its preservation in vertebrate Myc proteins, is unknown. Here, we show that MbIV is required for the association of MYC with the abundant transcriptional coregulator host cell factor-1 (HCF-1). We show that the invariant core of MbIV resembles the tetrapeptide HCF-binding motif (HBM) found in many HCF-interaction partners, and demonstrate that MYC interacts with HCF-1 in a manner indistinguishable from the prototypical HBM-containing protein VP16. Finally, we show that rationalized point mutations in MYC that disrupt interaction with HCF-1 attenuate the ability of MYC to drive tumorigenesis in mice. Together, these data expose a molecular function for MbIV and indicate that HCF-1 is an important co-factor for MYC.

Royal Jelly-Mediated Prolongevity and Stress Resistance in Caenorhabditis elegans Is Possibly Modulated by the Interplays of DAF-16, SIR-2.1, HCF-1, and 14-3-3 Proteins.

Science.gov (United States)

Wang, Xiaoxia; Cook, Lauren F; Grasso, Lindsay M; Cao, Min; Dong, Yuqing

2015-07-01

Recent studies suggest that royal jelly (RJ) and its related substances may have antiaging properties. However, the molecular mechanisms underlying the beneficial effects remain elusive. We report that the effects of RJ and enzyme-treated RJ (eRJ) on life span and health span in Caenorhabditis elegans (C elegans) are modulated by the sophisticated interplays of DAF-16, SIR-2.1, HCF-1, and 14-3-3 proteins. Dietary supplementation with RJ or eRJ increased C. elegans life span in a dose-dependent manner. The RJ and eRJ consumption increased the tolerance of C elegans to oxidative stress, ultraviolet irradiation, and heat shock stress. Our genetic analyses showed that RJ/eRJ-mediated life-span extension requires insulin/IGF-1 signaling and the activities of DAF-16, SIR-2.1, HCF-1, and FTT-2, a 14-3-3 protein. Earlier studies reported that DAF-16/FOXO, SIR-2.1/SIRT1, FTT-2, and HCF-1 have extensive interplays in worms and mammals. Our present findings suggest that RJ/eRJ-mediated promotion of longevity and stress resistance in C elegans is dependent on these conserved interplays. From an evolutionary point of view, this study not only provides new insights into the molecular mechanisms of RJ's action on health span promotion in C elegans, but also has imperative implications in using RJ/eRJ as nutraceuticals to delay aging and age-related disorders. © The Author 2014. Published by Oxford University Press on behalf of The Gerontological Society of America. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

Characterisation study of radionuclides in Hot Cell Facility

International Nuclear Information System (INIS)

Ghare, P.T.; Rath, D.P.; Govalkar, Atul; Mukherjee, Govinda; AniIKumar, S.; Yadav, R.K.B.; Mallik, G.K.

2016-01-01

Examination of different types of experimental as well as power reactor irradiated fuels and validation of fuel modeling codes is carried out in general Hot cell facility. The Hot cell facility has six concrete shielded hot cells, capable of handling radioactivity varying from 3.7 TBQ to 3700 TBq gamma activity. The facility was augmented with two hot cells having designed capacity to handle radioactivity of 9250 TBQ of equivalent activity of 60 Co. The study of characterization of various radionuclides present inside the hot cell of PIE facility was taken up. This study will help in providing valuable inputs for various radiological safety parameters to keep personnel exposure to ALARA level as per the mandate of radiation safety program

A role for topographic cues in the organization of collagenous matrix by corneal fibroblasts and stem cells.

Directory of Open Access Journals (Sweden)

Dimitrios Karamichos

Full Text Available Human corneal fibroblasts (HCF and corneal stromal stem cells (CSSC each secrete and organize a thick stroma-like extracellular matrix in response to different substrata, but neither cell type organizes matrix on tissue-culture polystyrene. This study compared cell differentiation and extracellular matrix secreted by these two cell types when they were cultured on identical substrata, polycarbonate Transwell filters. After 4 weeks in culture, both cell types upregulated expression of genes marking differentiated keratocytes (KERA, CHST6, AQP1, B3GNT7. Absolute expression levels of these genes and secretion of keratan sulfate proteoglycans were significantly greater in CSSC than HCF. Both cultures produced extensive extracellular matrix of aligned collagen fibrils types I and V, exhibiting cornea-like lamellar structure. Unlike HCF, CSSC produced little matrix in the presence of serum. Construct thickness and collagen organization was enhanced by TGF-ß3. Scanning electron microscopic examination of the polycarbonate membrane revealed shallow parallel grooves with spacing of 200-300 nm, similar to the topography of aligned nanofiber substratum which we previously showed to induce matrix organization by CSSC. These results demonstrate that both corneal fibroblasts and stromal stem cells respond to a specific pattern of topographical cues by secreting highly organized extracellular matrix typical of corneal stroma. The data also suggest that the potential for matrix secretion and organization may not be directly related to the expression of molecular markers used to identify differentiated keratocytes.

Decommissioning of the Risoe hot cell facility

International Nuclear Information System (INIS)

Carlsen, H.

1992-02-01

Concise descriptions of actions taken in relation to the decommissioning of the hot cell facility at Risoe National Laboratory are presented. The removal of fissile material, of large contaminated equipment from the concrete cell line and a separate shielded storage facility, and the removal of large contaminated facilities such as out cell parts of a tube transport system between a concrete cell and a lead shielded steel box and a remotely operated Reichert Telatom microscope housed in a lead shielded glove box is described in addition to the initial mapping of radiation levels related to the decontamination of concrete cells. The dose commitment of 17.7 mSv was ascribed to 12 persons in the 2nd half of 1991. The work resulting in these doses was mainly handling of waste together with the frogman entrances in order to repair the in-cell crane and power manipulator. The overall time schedule for the project still appears to be applicable. (AB)

Decommissioning of the Risoe Hot Cell facility

International Nuclear Information System (INIS)

Carlsen, H.

1993-02-01

A concise description of the current status (December 31st, 1992) regarding the decommissioning of the hot cell facility at Risoe National Laboratory is given in this periodic report. During the second half of the year 1992, all remaining fissile material and a large amount of contaminated material were removed, major repair work was carried out on the in-cell crane, the shielded storage facility was decontaminated and sealed, iodine filters in the cell ventilation system were removed, remote cleaning was carried out on three concrete cells to radiation levels acceptable for final cleaning by frogmen, and the remaining work schedule was planned. These processes are briefly described. Some breakdowns of older, but vital equipment (i.e. the in-cell crane and the power manipulator) that was taken into extensive use led to a certain amount of delay. The collective radiation doses during this half-year were no higher than under normal operation of the facility, and amounted to 12 man-mSv ascribed to 14 persons. It was concluded that, when removing old epoxy paint in the cells using paint strippers applied by hand, personnel can wear polythene oversuits, although a technique for remote handling has been developed. Tables illustrate measured radiation levels in cells number 1,4,5 and 6, and a diagram describes the shielded storage facility. (AB)

Decommissioning of the Risoe Hot Cell facility

International Nuclear Information System (INIS)

Carlsen, H.

1994-06-01

Nuclear fuels have been handled and examined after irradiation by physical and chemical techniques, and radiotherapy sources, mainly 60 Co, have been produced at Risoe National Laboratory since 1964. The aims of decommissioning (during 1990-94, at IAEA Stage 2 level for reactors) were to obtain safe conditions for the remaining parts of the facility and to produce clean space areas for new projects. The facility comprises 6 concrete cells, several lead-shielded steel cells, glove boxes, shielded storage for waste, a remotely operated optical microscope, a frogman area for personnel access to the concrete cells, a decontamination facility, workshops and safety installations. All steel cells, glove boxes and the microscope were emptied and removed. The concrete cells were emptied of fissile material, scientific equipment, general tools and scrap. Decontamination should facilitate waste packing and reduce amount of waste to be stored temporarily at the Risoe waste treatment facility together with highly active waste. The concrete cells were cleaned remotely by wiping, hot spot removal, by mechanical means and vacuum cleaning. The interiors of 2 cells were decontaminated by high pressure water jetting. All master-slave manipulators and part of the contaminated ventilation system at the cells were removed. The cells are left in a non-ventilated state, connected to the atmosphere by an absolute filter. The main contaminants measured before cell closure were 60 Co, 137 Cs and alpha-emitters. Dismantling, decontamination waste disposal and received doses are described. Simple techniques involving low doses were found to be very effective. (AB)

Surface modification of amine-functionalised graphite for preparation of cobalt hexacyanoferrate (CoHCF)-modified electrode: an amperometric sensor for determination of butylated hydroxyanisole (BHA).

Science.gov (United States)

Prabakar, S J Richard; Narayanan, S Sriman

2006-12-01

A cobalt hexacyanoferrate (CoHCF)-modified graphite paraffin wax composite electrode was prepared by a new approach. An amine-functionalised graphite powder was used for the fabrication of the electrode. A functionalised graphite paraffin wax composite electrode was prepared and the surface of the electrode was modified with a thin film of CoHCF. Various parameters that influence the electrochemical behaviour of the modified electrode were studied by varying the background electrolytes, scan rates and pH. The modified electrode showed good electrocatalytic activity towards the oxidation of butylated hydroxyanisole (BHA) under optimal conditions and showed a linear response over the range from 7.9 x 10(-7) to 1.9 x 10(-4) M of BHA with a correlation coefficient of 0.9988. The limit of detection was 1.9 x 10(-7) M. Electrocatalytic oxidation of BHA was effective at the modified electrode at a significantly reduced potential and at a broader pH range. The utility of the modified electrode as an amperometric sensor for the determination of BHA in flow systems was evaluated by carrying out hydrodynamic and chronoamperometric experiments. The modified electrode showed very good stability and a longer shelf life. The modified electrode was applied for the determination of BHA in spiked samples of chewing gum and edible sunflower oil. The advantage of this method is the ease of electrode fabrication, good stability, longer shelf life, low cost and its diverse application for BHA determination.

Current status of JAERI Tokai hot cell facilities

International Nuclear Information System (INIS)

Itami, Hiroharu; Morozumi, Minoru; Yamahara, Takeshi

1992-01-01

JAERI has 4 hot cell facilities in order to examine high radioactive materials. Three of them, the Research Hot Laboratory, the Reactor Fuel Examination Facility and the Waste Safety Testing Facility are located in the JAERI Tokai site, and the rest is the JMTR Hot Laboratory in the Oarai site. The Research Hot Laboratory (RHL) was constructed for post-irradiation examination (PIE), especially nuclear related basic research experiment, such as metallurgical, chemical and mechanical examination on fuels and materials irradiated in research and test reactors. This facility has 10 large dimension concrete and 38 lead cells. At present the RHL is used for various kinds of examinations of high radioactive samples such as fuels of research and test reactors, power reactors and high temperature testing reactor (HTTR), and structural materials. The Reactor Fuel Examination Facility (RFEF) was designed and constructed for carrying out PIE of irradiated full-size fuel assemblies of light water reactors (LWRs). This facility has a storage pool, 8 concrete and 5 lead cells. They are currently used for safety evaluation on high burnup and advanced lWR fuels as part of the national program. The Waste Safety Testing Facility (WASTEF) was designed and constructed for safety research on long-term storage and disposal of high level radioactive wastes, generated by fuel reprocessing. The WASTEF has 5 concrete cells and 1 lead cell. Examinations on the behavior of various long-lived fission products in a glass form and in a canister and, releasing behavior of them out of a canister are carrying out under the condition at storage. (author)

Refurbishment of an Analytical Laboratory Hot Cell Facility

International Nuclear Information System (INIS)

Rosenberg, K.; Henslee, S.P.; Michelbacher, J.A.; Coleman, R.M.

1997-01-01

An Analytical Laboratory Hot Cell (ALHC) Facility at Argonne National Laboratory-West (ANL-W) was in service for nearly thirty years. In order to comply with DOE regulations governing such facilities and meet ANL-W programmatic requirements, a major refurbishment effort was undertaken. All penetrations within the facility were sealed; the ventilation system was redesigned, upgraded and replaced; the manipulators were replaced; the hot cell windows were removed, refurbished, and reinstalled; all hot cell utilities were replaced; a lead-shielded glovebox housing an Inductively Coupled Plasma - Atomic Emission Spectrometer (ICP-AES) System was interfaced with the hot cells, and a new CO2 fire suppression system and other ALHC support equipment were installed

Alpha-Gamma Hot-Cell Facility at Argonne National Laboratory East

International Nuclear Information System (INIS)

Neimark, L.A.; Jackson, W.D.; Donahue, D.A.

1979-01-01

The Alpha-Gamma Hot-Cell Facility has been in operation at Argonne National Laboratory East (ANL-E) for 15 years. The facility was designed for plutonium research in support of ANL's LMFBR program. The facility consists of a kilocurie, nitrogen-atmosphere alpha-gamma hot cell and supporting laboratories. Modifications to the facility and its equipment have been made over the years as the workload and nature of the work changed. These modifications included inerting the entire hot cell, adding four work stations, modifying in-loading procedures and examination equipment to handle longer test articles, and changing to a new sodium-vapor lighting system. Future upgrading includes the addition of a decontamination and repair facility, use of radio-controlled transfer carts, refurbishment of the zinc bromide windows, and the installation of an Auger microprobe

Conceptual layout design of CFETR Hot Cell Facility

Energy Technology Data Exchange (ETDEWEB)

Gong, Zheng, E-mail: gongz@mail.ustc.edu.cn [University of Science and Technology of China, Hefei 230026 (China); Institute of Plasma Physics, Chinese Academy of Sciences, Hefei (China); Qi, Minzhong, E-mail: qiminzhong@ipp.ac.cn [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei (China); Cheng, Yong, E-mail: chengyong@ipp.ac.cn [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei (China); Song, Yuntao, E-mail: songyt@ipp.ac.cn [University of Science and Technology of China, Hefei 230026 (China); Institute of Plasma Physics, Chinese Academy of Sciences, Hefei (China)

2015-11-15

Highlights: • This article proposed a conceptual layout design for CFETR. • The design principles are to support efficient maintenance to ensure the realization of high duty time. • The preliminary maintenance process and logistics are described in detail. • Life cycle management, maneuverability, risk and safety are in the consideration of design. - Abstract: CFETR (China Fusion Engineering Test Reactor) is new generation of Tokomak device beyond EAST in China. An overview of hot cell layout design for CFETR has been proposed by ASIPP&USTC. Hot Cell, as major auxiliary facility, not only plays a pivotal role in supporting maintenance to meet the requirements of high duty time 0.3–0.5 but also supports installation and decommissioning. Almost all of the Tokomak devices are lateral handling internal components like ITER and JET, but CFETR maintain the blanket module from 4 vertical ports, which is quite a big challenge for the hot cell layout design. The activated in-vessel components and several diagnosis instruments will be repaired and refurbished in the Hot Cell Facility, so the appropriate layout is very important to the Hot Cell Facility to ensure the high duty time, it is divided into different parts equipped with a variety of RH equipment and diagnosis devices based on the functional requirements. The layout of the Hot Cell Facility should make maintenance process more efficient and reliable, and easy to service and rescue when a sudden events taking place, that is the capital importance issue considered in design.

New facilities of the ECN hot cell laboratory

International Nuclear Information System (INIS)

Duijves, K.A.; Konings, R.J.M.

1996-04-01

A description is given of two recent expansions of the ECN Hot Cell Laboratory in Petten; a production facility for molybdenum-99 and an actinide laboratory, a special facility to investigate unirradiated alpha- and beta-active samples. (orig.)

Decontamination of an Analytical Laboratory Hot Cell Facility

International Nuclear Information System (INIS)

Michelbacher, J.A.; Henslee, S.P.; Rosenberg, K.E.; Coleman, R.M.

1995-11-01

An Analytical Laboratory Hot Cell Facility at Argonne National Laboratory-West (ANL-W) had been in service for nearly thirty years. In order to comply with current DOE regulations governing such facilities and meet programmatic requirements, a major refurbishment effort was mandated. Due to the high levels of radiation and contamination within the cells, a decontamination effort was necessary to provide an environment that permitted workers to enter the cells to perform refurbishment activities without receiving high doses of radiation and to minimize the potential for the spread of contamination. State-of-the-art decontamination methods, as well as time-proven methods were utilized to minimize personnel exposure as well as maximize results

Small Water Enterprise in Rural Rwanda: Business Development and Year-One Performance Evaluation of Nine Water Kiosks at Health Care Facilities.

Science.gov (United States)

Huttinger, Alexandra; Brunson, Laura; Moe, Christine L; Roha, Kristin; Ngirimpuhwe, Providence; Mfura, Leodomir; Kayigamba, Felix; Ciza, Philbert; Dreibelbis, Robert

2017-12-16

Small water enterprises (SWEs) have lower capital expenditures than centralized systems, offering decentralized solutions for rural markets. This study evaluated SWEs in rural Rwanda, where nine health care facilities (HCF) owned and operated water kiosks supplying water from onsite water treatment systems (WTS). SWEs were monitored for 12 months. Spearman's Rank Correlation Coefficient (r s ) was used to evaluate correlations between demand for kiosk water and community characteristics, and between kiosk profit and factors influencing the cost model. On average, SWEs distributed 15,300 L/month. One SWE ran at a loss, four had profit margins of ≤10% and four had profit margins of 45-75%. Factors influencing SWE performance were intermittent water supply (87% of SWE closures were due to water shortage), consumer demand (demand was high where populations already used improved water sources (r s = 0.81, p = 0.02)), price sensitivity (demand was lower where SWEs had high prices (r s = -0.65, p = 0.08)), and production cost (water utility tariffs negatively impacted SWE profits (r s = -0.52, p Future research is needed to assess the extent to which kiosk revenue can support ongoing operational costs of WTS and kiosks both at HCF and in other contexts.

The 'SILOE' reactor at Grenoble, France and associated hot cell facilities. Information sheets

International Nuclear Information System (INIS)

Hardt, P. von der; Roettger, H.

1981-01-01

Technical information is given on the SILOE reactor and associated hot cell facilities, with the main emphasis on experimental irradiation facilities, specialized irradiation devices (loops and capsules) and possibilities for post-irradiation examinations of samples. The information is presented in the form of eight information sheets under the headings: main characteristics of the reactor; utilization and specialization of the reactor; experimental facilities; neutron spectra; main characteristics of specialized irradiation devices; main characteristics of hot cell facilities; equipment and techniques available for post-irradiation examinations; utilization and specialization of the hot cell facilities

The 'OSIRIS' reactor at Saclay, France and available hot cell facilities. Information sheets

International Nuclear Information System (INIS)

Hardt, P. von der; Roettger, H.

1981-01-01

Technical information is given on the OSIRIS reactor and associated hot cell facilities, with the main emphasis on experimental irradiation facilities, specialized irradiation devices (loops and capsules) and possibilities for post-irradiation examinations of samples. The information is presented in the form of eight information sheets under the headings: main characteristics of the reactor; utilization and specialization of the reactor; experimental facilities; neutron spectra; main characteristics of specialized irradiation devices; main characteristics of hot cell facilities; equipment and techniques available for post-irradiation examinations; utilization and specialization of the hot cell facilities

Decommissioning of the Risoe Hot Cell facility

International Nuclear Information System (INIS)

Carlsen, H.

1991-02-01

The Hot Cell facility at Risoe has been in active use since 1964. During the years several types of nuclear fuels have been handled and examined: test reactor fuel pins from the Danish reactor DR3, the Norwegian Halden reactor, etc; power reactor fuel pins from several foreign reactors, including plutonium enriched pins; HTGR fuel from the Dragon reactor. All kinds of physical and chemical non-destructive and destructive post irradiation examinations have been performed. Besides, different radiotherapy sources have been produced, mainly cobalt sources. The general object of the decommissioning programme for the Hot Cell facility was to obtain a safe condition for the total building that does not require the special safety provisions. The hot cell building will be usable for other purposes after decommissioning. The facilicy comprised six concrete cells, lead cells, glove boxes, a shielded unit for temporary storage of waste, frogman area, decontamination areas, workshops, various installations of importance for safe operation of the plant, offices, etc. The tasks comprised e.g. removal of all irradiated fuel items, removal of other radioactive items, removal of contaminated equipment, and decontamination of all the cells and rooms. The goal was to decontaminate all the concrete cells to a degree where no loose contamination exists in the cells, and where the radiation level is so low, that total removal of the cell structures can be done at any time in the future without significant dose commitments. (AB)

The ITER EC H and CD Upper Launcher: Maintenance concepts

International Nuclear Information System (INIS)

Ronden, D.M.S.; Baar, M. de; Chavan, R.; Elzendoorn, B.S.Q.; Grossetti, G.; Heemskerk, C.J.M.; Koning, J.F.; Landis, J.-D.; Spaeh, P.; Strauss, D.

2013-01-01

Highlights: ► We explain how an overall maintenance strategy defines individual maintenance tasks. ► Concepts are presented for replacement strategies of the in-vessel optical components. ► Vertical placement of the Upper Launcher in the Hot Cell may simplify maintenance. -- Abstract: Maintenance of the ITER EC H and CD Upper Launcher (UL) shall be performed through the use of Remote Handling (RH) in the ITER Hot Cell Facility (HCF). The UL design will have to be fully compliant with ITER RH maintenance requirements and the set of RH tooling and services available in the HCF. This paper describes the development of an overall maintenance strategy for the UL, starting from a listing of all conceivable maintenance operations, including hands-on tasks. Components for which design concepts are discussed in this paper are the Blanket Shield Module (BSM), the steering mirror (M4), the mid optics (M1, M2) and the waveguide (WG) feed-through plate. Aspects related to RH documentation, overall maintenance strategy and design concepts for optimizing the maintainability of the UL are presented

324 Facility B-Cell quality process plan

International Nuclear Information System (INIS)

Carlson, J.L.

1998-01-01

This report documents the quality process plan for the restart of a hot cell in the B Plant, originally a bismuth phosphate processing facility, but later converted to a waste fractionation plant. B-Cell is currently being cleaned out and deactivated. TPA Milestone M-89-02 dictates that all mixed waste and equipment be removed from B-Cell by 5/31/1999. This report describes the major activities that remain for completion of the TPA milestone

Barriers and challenges in adopting Saudi telemedicine network: The perceptions of decision makers of healthcare facilities in Saudi Arabia.

Science.gov (United States)

Alaboudi, Abdulellah; Atkins, Anthony; Sharp, Bernadette; Balkhair, Ahmed; Alzahrani, Mohammed; Sunbul, Tamara

Despite emerging evidence about the benefits of telemedicine, there are still many barriers and challenges to its adoption. Its adoption is often cited as a failed project because 75% of them are abandoned or 'failed outright' and this percentage increases to 90% in developing countries. The literature has clarified that there is neither one-size-fit-all framework nor best-practice solution for all ICT innovations or for all countries. Barriers and challenges in adopting and implementing one ICT innovation in a given country/organisation may not be similar - not for the same ICT innovation in another country/organisation nor for another ICT innovation in the same country/organisation. To the best of our knowledge, no comprehensive scientific study has investigated these challenges and barriers in all Healthcare Facilities (HCFs) across the Kingdom of Saudi Arabia (KSA). This research, which is undertaken based on the Saudi Telemedicine Network roadmap and in collaboration with the Saudi Ministry of Health (MOH), is aimed at identifying the principle predictive challenges and barriers in the context of the KSA, and understanding the perspective of the decision makers of each HCF type, sector, and location. Three theories are used to underpin this research: the Unified Theory of Acceptance and Use of Technology (UTAUT), the Technology-Organisation-Environment (TOE) theoretical framework, and the Evaluating Telemedicine Systems Success Model (ETSSM). This study applies a three-sequential-phase approach by using three mixed methods (i.e., literature review, interviews, and questionnaires) in order to utilise the source triangulation and the data comparison analysis technique. The findings of this study show that the top three influential barriers to adopt and implement telemedicine by the HCF decision makers are: (i) the availability of adequate sustainable financial support to implement, operate, and maintain the telemedicine system, (ii) ensuring conformity of

Barriers and challenges in adopting Saudi telemedicine network: The perceptions of decision makers of healthcare facilities in Saudi Arabia

Directory of Open Access Journals (Sweden)

Abdulellah Alaboudi

2016-11-01

Full Text Available Summary: Despite emerging evidence about the benefits of telemedicine, there are still many barriers and challenges to its adoption. Its adoption is often cited as a failed project because 75% of them are abandoned or ‘failed outright’ and this percentage increases to 90% in developing countries. The literature has clarified that there is neither one-size-fit-all framework nor best-practice solution for all ICT innovations or for all countries. Barriers and challenges in adopting and implementing one ICT innovation in a given country/organisation may not be similar – not for the same ICT innovation in another country/organisation nor for another ICT innovation in the same country/organisation.To the best of our knowledge, no comprehensive scientific study has investigated these challenges and barriers in all Healthcare Facilities (HCFs across the Kingdom of Saudi Arabia (KSA. This research, which is undertaken based on the Saudi Telemedicine Network roadmap and in collaboration with the Saudi Ministry of Health (MOH, is aimed at identifying the principle predictive challenges and barriers in the context of the KSA, and understanding the perspective of the decision makers of each HCF type, sector, and location. Three theories are used to underpin this research: the Unified Theory of Acceptance and Use of Technology (UTAUT, the Technology–Organisation–Environment (TOE theoretical framework, and the Evaluating Telemedicine Systems Success Model (ETSSM. This study applies a three-sequential-phase approach by using three mixed methods (i.e., literature review, interviews, and questionnaires in order to utilise the source triangulation and the data comparison analysis technique. The findings of this study show that the top three influential barriers to adopt and implement telemedicine by the HCF decision makers are: (i the availability of adequate sustainable financial support to implement, operate, and maintain the telemedicine system, (ii

Proteomic analysis of the herpes simplex virus 1 virion protein 16 transactivator protein in infected cells.

Science.gov (United States)

Suk, Hyung; Knipe, David M

2015-06-01

The herpes simplex virus 1 virion protein 16 (VP16) tegument protein forms a transactivation complex with the cellular proteins host cell factor 1 (HCF-1) and octamer-binding transcription factor 1 (Oct-1) upon entry into the host cell. VP16 has also been shown to interact with a number of virion tegument proteins and viral glycoprotein H to promote viral assembly, but no comprehensive study of the VP16 proteome has been performed at early times postinfection. We therefore performed a proteomic analysis of VP16-interacting proteins at 3 h postinfection. We confirmed the interaction of VP16 with HCF-1 and a large number of cellular Mediator complex proteins, but most surprisingly, we found that the major viral protein associating with VP16 is the infected cell protein 4 (ICP4) immediate-early (IE) transactivator protein. These results raise the potential for a new function for VP16 in associating with the IE ICP4 and playing a role in transactivation of early and late gene expression, in addition to its well-documented function in transactivation of IE gene expression. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Upgrades of Hanford Engineering Development Laboratory hot cell facilities

International Nuclear Information System (INIS)

Daubert, R.L.; DesChane, D.J.

1987-01-01

The Hanford Engineering Development Laboratory operates the 327 Postirradiation Testing Laboratory (PITL) and the 324 Shielded Materials Facility (SMF). These hot cell facilities provide diverse capabilities for the postirradiation examination and testing of irradiated reactor fuels and materials. The primary function of these facilities is to determine failure mechanisms and effects of irradiation on physical and mechanical properties of reactor components. The purpose of this paper is to review major equipment and facility upgrades that enhance customer satisfaction and broaden the engineering capabilities for more diversified programs. These facility and system upgrades are providing higher quality remote nondestructive and destructive examination services with increased productivity, operator comfort, and customer satisfaction

The DIDO-reactor at Harwell, U.K. and ancillary hot cell facilities. Information sheets

International Nuclear Information System (INIS)

Hardt, P. von der; Roettger, H.

1981-01-01

Technical information is given on the DIDO reactor and associated hot cell facilities, with the main emphasis on experimental irradiation facilities, specialized irradiation devices (loops and capsules) and possibilities for post-irradiation examinations of samples. The information is presented in the form of eight information sheets under the headings: main characteristics of the reactor; utilization and specialization of the reactor; experimental facilities; neutron spectra; main characteristics of specialized irradiation devices; main characteristics of hot cell facilities; equipment and techniques available for post-irradiation examinations; utilization and specialization of the hot cell facilities

Safety evaluation report of hot cell facilities for demonstration of advanced spent fuel conditioning process

International Nuclear Information System (INIS)

You, Gil Sung; Choung, W. M.; Ku, J. H.; Cho, I. J.; Kook, D. H.; Park, S. W.; Bek, S. Y.; Lee, E. P.

2004-10-01

The advanced spent fuel conditioning process(ACP) proposed to reduce the overall volume of the PWR spent fuel and improve safety and economy of the long-term storage of spent fuel. In the next phase(2004∼2006), the hot test will be carried out for verification of the ACP in a laboratory scale. For the hot test, the hot cell facilities of α- type and auxiliary facilities are required essentially for safe handling of high radioactive materials. As the hot cell facilities for demonstration of the ACP, a existing hot cell of β- type will be refurbished to minimize construction expenditures of hot cell facility. Up to now, the detail design of hot cell facilities and process were completed, and the safety analysis was performed to substantiate secure of conservative safety. The design data were submitted for licensing which was necessary for construction and operation of hot cell facilities. The safety investigation of KINS on hot cell facilities was completed, and the license for construction and operation of hot cell facilities was acquired already from MOST. In this report, the safety analysis report submitted to KINS was summarized. And also, the questionnaires issued from KINS and answers of KAERI in process of safety investigation were described in detail

The 'MELUSINE' reactor at Grenoble, France, and associated hot cell facilities. Information sheets

International Nuclear Information System (INIS)

Hardt, P. von der; Roettger, H.

1981-01-01

Technical information is given on the MELUSINE reactor and associated hot cell facilities, with the main emphasis on experimental irradiation facilities and specialized irradiation devices (loops and capsules). The information is presented in the form of six information sheets under the headings: main characteristics of the reactor; utilization and specialization of the reactor; experimental facilities; neutron spectra; main characteristics of specialized irradiation devices; main characteristics of hot cell facilities

A green synthetic strategy of nickel hexacyanoferrate nanoparticals supported on the graphene substrate and its non-enzymatic amperometric sensing application

Energy Technology Data Exchange (ETDEWEB)

Xue, Zhonghua, E-mail: xzh@nwnu.edu.cn [Key Laboratory of Bioelectrochemistry & Environmental Analysis of Gansu Province, College of Chemistry & Chemical Engineering, Northwest Normal University, Lanzhou 730070 (China); He, Nan [Key Laboratory of Bioelectrochemistry & Environmental Analysis of Gansu Province, College of Chemistry & Chemical Engineering, Northwest Normal University, Lanzhou 730070 (China); Rao, Honghong [College of Chemistry and Chemical Engineering, Lanzhou City University, Lanzhou, 730070 (China); Hu, Chenxian; Wang, Xiaofen; Wang, Hui; Liu, Xiuhui [Key Laboratory of Bioelectrochemistry & Environmental Analysis of Gansu Province, College of Chemistry & Chemical Engineering, Northwest Normal University, Lanzhou 730070 (China); Lu, Xiaoquan, E-mail: luxq@nwnu.edu.cn [Key Laboratory of Bioelectrochemistry & Environmental Analysis of Gansu Province, College of Chemistry & Chemical Engineering, Northwest Normal University, Lanzhou 730070 (China)

2017-02-28

Highlights: • A sensitive non-enzymatic glucose sensor was explored by using a facile and green strategy. • Well dispersed and uniform NiHCF nanoparticles can be effectively produced by the introduction of electrochemical reduction graphene oxide films. • Metal hexacyanoferrate as a potential electron mediator was proposed and applied into non-enzymatic sensing. - Abstract: Rapid glucose detection is a key requirement for both diagnosis and treatment of diabetes. A facile and green strategy to achieve spherical-shaped nickel hexacyanoferrate (NiHCF) nanoparticals supported on electrochemical reduction graphene oxide by using electrochemical cyclic voltammetry is explored. As a sensing substrate, electrochemical reduction graphene oxide deposited on a glassy carbon electrode surface exhibited obvious positive effect on the electrodeposition of NiHCF nanoparticals with spherical structure and thus effectively improved the electrical conductivity and electrochemical sensing of the proposed amperometric sensor. Proof-concept experiments demonstrated that the proposed nanocomposites modified electrode exhibited excellent sensitivity toward glucose oxidation as well as with a satisfying detection limit of 0.11 μM. More importantly, we also explore that as a simple, green and facile method, electrochemical technology can be employed and provide a new strategy for developing GO and metal hexacyanoferrate based amperometric sensing platform toward glucose and other biomolecules.

A green synthetic strategy of nickel hexacyanoferrate nanoparticals supported on the graphene substrate and its non-enzymatic amperometric sensing application

International Nuclear Information System (INIS)

Xue, Zhonghua; He, Nan; Rao, Honghong; Hu, Chenxian; Wang, Xiaofen; Wang, Hui; Liu, Xiuhui; Lu, Xiaoquan

2017-01-01

Highlights: • A sensitive non-enzymatic glucose sensor was explored by using a facile and green strategy. • Well dispersed and uniform NiHCF nanoparticles can be effectively produced by the introduction of electrochemical reduction graphene oxide films. • Metal hexacyanoferrate as a potential electron mediator was proposed and applied into non-enzymatic sensing. - Abstract: Rapid glucose detection is a key requirement for both diagnosis and treatment of diabetes. A facile and green strategy to achieve spherical-shaped nickel hexacyanoferrate (NiHCF) nanoparticals supported on electrochemical reduction graphene oxide by using electrochemical cyclic voltammetry is explored. As a sensing substrate, electrochemical reduction graphene oxide deposited on a glassy carbon electrode surface exhibited obvious positive effect on the electrodeposition of NiHCF nanoparticals with spherical structure and thus effectively improved the electrical conductivity and electrochemical sensing of the proposed amperometric sensor. Proof-concept experiments demonstrated that the proposed nanocomposites modified electrode exhibited excellent sensitivity toward glucose oxidation as well as with a satisfying detection limit of 0.11 μM. More importantly, we also explore that as a simple, green and facile method, electrochemical technology can be employed and provide a new strategy for developing GO and metal hexacyanoferrate based amperometric sensing platform toward glucose and other biomolecules.

Decommissioning of the Risoe Hot Cell facility

International Nuclear Information System (INIS)

Carlsen, H.

1994-02-01

Concise description of progress in hot cell facility decommissioning at Risoe National Laboratory is presented. Removal of the large contaminated equipment has been completed, all the concrete cells have been finally cleaned. The total contamination left on the concrete walls is of the order of 1850 GBq. Preliminary smear tests proved the stack to be probably clean. The delay in project completion seems to be around 7 months, the remaining work being of rather conventional character. (EG)

Decommissioning of the Risoe Hot Cell facility

International Nuclear Information System (INIS)

Carlsen, H.

1991-08-01

Concise descriptions of actions taken in relation to the decommissioning of the hot cell facility at Risoe National Laboratory are presented. The removal of fissile material, removal and decontamination of large cell internals, and of large equipment such as glove boxes and steel boxes, in addition to dose commitments, are explained. Tables illustrating the analysis of smear tests, constants for contamination level examination, contamination and radiation levels after cleaning and total contamination versus measured radiation are included. (AB)

DWPF remotable television and cell lighting facilities

International Nuclear Information System (INIS)

Heckendorn, F.M. II.

1984-01-01

The Defense Waste Processing Facility (DWPF) for radioactive waste vitrification at the Savannah River Plant (SRP) is now under construction. Development of specialized low cost television (TV) viewing equipment for in-cell and within-melter applications is now complete. High resolution TV cameras not originally designed for high radiation environments have been demonstrated in crane remotable packages to be well suited to the DWPF. High intensity in-cell lighting has also been demonstrated in crane remotable assemblies. These dual 1000 W units (2000 W total) are used to support the multiplicity of TV and cell window viewing requirements. 8 figures

The DR 3 reactor at Risoe, Denmark and its associated hot cell facilities. Information sheets

International Nuclear Information System (INIS)

Hardt, P. von der; Roettger, H.

1981-01-01

Technical information is given on the DR 2 reactor and associated hot cell facilities, with the main emphasis on experimental irradiation facilities, specialized irradiation devices (loops and capsules) and possibilities for post-irradiation examinations of samples. The information is presented in the form of seven information sheets under the headings: main characteristics of the reactor; utilization and specialization of the reactor; experimental facilities; main characteristics of specialized irradiation devices; main characteristics of hot cell facilities; equipment and techniques available for post-irradiation examinations; utilization and specialization of the hot cell facilities

Qualification of academic facilities for small-scale automated manufacture of autologous cell-based products.

Science.gov (United States)

Hourd, Paul; Chandra, Amit; Alvey, David; Ginty, Patrick; McCall, Mark; Ratcliffe, Elizabeth; Rayment, Erin; Williams, David J

2014-01-01

Academic centers, hospitals and small companies, as typical development settings for UK regenerative medicine assets, are significant contributors to the development of autologous cell-based therapies. Often lacking the appropriate funding, quality assurance heritage or specialist regulatory expertise, qualifying aseptic cell processing facilities for GMP compliance is a significant challenge. The qualification of a new Cell Therapy Manufacturing Facility with automated processing capability, the first of its kind in a UK academic setting, provides a unique demonstrator for the qualification of small-scale, automated facilities for GMP-compliant manufacture of autologous cell-based products in these settings. This paper shares our experiences in qualifying the Cell Therapy Manufacturing Facility, focusing on our approach to streamlining the qualification effort, the challenges, project delays and inefficiencies we encountered, and the subsequent lessons learned.

Preliminary Feasibility Study on the Construction of Steel Hot Cell Facility for Precise Manipulated Examinations

International Nuclear Information System (INIS)

Ahn, Sangbok; Kwon, Hyungmun; Kim, Heemoon; Kim, Dosik; Min, Duckkee; Hong, Kwonpyo

2006-01-01

Hot laboratory is essential facility to research and develop in the nuclear industries to examine radioactive materials. The post irradiation examinations for irradiated fuels and materials should be mainly conducted in the hot cell facility to protect radiations to operators. Hot cells are divided into a concrete hot cell and a steel hot cell according to the wall materials. Usually a concrete hot cell is applied to test for high level radioactive materials like as a fuel assembly, rods, and large structure specimens, and a steel hot cell for comparatively lower level activity materials in fuel fragments, and small structural materials. A steel hot cell has many benefits in a specimen manipulation, construction and maintenance costs. In recent the test for the irradiated materials is more frequently required a small and precise manipulating examination for higher degree tests of research and developments. Unfortunately hot laboratory facilities in domestics have mainly constituted of concrete hot cells, and not ready for techniques in steel hot cells. In this paper the construction feasibility of steel hot cell facility is preliminary reviewed in the points of the status of domestic facilities, the test demand prospect and detailed plans

Prospects of using synchrotron radiation facilities with diamond-anvil cells

International Nuclear Information System (INIS)

Manghani, M.H.; Ming, L.C.; Jamieson, J.C.

1980-01-01

Diamond-anvil pressure cells have proven versatile and useful for conducting high pressure research in the submegabar range. The interfacing of diamond-anvil cell technology with synchrotron facilities seems a logical new step for carrying out in situ X-ray diffraction studies of materials under extreme conditions of combined high pressure and temperature. The conventional film method of X-ray diffraction has definite limitations which call for the energy dispersive analysis techniques. Various potential high pressure-temperature studies in geophysis and related fields involving the use of diamond-anvil cell, synchrotron facilities and energy dispersive techniques are exemplified. For geophysical studies the conditions prevailing in 86% of the Earth's volume are capable of being simulated completely in pressure, and partially in pressure and temperature, simultaneously. (orig.)

PSA Solar furnace: A facility for testing PV cells under concentrated solar radiation

Energy Technology Data Exchange (ETDEWEB)

Fernandez-Reche, J.; Canadas, I.; Sanchez, M.; Ballestrin, J.; Yebra, L.; Monterreal, R.; Rodriguez, J.; Garcia, G. [Concentration Solar Technologies, Plataforma Solar de Almeria-CIEMAT P.O. Box 22, Tabernas, E-04200 (Almeria) (Spain); Alonso, M.; Chenlo, F. [Photovoltaic Components and Systems, Renewable Energies Department-CIEMAT Avda. Complutense, 22, Madrid, E-28040 (Spain)

2006-09-22

The Plataforma Solar de Almeria (PSA), the largest centre for research, development and testing of concentration solar thermal technologies in Europe, has started to apply its knowledge, facilities and resources to development of the Concentration PV technology in an EU-funded project HiConPV. A facility for testing PV cells under solar radiation concentrated up to 2000x has recently been completed. The advantages of this facility are that, since it is illuminated by solar radiation, it is possible to obtain the appropriate cell spectral response directly, and the flash tests can be combined with prolonged PV-cell irradiation on large surfaces (up to 150cm{sup 2}), so the thermal response of the PV cell can be evaluated simultaneously. (author)

Small Water Enterprise in Rural Rwanda: Business Development and Year-One Performance Evaluation of Nine Water Kiosks at Health Care Facilities

Directory of Open Access Journals (Sweden)

Alexandra Huttinger

2017-12-01

Full Text Available Small water enterprises (SWEs have lower capital expenditures than centralized systems, offering decentralized solutions for rural markets. This study evaluated SWEs in rural Rwanda, where nine health care facilities (HCF owned and operated water kiosks supplying water from onsite water treatment systems (WTS. SWEs were monitored for 12 months. Spearman’s Rank Correlation Coefficient (rs was used to evaluate correlations between demand for kiosk water and community characteristics, and between kiosk profit and factors influencing the cost model. On average, SWEs distributed 15,300 L/month. One SWE ran at a loss, four had profit margins of ≤10% and four had profit margins of 45–75%. Factors influencing SWE performance were intermittent water supply (87% of SWE closures were due to water shortage, consumer demand (demand was high where populations already used improved water sources (rs = 0.81, p = 0.02, price sensitivity (demand was lower where SWEs had high prices (rs = −0.65, p = 0.08, and production cost (water utility tariffs negatively impacted SWE profits (rs = −0.52, p < 0.01. Sustainability was more favorable in circumstances where recovery of capital expenditures was not expected, and the demand for treated water was sufficient to fund operational expenditures. Future research is needed to assess the extent to which kiosk revenue can support ongoing operational costs of WTS and kiosks both at HCF and in other contexts.

Introduction of hot cell facility in research center Rez - Poster

International Nuclear Information System (INIS)

Petrickova, A.; Srba, O.; Miklos, M.; Svoboda, P.

2015-01-01

This poster presents the hot cell facility which is being constructed as part of the SUSEN project at the Rez research center (Czech Republic). Within this project a new complex of 10 hot cells and one semi-hot cell will be built. There will be 8 gamma hot cells and 2 alpha hot cells. In each hot cell a hermetic, removable box made of stainless steel will home different type of devices. The hot cells and semi hot cell will be equipped with devices for processing samples (cutting, welding, drilling, machining) as well as equipment for testing (sample preparation area, stress testing machine, fatigue machine, electromechanical creep machine, high frequency resonance pulsator...) and equipment for studying material microstructure (nano-indenter with nano-scratch tester and scanning electron microscope). An autoclave with water loop, installed in a cell will allow mechanical testing in control environment of water, pressure and temperature. A scheme shows the equipment of each cell. This hot laboratory will be able to cover all the process to study radioactive materials: receiving the material, the preparation of the samples, mechanical testing and microstructure observation. Our hot cells will be close to the research nuclear reactor LVR-15 and new irradiation facility (high irradiation by cobalt source) is planned to be built within the SUSEN project

Reverse microemulsion synthesis of nickel-cobalt hexacyanoferrate/reduced graphene oxide nanocomposites for high-performance supercapacitors and sodium ion batteries

Science.gov (United States)

Qiu, Xiaoming; Liu, Yongchang; Wang, Luning; Fan, Li-Zhen

2018-03-01

Prussian blue analogues with tunable open channels are of fundamental and technological importance for energy storage systems. Herein, a novel facile synthesis of nickel-cobalt hexacyanoferrate/reduced graphene oxide (denoted as Ni-CoHCF/rGO) nanocomposite is realized by a reverse microemulsion method. The very fine Ni-CoHCF nanoparticles (10-20 nm) are homogeneously anchored on the surface of reduced graphene oxide by electrostatic adsorption and reduced graphene oxide is well-separated by Ni-CoHCF particles. Benefiting from the combined advantages of this structure, the Ni-. It CoHCF/rGO nanocomposite can be used as electrodes for both supercapacitors and sodium ion batteries exhibits excellent pseudocapacitve performance in terms of high specific capacitance of 466 F g-1 at 0.2 A g-1 and 350 F g-1 at 10 A g-1, along with high cycling stabilities. As a cathode material for sodium ion batteries, it also demonstrates a high reversible capacity of 118 mAh g-1 at 0.1 A g-1, good rate capability, and superior cycling stability. These results suggest its potential as an efficient electrode for high-performance energy storage and renewable delivery devices.

The FR 2 reactor at Karlsruhe, F.R. Germany and associated hot cell facilities. Information sheets

International Nuclear Information System (INIS)

Hardt, P. von der; Roettger, H.

1981-01-01

Technical information is given on the FR 2 reactor and associated hot cell facilities, specialized irradiation devices (loops and capsules) and possibilities for post-irradiation examinations of samples. The information is presented in the form of eight information sheets under the headings: main characteristics of the reactor; utilization and specialization of the reactor; experimental facilities; neutron spectra; main characteristics of specialized irradiation devices; main characteristics of hot cell facilities; equipment and techniques available for post-irradiation examinations; utilization and specialization of the hot cell facilities

The FRJ 1 reactor (MERLIN) at Juelich, F.R. Germany and associated hot cell facilities. Information sheets

International Nuclear Information System (INIS)

Hardt, P. von der; Roettger, H.

1981-01-01

Technical information is given on the FRJ 1 reactor and associated hot cell facilities, with the main emphasis on experimental irradiation facilities, specialized irradiation devices (loops and capsules) and possibilities for post-irradiation examinations of samples. The information is presented in the form of eight information sheets under the headings: main characteristics of the reactor; utilization and specialization of the reactor; experimental facilities; neutron spectra; main characteristics of specialized irradiation devices; main characteristics of hot cell facilities; equipment and techniques available for post-irradiation examinations; utilization and specialization of the hot cell facilities

What is the impact of water sanitation and hygiene in healthcare facilities on care seeking behaviour and patient satisfaction? A systematic review of the evidence from low-income and middle-income countries

Science.gov (United States)

Cumming, Oliver; Hunter, Paul R

2018-01-01

Patient satisfaction with healthcare has clear implications on service use and health outcomes. Barriers to care seeking are complex and multiple and delays in seeking care are associated with significant morbidity and mortality. We sought to assess the relationship between water, sanitation and hygiene (WASH) provision in healthcare facilities (HCF) and patient satisfaction/care seeking behaviour in low-income and middle-income countries. Pubmed and Medline Ovid were searched using a combination of search terms. 984 papers were retrieved and only 21 had a WASH component warranting inclusion. WASH was not identified as a driver of patient satisfaction but poor WASH provision was associated with significant patient dissatisfaction with infrastructure and quality of care. However, this dissatisfaction was not sufficient to stop patients from seeking care in these poorly served facilities. With specific regard to maternal health services, poor WASH provision was the reason for women choosing home delivery, although providers’ attitudes and interpersonal behaviours were the main drivers of patient dissatisfaction with maternal health services. Patient satisfaction was mainly assessed via questionnaires and studies reported a high risk of courtesy bias, potentially leading to an overestimation of patient satisfaction. Patient satisfaction was also found to be significantly affected by expectation, which was strongly influenced by patients’ socioeconomic status and education. This systematic review also highlighted a paucity of research to describe and evaluate interventions to improve WASH conditions in HCF in low-income setting with a high burden of healthcare-associated infections. Our review suggests that improving WASH conditions will decrease patience dissatisfaction, which may increase care seeking behaviour and improve health outcomes but that more rigorous research is needed. PMID:29765776

Use of lasers at the Los Alamos Hot-Cell Facility

International Nuclear Information System (INIS)

Lazarus, M.E.

1983-01-01

An optical profilometer that uses a Techmet LaserMike scanning, focused, laser-beam, optical micrometer is installed in a remote alpha-gamma containment cell at the Los Alamos Hot-Cell Facility. A hot-cell extension chamber provides the nominal 30-cm (12-in.) working distance required by the LaserMike and, at the same time, keeps the LaserMike components outside the high-radiation-containment environment. This system provides measurement accuracy better than +- 5 μm (0.0002 in.) on diameters between 2 and 13 mm (0.88 and 0.5 in.) at a rate of 33 measurements per second. The Hot-Cell Facility also uses a Korad 20-J-output ruby pulsed laser to drill a hole in reactor-fuel-element cladding to sample fission gas. The laser is then used to reweld the hole so that the fuel element will not be contaminated and may be stored without an alpha-containment barrier. The wall thickness of the fuel elements sampled varies from 0.25 to 0.50 mm (0.010 to 0.020 in.)

Los Alamos Hot-Cell-Facility modifications for examining FFTF fuel pins

International Nuclear Information System (INIS)

Campbell, B.M.; Ledbetter, J.M.

1982-01-01

Commissioned in 1960, the Wing 9 Hot Cell Facility at Los Alamos was recently modified to meet the needs of the 1980s. Because fuel pins from the Fast Flux Test Facility (FFTF) at the Hanford Engineering Development Laboratory (HEDL) are too long for examination in the original hot cells, we modified cells to accommodate longer fuel pins and to provide other capabilities as well. For instance, the T-3 shipping cask now can be opened in an inert atmosphere that can be maintained for all nondestructive and destructive examinations of the fuel pins. The full-length pins are visually examined and photographed, the wire wrap is removed, and fission gas is sampled. After the fuel pin is cropped, a cap is seal-welded on the section containing the fuel column. This section is then transferred to other cells for gamma-scanning, radiography, profilometry, sectioning for metallography, and chemical analysis

Development of the IFJ single ion hit facility for cells irradiation

International Nuclear Information System (INIS)

Veselov, O.; Polak, W.; Ugenskiene, R.; Hajduk, R.; Lebed, K.; Lekki, J.; Horwacik, T.; Dutkiewicz, E.M.; Maranda, S.; Pieprzyca, T.; Sarnecki, C.; Stachura, Z.; Szklarz, Z.; Styczen, J.

2005-12-01

In recent years a single ion hit facility (SIHF) has been constructed at the IFJ ion microprobe. The setup is used for the precise irradiations of living cells by a controlled number of ions. The facility allows investigations in various aspects of biomedical research, such as adaptive response, bystander effect, inverse dose-rate effect, low-dose hypersensitivity, etc. Those investigations have two very important requirements: (i) cells must be examined in their natural state and environment, i.e. without previously being killed, and preferentially, neither fixed nor stained, and (ii) a possibility of automatic irradiation of large number of cells with a computer recognition of their positions must be provided. This work presents some of the crucial features of the off-line and on-line optical systems, including self-developed software responsible for the automatic cell recognition. We also show several tests carried out to determine the efficiency of the whole setup and some segments. In conclusion, the results of our first irradiation measurements performed with living cells are demonstrated. (author)

Plutonium working group report on environmental, safety and health vulnerabilities associated with the department's plutonium storage. Volume II, Appendix B, Part 10: Sandia National Laboratories - New Mexico site assessment team report

International Nuclear Information System (INIS)

1994-09-01

On March 15, 1994, Secretary O'Leary directed the Office of Environment, Safety and Health to conduct an environment, safety and health (ES ampersand H) vulnerability study of plutonium at DOE sites. This report presents Sandia National Laboratories'/New Mexico (SNL/NM) response to that request. Sandia National Laboratories (SNL) is a multi-program laboratory operated for United States Department of Energy(DOE) by Martin Marietta Corporation. The primary mission of Sandia is research and development of nuclear weapons systems for concept to retirement. The laboratory also has extensive programs in nuclear reactor safety, nuclear safeguards, energy research, and microelectronics. The facilities addressed in the SNL/NM Site Assessment include the Hot Cell Facility (HCF), the Annular Core Research Reactor (ACRR), and dedicated on-site nuclear material storage facilities. Also included in the assessment were sealed radiation sources that contain plutonium

Copper and nickel hexacyanoferrate nanostructures with graphene-coated stainless steel sheets for electrochemical supercapacitors

Science.gov (United States)

Wu, Mao-Sung; Lyu, Li-Jyun; Syu, Jhih-Hao

2015-11-01

Copper and nickel hexacyanoferrate (CuHCF and NiHCF) nanostructures featuring three-dimensional open-framework tunnels are prepared using a solution-based coprecipitation process. CuHCF shows superior supercapacitive behavior than the NiHCF, due to the presence of numerous macropores in CuHCF particles for facilitating the transport of electrolyte. Both CuHCF and NiHCF electrodes with stainless steel (SS) substrate tend to lose their electroactivity towards intercalation/deintercalation of hydrated potassium ions owing to the partial corrosion of SS. Formation of a protective and conductive carbon layer in between SS and CuHCF (NiHCF) film is of paramount importance for improving the irreversible loss of electroactivity. Thin and compact graphene (GN) layer without observable holes in its normal plane is the most effective way to suppress the corrosion of SS compared with porous carbon nanotube and activated carbon layers. Specific capacitance of CuHCF electrode with GN layer (CuHCF/GN/SS) reaches 570 F g-1, which is even better than that of CuHCF with Pt substrate (500 F g-1) at 1 A g-1. The CuHCF/GN/SS exhibits high stability with 96% capacitance retention over 1000 cycles, greater than the CuHCF with Pt (75%).

Fast Flux Test Facility interim examination and maintenance cell: Past, present, and future

International Nuclear Information System (INIS)

Vincent, J.R.

1990-09-01

The Fast Flux Test Facility Interim Examination and Maintenance Cell was designed to perform interim examination and/or disassembly of experimental core components for final analysis elsewhere, as well as maintenance of sodium-wetted or neutron-activated internal reactor parts and plant support hardware. The Interim Examination and Maintenance Cell equipment developed and used for the first ten years of operation has been primarily devoted to the disassembly and examination of core component test assemblies. While no major reactor equipment has required remote repair or maintenance, the Interim Examina Examination and Maintenance Cell has served as the remote repair facility for its own in-cell equipment, and several innovative remote repairs have been accomplished. The Interim Examination and Maintenance Cell's demonstrated versatility has shown its capability to support a challenging future. 12 refs., 9 figs

Water, sanitation and hygiene infrastructure and quality in rural healthcare facilities in Rwanda.

Science.gov (United States)

Huttinger, Alexandra; Dreibelbis, Robert; Kayigamba, Felix; Ngabo, Fidel; Mfura, Leodomir; Merryweather, Brittney; Cardon, Amelie; Moe, Christine

2017-08-03

WHO and UNICEF have proposed an action plan to achieve universal water, sanitation and hygiene (WASH) coverage in healthcare facilities (HCFs) by 2030. The WASH targets and indicators for HCFs include: an improved water source on the premises accessible to all users, basic sanitation facilities, a hand washing facility with soap and water at all sanitation facilities and patient care areas. To establish viable targets for WASH in HCFs, investigation beyond 'access' is needed to address the state of WASH infrastructure and service provision. Patient and caregiver use of WASH services is largely unaddressed in previous studies despite being critical for infection control. The state of WASH services used by staff, patients and caregivers was assessed in 17 rural HCFs in Rwanda. Site selection was non-random and predicated upon piped water and power supply. Direct observation and semi-structured interviews assessed drinking water treatment, presence and condition of sanitation facilities, provision of soap and water, and WASH-related maintenance and record keeping. Samples were collected from water sources and treated drinking water containers and analyzed for total coliforms, E. coli, and chlorine residual. Drinking water treatment was reported at 15 of 17 sites. Three of 18 drinking water samples collected met the WHO guideline for free chlorine residual of >0.2 mg/l, 6 of 16 drinking water samples analyzed for total coliforms met the WHO guideline of hygienic condition and accessible to patients. Regular maintenance of WASH infrastructure consisted of cleaning; no HCF had on-site capacity for performing repairs. Quarterly evaluations of HCFs for Rwanda's Performance Based Financing system included WASH indicators. All HCFs met national policies for water access, but WHO guidelines for environmental standards including water quality were not fully satisfied. Access to WASH services at the HCFs differed between staff and patients and caregivers.

The cost of uncomplicated childhood fevers to Kenyan households: implications for reaching international access targets

Directory of Open Access Journals (Sweden)

Noor Abdisalan M

2006-12-01

Full Text Available Abstract Background Fever is the clinical hallmark of malaria disease. The Roll Back Malaria (RBM movement promotes prompt, effective treatment of childhood fevers as a key component to achieving its optimistic mortality reduction goals by 2010. A neglected concern is how communities will access these new medicines promptly and the costs to poor households when they are located in rural areas distant to health services. Methods We assemble data developed between 2001 and 2002 in Kenya to describe treatment choices made by rural households to treat a child's fever and the related costs to households. Using a cost-of-illness approach, we estimate the expected cost of a childhood fever to Kenyan households in 2002. We develop two scenarios to explore how expected costs to households would change if more children were treated at a health care facility with an effective antimalarial within 48 hours of fever onset. Results 30% of uncomplicated fevers were managed at home with modern medicines, 38% were taken to a health care facility (HCF, and 32% were managed at home without the use of modern medicines. Direct household cash expenditures were estimated at $0.44 per fever, while the total expected cost to households (cash and time of an uncomplicated childhood fever is estimated to be $1.91. An estimated mean of 1.42 days of caretaker time devoted to each fever accounts for the majority of household costs of managing fevers. The aggregate cost to Kenyan households of managing uncomplicated childhood fevers was at least $96 million in 2002, equivalent to 1.00% of the Kenyan GDP. Fewer than 8% of all fevers were treated with an antimalarial drug within 24 hours of fever onset, while 17.5% were treated within 48 hours at a HCF. To achieve an increase from 17.5% to 33% of fevers treated with an antimalarial drug within 48 hours at a HCF (Scenario 1, children already being taken to a HCF would need to be taken earlier. Under this scenario, direct cash

Design of the gas cell for the IGISOL facility at ELI-NP

Energy Technology Data Exchange (ETDEWEB)

Constantin, P., E-mail: paul.constantin@eli-np.ro [Extreme Light Infrastructure – Nuclear Physics, “Horia Hulubei” National Institute for Physics and Nuclear Engineering, Str. Reactorului 30, 077125 Bucharest Magurele (Romania); Balabanski, D.L. [Extreme Light Infrastructure – Nuclear Physics, “Horia Hulubei” National Institute for Physics and Nuclear Engineering, Str. Reactorului 30, 077125 Bucharest Magurele (Romania); Anh, L.T. [Extreme Light Infrastructure – Nuclear Physics, “Horia Hulubei” National Institute for Physics and Nuclear Engineering, Str. Reactorului 30, 077125 Bucharest Magurele (Romania); Graduate University of Science and Technology, Vietnam Academy of Science and Technology, Hanoi (Viet Nam); Cuong, P.V. [Extreme Light Infrastructure – Nuclear Physics, “Horia Hulubei” National Institute for Physics and Nuclear Engineering, Str. Reactorului 30, 077125 Bucharest Magurele (Romania); Centre of Nuclear Physics, Institute of Physics, Vietnam Academy of Science and Technology, Hanoi (Viet Nam); Mei, B. [Extreme Light Infrastructure – Nuclear Physics, “Horia Hulubei” National Institute for Physics and Nuclear Engineering, Str. Reactorului 30, 077125 Bucharest Magurele (Romania)

2017-04-15

One of the experimental programs that will be carried out at the Extreme Light Infrastructure – Nuclear Physics (ELI-NP) facility is the production of exotic neutron-rich ion beams in an IGISOL facility via photofission in a stack of actinide targets placed at the center of a cell filled with He gas. Simulations with the Geant4 toolkit were done for the optimization of the target configuration that maximizes the rate of released photofission fragments. The cell geometry is established based on the stopping properties of these fragments. Studies, based on simulations with Geant4 and SIMION 8.1, of the space charge effect and its induced electric field in the gas cell are presented. Estimates of the extraction time and efficiency of the photofission fragments are derived.

New electron beam facility for irradiated plasma facing materials testing in hot cell

International Nuclear Information System (INIS)

Sakamoto, N.; Kawamura, H.; Akiba, M.

1995-01-01

Since plasma facing components such as the first wall and the divertor for the next step fusion reactors are exposed to high heat loads and high energy neutron flux generated by the plasma, it is urgent to develop of plasma facing components which can resist these. Then, we have established electron beam heat facility (open-quotes OHBISclose quotes, Oarai Hot-cell electron Beam Irradiating System) at a hot cell in JMTR (Japan Materials Testing Reactor) hot laboratory in order to estimate thermal shock resistivity of plasma facing materials and heat removal capabilities of divertor elements under steady state heating. In this facility, irradiated plasma facing materials (beryllium, carbon based materials and so on) and divertor elements can be treated. This facility consists of an electron beam unit with the maximum beam power of 50kW and the vacuum vessel. The acceleration voltage and the maximum beam current are 30kV (constant) and 1.7A, respectively. The loading time of electron beam is more than 0.1ms. The shape of vacuum vessel is cylindrical, and the mainly dimensions are 500mm in inner diameter, 1000mm in height. The ultimate vacuum of this vessel is 1 x 10 -4 Pa. At present, the facility for thermal shock test has been established in a hot cell. And performance estimation on the electron beam is being conducted. Presently, the devices for heat loading tests under steady state will be added to this facility

New electron beam facility for irradiated plasma facing materials testing in hot cell

International Nuclear Information System (INIS)

Shimakawa, S.; Akiba, M.; Kawamura, H.

1996-01-01

Since plasma facing components such as the first wall and the divertor for the next step fusion reactors are exposed to high heat loads and high energy neutron flux generated by the plasma, it is urgent to develop plasma facing components which can resist these. We have established electron beam heat facility ('OHBIS', Oarai hot-cell electron beam irradiating system) at a hot cell in JMTR (Japan materials testing reactor) hot laboratory in order to estimate thermal shock resistivity of plasma facing materials and heat removal capabilities of divertor elements under steady state heating. In this facility, irradiated plasma facing materials (beryllium, carbon based materials and so on) and divertor elements can be treated. This facility consists of an electron beam unit with the maximum beam power of 50 kW and the vacuum vessel. The acceleration voltage and the maximum beam current are 30 kV (constant) and 1.7 A, respectively. The loading time of the electron beam is more than 0.1 ms. The shape of vacuum vessel is cylindrical, and the main dimensions are 500 mm in inside diameter, 1000 mm in height. The ultimate vacuum of this vessel is 1 x 10 -4 Pa. At present, the facility for the thermal shock test has been established in a hot cell. The performance of the electron beam is being evaluated at this time. In the future, the equipment for conducting static heat loadings will be incorporated into the facility. (orig.)

Social engineering: mitigating a stealthy risk.

Science.gov (United States)

Maas, Jos

2014-01-01

Can a Healthcare Facility (HCF) be victimized by Social Engineering (SE)? Yes, says the author If so, what can you do about it? This article explains what Social Engineering is; how it is used; and how to use proactive security to prevent such an attack.

Healing environment: A review of the impact of physical environmental factors on users

NARCIS (Netherlands)

Joost van Hoof; E.R.C.M. Huisman; H.S.M. Kort; E. Morales

2012-01-01

In recent years, the effects of the physical environment on the healing process and well-being have proved to be increasingly relevant for patients and their families (PF) as well as for healthcare staff. The discussions focus on traditional and institutionally designed healthcare facilities (HCF)

PLASMA ELECTRODE POCKELS CELL SUBSYSTEM PERFORMANCE IN THE NATIONAL IGNITION FACILITY

International Nuclear Information System (INIS)

Barbosa, F; Arnold, P; Hinz, A; Zacharias, R; Ollis, C; Fulkerson, E; Mchale, B; Runtal, A; Bishop, C

2007-01-01

The Plasma Electrode Pockels Cell (PEPC) subsystem is a key component of the National Ignition Facility, enabling the laser to employ an efficient four-pass main amplifier architecture. PEPC relies on a pulsed power technology to initiate and maintain plasma within the cells and to provide the necessary high voltage bias to the cells nonlinear crystals. Ultimately, nearly 300 high-voltage, high-current pulse generators will be deployed in the NIF in support of PEPC. Production of solid-state plasma pulse generators and thyratron-switched pulse generators is now complete, with the majority of the hardware deployed in the facility. An entire cluster (one-fourth of a complete NIF) has been commissioned and is operating on a routine basis, supporting laser shot operations. Another cluster has been deployed, awaiting final commissioning. Activation and commissioning of new hardware continues to progress in parallel, driving toward a goal of completing the PEPC subsystem in late 2007

Spent Fuel Handling and Packaging Program: a survey of hot cell facilities

International Nuclear Information System (INIS)

Menon, M.N.

1978-07-01

Hot cell facilities in the United States were surveyed to determine their capabilities for conducting integral fuel assembly and individual fuel rod examinations that are required in support of the Spent Fuel Handling and Packaging Program. The ability to receive, handle, disassemble and reconstitute full-length light water reactor spent fuel assemblies, and the ability to conduct nondestructive and destructive examinations on full-length fuel rods were of particular interest. Three DOE-supported facilities and three commercial facilities were included in the survey. This report provides a summary of the findings

X-ray microbeam stand-alone facility for cultured cells irradiation

Energy Technology Data Exchange (ETDEWEB)

Bożek, Sebastian, E-mail: sebastian.bozek@yahoo.com [Jagiellonian University Medical College, Department of Pharmaceutical Biophysics, Krakow (Poland); Bielecki, Jakub; Wiecheć, Anna; Lekki, Janusz; Stachura, Zbigniew; Pogoda, Katarzyna; Lipiec, Ewelina; Tkocz, Konrad; Kwiatek, Wojciech M. [Institute of Nuclear Physics Polish Academy of Sciences, PL-31342 Krakow (Poland)

2017-03-01

Highlights: • An X-ray microbeam line for irradiation of living cultured cells was constructed. • A step by step explanation of working principles with engineering details, procedures and calculations is presented. • A model of beam and cell interaction is presented. • A method of uniform irradiation of living cells with an exact dose per a cell is presented. • Results of preliminary experiments are presented. - Abstract: The article describes an X-ray microbeam standalone facility dedicated for irradiation of living cultured cells. The article can serve as an advice for such facilities construction, as it begins from engineering details, through mathematical modeling and experimental procedures, ending up with preliminary experimental results and conclusions. The presented system consists of an open type X-ray tube with microfocusing down to about 2 μm, an X-ray focusing system with optical elements arranged in the nested Kirckpatrick-Baez (or Montel) geometry, a sample stand and an optical microscope with a scientific digital CCD camera. For the beam visualisation an X-ray sensitive CCD camera and a spectral detector are used, as well as a scintillator screen combined with the microscope. A method of precise one by one irradiation of previously chosen cells is presented, as well as a fast method of uniform irradiation of a chosen sample area. Mathematical models of beam and cell with calculations of kerma and dose are presented. The experiments on dose-effect relationship, kinetics of DNA double strand breaks repair, as well as micronuclei observation were performed on PC-3 (Prostate Cancer) cultured cells. The cells were seeded and irradiated on Mylar foil, which covered a hole drilled in the Petri dish. DNA lesions were visualised with γ-H2AX marker combined with Alexa Fluor 488 fluorescent dye.

In vitro study of 137Cs sorption by hexacyanoferrates(II)

International Nuclear Information System (INIS)

Nielsen, P.; Dresow, B.; Heinrich, H.C.

1987-01-01

We synthesized a variety of colloidal and non-colloidal mixed hexacyanoferrate(II) complexes of Fe, Cu, Co, Ni, Zn, Mn and studied the cesium sorption in vito under physiological conditions (artificial gastric juice, pH 1.2 and artificial duodenal juice, pH 6.8). All of the hexacyanoferrates under study (except cesium iron(III) hexacyanoferrate CsFeHCF) sorb tracer amounts of 137 Cs quantitatively. Differences in the sorption capacity become obvious by offering substantial amounts of cesium. Potassium copper hexacyanoferrate(II) (KCuHCF) and potassium zinc hexacyanoferrate(II) (KZnHCF) are most efficient in cesium sorption at pH 1.2 and at pH 6.8. The sorption capacities of KCuHCF and KZnHCF (2.3-3.0 mmol Cs/g HCF) are twice as high as for colloidal Prussian blue (KFeHCF; 1.0-1.3 mmol Cs/g HCF) and insoluble Prussian blue (FeHCF; 1.0-1.6 mmol Cs/g HCF). The most promising compounds, KCuHCF and KZnHCF, should be further investigated in in vivo studies for 137/134 cesium decorporation. Evidence indicate that the sorption mechanism for most of the compounds under study is a cesium/potassium ion-exchange reaction. In the case of insoluble Prussian blue (FeHCF), a cesium/proton exchange was observed. On laboratory scale, 137/134 Cs-contaminated whey dry powder, produced from South German cow milk in summer 1986 was almost completely decontaminated by dialysing a whey suspension against buffer solution containing FeHCF. The 137/134 Cs + -ions, completely bound by FeHCF, can be isolated from the buffer solution by simple filtration. The buffer solution and the FeHCF can be re-used several times. (orig.)

FFTF [Fast Flux Test Facility]/IEM [Interim Examination and Maintenance] Cell Fuel Pin Weighing System

International Nuclear Information System (INIS)

Gibbons, P.W.

1987-09-01

A Fuel Pin Weighing Machine has been developed for use in the Fast Flux Test Facility (FFTF) Interim Examination and Maintenance (IEM) Cell to assist in identifying an individual breached fuel pin from its fuel assembly pin bundle. A weighing machine, originally purchased for use in the Fuels and Materials Examination Facility (FMEF) at Hanford, was used as the basis for the IEM Cell system. Design modifications to the original equipment were centered around: 1) adapting the FMEF machine for use in the IEM Cell and 2) correcting operational deficiencies discovered during functional testing in the IEM Cell Mockup

Fast Flux Test Facility interim examination and maintenance cell - past, present, and future

International Nuclear Information System (INIS)

Vincent, J.R.

1990-01-01

The Fast Flux Test Facility (FFTF) interim examination and maintenance (IEM) cell was designed to perform interim examination and/or disassembly of experimental core components for final analysis elsewhere, as well as maintenance of sodium-wetted or neutron-activated internal reactor parts and plant support hardware. The first 10 yr of operation were mainly devoted to the disassembly and examination of core component test assemblies. While some maintenance was performed on reactor support equipment, such as the closed-loop ex-vessel machine (CLEM) sodium-wetted grapple, 90% of IEM cell availability has been devoted to core component tests. Some test assemblies originally considered for processing in the IEM cell have not been irradiated; others, not originally planned, have been designed, irradiated, and processed. While no major reactor equipment has required remote repair or maintenance, the IEM cell has served as the remote repair facility for its own in-cell equipment, and several innovative remote repairs have been accomplished and are described

A green synthetic strategy of nickel hexacyanoferrate nanoparticals supported on the graphene substrate and its non-enzymatic amperometric sensing application

Science.gov (United States)

xue, Zhonghua; He, Nan; Rao, Honghong; Hu, Chenxian; Wang, Xiaofen; Wang, Hui; Liu, Xiuhui; Lu, Xiaoquan

2017-02-01

Rapid glucose detection is a key requirement for both diagnosis and treatment of diabetes. A facile and green strategy to achieve spherical-shaped nickel hexacyanoferrate (NiHCF) nanoparticals supported on electrochemical reduction graphene oxide by using electrochemical cyclic voltammetry is explored. As a sensing substrate, electrochemical reduction graphene oxide deposited on a glassy carbon electrode surface exhibited obvious positive effect on the electrodeposition of NiHCF nanoparticals with spherical structure and thus effectively improved the electrical conductivity and electrochemical sensing of the proposed amperometric sensor. Proof-concept experiments demonstrated that the proposed nanocomposites modified electrode exhibited excellent sensitivity toward glucose oxidation as well as with a satisfying detection limit of 0.11 μM. More importantly, we also explore that as a simple, green and facile method, electrochemical technology can be employed and provide a new strategy for developing GO and metal hexacyanoferrate based amperometric sensing platform toward glucose and other biomolecules.

In Situ Synthesis of Mn3 O4 Nanoparticles on Hollow Carbon Nanofiber as High-Performance Lithium-Ion Battery Anode.

Science.gov (United States)

Zhang, Dan; Li, Guangshe; Fan, Jianming; Li, Baoyun; Li, Liping

2018-04-26

The practical applications of Mn 3 O 4 in lithium-ion batteries are greatly hindered by fast capacity decay and poor rate performance as a result of significant volume changes and low electrical conductivity. It is believed that the synthesis of nanoscale Mn 3 O 4 combined with carbonaceous matrix will lead to a better electrochemical performance. Herein, a convenient route for the synthesis of Mn 3 O 4 nanoparticles grown in situ on hollow carbon nanofiber (denoted as HCF/Mn 3 O 4 ) is reported. The small size of Mn 3 O 4 particles combined with HCF can significantly alleviate volume changes and electrical conductivity; the strong chemical interactions between HCF and Mn 3 O 4 would improve the reversibility of the conversion reaction for MnO into Mn 3 O 4 and accelerate charge transfer. These features endow the HCF/Mn 3 O 4 composite with superior cycling stability and rate performance if used as the anode for lithium-ion batteries. The composite delivers a high discharge capacity of 835 mA h g -1 after 100 cycles at 200 mA g -1 , and 652 mA h g -1 after 240 cycles at 1000 mA g -1 . Even at 2000 mA g -1 , it still shows a high capacity of 528 mA h g -1 . The facile synthetic method and outstanding electrochemical performance of the as-prepared HCF/Mn 3 O 4 composite make it a promising candidate for a potential anode material for lithium-ion batteries. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

In-cell facility for performing mechanical-property tests on irradiated cladding

International Nuclear Information System (INIS)

Yaggee, F.L.; Haglund, R.C.; Mattas, R.F.

1978-11-01

A new facility was developed for testing cladding sections of LWR fuel rods. This facility and the accompanying test procedures have improved the level of in-cell mechanical-testing capabilities, making them comparable to existing capabilities for unirradiated cladding. The new facility is currently being used to study the susceptibility of irradiated Zircaloy cladding from LWR fuel rods to iodine stress-corrosion cracking. Preliminary testing results indicate a systematic effect of temperature, stress and irradiation on the susceptibility of annealed and stress-relieved Zircaloy-2. Experimental data obtained to date are being used to develop a stress-corrosion cracking model for LWR fuel rod failure. SEM examination of the undisturbed fracture surface of specimens that failed by pinhole leakage provides useful information on crack propagation and morphology

DUPIC facility engineering

Energy Technology Data Exchange (ETDEWEB)

Lee, J S; Choi, J W; Go, W I; Kim, H D; Song, K C; Jeong, I H; Park, H S; Im, C S; Lee, H M; Moon, K H; Hong, K P; Lee, K S; Suh, K S; Kim, E K; Min, D K; Lee, J C; Chun, Y B; Paik, S Y; Lee, E P; Yoo, G S; Kim, Y S; Park, J C

1997-09-01

In the early stage of the project, a comprehensive survey was conducted to identify the feasibility of using available facilities and of interface between those facilities. It was found out that the shielded cell M6 interface between those facilities. It was found out that the shielded cell M6 of IMEF could be used for the main process experiments of DUPIC fuel fabrication in regard to space adequacy, material flow, equipment layout, etc. Based on such examination, a suitable adapter system for material transfer around the M6 cell was engineered. Regarding the PIEF facility, where spent PWR fuel assemblies are stored in an annex pool, disassembly devices in the pool are retrofitted and spent fuel rod cutting and shipping system to the IMEF are designed and built. For acquisition of casks for radioactive material transport between the facilities, some adaptive refurbishment was applied to the available cask (Padirac) based on extensive analysis on safety requirements. A mockup test facility was newly acquired for remote test of DUPIC fuel fabrication process equipment prior to installation in the M6 cell of the IMEF facility. (author). 157 refs., 57 tabs., 65 figs.

DUPIC facility engineering

International Nuclear Information System (INIS)

Lee, J. S.; Choi, J. W.; Go, W. I.; Kim, H. D.; Song, K. C.; Jeong, I. H.; Park, H. S.; Im, C. S.; Lee, H. M.; Moon, K. H.; Hong, K. P.; Lee, K. S.; Suh, K. S.; Kim, E. K.; Min, D. K.; Lee, J. C.; Chun, Y. B.; Paik, S. Y.; Lee, E. P.; Yoo, G. S.; Kim, Y. S.; Park, J. C.

1997-09-01

In the early stage of the project, a comprehensive survey was conducted to identify the feasibility of using available facilities and of interface between those facilities. It was found out that the shielded cell M6 interface between those facilities. It was found out that the shielded cell M6 of IMEF could be used for the main process experiments of DUPIC fuel fabrication in regard to space adequacy, material flow, equipment layout, etc. Based on such examination, a suitable adapter system for material transfer around the M6 cell was engineered. Regarding the PIEF facility, where spent PWR fuel assemblies are stored in an annex pool, disassembly devices in the pool are retrofitted and spent fuel rod cutting and shipping system to the IMEF are designed and built. For acquisition of casks for radioactive material transport between the facilities, some adaptive refurbishment was applied to the available cask (Padirac) based on extensive analysis on safety requirements. A mockup test facility was newly acquired for remote test of DUPIC fuel fabrication process equipment prior to installation in the M6 cell of the IMEF facility. (author). 157 refs., 57 tabs., 65 figs

Process cost and facility considerations in the selection of primary cell culture clarification technology.

Science.gov (United States)

Felo, Michael; Christensen, Brandon; Higgins, John

2013-01-01

The bioreactor volume delineating the selection of primary clarification technology is not always easily defined. Development of a commercial scale process for the manufacture of therapeutic proteins requires scale-up from a few liters to thousands of liters. While the separation techniques used for protein purification are largely conserved across scales, the separation techniques for primary cell culture clarification vary with scale. Process models were developed to compare monoclonal antibody production costs using two cell culture clarification technologies. One process model was created for cell culture clarification by disc stack centrifugation with depth filtration. A second process model was created for clarification by multi-stage depth filtration. Analyses were performed to examine the influence of bioreactor volume, product titer, depth filter capacity, and facility utilization on overall operating costs. At bioreactor volumes 5,000 L, clarification using centrifugation followed by depth filtration offers significant cost savings. For bioreactor volumes of ∼ 2,000 L, clarification costs are similar between depth filtration and centrifugation. At this scale, factors including facility utilization, available capital, ease of process development, implementation timelines, and process performance characterization play an important role in clarification technology selection. In the case study presented, a multi-product facility selected multi-stage depth filtration for cell culture clarification at the 500 and 2,000 L scales of operation. Facility implementation timelines, process development activities, equipment commissioning and validation, scale-up effects, and process robustness are examined. © 2013 American Institute of Chemical Engineers.

Facility for gamma irradiations of cultured cells at low dose rates: design, physical characteristics and functioning

International Nuclear Information System (INIS)

Esposito, Giuseppe; Anello, Pasquale; Pecchia, Ilaria; Tabocchini, Maria Antonella; Campa, Alessandro

2016-01-01

We describe a low dose/dose rate gamma irradiation facility (called LIBIS) for in vitro biological systems, for the exposure, inside a CO_2 cell culture incubator, of cells at a dose rate ranging from few μGy/h to some tens of mGy/h. Three different "1"3"7Cs sources are used, depending on the desired dose rate. The sample is irradiated with a gamma ray beam with a dose rate uniformity of at least 92% and a percentage of primary 662 keV photons greater than 80%. LIBIS complies with high safety standards. - Highlights: • A gamma irradiation facility for chronic exposures of cells was set up at the Istituto Superiore di Sanità. • The dose rate uniformity and the percentage of primary 662 keV photons on the sample are greater than 92% and 80%, respectively. • The GEANT4 code was used to design the facility. • Good agreement between simulation and experimental dose rate measurements has been obtained. • The facility will allow to safely investigate different issues about low dose rate effects on cultured cells.

Facility effluent monitoring plan for the 325 Facility

International Nuclear Information System (INIS)

1998-01-01

The Applied Chemistry Laboratory (325 Facility) houses radiochemistry research, radioanalytical service, radiochemical process development, and hazardous and mixed hazardous waste treatment activities. The laboratories and specialized facilities enable work ranging from that with nonradioactive materials to work with picogram to kilogram quantities of fissionable materials and up to megacurie quantities of other radionuclides. The special facilities include two shielded hot-cell areas that provide for process development or analytical chemistry work with highly radioactive materials, and a waste treatment facility for processing hazardous, mixed, low-level, and transuranic wastes generated by Pacific Northwest Laboratory. Radioactive material storage and usage occur throughout the facility and include a large number of isotopes. This material is in several forms, including solid, liquid, particulate, and gas. Some of these materials are also heated during testing which can produce vapors. The research activities have been assigned to the following activity designations: High-Level Hot Cell, Hazardous Waste Treatment Unit, Waste Form Development, Special Testing Projects, Chemical Process Development, Analytical Hot Cell, and Analytical Chemistry. The following summarizes the airborne and liquid effluents and the results of the Facility Effluent Monitoring Plan (FEMP) determination for the facility. The complete monitoring plan includes characterization of effluent streams, monitoring/sampling design criteria, a description of the monitoring systems and sample analysis, and quality assurance requirements

Operating experience and radiation protection problems in the working of the radio-metallurgy hot cell facilities at BARC

International Nuclear Information System (INIS)

Janardhanan, S.; Watamwar, S.B.; Mehta, S.K.; Pillai, P.M.B.; John, Jacob; Kutty, K.N.

1977-01-01

The Bhabha Atomic Research Centre at Bombay has six hot cell facilities for radiometallurgical investigations of irradiated/failed fuel elements. The hot cell facilities have been provided with certain built-in safety features, a ventilation system, radiation monitoring instruments for various purposes, a centralised air monitoring system and a central panel for display of various alarms. Procedures adopted for radiation protection and contamination control include : (1) radiation leak test for cells and filter efficiency evaluation before cell activation, (2) practices to be followed by frog suit personnel while working in hot cell areas, (3) receipt and handling of irradiated fuel elements, (4) cell filter change operation, (5) checks on high level drains and (6) effluent discharge and waste shipments. Operating experience in the working of these facilities along with radiation accident incidents is described. Data regarding release of activity during normal cell operations, dose rates during various metallurgical operations and personnel exposures are presented. (M.G.B.)

REMOTE IN-CELL SAMPLING IMPROVEMENTS PROGRAM AT THESAVANNAH RIVER SITE (SRS) DEFENSE WASTE PROCESSING FACILITY (DWPF)

International Nuclear Information System (INIS)

Marzolf, A

2007-01-01

Remote Systems Engineering (RSE) of the Savannah River National Lab (SRNL) in combination with the Defense Waste Processing Facility(DWPF) Engineering and Operations has evaluated the existing equipment and processes used in the facility sample cells for 'pulling' samples from the radioactive waste stream and performing equipment in-cell repairs/replacements. RSE has designed and tested equipment for improving remote in-cell sampling evolutions and reducing the time required for in-cell maintenance of existing equipment. The equipment within the present process tank sampling system has been in constant use since the facility start-up over 17 years ago. At present, the method for taking samples within the sample cells produces excessive maintenance and downtime due to frequent failures relative to the sampling station equipment and manipulator. Location and orientation of many sampling stations within the sample cells is not conducive to manipulator operation. The overextension of manipulators required to perform many in-cell operations is a major cause of manipulator failures. To improve sampling operations and reduce downtime due to equipment maintenance, a Portable Sampling Station (PSS), wireless in-cell cameras, and new commercially available sampling technology has been designed, developed and/or adapted and tested. The uniqueness of the design(s), the results of the scoping tests, and the benefits relative to in-cell operation and reduction of waste are presented

The Biochemistry of O-GlcNAc Transferase: Which Functions Make It Essential in Mammalian Cells?

Science.gov (United States)

Levine, Zebulon G; Walker, Suzanne

2016-06-02

O-linked N-acetylglucosamine transferase (OGT) is found in all metazoans and plays an important role in development but at the single-cell level is only essential in dividing mammalian cells. Postmitotic mammalian cells and cells of invertebrates such as Caenorhabditis elegans and Drosophila can survive without copies of OGT. Why OGT is required in dividing mammalian cells but not in other cells remains unknown. OGT has multiple biochemical activities. Beyond its well-known role in adding β-O-GlcNAc to serine and threonine residues of nuclear and cytoplasmic proteins, OGT also acts as a protease in the maturation of the cell cycle regulator host cell factor 1 (HCF-1) and serves as an integral member of several protein complexes, many of them linked to gene expression. In this review, we summarize current understanding of the mechanisms underlying OGT's biochemical activities and address whether known functions of OGT could be related to its essential role in dividing mammalian cells.

Efficient handling of high-level radioactive cell waste in a vitrification facility analytical laboratory

International Nuclear Information System (INIS)

Roberts, D.W.; Collins, K.J.

1998-01-01

The Savannah River Site''s (SRS) Defense Waste Processing Facility (DWPF) near Aiken, South Carolina, is the world''s largest and the United State''s first high level waste vitrification facility. For the past 1.5 years, DWPF has been vitrifying high level radioactive liquid waste left over from the Cold War. The vitrification process involves the stabilization of high level radioactive liquid waste into borosilicate glass. The glass is contained in stainless steel canisters. DWPF has filled more than 200 canisters 3.05 meters (10 feet) long and 0.61 meters (2 foot) diameter. Since operations began at DWPF in March of 1996, high level radioactive solid waste continues to be generated due to operating the facility''s analytical laboratory. The waste is referred to as cell waste and is routinely removed from the analytical laboratories. Through facility design, engineering controls, and administrative controls, DWPF has established efficient methods of handling the high level waste generated in its laboratory facility. These methods have resulted in the prevention of undue radiation exposure, wasted man-hours, expenses due to waste disposal, and the spread of contamination. This level of efficiency was not reached overnight, but it involved the collaboration of Radiological Control Operations and Laboratory personnel working together to devise methods that best benefited the facility. This paper discusses the methods that have been incorporated at DWPF for the handling of cell waste. The objective of this paper is to provide insight to good radiological and safety practices that were incorporated to handle high level radioactive waste in a laboratory setting

Ways to develop the prophylaxis of post-transfusion hemolytic complications

Directory of Open Access Journals (Sweden)

B. B. Bahovadinov

2015-01-01

Full Text Available Post-transfusion hemolytic complications (РНС remain аn urgent рrоblem in medical practice despite the improvement of selecting methods of compatible blood transfusion for patients. The numbеr of РНС remains still high (1 in 6 000 - 29 000 transfusions. Aim: to analyze cases of РНС registered in health care facilities (HCF in the Republic of Tajikistan. Method of investigation. Retrospective analysis of materials of national аnd regional committees оп investigation of РНС cases, histories fro hospital archives. During the period 1989-2014 in health facilities were registered 86 cases of РНС approximately 850 000 doses of red bооd cell transfusions containing blооd components, or 1 in 9418 doses of red blood cell-containing blood components. РНС reasons were: incompatibility of АВО blооd group system - 32 (37,3 %, antigen D of blооd group Rhesus factor system - 34 (39,53 %, according to minor blood group antigens of Rhesus factor and Kell blood group system (С, с, Е, е, К - 16 (18,6 %. In 4 cases (4,6 % the cases of РНС were hemolytic transfusions of erythrocyte-containing bags as а result of improper storage in domestic refrigeration without control of temperature storage. Causes of development 78 out of 86 РНС (90,69 % were HCF doctors' mistakes, 8 (9,31 % - mistakes of health personnel of health facilities departments of blood transfusion аnd regional blооd centers. Reducing the frequency of PHC is impossible without training physicians оn transfusion medicine, introduction of modern methods of phenotyping erythrocyte antigens of recipients and donors оn major transfusion significant blood group antigens the АВО system by direct and cross-over methods, Rhesus (С, с, Е, е, Kell (К of patients requiring multiple transfusions, as well as to girls and women of childbearing age.

Introduction of radiation protection and dosimetry in new hot cell facility in research center Rez

International Nuclear Information System (INIS)

Svrcula, P.; Petrickova, A.; Srba, O.; Miklos, M.; Svoboda, P.

2015-01-01

The purpose of the poster is to present radiation protection and dosimetry in the new hot cell facility being constructed as part of the SUSEN project. The hot cell facility is composed of 10 hot cells and 1 semi-hot cell. All shielding is made from steel, the outer wall shielding has thickness of 500 mm, internal wall between hot cells 300 mm with the possibility to extension to 500 mm. The ceiling shielding has a thickness of 400 mm and the floor shielding is 300 mm wide. Shielded windows allow direct view into the hot cells. Their shielding effect is equivalent to 500 mm of steel. The dimension of the window in the control room is 800 mm x 600 mm with a thickness of 900 mm. All important operating data are collected in the central system of hot cells. The system monitors under-pressure level and temperature in each chamber. If necessary it can directly control the ventilation system. Each hot cell is equipped with dose rate probes. The system also measures and evaluates airborne radioactivity in the building

Investigation of thermal fatigue behavior of thermal barrier coating systems

International Nuclear Information System (INIS)

Zhu Dongming; Miller, R.A.

1997-01-01

In the present study, the mechanisms of fatigue crack initiation and propagation, and of coating failure under thermal loads that simulate those in diesel engines are investigated. Surface cracks initiate early and grow continuously under thermal low cycle fatigue (LCF) and high cycle fatigue (HCF) stresses. It is found that, in the absence of interfacial oxidation, the failure associated with LCF is closely related to coating sintering and creep at high temperatures. Significant LCF and HCF interactions have been observed in the thermal fatigue tests. The fatigue crack growth rate in the ceramic coating strongly depends on the characteristic HCF cycle number, N* HCF which is defined as the number of HCF cycles per LCF cycle. The crack growth rate is increased from 0.36 μm/LCF cycle for a pure LCF test to 2.8 μm/LCF cycle for a combined LCF and HCF test at N* HCF about 20 000. A surface wedging model has been proposed to account for the HCF crack growth in the coating systems. This mechanism predicts that the HCF damage effect increases with heat flux and thus with increasing surface temperature swing, thermal expansion coefficient and elastic modulus of the ceramic coating, as well as with the HCF interacting depth. Good correlation has been found between the analysis and experimental evidence. (orig.)

Functional update of the auxiliary proteins PsbW, PsbY, HCF136, PsbN, TerC and ALB3 in maintenance and assembly of PSII

Directory of Open Access Journals (Sweden)

Magdalena ePlöchinger

2016-04-01

Full Text Available Assembly of Photosystem (PS II in plants has turned out to be a highly complex process which, at least in part, occurs in a sequential order and requires many more auxiliary proteins than subunits present in the complex. Owing to the high evolutionary conservation of the subunit composition and the three-dimensional structure of the PSII complex, most plant factors involved in the biogenesis of PSII originated from cyanobacteria and only rarely evolved de novo. Furthermore, in chloroplasts the initial assembly steps occur in the non-appressed stroma lamellae, whereas the final assembly including the attachment of the major LHCII antenna proteins takes place in the grana regions. The stroma lamellae are also the place where part of PSII repair occurs, which very likely also involves assembly factors. In cyanobacteria initial PSII assembly also occurs in the thylakoid membrane, in so-called thylakoid centres, which are in contact with the plasma membrane. Here, we provide an update on the structures, localisations, topologies, functions, expression and interactions of the low molecular mass PSII subunits PsbY, PsbW and the auxiliary factors HCF136, PsbN, TerC and ALB3, assisting in PSII complex assembly and protein insertion into the thylakoid membrane.

Scientist, Single Cell Analysis Facility | Center for Cancer Research

Science.gov (United States)

The Cancer Research Technology Program (CRTP) develops and implements emerging technology, cancer biology expertise and research capabilities to accomplish NCI research objectives.  The CRTP is an outward-facing, multi-disciplinary hub purposed to enable the external cancer research community and provides dedicated support to NCI’s intramural Center for Cancer Research (CCR).  The dedicated units provide electron microscopy, protein characterization, protein expression, optical microscopy and nextGen sequencing. These research efforts are an integral part of CCR at the Frederick National Laboratory for Cancer Research (FNLCR).  CRTP scientists also work collaboratively with intramural NCI investigators to provide research technologies and expertise. KEY ROLES AND RESPONSIBILITIES We are seeking a highly motivated Scientist II to join the newly established Single Cell Analysis Facility (SCAF) of the Center for Cancer Research (CCR) at NCI. The SCAF will house state of the art single cell sequencing technologies including 10xGenomics Chromium, BD Genomics Rhapsody, DEPPArray, and other emerging single cell technologies. The Scientist: Will interact with close to 200 laboratories within the CCR to design and carry out single cell experiments for cancer research Will work on single cell isolation/preparation from various tissues and cells and related NexGen sequencing library preparation Is expected to author publications in peer reviewed scientific journals

Hot cell renovation in the spent fuel conditioning process facility at the Korea Atomic Energy Research Institute

Energy Technology Data Exchange (ETDEWEB)

Yu, Seung Nam; Lee, Jong Kwang; Park, Byung Suk; Cho, Il Je; Kim, Ki Ho [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

2015-10-15

The advanced spent fuel conditioning process facility (ACPF) of the irradiated materials examination facility (IMEF) at the Korea Atomic Energy Research Institute (KAERI) has been renovated to implement a lab scale electrolytic reduction process for pyroprocessing. The interior and exterior structures of the ACPF hot cell have been modified under the current renovation project for the experimentation of the electrolytic reduction process using spent nuclear fuel. The most important aspect of this renovation was the installation of the argon compartment within the hot cell. For the design and system implementation of the argon compartment system, a full-scale mock-up test and a three-dimensional (3D) simulation test were conducted in advance. The remodeling and repairing of the process cell (M8a), the maintenance cell (M8b), the isolation room, and their utilities were also planned through this simulation to accommodate the designed argon compartment system. Based on the considered refurbishment workflow, previous equipment in the M8 cell, including vessels and pipes, were removed and disposed of successfully after a zoning smear survey and decontamination, and new equipment with advanced functions and specifications were installed in the hot cell. Finally, the operating area and isolation room were also refurbished to meet the requirements of the improved hot cell facility.

Planning, Management and Organizational Aspects of the Decommissioning of a Hot Cell Facility

Energy Technology Data Exchange (ETDEWEB)

Strufe, N. [Danish Decommissioning, Roskilde (Denmark)

2013-08-15

This CRP project document ''Planning, Management and Organizational Aspects in Decommissioning of a Hot Cell Facility'' aims to describe the establishment of a management organization that ensures that the DD Hot Cell Project is properly and safely conducted and that staff members, who are seconded to the project, have a strong feeling of ownership and being an integral part of the project. The objectives of the decommissioning project of the hot cell facility is to decontaminate the facility and to remove items that cannot be decontaminated on site, in order for the entire hot cell building to become useable for other purposes without any radiological restrictions. The project requires proper communication and coordination with all stakeholders on-site, comprehensive work plans and strict control of the individual working areas and operations. A project of this type obviously requires a strong and well managed and coordinated project organization. DD has established a management system - KMS. The purposes of the KMS are twofold. The system aims to secure the fulfilment of the conditions and requirements of quality set by the nuclear authorities. The system also aims to provide the basis for a rational and economically feasible operation with a high level of safety. One of the main lessons learned in this project is clear that is to ensure that the necessary resources are available and the required expertise is allocated timely for the performance of the project(s) a strong coordination and great flexibility within the DD organization is required. This document describes the approach and considerations from the project management point of view. The document initially gives an introduction to the hot cell decommissioning project followed by issues of the general considerations and planning of the project within the DD, including aspects on organisation, quality assurance and coordination. (author)

An electrochemical approach: Switching Structures of rare earth metal Praseodymium hexacyanoferrate and its application to sulfite sensor in Red Wine

International Nuclear Information System (INIS)

Devadas, Balamurugan; Sivakumar, Mani; Chen, Shen Ming; Cheemalapati, Srikanth

2015-01-01

Graphical abstract: Nucleation and growth of PrHCF and its application to sulfite oxidation in wine samples. - Highlights: • Electrochemical synthesis of PrHCF. • Switching structures of PrHCF. • Sulfite electrochemical sensor. • Wide linear range and low limit of detection. • Real sample application. - Abstract: Herein, we report a shape-controlled preparation of Praseodymium hexacyanoferrate (PrHCF) using a simple electrochemical technique. The electrochemically fabricated PrHCF modified glassy carbon electrodes (GCE) shows an excellent electrocatalytic activity towards sulfite oxidation. The morphology of PrHCF particles were controlled by carefully changing various synthesis conditions including electrochemical technique (cyclic voltammetry, amperometry and chemical), cations in the supporting electrolyte (K + , Na + , Li + and H + ), deposition cycles, molar ratio of precursors, and applied potential (-.2,0 and 0.2 V). The morphologies of the PrHCF was elucidated using scanning electron microscopy (SEM). The as-synthesized PrHCF was characterized using X-ray diffraction pattern (XRD), Infra-red (IR) and energy dispersive X-ray spectroscopy (EDX). The electrochemical oxidation of sulfite on PrHCF modified GCE was investigated using cyclic voltammetry (CV) and linear sweep voltammetry (LSV). The sensitivity of the as-developed sulfite sensor was determined to be 0.036 μA μM −1 cm −2 . The low limit of detection was determined to be 2.15 μM. The real time application of PrHCF modified GCE was confirmed through the determination of sulfite from red wine and tap water samples

Research and Development of a PEM Fuel Cell, Hydrogen Reformer, and Vehicle Refueling Facility

Energy Technology Data Exchange (ETDEWEB)

Edward F. Kiczek

2007-08-31

Air Products and Chemicals, Inc. has teamed with Plug Power, Inc. of Latham, NY, and the City of Las Vegas, NV, to develop, design, procure, install and operate an on-site hydrogen generation system, an alternative vehicle refueling system, and a stationary hydrogen fuel cell power plant, located in Las Vegas. The facility will become the benchmark for validating new natural gas-based hydrogen systems, PEM fuel cell power generation systems, and numerous new technologies for the safe and reliable delivery of hydrogen as a fuel to vehicles. Most important, this facility will serve as a demonstration of hydrogen as a safe and clean energy alternative. Las Vegas provides an excellent real-world performance and durability testing environment.

Dose control programme of Hot Cell facility at Isotope Wing

International Nuclear Information System (INIS)

Sapkal, Jyotsna A.; Suresh, Manju; Shreenivas, V.; Amruta, C.T.; Yadav, R.K.B.; Gopalkrishanan, R.K.; Patil, B.N.; Sastry, K.V.S.

2015-01-01

Hot Cell Facility of Board of Radiation Isotope Technology (BRIT) at Radiological Laboratories (RLG) is involved in fabrication of sealed radioisotopes like Cobalt-60, Cesium-137 and Iridium-192 radioisotopes which are widely used for various medical and industrial applications. In the field of Medicine, above radioactive sources are used for treatment procedures such as Teletherapy and Brachytherapy. 192 Ir radioisotope is widely used for industrial radiography particularly for non-destructive testing of welds in steel in the oil and gas industries. In spite of the increased production of these radioisotopes to meet the requirements from medical and industrial sector, the annual Collective Dose for BRIT facility, during 2011-2013 has shown a downward trend. This paper describes in brief the measures adopted by the facility based on the radiological safety inputs provided by Radiation Hazards Control (RHC) Unit of Isotope Wing, RLG for reducing the collective dose during year 2012 and 2013 by nearly 40% of collective dose consumed for year-2011. Strict implementation of the radiological safety measures during handling of radioactive sources, administrative controls and engineered safety measures resulted in lowering of collective dose during year 2011-2013. (author)

Coral calcifying fluid pH dictates response to ocean acidification.

Science.gov (United States)

Holcomb, M; Venn, A A; Tambutté, E; Tambutté, S; Allemand, D; Trotter, J; McCulloch, M

2014-06-06

Ocean acidification driven by rising levels of CO2 impairs calcification, threatening coral reef growth. Predicting how corals respond to CO2 requires a better understanding of how calcification is controlled. Here we show how spatial variations in the pH of the internal calcifying fluid (pHcf) in coral (Stylophora pistillata) colonies correlates with differential sensitivity of calcification to acidification. Coral apexes had the highest pHcf and experienced the smallest changes in pHcf in response to acidification. Lateral growth was associated with lower pHcf and greater changes with acidification. Calcification showed a pattern similar to pHcf, with lateral growth being more strongly affected by acidification than apical. Regulation of pHcf is therefore spatially variable within a coral and critical to determining the sensitivity of calcification to ocean acidification.

Response of human corneal fibroblasts on silk film surface patterns.

Science.gov (United States)

Gil, Eun Seok; Park, Sang-Hyug; Marchant, Jeff; Omenetto, Fiorenzo; Kaplan, David L

2010-06-11

Transparent, biodegradable, mechanically robust, and surface-patterned silk films were evaluated for the effect of surface morphology on human corneal fibroblast (hCF) cell proliferation, orientation, and ECM deposition and alignment. A series of dimensionally different surface groove patterns were prepared from optically graded glass substrates followed by casting poly(dimethylsiloxane) (PDMS) replica molds. The features on the patterned silk films showed an array of asymmetric triangles and displayed 37-342 nm depths and 445-3 582 nm widths. hCF DNA content on all patterned films were not significantly different from that on flat silk films after 4 d in culture. However, the depth and width of the grooves influenced cell alignment, while the depth differences affected cell orientation; overall, deeper and narrower grooves induced more hCF orientation. Over 14 d in culture, cell layers and actin filament organization demonstrated that confluent hCFs and their cytoskeletal filaments were oriented along the direction of the silk film patterned groove axis. Collagen type V and proteoglycans (decorin and biglycan), important markers of corneal stromal tissue, were highly expressed with alignment. Understanding corneal stromal fibroblast responses to surface features on a protein-based biomaterial applicable in vivo for corneal repair potential suggests options to improve corneal tissue mimics. Further, the approaches provide fundamental biomaterial designs useful for bioengineering oriented tissue layers, an endemic feature in most biological tissue structures that lead to critical tissue functions.

Investigation of health care waste management in Binzhou District, China

International Nuclear Information System (INIS)

Ruoyan, Gai; Xu Lingzhong; Li Huijuan; Zhou Chengchao; He Jiangjiang; Yoshihisa, Shirayama; Tang Wei; Chushi, Kuroiwa

2010-01-01

In China, national regulations and standards for health care waste management were implemented in 2003. To investigate the current status of health care waste management at different levels of health care facilities (HCF) after the implementation of these regulations, one tertiary hospital, one secondary hospital, and four primary health care centers from Binzhou District were visited and 145 medical staff members and 24 cleaning personnel were interviewed. Generated medical waste totaled 1.22, 0.77, and 1.17 kg/bed/day in tertiary, secondary, and primary HCF, respectively. The amount of medical waste generated in primary health care centers was much higher than that in secondary hospitals, which may be attributed to general waste being mixed with medical waste. This study found that the level of the HCF, responsibility for medical waste management in departments and wards, educational background and training experience can be factors that determine medical staff members' knowledge of health care waste management policy. Regular training programs and sufficient provision of protective measures are urgently needed to improve occupational safety for cleaning personnel. Financing and administrative monitoring by local authorities is needed to improve handling practices and the implementation of off-site centralized disposal in primary health care centers.

A recoverable gas-cell diagnostic for the National Ignition Facility

Energy Technology Data Exchange (ETDEWEB)

Ratkiewicz, A., E-mail: ratkiewicz1@llnl.gov; Berzak Hopkins, L.; Bleuel, D. L.; Cassata, W. S.; Velsko, C. A.; Yeamans, C. B. [Lawrence Livermore National Laboratory, Livermore, California 95440 (United States); Bernstein, L. A.; Bibber, K. van; Goldblum, B. L. [University of California, Berkeley, California 94720 (United States); Siem, S. [University of Oslo, N-0316 Oslo (Norway); Wiedeking, M. [iThemba LABS, Somerset West 7129 (South Africa)

2016-11-15

The high-fluence neutron spectrum produced by the National Ignition Facility (NIF) provides an opportunity to measure the activation of materials by fast-spectrum neutrons. A new large-volume gas-cell diagnostic has been designed and qualified to measure the activation of gaseous substances at the NIF. This in-chamber diagnostic is recoverable, reusable and has been successfully fielded. Data from the qualification of the diagnostic have been used to benchmark an Monte Carlo N-Particle Transport Code simulation describing the downscattered neutron spectrum seen by the gas cell. We present early results from the use of this diagnostic to measure the activation of {sup nat}Xe and discuss future work to study the strength of interactions between plasma and nuclei.

A recoverable gas-cell diagnostic for the National Ignition Facility.

Science.gov (United States)

Ratkiewicz, A; Berzak Hopkins, L; Bleuel, D L; Bernstein, L A; van Bibber, K; Cassata, W S; Goldblum, B L; Siem, S; Velsko, C A; Wiedeking, M; Yeamans, C B

2016-11-01

The high-fluence neutron spectrum produced by the National Ignition Facility (NIF) provides an opportunity to measure the activation of materials by fast-spectrum neutrons. A new large-volume gas-cell diagnostic has been designed and qualified to measure the activation of gaseous substances at the NIF. This in-chamber diagnostic is recoverable, reusable and has been successfully fielded. Data from the qualification of the diagnostic have been used to benchmark an Monte Carlo N-Particle Transport Code simulation describing the downscattered neutron spectrum seen by the gas cell. We present early results from the use of this diagnostic to measure the activation of nat Xe and discuss future work to study the strength of interactions between plasma and nuclei.

STREAMLINED APPROACH FOR ENVIRONMENTAL RESTORATION PLAN FOR CORRECTIVE ACTION UNIT 116: AREA 25 TEST CELL C FACILITY NEVADA TEST SITE, NEVADA

International Nuclear Information System (INIS)

2006-01-01

This Streamlined Approach for Environmental Restoration Plan identifies the activities required for the closure of Corrective Action Unit 116, Area 25 Test Cell C Facility. The Test Cell C Facility is located in Area 25 of the Nevada Test Site approximately 25 miles northwest of Mercury, Nevada

Enhancing Stability of Perovskite Solar Cells to Moisture by the Facile Hydrophobic Passivation.

Science.gov (United States)

Hwang, Insung; Jeong, Inyoung; Lee, Jinwoo; Ko, Min Jae; Yong, Kijung

2015-08-12

In this study, a novel and facile passivation process for a perovskite solar cell is reported. Poor stability in ambient atmosphere, which is the most critical demerit of a perovskite solar cell, is overcome by a simple passivation process using a hydrophobic polymer layer. Teflon, the hydrophobic polymer, is deposited on the top of a perovskite solar cell by a spin-coating method. With the hydrophobic passivation, the perovskite solar cell shows negligible degradation after a 30 day storage in ambient atmosphere. Suppressed degradation of the perovskite film is proved in various ways: X-ray diffraction, light absorption spectrum, and quartz crystal microbalance. This simple but effective passivation process suggests new kind of approach to enhance stability of perovskite solar cells to moisture.

Preliminary safety analysis report for the Auxiliary Hot Cell Facility, Sandia National Laboratories, Albuquerque, New Mexico

International Nuclear Information System (INIS)

OSCAR, DEBBY S.; WALKER, SHARON ANN; HUNTER, REGINA LEE; WALKER, CHERYL A.

1999-01-01

The Auxiliary Hot Cell Facility (AHCF) at Sandia National Laboratories, New Mexico (SNL/NM) will be a Hazard Category 3 nuclear facility used to characterize, treat, and repackage radioactive and mixed material and waste for reuse, recycling, or ultimate disposal. A significant upgrade to a previous facility, the Temporary Hot Cell, will be implemented to perform this mission. The following major features will be added: a permanent shield wall; eight floor silos; new roof portals in the hot-cell roof; an upgraded ventilation system; and upgraded hot-cell jib crane; and video cameras to record operations and facilitate remote-handled operations. No safety-class systems, structures, and components will be present in the AHCF. There will be five safety-significant SSCs: hot cell structure, permanent shield wall, shield plugs, ventilation system, and HEPA filters. The type and quantity of radionuclides that could be located in the AHCF are defined primarily by SNL/NM's legacy materials, which include radioactive, transuranic, and mixed waste. The risk to the public or the environment presented by the AHCF is minor due to the inventory limitations of the Hazard Category 3 classification. Potential doses at the exclusion boundary are well below the evaluation guidelines of 25 rem. Potential for worker exposure is limited by the passive design features incorporated in the AHCF and by SNL's radiation protection program. There is no potential for exposure of the public to chemical hazards above the Emergency Response Protection Guidelines Level 2

Preliminary safety analysis report for the Auxiliary Hot Cell Facility, Sandia National Laboratories, Albuquerque, New Mexico

Energy Technology Data Exchange (ETDEWEB)

OSCAR,DEBBY S.; WALKER,SHARON ANN; HUNTER,REGINA LEE; WALKER,CHERYL A.

1999-12-01

The Auxiliary Hot Cell Facility (AHCF) at Sandia National Laboratories, New Mexico (SNL/NM) will be a Hazard Category 3 nuclear facility used to characterize, treat, and repackage radioactive and mixed material and waste for reuse, recycling, or ultimate disposal. A significant upgrade to a previous facility, the Temporary Hot Cell, will be implemented to perform this mission. The following major features will be added: a permanent shield wall; eight floor silos; new roof portals in the hot-cell roof; an upgraded ventilation system; and upgraded hot-cell jib crane; and video cameras to record operations and facilitate remote-handled operations. No safety-class systems, structures, and components will be present in the AHCF. There will be five safety-significant SSCs: hot cell structure, permanent shield wall, shield plugs, ventilation system, and HEPA filters. The type and quantity of radionuclides that could be located in the AHCF are defined primarily by SNL/NM's legacy materials, which include radioactive, transuranic, and mixed waste. The risk to the public or the environment presented by the AHCF is minor due to the inventory limitations of the Hazard Category 3 classification. Potential doses at the exclusion boundary are well below the evaluation guidelines of 25 rem. Potential for worker exposure is limited by the passive design features incorporated in the AHCF and by SNL's radiation protection program. There is no potential for exposure of the public to chemical hazards above the Emergency Response Protection Guidelines Level 2.

The remote handling compatibility analysis of the ITER generic upper port plug structure

Energy Technology Data Exchange (ETDEWEB)

Ronden, D.M.S., E-mail: d.m.s.ronden@differ.nl [FOM Institute DIFFER, P.O. Box 1207, 3430 BE Nieuwegein (Netherlands); Dammann, A. [ITER Organization, Route de Vinon sur Verdon, 13115 Saint Paul-lez-Durance (France); Elzendoorn, B. [FOM Institute DIFFER, P.O. Box 1207, 3430 BE Nieuwegein (Netherlands); Giacomin, T. [ITER Organization, Route de Vinon sur Verdon, 13115 Saint Paul-lez-Durance (France); Heemskerk, C. [Heemskerk Innovative Technology, Merelhof 2, 2172 HZ Sassenheim (Netherlands); Loesser, D. [Princeton Plasma Physics Laboratory, Princeton, NJ 08543-0451 (United States); Maquet, P. [ITER Organization, Route de Vinon sur Verdon, 13115 Saint Paul-lez-Durance (France); Oosterhout, J. van [FOM Institute DIFFER, P.O. Box 1207, 3430 BE Nieuwegein (Netherlands); Pak, S.; Pitcher, C.S.; Portales, M.; Proust, M.; Udintsev, V.S.; Walsh, M.J. [ITER Organization, Route de Vinon sur Verdon, 13115 Saint Paul-lez-Durance (France)

2014-10-15

Highlights: • We describe the remote handling compatibility of the ITER generic upper port plug. • Concepts are presented of specific design solutions to improve RH compatibility. • Simulation in VR of the GUPP DSM replacement indicates possible collisions. • Specific tooling concepts are proposed for GUPP handling equipment for the hot cell. - Abstract: The ITER diagnostics generic upper port plug (GUPP) is developed as a standardized design for all diagnostic upper port plugs, in which a variety of payloads can be mounted. Here, the remote handling compatibility analysis (RHCA) of the GUPP design is presented that was performed for the GUPP final design review. The analysis focuses mainly on the insertion and extraction procedure of the diagnostic shield module (DSM), a removable cassette that contains the diagnostic in-vessel components. It is foreseen that the DSM is a replaceable component – the procedure of which is to be performed inside the ITER hot cell facility (HCF), where the GUPP can be oriented in a vertical position. The DSM removal procedure in the HCF consists of removing locking pins, an M30 sized shoulder bolt and two electrical straps through the use of a dexterous manipulator, after which the DSM is lifted out of the GUPP by an overhead crane. For optimum access to its internals, the DSM is mounted in a handling device. The insertion of a new or refurbished DSM follows the reverse procedure. The RHCA shows that the GUPP design requires a moderate amount of changes to become fully compatible with RH maintenance requirements.

The remote handling compatibility analysis of the ITER generic upper port plug structure

International Nuclear Information System (INIS)

Ronden, D.M.S.; Dammann, A.; Elzendoorn, B.; Giacomin, T.; Heemskerk, C.; Loesser, D.; Maquet, P.; Oosterhout, J. van; Pak, S.; Pitcher, C.S.; Portales, M.; Proust, M.; Udintsev, V.S.; Walsh, M.J.

2014-01-01

Highlights: • We describe the remote handling compatibility of the ITER generic upper port plug. • Concepts are presented of specific design solutions to improve RH compatibility. • Simulation in VR of the GUPP DSM replacement indicates possible collisions. • Specific tooling concepts are proposed for GUPP handling equipment for the hot cell. - Abstract: The ITER diagnostics generic upper port plug (GUPP) is developed as a standardized design for all diagnostic upper port plugs, in which a variety of payloads can be mounted. Here, the remote handling compatibility analysis (RHCA) of the GUPP design is presented that was performed for the GUPP final design review. The analysis focuses mainly on the insertion and extraction procedure of the diagnostic shield module (DSM), a removable cassette that contains the diagnostic in-vessel components. It is foreseen that the DSM is a replaceable component – the procedure of which is to be performed inside the ITER hot cell facility (HCF), where the GUPP can be oriented in a vertical position. The DSM removal procedure in the HCF consists of removing locking pins, an M30 sized shoulder bolt and two electrical straps through the use of a dexterous manipulator, after which the DSM is lifted out of the GUPP by an overhead crane. For optimum access to its internals, the DSM is mounted in a handling device. The insertion of a new or refurbished DSM follows the reverse procedure. The RHCA shows that the GUPP design requires a moderate amount of changes to become fully compatible with RH maintenance requirements

Preliminary assessment for dust contamination of ITER In-Vessel Transporter

Energy Technology Data Exchange (ETDEWEB)

Saito, Makiko, E-mail: saito.makiko@jaea.go.jp [Japan Atomic Energy Agency, Fusion Research and Development Directorate, Naka, Ibaraki-ken 311-0193 (Japan); Ueno, Kenichi; Maruyama, Takahito; Murakami, Shin; Takeda, Nobukazu; Kakudate, Satoshi [Japan Atomic Energy Agency, Fusion Research and Development Directorate, Naka, Ibaraki-ken 311-0193 (Japan); Nakahira, Masataka; Tesini, Alessandro [ITER Organization, Route de Vinon sur Verdon, 13115 St Paul Lez Durance (France)

2014-10-15

Highlights: •To assess the exposure to the maintenance workers, we calculated the effective dose rate. •To reduce the effective dose rate, the IVT was decontaminated and underwent a design change. •The effective dose rate at each maintenance point was also calculated. -- Abstract: After plasma operations of ITER, radioactive dust will have accumulated in the vacuum vessel (VV). The In-Vessel Transporter (IVT) will be introduced into the VV to remove the shield blanket modules for maintenance or replacement and later reinstall them. The IVT itself also needs to undergo regular maintenance in the Hot Cell Facility (HCF). It is assumed that maintenance workers will be exposed to radioactive dust that has adhered to the surfaces of the IVT. In this study, the areas of the IVT that may be contaminated by dust are evaluated to assess the level of exposure to workers during maintenance work in the HCF. Decontamination processes for the IVT, such as a combination of vacuuming and brushing, were investigated and the dose rate after these processes was evaluated. Even though dust was removed from surfaces where decontamination was possible, the dose rate was very high at some assessment points. To decrease the dose rate in accordance with ALARA policy, a decontamination plan and a maintenance plan, which includes the removal of dust, a radiation shield system, and a reduction in working time are proposed.

Procuring Stationary Fuel Cells For CHP: A Guide for Federal Facility Decision Makers

Energy Technology Data Exchange (ETDEWEB)

Stinton, David P [ORNL; McGervey, Joseph [SRA International, Inc.; Curran, Scott [ORNL

2011-11-01

Federal agency leaders are expressing growing interest in using innovative fuel cell combined heat and power (CHP) technology at their sites, motivated by both executive branch sustainability targets and a desire to lead by example in the transition to a clean energy economy. Fuel cell CHP can deliver reliable electricity and heat with 70% to 85% efficiency. Implementing this technology can be a high efficiency, clean energy solution for agencies striving to meet ambitious sustainability requirements with limited budgets. Fuel cell CHP systems can use natural gas or renewable fuels, such as biogas. Procuring Stationary Fuel Cells for CHP: A Guide for Federal Facility Decision Makers presents an overview of the process for planning and implementing a fuel cell CHP project in a concise, step-by-step format. This guide is designed to help agency leaders turn their interest in fuel cell technology into successful installations. This guide concentrates on larger (100 kW and greater) fuel cell CHP systems and does not consider other fuel cell applications such as cars, forklifts, backup power supplies or small generators (<100 kW). Because fuel cell technologies are rapidly evolving and have high up front costs, their deployment poses unique challenges. The electrical and thermal output of the CHP system must be integrated with the building s energy systems. Innovative financing mechanisms allow agencies to make a make versus buy decision to maximize savings. This guide outlines methods that federal agencies may use to procure fuel cell CHP systems with little or no capital investment. Each agency and division, however, has its own set of procurement procedures. This guide was written as a starting point, and it defers to the reader s set of rules if differences exist. The fuel cell industry is maturing, and project developers are gaining experience in working with federal agencies. Technology improvements, cost reductions, and experienced project developers are making

Decontamination Project for Cell G of the Metal Recovery Facility at Oak Ridge National Laboratory, Oak Ridge, Tennessee

International Nuclear Information System (INIS)

Mandry, G.J.; Grisham, R.W.

1994-02-01

The goal of the decontamination effort in Cell G at the Metal Recovery Facility, Building 3505, located at the Oak Ridge National Laboratory, was two-fold: to determine the effectiveness of the dry decontamination technique employed and to provide data required to assess whether additional decontamination using this method would be beneficial in the eventual decommissioning of the facility. Allied Technology Group (ATG) was contracted to remove a portion of the concrete surface in Cell G by a technique known as scabbling. Some metallic cell components were also scabbled to remove paint and other surface debris. Generally, the scabbling operation was a success. Levels of contamination were greatly reduced. The depth of contaminant penetration into the concrete surfaces of certain areas was much greater than had been anticipated, necessitating the removal of additional concrete and extending ATG's period of performance. Scabbling and other related techniques will be extremely useful in the decontamination and decommissioning of other nuclear facilities with similar radiological profiles

Gamma Radiation -Induced Preparation of Polymeric Composite Resins and their Structure Assignments

International Nuclear Information System (INIS)

El-Zahhar, A.A.; Abdel-Aziz, H.M.; Siyam, T.

2005-01-01

Poly(acrylamide-acrylic acid). ethylenediamine tetra acetic acid disodium salt P(AM-AA). EDTANa2, Poly(acrylamide-acrylic acid)montmorillonite P(AM-AA). montmorillonite, and Poly(acrylamide acrylic acid)-potassium nickel hexacyanoferrate P(AM-AA)-KNiHCF were prepared by gamma radiation- induced template polymerization of (AA) on P(AM) as a template polymer in the presence of EDTANa2, Clay(montmorillonite), KNiHCF and KZnHCF, respectively. The capacity of the prepared P (AM-AA)-EDTANa2 and P (AM-AA)-montmorillonite composites increases with increasing of EDTANa2 and montmorillonite concentration then decreases. While the capacity of P(AM- AA). KNiHCF composites increases with increasing of KNiHCF content. The characteristic properties of prepared polymeric composites resins were studied by using FTIR spectroscopy

D and D Toolbox Project - Technology Demonstration of Fixatives Applied to Hot Cell Facilities via Remote Sprayer Platforms

International Nuclear Information System (INIS)

Lagos, L.; Shoffner, P.; Espinosa, E.; Pena, G.; Kirk, P.; Conley, T.

2009-01-01

The objective of the US Department of Energy Office of Environmental Management's (DOE-EM's) D and D Toolbox Project is to use an integrated systems approach to develop a suite of decontamination and decommissioning (D and D) technologies, a D and D toolbox, that can be readily used across the DOE complex to improve safety, reduce technical risks, and limit uncertainty within D and D operations. Florida International University's Applied Research Center (FIU-ARC) is supporting this initiative by identifying technologies suitable to meet specific facility D and D requirements, assessing the readiness of those technologies for field deployment, and conducting technology demonstrations of selected technologies at FIU-ARC facilities in Miami, Florida. To meet the technology gap challenge for a technology to remotely apply strippable/fixative coatings, FIU-ARC identified and demonstrated of a remote fixative sprayer platform. During this process, FIU-ARC worked closely with the Oak Ridge National Laboratory in the selection of typical fixatives and in the design of a hot cell mockup facility for demonstrations at FIUARC. For this demonstration and for future demonstrations, FIU-ARC built a hot cell mockup facility at the FIU-ARC Technology Demonstration/Evaluation site in Miami, Florida. FIU-ARC selected the International Climbing Machines' (ICM's) Robotic Climber to perform this technology demonstration. The selected technology was demonstrated at the hot cell mockup facility at FIU-ARC during the week of November 10, 2008. Fixative products typically used inside hot cells were investigated and selected for this remote application. The fixatives tested included Sherwin Williams' Promar 200 and DTM paints and Bartlett's Polymeric Barrier System (PBS). The technology evaluation documented the ability of the remote system to spray fixative products on horizontal and vertical concrete surfaces. The technology performance, cost, and health and safety issues were evaluated

Animal facilities

International Nuclear Information System (INIS)

Fritz, T.E.; Angerman, J.M.; Keenan, W.G.; Linsley, J.G.; Poole, C.M.; Sallese, A.; Simkins, R.C.; Tolle, D.

1981-01-01

The animal facilities in the Division are described. They consist of kennels, animal rooms, service areas, and technical areas (examining rooms, operating rooms, pathology labs, x-ray rooms, and 60 Co exposure facilities). The computer support facility is also described. The advent of the Conversational Monitor System at Argonne has launched a new effort to set up conversational computing and graphics software for users. The existing LS-11 data acquisition systems have been further enhanced and expanded. The divisional radiation facilities include a number of gamma, neutron, and x-ray radiation sources with accompanying areas for related equipment. There are five 60 Co irradiation facilities; a research reactor, Janus, is a source for fission-spectrum neutrons; two other neutron sources in the Chicago area are also available to the staff for cell biology studies. The electron microscope facilities are also described

Three dimensional considerations in thermal-hydraulics of helical cruciform fuel rods for LWR power uprates

Energy Technology Data Exchange (ETDEWEB)

Shirvan, Koroush, E-mail: kshirvan@mit.edu; Kazimi, Mujid S.

2014-04-01

Highlights: • We benchmarked the 4 × 4 helical cruciform fuel (HCF) bundle pressure drop experimental data with CFD. • We also benchmarked the 4 × 4 HCF mixing experimental data with CFD. • We derived new friction factors for PWR and BWR designs at PWR and BWR operating conditions from CFD. • We showed the importance of modeling the 3D conduction in HCF in steady state and transient conditions. - Abstract: In order to increase the power density of current and new light water reactor designs, the helical cruciform fuel (HCF) rods have been proposed. The HCF rod is equivalent to a thin cylindrical rod, with 4 fuel containing vanes, wrapped around it. The HCF rods increase the surface area to volume ratio of the fuel and enhance the inter-subchannel mixing due to their helical shape. The rods do not need supporting grids, as they are packed to periodically contact their neighbors along the flow direction, enabling a higher power density in the core. The HCF rods were reported to have the potential to uprate existing PWRs by 45% and BWRs by 20%. In order to quantify the mixing behavior of the HCF rods based on their twist pitch, experiments were previously performed at atmospheric pressures with single phase water in a 4 by 4 HCF and cylindrical rod bundles. In this paper, the experimental results on pressure drop and mixing are benchmarked with computational fluid dynamic (CFD) using steady state the Reynolds average Navier–Stokes (RANS) turbulence model. The sensitivity of the CFD approach to computational domain, mesh size, mesh shape and RANS turbulence models are examined against the experimental conditions. Due to the refined radial velocity profile from the HCF rods twist, the turbulence models showed little sensitivity to the domain. Based on the CFD simulations, the total pressure drops under the PWR and BWR conditions are expected to be about 10% higher than the values previously reported solely from an empirical correlation based on the

Nickel Hexacyanoferrate Nanoparticles as a Low Cost Cathode Material for Lithium-Ion Batteries

International Nuclear Information System (INIS)

Omarova, Marzhana; Koishybay, Aibolat; Yesibolati, Nulati; Mentbayeva, Almagul; Umirov, Nurzhan; Ismailov, Kairat; Adair, Desmond; Babaa, Moulay-Rachid; Kurmanbayeva, Indira; Bakenov, Zhumabay

2015-01-01

Potassium nickel hexacyanoferrate KNi[Fe(CN) 6 ] (NiHCF) was synthesized by a simple co-precipitation method and investigated as a cathode material for lithium-ion batteries. The X-ray diffraction and transmission electron microscopy studies revealed the formation of pure phase of agglomerated NiHCF nanoparticles of about 20–50 nm in size. The material exhibited stable cycling performance as a cathode in a lithium half-cell within a wide range of current densities, and a working potential around 3.3 V vs. Li + /Li. The lithium ion diffusion coefficient in this system was determined to be in a range of 10 −9 to 10 −8 cm 2 s −1 , which is within the values for the cathode materials for lithium-ion batteries with high rate capability. Considering promising electrochemical performance and attractive lithium-ion diffusion properties of this material along with its economical benefits and simplified preparation, NiHCF could be considered as a very promising cathode for large scale lithium-ion batteries.

DUPIC facility engineering

Energy Technology Data Exchange (ETDEWEB)

Park, J. J.; Lee, H. H.; Kim, K. H. and others

2000-03-01

The objectives of this study are (1) the refurbishment for PIEF(Post Irradiation Examination Facility) and M6 hot-cell in IMEF(Irradiated Material Examination Facility), (2) the establishment of the compatible facility for DUPIC fuel fabrication experiments which is licensed by government organization, and (3) the establishment of the transportation system and transportation cask for nuclear material between facilities. The report for this project describes following contents, such as objectives, necessities, scope, contents, results of current step, R and D plan in future and etc.

Metabolic and cardiac changes in high cholesterol-fructose-fed rats

DEFF Research Database (Denmark)

Axelsen, Lene N; Pedersen, Henrik D; Petersen, Jørgen S

2010-01-01

Introduction: High cholesterol-fructose (HCF) fed rats have previously been described as an animal model of impaired cardiac insulin signaling and decreased contractile performance. In this study, we evaluated the metabolic and cardiac effects of a HCF diet in rats. Methods: Male Sprague-Dawley r......Introduction: High cholesterol-fructose (HCF) fed rats have previously been described as an animal model of impaired cardiac insulin signaling and decreased contractile performance. In this study, we evaluated the metabolic and cardiac effects of a HCF diet in rats. Methods: Male Sprague...

Hot cell renovation in the spent fuel conditioning process facility at the Korea Atomic Energy Research Institute

Directory of Open Access Journals (Sweden)

Seung Nam Yu

2015-10-01

Results and conclusion: Based on the considered refurbishment workflow, previous equipment in the M8 cell, including vessels and pipes, were removed and disposed of successfully after a zoning smear survey and decontamination, and new equipment with advanced functions and specifications were installed in the hot cell. Finally, the operating area and isolation room were also refurbished to meet the requirements of the improved hot cell facility.

Electrochemical synthesis of nickel hexacyanoferrate nanoarrays with dots, rods and nanotubes morphology using a porous alumina template

Energy Technology Data Exchange (ETDEWEB)

Sabzi, Reza Emamali [Department of Chemistry, Faculty of Science, Urmia University, Urmia (Iran, Islamic Republic of); Kant, Krishna [University of South Australia, Ian Wark Research Institute, Mawson Lakes Campus, Mawson Lakes, Adelaide, SA 5095 (Australia); Losic, Dusan, E-mail: dusan.losic@unisa.edu.a [University of South Australia, Ian Wark Research Institute, Mawson Lakes Campus, Mawson Lakes, Adelaide, SA 5095 (Australia)

2010-02-01

Transition metal hexacyanoferrate (MeHCF) have attracted extensive attention because of their outstanding properties including, electrocatalysis, molecular magnetism, biosensing and ion-exchange. This paper describes an approach for fabrication of ordered nanoarrays of Ni hexacyanoferrate (NiHCF) structures with different morphologies such as dots, rods and tubes in order to advance their properties and applications. The method is based on the conversion of Ni into NiHCF nanostructures by electrochemical oxidation in the presence of hexacyanoferrate ions, using nanoporous anodic alumina oxide (AAO) as a template. The structure and morphology of formed Ni and NiHCF nanoarrays were confirmed by scanning electron microscopy (SEM), showing agreement with the pore structures of the AAO template. The electrocatalytic activity of NiHCF nanorod array electrodes showed high catalytic properties for the detection of hydrogen peroxide and the potential to be used as a platform for direct biosensing applications. The ion-exchange ability of fabricated NiHCF nanostructures (nanorods and nanotubes) toward alkali cations such as Na{sup +} has been successfully confirmed.

Electrochemical synthesis of nickel hexacyanoferrate nanoarrays with dots, rods and nanotubes morphology using a porous alumina template

International Nuclear Information System (INIS)

Sabzi, Reza Emamali; Kant, Krishna; Losic, Dusan

2010-01-01

Transition metal hexacyanoferrate (MeHCF) have attracted extensive attention because of their outstanding properties including, electrocatalysis, molecular magnetism, biosensing and ion-exchange. This paper describes an approach for fabrication of ordered nanoarrays of Ni hexacyanoferrate (NiHCF) structures with different morphologies such as dots, rods and tubes in order to advance their properties and applications. The method is based on the conversion of Ni into NiHCF nanostructures by electrochemical oxidation in the presence of hexacyanoferrate ions, using nanoporous anodic alumina oxide (AAO) as a template. The structure and morphology of formed Ni and NiHCF nanoarrays were confirmed by scanning electron microscopy (SEM), showing agreement with the pore structures of the AAO template. The electrocatalytic activity of NiHCF nanorod array electrodes showed high catalytic properties for the detection of hydrogen peroxide and the potential to be used as a platform for direct biosensing applications. The ion-exchange ability of fabricated NiHCF nanostructures (nanorods and nanotubes) toward alkali cations such as Na + has been successfully confirmed.

Treatment of fast reactor liquid waste- electrochemical method

International Nuclear Information System (INIS)

Mahato, Swapan Kumar; Sudha, R.; Anthonysamy, S.; Muralidaran, P.

2015-01-01

During the operation of fast reactors, components get wetted by sodium. The sodium wetted primary components such as pumps and intermediate heat exchangers (IHX) in fast reactors are cleaned free of sodium followed by suitable chemical decontamination process before taking them for maintenance or for disposal. This helps in reduction of radiation dose to the operating personnel. Sodium cleaning and decontamination generates large volumes of liquid effluent. The activity in the liquid effluent during sodium cleaning/decontamination is due to 22 Na, 54 Mn, 58 Co, 60 Co, 59 Fe, 137 Cs and 134 Cs. It is required to chemically treat the effluent to reduce the activity levels prior to storage in tanks and transportation to the waste management facility for final disposal. Conventionally the ion exchange method is used for removal of radionuclides which produces large quantities of secondary waste. A method which is suitable both for removal of radionuclides present in low concentration and that avoids generation of large quantities of secondary waste is required. Hence an electrochemical method for metal ion removal is attempted in this work which produces little or no secondary waste. Electrochemical method towards removal of manganese ions was finalized earlier using reticulated vitreous carbon (RVC) from simulated decontamination solution containing a mixture of sulphuric and phosphoric acids. In continuation of the experiments for the removal of cesium ions from simulated cleaning solution which has an alkaline pH, a thin film of nickel hexacyanoferrate (NiHCF) was deposited electrochemically on the surface of RVC. Hexacyanoferrates are known for selectively binding cesium. This NiHCF coated RVC was used for electrodeposition of Cs ions. NiHCF coated and Cs deposited RVC was characterized using SEM/EDX analysis. EDX analysis confirms the presence of Cs on NiHCF coated RVC. (author)

Performance of the Fuel Conditioning Facility electronic in-cell mass balances

International Nuclear Information System (INIS)

Orechwa, Y.; Bucher, R.G.

1996-01-01

An approach to error estimation and measurement control in the analysis of the balance measurements of mass standards on the in-cell electronic mass balances of the Fuel Conditioning Facility is presented. In light of measurement data from one year of operation, the algorithms proposed are evaluated. The need to take into account the effects of facility operations on the estimates of measurement uncertainty is demonstrated. In the case of a newly installed balance, where no historical data exists, an ad hoc procedure of adding a term which takes into account the operational variability is proposed. This procedure allows a sufficiently long operation so as to collect data for the estimate of the contribution of operational effects to the uncertainty estimate. An algorithm for systematically taking into account historical data is developed and demonstrated for two balances over two calibration periods. The algorithm, both asymptotically and in the two samples cases, has the necessary desirable properties for estimating the uncertainty in the measurements of the balances

Initiation of a ring approach to infection prevention and control at non-Ebola health care facilities - Liberia, January-February 2015.

Science.gov (United States)

Nyenswah, Tolbert; Massaquoi, Moses; Gbanya, Miatta Zenabu; Fallah, Mosoka; Amegashie, Fred; Kenta, Adolphus; Johnson, Kumblytee L; Yahya, Disu; Badini, Mehboob; Soro, Lacina; Pessoa-Silva, Carmem L; Roger, Isabelle; Selvey, Linda; VanderEnde, Kristin; Murphy, Matthew; Cooley, Laura A; Olsen, Sonja J; Christie, Athalia; Vertefeuille, John; Navin, Thomas; McElroy, Peter; Park, Benjamin J; Esswein, Eric; Fagan, Ryan; Mahoney, Frank

2015-05-15

From mid-January to mid-February 2015, all confirmed Ebola virus disease (Ebola) cases that occurred in Liberia were epidemiologically linked to a single index patient from the St. Paul Bridge area of Montserrado County. Of the 22 confirmed patients in this cluster, eight (36%) sought and received care from at least one of 10 non-Ebola health care facilities (HCFs), including clinics and hospitals in Montserrado and Margibi counties, before admission to an Ebola treatment unit. After recognition that three patients in this emerging cluster had received care from a non-Ebola treatment unit, and in response to the risk for Ebola transmission in non-Ebola treatment unit health care settings, a focused infection prevention and control (IPC) rapid response effort for the immediate area was developed to target facilities at increased risk for exposure to a person with Ebola (Ring IPC). The Ring IPC approach, which provided rapid, intensive, and short-term IPC support to HCFs in areas of active Ebola transmission, was an addition to Liberia's proposed longer term national IPC strategy, which focused on providing a comprehensive package of IPC training and support to all HCFs in the country. This report describes possible health care worker exposures to the cluster's eight patients who sought care from an HCF and implementation of the Ring IPC approach. On May 9, 2015, the World Health Organization (WHO) declared the end of the Ebola outbreak in Liberia.

Flavanol-rich cocoa consumption enhances exercise-induced executive function improvements in humans.

Science.gov (United States)

Tsukamoto, Hayato; Suga, Tadashi; Ishibashi, Aya; Takenaka, Saki; Tanaka, Daichi; Hirano, Yoshitaka; Hamaoka, Takafumi; Goto, Kazushige; Ebi, Kumiko; Isaka, Tadao; Hashimoto, Takeshi

2018-02-01

Aerobic exercise is known to acutely improve cognitive functions, such as executive function (EF) and memory function (MF). Additionally, consumption of flavanol-rich cocoa has been reported to acutely improve cognitive function. The aim of this study was to determine whether high cocoa flavanol (CF; HCF) consumption would enhance exercise-induced improvement in cognitive function. To test this hypothesis, we examined the combined effects of HCF consumption and moderate-intensity exercise on EF and MF during postexercise recovery. Ten healthy young men received either an HCF (563 mg of CF) or energy-matched low CF (LCF; 38 mg of CF) beverage 70 min before exercise in a single-blind counterbalanced manner. The men then performed moderate-intensity cycling exercise at 60% of peak oxygen uptake for 30 min. The participants performed a color-word Stroop task and face-name matching task to evaluate EF and MF, respectively, during six time periods throughout the experimental session. EF significantly improved immediately after exercise compared with before exercise in both conditions. However, EF was higher after HCF consumption than after LCF consumption during all time periods because HCF consumption improved EF before exercise. In contrast, HCF consumption and moderate-intensity exercise did not improve MF throughout the experiment. The present findings demonstrated that HCF consumption before moderate-intensity exercise could enhance exercise-induced improvement in EF, but not in MF. Therefore, we suggest that the combination of HCF consumption and aerobic exercise may be beneficial for improving EF. Copyright © 2017 Elsevier Inc. All rights reserved.

Development of a grow-cell test facility for research into sustainable controlled-environment agriculture

OpenAIRE

Tsitsimpelis, Ioannis; Wolfenden, Ian; Taylor, C. James

2016-01-01

The grow-cell belongs to a relatively new category of plant factory in the horticultural industry, for which the motivation is the maximization of production and the minimization of energy consumption. This article takes a systems design approach to identify the engineering requirements of a new grow-cell facility, with the prototype based on a 12 m X 2.4 m X 2.5 m shipping container. Research contributions are made in respect to: (i) the design of a novel conveyor-irrigation system for mecha...

Environmental Assessment for decontaminating and decommissioning the General Atomics Hot Cell Facility. Final [report

International Nuclear Information System (INIS)

1995-08-01

This EA evaluates the proposed action to decontaminate and decommission GA's hot cell facility in northern San Diego, CA. This facility has been used for DOE and commercial nuclear R ampersand D for > 30 years. About 30,000 cubic feet of decontamination debris and up to 50,000 cubic feet of contaminated soil are to be removed. Low-level radioactive waste would be shipped for disposal. It was determined that the proposal does not constitute a major federal action significantly affecting the human environment according to NEPA; therefore, a finding of no significant impact is made, and an environmental impact statement is not required

Environmental Assessment for decontaminating and decommissioning the General Atomics Hot Cell Facility. Final [report

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-08-01

This EA evaluates the proposed action to decontaminate and decommission GA`s hot cell facility in northern San Diego, CA. This facility has been used for DOE and commercial nuclear R&D for > 30 years. About 30,000 cubic feet of decontamination debris and up to 50,000 cubic feet of contaminated soil are to be removed. Low-level radioactive waste would be shipped for disposal. It was determined that the proposal does not constitute a major federal action significantly affecting the human environment according to NEPA; therefore, a finding of no significant impact is made, and an environmental impact statement is not required.

Aegle marmelos Mediated Green Synthesis of Different Nanostructured Metal Hexacyanoferrates: Activity against Photodegradation of Harmful Organic Dyes

Directory of Open Access Journals (Sweden)

Vidhisha Jassal

2016-01-01

Full Text Available Prussian blue analogue potassium metal hexacyanoferrate (KMHCF nanoparticles Fe4[Fe(CN6]3 (FeHCF, K2Cu3[Fe(CN6]2 (KCuHCF, K2Ni[Fe(CN6]·3H2O (KNiHCF, and K2Co[Fe(CN6] (KCoHCF have been synthesized using plant based biosurfactant Aegle marmelos (Bael and water as a green solvent. It must be emphasized here that no harmful reagent or solvent was used throughout the study. Plant extracts are easily biodegradable and therefore do not cause any harm to the environment. Hence, the proposed method of synthesis of various KMHCF nanoparticles followed a green path. The synthesized nanoparticles were characterized by powder X-ray diffraction (PXRD, Field-Emission Scanning Electron Microscopy (FE-SEM, Transmission Electron Microscopy (TEM, and Fourier Transform Infrared Spectroscopy (FT-IR. MHCF nanoparticles were used for the photocatalytic degradation of toxic dyes like Malachite Green (MG, Eriochrome Black T (EBT, Methyl Orange (MO, and Methylene Blue (MB. Under optimized reaction conditions, maximum photocatalytic degradation was achieved in case of KCuHCF nanoparticles mediated degradation process (MG: 96.06%, EBT: 83.03%, MB: 94.72%, and MO: 63.71% followed by KNiHCF (MG: 95%, EBT: 80.32%, MB: 91.35%, and MO: 59.42%, KCoHCF (MG: 91.45%, EBT: 78.84%, MB: 89.28%, and MO: 58.20%.

The form and context of federalism: meanings for health care financing.

Science.gov (United States)

France, George

2008-08-01

This article examines the meaning of federalism for health care financing (HCF) and is based on two considerations. First, federal institutions are embedded in their national context and interact with them. The design and performance of HCF policy will be influenced by contexts, the workings of the federal institutions, and the interactions of these institutions with different elements of the context. This article unravels these influences. Second, there is no unique model of federalism, and so we have to specify the particular form to which we refer. The examination of the influence of federalism and its context on HCF policy is facilitated by using a transnational comparative approach, and this article examines four mature federations: the United States, Australia, Canada, and Germany. The relatively poor performance of the U.S. HCF system seems associated with the fact that it operates in a context markedly less benign than those of the other national HCF systems. Heterogeneity of context appears also to have contributed to important differences between the United States and the other countries in the design of HCF policies. An analysis of how federalism works in practice suggests that, while U.S. federalism may be overall less favorable to the development of well-functioning HCF policies, the inferior performance of these policies is to be principally attributed to context.

Environmental conditions in health care facilities in low- and middle-income countries: Coverage and inequalities.

Science.gov (United States)

Cronk, Ryan; Bartram, Jamie

2018-04-01

Safe environmental conditions and the availability of standard precaution items are important to prevent and treat infection in health care facilities (HCFs) and to achieve Sustainable Development Goal (SDG) targets for health and water, sanitation, and hygiene. Baseline coverage estimates for HCFs have yet to be formed for the SDGs; and there is little evidence describing inequalities in coverage. To address this, we produced the first coverage estimates of environmental conditions and standard precaution items in HCFs in low- and middle-income countries (LMICs); and explored factors associated with low coverage. Data from monitoring reports and peer-reviewed literature were systematically compiled; and information on conditions, service levels, and inequalities tabulated. We used logistic regression to identify factors associated with low coverage. Data for 21 indicators of environmental conditions and standard precaution items were compiled from 78 LMICs which were representative of 129,557 HCFs. 50% of HCFs lack piped water, 33% lack improved sanitation, 39% lack handwashing soap, 39% lack adequate infectious waste disposal, 73% lack sterilization equipment, and 59% lack reliable energy services. Using nationally representative data from six countries, 2% of HCFs provide all four of water, sanitation, hygiene, and waste management services. Statistically significant inequalities in coverage exist between HCFs by: urban-rural setting, managing authority, facility type, and sub-national administrative unit. We identified important, previously undocumented inequalities and environmental health challenges faced by HCFs in LMICs. The information and analyses provide evidence for those engaged in improving HCF conditions to develop evidence-based policies and efficient programs, enhance service delivery systems, and make better use of available resources. Copyright © 2018 The Authors. Published by Elsevier GmbH.. All rights reserved.

Shield wall evaluation of hot cell facility for advanced spent fuel conditioning process

International Nuclear Information System (INIS)

Cho, I. J.; Kuk, D. H.; Ko, J. H.; Jung, W. M.; Yoo, G. S.; Lee, E. P.; Park, S. W.

2002-01-01

The future hot cell is located in the Irradiated Material Experiment Facility (IMEF) at the Korea Atomic Energy Research Institute (KAERI). It is β-γ type hot cell that was constructed on the base floor in IMEF building for irradiated material testing. And this hot cell will be used for carrying out the Advanced spent fuel Conditioning Process (ACP). The radiation shielding capability of hot cell should be sufficient to meet the radiation dose requirements in the related regulations. Because the radioactive sources of ACP are expected to be higher than radioactive sources of IMEF design criteria, the future hot cell in current status is unsatisfactory to hot test of ACP. So the shielding analysis of the future hot cell is performed to evaluate shielding ability of concrete shield wall. The shielding analysis included (a) identification of ACP source term; (b) photon source spectrum; (c) shielding analysis by QADS and MCNP-4C; and (d) enhancement of concrete shield wall. In this research, dose rates are obtained according to ACP source, geometry and hot cell shield wall thickness. And the evaluation and reinforcement thickness of the shield wall about future hot cell are concluded

Facile modification of gelatin-based microcarriers with multiporous surface and proliferative growth factors delivery to enhance cell growth

Energy Technology Data Exchange (ETDEWEB)

Huang Sha [Department of Oral Histology and Pathology, School of Stomatology, Fourth Military Medical University, Xi' an 710032 (China); Research and Development Center for Tissue Engineering, Fourth Military Medical University, Xi' an 710032 (China); Wang Yijuan [Key Laboratory for Macromolecular Science of Shaanxi Province, Shaanxi Normal University, Xi' an 710062 (China); Deng, Tianzheng [Research and Development Center for Tissue Engineering, Fourth Military Medical University, Xi' an 710032 (China); Department of Oral and Maxillofacial Surgery, School of Stomatology, Fourth Military Medical University, Xi' an 710032 (China); Jin Fang [Department of Orthodontics, School of Stomatology, Fourth Military Medical University, Xi' an, 710032 (China); Liu Shouxin [Key Laboratory for Macromolecular Science of Shaanxi Province, Shaanxi Normal University, Xi' an 710062 (China); Zhang Yongjie [Department of Oral Histology and Pathology, School of Stomatology, Fourth Military Medical University, Xi' an 710032 (China); Research and Development Center for Tissue Engineering, Fourth Military Medical University, Xi' an 710032 (China); Feng Feng [Research and Development Center for Tissue Engineering, Fourth Military Medical University, Xi' an 710032 (China); Department of Dermatology, Tangdu Hospital, Fourth Military Medical University, Xi' an 710038 (China); Jin Yan [Department of Oral Histology and Pathology, School of Stomatology, Fourth Military Medical University, Xi' an 710032 (China); Research and Development Center for Tissue Engineering, Fourth Military Medical University, Xi' an 710032 (China)], E-mail: yanjin@fmmu.edu.cn

2008-07-28

The design of microcarriers plays an important role in the success of cell expansion. The present article provides a facile approach to modify the gelatin-based particles and investigates the feasibility of their acting as microcarriers for cell attachment and growth. Gelatin particles (150-320 {mu}m) were modified by cryogenic treatment and lyophilization to develop the surface with the features of multiporous morphology and were incorporated with proliferative growth factors (bFGF) by adsorption during the post-preparation, which enables them to serve as microcarriers for cells amplification, together with the advantages of larger cell-surface contact area and capability of promoting cell propagation. The microstructure and release assay of the modified microcarriers demonstrated that the pores on surface were uniform and bFGF was released in a controlled manner. Through in vitro fibroblast culture, these features resulted in a prominent increase in the cell attachment rate and cell growth rate relative to the conditions without modification. Although the scanning electron microscopy and optical microscopy analysis results indicated that cells attached, spread, and proliferated on all the microcarriers, cell growth clearly showed a significant correlation with the multiporous structure of microcarriers, in particular on bFGF combined ones. These results validate our previous assumption that the facile modification could improve cell growth on the gelatin-based microcarriers obviously and the novel microcarriers may be a promising candidate in tissue engineering.

Facile modification of gelatin-based microcarriers with multiporous surface and proliferative growth factors delivery to enhance cell growth

International Nuclear Information System (INIS)

Huang Sha; Wang Yijuan; Deng, Tianzheng; Jin Fang; Liu Shouxin; Zhang Yongjie; Feng Feng; Jin Yan

2008-01-01

The design of microcarriers plays an important role in the success of cell expansion. The present article provides a facile approach to modify the gelatin-based particles and investigates the feasibility of their acting as microcarriers for cell attachment and growth. Gelatin particles (150-320 μm) were modified by cryogenic treatment and lyophilization to develop the surface with the features of multiporous morphology and were incorporated with proliferative growth factors (bFGF) by adsorption during the post-preparation, which enables them to serve as microcarriers for cells amplification, together with the advantages of larger cell-surface contact area and capability of promoting cell propagation. The microstructure and release assay of the modified microcarriers demonstrated that the pores on surface were uniform and bFGF was released in a controlled manner. Through in vitro fibroblast culture, these features resulted in a prominent increase in the cell attachment rate and cell growth rate relative to the conditions without modification. Although the scanning electron microscopy and optical microscopy analysis results indicated that cells attached, spread, and proliferated on all the microcarriers, cell growth clearly showed a significant correlation with the multiporous structure of microcarriers, in particular on bFGF combined ones. These results validate our previous assumption that the facile modification could improve cell growth on the gelatin-based microcarriers obviously and the novel microcarriers may be a promising candidate in tissue engineering

Central Facilities Area Sewage Lagoon Evaluation

Energy Technology Data Exchange (ETDEWEB)

Giesbrecht, Alan [Idaho National Lab. (INL), Idaho Falls, ID (United States)

2015-03-01

The Central Facilities Area (CFA) located in Butte County, Idaho at Idaho National Laboratory (INL) has an existing wastewater system to collect and treat sanitary wastewater and non contact cooling water from the facility. The existing treatment facility consists of three cells: Cell 1 has a surface area of 1.7 acres, Cell 2 has a surface area of 10.3 acres, and Cell 3 has a surface area of 0.5 acres. If flows exceed the evaporative capacity of the cells, wastewater is discharged to a 73.5 acre land application site that utilizes a center pivot irrigation sprinkler system. The purpose of this current study is to update the analysis and conclusions of the December 2013 study. In this current study, the new seepage rate and influent flow rate data have been used to update the calculations, model, and analysis.

K1-xMn1+x/2[Fe(CN)6]·yH2O Prussian blue analogues as an anode material for lithium-ion batteries

Science.gov (United States)

Zhou, Feng-Chen; Sun, Yan-Hui; Li, Jie-Qiong; Nan, Jun-Min

2018-06-01

Hexacyanoferrate, KMn[Fe(CN)6]·yH2O (KMnHCF), a Prussian blue analogue (PBA), is synthesized by a solution precipitation method under alkaline condition at room temperature. After treated with diluted hydrochloride acid, the KMnHCF is turned into Mn3[Fe(CN)6]2·yH2O (MnHCF). Then both synthesized KMnHCF and MnHCF are applied as anode material for lithium ion batteries (LIBs). The KMnHCF anode exhibits a super electrochemical performance than MnHCF. It shows a very low discharge voltage plateau of 0.6 V, an initial capacity of 777 mAh g-1, and a reversible capacity of 434 mAh g-1 after 50 cycles at a current density of 50 mA g-1. Furthermore, it keeps 425 mAh g-1 after 100 cycles at 100 mA g-1 and 215 mAh g-1 after 200 cycles even at 500 mA g-1. It is remarkable that the coulombic efficiency can be maintained larger than 98.4% from the 5th cycle at 50 mA g-1, 99.2% at 100 mA g-1, and 96.8% even at 500 mA g-1. In addition, the original structure of the KMnHCF has no obvious change after lithiation/de-lithiation based on the ex-situ X-ray powder diffraction (XRD) and Fourier transform infrared spectrometer (FT-IR) characterization, indicating large channels and interstitial sites in the open-framework can allow rapid insertion and extraction of Li+ and constrain volume expansion during charge/discharge process.

Bejing synchrotron radiation TXRF facility and its applications on trace element study of cells

International Nuclear Information System (INIS)

Yuying, H.; Yingrong, W.; Limin, Z.; Guangcheng, L.; Wie, H.

2000-01-01

In this paper, Beijing synchrotron radiation TXRF facility and experimental method were described. The minimum detection limits of some elements were tested by using several kinds of standard reference materials. The feasibility of using TXRF in biomedical field is discussed. With this technique small intestine cells of both normal and radiated white mice were analyzed, and the elemental average contents of each single cell are also given. The results indicated that the contents of some trace elements for normal and radiated white mice are greatly different, which may be used to provide valuable reference for clinic medicine. On the other hand, the trace elements of cells of lung and cervix cancer before and after apoptosis were determined by SRTXRF and the changes of trace elements in these cells were discussed. (author)

Photovoltaic Engineering Testbed: A Facility for Space Calibration and Measurement of Solar Cells on the International Space Station

Science.gov (United States)

Landis, Geoffrey A.; Bailey, Sheila G.; Jenkins, Phillip; Sexton, J. Andrew; Scheiman, David; Christie, Robert; Charpie, James; Gerber, Scott S.; Johnson, D. Bruce

2001-01-01

The Photovoltaic Engineering Testbed ("PET") is a facility to be flown on the International Space Station to perform calibration, measurement, and qualification of solar cells in the space environment and then returning the cells to Earth for laboratory use. PET will allow rapid turnaround testing of new photovoltaic technology under AM0 conditions.

Thermal analysis of the unloading cell of the Spanish centralized interim storage facility (CISF)

International Nuclear Information System (INIS)

Perez Dominguez, J. R.; Perez Vara, R.; Huelamo Martinez, E.

2016-01-01

This article deals with the thermal analysis performed for the Untoading Cell of Spain Centralized Interim Storage Facility, CISF (ATC, in Spanish). The analyses are done using computational fluid dynamics (CFD) simulation, with the aim of obtaining the air flow required to remove the residual heat of the elements stored in the cell. Compliance with the admissible heat limits is checked with the results obtained in the various operation and accident modes. The calculation model is flexible enough to allow carrying out a number of sensitivity analyses with the different parameters involved in the process. (Author)

Facile Synthesis and High performance of a New Carbazole-Based Hole Transporting Material for Hybrid Perovskite Solar Cells

KAUST Repository

Wang, Hong

2015-06-26

Perovskite solar cells are very promising for practical applications owing to their rapidly rising power conversion efficiency and low cost of solution-based processing. 2,2’,7,7’-tetrakis-(N,N-di-p-methoxyphenylamine) 9,9’-spirobifluorene (Spiro-OMeTAD) is most widely used as hole transporting material (HTM) in perovskite solar cells. However, the tedious synthesis and high cost of Spiro-OMeTAD inhibit its commercial-scale application in the photovoltaic industry. In this article, we report a carbazole-based compound (R01) as a new HTM in efficient perovskite solar cells. R01 is synthesized via a facile route consisting of only two steps from inexpensive commercially available materials. Furthermore, R01 exhibits higher hole mobility and conductivity than the state-of-the-art Spiro-OMeTAD. Perovskite solar cells fabricated with R01 produce a power conversion efficiency of 12.03%, comparable to that obtained in devices using Spiro-OMeTAD in this study. Our findings underscore R01 as a highly promising HTM with high performance, and its facile synthesis and low cost may facilitate the large-scale applications of perovskite solar cells.

Facile Synthesis and High performance of a New Carbazole-Based Hole Transporting Material for Hybrid Perovskite Solar Cells

KAUST Repository

Wang, Hong; Sheikh, Arif D.; Feng, Quanyou; Li, Feng; Chen, Yin; Yu, Weili; Alarousu, Erkki; Ma, Chun; Haque, Mohammed; Shi, Dong; Wang, Zhong-Sheng; Mohammed, Omar F.; Bakr, Osman; Wu, Tao

2015-01-01

Perovskite solar cells are very promising for practical applications owing to their rapidly rising power conversion efficiency and low cost of solution-based processing. 2,2’,7,7’-tetrakis-(N,N-di-p-methoxyphenylamine) 9,9’-spirobifluorene (Spiro-OMeTAD) is most widely used as hole transporting material (HTM) in perovskite solar cells. However, the tedious synthesis and high cost of Spiro-OMeTAD inhibit its commercial-scale application in the photovoltaic industry. In this article, we report a carbazole-based compound (R01) as a new HTM in efficient perovskite solar cells. R01 is synthesized via a facile route consisting of only two steps from inexpensive commercially available materials. Furthermore, R01 exhibits higher hole mobility and conductivity than the state-of-the-art Spiro-OMeTAD. Perovskite solar cells fabricated with R01 produce a power conversion efficiency of 12.03%, comparable to that obtained in devices using Spiro-OMeTAD in this study. Our findings underscore R01 as a highly promising HTM with high performance, and its facile synthesis and low cost may facilitate the large-scale applications of perovskite solar cells.

The INFN-LNL single-ion horizontal microbeam facility for cell irradiation

International Nuclear Information System (INIS)

Gerardi, S.; Galeazzi, G.; Cherubini, R.

2003-01-01

Full text: Charged particle microbeams provide a unique method to control precisely the dose and its localisation within the cell. Such a kind of tool allows studying a number of important radiobiological processes in ways that cannot be achieved using conventional broad beam irradiation, which has the inherent experimental limitation imposed by the random Poisson-distributed particle hitting. We have designed and developed an apparatus for the micro-collimation in air of low-energy light ion beams, able to deliver targeted and counted particles to individual cells with an overall spatial resolution of few micrometers. The apparatus has been built up at the 7MV Van de Graaff CN accelerator, delivering protons, deuterons, helium-3 and helium-4 ion beams in an LET range from 7 to 180 keV/μm. The beam section is reduced down to 3-7 μm 2 by means of a tantalum pinhole microcollimator. A semi-automatic cell visualization and an automatic cell positioning and (after irradiation) cell revisiting system, based on an inverted phase contrast optical microscope and on X-Y micro-positioning stages with 0.1μm positioning precision, has been developed. Cell recognition is performed without using fluorescent staining and UV light. Particle detection in air is based on a silicon detector while beam profile and precise hit position measurements are accomplished by a high resolution and high sensibility cooled-CCD camera and Solid State Nuclear Track detectors, respectively. A dedicated software program, CELLView named, has been developed by using the LabView 6.0 package (National Instruments) to control all the irradiation protocol operations of sample holder movement, cell visualization, image acquisition and processing, cell data logging, cell positioning and revisiting. Facility performances and preliminary experimental results will be presented

Performance of the 2 × 4-cell superconducting linac module for the THz-FEL facility

Science.gov (United States)

Kui, Zhou; Chenglong, Lao; Dai, Wu; Xing, Luo; Jianxin, Wang; Dexin, Xiao; Lijun, Shan; Tianhui, He; Xuming, Shen; Sifen, Lin; Linde, Yang; Hanbin, Wang; Xingfan, Yang; Ming, Li; Xiangyang, Lu

2018-07-01

A high average power THz radiation facility has been developed by the China Academy of Engineering Physics. It is the first CW THz user facility based on superconducting accelerator technology in China. The superconducting linac module, which contains two 4-cell 1.3 GHz TESLA-like superconducting radio frequency cavities, is a major component of this facility. The expected electron energy gain is 6-8 MeV with a field gradient of 8-10 MV/m. The design and fabrication of the linac module is complete. This paper discusses its assembly and results from cyromodule tests and beam commissioning. At 2 K, the cryomodule works smoothly and stably. Both cavities have achieved effective field gradients of 10 MV/m. In beam loading experiments, 8 MeV, 5 mA electron beams with an energy spread less than 0.2% have been produced, which satisfies our requirements.

Selective removal of cesium from aqueous solutions with nickel (II) hexacyanoferrate (III) functionalized agricultural residue-walnut shell.

Science.gov (United States)

Ding, Dahu; Lei, Zhongfang; Yang, Yingnan; Feng, Chuanping; Zhang, Zhenya

2014-04-15

A novel nickel (II) hexacyanoferrate (III) functionalized agricultural residue-walnut shell (Ni(II)HCF(III)-WS) was developed to selectively remove cesium ion (Cs(+)) from aqueous solutions. This paper showed the first integral study on Cs(+) removal behavior and waste reduction analysis by using biomass adsorption material. The results indicated that the removal process was rapid and reached saturation within 2h. As a special characteristic of Ni(II)HCF(III)-WS, acidic condition was preferred for Cs(+) removal, which was useful for extending the application scope of the prepared biomass material in treating acidic radioactive liquid waste. The newly developed Ni(II)HCF(III)-WS could selectively remove Cs(+) though the coexisting ions (Na(+) and K(+) in this study) exhibited negative effects. In addition, approximately 99.8% (in volume) of the liquid waste was reduced by using Ni(II)HCF(III)-WS and furthermore 91.9% (in volume) of the spent biomass material (Cs-Ni(II)HCF(III)-WS) was reduced after incineration (at 500°C for 2h). Due to its relatively high distribution coefficient and significant volume reduction, Ni(II)HCF(III)-WS is expected to be a promising material for Cs(+) removal in practice. Copyright © 2014 Elsevier B.V. All rights reserved.

Waste Calcining Facility remote inspection report

International Nuclear Information System (INIS)

Patterson, M.W.; Ison, W.M.

1994-08-01

The purpose of the Waste Calcining Facility (WCF) remote inspections was to evaluate areas in the facility which are difficult to access due to high radiation fields. The areas inspected were the ventilation exhaust duct, waste hold cell, adsorber manifold cell, off-gas cell, calciner cell and calciner vessel. The WCF solidified acidic, high-level mixed waste generated during nuclear fuel reprocessing. Solidification was accomplished through high temperature oxidation and evaporation. Since its shutdown in 1981, the WCFs vessels, piping systems, pumps, off-gas blowers and process cells have remained contaminated. Access to the below-grade areas is limited due to contamination and high radiation fields. Each inspection technique was tested with a mock-up in a radiologically clean area before the equipment was taken to the WCF for the actual inspection. During the inspections, essential information was obtained regarding the cleanliness, structural integrity, in-leakage of ground water, indications of process leaks, indications of corrosion, radiation levels and the general condition of the cells and equipment. In general, the cells contain a great deal of dust and debris, as well as hand tools, piping and miscellaneous equipment. Although the building appears to be structurally sound, the paint is peeling to some degree in all of the cells. Cracking and spalling of the concrete walls is evident in every cell, although the east wall of the off-gas cell is the worst. The results of the completed inspections and lessons learned will be used to plan future activities for stabilization and deactivation of the facility. Remote clean-up of loose piping, hand tools, and miscellaneous debris can start immediately while information from the inspections is factored into the conceptual design for deactivating the facility

Development of Experimental Facilities for Advanced Spent Fuel Management Technology

Energy Technology Data Exchange (ETDEWEB)

You, G. S.; Jung, W. M.; Ku, J. H. [and others

2004-07-01

The advanced spent fuel management process(ACP), proposed to reduce the overall volume of the PWR spent fuel and improve safety and economy of the long-term storage of spent fuel, is under research and development. This technology convert spent fuels into pure metal-base uranium with removing the highly heat generating materials(Cs, Sr) efficiently and reducing of the decay heat, volume, and radioactivity from spent fuel by 1/4. In the next phase(2004{approx}2006), the demonstration of this technology will be carried out for verification of the ACP in a laboratory scale. For this demonstration, the hot cell facilities of {alpha}-{gamma} type and auxiliary facilities are required essentially for safe handling of high radioactive materials. As the hot cell facilities for demonstration of the ACP, a existing hot cell of {beta}-{gamma} type will be refurbished to minimize construction expenditures of hot cell facility. In this study, the design requirements are established, and the process detail work flow was analysed for the optimum arrangement to ensure effective process operation in hot cell. And also, the basic and detail design of hot cell facility and process, and safety analysis was performed to secure conservative safety of hot cell facility and process.

National Biomedical Tracer Facility: Project definition study

International Nuclear Information System (INIS)

Heaton, R.; Peterson, E.; Smith, P.

1995-01-01

The Los Alamos National Laboratory is an ideal institution and New Mexico is an ideal location for siting the National Biomedical Tracer Facility (NBTF). The essence of the Los Alamos proposal is the development of two complementary irradiation facilities that combined with our existing radiochemical processing hot cell facilities and waste handling and disposal facilities provide a low cost alternative to other proposals that seek to satisfy the objectives of the NBTF. We propose the construction of a 30 MeV cyclotron facility at the site of the radiochemical facilities, and the construction of a 100 MeV target station at LAMPF to satisfy the requirements and objectives of the NBTF. We do not require any modifications to our existing radiochemical processing hot cell facilities or our waste treatment and disposal facilities to accomplish the objectives of the NBTF. The total capital cost for the facility defined by the project definition study is $15.2 M. This cost estimate includes $9.9 M for the cyclotron and associated facility, $2.0 M for the 100 MeV target station at LAMPF, and $3.3 M for design

National Biomedical Tracer Facility: Project definition study

Energy Technology Data Exchange (ETDEWEB)

Heaton, R.; Peterson, E. [Los Alamos National Lab., NM (United States); Smith, P. [Smith (P.A.) Concepts and Designs (United States)

1995-05-31

The Los Alamos National Laboratory is an ideal institution and New Mexico is an ideal location for siting the National Biomedical Tracer Facility (NBTF). The essence of the Los Alamos proposal is the development of two complementary irradiation facilities that combined with our existing radiochemical processing hot cell facilities and waste handling and disposal facilities provide a low cost alternative to other proposals that seek to satisfy the objectives of the NBTF. We propose the construction of a 30 MeV cyclotron facility at the site of the radiochemical facilities, and the construction of a 100 MeV target station at LAMPF to satisfy the requirements and objectives of the NBTF. We do not require any modifications to our existing radiochemical processing hot cell facilities or our waste treatment and disposal facilities to accomplish the objectives of the NBTF. The total capital cost for the facility defined by the project definition study is $15.2 M. This cost estimate includes $9.9 M for the cyclotron and associated facility, $2.0 M for the 100 MeV target station at LAMPF, and $3.3 M for design.

Closure Report for Corrective Action Unit 116: Area 25 Test Cell C Facility, Nevada National Security Site, Nevada

Energy Technology Data Exchange (ETDEWEB)

NSTec Environmental Restoration

2011-09-29

This Closure Report (CR) presents information supporting closure of Corrective Action Unit (CAU) 116, Area 25 Test Cell C Facility. This CR complies with the requirements of the Federal Facility Agreement and Consent Order (FFACO) that was agreed to by the State of Nevada; the U.S. Department of Energy (DOE), Environmental Management; the U.S. Department of Defense; and DOE, Legacy Management (FFACO, 1996 [as amended March 2010]). CAU 116 consists of the following two Corrective Action Sites (CASs), located in Area 25 of the Nevada National Security Site: (1) CAS 25-23-20, Nuclear Furnace Piping and (2) CAS 25-41-05, Test Cell C Facility. CAS 25-41-05 consisted of Building 3210 and the attached concrete shield wall. CAS 25-23-20 consisted of the nuclear furnace piping and tanks. Closure activities began in January 2007 and were completed in August 2011. Activities were conducted according to Revision 1 of the Streamlined Approach for Environmental Restoration Plan for CAU 116 (U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office [NNSA/NSO], 2008). This CR provides documentation supporting the completed corrective actions and provides data confirming that closure objectives for CAU 116 were met. Site characterization data and process knowledge indicated that surface areas were radiologically contaminated above release limits and that regulated and/or hazardous wastes were present in the facility.

Neutron Therapy Facility

Data.gov (United States)

Federal Laboratory Consortium — The Neutron Therapy Facility provides a moderate intensity, broad energy spectrum neutron beam that can be used for short term irradiations for radiobiology (cells)...

Hyaline cartilage regeneration by combined therapy of microfracture and long-term bone morphogenetic protein-2 delivery.

Science.gov (United States)

Yang, Hee Seok; La, Wan-Geun; Bhang, Suk Ho; Kim, Hak-Jun; Im, Gun-Il; Lee, Haeshin; Park, Jung-Ho; Kim, Byung-Soo

2011-07-01

Microfracture of cartilage induces migration of bone-marrow-derived mesenchymal stem cells. However, this treatment often results in fibrocartilage regeneration. Growth factors such as bone morphogenetic protein (BMP)-2 induce the differentiation of bone-marrow-derived mesenchymal stem cells into chondrocytes, which can be used for hyaline cartilage regeneration. Here, we tested the hypothesis that long-term delivery of BMP-2 to cartilage defects subjected to microfracture results in regeneration of high-quality hyaline-like cartilage, as opposed to short-term delivery of BMP-2 or no BMP-2 delivery. Heparin-conjugated fibrin (HCF) and normal fibrin were used as carriers for the long- and short-term delivery of BMP-2, respectively. Rabbit articular cartilage defects were treated with microfracture combined with one of the following: no treatment, fibrin, short-term delivery of BMP-2, HCF, or long-term delivery of BMP-2. Eight weeks after treatment, histological analysis revealed that the long-term delivery of BMP-2 group (microfracture + HCF + BMP-2) showed the most staining with alcian blue. A biochemical assay, real-time polymerase chain reaction assay and Western blot analysis all revealed that the long-term delivery of BMP-2 group had the highest glucosaminoglycan content as well as the highest expression level of collagen type II. Taken together, the long-term delivery of BMP-2 to cartilage defects subjected to microfracture resulted in regeneration of hyaline-like cartilage, as opposed to short-term delivery or no BMP-2 delivery. Therefore, this method could be more convenient for hyaline cartilage regeneration than autologous chondrocyte implantation due to its less invasive nature and lack of cell implantation.

catalyzed oxidation of formamidine derivative by hexacyanoferrate(III

Indian Academy of Sciences (India)

triazol-3-yl) formamidine (ATF) by hexacyanoferrate(III) (HCF) was studied spectrophotometrically in aqueous alkalinemedium. Both uncatalyzed and catalyzed reactions showed first order kinetics with respect to [HCF],whereas the reaction ...

Analytical methods and laboratory facility for the Defense Waste Processing Facility

International Nuclear Information System (INIS)

Coleman, C.J.; Dewberry, R.A.; Lethco, A.J.; Denard, C.D.

1985-01-01

This paper describes the analytical methods, instruments, and laboratory that will support vitrification of defense waste. The Defense Waste Processing Facility (DWPF) is now being constructed at Savannah River Plant (SRP). Beginning in 1989, SRP high-level defense waste will be immobilized in borosilicate glass for disposal in a federal repository. The DWPF will contain an analytical laboratory for performing process control analyses. Additional analyses will be performed for process history and process diagnostics. The DWPF analytical facility will consist of a large shielded sampling cell, three shielded analytical cells, a laboratory for instrumental analysis and chemical separations, and a counting room. Special instrumentation is being designed for use in the analytical cells, including microwave drying/dissolution apparatus, and remote pipetting devices. The instrumentation laboratory will contain inductively coupled plasma, atomic absorption, Moessbauer spectrometers, a carbon analyzer, and ion chromatography equipment. Counting equipment will include intrinsic germanium detectors, scintillation counters, Phoswich alpha, beta, gamma detectors, and a low-energy photon detector

Establishment and operation of a photovoltaic cell test facility

Energy Technology Data Exchange (ETDEWEB)

Pearsall, N.M.; Forbes, I.

1999-07-01

This report describes the setting up of a test facility at the University of Northumbria. Details of the equipment specification and procurement are given, and the commissioning and initial operation of the facility, and the measurement procedures for I-V characteristics, spectral response measurements, optical scanning and test charges are outlined. The business plan for the test facility is discussed, and operating experience is reviewed in terms of publicity, services provided, and collaboration.

Power Systems Development Facility

International Nuclear Information System (INIS)

1993-06-01

The objective of the PSDF would be to provide a modular facility which would support the development of advanced, pilot-scale, coal-based power systems and hot gas clean-up components. These pilot-scale components would be designed to be large enough so that the results can be related and projected to commercial systems. The facility would use a modular approach to enhance the flexibility and capability for testing; consequently, overall capital and operating costs when compared with stand-alone facilities would be reduced by sharing resources common to different modules. The facility would identify and resolve technical barrier, as well as-provide a structure for long-term testing and performance assessment. It is also intended that the facility would evaluate the operational and performance characteristics of the advanced power systems with both bituminous and subbituminous coals. Five technology-based experimental modules are proposed for the PSDF: (1) an advanced gasifier module, (2) a fuel cell test module, (3) a PFBC module, (4) a combustion gas turbine module, and (5) a module comprised of five hot gas cleanup particulate control devices. The final module, the PCD, would capture coal-derived ash and particles from both the PFBC and advanced gasifier gas streams to provide for overall particulate emission control, as well as to protect the combustion turbine and the fuel cell

DeBeNe Test Facilities for Fast Breeder Development

International Nuclear Information System (INIS)

Storz, R.

1980-10-01

This report gives an overview and a short description of the test facilities constructed and operated within the collaboration for fast breeder development in Germany, Belgium and the Netherlands. The facilities are grouped into Sodium Loops (Large Facilities and Laboratory Loops), Special Equipment including Hot Cells and Reprocessing, Test Facilities without Sodium, Zero Power Facilities and In-pile Loops including Irradiation Facilities

Replacement of the moderator cell unit of JRR-3's cold neutron source facility

International Nuclear Information System (INIS)

Hazawa, Tomoya; Nagahori, Kazuhisa; Kusunoki, Tsuyoshi

2006-10-01

The moderator cell of the JRR-3's cold neutron source (CNS) facility, converts thermal neutrons into cold neutrons by passing through liquid cold hydrogen. The cold neutrons are used for material and life science research such as the neutron scattering. The CNS has been operated since the start of JRR-3's in 1990. The moderator cell containing liquid hydrogen is made of stainless steel. The material irradiation lifetime is limited to 7 years due to irradiation brittleness. The first replacement was done by using a spare part made in France. This replacement work of 2006 was carried out by using the domestic moderator cell unit. The following technologies were developed for the moderator cell unit production. 1) Technical development of black treatment on moderator cell surface to increase radiation heat. 2) Development of bending technology of concentric triple tubes consisting from inside tube, Outside tube and Vacuum insulation tube. 3) Development of manufacturing technique of the moderator cell with complicated shapes. According to detail planed work procedures, replacement work was carried out. As results, the working days were reduced to 80% of old ones. The radiation dose was also reduced due to reduction of working days. It was verified by measurement of neutrons characteristics that the replaced moderator cell has the same performance as that of the old moderator cell. The domestic manufacturing of the moderator cell was succeeded. As results, the replacement cost was reduced by development of domestic production technology. (author)

Influence of the environment and phototoxicity of the live cell imaging system at IMP microbeam facility

Science.gov (United States)

Liu, Wenjing; Du, Guanghua; Guo, Jinlong; Wu, Ruqun; Wei, Junzhe; Chen, Hao; Li, Yaning; Zhao, Jing; Li, Xiaoyue

2017-08-01

To investigate the spatiotemporal dynamics of DNA damage and repair after the ion irradiation, an online live cell imaging system has been established based on the microbeam facility at Institute of Modern Physics (IMP). The system could provide a sterile and physiological environment by making use of heating plate and live cell imaging solution. The phototoxicity was investigated through the evaluation of DNA repair protein XRCC1 foci formed in HT1080-RFP cells during the imaging exposure. The intensity of the foci induced by phototoxicity was much lower compared with that of the foci induced by heavy ion hits. The results showed that although spontaneous foci were formed due to RFP exposure during live cell imaging, they had little impact on the analysis of the recruitment kinetics of XRCC1 in the foci induced by the ion irradiation.

Preliminary conceptual study of engineering-scale pyroprocess demonstration facility

International Nuclear Information System (INIS)

Moon, Seong-In; Chong, Won-Myung; You, Gil-Sung; Ku, Jeong-Hoe; Kim, Ho-Dong

2013-01-01

Highlights: ► The conceptual design of a pyroprocess demonstration facility was performed. ► The design requirements for the pyroprocess hot cell and equipment were determined. ► The maintenance concept for the pyroprocess hot cell was presented. -- Abstract: The development of an effective management technology of spent fuel is important to enhance environmental friendliness, cost viability and proliferation resistance. In Korea, pyroprocess technology has been considered as a fuel cycle option to solve the spent fuel accumulation problems. PRIDE (PyRoprocess Integrated inactive DEmonstration facility) has been developed from 2007 to 2012 in Korea as a cold test facility to support integrated pyroprocessing and an equipment demonstration, which is essential to verify the pyroprocess technology. As the next stage of PRIDE, the design requirements of an engineering-scale demonstration facility are being developed, and the preliminary conceptual design of the facility is being performed for the future. In this paper, the main design requirements for the engineering-scale pyroprocess demonstration facility were studied in the throughput of 10tHM a year. For the preliminary conceptual design of the facility, the design basis of the pyroprocess hot cell was suggested, and the main equipment, main process area, operation area, maintenance area, and so on were arranged in consideration of the effective operation of the hot cells. Also, the argon system was designed to provide and maintain a proper inert environment for the pyroprocess. The preliminary conceptual design data will be used to review the validity of the engineering-scale pyroprocess demonstration facility that enhances both safety and nonproliferation

Engine Test Facility (ETF)

Data.gov (United States)

Federal Laboratory Consortium — The Air Force Arnold Engineering Development Center's Engine Test Facility (ETF) test cells are used for development and evaluation testing of propulsion systems for...

Accelerated Development of Supramolecular Corneal Stromal-Like Assemblies from Corneal Fibroblasts in the Presence of Macromolecular Crowders.

Science.gov (United States)

Kumar, Pramod; Satyam, Abhigyan; Fan, Xingliang; Rochev, Yury; Rodriguez, Brian J; Gorelov, Alexander; Joshi, Lokesh; Raghunath, Michael; Pandit, Abhay; Zeugolis, Dimitrios I

2015-07-01

Tissue engineering by self-assembly uses the cells' secretome as a regeneration template and biological factory of trophic factors. Despite the several advantages that have been witnessed in preclinical and clinical settings, the major obstacle for wide acceptance of this technology remains the tardy extracellular matrix formation. In this study, we assessed the influence of macromolecular crowding (MMC)/excluding volume effect, a biophysical phenomenon that accelerates thermodynamic activities and biological processes by several orders of magnitude, in human corneal fibroblast (HCF) culture. Our data indicate that the addition of negatively charged galactose derivative (carrageenan) in HCF culture, even at 0.5% serum, increases by 12-fold tissue-specific matrix deposition, while maintaining physiological cell morphology and protein/gene expression. Gene analysis indicates that a glucose derivative (dextran sulfate) may drive corneal fibroblasts toward a myofibroblast lineage. Collectively, these results indicate that MMC may be suitable not only for clinical translation and commercialization of tissue engineering by self-assembly therapies, but also for the development of in vitro pathophysiology models.

Prediction of the saturated hydraulic conductivity from Brooks and Corey’s water retention parameters

NARCIS (Netherlands)

Nasta, P.; Vrugt, J.A.; Romano, N.

2013-01-01

Prediction of flow through variably saturated porous media requires accurate knowledge of the soil hydraulic properties, namely the water retention function (WRF) and the hydraulic conductivity function (HCF). Unfortunately, direct measurement of the HCF is time consuming and expensive. In this

Characterization of the 309 fuel examination facility

International Nuclear Information System (INIS)

Greenhalgh, W.O.; Cornwell, B.C.

1997-01-01

This document identifies radiological, chemical and physical conditions inside the Fuel Examination Facility. It is located inside the Plutonium Recycle Test Reactor containment structure (309 Building.) The facility was a hot cell used for examination of PRTR fuel and equipment during the 1960's. Located inside the cell is a PRTR shim rod assembly, reported are radiological conditions of the sample. The conditions were assessed as part of overall 309 Building transition

CHARACTERIZING DOE HANFORD SITE WASTE ENCAPSULATION STORAGE FACILITY CELLS USING RADBALL

Energy Technology Data Exchange (ETDEWEB)

Farfan, E.; Coleman, R.

2011-03-31

RadBall{trademark} is a novel technology that can locate and quantify unknown radioactive hazards within contaminated areas, hot cells, and gloveboxes. The device consists of a colander-like outer tungsten collimator that houses a radiation-sensitive polymer semi-sphere. The collimator has a number of small holes with tungsten inserts; as a result, specific areas of the polymer are exposed to radiation becoming increasingly more opaque in proportion to the absorbed dose. The polymer semi-sphere is imaged in an optical computed tomography scanner that produces a high resolution 3D map of optical attenuation coefficients. A subsequent analysis of the optical attenuation data using a reverse ray tracing or backprojection technique provides information on the spatial distribution of gamma-ray sources in a given area forming a 3D characterization of the area of interest. RadBall{trademark} was originally designed for dry deployments and several tests, completed at Savannah River National Laboratory and Oak Ridge National Laboratory, substantiate its modeled capabilities. This study involves the investigation of the RadBall{trademark} technology during four submerged deployments in two water filled cells at the DOE Hanford Site's Waste Encapsulation Storage Facility.

Relative cost-effectiveness of an extensively hydrolyzed casein formula containing the probiotic Lactobacillus rhamnosus GG in managing infants with cow's milk allergy in Italy

Directory of Open Access Journals (Sweden)

Guest JF

2015-06-01

Full Text Available Julian F Guest,1,2 Monica Panca,1 Olga Ovcinnikova,1 Rita Nocerino3 1CATALYST Health Economics Consultants, Northwood, Middlesex, UK; 2Faculty of Life Sciences and Medicine, King's College, London, UK; 3Department of Translational Medical Science, Pediatric Section, University of Naples 'Federico II', Naples, Italy Objective: To estimate the cost-effectiveness of using an extensively hydrolyzed casein formula (eHCF containing the probiotic Lactobacillus rhamnosus GG, (eHCF + LGG; Nutramigen LGG as first-line management for cow's milk allergy (CMA compared with eHCF alone, soy-based formulae (SBF, hydrolyzed rice formulae (HRF, and amino acid formulae (AAF in Italy, from the perspective of the Italian National Health Service (INHS and parents. Methods: Decision modeling was used to estimate the probability of infants developing tolerance to cow's milk by 18 months, based on an observational study dataset. The model also estimated the cost (at 2012/2013 prices of health care resource use funded by the INHS and formulae paid for by parents over 18 months after starting a formula, as well as the relative cost-effectiveness of each of the formulae. Results: The probability of developing tolerance to cow's milk by 18 months was higher among infants with either IgE-mediated or non-IgE-mediated allergy who were fed eHCF + LGG compared to those fed one of the other formulae. The total health care cost of initially feeding infants with eHCF + LGG was less than that of feeding infants with one of the other formulae. Hence, eHCF + LGG affords the greatest value for money to both the INHS and parents of infants with either IgE-mediated or non-IgE-mediated CMA. Conclusion: Using eHCF + LGG instead of eHCF, SBF, HRF, or an AAF for first-line management of newly diagnosed infants with CMA in Italy affords a cost-effective use of publicly funded resources, and is cost-effective from the parents' perspective, since it improves outcome for less cost. A randomized

Overview of the IFMIF test facility design in IFMIF/EVEDA phase

International Nuclear Information System (INIS)

Tian, Kuo; Abou-Sena, Ali; Arbeiter, Frederik; García, Ángela; Gouat, Philippe; Heidinger, Roland; Heinzel, Volker; Ibarra, Ángel; Leysen, Willem; Mas, Avelino; Mittwollen, Martin; Möslang, Anton; Theile, Jürgen; Yamamoto, Michiyoshi; Yokomine, Takehiko

2015-01-01

Highlights: • This paper summarizes the current design status of IFMIF EVEDA test facility. • The principle functions of the test facility and key components are described. • The brief specifications of the systems and key components are addressed. - Abstract: The test facility (TF) is one of the three major facilities of the International Fusion Material Irradiation Facility (IFMIF). Engineering designs of TF main systems and key components have been initiated and developed in the IFMIF EVEDA (Engineering Validation and Engineering Design Activities) phase since 2007. The related work covers the designs of a test cell which is the meeting point of the TF and accelerator facility and lithium facility, a series of test modules for experiments under different irradiation conditions, an access cell to accommodate remote handling systems, four test module handling cells for test module processing and assembling, and test facility ancillary systems for engineering support on energy, media, and control infrastructure. This paper summarizes the principle functions, brief specifications, and the current design status of the above mentioned IFMIF TF systems and key components.

Design of a Facility for Studying Shock-Cell Noise on Single and Coaxial Jets

Directory of Open Access Journals (Sweden)

Daniel Guariglia

2018-03-01

Full Text Available Shock-cell noise occurs in aero-engines when the nozzle exhaust is supersonic and shock-cells are present in the jet. In commercial turbofan engines, at cruise, the secondary flow is often supersonic underexpanded, with the formation of annular shock-cells in the jet and consequent onset of shock-cell noise. This paper aims at describing the design process of the new facility FAST (Free jet AeroacouSTic laboratory at the von Karman Institute, aimed at the investigation of the shock-cell noise phenomenon on a dual stream jet. The rig consists of a coaxial open jet, with supersonic capability for both the primary and secondary flow. A coaxial silencer was designed to suppress the spurious noise coming from the feeding lines. Computational fluid dynamics (CFD simulations of the coaxial jet and acoustic simulations of the silencer have been carried out to support the design choices. Finally, the rig has been validated by performing experimental measurements on a supersonic single stream jet and comparing the results with the literature. Fine-scale PIV (Particle Image Velocimetry coupled with a microphone array in the far field have been used in this scope. Preliminary results of the dual stream jet are also shown.

Selective removal of cesium from aqueous solutions with nickel (II) hexacyanoferrate (III) functionalized agricultural residue–walnut shell

International Nuclear Information System (INIS)

Ding, Dahu; Lei, Zhongfang; Yang, Yingnan; Feng, Chuanping; Zhang, Zhenya

2014-01-01

Highlights: • Novel biosorbent for cesium removal was derived from agricultural residue. • It could remove cesium effectively from aqueous solution. • Large size of granules makes it easy to be separated from solutions. • The volume of used biosorbent could be significantly reduced after incineration. • Incinerated biosorbent has a low volume and a low cost final disposal. - Abstract: A novel nickel (II) hexacyanoferrate (III) functionalized agricultural residue-walnut shell (Ni II HCF III -WS) was developed to selectively remove cesium ion (Cs + ) from aqueous solutions. This paper showed the first integral study on Cs + removal behavior and waste reduction analysis by using biomass adsorption material. The results indicated that the removal process was rapid and reached saturation within 2 h. As a special characteristic of Ni II HCF III -WS, acidic condition was preferred for Cs + removal, which was useful for extending the application scope of the prepared biomass material in treating acidic radioactive liquid waste. The newly developed Ni II HCF III -WS could selectively remove Cs + though the coexisting ions (Na + and K + in this study) exhibited negative effects. In addition, approximately 99.8% (in volume) of the liquid waste was reduced by using Ni II HCF III -WS and furthermore 91.9% (in volume) of the spent biomass material (Cs-Ni II HCF III -WS) was reduced after incineration (at 500 °C for 2 h). Due to its relatively high distribution coefficient and significant volume reduction, Ni II HCF III -WS is expected to be a promising material for Cs + removal in practice

Mössbauer spectroscopic study of cobalt hexacyanoferrate nanoparticles: Effect of hydrogenation

Science.gov (United States)

Kumar, Asheesh; Kanagare, A. B.; Meena, Sher Singh; Banerjee, S.; Kumar, P.; Sudarsan, V.

2018-04-01

This paper reports Mössbauer study of cobalt hexacyanoferrate (CoHCF) before and after hydrogenation. The CoHCF was synthesised by chemical precipitation method. The sample was characterized by using various techniques (XRD, TG, EDX and FTIR). The CoHCF paricles show fcc structure. The hydrogen storage property was measured at different temperature. The COHCF shows maximum 0.93 wt% hydrogen storage capacity at 223K. 57Fe Mössbauer spectroscopic study shows the effect of hydrogenation on the electronic structure in terms of electronic charge distribution and volume expansion. Isomer shift and quadrupole splitting values were found to be increased after hydrogenation.

Feasibility study of medical isotope production at Sandia National Laboratories

International Nuclear Information System (INIS)

Massey, C.D.; Miller, D.L.; Carson, S.D.

1995-12-01

In late 1994, Sandia National Laboratories in Albuquerque, New Mexico, (SNL/NM), was instructed by the Department of Energy (DOE) Isotope Production and Distribution Program (IPDP) to examine the feasibility of producing medically useful radioisotopes using the Annular Core Research Reactor (ACRR) and the Hot Cell Facility (HCF). Los Alamos National Laboratory (LANL) would be expected to supply the targets to be irradiated in the ACRR. The intent of DOE would be to provide a capability to satisfy the North American health care system demand for 99 Mo, the parent of 99m Tc, in the event of an interruption in the current Canadian supply. 99m Tc is used in 70 to 80% of all nuclear medicine procedures in the US. The goal of the SNL/NM study effort is to determine the physical plant capability, infrastructure, and staffing necessary to meet the North American need for 99 Mo and to identify and examine all issues with potential for environmental impact

One-Step Facile Synthesis of a Simple Hole Transport Material for Efficient Perovskite Solar Cells

KAUST Repository

Chen, Hu

2016-04-04

A hole transporting material was designed for use in perovskite solar cells, with a facile one-step synthesis from inexpensive, com-mercially available reagents. The molecule comprises a central fluorinated phenyl core with pendant aryl amines, namely, 3,6-difluoro-N1,N1,N2,N2,N4,N4,N5,N5-octakis(4-methoxyphenyl)benzene-1,2,4,5-tetraamine (DFTAB). A power conversion efficiency of up to 10.4% was achieved in a mesoporous perovskite device architecture. The merits of a simple and potentially low cost syn-thetic route as well as promising performance in perovskite devices, encourages further development of this materials class as new low-cost hole transporting materials for the scale up of perovskite solar cells.

One-Step Facile Synthesis of a Simple Hole Transport Material for Efficient Perovskite Solar Cells

KAUST Repository

Chen, Hu; Bryant, Daniel; Troughton, Joel; Kirkus, Mindaugas; Neophytou, Marios; Miao, Xiaohe; Durrant, James R.; McCulloch, Iain

2016-01-01

A hole transporting material was designed for use in perovskite solar cells, with a facile one-step synthesis from inexpensive, com-mercially available reagents. The molecule comprises a central fluorinated phenyl core with pendant aryl amines, namely, 3,6-difluoro-N1,N1,N2,N2,N4,N4,N5,N5-octakis(4-methoxyphenyl)benzene-1,2,4,5-tetraamine (DFTAB). A power conversion efficiency of up to 10.4% was achieved in a mesoporous perovskite device architecture. The merits of a simple and potentially low cost syn-thetic route as well as promising performance in perovskite devices, encourages further development of this materials class as new low-cost hole transporting materials for the scale up of perovskite solar cells.

A Contribution to Nyquist-Rate ADC Modeling - Detailed Algorithm Description

Directory of Open Access Journals (Sweden)

J. Zidek

2012-04-01

Full Text Available In this article, the innovative ADC modeling algorithm is described. It is well suitable for nyquist-rate ADC error back annotation. This algorithm is the next step of building a support tool for IC design engineers. The inspiration for us was the work [2]. Here, the ADC behavior is divided into HCF (High Code Frequency and LCF (Low Code Frequency separated independent parts. This paper is based on the same concept but the model coefficients are estimated in a different way only from INL data. The HCF order recognition part was newly added as well. Thanks to that the HCF coefficients number is lower in comparison with the original Grimaldi’s work (especially for converters with low ratio between HCF and “random” part of INL. Modeling results are demonstrated on a real data set measured by ASICentrum on chargeredistribution type SAR ADC chip. Results are showed not only by coefficient values but also by the Model Coverage metrics. Model limitations are also discussed.

Impact of Salt Waste Processing Facility Streams on the Nitric-Glycolic Flowsheet in the Chemical Processing Cell

Energy Technology Data Exchange (ETDEWEB)

Martino, C. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

2017-08-08

An evaluation of the previous Chemical Processing Cell (CPC) testing was performed to determine whether the planned concurrent operation, or “coupled” operations, of the Defense Waste Processing Facility (DWPF) with the Salt Waste Processing Facility (SWPF) has been adequately covered. Tests with the nitricglycolic acid flowsheet, which were both coupled and uncoupled with salt waste streams, included several tests that required extended boiling times. This report provides the evaluation of previous testing and the testing recommendation requested by Savannah River Remediation. The focus of the evaluation was impact on flammability in CPC vessels (i.e., hydrogen generation rate, SWPF solvent components, antifoam degradation products) and processing impacts (i.e., acid window, melter feed target, rheological properties, antifoam requirements, and chemical composition).

A novel facility for 3D micro-irradiation of living cells in a controlled environment by MeV ions.

Science.gov (United States)

Mäckel, V; Meissl, W; Ikeda, T; Clever, M; Meissl, E; Kobayashi, T; Kojima, T M; Imamoto, N; Ogiwara, K; Yamazaki, Y

2014-01-01

We present a novel facility for micro-irradiation of living targets with ions from a 1.7 MV tandem accelerator. We show results using 1 MeV protons and 2 MeV He(2+). In contrast to common micro-irradiation facilities, which use electromagnetic or electrostatic focusing and specially designed vacuum windows, we employ a tapered glass capillary with a thin end window, made from polystyrene with a thickness of 1-2 μm, for ion focusing and extraction. The capillary is connected to a beamline tilted vertically by 45°, which allows for easy immersion of the extracted ions into liquid environment within a standard cell culture dish. An inverted microscope is used for simultaneously observing the samples as well as the capillary tip, while a stage-top incubator provides an appropriate environment for the samples. Furthermore, our setup allows to target volumes in cells within a μm(3) resolution, while monitoring the target in real time during and after irradiation.

Predominant modifier of extreme liver cancer susceptibility in C57BR/cdJ female mice localized to 6 Mb on chromosome 17

Science.gov (United States)

Peychal, Stephanie E.-M.; Bilger, Andrea; Pitot, Henry C.; Drinkwater, Norman R.

2009-01-01

Sex hormones influence the susceptibility of inbred mice to liver cancer. C57BR/cdJ (BR) females are extremely susceptible to spontaneous and chemically induced liver tumors, in part due to a lack of protection against hepatocarcinogenesis normally offered by ovarian hormones. BR males are also moderately susceptible, and the susceptibility of both sexes of BR mice to liver tumors induced with N,N-diethylnitrosamine relative to the resistant C57BL/6J (B6) strain is caused by two loci designated Hcf1 and Hcf2 (hepatocarcinogenesis in females) located on chromosomes 17 and 1, respectively. The Hcf1 locus on chromosome 17 is the predominant modifier of liver cancer in BR mice. To validate the existence of this locus and investigate its potential interaction with Hcf2, congenic mice for each region were generated. Homozygosity for the B6.BR(D17Mit164-D17Mit2) region resulted in a 4-fold increase in liver tumor multiplicity in females and a 4.5-fold increase in males compared with B6 controls. A series of 16 recombinants covering the entire congenic region was developed to further narrow the area containing Hcf1. Susceptible heterozygous recombinants demonstrated a 3- to 7-fold effect in females and a 1.5- to 2-fold effect in males compared with B6 siblings. The effect in susceptible lines completely recapitulated the susceptibility of heterozygous full-length chromosome 17 congenics and furthermore narrowed the location of the Hcf1 locus to a single region of the chromosome from 30.05 to 35.83 Mb. PMID:19255062

Family food purchases of high- and low-calorie foods in full-service supermarkets and other food retailers by Black women in an urban US setting.

Science.gov (United States)

Chrisinger, Benjamin W; DiSantis, Katherine Isselmann; Hillier, Amy E; Kumanyika, Shiriki K

2018-06-01

Public health interventions to increase supermarket access assume that shopping in supermarkets is associated with healthier food purchases compared to other store types. To test this assumption, we compared purchasing patterns by store-type for certain higher-calorie, less healthy foods (HCF) and lower-calorie, healthier foods (LCF) in a sample of 35 black women household shoppers in Philadelphia, PA. Data analyzed were from 450 food shopping receipts collected by these shoppers over four-week periods in 2012. We compared the likelihood of purchasing the HCF (sugar-sweetened beverages, sweet/salty snacks, and grain-based snacks) and LCF (low-fat dairy, fruits, and vegetables) at full-service supermarkets and six other types of food retailers, using generalized estimating equations. Thirty-seven percent of participants had household incomes at or below the poverty line, and 54% had a BMI >30. Participants shopped primarily at full-service supermarkets (55%) or discount/limited assortment supermarkets (22%), making an average of 11 shopping trips over a 4-week period and spending mean (SD) of $350 ($222). Of full-service supermarket receipts, 64% included at least one HCF item and 58% at least one LCF. Most trips including HCF (58%) and LCF (60%) expenditures were to full-service or discount/limited assortment supermarkets rather than smaller stores. Spending a greater percent of total dollars in full-service supermarkets was associated with spending more on HCF (p = 0.03) but not LCF items (p = 0.26). These findings in black women suggest a need for more attention to supermarket interventions that change retailing practices and/or consumer shopping behaviors related to foods in the HCF categories examined.

Selective removal of cesium from aqueous solutions with nickel (II) hexacyanoferrate (III) functionalized agricultural residue–walnut shell

Energy Technology Data Exchange (ETDEWEB)

Ding, Dahu, E-mail: dingdahu@gmail.com [Graduate School of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8572 (Japan); Lei, Zhongfang; Yang, Yingnan [Graduate School of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8572 (Japan); Feng, Chuanping [School of Water Resources and Environment, China University of Geosciences (Beijing), Key Laboratory of Groundwater Circulation and Evolution, Ministry of Education, Beijing 100083 (China); Zhang, Zhenya, E-mail: zhang.zhenya.fu@u.tsukuba.ac.jp [Graduate School of Life and Environmental Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8572 (Japan)

2014-04-01

Highlights: • Novel biosorbent for cesium removal was derived from agricultural residue. • It could remove cesium effectively from aqueous solution. • Large size of granules makes it easy to be separated from solutions. • The volume of used biosorbent could be significantly reduced after incineration. • Incinerated biosorbent has a low volume and a low cost final disposal. - Abstract: A novel nickel (II) hexacyanoferrate (III) functionalized agricultural residue-walnut shell (Ni{sup II}HCF{sup III}-WS) was developed to selectively remove cesium ion (Cs{sup +}) from aqueous solutions. This paper showed the first integral study on Cs{sup +} removal behavior and waste reduction analysis by using biomass adsorption material. The results indicated that the removal process was rapid and reached saturation within 2 h. As a special characteristic of Ni{sup II}HCF{sup III}-WS, acidic condition was preferred for Cs{sup +} removal, which was useful for extending the application scope of the prepared biomass material in treating acidic radioactive liquid waste. The newly developed Ni{sup II}HCF{sup III}-WS could selectively remove Cs{sup +} though the coexisting ions (Na{sup +} and K{sup +} in this study) exhibited negative effects. In addition, approximately 99.8% (in volume) of the liquid waste was reduced by using Ni{sup II}HCF{sup III}-WS and furthermore 91.9% (in volume) of the spent biomass material (Cs-Ni{sup II}HCF{sup III}-WS) was reduced after incineration (at 500 °C for 2 h). Due to its relatively high distribution coefficient and significant volume reduction, Ni{sup II}HCF{sup III}-WS is expected to be a promising material for Cs{sup +} removal in practice.

Hot Fuel Examination Facility (HFEF)

Data.gov (United States)

Federal Laboratory Consortium — The Hot Fuel Examination Facility (HFEF) is one of the largest hot cells dedicated to radioactive materials research at Idaho National Laboratory (INL). The nation's...

The development of a mobile hot cell facility for the conditioning of spent high activity radioactive sources

International Nuclear Information System (INIS)

Liebenberg, G.R.; Al-Mughrabi, M.

2010-01-01

The International Atomic Energy Agency (IAEA) Waste Technology Section with additional support from the U.S. National Nuclear Security Administration (NNSA) through the IAEA Nuclear Security Fund has funded the design, fabrication, evaluation, and testing of a portable hot cell intended to address the problem of disused Spent High Activity Radioactive Sources (SHARS) in obsolete irradiation devices such as teletherapy heads and dry irradiators. The project is initially targeting the African continent but expected soon to expand to Latin America and Asia. This hot cell allows source removal, characterization, consolidation, repackaging in modern storage shields, and secure storage of high risk SHARS at national radioactive waste storage facilities. (authors)

Interim Storage Facility decommissioning. Final report

International Nuclear Information System (INIS)

Johnson, R.P.; Speed, D.L.

1985-01-01

Decontamination and decommissioning of the Interim Storage Facility were completed. Activities included performing a detailed radiation survey of the facility, removing surface and imbedded contamination, excavating and removing the fuel storage cells, restoring the site to natural conditions, and shipping waste to Hanford, Washington, for burial. The project was accomplished on schedule and 30% under budget with no measurable exposure to decommissioning personnel

Remote maintenance system for nuclear facilities

International Nuclear Information System (INIS)

Maeda, Masafumi

1993-01-01

In the facilities related to atomic energy, from the viewpoint of the reduction of radiation exposure of workers and the heightening of the rate of operation of the facilities, the development of remote maintenance system is regarded as important. Meidensha Electric Manufacturing Co., Ltd. developed the bilateral control type manipulator, BILARM-83, in 1979, and has developed high performance manipulator systems. As the design of the plant that realizes the remote operation maintenance of process machinery and equipment during plant operation, the remote maintenance system by canyon cell techniques, which was adopted in Savannah River plant, USA, and has been operated for nearly 50 years, has been known. The concept of the full remote maintenance system by large scale cell techniques was shown and has been developed by Power Reactor and Nuclear Fuel Development Corp. In order to realize the remote maintenance of such large scale cells, Meidensha is developing the both arm type bilateral servo manipulator, the single arm type power manipulator, the transport system for moving them, the power and signal system and so on. Those systems were adopted for the glass solidification facilities. (K.I.)

Development of demonstration facility design technology for advanced nuclear fuel cycle process

International Nuclear Information System (INIS)

Cho, Il Je; You, G. S.; Choung, W. M.; Lee, E. P.; Hong, D. H.; Lee, W. K.; Ku, J. H.; Moon, S. I.; Kwon, K. C.; Lee, K. I. and other

2012-04-01

PRIDE Facility, pyroprocess mock-up facility, is the first facility that is operated in inert atmosphere in the country. By using the facility, the functional requirements and validity of pyroprocess technology and facility related to the advanced fuel cycle can be verified with a low cost. Then, PRIDE will contribute to evaluate the technology viability, proliferation resistance and possibility of commercialization of the pyroprocess technology. It is essential to develop design technologies for the advanced nuclear fuel cycle demonstration facilities and complete the detailed design of PRIDE facility with capabilities of the stringent inert atmosphere control, fully remote operation which are necessary to develop the high-temperature molten salts technology. For these, it is necessary to design the essential equipment of large scale inert cell structure and the control system to maintain the inert atmosphere, and evaluate the safety. To construct the hot cell system which is appropriate for pyroprocess, some design technologies should be developed, which include safety evaluation for effective operation and maintenance, radiation safety analysis for hot cell, structural analysis, environmental evaluation, HVAC systems and electric equipment

Argonne to open new facility for advanced vehicle testing

CERN Multimedia

2002-01-01

Argonne National Laboratory will open it's Advanced Powertrain Research Facility on Friday, Nov. 15. The facility is North America's only public testing facility for engines, fuel cells, electric drives and energy storage. State-of-the-art performance and emissions measurement equipment is available to support model development and technology validation (1 page).

Outline of NUCEF facility

International Nuclear Information System (INIS)

Takeshita, Isao

1996-01-01

NUCEF is a multipurpose research facility in the field of safety and advanced technology of nuclear fuel cycle back-end. Various experiment facilities and its supporting installations, in which nuclear fuel materials, radio isotopes and TRU elements can be handled, are arranged in more than one hundred rooms of two experiment buildings. Its construction was completed in middle of 1994 and hot experiments have been started since then. NUCEF is located on the site (30,000 m 2 ) of southeastern part in the Tokai Research Establishment of JAERI facing to the Pacific Ocean. The base of Experiment Buildings A and B was directly founded on the rock existing at 10-15 m below ground level taking the aseismatic design into consideration. Each building is almost same sized and composed of one basement and three floors of which area is 17,500 m 2 in total. In the basement, there are exhaust facilities of ventilation system, treatment system of solution fuel and radioactive waste solution and storage tanks of them. Major experiment facilities are located on the first or the second floors in each building. An air-inlet facility of ventilation system for each building is equipped on the third floor. Most of experiment facilities for criticality safety research including two critical facilities: Static Experiment Critical Facility (STACY) and Transient Experiment Critical Facility (TRACY) are installed in Experiment Building A. Experiment equipments for research on advanced fuel reprocessing process and on TRU waste management, which are named BECKY (Back End Fuel Cycle Key Elements Research Facility), are installed in laboratories and a-g cells in Experiment Building B. (J.P.N.)

Boron isotope sensitivity to seawater pH change in a species of Neogoniolithon coralline red alga

Science.gov (United States)

Donald, Hannah K.; Ries, Justin B.; Stewart, Joseph A.; Fowell, Sara E.; Foster, Gavin L.

2017-11-01

The increase in atmospheric carbon dioxide (CO2) observed since the industrial revolution has reduced surface ocean pH by ∼0.1 pH units, with further change in the oceanic system predicted in the coming decades. Calcareous organisms can be negatively affected by extreme changes in seawater pH (pHsw) such as this due to the associated changes in the oceanic carbonate system. The boron isotopic composition (δ11B) of biogenic carbonates has been previously used to monitor pH at the calcification site (pHcf) in scleractinian corals, providing mechanistic insights into coral biomineralisation and the impact of variable pHsw on this process. Motivated by these investigations, this study examines the δ11B of the high-Mg calcite skeleton of the coralline red alga Neogoniolithon sp. to constrain pHcf, and investigates how this taxon's pHcf is impacted by ocean acidification. δ11B was measured in multiple algal replicates (n = 4-5) cultured at four different pCO2 scenarios - averaging (±1σ) 409 (±6), 606 (±7), 903 (±12) and 2856 (±54) μatm, corresponding to average pHsw (±1σ) of 8.19 (±0.03), 8.05 (±0.06), 7.91 (±0.03) and 7.49 (±0.02) respectively. Results show that skeletal δ11B is elevated relative to the δ11B of seawater borate at all pHsw treatments by up to 18‰. Although substantial variability in δ11B exists between replicate samples cultured at a given pHsw (smallest range = 2.32‰ at pHsw 8.19, largest range = 6.08‰ at pHsw 7.91), strong correlations are identified between δ11B and pHsw (R2 = 0.72, p < 0.0001, n = 16) and between δ11B and B/Ca (R2 = 0.72, p < 0.0001, n = 16). Assuming that skeletal δ11B reflects pHcf as previously observed for scleractinian corals, the average pHcf across all experiments was 1.20 pH units (0.79 to 1.56) higher than pHsw, with the magnitude of this offset varying parabolically with decreasing pHsw, with a maximum difference between pHsw and pHcf at a pHsw of 7.91. Observed relationships between pHsw and

Sanford Underground Research Facility - The United State's Deep Underground Research Facility

Science.gov (United States)

Vardiman, D.

2012-12-01

The 2.5 km deep Sanford Underground Research Facility (SURF) is managed by the South Dakota Science and Technology Authority (SDSTA) at the former Homestake Mine site in Lead, South Dakota. The US Department of Energy currently supports the development of the facility using a phased approach for underground deployment of experiments as they obtain an advanced design stage. The geology of the Sanford Laboratory site has been studied during the 125 years of operations at the Homestake Mine and more recently as part of the preliminary geotechnical site investigations for the NSF's Deep Underground Science and Engineering Laboratory project. The overall geology at DUSEL is a well-defined stratigraphic sequence of schist and phyllites. The three major Proterozoic units encountered in the underground consist of interbedded schist, metasediments, and amphibolite schist which are crosscut by Tertiary rhyolite dikes. Preliminary geotechnical site investigations included drift mapping, borehole drilling, borehole televiewing, in-situ stress analysis, laboratory analysis of core, mapping and laser scanning of new excavations, modeling and analysis of all geotechnical information. The investigation was focused upon the determination if the proposed site rock mass could support the world's largest (66 meter diameter) deep underground excavation. While the DUSEL project has subsequently been significantly modified, these data are still available to provide a baseline of the ground conditions which may be judiciously extrapolated throughout the entire Proterozoic rock assemblage for future excavations. Recommendations for facility instrumentation and monitoring were included in the preliminary design of the DUSEL project design and include; single and multiple point extensometers, tape extensometers and convergence measurements (pins), load cells and pressure cells, smart cables, inclinometers/Tiltmeters, Piezometers, thermistors, seismographs and accelerometers, scanners (laser

Remote operation and maintenance demonstration facility at ORNL

International Nuclear Information System (INIS)

Harvey, H.W.; Floyd, S.D.; Kuban, D.P.; Singletary, B.H.; Stradley, J.G.

1978-01-01

The Remote Operation and Maintenance Facility is a versatile facility arranged to mock up various hot cell configurations. Modular units of simulated shielding and viewing windows were built to provide flexibility in arrangement. The facility is fully equipped with hoists, manipulators, television, and other basic equipment and services necessary to provide capability for both remote operation and maintenance of several selected functional process equipment groups

Transient response and radiation dose estimates for breaches to a spent fuel processing facility

Energy Technology Data Exchange (ETDEWEB)

Solbrig, Charles W., E-mail: soltechco@aol.com; Pope, Chad; Andrus, Jason

2014-08-15

Highlights: • We model doses received from a nuclear fuel facility from boundary leaks due to an earthquake. • The supplemental exhaust system (SES) starts after breach causing air to be sucked into the cell. • Exposed metal fuel burns increasing pressure and release of radioactive contamination. • Facility releases are small and much less than the limits showing costly refits are unnecessary. • The method presented can be used in other nuclear fuel processing facilities. - Abstract: This paper describes the analysis of the design basis accident for Idaho National Laboratory Fuel Conditioning Facility (FCF). The facility is used to process spent metallic nuclear fuel. This analysis involves a model of the transient behavior of the FCF inert atmosphere hot cell following an earthquake initiated breach of pipes passing through the cell boundary. Such breaches allow the introduction of air and subsequent burning of pyrophoric metals. The model predicts the pressure, temperature, volumetric releases, cell heat transfer, metal fuel combustion, heat generation rates, radiological releases and other quantities. The results show that releases from the cell are minimal and satisfactory for safety. This analysis method should be useful in other facilities that have potential for damage from an earthquake and could eliminate the need to back fit facilities with earthquake proof boundaries or lessen the cost of new facilities.

Transient response and radiation dose estimates for breaches to a spent fuel processing facility

International Nuclear Information System (INIS)

Solbrig, Charles W.; Pope, Chad; Andrus, Jason

2014-01-01

Highlights: • We model doses received from a nuclear fuel facility from boundary leaks due to an earthquake. • The supplemental exhaust system (SES) starts after breach causing air to be sucked into the cell. • Exposed metal fuel burns increasing pressure and release of radioactive contamination. • Facility releases are small and much less than the limits showing costly refits are unnecessary. • The method presented can be used in other nuclear fuel processing facilities. - Abstract: This paper describes the analysis of the design basis accident for Idaho National Laboratory Fuel Conditioning Facility (FCF). The facility is used to process spent metallic nuclear fuel. This analysis involves a model of the transient behavior of the FCF inert atmosphere hot cell following an earthquake initiated breach of pipes passing through the cell boundary. Such breaches allow the introduction of air and subsequent burning of pyrophoric metals. The model predicts the pressure, temperature, volumetric releases, cell heat transfer, metal fuel combustion, heat generation rates, radiological releases and other quantities. The results show that releases from the cell are minimal and satisfactory for safety. This analysis method should be useful in other facilities that have potential for damage from an earthquake and could eliminate the need to back fit facilities with earthquake proof boundaries or lessen the cost of new facilities

Family food purchases of high- and low-calorie foods in full-service supermarkets and other food retailers by Black women in an urban US setting

Directory of Open Access Journals (Sweden)

Benjamin W. Chrisinger

2018-06-01

Full Text Available Public health interventions to increase supermarket access assume that shopping in supermarkets is associated with healthier food purchases compared to other store types. To test this assumption, we compared purchasing patterns by store-type for certain higher-calorie, less healthy foods (HCF and lower-calorie, healthier foods (LCF in a sample of 35 black women household shoppers in Philadelphia, PA. Data analyzed were from 450 food shopping receipts collected by these shoppers over four-week periods in 2012. We compared the likelihood of purchasing the HCF (sugar-sweetened beverages, sweet/salty snacks, and grain-based snacks and LCF (low-fat dairy, fruits, and vegetables at full-service supermarkets and six other types of food retailers, using generalized estimating equations. Thirty-seven percent of participants had household incomes at or below the poverty line, and 54% had a BMI >30. Participants shopped primarily at full-service supermarkets (55% or discount/limited assortment supermarkets (22%, making an average of 11 shopping trips over a 4-week period and spending mean (SD of $350 ($222. Of full-service supermarket receipts, 64% included at least one HCF item and 58% at least one LCF. Most trips including HCF (58% and LCF (60% expenditures were to full-service or discount/limited assortment supermarkets rather than smaller stores. Spending a greater percent of total dollars in full-service supermarkets was associated with spending more on HCF (p = 0.03 but not LCF items (p = 0.26. These findings in black women suggest a need for more attention to supermarket interventions that change retailing practices and/or consumer shopping behaviors related to foods in the HCF categories examined. Keywords: Obesity, Store choice, Food choice, Food shopping, Supermarkets, African Americans

Cyclic deformation and fatigue behaviors of Hadfield manganese steel

Energy Technology Data Exchange (ETDEWEB)

Kang, J. [State Key Laboratory of Metastable Materials Science and Technology, Yanshan University, Qinhuangdao 066004 (China); Zhang, F.C., E-mail: zfc@ysu.edu.cn [State Key Laboratory of Metastable Materials Science and Technology, Yanshan University, Qinhuangdao 066004 (China); Long, X.Y. [State Key Laboratory of Metastable Materials Science and Technology, Yanshan University, Qinhuangdao 066004 (China); Lv, B. [School of Environmental and Chemical Engineering, Yanshan University, Qinhuangdao 066004 (China)

2014-01-03

The cyclic deformation characteristics and fatigue behaviors of Hadfield manganese steel have been investigated by means of its ability to memorize strain and stress history. Detailed studies were performed on the strain-controlled low cycle fatigue (LCF) and stress-controlled high cycle fatigue (HCF). Initial cyclic hardening to saturation or peak stress followed by softening to fracture occurred in LCF. Internal stress made the dominant contribution to the fatigue crack propagation until failure. Effective stress evolution revealed the existence of C–Mn clusters with short-range ordering in Hadfield manganese steel and demonstrated that the interaction between C atoms in the C–Mn cluster and dislocation was essential for its cyclic hardening. The developing/developed dislocation cells and stacking faults were the main cyclic deformation microstructures on the fractured sample surface in LCF and HCF, which manifested that fatigue failure behavior of Hadfield manganese steel was induced by plastic deformation during strain-controlled or stress-controlled testing.

The construction of irradiated material examination facility

International Nuclear Information System (INIS)

Ro, Seung Gy; Lee, Key Soon; Herr, Young Hoi

1990-03-01

A detail design of the examination process, the hot cell facility and the annexed facility of the irradiated material examination facility (IMEF) which will be utilized to examine and evaluate physical and mechanical properties of neutron-irradiated materials, has been performed. Also a start-up work of the underground structure construction has been launched out. The project management and tasks required for the license application were duly carried out. The resultant detail design data will be used for the next step. (author)

Remote Operation and Maintenance Demonstration Facility at ORNL

International Nuclear Information System (INIS)

Harvey, H.W.; Floyd, S.D; Kuban, D.P.; Singletary, B.H.; Stradley, J.G.

1978-01-01

The Remote Operation and Maintenance Facility is a versatile facility arranged to mock-up various hot-cell configurations. Modular units of simulated shielding and viewing windows were built to provide flexibility in arrangement. The facility is fully equipped with hoists, manipulators, television, and the other basic equipment and services necessary to provide capability for both remote operation and maintenance of several selected functional process equipment groups. 6 figures

Direct Connect Supersonic Combustion Facility (Research Cell 22)

Data.gov (United States)

Federal Laboratory Consortium — Description: RC22 is a continuous-flow, direct-connect supersonic-combustion research facility that is capable of simulating flight conditions from Mach 3.0 to Mach...

Roll-to-Roll Inkjet Printing and Photonic Sintering of Electrodes for ITO Free Polymer Solar Cell Modules and Facile Product Integration

DEFF Research Database (Denmark)

Angmo, Dechan; Larsen-Olsen, Thue Trofod; Jørgensen, Mikkel

2013-01-01

Small polymer solar cell modules that are manufactured without indium-tin-oxide using only roll-to-roll printing and coating techniques under ambient conditions enable facile integration into a simple demonstrator (for example a laser pointer). Semitransparent front electrode grid structures prep...

Inhibition of intestinal radiocaesium absorption from Chernobyl contaminated whey by hexacyanoferrates(II) in pigs

International Nuclear Information System (INIS)

Dresow, B.; Asmus, J.; Fischer, R.; Nielsen, P.; Heinrich, H.C.

1993-01-01

The inhibition of radiocaesium transfer from Chernobyl contaminated whey powder to the pork and liver of fattening pigs using various dosages of different hexacyanoferrate (II) compounds (HCF) was studied under normal feeding conditions. Increasing amounts of all three hexacyanoferates tested resulted in a dose-dependent reduction in the 134+137 Cs activity concentration in all of the tissues sampled. KFe[Fe(CN) 6 ] and NE 4 Fe(CN) 6 ] were effective to the same extent while Fe 4 [Fe(CN) 6 ] 3 was less effective at dosages of 1-3 g d -1 HCF. Administration of 10 g d -1 HCF resulted in an almost complete inhibition (>99%) of intestinal radiocaesium absorption for all three compounds. (Author)

Sphingosine-1-Phosphate (S1P)-Related Response of Human Conjunctival Fibroblasts After Filtration Surgery for Glaucoma.

Science.gov (United States)

Aoyama-Araki, Yuka; Honjo, Megumi; Uchida, Takatoshi; Yamagishi, Reiko; Kano, Kuniyuki; Aoki, Junken; Aihara, Makoto

2017-04-01

To investigate levels of sphingosine-1-phosphate (S1P) in aqueous fluid samples taken before and after filtration surgery and S1P-induced human conjunctival fibroblast (HCF) responses. Levels of S1P and its related sphingophospholipids in aqueous fluid obtained immediately before and after filtration surgery were determined by liquid chromatography-tandem mass spectrometry. HCFs were used for all in vitro experiments. The expression of five S1P receptor subtypes in HCFs was examined by quantitative real-time PCR. The effect of S1P and receptor-specific antagonists on HCF viability and cell migration was assessed by WST-1 assay and scratch migration assay, respectively. Differentiation to myofibroblasts and extracellular matrix production was evaluated by examining changes in F-actin, α-smooth muscle actin (αSMA), and collagen expression with immunocytochemistry, Western blotting, and collagen accumulation assay, respectively. No significant S1P levels in the aqueous fluid samples were detectable immediately before surgery, but postoperative levels of several lysophospholipids, including S1P, dehydro-S1P, and sphingosine, were significantly increased to bioactive concentrations in aqueous fluid in the blebs (P S1P receptor subtypes was detected in HCFs. Although S1P levels did not influence HCF proliferation, S1P enhanced cell migration, which could be inhibited by the S1P2 antagonist JTE 013. F-actin, αSMA, and collagen expression was significantly increased by S1P stimulation and was reduced by JTE 013. Bioactive S1P concentrations were present in the aqueous fluid at the end of filtration surgery. S1P activated HCFs via S1P2 receptors. These results revealed the potential of S1P2 antagonists in preventing scarring after glaucoma filtration surgery.

Regional energy facility siting analysis

International Nuclear Information System (INIS)

Eberhart, R.C.; Eagles, T.W.

1976-01-01

Results of the energy facility siting analysis portion of a regional pilot study performed for the anticipated National Energy Siting and Facility Report are presented. The question of cell analysis versus site-specific analysis is explored, including an evaluation of the difference in depth between the two approaches. A discussion of the possible accomplishments of regional analysis is presented. It is concluded that regional sitting analysis could be of use in a national siting study, if its inherent limits are recognized

FFTF/IEM [Fast Flux Test Facility/Interim Examination and Maintenance] cell fuel pin weighing system: Remote maintenance design considerations

International Nuclear Information System (INIS)

Gibbons, P.W.

1986-06-01

A Fuel Pin Weighing Machine has been developed for use in the Fast Flux Test Facility (FFTF) Interim Examination and Maintenance (IEM) Cell to assist in identifying an individual breached fuel pin from its fuel assembly pin bundle. Optimum configuration for remote maintenance was a major consideration in the design of each element of the Pin Weighing System

Post irradiation examinations cooperation and worldwide utilization of facilities

International Nuclear Information System (INIS)

Karlsson, Mikael

2009-01-01

Status of post irradiation examinations in Studsvik's facilities, cooperation and worldwide utilization of facilities, was described. Studsvik cooperate with irradiation facilities, as Halden, CEA and JAEA, as well as other hot cell facilities (examples, PSI, ITU and NFD) universities (example, the Royal Institute of Technology in Sweden) in order to be able to provide everything asked for by the nuclear community. Worldwide cooperation for effective use of expensive and highly specialized facilities is important, and the necessity of cooperation will be more and more recognized in the future. (author)

A new radioisotope facility for Thailand

International Nuclear Information System (INIS)

Horlock, K.

1997-01-01

The Thai Office of Atomic Energy for Peace (OAEP) is planning a new Nuclear Research Centre which will be located at Ongkharak, a greenfield site some 100 km North of Bangkok. General Atomics (GA) has submitted a bid for a turnkey contract for the core facilities comprising a Reactor to be supplied by GA, an Isotope Production Facility supplied by ANSTO and a Waste Processing and Storage Facility to be supplied by Hitachi through Marubeni. The buildings for these facilities will be provided by Raytheon, the largest constructor of nuclear facilities in the USA. The proposed Isotope Facility will consist of a 3000 m 2 building adjacent to the reactor with a pneumatic radioisotope transfer system. Hot cells, process equipment and clean rooms will be provided, as well as the usual maintenance and support services required for processing radiopharmaceutical and industrial products. To ensure the highest standards of product purity the processing areas will be supplied with clean air and operated at slightly positive pressure. The radioisotopes to be manufactured include Phosphorus 32 (S-32 [n,p]P-32), I-131(Te-130 [n,g]Te-131[p]I-131) for bulk, diagnostic capsules and therapeutic capsules, Iridium 192 (Ir-191[n,g]Ir-192) wire for radiotherapy and discs for industrial radiography sources and bulk Iodine 125 (Xe-124[n,g]Xe-125[β]I-125 for radioimmunoassay. The bid includes proposals for training OAEP staff during design and development at ANSTO's radioisotope facilities, and during construction and commissioning in Thailand. The entire project is planned to take four years with commencement anticipated in early 1997. The paper will describe the development of the design of the hot-cells, process equipment, building layout and ventilation and other services

Characterization report for Building 301 Hot Cell Facility

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-07-01

During the period from October, 1997, through March, 1998, ANL-E Health Physics conducted a pre-D and D characterization of Building 301, referred to as the Hot Cell Facility. While primary emphasis was placed on radiological evaluation, the presence of non-nuclear hazardous and toxic material was also included in the scope of the characterization. This is one of the early buildings on the ANL-E site, and was heavily used in the 1950`s and 1960`s for various nuclear reaction and reactor design studies. Some degree of cleanup and contamination fixation was done in the 1970`s, so that the building could be used with a minimum of risk of personnel contamination. Work records are largely nonexistent for the early history of the building, so that any assumptions about extent and type of contamination had to be kept very open in the survey planning process. The primary contaminant was found to be painted-over Cs-137 embedded in the concrete floors, although a variety of other nuclides consistent with the work said to have been performed were found in smaller quantities. Due to leaks and drips through the floor, a relatively modest amount of soil contamination was found in the service trench under the building, not penetrating deeply. Two contaminated, disconnected drain lines leaving the building could not be traced by site records, and remain a problem for remediation. The D and D Characterization Plan was fulfilled.

Characterization report for Building 301 Hot Cell Facility

International Nuclear Information System (INIS)

1998-07-01

During the period from October, 1997, through March, 1998, ANL-E Health Physics conducted a pre-D and D characterization of Building 301, referred to as the Hot Cell Facility. While primary emphasis was placed on radiological evaluation, the presence of non-nuclear hazardous and toxic material was also included in the scope of the characterization. This is one of the early buildings on the ANL-E site, and was heavily used in the 1950's and 1960's for various nuclear reaction and reactor design studies. Some degree of cleanup and contamination fixation was done in the 1970's, so that the building could be used with a minimum of risk of personnel contamination. Work records are largely nonexistent for the early history of the building, so that any assumptions about extent and type of contamination had to be kept very open in the survey planning process. The primary contaminant was found to be painted-over Cs-137 embedded in the concrete floors, although a variety of other nuclides consistent with the work said to have been performed were found in smaller quantities. Due to leaks and drips through the floor, a relatively modest amount of soil contamination was found in the service trench under the building, not penetrating deeply. Two contaminated, disconnected drain lines leaving the building could not be traced by site records, and remain a problem for remediation. The D and D Characterization Plan was fulfilled

Remote Decontamination Facility and Repair Station for hot-cell manipulators

International Nuclear Information System (INIS)

Ryz, M.A.

1977-01-01

Increasingly high radiation levels on manipulators at the Whiteshell Nuclear Research Establishment, Pinawa, Manitoba, Canada, necessitated design and construction of a Remote Decontamination Facility and Repair Station. This facility reduces radiation levels on manipulators by an order of magnitude over previous hand decontamination techniques. The reduced radiation levels have allowed superior manipulator repair and maintenance, resulting in 50% fewer manipulator breakdowns

2015 In-Situ Gamma-Ray Assay of the West Cell Line in the 235-F Plutonium Fuel Form Facility

Energy Technology Data Exchange (ETDEWEB)

Brand, A. D. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Aucott, T. J. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); DiPrete, D. P. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

2016-02-01

In November and December 2015, scientists from SRNL took a series of in-situ gamma-ray measurements through the windows in front of Cells 6-9 on the west line of the PuFF facility using a shielded, 120% high-purity germanium detector. The detector efficiency was estimated using a combination of MCNP simulations and empirical measurements. Where possible, the distribution of the Pu-238 in the cells was determined using the Germanium Gamma-ray Imager (GeGI). This distribution was then fed into the MCNP model to quantify the Pu-238 in each cell. Data analysis was performed using three gamma rays emitted by Pu-238 (99.85 keV, 152.7 keV, and 766.4 keV) providing three independent estimates of the mass of Pu-238 holdup in each of the cells.

Development of remote handling technology for nuclear fuel cycle facilities in Japan

International Nuclear Information System (INIS)

Maekawa, Hiromichi; Sakai, Akira; Miura, Noriaki; Kozaka, Tetsuo; Hamada, Takashi

2015-01-01

Remote handling technology has been systematically developed for nuclear fuel cycle facilities in Japan since 1970s, primarily in parallel with the development of reprocessing and HLLW (High Level Liquid Waste) vitrification process. In case of reprocessing and vitrification process to handle highly radioactive and hazardous materials, the most of components are installed in the radiation shielded hot cells and operators are not allowed to enter the work area in the cells for operation and maintenance. Therefore, a completely remote handling system is adopted for the cells to reduce radiation doses of operators and increase the availability of the facility. The hot cells are generally designed considering the scale of components (laboratory, demonstration, or full-scale), the function of the systems (chemical process, material handling, dismantling, decontamination, or chemical analysis), and the environmental conditions (radiation dose rate, airborne concentration, surface contamination, or fume/mist/dust). Throughout our domestic development work for remote handling technology, the concept of the large scale integrated cell has been adopted rather than a number of small scale separated cells, for the reasons to reduce the total installation space and the number of remote handling equipment required for the each cell as much as possible. In our domestic remote maintenance design, several new concepts have been developed, tested, and demonstrated in the Tokai Virtrification Facility (TVF) and the Rokkasho HLLW Vitrification and Storage Facility (K-facility). Layout in the hot cells, the performance of remote handling equipment, and the structure of the in-cell components are important factors for remote maintenance design. In case of TVF (hot tests started in 1995), piping and vessels are prefabricated in the rack modules and installed in two lines on both sides of the cell. These modules are designed to be remotely replaced in the whole rack. Two overhead cranes

Advanced facilities for radiochemistry at Harwell

International Nuclear Information System (INIS)

1985-01-01

The leaflets in this folder describe the latest addition to Harwell's active handling capability. This is a high level alpha, beta, gamma facility designed specifically for undertaking chemical research and development work. It is based on using high integrity containment boxes which are housed in concrete shielded enclosures. The active boxes can be removed and transferred remotely to a support area where they, and any associated equipment, can be decontaminated and serviced whilst a new fully commissioned box can be readily brought into service. The facility fulfills the principle of ALARA and is sufficiently flexible to accommodate a wide range of active handling requirements. It is supported by a suite of medium active handling cells, radiochemical laboratories and, as necessary, facilities of other scientific and engineering disciplines. The leaflets are: report on conceptual aspects; Techsheet 'Remote handling facility - Salient information'; Techsheet 'Project capabilities'; and 4 sheets of diagrams showing details of the facility. (U.K.)

Very Low Activity Waste Disposal Facility Recently Commissioned as an Extension of El Cabril LILW Disposal Facility in Spain

International Nuclear Information System (INIS)

Zuloaga, P.; Navarro, M.

2009-01-01

This paper describes the Very Low Activity Radioactive Waste (VLLW) disposal facility, designed, built and operated by ENRESA as a part of El Cabril LILW disposal facility. El Cabril facility was commissioned in 1992 and has 28 concrete vaults with an internal volume of 100,000 m 3 , as well as waste treatment systems and waste characterization laboratories. The total needs identified in Spain for LILW disposal are of some 176,000 m 3 , of which around 120,000 m3 might be classified as VLLW This project was launched in 2003 and the major licensing steps have been town planning license (2003), construction authorization (after Environmental Impact Statement and report from Nuclear Safety Council-CSN, 2006), and Operations Authorization (after report from CSN, July 2008). The new VLLW disposal facility has a capacity for 130,000 meters cube in four disposal cells of approximately the same size. Only the first cell has been built. The design of the barriers is based on the European Directive for elimination of dangerous waste and consists of a clay layer 1 m, 3 cm geo-bentonite films, and 4 mm HDPE film. In order to minimize leachate volumes collected and help a good monitoring of the site, each cell is divided into different sections, which are protected during operation -before placing a provisional HDPE capping- by a light shelter and where leachate collection is segregated from other sections. (authors)

Cytotoxicity and apoptotic inducibility of Vitex agnus-castus fruit extract in cultured human normal and cancer cells and effect on growth.

Science.gov (United States)

Ohyama, Kunio; Akaike, Takenori; Hirobe, Chieko; Yamakawa, Toshio

2003-01-01

A crude extract was prepared with ethanol from dried ripened Vitex agnus-castus fruits growing in Israel (Vitex extract). Cytotoxicity of the extract against human uterine cervical canal fibroblast (HCF), human embryo fibroblast (HE-21), ovarian cancer (MCF-7), cervical carcinoma (SKG-3a), breast carcinoma (SKOV-3), gastric signet ring carcinoma (KATO-III), colon carcinoma (COLO 201), and small cell lung carcinoma (Lu-134-A-H) cells was examined. After culture for 24 h (logarithmic growth phase) or 72 h (stationary growth phase), the cells were treated with various concentrations of Vitex extract. In both growth phases, higher growth activity of cells and more cytotoxic activity of Vitex extract were seen. The cytotoxic activity against stationary growth-phase cells was less than that against logarithmic growth-phase cells. DNA fragmentation of Vitex extract-treated cells was seen in SKOV-3, KATO-III, COLO 201, and Lu-134-A-H cells. The DNA fragmentation in Vitex extract-treated KATO-III cells was inhibited by the presence of the antioxidative reagent pyrrolidine dithiocarbamate or N-acetyl-L-cysteine (NAC). Western blotting analysis showed that in Vitex extract-treated KATO-III cells, the presence of NAC also inhibited the expression of heme oxygenase-1 and the active forms of caspases-3, -8 and -9. It is concluded that the cytotoxic activity of Vitex extract may be attributed to the effect on cell growth, that cell death occurs through apoptosis, and that this apoptotic cell death may be attributed to increased intracellular oxidation by Vitex extract treatment.

Construction of irradiated material examination facility-basic design

International Nuclear Information System (INIS)

Ro, Seung Gy; Kim, Eun Ka; Hong, Gye Won; Herr, Young Hoi; Hong, Kwon Pyo; Lee, Myeong Han; Baik, Sang Youl; Choo, Yong Sun; Baik, Seung Je

1989-02-01

The basic design of the hot cell facility which has the main purpose of doing mechanical and physical property tests of irradiated materials, the examination process, and the annexed facility has been made. Also basic and detall designs for the underground excavation work have been performed. The project management and tasks required for the license application have been carried out in due course. The facility is expected to be completed by the end of 1992, if the budgetary support is sufficient. (Author)

Preliminary design of a Tandem-Mirror-Next-Step facility

International Nuclear Information System (INIS)

Damm, C.C.; Doggett, J.N.; Bulmer, R.H.

1980-01-01

The Tandem-Mirror-Next-Step (TMNS) facility is designed to demonstrate the engineering feasibility of a tandem-mirror reactor. The facility is based on a deuterium-tritium (D-T) burning, tandem-mirror device with a fusion power output of 245 MW. The fusion power density in the central cell is 2.1 MW/m 3 , with a resultant neutron wall loading of 0.5 MW/m 2 . Overall machine length is 116 m, and the effective central-cell length is 50.9 m. The magnet system includes end cells with yin-yang magnets to provide magnetohydrodynamic (MHD) stability and thermal-barrier cells to help achieve a plasma Q of 4.7 (where Q = fusion power/injected power). Neutral beams at energies up to 200 keV are used for plasma heating, fueling, and barrier pumping. Electron cyclotron resonant heating at 50 and 100 GHz is used to control the electron temperature in the barriers. Based on the resulting engineering design, the overall cost of the facility is estimated to be just under $1 billion. Unresolved physics issues include central-cell β-limits against MHD ballooning modes (the assumed reference value of β exceeds the current theory-derived limit), and the removal of thermalized α-particles from the plasma

A new facility for advanced rocket propulsion research

Science.gov (United States)

Zoeckler, Joseph G.; Green, James M.; Raitano, Paul

1993-06-01

A new test facility was constructed at the NASA Lewis Research Center Rocket Laboratory for the purpose of conducting rocket propulsion research at up to 8.9 kN (2000 lbf) thrust, using liquid oxygen and gaseous hydrogen propellants. A laser room adjacent to the test cell provides access to the rocket engine for advanced laser diagnostic systems. The size and location of the test cell provide the ability to conduct large amounts of testing in short time periods, with rapid turnover between programs. These capabilities make the new test facility an important asset for basic and applied rocket propulsion research.

Comparison of cardiovascular protective effects of tropical seaweeds, Kappaphycus alvarezii, Caulerpa lentillifera, and Sargassum polycystum, on high-cholesterol/high-fat diet in rats.

Science.gov (United States)

Matanjun, Patricia; Mohamed, Suhaila; Muhammad, Kharidah; Mustapha, Noordin Mohamed

2010-08-01

This study was designed to investigate the comparative in vivo cardiovascular protective effects of red, green, and brown tropical seaweeds, namely, Kappaphycus alvarezii (or Eucheuma cottonii), Caulerpa lentillifera, and Sargassum polycystum, in rats fed on high-cholesterol/high-fat (HCF) diets. Male Sprague-Dawley rats (weighing 260-300 g) on the HCF diet had significantly increased body weight, plasma total cholesterol (TC), plasma low-density lipoprotein cholesterol (LDL-C), plasma triglycerides (TG), lipid peroxidation, and erythrocyte glutathione peroxidase (GSH-Px) and superoxide dismutase levels after 16 weeks. Supplementing 5% seaweeds to HCF diet significantly reduced plasma TC (-11.4% to -18.5%), LDL-C (-22% to -49.3%), and TG (-33.7% to -36.1%) levels and significantly increased HDL-C levels (16.3-55%). Among the seaweeds, S. polycystum showed the best anti-obesity and blood GSH-Px properties, K. alvarezii showed the best antihyperlipemic and in vivo antioxidation effects, and C. lentillifera was most effective at reducing plasma TC. All seaweeds significantly reduced body weight gain, erythrocyte GSH-Px, and plasma lipid peroxidation of HCF diet rats towards the values of normal rats.

Fire Hazard Analysis for the Cold Vacuum Drying facility (CVD) Facility

CERN Document Server

Singh, G

2000-01-01

The CVDF is a nonreactor nuclear facility that will process the Spent Nuclear Fuels (SNF) presently stored in the 105-KE and 105-KW SNF storage basins. Multi-canister overpacks (MCOs) will be loaded (filled) with K Basin fuel transported to the CVDF. The MCOs will be processed at the CVDF to remove free water from the fuel cells (packages). Following processing at the CVDF, the MCOs will be transported to the CSB for interim storage until a long-term storage solution can be implemented. This operation is expected to start in November 2000. A Fire Hazard Analysis (FHA) is required for all new facilities and all nonreactor nuclear facilities, in accordance with U.S. Department of Energy (DOE) Order 5480.7A, Fire Protection. This FHA has been prepared in accordance with DOE 5480.7A and HNF-PRO-350, Fire Hazard Analysis Requirements. Additionally, requirements or criteria contained in DOE, Richland Operations Office (RL) RL Implementing Directive (RLID) 5480.7, Fire Protection, or other DOE documentation are cite...

Calculation Package for the Analysis of Performance of Cells 1-6, with Underdrain, of the Environmental Management Waste Management Facility Oak Ridge, Tennessee

Energy Technology Data Exchange (ETDEWEB)

Gonzales D.

2010-03-30

This calculation package presents the results of an assessment of the performance of the 6 cell design of the Environmental Management Waste Management Facility (EMWMF). The calculations show that the new cell 6 design at the EMWMF meets the current WAC requirement. QA/QC steps were taken to verify the input/output data for the risk model and data transfer from modeling output files to tables and calculation.

Integrated biofuel facility, with carbon dioxide consumption and power generation

Energy Technology Data Exchange (ETDEWEB)

Powell, E.E.; Hill, G.A. [Saskatchewan Univ., Saskatoon, SK (Canada). Dept. of Chemical Engineering

2009-07-01

This presentation provided details of an economical design for a large-scale integrated biofuel facility for coupled production of bioethanol and biodiesel, with carbon dioxide capture and power generation. Several designs were suggested for both batch and continuous culture operations, taking into account all costs and revenues associated with the complete plant integration. The microalgae species Chlorella vulgaris was cultivated in a novel photobioreactor (PBR) in order to consume industrial carbon dioxide (CO{sub 2}). This photosynthetic culture can also act as a biocathode in a microbial fuel cell (MFC), which when coupled to a typical yeast anodic half cell, results in a complete biological MFC. The photosynthetic MFC produces electricity as well as valuable biomass and by-products. The use of this novel photosynthetic microalgae cathodic half cell in an integrated biofuel facility was discussed. A series of novel PBRs for continuous operation can be integrated into a large-scale bioethanol facility, where the PBRs serve as cathodic half cells and are coupled to the existing yeast fermentation tanks which act as anodic half cells. These coupled MFCs generate electricity for use within the biofuel facility. The microalgae growth provides oil for biodiesel production, in addition to the bioethanol from the yeast fermentation. The photosynthetic cultivation in the cathodic PBR also requires carbon dioxide, resulting in consumption of carbon dioxide from bioethanol production. The paper also discussed the effect of plant design on net present worth and internal rate of return. tabs., figs.

Final design of ITER port plug test facility

Energy Technology Data Exchange (ETDEWEB)

Cerisier, Thierry, E-mail: thierry.cerisier@yahoo.fr [ITER Organization, Route de Vinon-sur-Verdon, CS 90046, St Paul-lez-Durance Cedex, 13067 (France); Levesy, Bruno [ITER Organization, Route de Vinon-sur-Verdon, CS 90046, St Paul-lez-Durance Cedex, 13067 (France); Romannikov, Alexander [Institution “Project Center ITER”, Kurchatov sq. 1, Building 3, Moscow 123182 (Russian Federation); Rumyantsev, Yuri [JSC “Cryogenmash”, Moscow reg., Balashikha 143907 (Russian Federation); Cordier, Jean-Jacques; Dammann, Alexis [ITER Organization, Route de Vinon-sur-Verdon, CS 90046, St Paul-lez-Durance Cedex, 13067 (France); Minakov, Victor; Rosales, Natalya; Mitrofanova, Elena [JSC “Cryogenmash”, Moscow reg., Balashikha 143907 (Russian Federation); Portone, Sergey; Mironova, Ekaterina [Institution “Project Center ITER”, Kurchatov sq. 1, Building 3, Moscow 123182 (Russian Federation)

2016-11-01

Highlights: • We introduce the port plug test facility (purpose and status of the design). • We present the PPTF sub-systems. • We present the environmental and functional tests. • We present the occupational and nuclear safety functions. • We conclude on the achievements and next steps. - Abstract: To achieve the overall ITER machine availability target, the availability of diagnostics and heating port plugs shall be as high as 99.5%. To fulfill this requirement, it is mandatory to test the port plugs at operating temperature before installation on the machine and after refurbishment. The ITER port plug test facility (PPTF) is composed of several test stands that can be used to test the port plugs whereas at the end of manufacturing (in a non-nuclear environment), or after refurbishment in the ITER hot cell facility. The PPTF provides the possibility to perform environmental (leak tightness, vacuum and thermo-hydraulic performances) and functional tests (radio frequency acceptance tests, behavior of the plugs’ steering mechanism and calibration of diagnostics) on upper and equatorial port plugs. The final design of the port plug test facility is described. The configuration of the standalone test stands and the integration in the hot cell facility are presented.

Waste reduction efforts through the evaluation and procurement of a digital camera system for the Alpha-Gamma Hot Cell Facility at Argonne National Laboratory-East

International Nuclear Information System (INIS)

Bray, T. S.; Cohen, A. B.; Tsai, H.; Kettman, W. C.; Trychta, K.

1999-01-01

The Alpha-Gamma Hot Cell Facility (AGHCF) at Argonne National Laboratory-East is a research facility where sample examinations involve traditional photography. The AGHCF documents samples with photographs (both Polaroid self-developing and negative film). Wastes generated include developing chemicals. The AGHCF evaluated, procured, and installed a digital camera system for the Leitz metallograph to significantly reduce labor, supplies, and wastes associated with traditional photography with a return on investment of less than two years

A PBE hybrid functional study of blue-shifting and red-shifting hydrogen bonds in p hydrocarbons

Directory of Open Access Journals (Sweden)

Boaz Galdino de Oliveira

2009-07-01

Full Text Available This study examines a selected group of p hydrocarbon complexes, represented by C2H4•••HCF3, C2H2•••HCF3, C2H4•••HCF3 and C2H2•••HCF3, from a theoretical point of view. From BPBE/6-311++G(d,p calculations, the geometrical results of these complexes revealed an elongation and shortening of the H—C bond lengths of chloroform (HCCl3 and fluoroform (HCF3, respectively. In terms of the infrared spectrum, the analysis of stretch frequencies revealed that the variations in the H—C modes are essentially recognized as red and blue-shifting modes. For the purposes of understanding the two vibrational phenomena of the p hydrocarbon complexes studied here, PBE/6-311++G(d,p calculations were carried out and partitioning of atomic charges derived from the ChelpG algorithm were also used. A theoretical justification of red- and blue-shift effects was drawn up using charge-transfer analysis, which is manifested in the p bonds of acetylene and ethylene to chloroform (H—CCl3 and fluoroform (H—CF3, respectively. Finally, a further debate regarding the distinct polarizability power of chloroform and fluoroform is presented, concluding that, in comparison with fluoroform, chloroform possesses the requisite features for conventional proton donors and a red-shift is therefore observed in the C2H4•••HCCl3 and C2H2•••HCCl3 complexes.

UTN's gamma irradiation facility: design and concept

International Nuclear Information System (INIS)

Mohamad Noor Mohamad Yunus

1986-01-01

UTN is building a multipurpose gamma irradiation facility which compromises of research and pilot scale irradiation cells in The Fifth Malaysia Plan. The paper high-lights the basic futures of the facility in terms of its design and selection including layout sketches. Plant performances and limitations are discussed. Plants safety is briefly highlighted in block diagrams. Lastly, a typical specification brief is tabled in appendix for reference purposes. (author)

Development of a low-energy radioactive ion beam facility for the MARA separator

Energy Technology Data Exchange (ETDEWEB)

Papadakis, Philippos, E-mail: philippos.papadakis@jyu.fi; Moore, Iain; Pohjalainen, Ilkka; Sarén, Jan; Uusitalo, Juha [University of Jyväskylä, Department of Physics (Finland)

2016-12-15

A low-energy radioactive ion beam facility for the production and study of nuclei produced close to the proton drip line is under development at the Accelerator Laboratory of the University of Jyväskylä, Finland. The facility will take advantage of the mass selectivity of the recently commissioned MARA vacuum-mode mass separator. The ions selected by MARA will be stopped and thermalised in a small-volume gas cell prior to extraction and further mass separation. The gas cell design allows for resonance laser ionisation/spectroscopy both in-gas-cell and in-gas-jet. The facility will include experimental setups allowing ion counting, mass measurement and decay spectroscopy.

Studsvik thermal neutron facility

International Nuclear Information System (INIS)

Pettersson, O.A.; Larsson, B.; Grusell, E.; Svensson, P.

1992-01-01

The Studsvik thermal neutron facility at the R2-0 reactor originally designed for neutron capture radiography has been modified to permit irradiation of living cells and animals. A hole was drilled in the concrete shielding to provide a cylindrical channel with diameter of 25.3 cm. A shielding water tank serves as an entry holder for cells and animals. The advantage of this modification is that cells and animals can be irradiated at a constant thermal neutron fluence rate of approximately 10 9 n cm -2 s -1 (at 100 kW) without stopping and restarting the reactor. Topographic analysis of boron done by neutron capture autoradiography (NCR) can be irradiated under the same conditions as previously

Commissioning and early operating experience with the Fermilab horizontal test facility

Energy Technology Data Exchange (ETDEWEB)

Carcagno, R.; Chase, B.; Harms, E.; Hocker, A.; Prieto, P.; Reid, J.; Rowe, A.; Theilacker, J.; Votava, M.; /Fermilab

2007-10-01

Fermilab has constructed a facility for testing dressed superconducting radiofrequency (RF) cavities at 1.8 K with high-power pulsed RF. This test stand was designed to test both 9-cell 1.3 GHz TESLA-style cavities and 9-cell 3.9 GHz cavities being built by Fermilab for DESY's TTF-FLASH facility. An overview of the test stand and a description of its initial commissioning is described here.

Plasma-Materials Interactions Test Facility

International Nuclear Information System (INIS)

Uckan, T.

1986-11-01

The Plasma-Materials Interactions Test Facility (PMITF), recently designed and constructed at Oak Ridge National Laboratory (ORNL), is an electron cyclotron resonance microwave plasma system with densities around 10 11 cm -3 and electron temperatures of 10-20 eV. The device consists of a mirror cell with high-field-side microwave injection and a heating power of up to 0.8 kW(cw) at 2.45 GHz. The facility will be used for studies of plasma-materials interactions and of particle physics in pump limiters and for development and testing of plasma edge diagnostics

STARFIRE remote maintenance and reactor facility concept

International Nuclear Information System (INIS)

Graumann, D.W.; Field, R.E.; Lutz, G.R.; Trachsel, C.A.

1981-01-01

A total remote maintenance facility has been designed for all equipment located within the reactor building and hot cell, although operational flexibility has been provided by design of the reactor shielding such that personnel access into the reactor building within 24 hours after reactor shutdown is possible. The reactor design permits removal and replacement of all components if necessary, however, the vacuum pumps, isolation valves and blanket require scheduled, routine maintenance. Reactor scheduled maintenance does not dominate annual plant downtime, therefore, several scheduled operations can be added without affecting reactor availability. The maintenance facilities consist of the reactor building, the hot cell, the reactor service area and the remote maintenance control room. The reactor building contains the reactor, selected support system modules, and required maintenance equipment. The reactor and the support systems are maintained with (1) equipment that is mounted on a monorail system; (2) overhead cranes; and (3) bridge-mounted electromechanical manipulators. The hot cell is located outside of the reactor building to localize contamination products and permit independent operation. An equipment air lock connects the reactor building to the hot cell

Modelling of multiphase flow in concrete cells of the radioactive waste storage facility at El Cabril (Spain)

International Nuclear Information System (INIS)

Chaparro, M.C.; Saaltink, M.W.

2015-01-01

El Cabril is the low and intermediate level radioactive waste disposal facility for Spain. After sealing the cells that stored the radioactive waste, water was collected from a drainpipe, indicating the flow of water within the cell. A hypothesis had been proposed to explain this phenomenon which consists of capillary rise from groundwater and evaporation and condensation within the cell produced by temperature gradients caused by seasonal temperature fluctuations outside. To corroborate this hypothesis a 2D numerical model was made taking into account all relevant processes such as multiphase flow and heat transport. Data were used measured by sensors in the cells and data from laboratory test. There is a good agreement between the temperature measured by the sensors and the ones calculated by the model. The model shows a drying of the concrete at the hot side (that is the wall during summer and the container during winter). The concrete is saturated with water at the cold side (that is the container during summer and the wall in winter), leading to runoff of water to the drainpipe. The flux at this drainpipe occurred in the two yearly periods, being higher in winter than in summer. (authors)

External irradiation facilities open for biological studies - progress in july 2005

International Nuclear Information System (INIS)

Gaillard-Lecanu, E.; Authier, N.; Verrey, B.; Bailly, I.; Bordy, J.M.; Coffigny, H.; Cortela, L.; Duval, D.; Leplat, J.J.; Poncy, J.L.; Testard, I.; Thuret, J.Y.

2005-01-01

The Life Science Division of the Atomic Energy Commission is making an inventory of the various radiation sources accessible for investigation on the biological effects of ionizing radiation. In this field, a wide range of studies is being carried out at the Life Science Division, attempting to characterize the kind of lesions with their early biological consequences (on the various cell compartments) and their late biological consequences (deterministic or stochastic effects), in relation to the radiation type and dose, especially at low doses. Several experimental models are available: plants, bacteria, eukaryotic cells from yeast up to mammalian cells and in vivo studies, mostly on rodents, in order to characterize the somatic late effects and the hereditary effects. Due to the significant cost of these facilities, also to their specific properties (nature of the radiation, dose and dose rate, possible accuracy of the irradiation at the molecular level), the closeness is no longer the only criteria for biologists to make a choice. The current evolution is to set up irradiation infrastructures combining ionizing radiation sources themselves and specific tools dedicated to biological studies: cell or molecular biology laboratories, animal facilities. The purpose, in this new frame, is to provide biologists with the most suitable facilities, and, if possible, to change these facilities according to requirements in radiobiology. In this report, the basics of interactions of ionizing radiation with biological tissues are briefly introduced, followed by a presentation of some of the facilities available for radiobiological studies especially at CEA. This panorama is not a comprehensive one, new data will be included as they advance, whether reporting existing facilities or if a new one is developed. (authors)

Operation manual for the INEL on-line mass-separator facility

International Nuclear Information System (INIS)

Anderl, R.A.

1984-06-01

This report is an operation manual for an on-line mass-separator facility which is located in Building 661 at the Test Reactor Area of the Idaho National Engineering Laboratory. The facility provides mass-separated sources of short-lived fission-product radionuclides whose decay properties can be studied using a variety of nuclear spectroscopic techniques. This facility is unique in that it utilizes the gas-jet technique to transport fission products from a 252 Cf source located in a hot cell to the ion source of the mass separator. This document includes the following: (a) a detailed description of the facility, (b) identification of equipment hazards and safety controls, (c) detailed operating procedures for startup, continuous operation and shutdown, (d) operating procedures for the californium hot cell, and (e) an operator's manual for the automated moving tape collector/data acquisition system. 7 references, 16 figures, 8 tables

A Bioinformatics Facility for NASA

Science.gov (United States)

Schweighofer, Karl; Pohorille, Andrew

2006-01-01

Building on an existing prototype, we have fielded a facility with bioinformatics technologies that will help NASA meet its unique requirements for biological research. This facility consists of a cluster of computers capable of performing computationally intensive tasks, software tools, databases and knowledge management systems. Novel computational technologies for analyzing and integrating new biological data and already existing knowledge have been developed. With continued development and support, the facility will fulfill strategic NASA s bioinformatics needs in astrobiology and space exploration. . As a demonstration of these capabilities, we will present a detailed analysis of how spaceflight factors impact gene expression in the liver and kidney for mice flown aboard shuttle flight STS-108. We have found that many genes involved in signal transduction, cell cycle, and development respond to changes in microgravity, but that most metabolic pathways appear unchanged.

Actinide Separation Demonstration Facility, Tarapur

International Nuclear Information System (INIS)

Vishwaraj, I.

2017-01-01

Partitioning of minor actinide from high level waste could have a substantial impact in lowering the radio toxicity associated with high level waste as well as it will reduce the burden on geological repository. In Indian context, the partitioned minor actinide could be routed into the fast breeder reactor systems scheduled for commissioning in the near period. The technological breakthrough in solvent development has catalyzed the partitioning programme in India, leading to the setting up and hot commissioning of the Actinide Separation Demonstration Facility (ASDF) at BARC, Tarapur. The engineering scale Actinide Separation Demonstration Facility (ASDF) has been retrofitted in an available radiological hot cell situated adjacent to the Advanced Vitrification Facility (AVS). This location advantage ensures an uninterrupted supply of high-level waste and facilitates the vitrification of the high-level waste after separation of minor actinides

Operating instructions for LBL radon measurement facilities

International Nuclear Information System (INIS)

Ingersoll, J.G.

1980-06-01

This manual is intended for users of the radon-measuring facilities of the Radon Project of the Building Ventilation and Indoor Air Quality Program at Lawrence Berkeley Laboratory. The manual comprises three parts. Part 1 sets out the steps involved in collecting, transferring, and counting radon. Part 2 describes the calibration of the transfer system and of the Lucas cells in the counting system. Part 3 outlines the maintenance procedures for the facility

Overhead remote handling systems for the process facility modifications project

International Nuclear Information System (INIS)

Wiesener, R.W.; Grover, D.L.

1987-01-01

Each of the cells in the process facility modifications (PFM) project complex is provided with a variety of general purpose remote handling equipment including bridge cranes, monorail hoist, bridge-mounted electromechanical manipulator (EMM) and an overhead robot used for high efficiency particulate air (HEPA) filter changeout. This equipment supplements master-slave manipulators (MSMs) located throughout the complex to provide an overall remote handling system capability. The overhead handling equipment is used for fuel and waste material handling operations throughout the process cells. The system also provides the capability for remote replacement of all in-cell process equipment which may fail or be replaced for upgrading during the lifetime of the facility

The AWAKE Experimental Facility at CERN

CERN Document Server

Gschwendtner, E; Bracco, C; Butterworth, A; Cipiccia, S; Doebert, S; Fedosseev, V; Feldbaumer, E; Hessler, C; Hofle, W; Martyanov, M; Meddahi, M; Osborne, J; Pardons, A; Petrenko, A; Vincke, H

2014-01-01

AWAKE, an Advanced Wakefield Experiment is launched at CERN to verify the proton driven plasma wakefield acceleration concept. Proton bunches at 400 GeV/c will be extracted from the CERN SPS and sent along a 750 m long proton line to a plasma cell, a Rubidium vapour source, where the proton beam drives wakefields reaching accelerating gradients of several gigavolts per meter. A high power laser pulse will copropagate within the proton bunch creating the plasma by ionizing the (initially) neutral gas. An electron beam will be injected into the plasma cell to probe the accelerating wakefield. The AWAKE experiment will be installed in the CNGS facility. First proton beam to the plasma cell is expected by end 2016. The installation planning and the baseline parameters of the experiment are shown. The design of the experimental area and the integration of the new beam-lines as well as the experimental equipment are presented. The needed modifications of the infrastructure in the facility and a few challenges are h...

2x1 prototype plasma-electrode pockels cell (PEPC) for the National Ignition Facility

International Nuclear Information System (INIS)

Rhodes, M. A.

1996-10-01

A large aperture optical switch based on plasma electrode Pockels cell (PEPC) technology is an integral part of the National Ignition Facility (NIP) laser design. This optical switch will trap the input optical pulse in the NIF amplifier cavity for four gain passes and then switch the high-energy output optical pulse out of the cavity. The switch will consist of arrays of plasma electrode Pockels cells working in conjunction with thin-film, Brewster's angle polarizes. The 192 beams in the NIF will be arranged in 4x2 bundles. To meet the required beam-to-beam spacing within each bundle, we have proposed a NIF PEPC design based on a 4x1 mechanical module (column) which is in turn comprised of two electrically independent 2x1 PEPC units. In this paper, we report on the design a single 2x1 prototype module and experimental tests of important design issues using our single, 32 cm aperture PEPC prototype. The purpose the 2x1 prototype is to prove the viability of a 2x1 PEPC and to act, as an engineering test bed for the NIF PEPC design

Design of good manufacturing facility for sterile radioactive pharmaceuticals

International Nuclear Information System (INIS)

Shin, B.C.; Choung, W.M.; Park, S.H.; Lee, K.I.; Park, J.H.; Park, K.B.

2002-01-01

Based on the GMP codes for radiopharmaceuticals in U.K. and some advanced countries, suitable guidelines for the production facility have been established and followed them up. The facility designs were fairly modified to maintain cleanliness criteria for installation in the existing radioisotope production facilities which are installed only in radiation safety points of view. Detailed design brief was drawn up by the Hyundai Engineering staffs, on the basis of initial planning and conceptual design was carried out by authors. Hot cells were installed in preparation room for radioactive handling. As hot cells under negative air pressure are not properly airtight, the surrounding environment was designed to keep less than class 10,000. Hot cells were designed to maintain less than class 1 0,000 and partially less than class 1 00 for production of sterile products. Final products will be autoclaved for sterilization after filling. To avoid contamination by microorganisms and particles of surrounding area, air curtain with vertical laminar flow will be installed between anteroom and corridor. In a pharmaceutical environment, the main consideration is the protection of the product. Thus, work station is held above ambient pressure. However, when handling radioactive materials, air pressure for work station should be lower than in surrounding areas to protect the operators and the remainder of the facility from airborne radioactive contamination. As Radiopharmaceuticals are radioactive materials for medical use, changing room could be held higher pressure than any other zones. It is expected that the facility will be effectively used for both routine preparation and research for sterile radiopharmaceuticals. (Author)

Decommissioning of the Risoe Hot Cell facility

International Nuclear Information System (INIS)

Carlsen, H.

1993-10-01

A concise description of the current status of the decommissioning of the hot cell capacity at Risoe National Laboratory is given in this 6th periodic report covering January 1st to June 30th, 1993. All registered and safeguarded fissile material has been removed and the task of cutting and packing scrap material and experimental equipment from the concrete cell line has been completed. Concrete cells 5 and 6 have been finally cleaned and the master slave manipulators removed from them. The major part of the contamination on the shutters and shutter houses were on their horizontal planes and the main contaminant was 137 Cs. Here the surfaces were cleaned by wiping with wet cloths. The method is described. Tables illustrating the resulting contamination levels are included, the density is now low on the shutters. The method of final inn-cell cleaning is explained, and here again tables represent the resulting contamination levels. The work on ''hot spot'' removal and remote cleaning by vacuuming continues on the remaining cells. A collective dose of ca. 16.3 man-mSv was ascribed to 18 persons in the first half of 1993, arising mainly from in-cell work and waste handling. To sum up, the main results from this period are successful removal of last waste from the cells, remote cleaning of cells 2 and 3, final condition for all shutters and shutter housings and final condition for cells 5 and 6. Tables illustrate measured dose rates in detail. (AB)

Distributed Supply Coordination for Power-to-Gas Facilities Embedded in Energy Grids

NARCIS (Netherlands)

Alkano, Desti; Scherpen, Jacquelien M. A.

This paper considers hydrogen and renewable electricity from power-to-gas (PtG) facilities supplied to a gas grid, a mobility sector, and a power grid. The PtG facilities are equipped with hydrogen buffers and fuel cells. The goal is to maximize the expected profit of PtG facilities without

A Facile Droplet-Chip-Time-Resolved Inductively Coupled Plasma Mass Spectrometry Online System for Determination of Zinc in Single Cell.

Science.gov (United States)

Wang, Han; Chen, Beibei; He, Man; Hu, Bin

2017-05-02

Single cell analysis is a significant research field in recent years reflecting the heterogeneity of cells in a biological system. In this work, a facile droplet chip was fabricated and online combined with time-resolved inductively coupled plasma mass spectrometry (ICPMS) via a microflow nebulizer for the determination of zinc in single HepG2 cells. On the focusing geometric designed PDMS microfluidic chip, the aqueous cell suspension was ejected and divided by hexanol to generate droplets. The droplets encapsulated single cells remain intact during the transportation into ICP for subsequent detection. Under the optimized conditions, the frequency of droplet generation is 3-6 × 10 6 min -1 , and the injected cell number is 2500 min -1 , which can ensure the single cell encapsulation. ZnO nanoparticles (NPs) were used for the quantification of zinc in single cells, and the accuracy was validated by conventional acid digestion-ICPMS method. The ZnO NPs incubated HepG2 cells were analyzed as model samples, and the results exhibit the heterogeneity of HepG2 cells in the uptake/adsorption of ZnO NPs. The developed online droplet-chip-ICPMS analysis system achieves stable single cell encapsulation and has high throughput for single cell analysis. It has the potential in monitoring the content as well as distribution of trace elements/NPs at the single cell level.

Conceptual structure design of experimental facility for advanced spent fuel conditioning process

International Nuclear Information System (INIS)

Joo, J. S.; Koo, J. H.; Jung, W. M.; Jo, I. J.; Kook, D. H.; Yoo, K. S.

2003-01-01

A study on the advanced spent fuel conditioning process (ACP) is carring out for the effective management of spent fuels of domestic nuclear power plants. This study presents basic shielding design, modification of IMEF's reserve hot cell facility which reserved for future usage, conceptual and structural architecture design of ACP hot cell and its contents, etc. considering the characteristics of ACP. The results of this study will be used for the basic and detail design of ACP demonstration facility, and utilized as basic data for the safety evaluation as essential data for the licensing of the ACP facility

Antioxidant effect of sericin in brain and peripheral tissues of oxidative stress induced hypercholesterolemic rats

Directory of Open Access Journals (Sweden)

Meetali Deori

2016-09-01

Full Text Available This study evaluated the antioxidant effect of crude sericin extract (CSE from Antheraea assamenisis (Aa in high cholesterol fed rats. Investigation was conducted by administering graded oral dose of 0.25 and 0.5 gm/kg body weight (b.w./day of CSE for a period of 28 days. Experiments were conducted in 30 rats and were divided into five groups: normal control (NC, high cholesterol fed (HCF, HCF + 0.065 gm/kg b.w./day fenofibrate (FF, HCF + sericin 0.25 gm/kg b.w./day (LSD and HCF + sericin 0.5 gm/kg b.w./day (HSD. In brain, heart, liver, serum and kidney homogenates nitric oxide (NO, thiobarbituric acid reactive substances (TBARS, protein carbonyl content (PCC, superoxide dismutase (SOD, reduced glutathione (GSH was measured. LSD treatment prevented the alterations in GSH and PCC levels in hypercholesterolemic (HyC brain tissue homogenates of rats. CSE lowers the serum total cholesterol level in HyC rats by promoting fecal cholesterol (FC excretion. CSE increases FC level by promoting inhibition of cholesterol absorption in intestine. The endogenous antioxidant reduced significantly and the oxidative stress (OS marker TBARS level increases significantly in the peripheral tissue of HCF rats. However, the administration of LSD and HSD exhibited a good antioxidant activity by reducing the TBARS level and increasing the endogenous antioxidant in peripheral tissue. In addition, a histological examination revealed loss of normal liver and kidney architecture in cholesterol fed rats which were retained in sericin treated groups. The findings of this study suggested that CSE improves hypercholesterolemia in rats fed a HyC diet. Clinical relevance of this effect of CSE seems worthy of further studies.

Transfer tunnel transporter system for the Fuels and Materials Examination Facility

International Nuclear Information System (INIS)

Petty, J.A.; Miller, S.C.; Richards, J.T.

1981-01-01

The detail design is complete and fabrication is approximately 75% complete on the Transfer Tunnel Transporter System. This system provides material handling capability for large, bulky equipment between two hot cells in a new Breeder Reactor Program support facility, the Fuels and Materials Examination Facility. One hot cell has an air atmosphere, the other a high purity inert gas atmosphere which must be maintained during transfer operations. System design features, operational capabilities and remote recovery provisions are described

Startup of the remote laboratory-scale waste-treatment facility

International Nuclear Information System (INIS)

Knox, C.A.; Siemens, D.H.; Berger, D.N.

1981-01-01

The Remote Laboratory-Scale Waste-Treatment Facility was designed as a system to solidify small volumes of radioactive liquid wastes. The objectives in operating this facility are to evaluate solidification processes, determine the effluents generated, test methods for decontaminating the effluents, and provide radioactive solidified waste products for evaluation. The facility consists of a feed-preparation module, a waste-solidification module and an effluent-treatment module. The system was designed for remote installation and operation. Several special features for remotely handling radioactive materials were incorporated into the design. The equipment was initially assembled outside of a radiochemical cell to size and fabricate the connecting jumpers between the modules and to complete some preliminary design-verification tests. The equipment was then disassembled and installed in the radiochemical cell. When installation was completed the entire system was checked out with water and then with a nonradioactive simulated waste solution. The purpose of these operations was to start up the facility, find and solve operational problems, verify operating procedures and train personnel. The major problems experienced during these nonradioactive runs were plugging of the spray calciner nozzle and feed tank pumping failures. When these problems were solved, radioactive operations were started. This report describes the installation of this facility, its special remote design feature and the startup operations

324 Facility B-Cell quality process plan

International Nuclear Information System (INIS)

Carlson, J.L.

1998-01-01

B-Cell is currently being cleaned out (i.e., removal of equipment, fixtures and residual radioactive materials) and deactivated. TPA Milestone M-89-02 dictates that all mixed waste and equipment be removed from B-Cell by 5/31/99. The following sections describe the major activities that remain for completion of the TPA milestone. This includes: (1) Size Reduce Tank 119 and Miscellaneous Equipment. This activity is the restart of hotwork in B-Cell to size reduce the remainder of Tank 119 and other miscellaneous pieces of equipment into sizes that can be loaded into a grout container. This activity also includes the process of preparing the containers for shipment from the cell. The specific activities and procedures used are detailed in a table. (2) Load and Ship Low-Level Waste. This activity covers the process of taking a grouted LLW container from B-Cell and loading it into the cask in the REC airlock and Cask Handling Area (CHA) for shipment to the LLBG. The detailed activities and procedures for this part of cell cleanout are included in second table

The operation of post-irradiation examination facility

International Nuclear Information System (INIS)

Kim, Eun Ka; Min, Duk Ki; Lee, Young Kil

1994-12-01

The operation of post-irradiation examination facility was performed as follow. HVAC and pool water treatment system were continuously operated, and radiation monitoring in PIE facility has been carried out to maintain the facility safely. Inspection of the fuel assembly (F02) transported from Kori Unit 1 was performed in pool, and fuel rods extracted from the fuel assembly (J44) of Kori Unit 2 NPP were examined in hot cell. A part of deteriorated pipe line of drinking water was exchanged for stainless steel pipe to prevent leaking accidents. Halon gas system was also installed in the exhausting blower room for fire fighting. And IAEA inspection camera for safeguard of nuclear materials was fixed at the wall in pool area. Radiation monitoring system were improved to display the area radioactive value at CRT monitor in health physics control room. And automatic check system for battery and emergency diesel generator was developed to measure the voltage and current of them. The performance test of oxide thickness measuring device installed in hot cell for irradiated fuel rod and improvement of the device were performed, and good measuring results using standard sample were obtained. The safeguard inspection of nuclear materials and operation inspection of the facility were carried out through the annual operation inspection, quarterly IAEA inspection and quality assurance auditing. 26 tabs., 43 figs., 14 refs. (Author) .new

The new MAW scrap processing facility

International Nuclear Information System (INIS)

Kueppers, L.

1994-01-01

The shielded bunker for heat-generating waste attached to the MAW scrap processing cell will be modified and extended to comprise several MAW scrap processing cells of enhanced throughput capacity, and a new building to serve as an airlock and port for acceptance of large shipping casks (shipping cask airlock, TBS). The new facility is to process scrap from decommissioned nuclear installations, and in addition radwaste accrued at operating plants of utilities. This will allow efficient and steady use of the new MAW scrap processing facility. The planning activities for modification and extension are based on close coordination between KfK and the GNS mbH, in order to put structural dimensioning and capacity planning on a realistic basis in line with expected amounts of radwaste from operating nuclear installations of utilities. The paper indicates the currently available waste amount assessments covering solid radwaste (MAW) from the decommissioning of the WAK, MZFR, and KNK II, and existing waste amounts consisting of core internals of German nuclear power plant. The figures show that the MAW scrap processing facility will have to process an overall bulk of about 1100 Mg of solid waste over the next ten years to come. (orig./HP) [de

MRS transfer facility feasibility study

International Nuclear Information System (INIS)

Jowdy, A.K.; Smith, R.I.

1990-12-01

Under contract to the US Department of Energy, Parsons was requested to evaluate the feasibility of building a simple hot cell (waste handling) transfer facility at the Monitored Retrievable Storage (MRS) site to facilitate acceptance of spent fuel into the Federal Waste Management System starting in early 1998. The Transfer Facility was intended to provide a receiving and transfer to storage capability at a relatively low throughput rate (approximately 500 MTU/yr) and to provide the recovery capability needed on the site in the event of a transport or storage cask seal failure during a period of about two years while the larger Spent Fuel Handling Building (SFHB) was being completed. Although the original study basis postulated an incremental addition to the larger, previously considered MRS configurations, study results show that the Transfer Facility may be capable of receiving and storing spent fuel at annual rates of 3000 MTU/yr or more, making a larger fuel handling structure unnecessary. In addition, the study analyses showed that the Transfer Facility could be constructed and put into service in 15--17 months and would cost less than the previous configurations. 2 figs., 2 tabs

324 Facility B-cell quality process plan

International Nuclear Information System (INIS)

Carlson, J.L.

1998-01-01

B-Cell is currently being cleaned out (i.e., removal of equipment, fixtures and residual radioactive materials) and deactivated. TPA Milestone M-89-02 dictates that all mixed waste and equipment be removed from B-Cell by 5/31/99. The following sections describe the major activities that remain for completion of the TPA milestone. These include: Size Reduce Tank 119 and Miscellaneous Equipment; Load and Ship Low-Level Waste; Remove and Size Reduce the 1B Rack; Collect Dispersible Material from Cell Floor; Remove and Size Reduce the 2A Rack; Size Reduce the 1A Rack; Load and Ship Mixed Waste to PUREX Tunnels; and Move Spent Fuel to A-Cell;

Outline of the Chemical Processing Facility (CPF)

International Nuclear Information System (INIS)

Arita, Katsuhiko

1978-01-01

Concerning the Chemical Processing Facility (CPF), a high level radioactive material research facility, to be installed in Tokai Works of Power Reactor and Nuclear Fuel Development Corporation (PNC), the detailed design and the governmental safety inspection were finished. The construction has been already started, and it will be completed in 1980. Under the national policy of establishing a nuclear fuel cycle, PNC is now carrying out the development of its downstream technology. The objects of the Chemical Processing Facility are the researches of the treatment techniques of high level radioactive liquid wastes from fuel reprocessing and of the reprocessing of fast reactor fuel. The following matters are described: purpose of the CPF, i.e. fast reactor fuel reprocessing and high-level liquid waste treatment; construction of the CPF, i.e. buildings, cells and an exhaust stack; test systems, i.e. fuel reprocessing and liquid waste vitrification; and facility safety. (Mori, K.)

Defense Waste Processing Facility Nitric- Glycolic Flowsheet Chemical Process Cell Chemistry: Part 2

Energy Technology Data Exchange (ETDEWEB)

Zamecnik, J. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Edwards, T. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

2017-06-06

The conversions of nitrite to nitrate, the destruction of glycolate, and the conversion of glycolate to formate and oxalate were modeled for the Nitric-Glycolic flowsheet using data from Chemical Process Cell (CPC) simulant runs conducted by Savannah River National Laboratory (SRNL) from 2011 to 2016. The goal of this work was to develop empirical correlation models to predict these values from measureable variables from the chemical process so that these quantities could be predicted a-priori from the sludge or simulant composition and measurable processing variables. The need for these predictions arises from the need to predict the REDuction/OXidation (REDOX) state of the glass from the Defense Waste Processing Facility (DWPF) melter. This report summarizes the work on these correlations based on the aforementioned data. Previous work on these correlations was documented in a technical report covering data from 2011-2015. This current report supersedes this previous report. Further refinement of the models as additional data are collected is recommended.

The operation of post-irradiation examination facility

Energy Technology Data Exchange (ETDEWEB)

Kim, Eun Ka; Park, Kwang Jun; Lee, Won Sang [and others; Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

1994-01-01

The operation and management of PIE facility was executed in 1993. An indigenous 16 x 16 PWR type fuel assembly (ID No. J44) which was discharged from Kori unit 2 power reactor was transported to KAERI`s PIE facility and in-pool nondestructive examination and hot cell examination for the fuel were carried out. Because the above-mentioned 16 x 16 fuel is different from 14 x 14 fuel in its size and array of fuel rods, several examination and handling equipment for the 16 x 16 type fuel were designed and fabricated. PIE facility was operated in normal condition with the periodical check and inspection of the devices. The filter housing on the roof hood in chemical analysis hot cell was modified mounting air pressure gauge to indicate the optimal filter exchanging time. The burst air heating coil plate and the broken blowing fan of the HVAC system were repaired. The defaced grand packing in pool water circulation pump was replaced with the mechanical seal to prevent the leakage from the pump shaft sealing. The radiation monitoring in the facility was carried out to maintain the safe working condition and several radiation monitors were repaired. Spare parts for the radiation monitoring system were prepared to maintain the facility safely. The performance test of the emergency electric power supply system including UPS, battery and diesel generator was carried out. Oxide layer thickness measuring device for the performance test. Several devices including spent fuel handling equipment for the 17 x 17 PWR type fuel assembly were designed and fabricated for the subsequent PIE of nuclear fuels. 35 tabs., 17 figs., 7 refs. (Author) .new.

Gas separation techniques in nuclear facilities

International Nuclear Information System (INIS)

Hioki, Hideaki; Morisue, Tetsuo; Ohno, Masayoshi

1983-01-01

The literatures concerning the gas separation techniques which are applied to the waste gases generated from nuclear power plants and nuclear fuel reprocessing plants, uranium enrichment and the instrumentation of nuclear facilities are reviewed. The gas permeability and gas separation performance of membranes are discussed in terms of rare gas separation. The investigation into the change of the gas permeability and mechanical properties of membranes with exposure to radiation is reported. The theoretical investigation of the separating cells used for the separation of rare gas and the development of various separating cells are described, and the theoretical and experimental investigations concerning rare gas separation using cascades are described. The application of membrane method to nuclear facilities is explained showing the examples of uranium enrichment, the treatment of waste gases from nuclear reactor buildings and nuclear fuel reprocessing plants, the monitoring of low level β-emitters in stacks, the detection of failed fuels and the detection of water leak in fast breeder reactors. (Yoshitake, I.)

Performance assessment of the proposed Monitored Retrievable Storage Facility

International Nuclear Information System (INIS)

Chockie, A.D.; Hostick, C.J.; Winter, C.

1986-02-01

Pacific Northwest laboratory (PNL) has completed a performance evaluation of the proposed monitored retrievable storage (MRS) facility. This study was undertaken as part of the Department of Energy MRS Program at PNL. The objective of the performance evaluation was to determine whether the conceptual MRS facility would be able to process spent fuel at the specified design rate of 3600 metric tons of uranium (MTU) per year. The performance of the proposed facility was assessed using the computer model COMPACT (Computer Optimization of Processing and Cask Transport) to simulate facility operations. The COMPACT model consisted of three application models each of which addressed a different aspect of the facility's operation: MRS/waste transportation interface; cask handling capability; and disassembly/consolidation (hot cell) operations. Our conclusions, based on the assessment of design criteria for the proposed facility, are as follows: Facilities and equipment throughout the facility have capability beyond the 3600 MTU/y design requirement. This added capability provides a reserve to compensate for unexpected perturbations in shipping or handling of the spent fuel. Calculations indicate that the facility's maximum maintainable processing capability is approximately 4800 MTU/y

Facile template-free hydrothermal synthesis and microstrain ...

Indian Academy of Sciences (India)

Administrator

2009), solar cells (Yuan et al 2011), transparent elec- trodes (Kim et al ... increasing the peak width, intensity and shifting the 2θ peak position. ... Facile template-free hydrothermal synthesis and microstrain measurement of ZnO nanorods. 399.

SNS Target Test Facility for remote handling design and verification

International Nuclear Information System (INIS)

Spampinato, P.T.; Graves, V.B.; Schrock, S.L.

1998-01-01

The Target Test Facility will be a full-scale prototype of the Spallation Neutron Source Target Station. It will be used to demonstrate remote handling operations on various components of the mercury flow loop and for thermal/hydraulic testing. This paper describes the remote handling aspects of the Target Test Facility. Since the facility will contain approximately 1 cubic meter of mercury for the thermal/hydraulic tests, an enclosure will also be constructed that matches the actual Target Test Cell

Column study on electrochemical separation of cesium ions from wastewater using copper hexacyanoferrate film

International Nuclear Information System (INIS)

Chen, Rongzhi; Tanaka, Hisashi; Asai, Miyuki; Fukushima, Chikako; Kawamoto, Tohru; Kurihara, Masato; Ishizaki, Manabu; Arisaka, Makoto; Nankawa, Takuya; Watanabe, Masayuki

2013-01-01

We coated the copper hexacyanoferrate (CuHCF) on the gold electrodes, and then performed the Cs removal by electrochemical separation (ES). The prepared CuHCF nanoparticles can be simply and uniformly coated on electrodes by wet process like conventional printing methods, so any sizes or patterns are feasible at low cost, which indicated the potential as a promising sorption electrode of large size in the columns for sequential removal and recycle of Cs from wastewater. (author)

The Use of Wetting Agents/Fume Supressants for Minimizing the Atmospheric Emissions from Hard Chromium Electroplating Baths

Science.gov (United States)

2003-08-01

Accreditation (A2LA) for compliance with ISO 9001, Quality Systems - Model for Quality Assurance in Design, Development, Production, Installation and Servicing...All samples handling and testing at Patuxent River laboratory is ISO 9001 compliant. Appendix D, Table 1, 2, and 4 outline the test methods...HCF 0.1 4 3 8583 ± 288 8257/8909 8155/9012 1 TEST (N = 44090 CYCLES) TREATED AS AN OUTLIER. EXTRA HARD CHROME WITH FUME SUPPRESSANT HCF -1 4 4

Universal Test Facility

Science.gov (United States)

Laughery, Mike

A universal test facility (UTF) for Space Station Freedom is developed. In this context, universal means that the experimental rack design must be: automated, highly marketable, and able to perform diverse microgravity experiments according to NASA space station requirements. In order to fulfill these broad objectives, the facility's customers, and their respective requirements, are first defined. From these definitions, specific design goals and the scope of the first phase of this project are determined. An examination is first made into what types of research are most likely to make the UTF marketable. Based on our findings, the experiments for which the UTF would most likely be used included: protein crystal growth, hydroponics food growth, gas combustion, gallium arsenide crystal growth, microorganism development, and cell encapsulation. Therefore, the UTF is designed to fulfill all of the major requirements for the experiments listed above. The versatility of the design is achieved by taking advantage of the many overlapping requirements presented by these experiments.

A clinical prediction rule for histological chorioamnionitis in preterm newborns.

Directory of Open Access Journals (Sweden)

Jasper V Been

Full Text Available BACKGROUND: Histological chorioamnionitis (HC is an intrauterine inflammatory process highly associated with preterm birth and adverse neonatal outcome. HC is often clinically silent and diagnosed postnatally by placental histology. Earlier identification could facilitate treatment individualisation to improve outcome in preterm newborns. AIM: Develop a clinical prediction rule at birth for HC and HC with fetal involvement (HCF in preterm newborns. METHODS: Clinical data and placental pathology were obtained from singleton preterm newborns (gestational age ≤ 32.0 weeks born at Erasmus UMC Rotterdam from 2001 to 2003 (derivation cohort; n = 216 or Máxima MC Veldhoven from 2009 to 2010 (validation cohort; n = 206. HC and HCF prediction rules were developed with preference for high sensitivity using clinical variables available at birth. RESULTS: HC and HCF were present in 39% and 24% in the derivation cohort and in 44% and 22% in the validation cohort, respectively. HC was predicted with 87% accuracy, yielding an area under ROC curve of 0.95 (95%CI = 0.92-0.98, a positive predictive value of 80% (95%CI = 74-84%, and a negative predictive value of 93% (95%CI = 88-96%. Corresponding figures for HCF were: accuracy 83%, area under ROC curve 0.92 (95%CI = 0.88-0.96, positive predictive value 59% (95%CI = 52-62%, and negative predictive value 97% (95%CI = 93-99%. External validation expectedly resulted in some loss of test performance, preferentially affecting positive predictive rather than negative predictive values. CONCLUSION: Using a clinical prediction rule composed of clinical variables available at birth, HC and HCF could be predicted with good test characteristics in preterm newborns. Further studies should evaluate the clinical value of these rules to guide early treatment individualisation.

Electrocatalytic behaviour of hybrid cobalt–manganese hexacyanoferrate film on glassy carbon electrode

International Nuclear Information System (INIS)

Vinu Mohan, A.M.; Rambabu, Gutru; Aswini, K.K.; Biju, V.M.

2014-01-01

A thin film of hybrid cobalt–manganese hexacyanoferrate (CoMnHCF), a redox mediator was electrodeposited on a glassy carbon (GC) electrode and was employed as an amperometric sensor towards L-Tryptophan (L-Trp). The hybrid film was characterized by Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction technique (XRD), scanning electron microscope–energy dispersive X-ray spectroscopy (SEM–EDAX), and electrochemical techniques. The atomic absorption spectroscopic analysis provided the stoichiometry of the hybrid film to be K 1.74-y Co y Mn 0.78 [Fe(CN) 6 ], y ≤ 0.68. The electrochemical impedance study revealed the excellent charge transfer properties of GC/CoMnHCF electrode. The voltammetric investigations demonstrated exceptional electrocatalytic properties of the hybrid film modified electrode when compared to that of bare GC, GC/CoHCF and GC/MnHCF electrodes, towards the L-Trp oxidation. The kinetic parameters such as electron transfer coefficient, the electron transfer rate constant, the diffusion coefficient and the catalytic rate constant for the electrooxidation process of L-Trp were investigated. The amperometric detection of L-Trp employing GC/CoMnHCF electrode possessed a good sensitivity of 10 × 10 −2 A M −1 cm −2 in a wide range of detection (2–200 μM) at a reduced overpotential of 680 mV. In addition, the proposed amperometric method was applied to the detection of L-Trp in commercial milk samples with reproducible results. - Highlights: • A hybrid cobalt–manganese hexacyanoferrate film was prepared. • The hybrid film possesses excellent charge transfer properties. • The hybrid film exhibits excellent electrocatalytic properties towards Tryptophan. • Tryptophan detection is possible from commercial milk samples

Electrochemical Removal of Radioactive Cesium from Nuclear Waste Using the Dendritic Copper Hexacyanoferrate/Carbon Nanotube Hybrids

International Nuclear Information System (INIS)

Zheng, Yuanyuan; Qiao, Junhua; Yuan, Junhua; Shen, Jianfeng; Wang, Ai-jun; Niu, Li

2017-01-01

Highlights: •Copper hexacyanoferrate was uniformly covered on carbon nanotubes. •Cs + ion can be exchanged using this hybrid by controlling the electrode potential. •The maximum of Cs + adsorption capacity is 310 mg·g −1 in 50 μM Cs + solution. •The distribution coefficient of Cs + in this hybrid reaches up to 568 L·g −1 ,. •This hybrid can be regenerated with high stability for Cs + exchange. -- Abstract: A novel electrochemical separation system was developed based on copper hexacyanoferrate/multiwalled carbon nanotube (CuHCF/MWCNT) hybrids for selectively removing cesium from wastewater. These CuHCF/MWCNT hybrids were prepared by co-precipitation strategy. The as-prepared CuHCF nanoparticles were uniformly covered on MWCNTs to form a dendritic core-shell structure. This novel structure can improve CuHCFs conductivity, making CuHCFs more accessible for ion exchange. The uptake and release of alkali ion in CuHCF/MWCNT hybrids can be shifted mutually by switching the applied potentials between the anode and cathode. This ion exchange is a fast and reversible process associated with electron transfer in CuHCFs. The potential response depends on the radius of alkali ion. Using this electrochemical adsorption system (EAS), the maximum adsorption capacity (Q max ) of Cs + ion for CuHCFs/MWCNT hybrids reaches up to 310 mg·g −1 in 50 μM Cs + solution with a distribution coefficient K d of 568 L·g −1 , superior to the Cs + removal performance by the conventional adsorption system (Q max 230 mg·g −1 , Kd 389 L·g −1 ). Besides, CuHCF/MWCNT hybrids can be regenerated electrochemically. In addition to the advantages in Cs + removal performance and electrochemical regenerability, they can maintain considerable stability with uptake capacity retention of 85% after 100 cycles of adsorption and regeneration.

Leptin is associated with exaggerated brain reward and emotion responses to food images in adolescent obesity.

Science.gov (United States)

Jastreboff, Ania M; Lacadie, Cheryl; Seo, Dongju; Kubat, Jessica; Van Name, Michelle A; Giannini, Cosimo; Savoye, Mary; Constable, R Todd; Sherwin, Robert S; Caprio, Sonia; Sinha, Rajita

2014-11-01

In the U.S., an astonishing 12.5 million children and adolescents are now obese, predisposing 17% of our nation's youth to metabolic complications of obesity, such as type 2 diabetes (T2D). Adolescent obesity has tripled over the last three decades in the setting of food advertising directed at children. Obese adults exhibit increased brain responses to food images in motivation-reward pathways. These neural alterations may be attributed to obesity-related metabolic changes, which promote food craving and high-calorie food (HCF) consumption. It is not known whether these metabolic changes affect neural responses in the adolescent brain during a crucial period for establishing healthy eating behaviors. Twenty-five obese (BMI 34.4 kg/m2, age 15.7 years) and fifteen lean (BMI 20.96 kg/m2, age 15.5 years) adolescents underwent functional MRI during exposure to HCF, low-calorie food (LCF), and nonfood (NF) visual stimuli 2 h after isocaloric meal consumption. Brain responses to HCF relative to NF cues increased in obese versus lean adolescents in striatal-limbic regions (i.e., putamen/caudate, insula, amygdala) (P < 0.05, family-wise error [FWE]), involved in motivation-reward and emotion processing. Higher endogenous leptin levels correlated with increased neural activation to HCF images in all subjects (P < 0.05, FWE). This significant association between higher circulating leptin and hyperresponsiveness of brain motivation-reward regions to HCF images suggests that dysfunctional leptin signaling may contribute to the risk of overconsumption of these foods, thus further predisposing adolescents to the development of obesity and T2D. © 2014 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered.

An improved out-cell to in-cell rapid transfer system at the HFEF/South

International Nuclear Information System (INIS)

Bacca, J.P.; Sherman, E.K.

1991-01-01

This paper reports on Argonne National Laboratory's Fuel Cycle Facility (FCF) (formerly named Hot Fuel Examination Facility-South) (HFEF/South) which is currently being refurbished and upgraded in preparation for demonstrating remote, fast reactor metal-fuel reprocessing and refabrication, as part of the Integral Fast Reactor (IFR) Program. Among the FCF hot-cell system upgrades being provided is a newly fabricated, direct, out-of-cell to in-cell, small-item transfer system for the FCF argon cell. This system will enable the rapid transfer of selected small items from the hot cell exterior into the argon cell (argon-gas atmosphere) of the facility, without necessitating the use of formerly employed, very time-consuming, and quite laborious procedures. The new system will be especially valuable for the rapid insertion of IFR fuel processing makeup materials and small tools into the argon cell, and for use in argon cell and overall FCF radioactive contamination-control activities

Facilities for post-irradiation examination of experimental fuel elements at Chalk River Nuclear Laboratories

International Nuclear Information System (INIS)

Mizzan, E.; Chenier, R.J.

1979-10-01

Expansion of post-irradiation facilities at the Chalk River Nuclear Laboratories and steady improvement in hot-cell techniques and equipment are providing more support to Canada's reactor fuel development program. The hot-cell facility primarily used for examination of experimental fuels averages a quarterly throughput of 40 elements and 110 metallographic specimens. New developments in ultrasonic testing, metallographic sample preparation, active storage, active waste filtration, and fissile accountability are coming into use to increase the efficiency and safety of hot-cell operations. (author)

Preconceptual design for a Monitored Retrievable Storage (MRS) transfer facility

International Nuclear Information System (INIS)

Woods, W.D.; Jowdy, A.K.; Smith, R.I.

1990-09-01

The contract between the DOE and the utilities specifies that the DOE will receive spent fuel from the nuclear utilities in 1998. This study investigates the feasibility of employing a simple Transfer Facility which can be constructed quickly, and operate while the full-scale MRS facilities are being constructed. The Transfer Facility is a hot cell designed only for the purpose of transferring spent fuel assemblies from the Office of Civilian Radioactive Waste Management (OCRWM) transport casks (shipped from the utility sites) into onsite concrete storage casks. No operational functions other than spent fuel assembly transfers and the associated cask handling, opening, and closing would be performed in this facility. Radioactive waste collected in the Transfer Facility during operations would be stored until the treatment facilities in the full-scale MRS facility became operational, approximately 2 years after the Transfer Facility started operation. An alternate wherein the Transfer Facility was the only waste handling building on the MRS site was also examined and evaluated. 6 figs., 26 tabs

Implementing partnerships in nonreactor facility safety analyses

International Nuclear Information System (INIS)

Courtney, J.C.; Perry, W.H.; Phipps, R.D.

1996-01-01

Faculty and students from LSU have been participating in nuclear safety analyses and radiation protection projects at ANL-W at INEL since 1973. A mutually beneficial relationship has evolved that has resulted in generation of safety-related studies acceptable to Argonne and DOE, NRC, and state regulatory groups. Most of the safety projects have involved the Hot Fuel Examination Facility or the Fuel Conditioning Facility; both are hot cells that receive spent fuel from EBR-II. A table shows some of the major projects at ANL-W that involved LSU students and faculty

Sub-scale Direct Connect Supersonic Combustion Facility (Research Cell 18)

Data.gov (United States)

Federal Laboratory Consortium — Description: RC18 is a continuous-flow, direct-connect, supersonic-combustion research facility that is capable of simulating flight conditions from Mach 3.0 to Mach...

Emission Facilities - Erosion & Sediment Control Facilities

Data.gov (United States)

NSGIC Education | GIS Inventory — An Erosion and Sediment Control Facility is a DEP primary facility type related to the Water Pollution Control program. The following sub-facility types related to...

Status of the low-energy super-heavy element facility at RIKEN

Energy Technology Data Exchange (ETDEWEB)

Schury, P., E-mail: schury@riken.jp [RIKEN, Nishina Center for Accelerator Based Science, Wako City, Saitama (Japan); Wada, M.; Ito, Y. [RIKEN, Nishina Center for Accelerator Based Science, Wako City, Saitama (Japan); Arai, F. [RIKEN, Nishina Center for Accelerator Based Science, Wako City, Saitama (Japan); Institute of Physics, University of Tsukuba, Tsukuba City, Ibaraki (Japan); Kaji, D. [RIKEN, Nishina Center for Accelerator Based Science, Wako City, Saitama (Japan); Kimura, S. [Institute of Physics, University of Tsukuba, Tsukuba City, Ibaraki (Japan); Morimoto, K.; Haba, H. [RIKEN, Nishina Center for Accelerator Based Science, Wako City, Saitama (Japan); Jeong, S. [Institute of Particle and Nuclear Studies (IPNS), High Energy Accelerator Research Organization (KEK), Ibaraki 305-0801 (Japan); Koura, H. [Advanced Science Research Center, Japan Atomic Energy Agency, Ibaraki 319-1195 (Japan); Miyatake, H. [Institute of Particle and Nuclear Studies (IPNS), High Energy Accelerator Research Organization (KEK), Ibaraki 305-0801 (Japan); Morita, K.; Reponen, M. [RIKEN, Nishina Center for Accelerator Based Science, Wako City, Saitama (Japan); Ozawa, A. [Institute of Physics, University of Tsukuba, Tsukuba City, Ibaraki (Japan); Sonoda, T.; Takamine, A. [RIKEN, Nishina Center for Accelerator Based Science, Wako City, Saitama (Japan); Wollnik, H. [Dept. Chemistry and BioChemistry, New Mexico State University, Las Cruces, NM (United States)

2016-06-01

In order to investigate nuclei produced via fusion–evaporation reactions, especially super-heavy elements (SHE), we have begun construction of a facility for conversion of fusion–evaporation residues (EVR) to low-energy beams. At the base of this facility is a small cryogenic gas cell utilizing a traveling wave RF-carpet, located directly following the gas-filled recoil ion separator GARIS-II, which will thermalize EVRs to convert them into ion beams amenable to ion trapping. We present here the results of initial studies of this small gas cell.

Facile Conversion Synthesis of Densely-Formed Branched ZnO-Nanowire Arrays for Quantum-Dot-Sensitized Solar Cells

International Nuclear Information System (INIS)

Lee, Woojin; Kang, Suji; Hwang, Taehyun; Kim, Kunsu; Woo, Hyungsub; Lee, Byungho; Kim, Jaewon; Kim, Jinhyun; Park, Byungwoo

2015-01-01

Highlights: •3-D hierarchically branched ZnO nanowires by a facile synthesis with seed nucleation. •Nanobranching enhances the efficiency by a factor of two compared with the bare QDSC. •Attributed to the increased sensitizer by ∼80% and decreased transmittance by ∼17%. •Optimized nanostructures correlate with the light-harvesting and carrier-collection efficiencies. -- Abstract: An effective way of synthesizing densely-formed branched ZnO-nanowire arrays was developed by a straightforward conversion reaction of ZnS into ZnO. Hierarchically structured ZnO nanowires are utilized for quantum-dot-sensitized solar cells (QDSCs), having resulted in the conversion-efficiency enhancement by a factor of two compared to the bare ZnO nanowires. This is attributed to the increased CdS-quantum-dot sensitizer by ∼80% and decreased diffused transmittance by ∼17%, induced by the densely-formed branched nanowires. The correlations between the branched nanostructures and photovoltaic performances are systematically investigated in terms of light absorption, charge-transfer resistance, and carrier lifetime. This facile and controllable branched nanowire synthesis is anticipated to be applicable to other semiconductor photoanodes for efficient light harvesting and charge collecting properties

Hydrogen Infrastructure Testing and Research Facility Video (Text Version)

Science.gov (United States)

grid integration, continuous code improvement, fuel cell vehicle operation, and renewable hydrogen Systems Integration Facility or ESIF. Research projects including H2FIRST, component testing, hydrogen

Buying food on sale: a mixed methods study with shoppers at an urban supermarket, Philadelphia, Pennsylvania, 2010-2012.

Science.gov (United States)

Phipps, Etienne J; Kumanyika, Shiriki K; Stites, Shana D; Singletary, S Brook; Cooblall, Clarissa; DiSantis, Katherine Isselmann

2014-09-04

The obesity epidemic has drawn attention to food marketing practices that may increase the likelihood of caloric overconsumption and weight gain. We explored the associations of discounted prices on supermarket purchases of selected high-calorie foods (HCF) and more healthful, low-calorie foods (LCF) by a demographic group at high risk of obesity. Our mixed methods design used electronic supermarket purchase data from 82 low-income (primarily African American female) shoppers for households with children and qualitative data from focus groups with demographically similar shoppers. In analyses of 6,493 food purchase transactions over 65 weeks, the odds of buying foods on sale versus at full price were higher for grain-based snacks, sweet snacks, and sugar-sweetened beverages (odds ratios: 6.6, 5.9, and 2.6, respectively; all P snacks. The odds of buying foods on sale versus full price were not higher for any of any of the LCF (P ≥ .07). Without controlling for quantities purchased, we found that spending increased as percentage saved from the full price increased for all HCF and for fruits and vegetables (P ≤ .002). Focus group participants emphasized the lure of sale items and took advantage of sales to stock up. Strategies that shift supermarket sales promotions from price reductions for HCF to price reductions for LCF might help prevent obesity by decreasing purchases of HCF.

Microstructure characteristics and temperature-dependent high cycle fatigue behavior of advanced 9% Cr/CrMoV dissimilarly welded joint

International Nuclear Information System (INIS)

Wu, Qingjun; Lu, Fenggui; Cui, Haichao; Ding, Yuming; Liu, Xia; Gao, Yulai

2014-01-01

Advanced 9% Cr and CrMoV steels chosen as candidate materials are first welded by narrow-gap submerged arc welding (NG-SAW) to fabricate the heavy section rotor. The present work focuses on studying the high-cycle fatigue (HCF) behavior of advanced 9% Cr/CrMoV dissimilarly welded joint at different temperatures. Conditional fatigue strength of this dissimilarly welded joint was obtained by HCF tests at room temperature (RT), 400 °C and 470 °C. It was observed that the failure occurred at the side of CrMoV base metal (BM), weld metal (WM) and heat affected zone (HAZ) of CrMoV side over 5×10 7 cycles for the specimens tested at RT, 400 °C and 470 °C. The detailed microstructures of BMs, WMs and HAZs as well as fracture appearance were observed by optical microscopy (OM) and scanning electron microscopy (SEM). Precipitation and aggregation of carbides along the grain boundaries were clearly detected with the increase of temperature, which brought a negative effect on the fatigue properties. It is interesting to note that the inclusion size leading to crack initiation became smaller for the HCF test at higher temperature. Therefore, reduction in the inclusion size in a welded joint helps to improve the HCF performance at high temperature

Microstructure characteristics and temperature-dependent high cycle fatigue behavior of advanced 9% Cr/CrMoV dissimilarly welded joint

Energy Technology Data Exchange (ETDEWEB)

Wu, Qingjun [Shanghai Key Laboratory of Materials Laser Processing and Modification, Shanghai Jiao Tong University, Shanghai 200240 (China); Lu, Fenggui, E-mail: Lfg119@sjtu.edu.cn [Shanghai Key Laboratory of Materials Laser Processing and Modification, Shanghai Jiao Tong University, Shanghai 200240 (China); Shanghai Key Laboratory of Modern Metallurgy and Materials Processing, Shanghai University, Shanghai 200072 (China); Cui, Haichao [Shanghai Key Laboratory of Materials Laser Processing and Modification, Shanghai Jiao Tong University, Shanghai 200240 (China); Ding, Yuming; Liu, Xia [Shanghai Turbine Plant of Shanghai Electric Power Generation Equipment Co. Ltd., Shanghai 200240 (China); Gao, Yulai, E-mail: ylgao@shu.edu.cn [Shanghai Key Laboratory of Modern Metallurgy and Materials Processing, Shanghai University, Shanghai 200072 (China)

2014-10-06

Advanced 9% Cr and CrMoV steels chosen as candidate materials are first welded by narrow-gap submerged arc welding (NG-SAW) to fabricate the heavy section rotor. The present work focuses on studying the high-cycle fatigue (HCF) behavior of advanced 9% Cr/CrMoV dissimilarly welded joint at different temperatures. Conditional fatigue strength of this dissimilarly welded joint was obtained by HCF tests at room temperature (RT), 400 °C and 470 °C. It was observed that the failure occurred at the side of CrMoV base metal (BM), weld metal (WM) and heat affected zone (HAZ) of CrMoV side over 5×10{sup 7} cycles for the specimens tested at RT, 400 °C and 470 °C. The detailed microstructures of BMs, WMs and HAZs as well as fracture appearance were observed by optical microscopy (OM) and scanning electron microscopy (SEM). Precipitation and aggregation of carbides along the grain boundaries were clearly detected with the increase of temperature, which brought a negative effect on the fatigue properties. It is interesting to note that the inclusion size leading to crack initiation became smaller for the HCF test at higher temperature. Therefore, reduction in the inclusion size in a welded joint helps to improve the HCF performance at high temperature.

Modal characteristics and fatigue strength of compressor blades

International Nuclear Information System (INIS)

Kim, Kyung Kook; Lee, Young Shin

2014-01-01

High-cycle fatigue (HCF) has been identified as one of the primary causes of gas turbine engine failure. The modal characteristics and endurance strength of a 5 MW gas turbine engine blade developed by Doosan Heavy Industries and Construction Co., Ltd. in HCF fracture were verified through analysis and tests to determine the reliability of the compressor blade. A compressor blade design procedure that considers HCF life was performed in the following order: airfoil and blade profile design, modal analysis, stress distribution test, stress endurance limit test, and fatigue life verification. This study analyzed the Campbell diagram and estimated resonance risk on the basis of the natural frequency analysis and modal test of the compressor blade to guarantee safe and operational reliability. In addition, the maximum stress point of the compressor blade was determined through stress distribution analysis and test. The bonding point of the strain gage was determined by using fatigue test. Stress endurance limit test was performed based on the results of these tests. This research compared and verified the modal characteristics and endurance strengths of the compressor blades to prevent HCF fracture, which is among the major causes of gas turbine engine damage. A fatigue life design procedure of compressor blades was established. The 5 MW class gas turbine compressor blade is well designed in terms of resonance stability and fatigue endurance limit.

Modal characteristics and fatigue strength of compressor blades

Energy Technology Data Exchange (ETDEWEB)

Kim, Kyung Kook [Doosan Heavy Industries and Construction, Changwon (Korea, Republic of); Lee, Young Shin [Chungnam National University, Daejeon (Korea, Republic of)

2014-04-15

High-cycle fatigue (HCF) has been identified as one of the primary causes of gas turbine engine failure. The modal characteristics and endurance strength of a 5 MW gas turbine engine blade developed by Doosan Heavy Industries and Construction Co., Ltd. in HCF fracture were verified through analysis and tests to determine the reliability of the compressor blade. A compressor blade design procedure that considers HCF life was performed in the following order: airfoil and blade profile design, modal analysis, stress distribution test, stress endurance limit test, and fatigue life verification. This study analyzed the Campbell diagram and estimated resonance risk on the basis of the natural frequency analysis and modal test of the compressor blade to guarantee safe and operational reliability. In addition, the maximum stress point of the compressor blade was determined through stress distribution analysis and test. The bonding point of the strain gage was determined by using fatigue test. Stress endurance limit test was performed based on the results of these tests. This research compared and verified the modal characteristics and endurance strengths of the compressor blades to prevent HCF fracture, which is among the major causes of gas turbine engine damage. A fatigue life design procedure of compressor blades was established. The 5 MW class gas turbine compressor blade is well designed in terms of resonance stability and fatigue endurance limit.

Operation of post-irradiation examination facility

Energy Technology Data Exchange (ETDEWEB)

Kim, Eun Ka; Park, Kwang Joon; Jeon, Yong Bum [and others; Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

1995-02-01

In 1995, the post-irradiation examination (PIE) of nuclear fuels was performed as follows. The relation between burnup and top nozzle spring force of fuel assembly was obtained by measuring the holddown spring force on the Kori-1 reactor fuel assemblies. The resonance ultrasonic test for inspection of defect and moisture in fuel rod was carried out on fuel rods of C15 and J14 assemblies, and the change of fuel rod condition by storing in pool has been analyzed on the intentionally defected fuel rods (ID-C and ID-L) as well as intact fuel rod (1-2) by NDT in ht cell. The oxide layer thickness on cladding surface of J44-L12 fuel rod was measured by NDT method and metallography to reveal the oxidation as a function of temperature in the fuel rod, and the burnup of J44 fuel assembly was measured by chemical analysis. HVAC system and pool water treatment system of the PIE facility were continuously operated for air filtration and water purification. The monitoring of radiation and pool water in PIE facility has been carried out to maintain the facility safety, and electric power supply system was checked and maintained to supply the electric power to the facility normally. The developed measurement techniques of oxide layer thickness on fuel rod cladding and holddown spring force of top nozzle in fuel assembly were applied to examine the nuclear fuels. Besides, a radiation shielding glove box was designed and a hot cell compressor for volume reduction of radioactive materials was fabricated. 19 tabs., 38 figs., 7 refs. (Author) .new.

Criticality safety training at the Hot Fuel Examination Facility

International Nuclear Information System (INIS)

Garcia, A.S.; Courtney, J.C.; Thelen, V.N.

1983-01-01

HFEF comprises four hot cells and out-of-cell support facilities for the US breeder program. The HFEF criticality safety program includes training in the basic theory of criticality and in specific criticality hazard control rules that apply to HFEF. A professional staff-member oversees the implementation of the criticality prevention program

Microbeam facility extension for single-cell irradiation experiments. Investigations about bystander effect and reactive oxygen species impact

International Nuclear Information System (INIS)

Hanot, M.; Khodja, H.; Daudin, L.; Hoarau, J.; Carriere, M.; Gouget, B.

2006-01-01

The LPS microbeam facility is based on a KN3750 Van de Graaff accelerator devoted to microbeam analysis [1]. It is equipped with two horizontal microbeam lines used in various fields such as material science, geological science, nuclear material science and biology. Since two years, a single ion hit device is being developed at the LPS. The setup is dedicated to the study of ionizing radiation effects on living cells by performing single ion irradiation at controlled doses and locations. This study will complete current researches conducted on uranium chemical toxicity on renal an d osteoblastic cells. After ingestion, most uranium is excreted from the body within a few days except small fraction that is absorbed into the blood-stream (0.2 to 5%) and then deposit and preferentially in kidneys and bones, where it can remain for many years. Uranium is a heavy metal and a primarily alpha emitter. It can lead to bone cancer as a result of the ionizing radiation associated with the radioactive decay products. The study of the response to an exposure to alpha particles will permit to distinguish radiotoxicity and chemical toxicity of uranium bone cells with a special emphasis or the bystander effect at low dose.All the beam lines at the LPS nuclear microprobe are horizontal and under vacuum. A dedicated deflecting magnet was inserted in one of the two available beam lines of the facility. The ion beam is extracted to air using a 100 nm thick silicon nitride membrane, thin enough to induce negligible effects on the ions in terms of energy loss and spatial resolution. By this way, we believe that we minimize the experimental setup impact on the living cells easing the detection of low irradiation dose impact. The atmosphere around the samples is also important to guaranty low stressed cell culture conditions. A temperature, hygrometry and CO 2 controlled atmosphere device will be implanted in the future. The irradiation microbeam is produced using a fused silica capillary

Alternative cask maintenance facility concepts

International Nuclear Information System (INIS)

Attaway, C.R.; Pope, R.B.; Wiliamson, A.C.; Medley, L.G.; Shappert, L.B.

1992-01-01

In this paper, the results of three trade-off studies of alternative concepts for performing cask maintenance for Civilian Radioactive Waste Management System casks are presented. An earlier study resulted in a recommendation that a submerged pool concept for cask internal component removal be used in the design of a Cask Maintenance Facility. The first trade-off study resulted in confirming the previous recommendation that a submerged pool concept be used rather than an isolation cell; the basis for this continued recommendation is discussed. The second study provides an evaluation of the previously proposed facility for the capability of handling an increased quantity of OCRWM casks. The third study provides a preliminary concept for adding the capability to repaint the exterior cylindrical portions of casks

Transmittal of the Calculation Package that Supports the Analysis of Performance of the Environmental Management Waste Management Facility Oak Ridge, Tennessee (Based 5-Cell Design Issued 8/14/09)

Energy Technology Data Exchange (ETDEWEB)

Williams M.J.

2009-09-14

This document presents the results of an assessment of the performance of a build-out of the Environmental Management Waste Management Facility (EMWMF). The EMWMF configuration that was assessed includes the as-constructed Cells 1 through 4, with a groundwater underdrain that was installed beneath Cell 3 during the winter of 2003-2004, and Cell 5, whose proposed design is an Addendum to Remedial Design Report for the Disposal of Oak Ridge Reservation Comprehensive Environmental Response, Compensation, and Liability Act of 1980 Waste, Oak Ridge, Tennessee, DOE/OR/01-1873&D2/A5/R1. The total capacity of the EMWMF with 5 cells is about 1.7 million cubic yards. This assessment was conducted to determine the conditions under which the approved Waste Acceptance Criteria (WAC) for the EMWMF found in the Attainment Plan for Risk/Toxicity-Based Waste Acceptance Criteria at the Oak Ridge Reservation, Oak Ridge, Tennessee [U.S. Department of Energy (DOE) 2001a], as revised for constituents added up to October 2008, would remain protective of public health and safety for a five-cell disposal facility. For consistency, the methods of analyses and the exposure scenario used to predict the performance of a five-cell disposal facility were identical to those used in the Remedial Investigation and Feasibility Study (RI/FS) and its addendum (DOE 1998a, DOE 1998b) to develop the approved WAC. To take advantage of new information and design changes departing from the conceptual design, the modeling domain and model calibration were upaded from those used in the RI/FS and its addendum. It should be noted that this analysis is not intended to justify or propose a change in the approved WAC.

Application of advanced remote systems technology to future waste handling facilities

International Nuclear Information System (INIS)

Kring, C.T.; Meacham, S.A.

1987-01-01

The Consolidated Fuel Reprocessing Program (CFRP) at Oak Ridge National Laboratory (ORNL) has been advancing the technology of remote handling and remote maintenance for in-cell systems planned for future nuclear fuel reprocessing plants. Much of the experience and technology developed over the past decade in this endeavor is directly applicable to the proposed in-cell systems being considered for the facilities of the Federal Waste Management System (FWMS). The application of teleoperated, force-reflecting servomanipulators with television viewing could be a major step forward in waste handling facility design. Primary emphasis in the current program is the operation of a prototype remote handling and maintenance system, the advanced servomanipulator (ASM), which specifically addresses the requirements of fuel reprocessing and waste handling with emphasis on force reflection, remote maintainability, reliability, radiation tolerance, and corrosion resistance. Concurrent with the evolution of dexterous manipulators, concepts have also been developed that provide guidance for standardization of the design of the remotely operated and maintained equipment, the interface between the maintenance tools and the equipment, and the interface between the in-cell components and the facility

Ground test facility for nuclear testing of space reactor subsystems

International Nuclear Information System (INIS)

Quapp, W.J.; Watts, K.D.

1985-01-01

Two major reactor facilities at the INEL have been identified as easily adaptable for supporting the nuclear testing of the SP-100 reactor subsystem. They are the Engineering Test Reactor (ETR) and the Loss of Fluid Test Reactor (LOFT). In addition, there are machine shops, analytical laboratories, hot cells, and the supporting services (fire protection, safety, security, medical, waste management, etc.) necessary to conducting a nuclear test program. This paper presents the conceptual approach for modifying these reactor facilities for the ground engineering test facility for the SP-100 nuclear subsystem. 4 figs

Fuel Cell Development and Test Laboratory | Energy Systems Integration

Science.gov (United States)

Facility | NREL Fuel Cell Development and Test Laboratory Fuel Cell Development and Test Laboratory The Energy System Integration Facility's Fuel Cell Development and Test Laboratory supports fuel cell research and development projects through in-situ fuel cell testing. Photo of a researcher running

Notch size effects on high cycle fatigue limit stress of Udimet 720

International Nuclear Information System (INIS)

Ren Weiju; Nicholas, Theodore

2003-01-01

Notch size effects on the high cycle fatigue (HCF) limit stress of Ni-base superalloy Udimet 720 were investigated on cylindrical specimens with three notch sizes of the same stress concentration factor K t =2.74. The HCF limit stress corresponding to a life of 10 6 cycles was experimentally determined at a stress ratio of 0.1 and a frequency of 25 Hz at room temperature. The stresses were calculated using finite element analysis (FEA) and the specimens analyzed using scanning electron microscopy (SEM). Test results show that at the same K t value, notch size can slightly affect the HCF limit stress of U720 when notch root plasticity occurs. FEA and SEM results reveal that the notch size effects are influenced by a complicated combination of the stress and plastic strain fields at the notch tip, the nominal stress, and the effects of prior plastic deformation on fatigue crack initiation

Development of Electrically Switched Ion Exchange Process for Selective Ion Separations

International Nuclear Information System (INIS)

Rassat, Scot D.; Sukamto, Johanes H.; Orth, Rick J.; Lilga, Michael A.; Hallen, Richard T.

1999-01-01

The electrically switched ion exchange (ESIX) process, being developed at Pacific Northwest National Laboratory, provides an alternative separation method to selectively remove ions from process and waste streams. In the ESIX process, in which an electroactive ion exchange film is deposited onto a high surface area electrode, uptake and elution are controlled directly by modulating the electrochemical potential of the film. This paper addresses engineering issues necessary to fully develop ESIX for specific industrial alkali cation separation challenges. The cycling and chemical stability and alkali cation selectivity of nickel hexacyanoferrate (NiHCF) electroactive films were investigated. The selectivity of NiHCF was determined using cyclic voltammetry and a quartz crystal microbalance to quantify ion uptake in the film. Separation factors indicated a high selectivity for cesium and a moderate selectivity for potassium in high sodium content solutions. A NiHCF film with improved redox cycling and chemical stability in a simulated pulp mill process stream, a targeted application for ESIX, was also prepared and tested

Buying Food on Sale: A Mixed Methods Study With Shoppers at an Urban Supermarket, Philadelphia, Pennsylvania, 2010–2012

Science.gov (United States)

Kumanyika, Shiriki K.; Stites, Shana D.; Singletary, S. Brook; Cooblall, Clarissa; DiSantis, Katherine Isselmann

2014-01-01

Introduction The obesity epidemic has drawn attention to food marketing practices that may increase the likelihood of caloric overconsumption and weight gain. We explored the associations of discounted prices on supermarket purchases of selected high-calorie foods (HCF) and more healthful, low-calorie foods (LCF) by a demographic group at high risk of obesity. Methods Our mixed methods design used electronic supermarket purchase data from 82 low-income (primarily African American female) shoppers for households with children and qualitative data from focus groups with demographically similar shoppers. Results In analyses of 6,493 food purchase transactions over 65 weeks, the odds of buying foods on sale versus at full price were higher for grain-based snacks, sweet snacks, and sugar-sweetened beverages (odds ratios: 6.6, 5.9, and 2.6, respectively; all P supermarket sales promotions from price reductions for HCF to price reductions for LCF might help prevent obesity by decreasing purchases of HCF. PMID:25188276

Electrochemical behavior of ruthenium-hexacyanoferrate modified glassy carbon electrode and catalytic activity towards ethanol electro oxidation

Energy Technology Data Exchange (ETDEWEB)

Costa, Wendell M.; Marques, Aldalea L.B., E-mail: aldalea.ufma@hotmail.com [Universidade Federal do Maranhao (UFMA), Sao Luis, MA (Brazil). Departamento de Quimica Tecnologica; Cardoso, William S.; Marques, Edmar P.; Bezerra, Cicero W.B. [Universidade Federal do Maranhao (UFMA), Sao Luis, MA (Brazil). Departamento de Qumica; Ferreira, Antonio Ap. P. [Universidade Estadual Paulista Julio de Mesquita Filho (UNESP), Araraquara, SP (Brazil). Instituto de Quimica; Song, Chaojie; Zhang, Jiujun [Energy, Mining and Environment Portfolio, National Research Council of Canada, Vancouver, BC (Canada)

2013-04-15

Ruthenium-based hexacyanoferrate (RuHCF) thin film modified glassy carbon electrode was prepared by drop evaporation method. The RuHCF modified electrode exhibited four redox couples in strong acidic solution (pH 1.5) attributed to Fe(CN){sub 6}{sup 3-} ion and three ruthenium forms (Ru(II), Ru(III) and Ru(IV)), characteristic of ruthenium oxide compounds. The modified electrode displayed excellent electrocatalytic activity towards ethanol oxidation in the potential region where electrochemical processes Ru(III)-O-Ru(IV) and Ru(IV)-O-Ru(VI) occur. Impedance spectroscopy data indicated that the charge transfer resistance decreased with the increase of the applied potential and ethanol concentration, indicating the use of the RuHCF modified electrode as an ethanol sensor. Under optimized conditions, the sensor responded linearly and rapidly to ethanol concentration between 0.03 and 0.4 mol L{sup -1} with a limit of detection of 0.76 mmol L{sup -1}, suggesting an adequate sensitivity in ethanol analyses. (author)

HANARO Neutron Radiography Facility and Fuel Cell Research

International Nuclear Information System (INIS)

Kim, Taejoo

2013-01-01

Fuel cell which generates electric energy from hydrogen and oxygen is one of noticed renewable energy system because this has high efficiency and free from CO 2 . Especially, PEMFC (Polymer Electrolyte Membrane Fuel Cell) is focused by automotive companies because PEMFC, which has high power rate per volume and low operating temperature (60∼80), is suited due to the compact design and short start-up time. The water management is one of the most critical issues for fuel cell commercialization. In order to make a proper scheme for water management, thein formation of water distribution and behavior is very important. Neutron imaging is the best method to visualize the water at fuel cell and has been applied worldwide with qualitative and quantitative results. Because the NRF has large beam size (350Χ450mm 2 ) and relatively high neutron flux (2Χ107 n/cm 2 sec), it is suitable for large scale fuel cell research. Neutron imaging technique was used to investigate the water distribution and behavior in PEMFC under different operating conditions. The NRF has contributed the improvement of fuel cell performance and is one of the best choices for fuel cell study

Pore-filled electrolyte membranes for facile fabrication of long-term stable dye-sensitized solar cells

International Nuclear Information System (INIS)

Seo, Seok-Jun; Cha, Hyeon-Jung; Kang, Yong Soo; Kang, Moon-Sung

2015-01-01

Graphical abstract: Display Omitted -- Highlights: •Pore-filled film electrolytes (PFEMs) were investigated for facile DSSC fabrication. •Optimal mixed solvent was suggested to enhance the long-term stability of DSSCs. •The PFEMs promised both the excellent thermal stability and energy efficiency. •Thephotovoltaic efficiency was well correlated with porous structure of substrates. -- ABSTRACT: Pore-filled electrolyte membranes (PFEMs) have been prepared by employing an optimized porous substrate and stable electrolyte composition for a facile manufacturing process of dye-sensitized solar cells (DSSCs). The PFEMs could be easily loaded into a photovoltaic device without adding a traditional electrolyte injection through a hole. In order to meet the requirements of both high energy conversion efficiency and proper long-term stability, three different solvents with high boiling point, i.e. valeronitrile, dimethyl sulfoxide, and dimethylacetamide, were appropriately mixed as a volumetric ratio of 7:2:1, respectively. As a result, similar conductivity and viscosity as well as better chemical stability were obtained compared to those of conventional 3-methoxypropionitrile-based electrolyte. In addition, linear relations were observed between the photovoltaic efficiency and porous film properties (i.e. porosity and tortuosity). The DSSC employing the PFEM doped with the mixed solvent based electrolyte exhibited the photon-to-current conversion efficiency of 6.30% at one sun condition. Moreover, the long-term stability test fixed at an elevated temperature of 85 °C exhibited outstanding durability of DSSC for 500 h

Facility Decontamination and Decommissioning Program Surveillance and Maintenance Plan, Revision 2

Energy Technology Data Exchange (ETDEWEB)

Poderis, Reed J. [NSTec; King, Rebecca A. [NSTec

2013-09-30

This Surveillance and Maintenance (S&M) Plan describes the activities performed between deactivation and final decommissioning of the following facilities located on the Nevada National Security Site, as documented in the Federal Facility Agreement and Consent Order under the Industrial Sites program as decontamination and decommissioning sites: ? Engine Maintenance, Assembly, and Disassembly (EMAD) Facility: o EMAD Building (Building 25-3900) o Locomotive Storage Shed (Building 25-3901) ? Test Cell C (TCC) Facility: o Equipment Building (Building 25-3220) o Motor Drive Building (Building 25-3230) o Pump Shop (Building 25-3231) o Cryogenic Lab (Building 25-3232) o Ancillary Structures (e.g., dewars, water tower, piping, tanks) These facilities have been declared excess and are in various stages of deactivation (low-risk, long-term stewardship disposition state). This S&M Plan establishes and implements a solid, cost-effective, and balanced S&M program consistent with federal, state, and regulatory requirements. A graded approach is used to plan and conduct S&M activities. The goal is to maintain the facilities in a safe condition in a cost-effective manner until their final end state is achieved. This plan accomplishes the following: ? Establishes S&M objectives and framework ? Identifies programmatic guidance for S&M activities to be conducted by National Security Technologies, LLC, for the U.S. Department of Energy, National Nuclear Security Administration Nevada Field Office (NNSA/NFO) ? Provides present facility condition information and identifies hazards ? Identifies facility-specific S&M activities to be performed and their frequency ? Identifies regulatory drivers, NNSA/NFO policies and procedures, and best management practices that necessitate implementation of S&M activities ? Provides criteria and frequencies for revisions and updates ? Establishes the process for identifying and dispositioning a condition that has not been previously identified or

The development of a mobile hot cell facility for the conditioning of spent high activity radioactive sources (SHARS)

International Nuclear Information System (INIS)

Liebenberg, G.R.; Al-Mughrabi, M.

2008-01-01

The International Atomic Energy Agency (IAEA) Waste Technology Section with additional support from the U.S. National Nuclear Security Agency (NNSA) through the IAEA Nuclear Security Fund has funded the design, fabrication, evaluation, and testing of a portable hot cell intended to address the problem of disused SHARS in obsolete irradiation devices such as teletherapy heads and dry irradiators. The project is initially targeting the African continent but expected soon to expand to Latin America and Asia. This hot cell would allow source removal, characterization, consolidation, repackaging in modern storage shields, and secure storage of high risk SHARS at single sites in each IAEA Member State. The mobile hot cell and related equipment is transported in two shipping containers to a specific country where the following process takes place: 1-) Assembly of hot cell; 2-) Removal of SHARS from working shields, encapsulation into a stainless steel capsule and placement into a long term storage shield; 3-) Conditioning of any other spent sources the country may require; 4-) Dismantling of the hot cell; 5-) Shipping equipment out of country. The operation in a specific country is planned to be executed over a three week period. This presentation will discuss the development of the mobile hot cell facility as well as the demonstration of the state of readiness of the system for manipulation of SHARS and the planned execution of the conditioning operations. As a result of this project, excess SHARS could be managed safely and securely and possibly be more easily repatriated to their country of origin for appropriate final disposition. (author)

Unique life sciences research facilities at NASA Ames Research Center

Science.gov (United States)

Mulenburg, G. M.; Vasques, M.; Caldwell, W. F.; Tucker, J.

1994-01-01

The Life Science Division at NASA's Ames Research Center has a suite of specialized facilities that enable scientists to study the effects of gravity on living systems. This paper describes some of these facilities and their use in research. Seven centrifuges, each with its own unique abilities, allow testing of a variety of parameters on test subjects ranging from single cells through hardware to humans. The Vestibular Research Facility allows the study of both centrifugation and linear acceleration on animals and humans. The Biocomputation Center uses computers for 3D reconstruction of physiological systems, and interactive research tools for virtual reality modeling. Psycophysiological, cardiovascular, exercise physiology, and biomechanical studies are conducted in the 12 bed Human Research Facility and samples are analyzed in the certified Central Clinical Laboratory and other laboratories at Ames. Human bedrest, water immersion and lower body negative pressure equipment are also available to study physiological changes associated with weightlessness. These and other weightlessness models are used in specialized laboratories for the study of basic physiological mechanisms, metabolism and cell biology. Visual-motor performance, perception, and adaptation are studied using ground-based models as well as short term weightlessness experiments (parabolic flights). The unique combination of Life Science research facilities, laboratories, and equipment at Ames Research Center are described in detail in relation to their research contributions.

Detonation cell size measurements in high-temperature hydrogen-air-steam mixtures at the BNL high-temperature combustion facility

International Nuclear Information System (INIS)

Ciccarelli, G.; Ginsberg, T.; Boccio, J.L.

1997-11-01

The High-Temperature Combustion Facility (HTCF) was designed and constructed with the objective of studying detonation phenomena in mixtures of hydrogen-air-steam at initially high temperatures. The central element of the HTCF is a 27-cm inner-diameter, 21.3-m long cylindrical test vessel capable of being heating to 700K ± 14K. A unique feature of the HTCF is the 'diaphragmless' acetylene-oxygen gas driver which is used to initiate the detonation in the test gas. Cell size measurements have shown that for any hydrogen-air-steam mixture, increasing the initial mixture temperature, in the range of 300K to 650K, while maintaining the initial pressure of 0.1 MPa, decreases the cell size and thus makes the mixture more detonable. The effect of steam dilution on cell size was tested in stoichiometric and off-stoichiometric (e.g., equivalence ratio of 0.5) hydrogen-air mixtures. Increasing the steam dilution in hydrogen-air mixtures at 0.1 MPa initial pressure increases the cell size, irrespective of initial temperature. It is also observed that the desensitizing effect of steam diminished with increased initial temperature. A 1-dimensional, steady-state Zel'dovich, von Neumann, Doring (ZND) model, with full chemical kinetics, has been used to predict cell size for hydrogen-air-steam mixtures at different initial conditions. Qualitatively the model predicts the overall trends observed in the measured cell size versus mixture composition and initial temperature and pressure. It was found that the proportionality constant used to predict detonation cell size from the calculated ZND model reaction zone varies between 10 and 100 depending on the mixture composition and initial temperature. 32 refs., 35 figs

Operation of post-irradiation examination facility

Energy Technology Data Exchange (ETDEWEB)

Kim, E. G.; Jeon, Y. B.; Ku, D. S.

1996-12-01

In 1996, the post-irradiation examination(PIE) of nuclear fuels was performed as follows. It has been searched for the caution of defection of defected fuel rods of Youngkwang-4 reactor through NDT and metallographic examination that had been required by KEPCO. And in-pool inspection of Kori-1 spent fuel assembly(FO2) was carried out. HVAC system and pool water treatment system have been operated to maintain the facility safely, and electric power supply system was checked and maintained for the normal and steady supply electric power to the facility. Image processing software was developed for measurement of defection of spent fuel rods. Besides, a radiation shielding glove box was fabricated and a hot cell compressor for volume reduction of radioactive materials was fabricated and installed in hot cell. Safeguards of nuclear materials were implemented in strict accordance with the relevant Korean rules and regulations as well as the international non-proliferation regime. Also the IAEA inspection was carried out on the quarterly basis. (author). 31 tabs., 71 figs., 4 refs.

Facilities for radiotherapy with ion beams status and worldwide developments

CERN Document Server

Wolf, B H

1999-01-01

Forty-five years after the first ion beam therapy in Berkeley around 25,000 cancer patients worldwide have been treated successfully. Ion accelerators, designed for nuclear research, delivered most of this treatment. The first hospital-based facility started operation in 1998 at Loma Linda California, the first for heavier ions at Chiba, Japan in 1994 and the first commercially delivered facilities started operation in 1998 at Kashiwa, Japan. In 2000, the Harvard Medical Centre, Boston, US, will commence operation and several new facilities are planned or under construction worldwide, although none in Australia. This paper will discuss the physical and biological advantages of ion beams over x-rays and electrons. In the treatment of cancer patients ion beam therapy is especially suited for localised tumours in radiation sensitive areas like skull or spine. Heavier ions are also effective in anoxic tumour cells (found around the normally oxygenated cell population). An additional advantage of the heavier carbo...

Advanced Casting Technology

Science.gov (United States)

1982-08-01

Anodic Films for the Protection of Magnesium Alloys". G.R. Kotler, D.L. Hawke and E.N. Agua . Proc. International Magnesium Association, Montreal, May...HCF testing, impellers were bench tested to assess the in situ fatigue capabilities of 250-C28 impeller airfoils. In this testing, the airfoils...64 at 204oC (400oF), 13- T to a> o >-, o r- i—l CD -*—• Cast Wrought TE-2222 Ficure 11. In situ HCF results for Ti-64 Model 250

Venezuela electoral 2012: escenarios y perspectivas

Directory of Open Access Journals (Sweden)

Juan Manuel Trak Vásquez

2014-06-01

Full Text Available El objetivo de estas líneas es reflexionar sobre los posibles escenarios que se pueden dar en Venezuela a partir de las elecciones presidenciales del 7 de octubre, en donde se juega la reelección de Hugo Chávez Frías (HCF. Para ello es necesario hacer un breve recorrido por la historia política reciente de Venezuela, cómo llega HCF al poder y los hitos más importantes que han marcado sus mandatos desde 1998.

Technical study of a thermally dense long term interim storage facility

International Nuclear Information System (INIS)

Le Duigou, A.; Badie, M.; Duret, B.; Bricard, A.

2001-01-01

The COFRE concept is aimed at the surface and thermal densification of the interim storage facility for irradiated fuels. The facility provides the biological shielding. A conditioning cell is used to load and retrieve the fuel assemblies. The facility container is the second containment barrier. The high power levels are managed by an auxiliary cooling system whose original feature is the passive use of a water evaporation-condensation cycle in a sealed circuit. The removable evaporator abuts the container. The air cooled condenser is placed outside the facility. Contact resistance and heat pipe mode were successfully modelled and are undergoing experimental validation on the THERESE and REBECA loops. (author)

Installation of Tc-99m generator manufacturing facilities

International Nuclear Information System (INIS)

Shin, B. C.; Choung, W. M.; Park, J. H.; Park, S. H.; Kim, S. J.; Park, K. B.

2004-01-01

For the characteristics of radiopharmaceuticals, the manufacturing facility should be complied with the radiation safety standards for operators as well as GMP (Good Manufacturing Practice) cleanness standards for production. We intensively modified the existing Radioisotope production facilities, which were installed only in radiation safety points of view, to meet cleanness criteria. And the concept of multi-barrier buffer zones was introduced to apply negative air pressure for hot cell with first priority and to continue relative positive air pressure for clean room. The manufacturing area for Tc-99m Generator can be entered only through a second change. The doors of each change area are interlocked to maintain air pressure differentials. The pass box for material transfer are also interlocked so that only one side may be opened at any one time to keep cleanness. Two door-type autoclave was installed crossing the wall between preparing room and aseptic room to keep cleanness after sterilization. Three lead hot cells were installed and final inspection including gamma survey test were performed. The clean room was installed and TAB for this facility was performed in order to acquire the necessary air flow. The filter bank for filtration of exhausted radiation air was installed and its efficiency test was performed. In this facility, radiation shielding utilities and manufacturing instruments were set up and their operating manuals were documented. Efficiency tests for every utilities and instruments were satisfied and the approval for use of the facilities was achieved from MOST (Ministry of Science and Technology). The Sam Young Unitech, the lessee of the facilities set up the equipment in the hot cell, which is needed to produce Tc-99m Generator, supported by IPPE in Russia. They are composing the systems complied with the guidelines and the regulations, and keep in contact to KFDA for acquiring its approval. It is expected to produce Tc-99m Generator within

Scalable Fabrication of Efficient NiCo2S4 Counter Electrodes for Dye-sensitized Solar Cells Using a Facile Solution Approach

International Nuclear Information System (INIS)

Su, An-Lin; Lu, Man-Ning; Chang, Chin-Yu; Wei, Tzu-Chien; Lin, Jeng-Yu

2016-01-01

Exploiting highly electrocatalytic and cost-effectiveness counter electrodes (CEs) in dye-sensitized solar cells (DSCs) has been regarded as a persistent objective. In this work, we proposed a facile low-cost solution approach for scalable fabrication of NiCo 2 S 4 (NCS) CEs in Pt-free DSCs. Firstly, NCS particles were synthesized by means of a solvothermal method. Afterwards, the NCS particles were successfully immobilized on fluorine-doped tin oxide (FTO) glass substrate and indium doped tin oxide polyethylene naphthalate (ITO/PEN) flexible substrate as NCS CE and flexible NCS CE, respectively, by using series of dip-coating processes. On the basis of extensive electrochemical characterizations, the NCS CEs displayed Pt-like electrocatalytic activity for I 3 − reduction. The DSC based on the NCS CE achieved an impressive cell efficiency of 8.94%, which was higher than that of the cell with the conventional Pt CE (8.51%). More interesting, the DSC using the flexible NCS CE still demonstrated an acceptable cell performance of 8.62% (or 8.57% with the bended flexible NCS CE).

Status of spent fuel storage facilities in Switzerland

International Nuclear Information System (INIS)

Beyeler, P.C.; Lutz, H.R.; Heesen, W. von

1999-01-01

Planning of a dry spent fuel storage facility in Switzerland started already 15 years ago. The first site considered for a central interim storage facility was the cavern of the decommissioned pilot nuclear plant at Lucens in the French-speaking part of Switzerland. This project was terminated in the late eighties because of lack of public acceptance. The necessary acceptance was found in the small town of Wuerenlingen which has hosted for many years the Swiss Reactor Research Centre. The new project consists of centralised interim storage facilities for all types of radioactive waste plus a hot cell and a conditioning and incinerating facility. It represents a so-called integrated storage solution. In 1990, the new company 'ZWILAG Zwischenlager Wuerenlingen AG' (ZWILAG) was founded and the licensing procedures according to the Swiss Atomic law were initiated. On August 26, 1996 ZWILAG got the permit for construction of the whole facility including the operating permit for the storage facilities. End of construction and commissioning are scheduled for autumn 1999. The nuclear power station Beznau started planning a low level waste and spent fuel storage facility on its own, because in 1990 its management thought that by 1997 the first high active waste from the reprocessing facilities in France would have to be taken back. This facility at the Beznau site, called ZWIBEZ, was licensed according to a shorter procedure so its construction was finished by 1997. The two facilities for high level waste and spent fuel provide space for a total of 278 casks, which is sufficient for the waste and spent fuel of the four Swiss nuclear power stations including their life extension programme. (author)

Dismantling of the 904 Cell at the HAO/Sud Facility - 13466

Energy Technology Data Exchange (ETDEWEB)

Vaudey, C.E.; Crosnier, S. [AREVA Clean-Up BU, 1 route de la Noue 91196 - Gif-sur-Yvette (France); Renouf, M.; Gaspard, N. [AREVA Clean-Up BU, Site de La Hague - BV 35 - 50444 Beaumont Hague (France); Pinot, L. [AREVA D and D BU, Site de La Hague - 50444 Beaumont Hague (France)

2013-07-01

La Hague facility, in France, is the spent fuel recycling plant wherein a part of the fuel coming from some of the French, German, Belgian, Swiss, Dutch and Japanese nuclear reactors is reprocessed before being recycled in order to separate certain radioactive elements. The facility has been successively handled by the CEA (1962-1978), Cogema (1978-2006), and AREVA NC (since 2006). La Hague facility is composed of 3 production units: The UP2-400 production unit started to be operated in 1966 for the reprocessing of UNGG metal fuel. In 1976, following the dropout of the graphite-gas technology by EDF, an HAO workshop to reprocess the fuel from the light water reactors is affiliated and then stopped in 2003. - UP2-400 is partially stopped in 2002 and then definitely the 1 January 2004 and is being dismantled - UP2-800, with the same capacity than UP3, started to be operated in 1994 and is still in operation. And UP3 - UP3 was implemented in 1990 with an annual reprocessing capacity of 800 tons of fuel and is still in operation The combined licensed capacity of UP2-800 and UP3 is 1,700 tons of used fuel. (authors)

Conceptual design of a technology development facility (TDF)

International Nuclear Information System (INIS)

Doggett, J.N.; Damm, C.C.

1981-01-01

We have developed a concept for employing a single-cell mirror machine in a facility for testing and developing fusion reactor materials, components, and subsystems in a fusion reactor environment. Our approach is similar to that of the 1974 FERF study, except that we have added an auxiliary thermal-barrier cell at each end of the yin-yang magnet. In this way, we provide for plasma microstability by confining a warm plasma component between potential peaks at each end of the device (just as in the tandem mirror with auxiliary barrier cells) while we further improve confinement by the inherent reduction in ambipolar potential drop in the central cell

Facility effluent monitoring plan determinations for the 400 Area facilities

International Nuclear Information System (INIS)

Nickels, J.M.

1991-09-01

This Facility Effluent Monitoring Plan determination resulted from an evaluation conducted for the Westinghouse Hanford Company 400 Area facilities on the Hanford Site. The Facility Effluent Monitoring Plan determinations have been prepared in accordance with A Guide for Preparing Hanford Site Facility Effluent Monitoring Plans. Two major Westinghouse Hanford Company facilities in the 400 Area were evaluated: the Fast Flux Test Facility and the Fuels Manufacturing and examination Facility. The determinations were prepared by Westinghouse Hanford Company. Of these two facilities, only the Fast Flux Test Facility will require a Facility Effluent Monitoring Plan. 7 refs., 5 figs., 4 tabs

Fire Hazard Analysis for the Cold Vacuum Drying facility (CVD) Facility

Energy Technology Data Exchange (ETDEWEB)

SINGH, G.

2000-09-06

The CVDF is a nonreactor nuclear facility that will process the Spent Nuclear Fuels (SNF) presently stored in the 105-KE and 105-KW SNF storage basins. Multi-canister overpacks (MCOs) will be loaded (filled) with K Basin fuel transported to the CVDF. The MCOs will be processed at the CVDF to remove free water from the fuel cells (packages). Following processing at the CVDF, the MCOs will be transported to the CSB for interim storage until a long-term storage solution can be implemented. This operation is expected to start in November 2000. A Fire Hazard Analysis (FHA) is required for all new facilities and all nonreactor nuclear facilities, in accordance with U.S. Department of Energy (DOE) Order 5480.7A, Fire Protection. This FHA has been prepared in accordance with DOE 5480.7A and HNF-PRO-350, Fire Hazard Analysis Requirements. Additionally, requirements or criteria contained in DOE, Richland Operations Office (RL) RL Implementing Directive (RLID) 5480.7, Fire Protection, or other DOE documentation are cited, as applicable. This FHA comprehensively assesses the risk of fire at the CVDF to ascertain whether the specific objectives of DOE 5480.7A are met. These specific fire protection objectives are: (1) Minimize the potential for the occurrence of a fire. (2) Ensure that fire does not cause an onsite or offsite release of radiological and other hazardous material that will threaten the public health and safety or the environment. (3) Establish requirements that will provide an acceptable degree of life safety to DOE and contractor personnel and ensure that there are no undue hazards to the public from fire and its effects in DOE facilities. (4) Ensure that vital DOE programs will not suffer unacceptable delays as a result of fire and related perils. (5) Ensure that property damage from fire and related perils does not exceed an acceptable level. (6) Ensure that process control and safety systems are not damaged by fire or related perils. This FHA is based on the

Fire Hazard Analysis for the Cold Vacuum Drying facility (CVD) Facility

International Nuclear Information System (INIS)

SINGH, G.

2000-01-01

The CVDF is a nonreactor nuclear facility that will process the Spent Nuclear Fuels (SNF) presently stored in the 105-KE and 105-KW SNF storage basins. Multi-canister overpacks (MCOs) will be loaded (filled) with K Basin fuel transported to the CVDF. The MCOs will be processed at the CVDF to remove free water from the fuel cells (packages). Following processing at the CVDF, the MCOs will be transported to the CSB for interim storage until a long-term storage solution can be implemented. This operation is expected to start in November 2000. A Fire Hazard Analysis (FHA) is required for all new facilities and all nonreactor nuclear facilities, in accordance with U.S. Department of Energy (DOE) Order 5480.7A, Fire Protection. This FHA has been prepared in accordance with DOE 5480.7A and HNF-PRO-350, Fire Hazard Analysis Requirements. Additionally, requirements or criteria contained in DOE, Richland Operations Office (RL) RL Implementing Directive (RLID) 5480.7, Fire Protection, or other DOE documentation are cited, as applicable. This FHA comprehensively assesses the risk of fire at the CVDF to ascertain whether the specific objectives of DOE 5480.7A are met. These specific fire protection objectives are: (1) Minimize the potential for the occurrence of a fire. (2) Ensure that fire does not cause an onsite or offsite release of radiological and other hazardous material that will threaten the public health and safety or the environment. (3) Establish requirements that will provide an acceptable degree of life safety to DOE and contractor personnel and ensure that there are no undue hazards to the public from fire and its effects in DOE facilities. (4) Ensure that vital DOE programs will not suffer unacceptable delays as a result of fire and related perils. (5) Ensure that property damage from fire and related perils does not exceed an acceptable level. (6) Ensure that process control and safety systems are not damaged by fire or related perils. This FHA is based on the

Preliminary definition of the remote handling system for the current IFMIF Test Facilities

Energy Technology Data Exchange (ETDEWEB)

Queral, V., E-mail: vicentemanuel.queral@ciemat.es [Laboratorio Nacional de Fusion, EURATOM-CIEMAT, 28040 Madrid (Spain); Urbon, J. [Laboratorio Nacional de Fusion, EURATOM-CIEMAT, 28040 Madrid (Spain); Instituto de Fusion Nuclear, Universidad Politecnica de Madrid, 28006 Madrid (Spain); Garcia, A.; Cuarental, I.; Mota, F. [Laboratorio Nacional de Fusion, EURATOM-CIEMAT, 28040 Madrid (Spain); Micciche, G. [CR ENEA Brasimone, I-40035 Camugnano (BO) (Italy); Ibarra, A. [Laboratorio Nacional de Fusion, EURATOM-CIEMAT, 28040 Madrid (Spain); Rapisarda, D. [Laboratorio Nacional de Fusion, EURATOM-CIEMAT, 28040 Madrid (Spain); Instituto de Fusion Nuclear, Universidad Politecnica de Madrid, 28006 Madrid (Spain); Casal, N. [Laboratorio Nacional de Fusion, EURATOM-CIEMAT, 28040 Madrid (Spain)

2011-10-15

A coherent design of the remote handling system with the design of the components to be manipulated is vital for reliable, safe and fast maintenance, having a decisive impact on availability, occupational exposures and operational cost of the facility. Highly activated components in the IFMIF facility are found at the Test Cell, a shielded pit where the samples are accurately located. The remote handling system for the Test Cell reference design was outlined in some past IFMIF studies. Currently a new preliminary design of the Test Cell in the IFMIF facility is being developed, introducing important modifications with respect to the reference one. This recent design separates the previous Vertical Test Assemblies in three functional components: Test Modules, shielding plugs and conduits. Therefore, it is necessary to adapt the previous design of the remote handling system to the new maintenance procedures and requirements. This paper summarises such modifications of the remote handling system, in particular the assessment of the feasibility of a modified commercial multirope crane for the handling of the weighty shielding plugs for the new Test Cell and a quasi-commercial grapple for the handling of the new Test Modules.

Preliminary definition of the remote handling system for the current IFMIF Test Facilities

International Nuclear Information System (INIS)

Queral, V.; Urbon, J.; Garcia, A.; Cuarental, I.; Mota, F.; Micciche, G.; Ibarra, A.; Rapisarda, D.; Casal, N.

2011-01-01

A coherent design of the remote handling system with the design of the components to be manipulated is vital for reliable, safe and fast maintenance, having a decisive impact on availability, occupational exposures and operational cost of the facility. Highly activated components in the IFMIF facility are found at the Test Cell, a shielded pit where the samples are accurately located. The remote handling system for the Test Cell reference design was outlined in some past IFMIF studies. Currently a new preliminary design of the Test Cell in the IFMIF facility is being developed, introducing important modifications with respect to the reference one. This recent design separates the previous Vertical Test Assemblies in three functional components: Test Modules, shielding plugs and conduits. Therefore, it is necessary to adapt the previous design of the remote handling system to the new maintenance procedures and requirements. This paper summarises such modifications of the remote handling system, in particular the assessment of the feasibility of a modified commercial multirope crane for the handling of the weighty shielding plugs for the new Test Cell and a quasi-commercial grapple for the handling of the new Test Modules.

Construction of solid waste form test facility

International Nuclear Information System (INIS)

Park, Hyun Whee; Lee, Kang Moo; Koo, Jun Mo; Jung, In Ha; Lee, Jong Ryeul; Kim, Sung Whan; Bae, Sang Min; Cho, Kang Whon; Sung, Suk Jong

1989-02-01

The Solid Waste Form Test Facility (SWFTF) is now construction at DAEDUCK in Korea. In SWFTF, the characteristics of solidified waste products as radiological homogeneity, mechanical and thermal property, water resistance and lechability will be tested and evaluated to meet conditions for long-term storage or final disposal of wastes. The construction of solid waste form test facility has been started with finishing its design of a building and equipments in Sep. 1984, and now building construction is completed. Radioactive gas treatment system, extinguishers, cooling and heating system for the facility, electrical equipments, Master/Slave manipulator, power manipulator, lead glass and C.C.T.V. has also been installed. SWFTF will be established in the beginning of 1990's. At this report, radiation shielding door, nondestructive test of the wall, instrumentation system for the utility supply system and cell lighting system are described. (Author)

A national facility for biological cryo-electron microscopy

International Nuclear Information System (INIS)

Saibil, Helen R.; Grünewald, Kay; Stuart, David I.

2015-01-01

This review provides a brief update on the use of cryo-electron microscopy for integrated structural biology, along with an overview of the plans for the UK national facility for electron microscopy being built at the Diamond synchrotron. Three-dimensional electron microscopy is an enormously powerful tool for structural biologists. It is now able to provide an understanding of the molecular machinery of cells, disease processes and the actions of pathogenic organisms from atomic detail through to the cellular context. However, cutting-edge research in this field requires very substantial resources for equipment, infrastructure and expertise. Here, a brief overview is provided of the plans for a UK national three-dimensional electron-microscopy facility for integrated structural biology to enable internationally leading research on the machinery of life. State-of-the-art equipment operated with expert support will be provided, optimized for both atomic-level single-particle analysis of purified macromolecules and complexes and for tomography of cell sections. The access to and organization of the facility will be modelled on the highly successful macromolecular crystallography (MX) synchrotron beamlines, and will be embedded at the Diamond Light Source, facilitating the development of user-friendly workflows providing near-real-time experimental feedback

Loading of Hip Measured by Hip Contact Forces at Different Speeds of Walking and Running.

Science.gov (United States)

Giarmatzis, Georgios; Jonkers, Ilse; Wesseling, Mariska; Van Rossom, Sam; Verschueren, Sabine

2015-08-01

Exercise plays a pivotal role in maximizing peak bone mass in adulthood and maintaining it through aging, by imposing mechanical loading on the bone that can trigger bone mineralization and growth. The optimal type and intensity of exercise that best enhances bone strength remains, however, poorly characterized, partly because the exact peak loading of the bone produced by the diverse types of exercises is not known. By means of integrated motion capture as an input to dynamic simulations, contact forces acting on the hip of 20 young healthy adults were calculated during walking and running at different speeds. During walking, hip contact forces (HCFs) have a two-peak profile whereby the first peak increases from 4.22 body weight (BW) to 5.41 BW and the second from 4.37 BW to 5.74 BW, by increasing speed from 3 to 6 km/h. During running, there is only one peak HCF that increases from 7.49 BW to 10.01 BW, by increasing speed from 6 to 12 km/h. Speed related profiles of peak HCFs and ground reaction forces (GRFs) reveal a different progression of the two peaks during walking. Speed has a stronger impact on peak HCFs rather than on peak GRFs during walking and running, suggesting an increasing influence of muscle activity on peak HCF with increased speed. Moreover, results show that the first peak of HCF during walking can be predicted best by hip adduction moment, and the second peak of HCF by hip extension moment. During running, peak HCF can be best predicted by hip adduction moment. The present study contributes hereby to a better understanding of musculoskeletal loading during walking and running in a wide range of speeds, offering valuable information to clinicians and scientists exploring bone loading as a possible nonpharmacological osteogenic stimulus. © 2015 American Society for Bone and Mineral Research. © 2015 American Society for Bone and Mineral Research.

Study on High energy efficiency photovoltaic facility agricultural system in tropical area of China

Directory of Open Access Journals (Sweden)

Ge Zhiwu

2018-01-01

Full Text Available The photovoltaic facility agriculture is developing rapidly in recent years, but there are many problems brought out, even in some important demonstration projects, due to the lack of standards. In order to solve some of these problems, we set up a photovoltaic facilities agricultural system in Guilinyang University City, Haikou, China and make an in-depth study on the photovoltaic facility agricultural system and its related problems. In this paper we disclose some of the experimental results. We plant corianders under two kinds of solar cell panels and general double glass assembly already sold on the market. Experiments showed that the square format cell panels are much better than row type, and the next one is general double glass assembly sold on the market, the last is the case without any shelter. 30 days after planting, the height of coriander plants are 50mm, 30mm, 23mm and 20mm correspondingly. The two typical solar cell panels have gaps between cells, and can save much more energy and improve power generation efficiency, we arrange the panels at optimum tilted angle, and design the system as open structure to save more energy. The photovoltaic facilities agricultural system we set up in Guilinyang University City can achieve much high solar energy efficiency than others and has broad application prospects.

Polymer Solar Cells with Efficiency >10% Enabled via a Facile Solution-Processed Al-Doped ZnO Electron Transporting Layer

KAUST Repository

Jagadamma, Lethy Krishnan

2015-04-22

A facile and low-temperature (125 °C) solution-processed Al-doped ZnO (AZO) buffer layer functioning very effectively as electron accepting/hole blocking layer for a wide range of polymer:fullerene bulk heterojunction systems, yielding power conversion efficiency in excess of 10% (8%) on glass (plastic) substrates is described. The ammonia-treatment of the aqueous AZO nanoparticle solution produces compact, crystalline, and smooth thin films, which retain the aluminum doping, and eliminates/reduces the native defects by nitrogen incorporation, making them good electron transporters and energetically matched with the fullerene acceptor. It is demonstrated that highly efficient solar cells can be achieved without the need for additional surface chemical modifications of the buffer layer, which is a common requirement for many metal oxide buffer layers to yield efficient solar cells. Also highly efficient solar cells are achieved with thick AZO films (>50 nm), highlighting the suitability of this material for roll-to-roll coating. Preliminary results on the applicability of AZO as electron injection layer in F8BT-based polymer light emitting diode are also presented. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Georgetown University Photovoltaic Higher Education National Exemplar Facility (PHENEF)

Science.gov (United States)

Marshall, N.

1984-01-01

Several photographs of this facility using photovoltaic (PV) cells are shown. An outline is given of the systems requirements, system design and wiring topology, a simplified block design, module electrical characteristics, PV module and PV module matching.

Performance Evaluation Facility for Fire Fighting Thermal Imager

International Nuclear Information System (INIS)

Kim, Sung Chan; Amon, Francine; Hamins, Anthony

2007-01-01

The present study investigates the characteristics of obscuring media inside an optical smoke cell, which is a bench-scale testing facility for the evaluation of thermal imaging cameras used by fire fighters. Light extinction coefficient and visibility through the smoke cell is characterized by the measured laser transmittance. The laser transmittance along the axial direction of the smoke cell is relatively uniform at upper and lower part for various air/fuel volume flow rate. Contrast level based image quality of visible CCD camera through the smoke cell is compared with that of thermal imaging camera. The optical smoke cell can be used as well-controlled and effective laboratory-scale test apparatus to evaluate the performance of thermal imaging camera for fire fighting application

New irradiation facilities at the Australian national medical cyclotron

International Nuclear Information System (INIS)

Parcell, S.K.; Arnott, D.W.; Conard, E.M.

1999-01-01

Two new irradiation facilities have been developed at the National Medical Cyclotron for radionuclide production. The first relocates PET irradiations from the cyclotron vault to a dedicated PET beam room, to improve accessibility and reduce radiation exposures associated with target maintenance. This new facility consists of a beam line to transport 16-30 MeV proton beams from the cyclotron to 1 of 8 PET targets mounted on a target rack. The target rack has increased the number of targets available for production and experimentation. The second is a completely independent solid target irradiation facility for SPECT. This facility consists of a beam line to transport 26-30 MeV proton beams from the cyclotron to a dedicated beam room containing one solid target station. A new pneumatic target transfer system was also developed to transport the solid target to and from the existing chemistry hot cells. The beam line and target components are operated under the control of a dedicated PLC with a PC based user interface. The development and some technical aspects of these new irradiation facilities are discussed here. (author)

The Radiological Research Accelerator Facility:

International Nuclear Information System (INIS)

Hall, E.J.; Goldhagen, P.

1988-07-01

The Radiological Research Accelerator Facility (RARAF) is based on a 4-MV Van de Graaff accelerator, which is used to generated a variety of well-characterized radiation beams for research in radiobiology, radiological physics, and radiation chemistry. It is part of the Radiological Research Laboratory (RRL) of Columbia University, and its operation is supported as a National Facility by the U.S. Department of Energy. As such, RARAF is available to all potential users on an equal basis, and scientists outside the RRL are encouraged to submit proposals for experiments at RARAF. Facilities and services are provided to users, but the research projects themselves must be supported separately. RARAF was located at BNL from 1967 until 1980, when it was dismantled and moved to the Nevis Laboratories of Columbia University, where it was then reassembled and put back into operation. Data obtained from experiment using RARAF have been of pragmatic value to radiation protection and to neutron therapy. At a more fundamental level, the research at RARAF has provided insight into the biological action of radiation and especially its relation to energy distribution in the cell. High-LET radiations are an agent of special importance because they can cause measurable cellular effects by single particles, eliminating some of the complexities of multievent action and more clearly disclosing basic features. This applies particularly to radiation carcinogenesis. Facilities are available at RARAF for exposing objects to different radiations having a wide range of linear energy transfers (LETs)

Radiological Research Accelerator Facility. Progress report, April 1, 1984-March 31, 1985

International Nuclear Information System (INIS)

Rossi, H.H.

1985-01-01

The aim of the Radiological Research Accelerator Facility (RARAF) was to provide a source of monoenergetic neutrons for studies in radiation biology, dosimetry and microdosimetry. The research has provided insight into the biological action of radiation and its relation to energy distribution in the cell as described by the theory of dual radiation action. This status report on the facility includes descriptions of the capabilities and layout, staffing, radiation safety, and a chronological account of the development and use of the facilities. 5 references, 2 figures

Polymer solar cells with efficiency >10% enabled via a facile solution-processed Al-doped ZnO electron transporting layer

KAUST Repository

Jagadamma, Lethy Krishnan

2015-10-05

The present work details a facile and low-temperature (125C) solution-processed Al-doped ZnO (AZO) buffer layer functioning very effectively as electron accepting/hole blocking layer for a wide range of polymer:fullerene bulk heterojunction systems, and yielding power conversion efficiency in excess of 10% (8%) on glass (plastic) substrates. We show that ammonia addition to the aqueous AZO nanoparticle solution is a critically important step toward producing compact and smooth thin films which partially retain the aluminum doping and crystalline order of the starting AZO nanocrystals. The ammonia treatment appears to reduce the native defects via nitrogen incorporation, making the AZO film a very good electron transporter and energetically matched with the fullerene acceptor. Importantly, highly efficient solar cells are achieved without the need for additional surface chemical passivation or modification, which has become an increasingly common route to improving the performance of evaporated or solution-processed ZnO ETLs in solar cells.

Development of Infrastructure Facilities for Superconducting RF Cavity Fabrication, Processing and 2 K Characterization at RRCAT

Science.gov (United States)

Joshi, S. C.; Raghavendra, S.; Jain, V. K.; Puntambekar, A.; Khare, P.; Dwivedi, J.; Mundra, G.; Kush, P. K.; Shrivastava, P.; Lad, M.; Gupta, P. D.

2017-02-01

An extensive infrastructure facility is being established at Raja Ramanna Centre for Advanced Technology (RRCAT) for a proposed 1 GeV, high intensity superconducting proton linac for Indian Spallation Neutron Source. The proton linac will comprise of a large number of superconducting Radio Frequency (SCRF) cavities ranging from low beta spoke resonators to medium and high beta multi-cell elliptical cavities at different RF frequencies. Infrastructure facilities for SCRF cavity fabrication, processing and performance characterization at 2 K are setup to take-up manufacturing of large number of cavities required for future projects of Department of Atomic Energy (DAE). RRCAT is also participating in a DAE’s approved mega project on “Physics and Advanced technology for High intensity Proton Accelerators” under Indian Institutions-Fermilab Collaboration (IIFC). In the R&D phase of IIFC program, a number of high beta, fully dressed multi-cell elliptical SCRF cavities will be developed in collaboration with Fermilab. A dedicated facility for SCRF cavity fabrication, tuning and processing is set up. SCRF cavities developed will be characterized at 2K using a vertical test stand facility, which is already commissioned. A Horizontal Test Stand facility has also been designed and under development for testing a dressed multi-cell SCRF cavity at 2K. The paper presents the infrastructure facilities setup at RRCAT for SCRF cavity fabrication, processing and testing at 2K.

Dismantling and decontamination of the PIVER prototype vitrification facility

International Nuclear Information System (INIS)

Jouan, A.

1989-01-01

The PIVER facility was dismantled for replacement by a new continuous pilot plant. The more important operation concerns the vitrification cell, containing equipments of the process, for complete disposal and maximum decontamination, requiring dismantling, cutting, conditioning and removal of equipment inside the cell. Manipulators, handling and cutting tools were used. Activity of removed material and irradiation of personal are followed during the work for matching intervention means to operation conditions [fr

Fusion Materials Irradiation Test Facility: experimental capabilities and test matrix

International Nuclear Information System (INIS)

Opperman, E.K.

1982-01-01

This report describes the experimental capabilities of the Fusion Materials Irradiation Test Facility (FMIT) and reference material specimen test matrices. The description of the experimental capabilities and the test matrices has been updated to match the current single test cell facility ad assessed experimenter needs. Sufficient detail has been provided so that the user can plan irradiation experiments and conceptual hardware. The types of experiments, irradiation environment and support services that will be available in FMIT are discussed

Radiation shielding design for a hot repair facility

International Nuclear Information System (INIS)

Courtney, J.C.; Dwight, C.C.

1991-01-01

A new repair and decontamination area is being built to support operations at the demonstration fuel cycle facility for the Integral Fast Reactor program at Argonne National Laboratory's site at the Idaho National Engineering Laboratory. Provisions are made for remote, glove wall, and contact maintenance on equipment removed from hot cells where spent fuel will be electrochemically processed and recycled to the Experimental Breeder Reactor-II. The source for the shielding design is contamination from a mix of fission and activation products present on items removed from the hot cells. The repair facility also serves as a transfer path for radioactive waste produced by processing operations. Radiation shields are designed to limit dose rates to no more than 5 microSv h-1 (0.5 mrem h-1) in normally occupied areas. Point kernel calculations with buildup factors have been used to design the shielding and to position radiation monitors within the area

Pressure analysis in ventilation ducts at bituminization facility

International Nuclear Information System (INIS)

Kikuchi, Naoki; Iimura, Masato; Takahashi, Yuki; Omori, Eiichi; Yamanouchi, Takamichi

1997-09-01

Pressure analysis in cell ventilation ducts at bituminization facility where the fire and explosion accident occured was carried out. This report also describes the results of bench mark calculations for computer code EVENT84 which was used for the accident analysis. The bench mark calculations were performed by comparing the analytical results by EVENT84 code with the experimental data of safety demonstration tests of ventilation system which were carried out by JAERI. We confirmed the applicability of EVENT84 code with the conservative results. The pressure analysis in cell ventilation ducts at bituminization facility were performed by comparing the analytical results of duct pressure by EVENT84 code with the yield stress of destroyed ducts by explosion, in order to estimate the scale of explosion. As a result, we could not explain the damage of ducts quantitatively, but we found the local pressure peaks analytically in downstream ducts where the serious damages were observed. (author)

A national facility for biological cryo-electron microscopy.

Science.gov (United States)

Saibil, Helen R; Grünewald, Kay; Stuart, David I

2015-01-01

Three-dimensional electron microscopy is an enormously powerful tool for structural biologists. It is now able to provide an understanding of the molecular machinery of cells, disease processes and the actions of pathogenic organisms from atomic detail through to the cellular context. However, cutting-edge research in this field requires very substantial resources for equipment, infrastructure and expertise. Here, a brief overview is provided of the plans for a UK national three-dimensional electron-microscopy facility for integrated structural biology to enable internationally leading research on the machinery of life. State-of-the-art equipment operated with expert support will be provided, optimized for both atomic-level single-particle analysis of purified macromolecules and complexes and for tomography of cell sections. The access to and organization of the facility will be modelled on the highly successful macromolecular crystallography (MX) synchrotron beamlines, and will be embedded at the Diamond Light Source, facilitating the development of user-friendly workflows providing near-real-time experimental feedback.

Preliminary design for a maglev development facility

Energy Technology Data Exchange (ETDEWEB)

Coffey, H.T.; He, J.L.; Chang, S.L.; Bouillard, J.X.; Chen, S.S.; Cai, Y.; Hoppie, L.O.; Lottes, S.A.; Rote, D.M. (Argonne National Lab., IL (United States)); Zhang, Z.Y. (Polytechnic Univ., Brooklyn, NY (United States)); Myers, G.; Cvercko, A. (Sterling Engineering, Westchester, IL (United States)); Williams, J.R. (Alfred Benesch and Co., Chicago, IL (United States))

1992-04-01

A preliminary design was made of a national user facility for evaluating magnetic-levitation (maglev) technologies in sizes intermediate between laboratory experiments and full-scale systems. A technical advisory committee was established and a conference was held to obtain advice on the potential requirements of operational systems and how the facility might best be configured to test these requirements. The effort included studies of multiple concepts for levitating, guiding, and propelling maglev vehicles, as well as the controls, communications, and data-acquisition and -reduction equipment that would be required in operating the facility. Preliminary designs for versatile, dual 2-MVA power supplies capable of powering attractive or repulsive systems were developed. Facility site requirements were identified. Test vehicles would be about 7.4 m (25 ft) long, would weigh form 3 to 7 metric tons, and would operate at speeds up to 67 m/s (150 mph) on a 3.3-km (2.05-mi) elevated guideway. The facility would utilize modular vehicles and guideways, permitting the substitution of levitation, propulsion, and guideway components of different designs and materials for evaluation. The vehicle would provide a test cell in which individual suspension or propulsion components or subsystems could be tested under realistic conditions. The system would allow economical evaluation of integrated systems under varying weather conditions and in realistic geometries.

Omega: A 24-beam UV irradiation facility

International Nuclear Information System (INIS)

Richardson, M.C.; Beich, W.; Delettrez, J.

1985-01-01

The authors report on the characterization and performance of the 24-beam Omega laser facility under full third harmonic (351-nm) upconversion. This system provides for the first time a multibeam laser facility for the illumination of spherical targets with UV laser light in symmetric irradiation conditions with energies in the kilojoule range. This facility is capable of providing sufficient irradiation uniformity to test concepts of direct drive laser fusion with UV-driven ablation targets. The results of initial studies of ablatively driven DT-fueled glass microballoon targets will be described. The 24-beam Omega Nd:phosphate glass facility is capable of providing at 1054 nm output powers in excess of 10 TW in short ( 10 4 full system shots to date) irradiation facility with beam synchronism of approx. =3 psec, beam placement accuracy on target of 10 μm, and interbeam energy variance of approx. =2%. From measured target plane intensity distributions, overall illumination uniformity with tangentially focused beams is estimated to be approx. =5%. In 1984, a symmetric set of six beams was upconverted to 351-nm radiation using the polarization-mismatch scheme developed by Craxton. Monolithic cells of 20-cm clear aperture containing both frequency and doubler and tripler type II KDP crystals in index-matching propylene carbonate liquid were incorporated to output of six of the Omega beams with a full set of UV beam diagnostics

Dance Facilities.

Science.gov (United States)

Ashton, Dudley, Ed.; Irey, Charlotte, Ed.

This booklet represents an effort to assist teachers and administrators in the professional planning of dance facilities and equipment. Three chapters present the history of dance facilities, provide recommended dance facilities and equipment, and offer some adaptations of dance facilities and equipment, for elementary, secondary and college level…

Radiological Research Accelerator Facility. Progress report, April 1-November 30, 1986

International Nuclear Information System (INIS)

1986-07-01

The Radiological Research Accelerator Facility (RARAF) is based on a 4-MV Van de Graaff accelerator, which is used to generate a variety of well-characterized radiation beams for research in radiobiology and radiological physics. The experiments run at RARAF are described, and center on neutron dosimetry, mutagenesis, and neutron-induced oncogenic transformations as well as survival of exposed cells. Accelerator utilization, operation, and development of facilities are reviewed

Facilities inventory protection for nuclear facilities

International Nuclear Information System (INIS)

Schmitt, F.J.

1989-01-01

The fact that shut-down applications have been filed for nuclear power plants, suggests to have a scrutinizing look at the scopes of assessment and decision available to administrations and courts for the protection of facilities inventories relative to legal and constitutional requirements. The paper outlines the legal bases which need to be observed if purposeful calculation is to be ensured. Based on the different actual conditions and legal consequences, the author distinguishes between 1) the legal situation of facilities licenced already and 2) the legal situation of facilities under planning during the licencing stage. As indicated by the contents and restrictions of the pertinent provisions of the Atomic Energy Act and by the corresponding compensatory regulation, the object of the protection of facilities inventor in the legal position of the facility owner within the purview of the Atomic Energy Act, and the licensing proper. Art. 17 of the Atomic Energy Act indicates the legislators intent that, once issued, the licence will be the pivotal point for regulations aiming at protection and intervention. (orig./HSCH) [de

Alpha Decontamination and Disassembly Pilot Facility. Final report

International Nuclear Information System (INIS)

Daugherty, B.A.; Clark, H.E.

1985-04-01

The Alpha Decontamination and Disassembly (AD and D) Pilot Facility was built to develop and demonstrate a reference process for the decontamination and size reduction of noncombustible transuranic (TRU) waste. The goals of the reference process were to remove >99% of the surface contamination to the high-level waste tanks, and to achieve volume reduction factors greater than 15:1. Preliminary bench-scale decontamination work was accomplished at Savannah River Laboratory (SRL), establishing a reference decontamination process. Initially, the pilot facility did not achieve the decontamination goals. As the program continued, and modifications to the process were made, coupon analysis idicated that 99% of the surface contamination was removed to the high-level drain system. Prior to the AD and D Pilot Facility, no size reduction work had been done at SRL. Several other Department of Energy (DOE) facilities were experimenting with plasma arc torches for size reduction work. Their methods were employed in the AD and D hot cell with moderate success. The experimental work concluded with recommendations for further testing of other size reduction techniques. 11 figs., 6 tabs

New method for characterizing electron mediators in microbial systems using a thin-layer twin-working electrode cell.

Science.gov (United States)

Hassan, Md Mahamudul; Cheng, Ka Yu; Ho, Goen; Cord-Ruwisch, Ralf

2017-01-15

Microbial biofilms are significant ecosystems where the existence of redox gradients drive electron transfer often via soluble electron mediators. This study describes the use of two interfacing working electrodes (WEs) to simulate redox gradients within close proximity (250µm) for the detection and quantification of electron mediators. By using a common counter and reference electrode, the potentials of the two WEs were independently controlled to maintain a suitable "voltage window", which enabled simultaneous oxidation and reduction of electron mediators as evidenced by the concurrent anodic and cathodic currents, respectively. To validate the method, the electrochemical properties of different mediators (hexacyanoferrate, HCF, riboflavin, RF) were characterized by stepwise shifting the "voltage window" (ranging between 25 and 200mV) within a range of potentials after steady equilibrium current of both WEs was established. The resulting differences in electrical currents between the two WEs were recorded across a defined potential spectrum (between -1V and +0.5V vs. Ag/AgCl). Results indicated that the technique enabled identification (by the distinct peak locations at the potential scale) and quantification (by the peak of current) of the mediators for individual species as well as in an aqueous mixture. It enabled a precise determination of mid-potentials of the externally added mediators (HCF, RF) and mediators produced by pyocyanin-producing Pseudomonas aeruginosa (WACC 91) culture. The twin working electrode described is particularly suitable for studying mediator-dependent microbial electron transfer processes or simulating redox gradients as they exist in microbial biofilms. Copyright © 2016 Elsevier B.V. All rights reserved.

Proteolytic processing of connective tissue growth factor in normal ocular tissues and during corneal wound healing.

Science.gov (United States)

Robinson, Paulette M; Smith, Tyler S; Patel, Dilan; Dave, Meera; Lewin, Alfred S; Pi, Liya; Scott, Edward W; Tuli, Sonal S; Schultz, Gregory S

2012-12-13

Connective tissue growth factor (CTGF) is a fibrogenic cytokine that is up-regulated by TGF-β and mediates most key fibrotic actions of TGF-β, including stimulation of synthesis of extracellular matrix and differentiation of fibroblasts into myofibroblasts. This study addresses the role of proteolytic processing of CTGF in human corneal fibroblasts (HCF) stimulated with TGF-β, normal ocular tissues and wounded corneas. Proteolytic processing of CTGF in HCF cultures, normal animal eyes, and excimer laser wounded rat corneas were examined by Western blot. The identity of a 21-kDa band was determined by tandem mass spectrometry, and possible alternative splice variants of CTGF were assessed by 5' Rapid Amplification of cDNA Ends (RACE). HCF stimulated by TGF-β contained full length 38-kDa CTGF and fragments of 25, 21, 18, and 13 kDa, while conditioned medium contained full length 38- and a 21-kDa fragment of CTGF that contained the middle "hinge" region of CTGF. Fragmentation of recombinant CTGF incubated in HCF extracts was blocked by the aspartate protease inhibitor, pepstatin. Normal mouse, rat, and rabbit whole eyes and rabbit ocular tissues contained abundant amounts of C-terminal 25- and 21-kDa fragments and trace amounts of 38-kDa CTGF, although no alternative transcripts were detected. All forms of CTGF (38, 25, and 21 kDa) were detected during healing of excimer ablated rat corneas, peaking on day 11. Proteolytic processing of 38-kDa CTGF occurs during corneal wound healing, which may have important implications in regulation of corneal scar formation.

Influence of Casting Defects on S- N Fatigue Behavior of Ni-Al Bronze

Science.gov (United States)

Sarkar, Aritra; Chakrabarti, Abhishek; Nagesha, A.; Saravanan, T.; Arunmuthu, K.; Sandhya, R.; Philip, John; Mathew, M. D.; Jayakumar, T.

2015-02-01

Nickel-aluminum bronze (NAB) alloys have been used extensively in marine applications such as propellers, couplings, pump casings, and pump impellers due to their good mechanical properties such as tensile strength, creep resistance, and corrosion resistance. However, there have been several instances of in-service failure of the alloy due to high cycle fatigue (HCF). The present paper aims at characterizing the casting defects in this alloy through X-ray radiography and X-ray computed tomography into distinct defect groups having particular defect size and location. HCF tests were carried out on each defect group of as-cast NAB at room temperature by varying the mean stress. A significant decrease in the HCF life was observed with an increase in the tensile mean stress, irrespective of the defect size. Further, a considerable drop in the HCF life was observed with an increase in the size of defects and proximity of the defects to the surface. However, the surface proximity indicated by location of the defect in the sample was seen to override the influence of defect size and maximum cyclic stress. This leads to huge scatter in S- N curve. For a detailed quantitative analysis of defect size and location, an empirical model is developed which was able to minimize the scatter to a significant extent. Further, a concept of critical distance is proposed, beyond which the defect would not have a deleterious consequence on the fatigue behavior. Such an approach was found to be suitable for generating S- N curves for cast NAB.

A new energy-dispersive powder diffraction facility at the SRS

International Nuclear Information System (INIS)

Clark, S.M.

1996-01-01

A new energy-dispersive powder diffraction facility has been constructed on the 6 T wiggler beam line of the Daresbury Laboratory Synchrotron Radiation Source. This paper describes the facility, in particular the beam definition apparatus (front end), the detector positioning system (back end), a 10 000 kN loading frame and high pressure cell and the counting and control electronics. Some recent results are presented including a study of the compressibility of talc and the phase I→II transition of ammonium chloride. (orig.)

Facility effluent monitoring plan determinations for the 200 Area facilities

International Nuclear Information System (INIS)

Nickels, J.M.

1991-11-01

The following facility effluent monitoring plan determinations document the evaluations conducted for the Westinghouse Hanford Company 200 Area facilities (chemical processing, waste management, 222-S Laboratory, and laundry) on the Hanford Site in south central Washington State. These evaluations determined the need for facility effluent monitoring plans for the 200 Area facilities. The facility effluent monitoring plan determinations have been prepared in accordance with A Guide for Preparing Hanford Site Facility Effluent Monitoring Plans, WHC-EP-0438 (WHC 1991). The Plutonium/Uranium Extraction Plant and UO 3 facility effluent monitoring plan determinations were prepared by Los Alamos Technical Associates, Richland, Washington. The Plutonium Finishing Plant, Transuranic Waste Storage and Assay Facility, T Plant, Tank Farms, Low Level Burial Grounds, and 222-S Laboratory determinations were prepared by Science Applications International Corporation of Richland, Washington. The B Plant Facility Effluent Monitoring Plan Determination was prepared by ERCE Environmental Services of Richland, Washington

Supporting of some ferrocyanides on polyacrylonitrile (PAN) binding polymer and their application for cesium treatment

International Nuclear Information System (INIS)

Someda, H.H.; El Zahhar, A.A.; Shehata, M.K.; El-Naggar, H.A.

2001-01-01

Transition metal ferrocyanides were supported on polyacrylonitrile (PAN) as a binding polymer and were used for removal of radiocesium. The sorption capacity were determined for each sorbent and was found to be 1.22 and 0.65 meq/gm for KZnHCF-PAN and KCuHCF-PAN respectively. Different parameters affecting the sorption process were studied as chemical nature of the active solution, presence of competing ions and flow rate of feed solution. The regeneration of the used sorbent was studied using different solutions and also reusing the regenerated sorbent in other cycle up to four cycles (authors)

Positive ion irradiation facility

International Nuclear Information System (INIS)

Braby, L.A.

1985-01-01

Many questions about the mechanisms of the response of cells to ionizing radiation can best be investigated using monoenergetic heavy charged particle beams. Questions of the role of different types of damage in the LET effect, for example, are being answered by comparing repair kinetics for damage induced by electrons with that produced by helium ions. However, as the models become more sophicated, the differences between models can be detected only with more precise measurements, or by combining high- and low-LET irradiations in split-dose experiments. The design of the authors present cell irradiation beam line has limited the authors to irradiating cells in a partial vacuum. A new way to mount the dishes and bring the beam to the cells was required. Several means of irradiating cells in mylar-bottom dishes have been used at other laboratories. For example at the RARAF Facility, the dual ion experiments are done with the dish bottom serving as the beam exit window but the cells are in a partial vacuum to prevent breaking the window. These researchers have chosen instead to use the dish bottom as the beam window and to irradiate the entire dish in a single exposure. A special, very fast pumping system will be installed at the end of the beam line. This system will make it possible to irradiate cells within two minutes of installing them in the irradiation chamber. In this way, the interaction of electron and ion-induced damage in Chlamydomonas can be studied with time between doses as short as 5 minutes

Rationalization design on large equipment dismantling facility. The cell fire-extinguishing examination (3)

International Nuclear Information System (INIS)

Donomae, Yasushi; Matsumoto, Yoshihiro; Takita, Koji; Kikuchi, Yutaka; Katoh, Noriyoshi; Miyazaki, Hitoshi; Tanimoto, Ken-ichi

2002-07-01

In order to rationalize for Large Equipment Dismantling Facility (LEDF), the plan of removing vaporizer belong to Cell-fire-extinguishing-system was investigated. When a vaporizer is cut down, it is necessary to grasp a fire-extinguishing performance. The fire-extinguishing performance check examination by liquefaction carbon dioxide in the cell fire-extinguishing examination (I) was carried out in 1999 fiscal year. As the result, the good performance was obtained to polyethylene. But there was the deep-seated fire about a piece of wood. Then, the check items were carbon dioxide (CO2) concentration and CO2 concentration holding time for the deep-seated fire in the cell fire-extinguishing examination (III). The results were as follows; (1) By use of the combustion model in which a piece of wood and cotton were put is lit, temperature inside model, mass reduction, and combustion situation were examined. The model burned remarkably in 30∼60 min. The peak temperature rise to 680 degC (MAX), and attained smoldering after (ignition) 70 min. Moreover, in order to determine the generating conditions of a deep-seated fire, the situation of CO2 extinguishing after ignition by the time lag of 50∼90 min were examined. The model around ignition 50 minutes was the most difficult to extinguish, and it turned out that they are the conditions which were most suitable for the deep-seated fire examination model of an exam. (2) In order to decide on CO2 concentration and concentration holding time required for fire extinguishing of the deep-seated fire in LEDF, the fire-extinguishing performance was investigated by 40 ∼ 65% of CO2 concentration. Consequently, CO2 concentration required for deep-seated fire extinguishing was understood that 60% or more was required when safety was taken into consideration at 50% or more. Moreover, when it was 50% or more of CO2 concentration and the holding time of CO2 concentration was 180 minutes or more and 60% or more of CO2 concentration, it

Facilities & Leadership

Data.gov (United States)

Department of Veterans Affairs — The facilities web service provides VA facility information. The VA facilities locator is a feature that is available across the enterprise, on any webpage, for the...

Facility model for the Los Alamos Plutonium Facility

International Nuclear Information System (INIS)

Coulter, C.A.; Thomas, K.E.; Sohn, C.L.; Yarbro, T.F.; Hench, K.W.

1986-01-01

The Los Alamos Plutonium Facility contains more than sixty unit processes and handles a large variety of nuclear materials, including many forms of plutonium-bearing scrap. The management of the Plutonium Facility is supporting the development of a computer model of the facility as a means of effectively integrating the large amount of information required for material control, process planning, and facility development. The model is designed to provide a flexible, easily maintainable facility description that allows the faciltiy to be represented at any desired level of detail within a single modeling framework, and to do this using a model program and data files that can be read and understood by a technically qualified person without modeling experience. These characteristics were achieved by structuring the model so that all facility data is contained in data files, formulating the model in a simulation language that provides a flexible set of data structures and permits a near-English-language syntax, and using a description for unit processes that can represent either a true unit process or a major subsection of the facility. Use of the model is illustrated by applying it to two configurations of a fictitious nuclear material processing line

Development of a spent fuel management technology research and test facility

Energy Technology Data Exchange (ETDEWEB)

Park, S W; Noh, S K; Lee, J S. and others

1997-12-01

This study was intended to develop concept for a pilot-scale remote operation facility for longer term management of spent fuel and therefrom to provide technical requirement for later basic design of the facility. Main scope of work for the study was to revise the past (1990) conceptual design in functions, scale, hot cell layout, etc. based on user requirements. Technical reference was made to the PKA facility in Germany, through collaboration with appropriate partner, to elaborate the design and requirements. A simulator of the conceptual design was also developed by use of virtual reality technique by 3-D computer graphics for equipment and building. (author). 18 tabs., 39 figs

Engineering and technology in the deconstruction of nuclear materials production facilities

International Nuclear Information System (INIS)

Kingsley, R.S.; Reynolds, W.E.; Heffner, D.C.

1996-01-01

Technology and equipment exist to support nuclear facility deactivation, decontamination, and decommissioning. In reality, this statement is not surprising because the nuclear industry has been decontaminating and decommissioning production plants for decades as new generations of production technology were introduced. Since the 1950s, the Babcock and Wilcox Company (B ampersand W) has operated a number of nuclear materials processing facilities to manufacture nuclear fuel for the commercial power industry and the U.S. Navy. These manufacturing facilities included a mixed oxide (PuO 2 -UO 2 ) nuclear fuel manufacturing plant, low- and high-enriched uranium (HEU/LEU) chemical and fuel plants, and fuel assembly plants. In addition, B ampersand W designed and build a major nuclear research center in Lynchburg, Virginia, to support these nuclear fuel manufacturing activities and to conduct nuclear power research. These nuclear research facilities included two research reactors, a hot-cell complex for nuclear materials research, four critical experiment facilities, and a plutonium fuels research and development facility. This article describes the B ampersand W deactivation, decomtanimation, and decommisioning program

SP-100 reactor cell activation

International Nuclear Information System (INIS)

Wilcox, A.D.

1991-09-01

There are plans to test the SP-100 space reactor for 2 yr in the test facility shown in Figure 1. The vacuum vessel will be in the reactor experiment (RX) cell surrounded by an inert gas atmosphere. It is proposed that the reactor test cell could contain removable-water- shielding tanks to reduce the residual activation dose rates in the test cell after the tests are completed. This reduction will allow the facility to be considered for other uses after the SP-100 tests are completed. The radiation dose rates in the test cell were calculated for several configurations of water-shielding tanks to help evaluate this concept

Safety issues in urban transit facilities for hydrogen-fueled buses

International Nuclear Information System (INIS)

Hay, R.H.; Ducharme, P.

2004-01-01

'Full text:' The Canadian Transportation Fuel Cell Alliance (CTFCA), created by the Canadian Government as part of its 2000 Climate Change Action Plan, has commissioned MARCON-DDM's Hydrogen Intervention Team (HIT) to provide a roadmap for urban transit systems that wish to move to hydrogen fuel cell-powered bus fleets. HIT is currently in the process of gathering information from hydrogen technology providers, bus manufacturers, fuelling system providers and urban transit systems in Canada, the US and Europe. In September, HIT will be in a position to provide a hands-on perspective of the introduction of fuel-cell buses in the Canadian environment. Part of the process of adding hydrogen-fueled busses to urban transit systems involves phasing in the new technology to minimize the economic cost. This involves substituting hydrogen buses into the normal bus procurement life cycle and maximizing the use of existing facilities for garaging, maintenance and fueling. Using a schematic outline of an urban transit system, this presentation will outline the safety issues specific to hydrogen in such systems, particularly for garaging, maintenance and fueling components. It will then outline how safety of these component is addressed in current and proposed codes, standards and recommended practices. Based on these requirements the impact of the introduction of hydrogen-fueled buses on each component of the transit system will be addressed in terms of the adaptations of current facilities and practices or the requirements for new facilities and practices. (author)

PACCOM: A nuclear waste packaging facility cost model: Draft technical report

International Nuclear Information System (INIS)

Dippold, D.G.; Tzemos, S.; Smith, D.J.

1985-05-01

PACCOM is a computerized, parametric model used to estimate the capital, operating, and decommissioning costs of a variety of nuclear waste packaging facility configurations. The model is based upon a modular waste packaging facility concept from which functional components of the overall facility have been identified and their design and costs related to various parameters such as waste type, waste throughput, and the number of operational shifts employed. The model may be used to either estimate the cost of a particular waste packaging facility configuration or to explore the cost tradeoff between plant capital and labor. That is, one may use the model to search for the particular facility sizes and associated cost which when coupled with a particular number of shifts, and thus staffing level, leads to the lowest overall total cost. The functional components which the model considers include hot cells and their supporting facilities, transportation, cask handling facilities, transuranic waste handling facilities, and administrative facilities such as warehouses, security buildings, maintenance buildings, etc. The cost of each of these functional components is related either directly or indirectly to the various independent design parameters. Staffing by shift is reported into direct and indirect support labor. These staffing levels are in turn related to the waste type, waste throughput, etc. 2 refs., 11 figs., 3 tabs

Facilities Performance Indicators Report 2013-14: Tracking Your Facilities Vital Signs

Science.gov (United States)

APPA: Association of Higher Education Facilities Officers, 2015

2015-01-01

This paper features an expanded Web-based "Facilities Performance Indicators (FPI) Report." The purpose of APPA: Association of Higher Education Facilities Officers (APPA's) Facilities Performance Indicators is to provide a representative set of statistics about facilities in educational institutions. "The Facilities Performance…

Defense waste processing facility radioactive operations. Part 1 - operating experience

International Nuclear Information System (INIS)

Little, D.B.; Gee, J.T.; Barnes, W.M.

1997-01-01

The Savannah River Site's Defense Waste Processing Facility (DWPF) near Aiken, SC is the nation's first and the world's largest vitrification facility. Following a ten year construction program and a 3 year non-radioactive test program, DWPF began radioactive operations in March 1996. This paper presents the results of the first 9 months of radioactive operations. Topics include: operations of the remote processing equipment reliability, and decontamination facilities for the remote processing equipment. Key equipment discussed includes process pumps, telerobotic manipulators, infrared camera, Holledge trademark level gauges and in-cell (remote) cranes. Information is presented regarding equipment at the conclusion of the DWPF test program it also discussed, with special emphasis on agitator blades and cooling/heating coil wear. 3 refs., 4 figs

Stereotactic body radiotherapy and treatment at a high volume facility is associated with improved survival in patients with inoperable stage I non-small cell lung cancer

International Nuclear Information System (INIS)

Koshy, Matthew; Malik, Renuka; Mahmood, Usama; Husain, Zain; Sher, David J.

2015-01-01

Background: This study examined the comparative effectiveness of no treatment (NoTx), conventional fractionated radiotherapy (ConvRT), and stereotactic body radiotherapy (SBRT) in patients with inoperable stage I non-small cell lung cancer. This population based cohort also allowed us to examine what facility level characteristics contributed to improved outcomes. Methods: We included patients in the National Cancer Database from 2003 to 2006 with T1-T2N0M0 inoperable lung cancer (n = 13,036). Overall survival (OS) was estimated using Kaplan–Meier methods and Cox proportional hazard regression. Results: The median follow up was 68 months (interquartile range: 35–83 months) in surviving patients. Among the cohort, 52% received NoTx, 41% received ConvRT and 6% received SBRT. The 3-year OS was 28% for NoTx, 36% for ConvRT radiotherapy, and 48% for the SBRT cohort (p < 0.0001). On multivariate analysis, the hazard ratio for SBRT and ConvRT were 0.67 and 0.77, respectively, as compared to NoTx (1.0 ref) (p < 0.0001). Patients treated at a high volume facility vs. low volume facility had a hazard ratio of 0.94 vs. 1.0 (p = 0.01). Conclusions: Patients with early stage inoperable lung cancer treated with SBRT and at a high volume facility had a survival benefit compared to patients treated with ConvRT or NoTx or to those treated at a low volume facility

Communication grounding facility

International Nuclear Information System (INIS)

Lee, Gye Seong

1998-06-01

It is about communication grounding facility, which is made up twelve chapters. It includes general grounding with purpose, materials thermal insulating material, construction of grounding, super strength grounding method, grounding facility with grounding way and building of insulating, switched grounding with No. 1A and LCR, grounding facility of transmission line, wireless facility grounding, grounding facility in wireless base station, grounding of power facility, grounding low-tenton interior power wire, communication facility of railroad, install of arrester in apartment and house, install of arrester on introduction and earth conductivity and measurement with introduction and grounding resistance.

Proposed Californium-252 User Facility for Neutron Science at Oak Ridge National Laboratory

International Nuclear Information System (INIS)

Martin, R.C.; Laxson, R.R.; Knauer, J.B.

1996-01-01

The Radiochemical Engineering Development Center (REDC) at ORNL has petitioned to establish a Californium-252 User Facility for Neutron Science for academic, industrial, and governmental researchers. The REDC Californium Facility (CF) stores the national inventory of sealed 252 Cf neutron source for university and research loans. Within the CF, the 252 Cf storage pool and two uncontaminated hot cells currently in service for the Californium Program will form the physical basis for the User Facility. Relevant applications include dosimetry and experiments for neutron tumor therapy; fast and thermal neutron activation analysis of materials; experimental configurations for prompt gamma neutron activation analysis; neutron shielding and material damage studies; and hardness testing of radiation detectors, cameras, and electronics. A formal User Facility simplifies working arrangements and agreements between US DOE facilities, academia, and commercial interests

An improved out-cell to in-cell rapid transfer system at the HFEF-south

International Nuclear Information System (INIS)

Bacca, J.P.; Sherman, E.K.

1990-01-01

The Argonne National Laboratory (ANL) Hot Fuel Examination Facility-South (HFEF-S), located at the ANL-West site of the Idaho National Engineering Laboratory, is currently undergoing extensive refurbishment and modifications in preparation for its use, beginning in 1991, in demonstrating remote recycling of fast reactor, metal-alloy fuel as part of the US Department of Energy liquid-metal reactor, Integral Fast Reactor (IFR) program. Included in these improvements to HFEF-S is a new, small-item, rapid transfer system (RTS). When installed, this system will enable the rapid transfer of small items from the hot-cell exterior into the argon cell (argon-gas atmosphere) of the facility without necessitating the use of time-consuming and laborious procedures. The new RTS will also provide another important function associated with HFEF-S hot-cell operation in the IFR Fuel Recycle Program; namely, the rapid insertion of clean, radioactive contamination-measuring smear paper specimens into the hot cells for area surveys, and the expedited removal of these contaminated (including alpha as well as beta/gamma contamination) smears from the argon cell for transfer to an adjacent health physics field laboratory in the facility for nuclear contamination/radiation counting

Impacts of transportation on a test and evaluation facility for nuclear waste disposal: a systems analysis

International Nuclear Information System (INIS)

Varadarajan, R.V.; Peterson, R.W.; Joy, D.S.; Gibson, S.M.

1983-01-01

An essential element of the Test and Evaluation Facility (TEF) is a waste packaging facility capable of producing a small number Test and Evaluation Facility of packages consisting of several different waste forms. The study envisions three scenarios for such a packaging facility: (1) modify an existing hot cell facility such as the Engine Maintenance Assembly and Disassembly (EMAD) facility at the Nevada Test Site so that it can serve as a packaging facility for the TEF. This scenario is referred to as the EMAD Option. (2) Build a new generic packaging facility (GPF) at the site of the TEF. In other words, colocate the GPF and the TEF. This scenario is referred to as the GPF Option, and (3) utilize the EMAD facility in conjunction with a colocated GPF (of minimal size and scope) at the TEF. This scenario is referred to as the Split Option. The results of the system study clearly bring out the fact that transportation has a significant impact on the selection and siting of the waste packaging facility. Preliminary conclusions, subject to the assumptions of the study, include the following: (1) regardless of the waste form, the GPF option is preferable to the other two in minimizing both transportation costs and logistical problems, (2) for any given scenario and choice of waste forms, there exists a candidate TEF location for which the transportation costs are at a minimum compared to the other locations, (3) in spite of the increased transportation costs and logistical complexity, the study shows that the overall system costs favor modification of an existing hot cell facility for the particular case considered

Facility effluent monitoring plan for the 327 Facility

International Nuclear Information System (INIS)

1994-11-01

The 327 Facility [Post-Irradiation Testing Laboratory] provides office and laboratory space for Pacific Northwest Laboratory (PNL) scientific and engineering staff conducting multidisciplinary research in the areas of post-irradiated fuels and structural materials. The facility is designed to accommodate the use of radioactive and hazardous materials in the conduct of these activities. This report summarizes the airborne emissions and liquid effluents and the results of the Facility Effluent Monitoring Plan (FEMP) determination for the facility. The complete monitoring plan includes characterization of effluent streams, monitoring/sampling design criteria, a description of the monitoring systems and sample analysis, and quality assurance requirements

Site characterization of ORNL D ampersand D facilities

International Nuclear Information System (INIS)

Kelsey, A.P.; Mandry, G.J.; Haghighi, M.H.

1994-01-01

Site characterization for decontamination and decommissioning (D ampersand D) planning purposes was done for two surplus facilities at Oak Ridge National Laboratory (ORNL) in late 1993 and early 1994. This site characterization includes measurements of radiological and chemical contaminants, assessment of general structural conditions, and investigation of unknown conditions within the buildings. It will serve as input to decisions on D ampersand D engineering, D ampersand D task sequences, radiological and contamination control, and waste management. This paper presents the methods used to investigate these facilities and discusses the preliminary results as they apply to D ampersand D planning. Investigation methods include gross alpha, beta, and gamma surveys; directional gamma surveys; gamma spectroscopy; concrete coring; photography; and collection of soil and miscellaneous samples that are analyzed for radiological and chemical contaminants. Data will be analyzed using radiological models to sort sources and estimate exposure rates and waste volumes due to D ampersand D. The former Waste Evaporator Facility (WEF), consisting of two concrete cells and an operating gallery, once contained a liquid radwaste evaporator. Subsequently it was used for an incinerator experiment and as a dressing area for remediation work on an adjacent tank farm. The building has been partially decontaminated. Figure 1 is a photograph of the WEF. The Fission Product Pilot Plant (FPPP) is a small concrete building containing two cells. It was used to extract isotopes of ruthenium, strontium, cesium, cerium, and other elements from liquid waste. This facility is highly contaminated. In 1960 all doors into FPPP were sealed with concrete block and mortar, and concrete block shielding was added to the external walls making them up to five feet thick. Prior to this study, almost nothing was known about the interior of this building

Technology of mirror machines: LLL facilities for magnetic mirror fusion experiments

International Nuclear Information System (INIS)

Batzer, T.H.

1977-01-01

Significant progress in plasma confinement and temperature has been achieved in the 2XIIB facility at Livermore. These encouraging results, and their theoretical corroboration, have provided a firm basis for the design of a new generation of magnetic mirror experiments, adding support to the mirror concept of a fusion reactor. Two new mirror experiments have been proposed to succeed the currently operating 2XIIB facility. The first of these called TMX (Tandem Mirror Experiment) has been approved and is currently under construction. TMX is designed to utilize the intrinsic positive plasma potential of two strong, and relatively small, minimum B mirror cells to enhance the confinement of a much larger, magnetically weaker, centrally-located mirror cell. The second facility, MFTF (Mirror Fusion Test Facility), is currently in preliminary design with line item approval anticipated for FY 78. MFTF is designed primarily to exploit the experimental and theoretical results derived from 2XIIB. Beyond that, MFTF will develop the technology for the transition from the present small mirror experiments to large steady-state devices such as the mirror FERF/FTR. The sheer magnitude of the plasma volume, magnetic field, neutral beam power, and vacuum pumping capacity, particularly in the case of MFTF, has placed new and exciting demands on engineering technology. An engineering overview of MFTF, TMX, and associated MFE activities at Livermore will be presented

Major facility overhauls at LAMPF

International Nuclear Information System (INIS)

Grisham, D.L.; Lambert, J.E.; Sommer, W.F. Jr.

1985-01-01

The Clinton P. Anderson Meson Physics Facility (LAMPF) is a linear proton accelerator designed to operate at 800 MeV and 1.0 mA. It has been operating at power levels above 200 microamperes since February of 1976 and now routinely operates near the design level. This paper outlines the problems encountered with the original target cell components, the repairs required since 1976, and specifically details the steps involved in the complete replacement of the vital target cell components. These components include target boxes, collimators, main beam line magnets, and the front-end magnets of the secondary beam lines. The A-2 target cell was replaced in the spring of 1983 and the A-1 target cell was replaced in the spring of 1984. Both have operated satisfactorily since their completion, with only minor difficulties. The overhaul and total component replacement in the beam stop area (A-6) was completed in early May 1985 and has just been placed in operation. The upgrade, in addition to the replacement of the beam stop and the vacuum-to-air window with state-of-the-art designs, provides a greatly increased capability of both proton and neutron irradiation of materials

Considerations in setting up and planning a graft processing facility.

Science.gov (United States)

Koh, Mickey B C

2017-12-01

The graft processing facility forms one of the core components of a clinical haematopoietic stem cell transplant program. The quality of a graft is instrumental in leading to consistent and reproducible outcomes of engraftment and other parameters. As such, meticulous planning and consideration is required and will include core elements including physical design and clinical correlates. The successful running of such a facility depends on an overarching quality program and adherence to local and international regulatory guidelines. Copyright © 2017 King Faisal Specialist Hospital & Research Centre. Published by Elsevier B.V. All rights reserved.

Shielding calculations for the Intense Neutron Source Facility. Final report

International Nuclear Information System (INIS)

Battat, M.E.; Henninger, R.J.; Macdonald, J.L.; Dudziak, D.J.

1978-06-01

Results of shielding calculations for the Intnse Neutron Source (INS) facility are presented. The INS facility is designed to house two sources, each of which will produce D--T neutrons with intensities in the range from 1 to 3 x 10 15 n/s on a continuous basis. Topics covered include the design of the biological shield, use of two-dimensional discrete-ordinates results to specify the source terms for a Monte Carlo skyshine calculation, air activation, and dose rates in the source cell (after shutdown) due to activation of the biological shield

Development of Optimized Core Design and Analysis Methods for High Power Density BWRs

Science.gov (United States)

Shirvan, Koroush

temperature was kept the same for the BWR-HD and ABWR which resulted in 4 °K cooler core inlet temperature for the BWR-HD given that its feedwater makes up a larger fraction of total core flow. The stability analysis using the STAB and S3K codes showed satisfactory results for the hot channel, coupled regional out-of-phase and coupled core-wide in-phase modes. A RELAPS model of the ABWR system was constructed and applied to six transients for the BWR-HD and ABWR. The 6MCPRs during all the transients were found to be equal or less for the new design and the core remained covered for both. The lower void coefficient along with smaller core volume proved to be advantages for the simulated transients. Helical Cruciform Fuel (HCF) rods were proposed in prior MIT studies to enhance the fuel surface to volume ratio. In this work, higher fidelity models (e.g. CFD instead of subchannel methods for the hydraulic behaviour) are used to investigate the resolution needed for accurate assessment of the HCF design. For neutronics, conserving the fuel area of cylindrical rods results in a different reactivity level with a lower void coefficient for the HCF design. In single-phase flow, for which experimental results existed, the friction factor is found to be sensitive to HCF geometry and cannot be calculated using current empirical models. A new approach for analysis of flow crisis conditions for HCF rods in the context of Departure from Nucleate Boiling (DNB) and dryout using the two phase interface tracking method was proposed and initial results are presented. It is shown that the twist of the HCF rods promotes detachment of a vapour bubble along the elbows which indicates no possibility for an early DNB for the HCF rods and in fact a potential for a higher DNB heat flux. Under annular flow conditions, it was found that the twist suppressed the liquid film thickness on the HCF rods, at the locations of the highest heat flux, which increases the possibility of reaching early dryout. It

Concentrated fed-batch cell culture increases manufacturing capacity without additional volumetric capacity.

Science.gov (United States)

Yang, William C; Minkler, Daniel F; Kshirsagar, Rashmi; Ryll, Thomas; Huang, Yao-Ming

2016-01-10

Biomanufacturing factories of the future are transitioning from large, single-product facilities toward smaller, multi-product, flexible facilities. Flexible capacity allows companies to adapt to ever-changing pipeline and market demands. Concentrated fed-batch (CFB) cell culture enables flexible manufacturing capacity with limited volumetric capacity; it intensifies cell culture titers such that the output of a smaller facility can rival that of a larger facility. We tested this hypothesis at bench scale by developing a feeding strategy for CFB and applying it to two cell lines. CFB improved cell line A output by 105% and cell line B output by 70% compared to traditional fed-batch (TFB) processes. CFB did not greatly change cell line A product quality, but it improved cell line B charge heterogeneity, suggesting that CFB has both process and product quality benefits. We projected CFB output gains in the context of a 2000-L small-scale facility, but the output was lower than that of a 15,000-L large-scale TFB facility. CFB's high cell mass also complicated operations, eroded volumetric productivity, and showed our current processes require significant improvements in specific productivity in order to realize their full potential and savings in manufacturing. Thus, improving specific productivity can resolve CFB's cost, scale-up, and operability challenges. Copyright © 2015 Elsevier B.V. All rights reserved.

Patient perspectives on the promptness and quality of care of road traffic incident victims in Peru: a cross-sectional, active surveillance study

Science.gov (United States)

Miranda, J Jaime

2013-01-01

Background: Road injuries are the second-leading cause of disease and injury in the Andean region of South America. Adequate management of road traffic crash victims is important to prevent and reduce deaths and serious long-term injuries. Objective: To evaluate the promptness of health care services provided to those injured in road traffic incidents (RTIs) and the satisfaction with those services during the pre-hospital and hospital periods. Methods: We conducted a cross-sectional study with active surveillance to recruit participants in emergency departments at eight health care facilities in three Peruvian cities: a large metropolitan city (Lima) and two provincial cities (an urban center in the southern Andes and an urban center in the rainforest region), between August and September 2009. The main outcomes of interest were promptness of care, measured by time between injury and each service offered, as well as patient satisfaction measured by the Service Quality (SERVQUAL) survey. We explored the association between outcomes and city, type of health care facility (HCF), and type of provider. Results: We recruited 644 adults seeking care for RTIs. This active surveillance strategy yielded 34% more events than anticipated, suggesting under-reporting in traditional registries. Median response time between a RTI and any care at a HCF was 33 minutes overall and only 62% of participants received professional care during the initial “golden” hour after the RTI. After adjustment for various factors, there was strong evidence of higher global dissatisfaction levels among those receiving care at public HCFs compared to private ones (odds ratio (OR) 5.05, 95% confidence interval (CI) 1.88-13.54). This difference was not observed when provincial sites were compared to Lima (OR 1.41, 95% CI 0.42-4.70). Conclusions: Response time to RTIs was adequate overall, though a large proportion of RTI victims could have received more prompt care. Overall, dissatisfaction was

Air Quality Facilities

Data.gov (United States)

Iowa State University GIS Support and Research Facility — Facilities with operating permits for Title V of the Federal Clean Air Act, as well as facilities required to submit an air emissions inventory, and other facilities...

Facilities Performance Indicators Report, 2004-05. Facilities Core Data Survey

Science.gov (United States)

Glazner, Steve, Ed.

2006-01-01

The purpose of "Facilities Performance Indicators" is to provide a representative set of statistics about facilities in educational institutions. The second iteration of the web-based Facilities Core Data Survey was posted and available to facilities professionals at more than 3,000 institutions in the Fall of 2005. The website offered a printed…

Conceptual design report for the spent fuel management technology research and test (SMATER) facility

Energy Technology Data Exchange (ETDEWEB)

Park, S W; Ro, S G; Lee, J S; Min, D K; Shin, Y J [Korea Atomic Energy Research Institute, Taejon (Korea)

1998-10-01

This study was intended to develop concept for a pilot-scale remote operation facility for longer term management of spent fuel and therefrom to provide technical requirement for later basic design of the facility. Main scope of work for the study was to revise the past (1990) conceptual design in functions, scale, hot cell layout etc. based on user requirements. Technical reference was made to the PKA facility in Germany, through collaboration with appropriate partner, to elaborate the design and requirements. The study was focused on establishing design criteria and conceptual design of the SMATER facility. The results of this study should be an essential and useful basis upon optimization for further work to basic design of the facility. (author). 17 figs., 12 tabs.

High-risk facilities. Emergency management in nuclear, chemical and hazardous waste facilities

International Nuclear Information System (INIS)

Kloepfer, Michael

2012-01-01

The book on emergency management in high-risk facilities covers the following topics: Change in the nuclear policy, risk management of high-risk facilities as a constitutional problem - emergency management in nuclear facilities, operational mechanisms of risk control in nuclear facilities, regulatory surveillance responsibilities for nuclear facilities, operational mechanism of the risk control in chemical plants, regulatory surveillance responsibilities for chemical facilities, operational mechanisms of the risk control in hazardous waste facilities, regulatory surveillance responsibilities for hazardous waste facilities, civil law consequences in case of accidents in high-risk facilities, criminal prosecution in case of accidents in high-risk facilities, safety margins as site risk for emission protection facilities, national emergency management - strategic emergency management structures, warning and self-protection of the public in case of CBRN hazards including aspects of the psych-social emergency management.

Cryogenic technology review of cold neutron source facility for localization

Energy Technology Data Exchange (ETDEWEB)

Lee, Hun Cheol; Park, D. S.; Moon, H. M.; Soon, Y. P. [Daesung Cryogenic Research Institute, Ansan (Korea); Kim, J. H. [United Pacific Technology, Inc., Ansan (Korea)

1998-02-01

This Research is performed to localize the cold neutron source(CNS) facility in HANARO and the report consists of two parts. In PART I, the local and foreign technology for CNS facility is investigated and examined. In PART II, safety and licensing are investigated. CNS facility consists of cryogenic and warm part. Cryogenic part includes a helium refrigerator, vacuum insulated pipes, condenser, cryogenic fluid tube and moderator cell. Warm part includes moderator gas control, vacuum equipment, process monitoring system. Warm part is at high level as a result of the development of semiconductor industries and can be localized. However, even though cryogenic technology is expected to play a important role in developing the 21st century's cutting technology, it lacks of specialists and the research facility since the domestic market is small and the research institutes and government do not recognize the importance. Therefore, it takes a long research time in order to localize the facility. The safety standard of reactor for hydrogen gas in domestic nuclear power regulations is compared with that of the foreign countries, and the licensing method for installation of CNS facility is examined. The system failure and its influence are also analyzed. 23 refs., 59 figs., 26 tabs. (Author)

Facile moldless fabrication of disk-shaped and reed blood cell-like microparticles using photopolymerization of tripropylene glycol diacrylate

International Nuclear Information System (INIS)

Choi, Jongchul; Won, June; Song, Simon

2014-01-01

A facile method for the moldless fabrication of 2- or 3-dimensional microparticles is proposed by using a photopolymerization technique. Using only a monomer solution of tripropylene glycol diacrylate, a film mask and standard UV lithography equipment, we were able to fabricate microparticles of various shapes, such as disks, dimpled disks similar in shape to red blood cells, and slender gourd shapes, unlike previous moldless fabrication techniques requiring expensive and/or sophisticated equipment. The simple method could produce more than one million particles in a single batch, indicating that it can be applied to the mass production of polymer microparticles. Analyses of scanning electron micrographs and optical micrographs of the microparticles indicated that their size distribution was highly monodisperse. Detailed fabrication processes and statistics on the microparticle sizes are given in this paper. (technical note)

Nuclear facilities

International Nuclear Information System (INIS)

Anon.

2000-01-01

Here is given the decree (2000-1065) of the 25. of October 2000 reporting the publication of the convention between the Government of the French Republic and the CERN concerning the safety of the LHC (Large Hadron Collider) and the SPS (Proton Supersynchrotron) facilities, signed in Geneva on July 11, 2000. By this convention, the CERN undertakes to ensure the safety of the LHC and SPS facilities and those of the operations of the LEP decommissioning. The French legislation and regulations on basic nuclear facilities (concerning more particularly the protection against ionizing radiations, the protection of the environment and the safety of facilities) and those which could be decided later on apply to the LHC, SPS and auxiliary facilities. (O.M.)

Facility effluent monitoring plan for 242-A Evaporator facility

International Nuclear Information System (INIS)

Crummel, G.M.; Gustavson, R.D.

1993-03-01

A facility effluent monitoring plan is required by the US Department of Energy in DOE Order 5400.1* for any operations that involve hazardous materials and radioactive substances that could affect employee or public safety or the environment. A facility effluent monitoring plan determination was performed during Calendar Year 1991 and the evaluation showed the need for a facility effluent monitoring plan. This document is prepared using the specific guidelines identified in A Guide for Preparing Hanford Site Facility effluent Monitoring Plans, WHC-EP-0438-1**. This facility effluent monitoring plan assesses effluent monitoring systems and evaluates whether they are adequate to ensure the public health and safety as specified in applicable federal, state, and local requirements

Impurity levels and fatigue lives of pseudoelastic NiTi shape memory alloys

International Nuclear Information System (INIS)

Rahim, M.; Frenzel, J.; Frotscher, M.; Pfetzing-Micklich, J.; Steegmüller, R.; Wohlschlögel, M.; Mughrabi, H.; Eggeler, G.

2013-01-01

In the present work we show how different oxygen (O) and carbon (C) levels affect fatigue lives of pseudoelastic NiTi shape memory alloys. We compare three alloys, one with an ultrahigh purity and two which contain the maximum accepted levels of C and O. We use bending rotation fatigue (up to cycle numbers >10 8 ) and scanning electron microscopy (for investigating microstructural details of crack initiation and growth) to study fatigue behavior. High cycle fatigue (HCF) life is governed by the number of cycles required for crack initiation. In the low cycle fatigue (LCF) regime, the high-purity alloy outperforms the materials with higher number densities of carbides and oxides. In the HCF regime, on the other hand, the high-purity and C-containing alloys show higher fatigue lives than the alloy with oxide particles. There is high experimental scatter in the HCF regime where fatigue cracks preferentially nucleate at particle/void assemblies (PVAs) which form during processing. Cyclic crack growth follows the Paris law and does not depend on impurity levels. The results presented in the present work contribute to a better understanding of structural fatigue of pseudoelastic NiTi shape memory alloys

Copper hexacyanoferrate functionalized single-walled carbon nano-tubes for selective cesium extraction

International Nuclear Information System (INIS)

Draouil, H.; Alvarez, L.; Bantignies, J.L.; Causse, J.; Cambedouzou, J.; Flaud, V.; Zaibi, M.A.; Oueslati, M.

2017-01-01

Single-walled carbon nano-tubes (SWCNTs) are functionalized with copper hexacyanoferrate (CuHCF) nanoparticles to prepare solid substrates for sorption of cesium ions (Cs + ) from liquid outflows. The high mechanical resistance and large electrical conductivity of SWCNTs are associated with the ability of CuHCF nanoparticles to selectively complex Cs + ions in order to achieve membrane-like buckypapers presenting high loading capacity of cesium. The materials are thoroughly characterized using electron microscopy, Raman scattering, X-ray photoelectron spectroscopy and thermogravimetric analyses. Cs sorption isotherms are plotted after having measured the Cs + concentration by liquid phase ionic chromatography in the solution before and after exposure to the materials. It is found that the total sorption capacity of the material reaches 230 mg.g -1 , and that about one third of the sorbed Cs (80 mg.g -1 ) is selectively complexed in the CuHCF nanoparticles grafted on SWCNTs. The quantification of Cs + ions on different sorption sites is made for the first time, and the high sorption rates open interesting outlooks in the integration of such materials in devices for the controlled sorption and desorption of these ions. (authors)

North Slope, Alaska ESI: FACILITY (Facility Points)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This data set contains data for oil field facilities for the North Slope of Alaska. Vector points in this data set represent oil field facility locations. This data...

Fast Flux Test Facility: the first three years, 1982-1985

International Nuclear Information System (INIS)

1985-01-01

General information is provided concerning the Fast Flux Test Facility. Topics discussed include: mission and major accomplishments; background information; major construction milestones; acceptance testing; plant performance; plant operation; fuel performance; interim examination and maintenance cell; environmental effects; and future plans for the FFTF

Waste Encapsulation and Storage Facility (WESF) Interim Status Closure Plan

International Nuclear Information System (INIS)

SIMMONS, F.M.

2000-01-01

This document describes the planned activities and performance standards for closing the Waste Encapsulation and Storage Facility (WESF). WESF is located within the 225B Facility in the 200 East Area on the Hanford Facility. Although this document is prepared based on Title 40 Code of Federal Regulations (CFR), Part 265, Subpart G requirements, closure of the storage unit will comply with Washington Administrative Code (WAC) 173-303-610 regulations pursuant to Section 5.3 of the Hanford Federal Facility Agreement and Consent Order (Tri-Party Agreement) Action Plan (Ecology et al. 1996). Because the intention is to clean close WESF, postclosure activities are not applicable to this interim status closure plan. To clean close the storage unit, it will be demonstrated that dangerous waste has not been left onsite at levels above the closure performance standard for removal and decontamination. If it is determined that clean closure is not possible or environmentally is impracticable, the interim status closure plan will be modified to address required postclosure activities. WESF stores cesium and strontium encapsulated salts. The encapsulated salts are stored in the pool cells or process cells located within 225B Facility. The dangerous waste is contained within a double containment system to preclude spills to the environment. In the unlikely event that a waste spill does occur outside the capsules, operating methods and administrative controls require that waste spills be cleaned up promptly and completely, and a notation made in the operating record. Because dangerous waste does not include source, special nuclear, and by-product material components of mixed waste, radionuclides are not within the scope of this documentation. The information on radionuclides is provided only for general knowledge

The Continuous Electron Beam Accelerator Facility

International Nuclear Information System (INIS)

Grunder, H.A.; Bisognano, J.J.; Diamond, W.I.; Hartline, B.K.; Leemann, C.W.; Mougey, J.; Sundelin, R.M.; York, R.C.

1987-01-01

On February 13, 1987, construction started on the Continuous Electron Beam Accelerator Facility - a 4-GeV, 200-μA, continuous beam, electron accelerator facility designed for nuclear physics research. The machine has a racetrack configuration with two antiparallel, 500-MeV, superconducting linac segments connected by beam lines to allow four passes of recirculation. The accelerating structure consists of 1500-MHz, five-cell niobium cavities developed at Cornell University. A liquid helium cryogenic system cools the cavities to an operating temperature of 2 K. Beam extraction after any three of the four passes allows simultaneous delivery of up to three beams of independently variable currents and different, but correlated, energies to the three experimental areas. Beam breakup thresholds exceed the design current by nearly two orders of magnitude. Project completion and the start of physics operations are scheduled for 1993. The total estimated cost is $255 million

26 CFR 1.142(a)(5)-1 - Exempt facility bonds: Sewage facilities.

Science.gov (United States)

2010-04-01

... 26 Internal Revenue 2 2010-04-01 2010-04-01 false Exempt facility bonds: Sewage facilities. 1.142... Bonds § 1.142(a)(5)-1 Exempt facility bonds: Sewage facilities. (a) In general. Under section 103(a), a... in section 142(a) is a sewage facility. This section defines the term sewage facility for purposes of...

Facility transition instruction

International Nuclear Information System (INIS)

Morton, M.R.

1997-01-01

The Bechtel Hanford, Inc. facility transition instruction was initiated in response to the need for a common, streamlined process for facility transitions and to capture the knowledge and experience that has accumulated over the last few years. The instruction serves as an educational resource and defines the process for transitioning facilities to long-term surveillance and maintenance (S and M). Generally, these facilities do not have identified operations missions and must be transitioned from operational status to a safe and stable configuration for long-term S and M. The instruction can be applied to a wide range of facilities--from process canyon complexes like the Plutonium Uranium Extraction Facility or B Plant, to stand-alone, lower hazard facilities like the 242B/BL facility. The facility transition process is implemented (under the direction of the US Department of Energy, Richland Operations Office [RL] Assistant Manager-Environmental) by Bechtel Hanford, Inc. management, with input and interaction with the appropriate RL division and Hanford site contractors as noted in the instruction. The application of the steps identified herein and the early participation of all organizations involved are expected to provide a cost-effective, safe, and smooth transition from operational status to deactivation and S and M for a wide range of Hanford Site facilities

Scope and dissolution studies and characterization of irradiated nuclear fuel in Atalante Hot Cell Facilities (abstract and presentation slides)

Energy Technology Data Exchange (ETDEWEB)

Dancausse, Jean-Philippe; Reynier Tronche, Nathalie; Ferlay, Gilles; Herlet, Nathalie; Eysseric, Cathrine; Esbelin, Eric

2005-01-01

Since 1999, several studies on nuclear fuels were realised in C11/C12 Atalante Hot Cell. This paper presents firstly an overview of the apparatus used for fuel dissolution and characterisation like reactor design, gas trapping flask and solid/liquid separation. Then, the general methodology is described as a function of fuel, temperature, reagents, showing for each step, the reachable experimental data: Dissolution rate, chemical and radiochemical fuel composition including volatile LLRN, insoluble mass, composition, morphology, cladding chemical, radiochemical and physical characterisation using SIMS (made in Cadarache/LECA facilities), MEB. To conclude, some of the obtained results on 129I and 14C composition of oxide fuels, rate of dissolution and first results on dissolution studies of RERTR UMo fuel will be detailed. (Author)

Safety analysis of DUPIC fuel development facility

International Nuclear Information System (INIS)

Lee, H. H.; Park, J. J.; Shin, J. M.; Yang, M. S.; Baek, S. Y.; Ahn, J. Y.

2001-01-01

Various experimental facilities are necessary in order to perform experimental verification for development of DUPIC fuel fabrication technology. In special, since highly radioactive material such as spent PWR fuel is used for this experiment, DUPIC fuel fabrication has to be performed in hot cell by remote handling. Therefore, it should be provided with proper engineering requirement and safety. M6 hot cell of IMEF which is to used for DUPIC fuel fabrication experiment was constructed as an α-γ hot cell for material examination of small amount of high-burnup fuel. The characteristics and amount of spent fuel for DUPIC fuel fabrication experiment will be different from the original design criteria. Therefore, the increased amount of spent fuel and different characteristics of experiment result in not only change of shielding and enviornmental evaluation results but new requirement of nuclear criticality evaluation. Therefore, this study includes evaluation of shielding, environmental effect and nuclear criticality in case that IMEF M6 hot cell is used for DUPIC fuel fabrication

Facilities Performance Indicators Report 2012-13: Tracking Your Facilities Vital Signs

Science.gov (United States)

APPA: Association of Higher Education Facilities Officers, 2014

2014-01-01

This paper features an expanded Web-based "Facilities Performance Indicators (FPI) Report." The purpose of APPA's Facilities Performance Indicators is to provide a representative set of statistics about facilities in educational institutions. "The Facilities Performance Indicators Report" is designed for survey…

Preliminary safety evaluation of a commercial-scale krypton-85 encapsulation facility

International Nuclear Information System (INIS)

Christensen, A.B.; Tanner, J.E.; Knecht, D.A.

1980-09-01

This report demonstrates that a commercial-scale facility for encapsulating krypton-85 in zeolite-5A or glass at a 2000 MTHM per year nuclear fuel reprocessing plant can be designed to contain fragments and the 340 to 850 kCi krypton-85 inventory from an assumed catastrophic failure of the high pressure vessel. The vessel failure was assumed as a worst case and was not based on a detailed design evaluation or operating experience. The process design is based on existing commercial hot isostatic pressing technology operated at up to 40 times the scale required for krypton encapsulation. From the calculated process gas inventory in the pressure vessel and vessel design, the explosive energy of 8.4 kg TNT and vessel plug and fragment velocities were calculated. The facility Containment Cell housing the high pressure vessel was designed to contain the gases, fragments, and the shock wave energy calculated for vessel failure. The Access Cell located directly above the Containment Cell was designed to be a tertiary confinement of krypton-85, should the access hatch be breached

Guide to research facilities

Energy Technology Data Exchange (ETDEWEB)

1993-06-01

This Guide provides information on facilities at US Department of Energy (DOE) and other government laboratories that focus on research and development of energy efficiency and renewable energy technologies. These laboratories have opened these facilities to outside users within the scientific community to encourage cooperation between the laboratories and the private sector. The Guide features two types of facilities: designated user facilities and other research facilities. Designated user facilities are one-of-a-kind DOE facilities that are staffed by personnel with unparalleled expertise and that contain sophisticated equipment. Other research facilities are facilities at DOE and other government laboratories that provide sophisticated equipment, testing areas, or processes that may not be available at private facilities. Each facility listing includes the name and phone number of someone you can call for more information.

SSC string test facility for superconducting magnets: Testing capabilities and program for collider magnets

International Nuclear Information System (INIS)

Kraushaar, P.; Burgett, W.; Dombeck, T.; McInturff, A.; Robinson, W.; Saladin, V.

1993-05-01

The Accelerator Systems String Test (ASST) R ampersand D Testing Facility has been established at the SSC Laboratory to test Collider and High Energy Booster (HEB) superconducting magnet strings. The facility is operational and has had two testing periods utilizing a half cell of collider prototypical magnets with the associated spool pieces and support systems. This paper presents a description of the testing capabilities of the facility with respect to components and supporting subsystems (cryogenic, power, quench protection, controls and instrumentation), the planned testing program for the collider magnets

FFTF/IEM cell fuel pin weighing system

International Nuclear Information System (INIS)

Gibbons, P.W.

1987-01-01

The Interim Examination and Maintenance (IEM) cell in the Fast Flux Test Facility (FFTF) is used for remote disassembly of irradiated fuel and materials experiments. For those fuel experiments where the FFTF tag-gas detection system has indicated a fuel pin cladding breach, a weighing system is used in identifying that fuel pin with a reduced weight due to the escape of gaseous and volatile fission products. A fuel pin weighing machine, originally purchased for use in the Fuels and Materials Examination Facility (FMEF), was the basis for the IEM cell system. Design modifications to the original equipment were centered around adapting the machine to the differences between the two facilities and correcting deficiencies discovered during functional testing in the IEM cell mock-up

Experimental Fuels Facility Re-categorization Based on Facility Segmentation

Energy Technology Data Exchange (ETDEWEB)

Reiss, Troy P.; Andrus, Jason

2016-07-01

The Experimental Fuels Facility (EFF) (MFC-794) at the Materials and Fuels Complex (MFC) located on the Idaho National Laboratory (INL) Site was originally constructed to provide controlled-access, indoor storage for radiological contaminated equipment. Use of the facility was expanded to provide a controlled environment for repairing contaminated equipment and characterizing, repackaging, and treating waste. The EFF facility is also used for research and development services, including fuel fabrication. EFF was originally categorized as a LTHC-3 radiological facility based on facility operations and facility radiological inventories. Newly planned program activities identified the need to receive quantities of fissionable materials in excess of the single parameter subcritical limit in ANSI/ANS-8.1, “Nuclear Criticality Safety in Operations with Fissionable Materials Outside Reactors” (identified as “criticality list” quantities in DOE-STD-1027-92, “Hazard Categorization and Accident Analysis Techniques for Compliance with DOE Order 5480.23, Nuclear Safety Analysis Reports,” Attachment 1, Table A.1). Since the proposed inventory of fissionable materials inside EFF may be greater than the single parameter sub-critical limit of 700 g of U-235 equivalent, the initial re-categorization is Hazard Category (HC) 2 based upon a potential criticality hazard. This paper details the facility hazard categorization performed for the EFF. The categorization was necessary to determine (a) the need for further safety analysis in accordance with LWP-10802, “INL Facility Categorization,” and (b) compliance with 10 Code of Federal Regulations (CFR) 830, Subpart B, “Safety Basis Requirements.” Based on the segmentation argument presented in this paper, the final hazard categorization for the facility is LTHC-3. Department of Energy Idaho (DOE-ID) approval of the final hazard categorization determined by this hazard assessment document (HAD) was required per the

Infection prevention and control of the Ebola outbreak in Liberia, 2014-2015: key challenges and successes.

Science.gov (United States)

Cooper, Catherine; Fisher, Dale; Gupta, Neil; MaCauley, Rose; Pessoa-Silva, Carmem L

2016-01-05

Prior to the 2014-2015 Ebola outbreak, infection prevention and control (IPC) activities in Liberian healthcare facilities were basic. There was no national IPC guidance, nor dedicated staff at any level of government or healthcare facility (HCF) to ensure the implementation of best practices. Efforts to improve IPC early in the outbreak were ad hoc and messaging was inconsistent. In September 2014, at the height of the outbreak, the national IPC Task Force was established with a Ministry of Health (MoH) mandate to coordinate IPC response activities. A steering group of the Task Force, including representatives of the World Health Organization (WHO) and the United States Centers for Disease Control and Prevention (CDC), supported MoH leadership in implementing standardized messaging and IPC training for the health workforce. This structure, and the activities implemented under this structure, played a crucial role in the implementation of IPC practices and successful containment of the outbreak. Moving forward, a nationwide culture of IPC needs to be maintained through this governance structure in Liberia's health system to prevent and respond to future outbreaks.

Hanford Facility dangerous waste permit application, liquid effluent retention facility and 200 area effluent treatment facility

International Nuclear Information System (INIS)

Coenenberg, J.G.

1997-01-01

The Hanford Facility Dangerous Waste Permit Application is considered to 10 be a single application organized into a General Information Portion (document 11 number DOE/RL-91-28) and a Unit-Specific Portion. The scope of the 12 Unit-Specific Portion is limited to Part B permit application documentation 13 submitted for individual, 'operating' treatment, storage, and/or disposal 14 units, such as the Liquid Effluent Retention Facility and 200 Area Effluent 15 Treatment Facility (this document, DOE/RL-97-03). 16 17 Both the General Information and Unit-Specific portions of the Hanford 18 Facility Dangerous Waste Permit Application address the content of the Part B 19 permit application guidance prepared by the Washington State Department of 20 Ecology (Ecology 1987 and 1996) and the U.S. Environmental Protection Agency 21 (40 Code of Federal Regulations 270), with additional information needs 22 defined by the Hazardous and Solid Waste Amendments and revisions of 23 Washington Administrative Code 173-303. For ease of reference, the Washington 24 State Department of Ecology alpha-numeric section identifiers from the permit 25 application guidance documentation (Ecology 1996) follow, in brackets, the 26 chapter headings and subheadings. A checklist indicating where information is 27 contained in the Liquid Effluent Retention Facility and 200 Area Effluent 28 Treatment Facility permit application documentation, in relation to the 29 Washington State Department of Ecology guidance, is located in the Contents 30 Section. 31 32 Documentation contained in the General Information Portion is broader in 33 nature and could be used by multiple treatment, storage, and/or disposal units 34 (e.g., the glossary provided in the General Information Portion). Wherever 35 appropriate, the Liquid Effluent Retention Facility and 200 Area Effluent 36 Treatment Facility permit application documentation makes cross-reference to 37 the General Information Portion, rather than duplicating

Hanford Facility dangerous waste permit application, liquid effluent retention facility and 200 area effluent treatment facility

Energy Technology Data Exchange (ETDEWEB)

Coenenberg, J.G.

1997-08-15

The Hanford Facility Dangerous Waste Permit Application is considered to 10 be a single application organized into a General Information Portion (document 11 number DOE/RL-91-28) and a Unit-Specific Portion. The scope of the 12 Unit-Specific Portion is limited to Part B permit application documentation 13 submitted for individual, `operating` treatment, storage, and/or disposal 14 units, such as the Liquid Effluent Retention Facility and 200 Area Effluent 15 Treatment Facility (this document, DOE/RL-97-03). 16 17 Both the General Information and Unit-Specific portions of the Hanford 18 Facility Dangerous Waste Permit Application address the content of the Part B 19 permit application guidance prepared by the Washington State Department of 20 Ecology (Ecology 1987 and 1996) and the U.S. Environmental Protection Agency 21 (40 Code of Federal Regulations 270), with additional information needs 22 defined by the Hazardous and Solid Waste Amendments and revisions of 23 Washington Administrative Code 173-303. For ease of reference, the Washington 24 State Department of Ecology alpha-numeric section identifiers from the permit 25 application guidance documentation (Ecology 1996) follow, in brackets, the 26 chapter headings and subheadings. A checklist indicating where information is 27 contained in the Liquid Effluent Retention Facility and 200 Area Effluent 28 Treatment Facility permit application documentation, in relation to the 29 Washington State Department of Ecology guidance, is located in the Contents 30 Section. 31 32 Documentation contained in the General Information Portion is broader in 33 nature and could be used by multiple treatment, storage, and/or disposal units 34 (e.g., the glossary provided in the General Information Portion). Wherever 35 appropriate, the Liquid Effluent Retention Facility and 200 Area Effluent 36 Treatment Facility permit application documentation makes cross-reference to 37 the General Information Portion, rather than duplicating

Biomedical neutron research at the Californium User Facility for neutron science

International Nuclear Information System (INIS)

Martin, R.C.; Byrne, T.E.; Miller, L.F.

1997-01-01

The Californium User Facility for Neutron Science has been established at Oak Ridge National Laboratory (ORNL). The Californium User Facility (CUF) is a part of the larger Californium Facility, which fabricates and stores compact 252 Cf neutron sources for worldwide distribution. The CUF can provide a cost-effective option for research with 252 Cf sources. Three projects at the CUF that demonstrate the versatility of 252 Cf for biological and biomedical neutron-based research are described: future establishment of a 252 Cf-based neutron activation analysis system, ongoing work to produce miniature high-intensity, remotely afterloaded 252 Cf sources for tumor therapy, and a recent experiment that irradiated living human lung cancer cells impregnated with experimental boron compounds to test their effectiveness for boron neutron capture therapy

Facility effluent monitoring plan for 242-A evaporator facility

International Nuclear Information System (INIS)

Crummel, G.M.; Gustavson, R.D.

1995-02-01

A facility effluent monitoring plan is required by the U.S. Department of Energy in DOE Order 5400.1 for any operations that involve hazardous materials and radioactive substances that could affect employee or public safety or the environment. A facility effluent monitoring plan determination was performed during Calendar Year 1991 and the evaluation showed the need for a facility effluent monitoring plan. This document is prepared using the specific guidelines identified in A Guide for Preparing Hanford Site Facility Effluent Monitoring Plans, WHC-EP-0438-1. This facility effluent monitoring plan assesses effluent monitoring systems and evaluates whether they are adequate to ensure the public health and safety as specified in applicable federal, state, and local requirements. This facility effluent monitoring plan shall ensure long-range integrity of the effluent monitoring systems by requiring an update whenever a new process or operation introduces new hazardous materials or significant radioactive materials. This document must be reviewed annually even if there are no operational changes, and it must be updated, as a minimum, every three years

EPA Facility Registry Service (FRS): Facility Interests Dataset

Data.gov (United States)

U.S. Environmental Protection Agency — This web feature service consists of location and facility identification information from EPA's Facility Registry Service (FRS) for all sites that are available in...

Irradiation facilities on the TRIGA-SSR thermal column

Energy Technology Data Exchange (ETDEWEB)

Roth, C; Aioanei, L; Preda, M; Gugiu, D [Institute for Nuclear Research, Pitesti (Romania); Garlea, I; Kelerman, C; Garlea, C [SENDRA ' Nuclear Technologies' ltd. Bucharest (Romania)

2004-07-01

The development of thermal and intermediate energy neutron irradiation facilities at the steady state core of the Romanian TRIGA Reactor is described. The reference thermal neutron irradiation facility consists of a dry spherical cavity placed into the graphite thermal column of the SSR core and the intermediate energy neutron irradiation facility is a {sigma}{sigma} system located into the thermal flux cavity. The implementation of the irradiation facilities into the under-water thermal column represented an important challenge from the standpoint of instrumentation solutions. The neutron flux and spectrum measurements were performed using foil activation techniques and fission rate measurements by sealed fission chambers, followed by spectrum unfolding procedure. The absolute fission reaction measurements, using calibrated fission chambers, allow the neutron flux density unit transfer from international reference neutron fields. The MCNP-4C code package was used for neutron spectrum computations in the thermal flux cavity and in the {sigma}{sigma} system. The neutron characterization program demonstrates the accuracy of the spectrum characteristics and neutron flux densities reported to the local monitoring system count rates. Some discrepancies, as compared to other similar facilities, were identified and discussed. These are caused by thermal column particularities: the presence of a water layer between the graphite cells (thermal neutron absorption) and smaller geometrical dimensions (neutron escape phenomena). Based on these results the metrological certification process, according to Romanian metrological laws requirements, is now in progress. (nevyjel)

Probing stem cell differentiation using atomic force microscopy

International Nuclear Information System (INIS)

Liang, Xiaobin; Shi, Xuetao; Ostrovidov, Serge; Wu, Hongkai; Nakajima, Ken

2016-01-01

Graphical abstract: - Highlights: • Atomic force microscopy (AFM) was developed to probe stem cell differentiation. • The mechanical properties of stem cells and their ECMs can be used to clearly distinguish specific stem cell-differentiated lineages. • AFM is a facile and useful tool for monitoring stem cell differentiation in a non-invasive manner. - Abstract: A real-time method using atomic force microscopy (AFM) was developed to probe stem cell differentiation by measuring the mechanical properties of cells and the extracellular matrix (ECM). The mechanical properties of stem cells and their ECMs can be used to clearly distinguish specific stem cell-differentiated lineages. It is clear that AFM is a facile and useful tool for monitoring the differentiation of stem cells in a non-invasive manner.

Probing stem cell differentiation using atomic force microscopy

Energy Technology Data Exchange (ETDEWEB)

Liang, Xiaobin [Graduate School of Science and Engineering, Tokyo Institute of Technology, Ookayama 2-12-1, Meguro-ku, Tokyo 152-8550 (Japan); Shi, Xuetao, E-mail: mrshixuetao@gmail.com [School of Materials Science and Engineering, South China University of Technology, Guangzhou 510641 (China); Ostrovidov, Serge [WPI-Advanced Institute for Materials Research, Tohoku University, Sendai (Japan); Wu, Hongkai, E-mail: chhkwu@ust.hk [Department of Chemistry & Division of Biomedical Engineering, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong (China); Nakajima, Ken [Graduate School of Science and Engineering, Tokyo Institute of Technology, Ookayama 2-12-1, Meguro-ku, Tokyo 152-8550 (Japan)

2016-03-15

Graphical abstract: - Highlights: • Atomic force microscopy (AFM) was developed to probe stem cell differentiation. • The mechanical properties of stem cells and their ECMs can be used to clearly distinguish specific stem cell-differentiated lineages. • AFM is a facile and useful tool for monitoring stem cell differentiation in a non-invasive manner. - Abstract: A real-time method using atomic force microscopy (AFM) was developed to probe stem cell differentiation by measuring the mechanical properties of cells and the extracellular matrix (ECM). The mechanical properties of stem cells and their ECMs can be used to clearly distinguish specific stem cell-differentiated lineages. It is clear that AFM is a facile and useful tool for monitoring the differentiation of stem cells in a non-invasive manner.

Facile Preparation of TiO2 Nanobranch/Nanoparticle Hybrid Architecture with Enhanced Light Harvesting Properties for Dye-Sensitized Solar Cells

Directory of Open Access Journals (Sweden)

Ju Seong Kim

2015-01-01

Full Text Available We report TiO2 nanobranches/nanoparticles (NBN hybrid architectures that can be synthesized by a facile solution phase method. The hybrid architecture simultaneously improves light harvesting and charge collection performances for a dye-sensitized solar cell. First, TiO2 nanorods with a trunk length of 2 μm were grown on a fluorine-doped tin oxide (FTO/glass substrate, and then nanobranches and nanoparticles were deposited on the nanorods’ trunks through a solution method using an aqueous TiCl3 solution at 80°C. The relative amount of nanobranches and nanoparticles can be controlled by multiplying the number of TiCl3 treatments to maximize the amount of surface area. We found that the resultant TiO2 NBN hybrid architecture greatly improves the amount of dye adsorption (five times compared to bare nanorods due to the enhanced surface area, while maintaining a fast charge collection, leading to a three times higher current density and thus tripling the maximum power conversion efficiency for a dye-sensitized solar cell.

Facile and Scalable Fabrication of Highly Efficient Lead Iodide Perovskite Thin-Film Solar Cells in Air Using Gas Pump Method.

Science.gov (United States)

Ding, Bin; Gao, Lili; Liang, Lusheng; Chu, Qianqian; Song, Xiaoxuan; Li, Yan; Yang, Guanjun; Fan, Bin; Wang, Mingkui; Li, Chengxin; Li, Changjiu

2016-08-10

Control of the perovskite film formation process to produce high-quality organic-inorganic metal halide perovskite thin films with uniform morphology, high surface coverage, and minimum pinholes is of great importance to highly efficient solar cells. Herein, we report on large-area light-absorbing perovskite films fabrication with a new facile and scalable gas pump method. By decreasing the total pressure in the evaporation environment, the gas pump method can significantly enhance the solvent evaporation rate by 8 times faster and thereby produce an extremely dense, uniform, and full-coverage perovskite thin film. The resulting planar perovskite solar cells can achieve an impressive power conversion efficiency up to 19.00% with an average efficiency of 17.38 ± 0.70% for 32 devices with an area of 5 × 2 mm, 13.91% for devices with a large area up to 1.13 cm(2). The perovskite films can be easily fabricated in air conditions with a relative humidity of 45-55%, which definitely has a promising prospect in industrial application of large-area perovskite solar panels.

Safeguards approach for conditioning facility for spent fuel

International Nuclear Information System (INIS)

Younkin, J.M.; Barham, M.; Moran, B.W.

1999-01-01

A safeguards approach has been developed for conditioning facilities associated with the final disposal of spent fuel in geologic repositories. The proposed approach is based on a generic conditioning facility incorporating common features of conditioning facility designs currently proposed. The generic facility includes a hot cell for consolidation of spent fuel pins and repackaging of spent fuel items such as assemblies and cans of pins. The consolidation process introduces safeguards concerns which have not previously been addressed in traditional safeguards approaches. In developing the safeguards approach, diversion of spent fuel was assessed in terms of potential target items, operational activities performed on the items, containment of the items, and concealment activities performed on the items. The combination of these factors defines the potential diversion pathways. Diversion pathways were identified for spent fuel pellets, pins, assemblies, canisters, and casks. Diversion activities provide for opportunities of detection along the diversion paths. Potential detection methods were identified at several levels of diversion activities. Detection methods can be implemented through safeguards measures. Safeguards measures were proposed for each of the primary safeguards techniques of design information verification (DIV), containment and surveillance (C/S), and material accountancy. Potential safeguards approaches were developed by selection of appropriate combinations of safeguards measures. For all candidate safeguards approaches, DIV is a fundamental component. Variations in the approaches are mainly in the degree of C/S measures and in the types and numbers of material accountancy verification measures. The candidate safeguards approaches were evaluated toward the goal of determining a model safeguards approach. This model approach is based on the integrated application of selected safeguards measures to use International Atomic Energy Agency resources

Standard practice for cell sorting in a BSL-3 facility.

Science.gov (United States)

Perfetto, Stephen P; Ambrozak, David R; Nguyen, Richard; Roederer, Mario; Koup, Richard A; Holmes, Kevin L

2011-01-01

Over the past decade, there has been a rapid growth in the number of BSL-3 and BSL-4 laboratories in the USA and an increase in demand for infectious cell sorting in BSL-3 laboratories. In 2007, the International Society for Advancement of Cytometry (ISAC) Biosafety Committee published standards for the sorting of unfixed cells and is an important resource for biosafety procedures when performing infectious cell sorting. Following a careful risk assessment, if it is determined that a cell sorter must be located within a BSL-3 laboratory, there are a variety of factors to be considered prior to the establishment of the laboratory. This chapter outlines procedures for infectious cell sorting in a BSL-3 environment to facilitate the establishment and safe operation of a BSL-3 cell sorting laboratory. Subjects covered include containment verification, remote operation, disinfection, personal protective equipment (PPE), and instrument-specific modifications for enhanced aerosol evacuation.

Development of a standardized transfusion ratio as a metric for evaluating dialysis facility anemia management practices.

Science.gov (United States)

Liu, Jiannong; Li, Suying; Gilbertson, David T; Monda, Keri L; Bradbury, Brian D; Collins, Allan J

2014-10-01

Because transfusion avoidance has been the cornerstone of anemia treatment for patients with kidney disease, direct measurement of red blood cell transfusion use to assess dialysis facility anemia management performance is reasonable. We aimed to explore methods for estimating facility-level standardized transfusion ratios (STfRs) to assess provider anemia treatment practices. Retrospective cohort study. Point prevalent US hemodialysis patients on January 1, 2009, with Medicare as primary payer and dialysis duration of 90 days or longer were included (n = 223,901). All dialysis facilities with eligible patients were included (n = 5,345). Dialysis facility assignment. Receiving a red blood cell transfusion in the inpatient or outpatient setting. We evaluated 3 approaches for estimating STfR: ratio of observed to expected numbers of transfusions (STfR(obs)), a Bayesian approach (STfR(Bayes)), and a modified version of the Bayesian approach (STfR(modBayes)). The overall national transfusion rate in 2009 was 23.2 per 100 patient-years. Our model for predicting the expected number of transfusions performed well. For large facilities, all 3 STfRs worked well. However, for small facilities, while the STfR(modBayes) worked well, STfR(obs) values demonstrated instability and the STfR(Bayes) may produce more bias. Administration of transfusions to dialysis patients reflects medical practice both within and outside the dialysis unit. Some transfusions may be deemed unavoidable and transfusion practices are subject to considerable regional variation. Development of an STfR metric is feasible and reasonable for assessing anemia treatment at dialysis facilities. The STfR(obs) is simple to calculate and works well for larger dialysis facilities. The STfR(modBayes) is more analytically complex, but facilitates comparisons across all dialysis facilities, including small facilities. Copyright © 2014 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.

Use of an adaptable cell culture kit for performing lymphocyte and monocyte cell cultures in microgravity

Science.gov (United States)

Hatton, J. P.; Lewis, M. L.; Roquefeuil, S. B.; Chaput, D.; Cazenave, J. P.; Schmitt, D. A.

1998-01-01

The results of experiments performed in recent years on board facilities such as the Space Shuttle/Spacelab have demonstrated that many cell systems, ranging from simple bacteria to mammalian cells, are sensitive to the microgravity environment, suggesting gravity affects fundamental cellular processes. However, performing well-controlled experiments aboard spacecraft offers unique challenges to the cell biologist. Although systems such as the European 'Biorack' provide generic experiment facilities including an incubator, on-board 1-g reference centrifuge, and contained area for manipulations, the experimenter must still establish a system for performing cell culture experiments that is compatible with the constraints of spaceflight. Two different cell culture kits developed by the French Space Agency, CNES, were recently used to perform a series of experiments during four flights of the 'Biorack' facility aboard the Space Shuttle. The first unit, Generic Cell Activation Kit 1 (GCAK-1), contains six separate culture units per cassette, each consisting of a culture chamber, activator chamber, filtration system (permitting separation of cells from supernatant in-flight), injection port, and supernatant collection chamber. The second unit (GCAK-2) also contains six separate culture units, including a culture, activator, and fixation chambers. Both hardware units permit relatively complex cell culture manipulations without extensive use of spacecraft resources (crew time, volume, mass, power), or the need for excessive safety measures. Possible operations include stimulation of cultures with activators, separation of cells from supernatant, fixation/lysis, manipulation of radiolabelled reagents, and medium exchange. Investigations performed aboard the Space Shuttle in six different experiments used Jurkat, purified T-cells or U937 cells, the results of which are reported separately. We report here the behaviour of Jurkat and U937 cells in the GCAK hardware in ground

Nuclear Rocket Facility Decommissioning Project: Controlled Explosive Demolition of Neutron-Activated Shield Wall

International Nuclear Information System (INIS)

Michael R. Kruzic

2007-01-01

Located in Area 25 of the Nevada Test Site (NTS), the Test Cell A (TCA) Facility was used in the early to mid-1960s for the testing of nuclear rocket engines, as part of the Nuclear Rocket Development Program, to further space travel. Nuclear rocket testing resulted in the activation of materials around the reactors and the release of fission products and fuel particles in the immediate area. Identified as Corrective Action Unit 115, the TCA facility was decontaminated and decommissioned (D and D) from December 2004 to July 2005 using the Streamlined Approach for Environmental Restoration (SAFER) process, under the ''Federal Facility Agreement and Consent Order''. The SAFER process allows environmental remediation and facility closure activities (i.e., decommissioning) to occur simultaneously provided technical decisions are made by an experienced decision maker within the site conceptual site model, identified in the Data Quality Objective process. Facility closure involved a seven-step decommissioning strategy. Key lessons learned from the project included: (1) Targeted preliminary investigation activities provided a more solid technical approach, reduced surprises and scope creep, and made the working environment safer for the D and D worker. (2) Early identification of risks and uncertainties provided opportunities for risk management and mitigation planning to address challenges and unanticipated conditions. (3) Team reviews provided an excellent mechanism to consider all aspects of the task, integrated safety into activity performance, increase team unity and ''buy-in'' and promoted innovative and time saving ideas. (4) Development of CED protocols ensured safety and control. (5) The same proven D and D strategy is now being employed on the larger ''sister'' facility, Test Cell C

Biochemistry Facility

Data.gov (United States)

Federal Laboratory Consortium — The Biochemistry Facility provides expert services and consultation in biochemical enzyme assays and protein purification. The facility currently features 1) Liquid...

Facility effluent monitoring plan for the plutonium-uranium extraction facility

International Nuclear Information System (INIS)

Nickels, J.M.; Geiger, J.L.

1992-11-01

A facility effluent monitoring plan is required by the US Department of Energy in DOE Order 5400.1 for any operations that involve hazardous materials and radioactive substances that could impact employee or public safety or the environment. A facility effluent monitoring plan determination was performed during Calendar Year 1991 and the evaluation requires the need for a facility effluent monitoring plan. This document is prepared using the specific guidelines identified. in. A Guide for Preparing Hanford Site Facility Effluent Monitoring Plans, WHC-EP-0438. This facility effluent monitoring plan assesses effluent monitoring systems and evaluates whether they are adequate to ensure the public health and safety as specified in applicable federal, state, and local requirements

Jupiter Laser Facility

Data.gov (United States)

Federal Laboratory Consortium — The Jupiter Laser Facility is an institutional user facility in the Physical and Life Sciences Directorate at LLNL. The facility is designed to provide a high degree...

A facile inexpensive route for SnS thin film solar cells with SnS{sub 2} buffer

Energy Technology Data Exchange (ETDEWEB)

Gedi, Sreedevi [School of Chemical Engineering, Yeungnam University, 280Daehak-ro, Gyeongsan 712-749, Republic of Korea (Korea, Republic of); Solar Photovoltaic Laboratory, Department of Physics, Sri Venkateswasra University, Tirupati 517 502 (India); Minna Reddy, Vasudeva Reddy, E-mail: drmvasudr9@gmail.com [School of Chemical Engineering, Yeungnam University, 280Daehak-ro, Gyeongsan 712-749, Republic of Korea (Korea, Republic of); Solar Photovoltaic Laboratory, Department of Physics, Sri Venkateswasra University, Tirupati 517 502 (India); Pejjai, Babu [School of Chemical Engineering, Yeungnam University, 280Daehak-ro, Gyeongsan 712-749, Republic of Korea (Korea, Republic of); Solar Photovoltaic Laboratory, Department of Physics, Sri Venkateswasra University, Tirupati 517 502 (India); Jeon, Chan-Wook [School of Chemical Engineering, Yeungnam University, 280Daehak-ro, Gyeongsan 712-749, Republic of Korea (Korea, Republic of); Park, Chinho, E-mail: chpark@ynu.ac.kr [School of Chemical Engineering, Yeungnam University, 280Daehak-ro, Gyeongsan 712-749, Republic of Korea (Korea, Republic of); Ramakrishna Reddy, K.T., E-mail: ktrkreddy@gmail.com [Solar Photovoltaic Laboratory, Department of Physics, Sri Venkateswasra University, Tirupati 517 502 (India)

2016-05-30

Graphical abstract: PYS spectra of SnS/SnS{sub 2} interface and the related band diagram. - Highlights: • A low cost SnS solar cell is developed using chemical bath deposition. • We found E{sub I} & χ of SnS (5.3 eV & 4.0 eV) and SnS{sub 2} (6.9 eV & 4.1 eV) films from PYS. • Band offsets of 0.1 eV (E{sub c}) and 1.6 eV (E{sub v}) are estimated for SnS/SnS{sub 2} junction. • SnS based solar cell showed a conversion efficiency of 0.51%. - Abstract: Environment-friendly SnS based thin film solar cells with SnS{sub 2} as buffer layer were successfully fabricated from a facile inexpensive route, chemical bath deposition (CBD). Layer studies revealed that as-grown SnS and SnS{sub 2} films were polycrystalline; (1 1 1)/(0 0 1) peaks as the preferred orientation; 1.3 eV/2.8 eV as optical band gaps; and showed homogeneous microstructure with densely packed grains respectively. Ionization energy and electron affinity values were found by applying photoemission yield spectroscopy (PYS) to the CBD deposited SnS and SnS{sub 2} films for the first time. These values obtained as 5.3 eV and 4.0 eV for SnS films; 6.9 eV and 4.1 eV for SnS{sub 2} films. The band alignment of SnS/SnS{sub 2} junction showed TYPE-II heterostructure. The estimated conduction and valance band offsets were 0.1 eV and 1.6 eV respectively. The current density–voltage (J–V) measurements of the cell showed open circuit voltage (V{sub oc}) of 0.12 V, short circuit current density (J{sub sc}) of 10.87 mA cm{sup −2}, fill factor (FF) of 39% and conversion efficiency of 0.51%.

Liquid Effluent Retention Facility/Effluent Treatment Facility Hazards Assessment

International Nuclear Information System (INIS)

Simiele, G.A.

1994-01-01

This document establishes the technical basis in support of Emergency Planning activities for the Liquid Effluent Retention Facility and Effluent Treatment Facility the Hanford Site. The document represents an acceptable interpretation of the implementing guidance document for DOE ORDER 5500.3A. Through this document, the technical basis for the development of facility specific Emergency Action Levels and the Emergency Planning Zone is demonstrated

Biomedical neutron research at the Californium User Facility for Neutron Science

International Nuclear Information System (INIS)

Martin, R.C.; Byrne, T.E.; Miller, L.F.

1998-01-01

The Californium User Facility for Neutron Science has been established at Oak Ridge National Laboratory (ORNL). The Californium User Facility (CUF) is a part of the larger Californium Facility, which fabricates and stores compact 252 Cf neutron sources for worldwide distribution. The CUF can provide a cost-effective option for research with 252 Cf sources. Three projects at the CUF that demonstrate the versatility of 252 Cf for biological and biomedical neutron-based research are described: future establishment of a 252 Cf-based neutron activation analysis system, ongoing work to produce miniature high-intensity, remotely afterloaded 252 Cf sources for tumor therapy, and a recent experiment that irradiated living human lung cancer cells impregnated with experimental boron compounds to test their effectiveness for boron neutron capture therapy. (author)

Research Facilities | Wind | NREL

Science.gov (United States)

Research Facilities Research Facilities NREL's state-of-the-art wind research facilities at the Research Facilities Photo of five men in hard hards observing the end of a turbine blade while it's being tested. Structural Research Facilities A photo of two people silhouetted against a computer simulation of

Waste Facilities

Data.gov (United States)

Vermont Center for Geographic Information — This dataset was developed from the Vermont DEC's list of certified solid waste facilities. It includes facility name, contact information, and the materials...

Fabrication Facilities

Data.gov (United States)

Federal Laboratory Consortium — The Fabrication Facilities are a direct result of years of testing support. Through years of experience, the three fabrication facilities (Fort Hood, Fort Lewis, and...

TESLA Test Facility. Status

International Nuclear Information System (INIS)

Aune, B.

1996-01-01

The TESLA Test Facility (TTF), under construction at DESY by an international collaboration, is an R and D test bed for the superconducting option for future linear e+/e-colliders. It consists of an infrastructure to process and test the cavities and of a 500 MeV linac. The infrastructure has been installed and is fully operational. It includes a complex of clean rooms, an ultra-clean water plant, a chemical etching installation and an ultra-high vacuum furnace. The linac will consist of four cryo-modules, each containing eight 1 meter long nine-cell cavities operated at 1.3 GHz. The base accelerating field is 15 MV/m. A first injector will deliver a low charge per bunch beam, with the full average current (8 mA in pulses of 800 μs). A more powerful injector based on RF gun technology will ultimately deliver a beam with high charge and low emittance to allow measurements necessary to qualify the TESLA option and to demonstrate the possibility of operating a free electron laser based on the Self-Amplified-Spontaneous-Emission principle. Overview and status of the facility will be given. Plans for the future use of the linac are presented. (R.P.)

Radiological safety evaluation for a Waste Transfer Facility at Savannah River Site

International Nuclear Information System (INIS)

Ades, M.J.

1993-01-01

This paper provides a review of the radiological safety evaluation performed for a Waste Transfer Facility (WTF) located at the Savannah River Site (SRS). This facility transfers liquid radioactive waste between various waste processing facilities and waste storage facilities. The WTF includes functional components such as the diversion box and the pump pits, waste transfer lines, and the outside yard service piping and electrical services. The WSRC methodology is used to evaluate the consequences of postulated accidents that result in the release of radioactive material. Such accidents include transfer line breaks, underground liquid pathway release, fire in pump tank cells and HEPA filters, accidents due to natural phenomena, and externally induced events. Chemical hazards accidents are not considered. The analysis results indicate that the calculated mean onsite and offsite radiological consequences are bounded by the corresponding WSRC dose limits for each accident considered. Moreover, the results show that the maximum onsite and offsite doses calculated for the WTF are lower than the maximum doses determined for the whole radioactive waste facility where the WTF is located

Development of the Jyvaeskylae microbeam facility

Energy Technology Data Exchange (ETDEWEB)

Norarat, Rattanaporn, E-mail: rattanaporn.norarat@phys.jyu.fi [Department of Physics, University of Jyvaeskylae, P.O. Box 35 (YFL), FIN-40014 Jyvaeskylae (Finland); Sajavaara, Timo; Laitinen, Mikko; Heikkinen, Pauli; Ranttila, Kimmo; Ylikorkala, Kari; Haenninen, Vaeinoe; Rossi, Mikko; Jones, Pete [Department of Physics, University of Jyvaeskylae, P.O. Box 35 (YFL), FIN-40014 Jyvaeskylae (Finland); Marjomaeki, Varpu; Gilbert, Leona [Department of Environmental and Biological Sciences, University of Jyvaeskylae, P.O. Box 35 (YFL), FIN-40014 Jyvaeskylae (Finland); Whitlow, Harry J. [Department of Physics, University of Jyvaeskylae, P.O. Box 35 (YFL), FIN-40014 Jyvaeskylae (Finland)

2012-02-01

Research highlights: Black-Right-Pointing-Pointer A MeV ion microbeam for biomedical materials research is being developed. Black-Right-Pointing-Pointer High accuracy scanning using electrostatic post-focus deflection. Black-Right-Pointing-Pointer Imaging and direct lithographic image writing using time-stamping methods. Black-Right-Pointing-Pointer New scanning modes and fluorescence detectors permit low ion-fluence cell imaging. Black-Right-Pointing-Pointer Thermal compensated beam-line support design for high positional accuracy. - Abstract: A new microbeam facility is being constructed at the 1.7 MV Pelletron Accelerator in Jyvaeskylae. The facility is designed for easy upgrading and incorporates a number of innovative features. Initially, it is based on a Heidelberg doublet with a design capability of a 3 Multiplication-Sign 5 {mu}m beamspot at PIXE intensities and later upgraded to nanobeam performance. A thermal-expansion compensated rigid frame mounted on a mechanically isolated floor section is used to support the ion optical components. A compact-post focusing electrostatic deflector is used for high linearity beam scanning. This together with a novel time-stamped data collection (TDC) allows dynamic effects in IBIC, fluorescence bleaching to be studied as well as facilitating multi-resolution image support for low-fluence imaging of cells. The target chamber is fitted with a novel low-cost large working distance optical microscope, extremely compact large solid angle photon detectors as well as conventional secondary electron, PIXE and Scanning Transmission Ion Microscopy (STIM) detectors.

Diversity of gut microflora is required for the generation of B cell with regulatory properties in a skin graft model.

Science.gov (United States)

Alhabbab, R; Blair, P; Elgueta, R; Stolarczyk, E; Marks, E; Becker, P D; Ratnasothy, K; Smyth, L; Safinia, N; Sharif-Paghaleh, E; O'Connell, S; Noelle, R J; Lord, G M; Howard, J K; Spencer, J; Lechler, R I; Lombardi, G

2015-06-25

B cells have been reported to promote graft rejection through alloantibody production. However, there is growing evidence that B cells can contribute to the maintenance of tolerance. Here, we used a mouse model of MHC-class I mismatched skin transplantation to investigate the contribution of B cells to graft survival. We demonstrate that adoptive transfer of B cells prolongs skin graft survival but only when the B cells were isolated from mice housed in low sterility "conventional" (CV) facilities and not from mice housed in pathogen free facilities (SPF). However, prolongation of skin graft survival was lost when B cells were isolated from IL-10 deficient mice housed in CV facilities. The suppressive function of B cells isolated from mice housed in CV facilities correlated with an anti-inflammatory environment and with the presence of a different gut microflora compared to mice maintained in SPF facilities. Treatment of mice in the CV facility with antibiotics abrogated the regulatory capacity of B cells. Finally, we identified transitional B cells isolated from CV facilities as possessing the regulatory function. These findings demonstrate that B cells, and in particular transitional B cells, can promote prolongation of graft survival, a function dependent on licensing by gut microflora.

Diversity of gut microflora is required for the generation of B cell with regulatory properties in a skin graft model

Science.gov (United States)

Alhabbab, R.; Blair, P.; Elgueta, R.; Stolarczyk, E.; Marks, E.; Becker, P. D.; Ratnasothy, K.; Smyth, L.; Safinia, N.; Sharif-Paghaleh, E.; O’Connell, S.; Noelle, R. J.; Lord, G. M.; Howard, J. K.; Spencer, J.; Lechler, R. I.; Lombardi, G.

2015-01-01

B cells have been reported to promote graft rejection through alloantibody production. However, there is growing evidence that B cells can contribute to the maintenance of tolerance. Here, we used a mouse model of MHC-class I mismatched skin transplantation to investigate the contribution of B cells to graft survival. We demonstrate that adoptive transfer of B cells prolongs skin graft survival but only when the B cells were isolated from mice housed in low sterility “conventional” (CV) facilities and not from mice housed in pathogen free facilities (SPF). However, prolongation of skin graft survival was lost when B cells were isolated from IL-10 deficient mice housed in CV facilities. The suppressive function of B cells isolated from mice housed in CV facilities correlated with an anti-inflammatory environment and with the presence of a different gut microflora compared to mice maintained in SPF facilities. Treatment of mice in the CV facility with antibiotics abrogated the regulatory capacity of B cells. Finally, we identified transitional B cells isolated from CV facilities as possessing the regulatory function. These findings demonstrate that B cells, and in particular transitional B cells, can promote prolongation of graft survival, a function dependent on licensing by gut microflora. PMID:26109230

Lifecycle baseline summary for ADS 6504IS isotopes facilities Deactivation Project at Oak Ridge National Laboratory, Oak Ridge, Tennessee

International Nuclear Information System (INIS)

1995-08-01

The scope of this Activity Data Sheet (ADS) is to provide a detailed plan for the Isotopes Facilities Deactivation Project (IFDP) at the Oak Ridge National Laboratory (ORNL). This project places the former isotopes production facilities in a safe, stable, and environmentally sound condition suitable for an extended period of minimum surveillance and maintenance (S ampersand M) until the facilities are included in the Decontamination and Decommissioning (D ampersand D) Program. The facilities included within this deactivation project are Buildings 3026-C, 3026-D, 3028, 3029, 3038-AHF, 3038-E, 3038-M, 3047, 3517, 7025, and the Center Circle Facilities (Buildings 3030, 3031, 3032, 3033, 3033-A, 3034, and 3118). The scope of deactivation identified in this Baseline Report include surveillance and maintenance activities for each facility, engineering, contamination control and structural stabilization of each facility, radioluminescent (RL) light removal in Building 3026, re-roofing Buildings 3030, 3118, and 3031, Hot Cells Cleanup in Buildings 3047 and 3517, Yttrium (Y) Cell and Barricades Cleanup in Building 3038, Glove Boxes ampersand Hoods Removal in Buildings 3038 and 3047, and Inventory Transfer in Building 3517. For a detailed description of activities within this Work Breakdown Structure (WBS) element, see the Level 6 and Level 7 Element Definitions in Section 3.2 of this report

EPA Facility Registry Service (FRS): Facility Interests Dataset Download

Data.gov (United States)

U.S. Environmental Protection Agency — This downloadable data package consists of location and facility identification information from EPA's Facility Registry Service (FRS) for all sites that are...

Irradiation Facilities at CERN

CERN Document Server

Gkotse, Blerina; Carbonez, Pierre; Danzeca, Salvatore; Fabich, Adrian; Garcia, Alia, Ruben; Glaser, Maurice; Gorine, Georgi; Jaekel, Martin, Richard; Mateu,Suau, Isidre; Pezzullo, Giuseppe; Pozzi, Fabio; Ravotti, Federico; Silari, Marco; Tali, Maris

2017-01-01

CERN provides unique irradiation facilities for applications in many scientific fields. This paper summarizes the facilities currently operating for proton, gamma, mixed-field and electron irradiations, including their main usage, characteristics and information about their operation. The new CERN irradiation facilities database is also presented. This includes not only CERN facilities but also irradiation facilities available worldwide.

Preliminary safety evaluation of a commercial-scale krypton-85 encapsulation facility

International Nuclear Information System (INIS)

Christensen, A.B.; Tanner, J.E.; Knecht, D.A.

1980-01-01

This paper demonstrates that a commercial-scale facility for encapsulating krypton-85 in zeolite-5A or glass at a 2000 MTHM per year nuclear fuel reprocessing plant can be designed to contain fragments and the 340 to 850 kCi krypton-85 inventory from an assumed catastrophic failure of the high pressure vessel. The vessel failure was assumed as a worst case and was not based on a detailed design evaluation or operating experience. The process design is based on existing commercial hot isostatic pressing technology operated at up to 40 times the scale required for krypton encapsulation. From the calculated process gas inventory in the pressure vessel and vessel design, the maximum explosive energy of 8.4 kg TNT and resulting vessel plug and fragment velocities were calculated. The facility Containment Cell housing the high pressure vessel was designed to contain the gases, fragments, and the shock wave energy calculated for a hypothetical vessel failure. The Access Cell located directly above the Containment Cell was designed to be a tertiary confinement of krypton-85, should the access hatch be breached. 3 figures, 2 tables

Clean room installations in a radiopharmaceutical facility

International Nuclear Information System (INIS)

2000-01-01

The standards of radiopharmaceuticals on the facility, working environment and preparation control strategy are yet to be generated. In general, radiopharmaceuticals have short half-lives and emit gamma radiation. Due to its unique characteristics, its preparation has to be made in the fume hood and hot cell to avoid radiation exposure to workers. Considering radiation protection, the working environment has to be maintained under negative pressure so that dispersion of radiopharmaceuticals should be avoided. On the contrary, a positively pressurized working environment gives clean atmosphere and prevents contamination with harmful microorganisms during preparation. Hence, it is required to harmonize for mentioned contradictory conditions in preparation of radiopharmaceuticals for the safety of workers and its quality assurance as well. Therefore, it is reasonable that good manufacturing practice for radiopharmaceutical production facility should be constituted according to the standards for production of biological agents accompanied with a radiation shielding

Power Systems Development Facility. Quarterly report, July--September 1995

Energy Technology Data Exchange (ETDEWEB)

NONE

1995-11-01

The objective of this project is to evaluate hot gas particle control technologies using coal-derived gas streams. This will entail the design, construction, installation, and use of a flexible test facility which can operate under realistic gasification and combustion conditions. The major particulate control device issues to be addressed include the integration of the particulate control devices into coal utilization systems, on-line cleaning techniques, chemical and thermal degradation of components, fatigue or structural failures, blinding, collection efficiency as a fimction of particle size, and scale-up of particulate control systems to commercial size. The conceptual design of the facility was extended to include a within scope, phased expansion of the existing Hot Gas Cleanup Test Facility Cooperative Agreement to also address systems integration issues of hot particulate removal in advanced coal-based power generation systems. This expansion included the consideration of the following modules at the test facility in addition to the original Transport Reactor gas source and hot gas cleanup units: carbonizer/pressurized circulating fluidized bed gas source; hot gas cleanup units to mate to all gas streams; combustion gas turbine; and fuel cell and associated gas treatment. This expansion to the Hot Gas Cleanup Test Facility is herein referred to as the Power Systems Development Facility (PSDF). The major emphasis during this reporting period was continuing the detailed design of the facility towards completion and integrating the balance-of-plant processes and particulate control devices (PCDS) into the structural and process designs. Substantial progress in construction activities was achieved during the quarter. Delivery and construction of the process structural steel is nearing completion. Nearly all equipment are set in its place and the FW equipment and the PCDs are being set in the structure.

Shared and non-shared antigens from three different extracts of the metacestode of Echinococcus granulosus

Directory of Open Access Journals (Sweden)

David Carmena

2005-12-01

Full Text Available Hydatid cyst fluid (HCF, somatic antigens (S-Ag and excretory-secretory products (ES-Ag of Echinococcus granulosus protoscoleces are used as the main antigenic sources for immunodiagnosis of human and dog echinococcosis. In order to determine their non-shared as well as their shared antigenic components, these extracts were studied by ELISA-inhibition and immunoblot-inhibition. Assays were carried out using homologous rabbit polyclonal antisera, human sera from individuals with surgically confirmed hydatidosis, and sera from dogs naturally infected with E. granulosus. High levels of cross-reactivity were observed for all antigenic extracts, but especially for ES-Ag and S-Ag. Canine antibodies evidenced lesser avidity for their specific antigens than antibodies from human origin. The major antigenic components shared by HCF, S-Ag, and ES-Ag have apparent molecular masses of 4-6, 20-24, 52, 80, and 100-104 kDa, including doublets of 41/45, 54/57, and 65/68 kDa. Non-shared polypeptides of each antigenic extract of E. granulosus were identified, having apparent masses of 108 and 78 kDa for HCF, of 124, 94, 83, and 75 kDa for S-Ag, and of 89, 66, 42, 39, 37, and 35 kDa for ES-Ag.

EPA Facility Registry Service (FRS): Facility Interests Dataset - Intranet

Data.gov (United States)

U.S. Environmental Protection Agency — This web feature service consists of location and facility identification information from EPA's Facility Registry Service (FRS) for all sites that are available in...

Hanford Facility Dangerous Waste Permit Application, 200 Area Effluent Treatment Facility

International Nuclear Information System (INIS)

1993-08-01