WorldWideScience

Sample records for cell commercialization roadmap

  1. Fuel Cell Technical Team Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    None

    2013-06-01

    The Fuel Cell Technical Team promotes the development of a fuel cell power system for an automotive powertrain that meets the U.S. DRIVE Partnership (United States Driving Research and Innovation for Vehicle efficiency and Energy sustainability) goals.

  2. Roadmap for the Future of Commercial Energy Codes

    Energy Technology Data Exchange (ETDEWEB)

    Rosenberg, Michael I.; Hart, Philip R.; Zhang, Jian; Athalye, Rahul A.

    2015-01-26

    Building energy codes have significantly increased building efficiency over the last 38 years, since the first national energy code was published in 1975. The most commonly used path in energy codes, the prescriptive path, appears to be reaching a point of diminishing returns. The current focus on prescriptive codes has limitations including significant variation in actual energy performance depending on which prescriptive options are chosen, a lack of flexibility for designers and developers, the inability to handle optimization that is specific to building type and use, the inability to account for project-specific energy costs, and the lack of follow-through or accountability after a certificate of occupancy is granted. It is likely that an approach that considers the building as an integrated system will be necessary to achieve the next real gains in building efficiency. This report provides a high-level review of different formats for commercial building energy codes, including prescriptive, prescriptive packages, capacity constrained, outcome based, and predictive performance approaches. This report also explores a next generation commercial energy code approach that places a greater emphasis on performance-based criteria. For commercial building energy codes to continue to progress as they have over the last 40 years, the next generation of building codes will need to provide a path that is led by energy performance, ensuring a measurable trajectory toward net zero energy buildings. This report outlines a vision to serve as a roadmap for future commercial code development. That vision is based on code development being led by a specific approach to predictive energy performance combined with building-specific prescriptive packages that are designed both to be cost-effective and to achieve a desired level of performance. Compliance with this new approach can be achieved by either meeting the performance target, as demonstrated by whole building energy

  3. Roadmap for the Future of Commercial Energy Codes

    Energy Technology Data Exchange (ETDEWEB)

    Rosenberg, Michael I. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Hart, Philip R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Zhang, Jian [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Athalye, Rahul A. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2015-01-01

    Building energy codes have significantly increased building efficiency over the last 38 years, since the first national energy code was published in 1975. The most commonly used path in energy codes, the prescriptive path, appears to be reaching a point of diminishing returns. The current focus on prescriptive codes has limitations including significant variation in actual energy performance depending on which prescriptive options are chosen, a lack of flexibility for designers and developers, the inability to handle optimization that is specific to building type and use, the inability to account for project-specific energy costs, and the lack of follow-through or accountability after a certificate of occupancy is granted. It is likely that an approach that considers the building as an integrated system will be necessary to achieve the next real gains in building efficiency. This report provides a high-level review of different formats for commercial building energy codes, including prescriptive, prescriptive packages, capacity constrained, outcome based, and predictive performance approaches. This report also explores a next generation commercial energy code approach that places a greater emphasis on performance-based criteria.

  4. planSOEC. R and D and commercialization roadmap for SOEC electrolysis. R and D of SOEC stacks with improved durability. Project report

    Energy Technology Data Exchange (ETDEWEB)

    Richter, A.; Friis Pedersen, C.; Nielsen, Jens Ulrik [Topsoe Fuel Cells A/S, Kgs. Lyngby (Denmark); Mogensen, M.; Hoejgaard Jensen, S.; Ming Chen [Technical Univ. of Denmark. Fuel Cells and Solid State Chemistry Div., DTU Risoe Campus, Roskilde (Denmark); Sloth, M. [H2 Logic A/S, Herning (Denmark)

    2011-05-15

    The project has been divided into two parts: PART 1: Formulation of a R and D and commercialization roadmap for SOEC electrolysis. PART 2: Conducting R and D of SOEC stacks with improved durability. The purpose of Part 1 has been to develop a R and D and commercialisation roadmap for hydrogen and CO production plants based on the solid oxide electrolysis cell (SOEC) technology. SOEC technology is still on an early R and D stage but years of extensive R and D within SOFC technology provides a strong platform for an accelerated commercialisation. However, in order to guide the future SOEC R and D activities towards reaching commercial market requirements a detailed roadmap is necessary. An overall strategy for R and D of various electrolysis technologies in Denmark already exists{sup 2}, formulated in the Hydrogen Production working group in the Danish Hydrogen and Fuel Cell Partnership. The SOEC roadmap developed as part of the planSOEC project supplements the overall strategy, by conducting an updated analysis of state-of-the-art. Also planSOEC provides a detailed analysis of requirements for different market applications for SOEC, which enables formulation of precise and detailed R and D targets. The objectives of Part 2 in this project were multiple: 1) To investigate durability of solid oxide cells (SOCs) and stack components under industrially relevant (''harsh'') electrolysis operating conditions; 2) to investigate performance of standard TOFC (Topsoe Fuel Cell A/S) SOC stacks (based on state-of-the-art solid oxide cells) under mild electrolysis operating conditions ({<=}0.75 A/cm{sup 2}); 3) to further develop SOEC stack computer models available at Riso DTU and TOFC. Accordingly four lines of work were carried out in the here reported project: 1) Investigation of corrosion resistance of interconnect alloys. 2) Cell and stack element testing. 3) SOEC stack testing. 4) SOEC stack modeling. (LN)

  5. Non-Hardware ("Soft") Cost-Reduction Roadmap for Residential and Small Commercial Solar Photovoltaics, 2013-2020

    Energy Technology Data Exchange (ETDEWEB)

    Ardani, K.; Seif, D.; Margolis, R.; Morris, J.; Davidson, C.; Truitt, S.; Torbert, R.

    2013-08-01

    The objective of this analysis is to roadmap the cost reductions and innovations necessary to achieve the U.S. Department of Energy (DOE) SunShot Initiative's total soft-cost targets by 2020. The roadmap focuses on advances in four soft-cost areas: (1) customer acquisition; (2) permitting, inspection, and interconnection (PII); (3) installation labor; and (4) financing. Financing cost reductions are in terms of the weighted average cost of capital (WACC) for financing PV system installations, with real-percent targets of 3.0% (residential) and 3.4% (commercial).

  6. A Cost Roadmap for Silicon Heterojunction Solar Cells

    NARCIS (Netherlands)

    Louwen, A.; van Sark, W.G.J.H.M.; Schropp, Ruud; Faaij, A.

    2016-01-01

    Research and development of silicon heterojunction (SHJ) solar cells has seen a marked increase since the recent expiry of core patents describing SHJ technology. SHJ solar cells are expected to offer various cost benefits compared to conventional crystalline silicon solar cells. This paper analyses

  7. Navigating the transcriptional roadmap regulating plant secondary cell wall deposition

    Directory of Open Access Journals (Sweden)

    Steven Grant Hussey

    2013-08-01

    Full Text Available The current status of lignocellulosic biomass as an invaluable resource in industry, agriculture and health has spurred increased interest in understanding the transcriptional regulation of secondary cell wall (SCW biosynthesis. The last decade of research has revealed an extensive network of NAC, MYB and other families of transcription factors regulating Arabidopsis SCW biosynthesis, and numerous studies have explored SCW-related transcription factors in other dicots and monocots. Whilst the general structure of the Arabidopsis network has been a topic of several reviews, they have not comprehensively represented the detailed protein-DNA and protein-protein interactions described in the literature, and an understanding of network dynamics and functionality has not yet been achieved for SCW formation. Furthermore the methodologies employed in studies of SCW transcriptional regulation have not received much attention, especially in the case of non-model organisms. In this review, we have reconstructed the most exhaustive literature-based network representations to date of SCW transcriptional regulation in Arabidopsis. We include a manipulable Cytoscape representation of the Arabidopsis SCW transcriptional network to aid in future studies, along with a list of supporting literature for each documented interaction. Amongst other topics, we discuss the various components of the network, its evolutionary conservation in plants, putative modules and dynamic mechanisms that may influence network function, and the approaches that have been employed in network inference. Future research should aim to better understand network function and its response to dynamic perturbations, whilst the development and application of genome-wide approaches such as ChIP-seq and systems genetics are in progress for the study of SCW transcriptional regulation in non-model organisms.

  8. Scientific Assessment in support of the Materials Roadmap enabling Low Carbon Energy Technologies: Hydrogen and Fuel Cells

    DEFF Research Database (Denmark)

    Cerri, I.; Lefebvre-Joud, F.; Holtappels, Peter

    A group of experts from European research organisations and industry have assessed the state of the art and future needs for materials' R&D for hydrogen and fuel cell technologies. The work was performed as input to the European Commission's roadmapping exercise on materials for the European...

  9. Vehicle Battery Safety Roadmap Guidance

    Energy Technology Data Exchange (ETDEWEB)

    Doughty, D. H.

    2012-10-01

    The safety of electrified vehicles with high capacity energy storage devices creates challenges that must be met to assure commercial acceptance of EVs and HEVs. High performance vehicular traction energy storage systems must be intrinsically tolerant of abusive conditions: overcharge, short circuit, crush, fire exposure, overdischarge, and mechanical shock and vibration. Fail-safe responses to these conditions must be designed into the system, at the materials and the system level, through selection of materials and safety devices that will further reduce the probability of single cell failure and preclude propagation of failure to adjacent cells. One of the most important objectives of DOE's Office of Vehicle Technologies is to support the development of lithium ion batteries that are safe and abuse tolerant in electric drive vehicles. This Roadmap analyzes battery safety and failure modes of state-of-the-art cells and batteries and makes recommendations on future investments that would further DOE's mission.

  10. BMT Roadmap: A User-Centered Design Health Information Technology Tool to Promote Patient-Centered Care in Pediatric Hematopoietic Cell Transplantation.

    Science.gov (United States)

    Runaas, Lyndsey; Hanauer, David; Maher, Molly; Bischoff, Evan; Fauer, Alex; Hoang, Tiffany; Munaco, Anna; Sankaran, Roshun; Gupta, Rahael; Seyedsalehi, Sajjad; Cohn, Amy; An, Larry; Tewari, Muneesh; Choi, Sung Won

    2017-05-01

    Health information technology (HIT) has great potential for increasing patient engagement. Pediatric hematopoietic cell transplantation (HCT) is a setting ripe for using HIT but in which little research exists. "BMT Roadmap" is a web-based application that integrates patient-specific information and includes several domains: laboratory results, medications, clinical trial details, photos of the healthcare team, trajectory of transplant process, and discharge checklist. BMT Roadmap was provided to 10 caregivers of patients undergoing first-time HCT. Research assistants performed weekly qualitative interviews throughout the patient's hospitalization and at discharge and day 100 to assess the impact of BMT Roadmap. Rigorous thematic analysis revealed 5 recurrent themes: emotional impact of the HCT process itself; critical importance of communication among patients, caregivers, and healthcare providers; ways in which BMT Roadmap was helpful during inpatient setting; suggestions for improving BMT Roadmap; and other strategies for organization and management of complex healthcare needs that could be incorporated into BMT Roadmap. Caregivers found the tool useful and easy to use, leading them to want even greater access to information. BMT Roadmap was feasible, with no disruption to inpatient care. Although this initial study is limited by the small sample size and single-institution experience, these initial findings are encouraging and support further investigation.

  11. National Algal Biofuels Technology Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    Ferrell, John [Dept. of Energy (DOE), Washington DC (United States); Sarisky-Reed, Valerie [Dept. of Energy (DOE), Washington DC (United States)

    2010-05-01

    The framework for National Algal Biofuels Technology Roadmap was constructed at the Algal Biofuels Technology Roadmap Workshop, held December 9-10, 2008, at the University of Maryland-College Park. The Workshop was organized by the Biomass Program to discuss and identify the critical challenges currently hindering the development of a domestic, commercial-scale algal biofuels industry. This Roadmap presents information from a scientific, economic, and policy perspectives that can support and guide RD&D investment in algal biofuels. While addressing the potential economic and environmental benefits of using algal biomass for the production of liquid transportation fuels, the Roadmap describes the current status of algae RD&D. In doing so, it lays the groundwork for identifying challenges that likely need to be overcome for algal biomass to be used in the production of economically viable biofuels.

  12. Exploration and Mining Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2002-09-01

    This Exploration and Mining Technology Roadmap represents the third roadmap for the Mining Industry of the Future. It is based upon the results of the Exploration and Mining Roadmap Workshop held May 10 ñ 11, 2001.

  13. Pressure Garment Subsystem Roadmap

    Science.gov (United States)

    Ross, Amy J.

    2010-01-01

    The Constellation program pressure garment subsystem (PGS) team has created a technical roadmap that communicates major technical questions and how and when the questions are being answered in support of major project milestones. The roadmap is a living document that guides the team priorities. The roadmap also communicates technical reactions to changes in project priorities and funding. This paper presents the roadmap and discusses specific roadmap elements in detail as representative examples to provide insight into the meaning and use of the roadmap.

  14. Codes & standards research, development & demonstration Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2008-07-22

    This Roadmap is a guide to the Research, Development & Demonstration activities that will provide data required for SDOs to develop performance-based codes and standards for a commercial hydrogen fueled transportation sector in the U.S.

  15. Research & Development Roadmap for Next-Generation Appliances

    Energy Technology Data Exchange (ETDEWEB)

    Goetzler, William [Navigant Consulting, Inc., Burlington, MA (United States); Sutherland, Timothy [Navigant Consulting, Inc., Burlington, MA (United States); Foley, Kevin [Navigant Consulting, Inc., Burlington, MA (United States)

    2012-03-01

    Appliances present an attractive opportunity for near-term energy savings in existing building, because they are less expensive and replaced more regularly than heating, ventilation, and air-conditioning (HVAC) systems or building envelope components. This roadmap targets high-priority research and development (R&D), demonstration and commercialization activities that could significantly reduce residential appliance energy consumption. The main objective of the roadmap is to seek activities that accelerate the commercialization of high-efficiency appliance technologies while maintaining the competitiveness of American industry. The roadmap identified and evaluated potential technical innovations, defined research needs, created preliminary research and development roadmaps, and obtained stakeholder feedback on the proposed initiatives.

  16. Stationary power fuel cell commercialization status worldwide

    Energy Technology Data Exchange (ETDEWEB)

    Williams, M.C. [Dept. of Energy, Morgantown, WV (United States)

    1996-12-31

    Fuel cell technologies for stationary power are set to play a role in power generation applications worldwide. The worldwide fuel cell vision is to provide powerplants for the emerging distributed generation and on-site markets. Progress towards commercialization has occurred in all fuel cell development areas. Around 100 ONSI phosphoric acid fuel cell (PAFC) units have been sold, with significant foreign sales in Europe and Japan. Fuji has apparently overcome its PAFC decay problems. Industry-driven molten carbonate fuel cell (MCFC) programs in Japan and the U.S. are conducting megawatt (MW)-class demonstrations, which are bringing the MCFC to the verge of commercialization. Westinghouse Electric, the acknowledged world leader in tubular solid oxide fuel cell (SOFC) technology, continues to set performance records and has completed construction of a 4-MW/year manufacturing facility in the U.S. Fuel cells have also taken a major step forward with the conceptual development of ultra-high efficiency fuel cell/gas turbine plants. Many SOFC developers in Japan, Europe, and North America continue to make significant advances.

  17. Aluminum Industry Technology Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2003-02-01

    This roadmap describes the industry's R&D strategy, priorities, milestones, and performance targets for achieving its long-term goals. It accounts for changes in the industry and the global marketplace since the first roadmap was published in 1997. An updated roadmap was published November 2001. (PDF 1.1 MB).

  18. Codes and standards research, development and demonstration roadmap

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2008-07-22

    C&S RD&D Roadmap - 2008: This Roadmap is a guide to the Research, Development & Demonstration activities that will provide data required for Standards Development Organizations (SDOs) to develop performance-based codes and standards for a commercial hydrogen fueled transportation sector in the U.S.

  19. Roadmap on optical security

    Science.gov (United States)

    Javidi, Bahram; Carnicer, Artur; Yamaguchi, Masahiro; Nomura, Takanori; Pérez-Cabré, Elisabet; Millán, María S.; Nishchal, Naveen K.; Torroba, Roberto; Fredy Barrera, John; He, Wenqi; Peng, Xiang; Stern, Adrian; Rivenson, Yair; Alfalou, A.; Brosseau, C.; Guo, Changliang; Sheridan, John T.; Situ, Guohai; Naruse, Makoto; Matsumoto, Tsutomu; Juvells, Ignasi; Tajahuerce, Enrique; Lancis, Jesús; Chen, Wen; Chen, Xudong; Pinkse, Pepijn W. H.; Mosk, Allard P.; Markman, Adam

    2016-08-01

    Information security and authentication are important challenges facing society. Recent attacks by hackers on the databases of large commercial and financial companies have demonstrated that more research and development of advanced approaches are necessary to deny unauthorized access to critical data. Free space optical technology has been investigated by many researchers in information security, encryption, and authentication. The main motivation for using optics and photonics for information security is that optical waveforms possess many complex degrees of freedom such as amplitude, phase, polarization, large bandwidth, nonlinear transformations, quantum properties of photons, and multiplexing that can be combined in many ways to make information encryption more secure and more difficult to attack. This roadmap article presents an overview of the potential, recent advances, and challenges of optical security and encryption using free space optics. The roadmap on optical security is comprised of six categories that together include 16 short sections written by authors who have made relevant contributions in this field. The first category of this roadmap describes novel encryption approaches, including secure optical sensing which summarizes double random phase encryption applications and flaws [Yamaguchi], the digital holographic encryption in free space optical technique which describes encryption using multidimensional digital holography [Nomura], simultaneous encryption of multiple signals [Pérez-Cabré], asymmetric methods based on information truncation [Nishchal], and dynamic encryption of video sequences [Torroba]. Asymmetric and one-way cryptosystems are analyzed by Peng. The second category is on compression for encryption. In their respective contributions, Alfalou and Stern propose similar goals involving compressed data and compressive sensing encryption. The very important area of cryptanalysis is the topic of the third category with two sections

  20. Accurate Promoter and Enhancer Identification in 127 ENCODE and Roadmap Epigenomics Cell Types and Tissues by GenoSTAN

    Science.gov (United States)

    Zacher, Benedikt; Michel, Margaux; Schwalb, Björn; Cramer, Patrick; Tresch, Achim

    2017-01-01

    Accurate maps of promoters and enhancers are required for understanding transcriptional regulation. Promoters and enhancers are usually mapped by integration of chromatin assays charting histone modifications, DNA accessibility, and transcription factor binding. However, current algorithms are limited by unrealistic data distribution assumptions. Here we propose GenoSTAN (Genomic STate ANnotation), a hidden Markov model overcoming these limitations. We map promoters and enhancers for 127 cell types and tissues from the ENCODE and Roadmap Epigenomics projects, today’s largest compendium of chromatin assays. Extensive benchmarks demonstrate that GenoSTAN generally identifies promoters and enhancers with significantly higher accuracy than previous methods. Moreover, GenoSTAN-derived promoters and enhancers showed significantly higher enrichment of complex trait-associated genetic variants than current annotations. Altogether, GenoSTAN provides an easy-to-use tool to define promoters and enhancers in any system, and our annotation of human transcriptional cis-regulatory elements constitutes a rich resource for future research in biology and medicine. PMID:28056037

  1. Enterprise Architecture (EA) Roadmap

    Data.gov (United States)

    Office of Personnel Management — The Enterprise Roadmap reflects the information technology (IT) investment priorities established in agency PortfolioStat reviews, as well as IT program decisions...

  2. Characterization of a Commercial Silicon Beta Cell

    Energy Technology Data Exchange (ETDEWEB)

    Foxe, Michael P. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Hayes, James C. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Mayer, Michael F. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); McIntyre, Justin I. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Sivels, Ciara B. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Suarez, Rey [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2016-03-31

    Silicon detectors are of interest for the verification of the Comprehensive Nuclear-Test-Ban Treaty (CTBT) due to their enhanced energy resolution compared to plastic scintillators beta cells. Previous work developing a figure-of-merit (FOM) for comparison of beta cells suggests that the minimum detectable activity (MDA) could be reduced by a factor of two to three with the use of silicon detectors. Silicon beta cells have been developed by CEA (France) and Lares Ltd. (Russia), with the PIPSBox developed by CEA being commercially available from Canberra for approximately $35k, but there is still uncertainty about the reproducibility of the capabilities in the field. PNNL is developing a high-resolution beta-gamma detector system in the shallow underground laboratory, which will utilize and characterize the operation of the PIPSBox detector. Throughout this report, we examine the capabilities of the PIPSBox as developed by CEA. The lessons learned through the testing and use of the PIPSBox will allow PNNL to strategically develop a silicon detector optimized to better suit the communities needs in the future.

  3. Mineral Processing Technology Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2000-09-01

    This document represents the roadmap for Processing Technology Research in the US Mining Industry. It was developed based on the results of a Processing Technology Roadmap Workshop sponsored by the National Mining Association in conjunction with the US Department of Energy, Office of Energy Efficiency and Renewable Energy, Office of Industrial Technologies. The Workshop was held January 24 - 25, 2000.

  4. SSIP Phase I Roadmap

    Science.gov (United States)

    Vinh, Megan; Lucas, Anne; Taylor, Cornelia; Kelley, Grace; Kasprzak, Christina

    2014-01-01

    This roadmap provides a description of the activities involved in the development of the State Systemic Improvement Plan (SSIP) (SPP/APR Indicators C11 and B17) due to the Office of Special Education Programs (OSEP) on April 1, 2015. The roadmap is intended to support states with completing Phase I of the SSIP process. This document provides…

  5. The Epigenetic Reprogramming Roadmap in Generation of iPSCs from Somatic Cells

    DEFF Research Database (Denmark)

    Brix, Jacob; Zhou, Yan; Luo, Yonglun

    2015-01-01

    Reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) is a comprehensive epigenetic process involving genome-wide modifications of histones and DNA methylation. This process is often incomplete, which subsequently affects iPSC reprograming, pluripotency, and differentiation cap...

  6. The Epigenetic Reprogramming Roadmap in Generation of iPSCs from Somatic Cells.

    Science.gov (United States)

    Brix, Jacob; Zhou, Yan; Luo, Yonglun

    2015-12-20

    Reprogramming of somatic cells to induced pluripotent stem cells (iPSCs) is a comprehensive epigenetic process involving genome-wide modifications of histones and DNA methylation. This process is often incomplete, which subsequently affects iPSC reprogramming, pluripotency, and differentiation capacity. Here, we review the epigenetic changes with a focus on histone modification (methylation and acetylation) and DNA modification (methylation) during iPSC induction. We look at changes in specific epigenetic signatures, aberrations and epigenetic memory during reprogramming and small molecules influencing the epigenetic reprogramming of somatic cells. Finally, we discuss how to improve iPSC generation and pluripotency through epigenetic manipulations.

  7. Fundamentals of technology roadmapping

    Energy Technology Data Exchange (ETDEWEB)

    Garcia, M.L.; Bray, O.H.

    1997-04-01

    Technology planning is important for many reasons. Globally, companies are facing many competitive problems. Technology roadmapping, a form of technology planning can help deal with this increasingly competitive environment. While it has been used by some companies and industries, the focus has always been on the technology roadmap as a product, not on the process. This report focuses on formalizing the process so that it can be more broadly and easily used. As a DOE national security laboratory with R&D as a major product, Sandia must do effective technology planning to identify and develop the technologies required to meet its national security mission. Once identified, technology enhancements or new technologies may be developed internally or collaboratively with external partners. For either approach, technology roadmapping, as described in this report, is an effective tool for technology planning and coordination, which fits within a broader set of planning activities. This report, the second in a series on technology roadmapping, develops and documents this technology roadmapping process, which can be used by Sandia, other national labs, universities, and industry. The main benefit of technology roadmapping is that it provides information to make better technology investment decisions by identifying critical technologies and technology gaps and identifying ways to leverage R&D investments. It can also be used as a marketing tool. Technology roadmapping is critical when the technology investment decision is not straight forward. This occurs when it is not clear which alternative to pursue, how quickly the technology is needed, or when there is a need to coordinate the development of multiple technologies. The technology roadmapping process consists of three phases - preliminary activity, development of the technology roadmap, and follow-up activity.

  8. Flight Avionics Hardware Roadmap

    Science.gov (United States)

    Some, Raphael; Goforth, Monte; Chen, Yuan; Powell, Wes; Paulick, Paul; Vitalpur, Sharada; Buscher, Deborah; Wade, Ray; West, John; Redifer, Matt; Partridge, Harry; Sherman, Aaron; McCabe, Mary

    2014-01-01

    The Avionics Technology Roadmap takes an 80% approach to technology investment in spacecraft avionics. It delineates a suite of technologies covering foundational, component, and subsystem-levels, which directly support 80% of future NASA space mission needs. The roadmap eschews high cost, limited utility technologies in favor of lower cost, and broadly applicable technologies with high return on investment. The roadmap is also phased to support future NASA mission needs and desires, with a view towards creating an optimized investment portfolio that matures specific, high impact technologies on a schedule that matches optimum insertion points of these technologies into NASA missions. The roadmap looks out over 15+ years and covers some 114 technologies, 58 of which are targeted for TRL6 within 5 years, with 23 additional technologies to be at TRL6 by 2020. Of that number, only a few are recommended for near term investment: 1. Rad Hard High Performance Computing 2. Extreme temperature capable electronics and packaging 3. RFID/SAW-based spacecraft sensors and instruments 4. Lightweight, low power 2D displays suitable for crewed missions 5. Radiation tolerant Graphics Processing Unit to drive crew displays 6. Distributed/reconfigurable, extreme temperature and radiation tolerant, spacecraft sensor controller and sensor modules 7. Spacecraft to spacecraft, long link data communication protocols 8. High performance and extreme temperature capable C&DH subsystem In addition, the roadmap team recommends several other activities that it believes are necessary to advance avionics technology across NASA: center dot Engage the OCT roadmap teams to coordinate avionics technology advances and infusion into these roadmaps and their mission set center dot Charter a team to develop a set of use cases for future avionics capabilities in order to decouple this roadmap from specific missions center dot Partner with the Software Steering Committee to coordinate computing hardware

  9. Energy Roadmap 2050

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-02-15

    On 15 December 2011, the European Commission adopted the Communication 'Energy Roadmap 2050'. The EU is committed to reducing greenhouse gas emissions to 80-95% below 1990 levels by 2050 in the context of necessary reductions by developed countries as a group. In the Energy Roadmap 2050 the Commission explores the challenges posed by delivering the EU's decarbonisation objective while at the same time ensuring security of energy supply and competitiveness. The Energy Roadmap 2050 is the basis for developing a long-term European framework together with all stakeholders.

  10. Roadmap on optical energy conversion

    Energy Technology Data Exchange (ETDEWEB)

    Boriskina, Svetlana V.; Green, Martin A.; Catchpole, Kylie; Yablonovitch, Eli; Beard, Matthew C.; Okada, Yoshitaka; Lany, Stephan; Gershon, Talia; Zakutayev, Andriy; Tahersima, Mohammad H.; Sorger, Volker J.; Naughton, Michael J.; Kempa, Krzysztof; Dagenais, Mario; Yao, Yuan; Xu, Lu; Sheng, Xing; Bronstein, Noah D.; Rogers, John A.; Alivisatos, A. Paul; Nuzzo, Ralph G.; Gordon, Jeffrey M.; Wu, Di M.; Wisser, Michael D.; Salleo, Alberto; Dionne, Jennifer; Bermel, Peter; Greffet, Jean-Jacques; Celanovic, Ivan; Soljacic, Marin; Manor, Assaf; Rotschild, Carmel; Raman, Aaswath; Zhu, Linxiao; Fan, Shanhui; Chen, Gang

    2016-06-24

    For decades, progress in the field of optical (including solar) energy conversion was dominated by advances in the conventional concentrating optics and materials design. In recent years, however, conceptual and technological breakthroughs in the fields of nanophotonics and plasmonics combined with a better understanding of the thermodynamics of the photon energy-conversion processes reshaped the landscape of energy-conversion schemes and devices. Nanostructured devices and materials that make use of size quantization effects to manipulate photon density of states offer a way to overcome the conventional light absorption limits. Novel optical spectrum splitting and photon-recycling schemes reduce the entropy production in the optical energy-conversion platforms and boost their efficiencies. Optical design concepts are rapidly expanding into the infrared energy band, offering new approaches to harvest waste heat, to reduce the thermal emission losses, and to achieve noncontact radiative cooling of solar cells as well as of optical and electronic circuitries. Light-matter interaction enabled by nanophotonics and plasmonics underlie the performance of the third- and fourth-generation energy-conversion devices, including up- and down-conversion of photon energy, near-field radiative energy transfer, and hot electron generation and harvesting. Finally, the increased market penetration of alternative solar energy-conversion technologies amplifies the role of cost-driven and environmental considerations. This roadmap on optical energy conversion provides a snapshot of the state of the art in optical energy conversion, remaining challenges, and most promising approaches to address these challenges. Leading experts authored 19 focused short sections of the roadmap where they share their vision on a specific aspect of this burgeoning research field. The roadmap opens up with a tutorial section, which introduces major concepts and terminology. It is our hope that the roadmap

  11. Roadmap on optical energy conversion

    Science.gov (United States)

    Boriskina, Svetlana V.; Green, Martin A.; Catchpole, Kylie; Yablonovitch, Eli; Beard, Matthew C.; Okada, Yoshitaka; Lany, Stephan; Gershon, Talia; Zakutayev, Andriy; Tahersima, Mohammad H.; Sorger, Volker J.; Naughton, Michael J.; Kempa, Krzysztof; Dagenais, Mario; Yao, Yuan; Xu, Lu; Sheng, Xing; Bronstein, Noah D.; Rogers, John A.; Alivisatos, A. Paul; Nuzzo, Ralph G.; Gordon, Jeffrey M.; Wu, Di M.; Wisser, Michael D.; Salleo, Alberto; Dionne, Jennifer; Bermel, Peter; Greffet, Jean-Jacques; Celanovic, Ivan; Soljacic, Marin; Manor, Assaf; Rotschild, Carmel; Raman, Aaswath; Zhu, Linxiao; Fan, Shanhui; Chen, Gang

    2016-07-01

    For decades, progress in the field of optical (including solar) energy conversion was dominated by advances in the conventional concentrating optics and materials design. In recent years, however, conceptual and technological breakthroughs in the fields of nanophotonics and plasmonics combined with a better understanding of the thermodynamics of the photon energy-conversion processes reshaped the landscape of energy-conversion schemes and devices. Nanostructured devices and materials that make use of size quantization effects to manipulate photon density of states offer a way to overcome the conventional light absorption limits. Novel optical spectrum splitting and photon-recycling schemes reduce the entropy production in the optical energy-conversion platforms and boost their efficiencies. Optical design concepts are rapidly expanding into the infrared energy band, offering new approaches to harvest waste heat, to reduce the thermal emission losses, and to achieve noncontact radiative cooling of solar cells as well as of optical and electronic circuitries. Light-matter interaction enabled by nanophotonics and plasmonics underlie the performance of the third- and fourth-generation energy-conversion devices, including up- and down-conversion of photon energy, near-field radiative energy transfer, and hot electron generation and harvesting. Finally, the increased market penetration of alternative solar energy-conversion technologies amplifies the role of cost-driven and environmental considerations. This roadmap on optical energy conversion provides a snapshot of the state of the art in optical energy conversion, remaining challenges, and most promising approaches to address these challenges. Leading experts authored 19 focused short sections of the roadmap where they share their vision on a specific aspect of this burgeoning research field. The roadmap opens up with a tutorial section, which introduces major concepts and terminology. It is our hope that the roadmap

  12. Metalcasting Industry Technology Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    none,

    1998-01-01

    The Roadmap sets out the strategy for pursuing near-, mid-, and long-term goals set out by industry and for carrying out the cooperative agreement between the U.S. Department of Energy and industry. The Roadmap outlines key goals for products and markets, materials technology, manufacturing technology, environmental technology, human resources, and industry health programs. The Roadmap sets out the strategy for pursuing near-, mid-, and long-term goals set out by industry and for carrying out the cooperative agreement between the U.S. Department of Energy and industry. The Roadmap sets out the strategy for pursuing near-, mid-, and long-term goals set out by industry and for carrying out the cooperative agreement between the U.S. Department of Energy and industry.

  13. ULS Systems Research Roadmap

    Science.gov (United States)

    2008-03-01

    capability Framework for incorporating additional ULS systems research Motivate Research • The roadmap shows how an individual research initiative...6.2.2 Metaheuristics in Software Engineering 6.2.3 Digital Evolution 6.3.1 Design of All Levels 6.3.2 Design Spaces and Design Rules 6.3.3 Harnessing...achieving a future ULS systems capability Framework for incorporating additional ULS systems research Motivate Research • The roadmap shows how an

  14. The 2012 Plasma Roadmap

    Science.gov (United States)

    Samukawa, Seiji; Hori, Masaru; Rauf, Shahid; Tachibana, Kunihide; Bruggeman, Peter; Kroesen, Gerrit; Whitehead, J. Christopher; Murphy, Anthony B.; Gutsol, Alexander F.; Starikovskaia, Svetlana; Kortshagen, Uwe; Boeuf, Jean-Pierre; Sommerer, Timothy J.; Kushner, Mark J.; Czarnetzki, Uwe; Mason, Nigel

    2012-06-01

    Low-temperature plasma physics and technology are diverse and interdisciplinary fields. The plasma parameters can span many orders of magnitude and applications are found in quite different areas of daily life and industrial production. As a consequence, the trends in research, science and technology are difficult to follow and it is not easy to identify the major challenges of the field and their many sub-fields. Even for experts the road to the future is sometimes lost in the mist. Journal of Physics D: Applied Physics is addressing this need for clarity and thus providing guidance to the field by this special Review article, The 2012 Plasma Roadmap. Although roadmaps are common in the microelectronic industry and other fields of research and development, constructing a roadmap for the field of low-temperature plasmas is perhaps a unique undertaking. Realizing the difficulty of this task for any individual, the plasma section of the Journal of Physics D Board decided to meet the challenge of developing a roadmap through an unusual and novel concept. The roadmap was divided into 16 formalized short subsections each addressing a particular key topic. For each topic a renowned expert in the sub-field was invited to express his/her individual visions on the status, current and future challenges, and to identify advances in science and technology required to meet these challenges. Together these contributions form a detailed snapshot of the current state of the art which clearly shows the lifelines of the field and the challenges ahead. Novel technologies, fresh ideas and concepts, and new applications discussed by our authors demonstrate that the road to the future is wide and far reaching. We hope that this special plasma science and technology roadmap will provide guidance for colleagues, funding agencies and government institutions. If successful in doing so, the roadmap will be periodically updated to continue to help in guiding the field.

  15. Technology Roadmaps: Solar photovoltaic energy

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-07-01

    Solar PV power is a commercially available and reliable technology with a significant potential for long-term growth in nearly all world regions. This roadmap estimates that by 2050, PV will provide around 11% of global electricity production and avoid 2.3 gigatonnes (Gt) of CO2 emissions per year. Achieving this roadmap's vision will require an effective, long-term and balanced policy effort in the next decade to allow for optimal technology progress, cost reduction and ramp-up of industrial manufacturing for mass deployment. Governments will need to provide long-term targets and supporting policies to build confidence for investments in manufacturing capacity and deployment of PV systems. PV will achieve grid parity -- i.e. competitiveness with electricity grid retail prices -- by 2020 in many regions. As grid parity is achieved, the policy framework should evolve towards fostering self-sustained markets, with the progressive phase-out of economic incentives, but maintaining grid access guarantees and sustained R&D support.

  16. 2010 Hydrogen and Fuel Cell Global Commercialization & Development Update

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2010-11-01

    This report offers examples of real-world applications and technical progress of hydrogen and fuel cell technologies, including policies adopted by countries to increase technology development and commercialization.

  17. Compromises of Bali Roadmap

    Institute of Scientific and Technical Information of China (English)

    Wang Jingmin; Wei Dong

    2008-01-01

    The Bali Roadmap, as the breakthrough on intergovernmental negotiation of climate change mitigation, having brought United States on track, is still a result of compromises. The major compromises of the Bali Roadmap are centered around three issues of quantifying emission reduction targets, developing countries' obligations as well as quantifying developed countries' financial assistance in developing countries' capacity building on climate change. It is found that the rationalities behind these compromises are the national interests. Due to the fact, achieving cohesion among all nations in climate change actions is very difficult. Therefore, the Bali Roadmap may lead to a tough way with distant hope. However, technology innovation and well-designed economic instruments would be helpful and supportive for further international negotiation and cooperation.

  18. Commercialization of fuel cells: myth or reality?

    CERN Document Server

    Wang, Junye

    2014-01-01

    Despite huge investment and efforts in the last decades, fuel cells are still known as a fledgling industry after 170 years of the first fuel cell. It becomes clear that these investment and efforts did not address the critical questions. Why upscaling of fuel cells failed often when many researchers stated their successes in small scale? Why the fuel cells with simpler structure still lag far from the internal combustion (IC) engines and gas turbines? Could the current investment of the hydrogen infrastructure reduce substantially the fuel cell cost and make a breakthrough to the key issues of durability, reliability and robustness? In this paper, we study these fundamental questions and point out a must-way possible to reduce cost of fuel cells and to substantially improve durability and reliability.

  19. OHVT technology roadmap [2000

    Energy Technology Data Exchange (ETDEWEB)

    Bradley, R.A.

    2000-02-01

    The OHVT Technology Roadmap for 2000 presents the multiyear program plan of the U.S. DOE's Office of Heavy Vehicle Technologies (OHVT). It is an update of the 1997 plan, reflecting changes in regulations and ongoing discussions with DOE's heavy vehicle customers. The technical plan covers three classes of trucks: (1) class 7-8 (large, on-highway trucks); (2) class 3-6 (medium duty trucks); (3) class 1-2 (pickups, vans, and sport utility vehicles) as well as enabling and supporting technologies. The Roadmap documents program goals, schedules, and milestones.

  20. National hydrogen energy roadmap

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2002-11-01

    This report was unveiled by Energy Secretary Spencer Abraham in November 2002 and provides a blueprint for the coordinated, long-term, public and private efforts required for hydrogen energy development. Based on the results of the government-industry National Hydrogen Energy Roadmap Workshop, held in Washington, DC on April 2-3, 2002, it displays the development of a roadmap for America's clean energy future and outlines the key barriers and needs to achieve the hydrogen vision goals defined in

  1. Technology Roadmaps: Cement

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-07-01

    To support its roadmap work focusing on key technologies for emissions reductions, the International Energy Agency (IEA) also investigated one particular industry: cement. Cement production includes technologies that are both specific to this industry and those that are shared with other industries (e.g., grinding, fuel preparation, combustion, crushing, transport). An industry specific roadmap provides an effective mechanism to bring together several technology options. It outlines the potential for technological advancement for emissions reductions in one industry, as well as potential cross-industry collaboration.

  2. Roadmap on structured light

    Science.gov (United States)

    Rubinsztein-Dunlop, Halina; Forbes, Andrew; Berry, M. V.; Dennis, M. R.; Andrews, David L.; Mansuripur, Masud; Denz, Cornelia; Alpmann, Christina; Banzer, Peter; Bauer, Thomas; Karimi, Ebrahim; Marrucci, Lorenzo; Padgett, Miles; Ritsch-Marte, Monika; Litchinitser, Natalia M.; Bigelow, Nicholas P.; Rosales-Guzmán, C.; Belmonte, A.; Torres, J. P.; Neely, Tyler W.; Baker, Mark; Gordon, Reuven; Stilgoe, Alexander B.; Romero, Jacquiline; White, Andrew G.; Fickler, Robert; Willner, Alan E.; Xie, Guodong; McMorran, Benjamin; Weiner, Andrew M.

    2017-01-01

    Structured light refers to the generation and application of custom light fields. As the tools and technology to create and detect structured light have evolved, steadily the applications have begun to emerge. This roadmap touches on the key fields within structured light from the perspective of experts in those areas, providing insight into the current state and the challenges their respective fields face. Collectively the roadmap outlines the venerable nature of structured light research and the exciting prospects for the future that are yet to be realized.

  3. Current status of the TSensor systems roadmap

    NARCIS (Netherlands)

    Walsh, Steven; Bryzek, Janusz; Pisano, Albert P.

    2014-01-01

    We apply our work from the contemporary pharmaceutical industry to generate a third generation-style technology roadmap for TSensor Systems. First we identify drivers and consortia. We then identify relevant technology components, namely multiple root technologies, multiple unit cells, multiple crit

  4. Technology roadmap for lithium ion batteries 2030; Technologie-Roadmap Lithium-Ionen-Batterien 2030

    Energy Technology Data Exchange (ETDEWEB)

    Thielmann, Axel; Isenmann, Ralf; Wietschel, Martin [Fraunhofer-Institut fuer Systemtechnik und Innovationsforschung (ISI), Karlsruhe (Germany)

    2010-07-01

    The technology roadmap for lithium ion batteries 2030 presents a graphical representation of the cell components, cell types and cell characteristics of lithium ion batteries and their connection with the surrounding technology field from today through 2030. This is a farsighted orientation on the way into the future and an implementation of the ''Roadmap: Batterieforschung Deutschland'' of the BMBF (Federal Ministry of Education and Science). The developments in lithium ion batteries are identified through 2030 form today's expert view in battery development and neighbouring areas. (orig.)

  5. Roadmap on neurophotonics

    Science.gov (United States)

    Cho, Yong Ku; Zheng, Guoan; Augustine, George J.; Hochbaum, Daniel; Cohen, Adam; Knöpfel, Thomas; Pisanello, Ferruccio; Pavone, Francesco S.; Vellekoop, Ivo M.; Booth, Martin J.; Hu, Song; Zhu, Jiang; Chen, Zhongping; Hoshi, Yoko

    2016-09-01

    Mechanistic understanding of how the brain gives rise to complex behavioral and cognitive functions is one of science’s grand challenges. The technical challenges that we face as we attempt to gain a systems-level understanding of the brain are manifold. The brain’s structural complexity requires us to push the limit of imaging resolution and depth, while being able to cover large areas, resulting in enormous data acquisition and processing needs. Furthermore, it is necessary to detect functional activities and ‘map’ them onto the structural features. The functional activity occurs at multiple levels, using electrical and chemical signals. Certain electrical signals are only decipherable with sub-millisecond timescale resolution, while other modes of signals occur in minutes to hours. For these reasons, there is a wide consensus that new tools are necessary to undertake this daunting task. Optical techniques, due to their versatile and scalable nature, have great potentials to answer these challenges. Optical microscopy can now image beyond the diffraction limit, record multiple types of brain activity, and trace structural features across large areas of tissue. Genetically encoded molecular tools opened doors to controlling and detecting neural activity using light in specific cell types within the intact brain. Novel sample preparation methods that reduce light scattering have been developed, allowing whole brain imaging in rodent models. Adaptive optical methods have the potential to resolve images from deep brain regions. In this roadmap article, we showcase a few major advances in this area, survey the current challenges, and identify potential future needs that may be used as a guideline for the next steps to be taken.

  6. Materials Technical Team Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2013-08-01

    Roadmap identifying the efforts of the Materials Technical Team (MTT) to focus primarily on reducing the mass of structural systems such as the body and chassis in light-duty vehicles (including passenger cars and light trucks) which enables improved vehicle efficiency regardless of the vehicle size or propulsion system employed.

  7. Roadmap of Infinite Results

    DEFF Research Database (Denmark)

    Srba, Jiří

    2002-01-01

    This paper provides a comprehensive summary of equivalence checking results for infinite-state systems. References to the relevant papers will be updated continuously according to the development in the area. The most recent version of this document is available from the web-page http://www.brics.dk/~srba/roadmap....

  8. Heat Roadmap Europe

    DEFF Research Database (Denmark)

    Connolly, David; Lund, Henrik; Mathiesen, Brian Vad;

    2014-01-01

    Six different strategies have recently been proposed for the European Union (EU) energy system in the European Commission's report, Energy Roadmap 2050. The objective for these strategies is to identify how the EU can reach its target of an 80% reduction in annual greenhouse gas emissions in 2050...

  9. National solar technology roadmap: Nano-architecture PV

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Yong [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2007-06-01

    This roadmap addresses nano-architecture solar cells that use nanowires, nanotubes, and nanocrystals, including single-component, core-shell, embedded nanowires or nanocrystals either as absorbers or transporters.

  10. Roadmap 2030: The U.S. Concrete Industry Technology Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2002-12-01

    Roadmap 2030: The U.S. Concrete Industry Technology Roadmap tracks the eight goals published in the American Concrete Institute Strategic Development Council's Vision 2030: A Vision for the U.S. Concrete Industry. Roadmap 2030 highlights existing state-of-the-art technologies and emerging scientific advances that promise high potential for innovation, and predicts future technological needs. It defines enabling research opportunities and proposes areas where governmental-industrial-academic partnerships can accelerate the pace of development. Roadmap 2030 is a living document designed to continually address technical, institutional, and market changes.

  11. Determination of thermal properties of commercial Ni-MH cells

    Science.gov (United States)

    Darcy, Eric C.

    1994-01-01

    The test objectives were to evaluate the electrical and thermal performance of commercial Ni-MH cells, evaluate the effectiveness of commercial charge control circuits, assess the abuse tolerance of these cells, and correlate performance and abuse tolerances to cell design via disassembly. Design objectives were to determine which cell designs are most suitable for scale-up and to guide the design of future shuttle and space station based battery chargers. Results, displayed in viewgraph format, include: reflex charging with ICS circuit resulted in premature charge termination; Ni-MH cells appear very tolerant to overcharge at low rates; Enstore's charger is more electrically and thermally efficient at high rates; and Ni-MH cycles much more efficiently than Ni-Cd with the delta-V/delta-t termination.

  12. Optical analysis of CH3NH3Sn x Pb1-x I3 absorbers: a roadmap for perovskite-on-perovskite tandem solar cells.

    Science.gov (United States)

    Anaya, Miguel; Correa-Baena, Juan P; Lozano, Gabriel; Saliba, Michael; Anguita, Pablo; Roose, Bart; Abate, Antonio; Steiner, Ullrich; Grätzel, Michael; Calvo, Mauricio E; Hagfeldt, Anders; Míguez, Hernán

    2016-08-07

    Organic-inorganic perovskite structures in which lead is substituted by tin are exceptional candidates for broadband light absorption. Herein we present a thorough analysis of the optical properties of CH3NH3Sn x Pb1-x I3 films, providing the field with definitive insights about the possibilities of these materials for perovskite solar cells of superior efficiency. We report a user's guide based on the first set of optical constants obtained for a series of tin/lead perovskite films, which was only possible to measure due to the preparation of optical quality thin layers. According to the Shockley-Queisser theory, CH3NH3Sn x Pb1-x I3 compounds promise a substantial enhancement of both short circuit photocurrent and power conversion efficiency in single junction solar cells. Moreover, we propose a novel tandem architecture design in which both top and bottom cells are made of perovskite absorbers. Our calculations indicate that such perovskite-on-perovskite tandem devices could reach efficiencies over 35%. Our analysis serves to establish the first roadmap for this type of cells based on actual optical characterization data. We foresee that this study will encourage the research on novel near-infrared perovskite materials for photovoltaic applications, which may have implications in the rapidly emerging field of tandem devices.

  13. OHVT technology roadmap

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-10-01

    The Office of Heavy Vehicle Technologies (OHVT) Technology Roadmap presents the OHVT multiyear program plan. It was developed in response to recommendations by DOE`s heavy vehicle industry customers, including truck and bus manufacturers, diesel engine manufacturers, fuel producers, suppliers to these industries, and the trucking industry. The technical plan is presented for three classes of trucks: (1) class 7-8 (large, on-highway trucks); (2) class 3-6 (medium duty trucks); and (3) class 1-2 (pickups, vans, and sport utility vehicles). The Roadmap documents program goals, technical targets, and technical approaches. Issues addressed include engine efficiency, fuel efficiency, power requirements, emissions, and fuel flexibility. 8 figs., 9 tabs.

  14. Technology Roadmaps: Smart Grids

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    The development of Technology Roadmaps: Smart Grids -- which the IEA defines as an electricity network that uses digital and other advanced technologies to monitor and manage the transport of electricity from all generation sources to meet the varying electricity demands of end users -- is essential if the global community is to achieve shared goals for energy security, economic development and climate change mitigation. Unfortunately, existing misunderstandings of exactly what smart grids are and the physical and institutional complexity of electricity systems make it difficult to implement smart grids on the scale that is needed. This roadmap sets out specific steps needed over the coming years to achieve milestones that will allow smart grids to deliver a clean energy future.

  15. National Hydrogen Roadmap Workshop Proceedings

    Energy Technology Data Exchange (ETDEWEB)

    None

    2002-04-01

    This document summarizes the presentations and suggestions put forth by officials, industry experts and policymakers in their efforts to come together to develop a roadmap for America''s clean energy future and outline the key barriers and needs to achieve the hydrogen vision. The National Hydrogen Roadmap Workshop was held April 2-3, 2002. These proceedings were compiled into a formal report, The National Hydrogen Energy Roadmap, which is also available online.

  16. The NASA Astrobiology Roadmap

    Science.gov (United States)

    Des Marais, David J.; Allamandola, Louis J.; Benner, Steven A.; Boss, Alan P.; Deamer, David; Falkowski, Paul G.; Farmer, Jack D.; Hedges, S. Blair; Jakosky, Bruce M.; Knoll, Andrew H.; Liskowsky, David R.; Meadows, Victoria S.; Meyer, Michael A.; Pilcher, Carl B.; Nealson, Kenneth H.; Spormann, Alfred M.; Trent, Jonathan D.; Turner, William W.; Woolf, Neville J.; Yorke, Harold W.

    2003-01-01

    The NASA Astrobiology Roadmap provides guidance for research and technology development across the NASA enterprises that encompass the space, Earth, and biological sciences. The ongoing development of astrobiology roadmaps embodies the contributions of diverse scientists and technologists from government, universities, and private institutions. The Roadmap addresses three basic questions: How does life begin and evolve, does life exist elsewhere in the universe, and what is the future of life on Earth and beyond? Seven Science Goals outline the following key domains of investigation: understanding the nature and distribution of habitable environments in the universe, exploring for habitable environments and life in our own solar system, understanding the emergence of life, determining how early life on Earth interacted and evolved with its changing environment, understanding the evolutionary mechanisms and environmental limits of life, determining the principles that will shape life in the future, and recognizing signatures of life on other worlds and on early Earth. For each of these goals, Science Objectives outline more specific high-priority efforts for the next 3-5 years. These 18 objectives are being integrated with NASA strategic planning.

  17. The NASA Astrobiology Roadmap.

    Science.gov (United States)

    Des Marais, David J; Nuth, Joseph A; Allamandola, Louis J; Boss, Alan P; Farmer, Jack D; Hoehler, Tori M; Jakosky, Bruce M; Meadows, Victoria S; Pohorille, Andrew; Runnegar, Bruce; Spormann, Alfred M

    2008-08-01

    The NASA Astrobiology Roadmap provides guidance for research and technology development across the NASA enterprises that encompass the space, Earth, and biological sciences. The ongoing development of astrobiology roadmaps embodies the contributions of diverse scientists and technologists from government, universities, and private institutions. The Roadmap addresses three basic questions: how does life begin and evolve, does life exist elsewhere in the universe, and what is the future of life on Earth and beyond? Seven Science Goals outline the following key domains of investigation: understanding the nature and distribution of habitable environments in the universe, exploring for habitable environments and life in our own Solar System, understanding the emergence of life, determining how early life on Earth interacted and evolved with its changing environment, understanding the evolutionary mechanisms and environmental limits of life, determining the principles that will shape life in the future, and recognizing signatures of life on other worlds and on early Earth. For each of these goals, Science Objectives outline more specific high priority efforts for the next three to five years. These eighteen objectives are being integrated with NASA strategic planning.

  18. Effects of Reference Performance Testing During Aging Using Commercial Cells

    Energy Technology Data Exchange (ETDEWEB)

    Jon P. Christophersen; Chinh D. Ho; David Howell

    2005-07-01

    The Advanced Technology Development Program, under the oversight of the U.S. Department of Energy’s FreedomCAR and Vehicle Technologies Program, is investigating lithium-ion batteries for hybrid-electric vehicle applications. Cells are aged under various test conditions, including temperatures and states-of-charge. Life testing is interrupted at regular intervals to conduct reference performance tests (RPTs), which are used to measure changes in the electrical performance of the cells and then to determine cell degradation as a function of test time. Although designed to be unobtrusive, data from the Advanced Technology Development Gen 2 cells indicated that RPTs actually contributed to cell degradation and failure. A study was performed at the Idaho National Laboratory using commercially available lithium-ion cells to determine the impact of RPTs on life. A series of partial RPTs were performed at regular intervals during life testing and compared to a control group that was life tested without RPT interruption. It was determined that certain components of the RPT were detrimental, while others appeared to improve cell performance. Consequently, a new "mini" RPT was designed as an unobtrusive alternative. Initial testing with commercial cells indicates that the impact of the mini RPT is significantly less than the Gen 2 cell RPT.

  19. Education Roadmap for Mining Professionals

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2002-12-01

    This document represents the roadmap for education in the U.S. mining industry. It was developed based on the results of an Education Roadmap Workshop sponsored by the National Mining Association in conjunction with the U.S. Department of Energy, Office of Energy Efficiency and Renewable Energy, Office of Industrial Technologies. The Workshop was held February 23, 2002 in Phoenix, Arizona.

  20. Safety Limitations Associated with Commercial 18650 Lithium-ion Cells

    Science.gov (United States)

    Jeevarajan, Judith A.

    2010-01-01

    In the past decade, NASA-JSC battery group has carried out several tests on the safety of li-ion cells, modules and battery packs. The hazards associated with using commercial li-ion cells in high voltage and high capacity batteries have been determined to be different from those associated with the use of the same cells in low voltage, low capacity packs (less than 15 V and 60 Wh). Tests carried out included overcharge, overdischarge, external and internal short circuits with destructive physical analysis included in most cases. Chemical analysis, X-rays and in some cases CT scans were used for post-test analysis.

  1. Performance Characterization of High Energy Commercial Lithium-ion Cells

    Science.gov (United States)

    Schneidegger, Brianne T.

    2010-01-01

    The NASA Glenn Research Center Electrochemistry Branch performed characterization of commercial lithium-ion cells to determine the cells' performance against Exploration Technology Development Program (ETDP) Key Performance Parameters (KPP). The goals of the ETDP Energy Storage Project require significant improvements in the specific energy of lithium-ion technology over the state-of-the-art. This work supports the high energy cell development for the Constellation customer Lunar Surface Systems (LSS). In support of these goals, testing was initiated in September 2009 with high energy cylindrical cells obtained from Panasonic and E-One Moli. Both manufacturers indicated the capability of their cells to deliver specific energy of at least 180 Wh/kg or higher. Testing is being performed at the NASA Glenn Research Center to evaluate the performance of these cells under temperature, rate, and cycling conditions relevant to the ETDP goals for high energy cells. The cell-level specific energy goal for high energy technology is 180 Wh/kg at a C/10 rate and 0 C. The threshold value is 165 Wh/kg. The goal is to operate for at least 2000 cycles at 100 percent DOD with greater than 80 percent capacity retention. The Panasonic NCR18650 cells were able to deliver nearly 200 Wh/kg at the aforementioned conditions. The E-One Moli ICR18650J cells also met the specific energy goal by delivering 183 Wh/kg. Though both cells met the goal for specific energy, this testing was only one portion of the testing required to determine the suitability of commercial cells for the ETDP. The cells must also meet goals for cycle life and safety. The results of this characterization are summarized in this report.

  2. Assessment of commercial prospects of molten carbonate fuel cells

    Science.gov (United States)

    Dicks, Andrew; Siddle, Angie

    The commercial prospects of molten carbonate fuel cells have been evaluated. Market applications, and the commercial criteria that the MCFC will need to satisfy for these applications, were identified through interviews with leading MCFC developers. Strengths, weaknesses, opportunities and threats (SWOT) analyses were carried out to critically evaluate the prospects for commercialisation. There are many competing technologies, but it is anticipated that MCFCs can make significant penetration into markets where their attributes, such as quality of power, low emissions and availability, give them a leading position in comparison with, for example, engine and turbine-based power generation systems. Analysis suggests that choosing the size for MCFC plant is more important than the target market sector/niche. Opportunities will exist in many market sectors, though the commercial market would be easier to penetrate initially. Developers are optimistic about the commercial prospects for the MCFC. Most believe that early commercial MCFC plants may start to appear in the first decade of the next century, the earliest date suggested for initial market entry being 2002.

  3. Electrochemical Energy Storage Technical Team Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    None

    2013-06-01

    This U.S. DRIVE electrochemical energy storage roadmap describes ongoing and planned efforts to develop electrochemical energy storage technologies for plug-in electric vehicles (PEVs). The Energy Storage activity comprises a number of research areas (including advanced materials research, cell level research, battery development, and enabling R&D which includes analysis, testing and other activities) for advanced energy storage technologies (batteries and ultra-capacitors).

  4. Technology Roadmaps: Wind Energy

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-07-01

    Wind energy is perhaps the most advanced of the 'new' renewable energy technologies, but there is still much work to be done. This roadmap identifies the key tasks that must be undertaken in order to achieve a vision of over 2 000 GW of wind energy capacity by 2050. Governments, industry, research institutions and the wider energy sector will need to work together to achieve this goal. Best technology and policy practice must be identified and exchanged with emerging economy partners, to enable the most cost-effective and beneficial development.

  5. Technology Roadmaps: How2Guide for Wind Energy Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2014-03-01

    Whether in OECD, emerging or developing country economies, governments are increasingly looking to diversify their energy mix beyond simply fossil fuels. While wind energy is developing towards a mainstream, competitive and reliable technology, a range of barriers can delay progress, such as financing, grid integration, social acceptance and aspects of planning processes. National and regional technology roadmaps can play a key role in supporting wind energy development and implementation, helping countries to identify priorities and pathways tailored to local resources and markets. Recognising this, the IEA has started the How2Guides - a new series co-ordinated by the International Low-Carbon Energy Technology Platform to address the need for more focused guidance in the development of national roadmaps, or strategies, for specific low-carbon technologies. This builds on the success of the IEA global technology roadmap series and responds to a growing number of requests for IEA guidance to adapt the findings of the IEA global technology roadmaps to national circumstances. A successful roadmap contains a clear statement of the desired outcome, followed by a specific pathway for reaching it. The How2Guide for Wind Energy builds on the IEA well established methodology for roadmap development and shares wind specific recommendations on how to address the four phases to developing and implementing a wind energy roadmap: Planning; Visioning; Development; and Implementation. The manual also offers menus of recommendations on policy and technical options for deployment of utility-scale wind energy installations. A matrix of barriers-versus-realistic solutions options is cross-listed with considerations such as planning, development, electricity market and system, infrastructure, and finance and economics. Drawing on several case studies from around the globe, as well as on the IEA Technology Roadmap for Wind Energy, the How2Guide for Wind Energy it is intended as a

  6. Status of commercial phosphoric acid fuel cell system development

    Science.gov (United States)

    Warshay, M.; Prokopius, P. R.; Simons, S. N.; King, R. B.

    1981-01-01

    A review of the current commercial phosphoric acid fuel cell system development efforts is presented. In both the electric utility and on-site integrated energy system applications, reducing cost and increasing reliability are important. The barrier to the attainment of these goals has been materials. The differences in approach among the three major participants are their technological features, including electrodes, matrices, intercell cooling, bipolar/separator plates, electrolyte management, fuel selection and system design philosophy.

  7. Technology Roadmaps: China Wind Energy Development Roadmap 2050

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    The report shows how China, already the world's largest wind market, could reach 1 000 GW of wind power by the middle of the century, an achievement that would reduce carbon dioxide emissions by 1.5 gigatonnes per year, or roughly equivalent to the combined CO2 emissions of Germany, France and Italy in 2009. The China Wind Energy Roadmap is the first national roadmap that has been developed by a country with IEA support, drawing from its global roadmap series.

  8. Fuel cell commercialization: The key to a hydrogen economy

    Science.gov (United States)

    Zegers, P.

    With the current level of global oil production, oil reserves will be sufficient for 40 years. However, due to the fact that the global GDP will have increased by a factor seven in 2050, oil reserves are likely to be exhausted in a much shorter time period. The EU and car industry aim at a reduction of the consumption of oil, at energy savings (with a key role for fuel cells) and an increased use of hydrogen from natural gas and, possibly, coal, in the medium term. The discovery of huge methane resources as methane hydrates (20 times those of oil, gas and coal together) in oceans at 1000-3000 m depth could be of major importance. In the long term, the EU aims at a renewable energy-based energy supply. The European Hydrogen and Fuel Cell Technology Platform is expected to play a major role in bringing about a hydrogen economy. The availability of commercial fuel cells is here a prerequisite. However, after many years of research, fuel cells have not yet been commercialized. If they will not succeed to enter the market within 5 years there is a real danger that activities aiming at a hydrogen society will peter out. In a hydrogen strategy, high priority should therefore be given to actions which will bring about fuel cell commercialization within 5 years. They should include the identification of fuel cell types and (niche) markets which are most favorable for a rapid market introduction. These actions should include focused short-term RTD aiming at cost reduction and increased reliability.

  9. Power Tower Technology Roadmap and cost reduction plan.

    Energy Technology Data Exchange (ETDEWEB)

    Mancini, Thomas R.; Gary, Jesse A. (U.S. Department of Energy); Kolb, Gregory J.; Ho, Clifford Kuofei

    2011-04-01

    Concentrating solar power (CSP) technologies continue to mature and are being deployed worldwide. Power towers will likely play an essential role in the future development of CSP due to their potential to provide dispatchable solar electricity at a low cost. This Power Tower Technology Roadmap has been developed by the U.S. Department of Energy (DOE) to describe the current technology, the improvement opportunities that exist for the technology, and the specific activities needed to reach the DOE programmatic target of providing competitively-priced electricity in the intermediate and baseload power markets by 2020. As a first step in developing this roadmap, a Power Tower Roadmap Workshop that included the tower industry, national laboratories, and DOE was held in March 2010. A number of technology improvement opportunities (TIOs) were identified at this workshop and separated into four categories associated with power tower subsystems: solar collector field, solar receiver, thermal energy storage, and power block/balance of plant. In this roadmap, the TIOs associated with power tower technologies are identified along with their respective impacts on the cost of delivered electricity. In addition, development timelines and estimated budgets to achieve cost reduction goals are presented. The roadmap does not present a single path for achieving these goals, but rather provides a process for evaluating a set of options from which DOE and industry can select to accelerate power tower R&D, cost reductions, and commercial deployment.

  10. OHVT Technology Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    Bradley, R.A.

    2001-10-22

    The U.S. Department of Energy (DOE) Office of Heavy Vehicle Technologies (OHVT) was created in March 1996 to address the public-interest transportation-energy aspects of a set of customers who at that time had been largely unrecognized, namely, the manufacturers, suppliers, and users of heavy transport vehicles (trucks, buses, rail, and inland marine). Previously, the DOE had focused its attention on meeting the needs of the personal-transport-vehicle customer (automobile manufacturers, suppliers, and users). Those of us who were of driving age at the time of the 1973 oil embargo and the 1979 oil price escalation vividly recall the inconvenience and irritation of having to wait in long lines for gasoline to fuel our cars. However, most of us, other than professional truck owners or drivers, were unaware of the impacts that these disruptions in the fuel supply had on those whose livelihoods depend upon the transport of goods. Recognizing the importance of heavy vehicles to the national economic health, the DOE created OHVT with a mission to conduct, in collaboration with its industry partners and their suppliers, a customer-focused national program to research and develop technologies that will enable trucks and other heavy vehicles to be more energy-efficient and able to use alternative fuels while reducing emissions. The Office of Heavy Vehicle Technologies convened a workshop in April 1996 to elicit input from DOE's heavy vehicle industry customers, including truck and bus manufacturers, diesel-engine manufacturers, fuel producers, suppliers to these industries, and the trucking industry. The preparation of a ''technology roadmap'' was one of the key recommendations by this customer group. Therefore, the OHVT Technology Roadmap* was developed in 1996 as a first step in crafting a common vision for a government research and development (R and D) partnership in this increasingly important transportation sector. The approach used in

  11. Routes to a commercially viable PEM fuel cell stack

    Energy Technology Data Exchange (ETDEWEB)

    Newton, J.; Foster, S.E.; Hodgson, D.; Marrett, A.

    2002-07-01

    This report describes the results of a project to design and build a 10 kW{sub e} proton exchange membrane fuel cell (PEMFC) stack, including membrane electrode assemblies (MEAs), bipolar plates and stack hardware. The aim was to prove the design concept and to demonstrate functionality by operating the stack at >1 kW{sub e}/L and 500 W/kg for 200 hours operation. The project was extended to include the assembly and testing of two additional 1 kW{sub e} PEMFC stacks based on coated metal components. Low equivalent weight perfluorinated ionomer ion exchange membranes were prepared and were found to give a superior electrochemical performance to commercial materials. A technique to etch various stainless steel grades and control processes was successfully developed and optimised. Coatings for stainless steel and titanium were successfully developed and met the required performance criteria. All PEMFC stack components were selected and designed to enable subsequent commercial manufacture.

  12. Technology Roadmaps: Nuclear Energy

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-07-01

    This nuclear energy roadmap has been prepared jointly by the IEA and the OECD Nuclear Energy Agency (NEA). Unlike most other low-carbon energy sources, nuclear energy is a mature technology that has been in use for more than 50 years. The latest designs for nuclear power plants build on this experience to offer enhanced safety and performance, and are ready for wider deployment over the next few years. Several countries are reactivating dormant nuclear programmes, while others are considering nuclear for the first time. China in particular is already embarking on a rapid nuclear expansion. In the longer term, there is great potential for new developments in nuclear energy technology to enhance nuclear's role in a sustainable energy future.

  13. Technology Roadmap: Hydropower

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-07-01

    Hydropower could double its contribution by 2050, reaching 2,000 GW of global capacity and over 7,000 TWh. This achievement, driven primarily by the quest of clean electricity, could prevent annual emissions of up to 3 billion tonnes of CO2 from fossil-fuel plants. The bulk of this growth would come from large plants in emerging economies and developing countries. Hydroelectricity’s many advantages include reliability, proven technology, large storage capacity, and very low operating and maintenance costs. Hydropower is highly flexible, a precious asset for electricity network operators, especially given rapid expansion of variable generation from other renewable energy technologies such as wind power and photovoltaics. Many hydropower plants also provide flood control, irrigation, navigation and freshwater supply. The technology roadmap for Hydropower details action needed from policy makers to allow hydroelectric production to double, and addresses necessary conditions, including resolving environmental issues and gaining public acceptance.

  14. Pathways to Commercial Success. Technologies and Products Supported by the Fuel Cell Technologies Program

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2010-08-01

    This report identifies the commercial and near-commercial (emerging) hydrogen and fuel cell technologies and products that resulted from Department of Energy support through the Fuel Cell Technologies Program in the Office of Energy Efficiency and Renewable Energy.

  15. Roadmap on ultrafast optics

    Science.gov (United States)

    Reid, Derryck T.; Heyl, Christoph M.; Thomson, Robert R.; Trebino, Rick; Steinmeyer, Günter; Fielding, Helen H.; Holzwarth, Ronald; Zhang, Zhigang; Del'Haye, Pascal; Südmeyer, Thomas; Mourou, Gérard; Tajima, Toshiki; Faccio, Daniele; Harren, Frans J. M.; Cerullo, Giulio

    2016-09-01

    The year 2015 marked the 25th anniversary of modern ultrafast optics, since the demonstration of the first Kerr lens modelocked Ti:sapphire laser in 1990 (Spence et al 1990 Conf. on Lasers and Electro-Optics, CLEO, pp 619-20) heralded an explosion of scientific and engineering innovation. The impact of this disruptive technology extended well beyond the previous discipline boundaries of lasers, reaching into biology labs, manufacturing facilities, and even consumer healthcare and electronics. In recognition of such a milestone, this roadmap on Ultrafast Optics draws together articles from some of the key opinion leaders in the field to provide a freeze-frame of the state-of-the-art, while also attempting to forecast the technical and scientific paradigms which will define the field over the next 25 years. While no roadmap can be fully comprehensive, the thirteen articles here reflect the most exciting technical opportunities presented at the current time in Ultrafast Optics. Several articles examine the future landscape for ultrafast light sources, from practical solid-state/fiber lasers and Raman microresonators to exotic attosecond extreme ultraviolet and possibly even zeptosecond x-ray pulses. Others address the control and measurement challenges, requiring radical approaches to harness nonlinear effects such as filamentation and parametric generation, coupled with the question of how to most accurately characterise the field of ultrafast pulses simultaneously in space and time. Applications of ultrafast sources in materials processing, spectroscopy and time-resolved chemistry are also discussed, highlighting the improvements in performance possible by using lasers of higher peak power and repetition rate, or by exploiting the phase stability of emerging new frequency comb sources.

  16. Forest Products Industry Technology Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2010-04-01

    This document describes the forest products industry's research and development priorities. The original technology roadmap published by the industry in 1999 and was most recently updated in April 2010.

  17. Towards stable and commercially available perovskite solar cells

    Energy Technology Data Exchange (ETDEWEB)

    Park, Nam-Gyu; Grätzel, Michael; Miyasaka, Tsutomu; Zhu, Kai; Emery, Keith

    2016-10-17

    Solar cells employing a halide perovskite with an organic cation now show power conversion efficiency of up to 22%. However, these cells are facing issues towards commercialization, such as the need to achieve long-term stability and the development of a manufacturing method for the reproducible fabrication of high-performance devices. Here, we propose a strategy to obtain stable and commercially viable perovskite solar cells. A reproducible manufacturing method is suggested, as well as routes to manage grain boundaries and interfacial charge transport. Electroluminescence is regarded as a metric to gauge theoretical efficiency. We highlight how optimizing the design of device architectures is important not only for achieving high efficiency but also for hysteresis-free and stable performance. We argue that reliable device characterization is needed to ensure the advance of this technology towards practical applications. We believe that perovskite-based devices can be competitive with silicon solar modules, and discuss issues related to the safe management of toxic material.

  18. Towards stable and commercially available perovskite solar cells

    Science.gov (United States)

    Park, Nam-Gyu; Grätzel, Michael; Miyasaka, Tsutomu; Zhu, Kai; Emery, Keith

    2016-11-01

    Solar cells employing a halide perovskite with an organic cation now show power conversion efficiency of up to 22%. However, these cells are facing issues towards commercialization, such as the need to achieve long-term stability and the development of a manufacturing method for the reproducible fabrication of high-performance devices. Here, we propose a strategy to obtain stable and commercially viable perovskite solar cells. A reproducible manufacturing method is suggested, as well as routes to manage grain boundaries and interfacial charge transport. Electroluminescence is regarded as a metric to gauge theoretical efficiency. We highlight how optimizing the design of device architectures is important not only for achieving high efficiency but also for hysteresis-free and stable performance. We argue that reliable device characterization is needed to ensure the advance of this technology towards practical applications. We believe that perovskite-based devices can be competitive with silicon solar modules, and discuss issues related to the safe management of toxic material.

  19. Hydrogen Production Technical Team Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    None

    2013-06-01

    The Hydrogen Production Technical Team Roadmap identifies research pathways leading to hydrogen production technologies that produce near-zero net greenhouse gas (GHG) emissions from highly efficient and diverse renewable energy sources. This roadmap focuses on initial development of the technologies, identifies their gaps and barriers, and describes activities by various U.S. Department of Energy (DOE) offices to address the key issues and challenges.

  20. A European Roadmap for Thermometry

    Science.gov (United States)

    Machin, G.; Bojkovski, J.; del Campo, D.; Dogan, A. K.; Fischer, J.; Hermier, Y.; Merlone, A.; Nielsen, J.; Peruzzi, A.; Ranostaj, J.; Strnad, R.

    2014-04-01

    A technical roadmap for thermometry has been constructed by the EURAMET Technical Committee for Thermometry (TC-T). The roadmap first identified the key triggers that need to be addressed; these included societal grand challenges and the essential scientific metrology to ensure the continued fitness and relevance of the SI unit, the kelvin. In addition, triggers focusing on innovation to support industrial competitiveness such as improvement in product quality and energy efficiency were considered. Clear targets to help address the triggers were formulated; these in turn provide direction to the required temperature measurement research until 2025 and beyond. Although constructed by EURAMET TC-T, the identified societal grand challenges are common within all metrology regions; hence, the roadmap has wider applicability beyond the EURAMET region. A roadmap only ever captures current thinking at the time of formulation, and hence, as with all roadmaps, requires regular revision. For this roadmap this revision will be performed around 2016. This exercise identified that significant research and development were required by the thermometry community if it is to contribute to meet the grand challenges faced by society. The research areas identified here will inform and guide the direction of thermometry research of the national measurement institutes in the EURAMET region over the next decade.

  1. Technology Roadmapping for Waste Management

    Energy Technology Data Exchange (ETDEWEB)

    Bray, O.

    2003-02-26

    Technology roadmapping can be an effective strategic technology planning tool. This paper describes a process for customizing a generic technology roadmapping process. Starting with a generic process reduces the learning curve and speeds up the roadmap development. Similarly, starting with a generic domain model provides leverage across multiple applications or situations within the domain. A process that combines these two approaches facilitates identifying technology gaps and determining common core technologies that can be reused for multiple applications or situations within the domain. This paper describes both of these processes and how they can be integrated. A core team and a number of technology working groups develop the technology roadmap, which includes critical system requirements and targets, technology areas and metrics for each area, and identifies and evaluates possible technology alternatives to recommend the most appropriate ones to pursue. A generalized waste management model, generated by considering multiple situations or applications in terms of a generic waste management model, provides the domain requirements for the technology roadmapping process. Finally, the paper discusses lessons learns from a number of roadmapping projects.

  2. Pseudoislet of hybrid cellular spheroids from commercial cell lines.

    Science.gov (United States)

    Jo, Y H; Nam, B M; Kim, B Y; Nemeno, J G; Lee, S; Yeo, J E; Yang, W; Park, S H; Kim, Y S; Lee, J I

    2013-10-01

    Investigators conducting diabetes-related research have focused on islet transplantation as a radical therapy for type 1 diabetes mellitus. Pancreatic islet isolation, an essential process, is a very demanding work because of the proteolytic enzymes, species, treatment time, and individual difference. Replacement of primary isolated pancreatic islets must be carried out continuously for various in vitro tests, making primary isolated islets a useful tool for cell transplantation research. Hence, we sought to develop pseudoislets from commercial pancreas-derived cell lines. In this study, we used RIN-5F and RIN-m cells, which secrete insulin, somatostatin, or glucagon. To manufacture hybrid cellular spheroids, the cells were cultured under hanging drop plate and nonadhesive plate methods. We observed that hybrid cellular pseudoislets exhibited an oval shape, with sizes ranging from 590 to 1200 μm. Their morphology was similar to naïve islets. Cell line pseudoislets secreted and expressed insulin, glucagon, and somatostatin, as confirmed by reverse transcriptase polymerase chain reaction, enzyme-linked immunosorbent assay, and immunohistochemistry analyses. Thus, the current artificially manufactured biomimetic pseudoislets resembled pancreatic islets of the endocrine system, appearing as cellular aggregates that secreted insulin, glucagon, and somatostatin. Enhanced immunoisolation techniques may lead to the development of new islet sources for pancreatic transplantation through this pseudoislet strategy.

  3. Solar-electric power: The U.S. photovoltaic industry roadmap

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2003-01-01

    To meet this challenge, we — the U.S.-based PV industry — have developed this roadmap as a guide for building our domestic industry, ensuring U.S. technology ownership, and implementing a sound commercialization strategy that will yield significant benefits at minimal cost. Putting the roadmap into action will call for reasonable and consistent co-investment by our industry and government in research and technology development.

  4. A roadmap of cell-type specific gene expression during sequential stages of the arbuscular mycorrhiza symbiosis

    Science.gov (United States)

    2013-01-01

    Background About 80% of today’s land plants are able to establish an arbuscular mycorrhizal (AM) symbiosis with Glomeromycota fungi to improve their access to nutrients and water in the soil. On the molecular level, the development of AM symbioses is only partly understood, due to the asynchronous development of the microsymbionts in the host roots. Although many genes specifically activated during fungal colonization have been identified, genome-wide information on the exact place and time point of their activation remains limited. Results In this study, we relied on a combination of laser-microdissection and the use of Medicago GeneChips to perform a genome-wide analysis of transcription patterns in defined cell-types of Medicago truncatula roots mycorrhized with Glomus intraradices. To cover major stages of AM development, we harvested cells at 5-6 and at 21 days post inoculation (dpi). Early developmental stages of the AM symbiosis were analysed by monitoring gene expression in appressorial and non-appressorial areas from roots harbouring infection units at 5-6 dpi. Here, the use of laser-microdissection for the first time enabled the targeted harvest of those sites, where fungal hyphae first penetrate the root. Circumventing contamination with developing arbuscules, we were able to specifically detect gene expression related to early infection events. To cover the late stages of AM formation, we studied arbusculated cells, cortical cells colonized by intraradical hyphae, and epidermal cells from mature mycorrhizal roots at 21 dpi. Taken together, the cell-specific expression patterns of 18014 genes were revealed, including 1392 genes whose transcription was influenced by mycorrhizal colonization at different stages, namely the pre-contact phase, the infection of roots via fungal appressoria, the subsequent colonization of the cortex by fungal hyphae, and finally the formation of arbuscules. Our cellular expression patterns identified distinct groups of AM

  5. Roadmap on optical metamaterials

    Science.gov (United States)

    Urbas, Augustine M.; Jacob, Zubin; Dal Negro, Luca; Engheta, Nader; Boardman, A. D.; Egan, P.; Khanikaev, Alexander B.; Menon, Vinod; Ferrera, Marcello; Kinsey, Nathaniel; DeVault, Clayton; Kim, Jongbum; Shalaev, Vladimir; Boltasseva, Alexandra; Valentine, Jason; Pfeiffer, Carl; Grbic, Anthony; Narimanov, Evgenii; Zhu, Linxiao; Fan, Shanhui; Alù, Andrea; Poutrina, Ekaterina; Litchinitser, Natalia M.; Noginov, Mikhail A.; MacDonald, Kevin F.; Plum, Eric; Liu, Xiaoying; Nealey, Paul F.; Kagan, Cherie R.; Murray, Christopher B.; Pawlak, Dorota A.; Smolyaninov, Igor I.; Smolyaninova, Vera N.; Chanda, Debashis

    2016-09-01

    Optical metamaterials have redefined how we understand light in notable ways: from strong response to optical magnetic fields, negative refraction, fast and slow light propagation in zero index and trapping structures, to flat, thin and perfect lenses. Many rules of thumb regarding optics, such as μ = 1, now have an exception, and basic formulas, such as the Fresnel equations, have been expanded. The field of metamaterials has developed strongly over the past two decades. Leveraging structured materials systems to generate tailored response to a stimulus, it has grown to encompass research in optics, electromagnetics, acoustics and, increasingly, novel hybrid material responses. This roadmap is an effort to present emerging fronts in areas of optical metamaterials that could contribute and apply to other research communities. By anchoring each contribution in current work and prospectively discussing future potential and directions, the authors are translating the work of the field in selected areas to a wider community and offering an incentive for outside researchers to engage our community where solid links do not already exist.

  6. Technology Roadmap: Energy Storage

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2014-03-01

    Energy storage technologies are valuable components in most energy systems and could be an important tool in achieving a low-carbon future. These technologies allow for the decoupling of energy supply and demand, in essence providing a valuable resource to system operators. There are many cases where energy storage deployment is competitive or near-competitive in today's energy system. However, regulatory and market conditions are frequently ill-equipped to compensate storage for the suite of services that it can provide. Furthermore, some technologies are still too expensive relative to other competing technologies (e.g. flexible generation and new transmission lines in electricity systems). One of the key goals of this new roadmap is to understand and communicate the value of energy storage to energy system stakeholders. This will include concepts that address the current status of deployment and predicted evolution in the context of current and future energy system needs by using a ''systems perspective'' rather than looking at storage technologies in isolation.

  7. Catalyst technology roadmap report

    Energy Technology Data Exchange (ETDEWEB)

    Jackson, N.B.

    1997-06-01

    This report outlines the future technology needs of the Chemical Industry in the area of catalysis and is a continuation of the process that produced the report Technology Vision 2020: The U.S. Chemical Industry and the Council for Chemical Research`s (CCR) Chemical Synthesis Team follow-up work in chemical synthesis. Vision 2020 developed a 25-year vision for the chemical industry and outlined the challenges to be addressed in order to achieve this vision. This report, which outlines the catalysis technology roadmap, is based on the output of the CCR`s Chemical Synthesis Team, plus a workshop held March -20-21, 1997, which included about 50 participants, with catalysis experts from industry, academia, and government. It is clear that all participants view catalysis as a fundamental driver to the 0274 economic and environmental viability of the chemical industry. Advances in catalytic science and technology are among the most crucial challenges to achieving the goals of the chemical industry advanced in Vision 2020.

  8. Concentrating Solar Power. Technology Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-10-15

    Concentrating solar power can contribute significantly to the world's energy supply. As shown in this roadmap, this decade is a critical window of opportunity during which CSP could become a competitive source of electrical power to meet peak and intermediate loads in the sunniest parts of the world. This roadmap identifies technology, economy and policy goals and milestones needed to support the development and deployment of CSP, as well as ongoing advanced research in CSF. It also sets out the need for governments to implement strong, balanced policies that favour rapid technological progress, cost reductions and expanded industrial manufacturing of CSP equipment to enable mass deployment. Importantly, this roadmap also establishes a foundation for greater international collaboration. The overall aim of this roadmap is to identify actions required - on the part of all stakeholders - to accelerate CSP deployment globally. Many countries, particularly in emerging regions, are only just beginning to develop CSP. Accordingly, milestone dates should be considered as indicative of urgency, rather than as absolutes. This roadmap is a work in progress. As global CSP efforts advance and an increasing number of CSP applications are developed, new data will provide the basis for updated analysis. The IEA will continue to track the evolution of CSP technology and its impacts on markets, the power sector and regulatory environments, and will update its analysis and set additional tasks and milestones as new learning comes to light.

  9. The GRIP method for collaborative roadmapping workshops

    DEFF Research Database (Denmark)

    Piirainen, Kalle

    2015-01-01

    Technology roadmapping is a well-known tool for technology management, but practical advice for facilitating collaborative roadmapping workshops is relatively scarce. To cater for this need, we have designed a method for collaborative roadmapping, dubbed the GRIP method, for facilitating group work...

  10. A Technology Roadmap for Strategic Development of Enhanced Geothermal Systems

    Energy Technology Data Exchange (ETDEWEB)

    Ziagos, John [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Phillips, Benjamin R. [SRA International, Inc. and Geothermal Technologies Office, Washington, DC (United States); Boyd, Lauren [Geothermal Technologies Office, Washington, DC (United States); Jelacic, Allan [SRA International, Inc., Washington, DC (United States); Stillman, Greg [Geothermal Technologies Office, Washington, DC (United States); Hass, Eric [U.S. DOE, Golden, CO (United States)

    2013-02-13

    Realization of EGS development would make geothermal a significant contender in the renewable energy portfolio, on the order of 100+ GWe in the United States alone. While up to 90% of the geothermal power resource in the United States is thought to reside in Enhanced Geothermal Systems (EGS), hurdles to commercial development still remain. The Geothermal Technologies Office, U.S. Department of Energy (DOE), began in 2011 to outline opportunities for advancing EGS technologies on five- to 20-year timescales, with community input on the underlying technology needs that will guide research and ultimately determine commercial success for EGS. This report traces DOE's research investments, past and present, and ties them to these technology needs, forming the basis for an EGS Technology Roadmap to help guide future DOE research. This roadmap is currently open for public comment. Send your comments to geothermal@ee.doe.gov.

  11. Commercial Development Of Ovonic Thin Film Solar Cells

    Science.gov (United States)

    Ovshinsky, Stanford R.

    1983-09-01

    One square foot Ovonic amorphous photovoltaic devices are already in commercial production and are manufactured through a continuous web process. The next levels of commercialization required to achieve a large-volume power market will be discussed, and the device specifications correlated with the chemical and electronic properties of the materials that we are developing to achieve even higher efficiencies. It has been long considered a utopian dream to harness the energy of the sun to create electricity that would be competitive in cost to that produced from the conventional sources of energy such as oil, gas, and uranium. The impact on our society of stand-alone power generators without moving parts using the continually available, ubiquitous energy of the sun could certainly lead to a new age with consequences comparable to the first introduction of electricity which greatly accelerated the Industrial Revolution. Low cost, nonpolluting energy not dependent upon or limited by transmission costs could again make DC electricity a realistic option. The relatively young field of photovoltaics suffers from certain dogmas that are just now being questioned. For example, it is thought by many that solar cells utilizing crys-talline materials have inherently higher efficiencies than those using amorphous materials, and that somehow crystalline solar cells, whether fabricated from single crystals or polycrystalline material, in round or rectangular geometries, grown from the melt or by a rib-bon process, can be reduced in cost sufficiently that the economics become attractive enough for large-scale terrestrial generation of power. In this paper, we shall show that amorphous materials can have much higher efficiencies than do crystalline and that the answer to our power generation needs lies not in crystalline but in amorphous technology. At Energy Conversion Devices, Inc. (ECD), we have designed and built a production machine (described by my colleague, Dr. Izu, in a

  12. Roadmap on silicon photonics

    Science.gov (United States)

    Thomson, David; Zilkie, Aaron; Bowers, John E.; Komljenovic, Tin; Reed, Graham T.; Vivien, Laurent; Marris-Morini, Delphine; Cassan, Eric; Virot, Léopold; Fédéli, Jean-Marc; Hartmann, Jean-Michel; Schmid, Jens H.; Xu, Dan-Xia; Boeuf, Frédéric; O'Brien, Peter; Mashanovich, Goran Z.; Nedeljkovic, M.

    2016-07-01

    Silicon photonics research can be dated back to the 1980s. However, the previous decade has witnessed an explosive growth in the field. Silicon photonics is a disruptive technology that is poised to revolutionize a number of application areas, for example, data centers, high-performance computing and sensing. The key driving force behind silicon photonics is the ability to use CMOS-like fabrication resulting in high-volume production at low cost. This is a key enabling factor for bringing photonics to a range of technology areas where the costs of implementation using traditional photonic elements such as those used for the telecommunications industry would be prohibitive. Silicon does however have a number of shortcomings as a photonic material. In its basic form it is not an ideal material in which to produce light sources, optical modulators or photodetectors for example. A wealth of research effort from both academia and industry in recent years has fueled the demonstration of multiple solutions to these and other problems, and as time progresses new approaches are increasingly being conceived. It is clear that silicon photonics has a bright future. However, with a growing number of approaches available, what will the silicon photonic integrated circuit of the future look like? This roadmap on silicon photonics delves into the different technology and application areas of the field giving an insight into the state-of-the-art as well as current and future challenges faced by researchers worldwide. Contributions authored by experts from both industry and academia provide an overview and outlook for the silicon waveguide platform, optical sources, optical modulators, photodetectors, integration approaches, packaging, applications of silicon photonics and approaches required to satisfy applications at mid-infrared wavelengths. Advances in science and technology required to meet challenges faced by the field in each of these areas are also addressed together with

  13. Biogas Opportunities Roadmap Progress Report

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2015-12-01

    In support of the Obama Administration's Climate Action Plan, the U.S. Department of Energy, the U.S. Environmental Protection Agency, and U.S. Department of Agriculture jointly released the Biogas Opportunities Roadmap Progress Report, updating the federal government's progress to reduce methane emissions through biogas systems since the Biogas Opportunities Roadmap was completed by the three agencies in July 2014. The report highlights actions taken, outlines challenges and opportunities, and identifies next steps to the growth of a robust biogas industry.

  14. Technology Roadmaps: Biofuels for Transport

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    Biofuels could provide up to 27% of total transport fuel worldwide by 2050. The use of transport fuels from biomass, when produced sustainably, can help cut petroleum use and reduce CO2 emissions in the transport sector, especially in heavy transport. Sustainable biofuel technologies, in particular advanced biofuels, will play an important role in achieving this roadmap vision. The roadmap describes the steps necessary to realise this ambitious biofuels target; identifies key actions by different stakeholders, and the role for government policy to adopt measures needed to ensure the sustainable expansion of both conventional and advanced biofuel production.

  15. Partnership for Wave Power - Roadmaps

    DEFF Research Database (Denmark)

    Nielsen, Kim; Krogh, Jan; Brodersen, Hans Jørgen;

    This Wave Energy Technology Roadmap is developed by the Partnership for Wave Power including nine Danish wave energy developers. It builds on to the strategy [1] published by the Partnership in 2012, a document that describes the long term vision of the Danish Wave Energy sector: “By 2030...

  16. Electronic Safety Resource Tools -- Supporting Hydrogen and Fuel Cell Commercialization

    Energy Technology Data Exchange (ETDEWEB)

    Barilo, Nick F.

    2014-09-29

    The Pacific Northwest National Laboratory (PNNL) Hydrogen Safety Program conducted a planning session in Los Angeles, CA on April 1, 2014 to consider what electronic safety tools would benefit the next phase of hydrogen and fuel cell commercialization. A diverse, 20-person team led by an experienced facilitator considered the question as it applied to the eight most relevant user groups. The results and subsequent evaluation activities revealed several possible resource tools that could greatly benefit users. The tool identified as having the greatest potential for impact is a hydrogen safety portal, which can be the central location for integrating and disseminating safety information (including most of the tools identified in this report). Such a tool can provide credible and reliable information from a trustworthy source. Other impactful tools identified include a codes and standards wizard to guide users through a series of questions relating to application and specific features of the requirements; a scenario-based virtual reality training for first responders; peer networking tools to bring users from focused groups together to discuss and collaborate on hydrogen safety issues; and a focused tool for training inspectors. Table ES.1 provides results of the planning session, including proposed new tools and changes to existing tools.

  17. Roadmap on optical security

    NARCIS (Netherlands)

    javidi, B.; Carnicer, A.; Yamaguchi, M.; Nomura, T.; Pérez-Cabré, E.; Millan, M.S.; Nishchal, N.K.; Torroba, R.; Barrera, J.F.; He, W.; Peng, X.; Stern, A.; Rivenson, Y.; Alfalou, A.; Brosseau, C.; Guo, C.; Sheridan, J.T.; Situ, G.; Naruse, M.; Matsumoto, T.; Juvells, I.; Tajahuerce, E.; Lancis, J.; Chen, W.; Chen, X.; Pinkse, P.W.H.; Mosk, A.P.; Markman, A.

    2016-01-01

    Information security and authentication are important challenges facing society. Recent attacks by hackers on the databases of large commercial and financial companies have demonstrated that more research and development of advanced approaches are necessary to deny unauthorized access to critical da

  18. Roadmap on optical securit

    NARCIS (Netherlands)

    javidi, B.; Carnicer, A.; Yamaguchi, M.; Nomura, T.; Pérez-Cabré, E.; Millan, M.S.; Nishchal, N.K.; Torroba, R.; Barrera, J.F.; He, W.; Peng, X.; Stern, A.; Rivenson, Y.; Alfalou, A.; Brosseau, C.; Guo, C.; Sheridan, J.T.; Situ, G.; Naruse, M.; Matsumoto, T.; Juvells, I.; Tajahuerce, E.; Lancis, J.; Chen, W.; Chen, X.; Pinkse, P.W.H.; Mosk, A.P.; Markman, A.

    2016-01-01

    Information security and authentication are important challenges facing society. Recent attacks by hackers on the databases of large commercial and financial companies have demonstrated that more research and development of advanced approaches are necessary to deny unauthorized access to critical da

  19. Roadmap for H{sub 2} in the Nordic Countries

    Energy Technology Data Exchange (ETDEWEB)

    Dannemand Andersen, P.; Greve, O.K.; Kruger Nielsen, S.

    2004-12-01

    This report reports on a roadmap workshop held in Roskilde in 2004 as part of the Nordic H{sub 2} Energy Foresight project. The workshop outlined a sequence of implementation and mutual interdependence of the hydrogen technology visions from today (2004) and until 2030. Furthermore, barriers, needs and drivers for realising the visions were discussed at the workshop in relation to science an education (needs for scientific research, needs for competences) and government (energy and industry policy, public R and D, early market stimulation, standardisation, safety). The roadmaps outlined key issues and challenges in hydrogen and fuel cell energy development and suggested paths that Nordic industry, energy companies, academia and governments may take to expand the use of hydrogen and fuel cell-based energy. Roadmap exercises offer a collective and consultative process, with the processes itself being equally important as the outcome. Hence, the aim is not to predict or suggest exact targets for hydrogen in the Nordic countries by 2030 nor putting up exact ways to achieve these targets. Bur by setting up ambitious and realistic targets and putting up roadmaps we can challenge our understanding of a future hydrogen society and be better able to suggest policies and decisions today. (au)

  20. Unmanned Ground Systems Roadmap

    Science.gov (United States)

    2011-07-01

    Squad Mission Support System SOC .............................. Special Operations Command SOFC ............................ Solid Oxide Fuel Cell ...technologies may be used to match a given Use Profile: Table 5. Power Use Profiles Energy Storage Energy Harvesting Fuel Cells Engines Lead Acid...significant amount of research and development in both Government and Industry have been devoted to the areas of energy storage, fuel cells , and small

  1. Pathways to Commercial Success: Technologies and Products Supported by the Fuel Cell Technologies Office - 2015

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2016-01-08

    This FY 2015 report updates the results of an effort to identify and document the commercial and emerging (projected to be commercialized within the next 3 to 5 years) hydrogen and fuel cell technologies and products that resulted from U.S. Department of Energy support through the Fuel Cell Technologies Office in the Office of Energy Efficiency and Renewable Energy.

  2. Current legal and institutional issues in the commercialization of phosphoric acid fuel cells

    Science.gov (United States)

    Nimmons, J. T.; Sheehy, K. D.; Singer, J. R.; Gardner, T. C.

    1982-01-01

    Legal and institutional factors affecting the development and commercial diffusion of phosphoric acid fuel cells are assessed. Issues for future research and action are suggested. Perceived barriers and potential opportunities for fuel cells in central and dispersed utility operations and on-site applications are reviewed, as well as the general concept of commercialization as applied to emerging energy technologies.

  3. Concentrating Solar Power Gen3 Demonstration Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    Mehos, Mark [National Renewable Energy Lab. (NREL), Golden, CO (United States); Turchi, Craig [National Renewable Energy Lab. (NREL), Golden, CO (United States); Vidal, Judith [National Renewable Energy Lab. (NREL), Golden, CO (United States); Wagner, Michael [National Renewable Energy Lab. (NREL), Golden, CO (United States); Ma, Zhiwen [National Renewable Energy Lab. (NREL), Golden, CO (United States); Ho, Clifford [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Kolb, William [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Andraka, Charles [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Kruizenga, Alan [Sandia National Lab. (SNL-CA), Livermore, CA (United States)

    2017-01-01

    Today's power-tower concentrating solar power (CSP) technology exists in large part as a result of Department of Energy (DOE) and utility industry funding of demonstration systems in the 1980s and 1990s. Today's most advanced towers are integrated with molten-salt thermal energy storage, delivering thermal energy at 565 degrees C for integration with conventional steam-Rankine cycles. The supercritical carbon dioxide power cycle has been identified as a likely successor to the steam-Rankine power cycle due to its potential for high efficiency when operating at elevated temperatures of 700 degrees C or greater. Over the course of the SunShot Initiative, DOE has supported a number of technology pathways that can operate efficiently at these temperatures and that hold promise to be reliable and cost effective. Three pathways - molten salt, particle, and gaseous - were selected for further investigation based on a two-day workshop held in August of 2016. The information contained in this roadmap identifies research and development challenges and lays out recommended research activities for each of the three pathways. DOE foresees that by successfully addressing the challenges identified in this roadmap, one or more technology pathways will be positioned for demonstration and subsequent commercialization within the next ten years. Based on current knowledge of the three power tower technologies, all three have the potential to achieve the SunShot goal of 6 cents/kilowatt-hour. Further development, modeling, and testing are now required to bring one or more of the technologies to a stage where integrated system tests and pilot demonstrations are feasible.

  4. Interactions between grape skin cell wall material and commercial enological tannins. Practical implications.

    Science.gov (United States)

    Bautista-Ortín, Ana Belén; Cano-Lechuga, Mario; Ruiz-García, Yolanda; Gómez-Plaza, Encarna

    2014-01-01

    Commercial enological tannins were used to investigate the role that cell wall material plays in proanthocyanidin adsorption. Insoluble cell wall material, prepared from the skin of Vitis vinifera L. cv. Monastrell berries, was combined with solutions containing six different commercial enological tannins (proanthocyanidin-type tannins). Analysis of the proanthocyanidins in the solution, after fining with cell wall material, using phloroglucinolysis and size exclusion chromatography, provided quantitative and qualitative information on the non-adsorbed compounds. Cell wall material showed strong affinity for the proanthocyanidins, one of the commercial tannins being bound up to 61% in the experiment. Comparison of the molecular mass distribution of the commercial enological tannins in solution, before and after fining, suggested that cell walls affinity for proanthocyanidins was more related with the proanthocyanidin molecular mass than with their percentage of galloylation. These interactions may have some enological implications, especially as regards the time of commercial tannins addition to the must/wine.

  5. Hanford Site Secondary Waste Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    Westsik, Joseph H.

    2009-01-29

    Summary The U.S. Department of Energy (DOE) is making plans to dispose of 54 million gallons of radioactive tank wastes at the Hanford Site near Richland, Washington. The high-level wastes and low-activity wastes will be vitrified and placed in permanent disposal sites. Processing of the tank wastes will generate secondary wastes, including routine solid wastes and liquid process effluents, and these need to be processed and disposed of also. The Department of Energy Office of Waste Processing sponsored a meeting to develop a roadmap to outline the steps necessary to design the secondary waste forms. Representatives from DOE, the U.S. Environmental Protection Agency, the Washington State Department of Ecology, the Oregon Department of Energy, Nuclear Regulatory Commission, technical experts from the DOE national laboratories, academia, and private consultants convened in Richland, Washington, during the week of July 21-23, 2008, to participate in a workshop to identify the risks and uncertainties associated with the treatment and disposal of the secondary wastes and to develop a roadmap for addressing those risks and uncertainties. This report describes the results of the roadmap meeting in Richland. Processing of the tank wastes will generate secondary wastes, including routine solid wastes and liquid process effluents. The secondary waste roadmap workshop focused on the waste streams that contained the largest fractions of the 129I and 99Tc that the Integrated Disposal Facility risk assessment analyses were showing to have the largest contribution to the estimated IDF disposal impacts to groundwater. Thus, the roadmapping effort was to focus on the scrubber/off-gas treatment liquids with 99Tc to be sent to the Effluent Treatment Facility for treatment and solidification and the silver mordenite and carbon beds with the captured 129I to be packaged and sent to the IDF. At the highest level, the secondary waste roadmap includes elements addressing regulatory and

  6. Thermally activated technologies: Technology Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2003-05-01

    The purpose of this Technology Roadmap is to outline a set of actions for government and industry to develop thermally activated technologies for converting America’s wasted heat resources into a reservoir of pollution-free energy for electric power, heating, cooling, refrigeration, and humidity control. Fuel flexibility is important. The actions also cover thermally activated technologies that use fossil fuels, biomass, and ultimately hydrogen, along with waste heat.

  7. Technology Roadmaps: Energy-efficient Buildings: Heating and Cooling Equipment

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    Buildings account for almost a third of final energy consumption globally and are an equally important source of CO2 emissions. Currently, both space heating and cooling as well as hot water are estimated to account for roughly half of global energy consumption in buildings. Energy-efficient and low/zero-carbon heating and cooling technologies for buildings have the potential to reduce CO2 emissions by up to 2 gigatonnes (Gt) and save 710 million tonnes oil equivalent (Mtoe) of energy by 2050. Most of these technologies -- which include solar thermal, combined heat and power (CHP), heat pumps and thermal energy storage -- are commercially available today. The Energy-Efficient Buildings: Heating and Cooling Equipment Roadmap sets out a detailed pathway for the evolution and deployment of the key underlying technologies. It finds that urgent action is required if the building stock of the future is to consume less energy and result in lower CO2 emissions. The roadmap concludes with a set of near-term actions that stakeholders will need to take to achieve the roadmap's vision.

  8. Cell Attachment of Periodontal Ligament Cells on Commercially Pure Titanium at the Early Stage

    Institute of Scientific and Technical Information of China (English)

    周彬; 曹颖光; 吴丽娟; 袁艳祥; 曾引萍

    2004-01-01

    Summary: In order to study the character of periodontal ligament cells (PDLCs) attaching on commercially pure titanium (cpTi) by morphology and metrology on the early stage (24 h), 1×105/ml PDLCs in 2 ml culture medium were seeded on cpTi discs fixed in 24-well culture plates. Morphology of cell attachment was observed by contrast phase microscope, scanning electron microscope (SEM) and fluroscence microscopy. Cell adhesion was analyzed by MTT at 0.5, 1, 2, 4 h respectively. PDLCs could attach and spread on cpTi discs. SEM showed that PDLCs had pseudopod-like protuberance. PDLCs showed different attaching phases and reached saturation in cell number at 2 h. It was concluded that PDLCs had good biocompatibility with cpTi, and showed a regular and dynamic pattern in the process of attaching to cpTi.

  9. The 2017 terahertz science and technology roadmap

    Science.gov (United States)

    Dhillon, S. S.; Vitiello, M. S.; Linfield, E. H.; Davies, A. G.; Hoffmann, Matthias C.; Booske, John; Paoloni, Claudio; Gensch, M.; Weightman, P.; Williams, G. P.; Castro-Camus, E.; Cumming, D. R. S.; Simoens, F.; Escorcia-Carranza, I.; Grant, J.; Lucyszyn, Stepan; Kuwata-Gonokami, Makoto; Konishi, Kuniaki; Koch, Martin; Schmuttenmaer, Charles A.; Cocker, Tyler L.; Huber, Rupert; Markelz, A. G.; Taylor, Z. D.; Wallace, Vincent P.; Axel Zeitler, J.; Sibik, Juraj; Korter, Timothy M.; Ellison, B.; Rea, S.; Goldsmith, P.; Cooper, Ken B.; Appleby, Roger; Pardo, D.; Huggard, P. G.; Krozer, V.; Shams, Haymen; Fice, Martyn; Renaud, Cyril; Seeds, Alwyn; Stöhr, Andreas; Naftaly, Mira; Ridler, Nick; Clarke, Roland; Cunningham, John E.; Johnston, Michael B.

    2017-02-01

    Science and technologies based on terahertz frequency electromagnetic radiation (100 GHz-30 THz) have developed rapidly over the last 30 years. For most of the 20th Century, terahertz radiation, then referred to as sub-millimeter wave or far-infrared radiation, was mainly utilized by astronomers and some spectroscopists. Following the development of laser based terahertz time-domain spectroscopy in the 1980s and 1990s the field of THz science and technology expanded rapidly, to the extent that it now touches many areas from fundamental science to ‘real world’ applications. For example THz radiation is being used to optimize materials for new solar cells, and may also be a key technology for the next generation of airport security scanners. While the field was emerging it was possible to keep track of all new developments, however now the field has grown so much that it is increasingly difficult to follow the diverse range of new discoveries and applications that are appearing. At this point in time, when the field of THz science and technology is moving from an emerging to a more established and interdisciplinary field, it is apt to present a roadmap to help identify the breadth and future directions of the field. The aim of this roadmap is to present a snapshot of the present state of THz science and technology in 2017, and provide an opinion on the challenges and opportunities that the future holds. To be able to achieve this aim, we have invited a group of international experts to write 18 sections that cover most of the key areas of THz science and technology. We hope that The 2017 Roadmap on THz science and technology will prove to be a useful resource by providing a wide ranging introduction to the capabilities of THz radiation for those outside or just entering the field as well as providing perspective and breadth for those who are well established. We also feel that this review should serve as a useful guide for government and funding agencies.

  10. Roadmap for Process Equipment Materials Technology

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2003-10-01

    This Technology Roadmap addresses the ever-changing material needs of the chemical and allied process industries, and the energy, economic and environmental burdens associated with corrosion and other materials performance and lifetime issues. This Technology Roadmap outlines the most critical of these R&D needs, and how they can impact the challenges facing today’s materials of construction.

  11. Pathways to Commercial Success: Technologies and Products Supported by the Fuel Cell Technologies Office - 2013

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2014-04-30

    This FY 2013 report updates the results of an effort to identify and characterize commercial and near-commercial (emerging) technologies and products that benefited from the support of the Fuel Cell Technologies Office and its predecessor programs within DOE's Office of Energy Efficiency and Renewable Energy.

  12. Pathways to Commercial Success: Technologies and Products Supported by the Fuel Cell Technologies Office - 2014

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2015-02-01

    This FY 2014 report updates the results of an effort to identify and characterize commercial and near-commercial (emerging) technologies and products that benefited from the support of the Fuel Cell Technologies Office and its predecessor programs within DOE's Office of Energy Efficiency and Renewable Energy.

  13. Pathways to Commercial Success. Technologies and Products Supported by the Fuel Cell Technologies Program

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2011-09-01

    This FY 2011 report updates the results of an effort to identify and characterize commercial and near-commercial (emerging) technologies and products that benefited from the support of the Fuel Cell Technologies Program and its predecessor programs within DOE's Office of Energy Efficiency and Renewable Energy.

  14. Pathways to Commercial Success. Technologies and Products Supported by the Fuel Cell Technologies Program - 2012

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2012-09-01

    This FY 2012 report updates the results of an effort to identify and characterize commercial and near-commercial (emerging) technologies and products that benefited from the support of the Fuel Cell Technologies Program and its predecessor programs within DOE's Office of Energy Efficiency and Renewable Energy.

  15. Perovskite solar cells: On top of commercial photovoltaics

    Science.gov (United States)

    Albrecht, Steve; Rech, Bernd

    2017-01-01

    The efficiency of single-junction solar cells is intrinsically limited and high efficiency multi-junctions are not cost effective yet. Now, semi-transparent perovskite solar cells suggest that low cost multi-junctions could be within reach.

  16. Vision 2020. Reaction Engineering Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    Klipstein, David H. [Reaction Design, San Diego, CA (United States); Robinson, Sharon [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2001-01-01

    The Reaction Engineering Roadmap is a part of an industry- wide effort to create a blueprint of the research and technology milestones that are necessary to achieve longterm industry goals. This report documents the results of a workshop focused on the research needs, technology barriers, and priorities of the chemical industry as they relate to reaction engineering viewed first by industrial use (basic chemicals; specialty chemicals; pharmaceuticals; and polymers) and then by technology segment (reactor system selection, design, and scale-up; chemical mechanism development and property estimation; dealing with catalysis; and new, nonstandard reactor types).

  17. Fuel cell commercialization issues for light-duty vehicle applications

    Science.gov (United States)

    Borroni-Bird, Christopher E.

    The major challenges facing fuel cells in light-duty vehicle applications relate to the high cost of the fuel cell stack components (membrane, electro-catalyst and bipolar plate) which dictate that new manufacturing processes and materials must be developed. Initially, the best fuel for a mass market light-duty vehicle will probably not be the best fuel for the fuel cell (hydrogen); refueling infrastructure and energy density concerns may demand the use of an on-board fuel processor for petroleum-based fuels since this will increase customer acceptance. The use of fuel processors does, however, reduce the fuel cell system's efficiency. Moreover, if such fuels are used then the emissions benefit associated with fuel cells may come with a significant penalty in terms of added complexity, weight, size and cost. However, ultimately, fuel cells powered by hydrogen do promise to be the most efficient and cleanest of automotive powertrains.

  18. High-Efficiency, Commercial Ready CdTe Solar Cells

    Energy Technology Data Exchange (ETDEWEB)

    Sites, James R. [Colorado State Univ., Fort Collins, CO (United States)

    2015-11-19

    Colorado State’s F-PACE project explored several ways to increase the efficiency of CdTe solar cells and to better understand the device physics of those cells under study. Increases in voltage, current, and fill factor resulted in efficiencies above 17%. The three project tasks and additional studies are described in detail in the final report. Most cells studied were fabricated at Colorado State using an industry-compatible single-vacuum closed-space-sublimation (CSS) chamber for deposition of the key semiconductor layers. Additionally, some cells were supplied by First Solar for comparison purposes, and a small number of modules were supplied by Abound Solar.

  19. Fuel cell transit bus development & commercialization programs at Gerogetown University

    Energy Technology Data Exchange (ETDEWEB)

    Wimmer, R.; Larkins, J.; Romano, S. [Georgetown Univ., Washington, DC (United States)

    1996-12-31

    Fourteen years ago, Georgetown University (GU) perceived the need for a clean, efficient power systems for transportation that could operate on non-petroleum based fuels. The transit bus application was selected to begin system development. GU recognized the range and recharge constraints of a pure battery powered transit bus. A Fuel Cell power system would circumvent these limitations and, with an on board reformer, accommodate liquid fuel for rapid refueling. Feasibility studies for Fuel Cell power systems for transit buses were conducted with the Los Alamos National Laboratory in 1983. Successful results of this investigation resulted in the DOT/DOE Fuel Cell transit bus development program. The first task was to prove that small Fuel Cell power plants were possible. This was achieved with the Phase I development of two 25 kW Phosphoric Acid Fuel Cell (PAFC) brassboard systems. A liquid cooled version was selected for the Phase II activity in which three 30-foot Fuel Cell powered Test Bed Buses (TBBs) were fabricated. The first of these TBBs was delivered in the spring of 1994. All three of these development vehicles are now in Phase III of the program to conduct testing and evaluation, is conducting operational testing of the buses. The test will involve two fuel cell-operated buses; one with a proton exchange fuel cell and the other with a phosphoric acid fuel cell.

  20. China's bioenergy industry development roadmap

    Institute of Scientific and Technical Information of China (English)

    Shi Yuanchun; Li Shizhong; Liu Xuejun

    2009-01-01

    Positive development of renewable energy, saving and substitution of fossil energy, promotion of the energy structure adjustment are the inevitable strategy choices of China's sustainable development. This paper discussed the China's bioenergy resources status, development targets and technology development roadmaps. China has 136. 140 million hm2 of marginal land, which distribute mainly in western and northern regions. There are 1 billion t of crop resi-dues and forestry waste annually, and 300 million t can be used to produce different kinds of bioenergies. And organic waste and manure can generate 50 billion m3 of biogas. The discussed development target indicated that it can construct a biomass oilfield with the capacity of 100 million t/year and reduce 200 million t of CO2 emission by 2020. The bioen-ergy technology development roadmap indicated that the bioethanol mainly uses non grain starch and hemicellulose prod-ucts as raw materials in the near-term (2006- 2010). The biodiesel technology will focus on the advanced production technology, FT diesel, liquefaction of biomass and raw material production technology.

  1. Advances in stem cells technologies and their commercialization potential.

    Science.gov (United States)

    Kamarul, Tunku

    2013-07-01

    The World Stem Cells & Regenerative Medicine Congress Asia 2013 held in Singapore from 19-21 March 2013 was attended by over 2000 industry attendees and 5000 registered visitors. The focus of the congress was to discuss potential uses of stem cells for various diagnostic and therapeutic applications, their market opportunity and the latest R&D, which would potentially find its way into the market in not too distant future. In addition to the traditional lectures presented by academic and industry experts, there were forums, discussions, posters and exhibits, which provided various platforms for researchers, potential industry partners and even various interest groups to discuss prospective development of the stem cell-related industry.

  2. Commercialization of proton exchange membrane fuel cells for transportation applications

    Energy Technology Data Exchange (ETDEWEB)

    Wismer, L.

    1996-04-01

    Environmental concerns with air quality and global warming have triggered strict federal ambient ozone air quality standards. Areas on non-attainment of these standards exist across the United States. Because it contains several of the most difficult attainment areas, the State of California has adopted low emission standards including a zero emission vehicle mandate that has given rise to development of hybrid electric vehicles, both battery-powered and fuel-cell powered. Fuel cell powered vehicles, using on-board hydrogen as a fuel, share the non-polluting advantage of the battery electric vehicle while offering at least three times the range today`s battery technology.

  3. Stem cell research funding policies and dynamic innovation: a survey of open access and commercialization requirements.

    Science.gov (United States)

    Lévesque, Maroussia; Kim, Jihyun Rosel; Isasi, Rosario; Knoppers, Bartha Maria; Plomer, Aurora; Joly, Yann

    2014-08-01

    This article compares and contrasts the pressures of both open access data sharing and commercialization policies in the context of publicly funded embryonic stem cell research (SCR). First, normative guidelines of international SCR organizations were examined. We then examined SCR funding guidelines and the project evaluation criteria of major funding organizations in the EU, the United Kingdom (UK), Spain, Canada and the United States. Our survey of policies revealed subtle pressures to commercialize research that include: increased funding availability for commercialization opportunities, assistance for obtaining intellectual property rights (IPRs) and legislation mandating commercialization. In lieu of open access models, funders are increasingly opting for limited sharing models or "protected commons" models that make the research available to researchers within the same region or those receiving the same funding. Meanwhile, there still is need for funding agencies to clarify and standardize terms such as "non-profit organizations" and "for-profit research," as more universities are pursuing for-profit or commercial opportunities.

  4. Characterization of RD-114 Virus Isolated from a Commercial Canine Vaccine Manufactured Using CRFK Cells

    Science.gov (United States)

    Yoshikawa, Rokusuke; Sato, Eiji; Igarashi, Tatsuhiko; Miyazawa, Takayuki

    2010-01-01

    Recently, we found that several commercial pet vaccines were contaminated with an infectious endogenous retrovirus, RD-114-related virus. Here, we determined the entire nucleotide sequences of RD-114-related viruses isolated from CRFK cells and a vaccine manufactured using CRFK cells. These RD-114-related viruses were nearly identical to the authentic RD-114 virus. PMID:20631117

  5. TECHNOLOGY ROADMAPPING FOR IAEA SEALS.

    Energy Technology Data Exchange (ETDEWEB)

    HOFFHEINS,B.; ANNESE,C.; GOODMAN,M.; OCONNOR,W.; GUSHUE,S.; PEPPER,S.

    2003-07-13

    In the fall of 2002, the U.S. Support Program (USSP) initiated an effort to define a strategy or ''roadmap'' for future seals technologies and to develop a generalized process for planning safeguards equipment development, which includes seals and other safeguards equipment. The underlying objectives of the USSP include becoming more proactive than reactive in addressing safeguards equipment needs, helping the IAEA to maintain an inventory of cost-effective, reliable, and effective safeguards equipment, establishing a long-term planning horizon, and securing IAEA ownership in the process of effective requirements definition and timely transitioning of new or improved systems for IAEA use. At an initial workshop, seals, their functions, performance issues, and future embodiments were discussed in the following order: adhesive seals, metal seals, passive and active loop seals, ultrasonic seals, tamper indicating enclosures (including sample containers, equipment enclosures, and conduits). Suggested improvements to these technologies focused largely on a few themes: (1) The seals must be applied quickly, easily, and correctly; (2) Seals and their associated equipment should not unduly add bulk or weight to the inspectors load; (3) Rapid, in-situ verifiability of seals is desirable; and (4) Seal systems for high risk or high value applications should have two-way, remote communications. Based upon these observations and other insights, the participants constructed a skeletal approach for seals technology planning. The process begins with a top-level review of the fundamental safeguards requirements and extraction of required system features, which is followed by analysis of suitable technologies and identification of technology gaps, and finally by development of a planning schedule for system improvements and new technology integration. Development of a comprehensive procedure will require the partnership and participation of the IAEA. The

  6. Next-generation batteries and fuel cells for commercial, military, and space applications

    CERN Document Server

    Jha, A R

    2012-01-01

    Distilling complex theoretical physical concepts into an understandable technical framework, Next-Generation Batteries and Fuel Cells for Commercial, Military, and Space Applications describes primary and secondary (rechargeable) batteries for various commercial, military, spacecraft, and satellite applications for covert communications, surveillance, and reconnaissance missions. It emphasizes the cost, reliability, longevity, and safety of the next generation of high-capacity batteries for applications where high energy density, minimum weight and size, and reliability in harsh conditions are

  7. VistA 4 Product Roadmap

    Data.gov (United States)

    Department of Veterans Affairs — The VistA 4 Product Roadmap outlines how the Department of Veterans Affairs (VA), under the direction of the VistA Evolution Program, will build upon the previous...

  8. Roadmap-Based Level Clearing of Buildings

    KAUST Repository

    Rodriguez, Samuel

    2011-01-01

    In this paper we describe a roadmap-based approach for a multi-agent search strategy to clear a building or multi-story environment. This approach utilizes an encoding of the environment in the form of a graph (roadmap) that is used to encode feasible paths through the environment. The roadmap is partitioned into regions, e.g., one per level, and we design region-based search strategies to cover and clear the environment. We can provide certain guarantees within this roadmap-based framework on coverage and the number of agents needed. Our approach can handle complex and realistic environments where many approaches are restricted to simple 2D environments. © 2011 Springer-Verlag.

  9. Commercialization basics for the photonics industry

    CERN Document Server

    Krohn, David A

    2013-01-01

    Most entrepreneurs have expertise in one or more of the critical areas of commercialization, but may lack key elements necessary for success. Commercialization Basics for the Photonics Industry serves as a roadmap for the commercialization process, helping identify and address roadblocks on the path to commercialization. Evaluation techniques will help determine the strength of a business opportunity and guide its development toward the best chance of success.

  10. Planetary Data System (PDS) Strategic Roadmap

    Science.gov (United States)

    Law, Emily; McNutt, Ralph; Crichton, Daniel J.; Morgan, Tom

    2016-07-01

    The Planetary Data System (PDS) archives and distributes scientific data from NASA planetary missions, astronomical observations, and laboratory measurements. NASA's Science Mission Directorate (SMD) sponsors the PDS. Its purpose is to ensure the long-term usability of NASA data and to stimulate advanced research. The Planetary Science Division (PSD) within the SMD at NASA Headquarters has directed the PDS to set up a Roadmap team to formulate a PDS Roadmap for the period 2017-2026. The purpose of this activity is to provide a forecast of both the rapidly changing Information Technology (IT) environment and the changing expectations of the planetary science communities with respect to Planetary Data archives including, specifically, increasing assessability to all planetary data. The Roadmap team will also identify potential actions that could increase interoperability with other archive and curation elements within NASA and with the archives of other National Space Agencies. The Roadmap team will assess the current state of the PDS and report their findings to the PSD Director by April 15, 2017. This presentation will give an update of this roadmap activity and serve as an opportunity to engage the planetary community at large to provide input to the Roadmap.

  11. BARRIERS TO COMMERCIALIZATION OF PASSIVE DIRECT METHANOL FUEL CELLS: A REVEIW

    Directory of Open Access Journals (Sweden)

    N. K. SHRIVASTAVA

    2011-07-01

    Full Text Available Fuel cells are electro-chemical reactors which realize the direct conversion of the chemical energy of reactants to electrical energy, with high efficiency and high environmental compatibility. This article is concerned with one of the most advance fuel cells- direct methanol fuel cells (DMFCs. We present a comprehensive review on the commercialization barriers of passive DMFCs. The paper also summarizes past research efforts and possible future directions towards these problems.

  12. Recent advances towards development and commercialization of plant cell culture processes for the synthesis of biomolecules.

    Science.gov (United States)

    Wilson, Sarah A; Roberts, Susan C

    2012-04-01

    Plant cell culture systems were initially explored for use in commercial synthesis of several high-value secondary metabolites, allowing for sustainable production that was not limited by the low yields associated with natural harvest or the high cost associated with complex chemical synthesis. Although there have been some commercial successes, most notably paclitaxel production from Taxus sp., process limitations exist with regards to low product yields and inherent production variability. A variety of strategies are being developed to overcome these limitations including elicitation, in situ product removal and metabolic engineering with single genes and transcription factors. Recently, the plant cell culture production platform has been extended to pharmaceutically active heterologous proteins. Plant systems are beneficial because they are able to produce complex proteins that are properly glycosylated, folded and assembled without the risk of contamination by toxins that are associated with mammalian or microbial production systems. Additionally, plant cell culture isolates transgenic material from the environment, allows for more controllable conditions over field-grown crops and promotes secretion of proteins to the medium, reducing downstream purification costs. Despite these benefits, the increase in cost of heterologous protein synthesis in plant cell culture as opposed to field-grown crops is significant and therefore processes must be optimized with regard to maximizing secretion and enhancing protein stability in the cell culture media. This review discusses recent advancements in plant cell culture processing technology, focusing on progress towards overcoming the problems associated with commercialization of these production systems and highlighting recent commercial successes.

  13. Cross-functional shifts in roadmapping: Sequence analysis of roadmapping practices at a large corporation

    NARCIS (Netherlands)

    Simonse, W.L.; Perks, H.

    2014-01-01

    This study unravels the nature of inter-functional integration in roadmapping. Roadmapping is indicated as an important innovation phenomenon and is practiced by multiple large organizations. Functional integration is widely acknowledged to play a significant role in enhancing new product success. R

  14. Roadmaps—A new tool for commercial space processing

    Science.gov (United States)

    Whitten, Raymond P.; Crawford, James L.

    1996-03-01

    This paper presents a new management and planning tool ``roadmaps'' for the commercial development and use of space. It is focused around the disciplines of biotechnology and material science. Roadmaps have evolved from changes in U.S. space policy and NASA strategic plans. The evolution of the Roadmaps concept is tied to five observations: 1) Space Processing Division projects are not subject to standard ``peer'' reviews; 2) government funding requires early commercial investments in space; 3) marketable products are essential to the program mission; 4) funding of new science or technology is incidental to new product development; and 5) the use of roadmaps forces early planning to the market. The result is a course chartered for the future development of products in biotechnology and materials using space based infrastructure and technology development. These tools chart a course for commercial space processing; where the project completion is the development of new products in biotechnology and materials using space based technology.

  15. Commercial-scale process design for thin-film solar cells

    Science.gov (United States)

    Russell, T. W. F.; Baron, B. N.; Rocheleau, R. E.

    Process and manufacturing costs for commercial-scale production of thin-film solar cells are examined from the viewpoint of the chemical process industry, with emphasis on CdS/Cu2S cells. The cells comprise opaque contact, collector/converter, absorber/generator, transparent contact, and encapsulation/antireflective coating layers. Each layer is deposited as a separate unit operation, through either continuous or batch processing methods. The scale-up of laboratory-verified cell manufacturing steps to commercial processing is detailed from the choice of a Zn-plated copper foil substrate to the bonding of a 1/16 in. tempered glass protective layer with polyvinyl butyral. The total product cost is calculated as a sum of raw materials, utilities, labor, and capital investment costs, using a cost/W for a 1 GW plant. Continuous processing results in a $0.50/W cell with raw materials accounting for 38% of the total product cost.

  16. A Roadmap to Interstellar Flight

    CERN Document Server

    Lubin, Philip

    2016-01-01

    In the nearly 60 years of spaceflight we have accomplished wonderful feats of exploration that have shown the incredible spirit of the human drive to explore and understand our universe. Yet in those 60 years we have barely left our solar system with the Voyager 1 spacecraft launched in 1977 finally leaving the solar system after 37 years of flight at a speed of 17 km/s or less than 0.006% the speed of light. As remarkable as this is we will never reach even the nearest stars with our current propulsion technology in even 10 millennium. We have to radically rethink our strategy or give up our dreams of reaching the stars, or wait for technology that does not currently exist. While we all dream of human spaceflight to the stars in a way romanticized in books and movies, it is not within our power to do so, nor it is clear that this is the path we should choose. We posit a technological path forward, that while not simple, it is within our technological reach. We propose a roadmap to a program that will lead to...

  17. Technology Roadmaps: Concentrating Solar Power

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-07-01

    The emerging technology known as concentrating solar power, or CSP, holds much promise for countries with plenty of sunshine and clear skies. Its electrical output matches well the shifting daily demand for electricity in places where airconditioning systems are spreading. When backed up by thermal storage facilities and combustible fuel, it offers utilities electricity that can be dispatched when required, enabling it to be used for base, shoulder and peak loads. Within about one to two decades, it will be able to compete with coal plants that emit high levels of CO2. The sunniest regions, such as North Africa, may be able to export surplus solar electricity to neighbouring regions, such as Europe, where demand for electricity from renewable sources is strong. In the medium-to-longer term, concentrating solar facilities can also produce hydrogen, which can be blended with natural gas, and provide low-carbon liquid fuels for transport and other end-use sectors. For CSP to claim its share of the coming energy revolution, concerted action is required over the next ten years by scientists, industry, governments, financing institutions and the public. This roadmap is intended to help drive these indispensable developments.

  18. Bioculture System: Expanding ISS Space Bioscience Capabilities for Fundamental Stem Cell Research and Commercial Applications

    Science.gov (United States)

    Blaber, Elizabeth; Dvorochkin, Natalya; Almeida, Eduardo; Fitzpatrick, Garret; Ellingson, Lance; Mitchell, Sarah; Yang, Anthony; Kosnik, Cristine; Rayl, Nicole; Cannon, Tom; Austin, Edward; Sato, Kevin

    With the recent call by the 2011 Decadal Report and the 2010 Space Biosciences Roadmap for the International Space Station (ISS) to be used as a National Laboratory for scientific research, there is now a need for new laboratory instruments on ISS to enable such research to occur. The Bioculture System supports the extended culturing of multiple cell types and microbiological specimens. It consists of a docking station that carries ten independent incubation units or ‘Cassettes’. Each Cassette contains a cooling chamber (5(°) C) for temperature sensitive solutions and samples, or long duration fluids and sample storage, as well as an incubation chamber (ambient up to 42(°) C). Each Cassette houses an independent fluidics system comprised of a biochamber, medical-grade fluid tubing, medium warming module, oxygenation module, fluid pump, and sixteen solenoid valves for automated biochamber injections of sampling. The Bioculture System provides the user with the ability to select the incubation temperature, fluid flow rate and automated biochamber sampling or injection events for each separate Cassette. Furthermore, the ISS crew can access the biochamber, media bag, and accessory bags on-orbit using the Microgravity Science Glovebox. The Bioculture System also permits initiation of cultures, subculturing, injection of compounds, and removal of samples for on-orbit processing using ISS facilities. The Bioculture System therefore provides a unique opportunity for the study of stem cells and other cell types in space. The first validation flight of the Bioculture System will be conducted on SpaceX5, consisting of 8 Cassettes and lasting for 30-37 days. During this flight we plan to culture two different mammalian cell types in bioreactors: a mouse osteocytic-like cell line, and human induced pluripotent stem cell (iPS)-derived cardiomyocytes. Specifically, the osteocytic line will enable the study of a type of cell that has been flown on the Bioculture System

  19. High Efficiency Spectrum Splitting Prototype Submodule Using Commercial CPV Cells (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Keevers, M.; Lau, J.; Green, M.; Thomas, I.; Lasich, J.; King, R.; Emery, K.

    2014-11-01

    This presentation summarizes progress on the design, fabrication and testing of a proof-of-concept, prototype spectrum splitting CPV submodule using commercial CPV cells, aimed at demonstrating an independently confirmed efficiency above 40% at STC (1000 W/m2, AM1.5D ASTM G173-03, 25 degrees C).

  20. Overview of commercialization of stationary fuel cell power plants in the United States

    Energy Technology Data Exchange (ETDEWEB)

    Hooie, D.T.; Williams, M.C.

    1995-07-01

    In this paper, DOE`s efforts to assist private sector organizations to develop and commercialize stationary fuel cell power plants in the United States are discussed. The paper also provides a snapshot of the status of stationary power fuel cell development occurring in the US, addressing all fuel cell types. This paper discusses general characteristics, system configurations, and status of test units and demonstration projects. The US DOE, Morgantown Energy Technology Center is the lead center for implementing DOE`s program for fuel cells for stationary power.

  1. Overview of cell-free protein synthesis: historic landmarks, commercial systems, and expanding applications.

    Science.gov (United States)

    Chong, Shaorong

    2014-10-01

    During the early days of molecular biology, cell-free protein synthesis played an essential role in deciphering the genetic code and contributed to our understanding of translation of protein from messenger RNA. Owing to several decades of major and incremental improvements, modern cell-free systems have achieved higher protein synthesis yields at lower production costs. Commercial cell-free systems are now available from a variety of material sources, ranging from "traditional" E. coli, rabbit reticulocyte lysate, and wheat germ extracts, to recent insect and human cell extracts, to defined systems reconstituted from purified recombinant components. Although each cell-free system has certain advantages and disadvantages, the diversity of the cell-free systems allows in vitro synthesis of a wide range of proteins for a variety of downstream applications. In the post-genomic era, cell-free protein synthesis has rapidly become the preferred approach for high-throughput functional and structural studies of proteins and a versatile tool for in vitro protein evolution and synthetic biology. This unit provides a brief history of cell-free protein synthesis and describes key advances in modern cell-free systems, practical differences between widely used commercial cell-free systems, and applications of this important technology.

  2. Creating small roadmaps for solving motion planning problems

    NARCIS (Netherlands)

    Geraerts, R.J.; Overmars, M.H.

    2005-01-01

    In robot motion planning, many algorithms have been proposed that create a roadmap from which a path for a moving object can be extracted. These algorithms generally do not give guarantees on the quality of the roadmap, i.e. they do not promise that a path will always be found in the roadmap if one

  3. Proposed roadmap for overcoming legal and financial obstacles to carbon capture and sequestration

    Energy Technology Data Exchange (ETDEWEB)

    Jacobs, Wendy (Harvard Environmental Law and Policy, Cambridge, MA (US)); Chohen, Leah; Kostakidis-Lianos, Leah; Rundell, Sara (Harvard Law School, Cambridge, MA (US))

    2009-03-01

    Many existing proposals either lack sufficient concreteness to make carbon capture and geological sequestration (CCGS) operational or fail to focus on a comprehensive, long term framework for its regulation, thus failing to account adequately for the urgency of the issue, the need to develop immediate experience with large scale demonstration projects, or the financial and other incentives required to launch early demonstration projects. We aim to help fill this void by proposing a roadmap to commercial deployment of CCGS in the United States.This roadmap focuses on the legal and financial incentives necessary for rapid demonstration of geological sequestration in the absence of national restrictions on CO2 emissions. It weaves together existing federal programs and financing opportunities into a set of recommendations for achieving commercial viability of geological sequestration.

  4. Technology Roadmap: Lab-on-a-Chip

    Directory of Open Access Journals (Sweden)

    Pattharaporn Suntharasaj

    2010-04-01

    Full Text Available With the integration of microfluidic and MEMS technologies, biochips such as the lab-on-a-chip (LOC devices are at the brink of revolutionizing the medical disease diagnostics industries. Remarkable advancements in the biochips industry are making products resembling Star Trek.s "tricorder" and handheld medical scanners a reality. Soon, doctors can screen for cancer at the molecular level without costly and cumbersome equipments, and discuss treatment plans based on immediate lab results. This paper develops a roadmap for a hypothetical company (XI which is seeking to be successful in this market. The roadmapping process starts with gathering data through literature research and expert opinions, and progress through defining the market/product/technology layers, linking and integrating these layers, and finally creating a labon-a-chip for disease diagnostics technology roadmap.

  5. Technology Roadmaps: Bioenergy for Heat and Power

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-07-01

    The Technology Roadmap Bioenergy for Heat and Power highlights the importance of bioenergy in providing heat in the buildings sector and in industry, and shows what contribution it could make to meeting steadlily growing world electricity demand. The critical role of sustainability as well as the importance of international trade in meeting the projected demand for bioenergy, are highlighted in the roadmap, as well as the need for large-scale biomass plants in providing The roadmap identifies key actions by different stakeholders in the bioenergy sector, and sets out milestones for technology development in order to achieve a doubling of global bioenergy supply by 2050. It addresses the need for further R&D efforts, highlights measures to ensure sustainability of biomass production, and underlines the need for international collaboration to enhance the production and use of sustainable, modern bioenergy in different world regions.

  6. Technology Roadmaps: Bioenergy for Heat and Power

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-08-01

    The Technology Roadmap Bioenergy for Heat and Power highlights the importance of bioenergy in providing heat in the buildings sector and in industry, and shows what contribution it could make to meeting steadlily growing world electricity demand. The critical role of sustainability as well as the importance of international trade in meeting the projected demand for bioenergy, are highlighted in the roadmap, as well as the need for large-scale biomass plants in providing The roadmap identifies key actions by different stakeholders in the bioenergy sector, and sets out milestones for technology development in order to achieve a doubling of global bioenergy supply by 2050. It addresses the need for further R&D efforts, highlights measures to ensure sustainability of biomass production, and underlines the need for international collaboration to enhance the production and use of sustainable, modern bioenergy in different world regions.

  7. Fuel cells are a commercially viable alternative for the production of "clean" energy.

    Science.gov (United States)

    Niakolas, Dimitris K; Daletou, Maria; Neophytides, Stylianos G; Vayenas, Constantinos G

    2016-01-01

    Fuel cells present a highly efficient and environmentally friendly alternative technology for decentralized energy production. The scope of the present study is to provide an overview of the technological and commercialization readiness level of fuel cells. Specifically, there is a brief description of their general advantages and weaknesses in correlation with various technological actions and political strategies, which are adopted towards their proper positioning in the global market. Some of the most important key performance indicators are also discussed, alongside with a few examples of broad commercialization. It is concluded that the increasing number of companies which utilize and invest on this technology, in combination with the supply chain improvements and the concomitant technological maturity and recognition, reinforce the fuel cell industry so as to become well-aligned for global success.

  8. Towards a commercial process for the manufacture of genetically modified T cells for therapy.

    Science.gov (United States)

    Kaiser, A D; Assenmacher, M; Schröder, B; Meyer, M; Orentas, R; Bethke, U; Dropulic, B

    2015-03-01

    The recent successes of adoptive T-cell immunotherapy for the treatment of hematologic malignancies have highlighted the need for manufacturing processes that are robust and scalable for product commercialization. Here we review some of the more outstanding issues surrounding commercial scale manufacturing of personalized-adoptive T-cell medicinal products. These include closed system operations, improving process robustness and simplifying work flows, reducing labor intensity by implementing process automation, scalability and cost, as well as appropriate testing and tracking of products, all while maintaining strict adherence to Current Good Manufacturing Practices and regulatory guidelines. A decentralized manufacturing model is proposed, where in the future patients' cells could be processed at the point-of-care in the hospital.

  9. Managing probe applications effectively? The process of pre-commercial fuel cell applications

    Energy Technology Data Exchange (ETDEWEB)

    Hellman, H.L. [Delft Univ. of Technology, Delft (Netherlands)

    2007-07-01

    There has been a high degree of uncertainty regarding market adoption of proton exchange membrane (PEM) fuel cell technologies, making it challenging for fuel cell firms to determine which markets to pursue at which point in time. Probes, such as prototypes, demonstrations and field trials, are market experiments conducted by fuel cell firms and industry that are central to the commercialization of fuel cell technology. However, demonstration projects are extremely resource and time intensive, and outcomes are uncertain. This paper reviewed innovation management literature on the characteristics of the technology application process. Case study research of four fuel cell firms were discussed in terms of probe objectives and outcomes. An analysis of probe application patterns over time was also presented. Several fuel cell projects were also analyzed in terms of motivations and lessons learned. The paper focused on young independent fuel cell developers that had limited resources to allocate and waste resources on ineffective probe applications. The findings complement prior research that have found probe applications a valuable tool for learning, stimulating market demand and network formation. The paper made several recommendations regarding the main objectives of the fuel cell project, to set realistic goals and align expectations between consortia members. In addition, it was found that a short term demonstration project may appear to be an attractive application, but a project with a longer term vision and a commercial value proposition was more likely to attract stakeholders. 16 refs., 3 figs.

  10. Hydrogen Storage Technical Team Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    None

    2013-06-01

    The mission of the Hydrogen Storage Technical Team is to accelerate research and innovation that will lead to commercially viable hydrogen-storage technologies that meet the U.S. DRIVE Partnership goals.

  11. Proton exchange membrane fuel cells for electrical power generation on-board commercial airplanes.

    Energy Technology Data Exchange (ETDEWEB)

    Curgus, Dita Brigitte; Munoz-Ramos, Karina (Sandia National Laboratories, Albuquerque, NM); Pratt, Joseph William; Akhil, Abbas Ali (Sandia National Laboratories, Albuquerque, NM); Klebanoff, Leonard E.; Schenkman, Benjamin L. (Sandia National Laboratories, Albuquerque, NM)

    2011-05-01

    Deployed on a commercial airplane, proton exchange membrane fuel cells may offer emissions reductions, thermal efficiency gains, and enable locating the power near the point of use. This work seeks to understand whether on-board fuel cell systems are technically feasible, and, if so, if they offer a performance advantage for the airplane as a whole. Through hardware analysis and thermodynamic and electrical simulation, we found that while adding a fuel cell system using today's technology for the PEM fuel cell and hydrogen storage is technically feasible, it will not likely give the airplane a performance benefit. However, when we re-did the analysis using DOE-target technology for the PEM fuel cell and hydrogen storage, we found that the fuel cell system would provide a performance benefit to the airplane (i.e., it can save the airplane some fuel), depending on the way it is configured.

  12. Proton Exchange Membrane Fuel Cells for Electrical Power Generation On-Board Commercial Airplanes

    Energy Technology Data Exchange (ETDEWEB)

    Pratt, Joesph W. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Klebanoff, Leonard E. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Munoz-Ramos, Karina [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Akhil, Abbas A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Curgus, Dita B. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Schenkman, Benjamin L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2011-05-01

    Deployed on a commercial airplane, proton exchange membrane fuel cells may offer emissions reductions, thermal efficiency gains, and enable locating the power near the point of use. This work seeks to understand whether on-board fuel cell systems are technically feasible, and, if so, if they offer a performance advantage for the airplane as a whole. Through hardware analysis and thermodynamic and electrical simulation, we found that while adding a fuel cell system using today’s technology for the PEM fuel cell and hydrogen storage is technically feasible, it will not likely give the airplane a performance benefit. However, when we re-did the analysis using DOE-target technology for the PEM fuel cell and hydrogen storage, we found that the fuel cell system would provide a performance benefit to the airplane (i.e., it can save the airplane some fuel), depending on the way it is configured.

  13. Pathways to Commercial Success: Technologies and Products Supported by the Fuel Cell Technologies Program

    Energy Technology Data Exchange (ETDEWEB)

    Weakley, Steven A.; Brown, Scott A.

    2011-09-29

    The purpose of the project described in this report is to identify and document the commercial and emerging (projected to be commercialized within the next 3 years) hydrogen and fuel cell technologies and products that resulted from Department of Energy support through the Fuel Cell Technologies (FCT) Program in the Office of Energy Efficiency and Renewable Energy (EERE). To do this, Pacific Northwest National Laboratory (PNNL) undertook two efforts simultaneously to accomplish this project. The first effort was a patent search and analysis to identify hydrogen- and fuel-cell-related patents that are associated with FCT-funded projects (or projects conducted by DOE-EERE predecessor programs) and to ascertain the patents current status, as well as any commercial products that may have used the technology documented in the patent. The second effort was a series of interviews with current and past FCT personnel, a review of relevant program annual reports, and an examination of hydrogen- and fuel-cell-related grants made under the Small Business Innovation Research and Small Business Technology Transfer Programs, and within the FCT portfolio.

  14. Pathways to Commercial Success: Technologies and Products Supported by the Fuel Cell Technologies Program

    Energy Technology Data Exchange (ETDEWEB)

    Weakley, Steven A.

    2012-09-28

    The purpose of the project described in this report is to identify and document the commercial and emerging (projected to be commercialized within the next 3 years) hydrogen and fuel cell technologies and products that resulted from Department of Energy support through the Fuel Cell Technologies (FCT) Program in the Office of Energy Efficiency and Renewable Energy (EERE). Pacific Northwest National Laboratory (PNNL) undertook two efforts simultaneously to accomplish this project. The first effort was a patent search and analysis to identify patents related to hydrogen and fuel cells that are associated with FCT-funded projects (or projects conducted by DOE-EERE predecessor programs) and to ascertain the patents’ current status, as well as any commercial products that may have used the technology documented in the patent. The second effort was a series of interviews with current and past FCT personnel, a review of relevant program annual reports, and an examination of grants made under the Small Business Innovation Research and Small Business Technology Transfer Programs that are related to hydrogen and fuel cells.

  15. Introduction to technology roadmapping: The semiconductor industry association`s technology roadmapping process

    Energy Technology Data Exchange (ETDEWEB)

    Garcia, M.L.

    1997-04-01

    A technology roadmap is the result of a strategic technology planning process that cooperatively identifies (1) a particular industry`s common product and process performance targets, (2) the technology alternatives and milestones for meeting these targets, and (3) a common technology path for research and development activities. The author describes a successful major roadmapping experience - the Semiconductor Industry Association`s Technology Roadmapping Process, which culminated in a workshop held in 1992. The report explains the committee structure and processes that were used both before and after the workshop and presents principles and practices that can aid future technology roadmappers. Appendix 1 summarizes the process from a committee-structure viewpoint. Appendix 2 summarizes the process from a functional view-point. Appendix 3 answers some frequently asked questions about technology roadmapping.

  16. Strategic Green Energy Roadmap 2011 for South Korea; Koreaanse strategische groene energie roadmap 2011

    Energy Technology Data Exchange (ETDEWEB)

    Wijlhuizen, P.

    2011-08-23

    The South Korean energy system depends for 97% on import. The remaining three percent of the energy need is covered by hydropower, solar panels and wind turbines. Korea is looking for alternatives, both for import and for fossil fuels. In 2008, Korea developed its 'Low carbon, green growth' policy, followed by the first 'Strategic green energy roadmap' one year later. Mid-2011 the Ministry of Knowledge Economy published an updated roadmap. [Dutch] Zuid-Korea is voor de energievoorziening voor 97% afhankelijk van import. De resterende drie procent van de energiebehoefte wordt door waterkracht, zonnepanelen en windmolens opgewekt. Korea zoekt naar alternatieven voor zowel import als voor fossiele brandstoffen. In 2008 kwam Korea met het 'Low carbon, green growth' beleid en een jaar later kwam de eerste 'Strategische groene energie roadmap' uit. Midden 2011 kwam het Ministry of Knowledge Economy met een ge-updatete roadmap.

  17. The 2015 super-resolution microscopy roadmap

    Science.gov (United States)

    Hell, Stefan W.; Sahl, Steffen J.; Bates, Mark; Zhuang, Xiaowei; Heintzmann, Rainer; Booth, Martin J.; Bewersdorf, Joerg; Shtengel, Gleb; Hess, Harald; Tinnefeld, Philip; Honigmann, Alf; Jakobs, Stefan; Testa, Ilaria; Cognet, Laurent; Lounis, Brahim; Ewers, Helge; Davis, Simon J.; Eggeling, Christian; Klenerman, David; Willig, Katrin I.; Vicidomini, Giuseppe; Castello, Marco; Diaspro, Alberto; Cordes, Thorben

    2015-11-01

    Far-field optical microscopy using focused light is an important tool in a number of scientific disciplines including chemical, (bio)physical and biomedical research, particularly with respect to the study of living cells and organisms. Unfortunately, the applicability of the optical microscope is limited, since the diffraction of light imposes limitations on the spatial resolution of the image. Consequently the details of, for example, cellular protein distributions, can be visualized only to a certain extent. Fortunately, recent years have witnessed the development of ‘super-resolution’ far-field optical microscopy (nanoscopy) techniques such as stimulated emission depletion (STED), ground state depletion (GSD), reversible saturated optical (fluorescence) transitions (RESOLFT), photoactivation localization microscopy (PALM), stochastic optical reconstruction microscopy (STORM), structured illumination microscopy (SIM) or saturated structured illumination microscopy (SSIM), all in one way or another addressing the problem of the limited spatial resolution of far-field optical microscopy. While SIM achieves a two-fold improvement in spatial resolution compared to conventional optical microscopy, STED, RESOLFT, PALM/STORM, or SSIM have all gone beyond, pushing the limits of optical image resolution to the nanometer scale. Consequently, all super-resolution techniques open new avenues of biomedical research. Because the field is so young, the potential capabilities of different super-resolution microscopy approaches have yet to be fully explored, and uncertainties remain when considering the best choice of methodology. Thus, even for experts, the road to the future is sometimes shrouded in mist. The super-resolution optical microscopy roadmap of Journal of Physics D: Applied Physics addresses this need for clarity. It provides guidance to the outstanding questions through a collection of short review articles from experts in the field, giving a thorough

  18. Failure statistics for commercial lithium ion batteries: A study of 24 pouch cells

    Science.gov (United States)

    Harris, Stephen J.; Harris, David J.; Li, Chen

    2017-02-01

    There are relatively few publications that assess capacity decline in enough commercial cells to quantify cell-to-cell variation, but those that do show a surprisingly wide variability. Capacity curves cross each other often, a challenge for efforts to measure the state of health and predict the remaining useful life (RUL) of individual cells. We analyze capacity fade statistics for 24 commercial pouch cells, providing an estimate for the time to 5% failure. Our data indicate that RUL predictions based on remaining capacity or internal resistance are accurate only once the cells have already sorted themselves into ;better; and ;worse; ones. Analysis of our failure data, using maximum likelihood techniques, provide uniformly good fits for a variety of definitions of failure with normal and with 2- and 3-parameter Weibull probability density functions, but we argue against using a 3-parameter Weibull function for our data. pdf fitting parameters appear to converge after about 15 failures, although business objectives should ultimately determine whether data from a given number of batteries provides sufficient confidence to end lifecycle testing. Increased efforts to make batteries with more consistent lifetimes should lead to improvements in battery cost and safety.

  19. Roadmap for In-Space Propulsion Technology

    Science.gov (United States)

    Meyer, Michael; Johnson, Les; Palaszewski, Bryan; Coote, David; Goebel, Dan; White, Harold

    2012-01-01

    NASA has created a roadmap for the development of advanced in-space propulsion technologies for the NASA Office of the Chief Technologist (OCT). This roadmap was drafted by a team of subject matter experts from within the Agency and then independently evaluated, integrated and prioritized by a National Research Council (NRC) panel. The roadmap describes a portfolio of in-space propulsion technologies that could meet future space science and exploration needs, and shows their traceability to potential future missions. Mission applications range from small satellites and robotic deep space exploration to space stations and human missions to Mars. Development of technologies within the area of in-space propulsion will result in technical solutions with improvements in thrust, specific impulse (Isp), power, specific mass (or specific power), volume, system mass, system complexity, operational complexity, commonality with other spacecraft systems, manufacturability, durability, and of course, cost. These types of improvements will yield decreased transit times, increased payload mass, safer spacecraft, and decreased costs. In some instances, development of technologies within this area will result in mission-enabling breakthroughs that will revolutionize space exploration. There is no single propulsion technology that will benefit all missions or mission types. The requirements for in-space propulsion vary widely according to their intended application. This paper provides an updated summary of the In-Space Propulsion Systems technology area roadmap incorporating the recommendations of the NRC.

  20. Lunar Surface Systems Supportability Technology Development Roadmap

    Science.gov (United States)

    Oeftering, Richard C.; Struk, Peter M.; Green, Jennifer L.; Chau, Savio N.; Curell, Philip C.; Dempsey, Cathy A.; Patterson, Linda P.; Robbins, William; Steele, Michael A.; DAnnunzio, Anthony; Meseroll, Robert; Quiter, John; Shannon, Russell; Easton, John W.; Madaras, Eric I.; BrownTaminger, Karen M.; Tabera, John T.; Tellado, Joseph; Williams, Marth K.; Zeitlin, Nancy P.

    2011-01-01

    The Lunar Surface Systems Supportability Technology Development Roadmap is a guide for developing the technologies needed to enable the supportable, sustainable, and affordable exploration of the Moon and other destinations beyond Earth. Supportability is defined in terms of space maintenance, repair, and related logistics. This report considers the supportability lessons learned from NASA and the Department of Defense. Lunar Outpost supportability needs are summarized, and a supportability technology strategy is established to make the transition from high logistics dependence to logistics independence. This strategy will enable flight crews to act effectively to respond to problems and exploit opportunities in an environment of extreme resource scarcity and isolation. The supportability roadmap defines the general technology selection criteria. Technologies are organized into three categories: diagnostics, test, and verification; maintenance and repair; and scavenge and recycle. Furthermore, "embedded technologies" and "process technologies" are used to designate distinct technology types with different development cycles. The roadmap examines the current technology readiness level and lays out a four-phase incremental development schedule with selection decision gates. The supportability technology roadmap is intended to develop technologies with the widest possible capability and utility while minimizing the impact on crew time and training and remaining within the time and cost constraints of the program.

  1. EPA Nitrogen and Co-Pollutant Roadmap

    Science.gov (United States)

    Cross-media, integrated, multi-disciplinary approach to sustainably manage reactive nitrogen and co-pollutant loadings to air and water to reduce adverse impacts on the environment and human health. The goal of the Roadmap is to develop a common understanding of the Agency's rese...

  2. A Comparative Study of Probabilistic Roadmap Planners

    NARCIS (Netherlands)

    Geraerts, R.J.; Overmars, M.H.

    2004-01-01

    The probabilistic roadmap approach is one of the leading motion planning techniques. Over the past eight years the technique has been studied by many different researchers. This has led to a large number of variants of the approach, each with its own merits. It is difficult to compare the different

  3. SCENET roadmap for superconductor digital electronics

    NARCIS (Netherlands)

    Brake, ter H.J.M.; Buchholz, F.-Im.; Burnell, G.; Claeson, T.; Crete, D.; Febvre, P.; Gerritsma, G.J.; Hilgenkamp, H.; .........,; Rogalla, H.; .........,

    2006-01-01

    The roadmap gives an overview on status and future developments in Superconducting Digital Electronics (SDE). Key areas in SDE under focus are applications, circuit simulation and design, circuit fabrication, interfacing and testing, cooling and system aspects, and new devices and materials. Care wa

  4. Project materials [Commercial High Performance Buildings Project

    Energy Technology Data Exchange (ETDEWEB)

    None

    2001-01-01

    The Consortium for High Performance Buildings (ChiPB) is an outgrowth of DOE'S Commercial Whole Buildings Roadmapping initiatives. It is a team-driven public/private partnership that seeks to enable and demonstrate the benefit of buildings that are designed, built and operated to be energy efficient, environmentally sustainable, superior quality, and cost effective.

  5. On the performance limiting behavior of defect clusters in commercial silicon solar cells

    Energy Technology Data Exchange (ETDEWEB)

    Sopori, B.L.; Chen, W.; Jones, K. [National Renewable Energy Lab., Golden, CO (United States); Gee, J. [Sandia National Labs., Albuquerque, NM (United States)

    1998-09-01

    The authors report the observation of defect clusters in high-quality, commercial silicon solar cell substrates. The nature of the defect clusters, their mechanism of formation, and precipitation of metallic impurities at the defect clusters are discussed. This defect configuration influences the device performance in a unique way--by primarily degrading the voltage-related parameters. Network modeling is used to show that, in an N/P junction device, these regions act as shunts that dissipate power generated within the cell.

  6. Thermal and Cycle-Life Behavior of Commercial Li-ion and Li-Polymer Cells

    Science.gov (United States)

    Zimmerman, Albert H.; Quinzio, M. V.

    2001-01-01

    Accelerated and real-time LEO cycle-life test data will be presented for a range of commercial Li-ion and Li-polymer (gel type) cells indicating the ranges of performance that can be obtained, and the performance screening tests that must be done to assure long life. The data show large performance variability between cells, as well as a highly variable degradation signature during non-cycling periods within the life tests. High-resolution Dynamic Calorimetry data will be presented showing the complex series of reactions occurring within these Li cells as they are cycled. Data will also be presented for cells being tested using an Adaptive Charge Control Algorithm (ACCA) that continuously adapts itself to changes in cell performance, operation, or environment to both find and maintain the optimum recharge over life. The ACCA has been used to prevent all unneeded overcharge for Li cells, NiCd cells and NiH2 cells. While this is important for all these cell types, it is most critical for Li-ion cells, which are not designed with electrochemical tolerance for overcharge.

  7. Monoplane 3D Overlay Roadmap versus Conventional Biplane 2D Roadmap Technique for Neurointervenional Procedures

    Science.gov (United States)

    Jang, Dong-Kyu; Stidd, David A.; Schafer, Sebastian; Chen, Michael; Moftakhar, Roham

    2016-01-01

    Purpose We investigated whether a 3D overlay roadmap using monoplane fluoroscopy offers advantages over a conventional 2D roadmap using biplane fluoroscopy during endovascular aneurysm treatment. Materials and Methods A retrospective chart review was conducted for 131 consecutive cerebral aneurysm embolizations by three neurointerventionalists at a single institution. Allowing for a transition period, the periods from January 2012 to August 2012 (Time Period 1) and February 2013 to July 2013 (Time Period 2) were analyzed for radiation exposure, contrast administration, fluoroscopy time, procedure time, angiographic results, and perioperative complications. Two neurointerventionalists (Group 1) used a conventional 2D roadmap for both Time Periods, and one neurointerventionalist (Group 2) transitioned from a 2D roadmap during Time Period 1 to a 3D overlay roadmap during Time Period 2. Results During Time Period 2, Group 2 demonstrated reduced fluoroscopy time (p<0.001), procedure time (P=0.023), total radiation dose (p=0.001), and fluoroscopy dose (P=0.017) relative to Group 1. During Time Period 2, there was no difference of immediate angiographic results and procedure complications between the two groups. Through the transition from Time Period 1 to Time Period 2, Group 2 demonstrated decreased fluoroscopy time (p< 0.001), procedure time (p=0.022), and procedure complication rate (p=0.041) in Time Period 2 relative to Time Period 1. Conclusion The monoplane 3D overlay roadmap technique reduced fluoroscopy dose and fluoroscopy time during neurointervention of cerebral aneurysms with similar angiographic occlusions and complications rate relative to biplane 2D roadmap, which implies possible compensation of limitations of monoplane fluoroscopy by 3D overlay technique. PMID:27621947

  8. Built Environment Wind Turbine Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    Smith, J. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Forsyth, T. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Sinclair, K. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Oteri, F. [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2012-11-01

    The market currently encourages BWT deployment before the technology is ready for full-scale commercialization. To address this issue, industry stakeholders convened a Rooftop and Built-Environment Wind Turbine Workshop on August 11 - 12, 2010, at the National Wind Technology Center, located at the U.S. Department of Energy’s National Renewable Energy Laboratory in Boulder, Colorado. This report summarizes the workshop.

  9. Pathways to Commercial Success: Technologies and Products Supported by the Hydrogen, Fuel Cells and Infrastructure Technologies Program

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2009-08-01

    This report documents the results of an effort to identify and characterize commercial and near-commercial (emerging) technologies and products that benefited from the support of the Hydrogen, Fuel Cells and Infrastructure Technologies Program and its predecessor programs within DOE's Office of Energy Efficiency and Renewable Energy.

  10. Book of Knowledge (BOK) for NASA Electronic Packaging Roadmap

    Science.gov (United States)

    Ghaffarian, Reza

    2015-01-01

    The objective of this document is to update the NASA roadmap on packaging technologies (initially released in 2007) and to present the current trends toward further reducing size and increasing functionality. Due to the breadth of work being performed in the area of microelectronics packaging, this report presents only a number of key packaging technologies detailed in three industry roadmaps for conventional microelectronics and a more recently introduced roadmap for organic and printed electronics applications. The topics for each category were down-selected by reviewing the 2012 reports of the International Technology Roadmap for Semiconductor (ITRS), the 2013 roadmap reports of the International Electronics Manufacturing Initiative (iNEMI), the 2013 roadmap of association connecting electronics industry (IPC), the Organic Printed Electronics Association (OE-A). The report also summarizes the results of numerous articles and websites specifically discussing the trends in microelectronics packaging technologies.

  11. The European Hematology Association Roadmap for European Hematology Research

    DEFF Research Database (Denmark)

    Engert, Andreas; Balduini, Carlo; Brand, Anneke

    2016-01-01

    research. Initiated by the EHA, around 300 experts contributed to the consensus document, which will help European policy makers, research funders, research organizations, researchers, and patient groups make better informed decisions on hematology research. It also aims to raise public awareness...... diseases, anemias and related diseases, platelet disorders, blood coagulation and hemostatic disorders, transfusion medicine, infections in hematology, and hematopoietic stem cell transplantation. These sections span 60 smaller groups of diseases or disorders.The EHA Roadmap identifies priorities and needs...... across the field of hematology, including those to develop targeted therapies based on genomic profiling and chemical biology, to eradicate minimal residual malignant disease, and to develop cellular immunotherapies, combination treatments, gene therapies, hematopoietic stem cell treatments...

  12. Use of fuel cells in residences and commercial establishments; Uso de celulas combustiveis em residencias e estabelecimentos comerciais

    Energy Technology Data Exchange (ETDEWEB)

    Serra, Eduardo T. [Centro de Pesquisas de Energia Eletrica, Rio de Janeiro, RJ (Brazil)

    2003-05-01

    This paper analyses the present technological stage and the economical feasibility of the application of low power fuel cells for meeting of the residence and small commercial units electric power consumption needs.

  13. Technology Roadmaps: Solar Heating and Cooling

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-07-01

    The solar heating and cooling (SHC) roadmap outlines a pathway for solar energy to supply almost one sixth (18 EJ) of the world’s total energy use for both heating and cooling by 2050. This would save some 800 megatonnes of carbon dioxide (CO2) emissions per year; more than the total CO2 emissions in Germany in 2009. While solar heating and cooling today makes a modest contribution to world energy demand, the roadmap envisages that if concerted action is taken by governments and industry, solar energy could annually produce more than 16% of total final energy use for low temperature heat and nearly 17% for cooling. Given that global energy demand for heat represents almost half of the world’s final energy use – more than the combined global demand for electricity and transport – solar heat can make a significant contribution in both tackling climate change and strengthening energy security.

  14. Technology Roadmaps: Solar Heating and Cooling

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-09-06

    The solar heating and cooling (SHC) roadmap outlines a pathway for solar energy to supply almost one sixth (18 EJ) of the world's total energy use for both heating and cooling by 2050. This would save some 800 megatonnes of carbon dioxide (CO2) emissions per year; more than the total CO2 emissions in Germany in 2009. While solar heating and cooling today makes a modest contribution to world energy demand, the roadmap envisages that if concerted action is taken by governments and industry, solar energy could annually produce more than 16% of total final energy use for low temperature heat and nearly 17% for cooling. Given that global energy demand for heat represents almost half of the world's final energy use -- more than the combined global demand for electricity and transport -- solar heat can make a significant contribution in both tackling climate change and strengthening energy security.

  15. Status of commercial phosphoric acid fuel cell power plant system development

    Science.gov (United States)

    Warshay, M.

    1987-01-01

    A technology development and commercial feasibility evaluation is presented for phosphoric acid fuel cells (PAFCs) applicable to electric utility operations. The correction of identified design deficiencies in the control card and water treatment subsystems is projected to be able to substantially increase average powerplant availability from the 63 percent achieved in recent field tests of a PAFC system. Current development work is proceeding under NASA research contracts at the output levels of a multimegawatt facility for electric utility use, a multikilowatt on-site integrated energy generation facility, and advanced electrocatalysts applicable to PAFCs.

  16. Design Through Analysis (DTA) roadmap vision.

    Energy Technology Data Exchange (ETDEWEB)

    Blacker, Teddy Dean; Adams, Charles R.; Hoffman, Edward L.; White, David Roger; Sjaardema, Gregory D.

    2004-10-01

    The Design through Analysis Realization Team (DART) will provide analysts with a complete toolset that reduces the time to create, generate, analyze, and manage the data generated in a computational analysis. The toolset will be both easy to learn and easy to use. The DART Roadmap Vision provides for progressive improvements that will reduce the Design through Analysis (DTA) cycle time by 90-percent over a three-year period while improving both the quality and accountability of the analyses.

  17. Strategic Roadmap 2024: Powering the Energy Frontier

    Energy Technology Data Exchange (ETDEWEB)

    None

    2014-05-01

    Strategic Roadmap 2024 applies our historic mission to the dynamic and evolving industry environment that includes myriad new regulations, the growing presence of interruptible and intermittent generation resources and constraints on our hydro resources. It also ties together Western’s strategy, initiatives, capital budgets and annual targets to move the agency in one direction, continue to meet customer needs and provide the best value as an organization.

  18. MEGAHIT Roadmap: Applications for Nuclear Electric Propulsion

    OpenAIRE

    Jansen, Frank; Semenkin, Alexander; Bauer, Waldemar; WORMS, Jean-Claude; Detsis, Emmanouil; CLIQUET-MORENO, Elisa; Masson, Frederic; Ruault, Jean-Marc; Gaia, Enrico; Cristina, T.M.; Tinsley, Tim; Hodgson, Zara

    2014-01-01

    The paper introduces the three EC funded nuclear electric propulsion funded projects DiPoP, MEGAHIT and DEMOCRITOS. It describes in detail the European-Russian MEGAHIT project - the study outputs, the proposal for a key technology plan, a plan for a political and public supportable reference space mission. Moreover the content of the MEGAHIT global roadmap for international realization of the INPPS (International Nuclear Power and Propulsion System) is sketched.

  19. Electrical and Electronics Technical Team Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    None

    2013-06-01

    The Electrical and Electronics Technical Team’s (EETT's) mission is to enable cost-effective, smaller, lighter, and efficient power electronics and electric motors for electric traction drive systems (ETDSs) while maintaining performance of internal combustion engine (ICE)-based vehicles. The EETT also identifies technology gaps, establishes R&D targets, develops a roadmap to achieve technical targets and goals, and evaluates the R&D progress toward meeting the established R&D targets and goals.

  20. Codes and Standards Technical Team Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    None

    2013-06-01

    The Hydrogen Codes and Standards Tech Team (CSTT) mission is to enable and facilitate the appropriate research, development, & demonstration (RD&D) for the development of safe, performance-based defensible technical codes and standards that support the technology readiness and are appropriate for widespread consumer use of fuel cells and hydrogen-based technologies with commercialization by 2020. Therefore, it is important that the necessary codes and standards be in place no later than 2015.

  1. The EU fusion programme and roadmap

    Energy Technology Data Exchange (ETDEWEB)

    Pero, H., E-mail: Herve.Pero@ec.europa.eu [European Commission, DG-RTD, CDMA 05/146, B-1049 Brussels (Belgium); Paidassi, S. [European Commission, DG-RTD, CDMA 05/146, B-1049 Brussels (Belgium)

    2013-02-15

    Highlights: ► The EU fusion programme has to evolve from today's research to a strong goal-oriented programme driven by an ambitious roadmap. ► The programme shall focus on ITER and reactor-relevant technologies development. ► A new structure based on joint programming will be developed to implement the programme during Horizon 2020. -- Abstract: To meet ITER and fusion energy challenges, a gradual transition of the EU fusion programme priorities from today's fusion research to a strongly goal-oriented programme with clear milestones is required. This transition and the programme priorities should be driven by an ambitious, yet realistic roadmap to be agreed by EU fusion stakeholders. The programme must primarily focus on: ensuring the success of ITER; and research and development of reactor-relevant technologies. Industry must be involved early in the implementation and international collaboration should be conducted as part of a strategic approach. Joint programming should be a cornerstone of the EU fusion programme in Horizon 2020. Options for the new structure and current actions required to implement the roadmap during Horizon 2020 will be presented.

  2. Technology Roadmap: Wind Energy. 2013 edition

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-07-01

    The IEA Wind Power Technology Roadmap 2013 Edition recognises the very significant progress made since the first edition was published in 2009. The technology continues to improve rapidly, and costs of generation from land-based wind installations continue to fall. Wind power is now being deployed in countries with good resources without any dedicated financial incentives. The 2013 Edition targets an increased share (15% to 18%) of global electricity to be provided by wind power in 2050, compared to 12% in the original roadmap of 2009. However, increasing levels of low-cost wind still require predictable, supportive regulatory environments and appropriate market designs. The challenges of integrating higher levels of variable wind power into the grid need to be addressed. For offshore wind, much remains to be done to develop appropriate large-scale systems and to reduce costs. The 2013 Wind Power Roadmap also provides updated analysis on the barriers that exist for the technology and suggests ways to address them, including legal and regulatory recommendations.

  3. AstRoMap European Astrobiology Roadmap.

    Science.gov (United States)

    Horneck, Gerda; Walter, Nicolas; Westall, Frances; Grenfell, John Lee; Martin, William F; Gomez, Felipe; Leuko, Stefan; Lee, Natuschka; Onofri, Silvano; Tsiganis, Kleomenis; Saladino, Raffaele; Pilat-Lohinger, Elke; Palomba, Ernesto; Harrison, Jesse; Rull, Fernando; Muller, Christian; Strazzulla, Giovanni; Brucato, John R; Rettberg, Petra; Capria, Maria Teresa

    2016-03-01

    The European AstRoMap project (supported by the European Commission Seventh Framework Programme) surveyed the state of the art of astrobiology in Europe and beyond and produced the first European roadmap for astrobiology research. In the context of this roadmap, astrobiology is understood as the study of the origin, evolution, and distribution of life in the context of cosmic evolution; this includes habitability in the Solar System and beyond. The AstRoMap Roadmap identifies five research topics, specifies several key scientific objectives for each topic, and suggests ways to achieve all the objectives. The five AstRoMap Research Topics are • Research Topic 1: Origin and Evolution of Planetary Systems • Research Topic 2: Origins of Organic Compounds in Space • Research Topic 3: Rock-Water-Carbon Interactions, Organic Synthesis on Earth, and Steps to Life • Research Topic 4: Life and Habitability • Research Topic 5: Biosignatures as Facilitating Life Detection It is strongly recommended that steps be taken towards the definition and implementation of a European Astrobiology Platform (or Institute) to streamline and optimize the scientific return by using a coordinated infrastructure and funding system.

  4. RF MEMS: status of the industry and roadmaps

    Science.gov (United States)

    Bouchaud, Jeremie; Wicht, Henning

    2005-01-01

    Microsystems for Radio Frequency applications, known as RF MEMS, have entered the commercialization phase in 2003. Bulk Acoustic Wave filters are already produced in series and first commercial samples of switches are available. On the other hand, reliability and packaging problems are still a major hurdle especially for switches and tunable capacitors. Will RF MEMS hold their promise to be one of the future major businesses for MEMS? The presentation will give an overview on RF MEMS applications and market players. WTC will highlight technical challenges that still have to be solved to open mass markets such as mobile telephony and WLAN. WTC will also present applications of RF MEMS and opportunities in niche markets with high added value like military and space applications. WTC will provide a regional analysis and compare R&D focus and public funding situation in North America, Europe and Asia. Finally, WTC will present an updated product roadmap market forecast for RF MEMS devices for the 2004-2008 time period.

  5. Extensive EIS characterization of commercially available lithium polymer battery cell for performance modelling

    DEFF Research Database (Denmark)

    Stanciu, Tiberiu; Stroe, Daniel Loan; Teodorescu, Remus;

    2015-01-01

    or degradation of an electrochemical system. Used for Lithium-ion (Li-ion) batteries, this method allows for a fast and accurate assessment of the battery's impedance at any working point, without modifying the state of the battery. The influence of the operating conditions, state of charge (SOC) and temperature......Electrochemical Impedance Spectroscopy (EIS) has become a popular analytical technique for research and development of battery cells' chemistries, due to the established, high precision computer controlled equipment, that are capable of direct, on-line monitoring of performance parameters...... on the performance of a commercially available 53 Ah Lithium polymer battery cell, manufactured by Kokam Co. Ltd., is investigated in laboratory experiments, at its beginning of life, by means of EIS. A data fitting algorithm was used to obtain the parameter values for the proposed equivalent electrical circuit...

  6. Commercial materials as cathode for hydrogen production in microbial electrolysis cell.

    Science.gov (United States)

    Farhangi, Sara; Ebrahimi, Sirous; Niasar, Mojtaba Shariati

    2014-10-01

    The use of commercial electrodes as cathodes in a single-chamber microbial electrolysis cell has been investigated. The cell was operated in sequencing batch mode and the performance of the electrodes was compared with carbon cloth containing 0.5 mg Pt cm(-2). Overall H2 recovery [Formula: see text] was 66.7 ± 1.4, 58.7 ± 1.1 and 55.5 ± 1.5 % for Pt/CC, Ni and Ti mesh electrodes, respectively. Columbic efficiencies of the three cathodes were in the same range (74.8 ± 1.5, 77.6 ± 1.7 and 75.7 ± 1.2 % for Pt/CC, Ni and Ti mesh electrodes, respectively). A similar performance for the three cathodes under near-neutral pH and ambient temperature was obtained. The commercial electrodes are much cheaper than carbon cloth containing Pt. Low cost and good performance of these electrodes suggest they are suitable cathode materials for large scale application.

  7. Studies of the energy and power of current commercial prismatic and cylindrical Li-ion cells

    Science.gov (United States)

    Sit, Kevin; Li, P. K. C.; Ip, C. W.; Li, C. W.; Wan, Levin; Lam, Y. F.; Lai, P. Y.; Fan, Jiang; Magnuson, Doug

    We studied the specific energy, energy density, specific power, and power density of current commercial 18650 cylindrical and 103450 prismatic Li-ion cells. It was found that the specific energy, energy density, specific power, and power density have been increased dramatically since 1999. The highest specific energy obtained in this study is 193 Wh/kg, which is 90% more than that reported in 1999 and is only 5% lower than 200 Wh/kg, the long-term DOE goal [The International Energy Agency Implementing Agreement for Electric Vehicle Technologies and Programs, Annex V, Outlook Document, 1996-1997, p. 16.]. The cell energy density has also doubled since 1999 and is as much as about 70% more than 300 Wh/l, the long-term DOE goal. The cells studied here can deliver over 80% of their designed energy at the specific power 200 W/kg while the 18650 cell studied previously could only deliver 10% of their designed energy at the same specific power. Various kinds of the factors in the cell-specific energy and energy density were studied. It seems that the geometric difference can cause as much as a 9% difference in the specific energy and a 12% difference in the energy density between 18650 cylindrical and 103450 prismatic cells. Use of an aluminum can seems to lead to about a 16% improvement in the specific energy of 103450 cells compared with steel can. The decrease in the cell discharge voltage can cause as much as a 9% decrease in the cell energy at the 2 C rate while it has a relatively small effect on the cell energy or specific energy at the 0.2 C rate. Compared with what has been obtained at room temperature, there are 17-35% at -20 °C, 43-76% at -30 °C, and 78-100% decreases at -40 °C, respectively, in the cell discharge energy and specific energy depending on the cell manufacturer. The decrease in the cell average discharge voltage during the cycling test can contribute as much as a 6% decrease in the cell energy at the 1 C rate after 300 cycles, which is 21% of

  8. Hydrogen Delivery Technical Team Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    None

    2013-06-01

    The mission of the Hydrogen Delivery Technical Team (HDTT) is to enable the development of hydrogen delivery technologies, which will allow for fuel cell competitiveness with gasoline and hybrid technologies by achieving an as-produced, delivered, and dispensed hydrogen cost of $2-$4 per gallon of gasoline equivalent of hydrogen.

  9. Astaxanthin-Producing Green Microalga Haematococcus pluvialis: From Single Cell to High Value Commercial Products.

    Science.gov (United States)

    Shah, Md Mahfuzur R; Liang, Yuanmei; Cheng, Jay J; Daroch, Maurycy

    2016-01-01

    Many species of microalgae have been used as source of nutrient rich food, feed, and health promoting compounds. Among the commercially important microalgae, Haematococcus pluvialis is the richest source of natural astaxanthin which is considered as "super anti-oxidant." Natural astaxanthin produced by H. pluvialis has significantly greater antioxidant capacity than the synthetic one. Astaxanthin has important applications in the nutraceuticals, cosmetics, food, and aquaculture industries. It is now evident that, astaxanthin can significantly reduce free radicals and oxidative stress and help human body maintain a healthy state. With extraordinary potency and increase in demand, astaxanthin is one of the high-value microalgal products of the future.This comprehensive review summarizes the most important aspects of the biology, biochemical composition, biosynthesis, and astaxanthin accumulation in the cells of H. pluvialis and its wide range of applications for humans and animals. In this paper, important and recent developments ranging from cultivation, harvest and postharvest bio-processing technologies to metabolic control and genetic engineering are reviewed in detail, focusing on biomass and astaxanthin production from this biotechnologically important microalga. Simultaneously, critical bottlenecks and major challenges in commercial scale production; current and prospective global market of H. pluvialis derived astaxanthin are also presented in a critical manner. A new biorefinery concept for H. pluvialis has been also suggested to guide toward economically sustainable approach for microalgae cultivation and processing. This report could serve as a useful guide to present current status of knowledge in the field and highlight key areas for future development of H. pluvialis astaxanthin technology and its large scale commercial implementation.

  10. Astaxanthin-producing green microalga Haematococcus pluvialis: from single cell to high value commercial products

    Directory of Open Access Journals (Sweden)

    Md. Mahfuzur Rahman Shah

    2016-04-01

    Full Text Available Many species of microalgae have been used as source of nutrient rich food, feed and health promoting compounds. Among the commercially important microalgae, Haematococcus pluvialis is the richest source of natural astaxanthin which is considered as super anti-oxidant. Natural astaxanthin produced by H. pluvialis has significantly greater antioxidant capacity than the synthetic one. Astaxanthin has important applications in the nutraceuticals, cosmetics, food, and aquaculture industries. Thanks to many researches it is now evident, that astaxanthin can significantly reduce free radicals and oxidative stress and help human body maintain a healthy state. With extraordinary potency and increase in demand, astaxanthin is one of the high-value microalgal products of the future. Thus, this comprehensive review summarizes the most important aspects of the biology, biochemical composition, biosynthesis and astaxanthin accumulation in the cells of H. pluvialis and its wide range of applications for humans and animals. In this paper, important and recent developments ranging from cultivation, harvest and postharvest bio-processing technologies to metabolic control and genetic engineering are reviewed in detail, focusing on biomass and astaxanthin production from this biotechnologically important microalga. Simultaneously, critical bottlenecks and major challenges in commercial scale production; current and prospective global market of H. pluvialis derived astaxanthin are also presented in a critical manner. A new biorefinery concept for H. pluvialis has been also suggested to guide towards economically sustainable approach for microalgae cultivation and processing. This report could serve as a useful guide to present current status of knowledge in the field and highlight key areas for future development of H. pluvialis astaxanthin technology and its large scale commercial implementation.

  11. The 2017 Plasma Roadmap: Low temperature plasma science and technology

    Science.gov (United States)

    Journal of Physics D: Applied Physics published the first Plasma Roadmap in 2012 consisting of the individual perspectives of 16 leading experts in the various sub-fields of low temperature plasma science and technology. The 2017 Plasma Roadmap is the first update of a planned series of periodic upd...

  12. 76 FR 11308 - Aviation Noise Impacts Roadmap Annual Meeting

    Science.gov (United States)

    2011-03-01

    ... TRANSPORTATION Federal Aviation Administration Aviation Noise Impacts Roadmap Annual Meeting AGENCY: Federal Aviation Administration (FAA), DOT. ACTION: Notice of meeting participation. SUMMARY: This notice advises interested persons that the First Annual Meeting of the Aviation Noise Impacts Roadmap will be held on...

  13. Determination of the behavior and performance of commercial Li-Ion pouch cells by means of isothermal calorimeter

    DEFF Research Database (Denmark)

    Khan, Mohammad Rezwan; Swierczynski, Maciej Jozef; Kær, Søren Knudsen

    2016-01-01

    In this experiment-based research, there is an attempt to determine the evolution of surface temperature distribution, thermal behaviour and performance of a battery cell at the same time. The pouch type commercial test cell has a 13Ah capacity and Lithium Titanate Oxide (LTO) based anode...

  14. Idaho National Engineering Laboratory installation roadmap document. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    1993-05-30

    The roadmapping process was initiated by the US Department of Energy`s office of Environmental Restoration and Waste Management (EM) to improve its Five-Year Plan and budget allocation process. Roadmap documents will provide the technical baseline for this planning process and help EM develop more effective strategies and program plans for achieving its long-term goals. This document is a composite of roadmap assumptions and issues developed for the Idaho National Engineering Laboratory (INEL) by US Department of Energy Idaho Field Office and subcontractor personnel. The installation roadmap discusses activities, issues, and installation commitments that affect waste management and environmental restoration activities at the INEL. The High-Level Waste, Land Disposal Restriction, and Environmental Restoration Roadmaps are also included.

  15. Challenges for Product Roadmapping in Inter-company Collaboration

    Science.gov (United States)

    Suomalainen, Tanja; Tihinen, Maarit; Parviainen, Päivi

    Product roadmapping is a critical activity in product development, as it provides a link between business aspects and requirements engineering and thus helps to manage a high-level view of the company’s products. Nowadays, inter-company collaboration, such as outsourcing, is a common way of developing software products, as through collaboration, organisations gain advantages, such as flexibility with in-house resources, savings in product development costs and gain a physical presence in important markets. The role of product roadmapping becomes even more critical in collaborative settings, since different companies need to align strategies and work together to create products. In order to support companies in improving their own product roadmapping processes, this paper first gives an overview of product roadmapping and then discusses in detail an empirical study of the current practices in industry. The presented results particularly focus on the most challenging and important activities of product roadmapping in collaboration.

  16. A roadmap for educational research in pharmacy.

    Science.gov (United States)

    McLaughlin, Jacqueline E; Dean, Meredith J; Mumper, Russell J; Blouin, Robert A; Roth, Mary T

    2013-12-16

    Educational research must play a critical role in informing practice and policy within pharmacy education. Understanding the educational environment and its impact on students, faculty members, and other stakeholders is imperative for improving outcomes and preparing pharmacy students to meet the needs of 21st century health care. To aid in the design and implementation of meaningful educational research within colleges and schools of pharmacy, this roadmap addresses philosophy and educational language; guidelines for the conduct of educational research; research design, including 4 approaches to defining, collecting, and analyzing educational data; measurement issues; ethical considerations; resources and tools; and the value of educational research in guiding curricular transformation.

  17. Successful user experience strategy and roadmaps

    CERN Document Server

    Rosenzweig, Elizabeth

    2015-01-01

    Successful User Experience: Strategy and Roadmaps provides you with a hands-on guide for pulling all of the User Experience (UX) pieces together to create a strategy that includes tactics, tools, and methodologies. Leveraging material honed in user experience courses and over 25 years in the field, the author explains the value of strategic models to refine goals against available data and resources. You will learn how to think about UX from a high level, design the UX while setting goals for a product or project, and how to turn that into concrete actionable steps. After reading this book, y

  18. Chemicals Industry New Process Chemistry Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2000-08-01

    The Materials Technology I workshop was held in November 1998 to address future research needs for materials technology that will support the chemical industry. Areas covered included disassembly, recovery, reuse and renewable technology; new materials; and materials measurement and characterization. The Materials Technology II workshop was held in September 1999 and covered additives, modeling and prediction and an additional segment on new materials. Materials Technology Institute (MTI) for the Chemical Process Industries, Inc. and Air Products & Chemicals lead the workshops. The Materials Technology Roadmap presents the results from both workshops.

  19. Commercial single-walled carbon nanotubes effects in fibrinolysis of human umbilical vein endothelial cells.

    Science.gov (United States)

    Rodríguez-Yáñez, Yury; Bahena-Uribe, Daniel; Chávez-Munguía, Bibiana; López-Marure, Rebeca; González-Monroy, Stuart; Cisneros, Bulmaro; Albores, Arnulfo

    2015-08-01

    Recent studies have demonstrated that carbon nanotubes (CNTs) induce platelet aggregation, endothelial dysfunction and vascular thrombosis. However, there is little information on the effects of CNTs on fibrinolysis. We investigated the role of pristine-commercial single-walled carbon nanotubes (SWCNTs) with <3% Co content in fibrinolysis and their contribution to the induction of pro-thrombotic processes in human vein endothelial cells (HUVEC). SWCNTs alone produced concentration-dependent oxidation, as measured by a dithiothreitol oxidation assay. Internalized SWCNTs were located in HUVEC treated with 25 μg/ml using transmission electron microscopy, whereas treatment with 50 μg/ml compromised cell viability, and oxidative stress increased significantly at 5 μg/ml. The study showed that in HUVEC treated with 25 μg SWCNT/ml, fibrinolysis-related gene expression and protein levels had increased by 3-12 h after treatment (serpine-1: 13-fold; PLAT: 11-fold and PLAU: 2-fold), but only the PAI-1 protein was increased (1.5-fold), whereas tissue and urokinase plasminogen activator proteins (tPA and uPA, respectively) tended to decrease. In summary, pristine SWCNTs treatment resulted in evident HUVEC damage caused by cell fiber contact, internalization, and oxidative stress due to contaminant metals. The generation of endothelial dysfunction, as shown by the altered expression of genes and proteins involved in fibrinolysis, suggest that SWCNTs display pro-thrombotic effects.

  20. A consortium approach to commercialized Westinghouse solid oxide fuel cell technology

    Science.gov (United States)

    Casanova, Allan

    Westinghouse is developing its tubular solid oxide fuel cells (SOFCs) for a variety of applications in stationary power generation markets. By pressurizing a SOFC and integrating it with a gas turbine (GT), power systems with efficiencies as high as 70-75% can be obtained. The first such system will be tested in 1998. Because of their extraordinarily high efficiency (60-70%) even in small sizes the first SOFC products to be offered are expected to be integrated SOFC/GT power systems in the 1-7 MW range, for use in the emerging distributed generation (DG) market segment. Expansion into larger sizes will follow later. Because of their modularity, environmental friendliness and expected cost effectiveness, and because of a worldwide thrust towards utility deregulation, a ready market is forecasted for baseload distributed generation. Assuming Westinghouse can complete its technology development and reach its cost targets, the integrated SOFC/GT power system is seen as a product with tremendous potential in the emerging distributed generation market. While Westinghouse has been a leader in the development of power generation technology for over a century, it does not plan to manufacture small gas turbines. However, GTs small enough to integrate with SOFCs and address the 1-7 MW market are generally available from various manufacturers. Westinghouse will need access to a new set of customers as it brings baseload plants to the present small market mix of emergency and peaking power applications. Small cogeneration applications, already strong in some parts of the world, are also gaining ground everywhere. Small GT manufacturers already serve this market, and alliances and partnerships can enhance SOFC commercialization. Utilities also serve the DG market, especially those that have set up energy service companies and seek to grow beyond the legal and geographical confines of their current regulated business. Because fuel cells in general are a new product, because small

  1. Technology Roadmap for the 21st Century Truck Program, a government-industry research partnership

    Energy Technology Data Exchange (ETDEWEB)

    None

    2000-12-01

    The 21st Century Truck Program has been established as a government-industry research partnership to support the development and implementation of commercially viable technologies that will dramatically cut fuel use and emissions of commercial trucks and buses while enhancing their safety and affordability as well as maintaining or enhancing performance. The innovations resulting from this program will reduce dependence on foreign oil, improve our nation's air quality, provide advanced technology for military vehicles, and enhance the competitiveness of the U.S. truck and bus industry while ensuring safe and affordable freight and bus transportation for the nation's economy. This Technology Roadmap for the 21st Century Truck Program has been prepared to guide the development of the technical advancements that will enable the needed improvements in commercial truck fuel economy, emissions, and safety.

  2. Technology roadmapping for strategy and innovation charting the route to success

    CERN Document Server

    Isenmann, Ralf; Phaal, Robert

    2013-01-01

    Technology roadmapping is a core method to help companies and other organisations gain orientation for future opportunities and changes. This book is a key resource for technology roadmapping – it provides expert knowledge in four areas: To frame/embed technology roadmapping To structure the process and tasks of technology roadmapping To implement technology roadmapping into corporate strategies To link technology roadmapping to further instruments of strategic planning and corporate foresight This comprehensive survey of technology roadmapping includes papers from leading European, American and Asian experts: It provides an overview of different methods of technology roadmapping and the interactions between them It familiarises readers with the most important sub-methods It embeds/links technology roadmapping to the overall framework of management research and business studies This book, the first of a series, is unique: it aims to become the leading compendium for technology roadmapping knowledge and prac...

  3. Roadmap Carpet 2030; Routekaart Tapijt 2030

    Energy Technology Data Exchange (ETDEWEB)

    Koppert, P. [Verenigde Nederlandse Tapijtfabrikanten VNTF, Zeist (Netherlands); Roemgens, B. [DNV, Bilthoven (Netherlands)

    2012-06-15

    In 2010 a sectoral analysis and market research for living, offices and the care sector were carried out. In 2011, ambitions, formulated in a previous brochure for the carpet sector, were elaborated in this roadmap. It aims at giving direction to strengthening the carpet industry in the field of innovation and sustainability, including the realization of far-reaching energy efficiency. In preparing the roadmap five themes are explored: (1) markets of the future: care sector, office and residential buildings; (2) Health and comfort: indoor climate and maintenance; (3) New materials: bio-based and nano; (4) Flexible production: high-efficient and on-demand; and (5) Return and recycling: collection and qualitative reuse [Dutch] In 2010 zijn een sectoranalyse en marktverkenningen voor wonen, kantoor en zorginstellingen uitgevoerd. De eerdere brochure 'Visie tapijt 2030' beschrijft een richtinggevende visie op de tapijtsector. In 2011 zijn de ambities uit die visie verder uitgewerkt tot deze Routekaart Tapijt 2030 die richting geeft aan het versterken van de tapijtsector op het gebied van innovatie en duurzaamheid, met inbegrip van een vergaande energie-efficiency. Voor het opstellen van de Routekaart zijn vijf thema's uitgewerkt: (1) markten van de toekomst: zorg, kantoren en residentieel; (2) Gezond en gemak: binnenklimaat en onderhoud; (3) Nieuwe materialen: bio-based en nano; (4) Flexibele productie: hoog efficient en on-demand; en (5) Retour en recycling: inzamelen en hoogwaardig hergebruiken.

  4. NASA Net Zero Energy Buildings Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    Pless, S.; Scheib, J.; Torcellini, P.; Hendron, B.; Slovensky, M.

    2014-10-01

    In preparation for the time-phased net zero energy requirement for new federal buildings starting in 2020, set forth in Executive Order 13514, NASA requested that the National Renewable Energy Laboratory (NREL) to develop a roadmap for NASA's compliance. NASA detailed a Statement of Work that requested information on strategic, organizational, and tactical aspects of net zero energy buildings. In response, this document presents a high-level approach to net zero energy planning, design, construction, and operations, based on NREL's first-hand experience procuring net zero energy construction, and based on NREL and other industry research on net zero energy feasibility. The strategic approach to net zero energy starts with an interpretation of the executive order language relating to net zero energy. Specifically, this roadmap defines a net zero energy acquisition process as one that sets an aggressive energy use intensity goal for the building in project planning, meets the reduced demand goal through energy efficiency strategies and technologies, then adds renewable energy in a prioritized manner, using building-associated, emission- free sources first, to offset the annual energy use required at the building; the net zero energy process extends through the life of the building, requiring a balance of energy use and production in each calendar year.

  5. Technology Roadmaps: Carbon Capture and Storage

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-07-01

    Carbon capture and storage (CCS) is an important part of the lowest-cost greenhouse gas (GHG) mitigation portfolio. IEA analysis suggests that without CCS, overall costs to reduce emissions to 2005 levels by 2050 increase by 70%. This roadmap includes an ambitious CCS growth path in order to achieve this GHG mitigation potential, envisioning 100 projects globally by 2020 and over 3000 projects by 2050. This roadmap's level of project development requires an additional investment of over USD 2.5-3 trillion from 2010 to 2050, which is about 6% of the overall investment needed to achieve a 50% reduction in GHG emissions by 2050. OECD governments will need to increase funding for CCS demonstration projects to an average annual level of USD 3.5 to 4 billion (bn) from 2010 to 2020. In addition, mechanisms need to be established to incentivise commercialisation beyond 2020 in the form of mandates, GHG reduction incentives, tax rebates or other financing mechanisms.

  6. Built-Environment Wind Turbine Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    Smith, J.; Forsyth, T.; Sinclair, K.; Oteri, F.

    2012-11-01

    Although only a small contributor to total electricity production needs, built-environment wind turbines (BWTs) nonetheless have the potential to influence the public's consideration of renewable energy, and wind energy in particular. Higher population concentrations in urban environments offer greater opportunities for project visibility and an opportunity to acquaint large numbers of people to the advantages of wind projects on a larger scale. However, turbine failures will be equally visible and could have a negative effect on public perception of wind technology. This roadmap provides a framework for achieving the vision set forth by the attendees of the Built-Environment Wind Turbine Workshop on August 11 - 12, 2010, at the U.S. Department of Energy's National Renewable Energy Laboratory. The BWT roadmap outlines the stakeholder actions that could be taken to overcome the barriers identified. The actions are categorized as near-term (0 - 3 years), medium-term (4 - 7 years), and both near- and medium-term (requiring immediate to medium-term effort). To accomplish these actions, a strategic approach was developed that identifies two focus areas: understanding the built-environment wind resource and developing testing and design standards. The authors summarize the expertise and resources required in these areas.

  7. Technology Roadmap: Carbon Capture and Storage

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-08-01

    As long as fossil fuels and carbon-intensive industries play dominant roles in our economies, carbon capture and storage (CCS) will remain a critical greenhouse gas reduction solution. This CCS roadmap aims at assisting governments and industry in integrating CCS in their emissions reduction strategies and in creating the conditions for scaled-up deployment of all three components of the CCS chain: CO2 capture, transport and storage. To get us onto the right pathway, this roadmap highlights seven key actions needed in the next seven years to create a solid foundation for deployment of CCS starting by 2020. IEA analysis shows that CCS is an integral part of any lowest-cost mitigation scenario where long-term global average temperature increases are limited to significantly less than 4 °C, particularly for 2 °C scenarios (2DS). In the 2DS, CCS is widely deployed in both power generation and industrial applications. The total CO2 capture and storage rate must grow from the tens of megatonnes of CO2 captured in 2013 to thousands of megatonnes of CO2 in 2050 in order to address the emissions reduction challenge. A total cumulative mass of approximately 120 GtCO2 would need to be captured and stored between 2015 and 2050, across all regions of the globe.

  8. Technology Roadmap Research Program for the Steel Industry

    Energy Technology Data Exchange (ETDEWEB)

    Joseph R. Vehec

    2010-12-30

    The steel industry's Technology Roadmap Program (TRP) is a collaborative R&D effort jointly sponsored by the steel industry and the United States Department of Energy. The TRP program was designed to develop new technologies to save energy , increase competitiveness, and improve the environment. TRP ran from July, 1997 to December, 2008, with a total program budget of $38 million dollars. During that period 47 R&D projects were performed by 28 unique research organizations; co-funding was provided by DOE and 60 industry partners. The projects benefited all areas of steelmaking and much know-how was developed and transferred to industry. The American Iron and Steel Institute is the owner of all intellectual property developed under TRP and licenses it at commercial rates to all steelmakers. TRP technologies are in widespread use in the steel industry as participants received royalty-free use of intellectual property in return for taking the risk of funding this research.

  9. Bulk-Heterojunction Organic Solar Cells: Five Core Technologies for Their Commercialization.

    Science.gov (United States)

    Kang, Hongkyu; Kim, Geunjin; Kim, Junghwan; Kwon, Sooncheol; Kim, Heejoo; Lee, Kwanghee

    2016-09-01

    The past two decades of vigorous interdisciplinary approaches has seen tremendous breakthroughs in both scientific and technological developments of bulk-heterojunction organic solar cells (OSCs) based on nanocomposites of π-conjugated organic semiconductors. Because of their unique functionalities, the OSC field is expected to enable innovative photovoltaic applications that can be difficult to achieve using traditional inorganic solar cells: OSCs are printable, portable, wearable, disposable, biocompatible, and attachable to curved surfaces. The ultimate objective of this field is to develop cost-effective, stable, and high-performance photovoltaic modules fabricated on large-area flexible plastic substrates via high-volume/throughput roll-to-roll printing processing and thus achieve the practical implementation of OSCs. Recently, intensive research efforts into the development of organic materials, processing techniques, interface engineering, and device architectures have led to a remarkable improvement in power conversion efficiencies, exceeding 11%, which has finally brought OSCs close to commercialization. Current research interests are expanding from academic to industrial viewpoints to improve device stability and compatibility with large-scale printing processes, which must be addressed to realize viable applications. Here, both academic and industrial issues are reviewed by highlighting historically monumental research results and recent state-of-the-art progress in OSCs. Moreover, perspectives on five core technologies that affect the realization of the practical use of OSCs are presented, including device efficiency, device stability, flexible and transparent electrodes, module designs, and printing techniques.

  10. Uncertainty and innovation: Understanding the role of cell-based manufacturing facilities in shaping regulatory and commercialization environments.

    Science.gov (United States)

    Isasi, Rosario; Rahimzadeh, Vasiliki; Charlebois, Kathleen

    2016-12-01

    The purpose of this qualitative study is to elucidate stakeholder perceptions of, and institutional practices related to cell-based therapies and products (CTP) regulation and commercialization in Canada. The development of reproducible, safe and effective CTPs is predicated on regulatory and commercialization environments that enable innovation. Manufacturing processes constitute a critical step for CTP development in this regard. The road from CTP manufacturing to translation in the clinic, however, has yet to be paved. This study aims to fill an empirical gap in the literature by exploring how CTP manufacturing facilities navigate Canadian regulatory and commercialization environments, which together drive the translation of novel CTPs from bench to bedside. Using the multi-level model of practice-driven institutional change proposed by Smets et al., we demonstrate how CTP manufacturing practices are governed by established standards, yet meaningfully shape higher-order regulatory and commercial norms in CTP research and development. We identify four key themes that undergird such processes of innovation: 1) managing regulatory uncertainty, which stems from an inability to classify CTPs within existing regulatory categories for approval and commercialization purposes; 2) building a 'business case' whereby a CTP's market potential is determined in large part by proving its safety and effectiveness; 3) standardizing manufacturing procedures that mobilize CTPs from a research and development phase to a commercialization one; and 4) networking between researchers and regulators to develop responsible commercialization processes that reflect the uniqueness of CTPs as distinct from other biologics and medical devices.

  11. Breaking down the barriers to commercialization of fuel cells in transportation through Government - industry R&D programs

    Energy Technology Data Exchange (ETDEWEB)

    Chalk, S.G. [Dept. of Energy, Washington, DC (United States); Venkateswaran, S.R. [Energetics, Inc., Columbia, MD (United States)

    1996-12-31

    PEM fuel cell technology is rapidly emerging as a viable propulsion alternative to the internal combustion engine. Fuel cells offer the advantages of low emissions, high efficiency, fuel flexibility, quiet and continuous operation, and modularity. Over the last decade, dramatic advances have been achieved in the performance and cost of PEM fuel cell technologies for automotive applications. However, significant technical barriers remain to making fuel cell propulsion systems viable alternatives to the internal combustion engine. This paper focuses on the progress achieved and remaining technical barriers while highlighting Government-industry R&D efforts that are accelerating fuel cell technology toward commercialization.

  12. The European Hematology Association Roadmap for European Hematology Research: a consensus document.

    Science.gov (United States)

    Engert, Andreas; Balduini, Carlo; Brand, Anneke; Coiffier, Bertrand; Cordonnier, Catherine; Döhner, Hartmut; de Wit, Thom Duyvené; Eichinger, Sabine; Fibbe, Willem; Green, Tony; de Haas, Fleur; Iolascon, Achille; Jaffredo, Thierry; Rodeghiero, Francesco; Salles, Gilles; Schuringa, Jan Jacob

    2016-02-01

    The European Hematology Association (EHA) Roadmap for European Hematology Research highlights major achievements in diagnosis and treatment of blood disorders and identifies the greatest unmet clinical and scientific needs in those areas to enable better funded, more focused European hematology research. Initiated by the EHA, around 300 experts contributed to the consensus document, which will help European policy makers, research funders, research organizations, researchers, and patient groups make better informed decisions on hematology research. It also aims to raise public awareness of the burden of blood disorders on European society, which purely in economic terms is estimated at €23 billion per year, a level of cost that is not matched in current European hematology research funding. In recent decades, hematology research has improved our fundamental understanding of the biology of blood disorders, and has improved diagnostics and treatments, sometimes in revolutionary ways. This progress highlights the potential of focused basic research programs such as this EHA Roadmap.The EHA Roadmap identifies nine 'sections' in hematology: normal hematopoiesis, malignant lymphoid and myeloid diseases, anemias and related diseases, platelet disorders, blood coagulation and hemostatic disorders, transfusion medicine, infections in hematology, and hematopoietic stem cell transplantation. These sections span 60 smaller groups of diseases or disorders.The EHA Roadmap identifies priorities and needs across the field of hematology, including those to develop targeted therapies based on genomic profiling and chemical biology, to eradicate minimal residual malignant disease, and to develop cellular immunotherapies, combination treatments, gene therapies, hematopoietic stem cell treatments, and treatments that are better tolerated by elderly patients.

  13. Program of scientific investigations and development of solid-oxide fuel cells (SOFC) in VIITF proposals on scientific and technical collaboration and SOFC commercialization

    Energy Technology Data Exchange (ETDEWEB)

    Kleschev, Yu.N.; Chulharev, V.F.

    1996-04-01

    Investigations being performed at VNIITF covers the whole cycle of solid oxide fuel cell manufacturing. This report describes the main directions of investigations in materials, technologies, and commercialization.

  14. Employing Hot Wire Anemometry to Directly Measure the Water Balance of a Commercial Proton Exchange Membrane Fuel Cell Stack

    DEFF Research Database (Denmark)

    Shakhshir, Saher Al; Berning, Torsten

    2016-01-01

    Proton exchange membrane fuel cells (PEMFC’s) are currently being commercialized for various applications ranging from automotive (e.g. the Toyota Mirai) to stationary such as powering telecom backup units. In PEMFC’s, oxygen from air is internally combined with hydrogen to form water and produce...

  15. A Tool Design of Cobit Roadmap Implementation

    Directory of Open Access Journals (Sweden)

    Karim Youssfi

    2014-08-01

    Full Text Available Over the last two decades, the role of information technology in organizations has changed from primarily a supportive and transactional function to being an essential prerequisite for strategic value generation. The organizations based their operational services through its Information Systems (IS that need to be managed, controlled and monitored constantly. IT governance (ITG, i.e. the way organizations manage IT resources, has became a key factor for enterprise success due to the increasing enterprise dependency on IT solutions. There are several approaches available to deal with ITG. These methods are diverse, and in some cases, long and complicated to implement. One well-accepted ITG framework is COBIT, designed for a global approach. This paper describes a design of a tool for COBIT roadmap implementation. The model is being developed in the course of ongoing PhD research.

  16. Background paper on Technology Roadmaps (TRMs)

    Energy Technology Data Exchange (ETDEWEB)

    More, E.; Phaal, R. [Institute for Manufacturing IfM, Department of Engineering, University of Cambridge, Cambridge (United Kingdom); Londo, H.M.; Wurtenberger, L.; Cameron, L.R. [ECN Policy Studies, Amsterdam (Netherlands)

    2013-04-15

    This background paper reports on the use of technology roadmaps (TRMs) related to climate change mitigation and adaptation technologies. The study is motivated by the UNFCCC Conference of the Parties (CoP) request to the Technology Executive Committee (TEC) to catalyse the development and use of TRMs as facilitative tools for action on mitigation and adaptation. Having originated in industry, TRMs are now used extensively in policy settings too, however their widespread use across sectors and by different stakeholders has resulted in a lack of understanding of their real value to help catalyse cooperation towards technological solutions to the problems presented by climate change. Consequently this background paper presents (1) an overview of different TRM methods, (2) an initial analysis of gaps and barriers in existing TRMs, and (3) a review of current TRM good practices.

  17. Roadmap ICT 2030; Routekaart ICT 2030

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-06-15

    Extra attention for 'ICT and energy' can lead to significant energy savings, both in the ICT sector (Greening of ICT), as in other sectors (Greening by ICT). That has been elaborated as a vision of ICT Office in this roadmap. Actions are formulated to get started. Innovations and measures are connected to energy saving targets [Dutch] Extra aandacht voor 'ICT en energie' kan leiden tot grote energiebesparingen, zowel in de ICT sector zelf (Greening of ICT), als in andere sectoren (Greening by ICT). Dat is in deze Routekaart als visie van ICT-Office uitgewerkt. Acties zijn geformuleerd om daadwerkelijk aan de slag te kunnen gaan. Aan de innovaties en maatregelen zijn doelstellingen ten aanzien van energiebesparing gekoppeld, die zijn vertaald naar concrete bedragen.

  18. Roadmap to the SRS computing architecture

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, A.

    1994-07-05

    This document outlines the major steps that must be taken by the Savannah River Site (SRS) to migrate the SRS information technology (IT) environment to the new architecture described in the Savannah River Site Computing Architecture. This document proposes an IT environment that is {open_quotes}...standards-based, data-driven, and workstation-oriented, with larger systems being utilized for the delivery of needed information to users in a client-server relationship.{close_quotes} Achieving this vision will require many substantial changes in the computing applications, systems, and supporting infrastructure at the site. This document consists of a set of roadmaps which provide explanations of the necessary changes for IT at the site and describes the milestones that must be completed to finish the migration.

  19. Advanced Modeling, Simulation and Analysis (AMSA) Capability Roadmap Progress Review

    Science.gov (United States)

    Antonsson, Erik; Gombosi, Tamas

    2005-01-01

    Contents include the following: NASA capability roadmap activity. Advanced modeling, simulation, and analysis overview. Scientific modeling and simulation. Operations modeling. Multi-special sensing (UV-gamma). System integration. M and S Environments and Infrastructure.

  20. Business Case for a Micro-Combined Heat and Power Fuel Cell System in Commercial Applications

    Energy Technology Data Exchange (ETDEWEB)

    Brooks, Kriston P.; Makhmalbaf, Atefe; Anderson, David M.; Amaya, Jodi P.; Pilli, Siva Prasad; Srivastava, Viraj; Upton, Jaki F.

    2013-10-30

    Combined heat and power fuel cell systems (CHP-FCSs) provide consistent electrical power and hot water with greater efficiency and lower emissions than alternative sources. These systems can be used either as baseload, grid-connected, or as off-the-grid power sources. This report presents a business case for CHP-FCSs in the range of 5 to 50 kWe. Systems in this power range are considered micro-CHP-FCS. For this particular business case, commercial applications rather than residential or industrial are targeted. To understand the benefits of implementing a micro-CHP-FCS, the characteristics that determine their competitive advantage must first be identified. Locations with high electricity prices and low natural gas prices are ideal locations for micro-CHP-FCSs. Fortunately, these high spark spread locations are generally in the northeastern area of the United States and California where government incentives are already in place to offset the current high cost of the micro-CHP-FCSs. As a result of the inherently high efficiency of a fuel cell and their ability to use the waste heat that is generated as a CHP, they have higher efficiency. This results in lower fuel costs than comparable alternative small-scale power systems (e.g., microturbines and reciprocating engines). A variety of markets should consider micro-CHP-FCSs including those that require both heat and baseload electricity throughout the year. In addition, the reliable power of micro-CHP-FCSs could be beneficial to markets where electrical outages are especially frequent or costly. Greenhouse gas emission levels from micro-CHP-FCSs are 69 percent lower, and the human health costs are 99.9 percent lower, than those attributed to conventional coal-fired power plants. As a result, FCSs can allow a company to advertise as environmentally conscious and provide a bottom-line sales advantage. As a new technology in the early stages of adoption, micro-CHP-FCSs are currently more expensive than alternative

  1. Design of serum-free medium for suspension culture of CHO cells on the basis of general commercial media.

    Science.gov (United States)

    Miki, Hideo; Takagi, Mutsumi

    2015-08-01

    The design of serum-free media for suspension culture of genetically engineered Chinese hamster ovary (CHO) cells using general commercial media as a basis was investigated. Subcultivation using a commercial serum-free medium containing insulin-like growth factor (IGF)-1 with or without FCS necessitated additives other than IGF-1 to compensate for the lack of FCS and improve cell growth. Suspension culture with media containing several combinations of growth factors suggested the effectiveness of addition of both IGF-1 and the lipid signaling molecule lysophosphatidic acid (LPA) for promoting cell growth. Subcultivation of CHO cells in suspension culture using the commercial serum-free medium EX-CELL™302, which contained an IGF-1 analog, supplemented with LPA resulted in gradually increasing specific growth rate comparable to the serum-containing medium and in almost the same high antibody production regardless of the number of generations. The culture with EX-CELL™302 supplemented with LPA in a jar fermentor with pH control at 6.9 showed an apparently higher cell growth rate than the cultures without pH control and with pH control at 6.8. The cell growth in the medium supplemented with aurintricarboxylic acid (ATA), which was much cheaper than IGF-1, in combination with LPA was synergistically promoted similarly to that in the medium supplemented with IGF-1 and LPA. In conclusion, the serum-free medium designed on the basis of general commercial media could support the growth of CHO cells and antibody production comparable to serum-containing medium in suspension culture. Moreover, the possibility of cost reduction by the substitution of IGF-1 with ATA was also shown.

  2. CD1c-Expression by Monocytes - Implications for the Use of Commercial CD1c+ Dendritic Cell Isolation Kits.

    Directory of Open Access Journals (Sweden)

    Martine Schrøder

    Full Text Available Conventional dendritic cells (cDCs comprise a heterogeneous population of cells that are important regulators of immunity and homeostasis. CD1c+ cDCs are present in human blood and tissues, and found to efficiently activate naïve CD4+ T cells. While CD1c is thought to specifically identify this subset of human cDCs, we show here that also classical and intermediate monocytes express CD1c. Accordingly, the commercial CD1c (BDCA-1+ Dendritic Cell Isolation Kit isolates two distinct cell populations from blood: CD1c+CD14- cDCs and CD1c+CD14+ monocytes. CD1c+ cDCs and CD1c+ monocytes exhibited strikingly different properties, including their differential regulation of surface marker expression, their levels of cytokine production, and their ability to stimulate naïve CD4+ T cells. These results demonstrate that a commercial CD1c (BDCA-1+ Dendritic Cell Isolation Kit isolates two functionally different cell populations, which has important implications for the interpretation of previously generated data using this kit to characterize CD1c+ cDCs.

  3. Community resources and technologies developed through the NIH Roadmap Epigenomics Program.

    Science.gov (United States)

    Satterlee, John S; Beckel-Mitchener, Andrea; McAllister, Kim; Procaccini, Dena C; Rutter, Joni L; Tyson, Frederick L; Chadwick, Lisa Helbling

    2015-01-01

    This chapter describes resources and technologies generated by the NIH Roadmap Epigenomics Program that may be useful to epigenomics researchers investigating a variety of diseases including cancer. Highlights include reference epigenome maps for a wide variety of human cells and tissues, the development of new technologies for epigenetic assays and imaging, the identification of novel epigenetic modifications, and an improved understanding of the role of epigenetic processes in a diversity of human diseases. We also discuss future needs in this area including exploration of epigenomic variation between individuals, single-cell epigenomics, environmental epigenomics, exploration of the use of surrogate tissues, and improved technologies for epigenome manipulation.

  4. Design of Mechanical Properties of Open-Cell Porous Materials Based on μCT Study of Commercial Foams

    Directory of Open Access Journals (Sweden)

    Skibinski Jakub

    2015-01-01

    Full Text Available In the present paper numerical design of mechanical properties of open-cell porous materials is addressed. A detailed knowledge of mechanisms and parameters determining mechanical properties (i.e. Young’s Modulus, Poisson’s Ratio of foams is essential for applications such as energy absorbers or lightweight construction materials. The foam structures were designed using procedure based on Laguerre-Voronoi tessellations (LVT with micro-computed tomography of commercial foams used as reference. Foam morphology was studied on post-processed computed tomography images and the parameters of LVT structures were compared with commercial materials. Subsequently finite element method (FEM calculations were performed on both types of structures to validate the LVT design algorithm. The results show that the described design procedure can be successfully used for modeling mechanical properties of open-cell foam structures.

  5. SQUIDs in biomagnetism: a roadmap towards improved healthcare

    Science.gov (United States)

    Körber, Rainer; Storm, Jan-Hendrik; Seton, Hugh; Mäkelä, Jyrki P.; Paetau, Ritva; Parkkonen, Lauri; Pfeiffer, Christoph; Riaz, Bushra; Schneiderman, Justin F.; Dong, Hui; Hwang, Seong-min; You, Lixing; Inglis, Ben; Clarke, John; Espy, Michelle A.; Ilmoniemi, Risto J.; Magnelind, Per E.; Matlashov, Andrei N.; Nieminen, Jaakko O.; Volegov, Petr L.; Zevenhoven, Koos C. J.; Höfner, Nora; Burghoff, Martin; Enpuku, Keiji; Yang, S. Y.; Chieh, Jen-Jei; Knuutila, Jukka; Laine, Petteri; Nenonen, Jukka

    2016-11-01

    to its corresponding antigen, if it is present. Any resulting changes in the properties of the nanoparticles are detected with a SQUID. For liquid-phase detection, there are three basic methods: AC susceptibility, magnetic relaxation and remanence measurement. These methods, which have been successfully implemented for both in vivo and ex vivo applications, are highly sensitive and, although further development is required, it appears highly likely that at least some of them will be commercialized. Chapter 8 concludes the roadmap with an assessment of the commercial market for MEG systems. Despite the huge advances that have been realized since MEG was first introduced, the number of commercial systems deployed around the world remains small, around 250 units employing about 50 000 SQUIDs. The slow adoption of this technology is undoubtedly in part due to the high cost, not least because of the need to surround the entire system in an expensive magnetically shielded room. Nonetheless, the recent introduction of automatically refilling liquid-helium systems, the ongoing reduction in sensor noise, the potential availability of high-T c SQUID systems, the availability of new and better software and the combination of MEG with ULF MRI all have the potential to increase the market size in the not-so-distant future. In particular, there is a great and growing need for better noninvasive technologies to measure brain function. There are hundreds of millions of people in the world who suffer from brain disorders such as epilepsy, stroke, dementia or depression. The enormous cost to society of these diseases can be reduced by earlier and more accurate detection and diagnosis. Once the challenges outlined in this roadmap have been met and the outstanding problems have been solved, the potential demand for SQUID-based health technology can be expected to increase by ten- if not hundred-fold.

  6. Technology Roadmap: Fuel Economy of Road Vehicles

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-07-01

    This roadmap explores the potential improvement of existing technologies to enhance the average fuel economy of motorised vehicles; the roadmap’s vision is to achieve a 30% to 50% reduction in fuel use per kilometre from new road vehicles including 2-wheelers, LDV s and HDV s) around the world in 2030, and from the stock of all vehicles on the road by 2050. This achievement would contribute to significant reductions in GHG emissions and oil use, compared to a baseline projection. Different motorised modes are treated separately, with a focus on LDV s, HDV s and powered two-wheelers. A section on in-use fuel economy also addresses technical and nontechnical parameters that could allow fuel economy to drastically improve over the next decades. Technology cost analysis and payback time show that significant progress can be made with low or negative cost for fuel-efficient vehicles over their lifetime use. Even though the latest data analysed by the IEA for fuel economy between 2005 and 2008 showed that a gap exists in achieving the roadmap’s vision, cutting the average fuel economy of road motorised vehicles by 30% to 50% by 2030 is achievable, and the policies and technologies that could help meet this challenge are already deployed in many places around the world.

  7. AFCI Safeguards Enhancement Study: Technology Development Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    Smith, Leon E.; Dougan, A.; Tobin, Stephen; Cipiti, B.; Ehinger, Michael H.; Bakel, A. J.; Bean, Robert; Grate, Jay W.; Santi, P.; Bryan, Steven; Kinlaw, M. T.; Schwantes, Jon M.; Burr, Tom; Lehn, Scott A.; Tolk, K.; Chichester, David; Menlove, H.; Vo, D.; Duckworth, Douglas C.; Merkle, P.; Wang, T. F.; Duran, F.; Nakae, L.; Warren, Glen A.; Friedrich, S.; Rabin, M.

    2008-12-31

    The Advanced Fuel Cycle Initiative (AFCI) Safeguards Campaign aims to develop safeguards technologies and processes that will significantly reduce the risk of proliferation in the U.S. nuclear fuel cycle of tomorrow. The Safeguards Enhancement Study was chartered with identifying promising research and development (R&D) directions over timescales both near-term and long-term, and under safeguards oversight both domestic and international. This technology development roadmap documents recognized gaps and needs in the safeguarding of nuclear fuel cycles, and outlines corresponding performance targets for each of those needs. Drawing on the collective expertise of technologists and user-representatives, a list of over 30 technologies that have the potential to meet those needs was developed, along with brief summaries of each candidate technology. Each summary describes the potential impact of that technology, key research questions to be addressed, and prospective development milestones that could lead to a definitive viability or performance assessment. Important programmatic linkages between U.S. agencies and offices are also described, reflecting the emergence of several safeguards R&D programs in the U.S. and the reinvigoration of nuclear fuel cycles across the globe.

  8. The Netherlands Roadmap for Large-scale Research Facilities; Nederlandse Roadmap Grootschalige Onderzoeksfaciliteiten

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-10-15

    Large-scale research facilities are of inestimable strategic value for science and research and, hence, for the Dutch knowledge economy. In July 2007, the Dutch Minister of Education, Culture and Science set up the National Roadmap Committee for Large-Scale Research Facilities, whose main task was to advise him as to which large-scale research facilities the Netherlands should construct or participate in within an international context. In the present advisory report, the Committee presents 25 large-scale research facilities whose construction or operation the Committee believes is important for the robustness and innovativeness of the Dutch science system. [Dutch] Grootschalige onderzoeksfaciliteiten zijn van onschatbaar strategisch belang voor onderzoek en wetenschap en daarmee voor de Nederlandse kenniseconomie. De Minister van OCW heeft in juli 2007 de Commissie Nationale Roadmap Grootschalige Onderzoeksfaciliteiten ingesteld met het primaire doel hem te adviseren welke grootschalige onderzoeksfaciliteiten geschikt zijn om in Nederland zelf te bouwen of om in een internationale context aan mee te doen. De Commissie presenteert in dit advies 25 grootschalige onderzoeksfaciliteiten waarvan naar het oordeel van de Commissie de bouw en exploitatie van belang zijn voor de vitaliteit en het innovatief vermogen van het Nederlandse wetenschap systeem.

  9. Continuing the International Roadmapping Effort - An Introduction to the Evolution of the ISECG Global Exploration Roadmap

    Science.gov (United States)

    Schlutz, Juergen; Hufenbach, Bernhard; Laurini, Kathy; Spiero, Francois

    2016-07-01

    Future space exploration goals call for sending humans and robots beyond low Earth orbit and establishing sustained access to destinations such as the Moon, asteroids and Mars. Space agencies participating in the International Space Exploration Coordination Group (ISECG) are discussing an international approach for achieving these goals, documented in ISECG's Global Exploration Roadmap (GER). The GER reference scenario reflects a step-wise evolution of critical capabilities from ISS to missions in the lunar vicinity in preparation for the journey of humans to Mars. As ISECG agencies advance their individual planning, they also advance the mission themes and reference architecture of the GER to consolidate common goals, near-term mission scenarios and initial opportunities for collaboration. In this context, particular focus has been given to the Better understanding and further refinement of cislunar infrastructure and potential lunar transportation architecture Interaction with international science communities to identify and articulate the scientific opportunities of the near-term exploration mission themes Coordination and consolidation of interest in lunar polar volatiles prospecting and potential for in-situ resource utilisation Identification and articulation of the benefits from exploration and the technology transfer activities The paper discusses the ongoing roadmapping activity of the ISECG agencies. It provides an insight into the status of the above activities and an outlook towards the evolution of the GER that is currently foreseen in the 2017 timeframe.

  10. 3D roadmap in neuroangiography: technique and clinical interest

    Energy Technology Data Exchange (ETDEWEB)

    Soederman, Michael; Andersson, T. [Karolinska Hospital, Department of Neuroradiology, Stockholm (Sweden); Babic, D.; Homan, R. [Philips Medical Systems, Best (Netherlands)

    2005-10-01

    We present the first clinical results obtained with a novel technique: the three-dimensional [3D] roadmap. The major difference from the standard 2D digital roadmap technique is that the newly developed 3D roadmap is based on a rotational angiography acquisition technique with the two-dimensional [2D] fluoroscopic image as an overlay. Data required for an accurate superimposition of the previously acquired 3D reconstructed image on the interactively made 2D fluoroscopy image, in real time, are stored in the 3D workstation and constitute the calibration dataset. Both datasets are spatially aligned in real time; thus, the 3D image is accurately superimposed on the 2D fluoroscopic image regardless of any change in C-arm position or magnification. The principal advantage of the described roadmap method is that one contrast injection allows the C-arm to be positioned anywhere in the space and allows alterations in the distance between the x-ray tube and the image intensifier as well as changes in image magnification. In the clinical setting, the 3D roadmap facilitated intravascular neuronavigation with concurrent reduction of procedure time and use of contrast medium. (orig.)

  11. Research and development of Proton-Exchange-Membrane (PEM) fuel cell system for transportation applications. Fuel cell infrastructure and commercialization study

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-11-01

    This paper has been prepared in partial fulfillment of a subcontract from the Allison Division of General Motors under the terms of Allison`s contract with the U.S. Department of Energy (DE-AC02-90CH10435). The objective of this task (The Fuel Cell Infrastructure and Commercialization Study) is to describe and prepare preliminary evaluations of the processes which will be required to develop fuel cell engines for commercial and private vehicles. This report summarizes the work undertaken on this study. It addresses the availability of the infrastructure (services, energy supplies) and the benefits of creating public/private alliances to accelerate their commercialization. The Allison prime contract includes other tasks related to the research and development of advanced solid polymer fuel cell engines and preparation of a demonstration automotive vehicle. The commercialization process starts when there is sufficient understanding of a fuel cell engine`s technology and markets to initiate preparation of a business plan. The business plan will identify each major step in the design of fuel cell (or electrochemical) engines, evaluation of the markets, acquisition of manufacturing facilities, and the technical and financial resources which will be required. The process will end when one or more companies have successfully developed and produced fuel cell engines at a profit. This study addressed the status of the information which will be required to prepare business plans, develop the economic and market acceptance data, and to identify the mobility, energy and environment benefits of electrochemical or fuel cell engines. It provides the reader with information on the status of fuel cell or electrochemical engine development and their relative advantages over competitive propulsion systems. Recommendations and descriptions of additional technical and business evaluations that are to be developed in more detail in Phase II, are included.

  12. ESTABLISH A CREATIVE ENVIRONMENT FOR ROADMAPPING IN ACADEMY- FROM THE PERSPECTIVE OF I-SYSTEM METHODOLOGY

    Institute of Scientific and Technical Information of China (English)

    Tieju MA; Andrzej P. WIERZBICKI; Yoshiteru NAKAMORI

    2007-01-01

    Roadmapping, originated from industry as a strategic planning tool, is attracting increasing applications in academy. Based on the recognition that roadmapping is a knowledge creation process,this paper analyzes what kind of support is needed or helpful for establishing a creative environment for roadmapping in academy and reviews various types of such support from the perspective of i-system methodology. As case studies of such support, this paper further introduces roadmapping pratices in Janpan Advanced Institute of Science and Technology.

  13. PVT roadmap. A European guide for the development and market introduction of PVT technology

    Energy Technology Data Exchange (ETDEWEB)

    Zondag, H.A.; Van Helden, W.G.J.; Bakker, M. [ECN Renewable Energy in the Built Environment DEGO, Petten (Netherlands); Affolter, P. [Solstis, Lausanne (Switzerland); Eisenmann, W. [Institut fuer Solarenergieforschung ISFH, Emmerthal (Germany); Fechner, H. [Arsenal Research, Vienna (Austria); Rommel, M. [Fraunhofer ISE, Freiburg (Germany); Schaap, A. [Ecofys, Utrecht (Netherlands); Soerensen, H. [Esbensen, Copenhagen (Denmark); Tripanagnostopoulos, Y. [University of Patras, Patras (Greece)

    2005-11-15

    In PVT technology, heat is extracted from PV cells. In this way, a device is made that produces both electricity and heat. In the EU-funded co-ordination action PV-Catapult, workshops on PVT were organised at the PVSEC 2004 Conference in Paris and the Eurosun 2004 conference in Freiburg, to obtain active participation of the PV and solar thermal communities. Currently, the results of the workshops are used in the drafting of a roadmap for the large-scale introduction of PVT technology on the market. First results will be presented here.

  14. A roadmap for the development and market introduction of PVT technology

    Energy Technology Data Exchange (ETDEWEB)

    Zondag, H.A.; Van Helden, W.G.J.; Bakker, M.; Elswijk, M.J. [ECN Renewable Energy in the Built Environment DEGO, Petten (Netherlands)

    2005-11-15

    In PVT technology, heat is extracted from PV cells. In this way, a device is made that produces both electricity and heat. In the EU funded coordination action PV-Catapult, workshops on PVT were organised at the PVSEC 2004 Conference in Paris and the Eurosun 2004 conference in Freiburg, to obtain active participation of the PV and solar thermal communities. Currently, the results of the workshops are used in the drafting of a roadmap for the large scale introduction of PVT technology on the market. First results will be presented here.

  15. Superconductivity and the environment: a Roadmap

    Science.gov (United States)

    Nishijima, Shigehiro; Eckroad, Steven; Marian, Adela; Choi, Kyeongdal; Kim, Woo Seok; Terai, Motoaki; Deng, Zigang; Zheng, Jun; Wang, Jiasu; Umemoto, Katsuya; Du, Jia; Febvre, Pascal; Keenan, Shane; Mukhanov, Oleg; Cooley, Lance D.; Foley, Cathy P.; Hassenzahl, William V.; Izumi, Mitsuru

    2013-11-01

    There is universal agreement between the United Nations and governments from the richest to the poorest nations that humanity faces unprecedented global challenges relating to sustainable energy, clean water, low-emission transportation, coping with climate change and natural disasters, and reclaiming use of land. We have invited researchers from a range of eclectic research areas to provide a Roadmap of how superconducting technologies could address these major challenges confronting humanity. Superconductivity has, over the century since its discovery by Kamerlingh Onnes in 1911, promised to provide solutions to many challenges. So far, most superconducting technologies are esoteric systems that are used in laboratories and hospitals. Large science projects have long appreciated the ability of superconductivity to efficiently create high magnetic fields that are otherwise very costly to achieve with ordinary materials. The most successful applications outside of large science are high-field magnets for magnetic resonance imaging, laboratory magnetometers for mineral and materials characterization, filters for mobile communications, and magnetoencephalography for understanding the human brain. The stage is now set for superconductivity to make more general contributions. Humanity uses practically unthinkable amounts of energy to drive our modern way of life. Overall, global power usage has been predicted to almost double from 16.5 to 30 TW in the next four decades (2011 Equinox Summit: Energy 2030 http://wgsi.org/publications-resources). The economy with which electrons carry energy compels the continued quest for efficient superconducting power generation, energy storage, and power transmission. The growing global population requires new arable land and treatment of water, especially in remote areas, and superconductivity offers unique solutions to these problems. Exquisite detectors give warning of changes that are otherwise invisible. Prediction of climate and

  16. Technology Roadmaps: A guide to development and implementation

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-07-01

    New low-carbon technologies show clear potential for transforming the global energy system, but a key challenge remains: what steps do governments and industry need to take to ensure their development and deployment? Roadmapping, used for decades in technology-intensive industries, is a useful tool to help address complicated issues strategically at the national, regional and global levels. To help turn political statements and analytical work into concrete action, the International Energy Agency (IEA) is developing a series of global roadmaps devoted to low-carbon energy technologies. This guide is aimed at providing countries and companies with the context, information and tools they need to design, manage and implement an effective energy roadmap process.

  17. A Research Roadmap for Complementary and Alternative Medicine

    DEFF Research Database (Denmark)

    Fischer, F.; Lewith, G.; Witt, C. M.

    2014-01-01

    questions, study design and the assurance of real-world relevance for the research. Furthermore, structural and sufficient financial support for research into CAM is needed to strengthen CAM research capacity if we wish to understand why it remains so popular within the EU. In order to consider employing...... about CAM, both positive and negative. This roadmap proposes a strategic research agenda for the field of CAM designed to address future European health care challenges. This roadmap is based on the results of CAMbrella's several work packages, literature reviews and expert discussions including......, Sweden, May 9-11th 2012) with all CAMbrella members and the CAMbrella advisory board. The roadmap was revised after this discussion in CAMbrella Work Package (WP) 7 and finally approved by CAMbrella's scientific steering committee on September 26th 2012. Results: Our main findings show that CAM is very...

  18. An Interim Report on NASA's Draft Space Technology Roadmaps

    Science.gov (United States)

    2011-01-01

    NASA has developed a set of 14 draft roadmaps to guide the development of space technologies under the leadership of the NASA Office of the Chief Technologist (OCT). Each of these roadmaps focuses on a particular technology area (TA). The roadmaps are intended to foster the development of advanced technologies and concepts that address NASA's needs and contribute to other aerospace and national needs. OCT requested that the National Research Council conduct a study to review the draft roadmaps, gather and assess relevant community input, and make recommendations and suggest priorities to inform NASA's decisions as it finalizes its roadmaps. The statement of task states that "based on the results of the community input and its own deliberations, the steering committee will prepare a brief interim report that addresses high-level issues associated with the roadmaps, such as the advisability of modifying the number or technical focus of the draft NASA roadmaps." This interim report, which does not include formal recommendations, addresses that one element of the study charge. NASA requested this interim report so that it would have the opportunity to make an early start in modifying the draft roadmaps based on feedback from the panels and steering committee. The final report will address all other tasks in the statement of task. In particular, the final report will include a prioritization of technologies, will describe in detail the prioritization process and criteria, and will include specific recommendations on a variety of topics, including many of the topics mentioned in this interim report. In developing both this interim report and the final report to come, the steering committee draws on the work of six study panels organized by technical area, loosely following the organization of the 14 roadmaps, as follows: A Panel 1: Propulsion and Power TA01 Launch Propulsion Systems TA02 In-Space Propulsion Technologies TA03 Space Power and Energy Storage Systems TA13

  19. Indonesia ergonomics roadmap: where we are going?

    Science.gov (United States)

    Wignjosoebroto, Sritomo

    2007-12-01

    There are so many definitions for ergonomics terms such as human factors, human factors engineering, human engineering, human factors psychology, engineering psychology, applied ergonomics, occupational ergonomics, industrial ergonomics and industrial engineering. The most inclusive terms are ergonomics and human factors. Both represent the study of work and the interaction between people and their work environmental systems. The main objective is especially fitting with the need to design, develop, implement and evaluate human-machine and environment systems that are productive, comfortable, safe and satisfying to use. The work of the ergonomists in Indonesia--most of them are academicians--have one thing in common, i.e. with the appropriate type of ergonomic approaches to interventions; there would be improvements in productivity, quality of working conditions, occupational safety and health (OSH), costs reduction, better environment, and increase in profits. So many researches, training, seminars and socialization about ergonomics and OSH have been done concerning micro-to-macro themes; but it seems that we are practically still running at the same place up to now. In facts, workers are still working using their traditional or obsolete methods in poor working conditions. Accidents are still happening inside and outside industry with the main root-cause being human "unsafe behavior" and errors. Industrial products cannot compete in the global market, and so many manufacturing industries collapsed or relocated to foreign countries. This paper discusses such a roadmap and review what we ergonomists in Indonesia have done and where we are going to? This review will be treated in the field of ergonomics and OSH to take care the future Indonesia challenges. Some of the challenges faced are care for the workers, care for the people, care for the quality and productivity of work, care for the new advanced technologies, care for the environment, and last but not least

  20. Food for thought ... A toxicology ontology roadmap.

    Science.gov (United States)

    Hardy, Barry; Apic, Gordana; Carthew, Philip; Clark, Dominic; Cook, David; Dix, Ian; Escher, Sylvia; Hastings, Janna; Heard, David J; Jeliazkova, Nina; Judson, Philip; Matis-Mitchell, Sherri; Mitic, Dragana; Myatt, Glenn; Shah, Imran; Spjuth, Ola; Tcheremenskaia, Olga; Toldo, Luca; Watson, David; White, Andrew; Yang, Chihae

    2012-01-01

    Foreign substances can have a dramatic and unpredictable adverse effect on human health. In the development of new therapeutic agents, it is essential that the potential adverse effects of all candidates be identified as early as possible. The field of predictive toxicology strives to profile the potential for adverse effects of novel chemical substances before they occur, both with traditional in vivo experimental approaches and increasingly through the development of in vitro and computational methods which can supplement and reduce the need for animal testing. To be maximally effective, the field needs access to the largest possible knowledge base of previous toxicology findings, and such results need to be made available in such a fashion so as to be interoperable, comparable, and compatible with standard toolkits. This necessitates the development of open, public, computable, and standardized toxicology vocabularies and ontologies so as to support the applications required by in silico, in vitro, and in vivo toxicology methods and related analysis and reporting activities. Such ontology development will support data management, model building, integrated analysis, validation and reporting, including regulatory reporting and alternative testing submission requirements as required by guidelines such as the REACH legislation, leading to new scientific advances in a mechanistically-based predictive toxicology. Numerous existing ontology and standards initiatives can contribute to the creation of a toxicology ontology supporting the needs of predictive toxicology and risk assessment. Additionally, new ontologies are needed to satisfy practical use cases and scenarios where gaps currently exist. Developing and integrating these resources will require a well-coordinated and sustained effort across numerous stakeholders engaged in a public-private partnership. In this communication, we set out a roadmap for the development of an integrated toxicology ontology

  1. Summary of the International Workshop on Magnetic Fusion Energy (MFE) Roadmapping in the ITER Era; 7-10 September 2011, Princeton, NJ, USA

    Science.gov (United States)

    Neilson, G. H.; Federici, G.; Li, J.; Maisonnier, D.; Wolf, R.

    2012-04-01

    With the ITER project now well under way, the countries engaged in fusion research are planning, with renewed intensity, the research and major facilities needed to develop the science and technology for harnessing fusion energy. The Workshop on MFE Roadmapping in the ITER Era was organized to provide a timely forum for an international exchange of technical information and strategic perspectives on how best to tackle the remaining challenges leading to a magnetic fusion DEMO, a nuclear fusion device or devices with a level of physics and technology integration necessary to cover the essential elements of a commercial fusion power plant. Presentations addressed issues under four topics: (1) Perspectives on DEMO and the roadmap to DEMO; (2) Technology; (3) Physics-Technology integration and optimization; and (4) Major facilities on the path to DEMO. Participants identified a set of technical issues of high strategic importance, where the development strategy strongly influences the overall roadmap, and where there are divergent understandings in the world community, namely (1) the assumptions used in fusion design codes, (2) the strategy for fusion materials development, (3) the strategy for blanket development, (4) the strategy for plasma exhaust solution development and (5) the requirements and state of readiness for next-step facility options. It was concluded that there is a need to continue and to focus the international discussion concerning the scientific and technical issues that determine the fusion roadmap, and it was suggested that an international activity be organized under appropriate auspices to foster international cooperation on these issues.

  2. Changes of the balancing between anode and cathode due to fatigue in commercial lithium-ion cells

    Science.gov (United States)

    Kleiner, Karin; Jakes, Peter; Scharner, Sebastian; Liebau, Verena; Ehrenberg, Helmut

    2016-06-01

    The electrode balancing defines the state of charge (SoC) of a lithium-ion cell and is a crucial point considering lifetime and safe operation. The electrode balancing varies during fatigue which results in changes of the individual electrode potentials for fixed (dis-)charge voltages of the full-cell. Therefore the materials are cycled closer or beyond their electrochemical (meta-)stability window. This leads to accelerated degradation reactions or even to safety problems. The origin of the changes in the cell balancing is the limited amount of mobile lithium, which decreases during cycling due to the loss of lithiated active material a), the reduction of accessible lattice sites in the active materials b) and the loss of active lithium outside the electrodes c). In most of the commercial cells a) and b) can be attributed to the cathode, c) occurs due to reactions on the anode surface. Changes in the electrode balancing of three differently fatigued 7 Ah lithium-ion cells are investigated by electrochemical cycling of full- and half-cells, assembled from cell components of the fatigued 7 Ah cells. Based on these results the observed performance drop is assigned to a), b) or c) mentioned above and the capacity losses are quantified.

  3. Space Heaters, Computers, Cell Phone Chargers: How Plugged In AreCommercial Buildings?

    Energy Technology Data Exchange (ETDEWEB)

    Sanchez, Marla; Webber, Carrie; Brown, Richard; Busch, John; Pinckard, Margaret; Roberson, Judy

    2007-02-28

    Evidenceof electric plug loads in commercial buildings isvisible everyday: space heaters, portable fans, and the IT technician'stwo monitors connected to one PC. The Energy Information Administrationestimates that office and miscellaneous equipment together will consume2.18 quads in 2006, nearly 50 percent of U.S. commercial electricity use.Although the importance of commercial plug loads is documented, its verynature (diverse product types, products not installed when buildinginitially constructed, and products often hidden in closets) makes itdifficult to accurately count and categorize the end use.We auditedsixteen buildings in three cities (San Francisco, Atlanta, Pittsburgh)including office, medical and education building types. We inventoriedthe number and types of office and miscellaneous electric equipment aswell as estimated total energy consumption due to these product types. Intotal, we audited approximately 4,000 units of office equipment and 6,000units of miscellaneous equipment and covered a diverse range of productsranging from electric pencil sharpeners with a unit energy consumption(UEC) of 1 kWh/yr to a kiln with a UEC of 7,000 kWh/yr. Our paperpresents a summary of the density and type of plug load equipment foundas well as the estimated total energy consumption of the equipment.Additionally, we present equipment trends observed and provide insightsto how policy makers can target energy efficiency for this growing enduse.

  4. Next Generation Integrated Power System: NGIPS Technology Development Roadmap

    Science.gov (United States)

    2007-11-30

    Technology Development Roadmap – Ser 05D/349 APPROVED FOR PUBLIC RELEASE 24 PCM (Inverter transformer co nverter) PCM (Inverter transformer converter) HVDC ...Technology Development Roadmap – Ser 05D/349 APPROVED FOR PUBLIC RELEASE 27 P C M -1 AMVAC HFAC HVDC or 1000 VDC via PCM-4 MVAC HFAC HVDC or 1000 VDC...require additional development. 3.9.2 PCM-2A A PCM-2A is an evolution of the PCM-2 of the IFTP system. For HVDC and HFAC systems, it converts

  5. The anatomy of a distributed motion planning roadmap

    KAUST Repository

    Jacobs, Sam Ade

    2014-09-01

    © 2014 IEEE. In this paper, we evaluate and compare the quality and structure of roadmaps constructed from parallelizing sampling-based motion planning algorithms against that of roadmaps constructed using sequential planner. Also, we make an argument and provide experimental results that show that motion planning problems involving heterogenous environments (common in most realistic and large-scale motion planning) is a natural fit for spatial subdivision-based parallel processing. Spatial subdivision-based parallel processing approach is suited for heterogeneous environments because it allows for local adaption in solving a global problem while taking advantage of scalability that is possible with parallel processing.

  6. The Roadmap to achieve EU goals on urban mobility

    DEFF Research Database (Denmark)

    Sørensen, Claus Hedegaard; Gudmundsson, Henrik; Schippl, Jens;

    2015-01-01

    Is it possible to change urban mobility in Europe to achieve ambitious sustainability goals? If so, who should dowhat by when? These questions are answered in a new Roadmap on urban mobility prepared as part of the European FP7 research project TRANSFORuM.......Is it possible to change urban mobility in Europe to achieve ambitious sustainability goals? If so, who should dowhat by when? These questions are answered in a new Roadmap on urban mobility prepared as part of the European FP7 research project TRANSFORuM....

  7. Roadmap on biosensing and photonics with advanced nano-optical methods

    Science.gov (United States)

    Di Fabrizio, Enzo; Schlücker, Sebastian; Wenger, Jérôme; Regmi, Raju; Rigneault, Hervé; Calafiore, Giuseppe; West, Melanie; Cabrini, Stefano; Fleischer, Monika; van Hulst, Niek F.; Garcia-Parajo, Maria F.; Pucci, Annemarie; Cojoc, Dan; Hauser, Charlotte A. E.; Ni, Ming

    2016-06-01

    This roadmap, through the contributions of ten groups worldwide, contains different techniques, methods and materials devoted to sensing in nanomedicine. Optics is used in different ways in the detection schemes. Raman, fluorescence and infrared spectroscopies, plasmonics, second harmonic generation and optical tweezers are all used in applications from single molecule detection (both in highly diluted and in highly concentrated solutions) to single cell manipulation. In general, each optical scheme, through device miniaturization and electromagnetic field localization, exploits an intrinsic optical enhancement mechanism in order to increase the sensitivity and selectivity of the device with respect to the complex molecular construct. The materials used for detection include nanoparticles and nanostructures fabricated with different 2D and 3D lithographic methods. It is shown that sensitivity to a single molecule is already accessible whether the system under study is a single cell or a multitude of cells in a molecular mixture. Throughout the roadmap there is an attempt to foresee and to suggest future directions in this interdisciplinary field.

  8. Roadmap on biosensing and photonics with advanced nano-optical methods

    KAUST Repository

    Di Fabrizio, Enzo M.

    2016-05-10

    This roadmap, through the contributions of ten groups worldwide, contains different techniques, methods and materials devoted to sensing in nanomedicine. Optics is used in different ways in the detection schemes. Raman, fluorescence and infrared spectroscopies, plasmonics, second harmonic generation and optical tweezers are all used in applications from single molecule detection (both in highly diluted and in highly concentrated solutions) to single cell manipulation. In general, each optical scheme, through device miniaturization and electromagnetic field localization, exploits an intrinsic optical enhancement mechanism in order to increase the sensitivity and selectivity of the device with respect to the complex molecular construct. The materials used for detection include nanoparticles and nanostructures fabricated with different 2D and 3D lithographic methods. It is shown that sensitivity to a single molecule is already accessible whether the system under study is a single cell or a multitude of cells in a molecular mixture. Throughout the roadmap there is an attempt to foresee and to suggest future directions in this interdisciplinary field. © 2016 IOP Publishing Ltd.

  9. The electrical behaviour of commercial solar cells under low concentration; Comportamiento electrico de celulas solares comerciales a baja concentracion

    Energy Technology Data Exchange (ETDEWEB)

    Martin, N.; Chenlo, F.

    2004-07-01

    The aim of this work is to analyse the electrical behaviour of commercial solar cells under low concentration. It is important to know the ideal concentration and temperature range that can be applied.. For that purpose we have tested the electrical characteristic of several solar cells of different technologies. The temperature during testing has been controlled (25, 40, 55 y 70 degree Celsius) and also the irradiance among 250 W/m (0,25X) and 2500 W/m2 (2,5X). The efficiency curves versus temperature show a maximum near 1000W/m and a decrease tendency caused by the serial resistance of the solar cell. The influence of temperature also function of the irradiance. (Author)

  10. Used fuel disposition research and development roadmap - FY10 status.

    Energy Technology Data Exchange (ETDEWEB)

    Nutt, W. M. (Nuclear Engineering Division)

    2010-10-01

    Since 1987 the U.S. has focused research and development activities relevant to the disposal of commercial used nuclear fuel and U.S. Department of Energy (DOE) owned spent nuclear fuel and high level waste on the proposed repository at Yucca Mountain, Nevada. At the same time, the U.S. successfully deployed a deep geologic disposal facility for defense-related transuranic waste in bedded salt at the Waste Isolation Pilot Plant. In 2009 the DOE established the Used Fuel Disposition Campaign (UFDC) within the Office of Nuclear Energy. The Mission of the UFDC is to identify alternatives and conduct scientific research and technology development to enable storage, transportation and disposal of used nuclear fuel and wastes generated by existing and future nuclear fuel cycles. The U.S. national laboratories have participated on these programs and has conducted research and development related to these issues to a limited extent. However, a comprehensive research and development (R&D) program investigating a variety of geologic media has not been a part of the U.S. waste management program since the mid 1980s. Such a comprehensive R&D program is being developed in the UFDC with a goal of meeting the UFDC Grand Challenge to provide a sound technical basis for absolute confidence in the safety and security of long-term storage, transportation, and disposal of used nuclear fuel and wastes from the nuclear energy enterprise. The DOE has decided to no longer pursue the development of a repository at Yucca Mountain, Nevada. Since a repository site will ultimately have to be selected, sited, characterized, designed, and licensed, other disposal options must now be considered. In addition to the unsaturated volcanic tuff evaluated at Yucca Mountain, several different geologic media are under investigation internationally and preliminary assessments indicate that disposal of used nuclear fuel and high level waste in these media is feasible. Considerable progress has been made in

  11. Program of scientific investigations and development of solid-oxide fuel cells (SOFC) in VNIITF. Proposals on scientific and technical collaboration and SOFC commercialization

    Energy Technology Data Exchange (ETDEWEB)

    Kleschev, Yu.N.; Chukharev, V.F.

    1996-04-01

    This paper describes proposals on scientific and technical collaborations pertaining to solid oxide fuel cell commercialization. Topics included for discussion are: materials research and manufacture; market estimation and cost; directions of collaboration; and project of proposals on joint enterprise creation.

  12. LiquidPower-1. Development and proof-of-concept of core methanol reformer for stationary and motive fuel cell systems and hydrogen refuelling stations. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Krogsgaard, J.; Mortensen, Henrik [H2 Logic A/S, Herning (Denmark); Skipper, T. [Dantherm Power A/S, Hobro (Denmark)

    2013-03-15

    LiquidPower-1 has developed laboratory test systems for methanol reforming and tested reformers from four different suppliers. This has contributed to determining the state-of-the-art level for methanol reforming and enabled an update of the LiquidPower R and D Roadmap onwards a commercialisation of the technology. The project has achieved the following results: 1) A detailed technical specification of methanol reformers for the fuel cell back-up power and hydrogen refueling station markets has been conducted; 2) Laboratory test systems for methanol reformers has been developed and established at Dantherm Power and H2 Logic; 3) Initial test of reformers from four suppliers has been conducted - with two suppliers being selected for continued tests; 4) Extensive laboratory tests conducted of reformers from two suppliers, with the aim to determine state-of-the-art for price, efficiency, capacity and lifetime. Several errors and break-downs were experienced during the test period, which revealed a need for further R and D to improve lifetime and stability; 5) The LiquidPower F and U Roadmap has been updated. Reformer TCO targets (Total Cost of Operation) for each of the markets have been calculated including updated targets for efficiency and cost. These targets also serve as the main ones to be pursued as part of the continued R and D roadmap execution. Compared to the previous edition of the Roadmap, the project has confirmed the viability of methanol reforming, but also revealed that stability and lifetime needs to be addressed and solved before commencing commercialization of the technology. If the Roadmap is successful a commercialization can commence beyond 2015. (Author)

  13. Clinical efficacy of Colgate 360 degrees and three commercially available toothbrushes on the removal of desquamated epithelial cells.

    Science.gov (United States)

    Williams, Malcolm I; Vazquez, Joe; Cummins, Diane

    2004-10-01

    A clinical study was done to evaluate the performance of four toothbrushes on the removal of desquamated epithelial cells after brushing according to the manufacturers' instructions for use. This randomized, crossover-design clinical study compared a new manual toothbrush (Colgate 360 degrees) to two commercially available manual toothbrushes (Oral-B CrossAction and Oral-B Indicator) and a commercially available battery-powered toothbrush (Crest SpinBrush PRO). Adult men and women subjects reported to the clinical facility after a 1-week "washout" period of brushing with a regular fluoride dentifrice and a soft-bristled toothbrush. Participants reported having refrained from oral hygiene procedures, eating, and drinking that morning. After providing a baseline rinse sample, subjects brushed their teeth for 1 minute with their assigned toothbrush and a commercially available fluoride toothpaste, then returned 30 minutes later to provide postuse rinse samples. Subjects refrained from dental hygiene, eating, and drinking during the 30-minute evaluation period. To provide the samples, subjects rinsed with 10 mL of sterile phosphate-buffered saline solution for 10 seconds. Each collected sample was centrifuged, resuspended, and run in a colorimetric assay to determine the level of desquamated epithelial cells found in the rinse as measured by the absorbance at 570 nm. Twenty adults completed the study. At baseline, the mean levels of desquamated epithelial cells for the 4 treatments were 0.70+/-0.27, 0.63+/-0.20, 0.69+/-0.30, and 0.62+/-0.31 for the Colgate 360 degrees, Oral-B Indicator, Crest SpinBrush PRO, and Oral-B CrossAction, respectively. Posttreatment, the mean levels of epithelial cells were 0.19, 0.38, 0.42, and 0.34, respectively. All of the treatments provided a statistically significant reduction compared to their respective baseline. In addition, the Colgate 360 degrees toothbrush was statistically significantly better than the other three toothbrushes in

  14. Plasma α-tocopherol content and its relationship with milk somatic cells count in Italian commercial herds.

    Directory of Open Access Journals (Sweden)

    Adriano Pilotto

    2015-07-01

    Full Text Available This work was aimed to investigate relationship between plasma vitamin E concentration and milk somatic cell count in healthy cows in commercial herds. 49 multiparous cows from two commercial dairy herds were monitored from the day of dry off until 90 DIM. BCS was assessed and blood samples were collected at dry off, day 0, 30, 60 and 90 postpartum. Plasma was analyzed for α-tocopherol content. Quantification of NEFA, BOHB, Zn and Se was performed in serum samples. Milk production and composition was obtained from routinely test-day of Italian milk producers association. Somatic Cell Score (SCS was calculated and included in the dataset. Analysis of data was performed using MIXED repeated and CORR procedures of SAS.We did not observe a correlation between plasmatic vitamin E and somatic cell score, and this can be explained by the low level of somatic cell score (averages 1.64 and 1.26. The lowest value of vitamin E was observed at parturition (1.64 µg/ml and 1.95 µg/ml. A significant (P<0.01 negative (-20% correlation was observed between NEFA serum content and α-tocopherol plasma concentration. Serum selenium content was positively correlated (+42%, P<0.0001 to zinc concentration. Grouping cows on the basis of their plasma α-tocopherol content higher or lower than 3 μg/mL at dry off, SCS at 30 and 60 DIM tended to be higher in lactating animals with lower content of α-tocopherol (1.12 vs. 1.72, P=0.18 at 30d; 0.92 vs. 1.72, P=0.07 at 60d. However, plasma α-tocopherol content at dry off could be usefully correlated with somatic cell count in fresh cows.

  15. A novel mechanistic modeling framework for analysis of electrode balancing and degradation modes in commercial lithium-ion cells

    Science.gov (United States)

    Schindler, Stefan; Danzer, Michael A.

    2017-03-01

    Aiming at a long-term stable and safe operation of rechargeable lithium-ion cells, elementary design aspects and degradation phenomena have to be considered depending on the specific application. Among the degrees of freedom in cell design, electrode balancing is of particular interest and has a distinct effect on useable capacity and voltage range. Concerning intrinsic degradation modes, understanding the underlying electrochemical processes and tracing the overall degradation history are the most crucial tasks. In this study, a model-based, minimal parameter framework for combined elucidation of electrode balancing and degradation pathways in commercial lithium-ion cells is introduced. The framework rests upon the simulation of full cell voltage profiles from the superposition of equivalent, artificially degraded half-cell profiles and allows to separate aging contributions from loss of available lithium and active materials in both electrodes. A physically meaningful coupling between thermodynamic and kinetic degradation modes based on the correlation between altered impedance features and loss of available lithium as well as loss of active material is proposed and validated by a low temperature degradation profile examined in one of our recent publications. The coupled framework is able to determine the electrode balancing within an error range of < 1% and the projected cell degradation is qualitatively and quantitatively in line with experimental observations.

  16. A National Roadmap for Vadose Zone Science and Technology

    Energy Technology Data Exchange (ETDEWEB)

    Kowall, Stephen Jacob

    2001-08-01

    This roadmap is a means of achieving, to the best of our current knowledge, a reasonable scientific understanding of how contaminants of all forms move in the vadose geological environments. This understanding is needed to reduce the present uncertainties in predicting contaminant movement, which in turn will reduce the uncertainties in remediation decisions.

  17. Local randomization in neighbor selection improves PRM roadmap quality

    KAUST Repository

    McMahon, Troy

    2012-10-01

    Probabilistic Roadmap Methods (PRMs) are one of the most used classes of motion planning methods. These sampling-based methods generate robot configurations (nodes) and then connect them to form a graph (roadmap) containing representative feasible pathways. A key step in PRM roadmap construction involves identifying a set of candidate neighbors for each node. Traditionally, these candidates are chosen to be the k-closest nodes based on a given distance metric. In this paper, we propose a new neighbor selection policy called LocalRand(k,K\\'), that first computes the K\\' closest nodes to a specified node and then selects k of those nodes at random. Intuitively, LocalRand attempts to benefit from random sampling while maintaining the higher levels of local planner success inherent to selecting more local neighbors. We provide a methodology for selecting the parameters k and K\\'. We perform an experimental comparison which shows that for both rigid and articulated robots, LocalRand results in roadmaps that are better connected than the traditional k-closest policy or a purely random neighbor selection policy. The cost required to achieve these results is shown to be comparable to k-closest. © 2012 IEEE.

  18. Reachability-based Analysis for Probabilistic Roadmap Planners

    NARCIS (Netherlands)

    Geraerts, R.J.; Overmars, M.H.

    2007-01-01

    In the last fifteen years, sampling-based planners like the Probabilistic Roadmap Method (PRM) have proved to be successful in solving complex motion planning problems. While theoretically, the complexity of the motion planning problem is exponential in the number of degrees of freedom, sampling-bas

  19. Science and Technology Roadmapping to Support Project Planning

    Energy Technology Data Exchange (ETDEWEB)

    Mc Carthy, Jeremiah Justin; Haley, Daniel Joseph; Dixon, Brent Wayne

    2001-07-01

    Disciplined science and technology roadmapping provides a framework to coordinate research and development activities with project objectives. This case-history paper describes initial project technology needs identification, assessment and R&D ranking activities supporting characterization of 781 waste tanks requiring a 'hazardous waste determination' or 'verification of empty' decision to meet an Idaho state Voluntary Consent Order.

  20. Synthesis-Spectroscopy Roadmap Problems: Discovering Organic Chemistry

    Science.gov (United States)

    Kurth, Laurie L.; Kurth, Mark J.

    2014-01-01

    Organic chemistry problems that interrelate and integrate synthesis with spectroscopy are presented. These synthesis-spectroscopy roadmap (SSR) problems uniquely engage second-year undergraduate organic chemistry students in the personal discovery of organic chemistry. SSR problems counter the memorize-or-bust strategy that many students tend to…

  1. European IST-programme roadmap for Optical Communications

    DEFF Research Database (Denmark)

    Ackaert, Ann; Demeester, Piet; Lagasse, Paul;

    2003-01-01

    On the basis of European IST project results in the field of photonics, the OPTIMIST thematic network has produced a roadmap for optical communications. This work is described in the present article which provides scenarios for the evolution of the optical network in the coming 10 years. Predicta...

  2. The pharmaceutical technology landscape: a new form of technology roadmapping

    NARCIS (Netherlands)

    Tierney, R.; Hermina, W.; Walsh, S.T.

    2013-01-01

    Practitioners are finding it increasingly difficult to develop effective roadmapping efforts for many new products and innovations. We argue that this difficulty stems from the fundamental differences between many of today's innovations and earlier ones. Many current innovations are: using technolog

  3. Web-Based Documentation System for Dynamic Roadmaps

    Science.gov (United States)

    Hassan, Sajid; Chishti, Ahsan; Elamvazuthi, Chandran

    2006-01-01

    Technology Roadmapping is a consensus-driven process to identify, evaluate, and select technology alternatives to satisfy the needs of a particular group of people. It serves as a high-level planning tool to support the development, implementation, and communication of technology development strategies and plans. The outcome of a technology…

  4. Comparative Study of Surface Temperature Behavior of Commercial Li-Ion Pouch Cells of Different Chemistries and Capacities by Infrared Thermography

    OpenAIRE

    2015-01-01

    The non-uniform surface temperature distribution of a battery cell results from complex reactions inside the cell and makes efficient thermal management a challenging task. This experimental work attempts to determine the evolution of surface temperature distribution of three pouch type commercial cells: Nickel Manganese Cobalt oxide (NMC)-based 20 Ah cell, Lithium Iron Phosphate (LFP) 14 Ah, and Lithium Titanate Oxide (LTO) 5 Ah battery cell by using contact thermistor and infrared (IR) the...

  5. Comparative Study of Surface Temperature Behavior of Commercial Li-Ion Pouch Cells of Different Chemistries and Capacities by Infrared Thermography

    OpenAIRE

    2015-01-01

    The non-uniform surface temperature distribution of a battery cell results from complex reactions inside the cell and makes efficient thermal management a challenging task. This experimental work attempts to determine the evolution of surface temperature distribution of three pouch type commercial cells: Nickel Manganese Cobalt oxide (NMC)-based 20 Ah cell, Lithium Iron Phosphate (LFP) 14 Ah, and Lithium Titanate Oxide (LTO) 5 Ah battery cell by using contact thermistor and infrared (IR) ther...

  6. Bay Area Transit Agencies Propel Fuel Cell Buses Toward Commercialization (Fact Sheet)

    Energy Technology Data Exchange (ETDEWEB)

    2010-07-01

    This fact sheet describes the Zero Emission Bay Area (ZEBA) demonstration of the next generation of fuel cells buses. Several transit agencies in the San Francisco Bay Area are participating in demonstrating the largest single fleet of fuel cell buses in the United States.

  7. Conversion of commercial si solar cells to keep their efficient performance at 15 suns

    Energy Technology Data Exchange (ETDEWEB)

    Coello, J. [Instituto Tecnologico y de Energias Renovables, Poligono Industrial de Granadilla, Tenerife (Spain); Castro, M.; Anton, I.; Sala, G. [Ciudad Univ., Madrid (Spain). Inst. de Energia Solar; Vazquez, M.A. [Isofoton, S.A., Poligono Industrial Santa Cruz, Malaga (Spain)

    2004-07-01

    The screen-printing method is an economical metallization technique used by most manufacturers of conventional silicon solar cells. This method limits the cells' use under concentrated light owing to high series resistance losses caused, among other reasons, by low metal density in the fingers. This paper describes increasing the finger metal density by electrolytic deposition. The electrolytic deposition of silver is an economical, controllable and readily commercializable deposition method to reduce the front and back metallization series resistance contributions. With an optimized grid design, compatible with 1 sun silicon cell technology, and later electrolytic silver deposition we have obtained cells that maintain their efficiency up to 15 suns. In addition, an analysis of the performance of these cells under uniform and non-uniform illumination were carried out on n{sup +}p and n{sup +}pn{sup +} structures. (author)

  8. Physicochemical characteristics and bronchial epithelial cell cytotoxicity of Folpan 80 WG® and Myco 500®, two commercial forms of folpet

    Directory of Open Access Journals (Sweden)

    Baldi Isabelle

    2007-09-01

    Full Text Available Abstract Background Pesticides, in particular folpet, have been found in rural and urban air in France in the past few years. Folpet is a contact fungicide and has been widely used for the past 50 years in vineyards in France. Slightly water-soluble and mostly present as particles in the environment, it has been measured at average concentration of 40.1 μg/m3 during its spraying, 0.16–1.2 μg/m3 in rural air and around 0.01 μg/m3 in urban air, potentially exposing both the workers and the general population. However, no study on its penetration by inhalation and on its respiratory toxicity has been published. The objective of this study was to determine the physicochemical characteristics of folpet particles (morphology, granulometry, stability in its commercial forms under their typical application conditions. Moreover, the cytotoxic effect of these particles and the generation of reactive oxygen species were assessed in vitro on respiratory cells. Results Granulometry of two commercial forms of folpet (Folpan 80WG® and Myco 500® under their typical application conditions showed that the majority of the particles (>75% had a size under 5 μm, and therefore could be inhaled by humans. These particles were relatively stable over time: more than 75% of folpet remained in the particle suspension after 30 days under the typical application conditions. The inhibitory concentration (IC50 on human bronchial epithelial cells (16HBE14o- was found to be between 2.89 and 5.11 μg/cm2 for folpet commercial products after 24 h of exposure. Folpet degradation products and vehicles of Folpan 80 WG® did not show any cytotoxicity at tested concentrations. At non-cytotoxic and subtoxic concentrations, Folpan 80 WG® was found to increase DCFH-DA fluorescence. Conclusion These results show that the particles of commercial forms of folpet are relatively stable over time. Particles could be easily inhaled by humans, could reach the conducting airways and are

  9. On the discharge capability and its limiting factors of commercial 18650 Li-ion cell at low temperatures

    Science.gov (United States)

    Fan, Jiang

    We here study the discharge capability of commercial 18650 cylindrical lithium-ion cells at low temperatures. The discharge capacity at -20 °C ranges from 67 to 88% of the rated capacity at 0.2 C rate, which is good. However, the cell discharge capacity varies substantially at -30 and -40 °C among the studied cells. It ranges from 2 to 70% of the rated capacity at -30 °C, and 0 to 30% at -40 °C at 0.2 C rate. The cell impedance at 1 kHz increases very little from room temperature down to -20 or -30 °C in general, which does not correlate with the cell discharge capability. However, the dc impedance is increased by a factor of about ten at -30 °C and about twenty at -40 °C from room temperature. The discharge capability at low temperature correlates well with the dc resistance at both room and low temperatures. The limiting factors in the discharge capability at low temperatures and the direction for the future improvement are discussed according to the cell discharge capability, the electrode geometric area, the cell impedance at 1 kHz, and the dc impedance at various temperatures. It appears that the ionic conductivity of the electrolyte and lithium solid diffusion in the electrode do not limit the cell discharge capability, while the lithium diffusion in the SEI layer on the positive surface may be the limiting factor. Cell discharge capability at low temperature does not correlate with cycle life at room temperature.

  10. CuInSe{sub 2} low-cost thin-film solar cells made from commercial elemental metallic nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Ungelenk, Jan; Haug, Veronika; Quintilla, Aina; Ahlswede, Erik [Zentrum fuer Sonnenenergie- und Wasserstoff-Forschung Baden-Wuerttemberg, Stuttgart (Germany)

    2010-04-15

    We present a method to prepare low-cost CuInSe{sub 2} (CIS) solar cells using commercially available low-grade elemental Cu and In nanoparticles without prior synthesis of CIS nanoparticle precursors. A simple non-vacuum ink deposition method is used where the nanoparticles are dispersed in alcohol and deposited onto a Mo/glass substrate in ambient atmosphere. Depending on the reduction and selenization steps, a compact CIS top layer comprising grains up to a few hundred nano- meters in size was observed to have formed using SEM and XRD. Complete solar cells were prepared by conventional methods, leading to a conversion efficiency well above 3%. (copyright 2010 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  11. A roadmap for photovoltaic-thermal panels. Combination of techniques offers many advantages; Een roadmap voor pv-thermische panelen. Combinatie van technieken biedt vele voordelen

    Energy Technology Data Exchange (ETDEWEB)

    Zondag, H.A.; Van Helden, W.G.J.; Bakker, M. [ECN Energie Gebouwde Omgeving en Netten, Petten (Netherlands)

    2006-10-15

    In PVT technology, heat is extracted from PV cells. In this way, a device is made that produces both electricity and heat. In the EU funded coordination action PV-Catapult, workshops on PVT were organised at the PVSEC 2004 Conference in Paris and the Eurosun 2004 conference in Freiburg, to obtain active participation of the PV and solar thermal communities. Currently, the results of the workshops are used in the drafting of a roadmap for the large scale introduction of PVT technology on the market. First results will be presented here. [Dutch] Zonnepanelen (oftewel pv-panelen) produceren elektriciteit uit zonlicht. In de volle zon kan de temperatuur van zonnepanelen flink oplopen. Gewone zonnepanelen maken van deze warmte geen gebruik, maar in PVT-modules (pv-thermische modules) wordt deze warmte benut voor de productie van warm water of warme lucht. Het resultaat is een apparaat dat zowel warmte als stroom produceert uit zonlicht.

  12. Higher Americium Oxidation State Research Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    Mincher, Bruce J. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Law, Jack D. [Idaho National Lab. (INL), Idaho Falls, ID (United States); Goff, George S. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Moyer, Bruce A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Burns, Jon D. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Lumetta, Gregg J. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Sinkov, Sergey I. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Shehee, Thomas C. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Hobbs, David T. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2015-12-18

    -solvent-extraction separations are also under investigation. The first would separate Am(VI) by co-crystallization with uranium and the other oxidizable actinides as their nitrate salts. This novel idea has been successful in lab scale testing, and merits further investigation. Similarly, success has been achieved in separations using inorganic or hybrid ion exchange materials to sorb the lanthanides and actinides, while allowing pentavalent americium to elute. This is the only technique currently investigating Am(V), despite the advantages of this oxidation state with regard to its higher stability. The ultimate destination for this roadmap is to develop an americium separation that can be applied under process conditions, preferably affording a co-separation of the actinyl (VI) ions. Toward that end, emphasis is given here to selection of a solvent extraction flowsheet for testing in the INL centrifugal contactor hot test bed during FY16. A solvent extraction process will be tested mainly because solvent extraction separations of Am(VI) are relatively mature and the test bed currently exists in a configuration to support them. Thus, a major goal of FY16 is to select the oxidant/ligand combination to run such a test using the contactors. The only ligands under consideration are DAAP and DEHBA. This is not to say that ion exchange and co-crystallization techniques are unimportant. They merit continued investigation, but are not mature enough for hot test bed testing at this time.

  13. A Roadmap for NEAMS Capability Transfer

    Energy Technology Data Exchange (ETDEWEB)

    Bernholdt, David E [ORNL

    2011-11-01

    The vision of the Nuclear Energy Advanced Modeling and Simulation (NEAMS) program is to bring truly predictive modeling and simulation (M&S) capabilities to the nuclear engineering community in order to enable a new approach to the design and analysis of nuclear energy systems. From its inception, the NEAMS program has always envisioned a broad user base for its software and scientific products, including researchers within the DOE complex, nuclear industry technology developers and vendors, and operators. However activities to date have focused almost exclusively on interactions with NEAMS sponsors, who are also near-term users of NEAMS technologies. The task of the NEAMS Capability Transfer (CT) program element for FY2011 is to develop a comprehensive plan to support the program's needs for user outreach and technology transfer. In order to obtain community input to this plan, a 'NEAMS Capability Transfer Roadmapping Workshop' was held 4-5 April 2011 in Chattanooga, TN, and is summarized in this report. The 30 workshop participants represented the NEAMS program, the DOE and industrial user communities, and several outside programs. The workshop included a series of presentations providing an overview of the NEAMS program and presentations on the user outreach and technology transfer experiences of (1) The Advanced Simulation and Computing (ASC) program, (2) The Standardized Computer Analysis for Licensing Evaluation (SCALE) project, and (3) The Consortium for Advanced Simulation of Light Water Reactors (CASL), followed by discussion sessions. Based on the workshop and other discussions throughout the year, we make a number of recommendations of key areas for the NEAMS program to develop the user outreach and technology transfer activities: (1) Engage not only DOE, but also industrial users sooner and more often; (2) Engage with the Nuclear Regulatory Commission to facilitate their understanding and acceptance of NEAMS approach to predictive M&S; (3

  14. Miniature ceramic-anvil high-pressure cell for magnetic measurements in a commercial superconducting quantum interference device magnetometer.

    Science.gov (United States)

    Tateiwa, Naoyuki; Haga, Yoshinori; Fisk, Zachary; Ōnuki, Yoshichika

    2011-05-01

    A miniature opposed-anvil high-pressure cell has been developed for magnetic measurement in a commercial superconducting quantum interference device magnetometer. Non-magnetic anvils made of composite ceramic material were used to generate high-pressure with a Cu-Be gasket. We have examined anvils with different culet sizes (1.8, 1.6, 1.4, 1.2, 1.0, 0.8, and 0.6 mm). The pressure generated at low temperature was determined by the pressure dependence of the superconducting transition of lead (Pb). The maximum pressure P(max) depends on the culet size of the anvil: the values of P(max) are 2.4 and 7.6 GPa for 1.8 and 0.6 mm culet anvils, respectively. We revealed that the composite ceramic anvil has potential to generate high-pressure above 5 GPa. The background magnetization of the Cu-Be gasket is generally two orders of magnitude smaller than the Ni-Cr-Al gasket for the indenter cell. The present cell can be used not only with ferromagnetic and superconducting materials with large magnetization but also with antiferromagnetic compounds with smaller magnetization. The production cost of the present pressure cell is about one tenth of that of a diamond anvil cell. The anvil alignment mechanism is not necessary in the present pressure cell because of the strong fracture toughness (6.5 MPa m(1∕2)) of the composite ceramic anvil. The simplified pressure cell is easy-to-use for researchers who are not familiar with high-pressure technology. Representative results on the magnetization of superconducting MgB(2) and antiferromagnet CePd(5)Al(2) are reported.

  15. Investigation of path dependence in commercial lithium-ion cells chosen for plug-in hybrid vehicle duty cycle protocols

    Science.gov (United States)

    Gering, Kevin L.; Sazhin, Sergiy V.; Jamison, David K.; Michelbacher, Christopher J.; Liaw, Bor Yann; Dubarry, Matthieu; Cugnet, Mikael

    There is a growing need to explore path dependence of aging processes in batteries developed for long-term usage, such as lithium-ion cells used in hybrid electric vehicle (HEV) or plug-in hybrid vehicle (PHEV) applications that may then be "retired" to be utilized in grid applications. To better understand the foremost influences on path dependence in the PHEV context, this work aims to bridge the gap between ideal laboratory test conditions and PHEV field conditions by isolating the predominant aging factors in PHEV service, which would include, for example, the nature and frequency of duty cycles, as well as the frequency and severity of thermal cycles. These factors are studied in controlled and repeatable laboratory conditions to facilitate mechanistic evaluation of aging processes. This work is a collaboration between Idaho National Laboratory (INL) and the Hawaii Natural Energy Institute (HNEI). Commercial lithium-ion cells of the Sanyo Y type (18650 configuration) are used in this work covering two initial independent studies of path dependence issues. The first study considers how the magnitude of power pulses and charging rates affect the aging rate, while the second seeks to answer whether thermal cycling has an accelerating effect on cell aging. While this work is in early stages of testing, initial data trends show that cell aging is indeed accelerated under conditions of high discharge pulse power, higher charge rates, and thermal cycling. Such information is useful in developing accurate predictive models for estimating end-of-life conditions.

  16. Light Water Reactor Sustainability (LWRS) Program – Non-Destructive Evaluation (NDE) R&D Roadmap for Determining Remaining Useful Life of Aging Cables in Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Simmons, K.L.; Ramuhali, P.; Brenchley, D.L.; Coble, J.B.; Hashemian, H.M.; Konnick, R.; Ray, S.

    2012-09-01

    Executive Summary [partial] The purpose of the non-destructive evaluation (NDE) R&D Roadmap for Cables is to support the Materials Aging and Degradation (MAaD) R&D pathway. A workshop was held to gather subject matter experts to develop the NDE R&D Roadmap for Cables. The focus of the workshop was to identify the technical gaps in detecting aging cables and predicting their remaining life expectancy. The workshop was held in Knoxville, Tennessee, on July 30, 2012, at Analysis and Measurement Services Corporation (AMS) headquarters. The workshop was attended by 30 experts in materials, electrical engineering, and NDE instrumentation development from the U.S. Nuclear Regulatory Commission (NRC), U.S. Department of Energy (DOE) National Laboratories (Oak Ridge National Laboratory, Pacific Northwest National Laboratory, Argonne National Laboratory, and Idaho National Engineering Laboratory), universities, commercial NDE service vendors and cable manufacturers, and the Electric Power Research Institute (EPRI).

  17. Light Water Reactor Sustainability (LWRS) Program – Non-Destructive Evaluation (NDE) R&D Roadmap for Determining Remaining Useful Life of Aging Cables in Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Simmons, Kevin L.; Ramuhalli, Pradeep; Brenchley, David L.; Coble, Jamie B.; Hashemian, Hash; Konnik, Robert; Ray, Sheila

    2012-09-14

    The purpose of the non-destructive evaluation (NDE) R&D Roadmap for Cables is to support the Materials Aging and Degradation (MAaD) R&D pathway. The focus of the workshop was to identify the technical gaps in detecting aging cables and predicting their remaining life expectancy. The workshop was held in Knoxville, Tennessee, on July 30, 2012, at Analysis and Measurement Services Corporation (AMS) headquarters. The workshop was attended by 30 experts in materials, electrical engineering, U.S. Nuclear Regulatory Commission (NRC), U.S. Department of Energy (DOE) National Laboratories (Oak Ridge National Laboratory, Pacific Northwest National Laboratory, Argonne National Laboratory, and Idaho National Engineering Laboratory), NDE instrumentation development, universities, commercial NDE services and cable manufacturers, and Electric Power Research Institute (EPRI). The motivation for the R&D roadmap comes from the need to address the aging management of in-containment cables at nuclear power plants (NPPs).

  18. The 2016 oxide electronic materials and oxide interfaces roadmap

    Science.gov (United States)

    Lorenz, M.; Ramachandra Rao, M. S.; Venkatesan, T.; Fortunato, E.; Barquinha, P.; Branquinho, R.; Salgueiro, D.; Martins, R.; Carlos, E.; Liu, A.; Shan, F. K.; Grundmann, M.; Boschker, H.; Mukherjee, J.; Priyadarshini, M.; DasGupta, N.; Rogers, D. J.; Teherani, F. H.; Sandana, E. V.; Bove, P.; Rietwyk, K.; Zaban, A.; Veziridis, A.; Weidenkaff, A.; Muralidhar, M.; Murakami, M.; Abel, S.; Fompeyrine, J.; Zuniga-Perez, J.; Ramesh, R.; Spaldin, N. A.; Ostanin, S.; Borisov, V.; Mertig, I.; Lazenka, V.; Srinivasan, G.; Prellier, W.; Uchida, M.; Kawasaki, M.; Pentcheva, R.; Gegenwart, P.; Miletto Granozio, F.; Fontcuberta, J.; Pryds, N.

    2016-11-01

    Oxide electronic materials provide a plethora of possible applications and offer ample opportunity for scientists to probe into some of the exciting and intriguing phenomena exhibited by oxide systems and oxide interfaces. In addition to the already diverse spectrum of properties, the nanoscale form of oxides provides a new dimension of hitherto unknown phenomena due to the increased surface-to-volume ratio. Oxide electronic materials are becoming increasingly important in a wide range of applications including transparent electronics, optoelectronics, magnetoelectronics, photonics, spintronics, thermoelectrics, piezoelectrics, power harvesting, hydrogen storage and environmental waste management. Synthesis and fabrication of these materials, as well as processing into particular device structures to suit a specific application is still a challenge. Further, characterization of these materials to understand the tunability of their properties and the novel properties that evolve due to their nanostructured nature is another facet of the challenge. The research related to the oxide electronic field is at an impressionable stage, and this has motivated us to contribute with a roadmap on ‘oxide electronic materials and oxide interfaces’. This roadmap envisages the potential applications of oxide materials in cutting edge technologies and focuses on the necessary advances required to implement these materials, including both conventional and novel techniques for the synthesis, characterization, processing and fabrication of nanostructured oxides and oxide-based devices. The contents of this roadmap will highlight the functional and correlated properties of oxides in bulk, nano, thin film, multilayer and heterostructure forms, as well as the theoretical considerations behind both present and future applications in many technologically important areas as pointed out by Venkatesan. The contributions in this roadmap span several thematic groups which are represented by

  19. Commercialization of bacterial cell factories for the sustainable production of polyhydroxyalkanoate thermoplastics: progress and prospects.

    Science.gov (United States)

    Kumar, Abhishek; Srivastava, Janmejai K; Mallick, Nirupama; Singh, Akhilesh K

    2015-01-01

    Ubiquitous conventional plastics, generally manufactured from finite, nonsustainable fossil fuels are non-biodegradable wonder entities but their ill effect on Mother Nature has subsequently raised major environmental concerns like their safe disposal, solid waste management and several potential hazards. Such concerns have fuelled initiatives for research globally towards development of sustainable and eco-friendly bioplastics. The new generation of plastics called 'bioplastics' are polymers of long chain of repeating monomer units that are classified as photodegradable, semi-biodegradable, chemically synthesized and polyhydroxyalkanoates (PHAs). The commonly emerged novel bioplastics are polyesters of hydroxyalkanoates (HAs) called PHAs, which are lipoidic storage materials found in the cytosol of vast and diverse forms of bacteria. Among 150 different PHAs known so far, poly- 3-hydroxybutyrate is the most common and comprehensively characterized PHA. Interestingly, PHAs are only completely biodegradable plastics with material properties comparable to conventional plastics that can be achieved by regulating the co-monomers incorporation into PHAs backbone. PHA bioplastics are exploited in the form of user-friendly goods viz. films, absorbable sutures, bone plates, drug carriers, etc. Besides advantages, such useful entity(s) has major shortcomings as well like high production cost compared to conventional plastics. Precisely, in PHAs production, about fifty percent of the overall price is due to the carbon substrates. Consequently, exploring novel cost-effective substrates is a major compulsion for successful commercialization of this bioplastic, which is anticipated to reduce the cost of production as a result of advancing and intensifying research work. This review presents an insight and patent developments in the field of PHAs bioplastics.

  20. Development of an Online Toolkit for Measuring Commercial Building Energy Efficiency Performance -- Scoping Study

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Na

    2013-03-13

    This study analyzes the market needs for building performance evaluation tools. It identifies the existing gaps and provides a roadmap for the U.S. Department of Energy (DOE) to develop a toolkit with which to optimize energy performance of a commercial building over its life cycle.

  1. Effects of the Commercial Flame Retardant Mixture DE-71 on Cytokine Production by Human Immune Cells

    DEFF Research Database (Denmark)

    Mynster Kronborg, Thit; Frohnert Hansen, Juliana; Nielsen, Claus Henrik

    2016-01-01

    INTRODUCTION: Although production of polybrominated diphenyl ethers (PBDEs) is now banned, release from existing products will continue for many years. The PBDEs are assumed to be neurotoxic and toxic to endocrine organs at low concentrations. Their effect on the immune system has not been...... investigated thoroughly. We aimed to investigate the influence of DE-71 on cytokine production by peripheral blood mononuclear cells (PBMCs) stimulated with Escherichia Coli lipopolysaccharide (LPS) or phytohaemagglutinin-L (PHA-L). MATERIAL AND METHODS: PBMCs isolated from healthy donors were pre......-incubated with DE-71 at various concentrations and subsequently incubated with the monocyte stimulator LPS, or the T-cell activator PHA-L. Interferon (IFN)-γ, interleukin (IL)-1β, IL-2, IL-4, IL-6, IL-8, IL-10, tumor necrosis factor (TNF)-α, IL-17A, and IL-17F were quantified in the supernatants by Luminex kits...

  2. Identify capacity fading mechanism in a commercial LiFePO 4 cell

    Science.gov (United States)

    Dubarry, Matthieu; Liaw, Bor Yann

    The capacity fading of an 18650 LiFePO 4-based lithium ion cell was studied using the dynamic stress test (DST) schedule in a cycle life evaluation. Intermittent reference performance tests were conducted to quantify capacity loss and peak power capability degradation with cycle number to the end-of-life. An incremental capacity analysis was applied to identify various contributions to capacity loss, whereas the open circuit voltage measurements were utilized to trace the correct state of charge as the cell degrades in order to accurately correlate the capacity degradation with SOC. Our non-invasive, in situ analyses are in general consistent with current understanding of the degradation mechanism in this chemistry derived from post-mortem analysis. Loss of lithium inventory is the main cause of capacity degradation, in addition to the loss of active materials. The degree of under-discharge and under-charge is quite minimal under the test protocol.

  3. Capacity and power fading mechanism identification from a commercial cell evaluation

    Science.gov (United States)

    Dubarry, Matthieu; Svoboda, Vojtech; Hwu, Ruey; Liaw, Bor Yann

    An 18650 lithium ion cell was evaluated using dynamic stress test (DST) protocol for cycle life study. Reference performance tests were applied every 60 DST cycles to quantify capacity fade and peak power capability (PPC) degradation with cycles to the end of life. A quantitative incremental capacity analysis (ICA) was applied to identify extrinsic and intrinsic contributions to capacity fading, whereas the open circuit voltage (OCV) measurements were utilized to determine the correct state of charge (SOC) in order to accurately correlate the capacity fade with SOC. The analysis also helps us identify that cell polarization resistance change in the cycles is the primary culprit that bifurcates to both extrinsic and intrinsic origins in capacity fade and PPC degradation. This analysis allows us to develop better understanding in predicting battery performance and life in the rechargeable lithium batteries.

  4. Commercial applicability of cell microancapsulation: a review of intellectual property rights.

    Science.gov (United States)

    Meier, Stephan M

    2010-01-01

    Maturity and applicability of a distinct field of science can be estimated, using a review of current filing statistics of patent applications. Therefore, hereby a search based on international classifications has been directed to the world intellectual property organization (WIPO) to determine the amount and content of patent applications related to the field of cell microencapsulation. The search was evaluated with regard to the distinct indications envisaged and an evaluation of possible technology gaps for fostering further progress was conducted.

  5. Survey on commercial use of fuel cells; Nenryo denchi ni kansuru jitsuyoka no tame no chosa

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-03-01

    The basic survey was carried out for the future approach to R & D of fuel cells. Phosphoric acid fuel cell (PAFC) is in the stage of demonstration research and field test supported by subsidy after the end of Sunshine project. Its reliability and durability problems are being solved, and its cost reduction is only one problem for practical use. Distributed systems or on-site systems will be used utilizing its excellent environmental characteristics. Molten carbonate fuel cell (MCFC), solid oxide one (SOFC) and polymer electrolyte one (PEFC) under development were thus surveyed. The following are surveyed: (1) Contribution to a human society such as improvement of energy demand/supply structure and environmental protection, (2) Technological items such as outlook for R & D, validity of developmental issues, comparison between various R & D and significance in industrial promotion, (3) Economic items such as profitability and feasible period, and (4) Social items such as sociability, compatibility to needs, possibility of locations, international meaning, market scale and promotion scenario. 90 refs., 67 figs., 96 tabs.

  6. Cytogenetic effects of three commercially formulated pesticides on somatic and germ cells of Allium cepa.

    Science.gov (United States)

    Kuchy, Aashiq H; Wani, Aijaz A; Kamili, Azra N

    2016-04-01

    Cytological effects of Endosri-ES (endosulfan), Nuvan-NU (dichlorvos), and Kvistin-KS (carbendazim) were evaluated on mitotic and meiotic cells of Allium cepa. Test concentrations were chosen by calculating EC50 values of formulated ES, NU, and KS, which turned to be 60, 200, and 500 ppm (parts per million), respectively. Cytological studies were undertaken on root meristem cells of A. cepa using EC50, 1/2 × EC50, and 2 × EC50 of these pesticides for 24 and 48 h. Similarly, a meiotic study was conducted by applying the pesticides at the aforesaid concentrations from seedling to bud stage. A set of onion bulbs exposed to tap water was run parallel for negative control and maleic hydrazide (112.09 ppm) as positive control. During the study period, mitotic index (MI) decreased at all the pesticide concentrations compared to the negative control. Among various chromosomal aberrations, chromatin bridges, breaks, stickiness, laggard, vagrant chromosomes, fragments, C-mitosis, multipolarity, ring chromosome as well as micronuclei were observed in mitotic preparations. In contrast, meiotic aberrations revealed comparatively less frequency of chromosomal aberrations and the most frequent were lagging chromosome, stray bivalents, secondary association, chromatin bridge, disturbed anaphase, and stickiness. Comparative analysis of the pesticides showed that NU was highly toxic to plant cells than KS, while as ES showed intermediate effects between the two. Further, our study revealed that all the three pesticides produce genotoxic effects which can cause health risks to the human populations. Graphical Abstract ᅟ.

  7. Scenarios and strategies leading to the worldwide commercialization of hydrogen and fuel cells

    Energy Technology Data Exchange (ETDEWEB)

    Evers, A.A. [FAIR-PR, Starnberg (Germany)

    2007-07-01

    The global demand for fuel for mobile, stationary and transport applications has significantly increased the need for hydrogen. Hydrogen can be produced from fossil fuels, from gasification of coal, steam reforming of natural gas, and from nuclear energy. However, hydrogen must be produced directly from renewable energies such as wind, photovoltaic, and biomass in order to have a carbon dioxide (CO{sub 2}) emission free energy carrier without polluted nuclear waste. This conference lecture demonstrated how past trends and implementations of new technologies impact daily life and discussed how these models could be applied to the future implementation of hydrogen and fuel cells. The presentation examined various products and markets from around the world. In addition, it compared how strong consumer influence has played a role in the success of the worldwide implementation of inventions over the centuries, with an outlook to the future. It discussed the energy balance that is uneconomical due to high flaring and transmission losses. Examples from Germany were presented along with an examination of marketplaces for the use of hydrogen and fuel cells applications and services in China and India. It was concluded that public demand will play an important role in creating demand for hydrogen and fuel cell technologies. 9 figs.

  8. NASA Space Technology Draft Roadmap Area 13: Ground and Launch Systems Processing

    Science.gov (United States)

    Clements, Greg

    2011-01-01

    This slide presentation reviews the technology development roadmap for the area of ground and launch systems processing. The scope of this technology area includes: (1) Assembly, integration, and processing of the launch vehicle, spacecraft, and payload hardware (2) Supply chain management (3) Transportation of hardware to the launch site (4) Transportation to and operations at the launch pad (5) Launch processing infrastructure and its ability to support future operations (6) Range, personnel, and facility safety capabilities (7) Launch and landing weather (8) Environmental impact mitigations for ground and launch operations (9) Launch control center operations and infrastructure (10) Mission integration and planning (11) Mission training for both ground and flight crew personnel (12) Mission control center operations and infrastructure (13) Telemetry and command processing and archiving (14) Recovery operations for flight crews, flight hardware, and returned samples. This technology roadmap also identifies ground, launch and mission technologies that will: (1) Dramatically transform future space operations, with significant improvement in life-cycle costs (2) Improve the quality of life on earth, while exploring in co-existence with the environment (3) Increase reliability and mission availability using low/zero maintenance materials and systems, comprehensive capabilities to ascertain and forecast system health/configuration, data integration, and the use of advanced/expert software systems (4) Enhance methods to assess safety and mission risk posture, which would allow for timely and better decision making. Several key technologies are identified, with a couple of slides devoted to one of these technologies (i.e., corrosion detection and prevention). Development of these technologies can enhance life on earth and have a major impact on how we can access space, eventually making routine commercial space access and improve building and manufacturing, and weather

  9. Note: Improved sensitivity of magnetic measurements under high pressure in miniature ceramic anvil cell for a commercial SQUID magnetometer.

    Science.gov (United States)

    Tateiwa, Naoyuki; Haga, Yoshinori; Matsuda, Tatsuma D; Fisk, Zachary; Ikeda, Shugo; Kobayashi, Hisao

    2013-04-01

    Two modifications have been made to a miniature ceramic anvil high pressure cell (mCAC) designed for magnetic measurements at pressures up to 12.6 GPa in a commercial superconducting quantum interference (SQUID) magnetometer [N. Tateiwa et al., Rev. Sci. Instrum. 82, 053906 (2011); ibid. 83, 053906 (2012)]. Replacing the Cu-Be piston in the former mCAC with a composite piston composed of the Cu-Be and ceramic cylinders reduces the background magnetization significantly smaller at low temperatures, enabling more precise magnetic measurements at low temperatures. A second modification to the mCAC is the utilization of a ceramic anvil with a hollow in the center of the culet surface. High pressures up to 5 GPa were generated with the "cupped ceramic anvil" with the culet size of 1.0 mm.

  10. Analog front-end cell designed in a commercial 025 mu m process for the ATLAS pixel detector at LHC

    CERN Document Server

    Blanquart, L; Comes, G; Denes, P; Einsweiler, Kevin F; Fischer, P; Mandelli, E; Meddeler, G; Peric, I; Richardson, J

    2002-01-01

    A new analog pixel front-end cell has been developed for the ATLAS detector at the future Large Hadron Collider (LHC) at the European Laboratory for Particle Physics (CERN). This analog cell has been submitted in two commercial 0.25 mu m CMOS processes (in an analog test chip format), using special layout techniques for radiation hardness purposes. It is composed of two cascaded amplifiers followed by a fast discriminator featuring a detection threshold within the range of 1000 to 10000 electrons. The first preamplifier has the principal role of providing a large bandwidth, low input impedance, and fast rise time in order to enhance the time-walk and crosstalk performance, whereas the second fully differential amplifier is aimed at delivering a sufficiently high-voltage gain for optimum comparison. A new do feedback concept renders the cell tolerant of sensor leakage current up to 300 nA and provides monitoring of this current. Two 5-bit digital-to-analog converters tolerant to single- event upset have been i...

  11. Technology Roadmaps: Carbon Capture and Storage in Industrial Applications

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    A new technology roadmap on Carbon Capture and Storage in Industrial Applications, released today in Beijing, shows that carbon capture and storage (CCS) has the potential to reduce CO2 emissions from industrial applications by 4 gigatonnes in 2050. Such an amount is equal to roughly one-tenth of the total emission cuts needed from the energy sector by the middle of the century. This requires a rapid deployment of CCS technologies in various industrial sectors, and across both OECD and non-OECD countries. The roadmap, a joint report from the International Energy Agency (IEA) and the United Nations Industrial Development Organization (UNIDO), says that over 1800 industrial-scale projects are required over the next 40 years.

  12. Implementing the Research Data Management Policy: University of Edinburgh Roadmap

    Directory of Open Access Journals (Sweden)

    Robin Rice

    2013-11-01

    Full Text Available This paper discusses work to implement the University of Edinburgh Research Data Management (RDM policy by developing the services needed to support researchers and fulfil obligations within a changing national and international setting. This is framed by an evolving Research Data Management Roadmap and includes a governance model that ensures cooperation amongst Information Services (IS managers and oversight by an academic-led steering group. IS has taken requirements from research groups and IT professionals, and at the request of the steering group has conducted pilot work involving volunteer research units within the three colleges to develop functionality and presentation for the key services. The first pilots cover three key services: the data store, a customisation of the Digital Curation Centre’s DMPonline tool, and the data repository. The paper will report on the plans, achievements and challenges encountered while we attempt to bring the University of Edinburgh RDM Roadmap to fruition.

  13. Mission Assurance Modeling and Simulation: A Cyber Security Roadmap

    Science.gov (United States)

    Gendron, Gerald; Roberts, David; Poole, Donold; Aquino, Anna

    2012-01-01

    This paper proposes a cyber security modeling and simulation roadmap to enhance mission assurance governance and establish risk reduction processes within constrained budgets. The term mission assurance stems from risk management work by Carnegie Mellon's Software Engineering Institute in the late 19905. By 2010, the Defense Information Systems Agency revised its cyber strategy and established the Program Executive Officer-Mission Assurance. This highlights a shift from simply protecting data to balancing risk and begins a necessary dialogue to establish a cyber security roadmap. The Military Operations Research Society has recommended a cyber community of practice, recognizing there are too few professionals having both cyber and analytic experience. The authors characterize the limited body of knowledge in this symbiotic relationship. This paper identifies operational and research requirements for mission assurance M&S supporting defense and homeland security. M&S techniques are needed for enterprise oversight of cyber investments, test and evaluation, policy, training, and analysis.

  14. A Roadmap for Strategic Development of Geothermal Exploration Technologies

    Energy Technology Data Exchange (ETDEWEB)

    Phillips, Benjamin R. [SRA International Inc. and Geothermal Technologies Office, Washington, DC (United States); Ziagos, John [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Thorsteinsson, Hildigunnur [Geothermal Technologies Office, Washington, DC (United States); Hass, Eric [Geothermal Technologies Office, Golden, CO (United States)

    2013-02-13

    Characterizing productive geothermal systems is challenging yet critical to identify and develop an estimated 30 gigawatts electric (GWe) of undiscovered hydrothermal resources in the western U.S. This paper, undertaken by the U.S. Department of Energy’s Geothermal Technologies Office (GTO), summarizes needs and technical pathways that target the key geothermal signatures of temperature, permeability, and fluid content, and develops the time evolution of these pathways, tying in past and current GTO exploration Research and Development (R&D) projects. Beginning on a five-year timescale and projecting out to 2030, the paper assesses technologies that could accelerate the confirmation of 30 GWe. The resulting structure forms the basis for a Geothermal Exploration Technologies Roadmap, a strategic development plan to help guide GTO R&D investments that will lower the risk and cost of geothermal prospect identification. This roadmap is currently open for public comment. Send your comments to geothermal@ee.doe.gov.

  15. Technology Development Roadmaps - a Systematic Approach to Maturing Needed Technologies

    Energy Technology Data Exchange (ETDEWEB)

    John W. Colllins; Layne Pincock

    2010-07-01

    Abstract. Planning and decision making represent important challenges for all projects. This paper presents the steps needed to assess technical readiness and determine the path forward to mature the technologies required for the Next Generation Nuclear Plant. A Technology Readiness Assessment is used to evaluate the required systems, subsystems, and components (SSC) comprising the desired plant architecture and assess the SSCs against established Technology Readiness Levels (TRLs). A validated TRL baseline is then established for the proposed physical design. Technology Development Roadmaps are generated to define the path forward and focus project research and development and engineering tasks on advancing the technologies to increasing levels of maturity. Tasks include modeling, testing, bench-scale demonstrations, pilot-scale demonstrations, and fully integrated prototype demonstrations. The roadmaps identify precise project objectives and requirements; create a consensus vision of project needs; provide a structured, defensible, decision-based project plan; and, minimize project costs and schedules.

  16. Astroparticle physics in Europe gets a new roadmap

    CERN Multimedia

    Fabio Capello

    2011-01-01

    After publishing its first strategy plan in 2008, the AStroParticle European Research Area (ASPERA) – a network of European national funding agencies responsible for astroparticle physics – has just published an update. The new document provides an overview of the activities of the astroparticle physics community, makes recommendations for future projects and emphasizes the role of networking and sharing among the funding agencies.   The new strategies for Astroparticle Physics (ApP) – the research field at the intersection of astrophysics, particle physics and cosmology – were discussed at a meeting held in Paris on 21 and 22 November, when a new roadmap was presented to the community. “An update of the strategic plan published in 2008 was needed because of the significant progress made in recent years,” explains Arnaud Marsollier, ASPERA press officer. “In this new roadmap, ASPERA gives an updated overview of ApP Projects ...

  17. Chemical Industry R&D Roadmap for Nanomaterials By Design. From Fundamentals to Function

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2003-12-01

    Vision2020 agreed to join NNI and the U.S. Department of Energy's Office of Energy Efficiency and Renewable Energy (DOE/EERE) in sponsoring the "Nanomaterials and the Chemical Industry Roadmap Workshop" on September 30-October 2, 2002. This roadmap, Chemical Industry R&D Roadmap for Nanomaterials By Design: From Fundamentals to Function, is based on the scientific priorities expressed by workshop participants from the chemical industry, universities, and government laboratories.

  18. Technology roadmapping: The integration of strategic and technology planning for competitiveness

    Energy Technology Data Exchange (ETDEWEB)

    Bray, O.H.; Garcia, M.L.

    1997-04-01

    Technology roadmapping is a form of technology planning that can help organizations deal with an increasingly competitive environment. As a DOE laboratory with R&D as a major product, Sandia must do effective technology planning to identify and develop technologies required to meet its mission. Once technology enhancements or new technologies are identified, they may be developed internally or collaboratively with external partners. For either approach, technology roadmapping is an effective tool for technology planning and coordination, which fits within a broader set of planning activities. Potential benefits of roadmapping include identifying critical technologies and gaps, coordination of research activities, and improved marketing information. Roadmapping is particularly useful when investment decisions are not straightforward and for coordinating the development of multiple technologies, especially across multiple projects. This paper formalizes and documents the technology roadmapping process. It describes the process and shows how it fits within an overall strategic and technology planning process. The technology roadmapping process consists of three phases: preliminary activity, development of the roadmap, and followup activity. Preliminary activity includes: satisfy essential conditions, provide leadership/sponsorship, and define the scope and boundaries for the roadmap. Development of the technology roadmap includes: (1) Identify the {open_quotes}product{close_quotes} that will be the focus of the roadmap. (2) Identify the critical system requirements and their targets. (3) Specify the major technology areas. (4) Specify the technology drivers and their targets. (5) Identify technology alternatives and their time lines. (6) Recommend the technology alternatives that should be pursued. (7) Create the technology roadmap report. Follow-up activity includes: (1) Critique and validate the roadmap. (2) Develop an implementation plan. (3) Review and update.

  19. Commercialization of New Lattice-Matched Multi-Junction Solar Cells Based on Dilute Nitrides: July 8, 2010 - March 7, 2012

    Energy Technology Data Exchange (ETDEWEB)

    Herb, J.

    2012-04-01

    Final Technical Progress Report for PV Incubator subcontract NAT-0-99013-03. The overall objective of this Incubator subcontract was to complete the work necessary to make commercial ready solar cells using the dilute nitride technology. The specific objectives of this program were aimed at completing the development of a triple-junction solar cell that incorporates a GaInNAs {approx}1eV subcell to the point of commercial readiness, and determining the cell reliability and, if necessary, identifying and eliminating process or material related issues that lead to early-life cell failures. There were three major objectives for Phase 1, each of which focuses on a key element of the solar cell that determines its performance in a commercial CPV system. One objective was to optimize the quality and performance of the key individual components making up the solar cell structure and then to optimize the integration of these components into a complete triple-junction cell. A second objective was to design and test anti-reflective coating that maximizes the light coupled into a 3J cell with a {approx}1 eV bottom cell bandgap. The third objective was to develop Highly Accelerated Life Tests (HALT) protocols and tools for identifying and correcting potential reliability problems. The Phase 2 objectives were a continuation of the work begun in Phase 1 but aimed at optimizing cell performance for commercial requirements. Phase 2 had four primary objectives: (1) develop a glass-matched anti-reflective coating (ARC) and optimize the cell/ARC to give good performance at 60C operating temperature, (2) optimize the cell for good operation at 60C and high concentration, and (3) complete the light biased HALT system and use it to determine what, if any, failures are observed, and (4) determine the reliability limits of the optimized cell.

  20. Used fuel disposition research and development roadmap - FY10 status.

    Energy Technology Data Exchange (ETDEWEB)

    Nutt, W. M. (Nuclear Engineering Division)

    2010-10-01

    Since 1987 the U.S. has focused research and development activities relevant to the disposal of commercial used nuclear fuel and U.S. Department of Energy (DOE) owned spent nuclear fuel and high level waste on the proposed repository at Yucca Mountain, Nevada. At the same time, the U.S. successfully deployed a deep geologic disposal facility for defense-related transuranic waste in bedded salt at the Waste Isolation Pilot Plant. In 2009 the DOE established the Used Fuel Disposition Campaign (UFDC) within the Office of Nuclear Energy. The Mission of the UFDC is to identify alternatives and conduct scientific research and technology development to enable storage, transportation and disposal of used nuclear fuel and wastes generated by existing and future nuclear fuel cycles. The U.S. national laboratories have participated on these programs and has conducted research and development related to these issues to a limited extent. However, a comprehensive research and development (R&D) program investigating a variety of geologic media has not been a part of the U.S. waste management program since the mid 1980s. Such a comprehensive R&D program is being developed in the UFDC with a goal of meeting the UFDC Grand Challenge to provide a sound technical basis for absolute confidence in the safety and security of long-term storage, transportation, and disposal of used nuclear fuel and wastes from the nuclear energy enterprise. The DOE has decided to no longer pursue the development of a repository at Yucca Mountain, Nevada. Since a repository site will ultimately have to be selected, sited, characterized, designed, and licensed, other disposal options must now be considered. In addition to the unsaturated volcanic tuff evaluated at Yucca Mountain, several different geologic media are under investigation internationally and preliminary assessments indicate that disposal of used nuclear fuel and high level waste in these media is feasible. Considerable progress has been made in

  1. Access to the Sea: A Roadmap for Expedition Planning

    Science.gov (United States)

    DeSilva, A. M.; Girguis, P. R.

    2014-12-01

    The planning process for expeditionary oceanography often spans many years and involves multiple steps, starting from the initial proposal, to logistics planning, cruise execution, post-cruise and scientific reporting. Each year the University-National Oceanographic Laboratory System (UNOLS) Fleet supports a broad spectrum of research operations and their associated logistics support requirements. Operations can vary from single Principle Investigator (PI) cruises to multi-investigators field programs with multi-disciplinary research objectives in locations all over the world. Over the past decade, the process for access to the sea has evolved and continues to be refined through the critical feedback of scientists, marine technicians, and ship operators. Under UNOLS guidance, key guidelines have been identified for all phases of cruise planning; from pre-award to post-expedition to help ensure that the research objectives of programs can be met and that optimal use of our Nation's oceanographic facilities is maintained. An expeditionary roadmap has been created that captures the major milestones essential to executing a research cruise. The roadmap has been introduced during early career scientist workshops and also during the Chief Scientist Training Cruise programs of recent years. It is a useful planning tool not only for early career scientists and new ship users, but also for experienced sea-going scientists. The roadmap will soon be available as a resource tool on the new UNOLS website. This poster will feature the roadmap for expeditionary planning and offer key information about requirements and tips for a successful, safe, research cruise experience. In addition, existing and new requirements associated with custom clearances, export licensing requirements and additional planning considerations also needed when the research requires special facilities such as aircraft or deep submergence vehicles will be discussed.

  2. Nanotechnology for the Forest Products Industry Vision and Technology Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    Atalla, Rajai [USDA Forest Service, Washington, DC (United States); Beecher, James [USDA Forest Service, Washington, DC (United States); Caron, Robert [Technical Association of the Pulp and Paper Industry, Peachtree Corners, GA (United States); Catchmark, Jeffrey [Pennsylvania State Univ., State College, PA (United States); Deng, Yulin [Georgia Inst. of Technology, Atlanta, GA (United States); Glasser, Wolfgang [Virginia Polytechnic Inst. and State Univ. (Virginia Tech), Blacksburg, VA (United States); Gray, Derek [McGill Univ., Montreal, QC (Canada); Haigler, Candace [North Carolina State Univ., Raleigh, NC (United States); Jones, Philip [Imerys, Paris (France); Joyce, Margaret [Western Michigan Univ., Kalamazoo MI (United States); Kohlman, Jane [USDA Forest Service, Washington, DC (United States); Koukoulas, Alexander [Technical Association of the Pulp and Paper Industry, Peachtree Corners, GA (United States); Lancaster, Peter [Weyerhaeuser Company, Longview, WA (United States); Perine, Lori [American Forest and Paper Association, Washington, DC (United States); Rodriguez, Augusto [Georgia-Pacific Corporation, Atlanta, GA (United States); Ragauskas, Arthur [Georgia Inst. of Technology, Atlanta, GA (United States); Wegner, Theodore [USDA Forest Service, Washington, DC (United States); Zhu, Junyong [USDA Forest Service, Washington, DC (United States)

    2005-03-01

    A roadmap for Nanotechnology in the Forest Products Industries has been developed under the umbrella of the Agenda 2020 program overseen by the CTO committee. It is expected that the use of new analytical techniques and methodologies will allow us to understand the complex nature of wood based materials and allow the dramatically enhanced use of the major strategic asset the US has in renewable, recyclable resources based on its well managed Forests.

  3. Codecharts roadmaps and blueprints for object-oriented programs

    CERN Document Server

    Eden, Amnon H

    2011-01-01

    NEW LANGUAGE VISUALIZES PROGRAM ABSTRACTIONS CLEARLY AND PRECISELY Popular software modelling notations visualize implementation minutiae but fail to scale, to capture design abstractions, and to deliver effective tool support. Tailored to overcome these limitations, Codecharts can elegantly model roadmaps and blueprints for Java, C++, and C# programs of any size clearly, precisely, and at any level of abstraction. More practically, significant productivity gains for programmers using tools supporting Codecharts have been demonstrated in controlled experiments. Hundreds of figures a

  4. Technology Roadmap for Energy Reduction in Automotive Manufacturing

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2008-09-01

    U.S. Department of Energy’s (DOE) Industrial Technologies Program (ITP), in collaboration with the United States Council for Automotive Research LLC (USCAR), hosted a technology roadmap workshop in Troy, Michigan in May 2008. The purpose of the workshop was to explore opportunities for energy reduction, discuss the challenges and barriers that might need to be overcome, and identify priorities for future R&D. The results of the workshop are presented in this report.

  5. Effects of the Commercial Flame Retardant Mixture DE-71 on Cytokine Production by Human Immune Cells.

    Directory of Open Access Journals (Sweden)

    Thit Mynster Kronborg

    Full Text Available Although production of polybrominated diphenyl ethers (PBDEs is now banned, release from existing products will continue for many years. The PBDEs are assumed to be neurotoxic and toxic to endocrine organs at low concentrations. Their effect on the immune system has not been investigated thoroughly. We aimed to investigate the influence of DE-71 on cytokine production by peripheral blood mononuclear cells (PBMCs stimulated with Escherichia Coli lipopolysaccharide (LPS or phytohaemagglutinin-L (PHA-L.PBMCs isolated from healthy donors were pre-incubated with DE-71 at various concentrations and subsequently incubated with the monocyte stimulator LPS, or the T-cell activator PHA-L. Interferon (IFN-γ, interleukin (IL-1β, IL-2, IL-4, IL-6, IL-8, IL-10, tumor necrosis factor (TNF-α, IL-17A, and IL-17F were quantified in the supernatants by Luminex kits.At non-cytotoxic concentrations (0.01-10 μg/mL, DE-71 significantly enhanced secretion of IL-1β, IL-6, CXCL8, IL-10, and TNF-α (p<0.001-0.019; n = 6 from LPS-stimulated PBMCs. IFN-γ, TNF-α, IL-17A, and IL-17F (p = <0.001-0.043; n = 6 secretion were enhanced from PHA-L-stimulated PBMCs as well. Secretion of IL-1β, IL-2, IL-10, IL-8 and IL-6 was not significantly affected by DE-71.We demonstrate an enhancing effect of DE-71 on cytokine production by normal human PBMCs stimulated with LPS or PHA-L ex vivo.

  6. Technology Development Roadmap: A Technology Development Roadmap for a Future Gravitational Wave Mission

    Science.gov (United States)

    Camp, Jordan; Conklin, John; Livas, Jeffrey; Klipstein, William; McKenzie, Kirk; Mueller, Guido; Mueller, Juergen; Thorpe, James Ira; Arsenovic, Peter; Baker, John; Bender, Peter; Brinker, Edward; Crow, John; Spero, Robert; deVine Glenn; Ziemer, John

    2013-01-01

    Humankind will detect the first gravitational wave (GW) signals from the Universe in the current decade using ground-based detectors. But the richest trove of astrophysical information lies at lower frequencies in the spectrum only accessible from space. Signals are expected from merging massive black holes throughout cosmic history, from compact stellar remnants orbiting central galactic engines from thousands of close contact binary systems in the Milky Way, and possibly from exotic sources, some not yet imagined. These signals carry essential information not available from electromagnetic observations, and which can be extracted with extraordinary accuracy. For 20 years, NASA, the European Space Agency (ESA), and an international research community have put considerable effort into developing concepts and technologies for a GW mission. Both the 2000 and 2010 decadal surveys endorsed the science and mission concept of the Laser Interferometer Space Antenna (LISA). A partnership of the two agencies defined and analyzed the concept for a decade. The agencies partnered on LISA Pathfinder (LPF), and ESA-led technology demonstration mission, now preparing for a 2015 launch. Extensive technology development has been carried out on the ground. Currently, the evolved Laser Interferometer Space Antenna (eLISA) concept, a LISA-like concept with only two measurement arms, is competing for ESA's L2 opportunity. NASA's Astrophysics Division seeks to be a junior partner if eLISA is selected. If eLISA is not selected, then a LISA-like mission will be a strong contender in the 2020 decadal survey. This Technology Development Roadmap (TDR) builds on the LISA concept development, the LPF technology development, and the U.S. and European ground-based technology development. The eLISA architecture and the architecture of the Mid-sized Space-based Gravitational-wave Observatory (SGO Mid)-a competitive design with three measurement arms from the recent design study for a NASA

  7. Fuel Pathway Integration Technical Team Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    None

    2013-06-01

    The Fuel Pathway Integration Technical Team (FPITT) supports the U.S. DRIVE Partnership (the Partnership) in the identification and evaluation of implementation scenarios for fuel cell technology pathways, including hydrogen and fuel cell electric vehicles in the transportation sector, both during a transition period and in the long term.

  8. EU Energy Roadmap 2050. Surrogate for an ambitious decarbonisation policy?; EU-Energy Roadmap 2050. Surrogat fuer eine ehrgeizige Dekarbonisierungspolitik?

    Energy Technology Data Exchange (ETDEWEB)

    Geden, Oliver; Fischer, Severin [Stiftung Wissenschaft und Politik (SWP), Berlin (Germany)

    2012-10-15

    When the 'Energy Roadmap 2050' of the European Commission was first published, it was presented as a blueprint of the future development of the European power supply system. Now, just a few months later, it becomes clear that the impending decisions on the energy and climate policy goals of the EU beyond 2020 will be influenced only marginally by the roadmap of the EU Commission: There is too much opposition in the 27 EU member states. On the one hand, the consensus reached in 2007, i.e. that energy policy should be oriented along climate policy goals, has been broken. On the other hand, the EU member states are not prepared to accept restrictions of national sovereignty in the energy policy sector.

  9. Commercializing light-duty plug-in/plug-out hydrogen-fuel-cell vehicles: "Mobile Electricity" technologies and opportunities

    Science.gov (United States)

    Williams, Brett D.; Kurani, Kenneth S.

    Starting from the premise that new consumer value must drive hydrogen-fuel-cell-vehicle (H 2FCV) commercialization, a group of opportunities collectively called "Mobile Electricity" is characterized. Mobile Electricity (Me-) redefines H 2FCVs as innovative products able to import and export electricity across the traditional vehicle boundary. Such vehicles could provide home recharging and mobile power, for example for tools, mobile activities, emergencies, and electric-grid-support services. This study integrates and extends previous analyses of H 2FCVs, plug-in hybrids, and vehicle-to-grid (V2G) power. Further, it uses a new electric-drive-vehicle and vehicular-distributed-generation model to estimate zero-emission-power versus zero-emission-driving tradeoffs, costs, and grid-support revenues for various electric-drive vehicle types and levels of infrastructure service. By framing market development in terms of new consumer value flowing from Me-, this study suggests a way to move beyond the battery versus fuel-cell zero-sum game and towards the development of integrated plug-in/plug-out hybrid platforms. As one possible extension of this Me- product platform, H 2FCVs might supply clean, high-power, and profitable Me- services as the technologies and markets mature.

  10. Web-based Academic Roadmaps for Careers in the Geosciences

    Science.gov (United States)

    Murray, D. P.; Veeger, A. I.; Grossman-Garber, D.

    2007-12-01

    To a greater extent than most science programs, geology is underrepresented in K-12 curricula and the media. Thus potential majors have scant knowledge of academic requirements and career trajectories, and their idea of what geologists do--if they have one at all--is outdated. We have addressed these concerns by developing a dynamic, web-based academic roadmap for current and prospective students, their families, and others who are contemplating careers in the geosciences. The goals of this visually attractive "educational pathway" are to not only improve student recruitment and retention, but to empower student learning by creating better communication and advising tools that can render our undergraduate program transparent for learners and their families. Although we have developed academic roadmaps for four environmental and life science programs at the University of Rhode Island, we focus here on the roadmap for the geosciences, which illustrates educational pathways along the academic and early-career continuum for current and potential (i.e., high school) students who are considering the earth sciences. In essence, the Geosciences Academic Roadmap is a "one-stop'" portal to the discipline. It includes user- friendly information about our curriculum, outcomes (which at URI are tightly linked to performance in courses and the major), extracurricular activities (e.g., field camp, internships), careers, graduate programs, and training. In the presentation of this material extensive use is made of streaming video, interviews with students and earth scientists, and links to other relevant sites. Moreover, through the use of "Hot Topics", particular attention is made to insure that examples of geoscience activities are not only of relevance to today's students, but show geologists using the modern methods of the discipline in exciting ways. Although this is a "work-in-progress", evaluation of the sites, by high school through graduate students, has been strongly

  11. Comparative evaluation of cytotoxicity of cadmium in rat liver cells cultured in serum-containing medium and commercially available serum-free medium.

    Science.gov (United States)

    Latinwo, Lekan M; Badisa, Veera L D; Odewumi, Caroline O; Ikediobi, Christopher O; Badisa, Ramesh B; Brooks-Walter, Alexis; Lambert, Ayuk-Takem T; Nwoga, Jude

    2008-07-01

    Cadmium (Cd) is an industrial pollutant and carcinogenic metal. Most in vitro Cd toxicity studies have been carried out in various cell lines cultured in 10% fetal bovine serum (FBS) containing medium. In this report, we compared the toxic effect of Cd (0-300 microM) on cell growth, total RNA, total proteins, and antioxidant enzymes in rat normal liver cells cultured in medium with 10% FBS or commercially available serum-free medium for 4 or 8 hours. With Cd concentration at above 100 microM, the total levels of RNA, protein and cell growth decreased in serum-containing medium, while their levels increased in serum-free medium compared to the controls. The glutathione peroxidase and glutathione reductase levels were lower in serum-free medium than in serum-containing medium, indicating less oxidative stress in cells grown in serum-free medium. These results clearly suggest that Cd showed higher toxicity to liver cells grown in serum-containing medium in comparison to commercially available serum-free medium. It is speculated that albumin and other substances present in commercial serum-free medium chelated Cd and thereby protected these cells against Cd toxicity. Even under in vivo conditions, cadmium enters into various organs after passing through blood which contains serum. Based on these studies, it appears that media containing serum may be ideal for in vivo toxicity correlation studies with animal cells.

  12. Designing Program Roadmaps to Catalyze Community Formation: A Case Study of the Long-Term Stewardship Science and Technology Roadmapword

    Energy Technology Data Exchange (ETDEWEB)

    Dixon, Brent; Hanson, Duane; Matthern, Gretchen

    2003-02-27

    A number of broad perspective technology roadmaps have been developed in the last few years as tools for coordinating nation-wide research in targeted areas. These roadmaps share a common characteristic of coalescing the associated stakeholder groups into a special-interest community that is willing to work cooperatively in achieving the roadmap goals. These communities are key to roadmap implementation as they provide the collaborative energy necessary to obtain the political support and funding required for identified science and technology development efforts. This paper discusses the relationship between roadmaps and special-interest communities, using the recently drafted Department of Energy's Long-Term Stewardship Science and Technology Roadmap as a case study. Specific aspects this roadmap's design facilitated the development of a long-term stewardship community while specific realities during roadmap development impacted the realization of the design.

  13. The 2015 super-resolution microscopy roadmap

    NARCIS (Netherlands)

    Hell, Stefan W.; Sahl, Steffen J.; Bates, Mark; Zhuang, Xiaowei; Heintzmann, Rainer; Booth, Martin J.; Bewersdorf, Joerg; Shtengel, Gleb; Hess, Harald; Tinnefeld, Philip; Honigmann, Alf; Jakobs, Stefan; Testa, Ilaria; Cognet, Laurent; Lounis, Brahim; Ewers, Helge; Davis, Simon J.; Eggeling, Christian; Klenerman, David; Willig, Katrin I.; Vicidomini, Giuseppe; Castello, Marco; Diaspro, Alberto; Cordes, Thorben

    2015-01-01

    Far-field optical microscopy using focused light is an important tool in a number of scientific disciplines including chemical, (bio) physical and biomedical research, particularly with respect to the study of living cells and organisms. Unfortunately, the applicability of the optical microscope is

  14. Comparative studies on the chemical and cell-based antioxidant activities and antitumor cell proliferation properties of soy milk manufactured by conventional and commercial UHT methods.

    Science.gov (United States)

    Xu, Baojun; Chang, Sam K C; Liu, Zhisheng; Yuan, Shaohong; Zou, Yanping; Tan, Yingying

    2010-03-24

    The aims of this work were to compare antiproliferation, antioxidant activities and total phytochemicals and individual isoflavone profiles in soy milk processed by various methods including traditional stove cooking, direct steam injection, direct ultrahigh temperature (UHT), indirect UHT, and a two-stage simulated industry method, and a selected commercial soy milk product. Various processing methods significantly affected total saponin, phytic acid, and total phenolic content and individual isoflavone distribution. The laboratory UHT and the two-stage processed soy milk exhibited relatively higher total phenolic content, total flavonoid content, saponin and phytic acid than those processed by the traditional and steam processed methods. Thermal processing caused obvious intertransformation but did not cause severe degradation except for breaking down of aglycons. Thermal processing significantly increased antioxidant capacities of soy milk determined by chemical analyses, but decreased cellular antioxidant capacities as compared to the raw soy milk. The raw and all processed soy milk exhibited antipoliferative activities against human HL-60 leukemia cells, AGS gastric tumor cells, and DU145 prostate cancer cells in a dose-dependent manner. The raw soy milk, but not the processed soy milk, exhibited a dose-dependent antiproliferative effect against colorectal adenocarcinoma Caco-2 cells. Taken together, these results indicate that various thermal processing methods change not only phytochemcials but also potential health-promoting effects of soy milk.

  15. 76 FR 66040 - NIST Framework and Roadmap for Smart Grid Interoperability Standards, Release 2.0 (Draft...

    Science.gov (United States)

    2011-10-25

    ... National Institute of Standards and Technology NIST Framework and Roadmap for Smart Grid Interoperability... and Technology (NIST) seeks comments on the draft NIST Framework and Roadmap for Smart Grid..., 2011. The entire draft version of the NIST Framework and Roadmap for Smart Grid...

  16. Science and technology roadmap for graphene, related two-dimensional crystals, and hybrid systems

    DEFF Research Database (Denmark)

    Ferrari, Andrea C.; Bonaccorso, Francesco; Falko, Vladimir;

    2015-01-01

    We present the science and technology roadmap (STR) for graphene, related twodimensional (2d) crystals, and hybrid systems, targeting an evolution in technology, that might lead to impacts and benefits reaching into most areas of society. The roadmap was developed within the framework of the Euro...

  17. NASA's New Thermal Management Systems Roadmap; Whats in it, What it Means

    Science.gov (United States)

    Swanson, Ted

    2016-01-01

    In July of 2015 NASA publically released a new set of Technology Area Roadmaps that will be used to help guide future NASA-funded technology development efforts. One of these was the Thermal Management Systems Roadmap, often identified as TA14. This Roadmap identifies the time sequencing and interdependencies of high priority, advanced thermal control technology for the next 5 to 20 years. Available funding limits the development of new technology. The Roadmaps are the first step in the process of prioritizing HQ-supported technology funding. The 2015 Roadmaps are focused on planned mission architectures and needs, as identified in the NRC-led science Decadals and HEOMD's Design Reference Missions. Additionally, the 2015 Roadmaps focus on "applied " R&D as opposed to more basic research. The NASA Mission Directorates were all closely involved in development of 2015 Roadmaps, and an extensive external review was also conducted. This talk will discuss the Technology Roadmaps in general, and then focus on the specific technologies identified for TA 14, Thermal Management Systems.

  18. Commercialization scenarios of polymer electrolyte membrane fuel cell applications for stationary power generation in the United States by the year 2015

    Energy Technology Data Exchange (ETDEWEB)

    Millett, Stephen; Mahadevan, Kathya [Battelle Memorial Institute, 505 King Avenue, Columbus, OH 43201 (United States)

    2005-10-04

    Battelle is identifying the most likely markets and economic impacts of stationary polymer electrolyte membrane (PEM) fuel cells in the range of 1-250kW in the U.S. by the year 2015. For this task, Battelle is using the Interactive Future Simulations (IFS(TM)), an analytical modeling and forecasting tool that uses expert judgment, trend analysis, and cross-impact analysis methods to generate most likely future conditions for PEM fuel cell applications, market acceptance, commercial viability, and economic impacts. The cross-impact model contains 28 descriptors including commercial and technological advances in both polymer electrolyte membrane (PEM) fuel cells and fossil fuel technologies, sources of hydrogen, investments, public policy, environmental regulation, value to consumers, commercialization leadership, modes of generation, and the reliability and prices of grid electricity. One likely scenario to the year 2015 is that the PEM fuel cells will be limited to commercial and industrial customers in the range of 50-200kW with a market size less than US$ 5 billion a year. (author)

  19. Hydrogen delivery technology rRoadmap

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2005-11-01

    Hydrogen holds the long-term potential to solve two critical problems related to the energy infrastructure: U.S. dependence on foreign oil and U.S. emissions of greenhouse gases and pollutants. The U.S. transportation sector is almost completely reliant on petroleum, over half of which is currently imported, and tailpipe emissions remain one of the country’s key air quality concerns. Fuel cell vehicles operating on hydrogen produced from domestically available resources – including renewable resources, coal with carbon sequestration, or nuclear energy – would dramatically decrease greenhouse gases and other emissions, and would reduce dependence on oil from politically volatile regions of the world. Clean, domestically-produced hydrogen could also be used to generate electricity in stationary fuel cells at power plants, further extending national energy and environmental benefits.

  20. Investigation of Path Dependence in Commercial Li-ion Cells Chosen for PHEV Duty Cycle Protocols (paper)

    Energy Technology Data Exchange (ETDEWEB)

    Kevin L. Gering

    2011-04-01

    Path dependence is emerging as a premier issue of how electrochemical cells age in conditions that are diverse and variable in the time domain. For example, lithium-ion cells in a vehicle configuration will experience a variable combination of usage and rest periods over a range of temperature and state of charge (SOC). This is complicated by the fact that some aging can actually become worse (or better) when a lithium-ion cell is idle for extended periods under calendar-life (calL) aging, as opposed to cycle-life (cycL) conditions where the cell is used within a predictable schedule. The purpose of this study is to bridge the gap between highly idealized and controlled laboratory test conditions and actual field conditions regarding PHEV applications, so that field-type aging mechanisms can be mimicked and quantified in a repeatable laboratory setting. The main parameters are the magnitude and frequency of the thermal cycling, looking at isothermal, mild, and severe scenarios. To date, little is known about Li-ion aging effects caused by thermal cycling superimposed onto electrochemical cycling, and related path dependence. This scenario is representative of what Li-ion batteries will experience in vehicle service, where upon the typical start of a HEV/PHEV, the batteries will be cool or cold, will gradually warm up to normal temperature and operate there for a time, then will cool down after the vehicle is turned off. Such thermal cycling will occur thousands of times during the projected life of a HEV/PHEV battery pack. We propose to quantify the effects of thermal cycling on Li-ion batteries using a representative chemistry that is commercially available. The secondary Li-ion cells used in this study are of the 18650 configuration, have a nominal capacity rating of 1.9 Ah, and consist of a {LiMn2O4 + LiMn(1/3)Ni(1/3)Co(1/3)O2} cathode and a graphite anode. Electrochemical cycling is based on PHEV-relevant cycle-life protocols that are a combination of charge

  1. Extremely Large Telescope Project Selected in ESFRI Roadmap

    Science.gov (United States)

    2006-10-01

    In its first Roadmap, the European Strategy Forum on Research Infrastructures (ESFRI) choose the European Extremely Large Telescope (ELT), for which ESO is presently developing a Reference Design, as one of the large scale projects to be conducted in astronomy, and the only one in optical astronomy. The aim of the ELT project is to build before the end of the next decade an optical/near-infrared telescope with a diameter in the 30-60m range. ESO PR Photo 40/06 The ESFRI Roadmap states: "Extremely Large Telescopes are seen world-wide as one of the highest priorities in ground-based astronomy. They will vastly advance astrophysical knowledge allowing detailed studies of inter alia planets around other stars, the first objects in the Universe, super-massive Black Holes, and the nature and distribution of the Dark Matter and Dark Energy which dominate the Universe. The European Extremely Large Telescope project will maintain and reinforce Europe's position at the forefront of astrophysical research." Said Catherine Cesarsky, Director General of ESO: "In 2004, the ESO Council mandated ESO to play a leading role in the development of an ELT for Europe's astronomers. To that end, ESO has undertaken conceptual studies for ELTs and is currently also leading a consortium of European institutes engaged in studying enabling technologies for such a telescope. The inclusion of the ELT in the ESFRI roadmap, together with the comprehensive preparatory work already done, paves the way for the next phase of this exciting project, the design phase." ESO is currently working, in close collaboration with the European astronomical community and the industry, on a baseline design for an Extremely Large Telescope. The plan is a telescope with a primary mirror between 30 and 60 metres in diameter and a financial envelope of about 750 m Euros. It aims at more than a factor ten improvement in overall performance compared to the current leader in ground based astronomy: the ESO Very Large

  2. Policy and Technology Readiness: Engaging the User and Developer Community to Develop a Research Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    Olson, Jarrod; Barr, Jonathan L.; Burtner, Edwin R.; West, Curtis L.; Kielman, Joseph

    2015-05-16

    A key challenge for research roadmapping in the crisis response and management domain is articulation of a shared vision that describes what the future can and should include. Visioning allows for far-reaching stakeholder engagement that can properly align research with stakeholders needs. Engagement includes feedback from researchers, policy makers, general public, and end-users on technical and non-technical factors. This work articulates a process and framework for the construction and maintenance of a stakeholder-centric research vision and roadmap in the emergency management domain. This novel roadmapping process integrates three pieces: analysis of the research and technology landscape, visioning, and stakeholder engagement. Our structured engagement process elicits research foci for the roadmap based on relevance to stakeholder mission, identifies collaborators, and builds consensus around the roadmap priorities. We find that the vision process and vision storyboard helps SMEs conceptualize and discuss a technology's strengths, weaknesses, and alignment with needs

  3. Zero expansion glass ceramic ZERODUR® roadmap for advanced lithography

    Science.gov (United States)

    Westerhoff, Thomas; Jedamzik, Ralf; Hartmann, Peter

    2013-04-01

    The zero expansion glass ceramic ZERODUR® is a well-established material in microlithography in critical components as wafer- and reticle-stages, mirrors and frames in the stepper positioning and alignment system. The very low coefficient of thermal expansion (CTE) and its extremely high CTE homogeneity are key properties to achieve the tight overlay requirements of advanced lithography processes. SCHOTT is continuously improving critical material properties of ZERODUR® essential for microlithography applications according to a roadmap driven by the ever tighter material specifications broken down from the customer roadmaps. This paper will present the SCHOTT Roadmap for ZERODUR® material property development. In the recent years SCHOTT established a physical model based on structural relaxation to describe the coefficient of thermal expansion's temperature dependence. The model is successfully applied for the new expansion grade ZERODUR® TAILORED introduced to the market in 2012. ZERODUR® TAILORED delivers the lowest thermal expansion of ZERODUR® products at microlithography tool application temperature allowing for higher thermal stability for tighter overlay control in IC production. Data will be reported demonstrating the unique CTE homogeneity of ZERODUR® and its very high reproducibility, a necessary precondition for serial production for microlithography equipment components. New data on the bending strength of ZERODUR® proves its capability to withstand much higher mechanical loads than previously reported. Utilizing a three parameter Weibull distribution it is possible to derive minimum strength values for a given ZERODUR® surface treatment. Consequently the statistical uncertainties of the earlier approach based on a two parameter Weibull distribution have been eliminated. Mechanical fatigue due to stress corrosion was included in a straightforward way. The derived formulae allows calculating life time of ZERODUR® components for a given stress

  4. Roadmap to a Sustainable Structured Trusted Employee Program

    Energy Technology Data Exchange (ETDEWEB)

    Coates, Cameron W [ORNL; Eisele, Gerhard R [ORNL

    2013-08-01

    Organizations (facility, regulatory agency, or country) have a compelling interest in ensuring that individuals who occupy sensitive positions affording access to chemical biological, radiological and nuclear (CBRN) materials facilities and programs are functioning at their highest level of reliability. Human reliability and human performance relate not only to security but also focus on safety. Reliability has a logical and direct relationship to trustworthiness for the organization is placing trust in their employees to conduct themselves in a secure, safe, and dependable manner. This document focuses on providing an organization with a roadmap to implementing a successful and sustainable Structured Trusted Employee Program (STEP).

  5. Italy 100% Renewable: A Suitable Energy Transition Roadmap

    CERN Document Server

    Meneguzzo, Francesco; Albanese, Lorenzo; Pagliaro, Mario

    2016-01-01

    We outline a realistic energy transition roadmap for Italy, in which the whole energy demand is met by electricity generated by low cost renewable energy technologies, namely solar photovoltaic, wind and hydroelectric power. We assess the amount of extra power and storage capacity to be installed along with costs, return on investment and payback time. Based on cost, renewable nature and scalability, storage in energy dense polysaccharides enzymatically synthesized from carbon dioxide, water and surplus electricity is proposed to meet the significant storage requirements.

  6. Finding a roadmap to achieve large neuromorphic hardware systems.

    Science.gov (United States)

    Hasler, Jennifer; Marr, Bo

    2013-01-01

    Neuromorphic systems are gaining increasing importance in an era where CMOS digital computing techniques are reaching physical limits. These silicon systems mimic extremely energy efficient neural computing structures, potentially both for solving engineering applications as well as understanding neural computation. Toward this end, the authors provide a glimpse at what the technology evolution roadmap looks like for these systems so that Neuromorphic engineers may gain the same benefit of anticipation and foresight that IC designers gained from Moore's law many years ago. Scaling of energy efficiency, performance, and size will be discussed as well as how the implementation and application space of Neuromorphic systems are expected to evolve over time.

  7. Practical roadmap and limits to nanostructured photovoltaics.

    Science.gov (United States)

    Lunt, Richard R; Osedach, Timothy P; Brown, Patrick R; Rowehl, Jill A; Bulović, Vladimir

    2011-12-22

    The significant research interest in the engineering of photovoltaic (PV) structures at the nanoscale is directed toward enabling reductions in PV module fabrication and installation costs as well as improving cell power conversion efficiency (PCE). With the emergence of a multitude of nanostructured photovoltaic (nano-PV) device architectures, the question has arisen of where both the practical and the fundamental limits of performance reside in these new systems. Here, the former is addressed a posteriori. The specific challenges associated with improving the electrical power conversion efficiency of various nano-PV technologies are discussed and several approaches to reduce their thermal losses beyond the single bandgap limit are reviewed. Critical considerations related to the module lifetime and cost that are unique to nano-PV architectures are also addressed. The analysis suggests that a practical single-junction laboratory power conversion efficiency limit of 17% and a two-cell tandem power conversion efficiency limit of 24% are possible for nano-PVs, which, when combined with operating lifetimes of 10 to 15 years, could position them as a transformational technology for solar energy markets.

  8. Comparative Study of Surface Temperature Behavior of Commercial Li-Ion Pouch Cells of Different Chemistries and Capacities by Infrared Thermography

    Directory of Open Access Journals (Sweden)

    Shovon Goutam

    2015-08-01

    Full Text Available The non-uniform surface temperature distribution of a battery cell results from complex reactions inside the cell and makes efficient thermal management a challenging task. This experimental work attempts to determine the evolution of surface temperature distribution of three pouch type commercial cells: Nickel Manganese Cobalt oxide (NMC-based 20 Ah cell, Lithium Iron Phosphate (LFP 14 Ah, and Lithium Titanate Oxide (LTO 5 Ah battery cell by using contact thermistor and infrared (IR thermography. High current (up to 100 A continuous charge/discharge and high current (80 A micro pulse cycling profile were applied on the cells. It was found that thermistor based temperature profile varied cell to cell, especially the LTO cell. Among the investigated cells, the NMC cell shows highest temperature rise and the LTO cell the lowest rise. IR (Infrared images revealed the spatial distribution of surface temperature, in particular the location of the hottest region varies depending not only on the geometrical and material properties of the cell, but also the type of loads applied on the cells. Finally, a modeling perspective of the cell temperature non-uniformity is also discussed.

  9. Roadmap 2050: McKinsey and company lay down the low-carbon gauntlet to the EU

    Energy Technology Data Exchange (ETDEWEB)

    Probert, T.

    2010-05-15

    A report issued by the European Climate Foundation, 'Roadmap 2050: A practical guide to a prosperous low-carbon Europe' appears to have dispelled concerns that the decarbonization of the European Union's power sector is profligate fantasy. The overall conclusion of the report is that by 2050, Europe could achieve an economy-wide, affordable reduction of GHG emission of at least 80% compared to 1990 levels. Realizing this radical transformation, however, requires fundamental changes to the European energy system. This would only be possible with a nearly zero-carbon power supply that emits 5% or less of baseline GHG emissions. Such a supply could be realised by further developing and deploying low carbon technologies that are already commercially available or in later-stage development like CCS, and by expanding the trans-European transmission grid. 1 ref., 3 figs.

  10. Enabling the Distributed Generation Market of High Temperature Fuel Cell and Absorption Chiller Systems to Support Critical and Commercial Loads

    Science.gov (United States)

    DiMola, Ashley M.

    Buildings account for over 18% of the world's anthropogenic Greenhouse Gas (GHG) emissions. As a result, a technology that can offset GHG emissions associated with buildings has the potential to save over 9 Giga-tons of GHG emissions per year. High temperature fuel cell and absorption chiller (HTFC/AC) technology offers a relatively low-carbon option for meeting cooling and electric loads for buildings while producing almost no criteria pollutants. GHG emissions in the state of California would decrease by 7.48 million metric tons per year if every commercial building in the State used HTFC/AC technology to meet its power and cooling requirements. In order to realize the benefits of HTFC/AC technology on a wide scale, the distributed generation market needs to be exposed to the technology and informed of its economic viability and real-world potential. This work characterizes the economics associated with HTFC/AC technology using select scenarios that are representative of realistic applications. The financial impacts of various input factors are evaluated and the HTFC/AC simulations are compared to the economics of traditional building utilities. It is shown that, in addition to the emissions reductions derived from the systems, HTFC/AC technology is financially preferable in all of the scenarios evaluated. This work also presents the design of a showcase environment, centered on a beta-test application, that presents (1) system operating data gathered using a custom data acquisition module, and (2) HTFC/AC technology in a clear and approachable manner in order to serve the target audience of market stakeholders.

  11. Astrobiology: A Roadmap for Charting Life in the Universe

    Science.gov (United States)

    DesMarais, David J.; DeVincezi, D. (Technical Monitor)

    2002-01-01

    Astrobiology is the study of the origin, evolution and distribution of life in the universe. It provides a biological perspective to many areas of NASA research. It links such endeavors as the search for habitable planets, exploration missions to Mars and the outer Solar System, efforts to understand the origins and early evolution of life, and charting the potential of life to adapt to future challenges, both on Earth and in space. Astrobiology addresses the following three basic questions, which have been asked in some form for generations. How does life begin and evolve? Does life exist elsewhere in the universe? What is future of life on Earth and beyond? The NASA Astrobiology Roadmap provides guidance for research and technology development across several NASA Enterprises: Space Science, Earth Science, and the Human Exploration and Development of Space. The Roadmap is formulated in terms of eight Science Goals that outline key domains of investigation that might require perhaps decades of effort to consolidate. For each of these goals, Science Objectives outline more specific high priority near-term efforts for the next three to five years. These twenty objectives will be integrated with NASA strategic planning.

  12. Adoption of Electronic Health Records: A Roadmap for India

    Science.gov (United States)

    2016-01-01

    Objectives The objective of the study was to create a roadmap for the adoption of Electronic Health Record (EHR) in India based an analysis of the strategies of other countries and national scenarios of ICT use in India. Methods The strategies for adoption of EHR in other countries were analyzed to find the crucial steps taken. Apart from reports collected from stakeholders in the country, the study relied on the experience of the author in handling several e-health projects. Results It was found that there are four major areas where the countries considered have made substantial efforts: ICT infrastructure, Policy & regulations, Standards & interoperability, and Research, development & education. A set of crucial activities were identified in each area. Based on the analysis, a roadmap is suggested. It includes the creation of a secure health network; health information exchange; and the use of open-source software, a national health policy, privacy laws, an agency for health IT standards, R&D, human resource development, etc. Conclusions Although some steps have been initiated, several new steps need to be taken up for the successful adoption of EHR. It requires a coordinated effort from all the stakeholders. PMID:27895957

  13. A Region-Based Strategy for Collaborative Roadmap Construction

    KAUST Repository

    Denny, Jory

    2015-01-01

    © Springer International Publishing Switzerland 2015. Motion planning has seen much attention over the past two decades. A great deal of progress has been made in sampling-based planning, whereby a planner builds an approximate representation of the planning space. While these planners have demonstrated success inmany scenarios, there are still difficult problems where they lack robustness or efficiency, e.g., certain types of narrow spaces. Conversely, human intuition can often determine an approximate solution to these problems quite effectively, but humans lack the speed and precision necessary to perform the corresponding low-level tasks (such as collision checking) in a timely manner. In this work, we introduce a novel strategy called Region Steering in which the user and a PRM planner work cooperatively to map the space while maintaining the probabilistic completeness property of the PRMplanner. Region Steering utilizes two-way communication to integrate the strengths of both the user and the planner, thereby overcoming the weaknesses inherent to relying on either one alone. In one communication direction, a user can input regions, or bounding volumes in the workspace, to bias sampling towards or away from these areas. In the other direction, the planner displays its progress to the user and colors the regions based on their perceived usefulness.We demonstrate that Region Steering provides roadmap customizability, reduced mapping time, and smaller roadmap sizes compared with fully automated PRMs, e.g., Gaussian PRM.

  14. National cyber defense high performance computing and analysis : concepts, planning and roadmap.

    Energy Technology Data Exchange (ETDEWEB)

    Hamlet, Jason R.; Keliiaa, Curtis M.

    2010-09-01

    There is a national cyber dilemma that threatens the very fabric of government, commercial and private use operations worldwide. Much is written about 'what' the problem is, and though the basis for this paper is an assessment of the problem space, we target the 'how' solution space of the wide-area national information infrastructure through the advancement of science, technology, evaluation and analysis with actionable results intended to produce a more secure national information infrastructure and a comprehensive national cyber defense capability. This cybersecurity High Performance Computing (HPC) analysis concepts, planning and roadmap activity was conducted as an assessment of cybersecurity analysis as a fertile area of research and investment for high value cybersecurity wide-area solutions. This report and a related SAND2010-4765 Assessment of Current Cybersecurity Practices in the Public Domain: Cyber Indications and Warnings Domain report are intended to provoke discussion throughout a broad audience about developing a cohesive HPC centric solution to wide-area cybersecurity problems.

  15. A roadmap for the synthesis of separation networks for the recovery of bio-based chemicals: Matching biological and process feasibility.

    Science.gov (United States)

    Yenkie, Kirti M; Wu, WenZhao; Clark, Ryan L; Pfleger, Brian F; Root, Thatcher W; Maravelias, Christos T

    2016-12-01

    Microbial conversion of renewable feedstocks to high-value chemicals is an attractive alternative to current petrochemical processes because it offers the potential to reduce net CO2 emissions and integrate with bioremediation objectives. Microbes have been genetically engineered to produce a growing number of high-value chemicals in sufficient titer, rate, and yield from renewable feedstocks. However, high-yield bioconversion is only one aspect of an economically viable process. Separation of biologically synthesized chemicals from process streams is a major challenge that can contribute to >70% of the total production costs. Thus, process feasibility is dependent upon the efficient selection of separation technologies. This selection is dependent on upstream processing or biological parameters, such as microbial species, product titer and yield, and localization. Our goal is to present a roadmap for selection of appropriate technologies and generation of separation schemes for efficient recovery of bio-based chemicals by utilizing information from upstream processing, separation science and commercial requirements. To achieve this, we use a separation system comprising of three stages: (I) cell and product isolation, (II) product concentration, and (III) product purification and refinement. In each stage, we review the technology alternatives available for different tasks in terms of separation principles, important operating conditions, performance parameters, advantages and disadvantages. We generate separation schemes based on product localization and its solubility in water, the two most distinguishing properties. Subsequently, we present ideas for simplification of these schemes based on additional properties, such as physical state, density, volatility, and intended use. This simplification selectively narrows down the technology options and can be used for systematic process synthesis and optimal recovery of bio-based chemicals.

  16. PVT roadmap. A European guide for the development and market introduction of PVT technology

    Energy Technology Data Exchange (ETDEWEB)

    Zondag, H.A.; Van Helden, W.G.J.; Bakker, M. [ECN Renewable Energy in the Built Environment DEGO, Petten (Netherlands); Affolter, P. [Solstis, Lausanne (Switzerland); Eisenmann, W. [Institut fuer Solarenergieforschung ISFH, Emmerthal (Germany); Fechner, H. [Arsenal Research, Vienna (Austria); Rommel, M. [Fraunhofer ISE, Freiburg (Germany); Schaap, A. [Ecofys, Utrecht (Netherlands); Soerensen, H. [Esbensen, Copenhagen (Denmark); Tripanagnostopoulos, Y. [University of Patras, Patras (Greece)

    2006-06-15

    The aim of the roadmap is to identify promising markets for PVT (PhotoVoltaic Thermal) technology , and to identify the economical, policy, legislative and technical bottlenecks. In addition, the roadmap wants to inform the parties in the market on PVT. It thereby targets a broad range of professionals, including policy makers, solar manufacturers, installers and researchers. This work has been carried out within the PVT forum project, which is part of the EU-supported project PV-Catapult. The aim of PVT Forum is to lay the foundations for a large-scale introduction of PVT technology in Europe by means of this roadmap. In order to construct the roadmap, a two-step approach was taken. As a first step, PVT experts, PV and solar thermal industries and other stakeholders were brought together in two workshops, connected to the PVSEC 2004 in Paris and the Eurosun conference 2004 in Freiburg, to identify drivers and barriers for PVT. The results of these two workshops, that were presented in two workshop reports, were used as input for the roadmap presented here. As a second step, the PVT roadmap was written, formulating the necessary actions that should be taken on short, medium and long term in order to enlarge the market for PVT products. The chapters of the roadmap are written and reviewed by the various participants in PVT Forum. These participants have been selected for this project on the basis of their contribution to PVT development over the last years.

  17. Analysis of the thermal and electrical behavior of commercial photovoltaic cells in inverse operation; Analisis del comportamiento termico y electrico de celulas fotovoltaicas comerciales en operacion inversa

    Energy Technology Data Exchange (ETDEWEB)

    Margineda, D.; Alonso-Garcia, M. C.; Sanchez-Friera, P.

    2008-07-01

    In order to analyse the thermal and electrical behaviour of commercial solar cells in reverse operation photovoltaic cells of the same type, but different class (different efficiency in the same type cell) were selected. electrical characterisation of the samples was performed through I-V curve measurements in direct and reverse bias, what gave information about the type of reverse I-V characteristics. besides, infrared characterisation showed temperature distributions along cell surface, pointing out localised heating that could cause hot-spots. From both characterisations (electrical and thermal) it is possible to obtain relations between the class of the cell, the type of reverse characteristics and maximum temperatures in case of partial shading or faulty operation. (Author)

  18. A Governance Roadmap and Framework for EarthCube

    Science.gov (United States)

    Governance Steering Committee, EarthCube

    2013-04-01

    EarthCube is a process and an outcome, established to transform the conduct of research through the development of community-guided cyberinfrastructure for the Geosciences as the prototype for potential deployment across all domain sciences. EarthCube aims to create a knowledge management system and infrastructure that integrates all Earth system and human dimensions data in an open transparent, and inclusive manner. EarthCube requires broad community participation in concept, framework, and implementation and must not be hindered by rigid preconceptions. We discovered widely varying interpretations, expectations, and assumptions about governance among EarthCube participants. Our definition of governance refers to the processes, structure and organizational elements that determine, within an organization or system of organizations, how power is exercised, how stakeholders have their say, how decisions are made, and how decision makers are held accountable. We have learned, from historic infrastructure case studies, background research on governance and from community feedback during this roadmap process, that other types of large-scale, complex infrastructures, including the Internet, have no central control, administration, or management. No national infrastructure that we examined is governed by a single entity, let alone a single governance archetype. Thus we feel the roadmap process must accommodate a governance system or system of systems that may have a single governing entity, particularly at the start, but can evolve into a collective of governing bodies as warranted, in order to be successful. A fast-track process during Spring, 2012 culminated in a Governance Roadmap delivered to an NSF-sponsored charrette in June with an aggressive timetable to define and implement a governance structure to enable the elements of EarthCube to become operational expeditiously. Our goal is to help ensure the realization of this infrastructure sooner, more efficiently, and

  19. From vision to action: roadmapping as a strategic method and tool to implement climate change adaptation - the example of the roadmap 'water sensitive urban design 2020'.

    Science.gov (United States)

    Hasse, J U; Weingaertner, D E

    2016-01-01

    As the central product of the BMBF-KLIMZUG-funded Joint Network and Research Project (JNRP) 'dynaklim - Dynamic adaptation of regional planning and development processes to the effects of climate change in the Emscher-Lippe region (North Rhine Westphalia, Germany)', the Roadmap 2020 'Regional Climate Adaptation' has been developed by the various regional stakeholders and institutions containing specific regional scenarios, strategies and adaptation measures applicable throughout the region. This paper presents the method, elements and main results of this regional roadmap process by using the example of the thematic sub-roadmap 'Water Sensitive Urban Design 2020'. With a focus on the process support tool 'KlimaFLEX', one of the main adaptation measures of the WSUD 2020 roadmap, typical challenges for integrated climate change adaptation like scattered knowledge, knowledge gaps and divided responsibilities but also potential solutions and promising chances for urban development and urban water management are discussed. With the roadmap and the related tool, the relevant stakeholders of the Emscher-Lippe region have jointly developed important prerequisites to integrate their knowledge, to clarify vulnerabilities, adaptation goals, responsibilities and interests, and to foresightedly coordinate measures, resources, priorities and schedules for an efficient joint urban planning, well-grounded decision-making in times of continued uncertainties and step-by-step implementation of adaptation measures from now on.

  20. Realizing the next generation of CPV cells using transfer printing

    Science.gov (United States)

    Lumb, Matthew P.; Schmieder, Kenneth J.; González, María; Mack, Shawn; Yakes, Michael K.; Meitl, Matthew; Burroughs, Scott; Ebert, Chris; Bennett, Mitchell F.; Forbes, David V.; Sheng, Xing; Rogers, John A.; Walters, Robert J.

    2015-09-01

    Transfer-printing is an important, commercial technology for manufacturing state of the art CPV modules, and has emerged recently as a key enabling technology for the realization of ultra-high-efficiency, mechanically stacked III-V solar cells with low cost. This paper presents the latest results for microscale CPV cells grown on GaAs, InP and GaSb substrates for ultra-high-efficiency, four-terminal, mechanically stacked architectures. The latest findings from a combination of modeling, growth, processing and characterization of single and multijunction solar cells are described, and the roadmap to the long-term goal of using transfer-printing to produce the first solar cell with 50% conversion efficiency is outlined.

  1. Situation awareness of active distribution network: roadmap, technologies, and bottlenecks

    DEFF Research Database (Denmark)

    Lin, Jin; Wan, Can; Song, Yonghua

    2016-01-01

    With the rapid development of local generation and demand response, the active distribution network (ADN), which aggregates and manages miscellaneous distributed resources, has moved from theory to practice. Secure and optimal operations now require an advanced situation awareness (SA) system so...... in the project of developing an SA system as the basic component of a practical active distribution management system (ADMS) deployed in Beijing, China, is presented. This paper reviews the ADN’s development roadmap by illustrating the changes that are made in elements, topology, structure, and control scheme....... Taking into consideration these hardware changes, a systematic framework is proposed for the main components and the functional hierarchy of an SA system for the ADN. The SA system’s implementation bottlenecks are also presented, including, but not limited to issues in big data platform, distribution...

  2. Roadmap NRK 2012-2030; Routekaart NRK 2012-2030

    Energy Technology Data Exchange (ETDEWEB)

    Krebbekx, J.; Duivenvoorde, G.; De Wolf, W. [Berenschot Groep, Utrecht (Netherlands); Lenselink, J. [Energy Experts International, Huissen (Netherlands)

    2012-01-15

    This roadmap identifies how RKI companies (rubber and synthetic materials) can create new revenue opportunities: development of sustainable products, switching from petroleum to carbon chains from biobased materials, closing the material chain (reuse/recycling). Also within their own organizations more efficiency can be achieved by continuing to invest in innovation in processes and innovation in the organization itself. A selective overview is given of innovation projects [Dutch] In deze routekaart wordt aangegeven op welke wijze RKI-bedrijven (rubber en kunststoffen) nieuwe omzetkansen kunnen creeren: ontwikkelen van duurzame producten; overschakelen van aardolie naar koolstofketens uit biobased materialen; sluiten van de materiaalketen (hergebruik/recycling). Ook binnen de eigen organisatie kan er meer rendement worden behaald door te blijven investeren in innovatie in de eigen processen en innovatie in de eigen organisatie. Er is een overzicht gegeven van alle mogelijke verzamelde en geselecteerde innovatieprojecten.

  3. Analysis on Technology Roadmap of Agricultural Equipment Industry in Chongqing

    Institute of Scientific and Technical Information of China (English)

    Chongjing; TAN; Jin; YE; Shi; YANG

    2014-01-01

    Since the subsidizing agricultural machine purchase was launched in 2004,the agriculture equipment industry in Chongqing has progressed by leaps and bounds,but it is still faced with a few urgent problems,which requires the coordination of stakeholders,with an aim to establish a clear direction of the development of industry and a technology route. With planting industry as an example,this paper applies the principle and method of industry technology roadmap to analyse the market demand,industry target,technology barrier and R & D demand of agricultural equipment industry in Chongqing. Based on the results,the top technology R & D items of agricultural equipment industry in Chongqing are obtained. Finally,the following suggestions are put forward: integrating resources,constructing platform and improving innovation ability; constructing agricultural industry park and promoting clustered development of agricultural equipment industry; strengthening finance and taxation support; strengthening construction of agricultural mechanization infrastructure; substantially developing socialized service of agricultural machinery.

  4. The 2016 oxide electronic materials and oxide interfaces roadmap

    DEFF Research Database (Denmark)

    Lorenz, M.; Rao, M. S. Ramachandra; Venkatesan, T.

    2016-01-01

    Oxide electronic materials provide a plethora of possible applications and offer ample opportunity for scientists to probe into some of the exciting and intriguing phenomena exhibited by oxide systems and oxide interfaces. In addition to the already diverse spectrum of properties, the nanoscale...... form of oxides provides a new dimension of hitherto unknown phenomena due to the increased surface-to-volume ratio. Oxide electronic materials are becoming increasingly important in a wide range of applications including transparent electronics, optoelectronics, magnetoelectronics, photonics...... of these materials to understand the tunability of their properties and the novel properties that evolve due to their nanostructured nature is another facet of the challenge. The research related to the oxide electronic field is at an impressionable stage, and this has motivated us to contribute with a roadmap...

  5. Roadmap for Agriculture Biomass Feedstock Supply in the United States

    Energy Technology Data Exchange (ETDEWEB)

    J. Richard Hess; Thomas D. Foust; Reed Hoskinson; David Thompson

    2003-11-01

    The Biomass Research and Development Technical Advisory Committee established a goal that biomass will supply 5% of the nation’s power, 20% of its transportation fuels, and 25% of its chemicals by 2030. These combined goals are approximately equivalent to 30% of the country’s current petroleum consumption. The benefits of a robust biorefinery industry supplying this amount of domestically produced power, fuels, and products are considerable, including decreased demand for imported oil, revenue to the depressed agricultural industry, and revitalized rural economies. A consistent supply of highquality, low-cost feedstock is vital to achieving this goal. This biomass roadmap defines the research and development (R&D) path to supplying the feedstock needs of the biorefinery and to achieving the important national goals set for biomass. To meet these goals, the biorefinery industry must be more sustainable than the systems it will replace. Sustainability hinges on the economic profitability of all participants, on environmental impact of every step in the process, and on social impact of the product and its production. In early 2003, a series of colloquies were held to define and prioritize the R&D needs for supplying feedstock to the biorefinery in a sustainable manner. These colloquies involved participants and stakeholders in the feedstock supply chain, including growers, transporters, equipment manufacturers, and processors as well as environmental groups and others with a vested interest in ensuring the sustainability of the biorefinery. From this series of colloquies, four high-level strategic goals were set for the feedstock area: • Biomass Availability – By 2030, 1 billion dry tons of lignocellulosic feedstock is needed annually to achieve the power, fuel, and chemical production goals set by the Biomass Research and Development Technology Advisory Production Committee • Sustainability – Production and use of the 1 billion dry tons annually must be

  6. Finding a Roadmap to achieve Large Neuromorphic Hardware Systems

    Directory of Open Access Journals (Sweden)

    Jennifer eHasler

    2013-09-01

    Full Text Available Neuromorphic systems are gaining increasing importance in an era where CMOS digital computing techniques are meeting hard physical limits. These silicon systems mimic extremely energy efficient neural computing structures, potentially both for solving engineering applications as well as understanding neural computation. Towards this end, the authors provide a glimpse at what the technology evolution roadmap looks like for these systems so that Neuromorphic engineers may gain the same benefit of anticipation and foresight that IC designers gained from Moore's law many years ago. Scaling of energy efficiency, performance, and size will be discussed as well as how the implementation and application space of Neuromorphic systems are expected to evolve over time.

  7. Open innovation in early drug discovery: roadmaps and roadblocks.

    Science.gov (United States)

    Reichman, Melvin; Simpson, Peter B

    2016-05-01

    Open innovation in pharmaceutical R&D evolved from a triple helix of convergent paradigm shifts in academic, industrial and government research sectors. The birth of the biotechnology sector catalyzed shifts in location dynamics that led to the first wave of open innovation in pharmaceutical R&D between big pharma and startup companies. The National Institutes of Health (NIH) Roadmap was a crucial inflection point that set the stage for a new wave of open innovation models between pharmaceutical companies and universities that have the potential to transform the pharmaceutical R&D landscape. We highlight the attributes of leading protected open innovation models that foster the sharing of proprietary small molecule collections by lowering the risk of premature escape of intellectual property, particularly structure-activity data.

  8. Used fuel extended storage security and safeguards by design roadmap

    Energy Technology Data Exchange (ETDEWEB)

    Durbin, Samuel G. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Lindgren, Eric Richard [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Jones, Robert [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Ketusky, Edward [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); England, Jeffrey [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Scherer, Carolynn [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Sprinkle, James [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Miller, Michael. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Rauch, Eric [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Scaglione, John [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Dunn, T. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2016-05-01

    In the United States, spent nuclear fuel (SNF) is safely and securely stored in spent fuel pools and dry storage casks. The available capacity in spent fuel pools across the nuclear fleet has nearly reached a steady state value. The excess SNF continues to be loaded in dry storage casks. Fuel is expected to remain in dry storage for periods beyond the initial dry cask certification period of 20 years. Recent licensing renewals have approved an additional 40 years. This report identifies the current requirements and evaluation techniques associated with the safeguards and security of SNF dry cask storage. A set of knowledge gaps is identified in the current approaches. Finally, this roadmap identifies known knowledge gaps and provides a research path to deliver the tools and models needed to close the gaps and allow the optimization of the security and safeguards approaches for an interim spent fuel facility over the lifetime of the storage site.

  9. Ground-based Nuclear Detonation Detection (GNDD) Technology Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    Casey, Leslie A.

    2014-01-13

    This GNDD Technology Roadmap is intended to provide guidance to potential researchers and help management define research priorities to achieve technology advancements for ground-based nuclear explosion monitoring science being pursued by the Ground-based Nuclear Detonation Detection (GNDD) Team within the Office of Nuclear Detonation Detection in the National Nuclear Security Administration (NNSA) of the U.S. Department of Energy (DOE). Four science-based elements were selected to encompass the entire scope of nuclear monitoring research and development (R&D) necessary to facilitate breakthrough scientific results, as well as deliver impactful products. Promising future R&D is delineated including dual use associated with the Comprehensive Nuclear-Test-Ban Treaty (CTBT). Important research themes as well as associated metrics are identified along with a progression of accomplishments, represented by a selected bibliography, that are precursors to major improvements to nuclear explosion monitoring.

  10. A roadmap for the integration of culture into developmental psychopathology.

    Science.gov (United States)

    Causadias, José M

    2013-11-01

    In this paper, I propose a roadmap for the integration of culture in developmental psychopathology. This integration is pressing because culture continues to be somewhat disconnected from theory, research, training, and interventions in developmental psychopathology, thus limiting our understanding of the epigenesis of mental health. I argue that in order to successfully integrate culture into developmental psychopathology, it is crucial to (a) study cultural development, (b) consider both individual-level and social-level cultural processes, (c) examine the interplay between culture and biology, and (d) promote improved and direct cultural assessment. I provide evidence in support of each of these guidelines, present alternative conceptual frameworks, and suggest new lines of research. Hopefully, that these directions will contribute to the emerging field of cultural development and psychopathology, which focuses on the elucidation of the cultural processes that initiate, maintain, or derail trajectories of normal and abnormal behavior.

  11. Roadmap towards justice in urban climate adaptation research

    Science.gov (United States)

    Shi, Linda; Chu, Eric; Anguelovski, Isabelle; Aylett, Alexander; Debats, Jessica; Goh, Kian; Schenk, Todd; Seto, Karen C.; Dodman, David; Roberts, Debra; Roberts, J. Timmons; Vandeveer, Stacy D.

    2016-02-01

    The 2015 United Nations Climate Change Conference in Paris (COP21) highlighted the importance of cities to climate action, as well as the unjust burdens borne by the world's most disadvantaged peoples in addressing climate impacts. Few studies have documented the barriers to redressing the drivers of social vulnerability as part of urban local climate change adaptation efforts, or evaluated how emerging adaptation plans impact marginalized groups. Here, we present a roadmap to reorient research on the social dimensions of urban climate adaptation around four issues of equity and justice: (1) broadening participation in adaptation planning; (2) expanding adaptation to rapidly growing cities and those with low financial or institutional capacity; (3) adopting a multilevel and multi-scalar approach to adaptation planning; and (4) integrating justice into infrastructure and urban design processes. Responding to these empirical and theoretical research needs is the first step towards identifying pathways to more transformative adaptation policies.

  12. Structured Crowdsourcing: A B2B Innovation Roadmap

    DEFF Research Database (Denmark)

    Edgeman, Rick; Engell, Toke; Jensen, Nik Grewy

    Crowdsourcing is an increasingly popular source of both ideas and funding. Crowdsourcing in a B2B context is less well understood and, as such, much of our discussion will highlight business-to-business crowdsourcing. More generally discussion will address crowdsourcing relative to innovation...... from crowd-sourcing efforts. The roadmap emphasizes on early stages in the overall innovation management activity that is related to development and specification of the task to be crowdsourced, the identification of the crowd, the creation of the environment to connect the crowdsourcer, the task...... and the crowd, motivation of the crowd, and actual activities in reaching the crowd. Managing the input from the crowd is regarded as a later stage in the overall innovation management but also as a focal point in the arguments for improving B2B crowdsourcing. In crowd selection processes this paper aims...

  13. Evaluation of commercial lithium-ion cells based on composite positive electrode for plug-in hybrid electric vehicle applications. Part I: Initial characterizations

    Science.gov (United States)

    Dubarry, Matthieu; Truchot, Cyril; Cugnet, Mikaël; Liaw, Bor Yann; Gering, Kevin; Sazhin, Sergiy; Jamison, David; Michelbacher, Christopher

    Evaluating commercial Li-ion batteries presents some unique benefits. One of them is to use cells made from established fabrication process and form factor, such as those offered by the 18650 cylindrical configuration, to provide a common platform to investigate and understand performance deficiency and aging mechanism of target chemistry. Such an approach shall afford us to derive relevant information without influence from processing or form factor variability that may skew our understanding on cell-level issues. A series of 1.9 Ah 18650 lithium ion cells developed by a commercial source using a composite positive electrode comprising {LiMn 1/3Ni 1/3Co 1/3O 2 + LiMn 2O 4} is being used as a platform for the investigation of certain key issues, particularly path-dependent aging and degradation in future plug-in hybrid electric vehicle (PHEV) applications, under the US Department of Energy's Applied Battery Research (ABR) program. Here we report in Part I the initial characterizations of the cell performance and Part II some aspects of cell degradation in 2C cycle aging. The initial characterizations, including cell-to-cell variability, are essential for life cycle performance characterization in the second part of the report when cell-aging phenomena are discussed. Due to the composite nature of the positive electrode, the features (or signature) derived from the incremental capacity (IC) of the cell appear rather complex. In this work, the method to index the observed IC peaks is discussed. Being able to index the IC signature in details is critical for analyzing and identifying degradation mechanism later in the cycle aging study.

  14. Evaluation of commercial lithium-ion cells based on composite positive electrode for plug-in hybrid electric vehicle applications. Part I: Initial characterizations

    Energy Technology Data Exchange (ETDEWEB)

    Matthieu Dubarry; Cyril Truchot; Mikael Cugnet; Bor Yann Liaw; Kevin Gering; Sergiy Sazhin; David Jamison; Christopher Michelbacher

    2011-12-01

    Evaluating commercial Li-ion batteries presents some unique benefits. One of them is to use cells made from established fabrication process and form factor, such as those offered by the 18650 cylindrical configuration, to provide a common platform to investigate and understand performance deficiency and aging mechanism of target chemistry. Such an approach shall afford us to derive relevant information without influence from processing or form factor variability that may skew our understanding on cell-level issues. A series of 1.9 Ah 18650 lithium ion cells developed by a commercial source using a composite positive electrode comprising (LiMn1/3Ni1/3Co1/3O2 + LiMn2O4) is being used as a platform for the investigation of certain key issues, particularly path-dependent aging and degradation in future plug-in hybrid electric vehicle (PHEV) applications, under the US Department of Energy's Applied Battery Research (ABR) program. Here we report in Part I the initial characterizations of the cell performance and Part II some aspects of cell degradation in 2C cycle aging. The initial characterizations, including cell-to-cell variability, are essential for life cycle performance characterization in the second part of the report when cell-aging phenomena are discussed. Due to the composite nature of the positive electrode, the features (or signature) derived from the incremental capacity (IC) of the cell appear rather complex. In this work, the method to index the observed IC peaks is discussed. Being able to index the IC signature in details is critical for analyzing and identifying degradation mechanism later in the cycle aging study.

  15. An ESA roadmap for geobiology in space exploration

    Science.gov (United States)

    Cousins, Claire R.; Cockell, Charles S.

    2016-01-01

    Geobiology, and in particular mineral-microbe interactions, has a significant role to play in current and future space exploration. This includes the search for biosignatures in extraterrestrial environments, and the human exploration of space. Microorganisms can be exploited to advance such exploration, such as through biomining, maintenance of life-support systems, and testing of life-detection instrumentation. In view of these potential applications, a European Space Agency (ESA) Topical Team "Geobiology in Space Exploration" was developed to explore these applications, and identify research avenues to be investigated to support this endeavour. Through community workshops, a roadmap was produced, with which to define future research directions via a set of 15 recommendations spanning three key areas: Science, Technology, and Community. These roadmap recommendations identify the need for research into: (1) new terrestrial space-analogue environments; (2) community level microbial-mineral interactions; (3) response of biofilms to the space environment; (4) enzymatic and biochemical mineral interaction; (5) technical refinement of instrumentation for space-based microbiology experiments, including precursor flight tests; (6) integration of existing ground-based planetary simulation facilities; (7) integration of fieldsite biogeography with laboratory- and field-based research; (8) modification of existing planetary instruments for new geobiological investigations; (9) development of in situ sample preparation techniques; (10) miniaturisation of existing analytical methods, such as DNA sequencing technology; (11) new sensor technology to analyse chemical interaction in small volume samples; (12) development of reusable Lunar and Near Earth Object experimental platforms; (13) utility of Earth-based research to enable the realistic pursuit of extraterrestrial biosignatures; (14) terrestrial benefits and technological spin-off from existing and future space

  16. Implementation Plan for Chemical Industry R&D Roadmap for Nanomaterials by Design

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2006-04-01

    The purpose of this effort is to develop an implementation plan to realize the vision and goals identified in the Chemical Industry R&D Roadmap for Nanomaterials By Design: From Fundamentals to Function.

  17. The Soils and Groundwater – EM-20 S&T Roadmap Quality Assurance Project Plan

    Energy Technology Data Exchange (ETDEWEB)

    Fix, N. J.

    2008-02-11

    The Soils and Groundwater – EM-20 Science and Technology Roadmap Project is a U.S. Department of Energy, Office of Environmental Management-funded initiative designed to develop new methods, strategies and technology for characterizing, modeling, remediating, and monitoring soils and groundwater contaminated with metals, radionuclides, and chlorinated organics. This Quality Assurance Project Plan provides the quality assurance requirements and processes that will be followed by EM-20 Roadmap Project staff.

  18. Lean Manufacturing Implementation for Multinational Companies with Production Subsidiary in Brazil: Development of A Roadmap

    Directory of Open Access Journals (Sweden)

    L. Goehnera,

    2016-06-01

    Full Text Available Foreign multinational companies with a production subsidiary in Brazil are in general recognized as high-level productive companies; however, their productivity potential is mostly not fully achieved. Lean Manufacturing (LM has been proved as a valuable aid to achieve competitiveness in the long run. Regarding the rising importance of successfully implementing LM at multinationals in Brazil and an apparent lack of discussion regarding LM in Brazil this paper aims to propose a comprehensive implementation roadmap, which enables a multinational on a basis of a systematic approach, to achieve an advanced sustainable LM system in a practical manner. The insights of literature and case studies are combined to develop the roadmap. The roadmap was developed so that both companies, those, which have not started yet their journey towards LM, as well as those that have taken already the first steps can use the roadmap. However, the roadmap was built on a broad empirical basis. It should be noticed that it is impossible to consider all factors influencing the LMI at multinationals operating in Brazil in a real world setting. As a result, the roadmap should not be regarded as a ready implementation plan, which has to be strictly followed. Instead, it should be seen as a guideline, which helps a multinational to develop its own, detailed and fitted plan for successfully implementing LM and establishing a learning organization.

  19. Using commercial-off-the-shelf speech recognition software for conning U.S. warships

    OpenAIRE

    Tamez, Dorothy J.

    2003-01-01

    Approved for public release; distribution is unlimited The U.S. Navy's Transformation Roadmap is leading the fleet in a smaller, faster, and more technologically advanced direction. Smaller platforms and reduced manpower resources create opportunities to fill important positions, including ship-handling control, with technology. This thesis investigates the feasibility of using commercial-off-the-shelf (COTS) speech recognition software (SRS) for conning a Navy ship. Dragon NaturallySpeaki...

  20. PENGARUH EKSTRAK JAMU TERHADAP AKTIVITAS SEL NATURAL KILLER DALAM MELISIS ALUR SEL LEUKIMIA (K-562 SECARA IN VITRO [The Effects of Commercial “Jamu” Extracts on Natural Killer Cell Activity in Lysing Leukemic Cell Line (K-562 in vitro

    Directory of Open Access Journals (Sweden)

    Elisa Veronica D.C. 2

    2002-04-01

    Full Text Available Natural killer (NK cell consitutes white blood cells which specifically functions in lysing tumor and virus invected cells. In this research, a commercial “Jamu” was tested to observe its effect on NK cells activity against leukemic cell lines (K562 in vitro. Jamu was extracted with hot water, diluted and added into cell cultures consisted of a mixture of human peripheric limphocyte cells, as the source of the effector NK cells, and K562 cell line i.e., the target cells which were cell line derived from human leukemia and had been labelled with H3-thymidine. The mixture of the cells were made by culturing the two cells at the ratio of 50:1 and 100 : 1, respectively. The results showed that lysing activity of NK cells in the presence of “Jamu” water extract measured as lysing percentage and lysing index increased only slightly, which were not statiscally significant. It should be considered that the test used in this research represents only a part of the lysing mechanism by NK cells against the target cells. An in vivo test for a period of time will be recessary to elucidate ffurther this NK cell activity.

  1. Utilization of Small Commercial Grade Nickel Cadmium (NiCd) Cells in Low Earth Orbit (LEO) Applications

    OpenAIRE

    1990-01-01

    The Defense Advanced Research Projects Agency (DARPA) has sponsored the Advanced Space Technology Program (ASTP) to enhance the cost-effectiveness and responsiveness of military space systems. One of the major themes of this program is the development of highly capable small satellites, generally referred to as ''LightSats," which can perform selected defense missions at relatively low cost. A key element of the programmatic approach is the utilization of commercial grade parts and practices ...

  2. Construction of a dead-end type micro- to R.O. membrane test cell and performance test with the laboratory- made and commercial membranes

    Directory of Open Access Journals (Sweden)

    Darunee Bhongsuwan

    2002-11-01

    Full Text Available A dead-end type membrane stirred cell for an RO filtration test has been designed and constructed. Magnetic stirring system is applied to overcome a pressure-induced concentration polarization occurred over a membrane surface in the test cell. A high pressure N2 tank is used as a pressure source.Feed container is designed for 2.5 l feed solution and a stirred cell volume is 0.5 l . The test cell holds a magnetic stirrer freely moved over the membrane surface. All units are made of stainless steel. A porous SS316L disc is used as a membrane support. The dead-end stirred cell is tested to work properly in an operating pressure ranged 0 - 400 psi. It means that the dead-end cell can be used to test a membrane of different filtration modes, from micro- to Reverse Osmosis filtration. Tests performed at 400 psi for 3 hours are safe but tests at a 500 psi increase leakage possibility. The cell is used to test the performance of both commercial and laboratory-made membranes. It shows that the salt rejection efficiency of the nano- and RO membranes, NTR759HR and LES90, determined by using the new test cell, is closely similar to those reported from the manufacture. Result of the tests for our own laboratory-made membrane shows a similar performance to the nanofiltration membrane LES90.

  3. An in vitro inhibition of human malignant cell growth of crude water extract of cassava (Manihot esculenta Crantz and commercial linamarin

    Directory of Open Access Journals (Sweden)

    Nashiru Billa

    2006-03-01

    Full Text Available Epidemiological studies had shown a link between low incidences of cancer in communities where cassava intake is the main staple. The prophylactic action of cassava intake and its deleterious effect on humans are attributed mainly to the expressed toxicity of the aglycone moiety of the cyanogenic glucoside linamarin, when the latter breaks down. The effect of crude water extract of cassava leaf and that of commercial linamarin was investigated on two human tumor cell lines Caov-3 (ovarian, and HeLa (cervical adenocarcinoma in vitro, using the MTT- assay for cell growth inhibition/cytotoxicity. The effect of the enzyme linamarase (EC 3.2.1.21, a β-glucosidase also tapped from the cassava plant and treated appropriately was tested on one of the cell lines. Crude water extract or commercial linamarin was added in a final concentration of 300 µg/ml with or without the partially purified enzyme (10% added of total cell volume and culture medium to the seeded cells. The water extract was more efficacious, eliciting an IC50 value of 38 µg/ ml and 57 µg/ml, respectively, for the ovarian and cervical cell lines, while the commercial linamarin shows a growth inhibition of 150 and 210 µg/ml, respectively, for the two cell lines. Inclusion of the enzyme on a linamarin treated cervical cell line improved the growth inhibition to 40 µg/ml. The antineoplastic effect exhibited by the two samples containing the cyanogenic glucoside is explained in terms of the activity of endogenous/exogenous linamarase, presence of dietary factors in the crude extract, and a possibly induced bystander effect. Tumors are unlikely to develop any resistance against hydrocyanic acid, due to its inhibitory role in oxidative phosphorylation. Additionally, an inbuilt mechanism in vivo ensures detoxification of excess cyanide that may seep to the surrounding normal tissues. Thus properly administered by increasing the prodrug concentration at the tumor site and decreasing its

  4. Electrochemistry of the Zinc-Silver Oxide System. Part 2: Practical Measurements of Energy Conversion Using Commercial Miniature Cells.

    Science.gov (United States)

    Smith, Michael J.; Vincent, Colin A.

    1989-01-01

    Summarizes the quantitative relationships pertaining to the operation of electrochemical cells. Energy conversion efficiency, cycle efficiency, battery power, and energy/power density of two types of zinc-silver oxide cells are discussed. (YP)

  5. Effect of commercial enzymes on berry cell wall deconstruction in the context of intravineyard ripeness variation under winemaking conditions

    DEFF Research Database (Denmark)

    Gao, Yu; Fangel, Jonatan Ulrik; Willats, William George Tycho;

    2016-01-01

    at the berry cell wall polymer level and occurred within the experimental vineyard block. Furthemore, all enzyme treatments reduced cell wall variation via depectination. Interestingly, cell wall esterification levels were unaffected by enzyme treatments. This study provides clear evidence that enzymes can...

  6. Towards 15% energy conversion efficiency: a systematic study of the solution-processed organic tandem solar cells based on commercially available materials

    DEFF Research Database (Denmark)

    Li, Ning; Baran, Derya; Forberich, Karen

    2013-01-01

    in organic tandem solar cells. All the devices are processed under environmental conditions using doctor-blading, which is highly compatible with mass-production coating technologies. Power conversion efficiencies (PCE) of 6–7% are obtained for OPV devices based on different active layers. Optical...... simulations based on experimental data are performed for all realized tandem solar cells. An efficiency potential of ∼10% is estimated for these compounds in combination with phenyl-C61-butyric acid methyl ester (PCBM) as an acceptor. In addition, we assume a hypothetical, optimized acceptor to understand...... the limitation of donors. It is suggested that a PCE of >14% is realistic for tandem solar cells based on these commercially available donor materials. Along with the demonstration of novel intermediate layers we believe that this systematic study provides valuable insight for those attempting to realize...

  7. Strategic Roadmap for the Development of an Interstellar Space Program

    Science.gov (United States)

    Gifra, M.; Peeters, W.

    Recent technological advances and scientific discoveries, particularly in astronomy and space technology, are opening our minds into the deepest realms of the universe, and also they are bringing a new era of space exploration and development. This sense of entering into a new era of space exploration is being boosted by the permanent discovery of new planets - to date, there are 684 confirmed extrasolar planets [1] - outside our solar system. The possibility that astronomers may soon find a habitable extrasolar planet near Earth and the recent advances in space propulsion that could reduce travel times have stimulated the space community to consider the development of an interstellar manned mission. But this scenario of entering into a new era of space development is ultimately contingent on the outcome of the actual world's economic crisis. The current financial crisis, on top of recent national and sovereign debts problems, could have serious consequences for space exploration and development as the national budgets for space activities are to freeze [2].This paper proposes a multi-decade space program for an interstellar manned mission. It designs a roadmap for the achievement of interstellar flight capability within a timeframe of 40 years, and also considers different scenarios where various technological and economical constraints are taken into account in order to know if such a space endeavour could be viable. It combines macro-level scenarios with a strategic roadmap to provide a framework for condensing all information in one map and timeframe, thus linking decision-making with plausible scenarios. The paper also explores the state of the art of space technologies 20 to 40 years in the future and its potential economic impact. It estimates the funding requirements, possible sources of funds, and the potential returns.The Interstellar Space Program proposed in this paper has the potential to help solve the global crisis by bringing a new landscape of

  8. Roadmap for Nondestructive Evaluation of Reactor Pressure Vessel Research and Development by the Light Water Reactor Sustainability Program

    Energy Technology Data Exchange (ETDEWEB)

    Smith, Cyrus M [ORNL; Nanstad, Randy K [ORNL; Clayton, Dwight A [ORNL; Matlack, Katie [Georgia Institute of Technology; Ramuhalli, Pradeep [Pacific Northwest National Laboratory (PNNL); Light, Glenn [Southwest Research Institute, San Antonio

    2012-09-01

    The Department of Energy s (DOE) Light Water Reactor Sustainability (LWRS) Program is a five year effort which works to develop the fundamental scientific basis to understand, predict, and measure changes in materials and systems, structure, and components as they age in environments associated with continued long-term operations of existing commercial nuclear power reactors. This year, the Materials Aging and Degradation (MAaD) Pathway of this program has placed emphasis on emerging Non-Destructive Evaluation (NDE) methods which support these objectives. DOE funded Research and Development (R&D) on emerging NDE techniques to support commercial nuclear reactor sustainability is expected to begin next year. This summer, the MAaD Pathway invited subject matter experts to participate in a series of workshops which developed the basis for the research plan of these DOE R&D NDE activities. This document presents the results of one of these workshops which are the DOE LWRS NDE R&D Roadmap for Reactor Pressure Vessels (RPV). These workshops made a substantial effort to coordinate the DOE NDE R&D with that already underway or planned by the Electric Power Research Institute (EPRI) and the Nuclear Regulatory Commission (NRC) through their representation at these workshops.

  9. Enteroscopy and radiology for the management of celiac disease complications: Time for a pragmatic roadmap.

    Science.gov (United States)

    Branchi, Federica; Locatelli, Martina; Tomba, Carolina; Conte, Dario; Ferretti, Francesca; Elli, Luca

    2016-06-01

    Celiac disease is the most common autoimmune enteropathy in Western countries, and is usually associated with a good response to the gluten free diet and an excellent prognosis. However, a minority of patients develop complications of the disease, such as refractory celiac disease, ulcerative jejunoileitis and neoplastic complications such as adenocarcinoma of the small bowel and enteropathy associated T cell lymphoma. Neoplastic complications described in association with celiac disease have a high mortality rate, due to their aggressive behavior and to the usual advanced stage at the time of diagnosis. In recent years, the detection of small bowel lesions has dramatically improved thank to the availability of highly performing radiologic and endoscopic techniques. The diagnostic delay of malignant complications in patients with celiac disease may be improved by establishing a pragmatic flowchart for the identification and follow up of "at risk" patients. We performed a comprehensive review of the articles published on this issue in order to promote a roadmap to be applied when facing with celiac patients with suspected small bowel complications.

  10. Trends in robotics: A summary of the Department of Energy`s critical technology roadmap

    Energy Technology Data Exchange (ETDEWEB)

    Eicker, P.J.

    1998-08-10

    Technology roadmaps serve as pathways to the future. They call attention to future needs for research and development; provide a structure for organizing technology forecasts and programs; and help communicate technological needs and expectations among end users and the research and development (R and D) community. Critical Technology roadmaps, of which the Robotics and Intelligent Machines (RIM) Roadmap is one example, focus on enabling or cross-cutting technologies that address the needs of multiple US Department of Energy (DOE) offices. Critical Technology roadmaps must be responsive to mission needs of the offices; must clearly indicate how the science and technology can improve DOE capabilities; and must describe an aggressive vision for the future of the technology itself. The RIM Roadmap defines a DOE research and development path for the period beginning today, and continuing through the year 2020. Its purpose is to identify, select and develop objectives that will satisfy near- and long-term challenges posed by DOE`s mission objectives. If implemented, this roadmap will support DOE`s mission needs while simultaneously advancing the state-of-the-art of RIM. For the purposes of this document, RIM refers to systems composed of machines, sensors, computers and software that deliver processes to DOE operations. The RIM Roadmap describes how such systems will revolutionize DOE processes, most notably manufacturing, hazardous and remote operations, and monitoring and surveillance. The advances in DOE operations and RIM discussed in this document will be possible due to the developments in many other areas of science and technology, including computing, communication, electronics and micro-engineering. Modern software engineering techniques will permit the implementation of inherently safe RIM systems that will depend heavily on software.

  11. Transistor roadmap projection using predictive full-band atomistic modeling

    Energy Technology Data Exchange (ETDEWEB)

    Salmani-Jelodar, M., E-mail: m.salmani@gmail.com; Klimeck, G. [Network for Computational Nanotechnology and School of Electrical and Computer Engineering, Purdue University, West Lafayette, Indiana 47907 (United States); Kim, S. [Intel Corporation, 2501 Northwest 229th Avenue, Hillsboro, Oregon 97124 (United States); Ng, K. [Semiconductor Research Corporation (SRC), 1101 Slater Rd, Durham, North Carolina 27703 (United States)

    2014-08-25

    In this letter, a full band atomistic quantum transport tool is used to predict the performance of double gate metal-oxide-semiconductor field-effect transistors (MOSFETs) over the next 15 years for International Technology Roadmap for Semiconductors (ITRS). As MOSFET channel lengths scale below 20 nm, the number of atoms in the device cross-sections becomes finite. At this scale, quantum mechanical effects play an important role in determining the device characteristics. These quantum effects can be captured with the quantum transport tool. Critical results show the ON-current degradation as a result of geometry scaling, which is in contrast to previous ITRS compact model calculations. Geometric scaling has significant effects on the ON-current by increasing source-to-drain (S/D) tunneling and altering the electronic band structure. By shortening the device gate length from 20 nm to 5.1 nm, the ratio of S/D tunneling current to the overall subthreshold OFF-current increases from 18% to 98%. Despite this ON-current degradation by scaling, the intrinsic device speed is projected to increase at a rate of at least 8% per year as a result of the reduction of the quantum capacitance.

  12. Roadmap for sustainable water resources in southwestern North America.

    Science.gov (United States)

    Gleick, Peter H

    2010-12-14

    The management of water resources in arid and semiarid areas has long been a challenge, from ancient Mesopotamia to the modern southwestern United States. As our understanding of the hydrological and climatological cycles has improved, and our ability to manipulate the hydrologic cycle has increased, so too have the challenges associated with managing a limited natural resource for a growing population. Modern civilization has made remarkable progress in water management in the past few centuries. Burgeoning cities now survive in desert regions, relying on a mix of simple and complex technologies and management systems to bring adequate water and remove wastewater. These systems have permitted agricultural production and urban concentrations to expand in regions previously thought to have inadequate moisture. However, evidence is also mounting that our current management and use of water is unsustainable. Physical, economic, and ecological limits constrain the development of new supplies and additional water withdrawals, even in regions not previously thought vulnerable to water constraints. New kinds of limits are forcing water managers and policy makers to rethink previous assumptions about population, technology, regional planning, and forms of development. In addition, new threats, especially the challenges posed by climatic changes, are now apparent. Sustainably managing and using water in arid and semiarid regions such as the southwestern United States will require new thinking about water in an interdisciplinary and integrated way. The good news is that a wide range of options suggest a roadmap for sustainable water management and use in the coming decades.

  13. Modeling Influenza Virus Infection: A Roadmap for Influenza Research

    Directory of Open Access Journals (Sweden)

    Alessandro Boianelli

    2015-10-01

    Full Text Available Influenza A virus (IAV infection represents a global threat causing seasonal outbreaks and pandemics. Additionally, secondary bacterial infections, caused mainly by Streptococcus pneumoniae, are one of the main complications and responsible for the enhanced morbidity and mortality associated with IAV infections. In spite of the significant advances in our knowledge of IAV infections, holistic comprehension of the interplay between IAV and the host immune response (IR remains largely fragmented. During the last decade, mathematical modeling has been instrumental to explain and quantify IAV dynamics. In this paper, we review not only the state of the art of mathematical models of IAV infection but also the methodologies exploited for parameter estimation. We focus on the adaptive IR control of IAV infection and the possible mechanisms that could promote a secondary bacterial coinfection. To exemplify IAV dynamics and identifiability issues, a mathematical model to explain the interactions between adaptive IR and IAV infection is considered. Furthermore, in this paper we propose a roadmap for future influenza research. The development of a mathematical modeling framework with a secondary bacterial coinfection, immunosenescence, host genetic factors and responsiveness to vaccination will be pivotal to advance IAV infection understanding and treatment optimization.

  14. Quo Vadis Venomics? A Roadmap to Neglected Venomous Invertebrates

    Directory of Open Access Journals (Sweden)

    Bjoern Marcus von Reumont

    2014-12-01

    Full Text Available Venomics research is being revolutionized by the increased use of sensitive -omics techniques to identify venom toxins and their transcripts in both well studied and neglected venomous taxa. The study of neglected venomous taxa is necessary both for understanding the full diversity of venom systems that have evolved in the animal kingdom, and to robustly answer fundamental questions about the biology and evolution of venoms without the distorting effect that can result from the current bias introduced by some heavily studied taxa. In this review we draw the outlines of a roadmap into the diversity of poorly studied and understood venomous and putatively venomous invertebrates, which together represent tens of thousands of unique venoms. The main groups we discuss are crustaceans, flies, centipedes, non-spider and non-scorpion arachnids, annelids, molluscs, platyhelminths, nemerteans, and echinoderms. We review what is known about the morphology of the venom systems in these groups, the composition of their venoms, and the bioactivities of the venoms to provide researchers with an entry into a large and scattered literature. We conclude with a short discussion of some important methodological aspects that have come to light with the recent use of new -omics techniques in the study of venoms.

  15. ROAMER: roadmap for mental health research in Europe.

    Science.gov (United States)

    Haro, Josep Maria; Ayuso-Mateos, José Luis; Bitter, Istvan; Demotes-Mainard, Jacques; Leboyer, Marion; Lewis, Shôn W; Linszen, Donald; Maj, Mario; McDaid, David; Meyer-Lindenberg, Andreas; Robbins, Trevor W; Schumann, Gunter; Thornicroft, Graham; Van Der Feltz-Cornelis, Christina; Van Os, Jim; Wahlbeck, Kristian; Wittchen, Hans-Ulrich; Wykes, Til; Arango, Celso; Bickenbach, Jerome; Brunn, Matthias; Cammarata, Pamela; Chevreul, Karine; Evans-Lacko, Sara; Finocchiaro, Carla; Fiorillo, Andrea; Forsman, Anna K; Hazo, Jean-Baptiste; Knappe, Susanne; Kuepper, Rebecca; Luciano, Mario; Miret, Marta; Obradors-Tarragó, Carla; Pagano, Grazia; Papp, Szilvia; Walker-Tilley, Tom

    2014-01-01

    Despite the high impact of mental disorders in society, European mental health research is at a critical situation with a relatively low level of funding, and few advances been achieved during the last decade. The development of coordinated research policies and integrated research networks in mental health is lagging behind other disciplines in Europe, resulting in lower degree of cooperation and scientific impact. To reduce more efficiently the burden of mental disorders in Europe, a concerted new research agenda is necessary. The ROAMER (Roadmap for Mental Health Research in Europe) project, funded under the European Commission's Seventh Framework Programme, aims to develop a comprehensive and integrated mental health research agenda within the perspective of the European Union (EU) Horizon 2020 programme, with a translational goal, covering basic, clinical and public health research. ROAMER covers six major domains: infrastructures and capacity building, biomedicine, psychological research and treatments, social and economic issues, public health and well-being. Within each of them, state-of-the-art and strength, weakness and gap analyses were conducted before building consensus on future research priorities. The process is inclusive and participatory, incorporating a wide diversity of European expert researchers as well as the views of service users, carers, professionals and policy and funding institutions.

  16. [Ethical aspects of human embryonic stem cell use and commercial umbilical cord blood stem cell banking. Ethical reflections on the occasion of the regulation of the European Council and Parliament on advanced therapy medicinal products].

    Science.gov (United States)

    Virt, G

    2010-01-01

    The regulation of the European Council and Parliament on advanced therapy medicinal products also includes therapies with human embryonic stem cells. The use of these stem cells is controversially and heavily discussed. Contrary to the use of adult stem cells, medical and ethical problems concerning the use of human embryonic stem cells persists, because this use is based on the destruction of human life at the very beginning. The regulation foresees, therefore, subsidiarity within the European Member States. Although there are no ethical problems in principle with the use of stem cells from the umbilical cord blood, there are social ethical doubts with the banking of these stem cells for autologous use without any currently foreseeable medical advantage by commercial blood banks. Also in this case subsidiarity is valid.

  17. Chemical and electronic interface structure of spray pyrolysis deposited undoped and Al-doped ZnO thin films on a commercial Cz-Si solar cell substrate

    Energy Technology Data Exchange (ETDEWEB)

    Gabas, M.; Ramos-Barrado, J.R. [Dpto. de Fisica Aplicada I, Lab. de Materiales y Superficies, Universidad de Malaga 29071 Malaga (Spain); Barrett, N.T. [CEA DSM/IRAMIS/SPCSI, CEA Saclay, 91191 Gif sur Yvette (France); Gota, S. [Laboratoire Leon Brillouin, UMR 012 CEA-CNRS CEA Saclay, 91191 Gif sur Yvette (France); Rojas, T.C. [Instituto de Ciencia de Materiales de Sevilla, CSIC, Americo Vespucio 49, 41092 Sevilla (Spain); Lopez-Escalante, M.C. [Isofoton S.A., Parque Tecnologico de Andalucia, Severo Ochoa, 50, 29590 Malaga (Spain)

    2009-08-15

    We have studied differences in the interface between undoped and Al-doped ZnO thin films deposited on commercial Si solar cell substrates. The undoped ZnO film is significantly thicker than the Al-doped film for the same deposition time. An extended silicate-like interface is present in both samples. Transmission electron microscopy (TEM) and photoelectron spectroscopy (PES) probe the presence of a zinc silicate and several Si oxides in both cases. Although Al doping improves the conductivity of ZnO, we present evidence for Al segregation at the interface during deposition on the Si substrate and suggest the presence of considerable fixed charge near the oxidized Si interface layer. The induced distortion in the valence band, compared to that of undoped ZnO, could be responsible for considerable reduction in the solar cell performance. (author)

  18. Rate-dependent, Li-ion insertion/deinsertion behavior of LiFePO4 cathodes in commercial 18650 LiFePO4 cells.

    Science.gov (United States)

    Liu, Qi; He, Hao; Li, Zhe-Fei; Liu, Yadong; Ren, Yang; Lu, Wenquan; Lu, Jun; Stach, Eric A; Xie, Jian

    2014-03-12

    We have performed operando synchrotron high-energy X-ray diffraction (XRD) to obtain nonintrusive, real-time monitoring of the dynamic chemical and structural changes in commercial 18650 LiFePO4/C cells under realistic cycling conditions. The results indicate a nonequilibrium lithium insertion and extraction in the LiFePO4 cathode, with neither the LiFePO4 phase nor the FePO4 phase maintaining a static composition during lithium insertion/extraction. On the basis of our observations, we propose that the LiFePO4 cathode simultaneously experiences both a two-phase reaction mechanism and a dual-phase solid-solution reaction mechanism over the entire range of the flat voltage plateau, with this dual-phase solid-solution behavior being strongly dependent on charge/discharge rates. The proposed dual-phase solid-solution mechanism may explain the remarkable rate capability of LiFePO4 in commercial cells.

  19. Introduction and Analysis of Synthetic Biology Roadmap of the UK%英国合成生物学路线图

    Institute of Scientific and Technical Information of China (English)

    李振兴

    2013-01-01

    英国高度重视发展合成生物学,并将合成生物学作为可能引领未来经济发展的4个新兴技术产业之一,不仅对合成生物学研究予以大力支持,也致力于促进合成生物学研究和技术的商业化。为谋求在合成生物学领域世界领先地位,英国商业、创新与技能部专门成立了英国合成生物学路线图协调组,开展路线图研究,制定并发布了英国合成生物学路线图研究报告。对英国最新发布的英国合成生物学路线图从发展合成生物学的重要意义、英国谋求引领未来合成生物学发展地位、路线图研究框架和制定过程、路线图涉及的主题及促进合成生物学发展的措施等5个方面进行了解析,以期为我国开展有关政策研究和确定发展重点提供参考。%Synthetic biology is one of the four priorities of emerging technologies and industries in the UK. UK has made a lot of investment on both scientific research of synthetic biology and its commercialization. Recently, the Department of Business, Innovation and Skill (BIS) set up a special group to draw up the roadmap of synthetic biology in the UK. In this paper, the main contents of the roadmap were introduced and analyzed from ifve aspects in order to contribute to the policy study and priorities selection of synthetic biology in China. The ifve aspects are as follows:the importance of developing synthetic biology;UK’s target of leading the global synthetic biology;research framework and making process of roadmap;themes concerning the roadmap;measures to prompt development of synthetic biology.

  20. SUPPLIER SELECTION STRATEGY AND MANUFACTURING FLEXIBILITY: IMPACT OF QUALITY AND TECHNOLOGY ROADMAPS

    Directory of Open Access Journals (Sweden)

    Muhamad Jantan

    2006-01-01

    Full Text Available The study evaluates the relationship between technology, quality, cost and delivery performance-based, supplier selection strategies, and manufacturing flexibilities namely, product flexibility, launch flexibility, and volume flexibility. Moreover, the moderating impact of supplier management strategies, namely quality roadmap and technology roadmap on the above relationships were also explored. The data for the study was drawn from a sample of companies listed in the factory directory published by the Penang Development Corporation (PDC. A postal survey of 120 manufacturers provided a return of 92 usable responses. The results reveal that the selection of suppliers based on technological and quality performance positively affects all the three dimensions of manufacturing flexibility, with complementary effects of good technology and quality roadmaps. Technology and quality roadmaps act as predictors for product and volume flexibilities. However, when launch flexibility is the focus, both technology and quality roadmaps moderate the impact of supplier selection strategies. Details of the findings, theoretical and practical implications, and the research limitation are discussed.

  1. Strategic Program Planning Lessons Learned In Developing The Long-Term Stewardship Science and Technology Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    Dixon, B.W.; Hanson, D.J.; Matthern, G.E.

    2003-04-24

    Technology roadmapping is a strategic planning method used by companies to identify and plan the development of technologies necessary for new products. The U.S. Department of Energy's Office of Environmental Management has used this same method to refine requirements and identify knowledge and tools needed for completion of defined missions. This paper describes the process of applying roadmapping to clarify mission requirements and identify enhancing technologies for the Long-Term Stewardship (LTS) of polluted sites after site cleanup has been completed. The nature of some contamination problems is such that full cleanup is not achievable with current technologies and some residual hazards remain. LTS maintains engineered contaminant barriers and land use restriction controls, and monitors residual contaminants until they no longer pose a risk to the public or the environment. Roadmapping was used to clarify the breadth of the LTS mission, to identify capability enhancements needed to improve mission effectiveness and efficiency, and to chart out the research and development efforts to provide those enhancements. This paper is a case study of the application of roadmapping for program planning and technical risk management. Differences between the planned and actual application of the roadmapping process are presented along with lessons learned. Both the process used and lessons learned should be of interest for anyone contemplating a similar technology based planning effort.

  2. Strategic Program Planning Lessons Learned in Developing the LTS S&T Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    Duane Hanson; Brent Dixon; Gretchen Matthern

    2003-07-01

    Technology roadmapping is a strategic planning method used by companies to identify and plan the development of technologies necessary for new products. The U.S. Department of Energy’s Office of Environmental Management has used this same method to refine requirements and identify knowledge and tools needed for completion of defined missions. This paper describes the process of applying roadmapping to clarify mission requirements and identify enhancing technologies for the Long-Term Stewardship (LTS) of polluted sites after site cleanup has been completed. The nature of some contamination problems is such that full cleanup is not achievable with current technologies and some residual hazards remain. LTS maintains engineered contaminant barriers and land use restriction controls, and monitors residual contaminants until they no longer pose a risk to the public or the environment. Roadmapping was used to clarify the breadth of the LTS mission, to identify capability enhancements needed to improve mission effectiveness and efficiency, and to chart out the research and development efforts to provide those enhancements. This paper is a case study of the application of roadmapping for program planning and technical risk management. Differences between the planned and actual application of the roadmapping process are presented along with lessons learned. Both the process used and lessons learned should be of interest for anyone contemplating a similar technology based planning effort.

  3. Energy Technology Roadmaps: A Guide to Development and Implementation. 2014 edition

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2014-03-01

    New low-carbon technologies show clear potential for transforming the global energy system, but a key challenge remains: what steps do governments and industry need to take to ensure their development and deployment? Roadmapping, used for decades in technology-intensive industries, is a useful tool to help address complicated issues strategically at the national, regional and global levels. To help turn political statements and analytical work into concrete action, the International Energy Agency (IEA) is developing a series of global roadmaps devoted to low-carbon energy technologies. Drawing upon the extensive IEA experience, this guide is aimed at providing countries and companies with the context, information and tools needed to design, manage and implement an effective energy technology roadmap process relevant to their own local circumstances and objectives. This edition of the Energy Technology Roadmaps: a guide to development and implementation includes more detailed guidance on how to identify key stakeholders, develop a technology baseline and development of indicators to help track progress against roadmap milestones. The IEA hopes that this guide and the examples and references it offers, together with the new IEA How2Guides, which provide technology-specific guidance, will help national and local policy makers and industry to develop strategies that accelerate the deployment of low-carbon energy technologies worldwide.

  4. The Advanced Modeling, Simulation and Analysis Capability Roadmap Vision for Engineering

    Science.gov (United States)

    Zang, Thomas; Lieber, Mike; Norton, Charles; Fucik, Karen

    2006-01-01

    This paper summarizes a subset of the Advanced Modeling Simulation and Analysis (AMSA) Capability Roadmap that was developed for NASA in 2005. The AMSA Capability Roadmap Team was chartered to "To identify what is needed to enhance NASA's capabilities to produce leading-edge exploration and science missions by improving engineering system development, operations, and science understanding through broad application of advanced modeling, simulation and analysis techniques." The AMSA roadmap stressed the need for integration, not just within the science, engineering and operations domains themselves, but also across these domains. Here we discuss the roadmap element pertaining to integration within the engineering domain, with a particular focus on implications for future observatory missions. The AMSA products supporting the system engineering function are mission information, bounds on information quality, and system validation guidance. The Engineering roadmap element contains 5 sub-elements: (1) Large-Scale Systems Models, (2) Anomalous Behavior Models, (3) advanced Uncertainty Models, (4) Virtual Testing Models, and (5) space-based Robotics Manufacture and Servicing Models.

  5. Transition Management: Case Study of an Energy Efficiency Technology Roadmap in Turkey

    Directory of Open Access Journals (Sweden)

    Şiir Kilkiş

    2014-12-01

    Full Text Available This paper integrates several streams of literature in transition management and proposes a holistic framework for its application in policy-making. Separate fields of study, such as motors of change and strategic intelligence tools, are unified in a single analytical process. The process involves five steps that may be repeated until a desired policy objective is achieved. The pilot, integrated technology roadmap process that has been launched in Turkey is analyzed as a case study. The Energy Efficiency Technology Roadmap has been completed with the participation of over 160 experts in 5 different stages. It involved the collection of over 349 Delfi statements, their consolidation for a Delfi survey with 16 statements, the analysis of the results, a focal group meeting to develop roadmaps for the 7 selected goals, and the consultation of the roadmaps to the sector. The paper concludes that an integrated technology roadmap process, as described in the pilot case study, provides an advanced version of transition management, which is needed to mobilize research, development, and innovation for sustainable development.

  6. Research and Development Roadmap for Water Heating Technologies

    Energy Technology Data Exchange (ETDEWEB)

    Goetzler, William [Navigant Consulting Inc.; Gagne, Claire [Navigant Consulting Inc.; Baxter, Van D [ORNL; Lutz, James [Lawrence Berkeley National Laboratory (LBNL); Merrigan, Tim [National Renewable Energy Laboratory (NREL); Katipamula, Srinivas [Pacific Northwest National Laboratory (PNNL)

    2011-10-01

    Although water heating is an important energy end-use in residential and commercial buildings, efficiency improvements in recent years have been relatively modest. However, significant advancements related to higher efficiency equipment, as well as improved distribution systems, are now viable. DOE support for water heating research, development and demonstration (RD&D) could provide the impetus for commercialization of these advancements.

  7. Assessment of the cytotoxic, genotoxic and mutagenic effects of the commercial black dye in Allium cepa cells before and after bacterial biodegradation treatment.

    Science.gov (United States)

    Ventura-Camargo, Bruna de Campos; de Angelis, Dejanira de Franceschi; Marin-Morales, Maria Aparecida

    2016-10-01

    The present study evaluated the cytotoxic, genotoxic and mutagenic actions of different concentrations (50 and 200 μg/L) of BDCP (Black Dye Commercial Product) used by textile industries, before and after bacterial biodegradation, by the conventional staining cytogenetic technique and NOR-banding in Allium cepa cells. Differences in the chromosomal and nuclear aberrations and alterations in the number of nucleoli were observed in cells exposed to BDCP with and without the microbial treatment. The significant frequencies of chromosome and nuclear aberrations noted in the tests with bacterially biodegraded BDCP indicate that the metabolites generated by degradation are more genotoxic than the chemical itself. Losses of genetic material characterize a type of alteration that was mainly associated with the action of the original BDCP, whereas chromosome stickiness, nuclear buds and binucleated cells were the aberrations that were preferentially induced by BDCP metabolites after biodegradation. The significant frequencies of cell death observed in the tests with biodegraded BDCP also show the cytotoxic effects of the BDCP metabolites. The reduction in the total frequency of altered cells after the recovery treatments showed that the test organism A. cepa has the ability to recover from damage induced by BDCP and its metabolites after the exposure conditions are normalized.

  8. The effect of charging rate on the graphite electrode of commercial lithium-ion cells: A post-mortem study

    Science.gov (United States)

    Somerville, L.; Bareño, J.; Trask, S.; Jennings, P.; McGordon, A.; Lyness, C.; Bloom, I.

    2016-12-01

    Increased charging rates negatively affect the lifetime of lithium-ion cells by increasing cell resistance and reducing capacity. This work is a post-mortem study of 18650-type cells subjected to charge rates of 0.7-, 2-, 4-, and 6-C. For cells charged at 0.7-C to 4-C, this performance degradation is primarily related to surface film thickness with no observable change in surface film chemical composition. However, at charge rates of 6-C, the chemical composition of the surface film changes significantly, suggesting that this change is the reason for the sharper increase in cell resistance compared to the lower charge rates. In addition, we found that surface film formation was not uniform across the electrode. Surface film was thicker and chemically different along the central band of the electrode "jelly roll". This result is most likely attributable to an increase in temperature that results from non-uniform electrode wetting during manufacture. This non-uniform change further resulted in active material delamination from the current collector owing to chemical changes to the binder for the cell charged at 6-C.

  9. Evaluation of the antioxidant capacity, furan compounds and cytoprotective/cytotoxic effects upon Caco-2 cells of commercial Colombian coffee.

    Science.gov (United States)

    Bedoya-Ramírez, Daniel; Cilla, Antonio; Contreras-Calderón, José; Alegría-Torán, Amparo

    2017-03-15

    Antioxidant capacity (AC), total phenolics (TPs), furan compounds (HMF and furfural F) and cytoprotective/cytotoxic effects upon Caco-2 cells (MTT, cell cycle and reactive oxygen species (ROS)) were evaluated in Colombian coffee (2 ground and 4 soluble samples). The AC (ABTS and FRAP), TPs and HMF ranged between 124-722, 95-802μmoles Trolox/g, 21-100mg gallic acid/g and 69-2900mg/kg, respectively. Pretreatment of cells for 24h with lyophilized coffee infusions at the highest dose without cytotoxic effects (500μg/mL) significantly prevented the decrease in cell viability compared to control stress with H2O2 (5mM/2h), recovering viability to values between 34% and 45% and restoring the control values without stress induction in the G1 phase of cell cycle. After exposure to stress, four extracts decreased ROS values significantly to 22.5-24.9%. The coffee samples exerted a cytoprotective effect against oxidative stress, with improvement in cell viability and a reduction of intracellular ROS.

  10. The NASA Electronic Parts and Packaging (NEPP) Program: Roadmap for FY15 and Beyond and Recent Radiation Highlights

    Science.gov (United States)

    LaBel, Kenneth A.; Sampson, Michael J.

    2015-01-01

    This presentation is a NASA Electronic Parts and Packaging (NEPP) Program: Roadmap for FY15 and Beyond. This roadmap provides a snapshot for current plans and collaborations on testing and evaluation of electronics as well as a discussion of the technology selection approach.

  11. Space agencies' scientific roadmaps need harmonisation and reegular re-assessment

    Science.gov (United States)

    Worms, Jean-Claude; Culhane, J. Leonard; Walter, Nicolas; Swings, Jean-Pierre; Detsis, Emmanouil

    The need to consider international collaboration in the exploration of space has been recognised since the dawn of the space age in 1957. Since then, international collaboration has been the main operational working mode amongst space scientists the world over, setting aside national pre-eminence and other political arguments. COSPAR itself was created as a tool for scientists to maintain the dialogue at the time of the cold war. Similarly the inherent constraints of the field (cost, complexity, time span) have led space agencies to try and coordinate their efforts. As a result many - if not all - of the key space science missions since the 60’s have been collaborative by nature. Different collaboration models have existed with varying success, and the corresponding lessons learned have been assessed through various fora and reports. For various reasons whose scope has broadened since that time (use of space in other domains such as Earth observation, telecommunication and navigation; emergence of commercial space activities; increased public appeal and capacity to motivate the young generation to engage into related careers), the importance of international collaboration in space has never faltered and coordination among spacefaring nations has become the norm. However programme harmonisation is often found to be lacking, and duplication of efforts sometimes happens due to different planning and decision procedures, programmatic timelines or budgetary constraints. Previous studies, in particular by the European ESSC-ESF, with input from the US NAS-SSB, advocated the need to establish a coordinating body involving major space agencies to address these coordination issues in a systematic and harmonious way. Since then and in line with this recommendation, the International Space Exploration Coordination Group (ISECG) of 14 space agencies was created in 2007 and published a first roadmap to advance a “Global Exploration Strategy”. ISECG is non-binding though

  12. Investigation of path dependence in commercial lithium-ion cells for pure electric bus applications: Aging mechanism identification

    Science.gov (United States)

    Ma, Zeyu; Jiang, Jiuchun; Shi, Wei; Zhang, Weige; Mi, Chunting Chris

    2015-01-01

    There is a growing need to provide more realistic and accurate State of Health estimations for batteries in electric vehicles. Thus, it is necessary to research various lithium-ion cell aging processes, including cell degradation and related path dependence. This paper focuses on quantitative analyses of cell aging path dependence in a repeatable laboratory setting, considering the influence of duty cycles, depth of discharge (DOD), and the frequency and severity of the thermal cycle, as reflected in pure electric buses operated in Beijing. Incremental capacity analysis (ICA) and differential voltage analysis (DVA) are applied to infer cell degradation mechanisms and quantify the attributions to capacity fade. It was observed that the cells experienced a higher rate of aging at 80% DOD and an accelerated aging at 40 °C in the thermal cycling, as a result of possible loss of active material (LAM) in both electrodes, in addition to the loss of lithium inventory (LLI) and inhibited kinetics. The slight capacity fade from low-temperature extremes likely caused by LLI due to lithium plating, whereas the noticeable fade after the high-temperature excursion was likely caused by LAM and hindrance to kinetics. These results may lead to improved battery management in EV applications.

  13. A covenant of halflings? developing a roadmap for the european urban transport goal

    DEFF Research Database (Denmark)

    Gudmundsson, Henrik; Schippl, Jens; Anderton, Karen

    2015-01-01

    In the 2011 Transport Policy White Paper, the European Commission introduced ten goals for a more competitive and resource efficient transport system. One of the goal concerns urban transport, with the dual targets: “To halve the use of ‘conventionally-fuelled’ cars in urban transport by 2030......; and to phase them out by 2050; and “To achieve ‘essentially CO2- free city logistics’ in major urban centres by 2030.” This paper describes how the EU FP7 project TRANSFORUM conducted a stakeholder-driven process to produce a roadmap for the urban transport goal. A main conclusion was that the implementation...... of a roadmap for urban transport needs to adopt a broad and open approach, given the diversity among member states and cities across Europe. Also it was found that replacing conventional vehicles and fuels is an important but not sufficient strategy to reach the goal. A roadmap to reach towards the ‘halving...

  14. Roadmaps for the Development of Technologies Related to Danish Wave Power Systems

    DEFF Research Database (Denmark)

    Nielsen, Kim; Krogh, Jan; Brodersen, H. J.

    2015-01-01

    The Danish Partnership for Wave Power was established in 2011 under the project "New strategy for wave power through industrial partnership" [1] funded by the Danish Energy Technology Development and Demonstration Program. The core of this partnership is nine active Danish wave energy developers...... seconded by offshore industry, and research institutions. The Danish Partnership for Wave Power has further been consolidated through the follow-on Roadmap project described in this paper. The roadmap project has in detail investigated how the four most common technology areas for wave power developers can...... activities (research, development and test) are necessary to achieve the desired level of technology i.e. in 2020. The Roadmaps can thus be used to prioritize and coordinate technology development projects....

  15. Windows and Building Envelope Research and Development: A Roadmap for Emerging Technologies

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2014-02-01

    This Building Technologies Office (BTO) Research and Development (R&D) Roadmap identifies priority windows and building envelope R&D areas of interest. Cost and performance targets are identified for each key R&D area. The roadmap describes the technical and market challenges to be overcome, R&D activities and milestones, key stakeholders, and potential energy savings that could result if cost and performance targets are met. Methods for improving technology performance and specific strategies for reducing installed costs and mitigating any other market barriers, which would increase the likelihood of mass-market technology adoption, are identified. This roadmap is a useful resource for public and private decision makers evaluating and pursuing high-impact R&D focused on advancing next-generation energy efficient windows and building envelope technologies.

  16. Fluoride Salt-Cooled High-Temperature Reactor Technology Development and Demonstration Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    Holcomb, David Eugene [ORNL; Flanagan, George F [ORNL; Mays, Gary T [ORNL; Pointer, William David [ORNL; Robb, Kevin R [ORNL; Yoder Jr, Graydon L [ORNL

    2013-11-01

    Fluoride salt-cooled High-temperature Reactors (FHRs) are an emerging reactor class with potentially advantageous performance characteristics, and fully passive safety. This roadmap describes the principal remaining FHR technology challenges and the development path needed to address the challenges. This roadmap also provides an integrated overview of the current status of the broad set of technologies necessary to design, evaluate, license, construct, operate, and maintain FHRs. First-generation FHRs will not require any technology breakthroughs, but do require significant concept development, system integration, and technology maturation. FHRs are currently entering early phase engineering development. As such, this roadmap is not as technically detailed or specific as would be the case for a more mature reactor class. The higher cost of fuel and coolant, the lack of an approved licensing framework, the lack of qualified, salt-compatible structural materials, and the potential for tritium release into the environment are the most obvious issues that remain to be resolved.

  17. Novel method to characterize CYP21A2 in Florida patients with congenital adrenal hyperplasia and commercially available cell lines

    Directory of Open Access Journals (Sweden)

    Christopher N. Greene

    2014-01-01

    Full Text Available Congenital adrenal hyperplasia (CAH is an autosomal recessive disorder and affects approximately 1 in 15,000 births in the United States. CAH is one of the disorders included on the Newborn Screening (NBS Recommended Uniform Screening Panel. The commonly used immunological NBS test is associated with a high false positive rate and there is interest in developing second-tier assays to increase screening specificity. Approximately 90% of the classic forms of CAH, salt-wasting and simple virilizing, are due to mutations in the CYP21A2 gene. These include single nucleotide changes, insertions, deletions, as well as chimeric genes involving CYP21A2 and its highly homologous pseudogene CYP21A1P. A novel loci-specific PCR approach was developed to individually amplify the CYP21A2 gene, the nearby CYP21A1P pseudogene, as well as any 30 kb deletion and gene conversion mutations, if present, as single separate amplicons. Using commercially available CAH positive specimens and 14 families with an affected CAH proband, the single long-range amplicon approach demonstrated higher specificity as compared to previously published methods.

  18. ROADIDEA- Roadmap for radical innovations in European transport services

    Science.gov (United States)

    Saarikivi, P.

    2009-09-01

    Weather plays a key role in most traffic accidents, in which over 40.000 European citizens are killed and more than 1,2 million injured every year. It is thus clear that innovations are needed to develop better road weather services to make traffic safer. As transport is responsible of 20% of green house gas emissions in Europe, such services are also needed that make traffic more efficient and reduce congestion. ROADIDEA "Roadmap for radical innovations in European transport services” is a FP7/INFSO Collaboration project that started in 2007 and continues until mid-2010, see www.roadidea.eu. The main objective is to study the potential of the European transport service sector for innovations, analysing available data sources, revealing existing problems and bottlenecks, and developing better methods and models to be utilised in service platforms. These will be capable of providing new, innovative services for various transport user groups. The fourteen partners of ROADIDEA come from Finland, Sweden, the Netherlands, Germany, Italy, Hungary, Croatia and Slovenia. The differences of the existing transport systems and available data sources in these countries are analysed as well as the problems caused by local climate and geography. The innovation process is key activity of the project and will be described in detail in the presentation. It has produced more than 100 ideas during two consecutive brainstorming seminars. Ideas have been analysed and the most potential ones shortlisted for further development. These include e.g. advanced friction models, road condition and fog warning systems, which receive input from hybrid (mobile and fixed combined) observing systems and automated messages from private cars. The Hamburg Port with increasing congestion needs multi-modal traffic model that takes weather into account. New semi-public high-quality ways to travel need to be innovated to reduce the use of private cars in the battle against climate change.

  19. A physiome interoperability roadmap for personalized drug development.

    Science.gov (United States)

    Thomas, Simon; Wolstencroft, Katherine; de Bono, Bernard; Hunter, Peter J

    2016-04-06

    The goal of developing therapies and dosage regimes for characterized subgroups of the general population can be facilitated by the use of simulation models able to incorporate information about inter-individual variability in drug disposition (pharmacokinetics), toxicity and response effect (pharmacodynamics). Such observed variability can have multiple causes at various scales, ranging from gross anatomical differences to differences in genome sequence. Relevant data for many of these aspects, particularly related to molecular assays (known as '-omics'), are available in online resources, but identification and assignment to appropriate model variables and parameters is a significant bottleneck in the model development process. Through its efforts to standardize annotation with consequent increase in data usability, the human physiome project has a vital role in improving productivity in model development and, thus, the development of personalized therapy regimes. Here, we review the current status of personalized medicine in clinical practice, outline some of the challenges that must be overcome in order to expand its applicability, and discuss the relevance of personalized medicine to the more widespread challenges being faced in drug discovery and development. We then review some of (i) the key data resources available for use in model development and (ii) the potential areas where advances made within the physiome modelling community could contribute to physiologically based pharmacokinetic and physiologically based pharmacokinetic/pharmacodynamic modelling in support of personalized drug development. We conclude by proposing a roadmap to further guide the physiome community in its on-going efforts to improve data usability, and integration with modelling efforts in the support of personalized medicine development.

  20. Synthesizing R&D Data: Experiences from the Integrated Manufacturing Technology Roadmap (IMTR) Project

    Energy Technology Data Exchange (ETDEWEB)

    merrell, m.a.

    1999-05-05

    IMTR is a tremendous undertaking to assess the current state and future needs of Manufacturing Technology R&D. A follow-on project to the roadmaps is the development and populating of a Gap Analysis database containing current R&D abstracts related to the roadmaps' technical elements. Efficiently identifying the R&D projects within scope presents many travails of synthesizing data from across a wide spectrum. Challenges to this project were directly proportional to the lack of single-source data collections.

  1. a Roadmap to Advance Understanding of the Science of Space Weather

    Science.gov (United States)

    Schrijver, K.; Kauristie, K.; Aylward, A.; De Nardin, C. M.; Gibson, S. E.; Glover, A.; Gopalswamy, N.; Grande, M.; Hapgood, M. A.; Heynderickx, D.; Jakowski, N.; Kalegaev, V. V.; Lapenta, G.; Linker, J.; Liu, S.; Mandrini, C. H.; Mann, I. R.; Nagatsuma, T.; Nandy, D.; Obara, T.; O'Brien, T. P., III; Onsager, T. G.; Opgenoorth, H. J.; Terkildsen, M. B.; Valladares, C. E.; Vilmer, N.

    2015-12-01

    There is a growing appreciation that the environmental conditions that we call space weather impact the technological infrastructure that powers the coupled economies around the world. With that comes the need to better shield society against space weather by improving forecasts, environmental specifications, and infrastructure design. A COSPAR/ILWS team recently completed a roadmap that identifies the scientific focus areas and research infrastructure that are needed to significantly advance our understanding of space weather of all intensities and of its implications and costs for society. This presentation provides a summary of the highest-priority recommendations from that roadmap.

  2. Towards nZEB - Some Examples of National Requirements and Roadmaps

    DEFF Research Database (Denmark)

    Jagemar, Lennart; Schmidt, Michael; Allard, Francis;

    2011-01-01

    A recent benchmarking study on implementation on EPBD 2002 by REHVA (Seppänen & Goeders 2010) revealed a large variation in the energy performance regulations of the different countries. Not only the performance levels are different, but even the units, in which the performance is measured...... in the definition of energy performance in [kWh/m2,a]. Many countries have prepared long term roadmaps with detailed targets, Figure 1. Such roadmaps help the industry to be prepared and committed to the targets. For example, in Norway, zero energy buildings are expected in 2027, but in UK carbon neutral buildings...

  3. Research and Development Roadmap For Next-Generation Low-Global Warming Potential Refrigerants

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2011-07-01

    The Department of Energy commissioned this roadmap to establish a set of high-priority research and development (R&D) activities that will accelerate the transition to low-GWP refrigerants across the entire heating, ventilation, air-conditioning and refrigeration (HVAC&R) industry. The schedule of R&D activities occurs within an accelerated five-year timeframe, and covers several prominent equipment types. The roadmap is organized around four primary objectives to: assess and mitigate safety risks, characterize refrigerant properties, understand efficiency and environmental tradeoffs, and support new refrigerant and equipment development.

  4. Fabrication of lanthanum strontium cobalt ferrite (LSCF) cathodes for high performance solid oxide fuel cells using a low price commercial inkjet printer

    Science.gov (United States)

    Han, Gwon Deok; Neoh, Ke Chean; Bae, Kiho; Choi, Hyung Jong; Park, Suk Won; Son, Ji-Won; Shim, Joon Hyung

    2016-02-01

    In this study, we investigate a method to fabricate high quality lanthanum strontium cobalt ferrite (LSCF) cathodes for solid oxide fuel cells (SOFCs) using a commercial low price inkjet printer. The ink source is synthesized by dissolving the LSCF nanopowder in a water-based solvent with a proper amount of surfactants. Microstructures of the LSCF layer, including porosity and thickness per printing scan cycle, are adjusted by grayscale in the printing image. It is successfully demonstrated that anode-supported SOFCs with optimally printed LSCF cathodes can produce decent power output, i.e., a maximum peak power density of 377 mW cm-2 at 600 °C, in our experiment. We expect that this approach can support the quick and easy prototyping and evaluating of a variety of cathode materials in SOFC research.

  5. Comparison of commercial RNA extraction kits for preparation of DNA-free total RNA from Salmonella cells

    Directory of Open Access Journals (Sweden)

    Gonzalez-Escalona Narjol

    2010-07-01

    Full Text Available Abstract Background The isolation of DNA-free RNA is a crucial step in the reverse transcription PCR (RT-PCR. Every RNA extraction procedure results in RNA samples contaminated with genomic DNA, which can cause false-positive outcomes in highly sensitive applications, including a recently developed quantitative real-time PCR (RT-qPCR assay that targets invA mRNA for the detection of live Salmonella cells. The assay of this specific mRNA can be used to indicate the presence of live, as opposed to dead, cells of Salmonella enterica in a food matrix. Findings We evaluated the ability of five RNA extraction kits to produce RNA preparations from exponentially growing Salmonella cells. The acceptability of the preparations for use in downstream applications such as RT-qPCR was judged in terms of the total amount of RNA recovered, the integrity of the RNA molecules, and minimal content of DNA. The five kits produced RNA preparations that differed markedly in yield, integrity of the Salmonella RNA and the amount of contaminant DNA. The greatest RNA recovery was achieved with the MasterPure kit; however, the preparation contained high levels of genomic DNA. The UltraClean extraction kit gave a low level of RNA recovery with a poor level of integrity. The RNeasy Mini, RiboPure and PureLink extraction kits produced high-quality, DNA-free RNA suitable for Salmonella detection by RT-qPCR. Conclusions We showed that the RNeasy Mini and PureLink RNA extraction kits were the most suitable for the detection of Salmonella invA mRNA by RT-qPCR. The use of these two kits will greatly reduce the frequency of false-positive results and might allow fast RT-qPCR determination of invA mRNA produced by viable Salmonella in food samples.

  6. Commercializing light-duty plug-in/plug-out hydrogen-fuel-cell vehicles: "Mobile electricity" technologies, early California household markets, and innovation management

    Science.gov (United States)

    Williams, Brett David

    Starting from the premise that new consumer value must drive hydrogen-fuel-cell-vehicle (H2FCV) commercialization, a group of opportunities collectively called "Mobile Electricity" (Me-) is characterized. Me- redefines H2 FCVs as innovative products able to provide home recharging and mobile power, for example for tools, mobile activities, emergencies, and electric-grid-support services. To characterize such opportunities, this study first integrates and extends previous analyses of H2FCVs, plug-in hybrids, and vehicle-to-grid (V2G) power. It uses a new model to estimate zero-emission-power vs. zero-emission-driving tradeoffs, costs, and grid-support revenues for various electric-drive vehicle types and levels of infrastructure service. Next, the initial market potential for Me- enabled vehicles, such as H2FCVs and plug-in hybrids, is estimated by eliminating unlikely households from consideration for early adoption. 5.2 million of 33.9 million Californians in the 2000 Census live in households pre-adapted to Me-, 3.9 million if natural gas is required for home refueling. The possible sales base represented by this population is discussed. Several differences in demographic and other characteristics between the target market and the population as a whole are highlighted, and two issues related to the design of H2FCVs and their supporting infrastructure are discussed: vehicle range and home hydrogen refueling. These findings argue for continued investigation of this and similar target segments-which represent more efficient research populations for subsequent study by product designers and other decision-makers wishing to understand the early market dynamics facing Me- innovations. Next, Me-H2FCV commercialization issues are raised from the perspectives of innovation, product development, and strategic marketing. Starting with today's internalcombustion hybrids, this discussion suggests a way to move beyond the battery vs. fuel-cell zero-sum game and towards the

  7. Highly-Exposed HIV-1 seronegative Female Commercial Sex Workers sustain in their genital mucosa increased frequencies of tolerogenic myeloid and regulatory T-cells

    Science.gov (United States)

    Thibodeau, V.; Fourcade, L.; Labbé, A.-C.; Alary, M.; Guédou, F.; Poudrier, J.; Roger, M.

    2017-01-01

    We and others have shown that HIV-1 highly-exposed seronegative (HESN) female commercial sex workers (CSWs) maintain low genital inflammatory conditions to prevent HIV infection. HIV-1 interacts with toll-like receptors (TLR)-7/8 to induce interferon (IFN)-α, an important antiviral and immunomodulatory cytokine, which act together with interleukin (IL)-10, human leukocyte antigen (HLA)-G and immunoglobulin-like transcript (ILT)-4 to initiate a “tolerogenic/regulatory” anti-inflammatory loop. In view of further unravelling elements associated with natural immunity to HIV-1, we have characterised TLR-7, IFN-α, IL-10, HLA-G and ILT-4 expression profiles in the genital tract of female CSWs and HIV-1-uninfected non-CSWs from Benin. Endocervical myeloid HLA-DR+ cells from HESN CSWs expressed higher levels of IFN-α, TLR-7, IL-10 and HLA-G than those from both HIV-1-infected CSWs and HIV-1-uninfected non-CSWs. Further characterization of the endocervical myeloid HLA-DR+ cells in HESN CSWs revealed a population of “tolerogenic” CD103+ CD14+ CD11c+ myeloid cells expressing high levels of IFN-α and IL-10. Concomitantly, HESN CSWs had higher frequencies of endocervical regulatory CD4+ T-cells when compared to those from the two other groups of women. These novel findings provide strong evidence to support the implication of tolerogenic myeloid cells expressing high levels of antiviral molecules in shaping the genital mucosal immune response to prevent HIV infection. PMID:28262752

  8. Effects of the nanotopographic surface structure of commercially pure titanium following anodization–hydrothermal treatment on gene expression and adhesion in gingival epithelial cells

    Energy Technology Data Exchange (ETDEWEB)

    Takebe, J., E-mail: takebej@iwate-med.ac.jp; Miyata, K.; Miura, S.; Ito, S.

    2014-09-01

    The long-term stability and maintenance of endosseous implants with anodized–hydrothermally treated commercially pure titanium surfaces and a nanotopographic structure (SA-treated c.p.Ti) depend on the barrier function provided by the interface between the transmucosal portion of the implant surface and the peri-implant epithelium. This study investigated the effects of extracellular and intracellular gene expression in adherent gingival epithelial cells cultured for 1–7 days on SA-treated c.p.Ti implant surfaces compared to anodic oxide (AO) c.p.Ti and c.p.Ti disks. Scanning electron microscopy (SEM) showed filopodium-like extensions bound closely to the nanotopographic structure of SA-treated c.p.Ti at day 7 of culture. Gene expressions of focal adhesion kinase, integrin-α6β4, and laminin-5 (α3, β3, γ2) were significantly higher on SA-treated c.p.Ti than on c.p.Ti or AO c.p.Ti after 7 days (P < 0.05). Our results confirmed that gingival epithelial cells adhere to SA-treated c.p.Ti as the transmucosal portion of an implant, and that this interaction markedly improves expression of focal adhesion molecules and enhances the epithelial cell phenotype. The cellular gene expression responses driving extracellular and intracellular molecular interactions thus play an important role in maintenance at the interface between SA-treated c.p.Ti implant surfaces and the gingival epithelial cells. - Highlights: • SA-treated Ti provides a nanotopographic structure for clinical oral implants. • This could regulate integrin-mediated epithelial cell adhesion and gene expression. • FAK mRNA was significantly higher on SA-treated Ti. • Integrin-α6β4 and laminin-5 mRNA were significantly higher on SA-treated Ti. • Extracellular/intracellular molecular interactions play a key role on SA-treated Ti.

  9. Effectively Improved SiO2-TiO2 Composite Films Applied in Commercial Multicrystalline Silicon Solar Cells

    Directory of Open Access Journals (Sweden)

    Chih-Hsiang Yang

    2013-01-01

    Full Text Available Composite silicon dioxide-titanium dioxide (SiO2-TiO2 films are deposited on a large area of 15.6 × 15.6 cm2 textured multicrystalline silicon solar cells to increase the incident light trapped within the device. For further improvement of the antireflective coatings (ARCs quality, dimethylformamide (DMF solution is added to the original SiO2-TiO2 solutions. DMF solution solves the cracking problem, thus effectively decreasing reflectance as well as surface recombination. The ARCs prepared by sol-gel process and plasma-enhanced chemical vapor deposition (PECVD on multicrystalline silicon substrate are compared. The average efficiency of the devices with improved sol-gel ARCs is 16.3%, only 0.5% lower than that of devices with PECVD ARCs (16.8%. However, from equipment depreciation point of view (the expiration date of equipment is generally considered as 5 years, the running cost (USD/watt of sol-gel technique is 80% lower than that of PECVD method for the first five years and 66% lower than that of PECVD method from the start of the sixth year. This result proves that sol-gel-deposited ARCs process has potential applications in manufacturing low-cost, large-area solar cells.

  10. Optimization of Rear Local Al-Contacts on High Efficiency Commercial PERC Solar Cells with Dot and Line Openings

    Directory of Open Access Journals (Sweden)

    Peisheng Liu

    2014-01-01

    Full Text Available Crystalline silicon PERCs with dot or line openings on rear surface were studied here. By measuring the minor carrier lifetimes of the PERCs with dot and line openings, passivation effects of rear surface with dot and line openings were discussed. The performance affected by dot and line openings was analyzed in detail by testing the open-circuit voltages, short-circuit current densities, fill factors, and conversion efficiencies of the PERCs. The results show that the wider space resulted in better minor carrier lifetimes on the rear surface. And the cells with a line opening space of 0.5 mm had an average of 0.22% improvement of conversion efficiency, compared with the cells with full-area Al-BSF. On the other hand, the dot opening PERCs exhibited only a conversion efficiency of 17.4%, although there had been good rear surface reflectivity. The bad Al-Si alloy layer and large hollow densities in dot Al-contacts resulted in bad performance of the PERCs with dot openings.

  11. Novel low-cost approach for removal of surface contamination before texturization of commercial monocrystalline silicon solar cells

    Energy Technology Data Exchange (ETDEWEB)

    Gangopadhyay, U. [Electronics and Telecommunication Engineering Department, IC Design and Fabrication Centre, Jadavpur University, Kolkata 700032 (India); School of Information and Communication Engineering, Sungkyunkwan University, 300, Chun-Chun dong, Jangan-gu, Suwon, 440-746 (Korea); Dhungel, S.K.; Yi, J. [School of Information and Communication Engineering, Sungkyunkwan University, 300, Chun-Chun dong, Jangan-gu, Suwon, 440-746 (Korea); Mondal, A.K. [Department of Chemistry, Bengal Engineering and Science University, Shibpur, Howrah 71103 (India); Saha, H. [Electronics and Telecommunication Engineering Department, IC Design and Fabrication Centre, Jadavpur University, Kolkata 700032 (India)

    2007-07-23

    This paper reports a novel approach on the surface treatment of monocrystalline silicon solar cells using an inorganic chemical, sodium hypochlorite (NaOCl) that has some remarkable properties. The treatment of contaminated crystalline silicon wafer with hot NaOCl helps the removal of organic contaminants due to its oxidizing properties. The objective of this paper is to establish the effectiveness of this treatment using hot NaOCl solution before the saw damage removal step of the conventional NaOH texturing approach. A comparative study of surface morphology and FTIR analyses of textured monocrystalline silicon surfaces with and without NaOCl pre-treatment is also reported. The process could result in a significant low cost approach viable for cleaning silicon wafers on a mass production scale. (author)

  12. Roadmap for human resources for expanded Indian nuclear industry

    Energy Technology Data Exchange (ETDEWEB)

    Singh, R.K. [Bhabha Atomic Research Centre, Mumbai (India); Indian Nuclear Society (India); Srinivasan, G.R.; Goyal, O.P. [Bhabha Atomic Research Centre, Mumbai (India)

    2011-07-01

    This paper deals with detailed requirement of human resources for all phases of nuclear power plant, for the manufacturing sector and the probable roadmap for achieving India's target. The accident in Fukushima has brought out that only nuclear power that avoids being a threat to the health and safety of the population and the environmental will be acceptable to the society and for this to be achieved human resources could be a single major contributor. India has ambitious plan of achieving 20,000MW by 2020 and 63,000MW by 2050. It is felt out of the three resources men, material and money; the critical shortage would be human resources both in quality and quantity. As per IAEA report (Publication of 2008 edition of energy, electricity and nuclear power estimates for the period of 2030), nuclear capacity must grow to at least 1.8 times current capacity by 2030 if global temperature rises are to be kept at 2°C. Objective of recruiting and training human resources for Indian Industry can be as follows: a) For catering domestic market. b) For catering international market later on for nuclear industries outside India. As India will be an important future international player. The above would require a multiplication of human resources by nearly seven times. In addition it has to be wholesome covering all levels and all skills and all disciplines and stages covering the whole nuclear cycle including regulators. Human resources are required for design and engineering, construction, commissioning, operation, manufacturing and for support services. The manpower for these has to be trained to achieve high quality of nuclear standards. Presently Indian Department of Atomic Energy(DAE) runs several training schools giving one year Post Graduate, tailor made courses. This needs to be multiplied by Joint efforts. Training should be on 'SAT (Systematic Approach to Training)' methodology to ensure focussed, specific, needed to culminate in safe, reliable and

  13. European roadmap to the realization of fusion energy: Mission for solution on heat-exhaust systems

    NARCIS (Netherlands)

    Turnyanskiy, M.; Neu, R.; Albanese, R.; Ambrosino, R.; Bachmann, C.; Brezinsek, S.; Donne, A. J. H.; Eich, T.; Falchetto, G.; G Federici,; Kalupin, D.; Litaudon, X.; Mayoral, M.; McDonald, D. C.; Reimerdes, H.; Romanelli, F.; Wenninger, R.; You, J. H.

    2015-01-01

    Horizon 2020 is the largest EU Research and Innovation programme to date. The European fusion research programme for Horizon 2020 is outlined in the “Roadmap to the realization of fusion energy” and published in 2012 [1]. As part of it, the European Fusion Consortium (EUROfusion) has been establishe

  14. NASA strategic roadmap: origin, evolution, structure, and density of the universe

    Science.gov (United States)

    White, Nicholas E.

    2005-08-01

    The NASA strategic roadmap on the Origin, Evolution, Structure and Destiny of the Universe is one of 13 roadmaps that outline NASA's approach to implement the vision for space exploration. The roadmap outlines a program to address the questions: What powered the Big Bang? What happens close to a Black Hole? What is Dark Energy? How did the infant universe grow into the galaxies, stars and planets, and set the stage for life? The roadmap builds upon the currently operating and successful missions such as HST, Chandra and Spitzer. The program contains two elements, Beyond Einstein and Pathways to Life, performed in three phases (2005-2015, 2015-2025 and >2025) with priorities set by inputs received from reviews undertaken by the National Academy of Sciences and technology readiness. The program includes the following missions: 2005-2015 GLAST, JWST and LISA; 2015-2025 Constellation-X and a series of Einstein Probes; and >2025 a number of ambitious vision missions which will be prioritized by results from the previous two phases.

  15. The European Hematology Association Roadmap for European Hematology Research : a consensus document

    NARCIS (Netherlands)

    Engert, Andreas; Balduini, Carlo; Brand, Anneke; Coiffier, Bertrand; Cordonnier, Catherine; Döhner, Hartmut; de Wit, Thom Duyvené; Eichinger, Sabine; Fibbe, Willem; Green, Tony; de Haas, Fleur; Iolascon, Achille; Jaffredo, Thierry; Rodeghiero, Francesco; Salles, Gilles; Schuringa, Jan Jacob

    2016-01-01

    The European Hematology Association (EHA) Roadmap for European Hematology Research highlights major achievements in diagnosis and treatment of blood disorders and identifies the greatest unmet clinical and scientific needs in those areas to enable better funded, more focused European hematology rese

  16. Rehabilitation robotics in robotics for healthcare ; a roadmap study for the European Commission

    NARCIS (Netherlands)

    Gelderblom, G.J.; Wilt, M.de; Cremers, G.; Rensma, A.R.

    2009-01-01

    To gain understanding in the current status of Robotics in healthcare the European Commission issued a roadmap study into this domain. This paper reports on the main characteristics and results of this study. The study covered the wide domain of Healthcare and in this paper the domains relevant for

  17. RESET Roadmap for European research on Smartcard rElated Technologies

    NARCIS (Netherlands)

    Gras, F.; Le Dantec, B.; Trebucq, O.; Cucinelli, B; Leduc, M.; Simplot, D.; Bueker, U.; Barthe, G.; Michaud, B.; Hartel, P.H.; Thevenot, B.; Moedl, A.; Quisquater, J.J.; Thomasson, J.P.; Canto, E.

    2003-01-01

    The objective of RESET (Roadmap for European research on Smartcard related Technologies) is to investigate the RTD needs corresponding to current and expected future technology gaps, identified by the industry and resulting from market and product trends foreseen by smart card industrial players. Th

  18. Internal Consistency in Components of International Management/International Business Syllabi: Roadmaps with Mixed Messages

    Science.gov (United States)

    Veliyath, Rajaram; Adams, Janet S.

    2005-01-01

    The course syllabus is a contract between instructor and students, a schedule of course assignments and activities, and a roadmap delineating objectives and checkpoints in the course. It is also a planning and reference tool for both students and instructor, and it models professors' expectations for their students. This study investigated whether…

  19. Assistive Robotics in Robotics for healthcare, roadmap study for the EC

    NARCIS (Netherlands)

    Gelderblom, G.J.; Wilt, M. de; Cremers, G.; Rensma, A.

    2009-01-01

    To gain understanding in the current status of Robotics in healthcare the European Commission issued a roadmap study into this domain. This paper reports on the main characteristics and results of this study. The study covered the wide domain of Healthcare and in this paper the domains relevant for

  20. Regional Open Innovation Roadmapping: A New Framework for Innovation-Based Regional Development

    Directory of Open Access Journals (Sweden)

    Wim Schwerdtner

    2015-02-01

    Full Text Available To foster sustainable regional development, many regions rely on innovations. To safeguard the generation of innovations and their market introduction, companies have increasingly used technology roadmapping and open innovation. The project INNOrural (Innovations for sustainable rural development expanded these concepts by applying them to regions. This led to the rise of the “Regional Open Innovation Roadmapping” framework for innovation-based regional development (ROIR. This framework was tested by conducting two innovation roadmapping processes in the model region of Märkisch-Oderland (MOL, Germany: the certification of regional wood fuel and the establishment of a competence center for precision farming technology. Both innovation ideas were selected during the roadmapping process by applying a sustainability assessment. After 12 months, two complete roadmaps were ready for implementation. Key principles of ROIR were identified, including the use of a clear and replicable sustainability assessment method, the involvement of all relevant stakeholder groups in the early process and the cooperation between regional and subject experts. Generally, the broader adaptation of ROIR for additional regions will be useful. Nevertheless, the ROIR processes need to be evaluated in depth to develop a better understanding and to provide evidence of the benefits and limitations of this approach.

  1. Sustainable Electronic Roadmap and Forum Summary; Sustainable Electronics Forum, October 15-18, 2012, Racine, WI

    Science.gov (United States)

    The Roadmap presents critical issues and research questions for each theme. For Theme 1, the issues for limiting the harm from materials and process in electronics industry include identifying the chemicals in products, production process, in the extraction of virgin materials, i...

  2. A roadmap for the EU White Paper goal on Urben Transport

    DEFF Research Database (Denmark)

    Gudmundsson, Henrik; Schippl, Jens; Leiren, Merethe Dotterud;

    2015-01-01

    policy options, the diverse interests of stakeholders involved in urban mobility in Europe. The paper draws on data gathered in the EU FP7 TRANSFORuM project, including workshop dialogues with stakeholders representing different interests in and perspectives on urban transport and mobility. The main...... and the outcomes of the roadmap process and will also discuss the perspectives for implementation....

  3. NASA Strategic Roadmap: Origin, Evolution, Structure, and Destiny of the Universe

    Science.gov (United States)

    White, Nicholas E.

    2005-01-01

    The NASA strategic roadmap on the Origin, Evolution, Structure and Destiny of the Universe is one of 13 roadmaps that outline NASA s approach to implement the vision for space exploration. The roadmap outlines a program to address the questions: What powered the Big Bang? What happens close to a Black Hole? What is Dark Energy? How did the infant universe grow into the galaxies, stars and planets, and set the stage for life? The roadmap builds upon the currently operating and successful missions such as HST, Chandra and Spitzer. The program contains two elements, Beyond Einstein and Pathways to Life, performed in three phases (2005-2015, 2015-2025 and >2025) with priorities set by inputs received from reviews undertaken by the National Academy of Sciences and technology readiness. The program includes the following missions: 2005-2015 GLAST, JWST and LISA; 2015-2025 Constellation-X and a series of Einstein Probes; and >2025 a number of ambitious vision missions which will be prioritized by results from the previous two phases.

  4. The european hematology association roadmap for european hematology research: A consensus document

    NARCIS (Netherlands)

    A. Engert (Andreas); C.L. Balduini (Carlo); A. Brand (Anneke); B. Coiffier (B.); C. Cordonnier (Charlotte); H. Döhner (Hartmut); De Wit, T.D. (Thom Duyvené); Eichinger, S. (Sabine); W.E. Fibbe (Willem); Green, T. (Tony); De Haas, F. (Fleur); A. Iolascon (Achille); T. Jaffredo (Thierry); Rodeghiero, F. (Francesco); Sall Es, G. (Gilles); J.J. Schuringa; J.-L. André (Jean-Luc); I. André-Schmutz (Isabelle); A. Bacigalupo; P-Y. Bochud (Pierre-Yves); M.L. den Boer (Monique); C. Bonini (Chiara); C. Camaschella (Clara); A. Cant (Andrew); M.D. Cappellini (Maria); M. Cazzola; Celso, C.L. (Cristina Lo); M.A. Dimopoulos (Meletios); Douay, L. (Luc); E.A. Dzierzak (Elaine); H. Einsele (Hermann); A.J.M. Ferreri (Andrés J.M.); De Franceschi, L. (Lucia); Gaulard, P. (Philippe); B. Göttgens (Berthold); A. Greinacher (Andreas); P. Gresele (Paolo); J. Gribben (John); De Haan, G. (Gerald); Hansen, J.-B. (John-Bjarne); A. Hochhaus (Andreas); Kadir, R. (Rezan); S.V. Kaveri (Srini); Kouskoff, V. (Valerie); Kühne, T. (Thomas); Kyrle, P. (Paul); P. Ljungman; Maschmeyer, G. (Georg); S. Mendez-Ferrer (S.); Milsom, M. (Michael); Mummery, C. (Christine); G.J. Ossenkoppele (Gert); A. Pecci (Alessandro); F. Peyvandi (Flora); J.N.J. Philipsen (Sjaak); P.H. Reitsma; J.M. Ribera (Josep Maria); Risitano, A. (Antonio); Rivella, S. (Stefano); W. Ruf (Wolfram); Schroeder, T. (Timm); Scully, M. (Marie); G. Socie (Gerard); F.J.T. Staal (Frank); S. Stanworth (Simon); Stauder, R. (Reinhard); S. Stilgenbauer (S.); Tamary, H. (Hannah); K. Theilgaard-Mönch (K.); Thein, S.L. (Swee Lay); H. Tilly (Herve); M. Trneny (Marek); Vainchenker, W. (William); A.M. Vannucchi (Alessandro); Viscoli, C. (Claudio); Vrielink, H. (Hans); Zaaijer, H. (Hans); Zanella, A. (Alberto); Zolla, L. (Lello); J.J. Zwaginga (Jaap); Martinez, P.A. (Patricia Aguilar); E. van den Akker (Eric); Allard, S. (Shubha); N.P. Anagnou (Nicholas); Andolfo, I. (Immacolata); Andrau, J.-C. (Jean-Christophe); Angelucci, E. (Emanuele); D.J. Anstee (David J.); Aurer, I. (Igor); H. Avet-Loiseau (Hervé); Y. Aydinok (Yesim); Bakchoul, T. (Tamam); Balduini, A. (Alessandra); Barcellini, W. (Wilma); Baruch, D. (Dominique); Baruchel, A. (André); J. Bayry (Jagadeesh); Bento, C. (Celeste); A. van den Berg (Anemone); Bernardi, R. (Rosa); Bianchi, P. (Paola); A. Bigas (Anna); A. Biondi (Andrea); Bohonek, M. (Milos); Bonnet, D. (Dominique); Borchmann, P. (Peter); Borregaard, N. (Niels); Brækkan, S. (Sigrid); M.R.M. Van Den Brink (Marcel R. M.); Brodin, E. (Ellen); L. Bullinger (Lars); C. Buske (Christian); Butzeck, B. (Barbara); J. Cammenga (Jörg); G. Campo (Gianluca); I. Carbone; Cervantes, F. (Francisco); S. Cesaro; P. Charbord (Pierre); F.H.J. Claas (Frans); Cohen, H. (Hannah); Conard, J. (Jacqueline); Coppo, P. (Paul); Vives Corron, J.-L. (Joan-Lluis); Da Costa, L. (Lydie); Davi, F. (Frederic); H.R. Delwel (Ruud); Dianzani, I. (Irma); Domanović, D. (Dragoslav); Donnelly, P. (Peter); Drnovšek, T.D. (Tadeja Dovč); M. Dreyling (Martin); Du, M.-Q. (Ming-Qing); Dufour, C. (Carlo); C. Durand (Charles); Efremov, D. (Dimitar); A. Eleftheriou (Androulla); Elion, J. (Jacques); M. Emonts (Marieke); M. Engelhardt (Monika); Ezine, S. (Sophie); J.H.F. Falkenburg (Frederik); Favier, R. (Remi); M. Federico (M.); P. Fenaux (Pierre); J. Fitzgibbon (Jude); Flygare, J. (Johan); R. Foà; L. Forrester (Lesley); Galacteros, F. (Frederic); Garagiola, I. (Isabella); C. Gardiner (Chris); Garraud, O. (Olivier); Van Geet, C. (Christel); H. Geiger (Hartmut); J. Geissler (Jan); U. Germing (Ulrich); Ghevaert, C. (Cedric); D. Girelli (Domenico); Godeau, B. (Bertrand); Gökbuget, N. (Nicola); H. Goldschmidt (Hartmut); A.C. Goodeve; T. Graf (Thomas); Graziadei, G. (Giovanna); Griesshammer, M. (Martin); Gruel, Y. (Yves); F. Guilhot (François); Von Gunten, S. (Stephan); I.C. Gyssens (Inge); J.P. Halter (Joerg P.); C.N. Harrison (Claire N.); C.L. Harteveld (Cornelis); Hellström-Lindberg, E. (Eva); Hermine, O. (Olivier); Higgs, D. (Douglas); Hillmen, P. (Peter); Hirsch, H. (Hans); Hoskin, P. (Peter); G. Huls (Gerwin); Inati, A. (Adlette); Johnson, P. (Peter); Kattamis, A. (Antonis); Kiefel, V. (Volker); M. Kleanthous (Marina); Klump, H. (Hannes); Krause, D. (Daniela); Hovinga, J.K. (Johanna Kremer); Lacaud, G. (Georges); Lacroix-Desmazes, S. (Sébastien); Landman-Parker, J. (Judith); Legouill, S. (Steven); Lenz, G. (Georg); M. Von Lilienfeld-Toal (Marie); M.M. von Lindern (Marieke); Lopez-Guillermo, A. (Armando); Lopriore, E. (Enrico); Lozano, M. (Miguel); E. Macintyre; M. Makris (M.); Mannhalter, C. (Christine); J.H.A. Martens (Joost); S. Mathas (Stephan); Matzdorff, A. (Axel); A. Medvinsky (Alexander); Menendez, P. (Pablo); G. Migliaccio (Giovanni); Miharada, K. (Kenichi); Mikulska, M. (Malgorzata); V. Minard (Véronique); Montalbán, C. (Carlos); De Montalembert, M. (Mariane); E. Montserrat (Emili); P.-E. Morange (P.); Mountford, J. (Joanne); Muckenthaler, M. (Martina); C. Müller-Tidow (Carsten); Mumford, A. (Andrew); B. Nadel (Bertrand); Navarro, J.-T. (Jose-Tomas); El Nemer, W. (Wassim); Noizat-Pirenne, F. (France); O’Mahony, B. (Brian); J. Oldenburg (Johannes); Olsson, M. (Martin); R.A. Oostendorp (Robert); A. Palumbo (Antonio); F. Passamonti (Francesco); R. Patient (Roger); De Latour, R.P. (Regis Peffault); F. Pflumio (Françoise); Pierelli, L. (Luca); Piga, A. (Antonio); Pollard, D. (Debra); M.H.G.P. Raaijmakers (Marc H.G.P.); J. Radford (John); Rambach, R. (Ralf); Koneti Rao, A.; Raslova, H. (Hana); Rebulla, P. (Paolo); Rees, D. (David); V. Ribrag (Vincent); A.W. Rijneveld (Anita); Rinalducci, S. (Sara); T. Robak (Tadeusz); Roberts, I. (Irene); Rodrigues, C. (Charlene); F.R. Rosendaal (Frits); Rosenwald, A. (Andreas); Rule, S. (Simon); R. Russo (Roberta); Saglio, G. (Guiseppe); Sanchez, M. (Mayka); Scharf, R.E. (Rüdiger E.); Schlenke, P. (Peter); Semple, J. (John); J. Sierra (Jorge); So-Osman, C. (Cynthia); Soria, J.M. (José Manuel); K. Stamatopoulos (K.); Stegmayr, B. (Bernd); H. Stunnenberg (Henk); D.W. Swinkels (Dorine); Barata, J.P.T. (João Pedro Taborda); T. Taghon (Tom); Taher, A. (Ali); E. Terpos (Evangelos); Thachil, J. (Jecko); Tissot, J.D. (Jean Daniel); I.P. Touw (Ivo); Toye, A. (Ash); Trappe, R. (Ralf); Traverse-Glehen, A. (Alexandra); Unal, S. (Sule); S. Vaulont (Sophie); V. Viprakasit (Vip); Vitolo, U. (Umberto); R. van Wijk (Richard); Wójtowicz, A. (Agnieszka); S. Zeerleder (Sacha); B. Zieger (Barbara)

    2016-01-01

    textabstractThe European Hematology Association (EHA) Roadmap for European Hematology Research highlights major achievements in diagnosis and treatment of blood disorders and identifies the greatest unmet clinical and scientific needs in those areas to enable better funded, more focused European hem

  5. Prospective registration and results disclosure of clinical trials in the Americas: a roadmap toward transparency.

    Science.gov (United States)

    Krleža-Jeriç, Karmela; Lemmens, Trudo; Reveiz, Ludovic; Cuervo, Luis Gabriel; Bero, Lisa Anne

    2011-07-01

    The objective of this article is to propose a roadmap toward transparency of clinical trials in the Americas by their prospective registration and results disclosure. This will broaden access to more complete and accurate data and facilitate evidence-informed decision-making and participation in research. Consequently, it should have a positive impact on people's health and should promote trust in health research. Existing initiatives were identified, registration of trials was analyzed following the World Health Organization (WHO) standards on trial registration, and a roadmap is proposed to address the gaps in advancing transparency. The analysis shows that, in spite of numerous regional and country initiatives, clinical trials taking place in nonEnglish-speaking parts of the Americas are underregistered. A roadmap is proposed to enhance research governance and good research practice by improving the transparency of clinical trials. The proposed roadmap includes strategies for implementing WHO international standards for trial registration, for developing international standards of public disclosure of trial results, and for a potential role of the Pan American Health Organization.

  6. U.S. Department of Energy Office of Indian Energy Policy and Programs: Strategic Roadmap 2025

    Energy Technology Data Exchange (ETDEWEB)

    2016-03-01

    The U.S. Department of Energy Office of Indian Energy Policy and Programs Strategic Roadmap 2025 outlines strategic target areas and tactical actions to ensure the Office remains aligned with its congressional mandates and DOE goals, and that it can be responsive to changing conditions in Indian Country and the nation.

  7. 75 FR 15710 - Submission for OMB Review; Comment Request; Process Evaluation of the NIH's Roadmap...

    Science.gov (United States)

    2010-03-30

    ... make decisions about structural or procedural changes within NIH that may be necessary to support cross... Evaluation of the NIH's Roadmap Interdisciplinary Research Work Group Initiatives SUMMARY: Under the... or IC), the National Institutes of Health has submitted to the Office of Management and Budget...

  8. Anti-proliferative properties of commercial Pelargonium sidoides tincture, with cell-cycle G0/G1 arrest and apoptosis in Jurkat leukaemia cells.

    Science.gov (United States)

    Pereira, Andreia; Bester, Megan; Soundy, Puffy; Apostolides, Zeno

    2016-09-01

    Context Pelargonium sidoides DC (Geraniaceae) is an important medicinal plant indigenous to South Africa and Lesotho. Previous studies have shown that root extracts are rich in polyphenolic compounds with antibacterial, antiviral and immunomodulatory activities. Little is known regarding the anticancer properties of Pelargonium sidoides extracts. Objective This study evaluates the anti-proliferative effects of a Pelargonium sidoides radix mother tincture (PST). Materials and methods The PST was characterized by LC-MS/MS. Anti-proliferative activity was evaluated in the pre-screen panel of the National Cancer Institute (NCI-H460, MCF-7 and SF-268) and the Jurkat leukaemia cell line at concentrations of 0-150 μg/mL. The effect on cell growth was determined with sulphorhodamine B and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assays after 72 h. The effect on cell cycle and apoptosis induction in Jurkat cells was determined by flow cytometry with propidium iodide and Annexin V: fluorescein isothiocyanate staining. Results Dihydroxycoumarin sulphates, gallic acid as well as gallocatechin dimers and trimers were characterized in PST by mass spectrometry. Moderate anti-proliferative effects with GI50 values between 40 and 80 μg/mL were observed in the NCI-pre-screen panel. Strong activity observed with Jurkat cells with a GI50 value of 6.2 μg/mL, significantly better than positive control 5-fluorouracil (GI50 value of 9.7 μg/mL). The PST arrested Jurkat cells at the G0/G1 phase of the cell cycle and increased the apoptotic cells from 9% to 21%, while the dead cells increased from 4% to 17%. Conclusion We present evidence that P. sidoides has cancer cell type-specific anti-proliferative effects and may be a source of novel anticancer molecules.

  9. Cytogenetic and microtubule array effects of the zineb-containing commercial fungicide formulation Azzurro(®) on meristematic root cells of Allium cepa L.

    Science.gov (United States)

    Andrioli, Nancy B; Soloneski, Sonia; Larramendy, Marcelo L; Mudry, Marta D

    2012-02-18

    Zineb [ethylene bis(dithiocarbamate) zinc] is a widely employed foliar fungicide for agricultural and industrial applications. Allium cepa L. is a reliable model for the assessment of xenobiotic genotoxicity and cytotoxicity. We evaluated the effects of the zineb-containing commercial formulation Azzurro(®) (70% zineb) in cell cycle stages of the meristem root cells of A. cepa. The mitotic index (MI), chromosomal aberrations at anaphase/telophase (CAs), micronuclei (MN), and abnormalities in immunodetected microtubule structures, e.g., preprophasic band (PPB), mitotic spindle (MS), and phragmoplast (Phrag), were used as end-points. Azzurro(®) (1 and 10μg/ml) induced a significant increase in the frequency of CAs (P<0.05), and the higher concentration inhibited the MI (P<0.05) compared to control values. The frequency of MN did not differ from control values at any concentration. Treatment with 1μg/ml Azzurro(®) induced a significant increase in the frequency of abnormal PPB (P<0.01), MS (P<0.001), and Phrag (P<0.01) and, at 10μg/ml, enhancements in the frequencies of abnormal MS (P<0.05) and Phrag (P<0.05) were seen. A tubulin immunodetection assay showed that exposure to Azzurro(®) interferes with normal assembly of microtubule structures during mitosis.

  10. Engineered yeast whole-cell biocatalyst for direct degradation of alginate from macroalgae and production of non-commercialized useful monosaccharide from alginate.

    Science.gov (United States)

    Takagi, Toshiyuki; Yokoi, Takahiro; Shibata, Toshiyuki; Morisaka, Hironobu; Kuroda, Kouichi; Ueda, Mitsuyoshi

    2016-02-01

    Alginate is a major component of brown macroalgae. In macroalgae, an endolytic alginate lyase first degrades alginate into oligosaccharides. These oligosaccharides are further broken down into monosaccharides by an exolytic alginate lyase. In this study, genes encoding various alginate lyases derived from alginate-assimilating marine bacterium Saccharophagus degradans were isolated, and their enzymes were displayed using the yeast cell surface display system. Alg7A-, Alg7D-, and Alg18J-displaying yeasts showed endolytic alginate lyase activity. On the other hand, Alg7K-displaying yeast showed exolytic alginate lyase activity. Alg7A, Alg7D, Alg7K, and Alg18J, when displayed on yeast cell surface, demonstrated both polyguluronate lyase and polymannuronate lyase activities. Additionally, polyguluronic acid could be much easily degraded by Alg7A, Alg7K, and Alg7D than polymannuronic acid. In contrast, polymannuronic acid could be much easily degraded by Alg18J than polyguluronic acid. We further constructed yeasts co-displaying endolytic and exolytic alginate lyases. Degradation efficiency by the co-displaying yeasts were significantly higher than single alginate lyase-displaying yeasts. Alg7A/Alg7K co-displaying yeast had maximum alginate degrading activity, with production of 1.98 g/L of reducing sugars in a 60-min reaction. This system developed, along with our findings, will contribute to the efficient utilization and production of useful and non-commercialized monosaccharides from alginate by Saccharomyces cerevisiae.

  11. Biological Response of Human Bone Marrow-Derived Mesenchymal Stem Cells to Commercial Tantalum Coatings with Microscale and Nanoscale Surface Topographies

    Science.gov (United States)

    Skoog, Shelby A.; Kumar, Girish; Goering, Peter L.; Williams, Brian; Stiglich, Jack; Narayan, Roger J.

    2016-06-01

    Tantalum is a promising orthopaedic implant coating material due to its robust mechanical properties, corrosion resistance, and excellent biocompatibility. Previous studies have demonstrated improved biocompatibility and tissue integration of surface-treated tantalum coatings compared to untreated tantalum. Surface modification of tantalum coatings with biologically inspired microscale and nanoscale features may be used to evoke optimal tissue responses. The goal of this study was to evaluate commercial tantalum coatings with nanoscale, sub-microscale, and microscale surface topographies for orthopaedic and dental applications using human bone marrow-derived mesenchymal stem cells (hBMSCs). Tantalum coatings with different microscale and nanoscale surface topographies were fabricated using a diffusion process or chemical vapor deposition. Biological evaluation of the tantalum coatings using hBMSCs showed that tantalum coatings promote cellular adhesion and growth. Furthermore, hBMSC adhesion to the tantalum coatings was dependent on surface feature characteristics, with enhanced cell adhesion on sub-micrometer- and micrometer-sized surface topographies compared to hybrid nano-/microstructures. Nanostructured and microstructured tantalum coatings should be further evaluated to optimize the surface coating features to promote osteogenesis and enhance osseointegration of tantalum-based orthopaedic implants.

  12. Technology Roadmaps - Electric and plug-in hybrid electric vehicles (EV/PHEV)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-06-15

    The mass deployment of electric and plug-in hybrid electric vehicles (EVs and PHEVs) that rely on low greenhouse gas (GHG) emission electricity generation has great potential to significantly reduce the consumption of petroleum and other high CO2-emitting transportation fuels. The vision of the Electric and Plug-in Hybrid (EV/PHEV) Vehicles Roadmap is to achieve by 2050 the widespread adoption and use of EVs and PHEVs, which together represent more than 50% of annual LDV (light duty vehicle) sales worldwide. In addition to establishing a vision, this roadmap sets strategic goals to achieve it, and identifies the steps that need to be taken to accomplish these goals. This roadmap also outlines the roles and collaboration opportunities for different stakeholders and shows how government policy can support the overall achievement of the vision. The strategic goals for attaining the widespread adoption and use of EVs and PHEVs worldwide by 2050 cover the development of the EV/PHEV market worldwide through 2030 and involve targets that align with global targets to stabilise GHG concentrations. These technology-specific goals include the following: Set targets for electric-drive vehicle sales; Develop coordinated strategies to support the market introduction of electric-drive vehicles; Improve industry understanding of consumer needs and behaviours; Develop performance metrics for characterising vehicles; Foster energy storage RD and D initiatives to reduce costs and address resource-related issues; and, Develop and implement recharging infrastructure. The roadmap outlines additional recommendations that must be considered in order to successfully meet the technology milestones and strategic goals. These recommendations include the following: Use a comprehensive mix of policies that provide a clear framework and balance stakeholder interests; Engage in international collaboration efforts; and, Address policy and industry needs at a national level. The IEA will work in an

  13. Experimental infection of commercial layers with wild or attenuated Salmonella Gallinarum mutant strains: anatomic pathology, total blood cell count and serum protein levels

    Directory of Open Access Journals (Sweden)

    KO Garcia

    2013-06-01

    Full Text Available The aim of the present study was to comparatively evaluate hemogram, blood serum components and anatomopathologic alterations in commercial layers experimentally challenged with an attenuated vaccine candidate strain (SG∆cobS∆cbiA and other two pathogenic strains (SGDcobS and SGNalr of Gallinarum (SG. In total, 280 commercial layers were randomly divided into 4 groups (G1, G2, G3 and G4. At five days of age, birds from groups G1 received approximately 107 colony forming units (CFU of SGDcobS; meanwhile birds from group G2 and G3 received the same dose of SGNalr and SG∆cobS∆cbiA, respectively. Birds from G4 were not infected. At 24 hours before (DBI and 24 hours after (1 DAI, and three (3 DAI, five (5 DAI, seven (7 DAI ten (10 DAI, and fifteen (15 DAI days after the infection, 10 birds of each group were humanely killed and blood samples collected to hematological and serum tests. Samples of liver, spleen, thymus, bursa of Fabricius, kidney and heart were also collected for the histological examination. Birds inoculated with SGDcobS and SGNalr showed similar alterations in hemogram, blood serum components and anatomopathologic exams. On the other hand, the exams of birds inoculated with SG∆cobS∆cbiA strain were similar to those of the uninfected birds. However, changes could be noticed in levels of uric acid and cholesterol during the course of the infection of birds from G3. Decrease in levels of light IgG 3 DAI was also observed in birds from this group. Pyknosis in kidney cells was a microscopic alteration found in birds from G3. Further studies must be done to verify if these alterations will not interfere in the performance of the vaccinate birds with SG∆cobS∆cbiA strain.

  14. Focused Logistics, Joint Vision 2010: A Joint Logistics Roadmap

    Science.gov (United States)

    2010-01-01

    such best commercial business practices as Activity Based Costing ( ABC ), Activity Based Man- agement ( ABM ), and other total quality initiatives, will...Joint Warfighting Center, Fort Monroe, Virginia C-1 APPENDIX C Acronyms ABC Activity Based Costing ABM Activity Based Management ACSA Acquisition and

  15. Advanced Combustion and Emission Control Technical Team Roadmap

    Energy Technology Data Exchange (ETDEWEB)

    None

    2013-06-01

    The Advanced Combustion and Emission Control (ACEC) Technical Team is focused on removing technical barriers to the commercialization of advanced, high-efficiency, emission-compliant internal combustion (IC) engines for light-duty vehicle powertrains (i.e., passenger car, minivan, SUV, and pickup trucks).

  16. Roadmap on optical rogue waves and extreme events

    Science.gov (United States)

    Akhmediev, Nail; Kibler, Bertrand; Baronio, Fabio; Belić, Milivoj; Zhong, Wei-Ping; Zhang, Yiqi; Chang, Wonkeun; Soto-Crespo, Jose M.; Vouzas, Peter; Grelu, Philippe; Lecaplain, Caroline; Hammani, K.; Rica, S.; Picozzi, A.; Tlidi, Mustapha; Panajotov, Krassimir; Mussot, Arnaud; Bendahmane, Abdelkrim; Szriftgiser, Pascal; Genty, Goery; Dudley, John; Kudlinski, Alexandre; Demircan, Ayhan; Morgner, Uwe; Amiraranashvili, Shalva; Bree, Carsten; Steinmeyer, Günter; Masoller, C.; Broderick, Neil G. R.; Runge, Antoine F. J.; Erkintalo, Miro; Residori, S.; Bortolozzo, U.; Arecchi, F. T.; Wabnitz, Stefan; Tiofack, C. G.; Coulibaly, S.; Taki, M.

    2016-06-01

    this point of view, a number of the scientists who work in this area of research have come together to present their research in a single review article that will greatly benefit all interested parties of this research direction. Whether the authors of this ‘roadmap’ have similar views or different from the original concept, the potential reader of the review will enrich their knowledge by encountering most of the existing views on the subject. Previously, a special issue on optical rogue waves (2013 J. Opt. 15 060201) was successful in achieving this goal but over two years have passed and more material has been published in this quickly emerging subject. Thus, it is time for a roadmap that may stimulate and encourage further research.

  17. Strategic Roadmap for the U.S. Geoscience Information Network

    Science.gov (United States)

    Allison, M. L.; Gallagher, K. T.; Richard, S. M.; Hutchison, V. B.

    2012-04-01

    An external advisory working group has prepared a 5-year strategic roadmap for the U.S. Geoscience Information Network (USGIN). USGIN is a partnership of the Association of American State Geologists (AASG) and the U.S. Geological Survey (USGS), who formally agreed in 2007 to develop a national geoscience information framework that is distributed, interoperable, uses open source standards and common protocols, respects and acknowledges data ownership, fosters communities of practice to grow, and develops new Web services and clients. The intention of the USGIN is to benefit the geological surveys by reducing the cost of online data publication and access provision, and to benefit society through easier (lower cost) access to public domain geoscience data. This information supports environmental planning, resource-development, hazard mitigation design, and decision-making. USGIN supposes that sharing resources for system development and maintenance, standardizing data discovery and creating better access mechanisms, causes cost of data access and maintenance to be reduced. Standardization in a wide variety of business domains provides economic benefits that range between 0.2 and 0.9% of the gross national product. We suggest that the economic benefits of standardization also apply in the informatics domain. Standardized access to rich data resources will create collaborative opportunities in science and business. Development and use of shared protocols and interchange formats for data publication will create a market for user applications, facilitating geoscience data discovery and utility for the benefit of society. The USGIN Working Group envisions further development of tools and capabilities, in addition to extending the community of practice that currently involves geoinformatics practitioners from the USGS and AASG. Promoting engagement and participation of the state geological surveys, and increasing communication between the states, USGS, and other

  18. 基于技术推力的外向开放式创新技术路线图研究%Study on Technology Roadmapping for Outbound Open Innovation Based on Technology Push

    Institute of Scientific and Technical Information of China (English)

    盛济川

    2012-01-01

    由于外向开放式创新可以为企业赢得巨大的战略利益和收益,企业需要在技术商业化过程中同时兼顾内部和外部的技术开发,并寻找二者间的均衡点。在传统T—plan方法的基础上,在外向开放式创新中引入技术路线图方法,提出了外向开放式创新技术推力路线图(TPROOI),并举例说明该方法在企业外向开放式创新中的应用。%Outbound open innovation offers great strategic benefits and revenues, so firms need to take into account the internal and external technology exploitation in the process of technology commercialize, and find the equilibri- um point between them. Based on traditional T-plan method, the method of technology push roadmapping for out- bound open innovation (TPROOI) is proposed though introducing technology roadmapping (TRM) into outbound open innovation, and an example is shown in this article. The method may help firms find the best way of technology commercialize in both product and technology market, and provide an effective tool for firms to implement outbound open innovation.

  19. The Human Space Life Sciences Critical Path Roadmap Project: A Strategy for Human Space Flight through Exploration-Class Missions

    Science.gov (United States)

    Sawin, Charles F.

    1999-01-01

    The product of the critical path roadmap project is an integrated strategy for mitigating the risks associated with human exploration class missions. It is an evolving process that will assure the ability to communicate the integrated critical path roadmap. Unlike previous reports, this one will not sit on a shelf - it has the full support of the JSC Space and Life Sciences Directorate (SA) and is already being used as a decision making tool (e.g., budget and investigation planning for Shuttle and Space Station mission). Utility of this product depends on many efforts, namely: providing the required information (completed risk data sheets, critical question information, technology data). It is essential to communicate the results of the critical path roadmap to the scientific community - this meeting is a good opportunity to do so. The web site envisioned for the critical path roadmap will provide the capability to communicate to a broader community and to track and update the system routinely.

  20. Commercial Buildings Characteristics, 1992

    Energy Technology Data Exchange (ETDEWEB)

    1994-04-29

    Commercial Buildings Characteristics 1992 presents statistics about the number, type, and size of commercial buildings in the United States as well as their energy-related characteristics. These data are collected in the Commercial Buildings Energy Consumption Survey (CBECS), a national survey of buildings in the commercial sector. The 1992 CBECS is the fifth in a series conducted since 1979 by the Energy Information Administration. Approximately 6,600 commercial buildings were surveyed, representing the characteristics and energy consumption of 4.8 million commercial buildings and 67.9 billion square feet of commercial floorspace nationwide. Overall, the amount of commercial floorspace in the United States increased an average of 2.4 percent annually between 1989 and 1992, while the number of commercial buildings increased an average of 2.0 percent annually.

  1. 3D Hierarchical Pt-Nitrogen-Doped-Graphene-Carbonized Commercially Available Sponge as a Superior Electrocatalyst for Low-Temperature Fuel Cells.

    Science.gov (United States)

    Zhao, Lei; Sui, Xu-Lei; Li, Jia-Long; Zhang, Jing-Jia; Zhang, Li-Mei; Wang, Zhen-Bo

    2016-06-29

    Three-dimensional hierarchical nitrogen-doped graphene (3D-NG) frameworks were successfully fabricated through a feasible solution dip-coating method with commercially available sponges as the initial backbone. A spongy template can help hinder the graphene plates restacking in the period of the annealing process. The Pt/3D-NG catalyst was synthesized employing a polyol reduction process. The resultant Pt/3D-NG exhibits 2.3 times higher activity for methanol electro-oxidation along with the improvement in stability as compared with Pt/G owing to their favorable features including large specific surface area, high pore volume, high N doping level, and the homogeneous dispersion of Pt nanoparticles. Besides, Pt/3D-NG also presents high oxygen reduction reaction (ORR) performance in acid media when compared with Pt/3D-G and Pt/G. This work raises a valid solution for the fabrication of 3D functional freestanding graphene-based composites for a variety of applications in fuel cell catalysis, energy storage, and conversion.

  2. Solid Oxide Fuel Cell APU Feasibility Study for a Long Range Commercial Aircraft Using UTC ITAPS Approach. Volume 1; Aircraft Propulsion and Subsystems Integration Evaluation

    Science.gov (United States)

    Srinivasan, Hari; Yamanis, Jean; Welch, Rick; Tulyani, Sonia; Hardin, Larry

    2006-01-01

    The objective of this contract effort was to define the functionality and evaluate the propulsion and power system benefits derived from a Solid Oxide Fuel Cell (SOFC) based Auxiliary Power Unit (APU) for a future long range commercial aircraft, and to define the technology gaps to enable such a system. The study employed technologies commensurate with Entry into Service (EIS) in 2015. United Technologies Corporation (UTC) Integrated Total Aircraft Power System (ITAPS) methodologies were used to evaluate system concepts to a conceptual level of fidelity. The technology benefits were captured as reductions of the mission fuel burn and emissions. The baseline aircraft considered was the Boeing 777-200ER airframe with more electric subsystems, Ultra Efficient Engine Technology (UEET) engines, and an advanced APU with ceramics for increased efficiency. In addition to the baseline architecture, four architectures using an SOFC system to replace the conventional APU were investigated. The mission fuel burn savings for Architecture-A, which has minimal system integration, is 0.16 percent. Architecture-B and Architecture-C employ greater system integration and obtain fuel burn benefits of 0.44 and 0.70 percent, respectively. Architecture-D represents the highest level of integration and obtains a benefit of 0.77 percent.

  3. Roadmap VNMI (Association of the Dutch Metallurgical Industry). Input of renewable energy; Roadmap VNMI. Inzet van hernieuwbare energie

    Energy Technology Data Exchange (ETDEWEB)

    Plomp, A.J.; Luxembourg, S.L.; Seebregts, A.J.; Lensink, S.M. [ECN Beleidsstudies, Petten (Netherlands)

    2011-04-15

    , a pre-defined calculation for this new subsidy concept has been reviewed. A long-term, fixed power sales price for the participating companies of 50 euro/MWh and a calculated Carbon Leakage compensation, based on a CO2 emission factor of 581 kg/MWh, resulted in a cost decrease for the Dutch government for the majority of the calculated price scenarios. For those scenario variants in which these conditions resulted in a cost increase for the Dutch government, the long-term fixed power sales price was increased to mitigate the additional costs. From this analysis it follows that a fixed power sales price of 62 euro/MWh is sufficient to prevent additional costs for the highest price scenario. [Dutch] De Nederlandse metaalindustrie en metaalgieterijen participeren in convenanten om hun pro-ductie energie-efficienter uit te voeren. In samenspraak met AgentschapNL heeft deze sector besloten om een 'Roadmap 2030' te ontwikkelen, waarin verschillende strategieen worden ge-schetst om energie-efficientie te bereiken. Onderdeel hiervan is de mogelijke toepassing van hernieuwbare elektriciteit, opgewekt via derden of direct voor eigen gebruik. De metaalsector heeft daarom ECN gevraagd wat de verwachte kosten en baten zijn van een omschakeling naar de hernieuwbare elektriciteitsopties: zon (PV), wind en biomassa op de korte en lange termijn en wat volgt uit een vergelijking van de kosten met de baten. In aanvulling hierop is een nieuw door de sector voorgesteld subsidievoorstel (het 'DAAN' concept) voor hernieuwbare elektriciteit geanalyseerd. Uit dit onderzoek blijkt dat tot 2020, behoudens gunstige omstandigheden voor wind op land en biomassameestook, hernieuwbare elektriciteit op of boven de gemiddelde elektriciteitsprijs wordt geproduceerd en dat de kosten hoger zijn dan de baten. Hoewel de onzekerheid toeneemt, laat de doorkijk voor de periode 2020-2030 zien dat de productiekosten van wind op land dan onder de verwachte gemiddelde elektriciteitsprijs

  4. Accuracy of the Fluorescence-Activated Cell Sorting Assay for the Aquaporin-4 Antibody (AQP4-Ab): Comparison with the Commercial AQP4-Ab Assay Kit

    Science.gov (United States)

    Kim, Yoo-Jin; Cheon, So Young; Kim, Boram; Jung, Kyeong Cheon; Park, Kyung Seok

    2016-01-01

    Background The aquaporin-4 antibody (AQP4-Ab) is a disease-specific autoantibody to neuromyelitis optica (NMO). We aimed to evaluate the accuracy of the FACS assay in detecting the AQP4-Ab compared with the commercial cell-based assay (C-CBA) kit. Methods Human embryonic kidney-293 cells were transfected with human aquaporin-4 (M23) cDNA. The optimal cut off values of FACS assay was tested using 1123 serum samples from patients with clinically definite NMO, those at high risk for NMO, patients with multiple sclerosis, patients with other idiopathic inflammatory demyelinating diseases, and negative controls. The accuracy of FACS assay and C-CBA were compared in consecutive 225 samples that were collected between January 2014 and June 2014. Results With a cut-off value of MFIi of 3.5 and MFIr of 2.0, the receiver operating characteristic curve for the FACS assay showed an area under the curve of 0.876. Among 225 consecutive sera, the FACS assay and C-CBA had a sensitivity of 77.3% and 69.7%, respectively, in differentiating the sera of definite NMO patients from sera of controls without IDD or of MS. Both assay had a good specificity of 100% in it. The overall positivity of the C-CBA among FACS-positive sera was 81.5%; moreover, its positivity was low as 50% among FACS-positive sera with relatively low MFIis. Conclusions Both the FACS assay and C-CBA are sensitive and highly specific assays in detecting AQP4-Ab. However, in some sera with relatively low antibody titer, FACS-assay can be a more sensitive assay option. In real practice, complementary use of FACS assay and C-CBA will benefit the diagnosis of NMO patients, because the former can be more sensitive among low titer sera and the latter are easier to use therefore can be widely used. PMID:27658059

  5. Comparison Between Research-Grade and Commercially Available SnO2 for Thin-Film CdTe Solar Cells: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Li, X.; Pankow, J.; To, B.; Gessert, T.

    2008-05-01

    Compared to commercial SnO2 (with similar film thickness and sheet resistance), research-grade SnO2 has higher optical transmittance and higher electron mobility. Based on our study, changing the glass substrate and improving the SnO2 quality could improve the optical properties of commercial SnO2.

  6. A roadmap for bridging basic and applied research in forensic entomology.

    Science.gov (United States)

    Tomberlin, J K; Mohr, R; Benbow, M E; Tarone, A M; VanLaerhoven, S

    2011-01-01

    The National Research Council issued a report in 2009 that heavily criticized the forensic sciences. The report made several recommendations that if addressed would allow the forensic sciences to develop a stronger scientific foundation. We suggest a roadmap for decomposition ecology and forensic entomology hinging on a framework built on basic research concepts in ecology, evolution, and genetics. Unifying both basic and applied research fields under a common umbrella of terminology and structure would facilitate communication in the field and the production of scientific results. It would also help to identify novel research areas leading to a better understanding of principal underpinnings governing ecosystem structure, function, and evolution while increasing the accuracy of and ability to interpret entomological evidence collected from crime scenes. By following the proposed roadmap, a bridge can be built between basic and applied decomposition ecology research, culminating in science that could withstand the rigors of emerging legal and cultural expectations.

  7. The Technology Roadmap for Plant/Crop-Based Renewable Resources 2020

    Energy Technology Data Exchange (ETDEWEB)

    None

    1999-02-01

    The long-term well-being of the nation and maintenance of a sustainable leadership position in agriculture, forestry, and manufacturing, clearly depend on current and near-term support of multidisciplinary research for the development of a reliable renewable resource base. This document sets a roadmap and priorities for that research. America needs leadership that will continue to recognize, support, and move rapidly to meet the need to expand the use of sustainable renewable resources. This roadmap has highlighted potential ways for progress and has identified goals in specific components of the system. Achieving success with these goals will provide the opportunity to hit the vision target of a fivefold increase in renewable resource use by 2020.

  8. Mixed-Variable Requirements Roadmaps and their Role in the Requirements Engineering of Adaptive Systems

    CERN Document Server

    Jureta, Ivan; Ernst, Neil A

    2011-01-01

    The requirements roadmap concept is introduced as a solution to the problem of the requirements engineering of adaptive systems. The concept requires a new general definition of the requirements problem which allows for quantitative (numeric) variables, together with qualitative (binary boolean) propositional variables, and distinguishes monitored from controlled variables for use in control loops. We study the consequences of these changes, and argue that the requirements roadmap concept bridges the gap between current general definitions of the requirements problem and its notion of solution, and the research into the relaxation of requirements, the evaluation of their partial satisfaction, and the monitoring and control of requirements, all topics of particular interest in the engineering of requirements for adaptive systems [Cheng et al. 2009]. From the theoretical perspective, we show clearly and formally the fundamental differences between more traditional conception of requirements engineering (e.g., Z...

  9. A technology roadmap of assistive technologies for dementia care in Japan.

    Science.gov (United States)

    Sugihara, Taro; Fujinami, Tsutomu; Phaal, Robert; Ikawa, Yasuo

    2015-01-01

    The number of elderly people in Japan is growing, which raises the issue of dementia, as the probability of becoming cognitively impaired increases with age. There is an increasing need for caregivers, who are well-trained, experienced and can pay special attention to the needs of people with dementia. Technology can play an important role in helping such people and their caregivers. A lack of mutual understanding between caregivers and researchers regarding the appropriate uses of assistive technologies is another problem. A vision of person-centred care based on the use of information and communication technology to maintain residents' autonomy and continuity in their lives is presented. Based on this vision, a roadmap and a list of challenges to realizing assistive technologies have been developed. The roadmap facilitates mutual understanding between caregivers and researchers, resulting in appropriate technologies to enhance the quality of life of people with dementia.

  10. A METHODOLOGY FOR DEVELOPING A ROADMAP TOWARDS LOCAL LOW-CARBON SOCIETY COSIDERING IMPLEMENTATION COST

    Science.gov (United States)

    Gomi, Kei; Kim, Jaegyu; Matsuoka, Yuzuru

    We have developed a methodology for developing roadmaps towards low-carbon society in local government. A quantification tool called "Backcasting Tool" (BCT) was developed. BCT estimates implementation schedule of all policies and actions considering their relationship, financial constraints of the actors, and co-benefit of the policies. The methodology was applied in Shiga prefecture, Japan, and a roadmap which consists of more than 240 policies is estimated considering direct costs paid by public and private sectors. As a result, cumulative implementation cost was 7.3 trillion yen in which public sector bear 17%. Cumulative emission reduction was 101MtCO2, and average emission reduction cost was 73 thousand yen/tCO2.

  11. Roadmap to PLE - A Research Route to Empower the Use of Personal Learning Environments (PLEs

    Directory of Open Access Journals (Sweden)

    Maria Chiara Pettenati

    2010-10-01

    Full Text Available In this position paper we argue that in order to design, deploy and evaluate institutional Personal Learning Environments, a system-level Roadmap should be developed accounting for the progressive expansion towards the following evolutions directions: from closed (VLE to Open Learning Environments (OLE; from the individual-group, to individual-network and individual-collective relations; from using structured learning resources to using any type of content; from being instructor/institution-led by being self-regulated and self-managed; from being aimed at learning in the university system to supporting work-based learning; from being centered around web 2.0 to being empowered by web 3.0 tools and technologies. In order to accompany the development of such a Roadmap, an operational definition and hexagonal model of the PLE is presented in this paper together with its three-steps evolutionary process.

  12. Roadmapping and Strategy in Science, Technology and Innovation: Why connectivity matters

    DEFF Research Database (Denmark)

    Ricard, Lykke Margot

    The thesis focuses on the coordination of technology-intensive innovation activities at both sector and firm levels, supported by the use of the strategic roadmapping method. Investigations combine qualitative and quantitative research methods; using a narrative approach in the form of interviews...... to uncover innovation and technology barriers, and a social network analysis of stakeholders’ role in relation to two technology platforms: TPWind and ZEP (Zero Emission Platform), during a five-year period when the roadmaps 2020 were developed. In this respect, the thesis emphasizes the view of innovation...... as an interactive process to develop competences among technology users, producers, research institutions, and politicians. As a result, knowledge on how the platforms evolved, and their dynamics, provide new reflections on the innovation systems approach: that connectivity seems to change along the changes...

  13. On commercial media bias

    OpenAIRE

    Germano, Fabrizio

    2008-01-01

    Within the spokes model of Chen and Riordan (2007) that allows for non-localized competition among arbitrary numbers of media outlets, we quantify the effect of concentration of ownership on quality and bias of media content. A main result shows that too few commercial outlets, or better, too few separate owners of commercial outlets can lead to substantial bias in equilibrium. Increasing the number of outlets (commercial and non-commercial) tends to bring down this bias; but the strongest ef...

  14. Toward Simulating Realistic Pursuit-Evasion Using a Roadmap-Based Approach

    KAUST Repository

    Rodriguez, Samuel

    2010-01-01

    In this work, we describe an approach for modeling and simulating group behaviors for pursuit-evasion that uses a graph-based representation of the environment and integrates multi-agent simulation with roadmap-based path planning. We demonstrate the utility of this approach for a variety of scenarios including pursuit-evasion on terrains, in multi-level buildings, and in crowds. © 2010 Springer-Verlag Berlin Heidelberg.

  15. Technology Assessment and Roadmap for the Emergency Radiation Dose Assessment Program

    Energy Technology Data Exchange (ETDEWEB)

    Turteltaub, K W; Hartman-Siantar, C; Easterly, C; Blakely, W

    2005-10-03

    A Joint Interagency Working Group (JIWG) under the auspices of the Department of Homeland Security Office of Research and Development conducted a technology assessment of emergency radiological dose assessment capabilities as part of the overall need for rapid emergency medical response in the event of a radiological terrorist event in the United States. The goal of the evaluation is to identify gaps and recommend general research and development needs to better prepare the Country for mitigating the effects of such an event. Given the capabilities and roles for responding to a radiological event extend across many agencies, a consensus of gaps and suggested development plans was a major goal of this evaluation and road-mapping effort. The working group consisted of experts representing the Departments of Homeland Security, Health and Human Services (Centers for Disease Control and the National Institutes of Health), Food and Drug Administration, Department of Defense and the Department of Energy's National Laboratories (see appendix A for participants). The specific goals of this Technology Assessment and Roadmap were to: (1) Describe the general context for deployment of emergency radiation dose assessment tools following terrorist use of a radiological or nuclear device; (2) Assess current and emerging dose assessment technologies; and (3) Put forward a consensus high-level technology roadmap for interagency research and development in this area. This report provides a summary of the consensus of needs, gaps and recommendations for a research program in the area of radiation dosimetry for early response, followed by a summary of the technologies available and on the near-term horizon. We then present a roadmap for a research program to bring present and emerging near-term technologies to bear on the gaps in radiation dose assessment and triage. Finally we present detailed supporting discussion on the nature of the threats we considered, the status of

  16. Commercial Radio as Communication.

    Science.gov (United States)

    Rothenbuhler, Eric W.

    1996-01-01

    Compares the day-to-day work routines of commercial radio with the principles of a theoretical communication model. Illuminates peculiarities of the conduct of communication by commercial radio. Discusses the application of theoretical models to the evaluation of practicing institutions. Offers assessments of commercial radio deriving from…

  17. Standing on the Shoulders of Giants: Results From the Radiation Oncology Academic Development and Mentorship Assessment Project (ROADMAP)

    Energy Technology Data Exchange (ETDEWEB)

    Holliday, Emma B. [The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Jagsi, Reshma [The University of Michigan, Ann Arbor, Michigan (United States); Thomas, Charles R. [Oregon Health Science Center Knight Cancer Institute, Portland, Oregon (United States); Wilson, Lynn D. [Department of Therapeutic Radiology, Yale University School of Medicine, Yale Cancer Center, New Haven, Connecticut (United States); Fuller, Clifton D., E-mail: cdfuller@mdanderson.org [The University of Texas MD Anderson Cancer Center, Houston, Texas (United States); Oregon Health Science Center Knight Cancer Institute, Portland, Oregon (United States)

    2014-01-01

    Purpose: To analyze survey information regarding mentorship practices and cross-correlate the results with objective metrics of academic productivity among academic radiation oncologists at US Accreditation Council for Graduate Medical Education (ACGME)-accredited residency training programs. Methods and Materials: An institutional review board-approved survey for the Radiation Oncology Academic Development and Mentorship Assessment Project (ROADMAP) was sent to 1031 radiation oncologists employed at an ACGME-accredited residency training program and administered using an international secure web application designed exclusively to support data capture for research studies. Data collected included demographics, presence of mentorship, and the nature of specific mentoring activities. Productivity metrics, including number of publications, number of citations, h-index, and date of first publication, were collected for each survey respondent from a commercially available online database, and m-index was calculated. Results: A total of 158 academic radiation oncologists completed the survey, 96 of whom reported having an academic/scientific mentor. Faculty with a mentor had higher numbers of publications, citations, and h- and m-indices. Differences in gender and race/ethnicity were not associated with significant differences in mentorship rates, but those with a mentor were more likely to have a PhD degree and were more likely to have more time protected for research. Bivariate fit regression modeling showed a positive correlation between a mentor's h-index and their mentee's h-index (R{sup 2} = 0.16; P<.001). Linear regression also showed significant correlates of higher h-index, in addition to having a mentor (P=.001), included a longer career duration (P<.001) and fewer patients in treatment (P=.02). Conclusions: Mentorship is widely believed to be important to career development and academic productivity. These results emphasize the importance of

  18. Microbial Populations in Naked Neck Chicken Ceca Raised on Pasture Flock Fed with Commercial Yeast Cell Wall Prebiotics via an Illumina MiSeq Platform.

    Directory of Open Access Journals (Sweden)

    Si Hong Park

    Full Text Available Prebiotics are non-digestible carbohydrate dietary supplements that selectively stimulate the growth of one or more beneficial bacteria in the gastrointestinal tract of the host. These bacteria can inhibit colonization of pathogenic bacteria by producing antimicrobial substances such as short chain fatty acids (SCFAs and competing for niches with pathogens within the gut. Pasture flock chickens are generally raised outdoors with fresh grass, sunlight and air, which represents different environmental growth conditions compared to conventionally raised chickens. The purpose of this study was to evaluate the difference in microbial populations from naked neck chicken ceca fed with commercial prebiotics derived from brewer's yeast cell wall via an Illumina MiSeq platform. A total of 147 day-of-hatch naked neck chickens were distributed into 3 groups consisted of 1 C: control (no prebiotic, 2 T1: Biolex® MB40 with 0.2%, and 3 T2: Leiber® ExCel with 0.2%, consistently supplemented prebiotics during the experimental period. At 8 weeks, a total of 15 birds from each group were randomly selected and ceca removed for DNA extraction. The Illumina Miseq platform based on V4 region of 16S rRNA gene was applied for microbiome analysis. Both treatments exhibited limited impact on the microbial populations at the phylum level, with no significant differences in the OTU number of Bacteroidetes among groups and an increase of Proteobacteria OTUs for the T1 (Biolex® MB40 group. In addition there was a significant increase of genus Faecalibacterium OTU, phylum Firmicutes. According to the development of next generation sequencing (NGS, microbiome analysis based on 16S rRNA gene proved to be informative on the prebiotic impact on poultry gut microbiota in pasture-raised naked neck birds.

  19. Recycling Sounds in Commercials

    DEFF Research Database (Denmark)

    Larsen, Charlotte Rørdam

    2012-01-01

    such references to the past and ‘the good old days’ can be achieved through sounds. In particular, I will look at commercials for Danish non-dairy spreads, especially for OMA margarine. These commercials are notable in that they contain a melody and a slogan – ‘Say the name: OMA margarine’ – that have basically......: in general, the soundtracks of margarine commercials seem to merge into one, they are somewhat alike. The OMA commercials are no exception, but the OMA melody makes a distinction. In general the soundtracks of OMA margarine commercials (and the use of melody) seem to have shifted from using a predominantly...

  20. A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing - t4 report*.

    Science.gov (United States)

    Basketter, David A; Clewell, Harvey; Kimber, Ian; Rossi, Annamaria; Blaauboer, Bas; Burrier, Robert; Daneshian, Mardas; Eskes, Chantra; Goldberg, Alan; Hasiwa, Nina; Hoffmann, Sebastian; Jaworska, Joanna; Knudsen, Thomas B; Landsiedel, Robert; Leist, Marcel; Locke, Paul; Maxwell, Gavin; McKim, James; McVey, Emily A; Ouédraogo, Gladys; Patlewicz, Grace; Pelkonen, Olavi; Roggen, Erwin; Rovida, Costanza; Ruhdel, Irmela; Schwarz, Michael; Schepky, Andreas; Schoeters, Greet; Skinner, Nigel; Trentz, Kerstin; Turner, Marian; Vanparys, Philippe; Yager, James; Zurlo, Joanne; Hartung, Thomas

    2012-01-01

    Systemic toxicity testing forms the cornerstone for the safety evaluation of substances. Pressures to move from traditional animal models to novel technologies arise from various concerns, including: the need to evaluate large numbers of previously untested chemicals and new products (such as nanoparticles or cell therapies), the limited predictivity of traditional tests for human health effects, duration and costs of current approaches, and animal welfare considerations. The latter holds especially true in the context of the scheduled 2013 marketing ban on cosmetic ingredients tested for systemic toxicity. Based on a major analysis of the status of alternative methods (Adler et al., 2011) and its independent review (Hartung et al., 2011), the present report proposes a roadmap for how to overcome the acknowledged scientific gaps for the full replacement of systemic toxicity testing using animals. Five whitepapers were commissioned addressing toxicokinetics, skin sensitization, repeated-dose toxicity, carcinogenicity, and reproductive toxicity testing. An expert workshop of 35 participants from Europe and the US discussed and refined these whitepapers, which were subsequently compiled to form the present report. By prioritizing the many options to move the field forward, the expert group hopes to advance regulatory science.

  1. Effective methodology to derive strategic decisions from ESA exploration technology roadmaps

    Science.gov (United States)

    Cresto Aleina, Sara; Viola, Nicole; Fusaro, Roberta; Saccoccia, Giorgio

    2016-09-01

    Top priorities in future international space exploration missions regard the achievement of the necessary maturation of enabling technologies, thereby allowing Europe to play a role commensurate with its industrial, operational and scientific capabilities. As part of the actions derived from this commitment, ESA Technology Roadmaps for Exploration represent a powerful tool to prioritise R&D activities in technologies for space exploration and support the preparation of a consistent procurement plan for space exploration technologies in Europe. The roadmaps illustrate not only the technology procurement (to TRL-8) paths for specific missions envisaged in the present timeframe, but also the achievement for Europe of technological milestones enabling operational capabilities and building blocks, essential for current and future Exploration missions. Coordination of requirements and funding sources among all European stakeholders (ESA, EU, National, and Industry) is one of the objectives of these roadmaps, that show also possible application of the technologies beyond space exploration, both at ESA and outside. The present paper describes the activity that supports the work on-going at ESA on the elaboration and update of these roadmaps and related tools, in order to criticise the followed approach and to suggest methodologies of assessment of the Roadmaps, and to derive strategic decision for the advancement of Space Exploration in Europe. After a review of Technology Areas, Missions/Programmes and related building blocks (architectures) and operational capabilities, technology applicability analyses are presented. The aim is to identify if a specific technology is required, applicable or potentially a demonstrator in the building blocks of the proposed mission concepts. In this way, for each technology it is possible to outline one or more specific plans to increase TRL up to the required level. In practice, this translates into two possible solutions: on the one

  2. European roadmap on superconductive electronics - status and perspectives

    Science.gov (United States)

    Anders, S.; Blamire, M. G.; Buchholz, F.-Im.; Crété, D.-G.; Cristiano, R.; Febvre, P.; Fritzsch, L.; Herr, A.; Il'ichev, E.; Kohlmann, J.; Kunert, J.; Meyer, H.-G.; Niemeyer, J.; Ortlepp, T.; Rogalla, H.; Schurig, T.; Siegel, M.; Stolz, R.; Tarte, E.; ter Brake, H. J. M.; Toepfer, H.; Villegier, J.-C.; Zagoskin, A. M.; Zorin, A. B.

    2010-12-01

    Executive SummaryFor four decades semiconductor electronics has followed Moore’s law: with each generation of integration the circuit features became smaller, more complex and faster. This development is now reaching a wall so that smaller is no longer any faster. The clock rate has saturated at about 3-5 GHz and the parallel processor approach will soon reach its limit. The prime reason for the limitation the semiconductor electronics experiences is not the switching speed of the individual transistor, but its power dissipation and thus heat. Digital superconductive electronics is a circuit- and device-technology that is inherently faster at much less power dissipation than semiconductor electronics. It makes use of superconductors and Josephson junctions as circuit elements, which can provide extremely fast digital devices in a frequency range - dependent on the material - of hundreds of GHz: for example a flip-flop has been demonstrated that operated at 750 GHz. This digital technique is scalable and follows similar design rules as semiconductor devices. Its very low power dissipation of only 0.1 μW per gate at 100 GHz opens the possibility of three-dimensional integration. Circuits like microprocessors and analogue-to-digital converters for commercial and military applications have been demonstrated. In contrast to semiconductor circuits, the operation of superconducting circuits is based on naturally standardized digital pulses the area of which is exactly the flux quantum Φ0. The flux quantum is also the natural quantization unit for digital-to-analogue and analogue-to-digital converters. The latter application is so precise, that it is being used as voltage standard and that the physical unit ‘Volt’ is defined by means of this standard. Apart from its outstanding features for digital electronics, superconductive electronics provides also the most sensitive sensor for magnetic fields: the Superconducting Quantum Interference Device (SQUID). Amongst

  3. European roadmap on superconductive electronics - status and perspectives

    Energy Technology Data Exchange (ETDEWEB)

    Anders, S. [Institute of Photonic Technology (IPHT), Department of Quantum Detection, Albert-Einstein-Str. 9, 07745 Jena (Germany); Blamire, M.G. [University of Cambridge, Department of Materials Science, Pembroke St, Cambridge CB2 3QZ (United Kingdom); Buchholz, F.-Im. [Physikalisch-Technische Bundesanstalt (PTB), Bundesallee 100, 38116 Braunschweig (Germany); Crete, D.-G. [Unite Mixte de Physique CNRS/THALES, 1 Avenue Augustin Fresnel, 91767 Palaiseau CEDEx (France); Cristiano, R. [Istituto di Cibernetica CNR, Via Campi Flegrei 34, 80078 Napoli (Italy); Febvre, P. [University of Savoie, IMEP-LAHC, CNRS UMR 5130, Campus scientifique, 73376 Le Bourget du Lac Cedex (France); Fritzsch, L. [Institute of Photonic Technology (IPHT), Department of Quantum Detection, Albert-Einstein-Str. 9, 07745 Jena (Germany); Herr, A. [Chalmers University of Technology, Department of Microtechnology and Nanoscience - MC2, SE-412 96 Goeteborg (Sweden); Il' ichev, E. [Institute of Photonic Technology (IPHT), Department of Quantum Detection, Albert-Einstein-Str. 9, 07745 Jena (Germany); Kohlmann, J. [Physikalisch-Technische Bundesanstalt (PTB), Bundesallee 100, 38116 Braunschweig (Germany); Kunert, J., E-mail: juergen.kunert@ipht-jena.d [Institute of Photonic Technology (IPHT), Department of Quantum Detection, Albert-Einstein-Str. 9, 07745 Jena (Germany); Meyer, H.-G. [Institute of Photonic Technology (IPHT), Department of Quantum Detection, Albert-Einstein-Str. 9, 07745 Jena (Germany); Niemeyer, J. [Physikalisch-Technische Bundesanstalt (PTB), Bundesallee 100, 38116 Braunschweig (Germany); Ortlepp, T. [Technische Universitaet Ilmenau, Theoretische Elektrotechnik, PF 10 05 65 D-98684 Ilmenau (Germany); Rogalla, H. [University of Twente, Fac. Science and Technology, P.O. Box 217, 7500 AE Enschede (Netherlands); Schurig, T. [Physikalisch-Technische Bundesanstalt (PTB), Berlin, Abbestr. 2-12, 10587 Berlin (Germany)

    2010-12-15

    Executive Summary: For four decades semiconductor electronics has followed Moore's law: with each generation of integration the circuit features became smaller, more complex and faster. This development is now reaching a wall so that smaller is no longer any faster. The clock rate has saturated at about 3-5 GHz and the parallel processor approach will soon reach its limit. The prime reason for the limitation the semiconductor electronics experiences is not the switching speed of the individual transistor, but its power dissipation and thus heat. Digital superconductive electronics is a circuit- and device-technology that is inherently faster at much less power dissipation than semiconductor electronics. It makes use of superconductors and Josephson junctions as circuit elements, which can provide extremely fast digital devices in a frequency range - dependent on the material - of hundreds of GHz: for example a flip-flop has been demonstrated that operated at 750 GHz. This digital technique is scalable and follows similar design rules as semiconductor devices. Its very low power dissipation of only 0.1 {mu}W per gate at 100 GHz opens the possibility of three-dimensional integration. Circuits like microprocessors and analogue-to-digital converters for commercial and military applications have been demonstrated. In contrast to semiconductor circuits, the operation of superconducting circuits is based on naturally standardized digital pulses the area of which is exactly the flux quantum {Phi}{sub 0}. The flux quantum is also the natural quantization unit for digital-to-analogue and analogue-to-digital converters. The latter application is so precise, that it is being used as voltage standard and that the physical unit 'Volt' is defined by means of this standard. Apart from its outstanding features for digital electronics, superconductive electronics provides also the most sensitive sensor for magnetic fields: the Superconducting Quantum Interference

  4. Germ layer induction in ESC--following the vertebrate roadmap.

    Science.gov (United States)

    Smith, Jim; Wardle, Fiona; Loose, Matt; Stanley, Ed; Patient, Roger

    2007-06-01

    Controlled differentiation of pluripotential cells takes place routinely and with great success in developing vertebrate embryos. It therefore makes sense to take note of how this is achieved and use this knowledge to control the differentiation of embryonic stem cells (ESCs). An added advantage is that the differentiated cells resulting from this process in embryos have proven functionality and longevity. This unit reviews what is known about the embryonic signals that drive differentiation in one of the most informative of the vertebrate animal models of development, the amphibian Xenopus laevis. It summarizes their identities and the extent to which their activities are dose-dependent. The unit details what is known about the transcription factor responses to these signals, describing the networks of interactions that they generate. It then discusses the target genes of these transcription factors, the effectors of the differentiated state. Finally, how these same developmental programs operate during germ layer formation in the context of ESC differentiation is summarized.

  5. A Research Roadmap for Computation-Based Human Reliability Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Boring, Ronald [Idaho National Lab. (INL), Idaho Falls, ID (United States); Mandelli, Diego [Idaho National Lab. (INL), Idaho Falls, ID (United States); Joe, Jeffrey [Idaho National Lab. (INL), Idaho Falls, ID (United States); Smith, Curtis [Idaho National Lab. (INL), Idaho Falls, ID (United States); Groth, Katrina [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-08-01

    The United States (U.S.) Department of Energy (DOE) is sponsoring research through the Light Water Reactor Sustainability (LWRS) program to extend the life of the currently operating fleet of commercial nuclear power plants. The Risk Informed Safety Margin Characterization (RISMC) research pathway within LWRS looks at ways to maintain and improve the safety margins of these plants. The RISMC pathway includes significant developments in the area of thermalhydraulics code modeling and the development of tools to facilitate dynamic probabilistic risk assessment (PRA). PRA is primarily concerned with the risk of hardware systems at the plant; yet, hardware reliability is often secondary in overall risk significance to human errors that can trigger or compound undesirable events at the plant. This report highlights ongoing efforts to develop a computation-based approach to human reliability analysis (HRA). This computation-based approach differs from existing static and dynamic HRA approaches in that it: (i) interfaces with a dynamic computation engine that includes a full scope plant model, and (ii) interfaces with a PRA software toolset. The computation-based HRA approach presented in this report is called the Human Unimodels for Nuclear Technology to Enhance Reliability (HUNTER) and incorporates in a hybrid fashion elements of existing HRA methods to interface with new computational tools developed under the RISMC pathway. The goal of this research effort is to model human performance more accurately than existing approaches, thereby minimizing modeling uncertainty found in current plant risk models.

  6. Technical Comparative Analysis of "Best of Breed" Turnkey Si-Based Processes and Equipment, to be Used to Produce a Combined Multi-entity Research and Development Technology Roadmap for Thick and Thin Silicon PV

    Energy Technology Data Exchange (ETDEWEB)

    Hovel, Harold [The Solar Energy Consortium, Kingston, NY (United States); Prettyman, Kevin [The Solar Energy Consortium, Kingston, NY (United States)

    2015-03-27

    A side-by-side analysis was done on then currently available technology, along with roadmaps to push each particular option forward. Variations in turnkey line processes can and do result in finished solar device performance. Together with variations in starting material quality, the result is a distribution of effciencies. Forensic analysis and characterization of each crystalline Si based technology will determine the most promising approach with respect to cost, efficiency and reliability. Forensic analysis will also shed light on the causes of binning variations. Si solar cells were forensically analyzed from each turn key supplier using a host of techniques

  7. Comparison Between Research-Grade SnO2 and Commercial Available SnO2 for Thin-Film CdTe Solar Cell (Poster)

    Energy Technology Data Exchange (ETDEWEB)

    Li, X.; Pankow, J.; To, B.; Gessert, T.

    2008-05-01

    A comparison between research-grade, tin-oxide (SnO{sub 2}) thin films and those available from commercial sources is performed. The research-grade SnO{sub 2} film is fabricated at NREL by low-pressure metal-organic chemical vapor deposition. The commercial SnO{sub 2} films are Pilkington Tec 8 and Tec 15 fabricated by atmospheric-pressure chemical vapor deposition. Optical, structural, and compositional analyses are performed. From the optical analysis, an estimation of the current losses due to the SnO{sub 2} layer and glass is provided. Our analysis indicates that the optical properties of commercial SnO{sub 2} could be improved for PV usage.

  8. The WHF Roadmap for Reducing CV Morbidity and Mortality Through Prevention and Control of Rheumatic Heart Disease.

    Science.gov (United States)

    Palafox, Benjamin; Mocumbi, Ana Olga; Kumar, R Krishna; Ali, Sulafa K M; Kennedy, Elizabeth; Haileamlak, Abraham; Watkins, David; Petricca, Kadia; Wyber, Rosemary; Timeon, Patrick; Mwangi, Jeremiah

    2017-03-20

    Rheumatic heart disease (RHD) is a preventable non-communicable condition that disproportionately affects the world's poorest and most vulnerable. The World Heart Federation Roadmap for improved RHD control is a resource designed to help a variety of stakeholders raise the profile of RHD nationally and globally, and provide a framework to guide and support the strengthening of national, regional and global RHD control efforts. The Roadmap identifies the barriers that limit access to and uptake of proven interventions for the prevention and control of RHD. It also highlights a variety of established and promising solutions that may be used to overcome these barriers. As a general guide, the Roadmap is meant to serve as the foundation for the development of tailored plans of action to improve RHD control in specific contexts.

  9. Recycling sound in Commercials

    Directory of Open Access Journals (Sweden)

    Charlotte Rørdam Larsen

    2012-04-01

    Full Text Available Commercials offer the opportunity for intergenerational memory and impinge on cultural memory. TV commercials for foodstuffs often make reference to past times as a way of authenticating products. This is frequently achieved using visual cues, but in this paper I would like to demonstrate how such references to the past and ‘the good old days’ can be achieved through sounds. In particular, I will look at commercials for Danish non-dairy spreads, especially for OMA margarine. These commercials are notable in that they contain a melody and a slogan – ‘Say the name: OMA margarine’ – that have basically remained the same for 70 years. Together these identifiers make OMA an interesting Danish case to study. With reference to Ann Rigney’s memorial practices or mechanisms, the study aims to demonstrate how the auditory aspects of Danish margarine commercials for frying tend to be limited in variety: in general, the soundtracks of margarine commercials seem to merge into one, they are somewhat alike. The OMA commercials are no exception, but the OMA melody makes a distinction. In general the soundtracks of OMA margarine commercials (and the use of melody seem to have shifted from using a predominantly semantic causal soundtrack to tracks using aesthetic and musicalised elements which are supposed to arouse more sensuous feelings in the consumers.

  10. Technology Roadmap: Low-Carbon Technology for the Indian Cement Industry

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-06-01

    The Indian cement industry is one of the most efficient in the world. Its efforts to reduce its carbon footprint by adopting the best available technologies and environmental practices are reflected in the achievement of reducing total CO2 emissions to an industrial average of 0.719 tCO2/t cement in 2010 from a substantially higher level of 1.12 tCO2/t cement in 1996. However, because the manufacturing process relies on the burning of limestone, it still produced 137 MtCO2 in 2010 – approximately 7% of India’s total man-made CO2 emissions. Yet opportunity for improvement exists, particularly in relation to five key levers that can contribute to emissions reductions: alternative fuel and raw materials; energy efficiency; clinker substitution; waste heat recovery and newer technologies. This roadmap sets out one pathway by which the Indian cement industry can reach its targets to improve energy efficiency and reduce CO2 emissions by 2050, thereby laying the foundation for low-carbon growth in the years beyond. The Technology Roadmap: Low-Carbon Technology for the Indian Cement Industry builds on the global IEA technology roadmap for the cement sector developed by the IEA and the World Business Council for Sustainable Development’s Cement Sustainability Initiative. It outlines a possible transition path for the Indian cement industry to reduce its direct CO2 emissions intensity to 0.35 tCO2/t cement and support the global goal of halving CO2 emissions by 2050.

  11. Idaho National Engineering Laboratory High-Level Waste Roadmap. Revision 2

    Energy Technology Data Exchange (ETDEWEB)

    1993-08-01

    The Idaho National Engineering Laboratory (INEL) High-Level Waste (HLW) Roadmap takes a strategic look at the entire HLW life-cycle starting with generation, through interim storage, treatment and processing, transportation, and on to final disposal. The roadmap is an issue-based planning approach that compares ``where we are now`` to ``where we want and need to be.`` The INEL has been effectively managing HLW for the last 30 years. Calcining operations are continuing to turn liquid HLW into a more manageable form. Although this document recognizes problems concerning HLW at the INEL, there is no imminent risk to the public or environment. By analyzing the INEL current business operations, pertinent laws and regulations, and committed milestones, the INEL HLW Roadmap has identified eight key issues existing at the INEL that must be resolved in order to reach long-term objectives. These issues are as follows: A. The US Department of Energy (DOE) needs a consistent policy for HLW generation, handling, treatment, storage, and disposal. B. The capability for final disposal of HLW does not exist. C. Adequate processes have not been developed or implemented for immobilization and disposal of INEL HLW. D. HLW storage at the INEL is not adequate in terms of capacity and regulatory requirements. E. Waste streams are generated with limited consideration for waste minimization. F. HLW is not adequately characterized for disposal nor, in some cases, for storage. G. Research and development of all process options for INEL HLW treatment and disposal are not being adequately pursued due to resource limitations. H. HLW transportation methods are not selected or implemented. A root-cause analysis uncovered the underlying causes of each of these issues.

  12. Instrumentation, Controls, and Human-Machine Interface Technology Development Roadmap in Support of Grid Appropriate Reactors

    Energy Technology Data Exchange (ETDEWEB)

    Holcomb, David Eugene [ORNL; Upadhyaya, Belle R. [University of Tennessee, Knoxville (UTK); Kisner, Roger A [ORNL; O' Hara, John [Brookhaven National Laboratory (BNL); Quinn, Edward L. [Longenecker & Associates; Miller, Don W. [Ohio State University

    2009-01-01

    Grid Appropriate Reactors (GARs) are a component of the U.S. Department of Energy s (DOE s) Global Nuclear Energy Partnership (GNEP) program. GARs have smaller output power (<~600 MWe), than those intended for deployment on large, tightly coupled grids. This smaller size is important in avoiding grid destabilization, which can result from having a large fraction of a grid s electrical generation supplied by a single source. GARs are envisioned to be deployed worldwide often in locations without extensive nuclear power experience. DOE recently sponsored the creation of an Instrumentation, Controls, and Human-Machine Interface (ICHMI) technology development roadmap emphasizing the specific characteristics of GARs [1]. This roadmapping effort builds upon and focuses the recently developed, more general nuclear energy ICHMI technology development roadmap [2]. The combination of the smaller plant size, smaller grids, and deployment in locations without extensive prior nuclear power experience presents particular infrastructure, regulation, design, operational, and safeguards challenges for effective GAR deployment. ICHMI technologies are central to efficient GAR operation and as such are a dimension of each of these challenges. Further, while the particular ICHMI technologies to be developed would be useful at larger power plants, they are not high-priority development items at the larger plants. For example, grid transient resilience would be a useful feature for any reactor/grid combination and indeed would have limited some recent blackout events. However, most large reactors have limited passive cooling features. Large plants with active safety response features will likely preserve trip preferential grid transient response. This contrasts sharply with GARs featuring passive shutdown cooling, which can safely support grid stability during large grid transients. ICHMI technologies ranging from alternative control algorithms to simplified human-interface system

  13. Technology Transfer and Commercialization

    Science.gov (United States)

    Martin, Katherine; Chapman, Diane; Giffith, Melanie; Molnar, Darwin

    2001-01-01

    During concurrent sessions for Materials and Structures for High Performance and Emissions Reduction, the UEET Intellectual Property Officer and the Technology Commercialization Specialist will discuss the UEET Technology Transfer and Commercialization goals and efforts. This will include a review of the Technology Commercialization Plan for UEET and what UEET personnel are asked to do to further the goals of the Plan. The major goal of the Plan is to define methods for how UEET assets can best be infused into industry. The National Technology Transfer Center will conduct a summary of its efforts in assessing UEET technologies in the areas of materials and emissions reduction for commercial potential. NTTC is assisting us in completing an inventory and prioritization by commercialization potential. This will result in increased exposure of UEET capabilities to the private sector. The session will include audience solicitation of additional commercializable technologies.

  14. Technology Roadmap. Energy Loss Reduction and Recovery in Industrial Energy Systems

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2004-11-01

    To help guide R&D decision-making and gain industry insights on the top opportunities for improved energy systems, ITP sponsored the Energy Loss Reduction and Recoveryin Energy Systems Roadmapping Workshopin April 2004 in Baltimore, Maryland. This Technology Roadmapis based largely on the results of the workshop and additional industrial energy studies supported by ITP and EERE. It summarizes industry feedback on the top opportunities for R&D investments in energy systems, and the potential for national impacts on energy use and the environment.

  15. A conceptual roadmap for setting up a system of units in the New SI context

    CERN Document Server

    Mari, Luca

    2016-01-01

    The definition of a system of units is analysed here as a structural problem, for which the physical theory provides the necessary conditions of realization but remains as backgrounder. The structurally more sophisticated option is provided by the so-called Global Constant Definitions, discussed in this paper through a conceptual roadmap intended to separate the components of the definitions based on theoretical foundation from those related to conventional features and, at the same time, to ensure the structural stability of the system and its partial modularity and therefore flexibility. The critical case of the so-called New SI is used as an illustration example.

  16. Arachnoid membrane: the first and probably the last piece of the roadmap.

    Science.gov (United States)

    Lü, Jian

    2015-03-01

    Most neurosurgical procedures could be performed noninvasively by working through the natural corridors provided by the subarachnoid cisterns. In consequence, the subarachnoid cisterns have been considered as the roadmaps for the microneurosurgeons. The concept and the contents of the cisterns have been well known and described, but the knowledge of the detailed anatomy of the arachnoid membranes, which are the real septa of the cisterns and provide the practical and important landmarks and planes for the dissections during the brain surgeries, is still lacking. The present article reviews the previous reports of the intracranial arachnoid membranes with a special emphasis on the microsurgical anatomy and the clinical significance.

  17. Solar Photovoltaic Hydrogen: The Technologies and Their Place in Our Roadmaps and Energy Economics

    Energy Technology Data Exchange (ETDEWEB)

    Kazmerski, L. L.; Broussard, K.

    2004-08-01

    Future solar photovoltaics-hydrogen systems are discussed in terms of the evolving hydrogen economy. The focus is on distributed hydrogen, relying on the same distributed-energy strengths of solar-photovoltaic electricity in the built environment. Solar-hydrogen residences/buildings, as well as solar parks, are presented. The economics, feasibility, and potential of these approaches are evaluated in terms of roadmap predictions on photovoltaic and hydrogen pathways-and whether solar-hydrogen fit in these strategies and timeframes. Issues with the ''hydrogen future'' are considered, and alternatives to this hydrogen future are examined.

  18. Solar photovoltaic hydrogen: the technologies and their place in our road-maps and energy economics

    Energy Technology Data Exchange (ETDEWEB)

    Kazmerski, L.L. [National Renewable Energy Laboratory, Golden, Colorado (United States); Broussard, K. [Southern Univ., Baton Rouge, LA (United States)

    2004-07-01

    Future solar photovoltaic-hydrogen systems are discussed in terms of the evolving hydrogen economy. The focus is on distributed hydrogen, relying on the same distributed-energy strengths of solar-photovoltaic electricity in the built environment. Solar-hydrogen residences/buildings, as well as solar parks, are presented. The economics, feasibility, and potential of these approaches are evaluated in terms of road-map predictions on photovoltaic and hydrogen pathways and whether solar-hydrogen fit in these strategies and time-frames. Issues with the ''hydrogen future'' are considered, and alternatives to this hydrogen future are examined. (authors)

  19. A Vision and Roadmap for Increasing User Autonomy in Flight Operations in the National Airspace

    Science.gov (United States)

    Cotton, William B.; Hilb, Robert; Koczo, Stefan; Wing, David

    2016-01-01

    The purpose of Air Transportation is to move people and cargo safely, efficiently and swiftly to their destinations. The companies and individuals who use aircraft for this purpose, the airspace users, desire to operate their aircraft according to a dynamically optimized business trajectory for their specific mission and operational business model. In current operations, the dynamic optimization of business trajectories is limited by constraints built into operations in the National Airspace System (NAS) for reasons of safety and operational needs of the air navigation service providers. NASA has been developing and testing means to overcome many of these constraints and permit operations to be conducted closer to the airspace user's changing business trajectory as conditions unfold before and during the flight. A roadmap of logical steps progressing toward increased user autonomy is proposed, beginning with NASA's Traffic Aware Strategic Aircrew Requests (TASAR) concept that enables flight crews to make informed, deconflicted flight-optimization requests to air traffic control. These steps include the use of data communications for route change requests and approvals, integration with time-based arrival flow management processes under development by the Federal Aviation Administration (FAA), increased user authority for defining and modifying downstream, strategic portions of the trajectory, and ultimately application of self-separation. This progression takes advantage of existing FAA NextGen programs and RTCA standards development, and it is designed to minimize the number of hardware upgrades required of airspace users to take advantage of these advanced capabilities to achieve dynamically optimized business trajectories in NAS operations. The roadmap is designed to provide operational benefits to first adopters so that investment decisions do not depend upon a large segment of the user community becoming equipped before benefits can be realized. The issues of

  20. Short communication: Effect of commercial or depurinized milk diet on plasma advanced oxidation protein products, cardiovascular markers, and bone marrow CD34+ stem cell potential in rat experimental hyperuricemia.

    Science.gov (United States)

    Kocic, Gordana; Sokolovic, Dusan; Jevtovic, Tatjana; Cvetkovic, Tatjana; Veljkovic, Andrej; Kocic, Hristina; Stojanovic, Svetlana; Jovanovic, Aneta; Jovanovic, Jelena; Zivkovic, Petar

    2014-11-01

    Cardiovascular repair and myocardial contractility may be improved by migration of bone marrow stem cells (BMSC) and their delivery to the site of injury, a process known as BMSC homing. The aim of our study was to examine the dietary effect of a newly patented depurinized milk (DP) that is almost free of uric acid and purine and pyrimidine compounds compared with a standard commercial 1.5% fat UHT milk diet or allopurinol therapy in rat experimental hyperuricemia. Bone marrow stem cell potential (BMCD34(+), CD34-postive bone marrow cells), plasma oxidative stress parameters [advanced oxidation protein products, AOPP) and thiobarbituric acid reactive substances (TBARS)], myocardial damage markers [creatine phosphokinase (CPK), aspartate aminotransferase (AST), and lactate dehydrogenase (LDH)], plasma cholesterol, and high-density lipoprotein cholesterol were investigated. The DP milk diet significantly increased the number of BMCD34(+) stem cells compared with commercial UHT milk. Allopurinol given alone also increased the number of BMCD34(+). Hyperuricemia caused a significant increase in all plasma enzyme markers for myocardial damage (CPK, LDH, and AST). A cardioprotective effect was achieved with allopurinol but almost equally with DP milk and more than with commercial milk. Regarding plasma AOPP, TBARS, and cholesterol levels, the most effective treatment was DP milk. In conclusion, the protective role of a milk diet on cardiovascular function may be enhanced through the new depurinized milk diet, which may improve cardiovascular system function via increased bone marrow stem cell regenerative potential, decreased plasma oxidative stress parameters, and decreased levels of myocardial damage markers and cholesterol. New dairy technology strategies focused on eliminating harmful milk compounds should be completely nontoxic. Novel milk products should be tested for their ability to improve tissue repair and function.

  1. FY 2000 report on the results of development of technology for commercializing high-efficiency fuel cell systems. Development of technology for commercializing high-efficiency fuel cell systems (Development of hydrogen separation type reforming technology); 2000 nendo kokoritsu nenryo denchi system jitsuyoka gijutsu kaihatsu seika hokokusho. Suiso bunrigata kaishitsu gijutsu kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-03-01

    Described herein are the FY 2000 results of development of new hydrogen production technology using natural gas as the feedstock, for promotion of commercializing high-efficiency fuel cell systems. The hydrogen separation type reforming system is composed of a reformer for producing and purifying hydrogen, and hydrogen suction unit for separating hydrogen produced. The reformer itself can produce pure hydrogen, because the hydrogen permeation membrane, provided in the reforming catalyst bed, can purify hydrogen selectively separated from the reformer gas. The remaining reformer off gas is burned with air to generate heat for the reforming reactions. This reforming process can produce as much hydrogen as does the conventional process at lower temperature, around 500 degrees C versus 800 degrees C needed by the conventional one, and hence more efficient, because hydrogen permeating through the membrane is discharged out of the system to allow the reactions to proceed without being limited by the chemical equilibrium. For development of membrane module manufacturing technology, the prototype membranes are prepared and their performances are evaluated. They are also incorporated in the test reformer to investigate the module performance and interactions between the membrane and reformer structure. Also described are improvement of efficiency of the hydrogen separation type reformer and development of the demonstration system. (NEDO)

  2. Commercial formalin substitutes for histopathology

    DEFF Research Database (Denmark)

    Prentø, P; Lyon, H

    1997-01-01

    of protein and structural immobilization, quality of histology and cellular structure following routine dehydration and paraffin embedding, and performance as a fixative for immunohistochemistry. Furthermore, we evaluated the effects of the various fixatives on ultrastructure. Only buffered formalin......We compared the performance of six commercial fixatives proposed to be formalin substitutes with the performance of buffered formalin, Clarke's ethanol-acetic acid, and ethanol, using rat liver, small intestine, and kidney. We investigated the rate of penetration, mode of fixation, extent...... performed equally well on all tissues tested. While several of the commercial fixatives appeared to preserve liver tissue at 200x, the preservation of kidney, intestinal villi, and smooth muscle was unacceptable. Histological distortion, cell shrinkage and vacuolization were prominent when the substitutes...

  3. Beyond the surface atlas: A roadmap and gazetteer for surface symmetry and structure

    Science.gov (United States)

    Jenkins, Stephen J.; Pratt, Stephanie J.

    2007-10-01

    Throughout the development of single-crystal surface science, interest has predominantly focussed on the high-symmetry planes of crystalline materials, which typically present simple stable structures with small primitive unit cells. This concentration of effort has rapidly and substantially advanced our understanding of fundamental surface phenomena, and provides a sound basis for detailed study of more complex planes. The intense current interest in these is partly motivated by their regular arrays of steps, kinks or other low-coordination structural features, whose properties are little understood and may mimic specific highly-reactive sites on dispersed nanoparticles. Furthermore, the lower symmetry of these planes may give rise to other equally interesting properties such as intrinsic chirality, with exciting potential applications in enantioselective heterogeneous catalysis, biosensors and surface magnetism. To aid exploration of this new territory for surface science requires a depth of understanding that goes beyond the character of individual surfaces to encompass the global relationships between all possible surfaces of a given material, both in their structure and in their symmetry. In this report we present a rigorous conceptual framework for ideal crystalline surfaces within which the symmetry and structure of all possible surface orientations are described. We illustrate the versatility of our generally-applicable approach by comparing fcc, bcc and hcp materials. The entire scheme naturally derives from the very simple basis that the fundamental distinction between symmetry and structure is paramount. Where symmetry is concerned, our approach recognises that the surface is not a two-dimensional (2D) object but actually a truncated three-dimensional (3D) one. We therefore derive a symmetry scheme specifically formulated for surfaces and naturally encompassing their chirality where necessary. Our treatment of surface structure, on the other hand

  4. Marketing mix - commercial gas

    Energy Technology Data Exchange (ETDEWEB)

    Ford, M.F.

    1975-07-01

    British Gas Corp. points out that a substantial increase in the use of gas in Great Britain's commercial energy market has occurred in the past 6 yr. Some of the newest applications of gas are in the areas of the cook/freeze system of preparing frozen foods in commercial catering, commissariats preparing in-flight food, and heating/cooling systems of large buildings. The variety of buildings and institutions using gas-fired systems indicates that, with the sensible pricing policies and the security of an indigenous fuel, the commercial market for gas will continue to develop for several years in Britain.

  5. A benefit to cost analysis of the effect of premilking teat hygiene on somatic cell count and intramammary infections in a commercial dairy herd.

    OpenAIRE

    1997-01-01

    A field trial was conducted to determine the effect of premilking teat disinfection (predipping) on several measures of mastitis in a commercial dairy farm where the predominant organisms isolated from intramammary infections were coagulase negative Staphylococcus spp. Cows were randomly assigned to a treated (predipped with 0.5% iodine germicide plus "good udder preparation") or a control group ("good udder preparation" alone). Sterile composite milk samples were collected at the initiation ...

  6. Common challenge, collaborative response: a roadmap for US-China cooperation on energy and climate change

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-01-15

    This Report which was produced in partnership between Asia Society's Center on U.S.-China Relations and Pew Center on Global Climate Change, in collaboration with The Brookings Institution, Council on Foreign Relations, National Committee on U.S.-China Relations, and Environmental Defense Fund presents both a vision and a concrete Roadmap for such Sino-U.S. collaboration. With input from scores of experts and other stakeholders from the worlds of science, business, civil society, policy, and politics in both China and the United States, the Report, or 'Roadmap', explores the climate and energy challenges facing both nations and recommends a concrete program for sustained, high-level, bilateral engagement and on-the-ground action. The Report recommends that, as a first step in forging this new partnership, the leaders of the two countries should convene a leaders summit as soon as practically possible following the inauguration of Barack Obama to launch a 'U.S.-China Partnership on Energy and Climate Change'. This presidential summit should outline a major plan of joint-action and empower relevant officials in each country to take the necessary actions to ensure its implementation. Priority areas of collaboration include: deploying low-emissions coal technologies; improving energy efficiency and conservation; developing an advanced electric grid; promoting renewable energy; and quantifying emissions and financing low-carbon technologies. 5 figs., 1 tab., 2 apps.

  7. A hands-on activity for teaching product-process matrix: roadmap and application

    Directory of Open Access Journals (Sweden)

    Luciano Costa Santos

    2014-08-01

    Full Text Available The product-process matrix is a well-known framework proposed by Hayes and Wheelwright (1979 that is commonly used to identify processes types and to analyze the alignment of these processes with the products of a company. For didactic purposes, the matrix helps undergraduates beginners from Production Engineering to understand the logic of production systems, providing knowledge that will be essential for various course subjects. Considering the high level of abstraction of the concepts underlying the product-process matrix, this paper presents a way to facilitate the learning of them through the application of a hands-on activity which relies on the active learning philosophy. The proposed dynamic uses colored plastic sheets and PVC pipes as main materials, differing from the original proposal of Penlesky and Treleven (2005 . In addition to presenting an extremely simple exercise, which encourages its application in the classroom, another contribution of this paper is to define a complete roadmap for conducting the activity. This roadmap describes the assembly of fictitious products in customization and standardization scenarios for the comparison of two processes types of product-process matrix, job shop and assembly line. The activity revealed very successful after its application to two groups of Production Engineering undergraduates, confirmed with positive feedback from the students surveyed.

  8. How to embrace uncertainty in participatory climate change risk management—A roadmap

    Science.gov (United States)

    Döll, Petra; Romero-Lankao, Patricia

    2017-01-01

    The Earth's future depends on how we manage the manifold risks of climate change (CC). It is state-of-the-art to assume that risk reduction requires participatory management involving a broad range of stakeholders and scientists. However, there is still little knowledge about the optimal design of participatory climate change risk management processes (PRMPs), in particular with respect to considering the multitude of substantial uncertainties that are relevant for PRMPs. To support the many local to regional PRMPs that are necessary for a successful global-scale reduction of CC risks, we present a roadmap for designing such transdisciplinary knowledge integration processes. The roadmap suggests ways in which uncertainties can be comprehensively addressed within a PRMP. We discuss the concept of CC risks and their management and propose an uncertainty framework that distinguishes epistemic, ontological, and linguistic uncertainty as well as ambiguity. Uncertainties relevant for CC risk management are identified. Communicative and modeling methods that support social learning as well as the development of risk management strategies are proposed for each of six phases of a PRMP. Finally, we recommend how to evaluate PRMPs as such evaluations and their publication are paramount for achieving a reduction of CC risks.

  9. Catalyzing strategic transformation to a low-carbon economy. A CCS roadmap for China

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Hengwei; Gallagher, Kelly Sims [Energy Technology Innovation Policy, Belfer Center for Science and International Affairs, John F. Kennedy School of Government, Harvard University, 79 John F. Kennedy Street, Cambridge, MA 02138 (United States)

    2010-01-15

    China now faces the three hard truths of thirsting for more oil, relying heavily on coal, and ranking first in global carbon dioxide (CO{sub 2}) emissions. Given these truths, two key questions must be addressed to develop a low-carbon economy: how to use coal in a carbon-constrained future? How to increase domestic oil supply to enhance energy security? Carbon Capture and Storage (CCS) may be a technological solution that can deal with today's energy and environmental needs while enabling China to move closer to a low-carbon energy future. This paper has been developed to propose a possible CCS roadmap for China. To develop the roadmap, we first explore major carbon capture opportunities in China and then identify critical CCS-enabling technologies, as well as analyze their current status and future prospects. We find that coal gasification or polygeneration in combination with CCS could be a nearly unbeatable combination for China's low-carbon future. Even without CCS, gasification offers many benefits: once coal is gasified into syngas, it can be used for many different purposes including for alternative fuels production, thereby increasing the domestic oil supply and the flexibility of the energy system. (author)

  10. Catalyzing strategic transformation to a low-carbon economy: A CCS roadmap for China

    Energy Technology Data Exchange (ETDEWEB)

    Liu Hengwei, E-mail: hengwei_liu@hks.harvard.ed [Energy Technology Innovation Policy, Belfer Center for Science and International Affairs, John F. Kennedy School of Government, Harvard University, 79 John F. Kennedy Street, Cambridge, MA 02138 (United States); Gallagher, Kelly Sims [Energy Technology Innovation Policy, Belfer Center for Science and International Affairs, John F. Kennedy School of Government, Harvard University, 79 John F. Kennedy Street, Cambridge, MA 02138 (United States)

    2010-01-15

    China now faces the three hard truths of thirsting for more oil, relying heavily on coal, and ranking first in global carbon dioxide (CO{sub 2}) emissions. Given these truths, two key questions must be addressed to develop a low-carbon economy: how to use coal in a carbon-constrained future? How to increase domestic oil supply to enhance energy security? Carbon Capture and Storage (CCS) may be a technological solution that can deal with today's energy and environmental needs while enabling China to move closer to a low-carbon energy future. This paper has been developed to propose a possible CCS roadmap for China. To develop the roadmap, we first explore major carbon capture opportunities in China and then identify critical CCS-enabling technologies, as well as analyze their current status and future prospects. We find that coal gasification or polygeneration in combination with CCS could be a nearly unbeatable combination for China's low-carbon future. Even without CCS, gasification offers many benefits: once coal is gasified into syngas, it can be used for many different purposes including for alternative fuels production, thereby increasing the domestic oil supply and the flexibility of the energy system.

  11. 100% Clean, Renewable Wind, Water, and Solar Roadmaps for 139 Countries of the World

    Science.gov (United States)

    Jacobson, M. Z.

    2015-12-01

    Significant prior research has focused on the health, climate, and other environmental and social impacts of gas and aerosol particle emissions from fossil fuel and biofuel combustion. Given the magnitude and costs of the impacts, large-scale conversions of these fuels to non-emitting sources of energy are warranted. This talk discusses technical and economic roadmaps to convert the energy infrastructures of each of 139 countries of the world to those powered by 100% non-emitting wind, water, and sunlight (WWS) for all purposes, namely electricity, transportation, heating/cooling, industry, and agriculture/forestry/fishing, after energy efficiency measures have been accounted for. These roadmaps are developed with a methodology similar to that recently derived for each of the 50 United States. Reliability of 100% WWS systems is crucial. To that end, results showing the ability of the United States to maintain a 100% reliable grid with a 100% WWS system are discussed as well. Please see http://web.stanford.edu/group/efmh/jacobson/Articles/I/WWS-50-USState-plans.html for more information.

  12. A Roadmap for Establishing Trust Management Strategy in E-Commerce Services Using Quality Based Assessment

    Directory of Open Access Journals (Sweden)

    Rath Jairak

    2014-10-01

    Full Text Available Trust has been reported as a key role in e-business, especially for a monetary based system like e-commerce. Therefore, many previous studies have been conducted to investigate the antecedents and consequences of consumer trust. But there has been little work done on establishing sensible solutions for leveraging consumer trust. Furthermore, previous studies in managerial trust have not demonstrated trust management that can illustrate a method to link their solutions with the consumers' point of view. In this paper, we therefore propose a practical roadmap for establishing trust management strategy that is consistent with consumer perceptions. Within this roadmap, firstly, a component extraction is performed on survey data in order to identify the quality criteria that actually impact buying decision process. Based on these criteria, the sensible factors for establishing trust and satisfaction are discovered from the regression analysis. Then, the prediction equations for trust and satisfaction are generated. After that the results of prediction equations are applied with a fuzzy linguistic approach in order to convert these results in linguistic terms. Finally, trust management strategy is established. By using our proposed method, website managers can identify which are the quality criteria that are consistent with their customer perceptions and they can use these criteria as a basis for improving trust and satisfaction in their websites.

  13. Commercial Manure Applicators

    Data.gov (United States)

    Iowa State University GIS Support and Research Facility — This layer represents the office location for Commercial Manure Services (CMS). They transport, handle, store or apply manure for a fee. The company must be licensed...

  14. Commercial Landing System

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Fisheries Statistics Division of the NOAA Fisheries has automated data summary programs that anyone can use to rapidly and easily summarize U.S. commercial...

  15. Technology Commercialization Program 1991

    Energy Technology Data Exchange (ETDEWEB)

    1991-11-01

    This reference compilation describes the Technology Commercialization Program of the Department of Energy, Defense Programs. The compilation consists of two sections. Section 1, Plans and Procedures, describes the plans and procedures of the Defense Programs Technology Commercialization Program. The second section, Legislation and Policy, identifies legislation and policy related to the Program. The procedures for implementing statutory and regulatory requirements are evolving with time. This document will be periodically updated to reflect changes and new material.

  16. Information for policy makers 2. Analysis of the EU's energy roadmap 2050 scenarios

    Energy Technology Data Exchange (ETDEWEB)

    Foerster, Hannah; Healy, Sean; Loreck, Charlotte; Matthes, Felix [Oeko-Institut e.V. - Institut fuer Angewandte Oekologie, Freiburg im Breisgau (Germany); Fischedick, Manfred; Lechtenboehmer, Stefan; Samadi, Sascha; Venjakob, Johannes [Wuppertal Institut (Germany)

    2012-05-15

    With growing concerns about climate change, energy import dependency and increasing fuel costs, a political consensus has formed in Europe in recent years about the need to transform the way we supply and consume energy. However, there is less political consensus on the specific steps that need to be taken in order to achieve a future sustainable energy system. Questions about which technologies should be used to what extent and how fast changes in the energy system should be instituted are being discussed on the European Union as well as on the Member State level. Energy scenarios are seen as a helpful tool to guide and inform these discussions. Several scenario studies on the European energy system have been released in recent years by stakeholders like environmental NGOs and industry associations. A number of these studies have recently been analysed by the Oeko-Institut and the Wuppertal Institute within an ongoing project commissioned by the Smart Energy for Europe Platform (SEFEF). The project aims to advance the debate on the decarbonisation of the energy system in the EU as well as its Member States during the course of 2012 and to make contributions to the scientific literature on this topic. Analysis within the project focuses on the development of the electricity system, as this system today is the main source for CO{sub 2} emissions and is widely regarded to be the key to any future decarbonisation pathway. The paper at hand summarises the analyses accomplished based on scenarios developed within the recently released Energy Roadmap 2050 of the European Union. The Roadmap explores different energy system pathways, which are compatible with the EU's long-term climate targets. It is a highly influential publication and will play a significant role in determining what will follow the EU's 2020 energy agenda. The Roadmap's analysis is currently discussed by EU and Member States policymakers as well as by stakeholders throughout Europe

  17. Comparative evaluation of the three different surface treatments - conventional, laser and Nano technology methods in enhancing the surface characteristics of commercially pure titanium discs and their effects on cell adhesion: An in vitro study.

    Science.gov (United States)

    Vignesh; Nayar, Sanjna; Bhuminathan; Mahadevan; Santhosh, S

    2015-04-01

    The surface area of the titanium dental implant materials can be increased by surface treatments without altering their shape and form, thereby increasing the biologic properties of the biomaterial. A good biomaterial helps in early cell adhesion and cell signaling. In this study, the commercially pure titanium surfaces were prepared to enable machined surfaces to form a control material and to be compared with sandblasted and acid-etched surfaces, laser treated surfaces and titanium dioxide (20 nm) Nano-particle coated surfaces. The surface elements were characterized. The biocompatibility was evaluated by cell culture in vitro using L929 fibroblasts. The results suggested that the titanium dioxide Nano-particle coated surfaces had good osteoconductivity and can be used as a potential method for coating the biomaterial.

  18. Roadmap for a Teacher-Student Data Link: Key Focus Areas to Ensure Quality Implementation. Data for Action

    Science.gov (United States)

    Data Quality Campaign, 2014

    2014-01-01

    Many states collect data on students and teachers, but linking teachers to students by course--the teacher-student data link (TSDL)--at the state level is critical to understanding the connection between student academic growth and teacher training, qualifications, and practice. This roadmap discusses the six key areas DQC recommends focusing on…

  19. A Review of Agile and Lean Manufacturing as Issues in Selected International and National Research and Development Programs and Roadmaps

    Science.gov (United States)

    Castro, Helio; Putnik, Goran D.; Shah, Vaibhav

    2012-01-01

    Purpose: The aim of this paper is to analyze international and national research and development (R&D) programs and roadmaps for the manufacturing sector, presenting how agile and lean manufacturing models are addressed in these programs. Design/methodology/approach: In this review, several manufacturing research and development programs and…

  20. Technological development for super-high efficiency solar cells. Survey on the commercialization on analysis; Chokokoritsu taiyo denchi no gijutsu kaihatsu. Jitsuyoka kaiseki ni kansuru chosa kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    Tatsuta, M. [New Energy and Industrial Technology Development Organization, Tokyo (Japan)

    1994-12-01

    This paper reports the survey results on analysis of super-high efficiency solar cells for practical use in fiscal 1994. (1) On the survey on crystalline compound solar cells, it was pointed out that the present study target is III-V compound semiconductor solar cell, and efficiencies of 36-39% are theoretically expected by use of two-junction cells. (2) On structure of super-high efficiency solar cells of 40%, selection of upper and lower cell materials for multi-junction cells, high-efficiency tandem Si solar cells, and the merit and possibility of light collection operation were surveyed, and their issues were discussed. (3) On physical properties of mixed crystalline semiconductors and characteristic evaluation of solar cells, impurities, trap center, minority carrier life, and applicability of supper lattice structure to high-efficiency solar cells were surveyed. (4) On fabrication technology of compound semiconductor solar cells, various problems of and approaches to electrode formation and antireflection film technologies, the meaning and issues of thin film substrate technology and continuous process, trial calculation of costs, safety, and resource problem were surveyed.