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Sample records for cell chp system

  1. CHP and CCHP Systems Today

    OpenAIRE

    Stojkov, Marinko; Hnatko, Emil; Kljajin, Milan; Živić, Marija; Hornung, Krunoslav

    2011-01-01

    The concept of the CCHP system (combined cooling, heating and power - combined cooling, heating and electricity generation) is described in this paper. The development of CCHP systems comes from the CHP system (combined heat and power generation), also known as cogeneration. CHP systems generate electricity from fuel combustion, heat as a by-product may contain even 60% to 80% of the total potential energy, and may be re-used for different applications. CHP is generally defined as the combine...

  2. Hybrid Solid Oxide Fuel Cell and Thermoelectric Generator for Maximum Power Output in Micro-CHP Systems

    DEFF Research Database (Denmark)

    Rosendahl, Lasse; Mortensen, Paw Vestergård; Enkeshafi, Ali A.

    2011-01-01

    One of the most obvious early market applications for thermoelectric generators (TEG) is decentralized micro combined heat and power (CHP) installations of 0.5 kWe to 5 kWe based on fuel cell technology. Through the use of TEG technology for waste heat recovery it is possible to increase the elec......One of the most obvious early market applications for thermoelectric generators (TEG) is decentralized micro combined heat and power (CHP) installations of 0.5 kWe to 5 kWe based on fuel cell technology. Through the use of TEG technology for waste heat recovery it is possible to increase...... the electricity production in micro-CHP systems by more than 15%, corresponding to system electrical efficiency increases of some 4 to 5 percentage points. This will make fuel cell-based micro-CHP systems very competitive and profitable and will also open opportunities in a number of other potential business...... and market segments which are not yet quantified. This paper quantifies a micro-CHP system based on a solid oxide fuel cell (SOFC) and a high-performance TE generator. Based on a 3 kW fuel input, the hybrid SOFC implementation boosts electrical output from 945 W to 1085 W, with 1794 W available for heating...

  3. Process Intensification in Fuel Cell CHP Systems, the ReforCELL Project

    Directory of Open Access Journals (Sweden)

    José Luis Viviente

    2016-10-01

    Full Text Available This paper reports the findings of a FP7/FCH JU project (ReforCELL that developed materials (catalysts and membranes and an advance autothermal membrane reformer for a micro Combined Heat and Power (CHP system of 5 kWel based on a polymer electrolyte membrane fuel cell (PEMFC. In this project, an active, stable and selective catalyst was developed for the reactions of interest and its production was scaled up to kg scale (TRL5 (TRL: Technology Readiness Level. Simultaneously, new membranes for gas separation were developed. In particular, dense supported thin palladium-based membranes were developed for hydrogen separation from reactive mixtures. These membranes were successfully scaled up to TRL4 and used in lab-scale reactors for fluidized bed steam methane reforming (SMR and autothermal reforming (ATR and in a prototype reactor for ATR. Suitable sealing techniques able to integrate the different membranes in lab-scale and prototype reactors were also developed. The project also addressed the design and optimization of the subcomponents (BoP for the integration of the membrane reformer to the fuel cell system.

  4. Experimental study and modelling of degradation phenomena in HTPEM fuel cell stacks for use in CHP systems

    DEFF Research Database (Denmark)

    Andreasen, Søren Juhl

    2009-01-01

    Degradation phenomena in HTPEM fuel cells for use in CHP systems were investigated experimentally and by modelling. It was found that the two main degradation mechanisms in HTPEM fuel cells are carbon corrosion and Pt agglomeration. On basis of this conclusion a mechanistic model, describing the...

  5. Experimental study and modeling of degradation phenomena in HTPEM fuel cell stacks for use in CHP systems

    DEFF Research Database (Denmark)

    Nielsen, Mads Pagh; Andreasen, Søren Juhl; Rasmussen, Peder Lund;

    2009-01-01

    Degradation phenomena in HTPEM fuel cells for use in CHP systems were investigated experimentally and by modeling. It was found that the two main degradation mechanisms in HTPEM fuel cells are carbon corrosion and Pt agglomeration. On basis of this conclusion a mechanistic model, describing the...

  6. Hybrid Solid Oxide Fuel Cell and Thermoelectric Generator for Maximum Power Output in Micro-CHP Systems

    Science.gov (United States)

    Rosendahl, L. A.; Mortensen, Paw V.; Enkeshafi, Ali A.

    2011-05-01

    One of the most obvious early market applications for thermoelectric generators (TEG) is decentralized micro combined heat and power (CHP) installations of 0.5 kWe to 5 kWe based on fuel cell technology. Through the use of TEG technology for waste heat recovery it is possible to increase the electricity production in micro-CHP systems by more than 15%, corresponding to system electrical efficiency increases of some 4 to 5 percentage points. This will make fuel cell-based micro-CHP systems very competitive and profitable and will also open opportunities in a number of other potential business and market segments which are not yet quantified. This paper quantifies a micro-CHP system based on a solid oxide fuel cell (SOFC) and a high-performance TE generator. Based on a 3 kW fuel input, the hybrid SOFC implementation boosts electrical output from 945 W to 1085 W, with 1794 W available for heating purposes.

  7. Cost targets for domestic fuel cell CHP

    Science.gov (United States)

    Staffell, I.; Green, R.; Kendall, K.

    Fuel cells have the potential to reduce domestic energy bills by providing both heat and power at the point of use, generating high value electricity from a low cost fuel. However, the cost of installing the fuel cell must be sufficiently low to be recovered by the savings made over its lifetime. A computer simulation is used to estimate the savings and cost targets for fuel cell CHP systems. Two pitfalls of this kind of simulation are addressed: the selection of representative performance figures for fuel cells, and the range of houses from which energy demand data was taken. A meta-study of the current state of the art is presented, and used with 102 house-years of demand to simulate the range of economic performance expected from four fuel cell technologies within the UK domestic CHP market. Annual savings relative to a condensing boiler are estimated at €170-300 for a 1 kWe fuel cell, giving a target cost of €350-625 kW -1 for any fuel cell technology that can demonstrate a 2.5-year lifetime. Increasing lifetime and reducing fuel cell capacity are identified as routes to accelerated market entry. The importance of energy demand is seen to outweigh both economic and technical performance assumptions, while manufacture cost and system lifetime are highlighted as the only significant differences between the technologies considered. SOFC are considered to have the greatest potential, but uncertainty in the assumptions used precludes any clear-cut judgement.

  8. Demand Response With Micro-CHP Systems

    OpenAIRE

    Houwing M.; Negenborn R.R.; De Schutter B.

    2011-01-01

    With the increasing application of distributed energy resources and novel information technologies in the electricity infrastructure, innovative possibilities to incorporate the demand side more actively in power system operation are enabled. A promising, controllable, residential distributed generation technology is a microcombined heat and power system (micro-CHP). Micro-CHP is an energy-efficient technology that simultaneously provides heat and electricity to households. In this paper, we ...

  9. Deployment of FlexCHP System

    Energy Technology Data Exchange (ETDEWEB)

    Cygan, David [Gas Technology Inst., Des Plaines, IL (United States)

    2015-11-01

    The Gas Technology Institute (GTI), along with its partner Integrated CHP Systems Corporation, has developed and demonstrated an Ultra-Low-Nitrogen Oxide (ULN) Flexible Combined Heat and Power (FlexCHP) system that packages a state-of-the-art Capstone C65 gas microturbine and Johnston PFXX100 boiler with an innovative natural gas-fired supplemental burner. Supplemental burners add heat as needed in response to facility demand, which increases energy efficiency, but typically raises exhaust NOx levels, degrading local air quality unless a costly and complicated catalytic treatment system is added. The FlexCHP system increases energy efficiency and achieves the 2007 California Air Resource Board (CARB) distributed generation emissions standards for Nitrogen oxides (NOx), Carbon Monoxide (CO), and Total Hydrocarbons (THC) without catalytic exhaust gas treatment. The key to this breakthrough performance is a simple and reliable burner design which utilizes staged combustion with engineered internal recirculation. This ULN burner system successfully uses turbine exhaust as an oxidizer, while achieving high efficiencies and low emissions. In tests at its laboratory facilities in Des Plaines, Illinois, GTI validated the ability of the system to achieve emissions of NOx, CO, and THC below the CARB criteria of 0.07, 0.10, and 0.02 lb/MW-h respectively. The FlexCHP system was installed at the field demonstration site, Inland Empire Foods, in Riverside, California to verify performance of the technology in an applied environment. The resulting Combined Heat and Power (CHP) package promises to make CHP implementation more attractive, mitigate greenhouse gas emissions, and improve the reliability of electricity supply.

  10. 330 kWe Packaged CHP System with Reduced Emissions

    Energy Technology Data Exchange (ETDEWEB)

    Plahn, Paul [Cummins Power Generation, Minneapolis, MN (United States); Keene, Kevin [Cummins Power Generation, Minneapolis, MN (United States); Pendray, John [Cummins Power Generation, Minneapolis, MN (United States)

    2015-03-31

    The objective of this project was to develop a flexible, 330 kWe packaged Combined Heat and Power (CHP) system that can be deployed to commercial and light industrial applications at a lower total cost of ownership than current CHP solutions. The project resulted in a CHP system that is easy to use and inexpensive to install, offering world class customer support, while providing a low-emissions, higher-efficiency internal combustion engine for a CHP system of this size.

  11. Modelling of a Solid Oxide Fuel Cell CHP System Coupled with a Hot Water Storage Tank for a Single Household

    Directory of Open Access Journals (Sweden)

    Vincenzo Liso

    2015-03-01

    Full Text Available In this paper a solid oxide fuel cell (SOFC system for cogeneration of heat and power integrated with a stratified heat storage tank is studied. The use of a storage tank with thermal stratification allows one to increase the annual operating hours of CHP: heat can be produced when the request is low (for instance during the night, taking advantage of thermal stratification to increases the heat recovery performance. A model of the SOFC system is presented to estimate the energy required to meet the average electric energy demand of the residence. Two fuels are considered, namely syngas produced by gasification and natural gas. The tank model considers the temperature gradients over the tank height. The results of the numerical simulation are used to size the SOFC system and storage heat tank to provide energy for a small household using two different fuels. In particular it was shown that in the case of syngas, due to larger system heat output, a larger tank volume was required in order to accumulate unused heat over the night. The detailed description of the tank model will be useful to energy system modelers when sizing hot water tanks. Problem formulation is reported also using a Matlab script.

  12. CHP Fuel Cell Durability Demonstration - Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Petrecky, James; Ashley, Christopher J

    2014-07-21

    Plug Power has managed a demonstration project that has tested multiple units of its high-temperature, PEM fuel cell system in micro-combined heat and power (μ-CHP) applications in California. The specific objective of the demonstration project was to substantiate the durability of GenSys Blue, and, thereby, verify its technology and commercial readiness for the marketplace. In the demonstration project, Plug Power, in partnership with the National Fuel Cell Research Center (NFCRC) at the University of California, Irvine (UCI), and Sempra, will execute two major tasks: • Task 1: Internal durability/reliability fleet testing. Six GenSys Blue units will be built and will undergo an internal test regimen to estimate failure rates. This task was modified to include 3 GenSys Blue units installed in a lab at UCI. • Task 2: External customer testing. Combined heat and power units will be installed and tested in real-world residential and/or light commercial end user locations in California.

  13. MICRO-CHP System for Residential Applications

    Energy Technology Data Exchange (ETDEWEB)

    Joseph Gerstmann

    2009-01-31

    This is the final report of progress under Phase I of a project to develop and commercialize a micro-CHP system for residential applications that provides electrical power, heating, and cooling for the home. This is the first phase of a three-phase effort in which the residential micro-CHP system will be designed (Phase I), developed and tested in the laboratory (Phase II); and further developed and field tested (Phase III). The project team consists of Advanced Mechanical Technology, Inc. (AMTI), responsible for system design and integration; Marathon Engine Systems, Inc. (MES), responsible for design of the engine-generator subsystem; AO Smith, responsible for design of the thermal storage and water heating subsystems; Trane, a business of American Standard Companies, responsible for design of the HVAC subsystem; and AirXchange, Inc., responsible for design of the mechanical ventilation and dehumidification subsystem.

  14. Micro-CHP Systems for Residential Applications

    Energy Technology Data Exchange (ETDEWEB)

    Timothy DeValve; Benoit Olsommer

    2007-09-30

    Integrated micro-CHP (Cooling, Heating and Power) system solutions represent an opportunity to address all of the following requirements at once: conservation of scarce energy resources, moderation of pollutant release into our environment, and assured comfort for home-owners. The objective of this effort was to establish strategies for development, demonstration, and sustainable commercialization of cost-effective integrated CHP systems for residential applications. A unified approach to market and opportunity identification, technology assessment, specific system designs, adaptation to modular product platform component conceptual designs was employed. UTRC's recommendation to U.S. Department of Energy is to go ahead with the execution of the proposed product development and commercialization strategy plan under Phase II of this effort. Recent indicators show the emergence of micro-CHP. More than 12,000 micro-CHP systems have been sold worldwide so far, around 7,500 in 2004. Market projections predict a world-wide market growth over 35% per year. In 2004 the installations were mainly in Europe (73.5%) and in Japan (26.4%). The market in North-America is almost non-existent (0.1%). High energy consumption, high energy expenditure, large spark-spread (i.e., difference between electricity and fuel costs), big square footage, and high income are the key conditions for market acceptance. Today, these conditions are best found in the states of New York, Pennsylvania, New Jersey, Wisconsin, Illinois, Indiana, Michigan, Ohio, New England states. A multiple stage development plan is proposed to address risk mitigation. These stages include concept development and supplier engagement, component development, system integration, system demonstration, and field trials. A two stage commercialization strategy is suggested based on two product versions. The first version--a heat and power system named Micro-Cogen, provides the heat and essential electrical power to the

  15. Modeling and simulation of a residential micro-CHP system based on HT-PEMFC technology

    DEFF Research Database (Denmark)

    Arsalis, Alexandros; Nielsen, Mads Pagh; Kær, Søren Knudsen

    2009-01-01

    Combined-heat-and-power (CHP) technology is a well known and proved method to produce simultaneously power and heat at high efficiencies. This can be further improved by the introduction of a novel micro-CHP residential system based on High Temperature-Proton Exchange Membrane Fuel Cell (HT...

  16. Micro-CHP Systems for Residential Applications

    Energy Technology Data Exchange (ETDEWEB)

    Timothy DeValve; Benoit Olsommer

    2007-09-30

    Integrated micro-CHP (Cooling, Heating and Power) system solutions represent an opportunity to address all of the following requirements at once: conservation of scarce energy resources, moderation of pollutant release into our environment, and assured comfort for home-owners. The objective of this effort was to establish strategies for development, demonstration, and sustainable commercialization of cost-effective integrated CHP systems for residential applications. A unified approach to market and opportunity identification, technology assessment, specific system designs, adaptation to modular product platform component conceptual designs was employed. UTRC's recommendation to U.S. Department of Energy is to go ahead with the execution of the proposed product development and commercialization strategy plan under Phase II of this effort. Recent indicators show the emergence of micro-CHP. More than 12,000 micro-CHP systems have been sold worldwide so far, around 7,500 in 2004. Market projections predict a world-wide market growth over 35% per year. In 2004 the installations were mainly in Europe (73.5%) and in Japan (26.4%). The market in North-America is almost non-existent (0.1%). High energy consumption, high energy expenditure, large spark-spread (i.e., difference between electricity and fuel costs), big square footage, and high income are the key conditions for market acceptance. Today, these conditions are best found in the states of New York, Pennsylvania, New Jersey, Wisconsin, Illinois, Indiana, Michigan, Ohio, New England states. A multiple stage development plan is proposed to address risk mitigation. These stages include concept development and supplier engagement, component development, system integration, system demonstration, and field trials. A two stage commercialization strategy is suggested based on two product versions. The first version--a heat and power system named Micro-Cogen, provides the heat and essential electrical power to the

  17. Heat Pumps in CHP Systems

    DEFF Research Database (Denmark)

    Ommen, Torben Schmidt

    were identified and compared based on a thermodynamic analysis. The operational performance of the configurations were investigated at both local and system level considering different DH network temperatures, different fuels and different production technologies in the DH network. The analysis show...... that three configurations are particular advantageous, whereas the two remaining configurations result in system performance close to or below what may be expected from an electric heater. One of the three advantageous configurations is required to be positioned at the location of the heat demand, whereas...... applicability of components causes a significantly increased cost at high temperature lifts, compared to the most competitive thermodynamic cycle. At high and medium temperature lifts cycle efficiencies of 45 - 50 % of the theoretical maximum (Lorenz cycle limit) can be achieved, whereas for low temperature...

  18. Rho family GTPase Chp/RhoV induces PC12 apoptotic cell death via JNK activation

    OpenAIRE

    Shepelev, Mikhail V; Chernoff, Jonathan; Korobko, Igor V

    2011-01-01

    Rho GTPases regulate numerous cellular processes including apoptosis. Chp/RhoV is an atypical Rho GTPase which functions are poorly understood. Here we investigated the role of Chp in regulation of cell viability using PC12 cells with inducible expression of Chp as a model. We found that expression of Chp results in apoptosis in PC12 cells. Chp-induced apoptosis was accompanied by activation of JNK signaling and both death receptor-mediated and mitochondrial apoptotic pathways as justified by...

  19. Expanders for micro-CHP systems with organic Rankine cycle

    International Nuclear Information System (INIS)

    The continual increases in global energy demand and greenhouse gas emissions call for more and more utilisation of sustainable energy sources, such as solar energy, biomass energy, and waste heat. Solar thermal energy, the heat of biomass combustion and waste heat may be used to drive a combined heat and power (CHP) system. In recent years, several micro-CHP systems with organic Rankine cycle (ORC) suitable for domestic applications (1-10 kWe) driven by solar thermal, biomass-fired boilers and waste heat resources have been investigated. These ORC-based micro-CHP systems have lower operation pressures and temperatures compared to conventional steam-Rankine cycle CHP systems and hence safer for household applications. However, the lack of commercially available expanders applicable to ORC-based micro-CHP systems has hindered the development of these novel CHP systems. This paper summarizes the findings of the market research for the expanders and discusses the selection and choices of the expanders for ORC-based micro-CHP systems. The working principles and the characteristics of several kinds of expanders, including turbine expanders (i.e., turboexpander), screw expanders, scroll expanders and vane expanders, are introduced and evaluated. - Highlights: → Expanders are vital to ORC-based micro-CHP but not yet commercially available. → Selection and choices of the expanders for 1-10 kWe micro-CHP are discussed. → Vane expanders modified from vane-type air motors have been applied by the authors. → Scroll expanders and vane expanders are likely the good choices for 1-10 kWe micro-CHP.

  20. CFD simulation of Pd-based membrane reformer when thermally coupled within a fuel cell micro-CHP system

    Energy Technology Data Exchange (ETDEWEB)

    Roses, Leonardo; Manzolini, Giampaolo; Campanari, Stefano [Politecnico di Milano, Dipartimento di Energia, Via Lambruschini 4, 20156 Milano (Italy)

    2010-11-15

    In this work, a bi-dimensional CFD simulation investigates a fuel processor for hydrogen production from natural gas or biogas composed by a steam methane reformer coupled with a palladium-based hydrogen permeable membrane, the so-called ''membrane reformer'' (MREF). The heat required for the endothermic reforming reaction taking place on the MREF is supplied by a stream of hot gas coming from an external source, typically represented by a combustor burning the unconverted fuel and the unpermeated hydrogen. The resulting fuel processor arrangement, which has already been simulated by the point of view of energy and mass balances, may achieve a very high efficiency and is particularly suited for integration with fuel cells. The interest on this configuration relies on the possibility to implement this technology within a PEMFC-based micro-cogenerator (also micro-Combined Heat and Power, or m-CHP) with a net electrical power output in a range of 1-2 kW. In particular, the work focuses on the temperature profiles along the membrane, which should be kept as close as possible to 600 C to favourite permeation and avoid any damages, and examines the advantages of hot gas on co-current direction vs. counter-current with respect to the reformer flux direction. (author)

  1. A case study analysis of system efficiency, viability and energy values of SOFC based fuel cell Micro-CHP for office buildings

    OpenAIRE

    Tesfai, Alem; Mylona, A.; Connor, Paul Alexander; Cassidy, Mark; Irvine, John Thomas Sirr

    2015-01-01

    The built environment is a large contributor to the greenhouse gas emissions. The first step in tackling environmental impact and fuel cost reduction is the minimization of energy losses through introduction of new and more efficient energy conversion technologies. In this study, the potential application of fuel cell micro-CHP in a typical office building is investigated. A 1.5 kWel fuel cell micro-CHP has been installed in an office building at CIBSE headquarters (HQ). The unit converts nat...

  2. Designing and control of a SOFC micro-CHP system

    DEFF Research Database (Denmark)

    Liso, Vincenzo

    component for steady-state operation were developed. System concepts and key performance parameters were identified. The models were used to evaluate optimal cell-stack power output, the impact of cell operating and design parameters, thermal energy recovery, system process design, and operating strategy...... results. Also, predominant modes of catalytic reforming were identified and modeled. System design evaluations reveal that methane-fueled SOFC systems demonstrate the highest electrical efficiency when coupled with a steam reformer process. The use of recycled cell exhaust gases in process design is found......-to-power ratio demonstrated in this study makes the SOFC-based micro-CHP systems a promising technology for energy conversion when compared to other well established technologies such as internal combustion engines or sterling engines. In particular, the range of heat-to-power ratio for the SOFC-based micro...

  3. Expanders for micro-CHP systems with organic Rankine cycle

    OpenAIRE

    Qiu, Guoquan; Liu, Hao; Riffat, Saffa

    2011-01-01

    Abstract The continual increases in global energy demand and greenhouse gas emissions call for more and more utilisation of sustainable energy sources, such as solar energy, biomass energy, and waste heat. Solar thermal energy, the heat of biomass combustion and waste heat may be used to drive a combined heat and power (CHP) system. In recent years, several micro-CHP systems with organic Rankine cycle (ORC) suitable for domestic applications (1-10kWe) driven by solar thermal, bioma...

  4. Procuring Stationary Fuel Cells For CHP: A Guide for Federal Facility Decision Makers

    Energy Technology Data Exchange (ETDEWEB)

    Stinton, David P [ORNL; McGervey, Joseph [SRA International, Inc.; Curran, Scott [ORNL

    2011-11-01

    Federal agency leaders are expressing growing interest in using innovative fuel cell combined heat and power (CHP) technology at their sites, motivated by both executive branch sustainability targets and a desire to lead by example in the transition to a clean energy economy. Fuel cell CHP can deliver reliable electricity and heat with 70% to 85% efficiency. Implementing this technology can be a high efficiency, clean energy solution for agencies striving to meet ambitious sustainability requirements with limited budgets. Fuel cell CHP systems can use natural gas or renewable fuels, such as biogas. Procuring Stationary Fuel Cells for CHP: A Guide for Federal Facility Decision Makers presents an overview of the process for planning and implementing a fuel cell CHP project in a concise, step-by-step format. This guide is designed to help agency leaders turn their interest in fuel cell technology into successful installations. This guide concentrates on larger (100 kW and greater) fuel cell CHP systems and does not consider other fuel cell applications such as cars, forklifts, backup power supplies or small generators (<100 kW). Because fuel cell technologies are rapidly evolving and have high up front costs, their deployment poses unique challenges. The electrical and thermal output of the CHP system must be integrated with the building s energy systems. Innovative financing mechanisms allow agencies to make a make versus buy decision to maximize savings. This guide outlines methods that federal agencies may use to procure fuel cell CHP systems with little or no capital investment. Each agency and division, however, has its own set of procurement procedures. This guide was written as a starting point, and it defers to the reader s set of rules if differences exist. The fuel cell industry is maturing, and project developers are gaining experience in working with federal agencies. Technology improvements, cost reductions, and experienced project developers are making

  5. Modeling work of a small scale gasifier/SOFC CHP system

    Energy Technology Data Exchange (ETDEWEB)

    Liu, M.; Aravind, P.V.; Qu, Z.; Woudstra, N.; Verkooijen, A.H.M. [Delft University of Technology (Netherlands). Dept. of Mechanical Engineering], Emails: ming.liu@tudelft.nl, p.v.aravind@tudelft.nl, z.qu@tudelft.nl, n.woudstra@tudelft.nl, a. h. m. verkooijen@tudelft.nl; Cobas, V.R.M. [Federal University of Itajuba (UNIFEI), Pinheirinhos, MG (Brazil). Dept. of Mechanical Engineering], E-mail: vlad@unifei.edu.br

    2009-07-01

    For a highly efficient biomass gasification/Solid Oxide Fuel Cell (SOFC) Combined Heat and Power (CHP) generation system, the gasifier, the accompanying gas cleaning technologies and the CHP unit must be carefully designed as an integrated unit. This paper describes such a system involving a two-stage fixed-bed down draft gasifier, a SOFC CHP unit and a gas cleaning system. A gas cleaning system with both low temperature and high temperature sections is proposed for coupling the gasifier and the SOFC. Thermodynamic modeling was carried out for the gasifier/SOFC system with the proposed gas cleaning system. The net AC electrical efficiency of this system is around 30% and the overall system efficiency is around 60%. This paper also describes various exergy losses in the system and the future plans for integrated gasifier-GCU-SOFC experiments from which the results will be used to validate the modeling results of this system. (author)

  6. Monitoring and Commissioning Verification Algorithms for CHP Systems

    Energy Technology Data Exchange (ETDEWEB)

    Brambley, Michael R.; Katipamula, Srinivas; Jiang, Wei

    2008-03-31

    This document provides the algorithms for CHP system performance monitoring and commissioning verification (CxV). It starts by presenting system-level and component-level performance metrics, followed by descriptions of algorithms for performance monitoring and commissioning verification, using the metric presented earlier. Verification of commissioning is accomplished essentially by comparing actual measured performance to benchmarks for performance provided by the system integrator and/or component manufacturers. The results of these comparisons are then automatically interpreted to provide conclusions regarding whether the CHP system and its components have been properly commissioned and where problems are found, guidance is provided for corrections. A discussion of uncertainty handling is then provided, which is followed by a description of how simulations models can be used to generate data for testing the algorithms. A model is described for simulating a CHP system consisting of a micro-turbine, an exhaust-gas heat recovery unit that produces hot water, a absorption chiller and a cooling tower. The process for using this model for generating data for testing the algorithms for a selected set of faults is described. The next section applies the algorithms developed to CHP laboratory and field data to illustrate their use. The report then concludes with a discussion of the need for laboratory testing of the algorithms on a physical CHP systems and identification of the recommended next steps.

  7. Local CHP Plants between the Natural Gas and Electricity Systems

    DEFF Research Database (Denmark)

    Bregnbæk, Lars; Schaumburg-Müller, Camilla

    2005-01-01

    , and they contribute significantly to the electricity production. CHP is, together with the wind power, the almost exclusive distributed generation in Denmark. This paper deals with the CHP as intermediary between the natural gas system and the electricity system. In particular, the relationship between the peak hour......Local combined heat and power (CHP) plants in Denmark constitute an important part of the national energy conversion capacity. In particular they supply a large share of the district heating networks with heat. At the same time they are important consumers as seen from the gas network system...... characteristics of the electricity and gas systems will be investigated. The point is here that the two systems will tend to have peak demand during the same hours. This is the typical situation, since load is high during the same hours of the day and of the year. Moreover, the random variations in the load...

  8. Developing a Model for a CHP System with Storage

    Directory of Open Access Journals (Sweden)

    M. Abunku

    2016-04-01

    Full Text Available A model for a Combined Heat and Power (CHP system developed using Matlab is presented in this project. The model developed includes sub-models of Internal Combustion Engine (ICE and generator, electrical and thermal storage systems, and power converters (rectifier and inverter. The model developed is able to simulate the performance of a CHP system when supplying user load. The battery electrical storage system is modelled and used as the electrical storage for this project, and the water storage tank is modelled and used as thermal storage. The project presents the model developed, and the results of the analysis done on the model. The model considered only heat from engine cooling, which is used to heat water to supply the DHW (District Hot Water needs of the user. The results show that by the addition of storage to the CHP system, the overall system efficiency is increased by 32% indicating that the model developed is reliable, and the project is a feasible one

  9. Designing and optimization of a micro CHP system based on Solid Oxide Fuel Cell with different fuel processing technologies

    DEFF Research Database (Denmark)

    Liso, Vincenzo; Nielsen, Mads Pagh; Kær, Søren Knudsen

    2009-01-01

    The development of fuel cell technologies offers the opportunity to achieve significant improvements in energy conversion efficiencies at many scales. The high operating temperature (700-1000 Celsius) of Solid Oxide Fuel Cells (SOFC) has a number of consequences, the most important of which...

  10. Space Heating Load Estimation Procedure for CHP Systems sizing

    Science.gov (United States)

    Vocale, P.; Pagliarini, G.; Rainieri, S.

    2015-11-01

    Due to its environmental and energy benefits, the Combined Heat and Power (CHP) represents certainly an important measure to improve energy efficiency of buildings. Since the energy performance of the CHP systems strongly depends on the fraction of the useful cogenerated heat (i.e. the cogenerated heat that is actually used to meet building thermal demand), in building applications of CHP, it is necessary to know the space heating and cooling loads profile to optimise the system efficiency. When the heating load profile is unknown or difficult to calculate with a sufficient accuracy, as may occur for existing buildings, it can be estimated from the cumulated energy uses by adopting the loads estimation procedure (h-LEP). With the aim to evaluate the useful fraction of the cogenerated heat for different operating conditions in terms of buildings characteristics, weather data and system capacity, the h-LEP is here implemented with a single climate variable: the hourly average dry- bulb temperature. The proposed procedure have been validated resorting to the TRNSYS simulation tool. The results, obtained by considering a building for hospital use, reveal that the useful fraction of the cogenerated heat can be estimated with an average accuracy of ± 3%, within the range of operative conditions considered in the present study.

  11. A study on electricity export capability of the μCHP system with spot price

    DEFF Research Database (Denmark)

    You, Shi; Træholt, Chresten; Poulsen, Bjarne

    2009-01-01

    When a number of muCHP systems are aggregated as a virtual power plant (VPP), they will be able to participate in the electricity wholesale market with no discrimination compared to conventional large power plants. Hence, this paper investigates the electricity export capability of the muCHP system...... when the electricity buyback price is given at a value equalizing the dynamic spot price. A muCHP system is modeled with optimized generation, and the marginal price of electricity export for such system is explained. A sensitivity analysis of several key factors, e.g. fuel price, heat to power ratio...... of the muCHP unit, which influence the export capability of muCHP system, is firstly carried out in the intraday case study, followed by the annual case study which explores the annual system performance. The results show that the electricity export capability of a muCHP system is closely related to its...

  12. Performance of a solid oxide fuel cell CHP system coupled with a hot water storage tank for single household

    DEFF Research Database (Denmark)

    Liso, Vincenzo; Zhao, Yingru; Yang, Wenyuan

    2014-01-01

    household using two different fuels. In particular it was shown that in the case of syngas, due to larger system heat output, a larger tank volume was required in order to accumulate unused heat over the night. The detailed description of the tank model will be useful to energy system modelers when sizing...

  13. Modelling of a solid oxide fuel cell CHP system coupled with a hot water storage tank for a single household

    DEFF Research Database (Denmark)

    Liso, Vincenzo; Zhao, Yingru; Yang, Wenyuan;

    2015-01-01

    is low (for instance during the night), taking advantage of thermal stratification to increases the heat recovery performance. A model of the SOFC system is presented to estimate the energy required to meet the average electric energy demand of the residence. Two fuels are considered, namely syngas...... that in the case of syngas, due to larger system heat output, a larger tank volume was required in order to accumulate unused heat over the night. The detailed description of the tank model will be useful to energy system modelers when sizing hot water tanks. Problem formulation is reported also using a Matlab...

  14. Optimal design and operation of a syngas-fuelled SOFC micro CHP system for residential applications in different climate zones in China

    DEFF Research Database (Denmark)

    Yang, Wenyuan; Zhao, Yingru; Liso, Vincenzo;

    2014-01-01

    Fuel cell based micro-CHP systems are expected to be one of the most promising technologies for implementation in the residential sector. Since the design and operation of such CHP systems are greatly dependent upon the seasonal atmospheric conditions, it is important to evaluate their performance...... under difference climate conditions to ensure that it is well matched with the local heat-to-power ratio. The aim of this study is to investigate the optimal design and operation of a syngas-fuelled SOFC micro-CHP system for small households located in five different climate zones in China. The ability...... to determine the optimal match between the energy demand of the household for different climates across China and the energy supply of the micro-CHP during the whole year. Moreover, criteria for sizing the system components of the micro-CHP are specifically addressed. The developed methodology can be applied...

  15. Assessment of the implementation issues for fuel cells in domestic and small scale stationary power generation and CHP applications

    Energy Technology Data Exchange (ETDEWEB)

    Graham, G.; Cruden, A.; Hart, J.

    2002-07-01

    This report discusses implementation issues associated with the use of fuel cells in <10 kW domestic, small-scale power generation and combined heat and power (CHP) operations in the UK. The report examines the key issues (fuel cell system standards and certification, fuel infrastructure, commercial issues and competing CHP technologies), before discussing non-technical issues including finance, ownership, import and export configuration, pricing structure, customer acceptability, installation, operation and training of servicing and commissioning personnel. The report goes on to discuss market and technical drivers, grid connection issues and solutions, operations and maintenance. Recommendations for the future are made.

  16. Power and heat from CHP fuel cell systems in the basement. Testing of fuel cell-driven heating systems; Kleinkraftwerke im Keller sorgen fuer Strom und Waerme. Brennstoffzellen-Heizgeraete in der Erprobung

    Energy Technology Data Exchange (ETDEWEB)

    Tschaetsch, H.U.

    2002-03-25

    The article discusses important aspects of a joint project funded by industry, utilities and the State Government of North Rhine-Westphalia. The field test results, the performance and engineering data of the innovative energy conversion and storage system based on the fuel cell-driven CHP technology for on-site power and heat production for a multi-family house are described in detail. (orig./CB) [German] Die Entwicklung der Brennstoffzellen-Technologie fuer die dezentrale Strom- und Waermeversorgung ist in einer entscheidenden Phase. In einem Mehrfamilienhaus in Gelsenkirchen begann im Januar 2002 der erste Praxistest eines Vaillant Brennstoffzellen-Heizgeraetes (BZH), das mit einem Kostenaufwand von rd. 2,2 Mio. Euro entwickelt wurde. Die Projektpartner Vaillant GmbH, Remscheidt, Ruhrgas AG, Essen, Eon Engineering GmbH, Gelsenkirchen, ELE Emscher Lippe Energie GmbH, Gelsenkirchen, und EUS - Gesellschaft fuer innovative Energieumwandlung und -speicherung mbH., Gelsenkirchen, wollen mit dem vom Land Nordrhein-Westfalen (NRW) mit insgesamt 800 000 Euro unterstuetzten Feldtest zeigen, dass die einzelnen Komponenten Brennstoffzelle, Warmwasserspeicher und Zusatzheizgeraet ueber einen Energiemanager (Prozesssteuerung) kostenoptimal zusammenarbeiten koennen. (orig.)

  17. Demand Response With Micro-CHP Systems

    NARCIS (Netherlands)

    Houwing, M.; Negenborn, R.R.; De Schutter, B.

    2011-01-01

    With the increasing application of distributed energy resources and novel information technologies in the electricity infrastructure, innovative possibilities to incorporate the demand side more actively in power system operation are enabled. A promising, controllable, residential distributed genera

  18. Modeling and optimization of a 1 kWe HT-PEMFC-based micro-CHP residential system

    DEFF Research Database (Denmark)

    Arsalis, Alexandros; Nielsen, Mads Pagh; Kær, Søren Knudsen

    2012-01-01

    A high temperature-proton exchange membrane (HT-PEMFC)-based micro-combined-heat-and-power (CHP) residential system is designed and optimized, using a genetic algorithm (GA) optimization strategy. The proposed system consists of a fuel cell stack, steam methane reformer (SMR) reactor, water gas...... shift (WGS) reactor, heat exchangers, and other balance-of-plant (BOP) components. The objective function of the single-objective optimization strategy is the net electrical efficiency of the micro-CHP system. The implemented optimization procedure attempts to maximize the objective function...

  19. CHP efficiency of a 2000 × CPV system with reflective optics

    Science.gov (United States)

    Bonsignore, Gaetano; Gallitto, Aurelio Agliolo; Agnello, Simonpietro; Barbera, Marco; Gelardi, Franco M.; Sciortino, Luisa; Collura, Alfonso; Cicero, Ugo Lo; Milone, Sergio; Montagnino, Fabio M.; Paredes, Filippo; Cannas, Marco

    2015-09-01

    In this work we have developed a combined heat and power (CHP) prototype that operates at 2000 × concentration based on reflective optics. The receiver consists of a InGaP/InGaAs/Ge triple-junction solar cell in thermal contact with an aluminium heat sink driving a forced water flow. This CHP system was tested both indoor (DNI of 650 W/m2) and outdoor (DNI of 900 W/m2) under different conditions of fluid parameters as the flow rate (ranging from 0.2 liters/min to 1.2 liters/min) and temperature (ranging from 25 °C to 60 °C). Electrical and thermal power were determined by acquiring IV curves and by measuring the heat subtracted from the cell while it delivered the maximum electrical power, respectively. The obtained results demonstrate that this CHP system achieves a total efficiency of about 80%, shared between the electrical (30%) and the thermal one (50%).

  20. SOFC/TEG hybrid mCHP system. Final report

    Energy Technology Data Exchange (ETDEWEB)

    2012-03-15

    The starting point for this project have been the challenge has been to develop a cost effective solution with long term stability. This is where a focused effort in a strong consortium covering material research, module development and manufacture as well as device design and optimization can make a real difference. In March 2010 the SOFTEG phase II project was initiated and a cooperation organization was established to implement the project as a development and demonstration project involving the staff from all project partners. The project is now completed with excellent and documented outcome. The final results by Alpcon have been demonstration as a TEG-based mCHP system calls CHP Dual Engine Power System, which will be applicable as both a standalone TEG-CHP hybrid system, but also as an auxiliary power unit and power booster for the SOFC system. However the SOFC system cannot cover the household's heat demand alone so it is necessary to combine a SOFC system together with a water heater/boiler system to cover the peak heat demand of a residential house or a complex building. The SOFTEG project partners achieved significant results that mainly can be outlined as following: 1) University of Aarhus has improved the thermal stability of ZnSb by optimizing the concentration of Nano composite material. 2) The grain size and its influence on the sintering process by spark plasma method are investigated by Aarhus University, but further work seems to be necessary. 3) The TE material is going to commercialization by Aarhus University. 4) Aalborg University has prepared simulation tools for complex thermoelectric simulation in non-steady state condition. 5) The new type DCDC interleaved converter using the MPPT system for optimal power tracing is designed, build and tested by Aalborg University in cooperation with Alpcon. This task is included overall system design, control system implementation and power electronic control design. 6) Full scale practical

  1. Development of Next Generation micro-CHP System

    DEFF Research Database (Denmark)

    Arsalis, Alexandros

    is applied to minimize the annual cost of the HEN (Heat Exchanger Network). The results obtained throughout this research work indicate the high potential of the proposed micro-CHP system, since net electrical efficiencies of up to 44% were reached, which are far and away higher than heat engine...... topics: (a) Modeling, simulation and validation of the system in LabVIEW environment to provide the ability of Data Acquisition of actual components, and thereby more realistic design in the future; (b) Modeling, parametric study, and sensitivity analysis of the system in EES (Engineering Equation Solver......). The parametric study is conducted to determine the most viable system/component design based on maximizing total system efficiency; (c) An improved operational strategy is formulated and applied in an attempt to minimize operational implications, experienced when using conventional operational strategies; (d...

  2. Modeling and off-design performance of a 1 kWe HT-PEMFC (high temperature-proton exchange membrane fuel cell)-based residential micro-CHP (combined-heat-and-power) system for Danish single-family households

    DEFF Research Database (Denmark)

    Arsalis, Alexandros; Nielsen, Mads Pagh; Kær, Søren Knudsen

    2011-01-01

    A novel proposal for the modeling and operation of a micro-CHP (combined-heat-and-power) residential system based on HT-PEMFC (High Temperature-Proton Exchange Membrane Fuel Cell) technology is described and analyzed to investigate its commercialization prospects. An HT-PEMFC operates at elevated...

  3. A study on electricity export capability of the μCHP system with spot price

    OpenAIRE

    You, Shi; Træholt, Chresten; Poulsen, Bjarne

    2009-01-01

    When a number of muCHP systems are aggregated as a virtual power plant (VPP), they will be able to participate in the electricity wholesale market with no discrimination compared to conventional large power plants. Hence, this paper investigates the electricity export capability of the muCHP system when the electricity buyback price is given at a value equalizing the dynamic spot price. A muCHP system is modeled with optimized generation, and the marginal price of electricity export for such ...

  4. Analysis of the location for peak heating in CHP based combined district heating systems

    International Nuclear Information System (INIS)

    Combined heat and power (CHP) is the main technology for providing the base load of district heating in China. However, CHP is not efficient for providing the peak load; instead, a peak boiler with high efficiency could be used to compensate the peak load. This paper studies how the location of the peak boiler can affect the energy efficiency and economic performance of such CHP based combined district heating system. Firstly, the connection mode and the control strategy for different peak heating locations are analyzed. Then the effect of the peak boiler's location on the initial investment of the network and the cost for distributing heat is studied. The objective is to place the peak boiler in a location where the overall costs are the smallest. Following this rule, the results indicate that the peak boiler should be located at the CHP plant if that allows using cheaper ‘self-use electricity’ in CHP for distributing the heat. However, if the market electricity price is used everywhere, or if energy efficiency is more emphasized, the location of the peak boiler should be closer to the users with dense heat loads. - Highlights: • Location for peak heating in the CHP based combined DH system is studied. • Regulation or control strategies for combined DH are summarized. • The heat load duration curve for combined DH is demonstrated. • Network design for combined DH with peak boiler outside of the CHP is analyzed

  5. Development of a Packaged and Integrated Microturbine/ Chiller Combined Heat and Power (CHP) System

    Energy Technology Data Exchange (ETDEWEB)

    None

    2009-03-01

    This factsheet describes a research project whose goal is to define, develop, integrate, and validate at full scale the technology for a 1 MWe, microturbine-driven CHP packaged system for industrial or large commercial applications.

  6. Connection of small RES and CHP power generation units to the electricity systems

    International Nuclear Information System (INIS)

    The EU member states have to ensure to the producers of 'green' electricity guaranteed access to the electrical grid including for small installations - Directive (2001/77/EC) of EC. For this reason the European Commission (EC) supports the project 'Production of Electricity with RES and CHP for Homeowners' - PERCH, in the framework of the program 'Intelligent Energy - Europe'. In the report the issues of connection (technical, contractual, tariff and metering) are investigated for small installations using RES and micro CHP, which are owned by individual family houses, small enterprises, etc. It is pointed out that small installations, mainly PV-systems, wind generators and small CHP, as well as combination of these technologies are rapidly applied on the European market. In Bulgaria the application of small PV-systems and wind generators, as well as CHP at present is limited. The elements for encouragement of such systems are defined, as well as the barriers for their wider application. (author)

  7. Optimal design of integrated CHP systems for housing complexes

    International Nuclear Information System (INIS)

    Highlights: • An optimization formulation for designing domestic CHP systems is presented. • The operating scheme, prime mover and thermal storage system are optimized. • Weather conditions and behavior demands are considered. • Simultaneously economic and environmental objectives are considered. • Two case studies from Mexico are presented. - Abstract: This paper presents a multi-objective optimization approach for designing residential cogeneration systems based on a new superstructure that allows satisfying the demands of hot water and electricity at the minimum cost and the minimum environmental impact. The optimization involves the selection of technologies, size of required units and operating modes of equipment. Two residential complexes in different cities of the State of Michoacán in Mexico were considered as case studies. One is located on the west coast and the other one is in the mountainous area. The results show that the implementation of the proposed optimization method yields significant economic and environmental benefits due to the simultaneous reduction in the total annual cost and overall greenhouse gas emissions

  8. The CckA-ChpT-CtrA phosphorelay system is regulated by quorum sensing and controls flagellar motility in the marine sponge symbiont Ruegeria sp. KLH11.

    Directory of Open Access Journals (Sweden)

    Jindong Zan

    Full Text Available Bacteria respond to their environment via signal transduction pathways, often two-component type systems that function through phosphotransfer to control expression of specific genes. Phosphorelays are derived from two-component systems but are comprised of additional components. The essential cckA-chpT-ctrA phosphorelay in Caulobacter crescentus has been well studied and is important in orchestrating the cell cycle, polar development and flagellar biogenesis. Although cckA, chpT and ctrA homologues are widespread among the Alphaproteobacteria, relatively few is known about their function in the large and ecologically significant Roseobacter clade of the Rhodobacterales. In this study the cckA-chpT-ctrA system of the marine sponge symbiont Ruegeria sp. KLH11 was investigated. Our results reveal that the cckA, chpT and ctrA genes positively control flagellar biosynthesis. In contrast to C. crescentus, the cckA, chpT and ctrA genes in Ruegeria sp. KLH11 are non-essential and do not affect bacterial growth. Gene fusion and transcript analyses provide evidence for ctrA autoregulation and the control of motility-related genes. In KLH11, flagellar motility is controlled by the SsaRI system and acylhomoserine lactone (AHL quorum sensing. SsaR and long chain AHLs are required for cckA, chpT and ctrA gene expression, providing a regulatory link between flagellar locomotion and population density in KLH11.

  9. Analysis of the impact of Heat-to-Power Ratio for a SOFC-based mCHP system for residential application under different climate regions in Europe

    DEFF Research Database (Denmark)

    Liso, Vincenzo; Zhao, Yingru; Brandon, Nigel;

    2011-01-01

    In this paper, the ability of a micro combined heat and power (mCHP) system to cover the heat and electricity demand of a single-family residence is investigated. A solid oxide fuel cell based mCHP system coupled with a hot water storage tank is analyzed. The energy profiles of single-family hous...... and hot water are still in demand. This maximises the running time of the fuel cell, and thus the economic and environmental benefit of the system, without wasting produced heat.......In this paper, the ability of a micro combined heat and power (mCHP) system to cover the heat and electricity demand of a single-family residence is investigated. A solid oxide fuel cell based mCHP system coupled with a hot water storage tank is analyzed. The energy profiles of single......-family households in different European countries are evaluated. The range of Heat-to-Power Ratio for the SOFC based mCHP System of 0.5 to 1.5 shows good agreement with the hot water, space heating and electricity demand during the warm seasons across Europe. This suggests that the fuel cell system should be sized...

  10. Fuel cell power plants for decentralised CHP applications; Brennstoffzellen-Kraftwerke fuer dezentrale KWK-Anwendungen

    Energy Technology Data Exchange (ETDEWEB)

    Ohmer, Martin; Mattner, Katja [FuelCell Energy Solutions GmbH, Dresden (Germany)

    2015-06-01

    Fuel cells are the most efficient technology to convert chemical energy into electricity and heat and thus they could have a major impact on reducing fuel consumption, CO{sub 2} and other emissions (NO{sub x}, SO{sub x} and particulate matter). Fired with natural or biogas and operated with an efficiency of up to 49 % a significant reduction of fuel costs can be achieved in decentralised applications. Combined heat and power (CHP) configurations add value for a wide range of industrial applications. The exhaust heat of approximately 400 C can be utilised for heating purposes and the production of steam. Besides, it can be also fed directly to adsorption cooling systems. With more than 110 fuel cell power plants operating worldwide, this technology is a serious alternative to conventional gas turbines or gas engines.

  11. Regulatory Compliance and Environmental Benefit Analysis of Combined Heat and Power (CHP Systems in Taiwan

    Directory of Open Access Journals (Sweden)

    Wen-Tien Tsai

    2013-01-01

    Full Text Available The energy conservation achieved by utilizing waste heat in the energy and industrial sectors has became more and more important after the energy crisis in the 1970s because it plays a vital role in the potential energy-efficiency improvement. In this regard, cogeneration (combined heat and power, CHP systems are thus becoming attractive due to the energy, economic, and environmental policies for pursuing stable electricity supply, sustainable development and environmental pollution mitigation in Taiwan. The objective of this paper is to present an updated analysis of CHP systems in Taiwan during the period from 1990 to 2010. The description in the paper is thus based on an analysis of electricity supply/consumption and its sources from CHP systems during the past two decades, and centered on two important regulations in compliance with CHP systems (i.e., Energy Management Law and Environmental Impact Assessment Act. Based on the total net power generation from CHP systems (i.e., 35,626 GWh in 2011, it was found that the carbon dioxide reduction benefits were estimated to be around 20,000 Gg.

  12. Ecological assessment of new CHP systems and their combination; Oekologische Bewertung neuer WKK-Systeme und Systemkombinationen - Schlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Primas, A.

    2007-07-01

    This final report for the Swiss Federal Office of Energy (SFOE) reports on new developments in the Combined Heat and Power (CHP) generation area. The objective of this study is an ecological and technical evaluation of various CHP systems and system combinations. These also include suitable combinations with other technologies. Systems for five different temperature levels are quantified according to their environmental impact. Various possible applications are compared with a highly efficient reference system using separate heat and power generation - a combined-cycle plant and a heat pump. For chilled water production a combination of the CHP system with an absorption chiller is investigated. The results of the investigations are presented and commented on. Also, advantageous applications of CHP systems are noted.

  13. Development of a micro-cogeneration laboratory and testing of a natural gas CHP unit based on PEM fuel cells

    International Nuclear Information System (INIS)

    This work discusses the design and the development of a Laboratory of Micro-Cogeneration (LMC) at Politecnico di Milano. The LMC laboratory is a unique structure devoted to small-scale power generation, with the main goals of testing and improving the performance of systems that produce or utilize electric and thermal (hot and/or cold) power in a very general sense, spanning from combined heat and power (CHP) units to heaters, from absorption chillers to heat pumps, but also able to perform tests on fuel processors and electrolyzers. The laboratory features a supply of natural gas as well as H2 and O2 from a high pressure electrolyzer and of CO, CO2 and N2 from bottles, permitting to carry out experiments with simulated synthesis fuels. The maximum allowable electrical power produced, exported to the grid or to an electronic loadbank, or consumed by the system under test is 100 kW; maximum allowable thermal power is roughly 200 kW with variable temperature water circuits (from chilled water up to a 150 °C at 8 bar superheated water loop). This work outlines also the instruments used for on-line recording of thermodynamic properties, emissions and power, aiming at monitoring and reconstructing mass and energy balances. One of the first experimental campaign has been carried out on a CHP system based on polymer electrolyte membrane fuel cells (PEM), a promising candidate for distributed CHP thanks to low pollutant emissions and good efficiency, rapid startup and flexibility, although affected by a rather complex fuel processing section to provide the appropriate fuel to the PEM. This work presents the experimental analysis of a 20 kW prototype PEM CHP system complete of natural gas processor. The prototype is operated at LMC to characterize the processing section and the thermodynamic performances of the overall system. Despite its non-optimized layout, the unit has shown encouraging total efficiency (76%) and primary energy saving index (6%). - Highlights:

  14. Optimal design and operation of a syngas-fuelled SOFC micro CHP system for residential applications in different climate zones in China

    OpenAIRE

    Yang, Wenyuan; Zhao, Yingru; Liso, Vincenzo; BRANDON, Nigel

    2014-01-01

    Fuel cell based micro-CHP systems are expected to be one of the most promising technologies for implementation in the residential sector. Since the design and operation of such CHP systems are greatly dependent upon the seasonal atmospheric conditions, it is important to evaluate their performance under difference climate conditions to ensure that it is well matched with the local heat-to-power ratio. The aim of this study is to investigate the optimal design and operation of a syngas-fuelled...

  15. Structural insights into ChpT, an essential dimeric histidine phosphotransferase regulating the cell cycle in Caulobacter crescentus

    OpenAIRE

    Fioravanti, Antonella; Clantin, Bernard; Dewitte, Frédérique; Lens, Zoé; Verger, Alexis; Biondi, Emanuele G; Villeret, Vincent

    2012-01-01

    Two-component and phosphorelay signal-transduction proteins are crucial for bacterial cell-cycle regulation in Caulobacter crescentus. ChpT is an essential histidine phosphotransferase that controls the activity of the master cell-cycle regulator CtrA by phosphorylation. Here, the 2.2 Å resolution crystal structure of ChpT is reported. ChpT is a homodimer and adopts the domain architecture of the intracellular part of class I histidine kinases. Each subunit consists of two distinct domains: a...

  16. Modeling and parametric study of a 1 kWe HT-PEMFC-based residential micro-CHP system

    DEFF Research Database (Denmark)

    Arsalis, Alexandros; Nielsen, Mads Pagh; Kær, Søren Knudsen

    2011-01-01

    A detailed thermodynamic, kinetic and geometric model of a micro-CHP (Combined-Heatand-Power) residential system based on High Temperature-Proton Exchange Membrane Fuel Cell (HT-PEMFC) technology is developed, implemented and validated. HT-PEMFC technology is investigated as a possible candidate ...

  17. Structural insights into ChpT, an essential dimeric histidine phosphotransferase regulating the cell cycle in Caulobacter crescentus.

    Science.gov (United States)

    Fioravanti, Antonella; Clantin, Bernard; Dewitte, Frédérique; Lens, Zoé; Verger, Alexis; Biondi, Emanuele G; Villeret, Vincent

    2012-09-01

    Two-component and phosphorelay signal-transduction proteins are crucial for bacterial cell-cycle regulation in Caulobacter crescentus. ChpT is an essential histidine phosphotransferase that controls the activity of the master cell-cycle regulator CtrA by phosphorylation. Here, the 2.2 Å resolution crystal structure of ChpT is reported. ChpT is a homodimer and adopts the domain architecture of the intracellular part of class I histidine kinases. Each subunit consists of two distinct domains: an N-terminal helical hairpin domain and a C-terminal α/β domain. The two N-terminal domains are adjacent within the dimer, forming a four-helix bundle. The ChpT C-terminal domain adopts an atypical Bergerat ATP-binding fold.

  18. Evaluation of Combined Heat and Power (CHP Systems Using Fuzzy Shannon Entropy and Fuzzy TOPSIS

    Directory of Open Access Journals (Sweden)

    Fausto Cavallaro

    2016-06-01

    Full Text Available Combined heat and power (CHP or cogeneration can play a strategic role in addressing environmental issues and climate change. CHP systems require less fuel than separate heat and power systems in order to produce the same amount of energy saving primary energy, improving the security of the supply. Because less fuel is combusted, greenhouse gas emissions and other air pollutants are reduced. If we are to consider the CHP system as “sustainable”, we must include in its assessment not only energetic performance but also environmental and economic aspects, presenting a multicriteria issue. The purpose of the paper is to apply a fuzzy multicriteria methodology to the assessment of five CHP commercial technologies. Specifically, the combination of the fuzzy Shannon’s entropy and the fuzzy Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS approach will be tested for this purpose. Shannon’s entropy concept, using interval data such as the α-cut, is a particularly suitable technique for assigning weights to criteria—it does not require a decision-making (DM to assign a weight to the criteria. To rank the proposed alternatives, a fuzzy TOPSIS method has been applied. It is based on the principle that the chosen alternative should be as close as possible to the positive ideal solution and be as far as possible from the negative ideal solution. The proposed approach provides a useful technical–scientific decision-making tool that can effectively support, in a consistent and transparent way, the assessment of various CHP technologies from a sustainable point of view.

  19. Impact of carbon tax on internal combustion engine size selection in a medium scale CHP system

    International Nuclear Information System (INIS)

    Highlights: → We study sizing of internal combustion engines as the prime movers of a CHP system. → We study carbon tax impact on the economics of the system. → Diesel engine based systems is not economical regardless of the operational mode. → HDF is the only mode in which gas engine based systems is uneconomical. → Carbon price considerably affects the system payback period. -- Abstract: Combined heat and power (CHP) systems due to their high efficiency compared to the conventional power generation systems have received considerable attention as they have less harmful impact on the environment. Recently, the serious concern with reducing the greenhouse gas emissions has focussed the attention on the possibility of a carbon tax in some countries. Here, we address the impact of such tax on the sizing and economics of a CHP system. Optimum sizing of CHP systems is of great importance to maximize the benefits of these systems. To select the optimum prime mover of a CHP system, performance characteristics of engine as well as economic parameters should be taken into consideration. A general thermo-economic approach to optimum sizing of internal combustion engines as the prime movers (any type and size) of a medium scale CHP system (500-5000 kW) and planning their operational strategy is developed. Net Annual Cost (NAC) as the criterion for making decision is introduced and appropriate equations for estimating thermodynamic and economic parameters as well as greenhouse gas emissions are presented. We consider three modes of operation: one-way connection (OWC) mode, two-way connection (TWC) mode, and heat demand following (HDF) mode. The proposed method has been used for a case study where data is available in the literature and the optimum nominal powers using gas engines are 3.3 MW, 3.2 MW, and 1.2 MW and in the case of using diesel engines are 3.4 MW, 3.4 MW, and 1.4 MW for TWC, OWC, and HDF modes, respectively. To determine the sensitivity of results to

  20. A Simplified Nonlinear Model For A Combined Heat and Power (CHP) System

    OpenAIRE

    Karrari, M.; Nicholson, H

    1990-01-01

    Steady state errors, hunting and high interactions have been reported in the operation of combined heat and power (CHP) systems working with steam turbines. The design of currently employed regulators in industry is usually absed on a linear model of the system. An improved system regulation can only be achieved if a more accurate mathematical model is available. In this paper, a simplified nonlinear model is derived which can be used to investigate the present problems and evaluate new contr...

  1. Research, Development and Demonstration of Micro-CHP System for Residential Applications

    Energy Technology Data Exchange (ETDEWEB)

    Karl Mayer

    2010-03-31

    ECR International and its joint venture company, Climate Energy, are at the forefront of the effort to deliver residential-scale combined heat and power (Micro-CHP) products to the USA market. Part of this substantial program is focused on the development of a new class of steam expanders that offers the potential for significantly lower costs for small-scale power generation technology. The heart of this technology is the scroll expander, a machine that has revolutionized the HVAC refrigerant compressor industry in the last 15 years. The liquid injected cogeneration (LIC) technology is at the core of the efforts described in this report, and remains an excellent option for low cost Micro-CHP systems. ECR has demonstrated in several prototype appliances that the concept for LIC can be made into a practical product. The continuing challenge is to identify economical scroll machine designs that will meet the performance and endurance requirements needed for a long life appliance application. This report describes the numerous advances made in this endeavor by ECR International. Several important advances are described in this report. Section 4 describes a marketing and economics study that integrates the technical performance of the LIC system with real-world climatic data and economic analysis to assess the practical impact that different factors have on the economic application of Micro-CHP in residential applications. Advances in the development of a working scroll steam expander are discussed in Section 5. A rigorous analytical assessment of the performance of scroll expanders, including the difficult to characterize impact of pocket to pocket flank leakage, is presented in Section 5.1. This is followed with an FEA study of the thermal and pressure induced deflections that would result from the normal operation of an advanced scroll expander. Section 6 describes the different scroll expanders and test fixtures developed during this effort. Another key technical

  2. Genetic Analysis of the Regulation of Type IV Pilus Function by the Chp Chemosensory System of Pseudomonas aeruginosa▿

    OpenAIRE

    Bertrand, Jacob J.; West, Joyce T.; Engel, Joanne N.

    2009-01-01

    The virulence of the opportunistic pathogen Pseudomonas aeruginosa involves the coordinate expression of many virulence factors, including type IV pili, which are required for colonization of host tissues and for twitching motility. Type IV pilus function is controlled in part by the Chp chemosensory system, which includes a histidine kinase, ChpA, and two CheY-like response regulators, PilG and PilH. How the Chp components interface with the type IV pilus motor proteins PilB, PilT, and PilU ...

  3. Modelling of energy systems with a high percentage of CHP and wind power

    Energy Technology Data Exchange (ETDEWEB)

    Lund, H. [Aalborg University (Denmark). Dept. of Development and Planning; Muenster, E. [PlanEnergi s/i, Skorping (Denmark)

    2003-11-01

    This paper presents the energy system analysis model EnergyPLAN, which has been used to analyse the integration of large scale wind power into the national Danish electricity system. The main purpose of the EnergyPLAN model is to design suitable national energy planning strategies by analysing the consequences of different national energy investments. The model emphasises the analysis of different regulation strategies and different market economic optimisation strategies. At present wind power supply 15% of the Danish electricity demand and ca 50% is produced in CHP (combined heat and power production). The model has been used in the work of an expert group conducted by the Danish Energy Agency for the Danish Parliament. Results are included in the paper in terms of strategies, in order to manage the integration of CHP and wind power in the future Danish energy supply in which more than 40% of the supply is expected to come from wind power. (author)

  4. Modeling of non-linear CHP efficiency curves in distributed energy systems

    DEFF Research Database (Denmark)

    Milan, Christian; Stadler, Michael; Cardoso, Gonçalo;

    2015-01-01

    Distributed energy resources gain an increased importance in commercial and industrial building design. Combined heat and power (CHP) units are considered as one of the key technologies for cost and emission reduction in buildings. In order to make optimal decisions on investment and operation...... for these technologies, detailed system models are needed. These models are often formulated as linear programming problems to keep computational costs and complexity in a reasonable range. However, CHP systems involve variations of the efficiency for large nameplate capacity ranges and in case of part load operation......, which can be even of non-linear nature. Since considering these characteristics would turn the models into non-linear problems, in most cases only constant efficiencies are assumed. This paper proposes possible solutions to address this issue. For a mixed integer linear programming problem two...

  5. Regulatory Compliance and Environmental Benefit Analysis of Combined Heat and Power (CHP) Systems in Taiwan

    OpenAIRE

    Wen-Tien Tsai

    2013-01-01

    The energy conservation achieved by utilizing waste heat in the energy and industrial sectors has became more and more important after the energy crisis in the 1970s because it plays a vital role in the potential energy-efficiency improvement. In this regard, cogeneration (combined heat and power, CHP) systems are thus becoming attractive due to the energy, economic, and environmental policies for pursuing stable electricity supply, sustainable development and environmental pollution mitigati...

  6. A Comparative Technological Review of Hybrid CSP-Biomass CHP Systems in Europe

    OpenAIRE

    Hussain, C. M. Iftekhar; Duffy, Aidan; Norton, Brian

    2015-01-01

    This paper aims to explore different solar technologies and its suitability for hybridization with biomass for combined heat and power (CHP) generation in Europe. Although hybrid solar-biomass research and demonstration is in its infancy, it has the potential to provide dispatchable renewable energy at a significant scale over many areas in Europe. Therefore, this review examines the technical and economic reported performances on hybrid systems in order to assess the technical and economic v...

  7. DEVELOPMENT OF THE CHP-THERMAL SCHEMES IN CONTEXTS OF THE CONSOLIDATED ENERGY SYSTEM OF BELARUS

    OpenAIRE

    V. N. Romaniuk; A. A. Bobich

    2015-01-01

    The paper deals with the structural specifics of the Belarus Consolidated Energy System capacities in view of their ongoing transfer to the combined-cycle technology, building the nuclear power plant and necessity for the generating capacity regulation in compliance with the load diagram. With the country’s economic complex energy utilization pattern being preserved, the generating capacities are subject to restructuring and the CHP characteristics undergo enhancement inter alia a well-known ...

  8. Environmental sustainability analysis of UK whole-wheat bioethanol and CHP systems

    International Nuclear Information System (INIS)

    The UK whole-wheat bioethanol and straw and DDGS-based combined heat and power (CHP) generation systems were assessed for environmental sustainability using a range of impact categories or characterisations (IC): cumulative primary fossil energy (CPE), land use, life cycle global warming potential over 100 years (GWP100), acidification potential (AP), eutrophication potential (EP) and abiotic resources use (ARU). The European Union (EU) Renewable Energy Directive's target of greenhouse gas (GHG) emission saving of 60% in comparison to an equivalent fossil-based system by 2020 seems to be very challenging for stand-alone wheat bioethanol system. However, the whole-wheat integrated system, wherein the CHP from the excess straw grown in the same season and from the same land is utilised in the wheat bioethanol plant, can be demonstrated for potential sustainability improvement, achieving 85% emission reduction and 97% CPE saving compared to reference fossil systems. The net bioenergy from this system and from 172,370 ha of grade 3 land is 12.1 PJ y−1 providing land to energy yield of 70 GJ ha−1 y−1. The use of DDGS as an animal feed replacing soy meal incurs environmental emission credit, whilst its use in heat or CHP generation saves CPE. The hot spots in whole system identified under each impact category are as follows: bioethanol plant and wheat cultivation for CPE (50% and 48%), as well as for ARU (46% and 52%). EP and GWP100 are distributed among wheat cultivation (49% and 37%), CHP plant (26% and 30%) and bioethanol plant (25%, and 33%), respectively. -- Highlights: ► UK whole-wheat energy system can achieve 85% GHG emission reduction. ► UK whole-wheat energy system can achieve 97% primary energy saving. ► The land to energy yield of the UK whole-wheat system is 70 GJ ha−1 y−1. ► Fertiliser production is the hotspot. ► DDGS and straw-based CHP system integration to wheat bioethanol is feasible

  9. A Study of a Diesel Engine Based Micro-CHP System

    Energy Technology Data Exchange (ETDEWEB)

    Krishna, C.R.; Andrews, J.; Tutu, N.; Butcher, T.

    2010-08-31

    This project, funded by New York State Energy Research and Development Agency (NYSERDA), investigated the potential for an oil-fired combined heat and power system (micro-CHP system) for potential use in residences that use oil to heat their homes. Obviously, this requires the power source to be one that uses heating oil (diesel). The work consisted of an experimental study using a diesel engine and an analytical study that examined potential energy savings and benefits of micro-CHP systems for 'typical' locations in New York State. A search for a small diesel engine disclosed that no such engines were manufactured in the U.S. A single cylinder engine manufactured in Germany driving an electric generator was purchased for the experimental work. The engine was tested using on-road diesel fuel (15 ppm sulfur), and biodiesel blends. One of the main objectives was to demonstrate the possibility of operation in the so-called HCCI (Homogeneous Charge Compression Ignition) mode. The HCCI mode of operation of engines is being explored as a way to reduce the emission of smoke, and NOx significantly without exhaust treatment. This is being done primarily in the context of engines used in transportation applications. However, it is felt that in a micro-CHP application using a single cylinder engine, such an approach would confer those emission benefits and would be much easier to implement. This was demonstrated successfully by injecting the fuel into the engine air intake using a heated atomizer made by Econox Technologies LLC to promote significant vaporization before entering the cylinder. Efficiency and emission measurements were made under different electrical loads provided by two space heaters connected to the generator in normal and HCCI modes of operation. The goals of the analytical work were to characterize, from the published literature, the prime-movers for micro-CHP applications, quantify parametrically the expected energy savings of using micro-CHP

  10. Evaluation of the operational cost savings potential from a D-CHP system based on a monthly power-to-heat ratio analysis

    OpenAIRE

    Alta Knizley; Pedro J. Mago; James Tobermann

    2015-01-01

    This paper focuses on the analysis of a combined heat and power (CHP) system utilizing two power generation units operating simultaneously under differing operational strategies (D-CHP) on the basis of operational cost savings. A cost optimization metric, based on the facility monthly power-to-heat ratio (PHR), is presented in this paper. The PHR is defined as the ratio between the facility electric load and thermal load. Previous work in this field has suggested that D-CHP system performance...

  11. Trial operation of a phosphoric acid fuel cell (PC25) for CHP applications in Europe

    Energy Technology Data Exchange (ETDEWEB)

    Uhrig, M.; Droste, W.; Wolf, D. [Ruhrgas AG, Dorsten (Germany)

    1996-12-31

    In Europe, ten 200 kW phosphoric acid fuel cells (PAFCs) produced by ONSI (PC25) are currently in operation. Their operators collaborate closely in the European Fuel Cell Users Group (EFCUG). The experience gained from trial operation by the four German operators - HEAG, HGW/HEW, Thyssengas and Ruhrgas - coincides with that of the other European operators. This experience can generally be regarded as favourable. With a view to using fuel cells in combined heat and power generation (CHP), the project described in this report, which was carried out in cooperation with the municipal utility of Bochum and Gasunie of the Netherlands, aimed at gaining experience with the PC 25 in field operation under the specific operating conditions prevailing in Europe. The work packages included heat-controlled operation, examination of plant behavior with varying gas properties and measurement of emissions under dynamic load conditions. The project received EU funding under the JOULE programme.

  12. DEVELOPMENT OF THE CHP-THERMAL SCHEMES IN CONTEXTS OF THE CONSOLIDATED ENERGY SYSTEM OF BELARUS

    Directory of Open Access Journals (Sweden)

    V. N. Romaniuk

    2015-01-01

    Full Text Available The paper deals with the structural specifics of the Belarus Consolidated Energy System capacities in view of their ongoing transfer to the combined-cycle technology, building the nuclear power plant and necessity for the generating capacity regulation in compliance with the load diagram. With the country’s economic complex energy utilization pattern being preserved, the generating capacities are subject to restructuring and the CHP characteristics undergo enhancement inter alia a well-known increase of the specific electricity production based on the heat consumption. Because of this the steam-turbine condensation units which are the traditional capacity regulators for the energy systems with heat power plants dominance are being pushed out of operation. In consequence of this complex of changes the issue of load diagram provision gains momentum which in evidence is relevant to the Consolidated Energy System of Belarus. One of the ways to alleviate acuteness of the problem could be the specific electric energy production cut on the CHP heat consumption with preserving the heat loads and without their handover to the heat generating capacities of direct combustion i.e. without fuel over-burning. The solution lies in integrating the absorption bromous-lithium heat pump units into the CHP thermal scheme. Through their agency low-temperature heat streams of the generator cooling, the lubrication and condensation heat-extraction of steam minimal passing to the condenser systems are utilized. As a case study the authors choose one of the CHPs in the conditions of which the corresponding employment of the said pumps leads to diminution of the fuel-equivalent specific flow-rate by 20−25 g for 1 kW⋅h production and conjoined electric energy generation capacity lowering. The latter will be handed over to other generating capacities, and the choice of them affects economic expediency of the absorption bromous-lithium heat pump-units installation

  13. A Study of a Diesel Engine Based Micro-CHP System

    Energy Technology Data Exchange (ETDEWEB)

    Krishna, C.R.; Andrews, J.; Tutu, N.; Butcher, T.

    2010-08-31

    This project, funded by New York State Energy Research and Development Agency (NYSERDA), investigated the potential for an oil-fired combined heat and power system (micro-CHP system) for potential use in residences that use oil to heat their homes. Obviously, this requires the power source to be one that uses heating oil (diesel). The work consisted of an experimental study using a diesel engine and an analytical study that examined potential energy savings and benefits of micro-CHP systems for 'typical' locations in New York State. A search for a small diesel engine disclosed that no such engines were manufactured in the U.S. A single cylinder engine manufactured in Germany driving an electric generator was purchased for the experimental work. The engine was tested using on-road diesel fuel (15 ppm sulfur), and biodiesel blends. One of the main objectives was to demonstrate the possibility of operation in the so-called HCCI (Homogeneous Charge Compression Ignition) mode. The HCCI mode of operation of engines is being explored as a way to reduce the emission of smoke, and NOx significantly without exhaust treatment. This is being done primarily in the context of engines used in transportation applications. However, it is felt that in a micro-CHP application using a single cylinder engine, such an approach would confer those emission benefits and would be much easier to implement. This was demonstrated successfully by injecting the fuel into the engine air intake using a heated atomizer made by Econox Technologies LLC to promote significant vaporization before entering the cylinder. Efficiency and emission measurements were made under different electrical loads provided by two space heaters connected to the generator in normal and HCCI modes of operation. The goals of the analytical work were to characterize, from the published literature, the prime-movers for micro-CHP applications, quantify parametrically the expected energy savings of using micro-CHP

  14. WORKING PARK-FUEL CELL COMBINED HEAT AND POWER SYSTEM

    Energy Technology Data Exchange (ETDEWEB)

    Allan Jones

    2003-09-01

    This report covers the aims and objectives of the project which was to design, install and operate a fuel cell combined heat and power (CHP) system in Woking Park, the first fuel cell CHP system in the United Kingdom. The report also covers the benefits that were expected to accrue from the work in an understanding of the full technology procurement process (including planning, design, installation, operation and maintenance), the economic and environmental performance in comparison with both conventional UK fuel supply and conventional CHP and the commercial viability of fuel cell CHP energy supply in the new deregulated energy markets.

  15. District Heating System Using Heat Pump Installations and CHP

    Directory of Open Access Journals (Sweden)

    Sit M.L.

    2015-12-01

    Full Text Available The article describes the district heating system, in which part of the heat of return water thermal power is used to supply heat to the district heating puThe article describes the district heating system, in which part of the heat of return water thermal power is used to supply heat to the district heating pumps, evaporators heating and hot water. Heat pumps use carbon dioxide as refrigerant. During the transitional period of the year, and the summer heat pump for preparing hot-water supply system uses the heat of the surrounding air. The heat of the ambient air is used in the intermediate heat exchanger between the first and second stages of the heat pump to cool the gas after the first stage of the compressor of the heat pump.

  16. Thermal gain of CHP steam generator plants and heat supply systems

    Science.gov (United States)

    Ziganshina, S. K.; Kudinov, A. A.

    2016-08-01

    Heating calculation of the surface condensate heat recovery unit (HRU) installed behind the BKZ-420-140 NGM boiler resulting in determination of HRU heat output according to fire gas value parameters at the heat recovery unit inlet and its outlet, heated water quantity, combustion efficiency per boiler as a result of installation of HRU, and steam condensate discharge from combustion products at its cooling below condensing point and HRU heat exchange area has been performed. Inspection results of Samara CHP BKZ-420-140 NGM power boilers and field tests of the surface condensate heat recovery unit (HRU) made on the bimetal calorifier base KCk-4-11 (KSk-4-11) installed behind station no. 2 Ulyanovsk CHP-3 DE-10-14 GM boiler were the basis of calculation. Integration of the surface condensation heat recovery unit behind a steam boiler rendered it possible to increase combustion efficiency and simultaneously decrease nitrogen oxide content in exit gases. Influence of the blowing air moisture content, the excess-air coefficient in exit gases, and exit gases temperature at the HRU outlet on steam condensate amount discharge from combustion products at its cooling below condensing point has been analyzed. The steam condensate from HRU gases is offered as heat system make-up water after degasification. The cost-effectiveness analysis of HRU installation behind the Samara CHP BKZ-420-140 NGM steam boiler with consideration of heat energy and chemically purified water economy has been performed. Calculation data for boilers with different heat output has been generalized.

  17. Thermal gain of CHP steam generator plants and heat supply systems

    Science.gov (United States)

    Ziganshina, S. K.; Kudinov, A. A.

    2016-08-01

    Heating calculation of the surface condensate heat recovery unit (HRU) installed behind the BKZ-420-140 NGM boiler resulting in determination of HRU heat output according to fire gas value parameters at the heat recovery unit inlet and its outlet, heated water quantity, combustion efficiency per boiler as a result of installation of HRU, and steam condensate discharge from combustion products at its cooling below condensing point and HRU heat exchange area has been performed. Inspection results of Samara CHP BKZ-420-140 NGM power boilers and field tests of the surface condensate heat recovery unit (HRU) made on the bimetal calorifier base КСк-4-11 (KSk-4-11) installed behind station no. 2 Ulyanovsk CHP-3 DE-10-14 GM boiler were the basis of calculation. Integration of the surface condensation heat recovery unit behind a steam boiler rendered it possible to increase combustion efficiency and simultaneously decrease nitrogen oxide content in exit gases. Influence of the blowing air moisture content, the excess-air coefficient in exit gases, and exit gases temperature at the HRU outlet on steam condensate amount discharge from combustion products at its cooling below condensing point has been analyzed. The steam condensate from HRU gases is offered as heat system make-up water after degasification. The cost-effectiveness analysis of HRU installation behind the Samara CHP BKZ-420-140 NGM steam boiler with consideration of heat energy and chemically purified water economy has been performed. Calculation data for boilers with different heat output has been generalized.

  18. Energy efficiency analysis and impact evaluation of the application of thermoelectric power cycle to today's CHP systems

    DEFF Research Database (Denmark)

    Chen, Min; Lund, Henrik; Rosendahl, Lasse;

    2010-01-01

    configurations for combustion systems. The feasible deployment of TEG in various CHP plants will be examined in terms of heat source temperature range, influences on CHP power specification and thermal environment, as well as potential benefits. The overall conversion efficiency improvements and economic......High efficiency thermoelectric generators (TEG) can recover waste heat from both industrial and private sectors. Thus, the development and deployment of TEG may represent one of the main drives for technological change and fuel substitution. This paper will present an analysis of system efficiency...

  19. Research, Development and Demonstration of Micro-CHP Systems for Residential Applications - Phase I

    Energy Technology Data Exchange (ETDEWEB)

    Robert A. Zogg

    2011-03-14

    The objective of the Micro-CHP Phase I effort was to develop a conceptual design for a Micro-CHP system including: Defining market potential; Assessing proposed technology; Developing a proof-of-principle design; and Developing a commercialization strategy. TIAX LLC assembled a team to develop a Micro-CHP system that will provide electricity and heating. TIAX, the contractor and major cost-share provider, provided proven expertise in project management, prime-mover design and development, appliance development and commercialization, analysis of residential energy loads, technology assessment, and market analysis. Kohler Company, the manufacturing partner, is a highly regarded manufacturer of standby power systems and other residential products. Kohler provides a compellingly strong brand, along with the capabilities in product development, design, manufacture, distribution, sales, support, service, and marketing that only a manufacturer of Kohler's status can provide. GAMA, an association of appliance and equipment manufacturers, provided a critical understanding of appliance commercialization issues, including regulatory requirements, large-scale market acceptance issues, and commercialization strategies. The Propane Education & Research Council, a cost-share partner, provided cost share and aided in ensuring the fuel flexibility of the conceptual design. Micro-CHP systems being commercialized in Europe and Japan are generally designed to follow the household thermal load, and generate electricity opportunistically. In many cases, any excess electricity can be sold back to the grid (net metering). These products, however, are unlikely to meet the demands of the U.S. market. First, these products generally cannot provide emergency power when grid power is lost--a critical feature to market success in the U.S. Even those that can may have insufficient electric generation capacities to meet emergency needs for many U.S. homes. Second, the extent to which net

  20. Optimal Design and Operation of A Syngas-fuelled SOFC Micro-CHP System for Residential Applications in Different Climate Zones in China

    DEFF Research Database (Denmark)

    Yang, Wenyuan; Liso, Vincenzo; Zhao, Yingru

    2013-01-01

    and operation of CHP system are greatly dependent upon the seasonal atmospheric conditions, which determine directly the thermal and electrical demands of residents, it is important to evaluate the performance of the CHP system under difference climate conditions to ensure that it matches well with the local...... heat-to-power load ratio. Therefore, the aim of this study is to investigate the optimal design and operation of a syngas-fuelled SOFC micro-CHP system for small households located in five different climate zones in China. The ability of the micro-CHP to cover the heat and electricity demand of a 70m2...... for sizing the system components of the micro-CHP are addressed specifically. The developed methodology can be applied to different types of residence with different load profiles....

  1. Economic potentials of CHP connected to district heat systems in Germany. Implementation of the EU Efficiency Directive

    International Nuclear Information System (INIS)

    The EU Efficiency Directive (2012/27/EU) is requiring all member states to carry out an evaluation of the potential for highly efficient CHP and the efficient use of district heating and cooling by December 2015. The German Federal Ministry of Economic Affairs and Energy appointed this task to the Fraunhofer Institute for Manufacturing and Advanced Materials, division for Energy Systems Analysis (formerly Bremer Energie Institut) in conjunction with other partners. The results for the sector district- and communal heating with CHP, sub-sectors private households, trade and services industry, are presented in this article.

  2. Energy efficiency analysis and impact evaluation of the application of thermoelectric power cycle to today's CHP systems

    International Nuclear Information System (INIS)

    High efficiency thermoelectric generators (TEG) can recover waste heat from both industrial and private sectors. Thus, the development and deployment of TEG may represent one of the main drives for technological change and fuel substitution. This paper will present an analysis of system efficiency related to the integration of TEG into thermal energy systems, especially Combined Heat and Power production (CHP). Representative implementations of installing TEG in CHP plants to utilize waste heat, wherein electricity can be generated in situ as a by-product, will be described to show advantageous configurations for combustion systems. The feasible deployment of TEG in various CHP plants will be examined in terms of heat source temperature range, influences on CHP power specification and thermal environment, as well as potential benefits. The overall conversion efficiency improvements and economic benefits, together with the environmental impact of this deployment, will then be estimated. By using the Danish thermal energy system as a paradigm, this paper will consider the TEG application to district heating systems and power plants through the EnergyPLAN model, which has been created to design suitable energy strategies for the integration of electricity production into the overall energy system.

  3. Australian coal mine methane emissions mitigation potential using a Stirling engine-based CHP system

    International Nuclear Information System (INIS)

    Methane, a major contributor to global warming, is a greenhouse gas emitted from coal mines. Abundance of coal mines and consequently a considerable amount of methane emission requires drastic measures to mitigate harmful effects of coal mining on the environment. One of the commonly adopted methods is to use emitted methane to fuel power generation systems; however, instability of fuel sources hinders the development of systems using conventional prime movers. To address this, application of Stirling engines may be considered. Here, we develop a techno-economic methodology for conducting an optimisation-based feasibility study on the application of Stirling engines as the prime movers of coal mine CHP systems from an economic and an environmental point of view. To examine the impact of environmental policies on the economics of the system, the two commonly implemented ones (i.e. a carbon tax and emissions trading scheme) are considered. The methodology was applied to a local coal mine. The results indicate that incorporating the modelled system not only leads to a substantial reduction in greenhouse gas emissions, but also to improved economics. Further, due to the heavy economic burden, the carbon tax scheme creates great incentive for coal mine industry to address the methane emissions. -- Highlights: •We study the application of Stirling engines in coal mine CHP systems. •We develop a thermo-economic approach based on the net present worth analysis. •We examine the impact of a carbon tax and ETS on the economics of the system. •The modeled system leads to a substantial reduction in greenhouse gas emissions. •Carbon tax provides a greater incentive to address the methane emissions

  4. Experience of Implementing a Distributed Control System for Thermal and Mechanical and Electrical Equipment at the South-West CHP

    Energy Technology Data Exchange (ETDEWEB)

    Babkin, K. V., E-mail: babkin@uztec.ru; Tsvetkov, M. S.; Kostyuk, R. I.; Chugin, A. V. [SC “South-West CHP” (Russian Federation); Bilenko, V. A.; Molchanov, K. A.; Fedunov, V. V. [JSC “Interautomatika” (Russian Federation)

    2015-01-15

    Results of implementing an SPPA-T3000-based unified distributed control system for thermal and mechanical and electrical equipment at the South-West CHP are discussed. Hardware solutions for integration with local control systems, control of electrical equipment in compliance with the standards IEC 61850, Modbus RTU, and communication between the plant control system and the System Operator of the Unified Power System are described.

  5. Current status of fuel cell based combined heat and power systems for residential sector

    Science.gov (United States)

    Ellamla, Harikishan R.; Staffell, Iain; Bujlo, Piotr; Pollet, Bruno G.; Pasupathi, Sivakumar

    2015-10-01

    Combined Heat and Power (CHP) is the sequential or simultaneous generation of multiple forms of useful energy, usually electrical and thermal, in a single and integrated system. Implementing CHP systems in the current energy sector may solve energy shortages, climate change and energy conservation issues. This review paper is divided into six sections: the first part defines and classifies the types of fuel cell used in CHP systems; the second part discusses the current status of fuel cell CHP (FC-CHP) around the world and highlights the benefits and drawbacks of CHP systems; the third part focuses on techniques for modelling CHP systems. The fourth section gives a thorough comparison and discussion of the two main fuel cell technologies used in FC-CHP (PEMFC and SOFC), characterising their technical performance and recent developments from the major manufacturers. The fifth section describes all the main components of FC-CHP systems and explains the issues connected with their practical application. The last part summarises the above, and reflects on micro FC-CHP system technology and its future prospects.

  6. Elimination of restraints on the propagation of combined heat and power (CHP) generation systems in Switzerland

    International Nuclear Information System (INIS)

    This report for the Swiss Federal Office of Energy (SFOE) discusses the results of study initiated by the SFOE that was to investigate the reasons for the low level of proliferation of CHP technology in Switzerland. The two main questions asked - which factors inhibit the use of CHP in particular application areas and which energy-policy measures can remove such obstacles - are discussed. The use of CHP in various areas of application from waste incineration plants through to units used in residential buildings is analysed and commented on. Recommendations on measures that can be taken to enhance the use of CHP are discussed. Three strategy variants available to the public services area are presented and discussed. It is noted that a consensus between players in the technical and political areas is necessary

  7. Desiccant HVAC system driven by a micro-CHP: Experimental analysis

    Energy Technology Data Exchange (ETDEWEB)

    Angrisani, Giovanni; Roselli, Carlo; Sasso, Maurizio [Universita degli Studi del Sannio, Dipartimento di Ingegneria, Piazza Roma 21, Benevento, 82100 (Italy); Minichiello, Francesco [Universita degli Studi di Napoli Federico II, DETEC, P.le Tecchio 80, Napoli, 80125 (Italy)

    2010-11-15

    In the Mediterranean area, there is increase in demand for summer cooling satisfied by electrically driven units in domestic and small commercial sectors; this involves electric peak loads and black-outs. Consequently, there is an increasing interest in small scale polygeneration systems fuelled by natural gas. In this paper, attention is paid to a test facility, located in Southern Italy, to carry out experimental analysis on a small scale polygeneration system based on a natural gas-fired Micro-CHP and a desiccant HVAC system. The MCHP provides thermal power, recovered from engine cooling and exhaust gas, for the regeneration of the desiccant wheel and electric power for the chiller, the auxiliaries and the external units (computers, lights, etc.). The HVAC system can also operate in traditional way, by interacting with electric grid and gas-fired boiler. An overview of the main experimental results is shown, considering both the desiccant wheel and the global polygeneration system. The experimental results confirm that the performances of the desiccant wheel are strongly influenced by outdoor thermal-hygrometric air properties and regeneration temperature. The polygeneration system guarantees primary energy savings up to 21.2% and greenhouse-gas emissions reductions up to 38.6% with respect to conventional HVAC systems based on separate energy ''production''. (author)

  8. Testing and model-aided analysis of a 2 kW el PEMFC CHP-system

    Science.gov (United States)

    König, P.; Weber, A.; Lewald, N.; Aicher, T.; Jörissen, L.; Ivers-Tiffée, E.; Szolak, R.; Brendel, M.; Kaczerowski, J.

    A prototype PEMFC CHP-system (combined heat and power) for decentralised energy supply in domestic applications has been installed in the Fuel Cell Testing Laboratory at the Institut für Werkstoffe der Elektrotechnik (IWE), Universität Karlsruhe (TH). The system, which was developed at the Zentrum für Sonnenenergie- und Wasserstoff-Forschung ZSW, Ulm (FC-stack) and the Fraunhofer-Institut für Solare Energiesysteme ISE, Freiburg (reformer) is operated and tested in close cooperation with the Stadtwerke Karlsruhe. The tests are carried out as part of the strategic project EDISon, which is supported by the German Federal Ministry of Economics and Technology (BMWA). The performance of the system is evaluated for different operating conditions. The tests include steady state measurements under different electrical and thermal loads as well as an analysis of the dynamic behaviour of the system during load changes. First results of these steady state and dynamic operation characteristics will be presented in this paper.

  9. Examination of energy price policies in Iran for optimal configuration of CHP and CCHP systems based on particle swarm optimization algorithm

    International Nuclear Information System (INIS)

    The current subsidized energy prices in Iran are proposed to be gradually eliminated over the next few years. The objective of this study is to examine the effects of current and future energy price policies on optimal configuration of combined heat and power (CHP) and combined cooling, heating, and power (CCHP) systems in Iran, under the conditions of selling and not-selling electricity to utility. The particle swarm optimization algorithm is used for minimizing the cost function for owning and operating various CHP and CCHP systems in an industrial dairy unit. The results show that with the estimated future unsubsidized utility prices, CHP and CCHP systems operating with reciprocating engine prime mover have total costs of 5.6 and $2.9x106 over useful life of 20 years, respectively, while both systems have the same capital recovery periods of 1.3 years. However, for the same prime mover and with current subsidized prices, CHP and CCHP systems require 4.9 and 5.2 years for capital recovery, respectively. It is concluded that the current energy price policies hinder the promotion of installing CHP and CCHP systems and, the policy of selling electricity to utility as well as eliminating subsidies are prerequisites to successful widespread utilization of such systems.

  10. Examination of energy price policies in Iran for optimal configuration of CHP and CCHP systems based on particle swarm optimization algorithm

    Energy Technology Data Exchange (ETDEWEB)

    Tichi, S.G.; Ardehali, M.M.; Nazari, M.E. [Energy Research Center, Department of Electrical Engineering, Amirkabir University of Technology (Tehran Polytechnic), 424 Hafez Ave., Tehran 15825-4413 (Iran)

    2010-10-15

    The current subsidized energy prices in Iran are proposed to be gradually eliminated over the next few years. The objective of this study is to examine the effects of current and future energy price policies on optimal configuration of combined heat and power (CHP) and combined cooling, heating, and power (CCHP) systems in Iran, under the conditions of selling and not-selling electricity to utility. The particle swarm optimization algorithm is used for minimizing the cost function for owning and operating various CHP and CCHP systems in an industrial dairy unit. The results show that with the estimated future unsubsidized utility prices, CHP and CCHP systems operating with reciprocating engine prime mover have total costs of 5.6 and 2.9 x 10{sup 6} over useful life of 20 years, respectively, while both systems have the same capital recovery periods of 1.3 years. However, for the same prime mover and with current subsidized prices, CHP and CCHP systems require 4.9 and 5.2 years for capital recovery, respectively. It is concluded that the current energy price policies hinder the promotion of installing CHP and CCHP systems and, the policy of selling electricity to utility as well as eliminating subsidies are prerequisites to successful widespread utilization of such systems. (author)

  11. Modelling of a CHP SOFC system fed with biogas from anaerobic digestion of municipal waste integrated with solar collectors and storage unit

    Directory of Open Access Journals (Sweden)

    Domenico Borello

    2012-12-01

    Full Text Available The paradigm of the sustainable energy community is recognized as the future energy approach due to its economical, technical and environmental benefits. Future systems should integrate renewable energy systems applying a “community-scale” approach to maximize energy performances, while minimizing environmental impacts. Efforts have to be directed toward the promotion of integrated technical systems needed to expand the use of renewable energy resources, to build sustainable local and national energy networks, to guarantee distribution systems for urban facilities and to reduce pollution. In this framework poly-generation is a promising design perspective, for building and district scale applications, in particular where different types of energy demand are simultaneously present and when sufficient energy intensity justifies investments in smart grids and district heating networks. In situ anaerobic digestion of biomass and organic waste has the potential to provide sustainable distributed generation of electric power together with a viable solution for the disposal of municipal solid wastes. A thermal recovery system can provide the heat required for district-heating. The system analysed is a waste-to-energy combined heat and power (CHP generation plant that perfectly fits in the sustainable energy community paradigm. The power system is divided in the following sections: a a mesophilic - single phase anaerobic digestion of Organic Fraction of Municipal Solid Waste for biogas production; b a fuel treatment section with desulphurizer and pre-reformer units; c a Solid Oxide Fuel Cell (SOFC for CHP production; d a solar collector integrated system(integrated storage system - ISS. An integrated TRNSYS/ASPEN Plus model for simulating the power system behaviour during a typical reference period (day or year was developed and presented. The proposed ISS consists of a solar collector integrated with storage systems system designed to

  12. PERFORMANCE ANALYSIS OF l kW RESIDENTIAL SOFC-CHP SYSTEM%1kW家用SOFC-CHP系统建模及性能分析

    Institute of Scientific and Technical Information of China (English)

    徐晗; 党政; 白博峰

    2011-01-01

    A combined heating and power system (CHP) driven by natrual gas was established based on solid oxide fuel cell (SOFC), relevant SOFC heat and mass transfer equations as well as electrochemical equations were deduced, and component models were built and solved by FORTRAN as a tool to predict the system performance of a 1 kW residential SOFC-CHP system. The results indicate that the system efficiency is much higher than the generating efficiency of SOFC under the design-point condition. A maximum value of electric power appears with the increase of the inlet fuel flow, fuel utilization and electric efficiency decrease, system cogeneration efficiency experiences a rising trend, and the cell temperature gradient distribution becomes growingly even. Reducing the excess air ratio could enhance the system performance.The above conclusions are very useful for the design and optimization of the residential SOFC-CHP system.%构建一个以天然气为燃料的SOFC-CHP系统,推导SOFC传热传质及电化学方程,建立各个组件的数学模型,编写计算程序,对发电功率为1kW的家用SOFC-CHP系统在设计工况下进行性能模拟并探讨不同系统参数对性能的影响.计算结果表明:在设计工况下,系统热电联供效率远高于电池单独发电的效率;此外,随着燃料入口流量的增大,系统发电功率存在一个最大值,燃料利用率与发电效率不断减小,系统热电联供效率不断增大,SOFC的温度梯度分布则越来越平缓;同时发现降低过量空气系数可以提高该CHP系统的性能.

  13. Energy Analysis and Multi-Objective Optimization of an Internal Combustion Engine-Based CHP System for Heat Recovery

    Directory of Open Access Journals (Sweden)

    Abdolsaeid Ganjehkaviri

    2014-10-01

    Full Text Available A comprehensive thermodynamic study is conducted of a diesel based Combined Heat and Power (CHP system, based on a diesel engine and an Organic Rankine Cycle (ORC. Present research covers both energy and exergy analyses along with a multi-objective optimization. In order to determine the irreversibilities in each component of the CHP system and assess the system performance, a complete parametric study is performed to investigate the effects of major design parameters and operating conditions on the system’s performance. The main contribution of the current research study is to conduct both exergy and multi-objective optimization of a system using different working fluid for low-grade heat recovery. In order to conduct the evolutionary based optimization, two objective functions are considered in the optimization; namely the system exergy efficiency, and the total cost rate of the system, which is a combination of the cost associated with environmental impact and the purchase cost of each component. Therefore, in the optimization approach, the overall cycle exergy efficiency is maximized satisfying several constraints while the total cost rate of the system is minimized. To provide a better understanding of the system under study, the Pareto frontier is shown for multi-objective optimization and also an equation is derived to fit the optimized point. In addition, a closed form relationship between exergy efficiency and total cost rate is derived.

  14. The C. elegans Chp/Wrch Ortholog CHW-1 Contributes to LIN-18/Ryk and LIN-17/Frizzled Signaling in Cell Polarity.

    Directory of Open Access Journals (Sweden)

    Ambrose R Kidd

    Full Text Available Wnt signaling controls various aspects of developmental and cell biology, as well as contributing to certain cancers. Expression of the human Rho family small GTPase Wrch/RhoU is regulated by Wnt signaling, and Wrch and its paralog Chp/RhoV are both implicated in oncogenic transformation and regulation of cytoskeletal dynamics. We performed developmental genetic analysis of the single Caenorhabditis elegans ortholog of Chp and Wrch, CHW-1. Using a transgenic assay of the distal tip cell migration, we found that wild-type CHW-1 is likely to be partially constitutively active and that we can alter ectopic CHW-1-dependent migration phenotypes with mutations predicted to increase or decrease intrinsic GTP hydrolysis rate. The vulval P7.p polarity decision balances multiple antagonistic Wnt signals, and also uses different types of Wnt signaling. Previously described cooperative Wnt receptors LIN-17/Frizzled and LIN-18/Ryk orient P7.p posteriorly, with LIN-17/Fz contributing approximately two-thirds of polarizing activity. CHW-1 deletion appears to equalize the contributions of these two receptors. We hypothesize that CHW-1 increases LIN-17/Fz activity at the expense of LIN-18/Ryk, thus making the contribution of these signals unequal. For P7.p to polarize correctly and form a proper vulva, LIN-17/Fz and LIN-18/Ryk antagonize other Wnt transmembrane systems VANG-1/VanGogh and CAM-1/Ror. Our genetic data suggest that LIN-17/Fz represses both VANG-1/VanGogh and CAM-1/Ror, while LIN-18/Ryk represses only VANG-1. These data expand our knowledge of a sophisticated signaling network to control P7.p polarity, and suggests that CHW-1 can alter ligand gradients or receptor priorities in the system.

  15. The C. elegans Chp/Wrch Ortholog CHW-1 Contributes to LIN-18/Ryk and LIN-17/Frizzled Signaling in Cell Polarity.

    Science.gov (United States)

    Kidd, Ambrose R; Muñiz-Medina, Vanessa; Der, Channing J; Cox, Adrienne D; Reiner, David J

    2015-01-01

    Wnt signaling controls various aspects of developmental and cell biology, as well as contributing to certain cancers. Expression of the human Rho family small GTPase Wrch/RhoU is regulated by Wnt signaling, and Wrch and its paralog Chp/RhoV are both implicated in oncogenic transformation and regulation of cytoskeletal dynamics. We performed developmental genetic analysis of the single Caenorhabditis elegans ortholog of Chp and Wrch, CHW-1. Using a transgenic assay of the distal tip cell migration, we found that wild-type CHW-1 is likely to be partially constitutively active and that we can alter ectopic CHW-1-dependent migration phenotypes with mutations predicted to increase or decrease intrinsic GTP hydrolysis rate. The vulval P7.p polarity decision balances multiple antagonistic Wnt signals, and also uses different types of Wnt signaling. Previously described cooperative Wnt receptors LIN-17/Frizzled and LIN-18/Ryk orient P7.p posteriorly, with LIN-17/Fz contributing approximately two-thirds of polarizing activity. CHW-1 deletion appears to equalize the contributions of these two receptors. We hypothesize that CHW-1 increases LIN-17/Fz activity at the expense of LIN-18/Ryk, thus making the contribution of these signals unequal. For P7.p to polarize correctly and form a proper vulva, LIN-17/Fz and LIN-18/Ryk antagonize other Wnt transmembrane systems VANG-1/VanGogh and CAM-1/Ror. Our genetic data suggest that LIN-17/Fz represses both VANG-1/VanGogh and CAM-1/Ror, while LIN-18/Ryk represses only VANG-1. These data expand our knowledge of a sophisticated signaling network to control P7.p polarity, and suggests that CHW-1 can alter ligand gradients or receptor priorities in the system. PMID:26208319

  16. Future market relevance of CHP installations with electrical ratings from 1 to 1000 kW; Zukuenftige Marktbedeutung von WKK-Anlagen mit 1 - 1000 kW elektrischer Leistung

    Energy Technology Data Exchange (ETDEWEB)

    Eicher, H.; Rigassi, R.

    2003-12-15

    This report for the Swiss Federal Office of Energy (SFOE) discusses the future market relevance of combined heat and power (CHP) installations with electrical ratings from 1 to 1000 kW. Developments over the past ten years are reviewed. Important reductions in the price of motor-driven CHP units and the price of the electrical power produced are noted and commented on. The technical market potential of CHP units and the degree to which this potential has been implemented are commented on. Work done, including CHP implementation in the industrial, commercial and residential areas, is commented on. Future developments both in the technical area as well as in commercial areas are commented on. Micro-gas-turbine based CHP systems are also discussed, as are fuel-cell based systems in both the higher and lower capacity power generation area. The prospects for CHP systems in general in the electricity generation area are discussed

  17. Mapping and disruption of the chpB locus in Escherichia coli.

    OpenAIRE

    Masuda, Y; Ohtsubo, E

    1994-01-01

    The chpB locus is a chromosomal homolog of the pem locus, which is responsible for stable maintenance of plasmid R100 within the host cells. Like pem, chpB codes for two genes, chpBK and chpBI, encoding a growth inhibitor and a suppressor for the killing action of the ChpBK protein, respectively. Here, we determined the precise location of the chpB locus, which is linked to ileR and ppa in the order ileR-chpB-ppa, at 95.7 min on the map of Escherichia coli. We then constructed mutants with an...

  18. Design and analysis of permanent magnet moving coil type generator used in a micro-CHP generation system

    Science.gov (United States)

    Oros Pop, Susana Teodora; Berinde, Ioan; Vadan, Ioan

    2015-12-01

    This paper presents the design and analysis of a permanent magnet moving coil type generator driven by a free piston Stirling engine. This assemble free piston Stirling engine - permanent magnet moving coil type generator will be used in a combined heat and power (CHP) system for producing heat and power in residential area. The design procedure for moving coil type linear generator starts from the rated power imposed and finally uses the Faraday law of induction. The magneto-static magnetic field generated by permanent magnets is analyzed by means of Reluctance method and Finite Element Method in order to evaluate the magnetic flux density in the air gap, which is a design data imposed in the design stage, and the results are compared.

  19. Fuel cells and electrolysers in future energy systems

    DEFF Research Database (Denmark)

    Mathiesen, Brian Vad

    systems with large shares of intermittent renewable energy than in conventional en‐ ergy systems. Thus, they are important measures on the path towards future 100 per cent renewable energy systems. In locally distributed CHP plants with district heating grids, fuel cells are especially promis‐ ing...... in individual households are not suitable for renewable en‐ ergy systems. This is due to the high losses associated with the conversion to hydrogen and the lower regulation abilities of such systems. In a short‐term perspective, natural gas mi‐ cro‐fuel cell CHP may spread the CHP production more than locally......‐efficient option in terms of using such scarce resources. Heat pumps are more fuel and cost‐efficient options in terms of meeting the heat demand in individual houses. Both fuel cell and battery electric vehicles are more efficient options than conventional internal combustion engine vehicles. In terms...

  20. Evaluation of the environmental sustainability of a micro CHP system fueled by low-temperature geothermal and solar energy

    International Nuclear Information System (INIS)

    Highlights: • Binary, ORC technology avoids CO2, but raises questions about environmental impact. • We proposed a micro-size system that combines geothermal energy with solar energy. • The small scale and the solar energy input edges the energy profitability. • The system’s performance is appreciable if applied to existing wells. • The feasibility of exploiting abandoned wells is preliminarily evaluated. - Abstract: In this paper we evaluate the environmental sustainability of a small combined heat and power (CHP) plant operating through an Organic Rankine Cycle (ORC). The heat sources of the system are from geothermal energy at low temperature (90–95 °C) and solar energy. The designed system uses a solar field composed only of evacuated, non-concentrating solar collectors, and work is produced by a single turbine of 50 kW. The project addresses an area of Tuscany, but it could be reproduced in areas where geothermal energy is extensively developed. Therefore, the aim is to exploit existing wells that are either unfit for high-enthalpy technology, abandoned or never fully developed. Furthermore, this project aims to aid in downsizing the geothermal technology in order to reduce the environmental impact and better tailor the production system to the local demand of combined electric and thermal energy. The environmental impact assessment was performed through a Life Cycle Analysis and an Exergy Life Cycle Analysis. According to our findings the reservoir is suitable for a long-term exploitation of the designed system, however, the sustainability and the energy return of this latter is edged by the surface of the heat exchanger and the limited running hours due to the solar plant. Therefore, in order to be comparable to other renewable resources or geothermal systems, the system needs to develop existing wells, previously abandoned

  1. Using Cost-Effectiveness Tests to Design CHP Incentive Programs

    Energy Technology Data Exchange (ETDEWEB)

    Tidball, Rick [ICF International, Fairfax, VA (United States)

    2014-11-01

    This paper examines the structure of cost-effectiveness tests to illustrate how they can accurately reflect the costs and benefits of CHP systems. This paper begins with a general background discussion on cost-effectiveness analysis of DER and then describes how cost-effectiveness tests can be applied to CHP. Cost-effectiveness results are then calculated and analyzed for CHP projects in five states: Arkansas, Colorado, Iowa, Maryland, and North Carolina. Based on the results obtained for these five states, this paper offers four considerations to inform regulators in the application of cost-effectiveness tests in developing CHP programs.

  2. Development and evaluation of a biomass-fired micro-scale CHP with organic rankine cycle

    OpenAIRE

    Shao, Yingjuan

    2011-01-01

    Combined Heat and Power Generation (CHP) or cogeneration has been considered worldwide as the major alternative to traditional energy systems in terms of signi ticant energy saving and environmental conservation. A renewable energy resource-fuelled CHP would deliver even more environmental benefits than a fossil tuel-driven CHP. Biomass is one of the renewable energy resources that plays an important role to the world primary energy supplies and can be used to fuel CHP systems. Many medium- a...

  3. Biological Properties and Cell Tropism of Chp2, a Bacteriophage of the Obligate Intracellular Bacterium Chlamydophila abortus

    OpenAIRE

    Everson, J. S.; Garner, S. A.; Fane, B.; Liu, B.-L.; Lambden, P R; Clarke, I N

    2002-01-01

    A number of bacteriophages belonging to the Microviridae have been described infecting chlamydiae. Phylogenetic studies divide the Chlamydiaceae into two distinct genera, Chlamydia and Chlamydophila, containing three and six different species, respectively. In this work we investigated the biological properties and host range of the recently described bacteriophage Chp2 that was originally discovered in Chlamydophila abortus. The obligate intracellular development cycle of chlamydiae has prec...

  4. Regional Energy Systems with Retrofitted Combined Heat and Power (CHP) Plants

    OpenAIRE

    Han, Song

    2012-01-01

    Fossil fuel depletion, economic development, urban expansion and climate change present tough challenges to municipal- and regional-scale energy systems. Regional energy system planning, including waste treatment, renewable energy supply, energy efficiency, and climate change, are considered essential to meet these challenges and move toward a sustainable society. This thesis includes studies on energy system from municipal waste, potential for a fossil fuel-independent regional energy system...

  5. Adapting CHP Software to suit the modelling of heat pump and refrigeration systems

    NARCIS (Netherlands)

    Verschoor, M.J.E.

    1998-01-01

    The role of heat pumps and refrigeration machines as integrated parts of energy supply systems is increasing as a result of the search for systems which supply the desired amounts and types of energy in an energy-efficient manner. Tools to support engineers in designing, analysing and optimising suc

  6. Modelling of energy systems with a high percentage of CHP and wind power

    DEFF Research Database (Denmark)

    Lund, Henrik; Münster, E.

    2003-01-01

    The paper presents the energy system analysis model EnergyPLAN, which has been used to analyse the integration of large scale wind power into the national Danish electricity system. The main purpose of the EnergyPLAN model is to design suitable national energy planning strategies by analysing the...

  7. Performance comparison between partial oxidation and methane steam for SOFC micro-CHP systems

    DEFF Research Database (Denmark)

    Liso, Vincenzo; Olesen, Anders Christian; Nielsen, Mads Pagh;

    2011-01-01

    and Partial Oxidation and recirculation of anode and cathode gas. The comparative analysis among the different configurations will lead us to conclude that maximum efficiency is achieved when cathode and anode gas recirculation are used along with steam methane reforming. Further Steam Methane Reforming...... process produces a higher electrical system efficiency compared to Partial oxidation reforming process. Efficiency is affected when running the system in part load mode mainly due to heat loss, additional natural gas supplied to the burner to satisfy the required heat demand inside the system, and ejector...... efficiency drop in the recirculation system. Due to high temperature of operation heat loss strongly affects the system efficiency especially at part load operation....

  8. Demonstration of Next-Generation PEM CHP Systems for Global Markets Using PBI Membrane Technology

    Energy Technology Data Exchange (ETDEWEB)

    Vogel, John [Plug Power Inc., Latham, NY (United States); Fritz Intwala, Katrina [Plug Power Inc., Latham, NY (United States)

    2009-08-01

    Plug Power and BASF have conducted eight years of development work prior to this project, demonstrating the potential of PBI membranes to exceed many DOE technical targets. This project consisted of; 1.The development of a worldwide system architecture; 2.Stack and balance of plant module development; 3.Development of an improved, lower cost MEA electrode; 4.Receipt of an improved MEA from the EU consortium; 5.Integration of modules into a system; and 6.Delivery of system to EU consortium for additional integration of technologies and testing.

  9. Potential of ORC Systems to Retrofit CHP Plants in Wastewater Treatment Stations

    Directory of Open Access Journals (Sweden)

    Ricardo Chacartegui

    2013-12-01

    Full Text Available Wastewater treatment stations take advantage of the biogas produced from sludge in anaerobic digesters to generate electricity (reciprocating gas engines and heat (cooling water and engine exhaust gases. A fraction of this electricity is used to operate the plant while the remaining is sold to the grid. Heat is almost entirely used to support the endothermic anaerobic digestion and a minimum fraction of it is rejected to the environment at a set of fan coolers. This generic description is applicable to on-design conditions. Nevertheless, the operating conditions of the plant present a large seasonal variation so it is commonly found that the fraction of heat rejected to the atmosphere increases significantly at certain times of the year. Moreover, the heat available in the exhaust gases of the reciprocating engine is at a very high temperature (around 650 oC, which is far from the temperature at which heat is needed for the digestion of sludge (around 40 oC in the digesters. This temperature difference offers an opportunity to introduce an intermediate system between the engines and the digesters that makes use of a fraction of the available heat to convert it into electricity. An Organic Rankine Cycle (ORC with an appropriate working fluid is an adequate candidate for these hot/cold temperature sources. In this paper, the techno-economic effect of adding an Organic Rankine Cycle as the intermediate system of an existing wastewater treatment station is analysed. On this purpose, different working fluids and system layouts have been studied for a reference wastewater treatment station giving rise to optimal systems configurations. The proposed systems yield very promising results with regard to global efficiency and electricity production (thermodynamically and economically.

  10. CHP2 gene expression and quantitation in Egyptian patients with acute leukemia

    OpenAIRE

    Amira Ahmed Hammam; Hisham Hasan Eissa; Mohamed Roshdy El Masry; Sarah Mahmoud

    2014-01-01

    Aim: CHP2 (calcineurin B homologous protein 2) is identified as a tumor-associated antigen highly expressed in different malignancies. It plays a critical role in cancer cell development, proliferation, motility and survival. It is suggested that the human tumor related gene CHP2 expression in leukemia primary cells and leukemia cell lines significantly increase, which may play an important role in growth process of leukemia cells. Methods: In this study, the expression of CHP2 gene was an...

  11. Specification of Selected Performance Monitoring and Commissioning Verification Algorithms for CHP Systems

    Energy Technology Data Exchange (ETDEWEB)

    Brambley, Michael R.; Katipamula, Srinivas

    2006-10-06

    Pacific Northwest National Laboratory (PNNL) is assisting the U.S. Department of Energy (DOE) Distributed Energy (DE) Program by developing advanced control algorithms that would lead to development of tools to enhance performance and reliability, and reduce emissions of distributed energy technologies, including combined heat and power technologies. This report documents phase 2 of the program, providing a detailed functional specification for algorithms for performance monitoring and commissioning verification, scheduled for development in FY 2006. The report identifies the systems for which algorithms will be developed, the specific functions of each algorithm, metrics which the algorithms will output, and inputs required by each algorithm.

  12. Development of a Transient Model of a Stirling-Based CHP System

    Directory of Open Access Journals (Sweden)

    Antón Cacabelos

    2013-06-01

    Full Text Available Although the Stirling engine was invented in 1816, this heat engine still continues to be investigated due to the variety of energy sources that can be used to power it (e.g., solar energy, fossil fuels, biomass, and geothermal energy. To study the performance of these machines, it is necessary to develop and simulate models under different operating conditions. In this paper, we present a one-dimensional dynamic model based on components from Trnsys: principally, a lumped mass and a heat exchanger. The resulting model is calibrated using GenOpt. Furthermore, the obtained model can be used to simulate the machine both under steady-state operation and during a transient response. The results provided by the simulations are compared with data measured in a Stirling engine that has been subjected to different operating conditions. This comparison shows good agreement, indicating that the model is an appropriate method for transient thermal simulations. This new proposed model requires few configuration parameters and is therefore easily adaptable to a wide range of commercial models of Stirling engines. A detailed analysis of the system results reveals that the power is directly related to the difference of temperatures between the hot and cold sources during the transient and steady-state processes.

  13. Economic potentials of CHP connected to district heat systems in Germany. Implementation of the EU Efficiency Directive; Wirtschaftliche Potenziale der waermeleitungsgebundenen Siedlungs-KWK in Deutschland. Umsetzung der EU-Energieeffizienzrichtlinie

    Energy Technology Data Exchange (ETDEWEB)

    Eikmeier, Bernd [Fraunhofer-Institut fuer Fertigungstechnik und Angewandte Materialforschung IFAM, Bremen (Germany). Organisationseinheit Systemanalyse; Bremen Univ. (Germany)

    2015-07-01

    The EU Efficiency Directive (2012/27/EU) is requiring all member states to carry out an evaluation of the potential for highly efficient CHP and the efficient use of district heating and cooling by December 2015. The German Federal Ministry of Economic Affairs and Energy appointed this task to the Fraunhofer Institute for Manufacturing and Advanced Materials, division for Energy Systems Analysis (formerly Bremer Energie Institut) in conjunction with other partners. The results for the sector district- and communal heating with CHP, sub-sectors private households, trade and services industry, are presented in this article.

  14. A new approach for near real-time micro-CHP management in the context of power system imbalances – A case study

    International Nuclear Information System (INIS)

    Highlights: • An aggregator consisting of micro-CHPs was proposed. • A near-real time balance optimization was developed. • A case study that resembles the actual situation of the Belgian energy market is studied. • Using the near-real time balance optimization a cost decrease between 2.5% and 5% can be achieved. - Abstract: In order to ensure reliable operation of the electric grid, it is required to keep the balance between total generation and consumption of power in real-time. This task is performed by the transmission system operator. Nowadays, with the large penetration of intermittent generation on the electric grid there is a need to increase the flexibility of the system in order to ensure the balance. The present study develops a methodology to provide near real-time balancing services making use of an aggregation of micro-CHP devices. The controller of the aggregator bids electricity into the day-ahead market using the expected heat demand and spot market prices. The main focus of this work is on the near real-time optimization which is performed during the actual day. This optimization provides the opportunity to obtain extra profits by rescheduling the operation of the aggregator. The rescheduling is done in order to compensate the total system imbalance. To achieve this, every time step, the aggregator evaluates the system demand for up or down regulation and decides if it is profitable to adjust its position to provide balancing services to the power system. The methodology is applied to a case study that resembles the actual situation of the energy market and CHP installations in Belgium. The results show that using the near real-time balancing optimization a total cost decrease of 5% can be achieved depending on the season. This conclusion is valid even if there is an increase of the gas prices and if the actual governmental support on CHPs is not taken into account

  15. Business Case for a Micro-Combined Heat and Power Fuel Cell System in Commercial Applications

    Energy Technology Data Exchange (ETDEWEB)

    Brooks, Kriston P.; Makhmalbaf, Atefe; Anderson, David M.; Amaya, Jodi P.; Pilli, Siva Prasad; Srivastava, Viraj; Upton, Jaki F.

    2013-10-30

    Combined heat and power fuel cell systems (CHP-FCSs) provide consistent electrical power and hot water with greater efficiency and lower emissions than alternative sources. These systems can be used either as baseload, grid-connected, or as off-the-grid power sources. This report presents a business case for CHP-FCSs in the range of 5 to 50 kWe. Systems in this power range are considered micro-CHP-FCS. For this particular business case, commercial applications rather than residential or industrial are targeted. To understand the benefits of implementing a micro-CHP-FCS, the characteristics that determine their competitive advantage must first be identified. Locations with high electricity prices and low natural gas prices are ideal locations for micro-CHP-FCSs. Fortunately, these high spark spread locations are generally in the northeastern area of the United States and California where government incentives are already in place to offset the current high cost of the micro-CHP-FCSs. As a result of the inherently high efficiency of a fuel cell and their ability to use the waste heat that is generated as a CHP, they have higher efficiency. This results in lower fuel costs than comparable alternative small-scale power systems (e.g., microturbines and reciprocating engines). A variety of markets should consider micro-CHP-FCSs including those that require both heat and baseload electricity throughout the year. In addition, the reliable power of micro-CHP-FCSs could be beneficial to markets where electrical outages are especially frequent or costly. Greenhouse gas emission levels from micro-CHP-FCSs are 69 percent lower, and the human health costs are 99.9 percent lower, than those attributed to conventional coal-fired power plants. As a result, FCSs can allow a company to advertise as environmentally conscious and provide a bottom-line sales advantage. As a new technology in the early stages of adoption, micro-CHP-FCSs are currently more expensive than alternative

  16. Is micro-CHP price controllable under price signal controlled Virtual Power Plants?

    DEFF Research Database (Denmark)

    You, Shi; Træholt, Chresten; Poulsen, Bjarne

    2011-01-01

    As micro-combined heat and power (micro-CHP) systems move towards mass deployment together with other kinds of distributed energy resources (DER), an increasing emphasis has been placed on how to coordinate such a large diversified DER portfolio in an efficient way by the Virtual Power Plant (VPP...... three different micro-CHP systems to investigate the feasibility of being controlled by price. Such analysis is relevant for both controller designs for micro-CHP systems and VPP related operations. The results indicate that controlling the micro-CHP systems by price is feasible but could result in...

  17. CHP plant reduces grain whisky costs

    Energy Technology Data Exchange (ETDEWEB)

    Forrester, R.

    1989-04-01

    Scottish Grain Distillers Limited operate one of the largest grain whisky spirit production units in Scotland at Port Dundas Distillery, Glasgow. In 1972, a treatment plant for the distillery residues was installed. This was a major user of steam and fuelled by oil. In 1983, prompted by spiralling oil price rises, changes in the plant were initiated resulting in a significant move away from steam to electricity as the main source of energy and replacing oil by gas as the boiler fuel. To further improve the economics, an on-site gas turbine combined heat and power (CHP) system has been installed, any excess power being exported to the national grid. Estimated savings achieved by the CHP system point to a payback of 5.2 years on the gross investment capital. (U.K.).

  18. Proliferation of Cultured Mouse Choroid Plexus Epithelial Cells

    OpenAIRE

    Barkho, Basam Z.; Monuki, Edwin S.

    2015-01-01

    The choroid plexus (ChP) epithelium is a multifunctional tissue found in the ventricles of the brain. The major function of the ChP epithelium is to produce cerebrospinal fluid (CSF) that bathes and nourishes the central nervous system (CNS). In addition to the CSF, ChP epithelial cells (CPECs) produce and secrete numerous neurotrophic factors that support brain homeostasis, such as adult hippocampal neurogenesis. Accordingly, damage and dysfunction to CPECs are thought to accelerate and inte...

  19. Elimination of restraints on the propagation of combined heat and power (CHP) generation systems in Switzerland; Beseitigung von Hemmnissen bei der Verbreitung von Waermekraftkopplung (WKK) in der Schweiz

    Energy Technology Data Exchange (ETDEWEB)

    Rieder, S.; Landis, F. [Interface Politikstudien Forschung Beratung, Luzern (Switzerland); Lienhard, A.; Marti Locher, F. [Universitaet Bern, Kompetenzzentrum fuer Public Management (KPM), Bern (Switzerland); Krummenacher, S. [Enerprice Partners AG, Technopark Luzern, Root Laengenbold (Switzerland)

    2009-04-15

    This report for the Swiss Federal Office of Energy (SFOE) discusses the results of study initiated by the SFOE that was to investigate the reasons for the low level of proliferation of CHP technology in Switzerland. The two main questions asked - which factors inhibit the use of CHP in particular application areas and which energy-policy measures can remove such obstacles - are discussed. The use of CHP in various areas of application from waste incineration plants through to units used in residential buildings is analysed and commented on. Recommendations on measures that can be taken to enhance the use of CHP are discussed. Three strategy variants available to the public services area are presented and discussed. It is noted that a consensus between players in the technical and political areas is necessary

  20. Development of a CHP/DH system for the new town of Parand: An opportunity to mitigate global warming in Middle East

    International Nuclear Information System (INIS)

    As a result of the worldwide concern about global warming, projects that target reduction of greenhouse gas emissions have gained a lot of interest. The idea of this paper is to recover exhaust hot gases of an existing gas turbine power plant to meet dynamic thermal energy requirements of a residential area (the new town of Parand) situated in the suburb of Tehran, and also use the rest of the heat source potential to feed a steam turbine cycle. In close proximity to this town, there are two GT plants: Parand (954 MWe) and Rudeshur (790 MWe). For handling the CHP/STC/DH plant, two methods are considered along with thermal load following operation strategy: maximum power generation (MPG) and minimum fuel consumption (MFC). Then, the alternatives are compared in terms of annual PES, CO2 abatement and NPV. For the best design from environmental viewpoint (Parand CHP-B), PES, CO2 abatement and NPV are calculated to be 27.31%, 2.56 million tons and 1491 million dollar, respectively. -- Highlights: • To propose a technical and financial methodology to evaluate CHP/DH projects. • To address environmental advantages of CHPs with conventional plants. • To present practical operation strategies to increase benefits of CHP/DH plants. • To report/compare benefits of various CHP/DH alternatives for a case study in Iran. • To conduct a comprehensive energy analysis of proposed CHP/DH design options

  1. Biomass CHP based on a Stirling engine

    Energy Technology Data Exchange (ETDEWEB)

    Cowburn, D.A.; Dando, R.L.

    1997-12-31

    Combined heat and power (CHP) schemes offer a means of converting fuel to useful energy with much higher efficiencies (up to 80 percent) compared to electricity generating stations (efficiencies <36 percent). This has led to many EEC member states, including the UK, and other industrial countries encouraging the use of CHP. At the smaller scale (<500 kWe) steam based systems have generally proven too costly to provide solid fuel with an opportunity to exploit this potentially attractive CHP market sector. The Stirling engine offers a technology which can produce mechanical power from solid fuels without the need to raise steam. This project has been directed towards producing a Stirling engine design capable of producing an output of 150 kW{sub e} from solid fuel. The participants in the projects, CRE Group Ltd., Basys Marine Ltd. (formerly Cray Marine) and Gamos Ltd., brought together a wide range of experience in the areas of gasification, combustion, heat transfer, Stirling engine technology and high precision engineering. A novel form of low pressure nitrogen charged Stirling engine has been designed specifically for stationary applications. This avoided the drawbacks of high pressures with H{sub e} or H used as the working fluids and consequent requirement for exotic sealing arrangements, which have been associated with previous Stirling engine`s aimed primarily at the automotive market. (author)

  2. CHP plant Legionowo Poland - Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-12-01

    In 1997, a new Energy Law was passed in Poland. An important element of the law is that local energy planning is made obligatory. The law describes obligatory tasks and procedures for Polish municipalities related to planning and organisation of the energy sector. With the objective of supporting the Polish municipalities in their obligations according to the energy law of 1997, the project 'Energy Planning in Poland at Municipal Level - Support to Decision Makers' was launched. As part of the project, Municipal Guideline Reports have been elaborated for three model municipalities. These guidelines present the basis for the Energy Supply Plans in these municipalities. For the city of Legionowo, the following was recommended: 1. The planning processes initiated during the project should be continues/followed up, 2. Master Plan for the district heating system should be prepared, 3. The possibilities of establishment of a major natural gas-fired CHP plant of the Combined Cycle type should be investigated. The present report is the final Master Plan based on the following reports: Master Plan for Legionowo - Status Report; Master Plan for Legionowo - Hydraulic Analysis; CHP Plant Legionowo Poland - CHP Feasibility Analysis. The final Master Plan describes the status in the DH Company in Legionowo, possible improvements and an investment plan for the selected scenario. (BA)

  3. Optimization of a High Temperature PEMFC micro-CHP System by Formulation and Application of a Process Integration Methodology

    DEFF Research Database (Denmark)

    Arsalis, Alexandros; Nielsen, Mads Pagh; Kær, Søren Knudsen

    2013-01-01

    . It consists of a fuel cell stack, a fuel processing subsystem, heat exchangers, and balance-of-plant components. The optimization methodology involves system optimization attempting to maximize the net electrical efficiency, and then by use of a mixed integer nonlinear programming (MINLP) problem formulation......, the heat exchange network (HEN) annual cost is minimized. The results show the high potential of the proposed model since high efficiencies are accomplished. The net electrical efficiency and total system efficiency, based on lower heating value (LHV), are 35.2% and 91.1%, respectively. The minimized total...

  4. Development and Testing of the Advanced CHP System Utilizing the Off-Gas from the Innovative Green Coke Calcining Process in Fluidized Bed

    Energy Technology Data Exchange (ETDEWEB)

    Chudnovsky, Yaroslav; Kozlov, Aleksandr

    2013-08-15

    Green petroleum coke (GPC) is an oil refining byproduct that can be used directly as a solid fuel or as a feedstock for the production of calcined petroleum coke. GPC contains a high amount of volatiles and sulfur. During the calcination process, the GPC is heated to remove the volatiles and sulfur to produce purified calcined coke, which is used in the production of graphite, electrodes, metal carburizers, and other carbon products. Currently, more than 80% of calcined coke is produced in rotary kilns or rotary hearth furnaces. These technologies provide partial heat utilization of the calcined coke to increase efficiency of the calcination process, but they also share some operating disadvantages. However, coke calcination in an electrothermal fluidized bed (EFB) opens up a number of potential benefits for the production enhancement, while reducing the capital and operating costs. The increased usage of heavy crude oil in recent years has resulted in higher sulfur content in green coke produced by oil refinery process, which requires a significant increase in the calcinations temperature and in residence time. The calorific value of the process off-gas is quite substantial and can be effectively utilized as an “opportunity fuel” for combined heat and power (CHP) production to complement the energy demand. Heat recovered from the product cooling can also contribute to the overall economics of the calcination process. Preliminary estimates indicated the decrease in energy consumption by 35-50% as well as a proportional decrease in greenhouse gas emissions. As such, the efficiency improvement of the coke calcinations systems is attracting close attention of the researchers and engineers throughout the world. The developed technology is intended to accomplish the following objectives: - Reduce the energy and carbon intensity of the calcined coke production process. - Increase utilization of opportunity fuels such as industrial waste off-gas from the novel

  5. Three novel NY-ESO-1 epitopes bound to DRB1*0803, DQB1*0401 and DRB1*0901 recognized by CD4 T cells from CHP-NY-ESO-1-vaccinated patients.

    Science.gov (United States)

    Mizote, Yu; Taniguchi, Taku; Tanaka, Kei; Isobe, Midori; Wada, Hisashi; Saika, Takashi; Kita, Shoichi; Koide, Yukari; Uenaka, Akiko; Nakayama, Eiichi

    2010-07-19

    Three novel NY-ESO-1 CD4 T cell epitopes were identified using PBMC obtained from patients who were vaccinated with a complex of cholesterol-bearing hydrophobized pullulan (CHP) and NY-ESO-1 protein (CHP-NY-ESO-1). The restriction molecules were determined by antibody blocking and using various EBV-B cells with different HLA alleles as APC to present peptides to CD4 T cells. The minimal epitope peptides were determined using various N- and C-termini truncated peptides deduced from 18-mer overlapping peptides originally identified for recognition. Those epitopes were DRB1*0901-restricted NY-ESO-1 87-100, DQB1*0401-restricted NY-ESO-1 95-107 and DRB1*0803-restricted NY-ESO-1 124-134. CD4 T cells used to determine those epitope peptides recognized EBV-B cells or DC that were treated with recombinant NY-ESO-1 protein or NY-ESO-1-expressing tumor cell lysate, suggesting that the epitope peptides are naturally processed. These CD4 T cells showed a cytokine profile with Th1 characteristics. Furthermore, NY-ESO-1 87-100 peptide/HLA-DRB1*0901 tetramer staining was observed. Multiple Th1-type CD4 T cell responses are beneficial for inducing effective anti-tumor responses after NY-ESO-1 protein vaccination.

  6. Decentralised CHP in a competitive market

    DEFF Research Database (Denmark)

    Lund, Henrik

    2004-01-01

    The article agues that decentralised CHP plants is an important part of energy supply in Denmark.......The article agues that decentralised CHP plants is an important part of energy supply in Denmark....

  7. Implementation of a TPV integrated boiler for micro-CHP in residential buildings

    International Nuclear Information System (INIS)

    Highlights: • A TPV integrated boiler for micro-CHP application is designed, tested and demonstrated. • Thermal radiation was emitted by a porous emitter in the TPV unit. • The electric output of four TPV cell modules connected in series is measured and characterized under various conditions. • 246.4 Electricity is generated at the emitter temperature of 1265 °C. • This study shows that TPV generation in boilers/furnaces is feasible for micro-CHP application in residential buildings. - Abstract: There is a growing interest in direct thermal-to-electric energy conversion using solid state devices such as thermophotovoltaic (TPV) generators. TPV devices convert thermal radiation from heat sources into electricity without involving any moving parts. TPV opens up possibility for efficient and stand-alone power generation in boilers and furnaces. In this paper, a TPV integrated boiler was designed, built and investigated for micro combined heat and power (micro-CHP) application in residential buildings. A full size gas fired residential boiler was used as a precursor for integration with TPV devices. Experiments were conducted with the prototype TPV boiler so as to evaluate various issues related to this new technology. The electric output of TPV modules installed in the boiler was characterized under different operating conditions. The TPV cell modules generated 246.4 W at an emitter temperature of 1265 °C, which would be enough to power the electrical components of the whole heating system. Moreover, such a TPV integrated boiler could be employed to form a micro-CHP system in residential homes, providing an effective means for primary energy savings, on-site power and energy security

  8. Techno-economic analysis of a coal-fired CHP based combined heating system with gas-fired boilers for peak load compensation

    International Nuclear Information System (INIS)

    Combined heat and power (CHP) plants dominate the heating market in China. With the ongoing energy structure reformation and increasing environmental concerns, we propose gas-fired boilers to be deployed in underperforming heating substations of heating networks for peak load compensation, in order to improve both energy efficiency and environmental sustainability. However, due to the relatively high price of gas, techno-economic analysis is required for evaluating different combined heating scenarios, characterized by basic heat load ratio (β). Therefore, we employ the dynamic economics and annual cost method to develop a techno-economic model for computing the net heating cost of the system, considering the current state of the art of cogeneration systems in China. The net heating cost is defined as the investment costs and operations costs of the system subtracted by revenues from power generation. We demonstrate the model in a real-life combined heating system of Daqing, China. The results show that the minimum net heating cost can be realized at β=0.75 with a cost reduction of 16.8% compared to coal heating alone. Since fuel cost is the dominating factor, sensitivity analyses on coal and gas prices are discussed subsequently. - Highlights: ► Combined heating systems comply with the energy structure reformation in China. ► We consider the current state of the art of cogeneration systems in China. ► Combined heating systems can be economically more feasible and sustainable. ► The net heating cost of a combined heating system is more sensitive to coal price. ► The optimal basic heat load ratio is more easily influenced by gas price.

  9. ANALYSIS OF CHP POTENTIAL AT FEDERAL SITES

    Energy Technology Data Exchange (ETDEWEB)

    HADLEY, S.W.

    2002-03-11

    This document was prepared at the request of the U.S. Department of Energy's (DOE's) Federal Energy Management Program (FEMP) under its Technical Guidance and Assistance and Project Financing Programs. The purpose was to provide an estimate of the national potential for combined heat and power (also known as CHP; cogeneration; or cooling, heating, and power) applications at federal facilities and the associated costs and benefits including energy and emission savings. The report provides a broad overview for the U.S. Department of Energy (DOE) and other agencies on when and where CHP systems are most likely to serve the government's best interest. FEMP's mission is to reduce the cost to and environmental impact of the federal government by advancing energy efficiency and water conservation, promoting the use of renewable energy, and improving utility management decisions at federal sites. FEMP programs are driven by its customers: federal agency sites. FEMP monitors energy efficiency and renewable energy technology developments and mounts ''technology-specific'' programs to make technologies that are in strong demand by agencies more accessible. FEMP's role is often one of helping the federal government ''lead by example'' through the use of advanced energy efficiency/renewable energy (EERE) technologies in its own buildings and facilities. CHP was highlighted in the Bush Administration's National Energy Policy Report as a commercially available technology offering extraordinary benefits in terms of energy efficiencies and emission reductions. FEMP's criteria for emphasizing a technology are that it must be commercially available; be proven but underutilized; have a strong constituency and momentum; offer large energy savings and other benefits of interest to federal sites and FEMP mission; be in demand; and carry sufficient federal market potential. As discussed in the report, CHP meets all

  10. Mississippi State University Cooling, Heating, and Power (Micro-CHP) and Bio-Fuel Center

    Energy Technology Data Exchange (ETDEWEB)

    Mago, Pedro [Mississippi State Univ., Mississippi State, MS (United States); Newell, LeLe [Mississippi State Univ., Mississippi State, MS (United States)

    2014-01-31

    Between 2008 and 2014, the U.S. Department of Energy funded the MSU Micro-CHP and Bio-Fuel Center located at Mississippi State University. The overall objective of this project was to enable micro-CHP (micro-combined heat and power) utilization, to facilitate and promote the use of CHP systems and to educate architects, engineers, and agricultural producers and scientists on the benefits of CHP systems. Therefore, the work of the Center focused on the three areas: CHP system modeling and optimization, outreach, and research. In general, the results obtained from this project demonstrated that CHP systems are attractive because they can provide energy, environmental, and economic benefits. Some of these benefits include the potential to reduce operational cost, carbon dioxide emissions, primary energy consumption, and power reliability during electric grid disruptions. The knowledge disseminated in numerous journal and conference papers from the outcomes of this project is beneficial to engineers, architects, agricultural producers, scientists and the public in general who are interested in CHP technology and applications. In addition, more than 48 graduate students and 23 undergraduate students, benefited from the training and research performed in the MSU Micro-CHP and Bio-Fuel Center.

  11. Study on CHP-induced cell apoptosis in hematopoietic malignancies%中药提取物诱导血液肿瘤细胞凋亡的初步研究

    Institute of Scientific and Technical Information of China (English)

    夏迪; 贾培敏; 马瑜珊; 童建华

    2012-01-01

    目的:观察中药提取物(CHP)对急性髓系白血病细胞Kasumi-1和滤泡状淋巴瘤细胞Su-DHL-4的诱导凋亡效应.方法:将浓度为50 μg/mL的CHP分别作用于Kasumi-1和Su-DHL-4细胞,观察细胞的生长状况与形态变化;应用流式细胞术检测磷脂酰丝氨酸的外翻、线粒体跨膜电位及凋亡抑制蛋白Bcl-2的表达变化情况.结果:Kasumi-1和Su-DHL-4细胞经50 μg/mL CHP处理后,生长均受到抑制,48 h时的生长抑制率分别为(69.45±7.21)%和(82.44±5.86)%,并可观察到典型的凋亡细胞.与对照组相比,CHP处理24 h后,2种细胞的Annexin V阳性率分别从(10.58±1.22)%和(4.30±0.52)%上升到(53.53.±6.07)%和(59.87±5.56)%,差异均有统计学意义(P<0.01);线粒体跨膜电位下降的细胞百分率从(6.67±0.64)%和(7.20±2.33)%上升到(31.13±1.80)%和(55.97±7.33)%,差异亦有统计学意义(P<0.01);此外,Su-DHL-4细胞中Bcl-2蛋白水平也有明显下降.结论:CHP能诱导急性髓系白血病细胞Kasumi-I和滤泡性淋巴瘤细胞Su-DHL-4发生凋亡.%Objective: To study the effect of CHP (a Chinese traditional medicine extract) on apoptosis of acute myeloid leukemia cell line Kasumi-1 and follicular lymphoma cell line Su-DHL-4. Methods: Kasumi-1 cells and Su-DHL-4 cells were treated respectively with CHP at the concentration of 50 μg/mL. The effect of CHP was evaluated by cell growth, cell morphology and markers of cell apoptosis. The plasma membrane translocation of phosphatidylserine, the mitochondrial transmembrane potential, and the expression of anti-apoptotic protein Bcl-2 were detected by flow cytometry. Results: CHP inhibited significantly the cell proliferation of Kasumi-1 cells and Su-DHL-4 cells. After 48 h treatment with CHP, the rates of growth inhibition of Kasumi-1 and Su-DHL-4 cells were (69.45 ±7.21)% and (82.44 ±5.86)% , respectively, and typical apoptotic cells could be observed. In addition, compared with the two control

  12. Feed-forward control of a solid oxide fuel cell system with anode offgas recycle

    Science.gov (United States)

    Carré, Maxime; Brandenburger, Ralf; Friede, Wolfgang; Lapicque, François; Limbeck, Uwe; da Silva, Pedro

    2015-05-01

    In this work a combined heat and power unit (CHP unit) based on the solid oxide fuel cell (SOFC) technology is analysed. This unit has a special feature: the anode offgas is partially recycled to the anode inlet. Thus it is possible to increase the electrical efficiency and the system can be operated without external water feeding. A feed-forward control concept which allows secure operating conditions of the CHP unit as well as a maximization of its electrical efficiency is introduced and validated experimentally. The control algorithm requires a limited number of measurement values and few deterministic relations for its description.

  13. Design and Optimization of an Integrated Biomass Gasification and Solid Oxide Fuel Cell System

    DEFF Research Database (Denmark)

    Bang-Møller, Christian

    . The work deals with the coupling of thermal biomass gasification and solid oxide fuel cells (SOFCs), and specific focus is kept on exploring the potential performance of hybrid CHP systems based on the novel two-stage gasification concept and SOFCs. The two-stage gasification concept is developed...

  14. Dicty_cDB: CHP110 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available CH (Link to library) CHP110 (Link to dictyBase) - - - Contig-U10711-1 | Contig-U13105-1 CHP1...10P (Link to Original site) CHP110F 130 CHP110Z 390 CHP110P 500 - - Show CHP110 Library CH (Link to library) Clone ID CHP1...11-1 | Contig-U13105-1 Original site URL http://dictycdb.biol.tsukuba.ac.jp/CSM/CH/CHP1-A/CHP1...10Q.Seq.d/ Representative seq. ID CHP110P (Link to Original site) Representative DNA sequence >CHP110 (CHP1...10Q) /CSM/CH/CHP1-A/CHP110Q.Seq.d/ TGTTGGCCTACTGGNACCTCCAACAAATAACAACCAACTTAGNATTTGTCAATTATATAT

  15. The role of combined heat and power (CHP) in energy and climate policy

    International Nuclear Information System (INIS)

    In the energy- and environment context CHP is said to be especially energy saving and climate preserving. This report shows that from the standpoint of energy economics as well as under technical aspects this judgement holds true only under special conditions. Depending on the technical parameters, the concrete circumstances of operation and the characteristics of the power plants and heating systems compared to CHP-plants the range of realistic energy savings turns out to be very large. Related overstimations are to a good extend caused by the traditional practice of granting the energetic advantage of CHP exclusively to the district heating. If this advantage is credited to heat and power as equal shares space heating with cogenerated power of 80% efficiency reveals to be very energy conserving. The uno actu utilization of cogenerated heat and power, for the same purpose could facilitate the expansion of CHP, since the problems related to the feeding of cogenerated power into the grid for general purposes would disappear. The second main issue of this report concerns the abatement of CO2-emissions with the aid of CHP. Fuelled with natural gas, CHP-plants are attractive instruments for climate policy. This is especially true if CHP is compared to old coal-based power plants and oil-fuelled old heating systems. In the FRG, however, hard coal, and not natural gas, will be the main fuel for future CHP, lowering its CO2-advantage considerably. On the other hand high efficient combi-power plants (gas turbine plus condensing turbine) and gas heating systems have to be included in the comparative analyse. Compared to these advanced systems the CO2-characteristics of CHP are inferior. Moreover, the specific CO2-advantage of natural gas is better used by such modern mono systems rather than CHP-plants. (orig.)

  16. CHP Integrated with Burners for Packaged Boilers

    Energy Technology Data Exchange (ETDEWEB)

    Castaldini, Carlo; Darby, Eric

    2013-09-30

    The objective of this project was to engineer, design, fabricate, and field demonstrate a Boiler Burner Energy System Technology (BBEST) that integrates a low-cost, clean burning, gas-fired simple-cycle (unrecuperated) 100 kWe (net) microturbine (SCMT) with a new ultra low-NOx gas-fired burner (ULNB) into one compact Combined Heat and Power (CHP) product that can be retrofit on new and existing industrial and commercial boilers in place of conventional burners. The Scope of Work for this project was segmented into two principal phases: (Phase I) Hardware development, assembly and pre-test and (Phase II) Field installation and demonstration testing. Phase I was divided into five technical tasks (Task 2 to 6). These tasks covered the engineering, design, fabrication, testing and optimization of each key component of the CHP system principally, ULNB, SCMT, assembly BBEST CHP package, and integrated controls. Phase I work culminated with the laboratory testing of the completed BBEST assembly prior to shipment for field installation and demonstration. Phase II consisted of two remaining technical tasks (Task 7 and 8), which focused on the installation, startup, and field verification tests at a pre-selected industrial plant to document performance and attainment of all project objectives. Technical direction and administration was under the management of CMCE, Inc. Altex Technologies Corporation lead the design, assembly and testing of the system. Field demonstration was supported by Leva Energy, the commercialization firm founded by executives at CMCE and Altex. Leva Energy has applied for patent protection on the BBEST process under the trade name of Power Burner and holds the license for the burner currently used in the product. The commercial term Power Burner is used throughout this report to refer to the BBEST technology proposed for this project. The project was co-funded by the California Energy Commission and the Southern California Gas Company (SCG), a

  17. Energy Analysis of a Fuel Cell System for Commercial Greenhouse Applications

    OpenAIRE

    Sardella, Marco

    2013-01-01

    Sustainable energy management becomes more important due to the ever more actual problems of environmental pollution and limited natural resources. The fuel cell technology is one of the most attractive solutions in this sense. During the past decades fuel cells have been investigated and demonstrated for several applications. One of the most attractive applications is using fuel cell system for stationary energy cogeneration (CHP), since they are capable of producing thermal energy and power...

  18. Economic advantages of applying model predictive control to distributed energy resources: The case of micro-CHP systems

    NARCIS (Netherlands)

    Houwing, M.; Negenborn, R.R.; De Schutter, B.

    2008-01-01

    The increasing presence of distributed energy resources, information and intelligence in the electricity infrastructure increases the possibilities for larger economic efficiency of power systems. This work shows the possible cost advantages of applying a model predictive control (MPC) strategy to r

  19. Review of CHP projections tp 2010

    Energy Technology Data Exchange (ETDEWEB)

    Choudhury, W.

    2003-07-01

    This report summarises the findings of a study examining market conditions for combined heat and power since 2000 and assessing the commercial position of cogeneration (CHP) in order to provide advice on likely distributed generation in relation to technology, location and commissioning timetables. Details are given of the modelling of the development of 'good quality' CHP by Cambridge Econometrics (CE), and the work carried out by ILEX updating the CE study. Modelling assumptions, market conditions for CHP since the CE study, the effect of market conditions on CE modelling assumptions, justified changes in assumptions, and evaluation of likely CHP capacity to 2010 are discussed.

  20. Modeling and optimization of a heat-pump-assisted high temperature proton exchange membrane fuel cell micro-combined-heat-and-power system for residential applications

    DEFF Research Database (Denmark)

    Arsalis, Alexandros; Kær, Søren Knudsen; Nielsen, Mads Pagh

    2015-01-01

    In this study a micro-combined-heat-and-power (micro-CHP) system is coupled to a vapor-compression heat pump to fulfill the residential needs for heating (space heating and water heating) and electricity in detached single-family households in Denmark. Such a combination is assumed to be attractive...... for application, since both fuel cell technology and electric heat pumps are found to be two of the most efficient technologies for generation/conversion of useful energy. The micro-CHP system is fueled with natural gas and includes a fuel cell stack, a fuel processor and other auxiliary components. The micro....... The variational loads are considered from full to quarter load, and the micro-CHP system is optimized in terms of operating thermophysical parameters for every different load. The results clearly indicate the capability of the proposed system to perform efficiently throughout all necessary load changes to fulfill...

  1. Design and simulation of a prototype of a small-scale solar CHP system based on evacuated flat-plate solar collectors and Organic Rankine Cycle

    International Nuclear Information System (INIS)

    Highlights: • A novel small scale solar power plant was designed and simulated. • The system is based on evacuated solar thermal collectors and an ORC system. • An average electric efficiency of 10% was found for the ORC. • The efficiency of solar collectors was found to be high in summer (>50%). • Pay-back periods lower than 5 years were estimated, in case of public funding. - Abstract: This paper presents a dynamic simulation model of a novel prototype of a 6 kWe solar power plant. The system is based on the coupling of innovative solar thermal collectors with a small Organic Rankine Cycle (ORC), simultaneously producing electric energy and low temperature heat. The novelty of the proposed system lies in the solar collector field, which is based on stationary evacuated flat-plate solar thermal collectors capable to achieve the operating temperatures typical of the concentrating solar thermal collectors. The solar field consists of about 73.5 m2 of flat-plate evacuated solar collectors, heating a diathermic oil up to a maximum temperature of 230 °C. A diathermic oil storage tank is employed in order to mitigate the fluctuations due to the variability of solar energy availability. The hot diathermic oil exiting from the tank passes through an auxiliary gas-fired burner which provides eventual additional thermal energy. The inlet temperature of the diathermic oil entering the ORC system varies as a function of the availability of solar energy, also determining an oscillating response of the ORC. The ORC was simulated in Engineering Equation Solver (EES), using zero-dimensional energy and mass balances. The ORC model was subsequently implemented in a more general TRNSYS model, including all the remaining components of the system. The model was used to evaluate the energy and economic performance of the solar CHP system under analysis, in different climatic conditions. The results show that the efficiency of the ORC does not significantly vary during the

  2. Exergy analysis and optimization of a biomass gasification, solid oxide fuel cell and micro gas turbine hybrid system

    DEFF Research Database (Denmark)

    Bang-Møller, Christian; Rokni, Masoud; Elmegaard, Brian

    2011-01-01

    A hybrid plant producing combined heat and power (CHP) from biomass by use of a two-stage gasification concept, solid oxide fuel cells (SOFC) and a micro gas turbine was considered for optimization. The hybrid plant represents a sustainable and efficient alternative to conventional decentralized...... CHP plants. A clean product gas was produced by the demonstrated two-stage gasifier, thus only simple gas conditioning was necessary prior to the SOFC stack. The plant was investigated by thermodynamic modeling combining zero-dimensional component models into complete system-level models. Energy...

  3. Modelling Danish local CHP on market conditions

    DEFF Research Database (Denmark)

    Ravn, Hans V.; Riisom, Jannik; Schaumburg-Müller, Camilla;

    2004-01-01

    the local heat demand as well as technical factors such as heat storage facilities and production unit characteristics. Based on an adaptive prognosis for electricity spot prices, bids for the spot market are made in accordance with the rules of the Nord Pool 24-hour cycle. The paper will discuss...... in the Western Danish system. As both the power produced by the local CHPs and the wind power are prioritised, the production of these types of power is occasionally sufficient to meet the total demand in the system, causing the market price to drop dramatically, sometimes even to zero-level. In line...... with the liberalisation process of the energy sectors of the EU countries, it is however anticipated that Danish local CHP are to begin operating on market conditions within the year 2005. This means that the income that the local CHPs previously gained from selling electricity at the feed-in tariff is replaced in part...

  4. 天然气CHP、CCHP系统在工业企业的应用%Application of Natural Gas CHP and CCHP Systems to Industrial Enterprises

    Institute of Scientific and Technical Information of China (English)

    王振兴; 乔艳丽

    2011-01-01

    介绍了天然气热电联供(CHP)系统、天然气冷热电联供(CCHP)系统在我国的发展现状,提出在工业企业应用天然气CHP、CCHP系统,改变采用一次能源直接供应热风、热水的现状,实现能源的梯级利用,提高能源利用效率.

  5. Omakotitalokokoluokan mikro-CHP-laitokset

    OpenAIRE

    Kyllönen, Matias

    2015-01-01

    Työ tehtiin Oulun yliopiston Oulun Eteläisen instituutin Tulevaisuuden tuotantoteknologiat (FMT) -tutkimusryhmälle. Työn aiheena on tulevaisuuden energiaratkaisu omakotitalokokoluokassa. Tavoitteena opinnäytetyössä on miettiä konsepti mikro-CHP-laitokselle, jossa höyrykone on lämpövoimakoneena pyörittämässä generaattoriin liitettyä akselia. Tavoitteena on tehdä mahdollisimman kompakti hyvin eristetty laitos tulevaisuuden omakotitalon energiatarpeen tyydyttämiseksi. Työn on tehty tiedonha...

  6. Mini-Central heating and Power Plant (CHP): the choice of the optimal structure and modes of operation

    Science.gov (United States)

    Gil'manshin, I. R.; Konahina, I. A.; Kashapov, N. F.; Fahreev, N. N.

    2014-12-01

    The paper provides an overview of the different types of organizations of mini-CHP, the results of a comparative evaluation of their performance in terms of the variable load. The recommendations to improve power facilities of the mini-CHP on the basis of system analysis methods and the technical and economic optimization are defined.

  7. The role of fuel cells and electrolysers in future efficient energy systems

    Energy Technology Data Exchange (ETDEWEB)

    Vang Hendriksen, P.; Pedersen, Allan S.; Linderoth, S. [Technical Univ. of Denmark. DTU Energy Conversion, Roskilde (Denmark); Vad Mathiesen, B. [Aalborg Univ.. Dept. of Development and Planning, Aalborg (Denmark)

    2012-11-15

    Fuel cells possess a number of other characteristics which make them relevant to many different applications in the future energy system. They are by nature modular and may thus be used at a wide variety of scales: from battery replacements (0.1-1 kW), through combined heat and power (CHP) for single houses (1-10 kW) and decentralised units (100 kW-5 MW), to large centralised power and CHP plants (100-500 MW). Fuel cells may also be operated in reverse mode, as electrolysers, to convert electrical energy to chemical energy. An example is the reduction of steam to hydrogen and CO{sub 2} to CO; using well-known catalytic routes the resulting gases can be further converted to a range of hydrocarbons which may be used as transport fuels, such as methanol, DME and even synthetic diesel. Several different types of fuel cells exist. They can be classified by the type of electrolyte used. All have their advantages and disadvantages, but none has to date matured to a level where fuel cells are in widespread commercial use or play a significant role in the energy system. Alkaline fuel cells have been used for space and military applications but are expensive and challenging to use in other applications. Phosphoric acid (PAFC), molten carbonate (MCFC) and alkaline (AFC) fuel cells have historically attracted a lot of R and D, but still face a number of challenges for commercial use. Low- and high-temperature PEM and solid oxide (SOFC) fuel cells are currently attracting the largest development efforts for CHP and transport applications. Domestic CHP units based on both PEMFCs and SOFCs have recently been launched by industrial suppliers as have larger units for distributed generation. Fuel cells and electrolysis cells are still to enter a wide spread use, but the technologies have great potential in a future more efficient and more sustainable energy system. (LN)

  8. Crystallization and preliminary crystallographic analysis of the human calcineurin homologous protein CHP2 bound to the cytoplasmic region of the Na+/H+ exchanger NHE1

    International Nuclear Information System (INIS)

    Crystallization of the human CHP2–NHE1 binding domain complex. Calcineurin homologous protein (CHP) is a Ca2+-binding protein that directly interacts with and regulates the activity of all plasma-membrane Na+/H+-exchanger (NHE) family members. In contrast to the ubiquitous isoform CHP1, CHP2 is highly expressed in cancer cells. To understand the regulatory mechanism of NHE1 by CHP2, the complex CHP2–NHE1 (amino acids 503–545) has been crystallized by the sitting-drop vapour-diffusion method using PEG 3350 as precipitant. The crystals diffract to 2.7 Å and belong to a tetragonal space group, with unit-cell parameters a = b = 49.96, c = 103.20 Å

  9. Energy System and Thermoeconomic Analysis of Combined Heat and Power High Temperature Proton Exchange Membrane Fuel Cell Systems for Light Commercial Buildings

    Energy Technology Data Exchange (ETDEWEB)

    Colella, Whitney G.; Pilli, Siva Prasad

    2015-06-01

    The United States (U.S.) Department of Energy (DOE)’s Pacific Northwest National Laboratory (PNNL) is spearheading a program with industry to deploy and independently monitor five kilowatt-electric (kWe) combined heat and power (CHP) fuel cell systems (FCSs) in light commercial buildings. This publication discusses results from PNNL’s research efforts to independently evaluate manufacturer-stated engineering, economic, and environmental performance of these CHP FCSs at installation sites. The analysis was done by developing parameters for economic comparison of CHP installations. Key thermodynamic terms are first defined, followed by an economic analysis using both a standard accounting approach and a management accounting approach. Key economic and environmental performance parameters are evaluated, including (1) the average per unit cost of the CHP FCSs per unit of power, (2) the average per unit cost of the CHP FCSs per unit of energy, (3) the change in greenhouse gas (GHG) and air pollution emissions with a switch from conventional power plants and furnaces to CHP FCSs; (4) the change in GHG mitigation costs from the switch; and (5) the change in human health costs related to air pollution. From the power perspective, the average per unit cost per unit of electrical power is estimated to span a range from $15–19,000/ kilowatt-electric (kWe) (depending on site-specific changes in installation, fuel, and other costs), while the average per unit cost of electrical and heat recovery power varies between $7,000 and $9,000/kW. From the energy perspective, the average per unit cost per unit of electrical energy ranges from $0.38 to $0.46/kilowatt-hour-electric (kWhe), while the average per unit cost per unit of electrical and heat recovery energy varies from $0.18 to $0.23/kWh. These values are calculated from engineering and economic performance data provided by the manufacturer (not independently measured data). The GHG emissions were estimated to decrease by

  10. Tumor associated antigen CHP2 promotes intraperitoneal metastasis of HEK293 cells in nude mice%肿瘤相关抗原CHP2促进HEK293细胞在裸鼠腹腔内的转移

    Institute of Scientific and Technical Information of China (English)

    钱晓萍; 孙秀媛; 李国栋; 张毓; 陈慰峰

    2009-01-01

    目的:研究肿瘤相关抗原CHP2对HEK293细胞在裸鼠腹腔内转移能力的影响,并初步探讨其可能的分子机制.方法:通过Boyden小室法检测CHP2转染细胞和对照细胞的体外转移能力.对BALB/c裸鼠进行腹腔接种,观察裸鼠体内的成瘤与组织浸润情况并进行HE染色.利用RT-PCR方法检测HEK293细胞中部分转移相关分子的基因表达水平.结果:CHP2增强HEK293细胞在体外穿过Matrigel胶的侵袭能力,同时显著加速HEK293细胞在裸鼠腹腔内的成瘤速度并促进肿瘤对腹腔主要脏器的浸润.CHP2上调转移相关分子骨桥蛋白(osteopon-tin,OPN)在HEK293细胞中的表达,但对基质金属蛋白酶MMP2的表达没有明显影响.结论:CHP2显著增强HEK293细胞在体外及裸鼠腹腔内的转移能力,OPN表达上调可能参与CHP2对HEK293细胞的转移促进作用.

  11. Reactive power control with CHP plants - A demonstration

    DEFF Research Database (Denmark)

    Nyeng, Preben; Østergaard, Jacob; Andersen, Claus A.;

    2010-01-01

    In this project the potential for ancillary services provision by distributed energy resources is investigated. Specifically, the provision of reactive power control by combined heat and power plants is examined, and the application of the new standard for DER communication systems, IEC 61850...... lines to underground cables has changed the reactive power balance, and third, the TSO has introduced restrictions in the allowed exchange of reactive power between the transmission system and distribution grids (known as the Mvar-arrangement). The demonstration includes a CHP plant with an electric...... power rating of 7.3 MW on two synchronous generators. A closed-loop control is implemented, that remote controls the CHP plant to achieve a certain reactive power flow in a near-by substation. The solution communicates with the grid operator’s existing SCADA system to obtain measurements from...

  12. Risk analysis for CHP decision making within the conditions of an open electricity market

    International Nuclear Information System (INIS)

    Decision making under uncertainty is a difficult task in most areas. Investment decisions for combined heat and power production (CHP) are certainly one of the areas where it is difficult to find an optimal solution since the payback period is several years and parameters change due to different perturbing factors of economic and mostly political nature. CHP is one of the most effective measures for saving primary energy and reduction of greenhouse gas emissions. The implementation of EU directives on the promotion of cogeneration based on useful heat demand in the internal energy market will accelerate CHP installation. The expected number of small CHP installations will be very high in the near future. A quick, reliable and simple tool for economic evaluation of small CHP systems is required. Since evaluation is normally made by sophisticated economic computer models which are rather expensive, a simple point estimate economic model was developed which was later upgraded by risk methodology to give more informative results for better decision making. This paper presents a reliable computer model entitled ''Computer program for economic evaluation analysis of CHP'' as a tool for analysis and economic evaluation of small CHP systems with the aim of helping the decision maker. The paper describes two methods for calculation of the sensitivity of the economic results to changes of input parameters and the uncertainty of the results: the classic/static method and the risk method. The computer program uses risk methodology by applying rate at RISK software on an existing conventional economic model. The use of risk methodology for economic evaluation can improve decisions by incorporating all possible information (knowledge), which cannot be done in the conventional economic model due to its limitations. The methodology was tested on the case of a CHP used in a smaller hospital. (author)

  13. Risk analysis for CHP decision making within the conditions of an open electricity market

    International Nuclear Information System (INIS)

    Decision making under uncertainty is a difficult task in most areas. Investment decisions for combined heat and power production (CHP) are certainly one of the areas where it is difficult to find an optimal solution since the payback period is several years and parameters change due to different perturbing factors of economic and mostly political nature. CHP is one of the most effective measures for saving primary energy and reduction of greenhouse gas emissions. The implementation of EU directives on the promotion of cogeneration based on useful heat demand in the internal energy market will accelerate CHP installation. The expected number of small CHP installations will be very high in the near future. A quick, reliable and simple tool for economic evaluation of small CHP systems is required. Since evaluation is normally made by sophisticated economic computer models which are rather expensive, a simple point estimate economic model was developed which was later upgraded by risk methodology to give more informative results for better decision making. This paper presents a reliable computer model entitled 'Computer program for economic evaluation analysis of CHP' as a tool for analysis and economic evaluation of small CHP systems with the aim of helping the decision maker. The paper describes two methods for calculation of the sensitivity of the economic results to changes of input parameters and the uncertainty of the results: the classic/static method and the risk method. The computer program uses risk methodology by applying RISK software on an existing conventional economic model. The use of risk methodology for economic evaluation can improve decisions by incorporating all possible information (knowledge), which cannot be done in the conventional economic model due to its limitations. The methodology was tested on the case of a CHP used in a smaller hospital

  14. Application of an improved operational strategy for a high temperature-proton exchange membrane fuel cell-based micro-combined heat and power system for Danish single-family households

    DEFF Research Database (Denmark)

    Arsalis, Alexandros; Nielsen, Mads Pagh; Kær, Søren Knudsen

    2013-01-01

    characteristics. Based on these findings, an improved operational strategy is formulated and applied in an attempt to minimize the shortcomings of conventional strategies. System parameters, such as electrical and thermal efficiencies, heat dumping, and import/export of electricity, are analyzed. The applied load...... be justified as compared to other micro-CHP system technologies. The most important findings of this research study indicate that in comparison to non-fuel cell-based micro-CHP systems, such as Stirling Engine-based systems, the proposed system has significantly higher efficiencies. Moreover, the lower heat...

  15. Micro CHP: implications for energy companies

    Energy Technology Data Exchange (ETDEWEB)

    Harrison, Jeremy [EA Technology (United Kingdom); Kolin, Simon; Hestevik, Svein [Sigma Elektroteknisk A/S (Norway)

    2000-08-01

    This article explains how micro combined heat and power (CHP) technology may help UK energy businesses to maintain their customer base in the current climate of liberalisation and competition in the energy market The need for energy companies to adopt new technologies and adapt to changes in the current aggressive environment, the impact of privatisation, and the switching of energy suppliers by customers are discussed. Three potential routes to success for energy companies are identified, namely, price reductions, branding and affinity marketing, and added value services. Details are given of the implementation of schemes to encourage energy efficiency, the impact of the emissions targets set at Kyoto, the advantages of micro CHP generation, business opportunities for CHP, business threats from existing energy companies and others entering the field, and the commercial viability of micro CHP.

  16. Integrated Solid Oxide Fuel Cell Power System Characteristics Prediction

    Directory of Open Access Journals (Sweden)

    Marian GAICEANU

    2009-07-01

    Full Text Available The main objective of this paper is to deduce the specific characteristics of the CHP 100kWe Solid Oxide Fuel Cell (SOFC Power System from the steady state experimental data. From the experimental data, the authors have been developed and validated the steady state mathematical model. From the control room the steady state experimental data of the SOFC power conditioning are available and using the developed steady state mathematical model, the authors have been obtained the characteristic curves of the system performed by Siemens-Westinghouse Power Corporation. As a methodology the backward and forward power flow analysis has been employed. The backward power flow makes possible to obtain the SOFC power system operating point at different load levels, resulting as the load characteristic. By knowing the fuel cell output characteristic, the forward power flow analysis is used to predict the power system efficiency in different operating points, to choose the adequate control decision in order to obtain the high efficiency operation of the SOFC power system at different load levels. The CHP 100kWe power system is located at Gas Turbine Technologies Company (a Siemens Subsidiary, TurboCare brand in Turin, Italy. The work was carried out through the Energia da Ossidi Solidi (EOS Project. The SOFC stack delivers constant power permanently in order to supply the electric and thermal power both to the TurboCare Company and to the national grid.

  17. CHP调节NHE1活性影响细胞生长和死亡%CHP Regulated NHE1 Activity Affects Cell Growth and Death

    Institute of Scientific and Technical Information of China (English)

    李庆华; 庞天翔; 韩忠朝

    2005-01-01

    钠氢离子交换蛋白(NHE)定位于细胞膜,它的重要功能是调节细胞内pH值.钙调磷酸酶B同源蛋白(CHP)是NHE必要的活性调节亚单位.研究了NHE1结合CHP与否对细胞生长和死亡的影响.结果显示,CHP结合于NHE1细胞质调节区域之中靠近细胞膜部位,二者以疏水键结合而形成蛋白Ⅳ级结构.在细胞内pH5.4的非生理条件下,表达没有CHP结合能力的突变体NHE1-4R细胞只有表达野生型NHE细胞7.6%的最大摄取钠活性;在细胞内pH7.2的生理条件下,这个比例降至1.2%的摄取钠活性.与野生型NHE1比较,有血清时表达突变体NHE1-4R的细胞生长速度减慢;在血清饥饿时这些细胞因自身的胞浆酸性化而死亡数增加.实验结果证明,CHP是NHE1生理活性的必要调节因子,它能影响细胞生长和死亡.

  18. Nuclear-localized Calcineurin Homologous Protein CHP1 Interacts with Upstream Binding Factor and Inhibits Ribosomal RNA Synthesis*

    OpenAIRE

    Jiménez-Vidal, Maite; Srivastava, Jyoti; Putney, Luanna K; Barber, Diane L.

    2010-01-01

    Calcineurin homologous protein 1 (CHP1) is a widely expressed, 22-kDa myristoylated EF-hand Ca2+-binding protein that shares a high degree of similarity with the regulatory B subunit of calcineurin (65%) and with calmodulin (59%). CHP1 localizes to the plasma membrane, the Golgi apparatus, and the nucleus and functions to regulate trafficking of early secretory vesicles, activation of T cells, and expression and transport of the Na-H exchanger NHE1. Although CHP1 contains nuclear export signa...

  19. Comparison of district heating CHP and distributed generation CHP with energy, environmental and economic criteria for Northern Italy

    International Nuclear Information System (INIS)

    Highlights: • District heating CHP and distributed generation CHP are compared. • Energy, environmental and economic aspects are considered. • Analysed prime movers: internal combustion engines, microturbines, fuel cells. • Two scenario are discussed: maximum energy saving and maximum present value saving. • The trend of all the savings versus the CHP-size is also analysed. - Abstract: District heating CHP (combined heat and power) and distributed generation CHP have been compared in this paper on the basis of energy, environmental and economic criteria, and a deviation index has been proposed to establish, in aggregate form, what the improvement margins are for a given design choice. Three technologies that are suitable for both district heating and distributed generation have been chosen: a mature market technology, internal combustion engines, and recent entry market technologies, that is, microturbines, and fuel cells. The calculations have been based on the real heating load curve of a town in Northern Italy at the current market conditions: power and fuel prices, tax exemptions relative to cogeneration, white certificates, etc. Two scenarios have been considered: maximum energy saving and maximum present value saving. In the first scenario, district heating obtained better energy and CO2 savings than distributed generation, but critical values have been observed for local nitrogen oxides (NOx) and particulate matter emissions, when internal combustion engines are adopted. In the second scenario, all the options offer positive energy, environmental and economic savings, and the payback times are significantly reduced compared to the previous scenario. The district heating options show the best present value savings and payback times, while distributed generation is only economically viable when internal combustion engines are adopted. Microturbines leads to the best NOx savings. Finally, the comparison with an alternative separate production of heat

  20. Preclinical Safety Pharmacology Study of a Novel Protein-Based Cancer Vaccine CHP-NY-ESO-1

    OpenAIRE

    Harada, Naozumi; Hoshiai, Kiyotaka; Takahashi, Yoshiyasu; Sakaguchi, Yasue; Kuno, Takayoshi; Hishida, Tadashi; Shiku, Hiroshi

    2008-01-01

    CHP-NY-ESO-1 is a novel therapeutic cancer vaccine consisting of a recombinantprotein of cancer antigen NY-ESO-1 and a polysaccharide-based delivery system,cholesteryl pullulan. A pilot clinical study of CHP-NY-ESO-1 in cancer patients waspreviously conducted, and the adverse events related to this drug were observed to belimited to skin reactions at injection sites. To further establish the safety ofCHP-NY-ESO-1, we studied the effects of its subcutaneous injection on vital functionssuch as ...

  1. Small-Scale CHP Potential in Latvia and Estonia

    OpenAIRE

    Volkova, A.; Latosev, E; Siirde, A

    2009-01-01

    In the research the small-scale CHP potential of Latvia and Estonia has been defined. Factors, which influence the CHP development, were analyzed in this paper, including political, geographic, climatological, legislative and technological factors. For the small-scale CHP potential assessment the three alternatives were chosen. The first alternative is the case, when only the hot water is taken into account. In this case the CHP can work with full load during the whole year because the heat l...

  2. The Added Economic and Environmental Value of Solar Thermal Systems in Microgrids with Combined Heat and Power

    OpenAIRE

    Marnay, Chris

    2010-01-01

    The addition of solar thermal and heat storage systems can improve the economic, as well as environmental attraction of micro-generation systems, e.g. fuel cells with or without combined heat and power (CHP) and contribute to enhanced CO2 reduction. However, the interactions between solar thermal collection and storage systems and CHP systems can be complex, depending on the tariff structure, load profile, etc. In order to examine the impact of solar thermal and heat storage on CO2 emissions ...

  3. Operational Strategies for a Portfolio of Wind Farms and CHP Plants in a Two-Price Balancing Market

    DEFF Research Database (Denmark)

    Hellmers, Anna; Zugno, Marco; Skajaa, Anders;

    2015-01-01

    . We investigate two different operational strategies, which differ in whether the CHP plant and the wind farm are operated jointly or independently, and we evaluate their economic performance on a real case study based on a CHP-wind system located in the western part of Denmark. We present......In this paper we explore the portfolio effect of a system consisting of a Combined Heat and Power (CHP) plant and a wind farm. The goal is to increase the overall profit of the portfolio by reducing imbalances, and consequently their implicit penalty in a two-price balancing market for electricity...... a comprehensive mathematical model for describing the different heat and power production units of the CHP plant, and suggest different ways of determining its operation in a setup with two trading floors: a day-ahead market and a balancing market. We build a simulation framework that runs in a rolling...

  4. CHP unit and local heating system using sewage gas - optimised sewage gas use and power generation; BHKW mit Waermeverbund der IVF HARTMANN AG mit Klaergas aus der ARA Roeti/SH; optimierte Klaergasnutzung und Verstromung durch Kooperation von ARA und Industrie

    Energy Technology Data Exchange (ETDEWEB)

    Roeck, P.M.

    2001-07-01

    This report for the Swiss Federal Office of Energy (SFOE) describes a combined heat and power (CHP) installation in Neuhausen am Rheinfall, Switzerland. This refurbishment project, which uses sewage gas produced in a local sewage treatment plant to supply a 215 kW CHP unit running in a local factory is described. Heat produced by the unit is sold back to the sewage treatment plant to cover its demands. Electricity production is used in-house in the industrial facilities. The report reviews the origins and development of the project and gives figures on sewage gas, heat and electricity production. Initial experience gained in this co-operative project is discussed. Also, the measurement and monitoring system, which forms the basis of result-checking and billing of energy services between the sewage plant operator and the industrial company, is described.

  5. Changes of the thermodynamic parameters in failure conditions of the micro-CHP cycle

    Directory of Open Access Journals (Sweden)

    Matysko Robert

    2014-03-01

    Full Text Available The paper presents the calculations for the failure conditions of the ORC (organic Rankine cycle cycle in the electrical power system. It analyses the possible reasons of breakdown, such as the electrical power loss or the automatic safety valve failure. The micro-CHP (combined heat and power system should have maintenance-free configuration, which means that the user does not have to be acquainted with all the details of the ORC system operation. However, the system should always be equipped with the safety control systems allowing for the immediate turn off of the ORC cycle in case of any failure. In case of emergency, the control system should take over the safety tasks and protect the micro-CHP system from damaging. Although, the control systems are able to respond quickly to the CHP system equipped with the inertial systems, the negative effects of failure are unavoidable and always remain for some time. Moreover, the paper presents the results of calculations determining the inertia for the micro-CHP system of the circulating ORC pump, heat removal pump (cooling condenser and the heat supply pump in failure conditions.

  6. Changes of the thermodynamic parameters in failure conditions of the micro-CHP cycle

    Science.gov (United States)

    Matysko, Robert; Mikielewicz, Jarosław; Ihnatowicz, Eugeniusz

    2014-03-01

    The paper presents the calculations for the failure conditions of the ORC (organic Rankine cycle) cycle in the electrical power system. It analyses the possible reasons of breakdown, such as the electrical power loss or the automatic safety valve failure. The micro-CHP (combined heat and power) system should have maintenance-free configuration, which means that the user does not have to be acquainted with all the details of the ORC system operation. However, the system should always be equipped with the safety control systems allowing for the immediate turn off of the ORC cycle in case of any failure. In case of emergency, the control system should take over the safety tasks and protect the micro-CHP system from damaging. Although, the control systems are able to respond quickly to the CHP system equipped with the inertial systems, the negative effects of failure are unavoidable and always remain for some time. Moreover, the paper presents the results of calculations determining the inertia for the micro-CHP system of the circulating ORC pump, heat removal pump (cooling condenser) and the heat supply pump in failure conditions.

  7. Network Capacity Assessment of CHP-based Distributed Generation on Urban Energy Distribution Networks

    Science.gov (United States)

    Zhang, Xianjun

    The combined heat and power (CHP)-based distributed generation (DG) or dis-tributed energy resources (DERs) are mature options available in the present energy market, considered to be an effective solution to promote energy efficiency. In the urban environment, the electricity, water and natural gas distribution networks are becoming increasingly interconnected with the growing penetration of the CHP-based DG. Subsequently, this emerging interdependence leads to new topics meriting serious consideration: how much of the CHP-based DG can be accommodated and where to locate these DERs, and given preexisting constraints, how to quantify the mutual impacts on operation performances between these urban energy distribution networks and the CHP-based DG. The early research work was conducted to investigate the feasibility and design methods for one residential microgrid system based on existing electricity, water and gas infrastructures of a residential community, mainly focusing on the economic planning. However, this proposed design method cannot determine the optimal DG sizing and siting for a larger test bed with the given information of energy infrastructures. In this context, a more systematic as well as generalized approach should be developed to solve these problems. In the later study, the model architecture that integrates urban electricity, water and gas distribution networks, and the CHP-based DG system was developed. The proposed approach addressed the challenge of identifying the optimal sizing and siting of the CHP-based DG on these urban energy networks and the mutual impacts on operation performances were also quantified. For this study, the overall objective is to maximize the electrical output and recovered thermal output of the CHP-based DG units. The electricity, gas, and water system models were developed individually and coupled by the developed CHP-based DG system model. The resultant integrated system model is used to constrain the DG's electrical

  8. Characterization of ultrafine and fine particles from CHP Plants

    Energy Technology Data Exchange (ETDEWEB)

    2009-08-15

    Samples of particles collected at CHP plants in the project 'Survey of emissions from CHP Plants' have been analysed in this project to give information on the morphology and chemical composition of individual particle size classes. The objective of this project was to characterize ultrafine and fine particles emitted to the atmosphere from Danish CHP plants. Nine CHP plants were selected in the Emission Survey Project as being representative for the different types of CHP plants operating in Denmark: 1) Three Waste-to Energy (WTE) plants. 2) Three biomass fired (BM) plants (two straw fired, one wood/saw dust fired). 3) Two gas fired (GF) plants (one natural gas, one landfill gas fired). 4) One gasoil (GO) fired plant. At the WTE and BM plants, various types of emission control systems implemented. The results from these plants represent the composition and size distribution of combustion particles that are emitted from the plants emission control systems. The measured emissions of particles from the waste-to-energy plants WTE1-3 are generally very low. The number and mass concentrations of ultrafine particles (PM{sub 0.1}) were particularly low in the flue gas from WTE2 and WTE3, where bag filters are used for the reduction of particle emissions. The EDX analysis of particles from the WTE plants indicates that the PM{sub 0.1} that penetrates the ECS at WTE can contain high fractions of metals such as Fe, Mn and Cu. The SEM analysis of particles from WTE1-3 showed that the particles were generally porous and irregular in shape. The concentrations of particles in the flue gas from the biomass plants were generally higher than found for the WTE plants. The time series results showed that periodical, high concentration peaks of PM emissions occur from BM1 and BM2. The chemical composition of the particles emitted from the three biomass plants is generally dominated by C, O and S, and to some extend also Fe and Si. A high amount of Cu was found in selected

  9. Nanogel antigenic protein-delivery system for adjuvant-free intranasal vaccines.

    Science.gov (United States)

    Nochi, Tomonori; Yuki, Yoshikazu; Takahashi, Haruko; Sawada, Shin-ichi; Mejima, Mio; Kohda, Tomoko; Harada, Norihiro; Kong, Il Gyu; Sato, Ayuko; Kataoka, Nobuhiro; Tokuhara, Daisuke; Kurokawa, Shiho; Takahashi, Yuko; Tsukada, Hideo; Kozaki, Shunji; Akiyoshi, Kazunari; Kiyono, Hiroshi

    2010-07-01

    Nanotechnology is an innovative method of freely controlling nanometre-sized materials. Recent outbreaks of mucosal infectious diseases have increased the demands for development of mucosal vaccines because they induce both systemic and mucosal antigen-specific immune responses. Here we developed an intranasal vaccine-delivery system with a nanometre-sized hydrogel ('nanogel') consisting of a cationic type of cholesteryl-group-bearing pullulan (cCHP). A non-toxic subunit fragment of Clostridium botulinum type-A neurotoxin BoHc/A administered intranasally with cCHP nanogel (cCHP-BoHc/A) continuously adhered to the nasal epithelium and was effectively taken up by mucosal dendritic cells after its release from the cCHP nanogel. Vigorous botulinum-neurotoxin-A-neutralizing serum IgG and secretory IgA antibody responses were induced without co-administration of mucosal adjuvant. Importantly, intranasally administered cCHP-BoHc/A did not accumulate in the olfactory bulbs or brain. Moreover, intranasally immunized tetanus toxoid with cCHP nanogel induced strong tetanus-toxoid-specific systemic and mucosal immune responses. These results indicate that cCHP nanogel can be used as a universal protein-based antigen-delivery vehicle for adjuvant-free intranasal vaccination. PMID:20562880

  10. A price mechanism for supply demand matching in local grid of households with micro-CHP

    Science.gov (United States)

    Larsen, G. K. H.; van Foreest, N. D.; Scherpen, J. M. A.

    2012-10-01

    This paper describes a dynamic price mechanism to coordinate eletric power generation from micro Combined Heat and Power (micro-CHP) systems in a network of households. It is assumed that the households are prosumers, i.e. both producers and consumers of electricity. The control is done on household level in a completely distributed manner. Avoiding a centralized controller both eases computation complexity and preserves communication structure in the network. Local information is used to decide to turn on or off the micro-CHP, but through price signals between the prosumers the network as a whole operates in a cooperative way.

  11. Dicty_cDB: CHP195 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available CH (Link to library) CHP195 (Link to dictyBase) - - - Contig-U11819-1 - (Link to Or...iginal site) CHP195F 138 - - - - - - Show CHP195 Library CH (Link to library) Clone ID CHP195 (Link to dicty...Base) Atlas ID - NBRP ID - dictyBase ID - Link to Contig Contig-U11819-1 Original site URL http://dictycdb.b...qilkvstnk**IKNYYVNRVYEIIIIINICTYKKK--- Translated Amino Acid sequence (All Frames) Frame A: tvgllvfsnt*gink*...iin*kllck*sl*nnnynkymyi*kk--- Frame B: llaywffqilkvstnk**IKNYYVNRVYEIIIIINICTYKKK--- Frame C: cwptgffkylryqq

  12. Gasification for power, CHP and polygeneration Biomass Gasification for Combined Heat Power (CHP) Applications: the GAMECO Project

    OpenAIRE

    Authier, O; Khalfi, Az-Eddine; Sanchez, L.; Aleman, Y; Delebarre, A; Mauviel, G; Dufour, A; Rogaume, Y; Poirier, J.; Kerhoas, J

    2014-01-01

    International audience Air-blown fluidised bed biomass gasification is a well adapted technology for Combined Heat Power (CHP) applications with syngas valorisation in a gas engine. However, it is not mature yet. Despite promising prototypes, CHP gasification needs further improvements to become the reference technology in the medium-size CHP market. This is the purpose of the GAMECO project, which aims at improving an existing technology by optimising its operation, increasing its feedsto...

  13. Modelling of a CHP SOFC system fed with biogas from anaerobic digestion of municipal waste integrated with solar collectors and storage unit

    OpenAIRE

    Domenico Borello; Sara Evangelisti; Eileen Tortora

    2013-01-01

    The paradigm of the sustainable energy community is recognized as the future energy approach due to its economical, technical and environmental benefits. Future systems should integrate renewable energy systems applying a “community-scale” approach to maximize energy performances, while minimizing environmental impacts. Efforts have to be directed toward the promotion of integrated technical systems needed to expand the use of renewable energy resources, to build sustainable local and nationa...

  14. CHP expansion strategy in North Rhine-Westphalia. A blueprint for other regions; KWK-Ausbaustrategie in NRW. Eine Blaupause fuer andere Regionen

    Energy Technology Data Exchange (ETDEWEB)

    Holzapfel, Dominik [EnergieAgentur.NRW, Duesseldorf (Germany); Schneider, Sabine [EnergieAgentur.NRW, Wuppertal (Germany)

    2015-10-01

    The North Rhine-Westphalian state government intends to increase the share of combined heat and power (CHP) generation to at least 25 % by 2020. Since 2013, the campaign ''CHP.NRW - Power Meets Heat'' (''KWK.NRW - Strom trifft Waerme'') of the EnergyAgency.NRW, is has been running on behalf of the NRW Climate Protection Ministry, to publicise this technology and to promote its expansion. The campaign accompanies the State Government's CHP Stimulus Programme. The EnergyAgency.NRW has organised companies and research institutions, associations and interest groups under the umbrella of ''CHP.NRW - Power Meets Heat'', aiming at co-ordinated and intensified activities in the field of combined heat and power generation. The target of the initial-project ''roadmap/CHP.NRW'' of the ''Virtual Institute / CHP.NRW'' is to develop a guideline for the application and optimisation of CHP-systems.

  15. Micro Cooling, Heating, and Power (Micro-CHP) and Bio-Fuel Center, Mississippi State University

    Energy Technology Data Exchange (ETDEWEB)

    Louay Chamra

    2008-09-26

    Initially, most micro-CHP systems will likely be designed as constant-power output or base-load systems. This implies that at some point the power requirement will not be met, or that the requirement will be exceeded. Realistically, both cases will occur within a 24-hour period. For example, in the United States, the base electrical load for the average home is approximately 2 kW while the peak electrical demand is slightly over 4 kW. If a 3 kWe micro- CHP system were installed in this situation, part of the time more energy will be provided than could be used and for a portion of the time more energy will be required than could be provided. Jalalzadeh-Azar [6] investigated this situation and presented a comparison of electrical- and thermal-load-following CHP systems. In his investigation he included in a parametric analysis addressing the influence of the subsystem efficiencies on the total primary energy consumption as well as an economic analysis of these systems. He found that an increase in the efficiencies of the on-site power generation and electrical equipment reduced the total monthly import of electricity. A methodology for calculating performance characteristics of different micro-CHP system components will be introduced in this article. Thermodynamic cycles are used to model each individual prime mover. The prime movers modeled in this article are a spark-ignition internal combustion engine (Otto cycle) and a diesel engine (Diesel cycle). Calculations for heat exchanger, absorption chiller, and boiler modeling are also presented. The individual component models are then linked together to calculate total system performance values. Performance characteristics that will be observed for each system include maximum fuel flow rate, total monthly fuel consumption, and system energy (electrical, thermal, and total) efficiencies. Also, whether or not both the required electrical and thermal loads can sufficiently be accounted for within the system

  16. Changes of the thermodynamic parameters in failure conditions of the micro-CHP cycle

    OpenAIRE

    Matysko Robert; Mikielewicz Jarosław; Ihnatowicz Eugeniusz

    2014-01-01

    The paper presents the calculations for the failure conditions of the ORC (organic Rankine cycle) cycle in the electrical power system. It analyses the possible reasons of breakdown, such as the electrical power loss or the automatic safety valve failure. The micro-CHP (combined heat and power) system should have maintenance-free configuration, which means that the user does not have to be acquainted with all the details of the ORC system operation. However, the system should always be equipp...

  17. Trnsys simulation results of an existing monitored small scale CHCP system and mathematical model adaptations of the air-cooled ammonia chiller and CHP prototypes

    OpenAIRE

    Mendes, J. Farinha; Coelho, Ricardo; Cardoso, João P.; Costa, João P.; Fernández, David; Silva, António; Morgado, Miguel; Adão, Pedro

    2010-01-01

    This work is a TRNSYS simulation of solar thermal system working together with an existing small sized CHCP (Combinet Heat Cooling and Power) demonstration project, included in the workpackage 5 (simulation) of the PolySMART project. The first objective of this work is to fine tune simulation parameters of the simulation Units (or Types), based on monitoring data collected during the first semester of 2010. The second objective is to further develop the mathematical models of type 107 (Hot Wa...

  18. Biomass combustion gas turbine CHP

    Energy Technology Data Exchange (ETDEWEB)

    Pritchard, D.

    2002-07-01

    This report summarises the results of a project to develop a small scale biomass combustor generating system using a biomass combustor and a micro-gas turbine indirectly fired via a high temperature heat exchanger. Details are given of the specification of commercially available micro-turbines, the manufacture of a biomass converter, the development of a mathematical model to predict the compatibility of the combustor and the heat exchanger with various compressors and turbines, and the utilisation of waste heat for the turbine exhaust.

  19. Biomass CHP plant Guessing: reliable solution for fossil free municipality

    International Nuclear Information System (INIS)

    The start up of the biomass gasification CHP plant in 2002 marked the last step of the small Austrian town of Guessing towards the supply with 100 % biomass based renewable energy. Furthermore a sustainable process of regional development has been set into force, which turned this former poor region into a prospering European centre of renewable energy. Reaching an electric efficiency of 25 % and a total efficiency of 80 %, the process of steam blown gasification and gas utilisation in an engine enables economic operation even in small plants. For more than 11,000 operating hours the system could prove its reliability. Due to the favourable characteristics of the product gas research projects beyond electricity production were already started. (authors)

  20. Sewage Sludge Gasification for CHP Applications

    Energy Technology Data Exchange (ETDEWEB)

    McCahey, S.; Huang, Y.; McMullan, J.T.

    2003-07-01

    Many routes previously available for sewage sludge disposal within the European Union are now prohibited or constrained by environmental legislation. Meanwhile, sewage sludge production increases annually as more rigorous treatment processes are used. This paper introduces an ongoing project, supported by the European Commission FP5 Programme, which seeks to examine the key technical environmental and economic issues relating to the gasification of sewage sludge for utilisation in CHP applications and ultimately to establish the commercial viability of the process. Sewage sludge treatment data has been collected by country and region and a database compiled. Laboratory and pilot plant scale gasification trials are underway and two small engines and a generator have been installed and commissioned. This paper discusses the concurrent development of ECLIPSE process simulation models for the three selected gasification processes, namely fluidised bed, spouted bed and fixed bed. These models have been validated and are being used to predict the behaviour of appropriately sized commercial scale plant, enabling informed decisions regarding technical suitability. The next step in this project is to determine capital costs and economic performance. Process routes will be identified that offer the most cost effective routes to reducing environmental burdens by using sewage sludge in CHP applications. (author)

  1. Energy-optimisation of biogas-fuelled CHP units; Energetische Optimierung von Biogas-BHKW's

    Energy Technology Data Exchange (ETDEWEB)

    Soltic, P.; Edenhauser, D.; Winkler, A.

    2008-07-15

    This illustrated final report for the Swiss Federal office of Energy (SFOE) reports on the energy-related optimisation of combined heat and power (CHP) units that are fuelled with non-processed biogas. Ways of increasing the efficiency of these units as far as the production of electricity is concerned are examined and commented on. Also, ways of using the heat generated by the CHP units to produce electricity using other, exergetic means are also described. Systems such as Stirling engines and existing and new thermo-electrical elements are discussed. The economic viability of the systems is also discussed.

  2. Modeling and optimization of a heat-pump-assisted high temperature proton exchange membrane fuel cell micro-combined-heat-and-power system for residential applications

    International Nuclear Information System (INIS)

    Highlights: • We model a heat pump-assisted PEMFC micro-CHP system for single-family households. • We optimize the system net electrical efficiency at a range of varying loads. • The proposed system performs at an average net electrical efficiency of 0.38. • The proposed system performs at an average total system efficiency of 0.815. • Cost analysis shows the potential of the proposed system for different unit costs. - Abstract: In this study a micro-combined-heat-and-power (micro-CHP) system is coupled to a vapor-compression heat pump to fulfill the residential needs for heating (space heating and water heating) and electricity in detached single-family households in Denmark. Such a combination is assumed to be attractive for application, since both fuel cell technology and electric heat pumps are found to be two of the most efficient technologies for generation/conversion of useful energy. The micro-CHP system is fueled with natural gas and includes a fuel cell stack, a fuel processor and other auxiliary components. The micro-CHP system assumes heat-led operation, to avoid dumping of heat and the use of complicated thermal energy storage. The overall system is grid-interconnected to allow importing and exporting of electricity as necessary. In this study emphasis is given on the operational characterization of the system. The variational loads are considered from full to quarter load, and the micro-CHP system is optimized in terms of operating thermophysical parameters for every different load. The results clearly indicate the capability of the proposed system to perform efficiently throughout all necessary load changes to fulfill the residential load profile. The average net electrical efficiency and average total system efficiency are 0.380 and 0.815, respectively. However cost analysis shows that certain synergies are necessary to allow the proposed system to make an entry to the energy market as a possible candidate to replace heat pump

  3. The Impact of Modified EU ETS Allocation Principles on the Economics of CHP-based District Heating Networks

    OpenAIRE

    Westner, Günther; Madlener, Reinhard

    2011-01-01

    The economics of large-scale combined heat and power (CHP) generation for district heating (DH) applications are strongly affected by the costs and allocation mechanism of CO2 emission allowances. In the next period of the European emission trading system (EU ETS), from 2013 onwards, the allocation rules for CHP generation will be modified according to the principles announced in EU Directive 2009/29/EC. By means of a discounted cash-flow model we first show that the implementation of the mod...

  4. Development of a Wood Powder Fuelled 35 kW Stirling CHP Unit

    DEFF Research Database (Denmark)

    Pålsson, M.; Carlsen, Henrik

    2003-01-01

    For biomass fuelled CHP in sizes below 100 kW, Stirling engines are the only feasible alternative today. Using wood powder as fuel, the Stirling engine can be heated directly by the flame like when using a gaseous or liquid fuel burner. However, the combustion chamber will have to be much larger...... due to the slow burning of the fuel. To avoid sintering of ash the flame temperature in a biomass burner has to be quite low. The flame temperature can be lowered by using a high excess air rate; however this will lower system efficiency and needs a large air preheater. By using combustion gas...... recirculation (CGR) a smaller air preheater can be used, while system efficiency will increase compared with using excess air for flame cooling. In a three-year project, a wood powder fuelled Stirling engine CHP unit will be developed and run in field test. The project will use the double-acting four...

  5. Putney Basketville Site Biomass CHP Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Hunsberger, Randolph [National Renewable Energy Lab. (NREL), Golden, CO (United States); Mosey, Gail [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2013-10-01

    The U.S. Environmental Protection Agency (EPA) Office of Solid Waste and Emergency Response Center for Program Analysis developed the RE-Powering America's Land initiative to reuse contaminated sites for renewable energy generation when aligned with the community's vision for the site. The Putney, Vermont, Basketville site, formerly the location of a basket-making facility and a paper mill andwoolen mill, was selected for a feasibility study under the program. Biomass was chosen as the renewable energy resource based on abundant woody-biomass resources available in the area. Biomass combined heat and power (CHP) was selected as the technology due to nearby loads, including Putney Paper and Landmark College.

  6. Proliferation of cultured mouse choroid plexus epithelial cells.

    Directory of Open Access Journals (Sweden)

    Basam Z Barkho

    Full Text Available The choroid plexus (ChP epithelium is a multifunctional tissue found in the ventricles of the brain. The major function of the ChP epithelium is to produce cerebrospinal fluid (CSF that bathes and nourishes the central nervous system (CNS. In addition to the CSF, ChP epithelial cells (CPECs produce and secrete numerous neurotrophic factors that support brain homeostasis, such as adult hippocampal neurogenesis. Accordingly, damage and dysfunction to CPECs are thought to accelerate and intensify multiple disease phenotypes, and CPEC regeneration would represent a potential therapeutic approach for these diseases. However, previous reports suggest that CPECs rarely divide, although this has not been extensively studied in response to extrinsic factors. Utilizing a cell-cycle reporter mouse line and live cell imaging, we identified scratch injury and the growth factors insulin-like growth factor 1 (IGF-1 and epidermal growth factor (EGF as extrinsic cues that promote increased CPEC expansion in vitro. Furthermore, we found that IGF-1 and EGF treatment enhances scratch injury-induced proliferation. Finally, we established whole tissue explant cultures and observed that IGF-1 and EGF promote CPEC division within the intact ChP epithelium. We conclude that although CPECs normally have a slow turnover rate, they expand in response to external stimuli such as injury and/or growth factors, which provides a potential avenue for enhancing ChP function after brain injury or neurodegeneration.

  7. Optimization of Gas Supply of CHP Sources of Energy

    OpenAIRE

    Odiņeca, T; Zēbergs, V

    2008-01-01

    The article contains reviews the method of optimization of gas supply of CHP sources of energy - the method of calculation of permissible IRR. It is effective for analyzing the projects of CHP plants’ gasification (also in reconstruction of existing boiler houses). IRR is an effective criterion of profitability of gasification, if the forecast of the consumption of gas is precise. Using the method of calculation of permissible IRR it is possible to find the load limits in which CH...

  8. Exergy diagnosis of coal fired CHP plant with application of neural and regression modelling

    Directory of Open Access Journals (Sweden)

    Stanek Wojciech

    2012-01-01

    Full Text Available Mathematical models of the processes, that proceed in energetic machines and devices, in many cases are very complicated. In such cases, the exact analytical models should be equipped with the auxiliary empirical models that describe those parameters which are difficult to model in a theoretical way. Regression or neural models identified basing on measurements are rather simple and are characterized by relatively short computation time. For this reason they can be effectively applied for simulation and optimization of steering and regulation processes, as well as, for control and thermal diagnosis of operation (eq. power plants or CHP plants. In the paper regression and neural models of thermal processes developed for systems of operation control of thermal plants are presented. Theoretical-empirical model of processes proceeding in coal fired CHP plant have been applied. Simulative calculations basing on these models have been carried out. Results of simulative calculations have been used for the exergetic evaluation of considered power plant. The diagnosis procedure let to investigate the formation of exergy costs in interconnected components of the system of CHP, as well as, investigate the influence of defects in operation of components on exergy losses and on the exergetic cost in other components. [Acknowledgment. The paper has been prepared within the RECENT project (REsearch Center for Energy and New Technologies supported by 7th Framework Programme, Theme 4, Capacities.

  9. Renewables and CHP with District Energy in Support of Sustainable Communities

    Energy Technology Data Exchange (ETDEWEB)

    Snoek, Chris

    2010-09-15

    This paper addresses the powerful idea of connecting many energy users to environmentally optimum energy sources through integrated community energy systems. Such systems require piping networks for distributing thermal energy, i.e., district heating and cooling (DHC) systems. The possibilities and advantages of the application of integrated energy concepts are discussed, including the economic and environmental benefits of integrating localized electrical generating systems (CHP), transportation systems, industrial processes and other thermal energy requirements. Examples of a number of operating systems are provided. Some of the R and D carried out by the IEA Implementing Agreement on District Heating and Cooling is also described.

  10. Development and Demonstration of a New Generation High Efficiency 10kW Stationary Fuel Cell System

    Energy Technology Data Exchange (ETDEWEB)

    Howell, Thomas Russell

    2013-04-30

    The overall project objective is to develop and demonstrate a polymer electrolyte membrane fuel cell combined heat and power (PEMFC CHP) system that provides the foundation for commercial, mass produced units which achieve over 40% electrical efficiency (fuel to electric conversion) from 50-100% load, greater than 70% overall efficiency (fuel to electric energy + usable waste heat energy conversion), have the potential to achieve 40,000 hours durability on all major process components, and can be produced in high volumes at under $400/kW (revised to $750/kW per 2011 DOE estimates) capital cost.

  11. Thermodynamic and thermoeconomic analysis of a system with biomass gasification, solid oxide fuel cell (SOFC) and Stirling engine

    DEFF Research Database (Denmark)

    Rokni, Masoud

    2014-01-01

    Thermodynamic and thermoeconomic investigations of a small-scale integrated gasification solid oxide fuel cell (SOFC) and Stirling engine for combined heat and power (CHP) with a net electric capacity of 120kWe have been performed. Woodchips are used as gasification feedstock to produce syngas......Wh. Furthermore, hot water is considered as a by-product, and the cost of hot water is found to be 0.0214$/kWh. When compared to other renewable systems of similar scales, this result shows that if both SOFC and Stirling engine technology enter the commercialization phase, then they can deliver electricity...

  12. Operation cost and carbon emission reduction analysis of micro-CHP systems in Guangzhou%广州地区应用微型热电联产系统的运行成本及碳减排分析

    Institute of Scientific and Technical Information of China (English)

    解东来; 骆锦辉; 单杰; 聂廷哲

    2016-01-01

    Operation cost and carbon emission reduction are analyzed when four kinds of micro-CHP prod-ucts are applied in Guangzhou.Moreover,the influence of different electricity and gas prices on operation cost was analyzed.The result shows that Ene-Farm has the minimum operation cost with the cost saving ratio reached 14.8%,Ene-Farm Type S has an excellent carbon emission reduction performance with the CO2 emissions reduction ratio reached 37.3%.The sensitivity analysis shows the operation cost of micro-CHP will decrease with the rise of electricity price and the reduction of gas price.%分别考察了广州典型家庭在使用4种不同技术的微型热电联产产品(Ene-Farm、Ene-Farm Type S、Ecowill、WhisperGen)时的运行成本与碳减排效果,并分析电价、气价变化对运行成本的影响.结果表明,Ene-Farm的运行成本最低,经济节约指数达14.8%,Ene-Farm Type S的碳减排效果最好,二氧化碳减排指数达37.3%.灵敏度分析表明,微型热电联产系统的运行成本随着电价的升高、气价的降低而降低.

  13. Energy system analysis of fuel cells and distributed generation

    DEFF Research Database (Denmark)

    Mathiesen, Brian Vad; Lund, Henrik

    2007-01-01

    on the energy system in which they are used. Consequently, coherent energy systems analyses of specific and complete energy systems must be conducted in order to evaluate the benefits of FC technologies and in order to be able to compare alternative solutions. In relation to distributed generation, FC...... can be used for such analyses. Moreover, the chapter presents the results of evaluating the overall system fuel savings achieved by introducing different FC applications into different energy systems. Natural gas-based and hydrogen-based micro FC-CHP, natural gas local FC-CHP plants for district...... technologies have different strengths and weaknesses in different energy systems, but often they do not have the expected effect. Specific analyses of each individual country must be conducted including scenarios of expansion of e.g. wind power in order to evaluate where and when the best use of FC...

  14. Systems cell biology.

    Science.gov (United States)

    Mast, Fred D; Ratushny, Alexander V; Aitchison, John D

    2014-09-15

    Systems cell biology melds high-throughput experimentation with quantitative analysis and modeling to understand many critical processes that contribute to cellular organization and dynamics. Recently, there have been several advances in technology and in the application of modeling approaches that enable the exploration of the dynamic properties of cells. Merging technology and computation offers an opportunity to objectively address unsolved cellular mechanisms, and has revealed emergent properties and helped to gain a more comprehensive and fundamental understanding of cell biology.

  15. COMPARISON OF PADDLE OVER DISK METHOD USED IN THE RELEASE TEST OF TRANSDERMAL DRUG DELIVER SYSTEM BETWEEN USP AND CHP%美国药典与中国药典透皮贴剂释放度桨碟法测定装置的比较

    Institute of Scientific and Technical Information of China (English)

    毛睿; 陈华; 南楠

    2011-01-01

    [目的]对美国药典与中国药典透皮贴剂释放度桨碟法测定装置进行比较.[方法]分别使用美国药典与中国药典桨碟法装置对芬太尼透皮贴剂的释放曲线进行测定,释放介质为2.5 mmol·L-1的磷酸和2.5 mmol·L-1磷酸二氢钾等体积混合溶液900 ml;以TC-C18为固定相的Agilent色谱柱(250 mm ×4.6 mm ×5 wm),含0.2%三乙胺和0.2%磷酸的5 mmol·L-1辛烷基磺酸钠溶液与乙腈的混合溶液(1.3:1)为流动相,流速为1.0 ml·min-1,柱温为25℃,检测波长为210 nm.[结果]对于2.1 mg规格的透皮贴剂采用不同方法所得的释放曲线存在差异.[结论]中国药典桨碟法装置在测量透皮贴剂释放度时不能完全替代美国药典桨碟法装置.%[Objective] To compare the difference of paddle over disk method used in the release test of transdennal drug delivery system between USP and CHP. [Methods] ChP and USP methods were used to test fentanyl transdennal patch, the release media was 900 ml of the mixture of 2.5 mmoloL-1 orthophosphoric acid and 2.5 mmoloL-1 potassium dihydrogen phosphate solution. Agilent column were packed with TC-C18 as solid phase (250 mm×4.6 mm×5 (μm). The mixture of acetonitrile and 0.05 mol·L-1 octylsulfonic sodium solution containing 0.2% triethylamine (1 ∶ 1.3) were used as mobile phase. Hhe flow rate was 1.0 ml·rain-1. The column temperature was 25℃ and the detective wave length was210 nm. [Results] There exists difference between the methods of ChP and USP used in the release test of transdennal drug deliver system in testing 2.1 mg of fentanyl transdennal patch. [Conclusion] The method of USP could not be totally replaced by the method of ChP in the release test of transdennal patch.

  16. Network design optimization of fuel cell systems and distributed energy devices.

    Energy Technology Data Exchange (ETDEWEB)

    Colella, Whitney G.

    2010-07-01

    This research explores the thermodynamics, economics, and environmental impacts of innovative, stationary, polygenerative fuel cell systems (FCSs). Each main report section is split into four subsections. The first subsection, 'Potential Greenhouse Gas (GHG) Impact of Stationary FCSs,' quantifies the degree to which GHG emissions can be reduced at a U.S. regional level with the implementation of different FCS designs. The second subsection, 'Optimizing the Design of Combined Heat and Power (CHP) FCSs,' discusses energy network optimization models that evaluate novel strategies for operating CHP FCSs so as to minimize (1) electricity and heating costs for building owners and (2) emissions of the primary GHG - carbon dioxide (CO{sub 2}). The third subsection, 'Optimizing the Design of Combined Cooling, Heating, and Electric Power (CCHP) FCSs,' is similar to the second subsection but is expanded to include capturing FCS heat with absorptive cooling cycles to produce cooling energy. The fourth subsection, - Thermodynamic and Chemical Engineering Models of CCHP FCSs,' discusses the physics and thermodynamic limits of CCHP FCSs.

  17. Waste Heat Recapture from Supermarket Refrigeration Systems

    Energy Technology Data Exchange (ETDEWEB)

    Fricke, Brian A [ORNL

    2011-11-01

    The objective of this project was to determine the potential energy savings associated with improved utilization of waste heat from supermarket refrigeration systems. Existing and advanced strategies for waste heat recovery in supermarkets were analyzed, including options from advanced sources such as combined heat and power (CHP), micro-turbines and fuel cells.

  18. Solar cell concentrating system

    International Nuclear Information System (INIS)

    This study reviews fabrication techniques and testing facilities for different solar cells under concentration which have been developed and tested. It is also aimed to examine solar energy concentrators which are prospective candidates for photovoltaic concentrator systems. This may provide an impetus to the scientists working in the area of solar cell technology

  19. Modelling a Combined Heat and Power Plant based on Gasification, Micro Gas Turbine and Solid Oxide Fuel Cells

    DEFF Research Database (Denmark)

    Bang-Møller, Christian; Rokni, Masoud

    2009-01-01

    A system level modelling study on two combined heat and power (CHP) systems both based on biomass gasification. One system converts the product gas in a micro gas turbine (MGT) and the other in a combined solid oxide fuel cell (SOFC) and MGT arrangement. An electrochemical model of the SOFC has...

  20. Emissions from decentralised CHP plants 2007 - Energinet.dk Environmental project no. 07/1882. Project report 5 - Emission factors and emission inventory for decentralised CHP production

    Energy Technology Data Exchange (ETDEWEB)

    Nielsen, Malene; Nielsen, Ole-Kenneth; Thomsen, M.

    2010-06-15

    Updated emission factors for decentralised combined heat and power (CHP) plants with a capacity < 25MWe have been estimated based on project emission measurements as well as emission measurements performed in recent years that were collected. The emission factors valid for 2006/2007 have been estimated for the plant technologies: Municipal solid waste (MSW) incineration plants, plants combusting straw or wood, natural gas fuelled reciprocating engines, biogas fuelled engines, natural gas fuelled gas turbines, gas oil fuelled reciprocating engines, gas oil fuelled gas turbines, steam turbines combusting residual oil and reciprocating engines combusting biomass producer gas based on wood. The emission factors for MSW incineration plants are much lower than the emission factors that were estimated for year 2000. The considerable reduction in the emission factors is a result of lower emission limit values in Danish legislation since 2006 that has lead to installation of new and improved flue gas cleaning systems in most MSW incineration plants. For CHP plants combusting wood or straw no major technical improvements have been implemented. The emission factors for natural gas fuelled reciprocating engines have been reduced since year 2000 as a result of technical improvements that have been carried out due to lower emission limit values in Danish legislation. The NO{sub x} emission factor for natural gas fuelled gas turbines has decreased 62 % since year 2000. This is a result of installation of low-NO{sub x} burners in almost all gas turbines that has been necessary to meet new emission limits in Danish legislation. The emission measurements programme included screening of the emissions of HCB, PCB, PCDD/-F and PBDD/-F. Compared to the Danish national emission decentralized CHP plants are major emission sources for CH{sub 4}, NO{sub x}, SO{sub 2}, heavy metals and HCB. (author)

  1. CHP and District Cooling: An Assessment of Market and Policy Potential in India

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-07-01

    This report contains an assessment of India's CHP/DC status and recommendations for addressing barriers to allow India to meet its energy efficiency targets. Such barriers include a lack of governmental emphasis on CHP, the absence of a clear methodology for calculating CO2 emission reductions from CHP/DHC, and a tax and duty structure for CHP capital equipment that is not as attractive as for other renewable energy technologies.

  2. Energy policy responses to the climate change challenge: The consistency of European CHP, renewables and energy efficiency policies

    International Nuclear Information System (INIS)

    This report is Volume 14 of individual reports of the Shared Analysis Project prepared for the European Commission, Directorate General for Energy. The three major objectives of the project were: to design a common framework of energy analysis that aimed to involve all Member States and the experts of industrial research groups (the shared approach to energy analysis); To analyse generic EU-wide issues important for energy policy and for future energy demand and production, putting particular emphasis on world energy market trends, strategic energy policy responses to the Kyoto process, and evaluation of response strategies to increasing energy import dependence and to climate change activities; to carry out quantitative analyses of energy trends and scenarios as an input for discussion. The present volume considers three main issues concerning energy policy responses to the climate change challenge: the penetration of CHP and renewables according to official objectives, focusing on infrastructure and institutions rather than technology; the consistency of promotion of CHP, renewables and energy savings at the same time; consumers' choices and priorities in a liberalised market. The volume describes examples of policies in several Member States for these technologies with emphasis on CHP for both large-scale and small-scale district heating systems. The penetration of CHP technologies is analysed quantitatively using a traditional optimisation model approach for stylised regions with heat markets suitable for CHP and facing a competitive European market for electricity. The Joint Final Report of the project, titled 'Economic Foundations for Energy Policy' is published as a Special Issue of Energy in Europe, December 1999. All reports are available on the Internet, www.shared-analysis.fhg.de/ The project started in January 1998, involving about 100 months of scientific labour. The project consortium consisted of nine member institutes co-ordinated by the Fraunhofer

  3. Energy policy responses to the climate change challenge: The consistency of European CHP, renewables and energy efficiency policies

    Energy Technology Data Exchange (ETDEWEB)

    Grohnheit, P.E.

    1999-09-01

    This report is Volume 14 of individual reports of the Shared Analysis Project prepared for the European Commission, Directorate General for Energy. The three major objectives of the project were: to design a common framework of energy analysis that aimed to involve all Member States and the experts of industrial research groups (the shared approach to energy analysis); To analyse generic EU-wide issues important for energy policy and for future energy demand and production, putting particular emphasis on world energy market trends, strategic energy policy responses to the Kyoto process, and evaluation of response strategies to increasing energy import dependence and to climate change activities; to carry out quantitative analyses of energy trends and scenarios as an input for discussion. The present volume considers three main issues concerning energy policy responses to the climate change challenge: the penetration of CHP and renewables according to official objectives, focusing on infrastructure and institutions rather than technology; the consistency of promotion of CHP, renewables and energy savings at the same time; consumers' choices and priorities in a liberalised market. The volume describes examples of policies in several Member States for these technologies with emphasis on CHP for both large-scale and small-scale district heating systems. The penetration of CHP technologies is analysed quantitatively using a traditional optimisation model approach for stylised regions with heat markets suitable for CHP and facing a competitive European market for electricity. The Joint Final Report of the project, titled 'Economic Foundations for Energy Policy' is published as a Special Issue of Energy in Europe, December 1999. All reports are available on the Internet, www.shared-analysis.fhg.de/ The project started in January 1998, involving about 100 months of scientific labour. The project consortium consisted of nine member institutes co-ordinated by

  4. A new approach in CHP steam turbines thermodynamic cycles computations

    Directory of Open Access Journals (Sweden)

    Grković Vojin R.

    2012-01-01

    Full Text Available This paper presents a new approach in mathematical modeling of thermodynamic cycles and electric power of utility district-heating and cogeneration steam turbines. The approach is based on the application of the dimensionless mass flows, which describe the thermodynamic cycle of a combined heat and power steam turbine. The mass flows are calculated relative to the mass flow to low pressure turbine. The procedure introduces the extraction mass flow load parameter νh which clearly indicates the energy transformation process, as well as the cogeneration turbine design features, but also its fitness for the electrical energy system requirements. The presented approach allows fast computations, as well as direct calculation of the selected energy efficiency indicators. The approach is exemplified with the calculation results of the district heat power to electric power ratio, as well as the cycle efficiency, versus νh. The influence of νh on the conformity of a combined heat and power turbine to the grid requirements is also analyzed and discussed. [Projekat Ministarstva nauke Republike Srbije, br. 33049: Development of CHP demonstration plant with gasification of biomass

  5. Cell Maintenance Systems

    Science.gov (United States)

    Morrison, D. R.

    1985-01-01

    Living human cells require attachment to a suitable surface and special culture conditions in order to grow. These requirements are modified and amplified when cells are taken into a weightless environment. Special handling and maintenance systems are required for routine laboratory procedures conducted in the Orbiter and in the Spacelab. Methods were developed to maintain cells in special incubators designed for the Orbiter middeck, however, electrophoresis and other experiments require cells to be harvested off of the culture substrate before they can be processed or used. The cell transport assembly (CTA) was flown on STS-8, and results show that improvements are required to maintain adequate numbers of cells in this device longer than 48 hours. The life sciences middeck centrifuge probably can be used, but modifications will be required to transfer cells from the CTA and keep the cells sterile. Automated systems such as the Skylab SO-15 flight hardware and crew operated systems are being evaluated for use on the Space Shuttle, Spacelab, and Space Station research modules.

  6. Solid Oxide Cell and Stack Testing, Safety and Quality Assurance (SOCTESQA)

    DEFF Research Database (Denmark)

    Auer, C.; Lang, M.; Couturier, K.;

    2015-01-01

    the fuel cell (SOFC), in the electrolysis (SOEC) and in the reversible SOFC/SOEC mode are addressed. This covers the wide field of power generation systems, e.g. stationary SOFC µ-CHP, mobile SOFC APU and SOFC/SOEC power-to-gas systems. The paper presents the results which have been achieved so far in...

  7. Solid Oxide Cell and Stack Testing, Safety and Quality Assurance (SOCTESQA)

    DEFF Research Database (Denmark)

    Auer, C.; Lang, M.; Couturier, K.;

    2015-01-01

    in the fuel cell (SOFC), in the electrolysis (SOEC) and in the reversible SOFC/SOEC mode are addressed. This covers the wide field of power generation systems, e.g. stationary SOFC µ-CHP, mobile SOFC APU and SOFC/SOEC power-to-gas systems. The paper presents the results which have been achieved so far...

  8. Solid Oxide Cell and Stack Testing, Safety and Quality Assurance (SOCTESQA)

    DEFF Research Database (Denmark)

    Auer, C.; Lang, M.; Couturier, K.;

    2015-01-01

    /stack assembly in the fuel cell (SOFC), in the electrolysis (SOEC) and in the combined SOFC/SOEC mode are addressed. This covers the wide field of power generation systems, e.g. stationary SOFC µ-CHP, mobile SOFC APU and SOFC/SOEC power-to-gas systems. This paper presents the results which have been achieved so...

  9. District Heating and CHP - Local Possibilities for Global Climate Change Mitigation

    Energy Technology Data Exchange (ETDEWEB)

    Difs, Kristina

    2010-07-01

    Global warming, in combination with increasing energy demand and higher energy prices, makes it necessary to change the energy use. To secure the energy supply and to develop sustainable societies, construction of energy-efficient systems is at the same time most vital. The aim of this thesis is therefore to identify how a local energy company, producing district heating (DH), district cooling (DC) and electricity in combined heat and power (CHP) plants, can contribute to resource-efficient energy systems and cost-effective reductions of global carbon dioxide (CO{sub 2}) emissions, along with its customers. Analyses have been performed on how a local energy company can optimise their DH and DC production and what supply-side and demand-side measures can lead to energy-efficient systems in combination with economic and climate change benefits. The energy company in focus is located in Linkoeping, Sweden. Optimisation models, such as MODEST and reMIND, have been used for analysing the energy systems. Scenario and sensitivity analyses have also been performed for evaluation of the robustness of the energy systems studied. For all analyses a European energy system perspective was applied, where a fully deregulated European electricity market with no bottlenecks or other system failures was assumed. In this thesis it is concluded that of the DH-supply technologies studied, the biomass gasification applications and the natural gas combined cycle (NGCC) CHP are the technologies with the largest global CO{sub 2} reduction potential, while the biomass-fuelled plant that only produces heat is the investment with the smallest global CO{sub 2} reduction and savings potential. However, the global CO{sub 2} reduction potential for the biomass integrated gasification combined cycle (BIGCC) CHP and NGCC CHP, the two technologies with highest electricity efficiencies, is highly dependent on the assumptions made about marginal European electricity production. Regarding the effect on

  10. Optimal power flow based TU/CHP/PV/WPP coordination in view of wind speed, solar irradiance and load correlations

    International Nuclear Information System (INIS)

    Highlights: • Formulate probabilistic OPF with VPE, multi-fuel options, POZs, FOR of CHP units. • Propose a new powerful optimization method based on enhanced black hole algorithm. • Coordinate of TUs, WPPs, PVs and CHP units together in the proposed problem. • Evaluate the impacts of inputs’ uncertainties and their correlations on the POPF. • Use the 2m + 1 point estimated method. - Abstract: This paper addresses a novel probabilistic optimisation framework for handling power system uncertainties in the optimal power flow (OPF) problem that considers all the essential factors of great impact in the OPF problem. The object is to study and model the correlation and fluctuation of load demands, photovoltaic (PV) and wind power plants (WPPs) which have an important influence on transmission lines and bus voltages. Moreover, as an important tool of saving waste heat energy in the thermoelectric power plant, the power networks share of combined heat and power (CHP) has increased dramatically in the past decade. So, the probabilistic OPF (POPF) problem considering valve point effects, multi-fuel options and prohibited zones of thermal units (TUs) is firstly formulated. The PV, WPP and CHP units are also modeled. Then, a new method utilizing enhanced binary black hole (EBBH) algorithm and 2m + 1 point estimated method is proposed to solve this problem and to handle the random nature of solar irradiance, wind speed and load of consumers. The correlation between input random variables is considered using a correlation matrix. Finally, numerical results are presented and considered regarding the IEEE 118-busses, including PV, WPP, CHP and TU at several busses. The simulation and comparison results obtained demonstrate the broad advantages and feasibility of the suggested framework in the presence of dependent non-Gaussian distribution of random variables

  11. Molecular Characterization of a Bacteriophage (Chp2) from Chlamydia psittaci

    OpenAIRE

    Liu, B. L.; Everson, J. S.; Fane, B.; Giannikopoulou, P.; Vretou, E.; Lambden, P R; Clarke, I N

    2000-01-01

    Comparisons of the proteome of abortifacient Chlamydia psittaci isolates from sheep by two-dimensional gel electrophoresis identified a novel abundant protein with a molecular mass of 61.4 kDa and an isoelectric point of 6.41. C-terminal sequence analysis of this protein yielded a short peptide sequence that had an identical match to the viral coat protein (VP1) of the avian chlamydiaphage Chp1. Electron microscope studies revealed the presence of a 25-nm-diameter bacteriophage (Chp2) with no...

  12. Technical Analysis of Installed Micro-Combined Heat and Power Fuel-Cell System

    Energy Technology Data Exchange (ETDEWEB)

    Brooks, Kriston P.; Makhmalbaf, Atefe

    2014-10-31

    Combined heat and power fuel cell systems (CHP-FCSs) provide consistent electrical power and hot water with greater efficiency and lower emissions than alternative sources. These systems can be used either as baseload, grid-connected, or as off-the-grid power sources. This report presents a technical analysis of 5 kWe CHP-FCSs installed in different locations in the U.S. At some sites as many as five 5 kWe system is used to provide up to 25kWe of power. Systems in this power range are considered “micro”-CHP-FCS. To better assess performance of micro-CHP-FCS and understand their benefits, the U.S. Department of Energy worked with ClearEdge Power to install fifteen 5-kWe PBI high temperature PEM fuel cells (CE5 models) in the commercial markets of California and Oregon. Pacific Northwest National Laboratory evaluated these systems in terms of their economics, operations, and technical performance. These units were monitored from September 2011 until June 2013. During this time, about 190,000 hours of data were collected and more than 17 billion data points were analyzed. Beginning in July 2013, ten of these systems were gradually replaced with ungraded systems (M5 models) containing phosphoric acid fuel cell technology. The new units were monitored until June 2014 until they went offline because ClearEdge was bought by Doosan at the time and the new manufacturer did not continue to support data collection and maintenance of these units. During these two phases, data was collected at once per second and data analysis techniques were applied to understand behavior of these systems. The results of this analysis indicate that systems installed in the second phase of this demonstration performed much better in terms of availability, consistency in generation, and reliability. The average net electrical power output increased from 4.1 to 4.9 kWe, net heat recovery from 4.7 to 5.4 kWth, and system availability improved from 94% to 95%. The average net system electric

  13. Integrated HT-PEMFC and multi-fuel reformer for micro CHP. Final report

    Energy Technology Data Exchange (ETDEWEB)

    2010-07-01

    reformed both methane and biogas although the efficiency was low, on the order of 15% due to excessive slip and heat losses. The construction and test of an integrated micro CHP system revealed several problems with the core technology. Therefore, rather than working with the integrated system, individual system components were tested separately. In spite of the problems with the reformer and the fuel cell stack the system was successfully operated and an electric efficiency of 18%{sub LHV} was demonstrated. (Author)

  14. 3D-animaation käyttö CHP-voimalan visualisoinnissa : esimerkkinä GASEK CHP

    OpenAIRE

    Muilu, Jaakko

    2012-01-01

    Opinnäytetyön tavoitteena oli suunnitella ja toteuttaa GASEK Oy:lle animaatio kolmiulotteisella grafiikalla. Animaation tarkoitus oli esitellä GASEK Oy:n CHP-voimalaitosta, jossa sekapuuhakkeesta tuotetaan lämpöä ja sähköä. Työn pääpainona oli visualisoida CHP-voimalassa tapahtuva kaasutusprosessi ja puukaasun virtaus laitteistossa. Opinnäytetyön käytännön osuuksiin kuuluivat animaation suunnittelu, toteutus ja videon luominen. The aim of the thesis was to plan and produce an animatio...

  15. Modelling biomass-fuelled small-scale CHP plants for process synthesis optimisation

    OpenAIRE

    Savola, Tuula

    2007-01-01

    In this work possible process improvements for biomass-fuelled small-scale combined heat and power (CHP) plants are evaluated and a new mixed integer nonlinear programming (MINLP) model for process synthesis optimisation of these processes is presented. Small-scale (1-20 MWe) CHP plants are of interest, as in Finland the potential to increase the CHP production is in converting small heating units to CHP production. However, the profitability of these small-scale CHP investments should be hig...

  16. Sustainable energy supply to very low-energy buildings by means of Micro-CHP technologies and solar thermal energy

    OpenAIRE

    Sicre, Benoit Ghislain

    2005-01-01

    Description and assessment of technology-related concepts aiming at improving the energy conservation in residential buildings. Explanation of the method and discussion of the whole-year simulation results for SOFC micro-CHP systems and Stirling engines in relation with single-family houses of different thermal insulation standards. Benchmark with conventional energy supply systems. Computation of allowable investment costs Beschreibung und Beurteilung unter technischen, ökonom...

  17. Demonstration Stirling Engine based Micro-CHP with ultra-low emissions

    Energy Technology Data Exchange (ETDEWEB)

    Oeberg, Rolf; Olsson, Fredrik [Carl Bro Energikonsult AB (Sweden); Paalsson, Magnus [Lund Inst. of Technology (Sweden)

    2004-03-01

    This project has been initiated in order to develop a new type of natural gas fired low emission combustion system for a Stirling engine CHP-unit, and to demonstrate and evaluate the unit with the newly developed combustion system in a CHP application. The Stirling engine technology is well developed, but mostly used in special applications and CHP-applications are scarce. The very low exhaust emissions with the new combustion system would make the Stirling engine very suitable for installation in as a CHP-unit in domestic areas. The Stirling engine used in the project has been a V161 engine produced by Solo Kleinmotoren GmbH in Sindelfingen. The unit has a nominal output of 7,5 kW{sub el} and 20 kW{sub heat} (Hot water). The new combustion system was developed at Lund University and the very strict emission targets that were set up could be achieved, both in the laboratory tests and during the site-testing period. Typical performance and emission figures measured at the site installation are: Generator output (kW): 7,3; Hot water output (kW): 15; El. efficiency (%): 25,4; Total efficiency (%): 77,8; NO{sub x} (ppm): 14; CO (ppm): 112; HC (ppm): < 1; O{sub 2} (%): 8,0; Noise level 1 m from the unit (dBA): 83. The NO{sub x} emissions were reduced with almost 97 % as compared to a standard Stirling combustion system. The emission figures are considerably lower than what could be achieved in an internal combustion engine of similar size with an oxidation catalyst (report SGC 106), while the performance figures are similar for the two technologies. The site testing was carried out during a period of 1,5 year at a site owned by Goeteborg Energi. The site comprises a building structure with workshops, offices etc. covering a ground area of 2,500 m{sup 2}. A gas fired boiler with an output of 250 kW supplies hot water to a local grid for heating and tap water. The annual heat demand is typically 285 MWh and the hot water temperatures are normally 60-80 deg C. The site

  18. A Stochastic Unit Commitment Model for a Local CHP Plant

    DEFF Research Database (Denmark)

    Ravn, Hans V.; Riisom, Jannik; Schaumburg-Müller, Camilla

    2005-01-01

    Local CHP development in Denmark has during the 90’s been characterised by large growth primarily due to government subsidies in the form of feed-in tariffs. In line with the liberalisation process in the EU, Danish local CHPs of a certain size must operate on market terms from 2005. This paper...

  19. IVO`s CHP know-how: experience, inventions, patents

    Energy Technology Data Exchange (ETDEWEB)

    Aeijaelae, M.; Ohtonen, V. [ed.

    1997-11-01

    IVO can justly claim mastery in the co-generation of district heat and electricity - CHP. As well as looking at the issue from the viewpoint of planners, builders and operators, IVO`s engineers also view power plants through the eyes of the product developer and inventor. This approach has resulted in successful power plant configurations, inventions and patents and visions

  20. Anode gas recirculation for improving the performance and cost of a 5-kW solid oxide fuel cell system

    Science.gov (United States)

    Torii, Ryohei; Tachikawa, Yuya; Sasaki, Kazunari; Ito, Kohei

    2016-09-01

    Solid oxide fuel cells (SOFCs) have the potential to efficiently convert chemical energy into electricity and heat and are expected to be implemented in stationary combined heat and power (CHP) systems. This paper presents the heat balance analysis for a 5-kW medium-sized integrated SOFC system and the evaluation of the effect of anode gas recirculation on the system performance. The risk of carbon deposition on an SOFC anode due to anode gas recirculation is also assessed using the C-H-O diagram obtained from thermodynamic equilibrium calculations. These results suggest that a higher recirculation ratio increases net fuel utilization and improves the electrical efficiency of the SOFC system. Furthermore, cost simulation of the SOFC system and comparison with the cost of electricity supply by a power grid indicates that the capital cost is sufficiently low to popularize the SOFC system in terms of the total cost over one decade.

  1. The Smart Energy System

    DEFF Research Database (Denmark)

    Jurowetzki, Roman; Dyrelund, Anders; Hummelmose, Lars;

    on the synergies which are obtained through integration of the district heating and district cooling, gas, and electricity grid into a single smart energy system. Besides documenting the technology and innovation strengths that Danish companies possess particularly relating to wind, district heating, CHP...... production, large scale solar heat, fuel cells, heat storage, waste incineration, among others, the report draws a picture of Denmark as a research and development hub for smart energy system solutions....

  2. Policy schemes, operational strategies and system integration of residential co-generation fuel cells

    DEFF Research Database (Denmark)

    Hansen, Lise-Lotte Pade; Schröder, Sascha Thorsten; Münster, Marie;

    2013-01-01

    This study presents a holistic approach for the commercialisation of fuel cells for stationary applications. We focus our analyses on microCHP based on SOFC units fired with natural gas. We analyse the interaction of operational strategies under different ownership arrangements, required support...... levels and system integration aspects. The operational strategies, support mechanisms and ownership arrangements have been identified through actor analysis involving experts from Denmark, France and Portugal. With regard to operational strategies, the actor analyses led us to distinguishing between...... a heat-driven strategy, with and without time-differentiated tariffs, and an electricity price driven strategy for the operation as a virtual power plant. The corresponding support schemes identified cover feed-in tariffs, net metering and feed-in premiums. Additionally, the interplay of the micro...

  3. Toxin-antitoxin loci as stress-response-elements: ChpAK/MazF and ChpBK cleave translated RNAs and are counteracted by tmRNA

    DEFF Research Database (Denmark)

    Christensen, S.K.; Pedersen, K.; Hansen, Flemming G.;

    2003-01-01

    . coli. We show that both proteins inhibit translation by inducing cleavage of translated mRNAs. Consistently, the inhibitory effect of the proteins was counteracted by tmRNA. Amino acid starvation induced strong transcription of chpA that depended on Lon protease but not on ppGpp. Simultaneously, Chp...

  4. Retrofitting micro gas turbines for wet operation. A way to increase operational flexibility in distributed CHP plants

    International Nuclear Information System (INIS)

    Highlights: • Thermodynamic modeling of wet micro gas turbines. • Technoeconomic analysis of mGTs retrofits for wet operation. • Demonstration of the operational flexibility increase due to wet operation. • In depth case study analysis of a CHP system in 15-min time-intervals. • Sensitivity analysis on all major economic parameters of wet operation. - Abstract: It is generally accepted that only flexible CHP plants could be a viable option in an electrical system with high penetration of variable renewables. Variable power-to-heat-ratios and decoupled power and heat generation will be basic requirements. Currently, the most common way to fulfill these specifications is the use of heat storage devices, whereas wet operation of gas turbines is an alternative way to achieve both goals. The current work is an analysis of a micro gas turbine adapted to operate with steam injection. A thermodynamic model is developed and a typical apartments building in Berlin, Germany is chosen as a case study. The study presumes the existence of a micro gas turbine and analyzes the results of its adaptation for wet operation. The environmental and economic performance of the new system is compared to that of its commercial counterpart. It is shown that the retrofitted turbine has longer annual operation time and higher electrical energy generation. The retrofit also proves to be an attractive investment for the German CHP market with internal rates of return reaching almost 20%

  5. A gas utility approach to fuel cell commercialisation

    International Nuclear Information System (INIS)

    The most attractive application for fuel cells seems to be in decentralised combined heat and power generation (CHP). The market for energy efficient CHP is growing, partly as a result of the wish to decrease CO2 emissions. Gas utilities are facing this development and can react in different ways. One of these is to operate natural gas powered CHPs themselves. The attractiveness of fuel cell powered CHPs for gas utilities depends firstly on the economy and reliability of CHP in general in the markets considered and secondly on the competitiveness of fuel cells versus, for example, the gas engine and gas turbine based CHP. Important possible activities for a gas utility in relation to fuel cell commercialisation are helping develop the market for CHP, defining the requirements for fuel cells in CHP and helping the fuel cell manufacturers to build up practical experience by participating in demonstration projects. The situation in the Netherlands will be used for examples. (orig.)

  6. Multiple Sequence Elements Facilitate Chp Rho GTPase Subcellular Location, Membrane Association, and Transforming Activity

    OpenAIRE

    Chenette, Emily J.; Mitin, Natalia Y.; Der, Channing J.

    2006-01-01

    Cdc42 homologous protein (Chp) is a member of the Rho family of small GTPases and shares significant sequence and functional similarity with Cdc42. However, unlike classical Rho GTPases, we recently found that Chp depends on palmitoylation, rather than prenylation, for association with cellular membranes. Because palmitoylation alone is typically not sufficient to promote membrane association, we evaluated the possibility that other carboxy-terminal residues facilitate Chp subcellular associa...

  7. Translating Hardware Process Algebras into Standard Process Algebras : Illustration with CHP and LOTOS

    OpenAIRE

    Salaün, Gwen; Serwe, Wendelin

    2005-01-01

    A natural approach for the description of asynchronous hardware designs are hardware process algebras, such as Martin's CHP (Communicating Hardware Processes), Tangram, or BALSA, which are extensions of standard process algebras with particular operators exploiting the implementation of synchronisation using handshake protocols. In this research report, we give a structural operational semantics for value-passing CHP. Compared to existing semantics of CHP defined by translation into Petri net...

  8. Evaluation of Exhaust Gas Condensing Economizer Installation at Riga CHP Plants

    OpenAIRE

    Zigurs, Aris; Kunickis, Maris; Balodis, Maris; Linkevics, Olegs; Stuklis, Ilmars; Ivanova, Polina

    2015-01-01

    In this study, passive exhaust gas condensing economizer installation is evaluated at Riga CHP plants No. 1 and No. 2 to increase efficiency of heat only boilers (HOBs). Five options are investigated: two options for Riga CHP plant No. 1 and three options for Riga CHP plant No. 2. The study provides the analysis of HOBs operation statistics, determination of HOBs operation trends, development of production programmes, as well as economic and sensitivity analysis of the considered options. Bas...

  9. A chromodomain protein, Chp1, is required for the establishment of heterochromatin in fission yeast

    OpenAIRE

    Sadaie, Mahito; Iida, Tetsushi; URANO, TAKESHI; Nakayama, Jun-ichi

    2004-01-01

    The chromodomain is a conserved motif that functions in the epigenetic control of gene expression. Here, we report the functional characterization of a chromodomain protein, Chp1, in the heterochromatin assembly in fission yeast. We show that Chp1 is a structural component of three heterochromatic regions—centromeres, the mating-type region, and telomeres—and that its localization in these regions is dependent on the histone methyltransferase Clr4. Although deletion of the chp1+ gene causes c...

  10. Preparation of Yeast Hydrolysate Enriched in Cyclo-His-Pro (CHP) by Enzymatic Hydrolysis and Evaluation of Its Functionality

    OpenAIRE

    Lee, Hyun Jung; Son, Heung Soo; Park, Chung; Suh, Hyung Joo

    2015-01-01

    In this study, we attempted to enrich cyclo-His-Pro (CHP) using enzymatic hydrolysis of yeast and to evaluate the functionality of yeast hydrolysate (YH)-enriched CHP. Flavourzyme offered a better performance in enhancing CHP content than other proteases. The CHP enrichment conditions were optimized as follows: addition of 1% Flavourzyme, 48-h incubation at 60°C, and pH 6.0. The CHP content significantly increased by 20-fold after ultra-filtration (UF). Maximal CHP translation was obtained af...

  11. ASSESSMENT OF COMBINED HEAT AND POWER SYSTEM "PREMIUM POWER" APPLICATIONS IN CALIFORNIA

    OpenAIRE

    Norwood, Zack

    2010-01-01

    The effectiveness of combined heat and power (CHP) systems for power interruption intolerant, "premium power," facilities is the focus of this study. Through three real-world case studies and economic cost minimization modeling, the economic and environmental performance of "premium power" CHP is analyzed. The results of the analysis for a brewery, data center, and hospital lead to some interesting conclusions about CHP limited to the specific CHP technologies installed at those sites. Firs...

  12. Large-scale integration of wind power into different energy systems

    Energy Technology Data Exchange (ETDEWEB)

    Lund, H. [Aalborg University (Denmark). Dept. of Development and Planning

    2005-10-01

    The paper presents the ability of different energy systems and regulation strategies to integrate wind power. The ability is expressed by the following three factors: the degree of electricity excess production caused by fluctuations in wind and Combined Heat and Power (CHP) heat demands, the ability to utilise wind power to reduce CO{sub 2} emission in the system, and the ability to benefit from exchange of electricity on the market. Energy systems and regulation strategies are analysed in the range of a wind power input from 0 to 100% of the electricity demand. Based on the Danish energy system, in which 50% of the electricity demand is produced in CHP, a number of future energy systems with CO{sub 2} reduction potentials are analysed, i.e. systems with more CHP, systems using electricity for transportation (battery or hydrogen vehicles) and systems with fuel-cell technologies. For the present and such potential future energy systems different regulation strategies have been analysed, i.e. the inclusion of small CHP plants into the regulation task of electricity balancing and ancillary grid stability services and investments in electric heating, heat pumps and heat storage capacity. The results of the analyses make it possible to compare short-term and long-term potentials of different strategies of large-scale integration of wind power. (author)

  13. Advanced CHP Control Algorithms: Scope Specification

    Energy Technology Data Exchange (ETDEWEB)

    Katipamula, Srinivas; Brambley, Michael R.

    2006-04-28

    The primary objective of this multiyear project is to develop algorithms for combined heat and power systems to ensure optimal performance, increase reliability, and lead to the goal of clean, efficient, reliable and affordable next generation energy systems.

  14. Fuel cell based hybrid systems

    OpenAIRE

    Davat, B.; Astier, S.; Bethoux, O.; CANDUSSO,D; Coquery, G.; DE-BERNARDINIS, A; DRUART, F; Francois, M; GARCIA ARREGUI, F; Harel, F.

    2009-01-01

    This paper presents different works which are currently developed in the field of fuel cell hybrid systems indifferent public laboratories in France. These works are presented in three sections corresponding to: 1. Hybrid fuel cell/battery or supercapacitor power sources; 2. Fuel cell multistack power sources; 3. Fuel cell in hybrid power systems for distributed generation. The presented works combine simulation and experimental results.

  15. A Pilot Evaluation of Small Group Challenging Horizons Program (CHP): A Randomized Trial

    Science.gov (United States)

    Langberg, Joshua M.; Smith, Bradley H.; Bogle, Kristin E.; Schmidt, Jonathan D.; Cole, Wesley R.; Pender, Carolyn A. S.

    2007-01-01

    This study examined the efficacy of an after-school program, the Challenging Horizons Program (CHP), that met four days a week and focused on improving organization, academic skills, and classroom behavior. The CHP was compared with a community control that included involvement in a district-run after-school program that met one to three days a…

  16. A closed-form expression for the optimal capacity of CHP

    OpenAIRE

    Arie ten Cate

    2009-01-01

    In this memorandum the optimal capacity of Combined Heat and Power (CHP) is derived, using a simple model with an analytical solution. The solution is expressed as the fraction of the time during which the heat demand exceeds the optimal CHP heat production capacity.

  17. Implementation strategy for small CHP-plants in a competitive market

    DEFF Research Database (Denmark)

    Lund, Henrik; Šiupšinskas, G.; Martinaitis, V.

    2005-01-01

    The article analyses the conditions for the replacement of boilers in the existing district-heating supplies with combined heat-and-power production (CHP) in Lithuania.......The article analyses the conditions for the replacement of boilers in the existing district-heating supplies with combined heat-and-power production (CHP) in Lithuania....

  18. Experimental development, 1D CFD simulation and energetic analysis of a 15 kw micro-CHP unit based on reciprocating internal combustion engine

    International Nuclear Information System (INIS)

    Cogeneration is commonly recognized as one of the most effective solutions to achieve the increasingly stringent reduction in primary energy consumption and greenhouse emissions. This characteristic led to the adoption of specific directives promoting this technique. In addition, a strategic role in power reliability is recognized to distributed generation. The study and prototyping of cogeneration plants, therefore, has involved many research centres. This paper deals with energetic aspects of CHP referring to the study of a 15 kW micro-CHP plant based on a LPG reciprocating engine designed, built and grid connected. The plant consists of a heat recovery system characterized by a single water circuit recovering heat from exhaust gases, from engine coolant and from the energy radiated by the engine within the shell hosting the plant. Some tests were carried out at whole open throttle and the experimental data were collected. However it was needed to perform a 1D thermo-fluid dynamics simulation of the engine to completely characterize the micro-CHP. As the heat actually recovered depends on the user's thermal load, particularly from the required temperature's level, a comparison of the results for six types of users were performed: residential, hospital, office, commercial, sports, hotel. Both Italian legislative indexes IRE and LT were evaluated, as defined by A.E.E.G resolution n. 42/02 and subsequent updates, as well as the plant's total Primary Energy Saving. - Highlights: • This paper deals with energetic aspects of CHP referring to the study of a 15 kW micro-CHP plant. • The 15 kW micro-CHP plant is based on a GPL reciprocating engine designed, built and grid connected. • Some tests were carried out at whole open throttle and the experimental data were collected. • It was needed to perform a 1D thermo-fluid dynamics simulation of the engine to completely characterize the micro-CHP. • The analysed solution is particularly suited for

  19. Savukaasujen hiilidioksidin talteenottoprosessin vaikutukset olemassa olevaan monipolttoaine-CHP-voimalaitokseen

    OpenAIRE

    Keskitalo, E. (Esa)

    2013-01-01

    Kasvihuonepäästöjen rajoittaminen on yksi tämän hetken suurista haasteista. Suomi on EU:n jäsenmaana sitoutunut vähentämään kasvihuonepäästöjä 20 % vuoteen 2020 mennessä. Tästä osuudesta on tavoitteena saada talteen 10 % hiilen talteenotto- ja varastointimenetelmien (CCS) avulla. Diplomityön tarkoituksena oli tutkia, mitä teknisiä ratkaisuja on olemassa hiilidioksidin talteenotolle monipolttoaine-CHP-voimalaitoksen savukaasuista. Teoriaosiossa käytiin ensin läpi yleisellä tasolla CO2:n ta...

  20. CHP from Updraft Gasifier and Stirling Engine

    DEFF Research Database (Denmark)

    Jensen, N.; Werling, J.; Carlsen, Henrik;

    2002-01-01

    engine heat exchanger, can be eliminated and the overall electric efficiency of the system can be improved. At the Technical University of Denmark a Stirling engine fueled by gasification gas has been developed. In this engine the combustion system and the geometry of the hot heat exchanger...... simulation model has been developed as a tool to analyse a system combining the Stirling engine with a gasifier. The paper presents simulation results for the demonstration plant at typical operating conditions. A result from the simulation is that a net electric efficiency of 17,7 % based on the higher......The combination of thermal gasification with a Stirling engine is an interesting concept for use in small combined heat and power plants based on biomass. By combining the two technologies a synergism can potentially be achieved. Technical problems, e.g. gas cleaning and fouling of the Stirling...

  1. Systems biomechanics of the cell

    CERN Document Server

    Maly, Ivan V

    2013-01-01

    Systems Biomechanics of the Cell attempts to outline systems biomechanics of the cell as an emergent and promising discipline. The new field owes conceptually to cell mechanics, organism-level systems biomechanics, and biology of biochemical systems. Its distinct methodology is to elucidate the structure and behavior of the cell by analyzing the unintuitive collective effects of elementary physical forces that interact within the heritable cellular framework. The problematics amenable to this approach includes the variety of cellular activities that involve the form and movement of the cell body and boundary (nucleus, centrosome, microtubules, cortex, and membrane). Among the elementary system effects in the biomechanics of the cell, instability of symmetry, emergent irreversibility, and multiperiodic dissipative motion can be noted. Research results from recent journal articles are placed in this unifying framework. It is suggested that the emergent discipline has the potential to expand the spectrum of ques...

  2. Emissions from decentralised CHP plants 2007 - Energinet.dk Environmental project no. 07/1882

    DEFF Research Database (Denmark)

    Nielsen, Malene; Nielsen, Ole-Kenneth; Thomsen, Marianne

    estimated for the plant technologies: Municipal solid waste (MSW) incineration plants, plants combusting straw or wood, natural gas fuelled reciprocating engines, biogas fuelled engines, natural gas fuelled gas turbines, gas oil fuelled reciprocating engines, gas oil fuelled gas turbines, steam turbines...... combusting residual oil and reciprocating engines combusting biomass producer gas based on wood. The emission factors for MSW incineration plants are much lower than the emission factors that were estimated for year 2000. The considerable reduction in the emission factors is a result of lower emission limit...... values in Danish legislation since 2006 that has lead to installation of new and improved flue gas cleaning systems in most MSW incineration plants. For CHP plants combusting wood or straw no major technical improvements have been implemented. The emission factors for natural gas fuelled reciprocating...

  3. Energy and economic effects of CHP with combined technologies of corn cobs gasification and gas turbines

    Directory of Open Access Journals (Sweden)

    Guteša Milana M.

    2016-01-01

    Full Text Available This paper presents the performance and economic analysis of the gas turbine with co-firing gas from corn cob gasification and natural gas. Adiabatic and non-adiabatic expansion in the turbine is considered. The analysis is performed parametrically with corn cob gasification gas and natural gas ratio. The volumetric energy content of fuels with different share of gas from the corn cob gasification therefore, with different calorific values, is compared by means of the Wobbe Index. In energy and economic analyses, the following configurations are dealt with: single manifold, dual manifold and separate gas systems. [Projekat Ministarstva nauke Republike Srbije, br. 33049: The Development of CHP Demonstration Plant with Biomass Gasification

  4. A microeconomic analysis of decentralized small scale biomass based CHP plants—The case of Germany

    International Nuclear Information System (INIS)

    Alternative energy sources, such as biomass CHP plants, have recently gained significantly in importance and action is due both on the large scale corporate level and on the small scale. Hence, making the scope and economic outline of such projects easily intelligible without losing relevant details seems a key factor to further promote the necessary developments. The model setup presented in this paper may therefore serve as a starting point for generating numerical results based on real life cases or scenarios. Its focus lies on the economic analysis of decentralized biomass CHP plants. It presents a new approach to analyzing the economic aspects of biomass CHP plants implementing a formal microeconomic approach. As Germany claims a leading role in the market for renewable energy production, the paper also takes a closer look on the effects of German energy policy with respect to biomass CHP plants. - Highlights: • A formal microeconomic model is used to analyse a decentralized biomass CHP plant. • Model setup is used to generate numerical results based on real life scenarios. • Nested CES production function is a new approach to model economics of biomass CHP. • Analysis presents insight into microeconomics and cost drivers of biomass CHP. • Evaluation of energy policy design with respect to environmental policy goals

  5. The Chp1-Tas3 core is a multifunctional platform critical for gene silencing by RITS

    OpenAIRE

    Schalch, Thomas; Job, Godwin; Shanker, Sreenath; Partridge, Janet F.; Joshua-Tor, Leemor

    2011-01-01

    RNA interference (RNAi) is critical for the assembly of heterochromatin at fission yeast centromeres. Central to this process is the RNA-induced Initiation of Transcriptional gene Silencing (RITS) complex, which physically anchors small non-coding RNAs to chromatin. RITS includes Ago1, the chromodomain protein Chp1, and Tas3, which bridges between Chp1 and Ago1. Chp1 is a large protein with, apart from its chromodomain, no recognizable domains. Here we describe how the structured C-terminal h...

  6. Fuel cell system with interconnect

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Zhien; Goettler, Richard; Delaforce, Philip Mark

    2016-03-08

    The present invention includes a fuel cell system having an interconnect that reduces or eliminates diffusion (leakage) of fuel and oxidant by providing an increased densification, by forming the interconnect as a ceramic/metal composite.

  7. Large stationary fuel cell systems: Status and dynamic requirements

    Science.gov (United States)

    Bischoff, Manfred

    Molten carbonate fuel cell demonstrations to-date, have been able to show the highest fuel-to-electricity conversion efficiencies (>50%) of any stand-alone fuel cell type. The primary developer of this type of fuel cell in United States is Fuel Cell Energy Corporation (FCE), the developer and manufacturer of the Direct FuelCell ™ concept. FCE and MTU CFC Solutions in Germany, a licensee of FCE have demonstrated carbonate fuel cells from 10 kW to 2 MW of electrical output on a variety of fuels. IHI in Japan are also developing carbonate fuel cells for stationary power and have recently successfully demonstrated the technology in Kawagoe, Japan. In Italy, Ansaldo fuel cell have demonstrated a 100 kW carbonate fuel cell in Milan. In Korea, the Ministry of Commerce, Industry and Energy has committed to install 300 fuel cell units, sized 250 kW to 1 MW, for distributed power generation by 2012. Carbonate fuel cell technology is more fuel flexible than lower temperature fuel cell technologies and is well suited for on-site stationary CHP applications as well as to marine, military, and traction applications. The present paper gives an overview about the commercialisation efforts for the molten carbonate fuel cell technology.

  8. Numerical optimization and economic analysis in the design of a micro-CHP systemwith a Stirling engine and a solar collector

    OpenAIRE

    Ferreira, Ana C. M.

    2014-01-01

    Tese de doutoramento do Programa Doutoral em Engenharia Industrial e de Sistemas The micro-CHP systems are a promising technology for improving the energy efficiency of small energy conversion units, located near the end user. The combined heat and power production allows the optimal use of the primary energy sources and significant reductions in carbon emissions. Its use, still incipient, has a great potential for applications in the residential sector. This study aims to develop a method...

  9. Unitized regenerative fuel cell system

    Science.gov (United States)

    Burke, Kenneth A. (Inventor)

    2008-01-01

    A Unitized Regenerative Fuel Cell system uses heat pipes to convey waste heat from the fuel cell stack to the reactant storage tanks. The storage tanks act as heat sinks/sources and as passive radiators of the waste heat from the fuel cell stack. During charge up, i.e., the electrolytic process, gases are conveyed to the reactant storage tanks by way of tubes that include dryers. Reactant gases moving through the dryers give up energy to the cold tanks, causing water vapor in with the gases to condense and freeze on the internal surfaces of the dryer. During operation in its fuel cell mode, the heat pipes convey waste heat from the fuel cell stack to the respective reactant storage tanks, thereby heating them such that the reactant gases, as they pass though the respective dryers on their way to the fuel cell stacks retrieve the water previously removed.

  10. Initial Market Assessment for Small-Scale Biomass-Based CHP

    Energy Technology Data Exchange (ETDEWEB)

    Brown, E.; Mann, M.

    2008-01-01

    The purpose of this report is to reexamine the energy generation market opportunities for biomass CHP applications smaller than 20 MW. This paper provides an overview of the benefits of and challenges for biomass CHP in terms of policy, including a discussion of the drivers behind, and constraints on, the biomass CHP market. The report provides a summary discussion of the available biomass supply types and technologies that could be used to feed the market. Two primary markets are outlined--rural/agricultural and urban--for small-scale biomass CHP, and illustrate the primary intersections of supply and demand for those markets. The paper concludes by summarizing the potential markets and suggests next steps for identifying and utilizing small-scale biomass.

  11. Optimal designs of small CHP plants in a market with fluctuating electricity prices

    DEFF Research Database (Denmark)

    Lund, Henrik; Andersen, A.N.

    2005-01-01

    The paper presents the Danish experince with methodologies and software tools, which have been used to design investment and operation strategies for almost all small CHP plants in Denmark during the decade of the triple tariff.......The paper presents the Danish experince with methodologies and software tools, which have been used to design investment and operation strategies for almost all small CHP plants in Denmark during the decade of the triple tariff....

  12. Support schemes and ownership structures - The policy context for fuel cell based micro-combined heat and power

    Energy Technology Data Exchange (ETDEWEB)

    Ropenus, S.; Thorsten Schroeder, S.; Costa, A.; Obe, E.

    2010-05-15

    In recent years, fuel cell based micro-combined heat and power has received increasing attention due to its potential contribution to energy savings, efficiency gains, customer proximity and flexibility in operation and capacity size. The FC4Home project assesses technical and economic aspects of the ongoing fuel cell based micro-combined heat and power (mCHP) demonstration projects by addressing the socio-economic and systems analyses perspectives of a large-scale promotion scheme of fuel cells. This document constitutes the deliverable of Work Package 1 of the FC4Home project and provides an introduction to the policy context for mCHP. Section 1 describes the rationale for the promotion of mCHP by explaining its potential contribution to European energy policy goals. Section 2 addresses the policy context at the supranational European level by outlining relevant EU Directives on support schemes for promoting combined heat and power and energy from renewable sources. These Directives are to be implemented at the national level by the Member States. Section 3 conceptually presents the spectrum of national support schemes, ranging from investment support to market-based operational support. The choice of support scheme simultaneously affects risk and technological development, which is the focus of Section 4. Subsequent to this conceptual overview, Section 5 takes a glance at the national application of support schemes for mCHP in practice, notably in the three country cases of the FC4Home project, Denmark, France and Portugal. Another crucial aspect for the diffusion of the mCHP technology is possible ownership structures. These may range from full consumer ownership to ownership by utilities and energy service companies, which is discussed in Section 6. Finally, a conclusion (Section 7) wraps up previous findings and provides a short 'preview' of the quantitative analyses in subsequent Work Packages by giving some food for thought on the way. (author)

  13. Antibody responses against NY-ESO-1 and HER2 antigens in patients vaccinated with combinations of cholesteryl pullulan (CHP)-NY-ESO-1 and CHP-HER2 with OK-432.

    Science.gov (United States)

    Aoki, Masatoshi; Ueda, Shugo; Nishikawa, Hiroyoshi; Kitano, Shigehisa; Hirayama, Michiko; Ikeda, Hiroaki; Toyoda, Hideki; Tanaka, Kyosuke; Kanai, Michiyuki; Takabayashi, Arimichi; Imai, Hiroshi; Shiraishi, Taizo; Sato, Eiichi; Wada, Hisashi; Nakayama, Eiichi; Takei, Yoshiyuki; Katayama, Naoyuki; Shiku, Hiroshi; Kageyama, Shinichi

    2009-11-16

    Combination vaccines of the NY-ESO-1 protein complexed with cholesteryl pullulan (CHP), CHP-NY-ESO-1, and the truncated 146HER2 protein with CHP, CHP-HER2, were subcutaneously administered with the immuno-adjuvant OK-432 to eight esophageal cancer patients. Vaccination was well-tolerated. NY-ESO-1- and HER2-specific antibody responses were analyzed using the patients' sera and samples from previous single CHP-NY-ESO-1 or CHP-HER2 vaccine trial. The responses to NY-ESO-1 in the combination vaccine study were comparable to the single vaccine. For responses to HER2, there were fewer antibody responses in the combination vaccines. Although there were marked individual variations in the antibody responses to the NY-ESO-1 and HER2 antigens, the reaction patterns to these antigens were comparable within each patient. Antibodies to OK-432 were not augmented. Protein cancer vaccines targeting multiple antigens are feasible.

  14. Wood-fired fuel cells in selected buildings

    Science.gov (United States)

    McIlveen-Wright, D. R.; McMullan, J. T.; Guiney, D. J.

    The positive attributes of fuel cells for high efficiency power generation at any scale and of biomass as a renewable energy source which is not intermittent, location-dependent or very difficult to store, suggest that a combined heat and power (CHP) system consisting of a fuel cell integrated with a wood gasifier (FCIWG) may offer a combination for delivering heat and electricity cleanly and efficiently. Phosphoric acid fuel cell (PAFC) systems, fuelled by natural gas, have already been used in a range of CHP applications in urban settings. Some of these applications are examined here using integrated biomass gasification/fuel cell systems in CHP configurations. Five building systems, which have different energy demand profiles, are assessed. These are a hospital, a hotel, a leisure centre, a multi-residential community and a university hall of residence. Heat and electricity use profiles for typical examples of these buildings were obtained and the FCIWG system was scaled to the power demand. The FCIWG system was modelled for two different types of fuel cell, the molten carbonate and the phosphoric acid. In each case an oxygen-fired gasification system is proposed, in order to eliminate the need for a methane reformer. Technical, environmental and economic analyses of each version were made, using the ECLIPSE process simulation package. Since fuel cell lifetimes are not yet precisely known, economics for a range of fuel cell lifetimes have been produced. The wood-fired PAFC system was found to have low electrical efficiency (13-16%), but much of the heat could be recovered, so that the overall efficiency was 64-67%, suitable where high heat/electricity values are required. The wood-fired molten carbonate fuel cell (MCFC) system was found to be quite efficient for electricity generation (24-27%), with an overall energy efficiency of 60-63%. The expected capital costs of both systems would currently make them uncompetitive for general use, but the specific features

  15. Crystal structure of CHP2 complexed with NHE1-cytosolic region and an implication for pH regulation

    OpenAIRE

    Ammar, Youssef Ben; Takeda, Soichi; Hisamitsu, Takashi; Mori, Hidezo; Wakabayashi, Shigeo

    2006-01-01

    The plasma membrane Na+/H+ exchangers (NHE) require calcineurin B homologous protein (CHP) as an obligatory binding partner for ion transport. Here, we report the first crystal structure of CHP (CHP2 isoform) in complex with its binding domain in NHE1. We show that the cytoplasmic α-helix of NHE1 is inserted into the hydrophobic cleft formed by N- and C-lobes of CHP2 and that the size and shape of this crevice together with hydrogen bond formation at multiple positions assure a high degree of...

  16. Thermodynamic, ecological and economic aspects of the use of the gas turbine for heat supply to the stripping process in a supercritical CHP plant integrated with a carbon capture installation

    International Nuclear Information System (INIS)

    Highlights: • Variants of integration of CHP plant with CCS and gas turbine unit were analyzed. • The simulations of operation of plants under changing load were realized. • Conditions of competitiveness for all solutions were identified. • Integration can be profitable if prices of allowance will reach values >60 €/MgCO2. - Abstract: This paper presents the results of thermodynamic and economic analyses for eight variants of a combined heat and power (CHP) plant fuelled with coal working under supercritical steam parameters and integrated with a CO2 capture installation and a gas turbine system. The motivation behind using a gas turbine in the system was to generate steam to supply heat for the stripping process that occurs in the separation installation to regenerate the sorbent. Additional analyses were conducted for the reference case, a CHP unit in which the CO2 separation process was not conducted, to enable an economic evaluation of the integration of a CHP unit with a CO2 separation installation according to the variants proposed. The break-even price of electricity and avoided emission costs were used to evaluate the respective solutions. In this paper, the results of the sensitivity analysis of the economic evaluation indicators in terms of the change in the annual operation time, price of emission allowance and heat demand rate for the realization of the stripping process for all cases are presented

  17. Development of Dendritic Cell System

    Institute of Scientific and Technical Information of China (English)

    Li Wu; Aleksandar Dakic

    2004-01-01

    The dendritic cell system contains conventional dendritic cells (DCs) and plasmacytoid pre-dendritic cells (pDCs). Both DCs and pDCs are bone marrow derived cells. Although the common functions of DCs are antigen-processing and T-lymphocyte activation, they differ in surface markers, migratory patterns, and cytokine output. These differences can determine the fate of the T cells they activate. Several subsets of mature DCs have been described in both mouse and human and the developmental processes of these specialized DC subsets have been studied extensively. The original concept that all DCs were of myeloid origin was questioned by several recent studies, which demonstrated that in addition to the DCs derived from myeloid precursors,some DCs could also be efficiently generated from lymphoid-restricted precursors. Moreover, it has been shown recently that both conventional DCs and pDCs can be generated by the Flt3 expressing hemopoietic progenitors regardless of their myeloid- or lymphoid-origin. These findings suggest an early developmental flexibility of precursors for DCs and pDCs. This review summarizes some recent observations on the development of DC system in both human and mouse.

  18. Development of Dendritic Cell System

    Institute of Scientific and Technical Information of China (English)

    LiWu; AleksandarDakic

    2004-01-01

    The dendritic cell system contains conventional dendritic cells (DCs) and plasmacytoid pre-dendritic cells (pDCs). Both DCs and pDCs are bone marrow derived calls. Although the common functions of DCs are antigen-processing and T-lymphocyte activation, they differ in surface markers, migratory patterns, and cytokine output. These differences can determine the fate of the T cells they activate. Several subsets of mature DCs have been described in both mouse and human and the developmental processes of these specialized DC subsets have been studied extensively. The original concept that all DCs were of myeloid origin was questioned by several recent studies, which demonstrated that in addition to the DCs derived from myeloid precursors, some DCs could also be efficiently generated from lymphoid-restricted precursors. Moreover, it has been shown recently that both conventional DCs and pDCs can be generated by the Fit3 expressing hemopoietic progenitors regardless of their myeloid- or lymphoid-origin. These findings suggest an early developmental flexibility of precursors for DCs and pDCs. This review summarizes some recent observations on the development of DC system in both human and mouse. Cellular & Molecular Immunology. 2004;1(2):112-118.

  19. Parametric analysis of an irreversible proton exchange membrane fuel cell/absorption refrigerator hybrid system

    International Nuclear Information System (INIS)

    A hybrid system mainly consisting of a PEMFC (proton exchange membrane fuel cell) and an absorption refrigerator is proposed, where the PEMFC directly converts the chemical energy contained in the hydrogen into electrical and thermal energies, and the thermal energy is transferred to drive the bottoming absorption refrigerator for cooling purpose. By considering the existing irreversible losses in the hybrid system, the operating current density region of the PEMFC permits the absorption refrigerator to exert its function is determined and the analytical expressions for the equivalent power output and efficiency of the hybrid system under different operating conditions are specified. Numerical calculations show that the equivalent maximum power density and the corresponding efficiency of the hybrid system can be respectively increased by 5.3% and 6.8% compared to that of the stand-alone PEMFC. Comprehensive parametric analyses are conducted to reveal the effects of the internal irreversibility of the absorption refrigerator, operating current density, operating temperature and operating pressure of the PEMFC, and some integrated parameters related to the thermodynamic losses on the performance of the hybrid system. The model presented in the paper is more general than previous study, and the results for some special cases can be directly derived from this paper. - Highlights: • A CHP system composed of a PEMFC and an absorption refrigerator is proposed. • Current density region enables the absorption refrigerator to work is determined. • Multiple irreversible losses in the system are analytically characterized. • Maximum power density and corresponding efficiency can be increased by 5.3% and 6.8%. • Effects of some designing and operating parameters on the performance are discussed

  20. Combined heat and power systems: economic and policy barriers to growth

    OpenAIRE

    Kalam Adil; King Abigail; Moret Ellen; Weerasinghe Upekha

    2012-01-01

    Abstract Background Combined Heat and Power (CHP) systems can provide a range of benefits to users with regards to efficiency, reliability, costs and environmental impact. Furthermore, increasing the amount of electricity generated by CHP systems in the United States has been identified as having significant potential for impressive economic and environmental outcomes on a national scale. Given the benefits from increasing the adoption of CHP technologies, there is value in improving our unde...

  1. Development and analysis of micro-polygeneration systems and adsorption chillers

    Science.gov (United States)

    Gluesenkamp, Kyle

    About a fifth of all primary energy in the US is consumed by residential buildings, mostly for cooling, heating and to provide electricity. Furthermore, retrofits are essential to reducing this consumption, since the buildings that exist today will comprise over half of those in use in 2050. Residential combined heat and power (or micro CHP, defined by heating season by 5-30%. This thesis investigates the addition of a thermally-driven chiller/heat pump to a CHP system (to form a trigeneration system) to additionally provide savings during the cooling season, and enhance heating season savings. Scenarios are identified in which adding thermally-driven equipment to a micro CHP system reduces primary energy consumption, through analytical and experimental investigations. The experimental focus is on adsorption heat pump systems, which are capable of being used with the CHP engines (prime movers) that are already widely deployed. The analytical analysis identifies energy saving potential off-grid for today's prime movers, with potential on-grid for various fuel cell technologies. A novel dynamic test facility was developed to measure real-world residential trigeneration system performance using a prototype adsorption chiller. The chiller was designed and constructed for this thesis and was driven by waste heat from a commercially available natural gas-fueled 4 kW (electric) CHP engine. A control strategy for the chiller was developed, enabling a 5-day experiment to be run using a thermal load profile based on moderate Maryland summer air conditioning loads and typical single-family domestic hot water demand, with experimental results in agreement with models. In this summer mode, depending on electrical loads, the trigeneration system used up to 36% less fuel than off-grid separate generation and up to 29% less fuel than off-grid CHP without thermally driven cooling. However, compared to on-grid separate generation, the experimental facility used 16% more primary

  2. Balmorel: A model for analyses of the electricity and CHP markets in the Baltic Sea Region

    International Nuclear Information System (INIS)

    This report describes the motivations behind the development of the Balmorel model as well as the model itself. The purpose of the Balmorel project is to develop a model for analyses of the power and CHP sectors in the Baltic Sea Region. The model is directed towards the analysis of relevant policy questions to the extent that they contain substantial international aspects. The model is developed in response to the trend towards internationalisation in the electricity sector. This trend is seen in increased international trade of electricity, in investment strategies among producers and otherwise. Also environmental considerations and policies are to an increasing extent gaining an international perspective in relation to the greenhouse gasses. Further, the ongoing process of deregulation of the energy sector highlights this and contributes to the need for overview and analysis. A guiding principle behind the construction of the model has been that it may serve as a means of communication in relation to the policy issues that already are or that may become important for the region. Therefore, emphasis has been put on documentation, transparency and flexibility of the model. This is achieved in part by formulating the model in a high level modelling language, and by making the model, including data, available at the internet. Potential users of the Balmorel model include research institutions, consulting companies, energy authorities, transmission system operators and energy companies. (au)

  3. Energy System Analysis of Large-Scale Integration of Wind Power

    International Nuclear Information System (INIS)

    The paper presents the results of two research projects conducted by Aalborg University and financed by the Danish Energy Research Programme. Both projects include the development of models and system analysis with focus on large-scale integration of wind power into different energy systems. Market reactions and ability to exploit exchange on the international market for electricity by locating exports in hours of high prices are included in the analyses. This paper focuses on results which are valid for energy systems in general. The paper presents the ability of different energy systems and regulation strategies to integrate wind power, The ability is expressed by three factors: One factor is the degree of electricity excess production caused by fluctuations in wind and CHP heat demands. The other factor is the ability to utilise wind power to reduce CO2 emission in the system. And the third factor is the ability to benefit from exchange of electricity on the market. Energy systems and regulation strategies are analysed in the range of a wind power input from 0 to 100% of the electricity demand. Based on the Danish energy system, in which 50 per cent of the electricity demand is produced in CHP, a number of future energy systems with CO2 reduction potentials are analysed, i.e. systems with more CHP, systems using electricity for transportation (battery or hydrogen vehicles) and systems with fuel-cell technologies. For the present and such potential future energy systems different regulation strategies have been analysed, i.e. the inclusion of small CHP plants into the regulation task of electricity balancing and grid stability and investments in electric heating, heat pumps and heat storage capacity. Also the potential of energy management has been analysed. The results of the analyses make it possible to compare short-term and long-term potentials of different strategies of large-scale integration of wind power

  4. On-line experimental validation of a model-based diagnostic algorithm dedicated to a solid oxide fuel cell system

    Science.gov (United States)

    Polverino, Pierpaolo; Esposito, Angelo; Pianese, Cesare; Ludwig, Bastian; Iwanschitz, Boris; Mai, Andreas

    2016-02-01

    In the current energetic scenario, Solid Oxide Fuel Cells (SOFCs) exhibit appealing features which make them suitable for environmental-friendly power production, especially for stationary applications. An example is represented by micro-combined heat and power (μ-CHP) generation units based on SOFC stacks, which are able to produce electric and thermal power with high efficiency and low pollutant and greenhouse gases emissions. However, the main limitations to their diffusion into the mass market consist in high maintenance and production costs and short lifetime. To improve these aspects, the current research activity focuses on the development of robust and generalizable diagnostic techniques, aimed at detecting and isolating faults within the entire system (i.e. SOFC stack and balance of plant). Coupled with appropriate recovery strategies, diagnosis can prevent undesired system shutdowns during faulty conditions, with consequent lifetime increase and maintenance costs reduction. This paper deals with the on-line experimental validation of a model-based diagnostic algorithm applied to a pre-commercial SOFC system. The proposed algorithm exploits a Fault Signature Matrix based on a Fault Tree Analysis and improved through fault simulations. The algorithm is characterized on the considered system and it is validated by means of experimental induction of faulty states in controlled conditions.

  5. Integrated Combined Heat and Power System Dispatch Considering Electrical and Thermal Energy Storage

    OpenAIRE

    Rongxiang Yuan; Jun Ye; Jiazhi Lei; Timing Li

    2016-01-01

    Wind power has achieved great development in Northern China, but abundant wind power is dissipated, rather than utilized, due to inflexible electricity production of combined heat and power (CHP) units. In this paper, an integrated CHP system consisting of CHP units, wind power plants, and condensing power plants is investigated to decouple the power and heat production on both the power supply side and heat supply side, by incorporating electrical energy storage (EES) and thermal energy stor...

  6. Battery Cell Balancing System and Method

    Science.gov (United States)

    Davies, Francis J. (Inventor)

    2014-01-01

    A battery cell balancing system is operable to utilize a relatively small number of transformers interconnected with a battery having a plurality of battery cells to selectively charge the battery cells. Windings of the transformers are simultaneously driven with a plurality of waveforms whereupon selected battery cells or groups of cells are selected and charged. A transformer drive circuit is operable to selectively vary the waveforms to thereby vary a weighted voltage associated with each of the battery cells.

  7. Effects of CHP,H2O2 and Antioxidants on Contents of NO, Carbonyl and malondialdehyde of Cultured Hepatoma Cells in Different Phases of Cell Cycle%过氧基异丙苯和H2O2及抗氧化剂对不同时相肝癌细胞的NO、羰基和丙二醛的影响

    Institute of Scientific and Technical Information of China (English)

    梁欣; 海春旭

    2007-01-01

    背景与目的:研究有机氧化剂过氧基异丙苯(CHP)和无机氧化剂过氧化氢(H2O2)及抗氧化剂单独和联合作用对不同细胞周期时相肝癌细胞的一氧化氮(NO)、羰基和丙二醛(MDA)的影响.材料与方法:同步化原发性肝癌细胞系H299细胞(1×106/ml),分别设对照组(DMSO)、CHP组(50μmol/ml)、H2O2组(50 μmol/ml)、CHP+H2O2组(H2O2和CHP各50μmol/ml)、Vit A组(10μmol/ml)、Vit E组(10μmol/ml)、Na2SeO3组(50 nmol/ml Na2SeO3)、AO组(Vit A+Vit E+Na2SeO3,其中Vit A、Vit E各5 μmol/ml,Na2SeO325 nmol/ml).分别于细胞周期G1、S、G2和M期加入上述试剂,观察NO、总羰基和MDA含量.结果:细胞同步于G1期者为86%,S期为78%、G2/M期为61%.与对照组相比,复合氧化剂(CHP+H2O2组)对G1期肝癌细胞的NO含量有刺激作用(P<0.05),单独Vit A组有显著的抑制作用(P<0.05).复合氧化剂(CHP+H2O2组)对G1~M期肝癌细胞的总羰基含量均有显著的刺激作用(P<0.05),而单独应用Vit A、Vit E、Na2SeO3时对整个细胞周期的总羰基含量也有显著的抑制作用(P<0.05).H2O2使G2/M期细胞的MDA含量增加(P<0.05),而AO组MDA含量减少(P<0.05).结论:细胞经同步化处理后,CHP和H2O2以及Vit A、Vit E、Na2SeO3对肿瘤细胞的影响存在一定的敏感点和敏感时相,复合氧化剂(CHP+H2O2)和Vit A对DNA合成前期(G1期)肿瘤细胞内的氧化损伤信号分子NO作用显著;H2O2与复合抗氧化剂(Vit A+Vit E+Na2SeO3)作用于DNA合成后期(G2期)的肿瘤细胞后,细胞氧化损伤的终产物MDA明显改变.

  8. A Compound Herbal Preparation (CHP) in the Treatment of Children with ADHD: A Randomized Controlled Trial

    Science.gov (United States)

    Katz, M.; Adar Levine, A.; Kol-Degani, H.; Kav-Venaki, L.

    2010-01-01

    Objective: Evaluation of the efficacy of a patented, compound herbal preparation (CHP) in improving attention, cognition, and impulse control in children with ADHD. Method: Design: A randomized, double-blind, placebo-controlled trial. Setting: University-affiliated tertiary medical center. Participants: 120 children newly diagnosed with ADHD,…

  9. Investigation of Continuous Gas Engine CHP Operation on Biomass Producer Gas

    DEFF Research Database (Denmark)

    Ahrenfeldt, Jesper; Henriksen, Ulrik Birk; Jensen, Torben Kvist;

    2005-01-01

    More than 2000 hours of gas engine operation with producer gas from biomass as fuel has been conducted on the gasification CHP demonstration and research plant, named “Viking” at the Technical University of Denmark. The gas engine is an integrated part of the entire gasification plant. The excess...

  10. EFFICIENCY OF THE USE OF HEAT PUMPS ON THE CHP PLANTS

    Directory of Open Access Journals (Sweden)

    Juravleov A.A.

    2007-04-01

    Full Text Available The work is dedicated to the calculus of the efficiency of the use of heat pumps on the CHP plants. There are presented the interdependences between the pay-back period and NPV of heat pump and the price of 1 kWt of thermal power of heat pump and of the tariff of electricity.

  11. Modular PEM Fuel Cell SCADA & Simulator System

    Directory of Open Access Journals (Sweden)

    Francisca Segura

    2015-09-01

    Full Text Available The paper presents a Supervision, Control, Data Acquisition and Simulation (SCADA & Simulator system that allows for real-time training in the actual operation of a modular PEM fuel cell system. This SCADA & Simulator system consists of a free software tool that operates in real time and simulates real situations like failures and breakdowns in the system. This developed SCADA & Simulator system allows us to properly operate a fuel cell and helps us to understand how fuel cells operate and what devices are needed to configure and run the fuel cells, from the individual stack up to the whole fuel cell system. The SCADA & Simulator system governs a modular system integrated by three PEM fuel cells achieving power rates higher than tens of kilowatts.

  12. A comparison between the two different combustion methods of Grate-firing and Fluidized bed, applied to a CHP-plant with MSW as fuel

    OpenAIRE

    Hasan, Belkiz; Ahsant, Aidin

    2015-01-01

    In this study, the two most frequently used incineration systems, fluidized bed and grate-firing have been compared and analyzed. The performance of Mälarenergi’s combined heat and power (CHP) plant in Västerås, which consists of a fluidized bed incinerator, has been used as benchmark to elaborate the different calculations made in this study. It extracts electricity and heat amounting to 50 and 100 MW respectively.   On average, 75-85% of the weight of Municipal Solid Waste (MSW) is converte...

  13. System Studies of Fuel Cell Power Plants

    OpenAIRE

    Kivisaari, Timo

    2001-01-01

    This thesis concerns system studies of power plants wheredifferent types of fuel cells accomplish most of the energyconversion. Ever since William Grove observed the fuel cell effect inthe late 1830s fuel cells have been the subject or more or lessintense research and development. Especially in the USA theseactivities intensified during the second part of the 1950s,resulting in the development of the fuel cells used in theApollo-program. Swedish fuel cell activities started in themid-1960s, w...

  14. Investigations on an advanced power system based on a high temperature polymer electrolyte membrane fuel cell and an organic Rankine cycle for heating and power production

    International Nuclear Information System (INIS)

    Energy systems based on fuel cells technology can have a strategic role in the range of small-size power generation for the sustainable energy development. In order to enhance their performance, it is possible to recover the “waste heat” from the fuel cells, for producing or thermal power (cogeneration systems) or further electric power by means of a bottoming power cycle (combined systems). In this work an advanced system based on the integration between a HT-PEMFC (high temperature polymer electrolyte membrane fuel cell) power unit and an ORC (organic Rankine cycle) plant, has been proposed and analysed as suitable energy power plant for supplying electric and thermal energies to a stand-alone residential utility. The system can operate both as cogeneration system, in which the electric and thermal loads are satisfied by the HT-PEMFC power unit and as electric generation system, in which the low temperature heat recovered from the fuel cells is used as energy source in the ORC plant for increasing the electric power production. A numerical model, able to characterize the behavior and to predict the performance of the HT-PEMFC/ORC system under different working conditions, has been developed by using the AspenPlus™ code. - Highlights: • The advanced plant can operate both as CHP system and as electric generation system. • The performance prediction of the integrated system is carried out by numerical modeling. • ORC thermodynamic optimization is carried out by a sensitivity analysis. • Thermal coupling between the HT-PEMC system and the ORC plant is analyzed. • Results are very promising in the field of the distributed generation

  15. Opportunity and potential for fuel cell systems for energy in buildings; Moejlighet och potential foer braenslecellsystem foer energifoersoerjning i byggnader

    Energy Technology Data Exchange (ETDEWEB)

    Jannasch, Anna-Karin (Catator AB (Sweden))

    2011-04-15

    While planning for new sustainable and environmentally friendly communities in Sweden, discussions on using fuel cells for small-scale power and heat production (mCHP) are today on-going. Examples of such communities are Sege Park in Malmoe and Norra Djurgardsstaden in Stockholm, where several members of the Swedish Construction Industry's Organisation for Research and Development (SBUF) are participating in the development. The status and the potential of using fuel cell based mCHP compared to conventional heat and power production technology and other mCHP-technologies (Internal combustion engine (ICE), Stirling) is today therefore a very interesting question for both the energy and the building sector, who also ask for more knowledge within the field. This work focuses on this purpose. The main goals of this report are: 1. To give an overall description of different existing fuel cell technologies and necessary belonging system components. The fuel cell systems are discussed and evaluated based on parameters such as efficiencies, fuel flexibility, life-time, complexity, maturity and cost. The systems are compared to mCHPs based on small heat engines (Internal combustion, Stirling). 2. To give a state-of-the-art report on fuel cell based mCHPs and to describe possibilities and risks related to different technologies. 3. To guideline for future choices of system solutions suitable for different building constructions and different geographical placements. The work is limited to systems suitable for small houses (< 5 kWe) and larger residential buildings (< 50 kWe) situated in population centres/cities where infra-structures for natural gas/biogas and the national grid are available. The project has been performed by Catator AB on the request of SBUF with support from the Swedish Gas Centre (SGC AB), Skanska and Catator. The study is based on the open literature, the information given by leading fuel cell system suppliers and Catator's own knowledge and

  16. Effects of fuel processing methods on industrial scale biogas-fuelled solid oxide fuel cell system for operating in wastewater treatment plants

    Science.gov (United States)

    Farhad, Siamak; Yoo, Yeong; Hamdullahpur, Feridun

    The performance of three solid oxide fuel cell (SOFC) systems, fuelled by biogas produced through anaerobic digestion (AD) process, for heat and electricity generation in wastewater treatment plants (WWTPs) is studied. Each system has a different fuel processing method to prevent carbon deposition over the anode catalyst under biogas fuelling. Anode gas recirculation (AGR), steam reforming (SR), and partial oxidation (POX) are the methods employed in systems I-III, respectively. A planar SOFC stack used in these systems is based on the anode-supported cells with Ni-YSZ anode, YSZ electrolyte and YSZ-LSM cathode, operated at 800 °C. A computer code has been developed for the simulation of the planar SOFC in cell, stack and system levels and applied for the performance prediction of the SOFC systems. The key operational parameters affecting the performance of the SOFC systems are identified. The effect of these parameters on the electrical and CHP efficiencies, the generated electricity and heat, the total exergy destruction, and the number of cells in SOFC stack of the systems are studied. The results show that among the SOFC systems investigated in this study, the AGR and SR fuel processor-based systems with electrical efficiency of 45.1% and 43%, respectively, are suitable to be applied in WWTPs. If the entire biogas produced in a WWTP is used in the AGR or SR fuel processor-based SOFC system, the electricity and heat required to operate the WWTP can be completely self-supplied and the extra electricity generated can be sold to the electrical grid.

  17. Life cycle assessment of micro production technologies - solar cells, household wind turbines and micro motors; Livscyklusvurdering af mikroproduktionsteknologier - solceller, husstandsvindmoeller og mikromotorer

    Energy Technology Data Exchange (ETDEWEB)

    Faeborg Poulsen, A.; Kruse, H.; Hvid Ipsen, K.

    2000-07-15

    This report contains a life cycle based estimation of environmental effects of CHP based on the micro production technologies: solar cells, household wind turbines and micro motors. The technologies cover CHP production on very small plants which are characterised by being located by the individual consumer. (BA)

  18. Innovative High Temperature Fuel Cell systems

    NARCIS (Netherlands)

    Au, Siu Fai

    2003-01-01

    The world's energy consumption is growing extremely rapidly. Fuel cell systems are of interest by researchers and industry as the more efficient alternative to conventional thermal systems for power generation. The principle of fuel cell conversion does not involve thermal combustion and hence in th

  19. Operating Experiences with a Small-scale CHP Pilot Plant based on a 35 kWel Hermetic Four Cylinder Stirling Engine for Biomass Fuels

    DEFF Research Database (Denmark)

    Biedermann, F.; Carlsen, Henrik; Schoech, M.;

    2003-01-01

    Within the scope of the RD&D project presented a small-scale CHP plant with a hermetic four cylinder Stirling engine for biomass fuels was developed and optimised in cooperation with the Technical University of Denmark, MAWERA Holzfeuerungsanlagen GesmbH, an Austrian biomass furnace and boiler ma...... exchanger of the Stirling engine, of the air preheater and of the entire combustion system. Furthermore, the optimisation of the pneumatic cleaning system to reduce ash deposition in the hot heat exchanger is of great relevance.......Within the scope of the RD&D project presented a small-scale CHP plant with a hermetic four cylinder Stirling engine for biomass fuels was developed and optimised in cooperation with the Technical University of Denmark, MAWERA Holzfeuerungsanlagen GesmbH, an Austrian biomass furnace and boiler...... manufacturer, and BIOS BIOENERGIESYSTEME GmbH, an Austrian development and engineering company. Based on the technology developed, a pilot plant was designed and erected in Austria. The nominal electric power output of the plant is 35 kWel and the nominal thermal output amounts to approx. 220 kWth. The plant...

  20. Development of HT-PEMFC components and stack for CHP unit

    Energy Technology Data Exchange (ETDEWEB)

    Jensen, Jens Oluf; Li, Q. (Technical Univ. of Denmark, Dept. of Chemistry, Kgs. Lyngby (Denmark)); Terkelsen, C.; Rudbech, H.C.; Steenberg, T. (Danish Power System Aps, Charlottenlund (Denmark)); Thibault de Rycke (IRD Fuel Cell A/S, Svendborg (Denmark))

    2009-10-15

    The aim of the project has been to further develop components for an all Danish high temperature PEM fuel cells stack for application in combined heat and power units (CHP units). The final product aimed at was a 1.5-2 kW stack for operation at 150-200 deg. C. The project follows the previous PSO project 4760, 'High Temperature PEM Fuel Cell'. The project has addressed the HT-PEM fuel cells form a components point of view and the materials here for. The main areas were polymer and membrane development, electrode and MEA development (MEA = membrane electrode assembly, i.e. the cells.) and stack development. The membrane development begins with the polymer. The polymerization technique was improved significantly in two ways. Better understanding of the process and the critical issues has led to more reproducible results with repeated high molecular weights. The molecular weight is decisive for the membrane strength and durability. The process was also scaled up to 100-200 g polymer pr. batch in a new polymerization facility build during the project. It is dimensioned for larger batches too, but this was not verified during the project. The polymer cannot be purchased in the right quality for fuel cell membranes and it is important that it manufacture is not a limiting factor at the present state. Experiments with other membrane casting techniques were also made. The traditional PBI doped with phosphoric acid is still the state of art membrane for the HT-PEM fuel cells, but progress was also made with modified membranes. Different variants of PBI were synthesized and tested. Electrodes have been manufactured by a spray technique in contrast to the previously applied tape casting. The hand held spray gun previously led to an improvement of the electrodes, but the reproducibility was limited. Subsequently the construction of a semi automated spray machine was started and results like of the best hand sprayed electrodes were obtained. A viable way of MEA rim

  1. ASSESSMENT OF COMBINED HEAT AND POWER SYSTEM"PREMIUM POWER" APPLICATIONS IN CALIFORNIA

    Energy Technology Data Exchange (ETDEWEB)

    Norwood, Zack; Lipman, Timothy; Stadler, Michael; Marnay, Chris

    2010-06-01

    The effectiveness of combined heat and power (CHP) systems for power interruption intolerant,"premium power," facilities is the focus of this study. Through three real-world case studies and economic cost minimization modeling, the economic and environmental performance of"premium power" CHP is analyzed. The results of the analysis for a brewery, data center, and hospital lead to some interesting conclusions about CHP limited to the specific CHP technologies installed at those sites. Firstly, facilities with high heating loads prove to be the most appropriate for CHP installations from a purely economic standpoint. Secondly, waste heat driven thermal cooling systems are only economically attractive if the technology for these chillers can increase above the current best system efficiency. Thirdly, if the reliability of CHP systems proves to be as high as diesel generators they could replace these generators at little or no additional cost if the thermal to electric (relative) load of those facilities was already high enough to economically justify a CHP system. Lastly, in terms of greenhouse gas emissions, the modeled CHP systems provide some degree of decreased emissions, estimated at approximately 10percent for the hospital, the application with the highest relative thermal load in this case

  2. Water reactive hydrogen fuel cell power system

    Science.gov (United States)

    Wallace, Andrew P; Melack, John M; Lefenfeld, Michael

    2014-01-21

    A water reactive hydrogen fueled power system includes devices and methods to combine reactant fuel materials and aqueous solutions to generate hydrogen. The generated hydrogen is converted in a fuel cell to provide electricity. The water reactive hydrogen fueled power system includes a fuel cell, a water feed tray, and a fuel cartridge to generate power for portable power electronics. The removable fuel cartridge is encompassed by the water feed tray and fuel cell. The water feed tray is refillable with water by a user. The water is then transferred from the water feed tray into a fuel cartridge to generate hydrogen for the fuel cell which then produces power for the user.

  3. Dicty_cDB: CHP695 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 923 |AX251923.1 Sequence 184 from Patent WO0168911. 32 0.030 5 BD460387 |BD460387.1 Diagnosis of Diseases Associated with Cell Cycle.... 32 0.030 5 BD452309 |BD452309.1 Diagnosis of Diseases Associated with Cell Cycle.

  4. Robust Management of Combined Heat and Power Systems via Linear Decision Rules

    DEFF Research Database (Denmark)

    Zugno, Marco; Morales González, Juan Miguel; Madsen, Henrik

    2014-01-01

    and in the electricity prices that owners of CHP units receive for the power they sell in the market. In this work, we model the management problem for a coupled heat-and-power system comprising CHP plants, units solely producing heat as well as heat storages. We propose a robust optimization model including unit...

  5. Optical cell monitoring system for underwater targets

    Science.gov (United States)

    Moon, SangJun; Manzur, Fahim; Manzur, Tariq; Demirci, Utkan

    2008-10-01

    We demonstrate a cell based detection system that could be used for monitoring an underwater target volume and environment using a microfluidic chip and charge-coupled-device (CCD). This technique allows us to capture specific cells and enumerate these cells on a large area on a microchip. The microfluidic chip and a lens-less imaging platform were then merged to monitor cell populations and morphologies as a system that may find use in distributed sensor networks. The chip, featuring surface chemistry and automatic cell imaging, was fabricated from a cover glass slide, double sided adhesive film and a transparent Polymethlymetacrylate (PMMA) slab. The optically clear chip allows detecting cells with a CCD sensor. These chips were fabricated with a laser cutter without the use of photolithography. We utilized CD4+ cells that are captured on the floor of a microfluidic chip due to the ability to address specific target cells using antibody-antigen binding. Captured CD4+ cells were imaged with a fluorescence microscope to verify the chip specificity and efficiency. We achieved 70.2 +/- 6.5% capturing efficiency and 88.8 +/- 5.4% specificity for CD4+ T lymphocytes (n = 9 devices). Bright field images of the captured cells in the 24 mm × 4 mm × 50 μm microfluidic chip were obtained with the CCD sensor in one second. We achieved an inexpensive system that rapidly captures cells and images them using a lens-less CCD system. This microfluidic device can be modified for use in single cell detection utilizing a cheap light-emitting diode (LED) chip instead of a wide range CCD system.

  6. An Automatic Indirect Immunofluorescence Cell Segmentation System

    Directory of Open Access Journals (Sweden)

    Yung-Kuan Chan

    2014-01-01

    Full Text Available Indirect immunofluorescence (IIF with HEp-2 cells has been used for the detection of antinuclear autoantibodies (ANA in systemic autoimmune diseases. The ANA testing allows us to scan a broad range of autoantibody entities and to describe them by distinct fluorescence patterns. Automatic inspection for fluorescence patterns in an IIF image can assist physicians, without relevant experience, in making correct diagnosis. How to segment the cells from an IIF image is essential in developing an automatic inspection system for ANA testing. This paper focuses on the cell detection and segmentation; an efficient method is proposed for automatically detecting the cells with fluorescence pattern in an IIF image. Cell culture is a process in which cells grow under control. Cell counting technology plays an important role in measuring the cell density in a culture tank. Moreover, assessing medium suitability, determining population doubling times, and monitoring cell growth in cultures all require a means of quantifying cell population. The proposed method also can be used to count the cells from an image taken under a fluorescence microscope.

  7. Branched signal wiring of an essential bacterial cell-cycle phosphotransfer protein

    OpenAIRE

    Blair, Jimmy A.; Xu, Qingping; Childers, W. Seth; Mathews, Irimpan I.; Kern, Justin W.; Eckart, Michael; Deacon, Ashley M.; Shapiro, Lucy

    2013-01-01

    Vital to bacterial survival is the faithful propagation of cellular signals, and in Caulobacter crescentus ChpT is an essential mediator within the cell cycle circuit. ChpT functions as a histidine-containing phosphotransfer protein (HPt) that shuttles a phosphoryl group from the receiver domain of CckA, the upstream hybrid histidine kinase (HK), to one of two downstream response regulators (RRs)—CtrA or CpdR—that controls cell cycle progression. To understand how ChpT interacts with multiple...

  8. Modeling of a thermally integrated 10 kWe planar solid oxide fuel cell system with anode offgas recycling and internal reforming by discretization in flow direction

    Science.gov (United States)

    Wahl, Stefanie; Segarra, Ana Gallet; Horstmann, Peter; Carré, Maxime; Bessler, Wolfgang G.; Lapicque, François; Friedrich, K. Andreas

    2015-04-01

    Combined heat and power production (CHP) based on solid oxide fuel cells (SOFC) is a very promising technology to achieve high electrical efficiency to cover power demand by decentralized production. This paper presents a dynamic quasi 2D model of an SOFC system which consists of stack and balance of plant and includes thermal coupling between the single components. The model is implemented in Modelica® and validated with experimental data for the stack UI-characteristic and the thermal behavior. The good agreement between experimental and simulation results demonstrates the validity of the model. Different operating conditions and system configurations are tested, increasing the net electrical efficiency to 57% by implementing an anode offgas recycle rate of 65%. A sensitivity analysis of characteristic values of the system like fuel utilization, oxygen-to-carbon ratio and electrical efficiency for different natural gas compositions is carried out. The result shows that a control strategy adapted to variable natural gas composition and its energy content should be developed in order to optimize the operation of the system.

  9. Techno-economic performance analysis of bio-oil based Fischer-Tropsch and CHP synthesis platform

    International Nuclear Information System (INIS)

    The techno-economic potential of the UK poplar wood and imported oil palm empty fruit bunch derived bio-oil integrated gasification and Fischer-Tropsch (BOIG-FT) systems for the generation of transportation fuels and combined heat and power (CHP) was investigated. The bio-oil was represented in terms of main chemical constituents, i.e. acetic acid, acetol and guaiacol. The compositional model of bio-oil was validated based on its performance through a gasification process. Given the availability of large scale gasification and FT technologies and logistic constraints in transporting biomass in large quantities, distributed bio-oil generations using biomass pyrolysis and centralised bio-oil processing in BOIG-FT system are technically more feasible. Heat integration heuristics and composite curve analysis were employed for once-through and full conversion configurations, and for a range of economies of scale, 1 MW, 675 MW and 1350 MW LHV of bio-oil. The economic competitiveness increases with increasing scale. A cost of production of FT liquids of 78.7 Euro/MWh was obtained based on 80.12 Euro/MWh of electricity, 75 Euro/t of bio-oil and 116.3 million Euro/y of annualised capital cost. -- Highlights: → Biomass to liquid process and gas to liquid process synthesis. → Biorefinery economic analysis. → Pyrolysis oil to biofuel. → Gasification and Fischer-Tropsch. → Process integration, pinch analysis and energy efficiency.

  10. Direct methanol feed fuel cell and system

    Science.gov (United States)

    Surampudi, Subbarao (Inventor); Frank, Harvey A. (Inventor); Narayanan, Sekharipuram R. (Inventor); Chun, William (Inventor); Jeffries-Nakamura, Barbara (Inventor); Kindler, Andrew (Inventor); Halpert, Gerald (Inventor)

    2009-01-01

    Improvements to non acid methanol fuel cells include new formulations for materials. The platinum and ruthenium are more exactly mixed together. Different materials are substituted for these materials. The backing material for the fuel cell electrode is specially treated to improve its characteristics. A special sputtered electrode is formed which is extremely porous. The fuel cell system also comprises a fuel supplying part including a meter which meters an amount of fuel which is used by the fuel cell, and controls the supply of fuel based on said metering.

  11. Regenerative fuel cell systems R and D

    Energy Technology Data Exchange (ETDEWEB)

    Mitlitsky, F.; Myers, B.; Weisberg, A.H. [Lawrence Livermore National Lab., Livermore, CA (United States)

    1998-08-01

    Regenerative fuel cell (RFC) systems produce power and electrolytically regenerate their reactants using stacks of electrochemical cells. Energy storage systems with extremely high specific energy (> 400 Wh/kg) have been designed that use lightweight pressure vessels to contain the gases generated by reversible (unitized) regenerative fuel cells (URFCs). Progress is reported on the development, integration, and operation of rechargeable energy storage systems with such high specific energy. Lightweight pressure vessels that enable high specific energies have been designed with performance factors (burst pressure/internal volume/tank weight) > 50 km (2.0 million inches), and a vessel with performance factor of 40 km (1.6 million inches) was fabricated. New generations of both advanced and industry-supplied hydrogen tankage are under development. A primary fuel cell test rig with a single cell (46 cm{sup 2} active area) has been modified and operated reversibly as a URFC (for up to 2010 cycles on a single cell). This URFC uses bifunctional electrodes (oxidation and reduction electrodes reverse roles when switching from charge to discharge, as with a rechargeable battery) and cathode feed electrolysis (water is fed from the hydrogen side of the cell). Recent modifications also enable anode feed electrolysis (water is fed from the oxygen side of the cell). Hydrogen/halogen URFCs, capable of higher round-trip efficiency than hydrogen/oxygen URFCs, have been considered, and will be significantly heavier. Progress is reported on higher performance hydrogen/oxygen URFC operation with reduced catalyst loading.

  12. Investment in new power generation under uncertainty: Benefits of CHP vs. condensing plants in a copula-based analysis

    International Nuclear Information System (INIS)

    In this paper, we apply a spread-based real options approach to analyze the decision-making problem of an investor who has the choice between an irreversible investment in a condensing power plant without heat utilization and a plant with combined heat-and-power (CHP) generation. Our investigation focuses on large-scale fossil-fueled generation technologies and is based on a stochastic model that uses copula functions to provide the input parameters of the real options model. We define the aggregated annual spread as assessment criteria for our investigation since it contains all relevant volatile input parameters that have an impact on the evaluation of investment decisions. We show that the specific characteristics of CHP plants, such as additional revenues from heat sales, promotion schemes, specific operational features, and a beneficial allocation of CO2 allowances, have a significant impact on the option value and therefore on the optimal timing for investment. For the two fossil-fueled CHP technologies investigated (combined-cycle gas turbine and steam turbine), we conclude from our analysis that a high share of CHP generation reduces the risk exposure for the investor. The maximal possible CHP generation depends significantly on the local heat demand in the surroundings of the power plant. Considering this, the size of the heat sink available could gain more relevance in the future selection process of sites for new large-scale fossil power plants.

  13. Fuel cell power system for utility vehicle

    Energy Technology Data Exchange (ETDEWEB)

    Graham, M.; Barbir, F.; Marken, F.; Nadal, M. [Energy Partners, Inc., West Palm Beach, FL (United States)

    1996-12-31

    Based on the experience of designing and building the Green Car, a fuel cell/battery hybrid vehicle, and Genesis, a hydrogen/oxygen fuel cell powered transporter, Energy Partners has developed a fuel cell power system for propulsion of an off-road utility vehicle. A 10 kW hydrogen/air fuel cell stack has been developed as a prototype for future mass production. The main features of this stack are discussed in this paper. Design considerations and selection criteria for the main components of the vehicular fuel cell system, such as traction motor, air compressor and compressor motor, hydrogen storage and delivery, water and heat management, power conditioning, and control and monitoring subsystem are discussed in detail.

  14. The use of cationic nanogels to deliver proteins to myeloma cells and primary T lymphocytes that poorly express heparan sulfate.

    Science.gov (United States)

    Watanabe, Kozo; Tsuchiya, Yumiko; Kawaguchi, Yoshinori; Sawada, Shin-ichi; Ayame, Hirohito; Akiyoshi, Kazunari; Tsubata, Takeshi

    2011-09-01

    Fusion proteins containing protein transduction domain (PTD) are widely used for intracellular delivery of exogenous proteins. PTD-mediated delivery requires expression of heparan sulfate on the surface of the target cells. However, some of metastatic tumor cells and primary lymphocytes poorly express heparan sulfate. Here we demonstrate that proteins complexed with nanosize hydrogels formed by cationic cholesteryl group-bearing pullulans (cCHP) are efficiently delivered to myeloma cells and primary CD4(+) T lymphocytes probably by induction of macropinocytosis, although these cells are resistant to PTD-mediated protein delivery as a consequence of poor heparan sulfate expression. The anti-apoptotic protein Bcl-xL delivered by cCHP nanogels efficiently blocked apoptosis of these cells, establishing functional regulation of cells by proteins delivered by cCHP nanogels. Thus, cCHP nanogel is a useful tool to deliver proteins for development of new cancer therapy and immune regulation. PMID:21605901

  15. 含热电联供系统的微网经济运行%Economic operation of microgrid with combined heat and power system

    Institute of Scientific and Technical Information of China (English)

    吴雄; 王秀丽; 别朝红; 王建学

    2013-01-01

    为了分析热电联供系统和储能技术的经济节能作用,在分时电价以及微网并网运行的环境下,建立包含光伏、风电、热电联供系统、燃料电池以及储能系统的微网经济优化模型.采用方程线性化的方法将优化问题转化为混合整数线性规划(MILP)问题.算例分析验证了模型与算法的准确性,并比较了微网采用与不采用热电联供系统以及采用储能单元的经济效益,结果表明热电联供系统具有显著的经济效益,电储能带来的经济效益比热储能高.%For analyzing the economic and energy-saving effect of CHP(Combined Heat and Power) and energy storage,an economic optimal model including photovoltaic,wind power,CHP system,fuel cell and energy storage system is built for grid-connected microgrid with time-dependent electricity price.Equation linearization is used to convert the optimization problem into the MILP(Mixed-Integer Linear Programming) problem.Case analysis verifies the correctness of the proposed model and algorithm.The economic benefits are compared between the microgrids with and without the CHP system and energy storage unit,which shows that,CHP system has significant economic effect and the economic benefit brought by electric energy storage is higher than that by heat energy storage.

  16. Cis-hydroxyproline-induced inhibition of pancreatic cancer cell growth is mediated by endoplasmic reticulum stress

    Institute of Scientific and Technical Information of China (English)

    Christoph Mueller; Joerg Emmrich; Robert Jaster; Dagmar Braun; Stefan Liebe; Gisela Sparmann

    2006-01-01

    AIM: To investigate the biological effects of cishydroxyproline (CHP) on the rat pancreatic carcinoma cell line DSL6A, and to examine the underlying molecular mechanisms.METHODS: The effect of CHP on DSL6A cell proliferation was assessed by using BrdU incorporation. The expression of focal adhesion kinase (FAK) was characterized by Western blotting and immunofluorescence.Induction of endoplasmic reticulum (ER) stress was investigated by using RT-PCR and Western blotting for the glucose-related protein-78 (GRP78) and growth arrest and DNA inducible gene (GADD153). Cell viability was determined through measuring the metabolic activity based on the reduction potential of DSL6A cells. Apoptosis was analyzed by detection of caspase-3 activation and cleavage of poly(ADP-ribose) polymerase (PARP) as well as DNA laddering.RESULTS: In addition to inhibition of proliferation,incubation with CHP induced proteolytic cleavage of FAK and a delocalisation of the enzyme from focal adhesions,followed by a loss of cell adherence. Simultaneously,we could show an increased expression of GRP78 and GADD153, indicating a CHP-mediated activation of the ER stress cascade in the DSL6A cell line. Prolonged incubation of DSL6A cells with CHP finally resulted in apoptotic cell death. Beside L-proline, the inhibition of intracellular proteolysis by addition of a broad spectrum protease inhibitor could abolish the effects of CHP on cellular functions and the molecular processes. In contrast, impeding the activity of apoptosis-executing caspases had no influence on CHP-mediated cell damage.CONCLUSION: Our data suggest that the initiation of ER stress machinery by CHP leads to an activation of intracellular proteolytic processes, including caspaseindependent FAK degradation, resulting in damaging pancreatic carcinoma cells.

  17. Mammalian Cell-Based Sensor System

    Science.gov (United States)

    Banerjee, Pratik; Franz, Briana; Bhunia, Arun K.

    Use of living cells or cellular components in biosensors is receiving increased attention and opens a whole new area of functional diagnostics. The term "mammalian cell-based biosensor" is designated to biosensors utilizing mammalian cells as the biorecognition element. Cell-based assays, such as high-throughput screening (HTS) or cytotoxicity testing, have already emerged as dependable and promising approaches to measure the functionality or toxicity of a compound (in case of HTS); or to probe the presence of pathogenic or toxigenic entities in clinical, environmental, or food samples. External stimuli or changes in cellular microenvironment sometimes perturb the "normal" physiological activities of mammalian cells, thus allowing CBBs to screen, monitor, and measure the analyte-induced changes. The advantage of CBBs is that they can report the presence or absence of active components, such as live pathogens or active toxins. In some cases, mammalian cells or plasma membranes are used as electrical capacitors and cell-cell and cell-substrate contact is measured via conductivity or electrical impedance. In addition, cytopathogenicity or cytotoxicity induced by pathogens or toxins resulting in apoptosis or necrosis could be measured via optical devices using fluorescence or luminescence. This chapter focuses mainly on the type and applications of different mammalian cell-based sensor systems.

  18. IBCIS:Intelligent blood cell identification system

    Institute of Scientific and Technical Information of China (English)

    Adnan Khashman

    2008-01-01

    The analysis of blood cells in microscope images can provide useful information concerning the health of patients.There are three major blood cell types,namely,erythrocytes (red),leukocytes (white),and platelets.Manual classification is time consuming and susceptible to error due to the different morphological features of the cells.This paper presents an intelligent system that simulates a human visual inspection and classification of the three blood cell types.The proposed system comprises two phases:The image preprocessing phase where blood cell features are extracted via global pattern averaging,and the neural network arbitration phase where training is the first and then classification is carried out.Experimental results suggest that the proposed method performs well in identifying blood cell types regardless of their irregular shapes,sizes and orientation,thus providing a fast,simple and efficient rotational and scale invariant blood cell identification system which can be used in automating laboratory reporting.

  19. Economic Potential of CHP in Detroit Edison Service Area: the Customer Perspective

    Energy Technology Data Exchange (ETDEWEB)

    Kelly, J.

    2003-10-10

    can realistically be expected, based on consumer investment in combined heat and power systems (CHP) and the effect of utility applied demand response (DR). (2) Evaluate and quantify the impact on the distribution utility feeder from the perspective of customer ownership of the DE equipment. (3) Determine the distribution feeder limits and the impact DE may have on future growth. For the case study, the Gas Technology Institute analyzed a single 16-megawatt grid feeder circuit in Ann Arbor, Michigan to determine whether there are economic incentives to use small distributed power generation systems that would offset the need to increase grid circuit capacity. Increasing circuit capacity would enable the circuit to meet consumer's energy demands at all times, but it would not improve the circuit's utilization factor. The analysis spans 12 years, to a planning horizon of 2015. By 2015, the demand for power is expected to exceed the grid circuit capacity for a significant portion of the year. The analysis was to determine whether economically acceptable implementation of customer-owned DE systems would reduce the peak power demands enough to forestall the need to upgrade the capacity of the grid circuit. The analysis was based on economics and gave no financial credit for improved power reliability or mitigation of environmental impacts. Before this study was completed, the utility expanded the capacity of the circuit to 22 MW. Although this expansion will enable the circuit to meet foreseeable increases in peak demand, it also will significantly decrease the circuit's overall utilization factor. The study revealed that DE penetration on the selected feeder is not expected to forestall the need to upgrade the grid circuit capacity unless interconnection barriers are removed. Currently, a variety of technical, business practice, and regulatory barriers discourage DE interconnection in the US market.

  20. Combined Heat and Power (CHP) as a Compliance Option under the Clean Power Plan: A Template and Policy Options for State Regulators

    Energy Technology Data Exchange (ETDEWEB)

    None

    2015-07-30

    Combined Heat and Power (CHP) is an important option for states to consider in developing strategies to meet their emission targets under the US Environmental Protection Agency's Clean Power Plan. This Template is designed to highlight key issues that states should consider when evaluating whether CHP could be a meaningful component of their compliance plans. It demonstrates that CHP can be a valuable approach for reducing emissions and helping states achieve their targets. While the report does not endorse any particular approach for any state, and actual plans will vary dependent upon state-specific factors and determinations, it provides tools and resources that states can use to begin the process, and underscores the opportunity CHP represents for many states. . By producing both heat and electricity from a single fuel source, CHP offers significant energy savings and carbon emissions benefits over the separate generation of heat and power, with a typical unit producing electricity with half the emissions of conventional generation. These efficiency gains translate to economic savings and enhanced competitiveness for CHP hosts, and emissions reductions for the state, along with helping to lower electric bills; and creating jobs in the design, construction, installation and maintenance of equipment. In 2015, CHP represents 8 percent of electric capacity in the United States and provides 12 percent of total power generation. Projects already exist in all 50 states, but significant technical and economic potential remains. CHP offers a tested way for states to achieve their emission limits while advancing a host of ancillary benefits.

  1. Fuel cell using a hydrogen generation system

    Science.gov (United States)

    Dentinger, Paul M.; Crowell, Jeffrey A. W.

    2010-10-19

    A system is described for storing and generating hydrogen and, in particular, a system for storing and generating hydrogen for use in an H.sub.2/O.sub.2 fuel cell. The hydrogen storage system uses beta particles from a beta particle emitting material to degrade an organic polymer material to release substantially pure hydrogen. In a preferred embodiment of the invention, beta particles from .sup.63Ni are used to release hydrogen from linear polyethylene.

  2. Solid oxide fuel cells towards real life applications. Final report

    Energy Technology Data Exchange (ETDEWEB)

    2010-07-01

    Solid Oxide Fuel Cells offer a clean and efficient way of producing electricity and heat from a wide selection of fuels. The project addressed three major challenges to be overcome by the technology to make commercialisation possible. (1) At the cell level, increased efficiency combined with production cost reduction has been achieved through an optimization of the manufacturing processes, b) by using alternative raw materials with a lower purchase price and c) by introducing a new generation of fuel cells with reduced loss and higher efficiency. (2) At the stack level, production cost reduction is reduced and manufacturing capacity is increased through an optimization of the stack production. (3) At the system level, development of integrated hotbox concepts for the market segments distributed generation (DG), micro combined heat and power (mCHP), and auxiliary power units (APU) have been developed. In the mCHP segment, two concepts have been developed and validated with regards to market requirements and scalability. In the APU-segment, different types of reformers have been tested and it has been proven that diesel can be reformed through appropriate reformers. Finally, operation experience and feedback has been gained by deployment of stacks in the test facility at the H.C. OErsted Power Plant (HCV). This demonstration has been carried out in collaboration between TOFC and DONG Energy Power A/S (DONG), who has participated as a subcontractor to TOFC. The demonstration has given valuable knowledge and experience with design, start-up and operation of small power units connected to the grid and future development within especially the mCHP segment will benefit from this. In this report, the project results are described for each of the work packages in the project. (Author)

  3. SOSYAL POLİTİKA AÇISINDAN CHP İLE AKP’NİN KARŞILAŞTIRILMASI

    OpenAIRE

    YURDAKUL, Nilay BAŞOK; DİNÇER, Müjde Ker; BAT, Mikail

    2012-01-01

    Bu çalışmada siyasal yelpazedeki yerini sosyal demokrat olarak tanımlayan CHP ile muhafazakâr sağ olarak tanımlayan AKP’nin, tarihsel ve betimsel araştırma yöntemleri ışığında benimsediği ekonomi anlayışının ortaya konularak, izledikleri sosyal politikaların bu çerçevede irdelenmesi amaçlanmıştır. Bu bağlamda, CHP ile AKP’nin ekonomi politikası ortaya konduktan sonra, her iki partinin ekonomi politikaları benzerlik ve farklılık bakımından karşılaştırılmıştır. Daha sonra da CHP ile AKP’nin iz...

  4. CHP-II: The Carnegie Hubble Program to Measure Ho to 3% Using Population II

    Science.gov (United States)

    Rich, Jeffrey; Freedman, Wendy L.; Madore, Barry F.; Monson, Andy; Scowcroft, Victoria; Beaton, Rachael; Kollmeier, Juna A.; Seibert, Mark; Bono, Giuseppe; Clementini, Gisella; Yang, Soung-Chul; Lee, Myung Gyoon; Jang, In Sung

    2015-01-01

    There has been great progress in the measurement of cosmological parameters in recent years, but controversy has arisen over the Planck/WMAP versus the direct measurement of the Hubble constant. The goal of our Carnegie Hubble Program (CHP) is to obtain a direct measure of Ho to 3%. In CHP I, we used Cepheid variables to calibrate the extragalactic distance scale. In the second phase, CHP II, we are establishing a completely independent route to Ho using RR Lyrae variables, the tip of the red giant branch (TRGB) and Type Ia supernovae (SNe Ia). Not only is the RR Lyrae route independent of the Cepheids, but its PL relation has a scatter that is a factor of 2 smaller. Unlike the Cepheids, the RR Lyrae / TRGB distance scale can be applied to both elliptical and spiral galaxies. This is a great systematic advantage, given the small number of galaxies (9 in total) close enough to have measured Cepheid calibrators within the SNIa hosts. By providing a new calibration using a Pop II distance scale, we will immediately double the number of SN Ia distances based on geometry, linking to over 200 SNe in the pure Hubble flow out to z = 0.7. Four calibrators containing both Cepheids and TRGB stars provide an important cross-check on systematics. Initially, the accuracy of our value of Ho will be set by four galactic RR Lyrae calibrators with HST/FGS parallaxes. With Gaia, both the RR Lyrae zero point and TRGB method will be independently calibrated with at least an order of magnitude more calibrators, each having precisions of 1% or better. This will allow the highest accuracy measurement of Ho to date using the "Distance Ladder" method.

  5. Modelling the Italian household sector at the municipal scale: Micro-CHP, renewables and energy efficiency

    International Nuclear Information System (INIS)

    This study investigates the potential of energy efficiency, renewables, and micro-cogeneration to reduce household consumption in a medium Italian town and analyses the scope for municipal local policies. The study also investigates the effects of tourist flows on town's energy consumption by modelling energy scenarios for permanent and summer homes. Two long-term energy scenarios (to 2030) were modelled using the MarkAL-TIMES generator model: BAU (business as usual), which is the reference scenario, and EHS (exemplary household sector), which involves targets of penetration for renewables and micro-cogeneration. The analysis demonstrated the critical role of end-use energy efficiency in curbing residential consumption. Cogeneration and renewables (PV (photovoltaic) and solar thermal panels) were proven to be valuable solutions to reduce the energetic and environmental burden of the household sector (−20% in 2030). Because most of household energy demand is ascribable to space-heating or hot water production, this study finds that micro-CHP technologies with lower power-to-heat ratios (mainly, Stirling engines and microturbines) show a higher diffusion, as do solar thermal devices. The spread of micro-cogeneration implies a global reduction of primary energy but involves the internalisation of the primary energy, and consequently CO2 emissions, previously consumed in a centralised power plant within the municipality boundaries. - Highlights: • Energy consumption in permanent homes can be reduced by 20% in 2030. • High efficiency appliances have different effect according to their market penetration. • Use of electrical heat pumps shift consumption from natural gas to electricity. • Micro-CHP entails a global reduction of energy consumption but greater local emissions. • The main CHP technologies entering the residential market are Stirling and μ-turbines

  6. Anuário Investigação CHP 2008

    OpenAIRE

    DEFI

    2011-01-01

    Documenta-se a produção científica do Centro Hospitalar do Porto (CHP) apresentando os artigos da autoria ou co-autoria dos profissionais das três instituições nele integradas (Hospital de Santo António, HSA; Hospital Maria Pia, HMP; Maternidade Júlio Dinis, MJD) publicados em revistas científicas, durante o ano 2008.1 A listagem foi elaborada pelo Departamento de Ensino, Formação e Investigação (DEFI), com base em pesquisas em bases de dados bibliográficos. Consideram-se se...

  7. Economic feasibility of CHP facilities fueled by biomass from unused agriculture land

    DEFF Research Database (Denmark)

    Pfeifer, Antun; Dominkovic, Dominik Franjo; Ćosić, Boris;

    2016-01-01

    In this paper, the energy potential of biomass from growing short rotation coppice on unused agricultural land in the Republic of Croatia is used to investigate the feasibility of Combined Heat and Power (CHP) facilities fueled by such biomass. Large areas of agricultural land that remain unused...... work and is now used to investigate the conditions in which such energy facilities could be feasible. The overall potential of biomass from short rotation coppice cultivated on unused agricultural land in the scenarios with 30% of the area is up to 10PJ/year. The added value of fruit trees pruning...

  8. Intergovernmental Advanced Stationary PEM Fuel Cell System Demonstration Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Rich Chartrand

    2011-08-31

    A program to complete the design, construction and demonstration of a PEMFC system fuelled by Ethanol, LPG or NG for telecom applications was initiated in October 2007. Early in the program the economics for Ethanol were shown to be unfeasible and permission was given by DOE to focus on LPG only. The design and construction of a prototype unit was completed in Jun 2009 using commercially available PEM FC stack from Ballard Power Systems. During the course of testing, the high pressure drop of the stack was shown to be problematic in terms of control and stability of the reformer. Also, due to the power requirements for air compression the overall efficiency of the system was shown to be lower than a similar system using internally developed low pressure drop FC stack. In Q3 2009, the decision was made to change to the Plug power stack and a second prototype was built and tested. Overall net efficiency was shown to be 31.5% at 3 kW output. Total output of the system is 6 kW. Using the new stack hardware, material cost reduction of 63% was achieved over the previous Alpha design. During a November 2009 review meeting Plug Power proposed and was granted permission, to demonstrate the new, commercial version of Plug Power's telecom system at CERL. As this product was also being tested as part of a DOE Topic 7A program, this part of the program was transferred to the Topic 7A program. In Q32008, the scope of work of this program was expanded to include a National Grid demonstration project of a micro-CHP system using hightemperature PEM technology. The Gensys Blue system was cleared for unattended operation, grid connection, and power generation in Aug 2009 at Union College in NY state. The system continues to operate providing power and heat to Beuth House. The system is being continually evaluated and improvements to hardware and controls will be implemented as more is learned about the system's operation. The program is instrumental in improving the

  9. Failure analysis of electrolyte-supported solid oxide fuel cells

    Science.gov (United States)

    Fleischhauer, Felix; Tiefenauer, Andreas; Graule, Thomas; Danzer, Robert; Mai, Andreas; Kuebler, Jakob

    2014-07-01

    For solid oxide fuel cells (SOFCs) one key aspect is the structural integrity of the cell and hence its thermo mechanical long term behaviour. The present study investigates the failure mechanisms and the actual causes for fracture of electrolyte supported SOFCs which were run using the current μ-CHP system of Hexis AG, Winterthur - Switzerland under lab conditions or at customer sites for up to 40,000 h. In a first step several operated stacks were demounted for post-mortem inspection, followed by a fractographic evaluation of the failed cells. The respective findings are then set into a larger picture including an analysis of the present stresses acting on the cell like thermal and residual stresses and the measurements regarding the temperature dependent electrolyte strength. For all investigated stacks, the mechanical failure of individual cells can be attributed to locally acting bending loads, which rise due to an inhomogeneous and uneven contact between the metallic interconnect and the cell.

  10. Solid oxide fuel cell power system development

    Energy Technology Data Exchange (ETDEWEB)

    Kerr, Rick [Delphi Automotive Systems, LLC., Troy, MI (United States); Wall, Mark [Independent Energy Partners Technology, LLC., Parker, CO (United States); Sullivan, Neal [Colorado School of Mines, Golden, CO (United States)

    2015-06-26

    This report summarizes the progress made during this contractual period in achieving the goal of developing the solid oxide fuel cell (SOFC) cell and stack technology to be suitable for use in highly-efficient, economically-competitive, commercially deployed electrical power systems. Progress was made in further understanding cell and stack degradation mechanisms in order to increase stack reliability toward achieving a 4+ year lifetime, in cost reduction developments to meet the SECA stack cost target of $175/kW (in 2007 dollars), and in operating the SOFC technology in a multi-stack system in a real-world environment to understand the requirements for reliably designing and operating a large, stationary power system.

  11. Techno-Economic Study of Adsorption Processes for Pre-Combustion Carbon Capture at a Biomass CHP Plant

    OpenAIRE

    Oreggioni, Gabriel David; Friedrich, Daniel; Brandani, Stefano; Ahn, Hyungwoong

    2014-01-01

    An exemplary 10 MWth biomass CHP plant with a FICFB (Fast Internally Circulating Fluidised Bed) gasifier and Jenbacher type 6 gas engine was simulated to estimate the power and thermal outputs. The biomass-fuelled CHP plant was modified for carbon capture using either adsorption or amine process. It was found that a two-stage, two-bed PVSA (Pressure Vacuum Swing Adsorption) unit applied to syngas stream for pre-combustion capture spent less specific energy per captured CO2 than a conventional...

  12. Increasing the flexibility of operational scheduling for a large-scale CHP plant used for generating district heat and electricity in order to meet the varying market demands

    International Nuclear Information System (INIS)

    The substantial changes in the structure of German power supply plants pose high demands on the flexibility of the operational scheduling of conventional thermal power plants. Grosskraftwerk Mannheim AG is a power plant company that is operating a plant for combined power and district heat generation. The paper describes some measures which have been taken to improve the plant's operational flexibility. In addition, the associated technical systems and their functions, as well as the state of ongoing projects are outlined. Special focus is placed on topics related to issues such as ''district-heat storage unit of the new unit 9, flexibility of operational scheduling, and efficient CHP plant operation''.

  13. Monitoring of the energy performance of a district heating CHP plant based on biomass boiler and ORC generator

    International Nuclear Information System (INIS)

    More than seventy district heating (DH) plants based on biomass are operating in South Tyrol (Italy) and most of them supply heat to residential districts. Almost 20% of them are cogenerative systems, thus enabling primary energy savings with respect to the separate production of heat and power. However, the actual performance of these systems in real operation can considerably differ from the nominal one. The main objectives of this work are the assessment of the energy performance of a biomass boiler coupled with an Organic Rankine Cycle (i.e. ORC) generator under real operating conditions and the identification of its potential improvements. The fluxes of energy and mass of the plant have been measured onsite. This experimental evaluation has been supplemented with a thermodynamic model of the ORC generator, calibrated with the experimental data, which is capable to predict the system performance under different management strategies of the system. The results have highlighted that a decrease of the DH network temperature of 10 °C can improve the electric efficiency of the ORC generator of one percentage point. Moreover, a DH temperature reduction could decrease the main losses of the boiler, namely the exhaust latent thermal loss and the exhaust sensible thermal loss, which account for 9% and 16% of the boiler input power, respectively. The analysis of the plant has pointed out that the ORC pump, the flue gases extractor, the thermal oil pump and the condensation section fan are the main responsible of the electric self-consumption. Finally, the negative effect of the subsidisation on the performance of the plant has been discussed. - Highlights: • Energy performance of a biomass boiler coupled to an ORC turbine in real operation. • Potential improvements of a CHP plant connected to a DH network. • Performance prediction by means of a calibrated ORC thermodynamic model. • Influence of the DH temperature on the electric efficiency. • Impact of the

  14. Automated microinjection system for adherent cells

    Science.gov (United States)

    Youoku, Sachihiro; Suto, Yoshinori; Ando, Moritoshi; Ito, Akio

    2007-07-01

    We have developed an automated microinjection system that can handle more than 500 cells an hour. Microinjection injects foreign agents directly into cells using a micro-capillary. It can randomly introduce agents such as DNA, proteins and drugs into various types of cells. However, conventional methods require a skilled operator and suffer from low throughput. The new automated microinjection techniques we have developed consist of a Petri dish height measuring method and a capillary apex position measuring method. The dish surface height is measured by analyzing the images of cells that adhere to the dish surface. The contrast between the cell images is minimized when the focus plane of an object lens coincides with the dish surface. We have developed an optimized focus searching method with a height accuracy of +/-0.2 um. The capillary apex position detection method consists of three steps: rough, middle, and precise. These steps are employed sequentially to cover capillary displacements of up to +/-2 mm, and to ultimately accomplish an alignment accuracy of less than one micron. Experimental results using this system we developed show that it can introduce fluorescent material (Alexa488) into adherent cells, HEK293, with a success rate of 88.5%.

  15. Cell-based bioassays in microfluidic systems

    Science.gov (United States)

    Itle, Laura J.; Zguris, Jeanna C.; Pishko, Michael V.

    2004-12-01

    The development of cell-based bioassays for high throughput drug screening or the sensing of biotoxins is contingent on the development of whole cell sensors for specific changes in intracellular conditions and the integration of those systems into sample delivery devices. Here we show the feasibility of using a 5-(and-6)-carboxy SNARF-1, acetoxymethyl ester, acetate, a fluorescent dye capable of responding to changes in intracellular pH, as a detection method for the bacterial endotoxin, lipopolysaccharide. We used photolithography to entrap cells with this dye within poly(ethylene) glyocol diacrylate hydrogels in microfluidic channels. After 18 hours of exposure to lipopolysaccharide, we were able to see visible changes in the fluorescent pattern. This work shows the feasibility of using whole cell based biosensors within microfluidic networks to detect cellular changes in response to exogenous agents.

  16. Fuel cell technology for prototype logistic fuel cell mobile systems

    Energy Technology Data Exchange (ETDEWEB)

    Sederquist, R.A.; Garow, J.

    1995-08-01

    Under the aegis of the Advanced Research Project Agency`s family of programs to develop advanced technology for dual use applications, International Fuel Cells Corporation (IFC) is conducting a 39 month program to develop an innovative system concept for DoD Mobile Electric Power (MEP) applications. The concept is to integrate two technologies, the phosphoric acid fuel cell (PAFC) with an auto-thermal reformer (ATR), into an efficient fuel cell power plant of nominally 100-kilowatt rating which operates on logistic fuels (JP-8). The ATR fuel processor is the key to meeting requirements for MEP (including weight, volume, reliability, maintainability, efficiency, and especially operation on logistic fuels); most of the effort is devoted to ATR development. An integrated demonstration test unit culminates the program and displays the benefits of the fuel cell system, relative to the standard 100-kilowatt MEP diesel engine generator set. A successful test provides the basis for proceeding toward deployment. This paper describes the results of the first twelve months of activity during which specific program aims have remained firm.

  17. Survey of controllability in decentralized CHP plants. Optimal operation of priority production units; Kortlaegning af decentrale kraftvarmevaerkers regulerbarhed. Optimal drift af prioriterede anlaeg - Teknologisk grundlag

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-03-15

    'Danske Fjernvarmevaerkers Forening' (DFF) and 'Energistyrelsens energiproducenttaelling' (EEPT) are used. In the part project 'Teknologisk grundlag', project 4712, the technical information on decentralized CHP plants has been arranged in such a way that it is suitable for being used in a bid model, developed in project 4712, for selling electricity production on the Nordic spot market, NORDPOOL. A number of typical technical and operational parameters have been mapped and their distributions in subgroups of plant types. It concerns primarily, capacity on electricity and heat production, the connected heat storage capacity, the demand of heat in the connected district heating system, efficiencies at full and part load, start and stop times and maximum load gradients. Options and restrictions regarding the SCR system concerning the possibility of remote operation, likelihood of error, manning, wear, costs associated with start/stop and cost of operation and maintenance are investigated. Investment costs are estimated on possible modifications of plant equipment either for more flexible production and thereby improved economics or for improved controllability. It includes cost estimation of additional equipment for removing surplus of heat in order to eliminate the locked-up electricity production to the heat demand in the district heating system. Thereby making it possible to generate electricity when electricity price is very high no matter the demand of heat. Opposite, in case electricity price is very low, the possibility of using electricity for heat generation (electric cartridge or heat pump) is considered. Finally, the environmental impact of a new operational strategy of the CHP plants possibly with more start/stop and part load operation is discussed.

  18. Technical preparation of a 300 kWel biomass gasification plant. Report for the project: Simplification, system and operation optimization of staged gasification unit for CHP production (the Castor unit in Graested); Teknisk forberedelse af 300 kWel bioforgasningsanlaeg. En Delrapport til projektet: Forenkling, system- og driftsoptimering af trinopdelt forgasningsanlaeg til kraftvarmeproduktion (Castor anlaegget i Graested)

    Energy Technology Data Exchange (ETDEWEB)

    Houmann Jakobsen, H.

    2009-09-15

    In 2003/04 BioSynergi Proces ApS built a complete approx. 450 kWth Open Core staged gasification unit as a development / demonstration plant. The plant uses wet wood chips as fuel for generating electricity and heat. The facility, known as the Castor plant, is connected to the heat supply network in Graested District Heating. The daily operation is handled by BioSynergi Process. The cogeneration system, that the Castor plant represents, is the basis for this completed project. For technical preparation of the planned future up scaling of the cogeneration system, a test of the function of the gas generator core (reactor core) was performed in this sub-project. It is the central component of the total cogeneration system, and it is also the one who has the greatest influence on the overall gasification process. The experiments have demonstrated that the stage gasification principle, which is in operation at the Castor plant, is also possible to have in operation with the desired process steps in the tested reactor core with four times more capacity. Finalization of the total gas generator in the range of 300 kWel is now being developed in a new project. The simplified experiments, that were possible to perform with the outdoor setup of the reactor core, were, however, not suited to qualitative assessments of the gasification process. (ln)

  19. Coal Integrated Gasification Fuel Cell System Study

    Energy Technology Data Exchange (ETDEWEB)

    Chellappa Balan; Debashis Dey; Sukru-Alper Eker; Max Peter; Pavel Sokolov; Greg Wotzak

    2004-01-31

    This study analyzes the performance and economics of power generation systems based on Solid Oxide Fuel Cell (SOFC) technology and fueled by gasified coal. System concepts that integrate a coal gasifier with a SOFC, a gas turbine, and a steam turbine were developed and analyzed for plant sizes in excess of 200 MW. Two alternative integration configurations were selected with projected system efficiency of over 53% on a HHV basis, or about 10 percentage points higher than that of the state-of-the-art Integrated Gasification Combined Cycle (IGCC) systems. The initial cost of both selected configurations was found to be comparable with the IGCC system costs at approximately $1700/kW. An absorption-based CO2 isolation scheme was developed, and its penalty on the system performance and cost was estimated to be less approximately 2.7% and $370/kW. Technology gaps and required engineering development efforts were identified and evaluated.

  20. Combined heat and power generation with fuel cells in residential buildings in the future energy system; Kraft-Waerme-Kopplung mit Brennstoffzellen in Wohngebaeuden im zukuenftigen Energiesystem

    Energy Technology Data Exchange (ETDEWEB)

    Jungbluth, C.H.

    2007-04-27

    Combined heat and power generation (CHP) is regarded as one of the cornerstones of a future sustainable energy system. The application of this approach can be substantially extended by employing fuel cell technologies in small units for supplying heat to residential buildings. This could create an additional market for combined heat and power generation corresponding to approx. 25% of the final energy demand in Germany today. In parallel, the extensive application of distributed fuel cell systems in residential buildings would have substantial effects on energy infrastructures, primary energy demand, the energy mix and greenhouse gas emissions. It is the aim of the present study to quantify these effects via scenario modelling of energy demand and supply for Germany up to the year 2050. Two scenarios, reference and ecological commitment, are set up, and the application and operation of fuel cell plants in the future stock of residential buildings is simulated by a bottom-up approach. A model of the building stock was developed for this purpose, consisting of 213 types of reference buildings, as well as detailed simulation models of the plant operation modes. The aim was, furthermore, to identify economically and ecologically optimised plant designs and operation modes for fuel cells in residential buildings. Under the assumed conditions of the energy economy, economically optimised plant sizes for typical one- or two-family homes are in the range of a generating capacity of a few hundred watts of electrical power. Plant sizes of 2 to 4.7 kW{sub el} as discussed today are only economically feasible in multifamily dwellings. The abolition of the CHP bonus reduces profitability, especially for larger plants operated by contractors. In future, special strategies for power generation and supply can be an economically useful addition for the heat-oriented operation mode of fuel cells. On the basis of the assumed conditions of the energy economy, a technical potential for

  1. The large-scale digital cell analysis system: an open system for nonperturbing live cell imaging.

    Science.gov (United States)

    Davis, Paul J; Kosmacek, Elizabeth A; Sun, Yuansheng; Ianzini, Fiorenza; Mackey, Michael A

    2007-12-01

    The Large-Scale Digital Cell Analysis System (LSDCAS) was designed to provide a highly extensible open source live cell imaging system. Analysis of cell growth data has demonstrated a lack of perturbation in cells imaged using LSDCAS, through reference to cell growth data from cells growing in CO(2) incubators. LSDCAS consists of data acquisition, data management and data analysis software, and is currently a Core research facility at the Holden Comprehensive Cancer Center at the University of Iowa. Using LSDCAS analysis software, this report and others show that although phase-contrast imaging has no apparent effect on cell growth kinetics and viability, fluorescent image acquisition in the cell lines tested caused a measurable level of growth perturbation using LSDCAS. This report describes the current design of the system, reasons for the implemented design, and details its basic functionality. The LSDCAS software runs on the GNU/Linux operating system, and provides easy to use, graphical programs for data acquisition and quantitative analysis of cells imaged with phase-contrast or fluorescence microscopy (alone or in combination), and complete source code is freely available under the terms of the GNU Public Software License at the project website (http://lsdcas.engineering.uiowa.edu). PMID:18045324

  2. Combined heat and power generation with a HCPV system at 2000 suns

    Energy Technology Data Exchange (ETDEWEB)

    Paredes, Filippo; Montagnino, Fabio M.; Milone, Sergio [IDEA s.r.l., C.da Molara Z.I. III Fase, 90018 Termini Imerese (Italy); Salinari, Piero; Agnello, Simonpietro; Gelardi, Franco M.; Sciortino, Luisa; Cannas, Marco [Dipartimento di Fisica e Chimica, Università di Palermo, Via Archirafi 36, 90123 Palermo (Italy); Bonsignore, Gaetano; Barbera, Marco [Dipartimento di Fisica e Chimica, Università di Palermo, Via Archirafi 36, 90123 Palermo (Italy); INAF, Osservatorio Astronomico di Palermo, Piazza del Parlamento 1, 90134 Palermo (Italy); Collura, Alfonso; Lo Cicero, Ugo [INAF, Osservatorio Astronomico di Palermo, Piazza del Parlamento 1, 90134 Palermo (Italy)

    2015-09-28

    This work shows the development of an innovative solar CHP system for the combined production of heat and power based upon HCPV modules working at the high concentration level of 2000 suns. The solar radiation is concentrated on commercial InGaP/InGaAs/Ge triple-junction solar cells designed for intensive work. The primary optics is a rectangular off-axis parabolic mirror while a secondary optic at the focus of the parabolic mirror is glued in optical contact with the cell. Each module consist of 2 axis tracker (Alt-Alt type) with 20 multijunction cells each one integrated with an active heat sink. The cell is connected to an active heat transfer system that allows to keep the cell at a high level of electrical efficiency (ηel > 30 %), bringing the heat transfer fluid (water and glycol) up to an output temperature of 90°C. Accordingly with the experimental data collected from the first 1 kWe prototype, the total amount of extracted thermal energy is above the 50% of the harvested solar radiation. That, in addition the electrical efficiency of the system contributes to reach an overall CHP efficiency of more than the 80%.

  3. Combined heat and power generation with a HCPV system at 2000 suns

    International Nuclear Information System (INIS)

    This work shows the development of an innovative solar CHP system for the combined production of heat and power based upon HCPV modules working at the high concentration level of 2000 suns. The solar radiation is concentrated on commercial InGaP/InGaAs/Ge triple-junction solar cells designed for intensive work. The primary optics is a rectangular off-axis parabolic mirror while a secondary optic at the focus of the parabolic mirror is glued in optical contact with the cell. Each module consist of 2 axis tracker (Alt-Alt type) with 20 multijunction cells each one integrated with an active heat sink. The cell is connected to an active heat transfer system that allows to keep the cell at a high level of electrical efficiency (ηel > 30 %), bringing the heat transfer fluid (water and glycol) up to an output temperature of 90°C. Accordingly with the experimental data collected from the first 1 kWe prototype, the total amount of extracted thermal energy is above the 50% of the harvested solar radiation. That, in addition the electrical efficiency of the system contributes to reach an overall CHP efficiency of more than the 80%

  4. Combined heat and power generation with a HCPV system at 2000 suns

    Science.gov (United States)

    Paredes, Filippo; Montagnino, Fabio M.; Salinari, Piero; Bonsignore, Gaetano; Milone, Sergio; Agnello, Simonpietro; Barbera, Marco; Gelardi, Franco M.; Sciortino, Luisa; Collura, Alfonso; Lo Cicero, Ugo; Cannas, Marco

    2015-09-01

    This work shows the development of an innovative solar CHP system for the combined production of heat and power based upon HCPV modules working at the high concentration level of 2000 suns. The solar radiation is concentrated on commercial InGaP/InGaAs/Ge triple-junction solar cells designed for intensive work. The primary optics is a rectangular off-axis parabolic mirror while a secondary optic at the focus of the parabolic mirror is glued in optical contact with the cell. Each module consist of 2 axis tracker (Alt-Alt type) with 20 multijunction cells each one integrated with an active heat sink. The cell is connected to an active heat transfer system that allows to keep the cell at a high level of electrical efficiency (ηel > 30 %), bringing the heat transfer fluid (water and glycol) up to an output temperature of 90°C. Accordingly with the experimental data collected from the first 1 kWe prototype, the total amount of extracted thermal energy is above the 50% of the harvested solar radiation. That, in addition the electrical efficiency of the system contributes to reach an overall CHP efficiency of more than the 80%.

  5. The financial viability of an SOFC cogeneration system in single-family dwellings

    Science.gov (United States)

    Alanne, Kari; Saari, Arto; Ugursal, V. Ismet; Good, Joel

    In the near future, fuel cell-based residential micro-CHP systems will compete with traditional methods of energy supply. A micro-CHP system may be considered viable if its incremental capital cost compared to its competitors equals to cumulated savings during a given period of time. A simplified model is developed in this study to estimate the operation of a residential solid oxide fuel cell (SOFC) system. A comparative assessment of the SOFC system vis-à-vis heating systems based on gas, oil and electricity is conducted using the simplified model for a single-family house located in Ottawa and Vancouver. The energy consumption of the house is estimated using the HOT2000 building simulation program. A financial analysis is carried out to evaluate the sensitivity of the maximum allowable capital cost with respect to system sizing, acceptable payback period, energy price and the electricity buyback strategy of an energy utility. Based on the financial analysis, small (1-2 kW e) SOFC systems seem to be feasible in the considered case. The present study shows also that an SOFC system is especially an alternative to heating systems based on oil and electrical furnaces.

  6. A comparison of cost-benefit analysis of biomass and natural gas CHP projects in Denmark and the Netherlands

    NARCIS (Netherlands)

    Groth, Tanja; Scholtens, Bert

    2016-01-01

    We investigate what drives differences in the project appraisal of biomass and natural gas combined heat and power (CHP) projects in two countries with very similar energy profiles. This is of importance as the European Commission is assessing the potential scope of harmonizing renewable electricity

  7. In-situ corrosion investigation at Masnedø CHP plant - a straw-fired power plant

    DEFF Research Database (Denmark)

    Montgomery, Melanie; Karlsson, Asger

    1999-01-01

    Various austenitic and ferritic steels were exposed on a water-cooled probe in the superheater area of a straw-fired CHP plant. The temperature of the probe ranged from 450-600°C and the period of exposure was 1400 hours. The rate of corrosion was assessed based on unattacked metal remaining. The...

  8. 75 FR 13090 - Privacy Act of 1974; System of Records

    Science.gov (United States)

    2010-03-18

    ...,'' dated February 8, 1996 (February 20, 1996; 61 FR 6427). ] Dated: March 15, 2010. Mitchell S. Bryman... of the system: 5 U.S.C. 301, Departmental Regulation; 10 U.S.C. Chp. 8, Defense Agencies...

  9. Transient Stability Improvement for Combined Heat and Power System Using Load Shedding

    OpenAIRE

    2014-01-01

    The purpose of the paper is to analyze and improve the transient stability of an industrial combined heat and power (CHP) system in a high-tech science park in Taiwan. The CHP system installed two 161 kV/161 kV high-impendence transformers to connect with Taipower System (TPS) for both decreasing the short-circuit fault current and increasing the fault critical clearing time. The transient stabilities of three types of operation modes in CHP units, 3G1S, 2G1S, and 1G1S, are analyzed. Under th...

  10. Energetic-environmental-economic assessment of the biogas system with three utilization pathways: Combined heat and power, biomethane and fuel cell.

    Science.gov (United States)

    Wu, Bin; Zhang, Xiangping; Shang, Dawei; Bao, Di; Zhang, Suojiang; Zheng, Tao

    2016-08-01

    A typical biogas system with three utilization pathways, i.e., biogas upgrading, biogas combined heat and power (CHP), biogas solid oxide fuel cells (SOFCs) were designed. It was assessed from the viewpoint of energy, environment and economy by using energy efficiency, green degree and net present value index respectively. The assessment considered the trade-off relationships among these indexes, which is more comprehensive than previous systematic evaluation work only included single or two of the pathway(s) by using one or two of the index(es). Assessment results indicated that biogas upgrading pathway has the highest systematic energy efficiency (46.5%) and shortest payback period (8.9year) with the green degree production is the lowest (9.29gd/day). While for biogas SOFC pathway, although the green degree production is the highest (21.77gd/day), the payback period is longer (14.5year) and the energy efficiency is 13.6% lower than the biogas upgrading pathway. PMID:27209454

  11. Economic analysis of a supercritical coal-fired CHP plant integrated with an absorption carbon capture installation

    International Nuclear Information System (INIS)

    Energy investments in Poland are currently focused on supercritical coal-fired unit technology. It is likely, that in the future, these units are to be integrated with carbon capture and storage (CCS) installations, which enable a significant reduction of greenhouse gas emissions into the atmosphere. A significant share of the energy market in Poland is constituted by coal-fired combined heat and power (CHP) plants. The integration of these units with CCS installation can be economically inefficient. However, the lack of such integration enhances the investment risk due to the possibility of appearing on the market in the near future high prices of emission allowances. The aforementioned factors and additional favorable conditions for the development of cogeneration can cause one to consider investing in large supercritical CHP plants. This paper presents the results of an economic analysis aimed at comparing three cases of CHP plants, one without an integrated CCS installation and two with such installations. The same steam cycle structure for all variants was adopted. The cases of integrated CHP plants differ from each other in the manner in which they recover heat. For the evaluation of the respective solutions, the break-even price of electricity and avoided emission cost were used. - Highlights: • The simulations of operation of CHP plants under changing load have been realized. • For analyzed cases sensitivity analyses of economic indices have been conducted. • Conditions of competitiveness for integration with CCS units have been identified. • Integration can be profitable if prices of allowance will reach high values, exceeding 50 €/MgCO2. • Others important factors are the investment costs and operation and maintenance costs

  12. Comparison and Research of Standards for CHP Energy Efifciency%我国热电联产能效标准对比研究

    Institute of Scientific and Technical Information of China (English)

    齐为; 马娜

    2013-01-01

    Based on China’s standards on Combined Heating&Power (CHP) energy efifciency, this paper compares and researches the local energy efifciency standards on CHP, analyzes the local policies and industrial characters of CHP, as well as summarizes the conclusions of the comparison.%在梳理我国热电联产能效标准现状的基础上,对比研究我国地方热电联产能效标准,分析地方热电联产制度环境和产业特点,总结相应对比结论。

  13. Solid Oxide Fuel Cell Systems PVL Line

    Energy Technology Data Exchange (ETDEWEB)

    Susan Shearer - Stark State College; Gregory Rush - Rolls-Royce Fuel Cell Systems

    2012-05-01

    In July 2010, Stark State College (SSC), received Grant DE-EE0003229 from the U.S. Department of Energy (DOE), Golden Field Office, for the development of the electrical and control systems, and mechanical commissioning of a unique 20kW scale high-pressure, high temperature, natural gas fueled Stack Block Test System (SBTS). SSC worked closely with subcontractor, Rolls-Royce Fuel Cell Systems (US) Inc. (RRFCS) over a 13 month period to successfully complete the project activities. This system will be utilized by RRFCS for pre-commercial technology development and training of SSC student interns. In the longer term, when RRFCS is producing commercial products, SSC will utilize the equipment for workforce training. In addition to DOE Hydrogen, Fuel Cells, and Infrastructure Technologies program funding, RRFCS internal funds, funds from the state of Ohio, and funding from the DOE Solid State Energy Conversion Alliance (SECA) program have been utilized to design, develop and commission this equipment. Construction of the SBTS (mechanical components) was performed under a Grant from the State of Ohio through Ohio's Third Frontier program (Grant TECH 08-053). This Ohio program supported development of a system that uses natural gas as a fuel. Funding was provided under the Department of Energy (DOE) Solid-state Energy Conversion Alliance (SECA) program for modifications required to test on coal synthesis gas. The subject DOE program provided funding for the electrical build, control system development and mechanical commissioning. Performance testing, which includes electrical commissioning, was subsequently performed under the DOE SECA program. Rolls-Royce Fuel Cell Systems is developing a megawatt-scale solid oxide fuel cell (SOFC) stationary power generation system. This system, based on RRFCS proprietary technology, is fueled with natural gas, and operates at elevated pressure. A critical success factor for development of the full scale system is the capability

  14. Phase Space Cell in Nonextensive Classical Systems

    CERN Document Server

    Quarati, F

    2003-01-01

    We calculate the phase space volume $Omega$ occupied by a nonextensive system of $N$ classical particles described by an equilibrium (or steady-state, or long-term stationary state of a nonequilibrium system) distribution function, which slightly deviates from Maxwell-Boltzmann (MB) distribution in the high energy tail. We explicitly require that the number of accessible microstates does not change respect to the extensive MB case. We also derive, within a classical scheme, an analytical expression of the elementary cell that can be seen as a macrocell, different from the third power of Planck constant. Thermodynamic quantities like entropy, chemical potential and free energy of a classical ideal gas, depending on elementary cell, are evaluated. Considering the fractional deviation from MB distribution we can deduce a physical meaning of the nonextensive parameter $q$ of the Tsallis nonextensive thermostatistics in terms of particle correlation functions (valid at least in the case, discussed in this work, of...

  15. Systemic adjuvant therapies in renal cell carcinoma

    OpenAIRE

    Sebastiano Buti; Melissa Bersanelli; Maddalena Donini; Andrea Ardizzoni

    2012-01-01

    Renal cell carcinoma (RCC) is one of the ten most frequent solid tumors worldwide. Recent innovations in the treatment of metastatic disease have led to new therapeutic approaches being investigated in the adjuvant setting. Observation is the only current standard of care after radical nephrectomy, although there is evidence of efficacy of adjuvant use of vaccine among all the strategies used. This article aims to collect published experiences with systemic adjuvant approaches in RCC and to d...

  16. Regulated cell-to-cell variation in a cell-fate decision system.

    Science.gov (United States)

    Colman-Lerner, Alejandro; Gordon, Andrew; Serra, Eduard; Chin, Tina; Resnekov, Orna; Endy, Drew; Pesce, C Gustavo; Brent, Roger

    2005-09-29

    Here we studied the quantitative behaviour and cell-to-cell variability of a prototypical eukaryotic cell-fate decision system, the mating pheromone response pathway in yeast. We dissected and measured sources of variation in system output, analysing thousands of individual, genetically identical cells. Only a small proportion of total cell-to-cell variation is caused by random fluctuations in gene transcription and translation during the response ('expression noise'). Instead, variation is dominated by differences in the capacity of individual cells to transmit signals through the pathway ('pathway capacity') and to express proteins from genes ('expression capacity'). Cells with high expression capacity express proteins at a higher rate and increase in volume more rapidly. Our results identify two mechanisms that regulate cell-to-cell variation in pathway capacity. First, the MAP kinase Fus3 suppresses variation at high pheromone levels, while the MAP kinase Kss1 enhances variation at low pheromone levels. Second, pathway capacity and expression capacity are negatively correlated, suggesting a compensatory mechanism that allows cells to respond more precisely to pheromone in the presence of a large variation in expression capacity. PMID:16170311

  17. Combined cold heat and power generation. Techno-economic assessment of integrated fuel cell and sorption heat pump systems

    Energy Technology Data Exchange (ETDEWEB)

    Weeda, M.; Ruijg, G.J.; Van der Laag, P.C. [ECN Clean Fossil Fuels, Petten (Netherlands); Haije, W.G.; Smeding, S.F. [ECN Energie Efficiency in de Industrie, Petten (Netherlands); Kramer, G.J. [Shell Global Solutions, Den Haag (Netherlands)

    2002-11-01

    This report contains the results of a feasibility study into the possibility of combining a fuel processor/fuel cell (FP/FC) system with an adsorption-cooling device to convert the waste heat of the former into cold. Such a combination is in general referred to as trigeneration, denoting the simultaneous production of power, heat and cold. As starting point for this study a trigeneration system was proposed consisting of a PEMFC based CHP unit, equipped with a CPO based fuel processor of Shell (Hydrogen Source), and combined with the SWEAT solid sorption heat pump which is being developed at ECN. In addition, various alternative technologies have been considered as part of a trigeneration unit, both at the heat and power production side (SOFC, gas engine, gas turbine) as well as at the cold production side (silica/H2O and LiBr2-H2O sorption chillers). The trigeneration systems have been evaluated for surplus value in terms of energy saving compared to a reference situation consisting of cogeneration and production of cooling with an electric compression heat pump. The evaluation holds for a grid-connected situation, and own exploitation/ private ownership of facilities. It appears that in this situation, there is only potential for energy saving if the ratio of cooling efficiency of the trigeneration unit and the COP value of the reference cooling technology is larger than the difference between the average electrical efficiency of central power production and the electrical efficiency of the trigeneration unit. Most systems considered do not fulfil this criterion. Only trigeneration systems based on a Solid Oxide Fuel Cell with steam pre-reforming of fuel show potential. This appears to be not so much the result of a high cooling efficiency, but rather the result of a relatively high electrical efficiency. The application of trigeneration is illustrated by two case studies, the result of which indicate that combining cogeneration with a sorption cooler besides, or

  18. System for adding sulfur to a fuel cell stack system for improved fuel cell stability

    Science.gov (United States)

    Mukerjee, Subhasish; Haltiner, Jr., Karl J; Weissman, Jeffrey G

    2013-08-13

    A system for adding sulfur to a reformate stream feeding a fuel cell stack, having a sulfur source for providing sulfur to the reformate stream and a metering device in fluid connection with the sulfur source and the reformate stream. The metering device injects sulfur from the sulfur source to the reformate stream at a predetermined rate, thereby providing a conditioned reformate stream to the fuel cell stack. The system provides a conditioned reformate stream having a predetermined sulfur concentration that gives an acceptable balance of minimal drop in initial power with the desired maximum stability of operation over prolonged periods for the fuel cell stack.

  19. Single-cell twitching chemotaxis in developing biofilms.

    Science.gov (United States)

    Oliveira, Nuno M; Foster, Kevin R; Durham, William M

    2016-06-01

    Bacteria form surface-attached communities, known as biofilms, which are central to bacterial biology and how they affect us. Although surface-attached bacteria often experience strong chemical gradients, it remains unclear whether single cells can effectively perform chemotaxis on surfaces. Here we use microfluidic chemical gradients and massively parallel automated tracking to study the behavior of the pathogen Pseudomonas aeruginosa during early biofilm development. We show that individual cells can efficiently move toward chemoattractants using pili-based "twitching" motility and the Chp chemosensory system. Moreover, we discovered the behavioral mechanism underlying this surface chemotaxis: Cells reverse direction more frequently when moving away from chemoattractant sources. These corrective maneuvers are triggered rapidly, typically before a wayward cell has ventured a fraction of a micron. Our work shows that single bacteria can direct their motion with submicron precision and reveals the hidden potential for chemotaxis within bacterial biofilms. PMID:27222583

  20. COMPARISON OF MATHEMATICAL MODELS FOR HEAT EXCHANGERS OF UNCONVENTIONAL CHP UNITS

    Directory of Open Access Journals (Sweden)

    Peter Durcansky

    2015-08-01

    Full Text Available An unconventional CHP unit with a hot air engine is designed as the primary energy source with fuel in the form of biomass. The heat source is a furnace designed for combustion of biomass, whether in the form of wood logs or pellets. The transport of energy generated by the biomass combustion to the working medium of a hot-air engine is ensured by a special heat exchanger connected to this resource. The correct operation of the hot-air engine is largely dependent on an appropriate design of the exchanger. The paper deals with the calculation of the heat exchanger for the applicationsmentioned, using criterion equations, and based on CFD simulations.

  1. Molten carbonate fuel cells: A high temperature fuel cell on the edge to commercialization

    Science.gov (United States)

    Bischoff, Manfred

    The Molten Carbonate Fuel Cell (MCFC) technology has been developed in USA, Japan, Korea and Europe for many years. What has started about 30 years ago as an interesting laboratory object has now matured to a potential alternative to conventional power generation systems. Especially the combined heat and power (CHP) generation is an area, where MCFC power plants can be applied with great advantage, due to the high efficiencies which can be achieved. It was demonstrated by several manufacturers that in the sub-MW region MCFC power plants can reach electrical efficiencies of 47%. By making use of the heat generated by the system, total efficiencies of more than 80% can be achieved. The present paper will discuss some aspects of the development work going on with a focus on the role of the molten carbonate contained in the cells. An outlook will be given for the future prospects of this young technology in a changing energy market.

  2. Implications of the modelling of stratified hot water storage tanks in the simulation of CHP plants

    Energy Technology Data Exchange (ETDEWEB)

    Campos Celador, A., E-mail: alvaro.campos@ehu.es [ENEDI Research Group-University of the Basque Country, Departamento de Maquinas y Motores Termicos, E.T.S.I. de Bilbao Alameda de Urquijo, s/n 48013 Bilbao, Bizkaia (Spain); Odriozola, M.; Sala, J.M. [ENEDI Research Group-University of the Basque Country, Departamento de Maquinas y Motores Termicos, E.T.S.I. de Bilbao Alameda de Urquijo, s/n 48013 Bilbao, Bizkaia (Spain)

    2011-08-15

    Highlights: {yields} Three different modelling approaches for simulation of hot water tanks are presented. {yields} The three models are simulated within a residential cogeneration plant. {yields} Small differences in the results are found by an energy and exergy analysis. {yields} Big differences between the results are found by an advanced exergy analysis. {yields} Results on the feasibility study are explained by the advanced exergy analysis. - Abstract: This paper considers the effect that different hot water storage tank modelling approaches have on the global simulation of residential CHP plants as well as their impact on their economic feasibility. While a simplified assessment of the heat storage is usually considered in the feasibility studies of CHP plants in buildings, this paper deals with three different levels of modelling of the hot water tank: actual stratified model, ideal stratified model and fully mixed model. These three approaches are presented and comparatively evaluated under the same case of study, a cogeneration plant with thermal storage meeting the loads of an urbanisation located in the Bilbao metropolitan area (Spain). The case of study is simulated by TRNSYS for each one of the three modelling cases and the so obtained annual results are analysed from both a First and Second-Law-based viewpoint. While the global energy and exergy efficiencies of the plant for the three modelling cases agree quite well, important differences are found between the economic results of the feasibility study. These results can be predicted by means of an advanced exergy analysis of the storage tank considering the endogenous and exogenous exergy destruction terms caused by the hot water storage tank.

  3. Translation in cell-free systems

    International Nuclear Information System (INIS)

    The simplest, unambiguous identification of a particular mRNA is the identification of its protein product. This can be established by translation of the mRNA of interest in a cell-free protein-synthesizing system. Messenger RNA protein product identification is important in the isolation of a particular mRNA species for cDNA cloning and in the identification of positive cDNA clones. The two high-activity translation systems in common use are those prepared from rabbit reticulocytes and from wheat germ. Both systems are easy to prepare, and both are available commercially. Each has advantages and disadvantages over the other and a choice between the two will depend on the type of mRNAs to be translated, the prejudices of experience, and availability. The main disadvantage of the reticulocyte system is that it requires removal of endogenous mRNA. However, this is a relatively simple procedure. The wheat germ system does not require removal of endogenous mRNA and may translate weakly initiating mRNAs more efficiently. However, ionic optima for translation in the wheat germ system are more sensitive to the nature and concentration of mRNA and may need to be determined for each template. The biggest problem with the use of the wheat germ system is its tendency to produce incomplete translation products due to premature termination

  4. 1kW SOFC-CHP系统用催化燃烧耦合蒸汽重整反应器的实验研究%Experimental study on reactor integrating catalytic combustion and steam reforming for 1 kW SOFC-CHP

    Institute of Scientific and Technical Information of China (English)

    张莉; 邢耀华; 钟杰; 徐宏; 曹军

    2016-01-01

    针对1 kW固体氧化物燃料电池热电联供(SOFC-CHP)系统开发了集成催化燃烧、换热及蒸汽重整的反应器,搭建了性能评价系统,系统研究了燃烧侧气体组分及工艺参数对该反应器性能的影响规律。实验结果表明:在反应器燃烧侧气体入口温度为300℃、空燃比为10:1、电堆燃料利用率为65%、水碳比为3的条件下,重整侧转化率达到73.6%,重整尾气中H2含量为67.5%。电堆燃料利用率对重整反应转化效率影响较大,其值大于80%时,采用尾气燃烧的余热回收方式无法有效为蒸汽重整提供所需热量。在150~350℃范围内,降低燃烧侧气体入口温度对重整反应效率影响较小,建议采用尾气先换热再进行催化燃烧的流程设计,保证重整效率的前提下可有效提升系统热效率。空燃比的降低可小幅度提升重整效率,在保证电堆反应温度稳定的前提下,适当降低空燃比可减少空气压缩机的功耗,从而提升整个系统的效率。研究成果对SOFC-CHP系统的优化和整体效率提升具有指导意义。%A reactor integrating catalytic combustion, heat exchange and steam reforming was developed for a 1 kW solid oxide fuel cell-combined heating and power system (SOFC-CHP). Experiments were carried out to investigate the effect of combustion gas components and process parameters on properties of the reactor. The results showed that methane conversion rate was 73.6%and hydrogen concentration in the exhaust gas was 67.5%under operating conditions at the inlet temperature of combustion gas of 300℃, air-fuel ratio of 10:1, fuel utilization of stacks of 65% and water-carbon ratio of 3:1. Fuel utilization of the SOFC stacks had significant effect on methane conversion. Waste heat recovery from the exhaust gas combustion cannot provide enough heat for methane steam reforming when the fuel utilization was greater than 80%. Reduction of the inlet temperature

  5. Fuel processor for fuel cell power system

    Science.gov (United States)

    Vanderborgh, Nicholas E.; Springer, Thomas E.; Huff, James R.

    1987-01-01

    A catalytic organic fuel processing apparatus, which can be used in a fuel cell power system, contains within a housing a catalyst chamber, a variable speed fan, and a combustion chamber. Vaporized organic fuel is circulated by the fan past the combustion chamber with which it is in indirect heat exchange relationship. The heated vaporized organic fuel enters a catalyst bed where it is converted into a desired product such as hydrogen needed to power the fuel cell. During periods of high demand, air is injected upstream of the combustion chamber and organic fuel injection means to burn with some of the organic fuel on the outside of the combustion chamber, and thus be in direct heat exchange relation with the organic fuel going into the catalyst bed.

  6. Technical, economic and exergoeconomic assessment of small scale biomass CHP plant in an existing Brazilian's industry

    Energy Technology Data Exchange (ETDEWEB)

    Rodrigues, M.L.M.; Arrieta, F.R.P. [Papal Catholic University of Minas Gerais (PUC-Minas), Belo Horizonte, MG (Brazil). Dept. of Mechanical Engineering], Emails: mlmroduol.com.br, feliperp_arrieta@yahoo.com.br

    2009-07-01

    A technical, economic and exergoeconomic assessment was developed in order to verify the economic feasibility of the implementation of a CHP (Combined Heat and Power) plant in an existing Brazilian industry as a technological solution to assure the energy demands of its productive process. The assessment began with the attainment of the values of heat and electricity demands of the process. In a second stage, considering the current biomass availability and the existing boiler upgrade for the superheat steam generation, a small scale Rankine cycle was defined for the CHP plant. A thermodynamic model of the thermal cycle of CHP plant was crated in the EES (Engineering Equation Solver) and was used to simulating the interaction and integration with the production process and external interfaces. The simulation for the steady state operation considered the process values of heat and electricity demands considering two hypotheses: selling or not selling of electricity to the grid and burning wood chips or vegetal carbon residue as fuel. For the feasibility assessment, a cash flow was elaborated in a Microsoft Excel sheet and it was used for computing the conventional financial indicators of the CHP plant implementation: Net Present Value, Internal Rate of Return, and Pay Back. For the exergoeconomic assessment was applied the Thermo economic Structural Theory. The results show the mass, energy and entropy balances, as well as the characteristic parameters for the different equipment and the CCHP plant. The main conclusions are: there are not feasibility of the CHP plant implementation at the current electricity tariff and fuel price, but in a most favorable scenario the hypothesis of selling electricity to the grid was the most interesting among the assessed ones; the vegetal carbon residue is the fuel option with greater economic viability; the values of electricity cost calculated in the exergoeconomic analysis are coherent with the economic analysis ones and are

  7. Optimization of Fuel Cell System Operating Conditions for Fuel Cell Vehicles

    OpenAIRE

    Zhao, Hengbing; Burke, Andy

    2008-01-01

    Proton Exchange Membrane fuel cell (PEMFC) technology for use in fuel cell vehicles and other applications has been intensively developed in recent decades. Besides the fuel cell stack, air and fuel control and thermal and water management are major challenges in the development of the fuel cell for vehicle applications. The air supply system can have a major impact on overall system efficiency. In this paper a fuel cell system model for optimizing system operating conditions was developed wh...

  8. Flexible energy systems

    DEFF Research Database (Denmark)

    Lund, Henrik

    2003-01-01

    The paper discusses and analyses diffent national strategies and points out key changes in the energy system in order to achieve a system which can benefit from a high percentage of wind and CHP without having surplus production problems, introduced here as a flexible energy system....

  9. The capsid-coding region hairpin element (cHP) is a critical determinant of dengue virus and West Nile virus RNA synthesis

    OpenAIRE

    Clyde, Karen; Barrera, Julio; Harris, Eva

    2008-01-01

    Dengue virus (DENV) and West Nile virus (WNV) are members of the Flavivirus genus of positive-strand RNA viruses. RNA sequences and structures, primarily in the untranslated regions, have been shown to modulate flaviviral gene expression and genome replication. Previously, we demonstrated that a structure in the DENV coding region (cHP) enhances translation start codon selection and is required for viral replication. Here we further characterize the role of the cHP in the DENV life cycle. We ...

  10. Automated microscopy system for peripheral blood cells

    Science.gov (United States)

    Boev, Sergei F.; Sazonov, Vladimir V.; Kozinets, Gennady I.; Pogorelov, Valery M.; Gusev, Alexander A.; Korobova, Farida V.; Vinogradov, Alexander G.; Verdenskaya, Natalya V.; Ivanova, Irina A.

    2000-11-01

    The report describes the instrument ASPBS (Automated Screening of Peripheral Blood Cells) designed for an automated analysis of dry blood smears. The instrument is based on computer microscopy and uses dry blood smears prepared according to the standard Romanovskii-Giemza procedure. In comparison with the well-known flow cytometry systems, our instrument provides more detailed information and offers an opporunity of visualizing final results. The basic performances of the instrument are given. Software of this instrument is based on digital image processing and image recognition procedures. It is pointed out that the instrument can be used as a fairly universal tool in scientific research, public demonstrations, in medical treatment, and in medical education. The principle used as the basis of the instrument appeared adequate for creating an instrument version serviceable even during space flights where standard manual procedures and flow cytometry systems fail. The benefit of the use of the instrument in clinical laboratories is described.

  11. Phase Space Cell in Nonextensive Classical Systems

    Directory of Open Access Journals (Sweden)

    Piero Quarati

    2003-06-01

    Full Text Available Abstract: We calculate the phase space volume Ω occupied by a nonextensive system of N classical particles described by an equilibrium (or steady-state, or long-term stationary state of a nonequilibrium system distribution function, which slightly deviates from Maxwell-Boltzmann (MB distribution in the high energy tail. We explicitly require that the number of accessible microstates does not change respect to the extensive MB case. We also derive, within a classical scheme, an analytical expression of the elementary cell that can be seen as a macrocell, different from the third power of Planck constant. Thermodynamic quantities like entropy, chemical potential and free energy of a classical ideal gas, depending on elementary cell, are evaluated. Considering the fractional deviation from MB distribution we can deduce a physical meaning of the nonextensive parameter q of the Tsallis nonextensive thermostatistics in terms of particle correlation functions (valid at least in the case, discussed in this work, of small deviations from MB standard case.

  12. Status of commercial fuel cell powerplant system development

    Science.gov (United States)

    Warshay, Marvin

    The primary focus is on the development of commercial Phosphoric Acid Fuel Cell (PAFC) powerplant systems because the PAFC, which has undergone extensive development, is currently the closest fuel cell system to commercialization. Shorter discussions are included on the high temperature fuel cell systems which are not as mature in their development, such as the Molten Carbonate Fuel Cell (MCFC) and the Solid Oxide Fuel Cell (SOFC). The alkaline and the Solid Polymer Electrolyte (SPE) fuel cell systems, are also included, but their discussions are limited to their prospects for commercial development. Currently, although the alkaline fuel cell continues to be used for important space applications there are no commercial development programs of significant size in the USA and only small efforts outside. The market place for fuel cells and the status of fuel cell programs in the USA receive extensive treatment. The fuel cell efforts outside the USA, especially the large Japanese programs, are also discussed.

  13. Systems Biology for Organotypic Cell Cultures

    Energy Technology Data Exchange (ETDEWEB)

    Grego, Sonia [RTI International, Research Triangle Park, NC (United States); Dougherty, Edward R. [Texas A & M Univ., College Station, TX (United States); Alexander, Francis J. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Auerbach, Scott S. [National Inst. of Environmental Health Sciences, Research Triangle Park, NC (United States); Berridge, Brian R. [GlaxoSmithKline, Research Triangle Park, NC (United States); Bittner, Michael L. [Translational Genomics Research Inst., Phoenix, AZ (United States); Casey, Warren [National Inst. of Environmental Health Sciences, Research Triangle Park, NC (United States); Cooley, Philip C. [RTI International, Research Triangle Park, NC (United States); Dash, Ajit [HemoShear Therapeutics, Charlottesville, VA (United States); Ferguson, Stephen S. [National Inst. of Environmental Health Sciences, Research Triangle Park, NC (United States); Fennell, Timothy R. [RTI International, Research Triangle Park, NC (United States); Hawkins, Brian T. [RTI International, Research Triangle Park, NC (United States); Hickey, Anthony J. [RTI International, Research Triangle Park, NC (United States); Kleensang, Andre [Johns Hopkins Univ., Baltimore, MD (United States). Center for Alternatives to Animal Testing; Liebman, Michael N. [IPQ Analytics, Kennett Square, PA (United States); Martin, Florian [Phillip Morris International, Neuchatel (Switzerland); Maull, Elizabeth A. [National Inst. of Environmental Health Sciences, Research Triangle Park, NC (United States); Paragas, Jason [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Qiao, Guilin [Defense Threat Reduction Agency, Ft. Belvoir, VA (United States); Ramaiahgari, Sreenivasa [National Inst. of Environmental Health Sciences, Research Triangle Park, NC (United States); Sumner, Susan J. [RTI International, Research Triangle Park, NC (United States); Yoon, Miyoung [The Hamner Inst. for Health Sciences, Research Triangle Park, NC (United States); ScitoVation, Research Triangle Park, NC (United States)

    2016-08-04

    Translating in vitro biological data into actionable information related to human health holds the potential to improve disease treatment and risk assessment of chemical exposures. While genomics has identified regulatory pathways at the cellular level, translation to the organism level requires a multiscale approach accounting for intra-cellular regulation, inter-cellular interaction, and tissue/organ-level effects. Tissue-level effects can now be probed in vitro thanks to recently developed systems of three-dimensional (3D), multicellular, “organotypic” cell cultures, which mimic functional responses of living tissue. However, there remains a knowledge gap regarding interactions across different biological scales, complicating accurate prediction of health outcomes from molecular/genomic data and tissue responses. Systems biology aims at mathematical modeling of complex, non-linear biological systems. We propose to apply a systems biology approach to achieve a computational representation of tissue-level physiological responses by integrating empirical data derived from organotypic culture systems with computational models of intracellular pathways to better predict human responses. Successful implementation of this integrated approach will provide a powerful tool for faster, more accurate and cost-effective screening of potential toxicants and therapeutics. On September 11, 2015, an interdisciplinary group of scientists, engineers, and clinicians gathered for a workshop in Research Triangle Park, North Carolina, to discuss this ambitious goal. Participants represented laboratory-based and computational modeling approaches to pharmacology and toxicology, as well as the pharmaceutical industry, government, non-profits, and academia. Discussions focused on identifying critical system perturbations to model, the computational tools required, and the experimental approaches best suited to generating key data. This consensus report summarizes the discussions held.

  14. Lowering district heating temperatures – Impact to system performance in current and future Danish energy scenarios

    DEFF Research Database (Denmark)

    Ommen, Torben; Markussen, Wiebke Brix; Elmegaard, Brian

    2016-01-01

    CHP (Combined heat and power) production in connection with DH (district heating) systems has previously demonstrated a significant reduction in primary energy consumption. With extended installation of intermittent sustainable sources, such as eg. wind turbines rather than thermal units, the cha......CHP (Combined heat and power) production in connection with DH (district heating) systems has previously demonstrated a significant reduction in primary energy consumption. With extended installation of intermittent sustainable sources, such as eg. wind turbines rather than thermal units...

  15. Drug delivery system and breast cancer cells

    Science.gov (United States)

    Colone, Marisa; Kaliappan, Subramanian; Calcabrini, Annarica; Tortora, Mariarosaria; Cavalieri, Francesca; Stringaro, Annarita

    2016-06-01

    Recently, nanomedicine has received increasing attention for its ability to improve the efficacy of cancer therapeutics. Nanosized polymer therapeutic agents offer the advantage of prolonged circulation in the blood stream, targeting to specific sites, improved efficacy and reduced side effects. In this way, local, controlled delivery of the drug will be achieved with the advantage of a high concentration of drug release at the target site while keeping the systemic concentration of the drug low, thus reducing side effects due to bioaccumulation. Various drug delivery systems such as nanoparticles, liposomes, microparticles and implants have been demonstrated to significantly enhance the preventive/therapeutic efficacy of many drugs by increasing their bioavailability and targetability. As these carriers significantly increase the therapeutic effect of drugs, their administration would become less cost effective in the near future. The purpose of our research work is to develop a delivery system for breast cancer cells using a microvector of drugs. These results highlight the potential uses of these responsive platforms suited for biomedical and pharmaceutical applications. At the request of all authors of the paper an updated version was published on 12 July 2016. The manuscript was prepared and submitted without Dr. Francesca Cavalieri's contribution and her name was added without her consent. Her name has been removed in the updated and re-published article.

  16. Hybrid regenerative fuel cell systems for space applications

    Science.gov (United States)

    Saucier, David R.

    1988-01-01

    This paper describes a hybrid regenerative fuel cell (RFC) system for space application, which is made up of an alkaline fuel cell (Space Shuttle fuel cell) and an acid electrolysis unit (solid polymer electrolyte). In the RFC, gas produced from the acid electrolysis unit and water produced by the alkaline fuel cell are repeatedly reacted in the other unit. The results of RFC's tests indicate that the system is feasible in terms of fluid/unit compatibility. In addition, the fuel cell thermal-control system proved capable of controlling fuel cell temperatures throughout long open-circuit periods. Diagrams of the RFC and its subsystems are included.

  17. Woking Park PAFC CHP monitoring. Phase 1: Planning, installation and commissioning

    Energy Technology Data Exchange (ETDEWEB)

    Goulding, P.S.; Fry, M.R.

    2003-07-01

    This report covers the planning, installation and commissioning of the first commercially operated fuel cell cogeneration system in the UK. The involvement of Woking Borough Council, its approach to energy efficiency, and the Woking Park site are discussed, and details are given of the PC25/C 200kW fuel cell which is manufactured in the US by UTC Fuel Cells. A description of the Woking Park fuel cell combined heat and power application is presented, and the project economics, specification and tendering are examined. The route taken to planning approval is traced, and installation procedures are outlined. The testing of the phosphoric type PC25 fuel cell cogeneration unit is described, and expected cost and project timescales are noted.

  18. Simplified Load-Following Control for a Fuel Cell System

    Science.gov (United States)

    Vasquez, Arturo

    2010-01-01

    A simplified load-following control scheme has been proposed for a fuel cell power system. The scheme could be used to control devices that are important parts of a fuel cell system but are sometimes characterized as parasitic because they consume some of the power generated by the fuel cells.

  19. Small scale combined heat and power (CHP) from bio-crude oil fuelled to a sterling engine (Bio-stir)

    Energy Technology Data Exchange (ETDEWEB)

    Gyftopoulou, M.; Papamichael, I.; Boukis, I. [Centre for Renewable Energy Sources, Pikermi (Greece)

    2002-02-01

    De-coupling of biomass conversion and combined heat and power (CHP) production may be best achieved by a liquid fuel, namely Bio-Crude-Oil (BCO), derived by fast pyrolysis of biomass. BCO can be fuelled in a modified Stirling engine, which is able to provide a high electrical efficiency (approximately 30%) and a favourable overall efficiency (approximately 80% on CHP), which is extremely important for economic viability in small-scale (< 100 kW{sub e}). The external combustion employed in the Stirling engine enables the utilisation of relatively 'dirty' fuels such as BCO. On the aforementioned grounds, a project was drawn, aiming to accomplish the following objectives: Development of feedstock logistics for BCO production via fast pyrolysis technology; Testing of different feedstocks for BCO production and feedstock characterisation, fast pyrolysis reactor extensive operation - process optimisation, as well as BCO characterisation; Evaluation of the scale-up potential of the biomass fast pyrolysis technology; Development of a suitable burner for BCO combustion and adaptation of a Stirling engine to be fuelled with BCO; Techno-economic assessment of the proposed, entire biomass-to-energy route, including Life Cycle Assessment (LCA); Investigation for the industrial exploitation of the technology including scale-up and small-scale CHP deployment. The project has resulted in the following industrial benefits: Assessment for the production and logistics of the selected feedstocks (i.e. pine and miscanthus) for BCO production; Adoption of measures to deal with major technical risks associated with industrial scale-up (in particular char and particulates removal and vapour quenching); Assessment of the scale-up potential of the fast pyrolysis technology (in the range of 5 to 25 MW{sub th}). Demonstration of BCO combustion in a modified Stirling engine; Evaluation of the Stirling engine performance in terms of efficiency and emissions; Assessment of the

  20. Systemic adjuvant therapies in renal cell carcinoma.

    Science.gov (United States)

    Buti, Sebastiano; Bersanelli, Melissa; Donini, Maddalena; Ardizzoni, Andrea

    2012-10-01

    Renal cell carcinoma (RCC) is one of the ten most frequent solid tumors worldwide. Recent innovations in the treatment of metastatic disease have led to new therapeutic approaches being investigated in the adjuvant setting. Observation is the only current standard of care after radical nephrectomy, although there is evidence of efficacy of adjuvant use of vaccine among all the strategies used. This article aims to collect published experiences with systemic adjuvant approaches in RCC and to describe the results of past and ongoing phase III clinical trials in this field. We explored all the systemic treatments, including chemotherapy, immunotherapy and targeted drugs while alternative approaches have also been described. Appropriate selection of patients who would benefit from adjuvant therapies remains a crucial dilemma. Although the international guidelines do not actually recommend any adjuvant treatment after radical surgery for RCC, no conclusions have yet been drawn pending the results of the promising ongoing clinical trials with the target therapies. The significant changes that these new drugs have made on advanced disease outcome could represent the key to innovation in terms of preventing recurrence, delaying relapse and prolonging survival after radical surgery for RCC. PMID:25992216

  1. Systemic adjuvant therapies in renal cell carcinoma

    Directory of Open Access Journals (Sweden)

    Sebastiano Buti

    2012-10-01

    Full Text Available Renal cell carcinoma (RCC is one of the ten most frequent solid tumors worldwide. Recent innovations in the treatment of metastatic disease have led to new therapeutic approaches being investigated in the adjuvant setting. Observation is the only current standard of care after radical nephrectomy, although there is evidence of efficacy of adjuvant use of vaccine among all the strategies used. This article aims to collect published experiences with systemic adjuvant approaches in RCC and to describe the results of past and ongoing phase III clinical trials in this field. We explored all the systemic treatments, including chemotherapy, immunotherapy and targeted drugs while alternative approaches have also been described. Appropriate selection of patients who would benefit from adjuvant therapies remains a crucial dilemma. Although the international guidelines do not actually recommend any adjuvant treatment after radical surgery for RCC, no conclusions have yet been drawn pending the results of the promising ongoing clinical trials with the target therapies. The significant changes that these new drugs have made on advanced disease outcome could represent the key to innovation in terms of preventing recurrence, delaying relapse and prolonging survival after radical surgery for RCC.

  2. CHP HIGHER EDUCATION, SCHOLARSHIPS AND DEMAND ABROAD ARE POLITICS (1942-1947

    Directory of Open Access Journals (Sweden)

    Suat ZEYREK

    2016-04-01

    Full Text Available Turkey was followed by a very slow development in the course of the republic’s first year in higher education.By 1955, there are only two universities in the three cities in Turkey.Although the new university will be declared opened by Ismet Inonu’s mouth several times it was not possible for various reasons.Turkey’s economic situation, the shortage of trained personel and it has been hampered by severe conditions of World War II.But even more important excuses should have prevented the spread of higher education in Turkey. This article will be presented in the light of the real causes of the problem of archival sources mentioned above.Period ruling party, the CHP’s higher education policy followed in scholarships and dormitories were investigated.CHP likely to promote higher education in the first primary education spread to the base and thus wants to create a higher demand.For this reason, it is necessary first of all to build infrastructure for higher education institutions and rules.Coming from big cities in different regions of Anatolia youth to take education to all students experience difficulties and inclusive, egalitarian policies were followed.

  3. Implementation strategy for small CHP-plants in a competitive market: the case of Lithuania

    Energy Technology Data Exchange (ETDEWEB)

    Lund, H. [Aalborg Univ., Dept. of Development and Planning, Aalborg (Denmark); Siupsinskas, G.; Martinaitis, V. [Vilnius Gediminas Technical Univ., Dept. of Heating and Ventilation, Vilnius (Lithuania)

    2005-11-01

    Within five years from now, Lithuania is going to close down Ignalina, the only nuclear-power plant in the country. Since Ignalina generates more than 75% of the Lithuanian electricity production, new generation capacities are needed. Traditional steam-turbines, fuelled with fossil fuels, would mean further imports of fuel as well as a rise in CO{sub 2} emissions. At the same time, several small district-heating companies one suffering from high heating-prices. Typically, the price in small towns is 20-50% higher than the price in large urban areas. Consequently, alternative strategies should be considered. This article analyses the conditions for one such strategy, namely the replacement of boilers in the existing district-heating supplies with combined heat-and-power production (CHP). Compared with new power stations, fuel can be saved and CO{sub 2}-emissions reduced. Also this strategy can be used to level the difference between low heating prices in the large urban areas and high prices in small towns and villages. (Author)

  4. Hydrocarbon emissions from gas engine CHP-units. 2011 measurement program

    Energy Technology Data Exchange (ETDEWEB)

    Van Dijk, G.H.J. [KEMA, Arnhem (Netherlands)

    2012-06-15

    In December 2009, the Ministry of Infrastructure and Environment (IandM) issued the Decree on Emission Limits for Middle Sized Combustion Installations (BEMS). This decree imposes a first-time emission limit value (ELV) of 1500 mg C/m{sup 3}{sub o} at 3% O{sub 2} for hydrocarbons emitted by gas engines. IandM used the findings of two hydrocarbon emission measurement programs, executed in 2007 and 2009, as a guideline for this initial ELV. The programs did reveal substantial variation in the hydrocarbon emissions of the gas engines tested. This variation, and especially the uncertainty as to the role of engine and/or other parameters causing such variation, was felt to hamper further policy development. IandM therefore commissioned KEMA to perform follow-up measurements on ten gas engine CHP-units in 2011. Aim of this 2011 program is to assess hydrocarbon emission variation in relation to engine parameters and process conditions including maintenance status, and to atmospheric conditions. The 2011 program comprised two identical measurement sessions, one in spring and one in winter.

  5. Robust Management of Combined Heat and Power Systems via Linear Decision Rules

    DEFF Research Database (Denmark)

    Zugno, Marco; Morales González, Juan Miguel; Madsen, Henrik

    2014-01-01

    The heat and power outputs of Combined Heat and Power (CHP) units are jointly constrained. Hence, the optimal management of systems including CHP units is a multicommodity optimization problem. Problems of this type are stochastic, owing to the uncertainty inherent both in the demand for heat...... and in the electricity prices that owners of CHP units receive for the power they sell in the market. In this work, we model the management problem for a coupled heat-and-power system comprising CHP plants, units solely producing heat as well as heat storages. We propose a robust optimization model including unit...... commitment, day-ahead power and heat dispatch as well as real-time re-dispatch (recourse) variables. This model yields a solution that is feasible under any realization of the heat demand within a given uncertainty set. Optimal recourse functions for the real-time operation of the units are approximated via...

  6. Stem cells in the nervous system.

    Science.gov (United States)

    Maldonado-Soto, Angel R; Oakley, Derek H; Wichterle, Hynek; Stein, Joel; Doetsch, Fiona K; Henderson, Christopher E

    2014-11-01

    Given their capacity to regenerate cells lost through injury or disease, stem cells offer new vistas into possible treatments for degenerative diseases and their underlying causes. As such, stem cell biology is emerging as a driving force behind many studies in regenerative medicine. This review focuses on the current understanding of the applications of stem cells in treating ailments of the human brain, with an emphasis on neurodegenerative diseases. Two types of neural stem cells are discussed: endogenous neural stem cells residing within the adult brain and pluripotent stem cells capable of forming neural cells in culture. Endogenous neural stem cells give rise to neurons throughout life, but they are restricted to specialized regions in the brain. Elucidating the molecular mechanisms regulating these cells is key in determining their therapeutic potential as well as finding mechanisms to activate dormant stem cells outside these specialized microdomains. In parallel, patient-derived stem cells can be used to generate neural cells in culture, providing new tools for disease modeling, drug testing, and cell-based therapies. Turning these technologies into viable treatments will require the integration of basic science with clinical skills in rehabilitation.

  7. A novel multilayer immunoisolating encapsulation system overcoming protrusion of cells

    NARCIS (Netherlands)

    Bhujbal, Swapnil V.; de Haan, Bart; Niclou, Simone P.; de Vos, Paul

    2014-01-01

    Application of alginate-microencapsulated therapeutic cells is a promising approach for diseases that require a local and constant supply of therapeutic molecules. However most conventional alginate microencapsulation systems are associated with low mechanical stability and protrusion of cells which

  8. Design and Control of High Temperature PEM Fuel Cell System

    DEFF Research Database (Denmark)

    Andreasen, Søren Juhl

    E-cient fuel cell systems have started to appear in many dierent commercial applications and large scale production facilities are already operating to supply fuel cells to support an ever growing market. Fuel cells are typically considered to replace leadacid batteries in applications where...... or life time losses. In order to evaluate the performance of using HTPEM fuel cells for electricity production in electrical applications, a 400 W fuel cell system is initially designed using a cathode air cooled 30 cell HTPEM stack. The stack runs on pure hydrogen in a deadend anode configuration...... that often during a normal driving cycle. The combination of batteries and super capacitors together with fuel cells can improve the system performance, lifetime and cost. Simple systems can be designed where the fuel cells and batteries are directly connected, but the introduction of power electronics can...

  9. Stem cell biology meets systems biology

    OpenAIRE

    Roeder, I.; Radtke, F.

    2009-01-01

    Stem cells and their descendents are the building blocks of life. How stem cell populations guarantee their maintenance and/or self-renewal, and how individual stem cells decide to transit from one cell stage to another to generate different cell types are long-standing and fascinating questions in the field. Here, we review the discussions that took place at a recent EMBO conference in Cambridge, UK, in which these questions were placed in the context of the latest advances in stem cell biol...

  10. Aging and the Dendritic Cell System: Implications for Cancer

    OpenAIRE

    Shurin, Michael R.; Shurin, Galina V.; Chatta, Gurkamal S.

    2007-01-01

    The immune system shows a decline in responsiveness to antigens both with aging, as well as in the presence of tumors. The malfunction of the immune system with age can be attributed to developmental and functional alterations in several cell populations. Previous studies have shown defects in humoral responses and abnormalities in T cell function in aged individuals, but have not distinguished between abnormalities in antigen presentation and intrinsic T cell or B cell defects in aged indivi...

  11. Physics of cell adhesion: some lessons from cell-mimetic systems

    OpenAIRE

    Sackmann, Erich; Smith, Ana-Sunčana

    2014-01-01

    Cell adhesion is a paradigm of the ubiquitous interplay of cell signalling, modulation of material properties and biological functions of cells. It is controlled by competition of short range attractive forces, medium range repellant forces and the elastic stresses associated with local and global deformation of the composite cell envelopes. We review the basic physical rules governing the physics of cell adhesion learned by studying cell-mimetic systems and demonstrate the importance of thes...

  12. Comparison of defined culture systems for feeder cell free propagation of human embryonic stem cells

    OpenAIRE

    Akopian, Veronika; Andrews, Peter W.; Beil, Stephen; Benvenisty, Nissim; Brehm, Jennifer; Christie, Megan; Ford, Angela; Fox, Victoria; Gokhale, Paul J; Healy, Lyn; Holm, Frida; Hovatta, Outi; Knowles, Barbara B; Ludwig, Tenneille E; Ronald D G McKay

    2010-01-01

    There are many reports of defined culture systems for the propagation of human embryonic stem cells in the absence of feeder cell support, but no previous study has undertaken a multi-laboratory comparison of these diverse methodologies. In this study, five separate laboratories, each with experience in human embryonic stem cell culture, used a panel of ten embryonic stem cell lines (including WA09 as an index cell line common to all laboratories) to assess eight cell culture methods, with pr...

  13. Energy Saving and GHG Emission Reduction in a Micro-CCHP System by Use of Solar Energy

    OpenAIRE

    ION, I.; Ciocea, G; Popescu, F

    2012-01-01

    In this work, the reduction of greenhouse gas emission, and the energy saving by integrating solar collectors and photovoltaic panels in a Stirling engine based microcombined cooling, heating and power (mCCHP) system are studied. The mCCHP system consists of a natural gas Stirling CHP and an adsorber chiller. When the thermal outputs of the Stirling CHP and solar collectors are not sufficient to cover the heat demand for domestic hot water (DHW), heating/cooling, an au...

  14. System-level design of bacterial cell cycle control

    OpenAIRE

    McAdams, Harley H.; Shapiro, Lucy

    2009-01-01

    Understanding of the cell cycle control logic in Caulobacter has progressed to the point where we now have an integrated view of the operation of an entire bacterial cell cycle system functioning as a state machine. Oscillating levels of a few temporally-controlled master regulator proteins in a cyclical circuit drive cell cycle progression. To a striking degree, the cell cycle regulation is a whole cell phenomenon. Phospho-signaling proteins and proteases dynamically deployed to specific loc...

  15. T cells and the humoral immune system

    NARCIS (Netherlands)

    W.B. van Muiswinkel (Willem)

    1975-01-01

    textabstractLymphoid cells and macrophages play an important role in the development and rnaintance of humoral and cellular immunity in mammals. The lymphoid cells in the peripheral lymphoid organs are divided into two major classes: (1) thymus-derived lymphocytes or T cells and (2) bursa-equivalent

  16. An assessment of the present and future opportunities for combined heat and power with district heating (CHP-DH) in the United Kingdom

    International Nuclear Information System (INIS)

    As global fuel reserves are depleted, alternative and more efficient forms of energy generation and delivery will be required. Combined heat and power with district heating (CHP-DH) provides an alternative energy production and delivery mechanism that is less resource intensive, more efficient and provides greater energy security than many popular alternatives. It will be shown that the economic viability of CHP-DH networks depends on several principles, namely (1) the optimisation of engineering and design principles; (2) organisational and regulatory frameworks; (3) financial and economic factors. It was found that in the long term DH is competitive with other energy supply and distribution technologies such as electricity and gas. However, in the short to medium term it is shown that economic risk, regulatory uncertainty and lock-in of existing technology are the most significant barriers to CHP-DH development. This research suggests that under the present regulatory and economic paradigm, the infrastructure required for DH networks remains financially prohibitive; the implementation of government policies are complicated and impose high transaction costs, while engineering solutions are frequently not implemented or economically optimised. If CHP-DH is going to play any part in meeting climate change targets then collaboration between public and private organisations will be required. It is clear from this analysis that strong local government involvement is therefore necessary for the co-ordination, leadership and infrastructural deployment of CHP-DH.

  17. Cell fate control in the developing central nervous system

    Energy Technology Data Exchange (ETDEWEB)

    Guérout, Nicolas; Li, Xiaofei; Barnabé-Heider, Fanie, E-mail: Fanie.Barnabe-Heider@ki.se

    2014-02-01

    The principal neural cell types forming the mature central nervous system (CNS) are now understood to be diverse. This cellular subtype diversity originates to a large extent from the specification of the earlier proliferating progenitor populations during development. Here, we review the processes governing the differentiation of a common neuroepithelial cell progenitor pool into mature neurons, astrocytes, oligodendrocytes, ependymal cells and adult stem cells. We focus on studies performed in mice and involving two distinct CNS structures: the spinal cord and the cerebral cortex. Understanding the origin, specification and developmental regulators of neural cells will ultimately impact comprehension and treatments of neurological disorders and diseases. - Highlights: • Similar mechanisms regulate cell fate in different CNS cell types and structures. • Cell fate regulators operate in a spatial–temporal manner. • Different neural cell types rely on the generation of a diversity of progenitor cells. • Cell fate decision is dictated by the integration of intrinsic and extrinsic signals.

  18. Maintenance of the cell morphology by MinC in Helicobacter pylori.

    Directory of Open Access Journals (Sweden)

    Pei-Yu Chiou

    Full Text Available In the model organism Escherichia coli, Min proteins are involved in regulating the division of septa formation. The computational genome analysis of Helicobacter pylori, a gram-negative microaerophilic bacterium causing gastritis and peptic ulceration, also identified MinC, MinD, and MinE. However, MinC (HP1053 shares a low identity with those of other bacteria and its function in H. pylori remains unclear. In this study, we used morphological and genetic approaches to examine the molecular role of MinC. The results were shown that an H. pylori mutant lacking MinC forms filamentous cells, while the wild-type strain retains the shape of short rods. In addition, a minC mutant regains the short rods when complemented with an intact minCHp gene. The overexpression of MinCHp in E. coli did not affect the growth and cell morphology. Immunofluorescence microscopy revealed that MinCHp forms helix-form structures in H. pylori, whereas MinCHp localizes at cell poles and pole of new daughter cell in E. coli. In addition, co-immunoprecipitation showed MinC can interact with MinD but not with FtsZ during mid-exponential stage of H. pylori. Altogether, our results show that MinCHp plays a key role in maintaining proper cell morphology and its function differs from those of MinCEc.

  19. Advanced Fuel Cell System Thermal Management for NASA Exploration Missions

    Science.gov (United States)

    Burke, Kenneth A.

    2009-01-01

    The NASA Glenn Research Center is developing advanced passive thermal management technology to reduce the mass and improve the reliability of space fuel cell systems for the NASA exploration program. An analysis of a state-of-the-art fuel cell cooling systems was done to benchmark the portion of a fuel cell system s mass that is dedicated to thermal management. Additional analysis was done to determine the key performance targets of the advanced passive thermal management technology that would substantially reduce fuel cell system mass.

  20. Cost Analysis of Fuel Cell Systems for Transportation Compressed Hydrogen and PEM Fuel Cell System

    Energy Technology Data Exchange (ETDEWEB)

    Eric J. Carlson

    2004-10-20

    PEMFC technology for transportation must be competitive with internal combustion engine powertrains in a number of key metrics, including performance, life, reliability, and cost. Demonstration of PEMFC cost competitiveness has its own challenges because the technology has not been applied to high volume automotive markets. The key stack materials including membranes, electrodes, bipolar plates, and gas diffusion layers have not been produced in automotive volumes to the exacting quality requirements that will be needed for high stack yields and to the evolving property specifications of high performance automotive stacks. Additionally, balance-of-plant components for air, water, and thermal management are being developed to meet the unique requirements of fuel cell systems. To address the question of whether fuel cells will be cost competitive in automotive markets, the DOE has funded this project to assess the high volume production cost of PEM fuel cell systems. In this report a historical perspective of our efforts in assessment of PEMFC cost for DOE is provided along with a more in-depth assessment of the cost of compressed hydrogen storage is provided. Additionally, the hydrogen storage costs were incorporated into a system cost update for 2004. Assessment of cost involves understanding not only material and production costs, but also critical performance metrics, i.e., stack power density and associated catalyst loadings that scale the system components. We will discuss the factors influencing the selection of the system specification (i.e., efficiency, reformate versus direct hydrogen, and power output) and how these have evolved over time. The reported costs reflect internal estimates and feedback from component developers and the car companies. Uncertainty in the cost projection was addressed through sensitivity analyses.

  1. Cell viability and repair systems in mammal cells

    International Nuclear Information System (INIS)

    Synchronized cell cultures of mice are irradiated with 4,0J/m2 ultraviolet light at different times. The possible mechanisms involved in the recuperation of the cellular survival observed, are discussed. (M.A.)

  2. Economics of Direct Hydrogen Polymer Electrolyte Membrane Fuel Cell Systems

    Energy Technology Data Exchange (ETDEWEB)

    Mahadevan, Kathyayani

    2011-10-04

    Battelle's Economic Analysis of PEM Fuel Cell Systems project was initiated in 2003 to evaluate the technology and markets that are near-term and potentially could support the transition to fuel cells in automotive markets. The objective of Battelle?s project was to assist the DOE in developing fuel cell systems for pre-automotive applications by analyzing the technical, economic, and market drivers of direct hydrogen PEM fuel cell adoption. The project was executed over a 6-year period (2003 to 2010) and a variety of analyses were completed in that period. The analyses presented in the final report include: Commercialization scenarios for stationary generation through 2015 (2004); Stakeholder feedback on technology status and performance status of fuel cell systems (2004); Development of manufacturing costs of stationary PEM fuel cell systems for backup power markets (2004); Identification of near-term and mid-term markets for PEM fuel cells (2006); Development of the value proposition and market opportunity of PEM fuel cells in near-term markets by assessing the lifecycle cost of PEM fuel cells as compared to conventional alternatives used in the marketplace and modeling market penetration (2006); Development of the value proposition of PEM fuel cells in government markets (2007); Development of the value proposition and opportunity for large fuel cell system application at data centers and wastewater treatment plants (2008); Update of the manufacturing costs of PEM fuel cells for backup power applications (2009).

  3. A Total Cost of Ownership Model for Low Temperature PEM Fuel Cells in Combined Heat and Power and Backup Power Applications

    Energy Technology Data Exchange (ETDEWEB)

    University of California, Berkeley; Wei, Max; Lipman, Timothy; Mayyas, Ahmad; Chien, Joshua; Chan, Shuk Han; Gosselin, David; Breunig, Hanna; Stadler, Michael; McKone, Thomas; Beattie, Paul; Chong, Patricia; Colella, Whitney; James, Brian

    2014-06-23

    A total cost of ownership model is described for low temperature proton exchange membrane stationary fuel cell systems for combined heat and power (CHP) applications from 1-250kW and backup power applications from 1-50kW. System designs and functional specifications for these two applications were developed across the range of system power levels. Bottom-up cost estimates were made for balance of plant costs, and detailed direct cost estimates for key fuel cell stack components were derived using design-for-manufacturing-and-assembly techniques. The development of high throughput, automated processes achieving high yield are projected to reduce the cost for fuel cell stacks to the $300/kW level at an annual production volume of 100 MW. Several promising combinations of building types and geographical location in the U.S. were identified for installation of fuel cell CHP systems based on the LBNL modelling tool DER CAM. Life-cycle modelling and externality assessment were done for hotels and hospitals. Reduced electricity demand charges, heating credits and carbon credits can reduce the effective cost of electricity ($/kWhe) by 26-44percent in locations such as Minneapolis, where high carbon intensity electricity from the grid is displaces by a fuel cell system operating on reformate fuel. This project extends the scope of existing cost studies to include externalities and ancillary financial benefits and thus provides a more comprehensive picture of fuel cell system benefits, consistent with a policy and incentive environment that increasingly values these ancillary benefits. The project provides a critical, new modelling capacity and should aid a broad range of policy makers in assessing the integrated costs and benefits of fuel cell systems versus other distributed generation technologies.

  4. Single cell deposition and patterning with a robotic system.

    Directory of Open Access Journals (Sweden)

    Zhe Lu

    Full Text Available Integrating single-cell manipulation techniques in traditional and emerging biological culture systems is challenging. Microfabricated devices for single cell studies in particular often require cells to be spatially positioned at specific culture sites on the device surface. This paper presents a robotic micromanipulation system for pick-and-place positioning of single cells. By integrating computer vision and motion control algorithms, the system visually tracks a cell in real time and controls multiple positioning devices simultaneously to accurately pick up a single cell, transfer it to a desired substrate, and deposit it at a specified location. A traditional glass micropipette is used, and whole- and partial-cell aspiration techniques are investigated to manipulate single cells. Partially aspirating cells resulted in an operation speed of 15 seconds per cell and a 95% success rate. In contrast, the whole-cell aspiration method required 30 seconds per cell and achieved a success rate of 80%. The broad applicability of this robotic manipulation technique is demonstrated using multiple cell types on traditional substrates and on open-top microfabricated devices, without requiring modifications to device designs. Furthermore, we used this serial deposition process in conjunction with an established parallel cell manipulation technique to improve the efficiency of single cell capture from ∼80% to 100%. Using a robotic micromanipulation system to position single cells on a substrate is demonstrated as an effective stand-alone or bolstering technology for single-cell studies, eliminating some of the drawbacks associated with standard single-cell handling and manipulation techniques.

  5. Structure and function of stem cell pools in mammalian cell renewal systems

    International Nuclear Information System (INIS)

    Stem cells play a key-role in the maintenance of the equilibrium between cell loss and cell production in cell renewal systems as well as in the understanding of the radiation pathophysiology of mammalian organisms. The integrity of mammalian organisms with the need to maintain a constant ''millieu interior'' is depending on the normal functioning of cell renewal systems, especially those of epithelial surfaces and blood cell forming organs. All cell renewal systems of bodies have a very similar functional structure consisting of functional, proliferative - amplifying and stem cell compartments. They differ in transit and cell cycle times and in the number of amplification division - aside from the difference in their functional and biochemical make-up. The stem cell pools are providing the cells capable of differentiation without depleting their own kind. This can be achieved by symmetrical or assymmetrical stem cell division. In normal steady state, 50% of the stem cell division remain in the stem cell pool, while the other 50% leave it to differentiate, proliferate and mature, hemopoietic system is distributed throughout bodies. This is an important factor in the radiation biology of mammalian organisms since the loss of function in one area can be compensated for by more production in other areas, and locally depleted sites can be reseeded with the stem cells migrating in from blood. (Yamashita, S.)

  6. 小规模热电联供(CHP)技术的特点及发展前景%Features of small-scale combined heat and power (CHP) technology and its development prospects

    Institute of Scientific and Technical Information of China (English)

    张颖颖; 曹广益; 朱新坚

    2005-01-01

    介绍了几种小规模热电联供(combined heat and power,简称CHP)技术(往复式发动机、微型涡轮机、史特林发动机、燃料电池)的特点.分析了影响小规模CHP技术发展的有利和不利因素.对目前世界范围内的小规模CHP技术的发展前景进行了展望,并就我国开展小规模CHP技术研究提出了建议.

  7. Cell death in the cardiovascular system

    OpenAIRE

    Clarke, Murray; Bennett, Martin; Littlewood, Trevor

    2006-01-01

    Cell death is important for both development and tissue homeostasis in the adult. As such, it is tightly controlled and deregulation is associated with diverse pathologies; for example, regulated cell death is involved in vessel remodelling during development or following injury, but deregulated death is implicated in pathologies such as atherosclerosis, aneurysm formation, ischaemic and dilated cardiomyopathies and infarction. We describe the mechanisms of cell death and its role in the norm...

  8. Measuring cell identity in noisy biological systems

    OpenAIRE

    Birnbaum, Kenneth D; Kussell, Edo

    2011-01-01

    Global gene expression measurements are increasingly obtained as a function of cell type, spatial position within a tissue and other biologically meaningful coordinates. Such data should enable quantitative analysis of the cell-type specificity of gene expression, but such analyses can often be confounded by the presence of noise. We introduce a specificity measure Spec that quantifies the information in a gene's complete expression profile regarding any given cell type, and an uncertainty me...

  9. Design of gasifiers to optimize fuel cell systems

    Energy Technology Data Exchange (ETDEWEB)

    1992-02-01

    The objective of this project is to configure coal gasification/carbonate fuel cell systems that can significantly improve the economics, performance, and efficiency of electric power generation systems. (VC)

  10. Advances in Materials and System Technology for Portable Fuel Cells

    Science.gov (United States)

    Narayanan, Sekharipuram R.

    2007-01-01

    This viewgraph presentation describes the materials and systems engineering used for portable fuel cells. The contents include: 1) Portable Power; 2) Technology Solution; 3) Portable Hydrogen Systems; 4) Direct Methanol Fuel Cell; 5) Direct Methanol Fuel Cell System Concept; 6) Overview of DMFC R&D at JPL; 7) 300-Watt Portable Fuel Cell for Army Applications; 8) DMFC units from Smart Fuel Cell Inc, Germany; 9) DMFC Status and Prospects; 10) Challenges; 11) Rapid Screening of Well-Controlled Catalyst Compositions; 12) Screening of Ni-Zr-Pt-Ru alloys; 13) Issues with New Membranes; 14) Membranes With Reduced Methanol Crossover; 15) Stacks; 16) Hybrid DMFC System; 17) Small Compact Systems; 18) Durability; and 19) Stack and System Parameters for Various Applications.

  11. Neuronal chemokines : Versatile messengers in central nervous system cell interaction

    NARCIS (Netherlands)

    de Haas, A. H.; van Weering, H. R. J.; de Jong, E. K.; Boddeke, H. W. G. M.; Biber, K. P. H.

    2007-01-01

    Whereas chemokines are well known for their ability to induce cell migration, only recently it became evident that chemokines also control a variety of other cell functions and are versatile messengers in the interaction between a diversity of cell types. In the central nervous system (CNS), chemoki

  12. Investigation of a novel heat pipe solar collector/CHP system

    OpenAIRE

    Zhao, Xudong

    2003-01-01

    The European Union has an ongoing commitment to reducing CO2 emission as highlighted by its agreement at the Kyoto Summit. One approach to achieving these reductions would be to develop alternative energy sources for major energy demanding sectors. In the EU, about 40% of all energy consumed is associated with buildings and of this, about 60% is utilised in the housing sector. A major part of the energy demand of buildings could be met by utilising renewable energy sources, e.g. solar energy....

  13. Cell-to-cell variability in cell death: can systems biology help us make sense of it all?

    OpenAIRE

    Xia, X; Owen, M. S.; Lee, R E C; Gaudet, S

    2014-01-01

    One of the most common observations in cell death assays is that not all cells die at the same time, or at the same treatment dose. Here, using the perspective of the systems biology of apoptosis and the context of cancer treatment, we discuss possible sources of this cell-to-cell variability as well as its implications for quantitative measurements and computational models of cell death. Many different factors, both within and outside of the apoptosis signaling networks, have been correlated...

  14. The CHP, The U.S., and Ulus: the portrayal of the United States in Ulus Gazetesi during WWII

    OpenAIRE

    Mc Connel, Adam Bennett

    2008-01-01

    Traditional accounts of Turkish-American relations point to the 1945-1947 period as the point at which political ties between the two countries became "important." However, when one looks at the information about the United States published by Ulus Gazetesi, the semi-official newspaper of the CHP, during that period, one sees a fully-developed pro-U.S. perspective, complete with many articles directly translated from U.S. sources. From this situation, we can infer that the Turkish-American ...

  15. Air intake and exhaust systems in fuel cell engines

    Energy Technology Data Exchange (ETDEWEB)

    Fuesser, R.; Weber, O. [Mann and Hummel (Germany)

    1999-07-01

    This paper describes the design and development of the air intake and exhaust system of a fuel cell powered road vehicle. In this instance the automotive supplier designed both the air intake and the exhaust system. The fuel cell engine gives a cold combustion effect making it possible to manufacture the exhaust from plastic materials. (UK)

  16. Modeling Of Proton Exchange Membrane Fuel Cell Systems

    DEFF Research Database (Denmark)

    Nielsen, Mads Pagh

    The objective of this doctoral thesis was to develop reliable steady-state and transient component models suitable to asses-, develop- and optimize proton exchange membrane (PEM) fuel cell systems. Several components in PEM fuel cell systems were characterized and modeled. The developed component...

  17. Neutrophils and macrophages: The main partners of phagocyte cell systems

    Directory of Open Access Journals (Sweden)

    Manuel T. Silva

    2012-07-01

    Full Text Available Biological cellular systems are groups of cells sharing a set of characteristics, mainly key function and origin. Phagocytes are crucial in the host defense against microbial infection. The previously proposed phagocyte cell systems including the most recent and presently prevailing one, the Mononuclear Phagocyte System (MPS, grouped mononuclear cells but excluded neutrophils, creating an unacceptable situation. As neutrophils are archetypical phagocytes that must be members of comprehensive phagocyte systems, M. T. Silva recently proposed the creation of a Myeloid Phagocyte System (MYPS that adds neutrophils to the MPS. The phagocytes grouped in the MYPS include the leukocytes neutrophils, inflammatory monocytes, macrophages and immature myeloid DCs. Here the justifications behind the inclusion of neutrophils in a phagocyte system is expanded and the MYPS are further characterized as a group of dedicated phagocytic cells that function in an interacting and cooperative way in the host defense against microbial infection. Neutrophils and macrophages are considered the main arms of this system.

  18. Miniature Bioreactor System for Long-Term Cell Culture

    Science.gov (United States)

    Gonda, Steve R.; Kleis, Stanley J.; Geffert, Sandara K.

    2010-01-01

    A prototype miniature bioreactor system is designed to serve as a laboratory benchtop cell-culturing system that minimizes the need for relatively expensive equipment and reagents and can be operated under computer control, thereby reducing the time and effort required of human investigators and reducing uncertainty in results. The system includes a bioreactor, a fluid-handling subsystem, a chamber wherein the bioreactor is maintained in a controlled atmosphere at a controlled temperature, and associated control subsystems. The system can be used to culture both anchorage-dependent and suspension cells, which can be either prokaryotic or eukaryotic. Cells can be cultured for extended periods of time in this system, and samples of cells can be extracted and analyzed at specified intervals. By integrating this system with one or more microanalytical instrument(s), one can construct a complete automated analytical system that can be tailored to perform one or more of a large variety of assays.

  19. Two-dimensional diffusion limited system for cell growth

    International Nuclear Information System (INIS)

    A new cell system, the ''sandwich'' system, was developed to supplement multicellular spheroids as tumor analogues. Sandwiches allow new experimental approaches to questions of diffusion, cell cycle effects and radiation resistance in tumors. In this thesis the method for setting up sandwiches is described both theoretically and experimentally followed by its use in x-ray irradiation studies. In the sandwich system, cells are grown in a narrow gap between two glass slides. Where nutrients and waste products can move into or out of the local environment of the cells only by diffusing through the narrow gap between the slides. Due to the competition between cells, self-created gradients of nutrients and metabolic products are set up resulting in a layer of cells which resembles a living spheroid cross section. Unlike the cells of the spheroid, however, cells in all regions of the sandwich are visible. Therefore, the relative sizes of the regions and their time-dependent growth can be monitored visually without fixation or sectioning. The oxygen and nutrient gradients can be ''turned off'' at any time without disrupting the spatial arrangement of the cells by removing the top slide of the assembly and subsequently turned back on if desired. Removal of the top slide also provides access to all the cells, including those near the necrotic center, of the sandwich. The cells can then be removed for analysis outside the sandwich system. 61 refs., 17 figs

  20. Two-dimensional diffusion limited system for cell growth

    Energy Technology Data Exchange (ETDEWEB)

    Hlatky, L.

    1985-11-01

    A new cell system, the ''sandwich'' system, was developed to supplement multicellular spheroids as tumor analogues. Sandwiches allow new experimental approaches to questions of diffusion, cell cycle effects and radiation resistance in tumors. In this thesis the method for setting up sandwiches is described both theoretically and experimentally followed by its use in x-ray irradiation studies. In the sandwich system, cells are grown in a narrow gap between two glass slides. Where nutrients and waste products can move into or out of the local environment of the cells only by diffusing through the narrow gap between the slides. Due to the competition between cells, self-created gradients of nutrients and metabolic products are set up resulting in a layer of cells which resembles a living spheroid cross section. Unlike the cells of the spheroid, however, cells in all regions of the sandwich are visible. Therefore, the relative sizes of the regions and their time-dependent growth can be monitored visually without fixation or sectioning. The oxygen and nutrient gradients can be ''turned off'' at any time without disrupting the spatial arrangement of the cells by removing the top slide of the assembly and subsequently turned back on if desired. Removal of the top slide also provides access to all the cells, including those near the necrotic center, of the sandwich. The cells can then be removed for analysis outside the sandwich system. 61 refs., 17 figs.

  1. A fully automated system for adherent cells microinjection.

    Science.gov (United States)

    Becattini, Gabriele; Mattos, Leonardo S; Caldwell, Darwin G

    2014-01-01

    This paper proposes an automated robotic system to perform cell microinjections to relieve human operators from this highly difficult and tedious manual procedure. The system, which uses commercial equipment currently found on most biomanipulation laboratories, consists of a multitask software framework combining computer vision and robotic control elements. The vision part features an injection pipette tracker and an automatic cell targeting system that is responsible for defining injection points within the contours of adherent cells in culture. The main challenge is the use of bright-field microscopy only, without the need for chemical markers normally employed to highlight the cells. Here, cells are identified and segmented using a threshold-based image processing technique working on defocused images. Fast and precise microinjection pipette positioning over the automatically defined targets is performed by a two-stage robotic system which achieves an average injection rate of 7.6 cells/min with a pipette positioning precision of 0.23 μm. The consistency of these microinjections and the performance of the visual targeting framework were experimentally evaluated using two cell lines (CHO-K1 and HEK) and over 500 cells. In these trials, the cells were automatically targeted and injected with a fluorescent marker, resulting in a correct cell detection rate of 87% and a successful marker delivery rate of 67.5%. These results demonstrate that the new system is capable of better performances than expert operators, highlighting its benefits and potential for large-scale application. PMID:24403406

  2. A fully automated system for adherent cells microinjection.

    Science.gov (United States)

    Becattini, Gabriele; Mattos, Leonardo S; Caldwell, Darwin G

    2014-01-01

    This paper proposes an automated robotic system to perform cell microinjections to relieve human operators from this highly difficult and tedious manual procedure. The system, which uses commercial equipment currently found on most biomanipulation laboratories, consists of a multitask software framework combining computer vision and robotic control elements. The vision part features an injection pipette tracker and an automatic cell targeting system that is responsible for defining injection points within the contours of adherent cells in culture. The main challenge is the use of bright-field microscopy only, without the need for chemical markers normally employed to highlight the cells. Here, cells are identified and segmented using a threshold-based image processing technique working on defocused images. Fast and precise microinjection pipette positioning over the automatically defined targets is performed by a two-stage robotic system which achieves an average injection rate of 7.6 cells/min with a pipette positioning precision of 0.23 μm. The consistency of these microinjections and the performance of the visual targeting framework were experimentally evaluated using two cell lines (CHO-K1 and HEK) and over 500 cells. In these trials, the cells were automatically targeted and injected with a fluorescent marker, resulting in a correct cell detection rate of 87% and a successful marker delivery rate of 67.5%. These results demonstrate that the new system is capable of better performances than expert operators, highlighting its benefits and potential for large-scale application.

  3. Alkaline fuel cells for the regenerative fuel cell energy storage system

    Science.gov (United States)

    Martin, R. E.

    1983-01-01

    The development of the alkaline Regenerative Fuel Cell System, whose fuel cell module would be a derivative of the 12-kW fuel cell power plant currently being produced for the Space Shuttle Orbiter, is reviewed. Long-term endurance testing of full-size fuel cell modules has demonstrated: (1) the extended endurance capability of potassium titanate matrix cells, (2) the long-term performance stability of the anode catalyst, and (3) the suitability of a lightweight graphite structure for use at the anode. These approaches, developed in the NASA-sponsored fuel cell technology advancement program, would also reduce cell weight by nearly one half.

  4. Creating a completely "cell-free" system for protein synthesis.

    Science.gov (United States)

    Smith, Mark Thomas; Bennett, Anthony M; Hunt, Jeremy M; Bundy, Bradley C

    2015-01-01

    Cell-free protein synthesis is a promising tool to take biotechnology outside of the cell. A cell-free approach provides distinct advantages over in vivo systems including open access to the reaction environment and direct control over all chemical components for facile optimization and synthetic biology integration. Promising applications of cell-free systems include portable diagnostics, biotherapeutics expression, rational protein engineering, and biocatalyst production. The highest yielding and most economical cell-free systems use an extract composed of the soluble component of lysed Escherichia coli. Although E. coli lysis can be highly efficient (>99.999%), one persistent challenge is that the extract remains contaminated with up to millions of cells per mL. In this work, we examine the potential of multiple decontamination strategies to further reduce or eliminate bacteria in cell-free systems. Two strategies, sterile filtration and lyophilization, effectively eliminate contaminating cells while maintaining the systems' protein synthesis capabilities. Lyophilization provides the additional benefit of long-term stability at storage above freezing. Technologies for personalized, portable medicine and diagnostics can be expanded based on these foundational sterilized and completely "cell-free" systems.

  5. Peroxisystem: harnessing systems cell biology to study peroxisomes.

    Science.gov (United States)

    Schuldiner, Maya; Zalckvar, Einat

    2015-04-01

    In recent years, high-throughput experimentation with quantitative analysis and modelling of cells, recently dubbed systems cell biology, has been harnessed to study the organisation and dynamics of simple biological systems. Here, we suggest that the peroxisome, a fascinating dynamic organelle, can be used as a good candidate for studying a complete biological system. We discuss several aspects of peroxisomes that can be studied using high-throughput systematic approaches and be integrated into a predictive model. Such approaches can be used in the future to study and understand how a more complex biological system, like a cell and maybe even ultimately a whole organism, works.

  6. A Web-Server of Cell Type Discrimination System

    Directory of Open Access Journals (Sweden)

    Anyou Wang

    2014-01-01

    Full Text Available Discriminating cell types is a daily request for stem cell biologists. However, there is not a user-friendly system available to date for public users to discriminate the common cell types, embryonic stem cells (ESCs, induced pluripotent stem cells (iPSCs, and somatic cells (SCs. Here, we develop WCTDS, a web-server of cell type discrimination system, to discriminate the three cell types and their subtypes like fetal versus adult SCs. WCTDS is developed as a top layer application of our recent publication regarding cell type discriminations, which employs DNA-methylation as biomarkers and machine learning models to discriminate cell types. Implemented by Django, Python, R, and Linux shell programming, run under Linux-Apache web server, and communicated through MySQL, WCTDS provides a friendly framework to efficiently receive the user input and to run mathematical models for analyzing data and then to present results to users. This framework is flexible and easy to be expended for other applications. Therefore, WCTDS works as a user-friendly framework to discriminate cell types and subtypes and it can also be expended to detect other cell types like cancer cells.

  7. A web-server of cell type discrimination system.

    Science.gov (United States)

    Wang, Anyou; Zhong, Yan; Wang, Yanhua; He, Qianchuan

    2014-01-01

    Discriminating cell types is a daily request for stem cell biologists. However, there is not a user-friendly system available to date for public users to discriminate the common cell types, embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs), and somatic cells (SCs). Here, we develop WCTDS, a web-server of cell type discrimination system, to discriminate the three cell types and their subtypes like fetal versus adult SCs. WCTDS is developed as a top layer application of our recent publication regarding cell type discriminations, which employs DNA-methylation as biomarkers and machine learning models to discriminate cell types. Implemented by Django, Python, R, and Linux shell programming, run under Linux-Apache web server, and communicated through MySQL, WCTDS provides a friendly framework to efficiently receive the user input and to run mathematical models for analyzing data and then to present results to users. This framework is flexible and easy to be expended for other applications. Therefore, WCTDS works as a user-friendly framework to discriminate cell types and subtypes and it can also be expended to detect other cell types like cancer cells. PMID:24578634

  8. Towards systems thinking in cell biology education

    OpenAIRE

    Verhoeff, Roald Pieter

    2003-01-01

    Students are taught a large variety of life structures and processes at the cellular level. The concepts used to describe them are mainly drawn from the sub-cellular level, but this knowledge seems to be fragmentary if its integration at the cellular and organismic level remains undone. As a consequence, many students fail to acquire coherent conceptual understanding of the cell as a basic and functional unit of the organism. To enhance the coherence in students’ cell biological knowledge we ...

  9. High Temperature PEM Fuel Cell Systems, Control and Diagnostics

    DEFF Research Database (Denmark)

    Andreasen, Søren Juhl; Kær, Søren Knudsen; Justesen, Kristian Kjær;

    2015-01-01

    Various system topologies are available when it comes to designing high temperature PEM fuel cell systems. Very simple system designs are possible using pure hydrogen, and more complex system designs present themselves when alternative fuels are desired, using reformer systems. The use of reformed...... fuels utilizes one of the main advantages of the high temperature PEM fuel cell: robustness to fuel quality and impurities. In order for such systems to provide efficient, robust, and reliable energy, proper control strategies are needed. The complexity and nonlinearity of many of the components...

  10. Environmental tests of metallization systems for terrestrial photovoltaic cells

    Science.gov (United States)

    Alexander, P., Jr.

    1985-01-01

    Seven different solar cell metallization systems were subjected to temperature cycling tests and humidity tests. Temperature cycling excursions were -50 deg C to 150 deg C per cycle. Humidity conditions were 70 deg C at 98% relative humidity. The seven metallization systems were: Ti/Ag, Ti/Pd/Ag, Ti/Pd/Cu, Ni/Cu, Pd/Ni/Solder, Cr/Pd/Ag, and thick film Ag. All metallization systems showed a slight to moderate decrease in cell efficiencies after subjection to 1000 temperature cycles. Six of the seven metallization systems also evidenced slight increases in cell efficiencies after moderate numbers of cycles, generally less than 100 cycles. The copper based systems showed the largest decrease in cell efficiencies after temperature cycling. All metallization systems showed moderate to large decreases in cell efficiencies after 123 days of humidity exposure. The copper based systems again showed the largest decrease in cell efficiencies after humidity exposure. Graphs of the environmental exposures versus cell efficiencies are presented for each metallization system, as well as environmental exposures versus fill factors or series resistance.

  11. Alkaline regenerative fuel cell systems for energy storage

    Science.gov (United States)

    Schubert, F. H.; Reid, M. A.; Martin, R. E.

    1981-01-01

    A description is presented of the results of a preliminary design study of a regenerative fuel cell energy storage system for application to future low-earth orbit space missions. The high energy density storage system is based on state-of-the-art alkaline electrolyte cell technology and incorporates dedicated fuel cell and electrolysis cell modules. In addition to providing energy storage, the system can provide hydrogen and oxygen for attitude control of the satellite and for life support. During the daylight portion of the orbit the electrolysis module uses power provided by the solar array to generate H2 and O2 from the product water produced by the fuel cell module. The fuel cell module supplies electrical power during the dark period of the orbit.

  12. Investigation of the photovoltaic cell/ thermoelectric element hybrid system performance

    Science.gov (United States)

    Cotfas, D. T.; Cotfas, P. A.; Machidon, O. M.; Ciobanu, D.

    2016-06-01

    The PV/TEG hybrid system, consisting of the photovoltaic cells and thermoelectric element, is presented in the paper. The dependence of the PV/TEG hybrid system parameters on the illumination levels and the temperature is analysed. The maxim power values of the photovoltaic cell, of the thermoelectric element and of the PV/TEG system are calculated and a comparison between them is presented and analysed. An economic analysis is also presented.

  13. Challenges in circulating tumor cell detection by the CellSearch system

    NARCIS (Netherlands)

    Andree, K.C.; Dalum, van G.; Terstappen, L.W.M.M.

    2016-01-01

    Enumeration and characterization of circulating tumor cells (CTC) hold the promise of a real time liquid biopsy. They are however present in a large background of hematopoietic cells making their isolation technically challenging. In 2004, the CellSearch system was introduced as the first and only F

  14. Fostering synergy between cell biology and systems biology.

    Science.gov (United States)

    Eddy, James A; Funk, Cory C; Price, Nathan D

    2015-08-01

    In the shared pursuit of elucidating detailed mechanisms of cell function, systems biology presents a natural complement to ongoing efforts in cell biology. Systems biology aims to characterize biological systems through integrated and quantitative modeling of cellular information. The process of model building and analysis provides value through synthesizing and cataloging information about cells and molecules, predicting mechanisms and identifying generalizable themes, generating hypotheses and guiding experimental design, and highlighting knowledge gaps and refining understanding. In turn, incorporating domain expertise and experimental data is crucial for building towards whole cell models. An iterative cycle of interaction between cell and systems biologists advances the goals of both fields and establishes a framework for mechanistic understanding of the genome-to-phenome relationship.

  15. Flow cell system for miscible displacement experiments

    Energy Technology Data Exchange (ETDEWEB)

    Yoo, S.H.; Kirkham, D.

    1971-02-01

    The use of a continuous graphic recording system for flow-component measurement in miscible displacement experiments is described. This system measures and continuously records radioactive tracer concentrations of effluents of miscible displacement columns. The recordings are needed breakthrough curves. The use of the system obviates fraction collectors.

  16. Cell replacement therapy for central nervous system diseases

    Institute of Scientific and Technical Information of China (English)

    Danju Tso; Randall D. McKinnon

    2015-01-01

    The brain and spinal cord can not replace neurons or supporting glia that are lost through trau-matic injury or disease. In pre-clinical studies, however, neural stem and progenitor cell transplants can promote functional recovery. Thus the central nervous system is repair competent but lacks endogenous stem cell resources. To make transplants clinically feasible, this ifeld needs a source of histocompatible, ethically acceptable and non-tumorgenic cells. One strategy to generate pa-tient-speciifc replacement cells is to reprogram autologous cells such as ifbroblasts into pluripotent stem cells which can then be differentiated into the required cell grafts. However, the utility of pluripotent cell derived grafts is limited since they can retain founder cells with intrinsic neoplastic potential. A recent extension of this technology directly reprograms ifbroblasts into the ifnal graft-able cells without an induced pluripotent stem cell intermediate, avoiding the pluripotent caveat. For both types of reprogramming the conversion efficiency is very low resulting in the need to amplify the cells in culture which can lead to chromosomal instability and neoplasia. Thus to make reprogramming biology clinically feasible, we must improve the efifciency. The ultimate source of replacement cells may reside in directly reprogramming accessible cells within the brain.

  17. Novel Fuel Cells for Coal Based Systems

    Energy Technology Data Exchange (ETDEWEB)

    Thomas Tao

    2011-12-31

    The goal of this project was to acquire experimental data required to assess the feasibility of a Direct Coal power plant based upon an Electrochemical Looping (ECL) of Liquid Tin Anode Solid Oxide Fuel Cell (LTA-SOFC). The objective of Phase 1 was to experimentally characterize the interaction between the tin anode, coal fuel and cell component electrolyte, the fate of coal contaminants in a molten tin reactor (via chemistry) and their impact upon the YSZ electrolyte (via electrochemistry). The results of this work will provided the basis for further study in Phase 2. The objective of Phase 2 was to extend the study of coal impurities impact on fuel cell components other than electrolyte, more specifically to the anode current collector which is made of an electrically conducting ceramic jacket and broad based coal tin reduction. This work provided a basic proof-of-concept feasibility demonstration of the direct coal concept.

  18. An improved reactor system for small-scale fuel processing - the Optiformer concept

    Energy Technology Data Exchange (ETDEWEB)

    Silversand, Fredrik; Karlsson, Charlotte (Catator AB, Lund (Sweden))

    2008-08-15

    Catator AB (CAT) has evaluated a revised design of the previously described Ultraformer concept. In comparison to the original Ultraformer, the new reformer concept (Optiformer) shows enhanced performances with respect to thermo-mechanic durability and conversion efficiencies. The unit is also easy to manufacture and ordinary high-temperature steel alloys may be used. The new concept is based on a helix-shaped tubular heat-exchanger reactor designed by ICI Caldaie (ICI) fitted with CATs proprietary wire-mesh catalyst. The concept has currently been evaluated for production rates between 0.5 and 30 nm3/hr of hydrogen and this report describes a detailed study of a unit for small-scale CHP-applications. Such systems will involve a fuel processor together with a suitable fuel cell, e.g. a solid-oxide fuel cell (SOFC) or a high-temperature PEFC (HT-PEFC). The evaluations performed in this study indicate stable operation over a wide window of capacities with negligible emissions of hydrocarbons. Since it is possible to operate the redesigned unit at a higher temperature (>900 deg C) than the original Ultraformer unit (750- 800 deg C), the conversion degree is much higher for thermo-dynamical reasons. The redesigned unit contains all necessary structures for vaporization, recuperation, effect supply and gas purification in a highly integrated structure. Furthermore, the unit is equipped with an internal insulation and a cooling jacked to reduce the skin temperature of the unit. The reactor has undergone about 100 full thermal cycles without any thermo-mechanical issues or catalyst degradation. Natural gas and different kerosene qualities have so far been evaluated with respect to conversion degree and possible slip of hydrocarbons. The conversion degree at rated load (100%) was above 99%, which enable us to reach superior efficiencies. If the unit were to be used together with a SOFC, the WGS-step could be omitted, reducing the size and weight further from about 2.2 l

  19. A review of fuel cell systems for maritime applications

    Science.gov (United States)

    van Biert, L.; Godjevac, M.; Visser, K.; Aravind, P. V.

    2016-09-01

    Progressing limits on pollutant emissions oblige ship owners to reduce the environmental impact of their operations. Fuel cells may provide a suitable solution, since they are fuel efficient while they emit few hazardous compounds. Various choices can be made with regard to the type of fuel cell system and logistic fuel, and it is unclear which have the best prospects for maritime application. An overview of fuel cell types and fuel processing equipment is presented, and maritime fuel cell application is reviewed with regard to efficiency, gravimetric and volumetric density, dynamic behaviour, environmental impact, safety and economics. It is shown that low temperature fuel cells using liquefied hydrogen provide a compact solution for ships with a refuelling interval up to a tens of hours, but may result in total system sizes up to five times larger than high temperature fuel cells and more energy dense fuels for vessels with longer mission requirements. The expanding infrastructure of liquefied natural gas and development state of natural gas-fuelled fuel cell systems can facilitate the introduction of gaseous fuels and fuel cells on ships. Fuel cell combined cycles, hybridisation with auxiliary electricity storage systems and redundancy improvements are identified as topics for further study.

  20. Visual Servoed Three-Dimensional Cell Rotation System.

    Science.gov (United States)

    Wang, Zenan; Latt, Win Tun; Tan, Steven Yih Min; Ang, Wei Tech

    2015-10-01

    Three-dimensional (3-D) positioning and orientation of embryos/oocytes is necessary to facilitate micromanipulation tasks such as cell injection and cellular structural biopsy commonly performed under a microscope. Conventional cell orientation is performed manually by using a vacuum equipped micropipette to aspirate and release the cell, which is a trial-and-error approach. The conventional method relies heavily on the skill of the operator; it also suffers from low precision, low success rate and low controllability. These drawbacks illustrate the need for a systematic 3-D cell rotational system to automate the cell orientation process. In this paper, we present a noninvasive single cell rotation system that can automatically orientate a zebrafish embryo to a desired position when both the cytoplasm and the yolk are in the focal plane. A three-point-contact model for cell rotation that involves a custom-designed rotational stage is introduced to provide precise rotational position control. A vision recognition algorithm is also proposed to enable the visual servoing function of the system. Experimental results show that the proposed system can achieve high success rates of 92.5% (x-axis rotation with 40 trails) and 97.5% (about the z-axis with 80 trails). The system can also successfully complete 3-D cell orientation at an average speed of 31 s/cell with a high in-plane rotation accuracy of 0.3 (°) . As a high precise, high controllable and deterministic cell manipulating system, it provides a starting point for automated cell manipulation for intracytoplasmic sperm injection and embryo biopsy for preimplantation genetic diagnosis. PMID:25993702

  1. Research on Software-Cell-Based Software System

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The aim of research on software architecture is to improve the quality attributes of software sys tems, such as security, reliability, maintainability, testability , reassembility , evolvability. However, a sin gle running system is hard to achieve all these goals. In this paper, software-cell is introduced as the basic u nit throughout developing process. Then it is further advanced that a robust, safe and high-quality software system is composed of a running system and four supportive systems. This paper especially discusses the structure of software-cell, the construction of the five systems, and the relations between them.

  2. Photovoltaic Test and Demonstration Project. [for solar cell power systems

    Science.gov (United States)

    Forestieri, A. F.; Brandhorst, H. W., Jr.; Deyo, J. N.

    1976-01-01

    The Photovoltaic Test and Demonstration Project was initiated by NASA in June, 1975, to develop economically feasible photovoltaic power systems suitable for a variety of terrestrial applications. Objectives include the determination of operating characteristic and lifetimes of a variety of solar cell systems and components and development of methodology and techniques for accurate measurements of solar cell and array performance and diagnostic measurements for solar power systems. Initial work will be concerned with residential applications, with testing of the first prototype system scheduled for June, 1976. An outdoor 10 kW array for testing solar power systems is under construction.

  3. Study on the Architecture of Control System for Manufacturing Cells

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    The depiction of the agile manufacturing cell includes a synopsis of some of the change proficiencies obtained by the configuration. To achieve agile configuration, the cell control system for agile manufacturing must be rapidly and efficiently generated or modified. In this paper, the object-oriented architecture is defined that supports design and implementation of highly reconfigurable control systems for agile manufacturing cells, which is composed of database objects, control objects, and resource objects, so as to reduce costs and to increase the control system's agility with respect to changing environment.

  4. Process modeling of fuel cell vehicle power system

    Institute of Scientific and Technical Information of China (English)

    CHEN LiMing; LIN ZhaoJia; MA ZiFeng

    2009-01-01

    Constructed here is a mathematic model of PEM Fuel Cell Vehicle Power System which is composed of fuel supply model, fuel cell stack model and water-heat management model. The model was developed by Matiab/Simulink to evaluate how the major operating variables affect the output performances. Itshows that the constructed model can represent characteristics of the power system closely by comparing modeling results with experimental data, and it can be used in the study and design of fuel cell vehicle power system.

  5. Independent Analysis of Real-Time, Measured Performance Data From Microcogenerative Fuel Cell Systems Installed in Buildings

    Energy Technology Data Exchange (ETDEWEB)

    Dillon, Heather E.; Colella, Whitney G.

    2015-06-01

    Pacific Northwest National Laboratory (PNNL) is working with industry to independently monitor up to 15 distinct 5 kW-electric (kWe) combined heat and power (CHP) high temperature (HT) proton exchange membrane (PEM) fuel cell systems (FCSs) installed in light commercial buildings. This research paper discusses an evaluation of the first six months of measured performance data acquired at a 1 s sampling rate from real-time monitoring equipment attached to the FCSs at building sites. Engineering performance parameters are independently evaluated. Based on an analysis of the first few months of measured operating data, FCS performance is consistent with manufacturer-stated performance. Initial data indicate that the FCSs have relatively stable performance and a long-term average production of about 4.57 kWe of power. This value is consistent with, but slightly below, the manufacturer's stated rated electric power output of 5 kWe. The measured system net electric efficiency has averaged 33.7%, based on the higher heating value (HHV) of natural gas fuel. This value, also, is consistent with, but slightly below, the manufacturer's stated rated electric efficiency of 36%. The FCSs provide low-grade hot water to the building at a measured average temperature of about 48.4 degrees C, lower than the manufacturer's stated maximum hot water delivery temperature of 65 degrees C. The uptime of the systems is also evaluated. System availability can be defined as the quotient of total operating time compared to time since commissioning. The average values for system availability vary between 96.1 and 97.3%, depending on the FCS evaluated in the field. Performance at rated value for electrical efficiency (PRVeff) can be defined as the quotient of the system time operating at or above the rated electric efficiency and the time since commissioning. The PRVeff varies between 5.6% and 31.6%, depending on the FCS field unit evaluated. Performance at rated value for

  6. PDMS/glass microfluidic cell culture system for cytotoxicity tests and cells passage

    DEFF Research Database (Denmark)

    Ziolkowska, K.; Jedrych, E.; Kwapiszewski, R.;

    2010-01-01

    In this paper, hybrid (PDMS/glass) microfluidic cell culture system (MCCS) integrated with the concentration gradient generator (CGG) is presented. PDMS gas permeability enabled cells' respiration in the fabricated microdevices and excellent glass hydrophilicity allowed successful cells' seeding....... The human lung carcinoma cells (A549) were cultured in the microdevice for several days. The growth and proliferation of cells was monitored using an inverted fluorescence microscope. After the cells' confluence was achieved in the microchambers, the novel method of cells' passaging in the designed...... microdevice was developed and successfully tested. The MCCS microdevice is fully reusable, i.e. it can be used several times for various cell culture and cytotoxic experiments. The suitability of designed MCCS for cell-based cytotoxicity assay application was verified using 1,4-dioxane as a model toxic agent...

  7. Usability and Applicability of Microfluidic Cell Culture Systems

    DEFF Research Database (Denmark)

    Hemmingsen, Mette

    , these devices still lack general implementation into biological research laboratories. In this project, the usability and applicability of microfluidic cell culture systems have been investigated. The tested systems display good properties regarding optics and compatibility with standard laboratory equipment......Microfluidic cell culture has been a research area with great attention the last decade due to its potential to mimic the in vivo cellular environment more closely compared to what is possible by conventional cell culture methods. Many exciting and complex devices have been presented providing...... possibilities for, for example, precise control of the chemical environment, 3D cultures, controlled co-culture of different cell types or automated, individual control of up to 96 cell culture chambers in one integrated system. Despite the great new opportunities to perform novel experimental designs...

  8. Chip based electroanalytical systems for cell analysis

    DEFF Research Database (Denmark)

    Spegel, C.; Heiskanen, A.; Skjolding, L.H.D.;

    2008-01-01

    This review with 239 references has as its aim to give the reader an introduction to the kinds of methods used for developing microchip based electrode systems as well as to cover the existing literature on electroanalytical systems where microchips play a crucial role for 'nondestructive...

  9. Respiratory systems of the Bacillus cereus mother cell and forespore.

    OpenAIRE

    Escamilla, J E; R. Ramírez; Del-Arenal, P; Aranda, A.

    1986-01-01

    The respiratory systems of the mother cells and forespores of Bacillus cereus were compared throughout the maturation stages (III to VI) of sporulation. The results indicated that both cell compartments contain the same assortment of oxidoreductases and cytochromes. However membrane fractions from young forespores were clearly distinct from those of the mother cell, i.e., lower content of cytochrome aa3, lower cytochrome c oxidase activity, higher concentration of cytochrome o, and a lower se...

  10. Neuronal Chemokines: Versatile Messengers In Central Nervous System Cell Interaction

    OpenAIRE

    de Haas, A. H.; van Weering, H. R. J.; Jong, E.K.; Boddeke, H. W. G. M.; Biber, K.P.H.

    2007-01-01

    Whereas chemokines are well known for their ability to induce cell migration, only recently it became evident that chemokines also control a variety of other cell functions and are versatile messengers in the interaction between a diversity of cell types. In the central nervous system (CNS), chemokines are generally found under both physiological and pathological conditions. Whereas many reports describe chemokine expression in astrocytes and microglia and their role in the migration of leuko...

  11. Baculovirus integration with the vertebrate cells in system in vitro

    Directory of Open Access Journals (Sweden)

    Strokovskaya L. I.

    2010-11-01

    Full Text Available In this review the literature data are analyzed relative to the study of a new vector system for the cells of vertebrates, based on the insect viruses – baculoviruses. The ways and mechanisms of recombinant baculoviruses penetration into cells, the factors, which influence the effectiveness of transduction, the principles of the modification of virus display, and the reaction of the different types of cells on virus introduction are examined. The prospects of using recombinant baculoviruses in cellular engineering are discussed.

  12. Power Conversion System Strategies for Fuel Cell Vehicles

    Institute of Scientific and Technical Information of China (English)

    Kaushik Rajashekara

    2005-01-01

    Power electronics is an enabling technology for the development of environmental friendly fuel cell vehicles, and to implement the various vehicle electrical architectures to obtain the best performance. In this paper, power conversion strategies for propulsion and auxiliary power unit applications are described. The power electronics strategies for the successful development of the fuel cell vehicles are presented. The fuel cell systems for propulsion and for auxiliary power unit applications are also discussed.

  13. Monocrystalline silicon solar cells applied in photovoltaic system

    OpenAIRE

    L.A. Dobrzański; A. Drygała; M. Giedroć; Macek, M

    2012-01-01

    Purpose: The aim of the paper is to fabricate the monocrystalline silicon solar cells using the conventional technology by means of screen printing process and to make of them photovoltaic system.Design/methodology/approach: The investigation of current – voltage characteristic to determinate basic electrical properties of monocrystalline silicon solar cells were investigated under Standard Test Condition. Photovoltaic module was produced from solar cells with the largest short-circuit curren...

  14. Cell-based microfluidic platform for mimicking human olfactory system.

    Science.gov (United States)

    Lee, Seung Hwan; Oh, Eun Hae; Park, Tai Hyun

    2015-12-15

    Various attempts have been made to mimic the human olfactory system using human olfactory receptors (hORs). In particular, OR-expressed cell-based odorant detection systems mimic the smell sensing mechanism of humans, as they exploit endogenous cellular signaling pathways. However, the majority of such cell-based studies have been performed in the liquid phase to maintain cell viability, and liquid odorants were used as detection targets. Here, we present a microfluidic device for the detection of gaseous odorants which more closely mimics the human olfactory system. Cells expressing hOR were cultured on a porous membrane. The membrane was then flipped over and placed between two compartments. The upper compartment is the gaseous part where gaseous odorants are supplied, while the lower compartment is the aqueous part where viable cells are maintained in the liquid medium. Using this simple microfluidic device, we were able to detect gaseous odorant molecules by a fluorescence signal. The fluorescence signal was generated by calcium influx resulting from the interaction between odorant molecules and the hOR. The system allowed detection of gaseous odorant molecules in real-time, and the findings showed that the fluorescence responses increased dose-dependently in the range of 0-2 ppm odorant. In addition, the system can discriminate among gaseous odorant molecules. This microfluidic system closely mimics the human olfactory system in the sense that the submerged cells detect gaseous odorants.

  15. Nanobiocatalysts for biofuel cells and biosensor systems

    Directory of Open Access Journals (Sweden)

    Radivoje M. Prodanović

    2011-10-01

    Full Text Available This overview summarizes the application of enzymes in the manufacture and design of biofuel cells and biosensors. The emphasis will be put on the protein engineering techniques used for improving the properties of enzymes such as nanobiocatalysts, e.g. immobilization orientation, stability, activity and efficiency of electron transfer between immobilized enzymes and electrodes. Some possible applications in the military and some future designs of these electric devices will be discussed as well.

  16. Method of operating a direct dme fuel cell system

    DEFF Research Database (Denmark)

    2011-01-01

    The present invention relates to a method of operating a fuel cell system comprising one or more fuel cells with a proton exchange membrane, wherein the membrane is composed of a polymeric material comprising acid-doped polybenzimidazole (PBI). The method comprises adjusting the operating...

  17. T-cell-directed therapies in systemic lupus erythematosus.

    Science.gov (United States)

    Nandkumar, P; Furie, R

    2016-09-01

    Drug development for the treatment of systemic lupus erythematosus (SLE) has largely focused on B-cell therapies. A greater understanding of the immunopathogenesis of SLE coupled with advanced bioengineering has allowed for clinical trials centered on other targets for SLE therapy. The authors discuss the benefits and shortcomings of focusing on T-cell-directed therapies in SLE and lupus nephritis clinical trials.

  18. GATE Center for Automotive Fuel Cell Systems at Virginia Tech

    Energy Technology Data Exchange (ETDEWEB)

    Nelson, Douglas [Virginia Polytechnic Inst. and State Univ. (Virginia Tech), Blacksburg, VA (United States)

    2011-09-30

    The Virginia Tech GATE Center for Automotive Fuel Cell Systems (CAFCS) achieved the following objectives in support of the domestic automotive industry: Expanded and updated fuel cell and vehicle technologies education programs; Conducted industry directed research in three thrust areas development and characterization of materials for PEM fuel cells; performance and durability modeling for PEM fuel cells; and fuel cell systems design and optimization, including hybrid and plug-in hybrid fuel cell vehicles; Developed MS and Ph.D. engineers and scientists who are pursuing careers related to fuel cells and automotive applications; Published research results that provide industry with new knowledge which contributes to the advancement of fuel cell and vehicle systems commercialization. With support from the Dept. of Energy, the CAFCS upgraded existing graduate course offerings; introduced a hands-on laboratory component that make use of Virginia Tech's comprehensive laboratory facilities, funded 15 GATE Fellowships over a five year period; and expanded our program of industry interaction to improve student awareness of challenges and opportunities in the automotive industry. GATE Center graduate students have a state-of-the-art research experience preparing them for a career to contribute to the advancement fuel cell and vehicle technologies.

  19. The ubiquitin-proteasome system in glioma cell cycle control

    Directory of Open Access Journals (Sweden)

    Vlachostergios Panagiotis J

    2012-07-01

    Full Text Available Abstract A major determinant of cell fate is regulation of cell cycle. Tight regulation of this process is lost during the course of development and progression of various tumors. The ubiquitin-proteasome system (UPS constitutes a universal protein degradation pathway, essential for the consistent recycling of a plethora of proteins with distinct structural and functional roles within the cell, including cell cycle regulation. High grade tumors, such as glioblastomas have an inherent potential of escaping cell cycle control mechanisms and are often refractory to conventional treatment. Here, we review the association of UPS with several UPS-targeted proteins and pathways involved in regulation of the cell cycle in malignant gliomas, and discuss the potential role of UPS inhibitors in reinstitution of cell cycle control.

  20. High Efficiency Direct Methane Solid Oxide Fuel Cell System Project

    Data.gov (United States)

    National Aeronautics and Space Administration — NASA has a defined need for energy dense and highly efficient energy storage and power delivery systems for future space missions. Compared to other fuel cell...

  1. Integrating fuel cell power systems into building physical plants

    Energy Technology Data Exchange (ETDEWEB)

    Carson, J. [KCI Technologies, Inc., Hunt Valley, MD (United States)

    1996-12-31

    This paper discusses the integration of fuel cell power plants and absorption chillers to cogenerate chilled water or hot water/steam for all weather air conditioning as one possible approach to building system applications. Absorption chillers utilize thermal energy in an absorption based cycle to chill water. It is feasible to use waste heat from fuel cells to provide hydronic heating and cooling. Performance regimes will vary as a function of the supply and quality of waste heat. Respective performance characteristics of fuel cells, absorption chillers and air conditioning systems will define relationships between thermal and electrical load capacities for the combined systems. Specifically, this paper develops thermodynamic relationships between bulk electrical power and cooling/heating capacities for combined fuel cell and absorption chiller system in building applications.

  2. Contribution to a Danish action plan for development and demonstration of CHP from solid biomass; Oplaeg til en national handlingsplan for udvikling og demonstration indenfor kraftvarme fra fast biomasse

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, Morten Tony

    2011-01-15

    The report is the contribution from the industry to an action plan for development and demonstration of CHP technology for solid biomass. The report aims to serve as inspiration and basis for administrators and applicants of Danish funding schemes for development and demonstration in future tenders. Although Danish-based cogeneration technologies for solid biofuels are advanced compared to the competitors in many areas there is a large need to continuously improve the technology by sustained development and demonstration activities. The aim is to overcome the technological barriers that this project has identified and thus maintain competitiveness. The industry currently has very strong focus on market deployment of especially technologies for cogeneration in small scale (up to 15 MW thermal power) and on the overall economy of these plants. Reference installations that displays many operational hours with a reasonable economy, are crucial for investors. Currently, no companies market commercial plants that have sufficiently low costs to operate under Danish conditions and few do for the conditions found internationally. Thus, from the industry perspective there is still a need for development and demonstration of CHP technology below 15 MW thermal. The analysis does not exclude any technology tracks, but the development and demonstration efforts should lead to improvements in conditions such as availability, efficiencies and operating and maintenance costs. Also technologies for large plants and systems need to be improved with respect to availability and efficiency and reduced operating and maintenance costs. For all technologies, there is a need to develop the use of special solid biofuels that on the one hand may have troublesome characteristics but on the other may help lower operating costs. The Danish-based companies have good opportunities to find support for the development and demonstration effort. A number of support programs and pools are in place and

  3. Phase Space Cell in Nonextensive Classical Systems

    OpenAIRE

    Piero Quarati; Francesco Quarati

    2003-01-01

    We calculate the phase space volume $\\Omega$ occupied by a nonextensive system of $N$ classical particles described by an equilibrium (or steady-state, or long-term stationary state of a nonequilibrium system) distribution function, which slightly deviates from Maxwell-Boltzmann (MB) distribution in the high energy tail. We explicitly require that the number of accessible microstates does not change respect to the extensive MB case. We also derive, within a classical scheme, an analytical exp...

  4. Porcine skin flow-through diffusion cell system.

    Science.gov (United States)

    Baynes, R E

    2001-11-01

    Porcine Skin Flow-Through Diffusion Cell System (Ronald E. Baynes, North Carolina State University, Raleigh, North Carolina). Porcine skin can be used in a diffusion cell apparatus to study the rate and extent of absorption of topically applied chemicals through the skin. Although the skin of a number of animals can be used in this system, that of the pig most closely approximates human skin anatomically and physiologically.

  5. PV-Wind System with Fuel Cell & Electrolyzer

    Directory of Open Access Journals (Sweden)

    Deepa Sharma

    2015-12-01

    Full Text Available In this paper, a detailed modeling and simulation of solar cell/ wind turbine/ fuel cell hybrid power system is developed using a novel topology to complement each other and to alleviate the effects of environmental variations. Comparing with the other sources , the renewable energy is inexhaustible and has non-pollution characteristics. The solar energy, wind power, hydraulic power and tidal energy are natural resources of the interest to generate electrical power. As the wind turbine output power varies with the wind speed and the solar cell output power varies with both the ambient temperature and radiation, a fuel cell with ultra capacitor bank can be integrated to ensure that the system performs under all conditions. Excess wind and solar energies when available are converted to hydrogen using electrolysis for later use in the fuel cell. In this paper dynamic modeling of various components of this isolated system system is presented. Transient responses of the system to step change in the load, ambient temperature, radiation, and wind speed in a number of possible situations are studied. Modeling and simulations are conducted using MATLAB/Simulink software packages to verify the effectiveness of the proposed system. The results show that the proposed hybrid power system can tolerate the rapid change in natural conditions and suppress the effects of these fluctuations on the voltage within the acceptable range.The proposed system can be used for off grid power generation in non interconnected areas or remote isolated communities of nation.

  6. Laser Micro-beam Manipulation System for Cells

    Institute of Scientific and Technical Information of China (English)

    孟祥旺; 李岩; 张书练; 张志诚; 赵南明

    2002-01-01

    This paper introduces a laser micro-beam system for cells manipulation. The laser micro-beam system comprises a laser scissors and a laser tweezers, which are focused by a Nd∶YAG laser and a He-Ne laser through a microscope objective, respectively. Not only the overall design of the laser micro-beam system is discussed, but also the design and choice of the critical components. A laser micro-beam system was constructed and anticipated experiment results were gained. Yeast cells can be successfully manipulated with the laser tweezers. Chromosomes can be successfully incised with the laser scissors.

  7. Fuel cells for stationary energy supply; Brennstoffzellen in der stationaeren Energieversorgung

    Energy Technology Data Exchange (ETDEWEB)

    Leprich, Uwe; Thiele, Andreas [Institut fuer ZukunftsEnergieSysteme (IZES), Saarbruecken (Germany)

    2005-06-15

    Starting point for this investigation was the question, whether the incentives, caused by the CHP law from March the 19th 2002, are short- and medium term adequate to introduce fuel cells as small CHP plants broadly on the market or rather develop them at least to a standard of market maturity. This has - based on our analysis - definitely to be answered in the negative: for this, the fixed bonus is too small to influence the costs for investment and running of a fuel cell plant lasting. One of the aims of the CHP law - the reduction of the yearly CO2-emissions in Germany by a broader introduction of the technology on the market - can actually not be reached. Although, fuel cells may obtain a quite important climate-political significance, if their economical availability will be secured and related basic conditions are set today. By the CHP law, the federal government however demonstrated publicly that it is willing to support the development of the fuel cell and its introduction on the market. This signal is not only supporting the industry to align its middle- and long term decisions but it is also helping users and operators of fuel cells by providing a legal security about the guarantee for grid connection and remuneration Based on the perspectives for an establishing of small CHP plants including fuel cells, the range of possible stimulating and supporting measures was investigated in a second step. While doing so, it was differentiated between a flanking of the existing CHP law, its further development and other alternative measures. By this, there are several starting points to realize changes or rather adaptations in the CHP law. According to this investigation and in the interest of an increased spreading of small CHP- and fuel cell plants, these possibilities should be made use of as fast as possible. The investigation was terminated by examinating selected technical, energy-economical as well as energy political chances and requirements for hydrogen

  8. Stem cell therapy for central nerve system injuries:glial cells hold the key

    Institute of Scientific and Technical Information of China (English)

    Li Xiao; Chikako Saiki; Ryoji Ide

    2014-01-01

    Mammalian adult central nerve system (CNS) injuries are devastating because of the intrinsic dififculties for effective neuronal regeneration. The greatest problem to be overcome for CNS recovery is the poor regeneration of neurons and myelin-forming cells, oligodendrocytes. En-dogenous neural progenitors and transplanted exogenous neuronal stem cells can be the source for neuronal regeneration. However, because of the harsh local microenvironment, they usually have very low efifcacy for functional neural regeneration which cannot compensate for the loss of neurons and oligodendrocytes. Glial cells (including astrocytes, microglia, oligodendrocytes and NG2 glia) are the majority of cells in CNS that provide support and protection for neurons. Inside the local microenvironment, glial cells largely inlfuence local and transplanted neural stem cells survival and fates. This review critically analyzes current ifnding of the roles of glial cells in CNS regeneration, and highlights strategies for regulating glial cells’ behavior to create a permis-sive microenvironment for neuronal stem cells.

  9. Modeling, analysis and control of fuel cell hybrid power systems

    Science.gov (United States)

    Suh, Kyung Won

    Transient performance is a key characteristic of fuel cells, that is sometimes more critical than efficiency, due to the importance of accepting unpredictable electric loads. To fulfill the transient requirement in vehicle propulsion and portable fuel cell applications, a fuel cell stack is typically coupled with a battery through a DC/DC converter to form a hybrid power system. Although many power management strategies already exist, they all rely on low level controllers that realize the power split. In this dissertation we design controllers that realize various power split strategies by directly manipulating physical actuators (low level commands). We maintain the causality of the electric dynamics (voltage and current) and investigate how the electric architecture affects the hybridization level and the power management. We first establish the performance limitations associated with a stand-alone and power-autonomous fuel cell system that is not supplemented by an additional energy storage and powers all its auxiliary components by itself. Specifically, we examine the transient performance in fuel cell power delivery as it is limited by the air supplied by a compressor driven by the fuel cell itself. The performance limitations arise from the intrinsic coupling in the fluid and electrical domain between the compressor and the fuel cell stack. Feedforward and feedback control strategies are used to demonstrate these limitations analytically and with simulations. Experimental tests on a small commercial fuel cell auxiliary power unit (APU) confirm the dynamics and the identified limitations. The dynamics associated with the integration of a fuel cell system and a DC/DC converter is then investigated. Decentralized and fully centralized (using linear quadratic techniques) controllers are designed to regulate the power system voltage and to prevent fuel cell oxygen starvation. Regulating these two performance variables is a difficult task and requires a compromise

  10. Evaluation of ISABELLE full cell ultra high vacuum system

    International Nuclear Information System (INIS)

    The ISABELLE Full Cell Vacuum System consisting of a 40 m long, by 8.8 cm diameter stainless steel tube pumped by seven pumping stations was assembled and processed for 10-12 Torr operation. Evaluation and testing of the system and its sub-assemblies has been completed. Detail design of system components and the determination of the conditioning process was completed. The best procedure to rough pump, leak test, vacuum bake the system, condition pumps, degas gauges, turn on ion pumps and flash sublimation pumps was established. Pressures below 2 x 10-11 Torr are now routinely achieved in normal operation of the Full Cell. This includes pump down after replacement of various components and pump down after back fill with moist unfiltered air. The techniques developed for the Full Cell will be used to build the ISABELLE Ultra High Vacuum System

  11. Global behavior of gear system using mixed cell mapping

    Institute of Scientific and Technical Information of China (English)

    SHEN; Yunwen; LIU; Mengjun; DONG; Haijun

    2004-01-01

    In some mechanical nonlinear systems, the transient motion will be undergoing a very long process and the attractor-basin boundaries are so complicated that some difficulties occur in analyzing the system global behavior. To solve this problem a mixed cell mapping method based on the point mapping and the principle of simple cell mapping is developed. The algorithm of the mixed cell mapping is studied. A dynamic model of a gear pair is established with the backlash, damping, transmission error and the time-varying stiffness taken into consideration. The global behaviors of this system are analyzed. The coexistence of the system attractors and the respective attractor-basin of each attractor with different parameters are obtained, thus laying a theoretical basis for improvement of the dynamic behaviors of gear system.

  12. Integrated energy markets and varying degrees of liberalisation: price links, bundled sales and CHP production exemplified by Northern European experiences

    International Nuclear Information System (INIS)

    Liberalisation of energy markets has during the last 20 years been gradually introduced in many countries. The liberalisation has led to concerns regarding the markets' state of competition and fears that market power existence can result in less efficiency gains than what is expected from liberalisation. Concerns have also been raised as to whether specific consumer groups will be affected by limited competition in markets. Much of the concern has been concentrated on the electricity markets, but the development of energy sectors with integration of activities within natural gas, electricity and the oil sector creates the need to examine market power aspects across these markets. This paper examines the concentration trends in the Northern European markets for electricity and natural gas, combined with regional district heating aspects, especially with respect to the situation in Denmark. The situation with natural gas companies supplying to both small-scale CHP and to retail heat customers is discussed, for instance, which changes of regulatory regime for domestic heating customers should be considered when the natural gas market is being liberalised? The interlinked nature of the energy markets is described and examples of impacts from one market with limited competition to other markets with seemingly well-functioning competition are given. The specific case of large CHP production facilities with output on the regulated district heating market and the competitive Nordic electricity market is examined. How much of the fluctuations in price experienced in electricity markets should be reflected in the price of heating supplies? To which degree do the heating customers have to bear the burden of low-electricity market prices? Regulation of liberalised markets is discussed focusing on the interaction between one regulated market and the related energy markets that are liberalised. Existing regulation on the markets are compared to a situation where liberalisation

  13. Optimization of Buffalo (Bubalus bubalis Embryonic Stem Cell Culture System

    Directory of Open Access Journals (Sweden)

    Mohammad Zandi

    2015-07-01

    Full Text Available Objective: In order to retain an undifferentiated pluripotent state, embryonic stem (ES cells have to be cultured on feeder cell layers. However, use of feeder layers limits stem cell research, since experimental data may result from a combined ES cell and feeder cell response to various stimuli. Materials and Methods: In this experimental study, a buffalo ES cell line was established from in vitro derived blastocysts and characterized by the Alkaline phosphatase (AP and immunoflourescence staining of various pluripotency markers. We examined the effect of various factors like fibroblast growth factor 2 (FGF-2, leukemia inhibitory factor (LIF and Y-27632 to support the growth and maintenance of bubaline ES cells on gelatin coated dishes, in order to establish feeder free culture systems. We also analyzed the effect of feeder-conditioned media on stem cell growth in gelatin based cultures both in the presence as well as in the absence of the growth factors. Results: The results showed that Y-27632, in the presence of FGF-2 and LIF, resulted in higher colony growth and increased expression of Nanog gene. Feeder-Conditioned Medium resulted in a significant increase in growth of buffalo ES cells on gelatin coated plates, however, feeder layer based cultures produced better results than gelatin based cultures. Feeder layers from buffalo fetal fibroblast cells can support buffalo ES cells for more than two years. Conclusion: We developed a feeder free culture system that can maintain buffalo ES cells in the short term, as well as feeder layer based culture that can support the long term maintenance of buffalo ES cells.

  14. Synthetic biology outside the cell: linking computational tools to cell-free systems.

    Science.gov (United States)

    Lewis, Daniel D; Villarreal, Fernando D; Wu, Fan; Tan, Cheemeng

    2014-01-01

    As mathematical models become more commonly integrated into the study of biology, a common language for describing biological processes is manifesting. Many tools have emerged for the simulation of in vivo synthetic biological systems, with only a few examples of prominent work done on predicting the dynamics of cell-free synthetic systems. At the same time, experimental biologists have begun to study dynamics of in vitro systems encapsulated by amphiphilic molecules, opening the door for the development of a new generation of biomimetic systems. In this review, we explore both in vivo and in vitro models of biochemical networks with a special focus on tools that could be applied to the construction of cell-free expression systems. We believe that quantitative studies of complex cellular mechanisms and pathways in synthetic systems can yield important insights into what makes cells different from conventional chemical systems. PMID:25538941

  15. Synthetic Biology Outside the Cell: Linking Computational Tools to Cell-Free Systems

    Directory of Open Access Journals (Sweden)

    Daniel eLewis

    2014-12-01

    Full Text Available As mathematical models become more commonly integrated into the study of biology, a common language for describing biological processes is manifesting. Many tools have emerged for the simulation of in vivo systems, with only a few examples of prominent work done on predicting the dynamics of cell-free systems. At the same time, experimental biologists have begun to study dynamics of in vitro systems encapsulated by amphiphilic molecules, opening the door for the development of a new generation of biomimetic systems. In this review, we explore both in vivo and in vitro models of biochemical networks with a special focus on tools that could be applied to the construction of cell-free expression systems. We believe that quantitative studies of complex cellular mechanisms and pathways in synthetic systems can yield important insights into what makes cells different from conventional chemical systems.

  16. Synthetic biology outside the cell: linking computational tools to cell-free systems.

    Science.gov (United States)

    Lewis, Daniel D; Villarreal, Fernando D; Wu, Fan; Tan, Cheemeng

    2014-01-01

    As mathematical models become more commonly integrated into the study of biology, a common language for describing biological processes is manifesting. Many tools have emerged for the simulation of in vivo synthetic biological systems, with only a few examples of prominent work done on predicting the dynamics of cell-free synthetic systems. At the same time, experimental biologists have begun to study dynamics of in vitro systems encapsulated by amphiphilic molecules, opening the door for the development of a new generation of biomimetic systems. In this review, we explore both in vivo and in vitro models of biochemical networks with a special focus on tools that could be applied to the construction of cell-free expression systems. We believe that quantitative studies of complex cellular mechanisms and pathways in synthetic systems can yield important insights into what makes cells different from conventional chemical systems.

  17. A Cell-in-the-Loop Approach to Systems Modelling and Simulation of Energy Storage Systems

    Directory of Open Access Journals (Sweden)

    James Marco

    2015-08-01

    Full Text Available This research is aligned with the engineering challenge of scaling-up individual battery cells into a complete energy storage system (ESS. Manufacturing tolerances, coupled with thermal gradients and the differential electrical loading of adjacent cells, can result in significant variations in the rate of cell degradation, energy distribution and ESS performance. The uncertain transition from cell to system often manifests itself in over-engineered, non-optimal ESS designs within both the transport and energy sectors. To alleviate these issues, the authors propose a novel model-based framework for cell-in-the-loop simulation (CILS in which a physical cell may be integrated within a complete model of an ESS and exercised against realistic electrical and thermal loads in real-time. This paper focuses on the electrical integration of both real and simulated cells within the CILS test environment. Validation of the CILS approach using real-world electric vehicle data is presented for an 18650 cell. The cell is integrated within a real-time simulation model of a series string of similar cells in a 4sp1 configuration. Results are presented that highlight the impact of cell variability (i.e., capacity and impedance on the energy available from the multi-cell system and the useable capacity of the physical cell.

  18. Solar regenerative fuel cell system for high altitude airships

    International Nuclear Information System (INIS)

    'Full text': A closed-loop regenerative fuel cell (RFC) system that serves as an energy storage device for space activities is studied through dynamic simulations. The unique nature of the closed-loop RFC makes it an ideal power system for key applications in homeland defense and earth observatory systems such as high altitude aircrafts /airships, unmanned aerial vehicles, and in planetary exploration for flyer or for surface power. The RFC considered using the photovoltaic cells to produce electric power during the day, part of which is used to produce hydrogen and oxygen through electrolysis. The stored hydrogen and oxygen is used through a fuel cell to produce electric power during night hours. A MATLAB/SIMULINK model was developed for the components of the RFC that include a fuel cell, electrolyzer, photovoltaic solar array, power bus, humidifiers, compressor/motor assembly, expander, pumps, phase separators, storage tanks for hydrogen, oxygen and water, control valves and piping, electric grid system and controls. A proton exchange membrane (PEM) fuel cell and PEM electrolyzer were modeled in detail that included the mass momentum, energy, chemical reaction rates at cathode and anode. The PEM fuel cell voltage was modeled accounting cell activation and ohmic polarizations. A modular approach was used to develop models for each component. Component models were based on fundamental physics to the extent practical. Steady state and dynamic response of the RFC for different operational conditions including start-up, shut down, load changes and (accidental) transients was studied. (author)

  19. Clinical Application of Stem Cells in the Cardiovascular System

    Science.gov (United States)

    Stamm, Christof; Klose, Kristin; Choi, Yeong-Hoon

    Regenerative medicine encompasses "tissue engineering" - the in vitro fabrication of tissues and/or organs using scaffold material and viable cells - and "cell therapy" - the transplantation or manipulation of cells in diseased tissue in vivo. In the cardiovascular system, tissue engineering strategies are being pursued for the development of viable replacement blood vessels, heart valves, patch material, cardiac pacemakers and contractile myocardium. Anecdotal clinical applications of such vessels, valves and patches have been described, but information on systematic studies of the performance of such implants is not available, yet. Cell therapy for cardiovascular regeneration, however, has been performed in large series of patients, and numerous clinical studies have produced sometimes conflicting results. The purpose of this chapter is to summarize the clinical experience with cell therapy for diseases of the cardiovascular system, and to analyse possible factors that may influence its outcome.

  20. Bringing fuel cells to reality and reality to fuel cells: A systems perspective on the use of fuel cells

    Energy Technology Data Exchange (ETDEWEB)

    Saxe, Maria

    2008-10-15

    The hopes and expectations on fuel cells are high and sometimes unrealistically positive. However, as an emerging technology, much remains to be proven and the proper use of the technology in terms of suitable applications, integration with society and extent of use is still under debate. This thesis is a contribution to the debate, presenting results from two fuel cell demonstration projects, looking into the introduction of fuel cells on the market, discussing the prospects and concerns for the near-term future and commenting on the potential use in a future sustainable energy system. Bringing fuel cells to reality implies finding near-term niche applications and markets where fuel cell systems may be competitive. In a sense fuel cells are already a reality as they have been demonstrated in various applications world-wide. However, in many of the envisioned applications fuel cells are far from being competitive and sometimes also the environmental benefit of using fuel cells in a given application may be questioned. Bringing reality to fuel cells implies emphasising the need for realistic expectations and pointing out that the first markets have to be based on the currently available technology and not the visions of what fuel cells could be in the future. The results from the demonstration projects show that further development and research on especially the durability for fuel cell systems is crucial and a general recommendation is to design the systems for high reliability and durability rather than striving towards higher energy efficiencies. When sufficient reliability and durability are achieved, fuel cell systems may be introduced in niche markets where the added values presented by the technology compensate for the initial high cost

  1. A portable power system using PEM fuel cells

    Energy Technology Data Exchange (ETDEWEB)

    Long, E. [Ball Aerospace and Technologies Corp., Boulder, CO (United States)

    1997-12-31

    Ball has developed a proof-of-concept, small, lightweight, portable power system. The power system uses a proton exchange membrane (PEM) fuel cell stack, stored hydrogen, and atmospheric oxygen as the oxidant to generate electrical power. Electronics monitor the system performance to control cooling air and oxidant flow, and automatically do corrective measures to maintain performance. With the controller monitoring the system health, the system can operate in an ambient environment from 0 C to +50 C. The paper describes system testing, including load testing, thermal and humidity testing, vibration and shock testing, field testing, destructive testing of high-pressure gas tanks, and test results on the fuel cell power system, metal hydride hydrogen storage, high-pressure hydrogen gas storage, and chemical hydride hydrogen storage.

  2. PEM fuel cell systems performance optimisation using the mathematical modeling

    International Nuclear Information System (INIS)

    PEM fuel cell systems and technologies have emerged as viable energy conversion devices for terrestrial applications (stationary and mobile). They offer huge economical and environmental potentials in the next generation power systems, but they are still more expensive than most conventional power conversion devices. Therefore, there is a need to optimize these technologies from the performance and costs point of view. Mathematical modeling proved to be the most important tool for PEM fuel cell optimization, providing the best solution for design, operating condition, experimentation and exploitation. This paper proposes a study for fluid flow channels optimization in order to improve the performance of PEM fuel cell systems. Thus, we run simulations using 3 types of geometries for the flowing channels: serpentine, parallel and spiral channel in order to find the optimum flowing geometry. Concluding, we can consider the modeling like an important alternative for fuel cell optimization and for exploitation/experimentation costs reduction. (authors)

  3. An electrochemical surface plasmon resonance imaging system targeting cell analysis

    Science.gov (United States)

    Zhang, L. L.; Chen, X.; Wei, H. T.; Li, H.; Sun, J. H.; Cai, H. Y.; Chen, J. L.; Cui, D. F.

    2013-08-01

    This paper presents an electrochemical-surface plasmon resonance imaging (EC-SPRI) system, enabling the characterization of optical and electrical properties of cells, simultaneously. The developed surface plasmon resonance (SPR) imaging system was capable of imaging micro cavities with a dimension of 10 μm × 10 μm and differentiated glycerol solutions with a group of refractive indices (RIs). Furthermore, the EC-SPRI system was used to image A549 cells, suggesting corresponding RI and morphology changes during the cell death process. In the end, electrochemical and SPR methods were used in combination, recording oxidation peaks of A549 cells in the cyclic voltage curves and SPR response unit increase, simultaneously.

  4. Flexible 75 kWel Stirling CHP-plant for bio-fuels with low emissions and a high fuel utilization. Final technical report

    Energy Technology Data Exchange (ETDEWEB)

    2011-07-01

    The objective of the project ''Flexible 75 kWel Stirling CHP-plant for bio-fuels with low emissions and a high fuel utilization'' was to combine the Danish experiences with the Stirling engine and updraft gasification with the application of the FLOX gas burner technology for developing and demonstrating a flexible biomass-based small scale CHP plant with 75 kW electrical output, high power efficiency and low emissions. Further, the project has aimed at increasing the technology's reliability and decreasing the need for service. Also, the project has included the development of a control and communication system for unmanned start-up and operation of the plant. During the project the objective was altered and so the development of a new Stirling engine design was done on the 4-cylindred 35 kWe Stirling engine instead of the 8-cylindred 75 kWe Stirling engine. Focus has been on designing a more durable engine designed for easy and fast service. Cold test of the engine has been successful and now full-scale hot tests are to be performed. In the project Stirling DK has also in cooperation with project partner Danish gas Technology Centre developed the Stirling Engine with Diluted Oxidation (SEDIOX) concept which is a combustion technology based on the diluted oxidation principle. A trademark is obtained and also a patent application is filed and pending regarding the SEDIOX combustion chamber concept. All components for the Stirling gasification plant were produced and installed at Svanholm Estate. The plant consisted of one conventional combustion chamber and one SD3E-type Stirling engine. The plant was commissioned in June 2009 and 1,472 hours of operation and 43 MWh of electricity production was achieved before the plant was de-commissioned in February 2010 due to divergences between Svanholm Estate and Stirling DK. During operation the control system including remote access was tested thoroughly and with great success. The new overall

  5. Fuel quality issues in stationary fuel cell systems.

    Energy Technology Data Exchange (ETDEWEB)

    Papadias, D.; Ahmed, S.; Kumar, R. (Chemical Sciences and Engineering Division)

    2012-02-07

    Fuel cell systems are being deployed in stationary applications for the generation of electricity, heat, and hydrogen. These systems use a variety of fuel cell types, ranging from the low temperature polymer electrolyte fuel cell (PEFC) to the high temperature solid oxide fuel cell (SOFC). Depending on the application and location, these systems are being designed to operate on reformate or syngas produced from various fuels that include natural gas, biogas, coal gas, etc. All of these fuels contain species that can potentially damage the fuel cell anode or other unit operations and processes that precede the fuel cell stack. These detrimental effects include loss in performance or durability, and attenuating these effects requires additional components to reduce the impurity concentrations to tolerable levels, if not eliminate the impurity entirely. These impurity management components increase the complexity of the fuel cell system, and they add to the system's capital and operating costs (such as regeneration, replacement and disposal of spent material and maintenance). This project reviewed the public domain information available on the impurities encountered in stationary fuel cell systems, and the effects of the impurities on the fuel cells. A database has been set up that classifies the impurities, especially in renewable fuels, such as landfill gas and anaerobic digester gas. It documents the known deleterious effects on fuel cells, and the maximum allowable concentrations of select impurities suggested by manufacturers and researchers. The literature review helped to identify the impurity removal strategies that are available, and their effectiveness, capacity, and cost. A generic model of a stationary fuel-cell based power plant operating on digester and landfill gas has been developed; it includes a gas processing unit, followed by a fuel cell system. The model includes the key impurity removal steps to enable predictions of impurity breakthrough

  6. Thermal Heat and Power Production with Models for Local and Regional Energy Systems

    Energy Technology Data Exchange (ETDEWEB)

    Saether, Sturla

    1999-07-01

    The primary goal of this thesis is the description and modelling of combined heat and power systems as well as analyses of thermal dominated systems related to benefits of power exchange. Large power plants with high power efficiency (natural gas systems) and heat production in local heat pumps can be favourable in areas with low infrastructure of district heating systems. This system is comparable with typical combined heat and power (CHP) systems based on natural gas with respect to efficient use of fuel energy. The power efficiency obtainable from biomass and municipal waste is relatively low and the advantage of CHP for this system is high compared to pure power production with local heat pumps for heat generation. The advantage of converting pure power systems into CHP systems is best for power systems with low power efficiency and heat production at low temperature. CHP systems are divided into two main groups according to the coupling of heat and power production. Some CHP systems, especially those with strong coupling between heat and power production, may profit from having a thermal heat storage subsystem. District heating temperatures direct the heat to power ratio of the CHP units. The use of absorption chillers driven by district heating systems are also evaluated with respect to enhancing the utilisation of district heating in periods of low heat demand. Power exchange between a thermal dominated and hydropower system is found beneficial. Use of hydropower as a substitute for peak power production in thermal dominated systems is advantageous. Return of base load from the thermal dominated system to the hydropower system can balance in the net power exchange.

  7. Regulation of stem cells in the zebra fish hematopoietic system.

    Science.gov (United States)

    Huang, H-T; Zon, L I

    2008-01-01

    Hematopoietic stem cells (HSCs) have been used extensively as a model for stem cell biology. Stem cells share the ability to self-renew and differentiate into multiple cell types, making them ideal candidates for tissue regeneration or replacement therapies. Current applications of stem cell technology are limited by our knowledge of the molecular mechanisms that control their proliferation and differentiation, and various model organisms have been used to fill these gaps. This chapter focuses on the contributions of the zebra fish model to our understanding of stem cell regulation within the hematopoietic system. Studies in zebra fish have been valuable for identifying new genetic and signaling factors that affect HSC formation and development with important implications for humans, and new advances in the zebra fish toolbox will allow other aspects of HSC behavior to be investigated as well, including migration, homing, and engraftment.

  8. SBR-Blood: systems biology repository for hematopoietic cells.

    Science.gov (United States)

    Lichtenberg, Jens; Heuston, Elisabeth F; Mishra, Tejaswini; Keller, Cheryl A; Hardison, Ross C; Bodine, David M

    2016-01-01

    Extensive research into hematopoiesis (the development of blood cells) over several decades has generated large sets of expression and epigenetic profiles in multiple human and mouse blood cell types. However, there is no single location to analyze how gene regulatory processes lead to different mature blood cells. We have developed a new database framework called hematopoietic Systems Biology Repository (SBR-Blood), available online at http://sbrblood.nhgri.nih.gov, which allows user-initiated analyses for cell type correlations or gene-specific behavior during differentiation using publicly available datasets for array- and sequencing-based platforms from mouse hematopoietic cells. SBR-Blood organizes information by both cell identity and by hematopoietic lineage. The validity and usability of SBR-Blood has been established through the reproduction of workflows relevant to expression data, DNA methylation, histone modifications and transcription factor occupancy profiles. PMID:26590403

  9. Automotive Fuel Processor Development and Demonstration with Fuel Cell Systems

    Energy Technology Data Exchange (ETDEWEB)

    Nuvera Fuel Cells

    2005-04-15

    The potential for fuel cell systems to improve energy efficiency and reduce emissions over conventional power systems has generated significant interest in fuel cell technologies. While fuel cells are being investigated for use in many applications such as stationary power generation and small portable devices, transportation applications present some unique challenges for fuel cell technology. Due to their lower operating temperature and non-brittle materials, most transportation work is focusing on fuel cells using proton exchange membrane (PEM) technology. Since PEM fuel cells are fueled by hydrogen, major obstacles to their widespread use are the lack of an available hydrogen fueling infrastructure and hydrogen's relatively low energy storage density, which leads to a much lower driving range than conventional vehicles. One potential solution to the hydrogen infrastructure and storage density issues is to convert a conventional fuel such as gasoline into hydrogen onboard the vehicle using a fuel processor. Figure 2 shows that gasoline stores roughly 7 times more energy per volume than pressurized hydrogen gas at 700 bar and 4 times more than liquid hydrogen. If integrated properly, the fuel processor/fuel cell system would also be more efficient than traditional engines and would give a fuel economy benefit while hydrogen storage and distribution issues are being investigated. Widespread implementation of fuel processor/fuel cell systems requires improvements in several aspects of the technology, including size, startup time, transient response time, and cost. In addition, the ability to operate on a number of hydrocarbon fuels that are available through the existing infrastructure is a key enabler for commercializing these systems. In this program, Nuvera Fuel Cells collaborated with the Department of Energy (DOE) to develop efficient, low-emission, multi-fuel processors for transportation applications. Nuvera's focus was on (1) developing fuel

  10. Energy system analysis of marginal electricity supply in consequential LCA

    DEFF Research Database (Denmark)

    Lund, Henrik; Mathiesen, Brian Vad; Christensen, Per;

    2010-01-01

    and power (CHP) and fluctuating renewable energy sources, such issue becomes very important. Materials and methods This paper identifies a business-as-usual (BAU) 2030 projection of the Danish energy system. With a high share of both CHP and wind power, such system can be regarded a front...... and their individual marginal production costs. Detailed energy system analysis (ESA) simulation is used to identify the affected technologies, considering the fact that the marginal technology will change from one hour to another, depending on the size of electricity demand compared to, among others, wind power...... and CHP productions. On the basis of such input, a long-term yearly average marginal (YAM) technology is identified and the environmental impacts are calculated using data from ecoinvent. Results The results show how the marginal electricity production is not based solely on the marginal change...

  11. Tip cell-derived RTK signaling initiates cell movements in the Drosophila stomatogastric nervous system anlage.

    Science.gov (United States)

    González-Gaitán, M; Jäckle, H

    2000-10-01

    The stomatogastric nervous system (SNS) of Drosophila is a simply organized neural circuitry that innervates the anterior enteric system. Unlike the central and the peripheral nervous systems, the SNS derives from a compact epithelial anlage in which three invagination centers, each giving rise to an invagination fold headed by a tip cell, are generated. Tip cell selection involves lateral inhibition, a process in which Wingless (Wg) activity adjusts the range of Notch signaling. Here we show that RTK signaling mediated by the Drosophila homolog of the epidermal growth factor receptor, DER, plays a key role in two consecutive steps during early SNS development. Like Wg, DER signaling participates in adjusting the range of Notch-dependent lateral inhibition during tip cell selection. Subsequently, tip cells secrete the DER ligand Spitz and trigger local RTK signaling, which initiates morphogenetic movements resulting in the tip cell-directed invaginations within the SNS anlage.

  12. Real space Dynamical Super Cell Approximation for interacting disordered systems

    OpenAIRE

    Moradian, Rostam

    2004-01-01

    Effective medium super-cell approximation method which is introduced for disordered systems is extended to a general case of interacting disordered systems. We found that the dynamical cluster approximation (DCA) and also the non local coherent potential approximation (NLCPA) are two simple case of this technique. Whole equations of this formalism derived by using the effective medium theory in real space.

  13. A simple model system enabling human CD34(+ cells to undertake differentiation towards T cells.

    Directory of Open Access Journals (Sweden)

    Antonio Lapenna

    Full Text Available BACKGROUND: Channelling the development of haematopoietic progenitor cells into T lymphocytes is dependent upon a series of extrinsic prompts whose temporal and spatial sequence is critical for a productive outcome. Simple models of human progenitor cells development depend in the main on the use of xenogeneic systems which may provide some limitations to development. METHODS AND FINDINGS: Here we provide evidence that a simple model system which utilises both human keratinocyte and fibroblast cell lines arrayed on a synthetic tantalum coated matrix provides a permissive environment for the development of human CD34⁺ haematopoietic cells into mature CD4⁺ or CD8⁺ T lymphocytes in the presence of Interleukin 7 (IL-7, Interleukin 15 (IL-15 and the Fms-like tyrosine kinase 3 ligand (Flt-3L. This system was used to compare the ability of CD34(+ cells to produce mature thymocytes and showed that whilst these cells derived from cord blood were able to productively differentiate into thymocytes the system was not permissive for the development of CD34(+ cells from adult peripheral blood. CONCLUSIONS/SIGNIFICANCE: Our study provides direct evidence for the capacity of human cord blood CD34(+ cells to differentiate along the T lineage in a simple human model system. Productive commitment of the CD34⁺ cells to generate T cells was found to be dependent on a three-dimensional matrix which induced the up-regulation of the Notch delta-like ligand 4 (Dll-4 by epithelial cells.

  14. Development of bioengineering system for stem cell proliferation

    Science.gov (United States)

    Park, H. S.; Shah, R.; Shah, C.

    2016-08-01

    From last decades, intensive research in the field of stem cells proliferation had been promoted due to the unique property of stem cells to self-renew themselves into multiples and has potential to replicate into an organ or tissues and so it's highly demanding though challenging. Bioreactor, a mechanical device, works as a womb for stem cell proliferation by providing nutritious environment for the proper growth of stem cells. Various factors affecting stem cells growth are the bioreactor mechanism, feeding of continuous nutrients, healthy environment, etc., but it always remains a challenge for controlling biological parameters. The present paper unveils the design of mechanical device commonly known as bioreactor in tissues engineering and biotech field, use for proliferation of stem cells and imparts the proper growing condition for stem cells. This high functional bioreactor provides automation mixing of cell culture and stem cells. This design operates in conjunction with mechanism of reciprocating motion. Compare to commercial bioreactors, this proposed design is more convenient, easy to operate and less maintenance is required as bioreactor culture bag is made of polyethylene which is single use purpose. Development of this bioengineering system will be beneficial for better growth and expansion of stem cell

  15. B-lymphocyte lineage cells and the respiratory system.

    Science.gov (United States)

    Kato, Atsushi; Hulse, Kathryn E; Tan, Bruce K; Schleimer, Robert P

    2013-04-01

    Adaptive humoral immune responses in the airways are mediated by B cells and plasma cells that express highly evolved and specific receptors and produce immunoglobulins of most isotypes. In some cases, such as autoimmune diseases or inflammatory diseases caused by excessive exposure to foreign antigens, these same immune cells can cause disease by virtue of overly vigorous responses. This review discusses the generation, differentiation, signaling, activation, and recruitment pathways of B cells and plasma cells, with special emphasis on unique characteristics of subsets of these cells functioning within the respiratory system. The primary sensitization events that generate B cells responsible for effector responses throughout the airways usually occur in the upper airways, tonsils, and adenoid structures that make up the Waldeyer ring. On secondary exposure to antigen in the airways, antigen-processing dendritic cells migrate into secondary lymphoid organs, such as lymph nodes, that drain the upper and lower airways, and further B-cell expansion takes place at those sites. Antigen exposure in the upper or lower airways can also drive expansion of B-lineage cells in the airway mucosal tissue and lead to the formation of inducible lymphoid follicles or aggregates that can mediate local immunity or disease. PMID:23540615

  16. B lymphocyte lineage cells and the respiratory system

    Science.gov (United States)

    Kato, Atsushi; Hulse, Kathryn E.; Tan, Bruce K.; Schleimer, Robert P.

    2013-01-01

    Adaptive humoral immune responses in the airways are mediated by B cells and plasma cells that express highly evolved and specific receptors and produce immunoglobulins of most isotypes. In some cases, such as autoimmune diseases or inflammatory diseases caused by excessive exposure to foreign antigens, these same immune cells can cause disease by virtue of overly vigorous responses. This review discusses the generation, differentiation, signaling, activation and recruitment pathways of B cells and plasma cells, with special emphasis on unique characteristics of subsets of these cells functioning within the respiratory system. The primary sensitization events that generate B cells responsible for effector responses throughout the airways usually occur in the upper airways, in tonsils and adenoid structures that make up Waldeyer’s Ring. Upon secondary exposure to antigen in the airways, antigen-processing dendritic cells migrate into secondary lymphoid organs such as lymph nodes that drain the upper and lower airways and further B cell expansion takes place at those sites. Antigen exposure in the upper or lower airways can also drive expansion of B lineage cells in the airway mucosal tissue and lead to the formation of inducible lymphoid follicles or aggregates that can mediate local immunity or disease. PMID:23540615

  17. Renal cell carcinoma arising in ipsilateral duplex system.

    Science.gov (United States)

    Mohan, Harsh; Kundu, Reetu; Dalal, Usha

    2014-09-01

    Congenital anomalies of the kidney and urinary tract are common and include a wide anatomic spectrum. Duplex systems are one of the more common renal anomalies, with the majority being asymptomatic. Little is known about the molecular pathogenesis of these anomalies; however, certain causative genes have been implicated. The finding of renal cell carcinoma arising in a kidney with the duplication of pelvicalyceal system and ureters, as in the present case, is uncommon. The association between a duplex system and renal cell carcinoma may be more than a coincidence, requiring a deeper insight and further elucidation. PMID:26328175

  18. Cell culture monitoring by impedance mapping using a multielectrode scanning impedance spectroscopy system (CellMap)

    International Nuclear Information System (INIS)

    We report on the impedance mapping of in vitro cellular morphology by electrical impedance spectroscopy, using microelectrodes. A micro multielectrode system was designed, fabricated, assembled, tested and demonstrated for the monitoring of anchorage-dependent cell behavior and morphology. This system allowed continuous, label-free, quantitative monitoring and visualization of cell adhesion, spreading, proliferation and detachment due to cell cycle processes as well as cell–drug interaction, with spatio-temporal resolution. OvCa429 ovarian cancer cells were monitored in vitro over a period of 70 hours by inoculating the cell suspension directly on the multielectrode device. The phase angle of impedance was observed to develop a distinctive shape as a result of cell attachment and proliferation. The shape of the phase angle curve reverted back to the pre-attachment shape upon detachment of cells from the substrate, caused by the addition of trypsin to the cell culture medium. The impedance data of the cell culture were then successfully modeled as a multi-parametric equivalent circuit. The model incorporated both interfacial and cell-layer impedance parameters. Upon addition of trypsin, the cell-layer parameters showed a marked decline and were eventually eliminated from the multi-parametric model, confirming the correlation of the model to the electrode–cell–electrolyte system. These experiments demonstrate the applicability of the impedance mapping technique in visualizing and quantifying physiological changes in the cell layer due to cellular processes as well as the effect of external chemical stimulus on cells (cell–drug interaction)

  19. [Microglial cells and development of the embryonic central nervous system].

    Science.gov (United States)

    Legendre, Pascal; Le Corronc, Hervé

    2014-02-01

    Microglia cells are the macrophages of the central nervous system with a crucial function in the homeostasis of the adult brain. However, recent studies showed that microglial cells may also have important functions during early embryonic central nervous system development. In this review we summarize recent works on the extra embryonic origin of microglia, their progenitor niche, the pattern of their invasion of the embryonic central nervous system and on interactions between embryonic microglia and their local environment during invasion. We describe microglial functions during development of embryonic neuronal networks, including their roles in neurogenesis, in angiogenesis and developmental cell death. These recent discoveries open a new field of research on the functions of neural-microglial interactions during the development of the embryonic central nervous system.

  20. Stochastic Placement and Sizing of Combined Heat and Power Systems Considering Cost/Benefit Analysis

    Directory of Open Access Journals (Sweden)

    S. Mehrdad Hosseini

    2013-01-01

    Full Text Available This study presents a cost/worth analysis approach for optimal Placement and sizing of Combined Heat and Power (CHP systems. Particle Swarm Optimization (PSO as a powerful optimization technique is employed for optimization. Different benefits brought up by CHP systems are taken into account as a multi-objective decision making. Economical factors such as power and heat selling, reliability improvement, loss reduction, deferred upgrading investment and CHP costs are considered in this study. In order to incorporate stochastic nature of power system in this study, Monte-Carlo method is used to simulate the effect of uncertainty of loads and system on the optimal location and size of the CHPs in the network. This study conducts two separate case studies, 6-bus meshed test system and 14-bus radial test system to demonstrate economical feasibility for investment planning when cost and CHP benefits are taken into account. The impacts of considering different parameters such as the rate of load growth and interest are studied. Results indicate that the proposed methodology is capable of finding the best location and the optimal size of CHP that can cause improvement in network operation along with financial benefits

  1. Stem cell-derived systems in toxicology assessment.

    Science.gov (United States)

    Suter-Dick, Laura; Alves, Paula M; Blaauboer, Bas J; Bremm, Klaus-Dieter; Brito, Catarina; Coecke, Sandra; Flick, Burkhard; Fowler, Paul; Hescheler, Jürgen; Ingelman-Sundberg, Magnus; Jennings, Paul; Kelm, Jens M; Manou, Irene; Mistry, Pratibha; Moretto, Angelo; Roth, Adrian; Stedman, Donald; van de Water, Bob; Beilmann, Mario

    2015-06-01

    Industrial sectors perform toxicological assessments of their potential products to ensure human safety and to fulfill regulatory requirements. These assessments often involve animal testing, but ethical, cost, and time concerns, together with a ban on it in specific sectors, make appropriate in vitro systems indispensable in toxicology. In this study, we summarize the outcome of an EPAA (European Partnership of Alternatives to Animal Testing)-organized workshop on the use of stem cell-derived (SCD) systems in toxicology, with a focus on industrial applications. SCD systems, in particular, induced pluripotent stem cell-derived, provide physiological cell culture systems of easy access and amenable to a variety of assays. They also present the opportunity to apply the vast repository of existing nonclinical data for the understanding of in vitro to in vivo translation. SCD systems from several toxicologically relevant tissues exist; they generally recapitulate many aspects of physiology and respond to toxicological and pharmacological interventions. However, focused research is necessary to accelerate implementation of SCD systems in an industrial setting and subsequent use of such systems by regulatory authorities. Research is required into the phenotypic characterization of the systems, since methods and protocols for generating terminally differentiated SCD cells are still lacking. Organotypical 3D culture systems in bioreactors and microscale tissue engineering technologies should be fostered, as they promote and maintain differentiation and support coculture systems. They need further development and validation for their successful implementation in toxicity testing in industry. Analytical measures also need to be implemented to enable compound exposure and metabolism measurements for in vitro to in vivo extrapolation. The future of SCD toxicological tests will combine advanced cell culture technologies and biokinetic measurements to support regulatory and

  2. A universal piezo-driven ultrasonic cell microinjection system.

    Science.gov (United States)

    Huang, Haibo; Mills, James K; Lu, Cong; Sun, Dong

    2011-08-01

    Over the past decade, the rapid development of biotechnologies such as gene injection, in-vitro fertilization, intracytoplasmic sperm injection (ICSI) and drug development have led to great demand for highly automated, high precision equipment for microinjection. Recently a new cell injection technology using piezo-driven pipettes with a very small mercury column was proposed and successfully applied in ICSI to a variety of mammal species. Although this technique significantly improves the survival rates of the ICSI process, shortcomings due to the toxicity of mercury and damage to the cell membrane due to large lateral tip oscillations of the injector pipette may limit its application. In this paper, a new cell injection system for automatic batch injection of suspended cells is developed. A new design of the piezo-driven cell injector is proposed for automated suspended cell injection. This new piezo-driven cell injector design relocates the piezo oscillation actuator to the injector pipette which eliminates the vibration effect on other parts of the micromanipulator. A small piezo stack is sufficient to perform the cell injection process. Harmful lateral tip oscillations of the injector pipette are reduced substantially without the use of a mercury column. Furthermore, ultrasonic vibration micro-dissection (UVM) theory is utilized to analyze the piezo-driven cell injection process, and the source of the lateral oscillations of the injector pipette is investigated. From preliminary experiments of cell injection of a large number of zebrafish embryos (n = 200), the injector pipette can easily pierce through the cell membrane at a low injection speed and almost no deformation of the cell wall, and with a high success rate(96%) and survival rate(80.7%) This new injection approach shows good potential for precision injection with less damage to the injected cells.

  3. The thioredoxin system in breast cancer cell invasion and migration

    Directory of Open Access Journals (Sweden)

    Maneet Bhatia

    2016-08-01

    Full Text Available Metastasis is the most life threatening aspect of breast cancer. It is a multi-step process involving invasion and migration of primary tumor cells with a subsequent colonization of these cells at a secondary location. The aim of the present study was to investigate the role of thioredoxin (Trx1 in the invasion and migration of breast cancer cells and to assess the strength of the association between high levels of Trx1 and thioredoxin reductase (TrxR1 expression with breast cancer patient survival. Our results indicate that the expression of both Trx1 and TrxR1 are statistically significantly increased in breast cancer patient cells compared with paired normal breast tissue from the same patient. Over-expression of Trx1 in MDA-MB-231 breast cancer cell lines enhanced cell invasion in in vitro assays while expression of a redox inactive mutant form of Trx1 (designated 1SS or the antisense mRNA inhibited cell invasion. Addition of exogenous Trx1 also enhanced cell invasion, while addition of a specific monoclonal antibody that inhibits Trx1 redox function decreased cell invasion. Over-expression of intracellular Trx1 did not increase cell migration but expression of intracellular 1SS inhibited migration. Addition of exogenous Trx1 enhanced cell migration while 1SS had no effect. Treatment with auranofin inhibited TrxR activity, cell migration and clonogenic activity of MDA-MB-231 cells, while increasing reactive oxygen species (ROS levels. Analysis of 25 independent cohorts with 5910 patients showed that Trx1 and TrxR1 were both associated with a poor patient prognosis in terms of overall survival, distant metastasis free survival and disease free survival. Therefore, targeting the Trx system with auranofin or other specific inhibitors may provide improved breast cancer patient outcomes through inhibition of cancer invasion and migration.

  4. The thioredoxin system in breast cancer cell invasion and migration.

    Science.gov (United States)

    Bhatia, Maneet; McGrath, Kelly L; Di Trapani, Giovanna; Charoentong, Pornpimol; Shah, Fenil; King, Mallory M; Clarke, Frank M; Tonissen, Kathryn F

    2016-08-01

    Metastasis is the most life threatening aspect of breast cancer. It is a multi-step process involving invasion and migration of primary tumor cells with a subsequent colonization of these cells at a secondary location. The aim of the present study was to investigate the role of thioredoxin (Trx1) in the invasion and migration of breast cancer cells and to assess the strength of the association between high levels of Trx1 and thioredoxin reductase (TrxR1) expression with breast cancer patient survival. Our results indicate that the expression of both Trx1 and TrxR1 are statistically significantly increased in breast cancer patient cells compared with paired normal breast tissue from the same patient. Over-expression of Trx1 in MDA-MB-231 breast cancer cell lines enhanced cell invasion in in vitro assays while expression of a redox inactive mutant form of Trx1 (designated 1SS) or the antisense mRNA inhibited cell invasion. Addition of exogenous Trx1 also enhanced cell invasion, while addition of a specific monoclonal antibody that inhibits Trx1 redox function decreased cell invasion. Over-expression of intracellular Trx1 did not increase cell migration but expression of intracellular 1SS inhibited migration. Addition of exogenous Trx1 enhanced cell migration while 1SS had no effect. Treatment with auranofin inhibited TrxR activity, cell migration and clonogenic activity of MDA-MB-231 cells, while increasing reactive oxygen species (ROS) levels. Analysis of 25 independent cohorts with 5910 patients showed that Trx1 and TrxR1 were both associated with a poor patient prognosis in terms of overall survival, distant metastasis free survival and disease free survival. Therefore, targeting the Trx system with auranofin or other specific inhibitors may provide improved breast cancer patient outcomes through inhibition of cancer invasion and migration.

  5. The thioredoxin system in breast cancer cell invasion and migration.

    Science.gov (United States)

    Bhatia, Maneet; McGrath, Kelly L; Di Trapani, Giovanna; Charoentong, Pornpimol; Shah, Fenil; King, Mallory M; Clarke, Frank M; Tonissen, Kathryn F

    2016-08-01

    Metastasis is the most life threatening aspect of breast cancer. It is a multi-step process involving invasion and migration of primary tumor cells with a subsequent colonization of these cells at a secondary location. The aim of the present study was to investigate the role of thioredoxin (Trx1) in the invasion and migration of breast cancer cells and to assess the strength of the association between high levels of Trx1 and thioredoxin reductase (TrxR1) expression with breast cancer patient survival. Our results indicate that the expression of both Trx1 and TrxR1 are statistically significantly increased in breast cancer patient cells compared with paired normal breast tissue from the same patient. Over-expression of Trx1 in MDA-MB-231 breast cancer cell lines enhanced cell invasion in in vitro assays while expression of a redox inactive mutant form of Trx1 (designated 1SS) or the antisense mRNA inhibited cell invasion. Addition of exogenous Trx1 also enhanced cell invasion, while addition of a specific monoclonal antibody that inhibits Trx1 redox function decreased cell invasion. Over-expression of intracellular Trx1 did not increase cell migration but expression of intracellular 1SS inhibited migration. Addition of exogenous Trx1 enhanced cell migration while 1SS had no effect. Treatment with auranofin inhibited TrxR activity, cell migration and clonogenic activity of MDA-MB-231 cells, while increasing reactive oxygen species (ROS) levels. Analysis of 25 independent cohorts with 5910 patients showed that Trx1 and TrxR1 were both associated with a poor patient prognosis in terms of overall survival, distant metastasis free survival and disease free survival. Therefore, targeting the Trx system with auranofin or other specific inhibitors may provide improved breast cancer patient outcomes through inhibition of cancer invasion and migration. PMID:26760912

  6. Onsite Distributed Generation Systems For Laboratories, Laboratories for the 21st Century: Best Practices (Brochure)

    Energy Technology Data Exchange (ETDEWEB)

    2011-09-01

    This guide provides general information on implementing onsite distributed generation systems in laboratory environments. Specific technology applications, general performance information, and cost data are provided to educate and encourage laboratory energy managers to consider onsite power generation or combined heat and power (CHP) systems for their facilities. After conducting an initial screening, energy managers are encouraged to conduct a detailed feasibility study with actual cost and performance data for technologies that look promising. Onsite distributed generation systems are small, modular, decentralized, grid-connected, or off-grid energy systems. These systems are located at or near the place where the energy is used. These systems are also known as distributed energy or distributed power systems. DG technologies are generally considered those that produce less than 20 megawatts (MW) of power. A number of technologies can be applied as effective onsite DG systems, including: (1) Diesel, natural gas, and dual-fuel reciprocating engines; (2) Combustion turbines and steam turbines; (3) Fuel cells; (4) Biomass heating; (5) Biomass combined heat and power; (6) Photovoltaics; and (7) Wind turbines. These systems can provide a number of potential benefits to an individual laboratory facility or campus, including: (1) High-quality, reliable, and potentially dispatchable power; (2) Low-cost energy and long-term utility cost assurance, especially where electricity and/or fuel costs are high; (3) Significantly reduced greenhouse gas (GHG) emissions. Typical CHP plants reduce onsite GHG by 40 to 60 percent; (4) Peak demand shaving where demand costs are high; (5) CHP where thermal energy can be used in addition to electricity; (6) The ability to meet standby power needs, especially where utility-supplied power is interrupted frequently or for long periods and where standby power is required for safety or emergencies; and (7) Use for standalone or off

  7. Quantitative Analysis of AGV System in FMS Cell Layout

    OpenAIRE

    B Ramana; S. Sudhakara Reddy; B. Ramprasad

    1997-01-01

    Material handling is a specialised activity for a modern manufacturing concern. Automated guided vehicles (AGVs) are invariably used for material handling in flexible manufacturing Systems (FMSs) due to their flexibility. The quantitative analysis of an AGV system is useful for determining the material flow rates, operation times, length of delivery, length of empty move of AGV and the number of AGVs required for a typical FMS cell layout. The efficiency of the material handling system...

  8. Improving the performance of solid oxide fuel cell systems

    OpenAIRE

    Halinen, Matias

    2015-01-01

    Solid oxide fuel cell (SOFC) systems can provide power production at a high electrical efficiency and with very low emissions. Furthermore, they retain their high electrical efficiency over a wide range of output power and offer good fuel flexibility, which makes them well suited for a range of applications. Currently SOFC systems are under investigation by researchers as well as being developed by industrial manufacturers. The first commercial SOFC systems have been on the market for some...

  9. Dynamic modeling of a photovoltaic hydrogen fuel cell hybrid system

    Energy Technology Data Exchange (ETDEWEB)

    Hwang, J.J.; Lai, L.K. [Department of Greenergy, National University of Tainan, Tainan 700 (China); Wu, W. [Department of Chemical and Materials Engineering, National Yunlin University of Science and Technology, Yunlin 640 (China); Chang, W.R. [Department of Landscape Architecture, Fu Jen Catholic University, Taipei 242 (China)

    2009-12-15

    The objective of this paper is to mathematically model a stand-alone renewable power system, referred to as ''Photovoltaic-Fuel Cell (PVFC) hybrid system'', which maximizes the use of a renewable energy source. It comprises a photovoltaic generator (PV), a water electrolyzer, a hydrogen tank, and a proton exchange membrane (PEM) fuel cell generator. A multi-domain simulation platform Simplorer is employed to model the PVFC hybrid systems. Electrical power from the PV generator meets the user loads when there is sufficient solar radiation. The excess power from the PV generator is then used for water electrolysis to produce hydrogen. The fuel cell generator works as a backup generator to supplement the load demands when the PV energy is deficient during a period of low solar radiation, which keeps the system's reliability at the same level as for the conventional system. Case studies using the present model have shown that the present hybrid system has successfully tracked the daily power consumption in a typical family. It also verifies the effectiveness of the proposed management approach for operation of a stand-alone hybrid system, which is essential for determining a control strategy to ensure efficient and reliable operation of each part of the hybrid system. The present model scheme can be helpful in the design and performance analysis of a complex hybrid-power system prior to practical realization. (author)

  10. The Pathology of T Cells in Systemic Lupus Erythematosus

    Directory of Open Access Journals (Sweden)

    Anselm Mak

    2014-01-01

    Full Text Available Systemic lupus erythematosus (SLE is characterized by the production of a wide array of autoantibodies. Thus, the condition was traditionally classified as a “B-cell disease”. Compelling evidence has however shown that without the assistance of the helper T lymphocytes, it is indeed difficult for the “helpless” B cells to become functional enough to trigger SLE-related inflammation. T cells have been recognized to be crucial in the pathogenicity of SLE through their capabilities to communicate with and offer enormous help to B cells for driving autoantibody production. Recently, a number of phenotypic and functional alterations which increase the propensity to trigger lupus-related inflammation have been identified in lupus T cells. Here, potential mechanisms involving alterations in T-cell receptor expressions, postreceptor downstream signalling, epigenetics, and oxidative stress which favour activation of lupus T cells will be discussed. Additionally, how regulatory CD4+, CD8+, and γδ T cells tune down lupus-related inflammation will be highlighted. Lastly, while currently available outcomes of clinical trials evaluating therapeutic agents which manipulate the T cells such as calcineurin inhibitors indicate that they are at least as efficacious and safe as conventional immunosuppressants in treating lupus glomerulonephritis, larger clinical trials are undoubtedly required to validate these as-yet favourable findings.

  11. Fuel Cell System for Transportation -- 2005 Cost Estimate

    Energy Technology Data Exchange (ETDEWEB)

    Wheeler, D.

    2006-10-01

    Independent review report of the methodology used by TIAX to estimate the cost of producing PEM fuel cells using 2005 cell stack technology. The U.S. Department of Energy (DOE) Hydrogen, Fuel Cells and Infrastructure Technologies Program Manager asked the National Renewable Energy Laboratory (NREL) to commission an independent review of the 2005 TIAX cost analysis for fuel cell production. The NREL Systems Integrator is responsible for conducting independent reviews of progress toward meeting the DOE Hydrogen Program (the Program) technical targets. An important technical target of the Program is the proton exchange membrane (PEM) fuel cell cost in terms of dollars per kilowatt ($/kW). The Program's Multi-Year Program Research, Development, and Demonstration Plan established $125/kW as the 2005 technical target. Over the last several years, the Program has contracted with TIAX, LLC (TIAX) to produce estimates of the high volume cost of PEM fuel cell production for transportation use. Since no manufacturer is yet producing PEM fuel cells in the quantities needed for an initial hydrogen-based transportation economy, these estimates are necessary for DOE to gauge progress toward meeting its targets. For a PEM fuel cell system configuration developed by Argonne National Laboratory, TIAX estimated the total cost to be $108/kW, based on assumptions of 500,000 units per year produced with 2005 cell stack technology, vertical integration of cell stack manufacturing, and balance-of-plant (BOP) components purchased from a supplier network. Furthermore, TIAX conducted a Monte Carlo analysis by varying ten key parameters over a wide range of values and estimated with 98% certainty that the mean PEM fuel cell system cost would be below DOE's 2005 target of $125/kW. NREL commissioned DJW TECHNOLOGY, LLC to form an Independent Review Team (the Team) of industry fuel cell experts and to evaluate the cost estimation process and the results reported by TIAX. The results of

  12. Fuzzy Sliding Mode Control for a Fuel Cell System

    Directory of Open Access Journals (Sweden)

    Liping Fan

    2013-05-01

    Full Text Available Fuel cell powered systems have low voltage and high current output characteristics. Therefore, the output voltage of the fuel cell must be stepped up by DC-DC converter. In this paper an integrated mathematical model for proton exchange membrane fuel cell power system with DC-DC converter is described by analyzing the working mechanism of the proton exchange membrane fuel cell and the boost DC-DC converter. Fuzzy sliding mode control scheme is proposed to realize stable output voltage under different loads. Simulation operations are carried out and results are compared with fuzzy control and sliding mode control. It is shown that the use of the proposed fuzzy sliding mode controller can achieve good control effect.

  13. Design of a Fuel Cell Hybrid Electric Vehicle Drive System

    DEFF Research Database (Denmark)

    Schaltz, Erik

    supply system of the truck which was powered by a lead-acid battery package. The FCSPP includes fuel storage, a fuel cell system, an energy storage device, power electronics, an electric machine, and the necessary control. The FCSPP therefore converts the energy of the fuel to a shaft torque and speed...... of the electric machine. In the thesis the High Temperature Proton Exchange Membrane Fuel Cell (HTPEMFC) is used as it has promising properties for being supplied by reformed methanol, instead of pure hydrogen, which is more practical feasible. It takes approximately 6 minutes before the fuel cell is ready...... to produce power. In this period an energy storage device is necessary in order to provide power for the electric machines, and to heat-up the fuel cell stack. The energy storage device also takes care of the peak loads, the high load dynamics, and it utilizes the braking energy in order to increase...

  14. T cells fail to develop in the human skin-cell explants system; an inconvenient truth

    Directory of Open Access Journals (Sweden)

    Vanderlocht Joris

    2011-02-01

    Full Text Available Abstract Background Haplo-identical hematopoietic stem cell (HSC transplantation is very successful in eradicating haematological tumours, but the long post-transplant T-lymphopenic phase is responsible for high morbidity and mortality rates. Clark et al. have described a skin-explant system capable of producing host-tolerant donor-HSC derived T-cells. Because this T-cell production platform has the potential to replenish the T-cell levels following transplantation, we set out to validate the skin-explant system. Results Following the published procedures, while using the same commercial components, it was impossible to reproduce the skin-explant conditions required for HSC differentiation towards mature T-cells. The keratinocyte maturation procedure resulted in fragile cells with minimum expression of delta-like ligand (DLL. In most experiments the generated cells failed to adhere to carriers or were quickly outcompeted by fibroblasts. Consequently it was not possible to reproduce cell-culture conditions required for HSC differentiation into functional T-cells. Using cell-lines over-expressing DLL, we showed that the antibodies used by Clark et al. were unable to detect native DLL, but instead stained 7AAD+ cells. Therefore, it is unlikely that the observed T-lineage commitment from HSC is mediated by DLL expressed on keratinocytes. In addition, we did confirm expression of the Notch-ligand Jagged-1 by keratinocytes. Conclusions Currently, and unfortunately, it remains difficult to explain the development or growth of T-cells described by Clark et al., but for the fate of patients suffering from lymphopenia it is essential to both reproduce and understand how these co-cultures really "work". Fortunately, alternative procedures to speed-up T-cell reconstitution are being established and validated and may become available for patients in the near future.

  15. Potential of Reversible Solid Oxide Cells as Electricity Storage System

    Directory of Open Access Journals (Sweden)

    Paolo Di Giorgio

    2016-08-01

    Full Text Available Electrical energy storage (EES systems allow shifting the time of electric power generation from that of consumption, and they are expected to play a major role in future electric grids where the share of intermittent renewable energy systems (RES, and especially solar and wind power plants, is planned to increase. No commercially available technology complies with all the required specifications for an efficient and reliable EES system. Reversible solid oxide cells (ReSOC working in both fuel cell and electrolysis modes could be a cost effective and highly efficient EES, but are not yet ready for the market. In fact, using the system in fuel cell mode produces high temperature heat that can be recovered during electrolysis, when a heat source is necessary. Before ReSOCs can be used as EES systems, many problems have to be solved. This paper presents a new ReSOC concept, where the thermal energy produced during fuel cell mode is stored as sensible or latent heat, respectively, in a high density and high specific heat material and in a phase change material (PCM and used during electrolysis operation. The study of two different storage concepts is performed using a lumped parameters ReSOC stack model coupled with a suitable balance of plant. The optimal roundtrip efficiency calculated for both of the configurations studied is not far from 70% and results from a trade-off between the stack roundtrip efficiency and the energy consumed by the auxiliary power systems.

  16. Non-disruptive measurement system of cell viability in bioreactors

    Science.gov (United States)

    Rudek, F.; Nelsen, B. L.; Baselt, T.; Berger, T.; Wiele, M.; Prade, I.; Hartmann, P.

    2016-04-01

    Nutrient and oxygen transport, as well as the removal of metabolic waste are essential processes to support and maintain viable tissue. Current bioreactor technology used to grow tissue cultures in vitro has a fundamental limit to the thickness of tissues. Based on the low diffusion limit of oxygen a maximum tissue thickness of 200 μm is possible. The efficiency of those systems is currently under investigation. During the cultivation process of the artificial tissue in bioreactors, which lasts 28 days or longer, there are no possibilities to investigate the viability of cells. This work is designed to determine the influence of a non-disruptive cell viability measuring system on cellular activity. The measuring system uses a natural cellular marker produced during normal metabolic activity. Nicotinamide adenine dinucleotide (NADH) is a coenzyme naturally consumed and produced during cellular metabolic processes and has thoroughly been studied to determine the metabolic state of a cell. Measuring the fluorescence of NADH within the cell represents a non-disruptive marker for cell viability. Since the measurement process is optical in nature, NADH fluorescence also provides a pathway for sampling at different measurement depths within a given tissue sample. The measurement system we are using utilizes a special UV light source, to excite the NADH fluorescence state. However, the high energy potentially alters or harms the cells. To investigate the influence of the excitation signal, the cells were irradiated with a laser operating at a wavelength of 355 nm and examined for cytotoxic effects. The aim of this study was to develop a non-cytotoxic system that is applicable for large-scale operations during drug-tissue interaction testing.

  17. Holistic Modeling, Design & Analysis of Integrated Stirling and Auxiliary Clean Energy Systems for Combined Heat and Power Applications

    Science.gov (United States)

    Nayak, Amrit Om

    The research revolves around the development of a model to design and analyze Stirling systems. Lack of a standard approach to study Stirling systems and difficulty in generalizing existing approaches pose stiff challenges. A stable mathematical model (integrated second order adiabatic and dynamic model) is devised and validated for general use. The research attempts to design compact combined heat and power (CHP) system to run on multiple biomass fuels and solar energy. Analysis is also carried out regarding the design of suitable auxiliary systems like thermal energy storage system, biomass moisture removal system and Fresnel solar collector for the CHP Stirling system.

  18. Transdifferentiation of human amniotic epithelial cells into acinar cells using a double-chamber system.

    Science.gov (United States)

    Huang, Gui-Lin; Zhang, Ni-Ni; Wang, Jun-Sheng; Yao, Li; Zhao, Yu-Jie; Wang, Yu-Ying

    2012-08-01

    This study investigated the transdifferentiation of stem cells from human amnion tissue into functional acinar cells (ACs) using a co-culture system. Human amniotic epithelial cells (hAECs) were isolated from amnion tissue by mechanical mincing and enzymatic digestion. After primary culture, the phenotype of the cells was identified by flow cytometry (FCM) and immunocytochemical staining. hAECs were co-cultured with submandibular gland acinar cells of SD rats using a double-chamber system. The expression of α-amylase was determined by immunocytochemical method and fluorescent real-time quantitative reverse transcription polymerase chain reaction (RT-PCR) after induction for 1 and 2 weeks, respectively. Digestion with trypsin is an effective method for isolating hAECs from amnion tissue. These cells were positive for CD29 and CK19 and weakly positive for CD44 and α-amylase. Within 2 weeks, α-amylase in hAECs increased with induction time. The expression of α-amylase in hAECs was increased 3.38-fold after co-culturing for 1 week. This ratio increased to 6.6-fold, and these cells were positive for mucins, after co-culturing for 2 weeks. hAECs possess the potential to differentiate into ACs in vitro. They might be a stem cell resource for clinical applications of cell replacement therapy in salivary gland dysfunction diseases. PMID:22800093

  19. Speech recognition systems on the Cell Broadband Engine

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Y; Jones, H; Vaidya, S; Perrone, M; Tydlitat, B; Nanda, A

    2007-04-20

    In this paper we describe our design, implementation, and first results of a prototype connected-phoneme-based speech recognition system on the Cell Broadband Engine{trademark} (Cell/B.E.). Automatic speech recognition decodes speech samples into plain text (other representations are possible) and must process samples at real-time rates. Fortunately, the computational tasks involved in this pipeline are highly data-parallel and can receive significant hardware acceleration from vector-streaming architectures such as the Cell/B.E. Identifying and exploiting these parallelism opportunities is challenging, but also critical to improving system performance. We observed, from our initial performance timings, that a single Cell/B.E. processor can recognize speech from thousands of simultaneous voice channels in real time--a channel density that is orders-of-magnitude greater than the capacity of existing software speech recognizers based on CPUs (central processing units). This result emphasizes the potential for Cell/B.E.-based speech recognition and will likely lead to the future development of production speech systems using Cell/B.E. clusters.

  20. Temperature dependence of photovoltaic cells, modules, and systems

    Energy Technology Data Exchange (ETDEWEB)

    Emery, K.; Burdick, J.; Caiyem, Y. [National Renewable Energy Lab., Golden, CO (United States)] [and others

    1996-05-01

    Photovoltaic (PV) cells and modules are often rated in terms of a set of standard reporting conditions defined by a temperature, spectral irradiance, and total irradiance. Because PV devices operates over a wide range of temperatures and irradiances, the temperature and irradiance related behavior must be known. This paper surveys the temperature dependence of crystalline and thin-film, state-of-the-art, research-size cells, modules, and systems measured by a variety of methods. The various error sources and measurement methods that contribute to cause differences in the temperature coefficient for a given cell or module measured with various methods are discussed.