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Sample records for cell chp system

  1. Evaluation of an alkaline fuel cell system as a micro-CHP

    International Nuclear Information System (INIS)

    Verhaert, Ivan; Mulder, Grietus; De Paepe, Michel

    2016-01-01

    Highlights: • Sensitivity analysis on system configuration of the AFC as a micro-CHP. • Flow rate in the secondary heating circuit can be used to control water management. • Part load behavior of fuel cells is compared to other micro-CHP technologies. • For future energy demand in buildings fuel cells have the best performance. - Abstract: Micro-cogeneration is an emerging technology to reduce the non-renewable energy demand in buildings and reduce peak load in the grid. Fuel cell based cogeneration (CHP) has interesting prospects for building applications, even at relatively low heat demand. This is due to their partial load behavior which is completely different, compared to other micro-CHP technologies. Within the fuel cell technologies suitable for small scale CHP or micro-CHP, the existing configuration of an alkaline fuel cell system is analyzed. This analysis is based on validated models and offers a control strategy to optimize both water management and energy performance of the alkaline fuel cell system. Finally, the model of the alkaline fuel cell system with optimized control strategy is used to compare its part load behavior to other micro-CHP technologies.

  2. Hybrid Solid Oxide Fuel Cell and Thermoelectric Generator for Maximum Power Output in Micro-CHP Systems

    DEFF Research Database (Denmark)

    Rosendahl, Lasse; Mortensen, Paw Vestergård; Enkeshafi, Ali A.

    2011-01-01

    and market segments which are not yet quantified. This paper quantifies a micro-CHP system based on a solid oxide fuel cell (SOFC) and a high-performance TE generator. Based on a 3 kW fuel input, the hybrid SOFC implementation boosts electrical output from 945 W to 1085 W, with 1794 W available for heating...... the electricity production in micro-CHP systems by more than 15%, corresponding to system electrical efficiency increases of some 4 to 5 percentage points. This will make fuel cell-based micro-CHP systems very competitive and profitable and will also open opportunities in a number of other potential business...

  3. Process Intensification in Fuel Cell CHP Systems, the ReforCELL Project

    Directory of Open Access Journals (Sweden)

    José Luis Viviente

    2016-10-01

    Full Text Available This paper reports the findings of a FP7/FCH JU project (ReforCELL that developed materials (catalysts and membranes and an advance autothermal membrane reformer for a micro Combined Heat and Power (CHP system of 5 kWel based on a polymer electrolyte membrane fuel cell (PEMFC. In this project, an active, stable and selective catalyst was developed for the reactions of interest and its production was scaled up to kg scale (TRL5 (TRL: Technology Readiness Level. Simultaneously, new membranes for gas separation were developed. In particular, dense supported thin palladium-based membranes were developed for hydrogen separation from reactive mixtures. These membranes were successfully scaled up to TRL4 and used in lab-scale reactors for fluidized bed steam methane reforming (SMR and autothermal reforming (ATR and in a prototype reactor for ATR. Suitable sealing techniques able to integrate the different membranes in lab-scale and prototype reactors were also developed. The project also addressed the design and optimization of the subcomponents (BoP for the integration of the membrane reformer to the fuel cell system.

  4. Micro-CHP systems for residential applications

    International Nuclear Information System (INIS)

    Paepe, Michel de; D'Herdt, Peter; Mertens, David

    2006-01-01

    Micro-CHP systems are now emerging on the market. In this paper, a thorough analysis is made of the operational parameters of 3 types of micro-CHP systems for residential use. Two types of houses (detached and terraced) are compared with a two storey apartment. For each building type, the energy demands for electricity and heat are dynamically determined. Using these load profiles, several CHP systems are designed for each building type. Data were obtained for two commercially available gas engines, two Stirling engines and a fuel cell. Using a dynamic simulation, including start up times, these five system types are compared to the separate energy system of a natural gas boiler and buying electricity from the grid. All CHP systems, if well sized, result in a reduction of primary energy use, though different technologies have very different impacts. Gas engines seem to have the best performance. The economic analysis shows that fuel cells are still too expensive and that even the gas engines only have a small internal rate of return (<5%), and this only occurs in favourable economic circumstances. It can, therefore, be concluded that although the different technologies are technically mature, installation costs should at least be reduced by 50% before CHP systems become interesting for residential use. Condensing gas boilers, now very popular in new homes, prove to be economically more interesting and also have a modest effect on primary energy consumption

  5. Experimental study and modeling of degradation phenomena in HTPEM fuel cell stacks for use in CHP systems

    DEFF Research Database (Denmark)

    Nielsen, Mads Pagh; Andreasen, Søren Juhl; Rasmussen, Peder Lund

    2009-01-01

    Degradation phenomena in HTPEM fuel cells for use in CHP systems were investigated experimentally and by modeling. It was found that the two main degradation mechanisms in HTPEM fuel cells are carbon corrosion and Pt agglomeration. On basis of this conclusion a mechanistic model, describing the d...

  6. Cost targets for domestic fuel cell CHP

    Science.gov (United States)

    Staffell, I.; Green, R.; Kendall, K.

    Fuel cells have the potential to reduce domestic energy bills by providing both heat and power at the point of use, generating high value electricity from a low cost fuel. However, the cost of installing the fuel cell must be sufficiently low to be recovered by the savings made over its lifetime. A computer simulation is used to estimate the savings and cost targets for fuel cell CHP systems. Two pitfalls of this kind of simulation are addressed: the selection of representative performance figures for fuel cells, and the range of houses from which energy demand data was taken. A meta-study of the current state of the art is presented, and used with 102 house-years of demand to simulate the range of economic performance expected from four fuel cell technologies within the UK domestic CHP market. Annual savings relative to a condensing boiler are estimated at €170-300 for a 1 kWe fuel cell, giving a target cost of €350-625 kW -1 for any fuel cell technology that can demonstrate a 2.5-year lifetime. Increasing lifetime and reducing fuel cell capacity are identified as routes to accelerated market entry. The importance of energy demand is seen to outweigh both economic and technical performance assumptions, while manufacture cost and system lifetime are highlighted as the only significant differences between the technologies considered. SOFC are considered to have the greatest potential, but uncertainty in the assumptions used precludes any clear-cut judgement.

  7. Heat Pumps in CHP Systems

    DEFF Research Database (Denmark)

    Ommen, Torben Schmidt

    In the current Danish energy system, the majority of electricity and heat is produced in combined heat and power (CHP) plants. With increasing shares of intermittent renewable power production, it becomes a challenging task to match power and heat production to its demand curves, as production...... that three configurations are particular advantageous, whereas the two remaining configurations result in system performance close to or below what may be expected from an electric heater. One of the three advantageous configurations is required to be positioned at the location of the heat demand, whereas....... Six vapour compression heat pump (VCHP) systems were considered along with the ammonia-water hybrid absorption compression heat pump (HACHP), corresponding to an upper limit of the sink temperature of up to 150 °C. The best available technology was determined for each set of heat sink and source...

  8. Designing and optimization of a micro CHP system based on Solid Oxide Fuel Cell with different fuel processing technologies

    DEFF Research Database (Denmark)

    Liso, Vincenzo; Nielsen, Mads Pagh; Kær, Søren Knudsen

    2009-01-01

    are the possibility to partially reform hydrocarbon in the fuel cell anode compartment and the possibility to use high quality heat for cogeneration. In this work, different configurations of solid oxide fuel cell system for decentralized electricity production are examined. The Balance of Plant (BoP) components...... of the Micro Combined Heat and Power plant (mCHP) will be identified including fuel and air supply, fuel management anode re-circulation, exhaust gas heat management, power conditioning and control system. Using mass and energy balance, different types of fuel reforming including steam reforming...... will be evaluated in terms of their energetic performance and suitability for meeting residential thermal and electric demand....

  9. Designing and optimization of a micro CHP system based on Solid Oxide Fuel Cell with different fuel processing technologies

    DEFF Research Database (Denmark)

    Liso, Vincenzo; Nielsen, Mads Pagh; Kær, Søren Knudsen

    2009-01-01

    The development of fuel cell technologies offers the opportunity to achieve significant improvements in energy conversion efficiencies at many scales. The high operating temperature (700-1000 Celsius) of Solid Oxide Fuel Cells (SOFC) has a number of consequences, the most important of which...... are the possibility to partially reform hydrocarbon in the fuel cell anode compartment and the possibility to use high quality heat for cogeneration. In this work, different configurations of solid oxide fuel cell system for decentralized electricity production are examined. The Balance of Plant (BoP) components...... of the Micro Combined Heat and Power plant (mCHP) will be identified including fuel and air supply, fuel management anode re-circulation, exhaust gas heat management, power conditioning and control system. Using mass and energy balance, different types of fuel reforming including steam reforming...

  10. Experimental study and modelling of degradation phenomena in HTPEM fuel cell stacks for use in CHP systems

    DEFF Research Database (Denmark)

    Andreasen, Søren Juhl

    2009-01-01

    Degradation phenomena in HTPEM fuel cells for use in CHP systems were investigated experimentally and by modelling. It was found that the two main degradation mechanisms in HTPEM fuel cells are carbon corrosion and Pt agglomeration. On basis of this conclusion a mechanistic model, describing...... the degradation caused by these phenomena, is suggested. Using the proposed model, information about optimum operational temperatures is derived. To investigate how the degradation propagates on stack level, a simplified stack model is developed. The model is 1-dimensional, non-isothermal, and semi......-transient (considering degradation with time). The model shows that the degradation in a stack will not progress uniformly, but occurs faster in the hot end of the stack. Furthermore, the model shows that the degradation is very dependent on stack temperature control scheme. Two experiments were conducted; a 500 hours...

  11. Deployment of FlexCHP System

    Energy Technology Data Exchange (ETDEWEB)

    Cygan, David [Gas Technology Inst., Des Plaines, IL (United States)

    2015-11-01

    The Gas Technology Institute (GTI), along with its partner Integrated CHP Systems Corporation, has developed and demonstrated an Ultra-Low-Nitrogen Oxide (ULN) Flexible Combined Heat and Power (FlexCHP) system that packages a state-of-the-art Capstone C65 gas microturbine and Johnston PFXX100 boiler with an innovative natural gas-fired supplemental burner. Supplemental burners add heat as needed in response to facility demand, which increases energy efficiency, but typically raises exhaust NOx levels, degrading local air quality unless a costly and complicated catalytic treatment system is added. The FlexCHP system increases energy efficiency and achieves the 2007 California Air Resource Board (CARB) distributed generation emissions standards for Nitrogen oxides (NOx), Carbon Monoxide (CO), and Total Hydrocarbons (THC) without catalytic exhaust gas treatment. The key to this breakthrough performance is a simple and reliable burner design which utilizes staged combustion with engineered internal recirculation. This ULN burner system successfully uses turbine exhaust as an oxidizer, while achieving high efficiencies and low emissions. In tests at its laboratory facilities in Des Plaines, Illinois, GTI validated the ability of the system to achieve emissions of NOx, CO, and THC below the CARB criteria of 0.07, 0.10, and 0.02 lb/MW-h respectively. The FlexCHP system was installed at the field demonstration site, Inland Empire Foods, in Riverside, California to verify performance of the technology in an applied environment. The resulting Combined Heat and Power (CHP) package promises to make CHP implementation more attractive, mitigate greenhouse gas emissions, and improve the reliability of electricity supply.

  12. Design considerations for effective control of an afterburner sub-system in a combined heat and power (CHP) fuel cell system (FCS)

    Science.gov (United States)

    Colella, Whitney G.

    This article investigates various control strategies for a combined heat and power (CHP) fuel cell system (FCS), with a specific focus on the afterburner sub-system. The afterburner sub-system recovers heat and by-products from the excess fuel and oxidant not consumed within the fuel cell. The overall performance of a CHP FCS depends crucially on the control of the afterburner sub-system because the control of this sub-system (1) determines the extent of thermal energy recovered from the system, between 35 and 55% of fuel energy input; (2) establishes the rate limiting step in the control of the overall CHP FCS because the rate at which the afterburner can combust excess fuel and oxidant safely and raise steam affects the rate at which the fuel cell's electrical power output can change; and (3) impacts upstream mass and energy flows strongly, such as the system's overall water balance and also the raising of steam for the upstream fuel processor and cathode humidification, as this is the point in the system where the CHP FCS becomes closed loop for heat and mass flows. Using an Aspen Plus ® chemical engineering model of the CHP FCS, this article (1) identifies potential challenges in operating the afterburner sub-system, (2) discusses various options for ameliorating those challenges, and (3) recommends viable solutions. The two challenges it discusses in detail are (1) the danger of overheating the afterburner, and (2) the danger of overheating a downstream steam generator. Regarding the first challenge, in the low anode hydrogen utilization (AHU) range (66-85%) specified by some fuel cell manufacturers, the afterburner is in danger of overheating beyond its maximum rated operating point. Regarding the second challenge, also at low anode hydrogen utilizations, the steam generator is in danger of overheating beyond its maximum rated operating point. This article demonstrates that one solution for overcoming these challenges is to dilute the afterburner's stream

  13. 330 kWe Packaged CHP System with Reduced Emissions

    Energy Technology Data Exchange (ETDEWEB)

    Plahn, Paul [Cummins Power Generation, Minneapolis, MN (United States); Keene, Kevin [Cummins Power Generation, Minneapolis, MN (United States); Pendray, John [Cummins Power Generation, Minneapolis, MN (United States)

    2015-03-31

    The objective of this project was to develop a flexible, 330 kWe packaged Combined Heat and Power (CHP) system that can be deployed to commercial and light industrial applications at a lower total cost of ownership than current CHP solutions. The project resulted in a CHP system that is easy to use and inexpensive to install, offering world class customer support, while providing a low-emissions, higher-efficiency internal combustion engine for a CHP system of this size.

  14. MICRO-CHP System for Residential Applications

    Energy Technology Data Exchange (ETDEWEB)

    Joseph Gerstmann

    2009-01-31

    This is the final report of progress under Phase I of a project to develop and commercialize a micro-CHP system for residential applications that provides electrical power, heating, and cooling for the home. This is the first phase of a three-phase effort in which the residential micro-CHP system will be designed (Phase I), developed and tested in the laboratory (Phase II); and further developed and field tested (Phase III). The project team consists of Advanced Mechanical Technology, Inc. (AMTI), responsible for system design and integration; Marathon Engine Systems, Inc. (MES), responsible for design of the engine-generator subsystem; AO Smith, responsible for design of the thermal storage and water heating subsystems; Trane, a business of American Standard Companies, responsible for design of the HVAC subsystem; and AirXchange, Inc., responsible for design of the mechanical ventilation and dehumidification subsystem.

  15. Micro-CHP Systems for Residential Applications

    Energy Technology Data Exchange (ETDEWEB)

    Timothy DeValve; Benoit Olsommer

    2007-09-30

    Integrated micro-CHP (Cooling, Heating and Power) system solutions represent an opportunity to address all of the following requirements at once: conservation of scarce energy resources, moderation of pollutant release into our environment, and assured comfort for home-owners. The objective of this effort was to establish strategies for development, demonstration, and sustainable commercialization of cost-effective integrated CHP systems for residential applications. A unified approach to market and opportunity identification, technology assessment, specific system designs, adaptation to modular product platform component conceptual designs was employed. UTRC's recommendation to U.S. Department of Energy is to go ahead with the execution of the proposed product development and commercialization strategy plan under Phase II of this effort. Recent indicators show the emergence of micro-CHP. More than 12,000 micro-CHP systems have been sold worldwide so far, around 7,500 in 2004. Market projections predict a world-wide market growth over 35% per year. In 2004 the installations were mainly in Europe (73.5%) and in Japan (26.4%). The market in North-America is almost non-existent (0.1%). High energy consumption, high energy expenditure, large spark-spread (i.e., difference between electricity and fuel costs), big square footage, and high income are the key conditions for market acceptance. Today, these conditions are best found in the states of New York, Pennsylvania, New Jersey, Wisconsin, Illinois, Indiana, Michigan, Ohio, New England states. A multiple stage development plan is proposed to address risk mitigation. These stages include concept development and supplier engagement, component development, system integration, system demonstration, and field trials. A two stage commercialization strategy is suggested based on two product versions. The first version--a heat and power system named Micro-Cogen, provides the heat and essential electrical power to the

  16. Performance study of an innovative natural gas CHP system

    International Nuclear Information System (INIS)

    Fu, Lin; Zhao, Xiling; Zhang, Shigang; Li, Yan; Jiang, Yi; Li, Hui; Sun, Zuoliang

    2011-01-01

    In the last decade, technological innovation and changes in the economic and regulatory environment have resulted in increased attention to distributed energy systems (DES). Combined cooling heating and power (CHP) systems based on the gas-powered internal combustion engine (ICE) are increasingly used as small-scale distribution co-generators. This paper describes an innovative ICE-CHP system with an exhaust-gas-driven absorption heat pump (AHP) that has been set up at the energy-saving building in Beijing, China. The system is composed of an ICE, an exhaust-gas-driven AHP, and a flue gas condensation heat exchanger (CHE), which could recover both the sensible and latent heat of the flue gas. The steady performance and dynamic response of the innovative CHP system with different operation modes were tested. The results show that the system's energy utilization efficiency could reach above 90% based on lower heating value (LHV) of natural gas; that is, the innovative CHP system could increase the heat utilization efficiency 10% compared to conventional CHP systems, and the thermally activated components of the system have much more thermal inertia than the electricity generation component. The detailed test results provide important insight into CHP performance characteristics and could be valuable references for the control of CHP systems. The novel CHP system could take on a very important role in the CHP market. (author)

  17. Modeling and simulation of a residential micro-CHP system based on HT-PEMFC technology

    DEFF Research Database (Denmark)

    Arsalis, Alexandros; Nielsen, Mads Pagh; Kær, Søren Knudsen

    2009-01-01

    Combined-heat-and-power (CHP) technology is a well known and proved method to produce simultaneously power and heat at high efficiencies. This can be further improved by the introduction of a novel micro-CHP residential system based on High Temperature-Proton Exchange Membrane Fuel Cell (HT-PEMFC......). The HT-PEMFC (based on PBI-membrane technology) operates at temperatures near 200oC, and this can be an ideal match for cogeneration residential systems. The proposed system provides electric power, hot water, and space heating for a typical household (1-5 kWe, 5-10 kWth). The micro-CHP system...

  18. Procuring Stationary Fuel Cells For CHP: A Guide for Federal Facility Decision Makers

    Energy Technology Data Exchange (ETDEWEB)

    Stinton, David P [ORNL; McGervey, Joseph [SRA International, Inc.; Curran, Scott [ORNL

    2011-11-01

    Federal agency leaders are expressing growing interest in using innovative fuel cell combined heat and power (CHP) technology at their sites, motivated by both executive branch sustainability targets and a desire to lead by example in the transition to a clean energy economy. Fuel cell CHP can deliver reliable electricity and heat with 70% to 85% efficiency. Implementing this technology can be a high efficiency, clean energy solution for agencies striving to meet ambitious sustainability requirements with limited budgets. Fuel cell CHP systems can use natural gas or renewable fuels, such as biogas. Procuring Stationary Fuel Cells for CHP: A Guide for Federal Facility Decision Makers presents an overview of the process for planning and implementing a fuel cell CHP project in a concise, step-by-step format. This guide is designed to help agency leaders turn their interest in fuel cell technology into successful installations. This guide concentrates on larger (100 kW and greater) fuel cell CHP systems and does not consider other fuel cell applications such as cars, forklifts, backup power supplies or small generators (<100 kW). Because fuel cell technologies are rapidly evolving and have high up front costs, their deployment poses unique challenges. The electrical and thermal output of the CHP system must be integrated with the building s energy systems. Innovative financing mechanisms allow agencies to make a make versus buy decision to maximize savings. This guide outlines methods that federal agencies may use to procure fuel cell CHP systems with little or no capital investment. Each agency and division, however, has its own set of procurement procedures. This guide was written as a starting point, and it defers to the reader s set of rules if differences exist. The fuel cell industry is maturing, and project developers are gaining experience in working with federal agencies. Technology improvements, cost reductions, and experienced project developers are making

  19. Modeling work of a small scale gasifier/SOFC CHP system

    Energy Technology Data Exchange (ETDEWEB)

    Liu, M.; Aravind, P.V.; Qu, Z.; Woudstra, N.; Verkooijen, A.H.M. [Delft University of Technology (Netherlands). Dept. of Mechanical Engineering], Emails: ming.liu@tudelft.nl, p.v.aravind@tudelft.nl, z.qu@tudelft.nl, n.woudstra@tudelft.nl, a. h. m. verkooijen@tudelft.nl; Cobas, V.R.M. [Federal University of Itajuba (UNIFEI), Pinheirinhos, MG (Brazil). Dept. of Mechanical Engineering], E-mail: vlad@unifei.edu.br

    2009-07-01

    For a highly efficient biomass gasification/Solid Oxide Fuel Cell (SOFC) Combined Heat and Power (CHP) generation system, the gasifier, the accompanying gas cleaning technologies and the CHP unit must be carefully designed as an integrated unit. This paper describes such a system involving a two-stage fixed-bed down draft gasifier, a SOFC CHP unit and a gas cleaning system. A gas cleaning system with both low temperature and high temperature sections is proposed for coupling the gasifier and the SOFC. Thermodynamic modeling was carried out for the gasifier/SOFC system with the proposed gas cleaning system. The net AC electrical efficiency of this system is around 30% and the overall system efficiency is around 60%. This paper also describes various exergy losses in the system and the future plans for integrated gasifier-GCU-SOFC experiments from which the results will be used to validate the modeling results of this system. (author)

  20. Local CHP Plants between the Natural Gas and Electricity Systems

    DEFF Research Database (Denmark)

    Bregnbæk, Lars; Schaumburg-Müller, Camilla

    2005-01-01

    , and they contribute significantly to the electricity production. CHP is, together with the wind power, the almost exclusive distributed generation in Denmark. This paper deals with the CHP as intermediary between the natural gas system and the electricity system. In particular, the relationship between the peak hour......Local combined heat and power (CHP) plants in Denmark constitute an important part of the national energy conversion capacity. In particular they supply a large share of the district heating networks with heat. At the same time they are important consumers as seen from the gas network system...... characteristics of the electricity and gas systems will be investigated. The point is here that the two systems will tend to have peak demand during the same hours. This is the typical situation, since load is high during the same hours of the day and of the year. Moreover, the random variations in the load...

  1. CHP systems to save money and cut carbon.

    Science.gov (United States)

    Hopkins, Ian

    2014-10-01

    According to Ian Hopkins, a director of ENER-G Combined Power--which has delivered more than 50 CHP-led energy services contracts within the healthcare sector, having, for the past 30 years, designed and manufactured CHP systems at its global headquarters and R&D centre in Salford--'the energy cost and carbon-saving benefits of combined heat and power are difficult to match where there is a large heating/cooling demand over extended periods'. In this article, he explains how hospitals and other busy healthcare facilities thus 'make ideal bedfellows' for CHP, and outlines the key criteria and considerations, such as sizing, for healthcare engineers, when looking to specify such a system.

  2. Performance of a solid oxide fuel cell CHP system coupled with a hot water storage tank for single household

    DEFF Research Database (Denmark)

    Liso, Vincenzo; Zhao, Yingru; Yang, Wenyuan

    2014-01-01

    of heat used for thermal loads of the residence. Two fuels are considered, namely syngas and natural gas. The tank model considers the temperature gradients over the tank height. The results of the numerical simulation is used to size the SOFC system and storage heat tank to provide energy for a small...... of delivering hot water for the household and returning the coldest fluid back to SOFC heat recovery heat-exchanger. A model of the SOFC system is developed to determine the energy required to meet the hourly average electric load of the residence. The model evaluates the amount of heat generated and the amount......In this paper a solid oxide fuel cell (SOFC) system for cogeneration of heat and power integrated with a stratified heat storage tank is studied. Thermal stratification in the tank increases the heat recovery performance as it allows existence of a temperature gradient with the benefit...

  3. Modelling of a solid oxide fuel cell CHP system coupled with a hot water storage tank for a single household

    DEFF Research Database (Denmark)

    Liso, Vincenzo; Zhao, Yingru; Yang, Wenyuan

    2015-01-01

    is low (for instance during the night), taking advantage of thermal stratification to increases the heat recovery performance. A model of the SOFC system is presented to estimate the energy required to meet the average electric energy demand of the residence. Two fuels are considered, namely syngas...... produced by gasification and natural gas. The tank model considers the temperature gradients over the tank height. The results of the numerical simulation are used to size the SOFC system and storage heat tank to provide energy for a small household using two different fuels. In particular it was shown...... that in the case of syngas, due to larger system heat output, a larger tank volume was required in order to accumulate unused heat over the night. The detailed description of the tank model will be useful to energy system modelers when sizing hot water tanks. Problem formulation is reported also using a Matlab...

  4. A study on electricity export capability of the μCHP system with spot price

    DEFF Research Database (Denmark)

    You, Shi; Træholt, Chresten; Poulsen, Bjarne

    2009-01-01

    When a number of muCHP systems are aggregated as a virtual power plant (VPP), they will be able to participate in the electricity wholesale market with no discrimination compared to conventional large power plants. Hence, this paper investigates the electricity export capability of the muCHP system...... when the electricity buyback price is given at a value equalizing the dynamic spot price. A muCHP system is modeled with optimized generation, and the marginal price of electricity export for such system is explained. A sensitivity analysis of several key factors, e.g. fuel price, heat to power ratio...... of the muCHP unit, which influence the export capability of muCHP system, is firstly carried out in the intraday case study, followed by the annual case study which explores the annual system performance. The results show that the electricity export capability of a muCHP system is closely related to its...

  5. Modeling and parametric study of a 1 kWe HT-PEMFC-based residential micro-CHP system

    DEFF Research Database (Denmark)

    Arsalis, Alexandros; Nielsen, Mads Pagh; Kær, Søren Knudsen

    2011-01-01

    A detailed thermodynamic, kinetic and geometric model of a micro-CHP (Combined-Heatand-Power) residential system based on High Temperature-Proton Exchange Membrane Fuel Cell (HT-PEMFC) technology is developed, implemented and validated. HT-PEMFC technology is investigated as a possible candidate...... for fuel cell-based residential micro-CHP systems, since it can operate at higher temperature than Nafion-based fuel cells, and therefore can reach higher cogeneration efficiencies. The proposed system can provide electric power, hot water, and space heating for a typical Danish single-family household....... A complete fuel processing subsystem, with all necessary balance-of-plant components, is modeled and coupled to the fuel cell stack subsystem. The micro-CHP system’s synthesis/ design and operational pattern is analyzed by means of a parametric study. The parametric study is conducted to determine the most...

  6. Optimal design and operation of a syngas-fuelled SOFC micro CHP system for residential applications in different climate zones in China

    DEFF Research Database (Denmark)

    Yang, Wenyuan; Zhao, Yingru; Liso, Vincenzo

    2014-01-01

    of the micro-CHP to cover the heat and electricity demand of a 70 m2 single-family apartment with an average number of occupants of 3 is evaluated. A detailed model of the micro-CHP unit coupled with a hot water storage tank and an auxiliary boiler is developed. System design trade-offs are discussed......Fuel cell based micro-CHP systems are expected to be one of the most promising technologies for implementation in the residential sector. Since the design and operation of such CHP systems are greatly dependent upon the seasonal atmospheric conditions, it is important to evaluate their performance...... under difference climate conditions to ensure that it is well matched with the local heat-to-power ratio. The aim of this study is to investigate the optimal design and operation of a syngas-fuelled SOFC micro-CHP system for small households located in five different climate zones in China. The ability...

  7. Assessment of the implementation issues for fuel cells in domestic and small scale stationary power generation and CHP applications

    Energy Technology Data Exchange (ETDEWEB)

    Graham, G.; Cruden, A.; Hart, J.

    2002-07-01

    This report discusses implementation issues associated with the use of fuel cells in <10 kW domestic, small-scale power generation and combined heat and power (CHP) operations in the UK. The report examines the key issues (fuel cell system standards and certification, fuel infrastructure, commercial issues and competing CHP technologies), before discussing non-technical issues including finance, ownership, import and export configuration, pricing structure, customer acceptability, installation, operation and training of servicing and commissioning personnel. The report goes on to discuss market and technical drivers, grid connection issues and solutions, operations and maintenance. Recommendations for the future are made.

  8. SOFC/TEG hybrid mCHP system. Final report

    Energy Technology Data Exchange (ETDEWEB)

    2012-03-15

    The starting point for this project have been the challenge has been to develop a cost effective solution with long term stability. This is where a focused effort in a strong consortium covering material research, module development and manufacture as well as device design and optimization can make a real difference. In March 2010 the SOFTEG phase II project was initiated and a cooperation organization was established to implement the project as a development and demonstration project involving the staff from all project partners. The project is now completed with excellent and documented outcome. The final results by Alpcon have been demonstration as a TEG-based mCHP system calls CHP Dual Engine Power System, which will be applicable as both a standalone TEG-CHP hybrid system, but also as an auxiliary power unit and power booster for the SOFC system. However the SOFC system cannot cover the household's heat demand alone so it is necessary to combine a SOFC system together with a water heater/boiler system to cover the peak heat demand of a residential house or a complex building. The SOFTEG project partners achieved significant results that mainly can be outlined as following: 1) University of Aarhus has improved the thermal stability of ZnSb by optimizing the concentration of Nano composite material. 2) The grain size and its influence on the sintering process by spark plasma method are investigated by Aarhus University, but further work seems to be necessary. 3) The TE material is going to commercialization by Aarhus University. 4) Aalborg University has prepared simulation tools for complex thermoelectric simulation in non-steady state condition. 5) The new type DCDC interleaved converter using the MPPT system for optimal power tracing is designed, build and tested by Aalborg University in cooperation with Alpcon. This task is included overall system design, control system implementation and power electronic control design. 6) Full scale practical

  9. Modeling and optimization of a 1 kWe HT-PEMFC-based micro-CHP residential system

    DEFF Research Database (Denmark)

    Arsalis, Alexandros; Nielsen, Mads Pagh; Kær, Søren Knudsen

    2012-01-01

    A high temperature-proton exchange membrane (HT-PEMFC)-based micro-combined-heat-and-power (CHP) residential system is designed and optimized, using a genetic algorithm (GA) optimization strategy. The proposed system consists of a fuel cell stack, steam methane reformer (SMR) reactor, water gas s...

  10. Combustion Turbine CHP System for Food Processing Industry

    Energy Technology Data Exchange (ETDEWEB)

    None

    2010-10-01

    This factsheet describes a combined heat and power (CHP) demonstration project that reduces the energy costs and environmental impact of a plant while easing congestion on the constrained Northeast power grid.

  11. The Role of Distributed Generation and Combined Heat and Power (CHP) Systems in Data Centers

    Science.gov (United States)

    This report reviews how distributed generation (DG) resources such as fuel cells, reciprocating engines, and gas turbines can offer powerful energy efficiency savings in data centers, particularly when configured in combined heat and power (CHP) mode.

  12. Connection of small RES and CHP power generation units to the electricity systems

    International Nuclear Information System (INIS)

    Groseva, V.

    2008-01-01

    The EU member states have to ensure to the producers of 'green' electricity guaranteed access to the electrical grid including for small installations - Directive (2001/77/EC) of EC. For this reason the European Commission (EC) supports the project 'Production of Electricity with RES and CHP for Homeowners' - PERCH, in the framework of the program 'Intelligent Energy - Europe'. In the report the issues of connection (technical, contractual, tariff and metering) are investigated for small installations using RES and micro CHP, which are owned by individual family houses, small enterprises, etc. It is pointed out that small installations, mainly PV-systems, wind generators and small CHP, as well as combination of these technologies are rapidly applied on the European market. In Bulgaria the application of small PV-systems and wind generators, as well as CHP at present is limited. The elements for encouragement of such systems are defined, as well as the barriers for their wider application. (author)

  13. Optimal Design and Operation of A Syngas-fuelled SOFC Micro-CHP System for Residential Applications in Different Climate Zones in China

    DEFF Research Database (Denmark)

    Yang, Wenyuan; Liso, Vincenzo; Zhao, Yingru

    2013-01-01

    Energy consumption in residential sector can be considerably reduced by enhancing the efficiency of energy supply. Fuel cell-based residential micro-CHP systems are expected to be one of the most promising technologies because of their high efficiency and low environmental impact. Since the design...... heat-to-power load ratio. Therefore, the aim of this study is to investigate the optimal design and operation of a syngas-fuelled SOFC micro-CHP system for small households located in five different climate zones in China. The ability of the micro-CHP to cover the heat and electricity demand of a 70m2...... single-family household with an average number of occupants of 3 is evaluated. Detailed model of the micro-CHP unit coupled with a hot water storage tank and an auxiliary boiler is developed. A transient model of the hot water storage tank is used to take into account the effect of peak residential heat...

  14. The CckA-ChpT-CtrA phosphorelay system is regulated by quorum sensing and controls flagellar motility in the marine sponge symbiont Ruegeria sp. KLH11.

    Directory of Open Access Journals (Sweden)

    Jindong Zan

    Full Text Available Bacteria respond to their environment via signal transduction pathways, often two-component type systems that function through phosphotransfer to control expression of specific genes. Phosphorelays are derived from two-component systems but are comprised of additional components. The essential cckA-chpT-ctrA phosphorelay in Caulobacter crescentus has been well studied and is important in orchestrating the cell cycle, polar development and flagellar biogenesis. Although cckA, chpT and ctrA homologues are widespread among the Alphaproteobacteria, relatively few is known about their function in the large and ecologically significant Roseobacter clade of the Rhodobacterales. In this study the cckA-chpT-ctrA system of the marine sponge symbiont Ruegeria sp. KLH11 was investigated. Our results reveal that the cckA, chpT and ctrA genes positively control flagellar biosynthesis. In contrast to C. crescentus, the cckA, chpT and ctrA genes in Ruegeria sp. KLH11 are non-essential and do not affect bacterial growth. Gene fusion and transcript analyses provide evidence for ctrA autoregulation and the control of motility-related genes. In KLH11, flagellar motility is controlled by the SsaRI system and acylhomoserine lactone (AHL quorum sensing. SsaR and long chain AHLs are required for cckA, chpT and ctrA gene expression, providing a regulatory link between flagellar locomotion and population density in KLH11.

  15. Regulatory Compliance and Environmental Benefit Analysis of Combined Heat and Power (CHP Systems in Taiwan

    Directory of Open Access Journals (Sweden)

    Wen-Tien Tsai

    2013-01-01

    Full Text Available The energy conservation achieved by utilizing waste heat in the energy and industrial sectors has became more and more important after the energy crisis in the 1970s because it plays a vital role in the potential energy-efficiency improvement. In this regard, cogeneration (combined heat and power, CHP systems are thus becoming attractive due to the energy, economic, and environmental policies for pursuing stable electricity supply, sustainable development and environmental pollution mitigation in Taiwan. The objective of this paper is to present an updated analysis of CHP systems in Taiwan during the period from 1990 to 2010. The description in the paper is thus based on an analysis of electricity supply/consumption and its sources from CHP systems during the past two decades, and centered on two important regulations in compliance with CHP systems (i.e., Energy Management Law and Environmental Impact Assessment Act. Based on the total net power generation from CHP systems (i.e., 35,626 GWh in 2011, it was found that the carbon dioxide reduction benefits were estimated to be around 20,000 Gg.

  16. Development of a micro-cogeneration laboratory and testing of a natural gas CHP unit based on PEM fuel cells

    International Nuclear Information System (INIS)

    Campanari, S.; Valenti, G.; Macchi, E.; Lozza, G.; Ravidà, N.

    2014-01-01

    This work discusses the design and the development of a Laboratory of Micro-Cogeneration (LMC) at Politecnico di Milano. The LMC laboratory is a unique structure devoted to small-scale power generation, with the main goals of testing and improving the performance of systems that produce or utilize electric and thermal (hot and/or cold) power in a very general sense, spanning from combined heat and power (CHP) units to heaters, from absorption chillers to heat pumps, but also able to perform tests on fuel processors and electrolyzers. The laboratory features a supply of natural gas as well as H 2 and O 2 from a high pressure electrolyzer and of CO, CO 2 and N 2 from bottles, permitting to carry out experiments with simulated synthesis fuels. The maximum allowable electrical power produced, exported to the grid or to an electronic loadbank, or consumed by the system under test is 100 kW; maximum allowable thermal power is roughly 200 kW with variable temperature water circuits (from chilled water up to a 150 °C at 8 bar superheated water loop). This work outlines also the instruments used for on-line recording of thermodynamic properties, emissions and power, aiming at monitoring and reconstructing mass and energy balances. One of the first experimental campaign has been carried out on a CHP system based on polymer electrolyte membrane fuel cells (PEM), a promising candidate for distributed CHP thanks to low pollutant emissions and good efficiency, rapid startup and flexibility, although affected by a rather complex fuel processing section to provide the appropriate fuel to the PEM. This work presents the experimental analysis of a 20 kW prototype PEM CHP system complete of natural gas processor. The prototype is operated at LMC to characterize the processing section and the thermodynamic performances of the overall system. Despite its non-optimized layout, the unit has shown encouraging total efficiency (76%) and primary energy saving index (6%). - Highlights

  17. Energy efficiency analysis and impact evaluation of the application of thermoelectric power cycle to today's CHP systems

    DEFF Research Database (Denmark)

    Chen, Min; Lund, Henrik; Rosendahl, Lasse

    2010-01-01

    configurations for combustion systems. The feasible deployment of TEG in various CHP plants will be examined in terms of heat source temperature range, influences on CHP power specification and thermal environment, as well as potential benefits. The overall conversion efficiency improvements and economic...

  18. Total cost of ownership of CHP SOFC systems: Effect of installation context

    International Nuclear Information System (INIS)

    Arduino, Francesco; Santarelli, Massimo

    2016-01-01

    Solid oxide fuel cells (SOFC) are one of the most interesting between the emerging technologies for energy production. Although some information about the production cost of these devices are already known, their operational cost has not been studied yet with sufficient accuracy. This paper presents a life cycle cost (LCC) analysis of CHP (combined heat and power) SOFC systems performed in hospitals located in various cities of the US and one in Italy. In this study the strong effects of the installation context will be analyzed using a customized use phase model for each location. The cost effectiveness of these devices has been proved without credits in Mondovi (IT), New York (NY) and Minneapolis (MN) where the payback time goes from 10 to 7 years. Considering the credits, it is possible to obtain economic feasibility also in Chicago (IL) and reduce the payback for other cities to values from 4 to 6 years. In other cities like Phoenix (AZ) and Houston (TX) the payback can’t be reached in any case. The life cycle impact assessment analysis has shown how, even in the cities with cleaner electricity grid, there is a reduction in the emissions of both greenhouse gases and pollutants. - Highlights: •Life cycle cost analysis has been performed for CHP SOFC systems. •The strong effects of the installation context have been analyzed. •Economic feasibility has been proven in new york, Minneapolis and Mondovi. •Economic feasibility can’t be reached in phoenix and Houston. •SOFC always provide a reduction in the emissions of greenhouse gases and pollutant.

  19. Design of Biomass Combined Heat and Power (CHP Systems based on Economic Risk using Minimax Regret Criterion

    Directory of Open Access Journals (Sweden)

    Ling Wen Choong

    2018-01-01

    Full Text Available It is a great challenge to identify optimum technologies for CHP systems that utilise biomass and convert it into heat and power. In this respect, industry decision makers are lacking in confidence to invest in biomass CHP due to economic risk from varying energy demand. This research work presents a linear programming systematic framework to design biomass CHP system based on potential loss of profit due to varying energy demand. Minimax Regret Criterion (MRC approach was used to assess maximum regret between selections of the given biomass CHP design based on energy demand. Based on this, the model determined an optimal biomass CHP design with minimum regret in economic opportunity. As Feed-in Tariff (FiT rates affects the revenue of the CHP plant, sensitivity analysis was then performed on FiT rates on the selection of biomass CHP design. Besides, design analysis on the trend of the optimum design selected by model was conducted. To demonstrate the proposed framework in this research, a case study was solved using the proposed approach. The case study focused on designing a biomass CHP system for a palm oil mill (POM due to large energy potential of oil palm biomass in Malaysia.

  20. Innovative Hybrid CHP systems for high temperature heating plant in existing buildings

    NARCIS (Netherlands)

    de Santoli, Livio; Lo Basso, Gianluigi; Nastasi, B.; d’Ambrosio Alfano, Francesca R.; Mazzarella and Piercarlo, Livio

    2017-01-01

    This paper deals with the potential role of new hybrid CHP systems application providing both electricity and heat which are compatible with the building architectural and landscape limitations. In detail, three different plant layout options for high temperature heat production along with the

  1. Small scale CHP: Alternative integration forms in the Danish energy system

    International Nuclear Information System (INIS)

    Boeg, Rasmus; Gatautis, Ramunas; Engberg Pedersen, Thomas; Schmidt, Rune; Ravn, Hans F.

    2003-01-01

    In Denmark, introduction of small scale combined heat and power (CHP) plants were part of the energy policy during the 1990's. Thus, the installed electricity capacity on this type of units multiplied approximately ten times during this decade, to constitute more than 2000 MW in 2000, or around 20% of total installed electricity capacity. The motivation for this development was mainly energy savings due to the relatively high thermal efficiency in combined production, and the associated reduction of emissions. The remuneration for the electricity delivered to the electrical network was in part based on a feed in tariff. The construction of the tariff reflected estimated benefits to the electrical system. With the liberalisation of the electricity markets this arrangement has been questioned, and it has been suggested that the differentiated payment to local CHP should be based on electricity market prising. For Denmark this would imply that the local CHP should trade the electricity on the Nordpool electricity spot market. This paper analyses parts of these two alternative ways of economic arrangements in relation to small scale CHP. First it describes the development and status till now. Then it analyses the production patterns and associated economic consequences of a change from the tariff based system to a market system. (BA)

  2. Optimization of a High Temperature PEMFC micro-CHP System by Formulation and Application of a Process Integration Methodology

    DEFF Research Database (Denmark)

    Arsalis, Alexandros; Nielsen, Mads Pagh; Kær, Søren Knudsen

    2013-01-01

    A 1 kWe micro combined heat and power (CHP) system based on high temperature proton exchange membrane fuel cell (PEMFC) technology is modeled and optimized by formulation and application of a process integration methodology. The system can provide heat and electricity for a singlefamily household......, the heat exchange network (HEN) annual cost is minimized. The results show the high potential of the proposed model since high efficiencies are accomplished. The net electrical efficiency and total system efficiency, based on lower heating value (LHV), are 35.2% and 91.1%, respectively. The minimized total...... annual cost of the HEN is $8,147 year–1....

  3. Evaluation of Combined Heat and Power (CHP Systems Using Fuzzy Shannon Entropy and Fuzzy TOPSIS

    Directory of Open Access Journals (Sweden)

    Fausto Cavallaro

    2016-06-01

    Full Text Available Combined heat and power (CHP or cogeneration can play a strategic role in addressing environmental issues and climate change. CHP systems require less fuel than separate heat and power systems in order to produce the same amount of energy saving primary energy, improving the security of the supply. Because less fuel is combusted, greenhouse gas emissions and other air pollutants are reduced. If we are to consider the CHP system as “sustainable”, we must include in its assessment not only energetic performance but also environmental and economic aspects, presenting a multicriteria issue. The purpose of the paper is to apply a fuzzy multicriteria methodology to the assessment of five CHP commercial technologies. Specifically, the combination of the fuzzy Shannon’s entropy and the fuzzy Technique for Order of Preference by Similarity to Ideal Solution (TOPSIS approach will be tested for this purpose. Shannon’s entropy concept, using interval data such as the α-cut, is a particularly suitable technique for assigning weights to criteria—it does not require a decision-making (DM to assign a weight to the criteria. To rank the proposed alternatives, a fuzzy TOPSIS method has been applied. It is based on the principle that the chosen alternative should be as close as possible to the positive ideal solution and be as far as possible from the negative ideal solution. The proposed approach provides a useful technical–scientific decision-making tool that can effectively support, in a consistent and transparent way, the assessment of various CHP technologies from a sustainable point of view.

  4. Dedicated Work Opportunities of Municipal CHP Blocks in a Catastrophic Failure of the Power System State

    Directory of Open Access Journals (Sweden)

    Ireneusz Grządzielski

    2014-04-01

    Full Text Available Under conditions of a catastrophic system failure developing, in the Polish Power System (PPS, the creation of island systems powered by municipal CHP generating units may be one way to maintain the units’ production capacity. Block island load system BC 50 could create own and general EC Karolin and industrial plants located in the immediate vicinity of the thermal-electric power station receipts.

  5. Modeling and off-design performance of a 1 kWe HT-PEMFC (high temperature-proton exchange membrane fuel cell)-based residential micro-CHP (combined-heat-and-power) system for Danish single-family households

    DEFF Research Database (Denmark)

    Arsalis, Alexandros; Nielsen, Mads Pagh; Kær, Søren Knudsen

    2011-01-01

    temperatures, as compared to Nafion-based PEMFCs and therefore can be a significant candidate for cogeneration residential systems. The proposed system can provide electric power, hot water, and space heating for a typical Danish single-family household. A complete fuel processing subsystem, with all necessary......A novel proposal for the modeling and operation of a micro-CHP (combined-heat-and-power) residential system based on HT-PEMFC (High Temperature-Proton Exchange Membrane Fuel Cell) technology is described and analyzed to investigate its commercialization prospects. An HT-PEMFC operates at elevated...

  6. Research, Development and Demonstration of Micro-CHP System for Residential Applications

    Energy Technology Data Exchange (ETDEWEB)

    Karl Mayer

    2010-03-31

    ECR International and its joint venture company, Climate Energy, are at the forefront of the effort to deliver residential-scale combined heat and power (Micro-CHP) products to the USA market. Part of this substantial program is focused on the development of a new class of steam expanders that offers the potential for significantly lower costs for small-scale power generation technology. The heart of this technology is the scroll expander, a machine that has revolutionized the HVAC refrigerant compressor industry in the last 15 years. The liquid injected cogeneration (LIC) technology is at the core of the efforts described in this report, and remains an excellent option for low cost Micro-CHP systems. ECR has demonstrated in several prototype appliances that the concept for LIC can be made into a practical product. The continuing challenge is to identify economical scroll machine designs that will meet the performance and endurance requirements needed for a long life appliance application. This report describes the numerous advances made in this endeavor by ECR International. Several important advances are described in this report. Section 4 describes a marketing and economics study that integrates the technical performance of the LIC system with real-world climatic data and economic analysis to assess the practical impact that different factors have on the economic application of Micro-CHP in residential applications. Advances in the development of a working scroll steam expander are discussed in Section 5. A rigorous analytical assessment of the performance of scroll expanders, including the difficult to characterize impact of pocket to pocket flank leakage, is presented in Section 5.1. This is followed with an FEA study of the thermal and pressure induced deflections that would result from the normal operation of an advanced scroll expander. Section 6 describes the different scroll expanders and test fixtures developed during this effort. Another key technical

  7. Conceptual study of a 250 kW planar SOFC system for CHP application

    Science.gov (United States)

    Fontell, E.; Kivisaari, T.; Christiansen, N.; Hansen, J.-B.; Pålsson, J.

    In August 2002, Wärtsilä Corporation and Haldor Topsøe A/S entered into a co-operation agreement to start joint development program within the planar SOFC technology. The development program aims to bring to the market highly efficient, clean and cost competitive fuel cell systems with power outputs above 200 kW for distributed power generation with CHP and for marine applications. In this study, the product concept for a 250 kW natural gas-fuelled atmospheric SOFC plant has been studied. The process has been calculated and optimised for high electrical efficiency. In the calculations, system efficiencies more than 55-85% (electrical co-generation) have been reached. The necessary balance of plant (BoP) components have been identified and the concept for grid connection has been defined. The BoP includes fuel and air supply, anode re-circulation, start-up steam, purge gas, exhaust gas heat recovery, back-up power, power electronics and control system. Based on the analysed system and component information, a conceptual design and cost break down structure for the product have been made. The cost breakdown shows that the stack, system control and power electronics are the major cost factors, while the remaining BoP equipment stands for a minor share of the manufacturing cost. Finally, the feasibility of the SOFC plants has been compared to gas engines.

  8. Development of Next Generation micro-CHP System

    DEFF Research Database (Denmark)

    Arsalis, Alexandros

    provide electricity, hot water, and space heating for an average single-family household in Denmark. A complete fuel processing subsystem, with all necessary BOP (balance-of-plant) components, is modeled and coupled to the fuel cell stack subsystem. The research project is divided into five main study...... topics: (a) Modeling, simulation and validation of the system in LabVIEW environment to provide the ability of Data Acquisition of actual components, and thereby more realistic design in the future; (b) Modeling, parametric study, and sensitivity analysis of the system in EES (Engineering Equation Solver......). The parametric study is conducted to determine the most viable system/component design based on maximizing total system efficiency; (c) An improved operational strategy is formulated and applied in an attempt to minimize operational implications, experienced when using conventional operational strategies; (d...

  9. Modeling of non-linear CHP efficiency curves in distributed energy systems

    DEFF Research Database (Denmark)

    Milan, Christian; Stadler, Michael; Cardoso, Gonçalo

    2015-01-01

    Distributed energy resources gain an increased importance in commercial and industrial building design. Combined heat and power (CHP) units are considered as one of the key technologies for cost and emission reduction in buildings. In order to make optimal decisions on investment and operation...... for these technologies, detailed system models are needed. These models are often formulated as linear programming problems to keep computational costs and complexity in a reasonable range. However, CHP systems involve variations of the efficiency for large nameplate capacity ranges and in case of part load operation......, which can be even of non-linear nature. Since considering these characteristics would turn the models into non-linear problems, in most cases only constant efficiencies are assumed. This paper proposes possible solutions to address this issue. For a mixed integer linear programming problem two...

  10. The Pseudomonas aeruginosa Chp Chemosensory System Regulates Intracellular cAMP Levels by Modulating Adenylate Cyclase Activity

    Science.gov (United States)

    Fulcher, Nanette B.; Holliday, Phillip M.; Klem, Erich; Cann, Martin J.; Wolfgang, Matthew C.

    2010-01-01

    Summary Multiple virulence systems in the opportunistic pathogen Pseudomonas aeruginosa are regulated by the second messenger signaling molecule adenosine 3’, 5’-cyclic monophosphate (cAMP). Production of cAMP by the putative adenylate cyclase enzyme CyaB represents a critical control point for virulence gene regulation. To identify regulators of CyaB, we screened a transposon insertion library for mutants with reduced intracellular cAMP. The majority of insertions resulting in reduced cAMP mapped to the Chp gene cluster encoding a putative chemotaxis-like chemosensory system. Further genetic analysis of the Chp system revealed that it has both positive and negative effects on intracellular cAMP and that it regulates cAMP levels by modulating CyaB activity. The Chp system was previously implicated in the production and function of type IV pili (TFP). Given that cAMP and the cAMP-dependent transcriptional regulator Vfr control TFP biogenesis gene expression, we explored the relationship between cAMP, the Chp system and TFP regulation. We discovered that the Chp system controls TFP production through modulation of cAMP while control of TFP-dependent twitching motility is cAMP-independent. Overall, our data define a novel function for a chemotaxis-like system in controlling cAMP production and establish a regulatory link between the Chp system, TFP and other cAMP-dependent virulence systems. PMID:20345659

  11. Environmental sustainability analysis of UK whole-wheat bioethanol and CHP systems

    International Nuclear Information System (INIS)

    Martinez-Hernandez, Elias; Ibrahim, Muhammad H.; Leach, Matthew; Sinclair, Phillip; Campbell, Grant M.; Sadhukhan, Jhuma

    2013-01-01

    The UK whole-wheat bioethanol and straw and DDGS-based combined heat and power (CHP) generation systems were assessed for environmental sustainability using a range of impact categories or characterisations (IC): cumulative primary fossil energy (CPE), land use, life cycle global warming potential over 100 years (GWP 100 ), acidification potential (AP), eutrophication potential (EP) and abiotic resources use (ARU). The European Union (EU) Renewable Energy Directive's target of greenhouse gas (GHG) emission saving of 60% in comparison to an equivalent fossil-based system by 2020 seems to be very challenging for stand-alone wheat bioethanol system. However, the whole-wheat integrated system, wherein the CHP from the excess straw grown in the same season and from the same land is utilised in the wheat bioethanol plant, can be demonstrated for potential sustainability improvement, achieving 85% emission reduction and 97% CPE saving compared to reference fossil systems. The net bioenergy from this system and from 172,370 ha of grade 3 land is 12.1 PJ y −1 providing land to energy yield of 70 GJ ha −1 y −1 . The use of DDGS as an animal feed replacing soy meal incurs environmental emission credit, whilst its use in heat or CHP generation saves CPE. The hot spots in whole system identified under each impact category are as follows: bioethanol plant and wheat cultivation for CPE (50% and 48%), as well as for ARU (46% and 52%). EP and GWP 100 are distributed among wheat cultivation (49% and 37%), CHP plant (26% and 30%) and bioethanol plant (25%, and 33%), respectively. -- Highlights: ► UK whole-wheat energy system can achieve 85% GHG emission reduction. ► UK whole-wheat energy system can achieve 97% primary energy saving. ► The land to energy yield of the UK whole-wheat system is 70 GJ ha −1 y −1 . ► Fertiliser production is the hotspot. ► DDGS and straw-based CHP system integration to wheat bioethanol is feasible

  12. Biomass CHP Catalog of Technologies

    Science.gov (United States)

    This report reviews the technical and economic characterization of biomass resources, biomass preparation, energy conversion technologies, power production systems, and complete integrated CHP systems.

  13. Hypoxia promotes etoposide (VP-16) resistance in neuroblastoma CHP126 cells.

    Science.gov (United States)

    Wang, Duoduo; Zhu, Qionghua; Zhang, Xiayan; Zhang, Lei; He, Qiaojun; Yang, Bo

    2010-01-01

    Hypoxia is widespread in solid tumors as a consequence of poorly structured tumor-derived neovasculature, which is recognized to play a role in the resistance of cancer cells to chemotherapy. Etoposide (VP-16), a drug commonly used in chemotherapy, leads to enhanced accumulation of cell populations in G2/M phase and increases levels of apoptosis as a topoisomerase II inhibitor. We evaluated the effects of hypoxia on the response of the neuroblastoma cell line CHP126 to VP-16, in order to delineate the mechanisms responsible for the hypoxia-induced chemoresistance of this clinically conventional anti-cancer agent, with an insight to determining potential indications in neuroblastoma therapy. In this study, physiological hypoxia was shown to attenuate G2/M arrest and apoptosis induced in CHP126 cells by VP-16. It suppressed drug-related Cdk1 activity with a less elevation of regulator proteins such as cyclin B1, Cdk7 and reduced caspase activation and PARP cleavage compared to the efficiency observed in normoxic condition, which were significantly relative with hypoxia-driven inhibition of p53 and p-ERK1/2 activation. These results clearly demonstrated that hypoxia had a protective effect against VP-16-induced cytotoxicity, which is likely to provide a further therapeutic knowledge in neuroblastomas.

  14. A Study of a Diesel Engine Based Micro-CHP System

    Energy Technology Data Exchange (ETDEWEB)

    Krishna, C.R.; Andrews, J.; Tutu, N.; Butcher, T.

    2010-08-31

    This project, funded by New York State Energy Research and Development Agency (NYSERDA), investigated the potential for an oil-fired combined heat and power system (micro-CHP system) for potential use in residences that use oil to heat their homes. Obviously, this requires the power source to be one that uses heating oil (diesel). The work consisted of an experimental study using a diesel engine and an analytical study that examined potential energy savings and benefits of micro-CHP systems for 'typical' locations in New York State. A search for a small diesel engine disclosed that no such engines were manufactured in the U.S. A single cylinder engine manufactured in Germany driving an electric generator was purchased for the experimental work. The engine was tested using on-road diesel fuel (15 ppm sulfur), and biodiesel blends. One of the main objectives was to demonstrate the possibility of operation in the so-called HCCI (Homogeneous Charge Compression Ignition) mode. The HCCI mode of operation of engines is being explored as a way to reduce the emission of smoke, and NOx significantly without exhaust treatment. This is being done primarily in the context of engines used in transportation applications. However, it is felt that in a micro-CHP application using a single cylinder engine, such an approach would confer those emission benefits and would be much easier to implement. This was demonstrated successfully by injecting the fuel into the engine air intake using a heated atomizer made by Econox Technologies LLC to promote significant vaporization before entering the cylinder. Efficiency and emission measurements were made under different electrical loads provided by two space heaters connected to the generator in normal and HCCI modes of operation. The goals of the analytical work were to characterize, from the published literature, the prime-movers for micro-CHP applications, quantify parametrically the expected energy savings of using micro-CHP

  15. A Spreadsheet Algorithm for Determining the Economic Feasibility of Micro-CHP Systems in the Arkansas Manufacturing Sector

    Science.gov (United States)

    Lewallen, Ford

    Combined heat and power (CHP) systems are not new to the market. However, advances in technology, specifically MicroTurbines, have presented new opportunities for installations of micro-CHP units - defined as 50 kWe to 300 kWe, specifically at small- to medium-sized industrial facilities. One pressing concern is whether or not an industrial plant has a high enough process thermal load requirement to fully utilize the energy output. This thesis will discuss simulations that were run on several actual electric and thermal load combinations, which correspond to types of manufacturing facilities commonly found in Arkansas. Analysis of the plant usage profiles will identify economically feasible scenarios from CHP production based on electric and thermal loads, electric demand and energy costs, the cost of natural gas, and CHP unit size and efficiencies. The spreadsheet algorithm will be written in a form to allow a user to select utility rate structures from major utility companies in Arkansas, or customize their own rate schedule, and enter their monthly energy usages and demands. The user can then compare and contrast costs and savings of different CHP units, and then make informed decisions on whether a company would benefit from installing a CHP system.

  16. Trial operation of a phosphoric acid fuel cell (PC25) for CHP applications in Europe

    Energy Technology Data Exchange (ETDEWEB)

    Uhrig, M.; Droste, W.; Wolf, D. [Ruhrgas AG, Dorsten (Germany)

    1996-12-31

    In Europe, ten 200 kW phosphoric acid fuel cells (PAFCs) produced by ONSI (PC25) are currently in operation. Their operators collaborate closely in the European Fuel Cell Users Group (EFCUG). The experience gained from trial operation by the four German operators - HEAG, HGW/HEW, Thyssengas and Ruhrgas - coincides with that of the other European operators. This experience can generally be regarded as favourable. With a view to using fuel cells in combined heat and power generation (CHP), the project described in this report, which was carried out in cooperation with the municipal utility of Bochum and Gasunie of the Netherlands, aimed at gaining experience with the PC 25 in field operation under the specific operating conditions prevailing in Europe. The work packages included heat-controlled operation, examination of plant behavior with varying gas properties and measurement of emissions under dynamic load conditions. The project received EU funding under the JOULE programme.

  17. CHP Project Development

    Science.gov (United States)

    Access information and tools to support the CHP project development process, including identifying if your facility is a good fit for CHP, the steps involved with CHP project development, and policies and incentives supportive of CHP.

  18. DEVELOPMENT OF THE CHP-THERMAL SCHEMES IN CONTEXTS OF THE CONSOLIDATED ENERGY SYSTEM OF BELARUS

    Directory of Open Access Journals (Sweden)

    V. N. Romaniuk

    2015-01-01

    Full Text Available The paper deals with the structural specifics of the Belarus Consolidated Energy System capacities in view of their ongoing transfer to the combined-cycle technology, building the nuclear power plant and necessity for the generating capacity regulation in compliance with the load diagram. With the country’s economic complex energy utilization pattern being preserved, the generating capacities are subject to restructuring and the CHP characteristics undergo enhancement inter alia a well-known increase of the specific electricity production based on the heat consumption. Because of this the steam-turbine condensation units which are the traditional capacity regulators for the energy systems with heat power plants dominance are being pushed out of operation. In consequence of this complex of changes the issue of load diagram provision gains momentum which in evidence is relevant to the Consolidated Energy System of Belarus. One of the ways to alleviate acuteness of the problem could be the specific electric energy production cut on the CHP heat consumption with preserving the heat loads and without their handover to the heat generating capacities of direct combustion i.e. without fuel over-burning. The solution lies in integrating the absorption bromous-lithium heat pump units into the CHP thermal scheme. Through their agency low-temperature heat streams of the generator cooling, the lubrication and condensation heat-extraction of steam minimal passing to the condenser systems are utilized. As a case study the authors choose one of the CHPs in the conditions of which the corresponding employment of the said pumps leads to diminution of the fuel-equivalent specific flow-rate by 20−25 g for 1 kW⋅h production and conjoined electric energy generation capacity lowering. The latter will be handed over to other generating capacities, and the choice of them affects economic expediency of the absorption bromous-lithium heat pump-units installation

  19. CHP Energy and Emissions Savings Calculator

    Science.gov (United States)

    Download the CHP Emissions Calculator, a tool that calculates the difference between the anticipated carbon dioxide, methane, nitrous oxide, sulfur dioxide, and nitrogen oxide emissions from a CHP system to those of a separate heat and power system.

  20. Thermal gain of CHP steam generator plants and heat supply systems

    Science.gov (United States)

    Ziganshina, S. K.; Kudinov, A. A.

    2016-08-01

    Heating calculation of the surface condensate heat recovery unit (HRU) installed behind the BKZ-420-140 NGM boiler resulting in determination of HRU heat output according to fire gas value parameters at the heat recovery unit inlet and its outlet, heated water quantity, combustion efficiency per boiler as a result of installation of HRU, and steam condensate discharge from combustion products at its cooling below condensing point and HRU heat exchange area has been performed. Inspection results of Samara CHP BKZ-420-140 NGM power boilers and field tests of the surface condensate heat recovery unit (HRU) made on the bimetal calorifier base KCk-4-11 (KSk-4-11) installed behind station no. 2 Ulyanovsk CHP-3 DE-10-14 GM boiler were the basis of calculation. Integration of the surface condensation heat recovery unit behind a steam boiler rendered it possible to increase combustion efficiency and simultaneously decrease nitrogen oxide content in exit gases. Influence of the blowing air moisture content, the excess-air coefficient in exit gases, and exit gases temperature at the HRU outlet on steam condensate amount discharge from combustion products at its cooling below condensing point has been analyzed. The steam condensate from HRU gases is offered as heat system make-up water after degasification. The cost-effectiveness analysis of HRU installation behind the Samara CHP BKZ-420-140 NGM steam boiler with consideration of heat energy and chemically purified water economy has been performed. Calculation data for boilers with different heat output has been generalized.

  1. Research, Development and Demonstration of Micro-CHP Systems for Residential Applications - Phase I

    Energy Technology Data Exchange (ETDEWEB)

    Robert A. Zogg

    2011-03-14

    The objective of the Micro-CHP Phase I effort was to develop a conceptual design for a Micro-CHP system including: Defining market potential; Assessing proposed technology; Developing a proof-of-principle design; and Developing a commercialization strategy. TIAX LLC assembled a team to develop a Micro-CHP system that will provide electricity and heating. TIAX, the contractor and major cost-share provider, provided proven expertise in project management, prime-mover design and development, appliance development and commercialization, analysis of residential energy loads, technology assessment, and market analysis. Kohler Company, the manufacturing partner, is a highly regarded manufacturer of standby power systems and other residential products. Kohler provides a compellingly strong brand, along with the capabilities in product development, design, manufacture, distribution, sales, support, service, and marketing that only a manufacturer of Kohler's status can provide. GAMA, an association of appliance and equipment manufacturers, provided a critical understanding of appliance commercialization issues, including regulatory requirements, large-scale market acceptance issues, and commercialization strategies. The Propane Education & Research Council, a cost-share partner, provided cost share and aided in ensuring the fuel flexibility of the conceptual design. Micro-CHP systems being commercialized in Europe and Japan are generally designed to follow the household thermal load, and generate electricity opportunistically. In many cases, any excess electricity can be sold back to the grid (net metering). These products, however, are unlikely to meet the demands of the U.S. market. First, these products generally cannot provide emergency power when grid power is lost--a critical feature to market success in the U.S. Even those that can may have insufficient electric generation capacities to meet emergency needs for many U.S. homes. Second, the extent to which net

  2. Economic potentials of CHP connected to district heat systems in Germany. Implementation of the EU Efficiency Directive

    International Nuclear Information System (INIS)

    Eikmeier, Bernd

    2015-01-01

    The EU Efficiency Directive (2012/27/EU) is requiring all member states to carry out an evaluation of the potential for highly efficient CHP and the efficient use of district heating and cooling by December 2015. The German Federal Ministry of Economic Affairs and Energy appointed this task to the Fraunhofer Institute for Manufacturing and Advanced Materials, division for Energy Systems Analysis (formerly Bremer Energie Institut) in conjunction with other partners. The results for the sector district- and communal heating with CHP, sub-sectors private households, trade and services industry, are presented in this article.

  3. Australian coal mine methane emissions mitigation potential using a Stirling engine-based CHP system

    International Nuclear Information System (INIS)

    Meybodi, Mehdi Aghaei; Behnia, Masud

    2013-01-01

    Methane, a major contributor to global warming, is a greenhouse gas emitted from coal mines. Abundance of coal mines and consequently a considerable amount of methane emission requires drastic measures to mitigate harmful effects of coal mining on the environment. One of the commonly adopted methods is to use emitted methane to fuel power generation systems; however, instability of fuel sources hinders the development of systems using conventional prime movers. To address this, application of Stirling engines may be considered. Here, we develop a techno-economic methodology for conducting an optimisation-based feasibility study on the application of Stirling engines as the prime movers of coal mine CHP systems from an economic and an environmental point of view. To examine the impact of environmental policies on the economics of the system, the two commonly implemented ones (i.e. a carbon tax and emissions trading scheme) are considered. The methodology was applied to a local coal mine. The results indicate that incorporating the modelled system not only leads to a substantial reduction in greenhouse gas emissions, but also to improved economics. Further, due to the heavy economic burden, the carbon tax scheme creates great incentive for coal mine industry to address the methane emissions. -- Highlights: •We study the application of Stirling engines in coal mine CHP systems. •We develop a thermo-economic approach based on the net present worth analysis. •We examine the impact of a carbon tax and ETS on the economics of the system. •The modeled system leads to a substantial reduction in greenhouse gas emissions. •Carbon tax provides a greater incentive to address the methane emissions

  4. Analysis of the impact of Heat-to-Power Ratio for a SOFC-based mCHP system for residential application under different climate regions in Europe

    DEFF Research Database (Denmark)

    Liso, Vincenzo; Zhao, Yingru; Brandon, Nigel

    2011-01-01

    according to the summer energy demand. The winter energy demand shows a Heat-to-Power Ratio which cannot be covered by the mCHP unit alone. To ensure that the mCHP system meets both the thermal and electrical energy demand over the entire year, an auxiliary boiler and a hot water storage tank need...

  5. Experience of Implementing a Distributed Control System for Thermal and Mechanical and Electrical Equipment at the South-West CHP

    Energy Technology Data Exchange (ETDEWEB)

    Babkin, K. V., E-mail: babkin@uztec.ru; Tsvetkov, M. S.; Kostyuk, R. I.; Chugin, A. V. [SC “South-West CHP” (Russian Federation); Bilenko, V. A.; Molchanov, K. A.; Fedunov, V. V. [JSC “Interautomatika” (Russian Federation)

    2015-01-15

    Results of implementing an SPPA-T3000-based unified distributed control system for thermal and mechanical and electrical equipment at the South-West CHP are discussed. Hardware solutions for integration with local control systems, control of electrical equipment in compliance with the standards IEC 61850, Modbus RTU, and communication between the plant control system and the System Operator of the Unified Power System are described.

  6. Elimination of restraints on the propagation of combined heat and power (CHP) generation systems in Switzerland

    International Nuclear Information System (INIS)

    Rieder, S.; Landis, F.; Lienhard, A.; Marti Locher, F.; Krummenacher, S.

    2009-04-01

    This report for the Swiss Federal Office of Energy (SFOE) discusses the results of study initiated by the SFOE that was to investigate the reasons for the low level of proliferation of CHP technology in Switzerland. The two main questions asked - which factors inhibit the use of CHP in particular application areas and which energy-policy measures can remove such obstacles - are discussed. The use of CHP in various areas of application from waste incineration plants through to units used in residential buildings is analysed and commented on. Recommendations on measures that can be taken to enhance the use of CHP are discussed. Three strategy variants available to the public services area are presented and discussed. It is noted that a consensus between players in the technical and political areas is necessary

  7. WORKING PARK-FUEL CELL COMBINED HEAT AND POWER SYSTEM

    Energy Technology Data Exchange (ETDEWEB)

    Allan Jones

    2003-09-01

    This report covers the aims and objectives of the project which was to design, install and operate a fuel cell combined heat and power (CHP) system in Woking Park, the first fuel cell CHP system in the United Kingdom. The report also covers the benefits that were expected to accrue from the work in an understanding of the full technology procurement process (including planning, design, installation, operation and maintenance), the economic and environmental performance in comparison with both conventional UK fuel supply and conventional CHP and the commercial viability of fuel cell CHP energy supply in the new deregulated energy markets.

  8. Preliminary experimental investigation of a natural gas-fired ORC-based micro-CHP system for residential buildings

    International Nuclear Information System (INIS)

    Farrokhi, M.; Noie, S.H.; Akbarzadeh, A.A.

    2014-01-01

    The continual increases in energy demand and greenhouse gas emissions, call for efficient use of energy resources. Decentralized combined heat and power (CHP) technology provides an alternative for the world to meet and solve energy-related problems including energy shortages, energy supply security, emission control and conservation of energy. This paper presents the preliminary results of an experimental investigation of a natural gas-fired micro-CHP system for residential buildings based on an organic Rankine cycle (ORC). Isopentane was used as the ORC working fluid in consideration of several criteria including its environmentally-friendly characteristics. Experiments were conducted to evaluate the performance of the developed system at different heat source temperatures of nominally 85, 80, 75, 70, and 65 °C. The maximum electrical power output of 77.4 W was generated at heating water entry temperature of 84.1 °C, corresponding to net cycle electrical efficiency of 1.66%. Further work will be done with a view to increasing the cycle electrical efficiency by using more efficient components, in particular the expander and generator. - Highlights: •A natural gas-fired ORC-based micro-scale CHP system has been developed and tested. •The good agreement between the mechanical and gross power validates the assumptions. •A vane expander suits a micro-CHP system based on an organic Rankine cycle. •A vane expander does not suit power generation by a Trilateral Flash Cycle (TFC). •Domestic gas-fired ORC systems may reduce reliance on central power stations

  9. Energy Analysis and Multi-Objective Optimization of an Internal Combustion Engine-Based CHP System for Heat Recovery

    Directory of Open Access Journals (Sweden)

    Abdolsaeid Ganjehkaviri

    2014-10-01

    Full Text Available A comprehensive thermodynamic study is conducted of a diesel based Combined Heat and Power (CHP system, based on a diesel engine and an Organic Rankine Cycle (ORC. Present research covers both energy and exergy analyses along with a multi-objective optimization. In order to determine the irreversibilities in each component of the CHP system and assess the system performance, a complete parametric study is performed to investigate the effects of major design parameters and operating conditions on the system’s performance. The main contribution of the current research study is to conduct both exergy and multi-objective optimization of a system using different working fluid for low-grade heat recovery. In order to conduct the evolutionary based optimization, two objective functions are considered in the optimization; namely the system exergy efficiency, and the total cost rate of the system, which is a combination of the cost associated with environmental impact and the purchase cost of each component. Therefore, in the optimization approach, the overall cycle exergy efficiency is maximized satisfying several constraints while the total cost rate of the system is minimized. To provide a better understanding of the system under study, the Pareto frontier is shown for multi-objective optimization and also an equation is derived to fit the optimized point. In addition, a closed form relationship between exergy efficiency and total cost rate is derived.

  10. Thermodynamic analysis of a novel multigeneration energy system based on heat recovery from a biomass CHP cycle

    International Nuclear Information System (INIS)

    Soltani, Reza; Dincer, Ibrahim; Rosen, Marc A.

    2015-01-01

    A multigeneration energy system with one fuel intake (sawdust biomass fuel) and five useful outputs is proposed and energy and exergy analyses are carried out to assess its performance. Instead of using a simple heat exchanger to satisfy district heating needs, applying a deaerator is found to result in 10% more hot water mass flow rate for the same conditions. The energy and exergy efficiencies of the multigeneration system are found to be around 60% and 25%, respectively, while the corresponding energy and exergy efficiencies of a biomass system with only electricity generation are 11% and 13%, respectively. When investigating the effect of adding various product outputs to biomass power generation, steam generation and then domestic hot water production are found to have the greatest enhancing effects on the system efficiencies. Heat recovery from exhaust gases for district heating and wood drying is found to enhance the energy efficiency more than the exergy efficiency. Also, due to the size of the heat recovery system, which is smaller than the biomass CHP cycle, district heating and drying cannot increase the energy and exergy efficiencies of the primary system like steam generation. A parametric study shows that the biomass fuel input rate affects significantly the district heating heat load and the electricity generation rate, in a linear manner. However, increasing the biomass input rate has no effect on the CHP system energy and exergy efficiencies, while increasing the exergy efficiency of the entire system and decreasing its corresponding energy efficiency slightly. Of the several heat recovery options from exhaust gases, electricity generation and wood drying result in the highest exergy efficiency while district heating and drying lead to highest energy efficiency. - Highlights: • Novel heat recovery based energy system is proposed. • There is one energy input while system has 5 useful outputs. • Combustion excess air increases district heating

  11. Development and test of a Stirling engine driven by waste gases for the micro-CHP system

    International Nuclear Information System (INIS)

    Li Tie; Tang Dawei; Li Zhigang; Du Jinglong; Zhou Tian; Jia Yu

    2012-01-01

    In recent years, micro-CHP systems are attracting world attention. As one kind of external heating engines, Stirling engines could be applied to the micro-CHP systems driven by solar, biogas, mid-high temperature waste gases and many other heat sources. The development of a Stirling engine driven by mid-high temperature waste gases is presented first. The thermodynamic design method, the key parameters of the designed Stirling engine and its combustion chamber adapted for waste gases are described in detail. Then the performance test of the Stirling engine is carried out. During the test, the temperature of the heater head is monitored by thermocouples, and the pressure of the working fluid helium in the Stirling engine is monitored by pressure sensors. The relationships among the output shaft power, torque and speed are studied, and the pressure losses of the working fluid in the heat exchanger system are also analyzed. The test results demonstrate that the output shaft power could reach 3476 W at 1248 RPM, which is in good agreement with the predicted value of 3901 W at 1500 RPM. The test results confirm the fact that Stirling engines driven by mid-high temperature waste gases are able to achieve a valuable output power for engineering application. - Highlights: ► A β-type Stirling engine whose output power could reach about 3.5 kW is developed by ourselves. ► Waste gases are used as the heat source to drive the Stirling engine. ► Test on the relationship among the power, torque, and speed are presented. ► The pressure changing process of the working fluid in the heat exchanger system during the test is recorded and analyzed.

  12. Performance comparison between partial oxidation and methane steam for SOFC micro-CHP systems

    DEFF Research Database (Denmark)

    Liso, Vincenzo; Olesen, Anders Christian; Nielsen, Mads Pagh

    2011-01-01

    The aim of this research work is to describe in qualitative and quantitative form the performance of a micro Combined Heat and Power system for residential application based on Solid Oxide Fuel Cell fueled by natural gas with two different types of pre-reforming systems, namely Steam Reforming...... and Partial Oxidation and recirculation of anode and cathode gas. The comparative analysis among the different configurations will lead us to conclude that maximum efficiency is achieved when cathode and anode gas recirculation are used along with steam methane reforming. Further Steam Methane Reforming...... process produces a higher electrical system efficiency compared to Partial oxidation reforming process. Efficiency is affected when running the system in part load mode mainly due to heat loss, additional natural gas supplied to the burner to satisfy the required heat demand inside the system, and ejector...

  13. Molten carbonate fuel cells to improve the perfomance of CHP in wastewater treatment facilities

    OpenAIRE

    Sánchez Martínez, David Tomás; Monje Brenes, Benjamín; Chacartegui, R.; Campanari, S.; Sánchez Lencero, Tomás Manuel

    2011-01-01

    The concern about environmental sustainability brought about by global warming in the last decades along with the scarcity of fossil fuel resources has fostered the research in renewable energies, high efficiency power generation systems and carbon dioxide capture and storage opportunities. The present work shows the performance of a system closely related to these three research areas. It focuses on a hybrid system composed by a reciprocating engine set (ICE) fuelled with biogas (BG) and a ...

  14. Energetic and Exergetic Analysis of a Heat Exchanger Integrated in a Solid Biomass-Fuelled Micro-CHP System with an Ericsson Engine

    Directory of Open Access Journals (Sweden)

    Marie Creyx

    2016-04-01

    Full Text Available A specific heat exchanger has been developed to transfer heat from flue gas to the working fluid (hot air of the Ericsson engine of a solid biomass-fuelled micro combined heat and power (CHP. In this paper, the theoretical and experimental energetic analyses of this heat exchanger are compared. The experimental performances are described considering energetic and exergetic parameters, in particular the effectiveness on both hot and cold sides. A new exergetic parameter called the exergetic effectiveness is introduced, which allows a comparison between the real and the ideal heat exchanger considering the Second Law of Thermodynamics. A global analysis of exergetic fluxes in the whole micro-CHP system is presented, showing the repartition of the exergy destruction among the components.

  15. Clinical Implications of CD4+CD25+Foxp3+Regulatory T Cell Frequencies After CHP-MAGE-A4 Cancer Vaccination.

    Science.gov (United States)

    Wada, Masataka; Tsuchikawa, Takahiro; Kyogoku, Noriaki; Abiko, Takehiro; Miyauchi, Kengo; Takeuchi, Shintaro; Kuwatani, Toshihiko; Shichinohe, Toshiaki; Miyahara, Yoshihiro; Kageyama, Shinichi; Ikeda, Hiroaki; Shiku, Hiroshi; Hirano, Satoshi

    2018-03-01

    The aim of this study was to explore whether the treatment effect or immune response to a cancer vaccine can be predicted by the percentage of CD4 + CD25 + Foxp3 + regulatory T cells (Tregs) in peripheral blood mononuclear cells (PBMCs) after vaccination. Sixteen patients (9 men, 7 women; median age 61.5 years) enrolled in the CHP-MAGE-A4 cancer vaccine clinical trial who had a fixed dose (300 μg of CHP-MAGE-A4 cancer vaccine and 0.5 Klinische Einheit (KE) of OK432 and received at least four vaccinations were investigated. Safety, immune response, and clinical effects were assessed before and after the cancer vaccination. Treg ratios that remained low both before and after vaccination were associated with a good prognosis, and a low Treg/CD4 lymphocyte ratio 7-weeks after the initial vaccination was correlated with a better prognosis. The Treg ratio following vaccination appears to have some utility for predicting patient prognosis. Copyright© 2018, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

  16. Demonstration of Next-Generation PEM CHP Systems for Global Markets Using PBI Membrane Technology

    Energy Technology Data Exchange (ETDEWEB)

    Vogel, John [Plug Power Inc., Latham, NY (United States); Fritz Intwala, Katrina [Plug Power Inc., Latham, NY (United States)

    2009-08-01

    Plug Power and BASF have conducted eight years of development work prior to this project, demonstrating the potential of PBI membranes to exceed many DOE technical targets. This project consisted of; 1.The development of a worldwide system architecture; 2.Stack and balance of plant module development; 3.Development of an improved, lower cost MEA electrode; 4.Receipt of an improved MEA from the EU consortium; 5.Integration of modules into a system; and 6.Delivery of system to EU consortium for additional integration of technologies and testing.

  17. Potential of ORC Systems to Retrofit CHP Plants in Wastewater Treatment Stations

    Directory of Open Access Journals (Sweden)

    Ricardo Chacartegui

    2013-12-01

    Full Text Available Wastewater treatment stations take advantage of the biogas produced from sludge in anaerobic digesters to generate electricity (reciprocating gas engines and heat (cooling water and engine exhaust gases. A fraction of this electricity is used to operate the plant while the remaining is sold to the grid. Heat is almost entirely used to support the endothermic anaerobic digestion and a minimum fraction of it is rejected to the environment at a set of fan coolers. This generic description is applicable to on-design conditions. Nevertheless, the operating conditions of the plant present a large seasonal variation so it is commonly found that the fraction of heat rejected to the atmosphere increases significantly at certain times of the year. Moreover, the heat available in the exhaust gases of the reciprocating engine is at a very high temperature (around 650 oC, which is far from the temperature at which heat is needed for the digestion of sludge (around 40 oC in the digesters. This temperature difference offers an opportunity to introduce an intermediate system between the engines and the digesters that makes use of a fraction of the available heat to convert it into electricity. An Organic Rankine Cycle (ORC with an appropriate working fluid is an adequate candidate for these hot/cold temperature sources. In this paper, the techno-economic effect of adding an Organic Rankine Cycle as the intermediate system of an existing wastewater treatment station is analysed. On this purpose, different working fluids and system layouts have been studied for a reference wastewater treatment station giving rise to optimal systems configurations. The proposed systems yield very promising results with regard to global efficiency and electricity production (thermodynamically and economically.

  18. Sizing a solar dish Stirling micro-CHP system for residential application in diverse climatic conditions based on 3E analysis

    International Nuclear Information System (INIS)

    Moghadam, Ramin Shabanpour; Sayyaadi, Hoseyn; Hosseinzade, Hadi

    2013-01-01

    Highlights: • 3E analysis was performed on solar CHP systems. • Significant primary energy saving and greenhouse gas reduction were obtained. • The engine was sized so that it had the best economic sound. • Various criteria at different weathers were used for sizing the engine. - Abstract: A solar dish Stirling cogeneration system is considered to provide energy demands of a residential building. As energy demands of the building and output power of the engine are functions of weather condition and solar irradiation flux, the benchmark building was considered to be located in five different cities in Iran with diverse climatic and solar irradiation conditions. The proposed solar dish Stirling micro-CHP system was analyzed based on 3E analysis. The 3E analysis evaluated primary energy saving analysis (energy analysis), carbon dioxide emission reduction (environmental analysis) and payback period for return of investment (economic analysis) and was compared to a reference building that utilized primary energy carriers for its demands. Three scenarios were considered for assessment and sizing the solar dish Stirling engine. In the first scenario, size of the solar dish Stirling engine was selected based on the lowest annual electric power demand while, in second, the highest annual electric power consumption was considered to specify size of the engine. In the third scenario, a solar dish Stirling engine with constant output capacity was considered for the five locations. It was shown that implementing the solar dish Stirling micro-CHP system had good potential in primary energy saving and carbon dioxide emission reduction in all scenarios and acceptable payback period for return of the investment in some scenarios. Finally, the best scenario for selecting size of the engine in each city was introduced using the TOPSIS decision making method. It was demonstrated that, for dry weather, the first scenario was the best while, for hot and humid cities and

  19. Toxin-antitoxin loci as stress-response-elements: ChpAK/MazF and ChpBK cleave translated RNAs and are counteracted by tmRNA

    DEFF Research Database (Denmark)

    Christensen, S.K.; Pedersen, K.; Hansen, Flemming G.

    2003-01-01

    Prokaryotic chromosomes encode toxin-antitoxin loci, often in multiple copies. In most cases, the function of these genes is not known. The chpA (mazEF) locus of Escherichia coli has been described as a cell killing module that induces bacterial apoptosis during nutritional stress. However, we...... found recently that ChpAK (MazF) does not confer cell killing but rather, induces a bacteriostatic condition from which the cells could be resuscitated. Results presented here yield a mechanistic explanation for the detrimental effect on cell growth exerted by ChpAK and the homologous ChpBK protein of E......AK cleaved tmRNA in its coding region. Thus, ChpAK and ChpBK inhibit translation by a mechanism very similar to that of E. coli RelE. On the basis of these results, we propose a model that integrates TA loci into general prokaryotic stress physiology....

  20. EPA's Air Quality Rules for Reciprocating Internal Combustion Engines (RICE) and their Application to CHP (Webinar) – June 24, 2014

    Science.gov (United States)

    This webinar discusses the effect of EPA's air quality regulations on CHP facilities and stationary RICE, and describes how CHP systems can comply with air quality regulations by using stationary RICE.

  1. The concept of system for chips production need to work demo CHP plant in company 'AGROSAVA' from Šimanovci

    Directory of Open Access Journals (Sweden)

    Dedić Aleksandar Đ.

    2014-01-01

    Full Text Available In this paper according to the calculation of chips productivity needs for gasification in the demo CHP plant for co-generation: electricity and heat, chippers were analyzed due to: the type of mobility, running for chipping and the method of delivering chips to temporary yard. The plant was planned to generate electricity power up to 200kWelec. First, in consideration were taken the chippers with medium capacity, which mainly served for chipping brushwood and leaves that remain after harvest plantations on mostly flat terrain and parks. Later, the comparative characteristics of the world's three largest manufacturers of machinery for the production of wood chips significantly larger amounts (up to 30m3/h were given. These chippers were particularly suitable for the higher density of crops and stationed yard, in which brushwood would be brought and chip. At the end, the types of convective dryers were analyzed that could be successfully used for drying wood chips (drum and pneumatic dryer and based on the calculation proposed the types of dryers that were available in the local market.

  2. Is micro-CHP price controllable under price signal controlled Virtual Power Plants?

    DEFF Research Database (Denmark)

    You, Shi; Træholt, Chresten; Poulsen, Bjarne

    2011-01-01

    As micro-combined heat and power (micro-CHP) systems move towards mass deployment together with other kinds of distributed energy resources (DER), an increasing emphasis has been placed on how to coordinate such a large diversified DER portfolio in an efficient way by the Virtual Power Plant (VPP...... for three different micro-CHP systems to investigate the feasibility of being controlled by price. Such analysis is relevant for both controller designs for micro-CHP systems and VPP related operations. The results indicate that controlling the micro-CHP systems by price is feasible but could result...

  3. Elimination of restraints on the propagation of combined heat and power (CHP) generation systems in Switzerland; Beseitigung von Hemmnissen bei der Verbreitung von Waermekraftkopplung (WKK) in der Schweiz

    Energy Technology Data Exchange (ETDEWEB)

    Rieder, S.; Landis, F. [Interface Politikstudien Forschung Beratung, Luzern (Switzerland); Lienhard, A.; Marti Locher, F. [Universitaet Bern, Kompetenzzentrum fuer Public Management (KPM), Bern (Switzerland); Krummenacher, S. [Enerprice Partners AG, Technopark Luzern, Root Laengenbold (Switzerland)

    2009-04-15

    This report for the Swiss Federal Office of Energy (SFOE) discusses the results of study initiated by the SFOE that was to investigate the reasons for the low level of proliferation of CHP technology in Switzerland. The two main questions asked - which factors inhibit the use of CHP in particular application areas and which energy-policy measures can remove such obstacles - are discussed. The use of CHP in various areas of application from waste incineration plants through to units used in residential buildings is analysed and commented on. Recommendations on measures that can be taken to enhance the use of CHP are discussed. Three strategy variants available to the public services area are presented and discussed. It is noted that a consensus between players in the technical and political areas is necessary

  4. Development of a CHP/DH system for the new town of Parand: An opportunity to mitigate global warming in Middle East

    International Nuclear Information System (INIS)

    Mostafavi Tehrani, S. Saeed; Saffar-Avval, M.; Mansoori, Z.; Behboodi Kalhori, S.; Abbassi, A.; Dabir, B.; Sharif, M.

    2013-01-01

    As a result of the worldwide concern about global warming, projects that target reduction of greenhouse gas emissions have gained a lot of interest. The idea of this paper is to recover exhaust hot gases of an existing gas turbine power plant to meet dynamic thermal energy requirements of a residential area (the new town of Parand) situated in the suburb of Tehran, and also use the rest of the heat source potential to feed a steam turbine cycle. In close proximity to this town, there are two GT plants: Parand (954 MW e ) and Rudeshur (790 MW e ). For handling the CHP/STC/DH plant, two methods are considered along with thermal load following operation strategy: maximum power generation (MPG) and minimum fuel consumption (MFC). Then, the alternatives are compared in terms of annual PES, CO 2 abatement and NPV. For the best design from environmental viewpoint (Parand CHP-B), PES, CO 2 abatement and NPV are calculated to be 27.31%, 2.56 million tons and 1491 million dollar, respectively. -- Highlights: • To propose a technical and financial methodology to evaluate CHP/DH projects. • To address environmental advantages of CHPs with conventional plants. • To present practical operation strategies to increase benefits of CHP/DH plants. • To report/compare benefits of various CHP/DH alternatives for a case study in Iran. • To conduct a comprehensive energy analysis of proposed CHP/DH design options

  5. CHP plant Legionowo Poland - Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-12-01

    In 1997, a new Energy Law was passed in Poland. An important element of the law is that local energy planning is made obligatory. The law describes obligatory tasks and procedures for Polish municipalities related to planning and organisation of the energy sector. With the objective of supporting the Polish municipalities in their obligations according to the energy law of 1997, the project 'Energy Planning in Poland at Municipal Level - Support to Decision Makers' was launched. As part of the project, Municipal Guideline Reports have been elaborated for three model municipalities. These guidelines present the basis for the Energy Supply Plans in these municipalities. For the city of Legionowo, the following was recommended: 1. The planning processes initiated during the project should be continues/followed up, 2. Master Plan for the district heating system should be prepared, 3. The possibilities of establishment of a major natural gas-fired CHP plant of the Combined Cycle type should be investigated. The present report is the final Master Plan based on the following reports: Master Plan for Legionowo - Status Report; Master Plan for Legionowo - Hydraulic Analysis; CHP Plant Legionowo Poland - CHP Feasibility Analysis. The final Master Plan describes the status in the DH Company in Legionowo, possible improvements and an investment plan for the selected scenario. (BA)

  6. Decentralised CHP in a competitive market

    DEFF Research Database (Denmark)

    Lund, Henrik

    2004-01-01

    The article agues that decentralised CHP plants is an important part of energy supply in Denmark.......The article agues that decentralised CHP plants is an important part of energy supply in Denmark....

  7. Combined Heat and Power (CHP) Partnership

    Science.gov (United States)

    The CHP Partnership seeks to reduce air pollution and water usage associated with electric power generation by promoting the use of CHP. The Partnership works to remove policy barriers and to facilitate the development of new projects.

  8. Development and Testing of the Advanced CHP System Utilizing the Off-Gas from the Innovative Green Coke Calcining Process in Fluidized Bed

    Energy Technology Data Exchange (ETDEWEB)

    Chudnovsky, Yaroslav [Gas Technology Inst., Des Plaines, IL (United States); Kozlov, Aleksandr [Gas Technology Inst., Des Plaines, IL (United States)

    2013-08-15

    Green petroleum coke (GPC) is an oil refining byproduct that can be used directly as a solid fuel or as a feedstock for the production of calcined petroleum coke. GPC contains a high amount of volatiles and sulfur. During the calcination process, the GPC is heated to remove the volatiles and sulfur to produce purified calcined coke, which is used in the production of graphite, electrodes, metal carburizers, and other carbon products. Currently, more than 80% of calcined coke is produced in rotary kilns or rotary hearth furnaces. These technologies provide partial heat utilization of the calcined coke to increase efficiency of the calcination process, but they also share some operating disadvantages. However, coke calcination in an electrothermal fluidized bed (EFB) opens up a number of potential benefits for the production enhancement, while reducing the capital and operating costs. The increased usage of heavy crude oil in recent years has resulted in higher sulfur content in green coke produced by oil refinery process, which requires a significant increase in the calcinations temperature and in residence time. The calorific value of the process off-gas is quite substantial and can be effectively utilized as an “opportunity fuel” for combined heat and power (CHP) production to complement the energy demand. Heat recovered from the product cooling can also contribute to the overall economics of the calcination process. Preliminary estimates indicated the decrease in energy consumption by 35-50% as well as a proportional decrease in greenhouse gas emissions. As such, the efficiency improvement of the coke calcinations systems is attracting close attention of the researchers and engineers throughout the world. The developed technology is intended to accomplish the following objectives: - Reduce the energy and carbon intensity of the calcined coke production process. - Increase utilization of opportunity fuels such as industrial waste off-gas from the novel

  9. ANALYSIS OF CHP POTENTIAL AT FEDERAL SITES

    Energy Technology Data Exchange (ETDEWEB)

    HADLEY, S.W.

    2002-03-11

    This document was prepared at the request of the U.S. Department of Energy's (DOE's) Federal Energy Management Program (FEMP) under its Technical Guidance and Assistance and Project Financing Programs. The purpose was to provide an estimate of the national potential for combined heat and power (also known as CHP; cogeneration; or cooling, heating, and power) applications at federal facilities and the associated costs and benefits including energy and emission savings. The report provides a broad overview for the U.S. Department of Energy (DOE) and other agencies on when and where CHP systems are most likely to serve the government's best interest. FEMP's mission is to reduce the cost to and environmental impact of the federal government by advancing energy efficiency and water conservation, promoting the use of renewable energy, and improving utility management decisions at federal sites. FEMP programs are driven by its customers: federal agency sites. FEMP monitors energy efficiency and renewable energy technology developments and mounts ''technology-specific'' programs to make technologies that are in strong demand by agencies more accessible. FEMP's role is often one of helping the federal government ''lead by example'' through the use of advanced energy efficiency/renewable energy (EERE) technologies in its own buildings and facilities. CHP was highlighted in the Bush Administration's National Energy Policy Report as a commercially available technology offering extraordinary benefits in terms of energy efficiencies and emission reductions. FEMP's criteria for emphasizing a technology are that it must be commercially available; be proven but underutilized; have a strong constituency and momentum; offer large energy savings and other benefits of interest to federal sites and FEMP mission; be in demand; and carry sufficient federal market potential. As discussed in the report, CHP meets all

  10. Three novel NY-ESO-1 epitopes bound to DRB1*0803, DQB1*0401 and DRB1*0901 recognized by CD4 T cells from CHP-NY-ESO-1-vaccinated patients.

    Science.gov (United States)

    Mizote, Yu; Taniguchi, Taku; Tanaka, Kei; Isobe, Midori; Wada, Hisashi; Saika, Takashi; Kita, Shoichi; Koide, Yukari; Uenaka, Akiko; Nakayama, Eiichi

    2010-07-19

    Three novel NY-ESO-1 CD4 T cell epitopes were identified using PBMC obtained from patients who were vaccinated with a complex of cholesterol-bearing hydrophobized pullulan (CHP) and NY-ESO-1 protein (CHP-NY-ESO-1). The restriction molecules were determined by antibody blocking and using various EBV-B cells with different HLA alleles as APC to present peptides to CD4 T cells. The minimal epitope peptides were determined using various N- and C-termini truncated peptides deduced from 18-mer overlapping peptides originally identified for recognition. Those epitopes were DRB1*0901-restricted NY-ESO-1 87-100, DQB1*0401-restricted NY-ESO-1 95-107 and DRB1*0803-restricted NY-ESO-1 124-134. CD4 T cells used to determine those epitope peptides recognized EBV-B cells or DC that were treated with recombinant NY-ESO-1 protein or NY-ESO-1-expressing tumor cell lysate, suggesting that the epitope peptides are naturally processed. These CD4 T cells showed a cytokine profile with Th1 characteristics. Furthermore, NY-ESO-1 87-100 peptide/HLA-DRB1*0901 tetramer staining was observed. Multiple Th1-type CD4 T cell responses are beneficial for inducing effective anti-tumor responses after NY-ESO-1 protein vaccination. (c) 2010 Elsevier Ltd. All rights reserved.

  11. Micro CHP con motores Stirling

    OpenAIRE

    Aranceta Aguirre, Francisco Javier

    2017-01-01

    Situación actual dela legislación y la tecnología de micro CHP con especial enfoque en la utilización de motores stirling. Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech.

  12. Techno-economic analysis of a coal-fired CHP based combined heating system with gas-fired boilers for peak load compensation

    International Nuclear Information System (INIS)

    Wang Haichao; Jiao Wenling; Lahdelma, Risto; Zou Pinghua

    2011-01-01

    Combined heat and power (CHP) plants dominate the heating market in China. With the ongoing energy structure reformation and increasing environmental concerns, we propose gas-fired boilers to be deployed in underperforming heating substations of heating networks for peak load compensation, in order to improve both energy efficiency and environmental sustainability. However, due to the relatively high price of gas, techno-economic analysis is required for evaluating different combined heating scenarios, characterized by basic heat load ratio (β). Therefore, we employ the dynamic economics and annual cost method to develop a techno-economic model for computing the net heating cost of the system, considering the current state of the art of cogeneration systems in China. The net heating cost is defined as the investment costs and operations costs of the system subtracted by revenues from power generation. We demonstrate the model in a real-life combined heating system of Daqing, China. The results show that the minimum net heating cost can be realized at β=0.75 with a cost reduction of 16.8% compared to coal heating alone. Since fuel cost is the dominating factor, sensitivity analyses on coal and gas prices are discussed subsequently. - Highlights: ► Combined heating systems comply with the energy structure reformation in China. ► We consider the current state of the art of cogeneration systems in China. ► Combined heating systems can be economically more feasible and sustainable. ► The net heating cost of a combined heating system is more sensitive to coal price. ► The optimal basic heat load ratio is more easily influenced by gas price.

  13. Energetic optimization of the performances of a hot air engine for micro-CHP systems working with a Joule or an Ericsson cycle

    International Nuclear Information System (INIS)

    Creyx, M.; Delacourt, E.; Morin, C.; Desmet, B.; Peultier, P.

    2013-01-01

    The micro combined heat and electrical power systems (micro-CHP) with hot air engines are well adapted for solid biomass upgrading, in particular, the Ericsson engines working with an open cycle and an external combustion. This paper presents a model of an Ericsson engine with a compression and an expansion cylinder which allows a thermodynamic optimization of the engine performances in a global approach. A sensitive analysis on the influent parameters is carried out in order to determine the optimal working conditions of the engine: temperature and pressure range, expansion cycle shape with a late intake valve closing or an early exhaust valve closing, heat transfers through the wall of the cylinders. This study, focused on thermodynamic aspects, is a first step in the design of an Ericsson engine. -- Highlights: ► A model of Ericsson engine working with a Joule or Ericsson cycle is presented. ► Influent factors on the engine performances are investigated. ► The heat exchanges in the cylinder wall must be avoided to improve the performances. ► Closing the intake valve late and the exhaust valve early enhances the performances. ► Efficiency, indicated mean pressure, specific work are thermodynamically optimized.

  14. Behind the chlamydial cloak: The replication cycle of chlamydiaphage Chp2, revealed

    International Nuclear Information System (INIS)

    Salim, Omar; Skilton, Rachel J.; Lambden, Paul R.; Fane, Bentley A.; Clarke, Ian N.

    2008-01-01

    Studying the replication of the chlamydiaphages presents significant challenges. Their host bacteria, chlamydiae, have a unique obligate intracellular developmental cycle. Using qPCR, immunochemistry, and electron microscopy, the life cycle of chlamydiaphage Chp2 was characterised. Chp2 infection has a dramatic inhibitory effect on bacterial cell division. The RB to EB transition is arrested and RBs enlarge without further division. There is a phase of rapid Chp2 genome replication 36 to 48 h post infection that is coincident with the expression of viral proteins and the replication of the host chromosome. The end stage of Chp2 replication is characterised by the appearance of paracrystalline structures followed by bacterial cell lysis. These data indicate that the Chp2 life cycle is closely coordinated with the developmental cycle of its bacterial host. This is a remarkable adaptation by a microvirus to infect and replicate in a bacterial host that has an obligate intracellular developmental cycle

  15. Mississippi State University Cooling, Heating, and Power (Micro-CHP) and Bio-Fuel Center

    Energy Technology Data Exchange (ETDEWEB)

    Mago, Pedro [Mississippi State Univ., Mississippi State, MS (United States); Newell, LeLe [Mississippi State Univ., Mississippi State, MS (United States)

    2014-01-31

    Between 2008 and 2014, the U.S. Department of Energy funded the MSU Micro-CHP and Bio-Fuel Center located at Mississippi State University. The overall objective of this project was to enable micro-CHP (micro-combined heat and power) utilization, to facilitate and promote the use of CHP systems and to educate architects, engineers, and agricultural producers and scientists on the benefits of CHP systems. Therefore, the work of the Center focused on the three areas: CHP system modeling and optimization, outreach, and research. In general, the results obtained from this project demonstrated that CHP systems are attractive because they can provide energy, environmental, and economic benefits. Some of these benefits include the potential to reduce operational cost, carbon dioxide emissions, primary energy consumption, and power reliability during electric grid disruptions. The knowledge disseminated in numerous journal and conference papers from the outcomes of this project is beneficial to engineers, architects, agricultural producers, scientists and the public in general who are interested in CHP technology and applications. In addition, more than 48 graduate students and 23 undergraduate students, benefited from the training and research performed in the MSU Micro-CHP and Bio-Fuel Center.

  16. Fuel cells and electrolysers in future energy systems

    DEFF Research Database (Denmark)

    Mathiesen, Brian Vad

    to these conventional technologies, fuel cells have the ability to signifi‐ cantly increase the efficiency of the system while meeting such demands. However, energy system designs can be identified in which the fuel savings achieved are lost in technologies elsewhere in the system. This dissertation is based...... for utilising the full potential of fuel cells. If fuel cells re‐ place gas turbines in combined heat and power (CHP) plants, the improvements may be lost, because a larger part of the heat demand must now be met by boilers. In integrated energy systems with large heat pumps, however, the decreased heat...... in terms of replacing conventional gas turbines. Fuel cells have higher efficiencies than these, also in part load. Fuel cells should not be developed for base load operation, but for flexible regulation in energy systems with large amounts of intermittent renewable energy and CHP plants. Base load plants...

  17. CHP plant Legionowo Poland. Description of the electricity market in Poland/CHP-feasibility analysis

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-04-01

    In 1997, a new energy law was passed in Poland. An important element of the law is that local energy is made obligatory. The law describes obligatory tasks and procedures for the Polish municipalities related to planning and organisation of the energy sector. With the objective of supporting the Polish municipalities in their obligations according to the energy law, the project 'Energy Planning in Poland at Municipal Level - Support to Decision Makers' was launched. As part of the project, Municipal Guideline Reports have been elaborated for three model municipalities. These guidelines present the basis for energy supply plans in the three municipalities. For the city of Legionowo, the following was recommended: 1. The planning processes initiated during the project should be continued/followed up, 2. Master Plan for the district heating system should be prepared, 3. The possibilities of establishment of a major natural gas-fired CHP plant of the combined cycle type should be investigated. The present report describes the electricity market in Poland, the market in which a CHP plant in Legionowo will have to operate. Furthermore the report presents the results of the feasibility analysis carried out for a new CHP plant in Legionowo. (BA)

  18. CHP Integrated with Burners for Packaged Boilers

    Energy Technology Data Exchange (ETDEWEB)

    Castaldini, Carlo; Darby, Eric

    2013-09-30

    The objective of this project was to engineer, design, fabricate, and field demonstrate a Boiler Burner Energy System Technology (BBEST) that integrates a low-cost, clean burning, gas-fired simple-cycle (unrecuperated) 100 kWe (net) microturbine (SCMT) with a new ultra low-NOx gas-fired burner (ULNB) into one compact Combined Heat and Power (CHP) product that can be retrofit on new and existing industrial and commercial boilers in place of conventional burners. The Scope of Work for this project was segmented into two principal phases: (Phase I) Hardware development, assembly and pre-test and (Phase II) Field installation and demonstration testing. Phase I was divided into five technical tasks (Task 2 to 6). These tasks covered the engineering, design, fabrication, testing and optimization of each key component of the CHP system principally, ULNB, SCMT, assembly BBEST CHP package, and integrated controls. Phase I work culminated with the laboratory testing of the completed BBEST assembly prior to shipment for field installation and demonstration. Phase II consisted of two remaining technical tasks (Task 7 and 8), which focused on the installation, startup, and field verification tests at a pre-selected industrial plant to document performance and attainment of all project objectives. Technical direction and administration was under the management of CMCE, Inc. Altex Technologies Corporation lead the design, assembly and testing of the system. Field demonstration was supported by Leva Energy, the commercialization firm founded by executives at CMCE and Altex. Leva Energy has applied for patent protection on the BBEST process under the trade name of Power Burner and holds the license for the burner currently used in the product. The commercial term Power Burner is used throughout this report to refer to the BBEST technology proposed for this project. The project was co-funded by the California Energy Commission and the Southern California Gas Company (SCG), a

  19. The role of combined heat and power (CHP) in energy and climate policy

    International Nuclear Information System (INIS)

    Conrad, F.

    1993-03-01

    In the energy- and environment context CHP is said to be especially energy saving and climate preserving. This report shows that from the standpoint of energy economics as well as under technical aspects this judgement holds true only under special conditions. Depending on the technical parameters, the concrete circumstances of operation and the characteristics of the power plants and heating systems compared to CHP-plants the range of realistic energy savings turns out to be very large. Related overstimations are to a good extend caused by the traditional practice of granting the energetic advantage of CHP exclusively to the district heating. If this advantage is credited to heat and power as equal shares space heating with cogenerated power of 80% efficiency reveals to be very energy conserving. The uno actu utilization of cogenerated heat and power, for the same purpose could facilitate the expansion of CHP, since the problems related to the feeding of cogenerated power into the grid for general purposes would disappear. The second main issue of this report concerns the abatement of CO 2 -emissions with the aid of CHP. Fuelled with natural gas, CHP-plants are attractive instruments for climate policy. This is especially true if CHP is compared to old coal-based power plants and oil-fuelled old heating systems. In the FRG, however, hard coal, and not natural gas, will be the main fuel for future CHP, lowering its CO 2 -advantage considerably. On the other hand high efficient combi-power plants (gas turbine plus condensing turbine) and gas heating systems have to be included in the comparative analyse. Compared to these advanced systems the CO 2 -characteristics of CHP are inferior. Moreover, the specific CO 2 -advantage of natural gas is better used by such modern mono systems rather than CHP-plants. (orig.) [de

  20. CHP plant can do a power of good.

    Science.gov (United States)

    Baillie, Jonathan

    2009-10-01

    With mounting pressure on hospitals and other healthcare facilities to reduce their energy bills, coupled with the need to reduce their carbon footprint, developer and supplier of combined heat and power systems Cogenco argues that adding CHP plant to existing energy generation equipment such as gas boilers has never made greater financial sense. Jonathan Baillie reports.

  1. Do liberalised electricity markets help or hinder CHP and district heating? The case of the UK

    International Nuclear Information System (INIS)

    Toke, David; Fragaki, Aikaterini

    2008-01-01

    This paper investigates whether and how Danish-style combined heat and power (CHP) and district heating (DH) can be implemented in the UK in the context of a liberalised electricity market. There is currently an absence, in the UK, of the Danish system of planning rules and also good tariffs for CHP electricity exports to the grid that led to the development of the Danish system of CHP and DH. However, there are some changes in UK planning practice that may help CHP and DH. These would need to be strengthened, but it is also the case that the way the liberalised electricity market operates in the UK effectively discriminates against small CHP plant selling their electricity to the grid. A Danish system of 'aggregating' CHP-DH plant using thermal stores could help to overcome this problem. However, an alternative strategy would be to establish feed-in tariffs for CHP units that are linked to DH modelled on the Danish 'triple tariff'. This could help the UK's long-term objective of absorbing high levels of fluctuating renewable energy sources

  2. CHP expansion strategy in North Rhine-Westphalia. A blueprint for other regions

    International Nuclear Information System (INIS)

    Holzapfel, Dominik; Schneider, Sabine

    2015-01-01

    The North Rhine-Westphalian state government intends to increase the share of combined heat and power (CHP) generation to at least 25 % by 2020. Since 2013, the campaign ''CHP.NRW - Power Meets Heat'' (''KWK.NRW - Strom trifft Waerme'') of the EnergyAgency.NRW, is has been running on behalf of the NRW Climate Protection Ministry, to publicise this technology and to promote its expansion. The campaign accompanies the State Government's CHP Stimulus Programme. The EnergyAgency.NRW has organised companies and research institutions, associations and interest groups under the umbrella of ''CHP.NRW - Power Meets Heat'', aiming at co-ordinated and intensified activities in the field of combined heat and power generation. The target of the initial-project ''roadmap/CHP.NRW'' of the ''Virtual Institute / CHP.NRW'' is to develop a guideline for the application and optimisation of CHP-systems.

  3. Dynamic modeling and evaluation of solid oxide fuel cell - combined heat and power system operating strategies

    Science.gov (United States)

    Nanaeda, Kimihiro; Mueller, Fabian; Brouwer, Jacob; Samuelsen, Scott

    Operating strategies of solid oxide fuel cell (SOFC) combined heat and power (CHP) systems are developed and evaluated from a utility, and end-user perspective using a fully integrated SOFC-CHP system dynamic model that resolves the physical states, thermal integration and overall efficiency of the system. The model can be modified for any SOFC-CHP system, but the present analysis is applied to a hotel in southern California based on measured electric and heating loads. Analysis indicates that combined heat and power systems can be operated to benefit both the end-users and the utility, providing more efficient electric generation as well as grid ancillary services, namely dispatchable urban power. Design and operating strategies considered in the paper include optimal sizing of the fuel cell, thermal energy storage to dispatch heat, and operating the fuel cell to provide flexible grid power. Analysis results indicate that with a 13.1% average increase in price-of-electricity (POE), the system can provide the grid with a 50% operating range of dispatchable urban power at an overall thermal efficiency of 80%. This grid-support operating mode increases the operational flexibility of the SOFC-CHP system, which may make the technology an important utility asset for accommodating the increased penetration of intermittent renewable power.

  4. Reactive power control with CHP plants - A demonstration

    DEFF Research Database (Denmark)

    Nyeng, Preben; Østergaard, Jacob; Andersen, Claus A.

    2010-01-01

    In this project the potential for ancillary services provision by distributed energy resources is investigated. Specifically, the provision of reactive power control by combined heat and power plants is examined, and the application of the new standard for DER communication systems, IEC 61850...... the substation, and subsequently determines and transmits reactive power setpoint values to the generators in the CHP plant. An important part of the implementation is the communication link between the controller and the CHP plant, which is implemented in compliance with IEC 61850-7-420 using an industrial PC...... platform. In this paper, the implementation and the experience gained is described in more detail. Due to the comprehensiveness of IEC 61850-7-420, the implementation has been a challenging, but achievable task. The test results of the entire control system look promising, but also reveal some issues...

  5. Risk analysis for CHP decision making within the conditions of an open electricity market

    International Nuclear Information System (INIS)

    Al-Mansour, Fouad; Kozuh, Mitja

    2007-01-01

    Decision making under uncertainty is a difficult task in most areas. Investment decisions for combined heat and power production (CHP) are certainly one of the areas where it is difficult to find an optimal solution since the payback period is several years and parameters change due to different perturbing factors of economic and mostly political nature. CHP is one of the most effective measures for saving primary energy and reduction of greenhouse gas emissions. The implementation of EU directives on the promotion of cogeneration based on useful heat demand in the internal energy market will accelerate CHP installation. The expected number of small CHP installations will be very high in the near future. A quick, reliable and simple tool for economic evaluation of small CHP systems is required. Since evaluation is normally made by sophisticated economic computer models which are rather expensive, a simple point estimate economic model was developed which was later upgraded by risk methodology to give more informative results for better decision making. This paper presents a reliable computer model entitled 'Computer program for economic evaluation analysis of CHP' as a tool for analysis and economic evaluation of small CHP systems with the aim of helping the decision maker. The paper describes two methods for calculation of the sensitivity of the economic results to changes of input parameters and the uncertainty of the results: the classic/static method and the risk method. The computer program uses risk methodology by applying RISK software on an existing conventional economic model. The use of risk methodology for economic evaluation can improve decisions by incorporating all possible information (knowledge), which cannot be done in the conventional economic model due to its limitations. The methodology was tested on the case of a CHP used in a smaller hospital

  6. New CHP plant for a rubber products manufacturer

    International Nuclear Information System (INIS)

    Vila, R.; Martí, C.

    2016-01-01

    At the end of 2014 the company Industrias de Hule Galgo decided to undertake the installation project of an efficient CHP plant for its production plant, with the aim of bringing down energy costs and improving the company’s competitive position in the market. The new plant has already started its first operational phase. The project has comprised the installation of a single cycle with gas-powered gensets providing a total electrical capacity of 6.6 MW. This provides the necessary thermal oil for the production plant; covers 100% of the electrical power consumed by the industrial complex; and also generates cooling water, giving improved production capacity by supercooling the extrusion system. To execute these works, Industrias de Hule Galgo contracted the services of engineering company AESA to provide the engineering, procurement and construction of the CHP plant. (Author)

  7. Modeling and optimization of a heat-pump-assisted high temperature proton exchange membrane fuel cell micro-combined-heat-and-power system for residential applications

    DEFF Research Database (Denmark)

    Arsalis, Alexandros; Kær, Søren Knudsen; Nielsen, Mads Pagh

    2015-01-01

    -CHP system assumes heat-led operation, to avoid dumping of heat and the use of complicated thermal energy storage. The overall system is grid-interconnected to allow importing and exporting of electricity as necessary. In this study emphasis is given on the operational characterization of the system......In this study a micro-combined-heat-and-power (micro-CHP) system is coupled to a vapor-compression heat pump to fulfill the residential needs for heating (space heating and water heating) and electricity in detached single-family households in Denmark. Such a combination is assumed to be attractive...... for application, since both fuel cell technology and electric heat pumps are found to be two of the most efficient technologies for generation/conversion of useful energy. The micro-CHP system is fueled with natural gas and includes a fuel cell stack, a fuel processor and other auxiliary components. The micro...

  8. Selection and Exergy Analysis of Fuel Cell System to Meet all Energy Needs of Residential Buildings

    OpenAIRE

    G.R. Ashari; N.Hedayat; S. Shalbaf; E.Hajidavalloo

    2011-01-01

    In this paper a polymer electrolyte membrane (PEM) fuel cell power system including burner, steam reformer, heat exchanger and water heater has been considered to meet the electrical, heating, cooling and domestic hot water loads of residential building which in Tehran. The system uses natural gas as fuel and works in CHP mode. Design and operating conditions of a PEM fuel cell system is considered in this study. The energy requirements of residential building and the num...

  9. Methodology for evaluation of industrial CHP production

    International Nuclear Information System (INIS)

    Pavlovic, Nenad V.; Studovic, Milovan

    2000-01-01

    At the end of the century industry switched from exclusive power consumer into power consumer-producer which is one of the players on the deregulated power market. Consequently, goals of industrial plant optimization have to be changed, making new challenges that industrial management has to be faced with. In the paper is reviewed own methodology for evaluation of industrial power production on deregulated power market. The methodology recognizes economic efficiency of industrial CHP facilities as a main criterion for evaluation. Energy and ecological efficiency are used as additional criteria, in which implicit could be found social goals. Also, methodology recognizes key and limit factors for CHP production in industry. It could be successful applied, by use of available commercial software for energy simulation in CHP plants and economic evaluation. (Authors)

  10. Modelling Danish local CHP on market conditions

    DEFF Research Database (Denmark)

    Ravn, Hans V.; Riisom, Jannik; Schaumburg-Müller, Camilla

    2004-01-01

    In Denmark, the development of local combined heat and power (CHP) plants has been characterised by large growth throughout the nineties, based in part on government subsidies in the form of feed-in tariffs. Simultaneously, there has been a significant growth of wind power, particularly...... with the liberalisation process of the energy sectors of the EU countries, it is however anticipated that Danish local CHP are to begin operating on market conditions within the year 2005. This means that the income that the local CHPs previously gained from selling electricity at the feed-in tariff is replaced in part...

  11. Identification of an operon, Pil-Chp, that controls twitching motility and virulence in Xylella fastidiosa.

    Science.gov (United States)

    Cursino, Luciana; Galvani, Cheryl D; Athinuwat, Dusit; Zaini, Paulo A; Li, Yaxin; De La Fuente, Leonardo; Hoch, Harvey C; Burr, Thomas J; Mowery, Patricia

    2011-10-01

    Xylella fastidiosa is an important phytopathogenic bacterium that causes many serious plant diseases, including Pierce's disease of grapevines. Disease manifestation by X. fastidiosa is associated with the expression of several factors, including the type IV pili that are required for twitching motility. We provide evidence that an operon, named Pil-Chp, with genes homologous to those found in chemotaxis systems, regulates twitching motility. Transposon insertion into the pilL gene of the operon resulted in loss of twitching motility (pilL is homologous to cheA genes encoding kinases). The X. fastidiosa mutant maintained the type IV pili, indicating that the disrupted pilL or downstream operon genes are involved in pili function, and not biogenesis. The mutated X. fastidiosa produced less biofilm than wild-type cells, indicating that the operon contributes to biofilm formation. Finally, in planta the mutant produced delayed and less severe disease, indicating that the Pil-Chp operon contributes to the virulence of X. fastidiosa, presumably through its role in twitching motility.

  12. High expression of MAGE-A4 and MHC class I antigens in tumor cells and induction of MAGE-A4 immune responses are prognostic markers of CHP-MAGE-A4 cancer vaccine.

    Science.gov (United States)

    Saito, Takuro; Wada, Hisashi; Yamasaki, Makoto; Miyata, Hiroshi; Nishikawa, Hiroyoshi; Sato, Eiichi; Kageyama, Shinichi; Shiku, Hiroshi; Mori, Masaki; Doki, Yuichiro

    2014-10-14

    We conducted a cancer vaccine clinical trial with MAGE-A4 protein. Safety, clinical response, and antigen-specific immune responses were analyzed and the prognostic factors by vaccination were investigated. Twenty patients with advanced esophageal, stomach or lung cancer were administered MAGE-A4 vaccine containing 300μg protein subcutaneously once every 2 weeks in six doses. Primary endpoints of this study were safety and MAGE-A4 immune responses. The vaccine was well tolerated. Fifteen of 20 patients completed one cycle of vaccination and two patients showed SD. A MAGE-A4-specific humoral immune response was observed in four patients who had high expression of MAGE-A4 and MHC class I on tumor cells. These four patients showed significantly longer overall survival than patients without an antibody response after vaccination (p=0.009). Patients with tumor cells expressing high MAGE-A4 or MHC class I antigen showed significantly longer overall survival than those with low expression. Induction of CD4 and CD8T cell responses was observed in three and six patients, respectively, and patients with induction of MAGE-A4-specific IFNγ-producing CD8T cells, but not CD4T cells, lived longer than those without induction. The CHP-MAGE-A4 vaccine was safe. Expression of MAGE-A4 and MHC class I in tumor tissue and the induction of a MAGE-A4-specific immune response after vaccination would be feasible prognostic markers for patients vaccinated with MAGE-A4. Copyright © 2014 Elsevier Ltd. All rights reserved.

  13. Reactive power control with CHP plants - A demonstration

    DEFF Research Database (Denmark)

    Nyeng, Preben; Østergaard, Jacob; Andersen, Claus A.

    2010-01-01

    In this project the potential for ancillary services provision by distributed energy resources is investigated. Specifically, the provision of reactive power control by combined heat and power plants is examined, and the application of the new standard for DER communication systems, IEC 61850...... power rating of 7.3 MW on two synchronous generators. A closed-loop control is implemented, that remote controls the CHP plant to achieve a certain reactive power flow in a near-by substation. The solution communicates with the grid operator’s existing SCADA system to obtain measurements from...

  14. Characterization of ultrafine and fine particles from CHP Plants

    Energy Technology Data Exchange (ETDEWEB)

    2009-08-15

    Samples of particles collected at CHP plants in the project 'Survey of emissions from CHP Plants' have been analysed in this project to give information on the morphology and chemical composition of individual particle size classes. The objective of this project was to characterize ultrafine and fine particles emitted to the atmosphere from Danish CHP plants. Nine CHP plants were selected in the Emission Survey Project as being representative for the different types of CHP plants operating in Denmark: 1) Three Waste-to Energy (WTE) plants. 2) Three biomass fired (BM) plants (two straw fired, one wood/saw dust fired). 3) Two gas fired (GF) plants (one natural gas, one landfill gas fired). 4) One gasoil (GO) fired plant. At the WTE and BM plants, various types of emission control systems implemented. The results from these plants represent the composition and size distribution of combustion particles that are emitted from the plants emission control systems. The measured emissions of particles from the waste-to-energy plants WTE1-3 are generally very low. The number and mass concentrations of ultrafine particles (PM{sub 0.1}) were particularly low in the flue gas from WTE2 and WTE3, where bag filters are used for the reduction of particle emissions. The EDX analysis of particles from the WTE plants indicates that the PM{sub 0.1} that penetrates the ECS at WTE can contain high fractions of metals such as Fe, Mn and Cu. The SEM analysis of particles from WTE1-3 showed that the particles were generally porous and irregular in shape. The concentrations of particles in the flue gas from the biomass plants were generally higher than found for the WTE plants. The time series results showed that periodical, high concentration peaks of PM emissions occur from BM1 and BM2. The chemical composition of the particles emitted from the three biomass plants is generally dominated by C, O and S, and to some extend also Fe and Si. A high amount of Cu was found in selected

  15. Distributed m-CHP generation from a small scale concentrated solar power installation

    OpenAIRE

    Crema, Luigi; Roccabruna, Mattia; Alberti, Fabrizio; Restall, Brian; Alamango, K.; Wackelgard, Ewa; Rivolta, Barbara; Hesse, Sebastian; Luminari, Lorenzo; Hislop, Drummond; Sustainable Energy 2014 : the ISE Annual Conference

    2014-01-01

    The present work describes the realization of a modular 1-3 kWe, 3-9 kWth micro Combined Heat and Power (m-CHP) system based on innovative Concentrated Solar Power (CSP) and Stirling engine technology. The cogeneration of energy at distributed level is one of leading argument in large part of energy policies related to renewable energy resources and systems. This CSP m-CHP will provide electrical power, heating and cooling for single and multiple domestic dwellings and other small buildings. ...

  16. Network Capacity Assessment of CHP-based Distributed Generation on Urban Energy Distribution Networks

    Science.gov (United States)

    Zhang, Xianjun

    The combined heat and power (CHP)-based distributed generation (DG) or dis-tributed energy resources (DERs) are mature options available in the present energy market, considered to be an effective solution to promote energy efficiency. In the urban environment, the electricity, water and natural gas distribution networks are becoming increasingly interconnected with the growing penetration of the CHP-based DG. Subsequently, this emerging interdependence leads to new topics meriting serious consideration: how much of the CHP-based DG can be accommodated and where to locate these DERs, and given preexisting constraints, how to quantify the mutual impacts on operation performances between these urban energy distribution networks and the CHP-based DG. The early research work was conducted to investigate the feasibility and design methods for one residential microgrid system based on existing electricity, water and gas infrastructures of a residential community, mainly focusing on the economic planning. However, this proposed design method cannot determine the optimal DG sizing and siting for a larger test bed with the given information of energy infrastructures. In this context, a more systematic as well as generalized approach should be developed to solve these problems. In the later study, the model architecture that integrates urban electricity, water and gas distribution networks, and the CHP-based DG system was developed. The proposed approach addressed the challenge of identifying the optimal sizing and siting of the CHP-based DG on these urban energy networks and the mutual impacts on operation performances were also quantified. For this study, the overall objective is to maximize the electrical output and recovered thermal output of the CHP-based DG units. The electricity, gas, and water system models were developed individually and coupled by the developed CHP-based DG system model. The resultant integrated system model is used to constrain the DG's electrical

  17. Changes of the thermodynamic parameters in failure conditions of the micro-CHP cycle

    Directory of Open Access Journals (Sweden)

    Matysko Robert

    2014-03-01

    Full Text Available The paper presents the calculations for the failure conditions of the ORC (organic Rankine cycle cycle in the electrical power system. It analyses the possible reasons of breakdown, such as the electrical power loss or the automatic safety valve failure. The micro-CHP (combined heat and power system should have maintenance-free configuration, which means that the user does not have to be acquainted with all the details of the ORC system operation. However, the system should always be equipped with the safety control systems allowing for the immediate turn off of the ORC cycle in case of any failure. In case of emergency, the control system should take over the safety tasks and protect the micro-CHP system from damaging. Although, the control systems are able to respond quickly to the CHP system equipped with the inertial systems, the negative effects of failure are unavoidable and always remain for some time. Moreover, the paper presents the results of calculations determining the inertia for the micro-CHP system of the circulating ORC pump, heat removal pump (cooling condenser and the heat supply pump in failure conditions.

  18. The influence of the size of the CHP (combined heat and power) system integrated with a biomass fueled gas generator and piston engine on the thermodynamic and economic effectiveness of electricity and heat generation

    International Nuclear Information System (INIS)

    Skorek-Osikowska, Anna; Bartela, Łukasz; Kotowicz, Janusz; Sobolewski, Aleksander; Iluk, Tomasz; Remiorz, Leszek

    2014-01-01

    This paper analyzes the possibility and the cost of using gas from biomass gasification in the production of electricity and generation of heat using a piston engine in which the power in the supplied biomass is no more than 50 MW. A mathematical model that allows for thermodynamic and economic analysis was designed. The input data regarding the gas generator and the process gas were collected in real experiments on the research installation. Electricity and heat production efficiencies and the electric and heat power of the system were primarily used as indicators of the thermodynamic effectiveness. For the economic analysis, discount methods were adopted that consider the legal and economic environment of such investments. Given the assumptions, the analysis shows that positive economic indicators can characterize the considered systems. The work also included sensitivity analysis of change of the selected characteristic quantities on the evaluation indices. The economic viability of such systems is strongly influenced by many factors, mainly price of fuel and green certificates. When the price of fuel is higher than 9.62 €/GJ or the price of certificates lower than 26.75 €/MWh the NPV (net present value) and NPVR (net present value ratio) indices do not reach positive values for any size of installation. - Highlights: • CHP systems integrated with biomass gasification and piston engine(s) were examined. • An experiment with a biomass-fed gasifier was conducted and the data were used for calculations. • The conditions for economic profitability were determined. • Sensitivity analyses of the influence of the selected quantities were performed. • Price of green certificates and price of fuel are the most important for economic viability

  19. Distributed Control in a Network of Households with microCHP

    NARCIS (Netherlands)

    Larsen, Gunn; Scherpen, Jacquelien M.A.; van Foreest, Nicolaas

    2011-01-01

    This is an application of a dynamic price mechanism to distributed optimization of a network of houses which are both producers and consumers of electricity. One possibility for domestic generation is the Micro Combined Heat Power systemCHP). We use a pricing mechanism based on dual

  20. A price mechanism for supply demand matching in local grid of households with micro-CHP

    NARCIS (Netherlands)

    Larsen, G.K.H.; van Foreest, N.D.; Scherpen, J.M.A.

    2012-01-01

    This paper describes a dynamic price mechanism to coordinate eletric power generation from micro Combined Heat and Power (micro-CHP) systems in a network of households. It is assumed that the households are prosumers, i.e. both producers and consumers of electricity. The control is done on household

  1. Performance and cost results from a DOE Micro-CHP demonstration facility at Mississippi State University

    International Nuclear Information System (INIS)

    Giffin, Paxton K.

    2013-01-01

    Highlights: ► We examine the cost and performance results of a Micro-CHP demonstration facility. ► Evaluation includes both summer and winter performance. ► Evaluation in comparison to a conventional HVAC system using grid power. ► Influence of improperly sized equipment. ► Influence of natural gas prices on the viability of CHP projects using that fuel. - Abstract: Cooling, Heating, and Power (CHP) systems have been around for decades, but systems that utilize 20 kW or less, designated as Micro-CHP, are relatively new. A demonstration site has been constructed at Mississippi State University (MSU) to show the advantages of these micro scale systems. This study is designed to evaluate the performance of a Micro-CHP system as opposed to a conventional high-efficiency Heating, Ventilation, and Air Conditioning (HVAC) system that utilizes electrical power from the existing power grid. Raw data was collected for 7 months to present the following results. The combined cycle efficiency from the demonstration site was averaged at 29%. The average combined boiler and engine cost was $1.8 h −1 of operation for heating season and $3.9 h −1 of operation for cooling season. The cooling technology used, an absorption chiller exhibited an average Coefficient of Performance (COP) of 0.27. The conventional high-efficiency system, during cooling season, had a COP of 4.7 with a combined cooling and building cost of $0.2 h −1 of operation. During heating mode, the conventional system had an efficiency of 47% with a fuel and building electrical cost of $0.28 h −1 of operation.

  2. Biomass combustion gas turbine CHP

    Energy Technology Data Exchange (ETDEWEB)

    Pritchard, D.

    2002-07-01

    This report summarises the results of a project to develop a small scale biomass combustor generating system using a biomass combustor and a micro-gas turbine indirectly fired via a high temperature heat exchanger. Details are given of the specification of commercially available micro-turbines, the manufacture of a biomass converter, the development of a mathematical model to predict the compatibility of the combustor and the heat exchanger with various compressors and turbines, and the utilisation of waste heat for the turbine exhaust.

  3. Integrated Solid Oxide Fuel Cell Power System Characteristics Prediction

    Directory of Open Access Journals (Sweden)

    Marian GAICEANU

    2009-07-01

    Full Text Available The main objective of this paper is to deduce the specific characteristics of the CHP 100kWe Solid Oxide Fuel Cell (SOFC Power System from the steady state experimental data. From the experimental data, the authors have been developed and validated the steady state mathematical model. From the control room the steady state experimental data of the SOFC power conditioning are available and using the developed steady state mathematical model, the authors have been obtained the characteristic curves of the system performed by Siemens-Westinghouse Power Corporation. As a methodology the backward and forward power flow analysis has been employed. The backward power flow makes possible to obtain the SOFC power system operating point at different load levels, resulting as the load characteristic. By knowing the fuel cell output characteristic, the forward power flow analysis is used to predict the power system efficiency in different operating points, to choose the adequate control decision in order to obtain the high efficiency operation of the SOFC power system at different load levels. The CHP 100kWe power system is located at Gas Turbine Technologies Company (a Siemens Subsidiary, TurboCare brand in Turin, Italy. The work was carried out through the Energia da Ossidi Solidi (EOS Project. The SOFC stack delivers constant power permanently in order to supply the electric and thermal power both to the TurboCare Company and to the national grid.

  4. Micro Cooling, Heating, and Power (Micro-CHP) and Bio-Fuel Center, Mississippi State University

    Energy Technology Data Exchange (ETDEWEB)

    Louay Chamra

    2008-09-26

    Initially, most micro-CHP systems will likely be designed as constant-power output or base-load systems. This implies that at some point the power requirement will not be met, or that the requirement will be exceeded. Realistically, both cases will occur within a 24-hour period. For example, in the United States, the base electrical load for the average home is approximately 2 kW while the peak electrical demand is slightly over 4 kW. If a 3 kWe micro- CHP system were installed in this situation, part of the time more energy will be provided than could be used and for a portion of the time more energy will be required than could be provided. Jalalzadeh-Azar [6] investigated this situation and presented a comparison of electrical- and thermal-load-following CHP systems. In his investigation he included in a parametric analysis addressing the influence of the subsystem efficiencies on the total primary energy consumption as well as an economic analysis of these systems. He found that an increase in the efficiencies of the on-site power generation and electrical equipment reduced the total monthly import of electricity. A methodology for calculating performance characteristics of different micro-CHP system components will be introduced in this article. Thermodynamic cycles are used to model each individual prime mover. The prime movers modeled in this article are a spark-ignition internal combustion engine (Otto cycle) and a diesel engine (Diesel cycle). Calculations for heat exchanger, absorption chiller, and boiler modeling are also presented. The individual component models are then linked together to calculate total system performance values. Performance characteristics that will be observed for each system include maximum fuel flow rate, total monthly fuel consumption, and system energy (electrical, thermal, and total) efficiencies. Also, whether or not both the required electrical and thermal loads can sufficiently be accounted for within the system

  5. Putney Basketville Site Biomass CHP Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Hunsberger, Randolph [National Renewable Energy Lab. (NREL), Golden, CO (United States); Mosey, Gail [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2013-10-01

    The U.S. Environmental Protection Agency (EPA) Office of Solid Waste and Emergency Response Center for Program Analysis developed the RE-Powering America's Land initiative to reuse contaminated sites for renewable energy generation when aligned with the community's vision for the site. The Putney, Vermont, Basketville site, formerly the location of a basket-making facility and a paper mill andwoolen mill, was selected for a feasibility study under the program. Biomass was chosen as the renewable energy resource based on abundant woody-biomass resources available in the area. Biomass combined heat and power (CHP) was selected as the technology due to nearby loads, including Putney Paper and Landmark College.

  6. Nanogel antigenic protein-delivery system for adjuvant-free intranasal vaccines

    Science.gov (United States)

    Nochi, Tomonori; Yuki, Yoshikazu; Takahashi, Haruko; Sawada, Shin-Ichi; Mejima, Mio; Kohda, Tomoko; Harada, Norihiro; Kong, Il Gyu; Sato, Ayuko; Kataoka, Nobuhiro; Tokuhara, Daisuke; Kurokawa, Shiho; Takahashi, Yuko; Tsukada, Hideo; Kozaki, Shunji; Akiyoshi, Kazunari; Kiyono, Hiroshi

    2010-07-01

    Nanotechnology is an innovative method of freely controlling nanometre-sized materials. Recent outbreaks of mucosal infectious diseases have increased the demands for development of mucosal vaccines because they induce both systemic and mucosal antigen-specific immune responses. Here we developed an intranasal vaccine-delivery system with a nanometre-sized hydrogel (`nanogel') consisting of a cationic type of cholesteryl-group-bearing pullulan (cCHP). A non-toxic subunit fragment of Clostridium botulinum type-A neurotoxin BoHc/A administered intranasally with cCHP nanogel (cCHP-BoHc/A) continuously adhered to the nasal epithelium and was effectively taken up by mucosal dendritic cells after its release from the cCHP nanogel. Vigorous botulinum-neurotoxin-A-neutralizing serum IgG and secretory IgA antibody responses were induced without co-administration of mucosal adjuvant. Importantly, intranasally administered cCHP-BoHc/A did not accumulate in the olfactory bulbs or brain. Moreover, intranasally immunized tetanus toxoid with cCHP nanogel induced strong tetanus-toxoid-specific systemic and mucosal immune responses. These results indicate that cCHP nanogel can be used as a universal protein-based antigen-delivery vehicle for adjuvant-free intranasal vaccination.

  7. Operational Strategies for a Portfolio of Wind Farms and CHP Plants in a Two-Price Balancing Market

    DEFF Research Database (Denmark)

    Hellmers, Anna; Zugno, Marco; Skajaa, Anders

    2015-01-01

    -horizon fashion, so that forecasts for heat demand, wind power production and market prices are updated at each iteration. We conclude that the portfolio strategy is the most profitable due to the two-price structure of the balancing market. This encourages producers to handle their imbalances outside the market.......In this paper we explore the portfolio effect of a system consisting of a Combined Heat and Power (CHP) plant and a wind farm. The goal is to increase the overall profit of the portfolio by reducing imbalances, and consequently their implicit penalty in a two-price balancing market for electricity....... We investigate two different operational strategies, which differ in whether the CHP plant and the wind farm are operated jointly or independently, and we evaluate their economic performance on a real case study based on a CHP-wind system located in the western part of Denmark. We present...

  8. Energy-optimisation of biogas-fuelled CHP units; Energetische Optimierung von Biogas-BHKW's

    Energy Technology Data Exchange (ETDEWEB)

    Soltic, P.; Edenhauser, D.; Winkler, A.

    2008-07-15

    This illustrated final report for the Swiss Federal office of Energy (SFOE) reports on the energy-related optimisation of combined heat and power (CHP) units that are fuelled with non-processed biogas. Ways of increasing the efficiency of these units as far as the production of electricity is concerned are examined and commented on. Also, ways of using the heat generated by the CHP units to produce electricity using other, exergetic means are also described. Systems such as Stirling engines and existing and new thermo-electrical elements are discussed. The economic viability of the systems is also discussed.

  9. Computer experimental analysis of the CHP performance of a 100 kW e SOFC Field Unit by a factorial design

    Science.gov (United States)

    Calì, M.; Santarelli, M. G. L.; Leone, P.

    Gas Turbine Technologies (GTT) and Politecnico di Torino, both located in Torino (Italy), have been involved in the design and installation of a SOFC laboratory in order to analyse the operation, in cogenerative configuration, of the CHP 100 kW e SOFC Field Unit, built by Siemens-Westinghouse Power Corporation (SWPC), which is at present (May 2005) starting its operation and which will supply electric and thermal power to the GTT factory. In order to take the better advantage from the analysis of the on-site operation, and especially to correctly design the scheduled experimental tests on the system, we developed a mathematical model and run a simulated experimental campaign, applying a rigorous statistical approach to the analysis of the results. The aim of this work is the computer experimental analysis, through a statistical methodology (2 k factorial experiments), of the CHP 100 performance. First, the mathematical model has been calibrated with the results acquired during the first CHP100 demonstration at EDB/ELSAM in Westerwoort. After, the simulated tests have been performed in the form of computer experimental session, and the measurement uncertainties have been simulated with perturbation imposed to the model independent variables. The statistical methodology used for the computer experimental analysis is the factorial design (Yates' Technique): using the ANOVA technique the effect of the main independent variables (air utilization factor U ox, fuel utilization factor U F, internal fuel and air preheating and anodic recycling flow rate) has been investigated in a rigorous manner. Analysis accounts for the effects of parameters on stack electric power, thermal recovered power, single cell voltage, cell operative temperature, consumed fuel flow and steam to carbon ratio. Each main effect and interaction effect of parameters is shown with particular attention on generated electric power and stack heat recovered.

  10. Development of a Wood Powder Fuelled 35 kW Stirling CHP Unit

    DEFF Research Database (Denmark)

    Pålsson, M.; Carlsen, Henrik

    2003-01-01

    due to the slow burning of the fuel. To avoid sintering of ash the flame temperature in a biomass burner has to be quite low. The flame temperature can be lowered by using a high excess air rate; however this will lower system efficiency and needs a large air preheater. By using combustion gas...... recirculation (CGR) a smaller air preheater can be used, while system efficiency will increase compared with using excess air for flame cooling. In a three-year project, a wood powder fuelled Stirling engine CHP unit will be developed and run in field test. The project will use the double-acting four......For biomass fuelled CHP in sizes below 100 kW, Stirling engines are the only feasible alternative today. Using wood powder as fuel, the Stirling engine can be heated directly by the flame like when using a gaseous or liquid fuel burner. However, the combustion chamber will have to be much larger...

  11. THE BREAKEVEN POINT GIVEN LIMIT COST USING BIOMASS CHP PLANT

    Directory of Open Access Journals (Sweden)

    Paula VOICU

    2015-06-01

    Full Text Available Biomass is a renewable source, non-fossil, from which can be obtained fuels, which can be used in power generation systems. The main difference of fossil fuels is the availability biomass in nature and that it is in continue "reproduction". The use its enable the use of materials that could be destined destruction, as a source of energy "renewable", though result with many ecological values. In this paper we will study, applying a calculation model in view optimal sizing of the cogeneration plant based on biomass, biomass cost limit for the net present value is zero. It will consider that in cogeneration systems and in heating peak systems using biomass. After applying the mathematical model for limit value of biomass cost will determine the nominal optimal coefficient of cogeneration, for which discounted net revenue value is zero. Optimal sizing of CHP plants based on using biomass will be given by optimum coefficient of cogeneration determined following the application of the proposed mathematical model.

  12. Energy system analysis of fuel cells and distributed generation

    DEFF Research Database (Denmark)

    Mathiesen, Brian Vad; Lund, Henrik

    2007-01-01

    must be thorough and careful when identifying any imbalances between electricity demand and production from CHP plants (Combined Heat and Power) and fluctuating renewable energy sources. This chapter introduces the energy system analysis model EnergyPLAN, which is one example of a freeware tool, which...... on the energy system in which they are used. Consequently, coherent energy systems analyses of specific and complete energy systems must be conducted in order to evaluate the benefits of FC technologies and in order to be able to compare alternative solutions. In relation to distributed generation, FC...... can be used for such analyses. Moreover, the chapter presents the results of evaluating the overall system fuel savings achieved by introducing different FC applications into different energy systems. Natural gas-based and hydrogen-based micro FC-CHP, natural gas local FC-CHP plants for district...

  13. Renewables and CHP with District Energy in Support of Sustainable Communities

    Energy Technology Data Exchange (ETDEWEB)

    Snoek, Chris

    2010-09-15

    This paper addresses the powerful idea of connecting many energy users to environmentally optimum energy sources through integrated community energy systems. Such systems require piping networks for distributing thermal energy, i.e., district heating and cooling (DHC) systems. The possibilities and advantages of the application of integrated energy concepts are discussed, including the economic and environmental benefits of integrating localized electrical generating systems (CHP), transportation systems, industrial processes and other thermal energy requirements. Examples of a number of operating systems are provided. Some of the R and D carried out by the IEA Implementing Agreement on District Heating and Cooling is also described.

  14. Optimization of operation for combined heat and power plants - CHP plants - with heat accumulators using a MILP formulation

    Energy Technology Data Exchange (ETDEWEB)

    Grue, Jeppe; Bach, Inger [Aalborg Univ. (Denmark). Inst. of Energy Technology]. E-mails: jeg@iet.auc.dk; ib@iet.auc.dk

    2000-07-01

    The power generation system in Denmark is extensively based on small combined heat and power plants (CHP plants), producing both electricity and district heating. This project deals with smaller plants spread throughout the country. Often a heat accumulator is used to enable electricity production, even when the heat demand is low. This system forms a very complex problem, both for sizing, designing and operation of CHP plants. The objective of the work is the development of a tool for optimisation of the operation of CHP plants, and to even considering the design of the plant. The problem is formulated as a MILP-problem. An actual case is being tested, involving CHP producing units to cover the demand. The results from this project show that it is of major importance to consider the operation of the plant in detail already in the design phase. It is of major importance to consider the optimisation of the plant operation, even at the design stage, as it may cause the contribution margin to rise significantly, if the plant is designed on the basis of a de-tailed knowledge of the expected operation. (author)

  15. Modelling of a Biomass Gasification Plant Feeding a Hybrid Solid Oxide Fuel Cell and Micro Gas Turbine System

    DEFF Research Database (Denmark)

    Bang-Møller, Christian; Rokni, Masoud

    2009-01-01

    A system level modelling study on two combined heat and power (CHP) systems both based on biomass gasification. One system converts the product gas in a solid oxide fuel cell (SOFC) and the other in a combined SOFC and micro gas turbine (MGT) arrangement. An electrochemical model of the SOFC has...... been developed and calibrated against published data from Topsoe Fuel Cells A/S (TOFC) and Risø National Laboratory. The modelled gasifier is based on an up scaled version of the demonstrated low tar gasifier, Viking, situated at the Technical University of Denmark. The MGT utilizes the unconverted...

  16. Emissions from decentralised CHP plants 2007 - Energinet.dk Environmental project no. 07/1882. Project report 5 - Emission factors and emission inventory for decentralised CHP production

    Energy Technology Data Exchange (ETDEWEB)

    Nielsen, Malene; Nielsen, Ole-Kenneth; Thomsen, M.

    2010-06-15

    Updated emission factors for decentralised combined heat and power (CHP) plants with a capacity < 25MWe have been estimated based on project emission measurements as well as emission measurements performed in recent years that were collected. The emission factors valid for 2006/2007 have been estimated for the plant technologies: Municipal solid waste (MSW) incineration plants, plants combusting straw or wood, natural gas fuelled reciprocating engines, biogas fuelled engines, natural gas fuelled gas turbines, gas oil fuelled reciprocating engines, gas oil fuelled gas turbines, steam turbines combusting residual oil and reciprocating engines combusting biomass producer gas based on wood. The emission factors for MSW incineration plants are much lower than the emission factors that were estimated for year 2000. The considerable reduction in the emission factors is a result of lower emission limit values in Danish legislation since 2006 that has lead to installation of new and improved flue gas cleaning systems in most MSW incineration plants. For CHP plants combusting wood or straw no major technical improvements have been implemented. The emission factors for natural gas fuelled reciprocating engines have been reduced since year 2000 as a result of technical improvements that have been carried out due to lower emission limit values in Danish legislation. The NO{sub x} emission factor for natural gas fuelled gas turbines has decreased 62 % since year 2000. This is a result of installation of low-NO{sub x} burners in almost all gas turbines that has been necessary to meet new emission limits in Danish legislation. The emission measurements programme included screening of the emissions of HCB, PCB, PCDD/-F and PBDD/-F. Compared to the Danish national emission decentralized CHP plants are major emission sources for CH{sub 4}, NO{sub x}, SO{sub 2}, heavy metals and HCB. (author)

  17. System analysis of CO{sub 2} sequestration from biomass cogeneration plants (Bio-CHP-CCS). Technology, economic efficiency, sustainability; Systemanalyse der CO{sub 2}-Sequestrierung aus Biomasse-Heizkraftwerken (Bio-KWK-CCS). Technik, Wirtschaftlichkeit, Nachhaltigkeit

    Energy Technology Data Exchange (ETDEWEB)

    Hartmann, Claus

    2014-10-15

    In the present work a system analysis is carried out to determine the extent to which a combination of the three areas of energetic biomass use, combined heat and power (CHP) and CO{sub 2} sequestration (CCS - Carbon Capture and Storage) is fundamentally possible and meaningful. The term ''CO{sub 2} sequestration'' refers to the process chain from CO{sub 2} capture, CO{sub 2} transport and CO{sub 2} storage. While the use of biomass in combined heat and power plants is a common practice, CO{sub 2} sequestration (based on fossil fuels) is at the research and development stage. A combination of CCS with biomass has so far been little studied, a combination with combined heat and power plants has not been investigated at all. The two technologies for the energetic use of biomass and cogeneration represent fixed variables in the energy system of the future in the planning of the German federal government. According to the lead scenario of the Federal Ministry of the Environment, electricity generation from biomass is to be almost doubled from 2008 to 2020. At the same time, the heat generated in cogeneration is to be trebled [cf. Nitsch and Wenzel, 2009, p. 10]. At the same time, the CCS technology is to be used in half of all German coal-fired power plants until 2030 [cf. Krassuki et al., 2009, p. 17]. The combination of biomass and CCS also represents an option which is conceivable for the German federal policy [cf. Bundestag, 2008b, p. 4]. In addition, the CCS technology will provide very good export opportunities for the German economy in the future [cf. Federal Government, 2010, p. 20]. The combination of biomass combined heat and power plants with CCS offers the interesting opportunity to actively remove CO{sub 2} from the atmosphere as a future climate protection instrument by means of CO{sub 2} neutrality. Therefore, in the energy concept of the German federal government called for a storage project for industrial or biogenic CO{sub 2

  18. CHP and District Cooling: An Assessment of Market and Policy Potential in India

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-07-01

    This report contains an assessment of India's CHP/DC status and recommendations for addressing barriers to allow India to meet its energy efficiency targets. Such barriers include a lack of governmental emphasis on CHP, the absence of a clear methodology for calculating CO2 emission reductions from CHP/DHC, and a tax and duty structure for CHP capital equipment that is not as attractive as for other renewable energy technologies.

  19. Energy policy responses to the climate change challenge: The consistency of European CHP, renewables and energy efficiency policies

    International Nuclear Information System (INIS)

    Grohnheit, P.E.

    1999-09-01

    This report is Volume 14 of individual reports of the Shared Analysis Project prepared for the European Commission, Directorate General for Energy. The three major objectives of the project were: to design a common framework of energy analysis that aimed to involve all Member States and the experts of industrial research groups (the shared approach to energy analysis); To analyse generic EU-wide issues important for energy policy and for future energy demand and production, putting particular emphasis on world energy market trends, strategic energy policy responses to the Kyoto process, and evaluation of response strategies to increasing energy import dependence and to climate change activities; to carry out quantitative analyses of energy trends and scenarios as an input for discussion. The present volume considers three main issues concerning energy policy responses to the climate change challenge: the penetration of CHP and renewables according to official objectives, focusing on infrastructure and institutions rather than technology; the consistency of promotion of CHP, renewables and energy savings at the same time; consumers' choices and priorities in a liberalised market. The volume describes examples of policies in several Member States for these technologies with emphasis on CHP for both large-scale and small-scale district heating systems. The penetration of CHP technologies is analysed quantitatively using a traditional optimisation model approach for stylised regions with heat markets suitable for CHP and facing a competitive European market for electricity. The Joint Final Report of the project, titled 'Economic Foundations for Energy Policy' is published as a Special Issue of Energy in Europe, December 1999. All reports are available on the Internet, www.shared-analysis.fhg.de/ The project started in January 1998, involving about 100 months of scientific labour. The project consortium consisted of nine member institutes co-ordinated by the Fraunhofer

  20. Energy policy responses to the climate change challenge: The consistency of European CHP, renewables and energy efficiency policies

    Energy Technology Data Exchange (ETDEWEB)

    Grohnheit, P.E.

    1999-09-01

    This report is Volume 14 of individual reports of the Shared Analysis Project prepared for the European Commission, Directorate General for Energy. The three major objectives of the project were: to design a common framework of energy analysis that aimed to involve all Member States and the experts of industrial research groups (the shared approach to energy analysis); To analyse generic EU-wide issues important for energy policy and for future energy demand and production, putting particular emphasis on world energy market trends, strategic energy policy responses to the Kyoto process, and evaluation of response strategies to increasing energy import dependence and to climate change activities; to carry out quantitative analyses of energy trends and scenarios as an input for discussion. The present volume considers three main issues concerning energy policy responses to the climate change challenge: the penetration of CHP and renewables according to official objectives, focusing on infrastructure and institutions rather than technology; the consistency of promotion of CHP, renewables and energy savings at the same time; consumers' choices and priorities in a liberalised market. The volume describes examples of policies in several Member States for these technologies with emphasis on CHP for both large-scale and small-scale district heating systems. The penetration of CHP technologies is analysed quantitatively using a traditional optimisation model approach for stylised regions with heat markets suitable for CHP and facing a competitive European market for electricity. The Joint Final Report of the project, titled 'Economic Foundations for Energy Policy' is published as a Special Issue of Energy in Europe, December 1999. All reports are available on the Internet, www.shared-analysis.fhg.de/ The project started in January 1998, involving about 100 months of scientific labour. The project consortium consisted of nine member institutes co-ordinated by

  1. IVO`s CHP know-how: experience, inventions, patents

    Energy Technology Data Exchange (ETDEWEB)

    Aeijaelae, M.; Ohtonen, V. [ed.

    1997-11-01

    IVO can justly claim mastery in the co-generation of district heat and electricity - CHP. As well as looking at the issue from the viewpoint of planners, builders and operators, IVO`s engineers also view power plants through the eyes of the product developer and inventor. This approach has resulted in successful power plant configurations, inventions and patents and visions

  2. A Stochastic Unit Commitment Model for a Local CHP Plant

    DEFF Research Database (Denmark)

    Ravn, Hans V.; Riisom, Jannik; Schaumburg-Müller, Camilla

    2005-01-01

    Local CHP development in Denmark has during the 90’s been characterised by large growth primarily due to government subsidies in the form of feed-in tariffs. In line with the liberalisation process in the EU, Danish local CHPs of a certain size must operate on market terms from 2005. This paper...

  3. Optimal power flow based TU/CHP/PV/WPP coordination in view of wind speed, solar irradiance and load correlations

    International Nuclear Information System (INIS)

    Azizipanah-Abarghooee, Rasoul; Niknam, Taher; Malekpour, Mostafa; Bavafa, Farhad; Kaji, Mahdi

    2015-01-01

    Highlights: • Formulate probabilistic OPF with VPE, multi-fuel options, POZs, FOR of CHP units. • Propose a new powerful optimization method based on enhanced black hole algorithm. • Coordinate of TUs, WPPs, PVs and CHP units together in the proposed problem. • Evaluate the impacts of inputs’ uncertainties and their correlations on the POPF. • Use the 2m + 1 point estimated method. - Abstract: This paper addresses a novel probabilistic optimisation framework for handling power system uncertainties in the optimal power flow (OPF) problem that considers all the essential factors of great impact in the OPF problem. The object is to study and model the correlation and fluctuation of load demands, photovoltaic (PV) and wind power plants (WPPs) which have an important influence on transmission lines and bus voltages. Moreover, as an important tool of saving waste heat energy in the thermoelectric power plant, the power networks share of combined heat and power (CHP) has increased dramatically in the past decade. So, the probabilistic OPF (POPF) problem considering valve point effects, multi-fuel options and prohibited zones of thermal units (TUs) is firstly formulated. The PV, WPP and CHP units are also modeled. Then, a new method utilizing enhanced binary black hole (EBBH) algorithm and 2m + 1 point estimated method is proposed to solve this problem and to handle the random nature of solar irradiance, wind speed and load of consumers. The correlation between input random variables is considered using a correlation matrix. Finally, numerical results are presented and considered regarding the IEEE 118-busses, including PV, WPP, CHP and TU at several busses. The simulation and comparison results obtained demonstrate the broad advantages and feasibility of the suggested framework in the presence of dependent non-Gaussian distribution of random variables

  4. Integrated HT-PEMFC and multi-fuel reformer for micro CHP. Final report

    Energy Technology Data Exchange (ETDEWEB)

    2010-07-01

    reformed both methane and biogas although the efficiency was low, on the order of 15% due to excessive slip and heat losses. The construction and test of an integrated micro CHP system revealed several problems with the core technology. Therefore, rather than working with the integrated system, individual system components were tested separately. In spite of the problems with the reformer and the fuel cell stack the system was successfully operated and an electric efficiency of 18%{sub LHV} was demonstrated. (Author)

  5. Proliferation of cultured mouse choroid plexus epithelial cells.

    Directory of Open Access Journals (Sweden)

    Basam Z Barkho

    Full Text Available The choroid plexus (ChP epithelium is a multifunctional tissue found in the ventricles of the brain. The major function of the ChP epithelium is to produce cerebrospinal fluid (CSF that bathes and nourishes the central nervous system (CNS. In addition to the CSF, ChP epithelial cells (CPECs produce and secrete numerous neurotrophic factors that support brain homeostasis, such as adult hippocampal neurogenesis. Accordingly, damage and dysfunction to CPECs are thought to accelerate and intensify multiple disease phenotypes, and CPEC regeneration would represent a potential therapeutic approach for these diseases. However, previous reports suggest that CPECs rarely divide, although this has not been extensively studied in response to extrinsic factors. Utilizing a cell-cycle reporter mouse line and live cell imaging, we identified scratch injury and the growth factors insulin-like growth factor 1 (IGF-1 and epidermal growth factor (EGF as extrinsic cues that promote increased CPEC expansion in vitro. Furthermore, we found that IGF-1 and EGF treatment enhances scratch injury-induced proliferation. Finally, we established whole tissue explant cultures and observed that IGF-1 and EGF promote CPEC division within the intact ChP epithelium. We conclude that although CPECs normally have a slow turnover rate, they expand in response to external stimuli such as injury and/or growth factors, which provides a potential avenue for enhancing ChP function after brain injury or neurodegeneration.

  6. Demonstration Stirling Engine based Micro-CHP with ultra-low emissions

    Energy Technology Data Exchange (ETDEWEB)

    Oeberg, Rolf; Olsson, Fredrik [Carl Bro Energikonsult AB (Sweden); Paalsson, Magnus [Lund Inst. of Technology (Sweden)

    2004-03-01

    This project has been initiated in order to develop a new type of natural gas fired low emission combustion system for a Stirling engine CHP-unit, and to demonstrate and evaluate the unit with the newly developed combustion system in a CHP application. The Stirling engine technology is well developed, but mostly used in special applications and CHP-applications are scarce. The very low exhaust emissions with the new combustion system would make the Stirling engine very suitable for installation in as a CHP-unit in domestic areas. The Stirling engine used in the project has been a V161 engine produced by Solo Kleinmotoren GmbH in Sindelfingen. The unit has a nominal output of 7,5 kW{sub el} and 20 kW{sub heat} (Hot water). The new combustion system was developed at Lund University and the very strict emission targets that were set up could be achieved, both in the laboratory tests and during the site-testing period. Typical performance and emission figures measured at the site installation are: Generator output (kW): 7,3; Hot water output (kW): 15; El. efficiency (%): 25,4; Total efficiency (%): 77,8; NO{sub x} (ppm): 14; CO (ppm): 112; HC (ppm): < 1; O{sub 2} (%): 8,0; Noise level 1 m from the unit (dBA): 83. The NO{sub x} emissions were reduced with almost 97 % as compared to a standard Stirling combustion system. The emission figures are considerably lower than what could be achieved in an internal combustion engine of similar size with an oxidation catalyst (report SGC 106), while the performance figures are similar for the two technologies. The site testing was carried out during a period of 1,5 year at a site owned by Goeteborg Energi. The site comprises a building structure with workshops, offices etc. covering a ground area of 2,500 m{sup 2}. A gas fired boiler with an output of 250 kW supplies hot water to a local grid for heating and tap water. The annual heat demand is typically 285 MWh and the hot water temperatures are normally 60-80 deg C. The site

  7. A MATHEMATICAL MODEL OF CHP 2000 TYPE PROGRESSIVE GEAR

    OpenAIRE

    Paweł Lonkwic

    2016-01-01

    The project of CHP2000 type progressive gear has been presented in the article. The offered solution from its construction point of view differs from the existing solutions due to the application of Belleville springs packets supporting the braking roller cam and achieving a flexible range of the gear loading. The standard concept of the gear loading within a mathematical and a geometrical model has been presented in the article. The proposed solution can be used in the friction lifts with th...

  8. IEA ECBCS Annex 42 'FC+GOGEN-SIM'. The simulation of building-integrated fuel cell and other cogeneration systems - Summary; IEA ECBCS Annex 42 'FC+GOGEN-SIM'. The simulation of building-integrated fuel cell and other cogeneration systems - Summary

    Energy Technology Data Exchange (ETDEWEB)

    Dorer, V.

    2008-07-01

    This summary report for the Swiss Federal Office of Energy (SFOE) takes a look at the results of three sub-tasks performed within the framework of an IEA task-annex. The sub-tasks aimed to develop simulation models for fuel-cell appliances and other micro-CHP units and to integrate them into various building simulation programs. The first sub-task covered the compilation of a technology overview as well as household power and hot-water requirements. The second one was devoted to the development of models for micro-CHP units. A third sub-task covered the simulation of various system configurations and evaluated general methods for dealing with energy, emissions and costs. The work done is briefly reviewed and the various institutions involved in the work are noted.

  9. Development and Demonstration of a New Generation High Efficiency 10kW Stationary Fuel Cell System

    Energy Technology Data Exchange (ETDEWEB)

    Howell, Thomas Russell

    2013-04-30

    The overall project objective is to develop and demonstrate a polymer electrolyte membrane fuel cell combined heat and power (PEMFC CHP) system that provides the foundation for commercial, mass produced units which achieve over 40% electrical efficiency (fuel to electric conversion) from 50-100% load, greater than 70% overall efficiency (fuel to electric energy + usable waste heat energy conversion), have the potential to achieve 40,000 hours durability on all major process components, and can be produced in high volumes at under $400/kW (revised to $750/kW per 2011 DOE estimates) capital cost.

  10. Waste Heat Recapture from Supermarket Refrigeration Systems

    Energy Technology Data Exchange (ETDEWEB)

    Fricke, Brian A [ORNL

    2011-11-01

    The objective of this project was to determine the potential energy savings associated with improved utilization of waste heat from supermarket refrigeration systems. Existing and advanced strategies for waste heat recovery in supermarkets were analyzed, including options from advanced sources such as combined heat and power (CHP), micro-turbines and fuel cells.

  11. CHP from Updraft Gasifier and Stirling Engine

    DEFF Research Database (Denmark)

    Jensen, N.; Werling, J.; Carlsen, Henrik

    2002-01-01

    The combination of thermal gasification with a Stirling engine is an interesting concept for use in small combined heat and power plants based on biomass. By combining the two technologies a synergism can potentially be achieved. Technical problems, e.g. gas cleaning and fouling of the Stirling...... engine heat exchanger, can be eliminated and the overall electric efficiency of the system can be improved. At the Technical University of Denmark a Stirling engine fueled by gasification gas has been developed. In this engine the combustion system and the geometry of the hot heat exchanger...... of the Stirling engine has been adapted to the use of a gas with a low specific energy content and a high content of tar and particles. In the spring of 2001 a demonstration plant has been built in the western part of Denmark where this Stirling engine is combined with an updraft gasifier. A mathematical...

  12. A MATHEMATICAL MODEL OF CHP 2000 TYPE PROGRESSIVE GEAR

    Directory of Open Access Journals (Sweden)

    Paweł Lonkwic

    2016-12-01

    Full Text Available The project of CHP2000 type progressive gear has been presented in the article. The offered solution from its construction point of view differs from the existing solutions due to the application of Belleville springs packets supporting the braking roller cam and achieving a flexible range of the gear loading. The standard concept of the gear loading within a mathematical and a geometrical model has been presented in the article. The proposed solution can be used in the friction lifts with the loading capacity from 8500 up to 20000 N.

  13. Network design optimization of fuel cell systems and distributed energy devices.

    Energy Technology Data Exchange (ETDEWEB)

    Colella, Whitney G.

    2010-07-01

    This research explores the thermodynamics, economics, and environmental impacts of innovative, stationary, polygenerative fuel cell systems (FCSs). Each main report section is split into four subsections. The first subsection, 'Potential Greenhouse Gas (GHG) Impact of Stationary FCSs,' quantifies the degree to which GHG emissions can be reduced at a U.S. regional level with the implementation of different FCS designs. The second subsection, 'Optimizing the Design of Combined Heat and Power (CHP) FCSs,' discusses energy network optimization models that evaluate novel strategies for operating CHP FCSs so as to minimize (1) electricity and heating costs for building owners and (2) emissions of the primary GHG - carbon dioxide (CO{sub 2}). The third subsection, 'Optimizing the Design of Combined Cooling, Heating, and Electric Power (CCHP) FCSs,' is similar to the second subsection but is expanded to include capturing FCS heat with absorptive cooling cycles to produce cooling energy. The fourth subsection, - Thermodynamic and Chemical Engineering Models of CCHP FCSs,' discusses the physics and thermodynamic limits of CCHP FCSs.

  14. Implementation strategy for small CHP-plants in a competitive market

    DEFF Research Database (Denmark)

    Lund, Henrik; Šiupšinskas, G.; Martinaitis, V.

    2005-01-01

    The article analyses the conditions for the replacement of boilers in the existing district-heating supplies with combined heat-and-power production (CHP) in Lithuania.......The article analyses the conditions for the replacement of boilers in the existing district-heating supplies with combined heat-and-power production (CHP) in Lithuania....

  15. Energy and economic effects of CHP with combined technologies of corn cobs gasification and gas turbines

    Directory of Open Access Journals (Sweden)

    Guteša Milana M.

    2016-01-01

    Full Text Available This paper presents the performance and economic analysis of the gas turbine with co-firing gas from corn cob gasification and natural gas. Adiabatic and non-adiabatic expansion in the turbine is considered. The analysis is performed parametrically with corn cob gasification gas and natural gas ratio. The volumetric energy content of fuels with different share of gas from the corn cob gasification therefore, with different calorific values, is compared by means of the Wobbe Index. In energy and economic analyses, the following configurations are dealt with: single manifold, dual manifold and separate gas systems. [Projekat Ministarstva nauke Republike Srbije, br. 33049: The Development of CHP Demonstration Plant with Biomass Gasification

  16. Technical Analysis of Installed Micro-Combined Heat and Power Fuel-Cell System

    Energy Technology Data Exchange (ETDEWEB)

    Brooks, Kriston P.; Makhmalbaf, Atefe

    2014-10-31

    Combined heat and power fuel cell systems (CHP-FCSs) provide consistent electrical power and hot water with greater efficiency and lower emissions than alternative sources. These systems can be used either as baseload, grid-connected, or as off-the-grid power sources. This report presents a technical analysis of 5 kWe CHP-FCSs installed in different locations in the U.S. At some sites as many as five 5 kWe system is used to provide up to 25kWe of power. Systems in this power range are considered “micro”-CHP-FCS. To better assess performance of micro-CHP-FCS and understand their benefits, the U.S. Department of Energy worked with ClearEdge Power to install fifteen 5-kWe PBI high temperature PEM fuel cells (CE5 models) in the commercial markets of California and Oregon. Pacific Northwest National Laboratory evaluated these systems in terms of their economics, operations, and technical performance. These units were monitored from September 2011 until June 2013. During this time, about 190,000 hours of data were collected and more than 17 billion data points were analyzed. Beginning in July 2013, ten of these systems were gradually replaced with ungraded systems (M5 models) containing phosphoric acid fuel cell technology. The new units were monitored until June 2014 until they went offline because ClearEdge was bought by Doosan at the time and the new manufacturer did not continue to support data collection and maintenance of these units. During these two phases, data was collected at once per second and data analysis techniques were applied to understand behavior of these systems. The results of this analysis indicate that systems installed in the second phase of this demonstration performed much better in terms of availability, consistency in generation, and reliability. The average net electrical power output increased from 4.1 to 4.9 kWe, net heat recovery from 4.7 to 5.4 kWth, and system availability improved from 94% to 95%. The average net system electric

  17. Experimental development, 1D CFD simulation and energetic analysis of a 15 kw micro-CHP unit based on reciprocating internal combustion engine

    International Nuclear Information System (INIS)

    Muccillo, M.; Gimelli, A.

    2014-01-01

    Cogeneration is commonly recognized as one of the most effective solutions to achieve the increasingly stringent reduction in primary energy consumption and greenhouse emissions. This characteristic led to the adoption of specific directives promoting this technique. In addition, a strategic role in power reliability is recognized to distributed generation. The study and prototyping of cogeneration plants, therefore, has involved many research centres. This paper deals with energetic aspects of CHP referring to the study of a 15 kW micro-CHP plant based on a LPG reciprocating engine designed, built and grid connected. The plant consists of a heat recovery system characterized by a single water circuit recovering heat from exhaust gases, from engine coolant and from the energy radiated by the engine within the shell hosting the plant. Some tests were carried out at whole open throttle and the experimental data were collected. However it was needed to perform a 1D thermo-fluid dynamics simulation of the engine to completely characterize the micro-CHP. As the heat actually recovered depends on the user's thermal load, particularly from the required temperature's level, a comparison of the results for six types of users were performed: residential, hospital, office, commercial, sports, hotel. Both Italian legislative indexes IRE and LT were evaluated, as defined by A.E.E.G resolution n. 42/02 and subsequent updates, as well as the plant's total Primary Energy Saving. - Highlights: • This paper deals with energetic aspects of CHP referring to the study of a 15 kW micro-CHP plant. • The 15 kW micro-CHP plant is based on a GPL reciprocating engine designed, built and grid connected. • Some tests were carried out at whole open throttle and the experimental data were collected. • It was needed to perform a 1D thermo-fluid dynamics simulation of the engine to completely characterize the micro-CHP. • The analysed solution is particularly suited for

  18. Dose-dependent effects of NY-ESO-1 protein vaccine complexed with cholesteryl pullulan (CHP-NY-ESO-1) on immune responses and survival benefits of esophageal cancer patients.

    Science.gov (United States)

    Kageyama, Shinichi; Wada, Hisashi; Muro, Kei; Niwa, Yasumasa; Ueda, Shugo; Miyata, Hiroshi; Takiguchi, Shuji; Sugino, Sahoko H; Miyahara, Yoshihiro; Ikeda, Hiroaki; Imai, Naoko; Sato, Eiichi; Yamada, Tomomi; Osako, Masaharu; Ohnishi, Mami; Harada, Naozumi; Hishida, Tadashi; Doki, Yuichiro; Shiku, Hiroshi

    2013-10-05

    Cholesteryl pullulan (CHP) is a novel antigen delivery system for cancer vaccines. This study evaluated the safety, immune responses and clinical outcomes of patients who received the CHP-NY-ESO-1 complex vaccine, Drug code: IMF-001. Patients with advanced/metastatic esophageal cancer were enrolled and subcutaneously vaccinated with either 100 μg or 200 μg of NY-ESO-1 protein complexed with CHP. The primary endpoints were safety and humoral immune responses, and the secondary endpoint was clinical efficacy. A total of 25 patients were enrolled. Thirteen and twelve patients were repeatedly vaccinated with 100 μg or 200 μg of CHP-NY-ESO-1 with a median of 8 or 9.5 doses, respectively. No serious adverse events related to the vaccine were observed. Three out of 13 patients in the 100-μg cohort and 7 out of 12 patients in the 200-μg cohort were positive for anti-NY-ESO-1 antibodies at baseline. In the 100-μg cohort, an antibody response was observed in 5 out of 10 pre-antibody-negatives patients, and the antibody levels were augmented in 2 pre-antibody-positive patients after vaccination. In the 200-μg cohort, all 5 pre-antibody-negative patients became seropositive, and the antibody level was amplified in all 7 pre-antibody-positive patients. No tumor shrinkage was observed. The patients who received 200 μg of CHP-NY-ESO-1 survived longer than patients receiving 100 μg of CHP-NY-ESO-1, even those who exhibited unresponsiveness to previous therapies or had higher tumor burdens. The safety and immunogenicity of CHP-NY-ESO-1 vaccine were confirmed. The 200 μg dose more efficiently induced immune responses and suggested better survival benefits. (Clinical trial registration number NCT01003808).

  19. A microeconomic analysis of decentralized small scale biomass based CHP plants—The case of Germany

    International Nuclear Information System (INIS)

    Wittmann, Nadine; Yildiz, Özgür

    2013-01-01

    Alternative energy sources, such as biomass CHP plants, have recently gained significantly in importance and action is due both on the large scale corporate level and on the small scale. Hence, making the scope and economic outline of such projects easily intelligible without losing relevant details seems a key factor to further promote the necessary developments. The model setup presented in this paper may therefore serve as a starting point for generating numerical results based on real life cases or scenarios. Its focus lies on the economic analysis of decentralized biomass CHP plants. It presents a new approach to analyzing the economic aspects of biomass CHP plants implementing a formal microeconomic approach. As Germany claims a leading role in the market for renewable energy production, the paper also takes a closer look on the effects of German energy policy with respect to biomass CHP plants. - Highlights: • A formal microeconomic model is used to analyse a decentralized biomass CHP plant. • Model setup is used to generate numerical results based on real life scenarios. • Nested CES production function is a new approach to model economics of biomass CHP. • Analysis presents insight into microeconomics and cost drivers of biomass CHP. • Evaluation of energy policy design with respect to environmental policy goals

  20. Small-scale biomass CHP using gasa turbines: a scoping study

    International Nuclear Information System (INIS)

    James, D.W.; Landen, R.

    1996-01-01

    Various options for small-scale (up to 250 KWe) Combined Heat and Power (CHP) plants evaluated in this scoping study. Plants using small gas turbines, and able to use biomass fuels when available are included. Three detailed case studies of small-scale biomass CHP plants are compared to match specific technical options with customer requirements. The commercial development of such biomass-fired CHP units, using gas turbines, is shown to be economically viable depending on fuel costs and the continuation of existing financial incentives. (UK)

  1. Should a small combined heat and power plant (CHP) open to its regional power and heat networks? Integrated economic, energy, and emergy evaluation of optimization plans for Jiufa CHP

    International Nuclear Information System (INIS)

    Peng, T.; Lu, H.F.; Wu, W.L.; Campbell, D.E.; Zhao, G.S.; Zou, J.H.; Chen, J.

    2008-01-01

    The development of industrial ecology has led company managers to increasingly consider their company's niche in the regional system, and to develop optimization plans. We used emergy-based, ecological-economic synthesis to evaluate two optimization plans for the Jiufa Combined Heat and Power (CHP) Plant, Shandong China. In addition, we performed economic input-output analysis and energy analysis on the system. The results showed that appropriately incorporating a firm with temporary extra productivity into its regional system will help maximize the total productivity and improve ecological-economic efficiency and benefits to society, even without technical optimization of the firm itself. In addition, developing a closer relationship between a company and its regional system will facilitate the development of new optimization opportunities. Small coal-based CHP plants have lower-energy efficiency, higher environmental loading, and lower sustainability than large fossil fuel and renewable energy-based systems. The emergy exchange ratio (EER) proved to be an important index for evaluating the vitality of highly developed ecological-economic systems

  2. Solar cell concentrating system

    International Nuclear Information System (INIS)

    Garg, H.P.; Sharma, V.K.; Agarwal, R.K.

    1986-11-01

    This study reviews fabrication techniques and testing facilities for different solar cells under concentration which have been developed and tested. It is also aimed to examine solar energy concentrators which are prospective candidates for photovoltaic concentrator systems. This may provide an impetus to the scientists working in the area of solar cell technology

  3. Thermodynamic and thermoeconomic analysis of a system with biomass gasification, solid oxide fuel cell (SOFC) and Stirling engine

    International Nuclear Information System (INIS)

    Rokni, Masoud

    2014-01-01

    Thermodynamic and thermoeconomic investigations of a small-scale integrated gasification solid oxide fuel cell (SOFC) and Stirling engine for combined heat and power (CHP) with a net electric capacity of 120 kW e have been performed. Woodchips are used as gasification feedstock to produce syngas, which is then utilized to feed the anode side of the SOFC stacks. A thermal efficiency of 0.424 LHV (lower heating value) for the plant is found to use 89.4 kg/h of feedstock to produce the above mentioned electricity. Thermoeconomic analysis shows that the production price of electricity is 0.1204 $/kWh. Furthermore, hot water is considered as a by-product, and the cost of hot water is found to be 0.0214 $/kWh. When compared to other renewable systems of similar scales, this result shows that if both SOFC and Stirling engine technology enter the commercialization phase, then they can deliver electricity at a cost that is competitive with the corresponding renewable systems of the same size. - Highlights: • A 120 kW e integrated gasification SOFC–Stirling CHP is presented. • Effect of important parameters on plant characteristic and economy are studied. • A modest thermal efficiency of 0.41 is found after thermoeconomic optimization. • Reducing stack numbers cuts cost of electricity at expense of thermal efficiency. • The plant cost is estimated to be about 3433 $/kW when disposal costs are neglected

  4. Initial Market Assessment for Small-Scale Biomass-Based CHP

    Energy Technology Data Exchange (ETDEWEB)

    Brown, E.; Mann, M.

    2008-01-01

    The purpose of this report is to reexamine the energy generation market opportunities for biomass CHP applications smaller than 20 MW. This paper provides an overview of the benefits of and challenges for biomass CHP in terms of policy, including a discussion of the drivers behind, and constraints on, the biomass CHP market. The report provides a summary discussion of the available biomass supply types and technologies that could be used to feed the market. Two primary markets are outlined--rural/agricultural and urban--for small-scale biomass CHP, and illustrate the primary intersections of supply and demand for those markets. The paper concludes by summarizing the potential markets and suggests next steps for identifying and utilizing small-scale biomass.

  5. Experimental investigation of domestic micro-CHP based on the gas boiler fitted with ORC module

    Directory of Open Access Journals (Sweden)

    Wajs Jan

    2016-09-01

    Full Text Available The results of investigations conducted on the prototype of vapour driven micro-CHP unit integrated with a gas boiler are presented. The system enables cogeneration of heat and electric energy to cover the energy demand of a household. The idea of such system is to produce electricity for own demand or for selling it to the electric grid – in such situation the system user will became the prosumer. A typical commercial gas boiler, additionally equipped with an organic Rankine cycle (ORC module based on environmentally acceptable working fluid can be regarded as future generation unit. In the paper the prototype of innovative domestic cogenerative ORC system, consisting of a conventional gas boiler and a small size axial vapour microturbines (in-house designed for ORC and the commercially available for Rankine cycle (RC, evaporator and condenser were scrutinised. In the course of study the fluid working temperatures, rates of heat, electricity generation and efficiency of the whole system were obtained. The tested system could produce electricity in the amount of 1 kWe. Some preliminary tests were started with water as working fluid and the results for that case are also presented. The investigations showed that domestic gas boiler was able to provide the saturated/superheated ethanol vapour (in the ORC system and steam (in the RC system as working fluids.

  6. Optimal designs of small CHP plants in a market with fluctuating electricity prices

    DEFF Research Database (Denmark)

    Lund, Henrik; Andersen, A.N.

    2005-01-01

    The paper presents the Danish experince with methodologies and software tools, which have been used to design investment and operation strategies for almost all small CHP plants in Denmark during the decade of the triple tariff.......The paper presents the Danish experince with methodologies and software tools, which have been used to design investment and operation strategies for almost all small CHP plants in Denmark during the decade of the triple tariff....

  7. Policy schemes, operational strategies and system integration of residential co-generation fuel cells

    DEFF Research Database (Denmark)

    Hansen, Lise-Lotte Pade; Schröder, Sascha Thorsten; Münster, Marie

    2013-01-01

    a heat-driven strategy, with and without time-differentiated tariffs, and an electricity price driven strategy for the operation as a virtual power plant. The corresponding support schemes identified cover feed-in tariffs, net metering and feed-in premiums. Additionally, the interplay of the micro......CHP units with the national energy systems has been analysed. Our main findings are that net metering would be an appropriate tool to support FC based microCHP in Denmark, whereas a price premium would be the preferable tool in France and Portugal. Copyright © 2012, Hydrogen Energy Publications, LLC...

  8. Fuel cell systems

    International Nuclear Information System (INIS)

    Kotevski, Darko

    2003-01-01

    Fuel cell systems are an entirely different approach to the production of electricity than traditional technologies. They are similar to the batteries in that both produce direct current through electrochemical process. There are six types of fuel cells each with a different type of electrolyte, but they all share certain important characteristics: high electrical efficiency, low environmental impact and fuel flexibility. Fuel cells serve a variety of applications: stationary power plants, transport vehicles and portable power. That is why world wide efforts are addressed to improvement of this technology. (Original)

  9. Screening of CHP Potential at Federal Sites in Select Regions of the U.S.

    Energy Technology Data Exchange (ETDEWEB)

    Energy Nexus Group, . .

    2002-02-25

    Combined Cooling Heat and Power (CHP) is a master term for onsite power generation technologies that sequentially produce electrical or mechanical energy and useful thermal energy. Some form of CHP has existed for more than 100 years and it is now achieving a greater level of acceptance due to an increasing need for reliable power service and energy cost management. Capturing and using the heat produced as a byproduct of generating electricity from fuel sources increases the usable energy that can be obtained from the original fuel source. CHP technologies have the potential to reduce energy consumption through increased efficiency--decreasing energy bills as well as pollution. The EPA recognizes CHP as a potent climate change mitigation measure. The U.S. Department of Energy (D.O.E.) Federal Energy Management Program (FEMP) is assisting Federal agencies to realize their energy efficiency goals. CHP is an efficiency measure that is receiving growing attention because of its sizable potential to provide efficiency, environmental, and reliability benefits. CHP therefore benefits the host facility, the electric infrastructure, and the U.S. society as a whole. This report and study seeks to make a preliminary inquiry into near term CHP opportunities for federal facilities in selected U.S. regions. It offers to help focus the attention of policy makers and energy facility managers on good candidate facilities for CHP. First, a ranked list of high potential individual sites is identified. Then, several classes of federal facilities are identified for the multiple opportunities they offer as a class. Recommendations are then offered for appropriate next steps for the evaluation and cost effective implementation of CHP. This study was designed to ultimately rank federal facilities in terms of their potential to take advantage of CHP economic and external savings in the near term. In order to best serve the purposes of this study, projections have been expressed in terms of

  10. Energy conservation in methanol plant using CHP system

    International Nuclear Information System (INIS)

    Azadi, Marjan; Tahouni, Nassim; Panjeshahi, M. Hassan

    2016-01-01

    Highlights: • Feasibility of turbo expander integration with an industrial plant was studied. • Combined pinch-exergy analysis was used to achieve optimum performance of process. • Generation of power led to profitability of gas turbine integrated plant. - Abstract: Today, the efficient use of energy is a significant critical issue in various industries such as petrochemical industries. Hence, it seems essential to apply proper strategies to reduce energy consumption in such processes. A methanol production plant at a live Petrochemical Complex was selected as the case study in this research. The plant was first evaluated with combined pinch and exergy analysis from exergetic dissipation point of view. Owing to high temperature and pressure of reactor outlet stream, methanol synthesis reactor products contain considerable content of exergy. For the purpose of the present survey, the available content of exergy was used for power production by integrating a turbine expander with methanol reactor product. Utilization of reactor product’s high pressure in turbine reduces the temperature of turbine outlet stream to levels lower than those required for heating demands of existing streams in methanol synthesis cycle. Therefore, to keep the stream thermally balanced, the required hot utility of the process is increased and to compensate this increase, the heat exchanger network of the process was retrofitted based on pinch analysis concepts. The results showed that in gas turbine integrated scheme, approximately a net power of 7.5 MW is produced. Also, the total investment of turbine, compressor and heat exchangers area equals to 18.2 × 10 6 US$, and the annual saving value is about 6.1 × 10 6 US$/y. Based on economic data, payback period is estimated to be 3 years.

  11. Investigation of the prospect of energy self-sufficiency and technical performance of an integrated PEMFC (proton exchange membrane fuel cell), dairy farm and biogas plant system

    International Nuclear Information System (INIS)

    Guan, Tingting; Alvfors, Per; Lindbergh, Göran

    2014-01-01

    Highlights: • A PEMFC stack with a 40% of electrical efficiency will make the integrated PEMFC-CHP, biogas plant and dairy farm self-sufficient. • The quality of the reformate gas is good enough to support normal operation of the PEMFC-CHP. • The methane conversion rate and the content of the CH 4 in the biogas need to be balanced in order to obtain the best system performance. • Compared with a coal-fired CHP plant, the integrated system can avoid coal consumption and CO 2 emissions. - Abstract: A PEMFC fuelled with hydrogen is known for its high efficiency and low local emissions. However, the generation of hydrogen is always a controversial issue for the application of the PEMFC due to the use of fossil fuel and the possible carbon dioxide emissions. Presently, the PEMFC-CHP fed with renewable fuels, such as biogas, appears to be the most attractive energy converter–fuel combination. In this paper, an integrated PEMFC-CHP, a dairy farm and a biogas plant are studied. A PEMFC-CHP fed with reformate gas from the biogas plant generates electricity and heat to a dairy farm and a biogas plant, while the dairy farm delivers wet manure to the biogas plant as the feedstock for biogas production. This integrated system has been modelled for steady-state conditions by using Aspen Plus®. The results indicate that the wet manure production of a dairy farm with 300 milked cows can support a biogas plant to give 1280 MW h of biogas annually. Based on the biogas production, a PEMFC-CHP with a stack having an electrical efficiency of 40% generates 360 MW h electricity and 680 MW h heat per year, which is enough to cover the energy demand of the whole system while the total efficiency of the PEMFC-CHP system is 82%. The integrated PEMFC-CHP, dairy farm and biogas plant could make the dairy farm and the biogas plant self-sufficient in a sustainable way provided the PEMFC-CHP has the electrical efficiency stated above. The effect of the methane conversion rate and the

  12. New CHP plant for a rubber products manufacturer; Nueva planta e cogeneración para un fabricante de productos de hule

    Energy Technology Data Exchange (ETDEWEB)

    Vila, R.; Martí, C.

    2016-07-01

    At the end of 2014 the company Industrias de Hule Galgo decided to undertake the installation project of an efficient CHP plant for its production plant, with the aim of bringing down energy costs and improving the company’s competitive position in the market. The new plant has already started its first operational phase. The project has comprised the installation of a single cycle with gas-powered gensets providing a total electrical capacity of 6.6 MW. This provides the necessary thermal oil for the production plant; covers 100% of the electrical power consumed by the industrial complex; and also generates cooling water, giving improved production capacity by supercooling the extrusion system. To execute these works, Industrias de Hule Galgo contracted the services of engineering company AESA to provide the engineering, procurement and construction of the CHP plant. (Author)

  13. Management of fluctuations in wind power and CHP comparing two possible Danish strategies

    International Nuclear Information System (INIS)

    Lund, H.; Clark, W.W.

    2002-01-01

    Both CHP (combined heat and power production) and wind power are important elements of Danish energy policy. Today, approximately 50% of both the Danish electricity and heat demand are produced in CHP and more than 15% of the electricity demand is produced by wind turbines. Both technologies are essential for the implementation of Danish climate change response objectives, and both technologies are intended for further expansion in the coming decade. Meanwhile, the integration of CHP and wind power is subject to fluctuations in electricity production. Wind turbines depend on the wind, and CHP depends on the heat demand. This article discusses and analyses two different national strategies for solving this problem. One strategy, which is the current official government policy known as the export strategy, proposes to take advantage of the Nordic and European markets for selling and buying electricity. In this case, surplus electricity from wind power and CHP simply will be sold to neighbouring countries. Another strategy, the self-supply strategy, runs the CHP units to meet both demand and the fluctuations in the wind scheduling. In this case, investments in heat storages are necessary and heat pumps have to be added to the CHP units. Based on official Danish energy policy and energy plans, this article quantifies the problem for the year 2015 in terms of the amount of surplus electricity, and investments in heat pumps, etc. needed to solve the problem are calculated. Based on these results between the two different strategies, the conclusion is that the self-supply strategy is recommended over the official export strategy. (author)

  14. Generic Combined Heat and Power (CHP Model for the Concept Phase of Energy Planning Process

    Directory of Open Access Journals (Sweden)

    Satya Gopisetty

    2016-12-01

    Full Text Available Micro gas turbines (MGTs are regarded as combined heat and power (CHP units which offer high fuel utilization and low emissions. They are applied in decentralized energy generation. To facilitate the planning process of energy systems, namely in the context of the increasing application of optimization techniques, there is a need for easy-to-parametrize component models with sufficient accuracy which allow a fast computation. In this paper, a model is proposed where the non-linear part load characteristics of the MGT are linearized by means of physical insight of the working principles of turbomachinery. Further, it is shown that the model can be parametrized by the data usually available in spec sheets. With this model a uniform description of MGTs from several manufacturers covering an electrical power range from 30 k W to 333 k W can be obtained. The MGT model was implemented by means of Modelica/Dymola. The resulting MGT system model, comprising further heat exchangers and hydraulic components, was validated using the experimental data of a 65 k W MGT from a trigeneration energy system.

  15. The Added Economic and Environmental Value of Solar Thermal Systems in Microgrids with CombinedHeat and Power

    Energy Technology Data Exchange (ETDEWEB)

    Marnay, Chris; Stadler, Michael; Cardoso, Goncalo; Megel, Olivier; Lai, Judy; Siddiqui, Afzal

    2009-08-15

    The addition of solar thermal and heat storage systems can improve the economic, as well as environmental attraction of micro-generation systems, e.g. fuel cells with or without combined heat and power (CHP) and contribute to enhanced CO2 reduction. However, the interactions between solar thermal collection and storage systems and CHP systems can be complex, depending on the tariff structure, load profile, etc. In order to examine the impact of solar thermal and heat storage on CO2 emissions and annual energy costs, a microgrid's distributed energy resources (DER) adoption problem is formulated as a mixed-integer linear program. The objective is minimization of annual energy costs. This paper focuses on analysis of the optimal interaction of solar thermal systems, which can be used for domestic hot water, space heating and/or cooling, and micro-CHP systems in the California service territory of San Diego Gas and Electric (SDG&E). Contrary to typical expectations, our results indicate that despite the high solar radiation in southern California, fossil based CHP units are dominant, even with forecast 2020 technology and costs. A CO2 pricing scheme would be needed to incent installation of combined solar thermal absorption chiller systems, and no heat storage systems are adopted. This research also shows that photovoltaic (PV) arrays are favored by CO2 pricing more than solar thermal adoption.

  16. The Added Economic and Environmental Value of Solar Thermal Systems in Microgrids with CombinedHeat and Power

    International Nuclear Information System (INIS)

    Marnay, Chris; Stadler, Michael; Cardoso, Goncalo; Megel, Olivier; Lai, Judy; Siddiqui, Afzal

    2009-01-01

    The addition of solar thermal and heat storage systems can improve the economic, as well as environmental attraction of micro-generation systems, e.g. fuel cells with or without combined heat and power (CHP) and contribute to enhanced CO2 reduction. However, the interactions between solar thermal collection and storage systems and CHP systems can be complex, depending on the tariff structure, load profile, etc. In order to examine the impact of solar thermal and heat storage on CO2 emissions and annual energy costs, a microgrid's distributed energy resources (DER) adoption problem is formulated as a mixed-integer linear program. The objective is minimization of annual energy costs. This paper focuses on analysis of the optimal interaction of solar thermal systems, which can be used for domestic hot water, space heating and/or cooling, and micro-CHP systems in the California service territory of San Diego Gas and Electric (SDG and amp;E). Contrary to typical expectations, our results indicate that despite the high solar radiation in southern California, fossil based CHP units are dominant, even with forecast 2020 technology and costs. A CO2 pricing scheme would be needed to incent installation of combined solar thermal absorption chiller systems, and no heat storage systems are adopted. This research also shows that photovoltaic (PV) arrays are favored by CO2 pricing more than solar thermal adoption.

  17. Analysis of a CHP plant in a municipal solid waste landfill in the South of Spain

    International Nuclear Information System (INIS)

    Chacartegui, Ricardo; Carvalho, Monica; Abrahão, Raphael; Becerra, José

    2015-01-01

    The most effective strategy to manage and treat solid urban residues, with the least environmental impact as well as lowest economic and energy costs, is a challenge for sustainability in current society, who actually pay for the final management of these residues. This manuscript analyzes the potential of biogas generation in an urban solid residue treatment plant, and the potential use for cogeneration in situ at the landfill. The objective is to identify the energy potential associated with the landfill and its potential use to accelerate the evaporation of leachate through the supply of heat, reducing the risks of exceeding the collection capacity of the leachate ponds. The change in legislation for generation within the special regime in Spain (2014) introduced a sudden change in the direction of energy policies, which affected significantly the profitability of these facilities. This manuscript analyzes the application of both legislations, previous (2007) and current (2014), for the case of a cogeneration system installed in this landfill. The results obtained indicate that even with a much more restrictive legislation in force, acceptable values are obtained for the evaluation of the investment – however, better results were obtained for the previous legislation that favored the special regime. The new regulation constrains the maximum and minimum annual operating hours for landfill cogeneration. It results in relevant periods with limited use of biogas for electricity generation. Biogas storage for delayed future consumption in the same installation and biogas selling for external use in boilers are proposed as options for this biogas in excess. They can reduce greenhouse gases emissions from the non-used biogas and can improve the economic results of the facility. - Highlights: • Analysis of biogas generation capacity in an existing landfill at South of Spain. • Analysis of the integration of gas engine for cogeneration. • CHP integration for

  18. Energy Management for Community Energy Network with CHP Based on Cooperative Game

    Directory of Open Access Journals (Sweden)

    Xiaofeng Liu

    2018-04-01

    Full Text Available Integrated energy system (IES has received increasing attention in micro grid due to the high energy efficiency and low emission of carbon dioxide. Based on the technology of combined heat and power (CHP, this paper develops a novel operation mechanism with community micro turbine and shared energy storage system (ESS for energy management of prosumers. In the proposed framework, micro-grid operator (MGO equipped with micro turbine and ESS provides energy selling business and ESS leasing business for prosumers. Prosumers can make energy trading with public grid and MGO, and ESS will be shared among prosumers when they pay for the rent to MGO. Based on such framework, we adopt a cooperative game for prosumers to determine optimal energy trading strategies from MGO and public grid for the next day. Concretely, a cooperative game model is formulated to search the optimal strategies aiming at minimizing the daily cost of coalition, and then a bilateral Shapley value (BSV is proposed to solve the allocation problem of coalition’s cost among prosumers. To verify the effectiveness of proposed energy management framework, a practical example is conducted with a community energy network containing MGO and 10 residential buildings. Simulation results show that the proposed scheme is able to provide financial benefits to all prosumers, while providing peak load leveling for the grid.

  19. Contribution of wind power and CHP to exports from Western Denmark during 2000-2004

    International Nuclear Information System (INIS)

    Mignard, D.; Harrison, G.P.; Pritchard, C.L.

    2007-01-01

    The experience of Denmark is used by the United Kingdom's anti-wind lobby to demonstrate that intermittency and inaccuracies in wind forecasting make wind power ineffective and expensive. A further assertion is that most of the power is 'unwanted' since up to 80% of it is exported. Here, available data for Danish energy production for 2000-2004 is used to assess the link between wind generation and exports and test the validity of these claims. Net exports in Western Denmark showed good correlation with wind production. However, they were more significantly correlated with the production from local combined heat and power (CHP) plants. In order to test the 80% export claim, a simple technique was devised to correlate and rank hourly net exports and generation from wind and local CHP. In the case where net exports were primarily attributed to (or blamed on) wind, 44-84% of annual wind production was deemed to be exported, with wind 'causing' 57-79% of net annual exports. For this extreme scenario, the percentage values are in line with those of critics. However, under the opposite extreme scenario in which exports are attributed to local CHP, 77-94% of exports were caused by CHP and only 4-32% of wind production was exported. Overall, this study shows that there is some degree of correlation between net exports and wind power, but that the claim that 80% is exported is unwarranted since it ignores the demonstrably stronger influence of local CHP. (author)

  20. Fuel cell system with interconnect

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Zhien; Goettler, Richard

    2016-12-20

    The present invention includes an integrated planar, series connected fuel cell system having electrochemical cells electrically connected via interconnects, wherein the anodes of the electrochemical cells are protected against Ni loss and migration via an engineered porous anode barrier layer.

  1. Clinical review of supracricoid laryngectomy with CHEP and CHP. 50 patients treated in 11 years

    International Nuclear Information System (INIS)

    Nakayama, Meijin; Seino, Yutomo; Hayashi, Seiichi; Miyamoto, Shunsuke; Takeda, Masahiko; Masaki, Takashi; Yokobori, Satoru; Okamoto, Makito

    2009-01-01

    An analysis of clinical data on 50 patients undergoing supracricoid laryngectomy (SCL) between 1997 and 2008 id est (i.e.), cricohyoidoepiglottopexy (CHEP) in 47 and cricohyoidopexy (CHP) in 3 cases showed that the number of SCL cases operated on within a year surpassed that of Total Laryngectomy after 2003. Selection criteria included performance status 0-1 and blood gas PO2>80 torr, especially in those patients over 70 years old. Postoperative wound infection occurred in 16 patients (32%), with four requiring additional surgical intervention (two ruptured pexis and two chondritis induced by C3-C4 osteophytes). A history of radiotherapy and systemic complications, i.e., diabetes and renal failure, added to the risk of wound infection. Introducing a clinical pathway shortened hospitalization. Vocal function was achieved in 96% and swallowing function in 89% of patients. Five-year crude survival in CHEP was 69% and in total laryngectomy (TL) 51%. Laryngeal preservation was 70%, increasing to 89% after the introduction of SCL. SCL-CHEP is thus indicated for unfavorable T2 (ASCO 2006), well-selected T3, T4, and rT1-4 (radiation failures). Effort should emphasize a good balance in prognosis and function in organ preservation for laryngeal cancer. (author)

  2. Investment appraisal for small CHP technology in biomass-fuel power plant

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-07-01

    The paper is essentially an investment appraisal for small CHP (combined heat and power) technology in biomass-fuel power plant and discusses and presents data on the combustion/steam cycle technologies to demonstrate the economic viability of CHP projects using established market costs for technology and employing energy crops as biomass fuel. The data is based on the UK, where electricity prices are low, but the overseas market (where prices are higher and there is potential for UK exports) is also discussed. The report aims to synthesise up-to-date technical and economic information on biomass-fuel CHP projects of small scale and focuses on technical and financial information on equipment, capital, construction and operating costs, and revenue streams.

  3. The scale of transition: an integrated study of the performance of CHP biomass plants in the Netherlands

    NARCIS (Netherlands)

    Proka, A.; Hisschemoller, M.; Papyrakis, E.

    2014-01-01

    Combined heat and power (CHP) plants using biomass are considered important to substantially increase the share of renewables in the total energy supply and meet ambitious climate targets. The analysis focuses on the links between the size of bio-fuelled CHP plants and their techno-economic and

  4. ECONOMIC ASPECTS OF DESIGNING, CONSTRUCTION AND OPERATION OF MINI-CHP IN BELARUS

    Directory of Open Access Journals (Sweden)

    Kovalev I.L.

    2013-08-01

    Full Text Available The article raised questions of efficiency of operation of CHP in industrial enterprises in Belarus, as well as the problem of cross-subsidies in the energy sector of the Republic and its negative impact on the economy as a whole. Data of the electricity tariffs for households and industrial consumers in Belarus and the countries the EU have been presented and analyzed. Main economic indicators and results of operation of a number of mini–CHP, which were built in Belarus over the last ten years, have been analyzed. The operating results have been compared with a view to economic efficiency of all investigated local energy facilities.

  5. Thermodynamic and thermoeconomic analysis of a system with biomass gasification, solid oxide fuel cell (SOFC) and Stirling engine

    DEFF Research Database (Denmark)

    Rokni, Masoud

    2014-01-01

    Thermodynamic and thermoeconomic investigations of a small-scale integrated gasification solid oxide fuel cell (SOFC) and Stirling engine for combined heat and power (CHP) with a net electric capacity of 120kWe have been performed. Woodchips are used as gasification feedstock to produce syngas...

  6. Coordination of decentralised CHP units for a grid-oriented operation mode; Koordination dezentraler Kraft-Waerme-Kopplungsanlagen fuer die Verwendung einer netzorientierten Betriebsweise im Verbund

    Energy Technology Data Exchange (ETDEWEB)

    Korte, M. [Oldenburg Univ. (Germany). Dept. fuer Informatik; Troeschel, M. [OFFIS e.V., Oldenburg (Germany). Betriebliches Informationsmanagement; Schulz, C.; Pielke, M.; Kurrat, M. [Technische Univ. Braunschweig (Germany). Inst. fuer Hochspannungstechnnk und Elektrische Energieanlagen; Slomka, F. [Ulm Univ. (Germany). Inst. fuer Eingebettete Systeme/Echtzeitsysteme

    2007-07-01

    Decentralised combined heat and power micro-units are considered as an interesting option to reduce the primary energy need and thus the carbon dioxide emissions of buildings. The technology of simultaneous generation of usable heat and electrical power is already available through combustion engine CHPs. In the next years fuel cell CHPs will be added. Due to the current energy price development a rising number of CHP micro-units in the mains electricity grid is expected. Thus for the power supplier the questions, which strategies are used in order to be able to integrate them technically into the grid and economically into the business field, become ever more important. (orig.)

  7. Animal Cell Expression Systems.

    Science.gov (United States)

    Butler, M; Reichl, U

    2017-10-03

    control. Over the past decade, however, there have been various commercial influenza vaccines made available from cell technology using animal host cells. Analysis of glycosylation control shows that the type of host cell has the greatest influence on the final analyzed glycan profile. Other factors such as the virus strain, the cultivation system, or various process parameters have been shown to have only a minor effect on the glycosylation pattern. We predict that the analysis of glycan profiles in viral vaccines will become increasingly important in the development and consistent manufacturing of safe and potent vaccines. Graphical Abstract.

  8. EFFICIENCY OF THE USE OF HEAT PUMPS ON THE CHP PLANTS

    Directory of Open Access Journals (Sweden)

    Juravleov A.A.

    2007-04-01

    Full Text Available The work is dedicated to the calculus of the efficiency of the use of heat pumps on the CHP plants. There are presented the interdependences between the pay-back period and NPV of heat pump and the price of 1 kWt of thermal power of heat pump and of the tariff of electricity.

  9. Load control in low voltage level of the electricity grid using µCHP appliances

    NARCIS (Netherlands)

    Bosman, M.G.C.; Bakker, Vincent; Molderink, Albert; Hurink, Johann L.; Smit, Gerardus Johannes Maria

    2008-01-01

    The introduction of microCHP (Combined Heat and Power) appliances and other means of distributed generation causes a shift in the way electricity is produced and consumed. Households themselves produce electricity and deliver the surplus to the grid. In this way, the distributed generation also has

  10. A Compound Herbal Preparation (CHP) in the Treatment of Children with ADHD: A Randomized Controlled Trial

    Science.gov (United States)

    Katz, M.; Adar Levine, A.; Kol-Degani, H.; Kav-Venaki, L.

    2010-01-01

    Objective: Evaluation of the efficacy of a patented, compound herbal preparation (CHP) in improving attention, cognition, and impulse control in children with ADHD. Method: Design: A randomized, double-blind, placebo-controlled trial. Setting: University-affiliated tertiary medical center. Participants: 120 children newly diagnosed with ADHD,…

  11. Increased electrical efficiency in biofueled CHP plants by biomass drying; Oekat elutbyte i biobraensleeldade kraftvaermeanlaeggningar med hjaelp av foertorkning

    Energy Technology Data Exchange (ETDEWEB)

    Berntsson, Mikael; Thorson, Ola; Wennberg, Olle

    2010-09-15

    In this report, integrated biofuel drying has been studied for two cases. One is the existing CHP plant at ENA Energi AB in Enkoeping and the other is a theoretical case. The thought plant is assumed to have a steam generating performance that is probable for a future CHP plant optimised for power production. The CHP plant at ENA Energi with its integrated bed drying system has been used as a model in this study. The plant has a grate fired boiler with the capacity to co-produce 24 MW electricity and 55 MW heat. It is designed to use biofuel with moisture content between 40 and 55 %. However, the boiler is able to manage even dryer fuels with the moisture content of about 35 % without complications. Since the boiler operates on part load during most of the season, there are free capacity which can be used for delivering heat to the drying system. The increased power production is a result of mainly two factors: Increased demand of heat as the dryer uses district heating and thus improved possibility to produce steam; and, The season of operation can be extended, since the point where the minimum load of the boiler occurs can be pushed forward as a result of increased demand of heat. For future CHP plants, an optimised plant has been used as a model. The steam data is assumed to be 170 bar and 540 deg C with reheating. For this plant, both on-site and offsite drying have been studied. The case study comprises a whole season of operation and the fuel is assumed to be dried from 50 to 10 %. The size of the optimised plant is as to fit the dimension of a main production unit in a district heating net equal to the tenth largest in Sweden. Heat delivery is assumed to be 896 GWh/year and the maximum heat delivery of district heating is 250 MW. The sizing of the boiler is made to maximise the production of electricity, and thus dependent of the drying strategy used. Flue gas condensation is assumed to be used as much as possible. It decreases the basis for power production

  12. Support schemes and ownership structures - The policy context for fuel cell based micro-combined heat and power

    Energy Technology Data Exchange (ETDEWEB)

    Ropenus, S.; Thorsten Schroeder, S.; Costa, A.; Obe, E.

    2010-05-15

    In recent years, fuel cell based micro-combined heat and power has received increasing attention due to its potential contribution to energy savings, efficiency gains, customer proximity and flexibility in operation and capacity size. The FC4Home project assesses technical and economic aspects of the ongoing fuel cell based micro-combined heat and power (mCHP) demonstration projects by addressing the socio-economic and systems analyses perspectives of a large-scale promotion scheme of fuel cells. This document constitutes the deliverable of Work Package 1 of the FC4Home project and provides an introduction to the policy context for mCHP. Section 1 describes the rationale for the promotion of mCHP by explaining its potential contribution to European energy policy goals. Section 2 addresses the policy context at the supranational European level by outlining relevant EU Directives on support schemes for promoting combined heat and power and energy from renewable sources. These Directives are to be implemented at the national level by the Member States. Section 3 conceptually presents the spectrum of national support schemes, ranging from investment support to market-based operational support. The choice of support scheme simultaneously affects risk and technological development, which is the focus of Section 4. Subsequent to this conceptual overview, Section 5 takes a glance at the national application of support schemes for mCHP in practice, notably in the three country cases of the FC4Home project, Denmark, France and Portugal. Another crucial aspect for the diffusion of the mCHP technology is possible ownership structures. These may range from full consumer ownership to ownership by utilities and energy service companies, which is discussed in Section 6. Finally, a conclusion (Section 7) wraps up previous findings and provides a short 'preview' of the quantitative analyses in subsequent Work Packages by giving some food for thought on the way. (author)

  13. Fuel cell system with interconnect

    Energy Technology Data Exchange (ETDEWEB)

    Goettler, Richard; Liu, Zhien

    2017-12-12

    The present invention includes a fuel cell system having a plurality of adjacent electrochemical cells formed of an anode layer, a cathode layer spaced apart from the anode layer, and an electrolyte layer disposed between the anode layer and the cathode layer. The fuel cell system also includes at least one interconnect, the interconnect being structured to conduct free electrons between adjacent electrochemical cells. Each interconnect includes a primary conductor embedded within the electrolyte layer and structured to conduct the free electrons.

  14. Systems biomechanics of the cell

    CERN Document Server

    Maly, Ivan V

    2013-01-01

    Systems Biomechanics of the Cell attempts to outline systems biomechanics of the cell as an emergent and promising discipline. The new field owes conceptually to cell mechanics, organism-level systems biomechanics, and biology of biochemical systems. Its distinct methodology is to elucidate the structure and behavior of the cell by analyzing the unintuitive collective effects of elementary physical forces that interact within the heritable cellular framework. The problematics amenable to this approach includes the variety of cellular activities that involve the form and movement of the cell body and boundary (nucleus, centrosome, microtubules, cortex, and membrane). Among the elementary system effects in the biomechanics of the cell, instability of symmetry, emergent irreversibility, and multiperiodic dissipative motion can be noted. Research results from recent journal articles are placed in this unifying framework. It is suggested that the emergent discipline has the potential to expand the spectrum of ques...

  15. Proton exchange membrane fuel cell for cooperating households: A convenient combined heat and power solution for residential applications

    International Nuclear Information System (INIS)

    Cappa, Francesco; Facci, Andrea Luigi; Ubertini, Stefano

    2015-01-01

    In this paper we compare the technical and economical performances of a high temperature proton exchange membrane fuel cell with those of an internal combustion engine for a 10 kW combined heat and power residential application. In a view of social innovation, this solution will create new partnerships of cooperating families aiming to reduce the energy consumption and costs. The energy system is simulated through a lumped model. We compare, in the Italian context, the total daily operating cost and energy savings of each system with respect to the separate purchase of electricity from the grid and production of the thermal energy through a standard boiler. The analysis is carried out with the energy systems operating with both the standard thermal tracking and an optimized management. The latter is retrieved through an optimization methodology based on the graph theory. We show that the internal combustion engine is much more affected by the choice of the operating strategy with respect to the fuel cell, in terms long term profitability. Then we conduct a net present value analysis with the aim of evidencing the convenience of using a high temperature proton exchange membrane fuel cell for cogeneration in residential applications. - Highlights: • Fuel cells are a feasible and economically convenient solution for residential CHP. • Control strategy is fundamental for the economical performance of a residential CHP. • Flexibility is a major strength of the fuel cell CHP.

  16. Large stationary fuel cell systems: Status and dynamic requirements

    Science.gov (United States)

    Bischoff, Manfred

    Molten carbonate fuel cell demonstrations to-date, have been able to show the highest fuel-to-electricity conversion efficiencies (>50%) of any stand-alone fuel cell type. The primary developer of this type of fuel cell in United States is Fuel Cell Energy Corporation (FCE), the developer and manufacturer of the Direct FuelCell ™ concept. FCE and MTU CFC Solutions in Germany, a licensee of FCE have demonstrated carbonate fuel cells from 10 kW to 2 MW of electrical output on a variety of fuels. IHI in Japan are also developing carbonate fuel cells for stationary power and have recently successfully demonstrated the technology in Kawagoe, Japan. In Italy, Ansaldo fuel cell have demonstrated a 100 kW carbonate fuel cell in Milan. In Korea, the Ministry of Commerce, Industry and Energy has committed to install 300 fuel cell units, sized 250 kW to 1 MW, for distributed power generation by 2012. Carbonate fuel cell technology is more fuel flexible than lower temperature fuel cell technologies and is well suited for on-site stationary CHP applications as well as to marine, military, and traction applications. The present paper gives an overview about the commercialisation efforts for the molten carbonate fuel cell technology.

  17. High Affinity Binding of Chp1 Chromodomain to K9 Methylated Histone H3 is Required to Establish Centromeric Hterochromatin

    Energy Technology Data Exchange (ETDEWEB)

    Schalch, T.; Job, G; Noffsinger, V; Shanker, S; Kuscu, C; Joshua-Tor, L; Partridge, J

    2009-01-01

    In fission yeast, assembly of centromeric heterochromatin requires the RITS complex, which consists of Ago1, Tas3, Chp1, and siRNAs derived from centromeric repeats. Recruitment of RITS to centromeres has been proposed to depend on siRNA-dependent targeting of Ago1 to centromeric sequences. Previously, we demonstrated that methylated lysine 9 of histone H3 (H3K9me) acts upstream of siRNAs during heterochromatin establishment. Our crystal structure of Chp1's chromodomain in complex with a trimethylated lysine 9 H3 peptide reveals extensive sites of contact that contribute to Chp1's high-affinity binding. We found that this high-affinity binding is critical for the efficient establishment of centromeric heterochromatin, but preassembled heterochromatin can be maintained when Chp1's affinity for H3K9me is greatly reduced.

  18. Anti-diabetic effect of Cyclo-His-Pro (CHP)-enriched yeast ...

    African Journals Online (AJOL)

    The present study was designed to investigate the hypoglycemic effects of the daily oral dose of 0.50 to 0.75 g/kg of yeast hydrolysate (YH) containing high Cyclo-His-Pro (51.0 mg CHP/g YH) on normal and streptozotocin (STZ)-induced diabetic rats for 14 days. In STZ-induced diabetic rats, after administrations of the YH for ...

  19. Multi-Objective Analysis of a CHP Plant Integrated Microgrid in Pakistan

    Directory of Open Access Journals (Sweden)

    Asad Waqar

    2017-10-01

    Full Text Available In developing countries like Pakistan, the capacity shortage (CS of electricity is a critical problem. The frequent natural gas (NG outages compel consumers to use electricity to fulfill the thermal loads, which ends up as an increase in electrical load. In this scenario, the authors have proposed the concept of a combined heat & power (CHP plant to be a better option for supplying both electrical and thermal loads simultaneously. A CHP plant-based microgrid comprising a PV array, diesel generators and batteries (operating in grid-connected as well as islanded modes has been simulated using the HOMER Pro software. Different configurations of distributed generators (DGs with/without batteries have been evaluated considering multiple objectives. The multiple objectives include the minimization of the total net present cost (TNPC, cost of generated energy (COE and the annual greenhouse gas (GHG emissions, as well as the maximization of annual waste heat recovery (WHR of thermal units and annual grid sales (GS. These objectives are subject to the constraints of power balance, battery operation within state of charge (SOC limits, generator operation within capacity limits and zero capacity shortage. The simulations have been performed on six cities including Islamabad, Lahore, Karachi, Peshawar, Quetta and Gilgit. The simulation results have been analyzed to find the most optimal city for the CHP plant integrated microgrid.

  20. Optimum steam data in bio-fuelled CHP; Optimala aangdata foer biobraensleeldade kraftvaermeverk

    Energy Technology Data Exchange (ETDEWEB)

    Steinwall, Pontus; Johansson, Kent; Svensson, Sven-Aake [Sycon Energikonsult AB, Malmoe (Sweden); Adolfson, Helene; Ekelund, Niclas [EPS Consulting AB, Vaenersborg (Sweden)

    2002-04-01

    This report deals with which steam data that gives the lowest electricity production cost in a biofuelled CHP. Three different sizes of CHP have been examined with a CFB of 30, 75 and 120 MWth. Calculations have been made to find how the investment cost depends on the steam data. The need of components, material and working time to build the boilers has been examined to find these costs. The costs for operation and maintenance are also affected by the steam data, especially the cost for high temperature corrosion at the superheaters. By data from other projects at Vaermeforsk the endurance of the superheaters has been estimated. The cost for manufacturing and changing the superheaters has been calculated with knowledge from projects carried through. The maintenance costs for the superheaters in are exponential to the steam data but rather proportional to the plant size at the same steam data. The steam data that is preferable has been examined by calculating the power production cost. The income from district heat is very important for the result why this is varied. The fuel price is 110 SEK/MWh but doesn't affect the result. Our conclusion is that in a CHP, credited with normal levels for the DH, should the steam temperature be under 500 deg C. The admission data should PN 160 or lower. High steam data are most interesting at low levels of the income from DH.

  1. H2NG (hydrogen-natural gas mixtures) effects on energy performances of a condensing micro-CHP (combined heat and power) for residential applications: An expeditious assessment of water condensation and experimental analysis

    International Nuclear Information System (INIS)

    Lo Basso, Gianluigi; Santoli, Livio de; Albo, Angelo; Nastasi, Benedetto

    2015-01-01

    In order to accomplish significant primary energy saving and GHG (greenhouse gas) emissions reduction, CHP (combined heat and power) technology can be adopted largely for industrial and civil sectors. Waiting for the cutting-edge appliances (i.e. Fuel Cell) wide deployment, ICEs (internal combustion engines) fuelled with an environmentally-friendly fuel, such as H 2 NG (hydrogen-natural gas mixtures) could represent the bridge technology towards the forthcoming pure hydrogen economy. This paper deals with the results of an experimental campaign carried out on a Single Cylinder ICE, fuelled with NG (natural gas) and H 2 NG @ 15% vol. In detail, energy performances were assessed at rated and partial loads. From data analysis, it emerged that the electrical efficiency increased up to 2.28%, at the expense of the heat recovery one, having added hydrogen. Additionally, due to the higher water content in exhaust gas when H 2 NG is burned, it was investigated on how heat recovery efficiency has been affected by condensing operating conditions. Finally, to estimate this benefit, an expeditious procedure was developed building three maps for H 2 NG blends condensing properties from 0% up to 30% vol. of H 2 . Their outputs provided the condensation efficiency value and the absolute gain of heat recovery one with varying exhaust gas temperatures and hydrogen fraction in the mixture. - Highlights: • H 2 NG mixture effects on a commercial technology μCHP for residential applications. • Experimental analysis and methodology for H 2 NG condensing properties assessment. • CO 2 specific emissions calculation accounting for electrical and thermal outputs. • Uncertainty analysis on the μCHP energy performances and methodology validation. • H 2 addition coupling a condensing heat exchanger enhance CHP First Law efficiency

  2. Ambient pressure fuel cell system

    Science.gov (United States)

    Wilson, Mahlon S.

    2000-01-01

    An ambient pressure fuel cell system is provided with a fuel cell stack formed from a plurality of fuel cells having membrane/electrode assemblies (MEAs) that are hydrated with liquid water and bipolar plates with anode and cathode sides for distributing hydrogen fuel gas and water to a first side of each one of the MEAs and air with reactant oxygen gas to a second side of each one of the MEAs. A pump supplies liquid water to the fuel cells. A recirculating system may be used to return unused hydrogen fuel gas to the stack. A near-ambient pressure blower blows air through the fuel cell stack in excess of reaction stoichiometric amounts to react with the hydrogen fuel gas.

  3. Environmental burdens over the entire life cycle of a biomass CHP plant

    International Nuclear Information System (INIS)

    Jungmeier, G.; Spitzer, J.; Resch, G.

    1998-01-01

    To increase the use of biomass for energy production it is important to know the possible and significant environmental effects. A life cycle inventory (LCI) was made on a 1.3 MW el biomass CHP plant located in Reuthe/Vorarlberg/Austria with the purpose of analysing the different environmental burdens over the entire life cycle. The plant is fired with coarse and small fuelwood (10,000 t/yr) from industrial waste and forest residues. The boiler for the steam process has a moving grate burner and a muffle burner. The annual production is 4700 MWh of electricity and 29,000 MWh of district heat. The methodology of the analysis is orientated on the ISO Committee Draft of the Series 13,600. The analysis was carried out for the different sections of the biomass plant over their entire life cycle-construction (1 yr), operation (20 yrs) and dismantling (1 yr). The plant in Reuthe, which is the first cogeneration system of this kind in Austria, is a model for other similar projects. The results are shown as environmental burdens of one year and of the entire life cycle. Some results of the life cycle inventory, like the mass and energy balances, selected emissions to air, allocation results and effects on carbon storage pools are given. The results demonstrate that depending on the stage and the period of life, different environmental burdens become significant, i.e. CO 2 emissions of fossil fuels during construction. NO x emission during operation, emissions to soil during dismantling. The different options for allocation the environmental burdens to electricity and heat show a wide range of possible results, depending on the choice of allocation parameters (energy, exergy, credits for heat or electricity, price) i.e. for the particles emissions: 161 mg/kWh el to minus 566 mg/kWh el , 0 mg/kWh th to 118 mg/kWh th . With the results of the analysis it is thus possible for future similar projects to know when and where significant environmental burdens might be further

  4. Energy System Analysis of Large-Scale Integration of Wind Power

    International Nuclear Information System (INIS)

    Lund, Henrik

    2003-11-01

    The paper presents the results of two research projects conducted by Aalborg University and financed by the Danish Energy Research Programme. Both projects include the development of models and system analysis with focus on large-scale integration of wind power into different energy systems. Market reactions and ability to exploit exchange on the international market for electricity by locating exports in hours of high prices are included in the analyses. This paper focuses on results which are valid for energy systems in general. The paper presents the ability of different energy systems and regulation strategies to integrate wind power, The ability is expressed by three factors: One factor is the degree of electricity excess production caused by fluctuations in wind and CHP heat demands. The other factor is the ability to utilise wind power to reduce CO 2 emission in the system. And the third factor is the ability to benefit from exchange of electricity on the market. Energy systems and regulation strategies are analysed in the range of a wind power input from 0 to 100% of the electricity demand. Based on the Danish energy system, in which 50 per cent of the electricity demand is produced in CHP, a number of future energy systems with CO 2 reduction potentials are analysed, i.e. systems with more CHP, systems using electricity for transportation (battery or hydrogen vehicles) and systems with fuel-cell technologies. For the present and such potential future energy systems different regulation strategies have been analysed, i.e. the inclusion of small CHP plants into the regulation task of electricity balancing and grid stability and investments in electric heating, heat pumps and heat storage capacity. Also the potential of energy management has been analysed. The results of the analyses make it possible to compare short-term and long-term potentials of different strategies of large-scale integration of wind power

  5. Reformate fuel cell system durability

    Energy Technology Data Exchange (ETDEWEB)

    Borup, R. L. (Rodney L.); Inbody, M. A. (Michael A.); Uribe, F. A. (Francisco A.); Tafoya, J. (Jose I.)

    2002-01-01

    The goal of this research is to identify the factors limiting the durability of fuel cells and fuel processors. This includes identifying PEM fuel cell durability issues for operating on pure hydrogen, and those that arise from the fuel processing of liquid hydrocarbons (e.g., gasoline) as a function of fuel composition and impurity content. Benchmark comparisons with the durability of fuel cells operating on pure hydrogen are used to identify limiting factors unique to fuel processing. We describe the design, operation and operational results of the durability system, including the operating conditions for the system, fuel processor sub-section operation over 1000 hours, post-mortem characterization of the catalysts in the fuel processor, and single cell operation.

  6. Techno-economic performance analysis of bio-oil based Fischer-Tropsch and CHP synthesis platform

    International Nuclear Information System (INIS)

    Ng, Kok Siew; Sadhukhan, Jhuma

    2011-01-01

    The techno-economic potential of the UK poplar wood and imported oil palm empty fruit bunch derived bio-oil integrated gasification and Fischer-Tropsch (BOIG-FT) systems for the generation of transportation fuels and combined heat and power (CHP) was investigated. The bio-oil was represented in terms of main chemical constituents, i.e. acetic acid, acetol and guaiacol. The compositional model of bio-oil was validated based on its performance through a gasification process. Given the availability of large scale gasification and FT technologies and logistic constraints in transporting biomass in large quantities, distributed bio-oil generations using biomass pyrolysis and centralised bio-oil processing in BOIG-FT system are technically more feasible. Heat integration heuristics and composite curve analysis were employed for once-through and full conversion configurations, and for a range of economies of scale, 1 MW, 675 MW and 1350 MW LHV of bio-oil. The economic competitiveness increases with increasing scale. A cost of production of FT liquids of 78.7 Euro/MWh was obtained based on 80.12 Euro/MWh of electricity, 75 Euro/t of bio-oil and 116.3 million Euro/y of annualised capital cost. -- Highlights: → Biomass to liquid process and gas to liquid process synthesis. → Biorefinery economic analysis. → Pyrolysis oil to biofuel. → Gasification and Fischer-Tropsch. → Process integration, pinch analysis and energy efficiency.

  7. Economic Potential of CHP in Detroit Edison Service Area: the Customer Perspective

    Energy Technology Data Exchange (ETDEWEB)

    Kelly, J.

    2003-10-10

    can realistically be expected, based on consumer investment in combined heat and power systems (CHP) and the effect of utility applied demand response (DR). (2) Evaluate and quantify the impact on the distribution utility feeder from the perspective of customer ownership of the DE equipment. (3) Determine the distribution feeder limits and the impact DE may have on future growth. For the case study, the Gas Technology Institute analyzed a single 16-megawatt grid feeder circuit in Ann Arbor, Michigan to determine whether there are economic incentives to use small distributed power generation systems that would offset the need to increase grid circuit capacity. Increasing circuit capacity would enable the circuit to meet consumer's energy demands at all times, but it would not improve the circuit's utilization factor. The analysis spans 12 years, to a planning horizon of 2015. By 2015, the demand for power is expected to exceed the grid circuit capacity for a significant portion of the year. The analysis was to determine whether economically acceptable implementation of customer-owned DE systems would reduce the peak power demands enough to forestall the need to upgrade the capacity of the grid circuit. The analysis was based on economics and gave no financial credit for improved power reliability or mitigation of environmental impacts. Before this study was completed, the utility expanded the capacity of the circuit to 22 MW. Although this expansion will enable the circuit to meet foreseeable increases in peak demand, it also will significantly decrease the circuit's overall utilization factor. The study revealed that DE penetration on the selected feeder is not expected to forestall the need to upgrade the grid circuit capacity unless interconnection barriers are removed. Currently, a variety of technical, business practice, and regulatory barriers discourage DE interconnection in the US market.

  8. Investigation of Continuous Gas Engine CHP Operation on Biomass Producer Gas

    DEFF Research Database (Denmark)

    Ahrenfeldt, Jesper; Henriksen, Ulrik Birk; Jensen, Torben Kvist

    2005-01-01

    investigated. The engine and the plant are equipped with continuously data acquisition that monitors the operation including the composition of the producer gas and the flow. Producer gas properties and contaminations have been investigated. No detectable tar or particle content was observed......More than 2000 hours of gas engine operation with producer gas from biomass as fuel has been conducted on the gasification CHP demonstration and research plant, named “Viking” at the Technical University of Denmark. The gas engine is an integrated part of the entire gasification plant. The excess...

  9. Anuário Investigação CHP 2008

    OpenAIRE

    DEFI

    2011-01-01

    Documenta-se a produção científica do Centro Hospitalar do Porto (CHP) apresentando os artigos da autoria ou co-autoria dos profissionais das três instituições nele integradas (Hospital de Santo António, HSA; Hospital Maria Pia, HMP; Maternidade Júlio Dinis, MJD) publicados em revistas científicas, durante o ano 2008.1 A listagem foi elaborada pelo Departamento de Ensino, Formação e Investigação (DEFI), com base em pesquisas em bases de dados bibliográficos. Consideram-se se...

  10. Anuário Investigação CHP 2009

    OpenAIRE

    DEFI

    2011-01-01

    Documenta-se a produção científica do Centro Hospitalar do Porto (CHP) apresentando os artigos da autoria ou co-autoria dos profissionais das três instituições nele integradas (Hospital de Santo António, HSA; Hospital Maria Pia, HMP; Maternidade Júlio Dinis, MJD) publicados em revistas científicas, durante o ano 2009.1 A listagem foi elaborada pelo Departamento de Ensino, Formação e Investigação (DEFI), com base em pesquisas em bases de dados bibliográficos. Consideram-se se...

  11. Anuário Investigação CHP 2010

    OpenAIRE

    DEFI

    2011-01-01

    Documenta-se a produção científica do Centro Hospitalar do Porto (CHP) apresentando os artigos da autoria ou co-autoria dos profissionais das três instituições nele integradas (Hospital de Santo António, HSA; Hospital Maria Pia, HMP; Maternidade Júlio Dinis, MJD) publicados em revistas científicas, durante o ano 2010.1 A listagem foi elaborada pelo Departamento de Ensino, Formação e Investigação (DEFI), com base em pesquisas em bases de dados bibliográficos. Consideram-se se...

  12. Choosing the Right Technologies – A Model for Cost Optimized Design of a Renewable Supply System for Residential Zero Energy Buildings

    DEFF Research Database (Denmark)

    Milan, Christian

    interests, when the control is adapted. Further, results show that the assumption of constant efficiencies for CHP technologies does not lead to large changes in investment decisions. However, considering flexible efficiencies might be important when optimizing operational schedules of an existing system...... involving fuel cells as their part load operation played a moderate role in the optimal solution of the conducted case studies. Additionally, a method is presented, which accounts for uncertainties in user behavior and weather profiles....

  13. Combined Heat and Power (CHP) as a Compliance Option under the Clean Power Plan: A Template and Policy Options for State Regulators

    Energy Technology Data Exchange (ETDEWEB)

    None

    2015-07-30

    Combined Heat and Power (CHP) is an important option for states to consider in developing strategies to meet their emission targets under the US Environmental Protection Agency's Clean Power Plan. This Template is designed to highlight key issues that states should consider when evaluating whether CHP could be a meaningful component of their compliance plans. It demonstrates that CHP can be a valuable approach for reducing emissions and helping states achieve their targets. While the report does not endorse any particular approach for any state, and actual plans will vary dependent upon state-specific factors and determinations, it provides tools and resources that states can use to begin the process, and underscores the opportunity CHP represents for many states. . By producing both heat and electricity from a single fuel source, CHP offers significant energy savings and carbon emissions benefits over the separate generation of heat and power, with a typical unit producing electricity with half the emissions of conventional generation. These efficiency gains translate to economic savings and enhanced competitiveness for CHP hosts, and emissions reductions for the state, along with helping to lower electric bills; and creating jobs in the design, construction, installation and maintenance of equipment. In 2015, CHP represents 8 percent of electric capacity in the United States and provides 12 percent of total power generation. Projects already exist in all 50 states, but significant technical and economic potential remains. CHP offers a tested way for states to achieve their emission limits while advancing a host of ancillary benefits.

  14. On-line experimental validation of a model-based diagnostic algorithm dedicated to a solid oxide fuel cell system

    Science.gov (United States)

    Polverino, Pierpaolo; Esposito, Angelo; Pianese, Cesare; Ludwig, Bastian; Iwanschitz, Boris; Mai, Andreas

    2016-02-01

    In the current energetic scenario, Solid Oxide Fuel Cells (SOFCs) exhibit appealing features which make them suitable for environmental-friendly power production, especially for stationary applications. An example is represented by micro-combined heat and power (μ-CHP) generation units based on SOFC stacks, which are able to produce electric and thermal power with high efficiency and low pollutant and greenhouse gases emissions. However, the main limitations to their diffusion into the mass market consist in high maintenance and production costs and short lifetime. To improve these aspects, the current research activity focuses on the development of robust and generalizable diagnostic techniques, aimed at detecting and isolating faults within the entire system (i.e. SOFC stack and balance of plant). Coupled with appropriate recovery strategies, diagnosis can prevent undesired system shutdowns during faulty conditions, with consequent lifetime increase and maintenance costs reduction. This paper deals with the on-line experimental validation of a model-based diagnostic algorithm applied to a pre-commercial SOFC system. The proposed algorithm exploits a Fault Signature Matrix based on a Fault Tree Analysis and improved through fault simulations. The algorithm is characterized on the considered system and it is validated by means of experimental induction of faulty states in controlled conditions.

  15. Combined heat and power systems: economic and policy barriers to growth

    Directory of Open Access Journals (Sweden)

    Kalam Adil

    2012-04-01

    Full Text Available Abstract Background Combined Heat and Power (CHP systems can provide a range of benefits to users with regards to efficiency, reliability, costs and environmental impact. Furthermore, increasing the amount of electricity generated by CHP systems in the United States has been identified as having significant potential for impressive economic and environmental outcomes on a national scale. Given the benefits from increasing the adoption of CHP technologies, there is value in improving our understanding of how desired increases in CHP adoption can be best achieved. These obstacles are currently understood to stem from regulatory as well as economic and technological barriers. In our research, we answer the following questions: Given the current policy and economic environment facing the CHP industry, what changes need to take place in this space in order for CHP systems to be competitive in the energy market? Methods We focus our analysis primarily on Combined Heat and Power Systems that use natural gas turbines. Our analysis takes a two-pronged approach. We first conduct a statistical analysis of the impact of state policies on increases in electricity generated from CHP system. Second, we conduct a Cost-Benefit analysis to determine in which circumstances funding incentives are necessary to make CHP technologies cost-competitive. Results Our policy analysis shows that regulatory improvements do not explain the growth in adoption of CHP technologies but hold the potential to encourage increases in electricity generated from CHP system in small-scale applications. Our Cost-Benefit analysis shows that CHP systems are only cost competitive in large-scale applications and that funding incentives would be necessary to make CHP technology cost-competitive in small-scale applications. Conclusion From the synthesis of these analyses we conclude that because large-scale applications of natural gas turbines are already cost-competitive, policy initiatives

  16. Combined heat and power systems: economic and policy barriers to growth.

    Science.gov (United States)

    Kalam, Adil; King, Abigail; Moret, Ellen; Weerasinghe, Upekha

    2012-04-23

    Combined Heat and Power (CHP) systems can provide a range of benefits to users with regards to efficiency, reliability, costs and environmental impact. Furthermore, increasing the amount of electricity generated by CHP systems in the United States has been identified as having significant potential for impressive economic and environmental outcomes on a national scale. Given the benefits from increasing the adoption of CHP technologies, there is value in improving our understanding of how desired increases in CHP adoption can be best achieved. These obstacles are currently understood to stem from regulatory as well as economic and technological barriers. In our research, we answer the following questions: Given the current policy and economic environment facing the CHP industry, what changes need to take place in this space in order for CHP systems to be competitive in the energy market? We focus our analysis primarily on Combined Heat and Power Systems that use natural gas turbines. Our analysis takes a two-pronged approach. We first conduct a statistical analysis of the impact of state policies on increases in electricity generated from CHP system. Second, we conduct a Cost-Benefit analysis to determine in which circumstances funding incentives are necessary to make CHP technologies cost-competitive. Our policy analysis shows that regulatory improvements do not explain the growth in adoption of CHP technologies but hold the potential to encourage increases in electricity generated from CHP system in small-scale applications. Our Cost-Benefit analysis shows that CHP systems are only cost competitive in large-scale applications and that funding incentives would be necessary to make CHP technology cost-competitive in small-scale applications. From the synthesis of these analyses we conclude that because large-scale applications of natural gas turbines are already cost-competitive, policy initiatives aimed at a CHP market dominated primarily by large-scale (and

  17. Spatial distribution of pollutants in the area of the former CHP plant

    Science.gov (United States)

    Cichowicz, Robert

    2018-01-01

    The quality of atmospheric air and level of its pollution are now one of the most important issues connected with life on Earth. The frequent nuisance and exceedance of pollution standards often described in the media are generated by both low emission sources and mobile sources. Also local organized energy emission sources such as local boiler houses or CHP plants have impact on air pollution. At the same time it is important to remember that the role of local power stations in shaping air pollution immission fields depends on the height of emitters and functioning of waste gas treatment installations. Analysis of air pollution distribution was carried out in 2 series/dates, i.e. 2 and 10 weeks after closure of the CHP plant. In the analysis as a reference point the largest intersection of streets located in the immediate vicinity of the plant was selected, from which virtual circles were drawn every 50 meters, where 31 measuring points were located. As a result, the impact of carbon dioxide, hydrogen sulfide and ammonia levels could be observed and analyzed, depending on the distance from the street intersection.

  18. Operating Experiences with a Small-scale CHP Pilot Plant based on a 35 kWel Hermetic Four Cylinder Stirling Engine for Biomass Fuels

    DEFF Research Database (Denmark)

    Biedermann, F.; Carlsen, Henrik; Schoech, M.

    2003-01-01

    Within the scope of the RD&D project presented a small-scale CHP plant with a hermetic four cylinder Stirling engine for biomass fuels was developed and optimised in cooperation with the Technical University of Denmark, MAWERA Holzfeuerungsanlagen GesmbH, an Austrian biomass furnace and boiler ma...... exchanger of the Stirling engine, of the air preheater and of the entire combustion system. Furthermore, the optimisation of the pneumatic cleaning system to reduce ash deposition in the hot heat exchanger is of great relevance....... manufacturer, and BIOS BIOENERGIESYSTEME GmbH, an Austrian development and engineering company. Based on the technology developed, a pilot plant was designed and erected in Austria. The nominal electric power output of the plant is 35 kWel and the nominal thermal output amounts to approx. 220 kWth. The plant...

  19. Are US utility standby rates inhibiting diffusion of customer-owned generating systems?

    International Nuclear Information System (INIS)

    Jackson, Jerry

    2007-01-01

    New, small-scale electric generation technologies permit utility customers to generate some of their own electric power and to utilize waste heat for space heating and other applications at the building site. This combined heat and power (CHP) characteristic can provide significant energy-cost savings. However, most current US utility regulations leave CHP standby rate specification largely to utility discretion resulting in claims by CHP advocates that excessive standby rates are significantly reducing CHP-related savings and inhibiting CHP diffusion. The impacts of standby rates on the adoption of CHP are difficult to determine; however, because of the characteristically slow nature of new technology diffusion. This study develops an agent-based microsimulation model of CHP technology choice using cellular automata to represent new technology information dispersion and knowledge acquisition. Applying the model as an n-factorial experiment quantifies the impacts of standby rates on CHP technologies under alternative diffusion paths. Analysis of a sample utility indicates that, regardless of the likely diffusion process, reducing standby rates to reflect the cost of serving a large number of small, spatially clustered CHP systems significantly increases the adoption of these technologies

  20. Fuel cell-fuel cell hybrid system

    Science.gov (United States)

    Geisbrecht, Rodney A.; Williams, Mark C.

    2003-09-23

    A device for converting chemical energy to electricity is provided, the device comprising a high temperature fuel cell with the ability for partially oxidizing and completely reforming fuel, and a low temperature fuel cell juxtaposed to said high temperature fuel cell so as to utilize remaining reformed fuel from the high temperature fuel cell. Also provided is a method for producing electricity comprising directing fuel to a first fuel cell, completely oxidizing a first portion of the fuel and partially oxidizing a second portion of the fuel, directing the second fuel portion to a second fuel cell, allowing the first fuel cell to utilize the first portion of the fuel to produce electricity; and allowing the second fuel cell to utilize the second portion of the fuel to produce electricity.

  1. Mechatronics in fuel cell systems

    Energy Technology Data Exchange (ETDEWEB)

    Stefanopoulou, Anna G.; Kyungwon Suh [Mechanical Engineering Department, University of Michigan, 1231 Beal Avenue, Ann Arbor, MI 48109, (United States)

    2007-03-15

    Power generation from fuel cells (FCs) requires the integration of chemical, fluid, mechanical, thermal, electrical, and electronic subsystems. This integration presents many challenges and opportunities in the mechatronics field. This paper highlights important design issues and poses problems that require mechatronics solutions. The paper begins by describing the process of designing a toy school bus powered by hydrogen for an undergraduate student project. The project was an effective and rewarding educational activity that revealed complex systems issues associated with FC technology. (Author)

  2. One-Step Printable Perovskite Films Fabricated under Ambient Conditions for Efficient and Reproducible Solar Cells.

    Science.gov (United States)

    Jung, Yen-Sook; Hwang, Kyeongil; Heo, Youn-Jung; Kim, Jueng-Eun; Lee, Donmin; Lee, Cheol-Ho; Joh, Han-Ik; Yeo, Jun-Seok; Kim, Dong-Yu

    2017-08-23

    Despite the potential of roll-to-roll processing for the fabrication of perovskite films, the realization of highly efficient and reproducible perovskite solar cells (PeSCs) through continuous coating techniques and low-temperature processing is still challenging. Here, we demonstrate that efficient and reliable CH 3 NH 3 PbI 3 (MAPbI 3 ) films fabricated by a printing process can be achieved through synergetic effects of binary processing additives, N-cyclohexyl-2-pyrrolidone (CHP) and dimethyl sulfoxide (DMSO). Notably, these perovskite films are deposited from premixed perovskite solutions for facile one-step processing under a room-temperature and ambient atmosphere. The CHP molecules result in the uniform and homogeneous perovskite films even in the one-step slot-die system, which originate from the high boiling point and low vapor pressure of CHP. Meanwhile, the DMSO molecules facilitate the growth of perovskite grains by forming intermediate states with the perovskite precursor molecules. Consequently, fully printed PeSC based on the binary additive system exhibits a high PCE of 12.56% with a high reproducibility.

  3. Life cycle assessment of micro production technologies - solar cells, household wind turbines and micro motors; Livscyklusvurdering af mikroproduktionsteknologier - solceller, husstandsvindmoeller og mikromotorer

    Energy Technology Data Exchange (ETDEWEB)

    Faeborg Poulsen, A.; Kruse, H.; Hvid Ipsen, K.

    2000-07-15

    This report contains a life cycle based estimation of environmental effects of CHP based on the micro production technologies: solar cells, household wind turbines and micro motors. The technologies cover CHP production on very small plants which are characterised by being located by the individual consumer. (BA)

  4. Combined Heat and Power Systems for the Provision of Sustainable Energy from Biomass in Buildings

    Directory of Open Access Journals (Sweden)

    Ortwein Andreas

    2016-01-01

    Full Text Available Against the background of greenhouse gases causing climate change, combined heat and power (CHP systems fueled by biomass can efficiently supply energy with high flexibility. Such CHP systems will usually consist of one or more thermo-chemical conversion steps and at least one (the more or less separated electric power generation unit. Depending on the main products of the previous conversion steps (e.g. combustible gases or liquids, but also flue gases with sensible heat, different technologies are available for the final power conversion step. This includes steam cycles with steam turbines or engines and different working fluids (water, organic fluids, but also combustion based systems like gas turbines or gas engines. Further promising technologies include fuel cells with high electric efficiency. When integrating such CHP systems in buildings, there are different strategies, especially concerning electric power generation. While some concepts are focusing on base load production, others are regulated either by thermal or by electric power demand. The paper will give a systematic overview on the combination of thermo-chemical conversion of biomass and combined heat and power production technologies. The mentioned building integration strategies will be discussed, leading to conclusions for further research and development in that field.

  5. In-situ corrosion investigation at Masnedø CHP plant - a straw-fired power plant

    DEFF Research Database (Denmark)

    Montgomery, Melanie; Karlsson, Asger

    1999-01-01

    Various austenitic and ferritic steels were exposed on a water-cooled probe in the superheater area of a straw-fired CHP plant. The temperature of the probe ranged from 450-600°C and the period of exposure was 1400 hours. The rate of corrosion was assessed based on unattacked metal remaining. The...

  6. Modelling of a steam reformer for fuel cell CHP systems considering intra- and extra-particulate transport phenomena; Modellierung eines Dampfreformers fuer stationaere Brennstoffzellen unter Beruecksichtigung von intra- und extrapartikulaeren Transportphaenomene

    Energy Technology Data Exchange (ETDEWEB)

    Nitzsche, J. [DBI-Gastechnologisches Institut, Freiberg (Germany)

    2009-07-01

    The modelling of methane steam-reforming fixed bed reactors requires detailed knowledge of limiting heat and mass transfer processes at the catalyst particle. Their influence is checked by a single particle model and the results are used to create an exact two-dimensional model of a reformer tube. This model allows for the implementation of an intensive significance analysis, which gives a better understanding of the process and provides for proper dimensioning of steam reformers. (orig.)

  7. Modelling a Combined Heat and Power Plant based on Gasification, Micro Gas Turbine and Solid Oxide Fuel Cells

    DEFF Research Database (Denmark)

    Bang-Møller, Christian; Rokni, Masoud

    2009-01-01

    A system level modelling study on two combined heat and power (CHP) systems both based on biomass gasification. One system converts the product gas in a micro gas turbine (MGT) and the other in a combined solid oxide fuel cell (SOFC) and MGT arrangement. An electrochemical model of the SOFC has...... been developed and calibrated against published data from Topsoe Fuel Cells A/S (TOFC) and Risø National Laboratory, and the modelled gasifier is based on an up scaled version of the demonstrated low tar gasifier, Viking, situated at the Technical University of Denmark. The SOFC converts the syngas...

  8. Fuel cell system blower configuration

    Energy Technology Data Exchange (ETDEWEB)

    Patel, Kirtikumar H.; Saito, Kazuo

    2017-11-28

    An exemplary fuel cell system includes a cell stack assembly having a plurality of cathode components and a plurality of anode components. A first reactant blower has an outlet situated to provide a first reactant to the cathode components. A second reactant blower has an outlet situated to provide a second reactant to the anode components. The second reactant blower includes a fan portion that moves the second reactant through the outlet. The second reactant blower also includes a motor portion that drives the fan portion and a bearing portion associated with the fan portion and the motor portion. The motor portion has a motor coolant inlet coupled with the outlet of the first reactant blower to receive some of the first reactant for cooling the motor portion.

  9. Fluorescent multiplex cell flow systems and methods

    KAUST Repository

    Merzaban, Jasmeen

    2017-06-01

    Systems and methods are provided for simultaneously assaying cell adhesion or cell rolling for multiple cell specimens. One embodiment provides a system for assaying adhesion or cell rolling of multiple cell specimens that includes a confocal imaging system containing a parallel plate flow chamber, a pump in fluid communication with the parallel plate flow chamber via a flow chamber inlet line and a cell suspension in fluid communication with the parallel plate flow chamber via a flow chamber outlet line. The system also includes a laser scanning system in electronic communication with the confocal imaging system, and a computer in communication with the confocal imaging system and laser scanning system. In certain embodiments, the laser scanning system emits multiple electromagnetic wavelengths simultaneously it cause multiple fluorescent labels having different excitation wavelength maximums to fluoresce. The system can simultaneously capture real-time fluorescence images from at least seven cell specimens in the parallel plate flow chamber.

  10. Techno-economic analysis of using corn stover to supply heat and power to a corn ethanol plant - Part 2: Cost of heat and power generation systems

    International Nuclear Information System (INIS)

    Mani, S.; Sokhansanj, S.; Tagore, S.; Turhollow, A.F.

    2010-01-01

    This paper presents a techno-economic analysis of corn stover fired process heating (PH) and the combined heat and power (CHP) generation systems for a typical corn ethanol plant (ethanol production capacity of 170 dam 3 ). Discounted cash flow method was used to estimate both the capital and operating costs of each system and compared with the existing natural gas fired heating system. Environmental impact assessment of using corn stover, coal and natural gas in the heat and/or power generation systems was also evaluated. Coal fired process heating (PH) system had the lowest annual operating cost due to the low fuel cost, but had the highest environmental and human toxicity impacts. The proposed combined heat and power (CHP) generation system required about 137 Gg of corn stover to generate 9.5 MW of electricity and 52.3 MW of process heat with an overall CHP efficiency of 83.3%. Stover fired CHP system would generate an annual savings of 3.6 M$ with an payback period of 6 y. Economics of the coal fired CHP system was very attractive compared to the stover fired CHP system due to lower fuel cost. But the greenhouse gas emissions per Mg of fuel for the coal fired CHP system was 32 times higher than that of stover fired CHP system. Corn stover fired heat and power generation system for a corn ethanol plant can improve the net energy balance and add environmental benefits to the corn to ethanol biorefinery.

  11. COMPARISON OF MATHEMATICAL MODELS FOR HEAT EXCHANGERS OF UNCONVENTIONAL CHP UNITS

    Directory of Open Access Journals (Sweden)

    Peter Durcansky

    2015-08-01

    Full Text Available An unconventional CHP unit with a hot air engine is designed as the primary energy source with fuel in the form of biomass. The heat source is a furnace designed for combustion of biomass, whether in the form of wood logs or pellets. The transport of energy generated by the biomass combustion to the working medium of a hot-air engine is ensured by a special heat exchanger connected to this resource. The correct operation of the hot-air engine is largely dependent on an appropriate design of the exchanger. The paper deals with the calculation of the heat exchanger for the applicationsmentioned, using criterion equations, and based on CFD simulations.

  12. The effectiveness of absorption heat pumps application for the increase of economic efficiency of CHP operation

    Directory of Open Access Journals (Sweden)

    Luzhkovoy Dmitriy S.

    2017-01-01

    Full Text Available The article deals with a comparative analysis of CHP operational efficiency in various working modes before and after the absorption heat pumps installation. The calculation was performed using a mathematical model of the extraction turbine PT- 80/100-130/13. Absorption heat pumps of LLC “OKB Teplosibmash” were used as AHP models for the analysis. The most effective way of absorption lithium-bromide heat pumps application as a part of the turbine PT-80/100-130/13 turned out to be their usage in a heat-producing mode during a non-heating season with a load of hot water supply. For this mode the dependence of the turbine heat efficiency on the heat load of the external consumer at a given throttle flow was analyzed.

  13. Implications of the modelling of stratified hot water storage tanks in the simulation of CHP plants

    Energy Technology Data Exchange (ETDEWEB)

    Campos Celador, A., E-mail: alvaro.campos@ehu.es [ENEDI Research Group-University of the Basque Country, Departamento de Maquinas y Motores Termicos, E.T.S.I. de Bilbao Alameda de Urquijo, s/n 48013 Bilbao, Bizkaia (Spain); Odriozola, M.; Sala, J.M. [ENEDI Research Group-University of the Basque Country, Departamento de Maquinas y Motores Termicos, E.T.S.I. de Bilbao Alameda de Urquijo, s/n 48013 Bilbao, Bizkaia (Spain)

    2011-08-15

    Highlights: {yields} Three different modelling approaches for simulation of hot water tanks are presented. {yields} The three models are simulated within a residential cogeneration plant. {yields} Small differences in the results are found by an energy and exergy analysis. {yields} Big differences between the results are found by an advanced exergy analysis. {yields} Results on the feasibility study are explained by the advanced exergy analysis. - Abstract: This paper considers the effect that different hot water storage tank modelling approaches have on the global simulation of residential CHP plants as well as their impact on their economic feasibility. While a simplified assessment of the heat storage is usually considered in the feasibility studies of CHP plants in buildings, this paper deals with three different levels of modelling of the hot water tank: actual stratified model, ideal stratified model and fully mixed model. These three approaches are presented and comparatively evaluated under the same case of study, a cogeneration plant with thermal storage meeting the loads of an urbanisation located in the Bilbao metropolitan area (Spain). The case of study is simulated by TRNSYS for each one of the three modelling cases and the so obtained annual results are analysed from both a First and Second-Law-based viewpoint. While the global energy and exergy efficiencies of the plant for the three modelling cases agree quite well, important differences are found between the economic results of the feasibility study. These results can be predicted by means of an advanced exergy analysis of the storage tank considering the endogenous and exogenous exergy destruction terms caused by the hot water storage tank.

  14. Estimating cell capacity for multi-cell electrical energy system

    Science.gov (United States)

    Hashemi, Iman Ahari

    A Multi-Cell Electrical Energy System is a set of batteries that are connected in series. The series batteries provide the required voltage necessary for the contraption. After using the energy that is provided by the batteries, some cells within the system tend to have a lower voltage than the other cells. Also, other factors, such as the number of times a battery has been charged or discharged, how long it has been within the system and many other factors, result in some cells having a lesser capacity compared to the other cells within the system. The outcome is that it lowers the required capacity that the electrical energy system is required to provide. By having an unknown cell capacity within the system, it is unknown how much of a charge can be provided to the system so that the cells are not overcharged or undercharged. Therefore, it is necessary to know the cells capacity within the system. Hence, if we were dealing with a single cell, the capacity could be obtained by a full charge and discharge of the cell. In a series system that contains multiple cells a full charging or discharging cannot happen as it might result in deteriorating the structure of some cells within the system. Hence, to find the capacity of a single cell within an electrical energy system it is required to obtain a method that can estimate the value of each cell within the electrical energy system. To approach this method an electrical energy system is required. The electrical energy system consists of rechargeable non-equal capacity batteries to provide the required energy to the system, a battery management system (BMS) board to monitor the cells voltages, an Arduino board that provides the required communication to BMS board, and the PC, and a software that is able to deliver the required data obtained from the Arduino board to the PC. The outcome, estimating the capacity of a cell within a multi-cell system, can be used in many battery related technologies to obtain unknown

  15. Fuel-cell engine stream conditioning system

    Science.gov (United States)

    DuBose, Ronald Arthur

    2002-01-01

    A stream conditioning system for a fuel cell gas management system or fuel cell engine. The stream conditioning system manages species potential in at least one fuel cell reactant stream. A species transfer device is located in the path of at least one reactant stream of a fuel cell's inlet or outlet, which transfer device conditions that stream to improve the efficiency of the fuel cell. The species transfer device incorporates an exchange media and a sorbent. The fuel cell gas management system can include a cathode loop with the stream conditioning system transferring latent and sensible heat from an exhaust stream to the cathode inlet stream of the fuel cell; an anode humidity retention system for maintaining the total enthalpy of the anode stream exiting the fuel cell related to the total enthalpy of the anode inlet stream; and a cooling water management system having segregated deionized water and cooling water loops interconnected by means of a brazed plate heat exchanger.

  16. Human neuroblastoma cell growth in xenogeneic hosts: comparison of T cell-deficient and NK-deficient hosts, and subcutaneous or intravenous injection routes.

    Science.gov (United States)

    Turner, W J; Chatten, J; Lampson, L A

    1990-04-01

    We have examined two features of neuroblastoma cells that had not been well-characterized in a xenogeneic model: The cells display unusual immunologic properties in other experimental systems, and the original tumors display widespread and characteristic patterns of metastasis. To determine the most appropriate immunodeficient host for primary tumor growth, T cell-deficient nude mice, NK-deficient beige mice, beige-nudes, and controls were injected with the well-characterized line CHP-100. To define the pattern of tumor spread, complete autopsies were performed following subcutaneous, intraperitoneal and intravenous injections. CHP-100 consistently formed subcutaneous tumors in T cell-deficient mice (nude and beige-nude), but not in T cell-competent mice (beige, heterozygous nu/+ and bg/+, or wild-type). The growth rate and final size of the subcutaneous tumors were not greater in beige-nudes than in nudes. All mice showed early CHP-100 cell death after subcutaneous injection; the nature of the immunodeficiency was more relevant for the surviving subpopulation. Widespread dissemination was seen following intravenous injection, particularly in beige-nudes. Aspects of the growth patterns were appropriate to the tumor of origin. The behavior in immunodeficient mice suggests that T cells can play a role in controlling the growth of these cells; the next steps will be to define the effector mechanisms, and to determine if they can be exploited for human patients. The hematogenous spread following intravenous injection suggests that insights into the control of blood-borne tumor may also come from further study of this model.

  17. Battery Cell Balancing System and Method

    Science.gov (United States)

    Davies, Francis J. (Inventor)

    2014-01-01

    A battery cell balancing system is operable to utilize a relatively small number of transformers interconnected with a battery having a plurality of battery cells to selectively charge the battery cells. Windings of the transformers are simultaneously driven with a plurality of waveforms whereupon selected battery cells or groups of cells are selected and charged. A transformer drive circuit is operable to selectively vary the waveforms to thereby vary a weighted voltage associated with each of the battery cells.

  18. Opportunity and potential for fuel cell systems for energy in buildings; Moejlighet och potential foer braenslecellsystem foer energifoersoerjning i byggnader

    Energy Technology Data Exchange (ETDEWEB)

    Jannasch, Anna-Karin (Catator AB (Sweden))

    2011-04-15

    While planning for new sustainable and environmentally friendly communities in Sweden, discussions on using fuel cells for small-scale power and heat production (mCHP) are today on-going. Examples of such communities are Sege Park in Malmoe and Norra Djurgardsstaden in Stockholm, where several members of the Swedish Construction Industry's Organisation for Research and Development (SBUF) are participating in the development. The status and the potential of using fuel cell based mCHP compared to conventional heat and power production technology and other mCHP-technologies (Internal combustion engine (ICE), Stirling) is today therefore a very interesting question for both the energy and the building sector, who also ask for more knowledge within the field. This work focuses on this purpose. The main goals of this report are: 1. To give an overall description of different existing fuel cell technologies and necessary belonging system components. The fuel cell systems are discussed and evaluated based on parameters such as efficiencies, fuel flexibility, life-time, complexity, maturity and cost. The systems are compared to mCHPs based on small heat engines (Internal combustion, Stirling). 2. To give a state-of-the-art report on fuel cell based mCHPs and to describe possibilities and risks related to different technologies. 3. To guideline for future choices of system solutions suitable for different building constructions and different geographical placements. The work is limited to systems suitable for small houses (< 5 kWe) and larger residential buildings (< 50 kWe) situated in population centres/cities where infra-structures for natural gas/biogas and the national grid are available. The project has been performed by Catator AB on the request of SBUF with support from the Swedish Gas Centre (SGC AB), Skanska and Catator. The study is based on the open literature, the information given by leading fuel cell system suppliers and Catator's own knowledge and

  19. Modular PEM Fuel Cell SCADA & Simulator System

    Directory of Open Access Journals (Sweden)

    Francisca Segura

    2015-09-01

    Full Text Available The paper presents a Supervision, Control, Data Acquisition and Simulation (SCADA & Simulator system that allows for real-time training in the actual operation of a modular PEM fuel cell system. This SCADA & Simulator system consists of a free software tool that operates in real time and simulates real situations like failures and breakdowns in the system. This developed SCADA & Simulator system allows us to properly operate a fuel cell and helps us to understand how fuel cells operate and what devices are needed to configure and run the fuel cells, from the individual stack up to the whole fuel cell system. The SCADA & Simulator system governs a modular system integrated by three PEM fuel cells achieving power rates higher than tens of kilowatts.

  20. Chip based electroanalytical systems for cell analysis

    DEFF Research Database (Denmark)

    Spegel, C.; Heiskanen, A.; Skjolding, L.H.D.

    2008-01-01

    ' measurements of processes related to living cells, i.e., systems without lysing the cells. The focus is on chip based amperometric and impedimetric cell analysis systems where measurements utilizing solely carbon fiber microelectrodes (CFME) and other nonchip electrode formats, such as CFME for exocytosis...

  1. High-affinity binding of Chp1 chromodomain to K9 methylated histone H3 is required to establish centromeric heterochromatin.

    Science.gov (United States)

    Schalch, Thomas; Job, Godwin; Noffsinger, Victoria J; Shanker, Sreenath; Kuscu, Canan; Joshua-Tor, Leemor; Partridge, Janet F

    2009-04-10

    In fission yeast, assembly of centromeric heterochromatin requires the RITS complex, which consists of Ago1, Tas3, Chp1, and siRNAs derived from centromeric repeats. Recruitment of RITS to centromeres has been proposed to depend on siRNA-dependent targeting of Ago1 to centromeric sequences. Previously, we demonstrated that methylated lysine 9 of histone H3 (H3K9me) acts upstream of siRNAs during heterochromatin establishment. Our crystal structure of Chp1's chromodomain in complex with a trimethylated lysine 9 H3 peptide reveals extensive sites of contact that contribute to Chp1's high-affinity binding. We found that this high-affinity binding is critical for the efficient establishment of centromeric heterochromatin, but preassembled heterochromatin can be maintained when Chp1's affinity for H3K9me is greatly reduced.

  2. Glial Cells: The Other Cells of the Nervous System

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 7; Issue 1. Glial Cells: The Other Cells of the Nervous System - An Introduction to Glial Cells. Medha S Rajadhyaksha Yasmin Khan. Series Article Volume 7 Issue 1 January 2002 pp 4-10 ...

  3. Secure Automated Microgrid Energy System (SAMES)

    Science.gov (United States)

    2016-12-01

    types of DER include, but are not limited to, solar photovoltaic ( PV ), energy storage (ES), and combined heat and power (CHP). Solar PV Systems The...Energy Commission CHP Combined Heat and Power CIO Chief Information Officer DCS Distributed Control System DER Distributed Energy Resources...Short circuit 69 • Arc Heat (arc flash) • Power Systems Optimization (optimal power flow) Six scenarios were evaluated against the power analysis

  4. Economic, energy and GHG emissions performance evaluation of a WhisperGen Mk IV Stirling engine μ-CHP unit in a domestic dwelling

    International Nuclear Information System (INIS)

    Conroy, G.; Duffy, A.; Ayompe, L.M.

    2014-01-01

    Highlights: • The performance of a Stirling engine MK IV micro-CHP unit was evaluated in a domestic dwelling in Ireland. • The performance of the micro-CHP was compare to that of a condensing gas boiler. • The micro-CHP unit resulted in an annual cost saving of €180 compared to the condensing gas boiler. • Electricity imported from the grid decreased by 20.8% while CO 2 emissions decreased by 16.1%. • The micro-CHP unit used 2889 kW h of gas more than the condensing gas boiler during one year of operation. - Abstract: This paper presents an assessment of the energy, economic and greenhouse gas emissions performances of a WhisperGen Mk IV Stirling engine μ-CHP unit for use in a conventional house in the Republic of Ireland. The energy performance data used in this study was obtained from a field trial carried out in Belfast, Northern Ireland during the period June 2004–July 2005 by Northern Ireland Electricity and Phoenix Gas working in collaboration with Whispertech UK. A comparative performance analysis between the μ-CHP unit and a condensing gas boiler revealed that the μ-CHP unit resulted in an annual cost saving of €180 with an incremental simple payback period of 13.8 years when compared to a condensing gas boiler. Electricity imported from the grid decreased by 20.8% while CO 2 emissions decreased by 16.1%. The μ-CHP unit used 2889 kW h of gas more than the condensing gas boiler

  5. Fundamentals of fuel cell system integration

    Science.gov (United States)

    Krumpelt, Michael; Kumar, Romesh; Myles, Kevin M.

    1994-04-01

    Fuel cells are theoretically very efficient energy conversion devices that have the potential of becoming a commercial product for numerous uses in the civilian economy. We have analyzed several fuel cell system designs with regard to thermal and chemical integration of the fuel cell stack into the rest of the system. Thermal integration permits the use of the stack waste heat for the endothermic steps of fuel reforming. Chemical integration provides the steam needed for fuel reforming from the water produced by the electrochemical cell reaction. High-temperature fuel cells, such as the molten carbonate and the solid oxide fuel cells, permit this system integration in a relatively simple manner. Lower temperature fuel cells, such as the polymer electrolyte and phosphoric acid systems, require added system complexity to achieve such integration. The system economics are affected by capital and fuel costs and technical parameters, such as electrochemical fuel utilization, current density, and system complexity. At today's low fuel prices and the high fuel cell costs (in part, because of the low rates of production of the early prototypes), fuel cell systems are not cost competitive with conventional power generation. With the manufacture and sale of larger numbers of fuel cell systems, the total costs will decrease from the current several thousand dollars per kW, to perhaps less than $100 per kW as production volumes approa ch a million units per year.

  6. Optimal fuel-mix in CHP plants under a stochastic permit price. Risk-neutrality versus risk-aversion

    International Nuclear Information System (INIS)

    Lappi, Pauli; Ollikka, Kimmo; Ollikainen, Markku

    2010-01-01

    This paper studies the optimal fuel-mix of a CHP producer under emission permit price risk. The producer's multi-fuel plant uses two CO 2 -intensive fuels and one clean fuel. Using a mean-variance framework we develop three models. The models are divided into spot-models (risk neutral and risk averse cases) and a forward-model (risk averse case). We derive the effects of price risk on optimal fuel use. An increase in price risk can in fact increase the use of CO 2 -intensive fuel in the spot-model. In the forward-model, the production and financial decisions are separate. We also evaluate the risk-bearing behavior of seven Finnish CHP producers. We found that risk-neutrality describes behavior better than risk-aversion. (author)

  7. Cell boundary fault detection system

    Science.gov (United States)

    Archer, Charles Jens [Rochester, MN; Pinnow, Kurt Walter [Rochester, MN; Ratterman, Joseph D [Rochester, MN; Smith, Brian Edward [Rochester, MN

    2009-05-05

    A method determines a nodal fault along the boundary, or face, of a computing cell. Nodes on adjacent cell boundaries communicate with each other, and the communications are analyzed to determine if a node or connection is faulty.

  8. Glial Cells: The Other Cells of the Nervous System ...

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 7; Issue 6. Glial Cells: The Other Cells of the Nervous System - Oligodendrocytes – Ensheathers of the CNS. Yasmin Khan Medha S Rajadhyaksha. Series Article Volume 7 Issue 6 June 2002 pp 6-13 ... Keywords. Glia; myelin; central nervous system.

  9. Well-Controlled Cell-Trapping Systems for Investigating Heterogeneous Cell-Cell Interactions.

    Science.gov (United States)

    Kamiya, Koki; Abe, Yuta; Inoue, Kosuke; Osaki, Toshihisa; Kawano, Ryuji; Miki, Norihisa; Takeuchi, Shoji

    2018-03-01

    Microfluidic systems have been developed for patterning single cells to study cell-cell interactions. However, patterning multiple types of cells to understand heterogeneous cell-cell interactions remains difficult. Here, it is aimed to develop a cell-trapping device to assemble multiple types of cells in the well-controlled order and morphology. This device mainly comprises a parylene sheet for assembling cells and a microcomb for controlling the cell-trapping area. The cell-trapping area is controlled by moving the parylene sheet on an SU-8 microcomb using tweezers. Gentle downward flow is used as a driving force for the cell-trapping. The assembly of cells on a parylene sheet with round and line-shaped apertures is demonstrated. The cell-cell contacts of the trapped cells are then investigated by direct cell-cell transfer of calcein via connexin nanopores. Finally, using the device with a system for controlling the cell-trapping area, three different types of cells in the well-controlled order are assembled. The correct cell order rate obtained using the device is 27.9%, which is higher than that obtained without the sliding parylene system (0.74%). Furthermore, the occurrence of cell-cell contact between the three cell types assembled is verified. This cell-patterning device will be a useful tool for investigating heterogeneous cell-cell interactions. © 2018 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  10. Systems Biology and Stem Cell Pluripotency

    DEFF Research Database (Denmark)

    Mashayekhi, Kaveh; Hall, Vanessa Jane; Freude, Kristine

    2016-01-01

    Recent breakthroughs in stem cell biology have accelerated research in the area of regenerative medicine. Over the past years, it has become possible to derive patient-specific stem cells which can be used to generate different cell populations for potential cell therapy. Systems biological...... improve systems biology and its uses in the field. In this chapter, we first give a general background on stem cell biology and regenerative medicine. Stem cell potency is introduced together with the hierarchy of stem cells ranging from pluripotent embryonic stem cells (ESCs) and induced pluripotent stem...... modeling of stem cell pluripotency and differentiation have largely been based on prior knowledge of signaling pathways, gene regulatory networks, and epigenetic factors. However, there is a great need to extend the complexity of the modeling and to integrate different types of data, which would further...

  11. Solid oxide fuel cells towards real life applications. Final report

    Energy Technology Data Exchange (ETDEWEB)

    2010-07-01

    Solid Oxide Fuel Cells offer a clean and efficient way of producing electricity and heat from a wide selection of fuels. The project addressed three major challenges to be overcome by the technology to make commercialisation possible. (1) At the cell level, increased efficiency combined with production cost reduction has been achieved through an optimization of the manufacturing processes, b) by using alternative raw materials with a lower purchase price and c) by introducing a new generation of fuel cells with reduced loss and higher efficiency. (2) At the stack level, production cost reduction is reduced and manufacturing capacity is increased through an optimization of the stack production. (3) At the system level, development of integrated hotbox concepts for the market segments distributed generation (DG), micro combined heat and power (mCHP), and auxiliary power units (APU) have been developed. In the mCHP segment, two concepts have been developed and validated with regards to market requirements and scalability. In the APU-segment, different types of reformers have been tested and it has been proven that diesel can be reformed through appropriate reformers. Finally, operation experience and feedback has been gained by deployment of stacks in the test facility at the H.C. OErsted Power Plant (HCV). This demonstration has been carried out in collaboration between TOFC and DONG Energy Power A/S (DONG), who has participated as a subcontractor to TOFC. The demonstration has given valuable knowledge and experience with design, start-up and operation of small power units connected to the grid and future development within especially the mCHP segment will benefit from this. In this report, the project results are described for each of the work packages in the project. (Author)

  12. Implementation strategy for small CHP-plants in a competitive market: the case of Lithuania

    International Nuclear Information System (INIS)

    Lund, H.; Siupsinskas, G.; Martinaitis, V.

    2005-01-01

    Within five years from now, Lithuania is going to close down Ignalina, the only nuclear-power plant in the country. Since Ignalina generates more than 75% of the Lithuanian electricity production, new generation capacities are needed. Traditional steam-turbines, fuelled with fossil fuels, would mean further imports of fuel as well as a rise in CO 2 emissions. At the same time, several small district-heating companies one suffering from high heating-prices. Typically, the price in small towns is 20-50% higher than the price in large urban areas. Consequently, alternative strategies should be considered. This article analyses the conditions for one such strategy, namely the replacement of boilers in the existing district-heating supplies with combined heat-and-power production (CHP). Compared with new power stations, fuel can be saved and CO 2 -emissions reduced. Also this strategy can be used to level the difference between low heating prices in the large urban areas and high prices in small towns and villages. (Author)

  13. Hydrocarbon emissions from gas engine CHP-units. 2011 measurement program

    Energy Technology Data Exchange (ETDEWEB)

    Van Dijk, G.H.J. [KEMA, Arnhem (Netherlands)

    2012-06-15

    In December 2009, the Ministry of Infrastructure and Environment (IandM) issued the Decree on Emission Limits for Middle Sized Combustion Installations (BEMS). This decree imposes a first-time emission limit value (ELV) of 1500 mg C/m{sup 3}{sub o} at 3% O{sub 2} for hydrocarbons emitted by gas engines. IandM used the findings of two hydrocarbon emission measurement programs, executed in 2007 and 2009, as a guideline for this initial ELV. The programs did reveal substantial variation in the hydrocarbon emissions of the gas engines tested. This variation, and especially the uncertainty as to the role of engine and/or other parameters causing such variation, was felt to hamper further policy development. IandM therefore commissioned KEMA to perform follow-up measurements on ten gas engine CHP-units in 2011. Aim of this 2011 program is to assess hydrocarbon emission variation in relation to engine parameters and process conditions including maintenance status, and to atmospheric conditions. The 2011 program comprised two identical measurement sessions, one in spring and one in winter.

  14. Woking Park PAFC CHP monitoring. Phase 1: Planning, installation and commissioning

    Energy Technology Data Exchange (ETDEWEB)

    Goulding, P.S.; Fry, M.R.

    2003-07-01

    This report covers the planning, installation and commissioning of the first commercially operated fuel cell cogeneration system in the UK. The involvement of Woking Borough Council, its approach to energy efficiency, and the Woking Park site are discussed, and details are given of the PC25/C 200kW fuel cell which is manufactured in the US by UTC Fuel Cells. A description of the Woking Park fuel cell combined heat and power application is presented, and the project economics, specification and tendering are examined. The route taken to planning approval is traced, and installation procedures are outlined. The testing of the phosphoric type PC25 fuel cell cogeneration unit is described, and expected cost and project timescales are noted.

  15. Innovative High Temperature Fuel Cell systems

    NARCIS (Netherlands)

    Au, Siu Fai

    2003-01-01

    The world's energy consumption is growing extremely rapidly. Fuel cell systems are of interest by researchers and industry as the more efficient alternative to conventional thermal systems for power generation. The principle of fuel cell conversion does not involve thermal combustion and hence in

  16. Exergy analysis and optimization of a biomass gasification, solid oxide fuel cell and micro gas turbine hybrid system

    DEFF Research Database (Denmark)

    Bang-Møller, Christian; Rokni, Masoud; Elmegaard, Brian

    2011-01-01

    A hybrid plant producing combined heat and power (CHP) from biomass by use of a two-stage gasification concept, solid oxide fuel cells (SOFC) and a micro gas turbine was considered for optimization. The hybrid plant represents a sustainable and efficient alternative to conventional decentralized...... and exergy analyses were applied. Focus in this optimization study was heat management, and the optimization efforts resulted in a substantial gain of approximately 6% in the electrical efficiency of the plant. The optimized hybrid plant produced approximately 290 kWe at an electrical efficiency of 58...

  17. Cancer stem cells of the digestive system.

    Science.gov (United States)

    Colvin, Hugh S; Nishida, Naohiro; Koseki, Jun; Konno, Masamitsu; Kawamoto, Koichi; Tsunekuni, Kenta; Doki, Yuichiro; Mori, Masaki; Ishii, Hideshi

    2014-12-01

    Stem cells of the digestive system are ideal in many ways for research, given they are abundant, highly proliferative and have a uniform structural arrangement. This in turn has enormously aided the research of cancer stem cells of the digestive system, which is now shaping our understanding of cancer stem cells. In this review, the recent advances in the understanding of cancer stem cells of the digestive system have been summarized, including aspects such as their identification, origin, cell-cycle dormancy, relationship with epithelial-mesenchymal transition, cellular metabolism and the underlying molecular mechanisms. Newly acquired knowledge concerning cancer stem cells have led to the development of novel cancer therapeutics with provisional yet encouraging results. © The Author 2014. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  18. Fuel cell systems and production aspects

    Energy Technology Data Exchange (ETDEWEB)

    Blomen, L.J.M.J. [Blomenco, Rumpt (Netherlands)

    1995-02-01

    Attention is paid to some system integration and production aspects of fuel cell systems. After an introduction of the main performance differences of fuel cell systems with different types of fuel cells, and the causes for such differences, a few aspects of building up sub-systems towards large and small capacity fuel cell systems are being discussed. Subsequently, some production aspects are being highlighted: the concept of an automated plant and automated plant contracting, the trends towards greater simplicity m reactors, and a systematic evaluation of the differences in fuel processing steps required in systems with different types of fuel cells. In this section also the cost aspects of a total plant contracting project are being discussed. As a next step, some emphasis has been placed on system integration aspects, explaining that hydrogen purification does not always `destroy` system efficiency, and can be used in dispersed hydrogen generation concepts. Advanced system integration concepts include simplified flow sheet design, in which instead of special dedicated rotating equipment standard gas turbine rotary components are being employed. As an example, it is claimed that gas turbine - fuel cell combinations can be made with very high electrical efficiencies. 5 figs., 2 tabs.

  19. Water reactive hydrogen fuel cell power system

    Science.gov (United States)

    Wallace, Andrew P; Melack, John M; Lefenfeld, Michael

    2014-01-21

    A water reactive hydrogen fueled power system includes devices and methods to combine reactant fuel materials and aqueous solutions to generate hydrogen. The generated hydrogen is converted in a fuel cell to provide electricity. The water reactive hydrogen fueled power system includes a fuel cell, a water feed tray, and a fuel cartridge to generate power for portable power electronics. The removable fuel cartridge is encompassed by the water feed tray and fuel cell. The water feed tray is refillable with water by a user. The water is then transferred from the water feed tray into a fuel cartridge to generate hydrogen for the fuel cell which then produces power for the user.

  20. An Automatic Indirect Immunofluorescence Cell Segmentation System

    Directory of Open Access Journals (Sweden)

    Yung-Kuan Chan

    2014-01-01

    Full Text Available Indirect immunofluorescence (IIF with HEp-2 cells has been used for the detection of antinuclear autoantibodies (ANA in systemic autoimmune diseases. The ANA testing allows us to scan a broad range of autoantibody entities and to describe them by distinct fluorescence patterns. Automatic inspection for fluorescence patterns in an IIF image can assist physicians, without relevant experience, in making correct diagnosis. How to segment the cells from an IIF image is essential in developing an automatic inspection system for ANA testing. This paper focuses on the cell detection and segmentation; an efficient method is proposed for automatically detecting the cells with fluorescence pattern in an IIF image. Cell culture is a process in which cells grow under control. Cell counting technology plays an important role in measuring the cell density in a culture tank. Moreover, assessing medium suitability, determining population doubling times, and monitoring cell growth in cultures all require a means of quantifying cell population. The proposed method also can be used to count the cells from an image taken under a fluorescence microscope.

  1. The Smart Energy System

    DEFF Research Database (Denmark)

    Jurowetzki, Roman; Dyrelund, Anders; Hummelmose, Lars

    Copenhagen Cleantech Cluster has launched a new report, which provides an overview of Danish competencies relating to smart energy systems. The report, which is based on a questionnaire answered by almost 200 companies working with smart energy as well as a number of expert interviews, focuses...... on the synergies which are obtained through integration of the district heating and district cooling, gas, and electricity grid into a single smart energy system. Besides documenting the technology and innovation strengths that Danish companies possess particularly relating to wind, district heating, CHP...... production, large scale solar heat, fuel cells, heat storage, waste incineration, among others, the report draws a picture of Denmark as a research and development hub for smart energy system solutions....

  2. An assessment of the present and future opportunities for combined heat and power with district heating (CHP-DH) in the United Kingdom

    International Nuclear Information System (INIS)

    Kelly, Scott; Pollitt, Michael

    2010-01-01

    As global fuel reserves are depleted, alternative and more efficient forms of energy generation and delivery will be required. Combined heat and power with district heating (CHP-DH) provides an alternative energy production and delivery mechanism that is less resource intensive, more efficient and provides greater energy security than many popular alternatives. It will be shown that the economic viability of CHP-DH networks depends on several principles, namely (1) the optimisation of engineering and design principles; (2) organisational and regulatory frameworks; (3) financial and economic factors. It was found that in the long term DH is competitive with other energy supply and distribution technologies such as electricity and gas. However, in the short to medium term it is shown that economic risk, regulatory uncertainty and lock-in of existing technology are the most significant barriers to CHP-DH development. This research suggests that under the present regulatory and economic paradigm, the infrastructure required for DH networks remains financially prohibitive; the implementation of government policies are complicated and impose high transaction costs, while engineering solutions are frequently not implemented or economically optimised. If CHP-DH is going to play any part in meeting climate change targets then collaboration between public and private organisations will be required. It is clear from this analysis that strong local government involvement is therefore necessary for the co-ordination, leadership and infrastructural deployment of CHP-DH.

  3. Cell death in the cardiovascular system

    Science.gov (United States)

    Clarke, Murray; Bennett, Martin; Littlewood, Trevor

    2007-01-01

    Cell death is important for both development and tissue homeostasis in the adult. As such, it is tightly controlled and deregulation is associated with diverse pathologies; for example, regulated cell death is involved in vessel remodelling during development or following injury, but deregulated death is implicated in pathologies such as atherosclerosis, aneurysm formation, ischaemic and dilated cardiomyopathies and infarction. We describe the mechanisms of cell death and its role in the normal physiology and various pathologies of the cardiovascular system. PMID:16547202

  4. Combined heat and power generation with a HCPV system at 2000 suns

    International Nuclear Information System (INIS)

    Paredes, Filippo; Montagnino, Fabio M.; Milone, Sergio; Salinari, Piero; Agnello, Simonpietro; Gelardi, Franco M.; Sciortino, Luisa; Cannas, Marco; Bonsignore, Gaetano; Barbera, Marco; Collura, Alfonso; Lo Cicero, Ugo

    2015-01-01

    This work shows the development of an innovative solar CHP system for the combined production of heat and power based upon HCPV modules working at the high concentration level of 2000 suns. The solar radiation is concentrated on commercial InGaP/InGaAs/Ge triple-junction solar cells designed for intensive work. The primary optics is a rectangular off-axis parabolic mirror while a secondary optic at the focus of the parabolic mirror is glued in optical contact with the cell. Each module consist of 2 axis tracker (Alt-Alt type) with 20 multijunction cells each one integrated with an active heat sink. The cell is connected to an active heat transfer system that allows to keep the cell at a high level of electrical efficiency (ηel > 30 %), bringing the heat transfer fluid (water and glycol) up to an output temperature of 90°C. Accordingly with the experimental data collected from the first 1 kWe prototype, the total amount of extracted thermal energy is above the 50% of the harvested solar radiation. That, in addition the electrical efficiency of the system contributes to reach an overall CHP efficiency of more than the 80%

  5. [Cell polarity in the cardiovascular system].

    Science.gov (United States)

    Haller, C; Kübler, W

    1999-05-01

    The importance of cell polarity as a fundamental biological principle is increasingly recognized in the cardiovascular system. Polar cell mechanisms underlie not only the development of the heart and blood vessels, but also play a major role in the adult organism for polarized endothelial functions such as the separation of the intra- and extravascular compartment and the vectorial exchange of substances between these compartments. Endothelial cells are connected through intercellular junctions which separate the functionally and structurally distinct luminal and abluminal cell surfaces. The luminal plasma membrane is in contact with the blood and takes part in the regulation of hemostasis. The abluminal cell membrane connects the endothelial cell with the basement membrane and modulates blood flow through the release of vasoactive substances. Results from epithelial model systems have shown that the polarized cell phenotype is generated by specific protein sorting and regulated protein trafficking between the trans-Golgi network and the cell surface. The polarized distribution of cell membrane proteins is maintained by anchorage with the cytoskeleton and limitation of lateral diffusion by tight junctions. Disturbances of cell polarity may contribute to the pathogenesis of disease states, including ischemic and radiocontrast-induced acute renal failure and carcinomas. Recent results have demonstrated the importance of cholesterol for protein traffic from the trans-Golgi network to the apical cell membrane. This novel intracellular function of cholesterol could point to a connection between cell polarity and the pathogenesis of arteriosclerosis. The polarity of the endothelium also has to be taken into account when developing gene-therapeutic strategies, since therapeutic success will not only depend on the efficient expression of the desired gene product, but also on its correct cellular location or secretion into the correct extracellular compartment. These

  6. The financial viability of an SOFC cogeneration system in single-family dwellings

    Energy Technology Data Exchange (ETDEWEB)

    Alanne, Kari; Saari, Arto [Department of Civil and Environmental Engineering, Laboratory of Construction Economics and Management, Helsinki University of Technology, P.O. Box 2100, 02015 TKK (Finland); Ugursal, V. Ismet [Department of Mechanical Engineering, University of Victoria, Victoria, BC (Canada); Good, Joel [Department of Environmental Engineering, Dalhousie University, Halifax, Nova Scotia (Canada)

    2006-07-14

    In the near future, fuel cell-based residential micro-CHP systems will compete with traditional methods of energy supply. A micro-CHP system may be considered viable if its incremental capital cost compared to its competitors equals to cumulated savings during a given period of time. A simplified model is developed in this study to estimate the operation of a residential solid oxide fuel cell (SOFC) system. A comparative assessment of the SOFC system vis-a-vis heating systems based on gas, oil and electricity is conducted using the simplified model for a single-family house located in Ottawa and Vancouver. The energy consumption of the house is estimated using the HOT2000 building simulation program. A financial analysis is carried out to evaluate the sensitivity of the maximum allowable capital cost with respect to system sizing, acceptable payback period, energy price and the electricity buyback strategy of an energy utility. Based on the financial analysis, small (1-2kW{sub e}) SOFC systems seem to be feasible in the considered case. The present study shows also that an SOFC system is especially an alternative to heating systems based on oil and electrical furnaces. (author)

  7. Analysing Scenarios of Cell Population System Development

    Directory of Open Access Journals (Sweden)

    M. S. Vinogradova

    2014-01-01

    Full Text Available The article considers an isolated population system consisting of two types of human stem cells, namely normal cells and cells with chromosomal abnormalities (abnormal ones. The system develops in the laboratory (in vitro. The article analyses possible scenarios of the population system development, which are implemented for different values of its parameters. An investigated model of the cell population system takes into account the limited resources. It is represented as a system of two nonlinear differential equations with continuous right-hand part. The model is considered with non-negative values of the variables; the domain is divided into four sets. The model feature is that in each set the right part of the system of differential equations has a different form.The article analyses a quality of the rest points of the system in each of four sets. The analytical conditions for determination of the number of rest points and the quality of rest points, with, at least, one zero coordinate, are obtained.It is shown that the population system under study cannot have more than two points of rest, both coordinates of which are positive (non-zero. It is difficult to determine quality of such rest points depending on the model parameters due to the complexity of the expressions, which define the systems of the first approximation, recorded in a neighborhood of these points of rest. Numerical research results of the stability of these points of rest are obtained, and phase portraits with the specified specific values of the system parameters are demonstrated. The main scenarios for the cell population development are adduced. Analysis of mathematical model shows that a cell population system may remain the system consisting of populations of normal and abnormal cells; it can degenerate into a population of abnormal cells or perish. The scenario, in which there is only the population of normal cells, is not implemented. The numerical simulation

  8. Microbial Heat Recovery Cell (MHRC) System Concept

    Energy Technology Data Exchange (ETDEWEB)

    None

    2017-09-01

    This factsheet describes a project that aimed to develop a microbial heat recovery cell (MHRC) system that combines a microbial reverse electrodialysis technology with waste heat recovery to convert industrial effluents into electricity and hydrogen.

  9. Combined Heat & Power Using the Infinia Concentrated Solar CHP PowerDish System

    Science.gov (United States)

    2013-08-01

    Belen City Hall in New Mexico, Infinia Offices in Washington state, Infinia facility and developmental site in Utah and outside New Delhi, India, as...application. Building #9246 (Figure 6) at Ft. Carson is a 1320 sq ft., single story mobile office unit, set on a concrete foundation, crawlspace...Bldg #9248). There are five cubicles which may be occupied part/full time depending upon the “field work” required at Building #9248 and

  10. Development of a Transient Model of a Stirling-Based CHP System

    OpenAIRE

    Carlos Ulloa; José Luis Míguez; Jacobo Porteiro; Pablo Eguía; Antón Cacabelos

    2013-01-01

    Although the Stirling engine was invented in 1816, this heat engine still continues to be investigated due to the variety of energy sources that can be used to power it (e.g., solar energy, fossil fuels, biomass, and geothermal energy). To study the performance of these machines, it is necessary to develop and simulate models under different operating conditions. In this paper, we present a one-dimensional dynamic model based on components from Trnsys: principally, a lumped mass and a heat ex...

  11. Direct methanol feed fuel cell and system

    Science.gov (United States)

    Surampudi, Subbarao (Inventor); Frank, Harvey A. (Inventor); Narayanan, Sekharipuram R. (Inventor); Chun, William (Inventor); Jeffries-Nakamura, Barbara (Inventor); Kindler, Andrew (Inventor); Halpert, Gerald (Inventor)

    2009-01-01

    Improvements to non acid methanol fuel cells include new formulations for materials. The platinum and ruthenium are more exactly mixed together. Different materials are substituted for these materials. The backing material for the fuel cell electrode is specially treated to improve its characteristics. A special sputtered electrode is formed which is extremely porous. The fuel cell system also comprises a fuel supplying part including a meter which meters an amount of fuel which is used by the fuel cell, and controls the supply of fuel based on said metering.

  12. Intergovernmental Advanced Stationary PEM Fuel Cell System Demonstration Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Rich Chartrand

    2011-08-31

    A program to complete the design, construction and demonstration of a PEMFC system fuelled by Ethanol, LPG or NG for telecom applications was initiated in October 2007. Early in the program the economics for Ethanol were shown to be unfeasible and permission was given by DOE to focus on LPG only. The design and construction of a prototype unit was completed in Jun 2009 using commercially available PEM FC stack from Ballard Power Systems. During the course of testing, the high pressure drop of the stack was shown to be problematic in terms of control and stability of the reformer. Also, due to the power requirements for air compression the overall efficiency of the system was shown to be lower than a similar system using internally developed low pressure drop FC stack. In Q3 2009, the decision was made to change to the Plug power stack and a second prototype was built and tested. Overall net efficiency was shown to be 31.5% at 3 kW output. Total output of the system is 6 kW. Using the new stack hardware, material cost reduction of 63% was achieved over the previous Alpha design. During a November 2009 review meeting Plug Power proposed and was granted permission, to demonstrate the new, commercial version of Plug Power's telecom system at CERL. As this product was also being tested as part of a DOE Topic 7A program, this part of the program was transferred to the Topic 7A program. In Q32008, the scope of work of this program was expanded to include a National Grid demonstration project of a micro-CHP system using hightemperature PEM technology. The Gensys Blue system was cleared for unattended operation, grid connection, and power generation in Aug 2009 at Union College in NY state. The system continues to operate providing power and heat to Beuth House. The system is being continually evaluated and improvements to hardware and controls will be implemented as more is learned about the system's operation. The program is instrumental in improving the

  13. Combined heat and power systems for commercial buildings: investigating cost, emissions, and primary energy reduction based on system components

    Science.gov (United States)

    Smith, Amanda D.

    Combined heat and power (CHP) systems produce electricity and useful heat from fuel. When power is produced near a building which consumes power, transmission losses are averted, and heat which is a byproduct of power production may be useful to the building. That thermal energy can be used for hot water or space heating, among other applications. This dissertation focuses on CHP systems using natural gas, a common fuel, and systems serving commercial buildings in the United States. First, the necessary price difference between purchased electricity and purchased fuel is analyzed in terms of the efficiencies of system components by comparing CHP with a conventional separate heat and power (SHP) configuration, where power is purchased from the electrical grid and heat is provided by a gas boiler. Similarly, the relationship between CDE due to electricity purchases and due to fuel purchases is analyzed as well as the relationship between primary energy conversion factors for electricity and fuel. The primary energy conversion factor indicates the quantity of source energy necessary to produce the energy purchased at the site. Next, greenhouse gas emissions are investigated for a variety of commercial buildings using CHP or SHP. The relationship between the magnitude of the reduction in emissions and the parameters of the CHP system is explored. The cost savings and reduction in primary energy consumption are evaluated for the same buildings. Finally, a CHP system is analyzed with the addition of a thermal energy storage (TES) component, which can store excess thermal energy and deliver it later if necessary. The potential for CHP with TES to reduce cost, emissions, and primary energy consumption is investigated for a variety of buildings. A case study is developed for one building for which TES does provide additional benefits over a CHP system alone, and the requirements for a water tank TES device are examined.

  14. Combined heat and power generation with fuel cells in residential buildings in the future energy system; Kraft-Waerme-Kopplung mit Brennstoffzellen in Wohngebaeuden im zukuenftigen Energiesystem

    Energy Technology Data Exchange (ETDEWEB)

    Jungbluth, C.H.

    2007-04-27

    Combined heat and power generation (CHP) is regarded as one of the cornerstones of a future sustainable energy system. The application of this approach can be substantially extended by employing fuel cell technologies in small units for supplying heat to residential buildings. This could create an additional market for combined heat and power generation corresponding to approx. 25% of the final energy demand in Germany today. In parallel, the extensive application of distributed fuel cell systems in residential buildings would have substantial effects on energy infrastructures, primary energy demand, the energy mix and greenhouse gas emissions. It is the aim of the present study to quantify these effects via scenario modelling of energy demand and supply for Germany up to the year 2050. Two scenarios, reference and ecological commitment, are set up, and the application and operation of fuel cell plants in the future stock of residential buildings is simulated by a bottom-up approach. A model of the building stock was developed for this purpose, consisting of 213 types of reference buildings, as well as detailed simulation models of the plant operation modes. The aim was, furthermore, to identify economically and ecologically optimised plant designs and operation modes for fuel cells in residential buildings. Under the assumed conditions of the energy economy, economically optimised plant sizes for typical one- or two-family homes are in the range of a generating capacity of a few hundred watts of electrical power. Plant sizes of 2 to 4.7 kW{sub el} as discussed today are only economically feasible in multifamily dwellings. The abolition of the CHP bonus reduces profitability, especially for larger plants operated by contractors. In future, special strategies for power generation and supply can be an economically useful addition for the heat-oriented operation mode of fuel cells. On the basis of the assumed conditions of the energy economy, a technical potential for

  15. Thermodynamic simulation analysis of a multifuel CHP plant basing on the technological diagram of Avedøre unit 2

    Science.gov (United States)

    Ziębik, Andrzej; Szegda, Damian; Qvale, Bjørn; Elmegaard, Brian

    2010-03-01

    The paper presents the results of a simulative thermodynamic analysis of a multifuel CHP plant basing on the technological diagram of Avedøre 2. Calculations have been carried out for the operation of Avedøre 2 plant in the district heating mode. Several variants of simulation have been considered, determined by the choice of operation of the respective plants, viz. main boiler fired with natural gas, main and biomass boiler, main boiler and GT plant, joint operation of the main and biomass boiler and GT plant, main boiler (fired with heavy fuel oil or/and wood chips) and biomass boiler and GT plant. For each variants a diagram of iso-fuel curves has been developed, illustrating the variability of useful effects (power output and district heat) at various loads of the CHP steam part. In case of the variant in which the main boiler and GT are in operation with natural gas as fuel the exemplary energy indices were determined.

  16. In-situ corrosion investigation at Masnedø CHP plant - a straw-fired power plant

    DEFF Research Database (Denmark)

    Montgomery, Melanie; Karlsson, Asger

    1999-01-01

    Various austenitic and ferritic steels were exposed on a water-cooled probe in the superheater area of a straw-fired CHP plant. The temperature of the probe ranged from 450-600°C and the period of exposure was 1400 hours. The rate of corrosion was assessed based on unattacked metal remaining. The...... in depletion of chromium from the alloy. A clear trend was observed that selective corrosion increased with respect to the chromium content of the alloy.......Various austenitic and ferritic steels were exposed on a water-cooled probe in the superheater area of a straw-fired CHP plant. The temperature of the probe ranged from 450-600°C and the period of exposure was 1400 hours. The rate of corrosion was assessed based on unattacked metal remaining....... The corrosion products and course of corrosion for the various steel types were investigated using light optical and scanning electron microscopy. The ferritic steels suffered from corrosion mainly via material loss. The austenitic steels suffered from predominantly selective corrosion which resulted...

  17. Carbon Debt Payback Time for a Biomass Fired CHP Plant—A Case Study from Northern Europe

    Directory of Open Access Journals (Sweden)

    Kristian Madsen

    2018-03-01

    Full Text Available The European Union (EU has experienced a large increase in the use of biomass for energy in the last decades. In 2015, biomass used to generate electricity, heat, and to a limited extent, liquid fuels accounted for 51% of the EU’s renewable energy production. Bioenergy use is expected to grow substantially to meet energy and climate targets for 2020 and beyond. This development has resulted in analyses suggesting the increased use of biomass for energy might initially lead to increased greenhouse gas (GHG emissions to the atmosphere, a so-called carbon debt. Here, we analyze carbon debt and payback time of substituting coal with forest residues for combined heat and power generation (CHP. The analysis is, in contrast to most other studies, based on empirical data from a retrofit of a CHP plant in northern Europe. The results corroborate findings of a carbon debt, here 4.4 kg CO2eq GJ−1. The carbon debt has a payback time of one year after conversion, and furthermore, the results show that GHG emissions are reduced to 50% relative to continued coal combustion after about 12 years. The findings support the use of residue biomass for energy as an effective means for climate change mitigation.

  18. Foetal Leydig cells and the neuroendocrine system.

    Science.gov (United States)

    Sklebar, Duska; Semanjski, Kristina; Kos, Marina; Sklebar, Ivan; Jezek, Davor

    2008-01-01

    It has been shown that adult human Leydig cells express a number of neuroendocrine markers, and, therefore, could be considered as a part of the neuroendocrine system in the adult. A limited number of studies have dealt with the dynamics of development of human foetal Leydig cells, whereas studies on their neuroendocrine nature are still extremely rare. Therefore, the aim of our study was to investigate the development of human foetal Leydig cells in different weeks of gestation (wg) and to check if these cells express certain markers characteristic of the diffuse neuroendocrine system (DNS). Qualitative, quantitative histological studies and immunohistochemical analyses of human foetal testicular tissue have been performed. According to our data, Leydig cells formed a dynamic population of cells within the interstitum of testes in the period between 15 and 36 wg. The total number of Leydig cells of human foetal testes changed through different stages of gestation by means of 'pulsatile' dynamics (most likely, by following the variable level of gonadotropins). At early stages of development (15-17 wg) immunohistochemical reactions for the expression of neuron specific enolase (NSE) were positive within sex cords and between them, in the interstitum. Pro-spermatogonia in the sex cords were positive, as well as elongated spindle-shaped cells of the interstitum (very likely, precursors of Leydig cells). During the later stages of development (28-36 wg), excluding the pro-spermatogonia, the interstitial Leydig cells were also positive. The results of the immunohistochemical analyses (the expression of NSE) confirmed the hypothesis that human foetal Leydig cells were of neuroendocrine nature.

  19. Glial Cells: The Other Cells of the Nervous System

    Indian Academy of Sciences (India)

    Carl Ludwig Schleich (1859-1922) was an anaesthetist and a surgeon who for the first time emphasized the role of neuroglia in brain function. In an era that was dominated by the idea that neurons alone were functional units of the nervous system and that glial cells were a mere glue holding neurons in place, Schleich ...

  20. New Polymer Electrolyte Cell Systems

    Science.gov (United States)

    Smyrl, William H.; Owens, Boone B.; Mann, Kent; Pappenfus, T.; Henderson, W.

    2004-01-01

    PAPERS PUBLISHED: 1. Pappenfus, Ted M.; Henderson, Wesley A.; Owens, Boone B.; Mann, Kent R.; Smyrl, William H. Complexes of Lithium Imide Salts with Tetraglyme and Their Polyelectrolyte Composite Materials. Journal of the Electrochemical Society (2004), 15 1 (2), A209-A2 15. 2. Pappenfus, Ted M.; Henderson, Wesley A.; Owens, Boone B.; Mann, Kent R.; Smyrl, William H. Ionic-liquidlpolymer electrolyte composite materials for electrochemical device applications. Polymeric Materials Science and Engineering (2003), 88 302. 3. Pappenfus, Ted R.; Henderson, Wesley A.; Owens, Boone B.; Mann, Kent R.; and Smyrl, William H. Ionic Conductivity of a poly(vinylpyridinium)/Silver Iodide Solid Polymer Electrolyte System. Solid State Ionics (in press 2004). 4. Pappenfus Ted M.; Mann, Kent R; Smyrl, William H. Polyelectrolyte Composite Materials with LiPFs and Tetraglyme. Electrochemical and Solid State Letters, (2004), 7(8), A254.

  1. Development and analysis of micro-polygeneration systems and adsorption chillers

    Science.gov (United States)

    Gluesenkamp, Kyle

    About a fifth of all primary energy in the US is consumed by residential buildings, mostly for cooling, heating and to provide electricity. Furthermore, retrofits are essential to reducing this consumption, since the buildings that exist today will comprise over half of those in use in 2050. Residential combined heat and power (or micro CHP, defined by off-grid for today's prime movers, with potential on-grid for various fuel cell technologies. A novel dynamic test facility was developed to measure real-world residential trigeneration system performance using a prototype adsorption chiller. The chiller was designed and constructed for this thesis and was driven by waste heat from a commercially available natural gas-fueled 4 kW (electric) CHP engine. A control strategy for the chiller was developed, enabling a 5-day experiment to be run using a thermal load profile based on moderate Maryland summer air conditioning loads and typical single-family domestic hot water demand, with experimental results in agreement with models. In this summer mode, depending on electrical loads, the trigeneration system used up to 36% less fuel than off-grid separate generation and up to 29% less fuel than off-grid CHP without thermally driven cooling. However, compared to on-grid separate generation, the experimental facility used 16% more primary energy. Despite high chiller performance relative to its thermodynamic limit, this result is primarily due to the electrical efficiency of the prime mover being lower than the grid. A residential trigeneration system utilizing a high temperature fuel cell is predicted to save up to 42% primary energy relative to the grid.

  2. Redox flow cell energy storage systems

    Science.gov (United States)

    Thaller, L. H.

    1979-01-01

    NASA-Redox systems are electrochemical storage devices that use two fully soluble Redox couples, anode and cathode fluids, as active electrode materials separated by a highly selective ion exchange membrane. The reactants are contained in large storage tanks and pumped through a stack of Redox flow cells where the electrochemical reactions (reduction and oxidation) take place at porous carbon felt electrodes. A string or stack of these power producing cells is connected in series in a bipolar manner. Redox energy storage systems promise to be inexpensive and possess many features that provide for flexible design, long life, high reliability and minimal operation and maintenance costs. These features include independent sizing of power and storage capacity requirements and inclusion within the cell stack of a cell that monitors the state of charge of the system as a whole, and a rebalance cell which permits continuous correction to be made for minor side reactions that would tend to result in the anode fluid and cathode fluids becoming electrochemically out of balance. These system features are described and discussed.

  3. Cooling Grapple System for FMEF hot cell

    International Nuclear Information System (INIS)

    Semmens, L.S.; Frandsen, G.B.; Tome, R.

    1983-01-01

    A Cooling Grapple System was designed and built to handle fuel assemblies within the FMEF hot cell. The variety of functions for which it is designed makes it unique from grapples presently in use. The Cooling Grapple can positively grip and transport assemblies vertically, retrieve assemblies from molten sodium where six inches of grapple tip is submerged, cool 7 kw assemblies in argon, and service an in-cell area of 372 m 2 (4000 ft 2 ). Novel and improved operating and maintenance features were incorporated in the design including a shear pin and mechanical catcher system to prevent overloading the grapple while allowing additional reaction time for crane shutdown

  4. High throughput solar cell ablation system

    Science.gov (United States)

    Harley, Gabriel; Pass, Thomas; Cousins, Peter John; Viatella, John

    2012-09-11

    A solar cell is formed using a solar cell ablation system. The ablation system includes a single laser source and several laser scanners. The laser scanners include a master laser scanner, with the rest of the laser scanners being slaved to the master laser scanner. A laser beam from the laser source is split into several laser beams, with the laser beams being scanned onto corresponding wafers using the laser scanners in accordance with one or more patterns. The laser beams may be scanned on the wafers using the same or different power levels of the laser source.

  5. Glial Cells: The Other Cells of the Nervous System-Schwann Cells ...

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 7; Issue 8. Glial Cells: The Other Cells of the Nervous System - Schwann Cells – Regulators of the Periphery. Yasmin Khan Medha S Rajadhyaksha. Series Article Volume 7 Issue 8 August 2002 pp 8-15 ...

  6. Flexible energy systems

    DEFF Research Database (Denmark)

    Lund, Henrik

    2003-01-01

    The paper discusses and analyses diffent national strategies and points out key changes in the energy system in order to achieve a system which can benefit from a high percentage of wind and CHP without having surplus production problems, introduced here as a flexible energy system....

  7. Integrated energy markets and varying degrees of liberalisation: Price links, bundled sales and CHP production exemplified by Northern European experiences

    International Nuclear Information System (INIS)

    Klinge Jacobsen, Henrik; Fristrup, Peter; Munksgaard, Jesper

    2006-01-01

    Liberalisation of energy markets has during the last 20 years been gradually introduced in many countries. The liberalisation has led to concerns regarding the markets' state of competition and fears that market power existence can result in less efficiency gains than what is expected from liberalisation. Concerns have also been raised as to whether specific consumer groups will be affected by limited competition in markets. Much of the concern has been concentrated on the electricity markets, but the development of energy sectors with integration of activities within natural gas, electricity and the oil sector creates the need to examine market power aspects across these markets. This paper examines the concentration trends in the Northern European markets for electricity and natural gas, combined with regional district heating aspects, especially with respect to the situation in Denmark. The situation with natural gas companies supplying to both small-scale CHP and to retail heat customers is discussed, for instance, which changes of regulatory regime for domestic heating customers should be considered when the natural gas market is being liberalised? The interlinked nature of the energy markets is described and examples of impacts from one market with limited competition to other markets with seemingly well-functioning competition are given. The specific case of large CHP production facilities with output on the regulated district heating market and the competitive Nordic electricity market is examined. How much of the fluctuations in price experienced in electricity markets should be reflected in the price of heating supplies? To which degree do the heating customers have to bear the burden of low-electricity market prices? Regulation of liberalised markets is discussed focusing on the interaction between one regulated market and the related energy markets that are liberalised. Existing regulation on the markets are compared to a situation where liberalisation

  8. Integrated energy markets and varying degrees of liberalisation: price links, bundled sales and CHP production exemplified by Northern European experiences

    International Nuclear Information System (INIS)

    Jacobsen, H.K.; Fristrup, P.; Munksgaard, J.

    2006-01-01

    Liberalisation of energy markets has during the last 20 years been gradually introduced in many countries. The liberalisation has led to concerns regarding the markets' state of competition and fears that market power existence can result in less efficiency gains than what is expected from liberalisation. Concerns have also been raised as to whether specific consumer groups will be affected by limited competition in markets. Much of the concern has been concentrated on the electricity markets, but the development of energy sectors with integration of activities within natural gas, electricity and the oil sector creates the need to examine market power aspects across these markets. This paper examines the concentration trends in the Northern European markets for electricity and natural gas, combined with regional district heating aspects, especially with respect to the situation in Denmark. The situation with natural gas companies supplying to both small-scale CHP and to retail heat customers is discussed, for instance, which changes of regulatory regime for domestic heating customers should be considered when the natural gas market is being liberalised? The interlinked nature of the energy markets is described and examples of impacts from one market with limited competition to other markets with seemingly well-functioning competition are given. The specific case of large CHP production facilities with output on the regulated district heating market and the competitive Nordic electricity market is examined. How much of the fluctuations in price experienced in electricity markets should be reflected in the price of heating supplies? To which degree do the heating customers have to bear the burden of low-electricity market prices? Regulation of liberalised markets is discussed focusing on the interaction between one regulated market and the related energy markets that are liberalised. Existing regulation on the markets are compared to a situation where liberalisation

  9. Fuel cell system for transportation applications

    Science.gov (United States)

    Kumar, Romesh; Ahmed, Shabbir; Krumpelt, Michael; Myles, Kevin M.

    1993-01-01

    A propulsion system for a vehicle having pairs of front and rear wheels and a fuel tank. An electrically driven motor having an output shaft operatively connected to at least one of said pair of wheels is connected to a fuel cell having a positive electrode and a negative electrode separated by an electrolyte for producing dc power to operate the motor. A partial oxidation reformer is connected both to the fuel tank and to the fuel cell receives hydrogen-containing fuel from the fuel tank and water and air and for partially oxidizing and reforming the fuel with water and air in the presence of an oxidizing catalyst and a reforming catalyst to produce a hydrogen-containing gas. The hydrogen-containing gas is sent from the partial oxidation reformer to the fuel cell negative electrode while air is transported to the fuel cell positive electrode to produce dc power for operating the electric motor.

  10. Onion root tip cell system for biodosimetry?

    International Nuclear Information System (INIS)

    Paradiz, J; Druskovic, B.; Lovka, M.; Skrk, J.

    1996-01-01

    Methodology for radiation dose assessment based on chromosomal damage to plant cells has no yet been established, although root meristems have been the pioneer cytogenetic materials and profound analyses of irradiated meristematic cells of horse bean (Viciafaba L.) had been performed. Onion (Allium cepa L.) root tips frequently used for radiation cytogenetic studies, are recently considered to be one of the most promising plant test system for the detection of genotoxic environmental pollutants. We studied the possibility of using cytogenetic analyses of irradiated onion cells to determine the effective biological dose of ionizing radiation. The dose-effect relationships for chromosomal damages to onion meristematic cells were established after plants had been irradiated and subsequently grown in both laboratory and field conditions

  11. Measuring cell identity in noisy biological systems

    Science.gov (United States)

    Birnbaum, Kenneth D.; Kussell, Edo

    2011-01-01

    Global gene expression measurements are increasingly obtained as a function of cell type, spatial position within a tissue and other biologically meaningful coordinates. Such data should enable quantitative analysis of the cell-type specificity of gene expression, but such analyses can often be confounded by the presence of noise. We introduce a specificity measure Spec that quantifies the information in a gene's complete expression profile regarding any given cell type, and an uncertainty measure dSpec, which measures the effect of noise on specificity. Using global gene expression data from the mouse brain, plant root and human white blood cells, we show that Spec identifies genes with variable expression levels that are nonetheless highly specific of particular cell types. When samples from different individuals are used, dSpec measures genes’ transcriptional plasticity in each cell type. Our approach is broadly applicable to mapped gene expression measurements in stem cell biology, developmental biology, cancer biology and biomarker identification. As an example of such applications, we show that Spec identifies a new class of biomarkers, which exhibit variable expression without compromising specificity. The approach provides a unifying theoretical framework for quantifying specificity in the presence of noise, which is widely applicable across diverse biological systems. PMID:21803789

  12. Coal Integrated Gasification Fuel Cell System Study

    Energy Technology Data Exchange (ETDEWEB)

    Chellappa Balan; Debashis Dey; Sukru-Alper Eker; Max Peter; Pavel Sokolov; Greg Wotzak

    2004-01-31

    This study analyzes the performance and economics of power generation systems based on Solid Oxide Fuel Cell (SOFC) technology and fueled by gasified coal. System concepts that integrate a coal gasifier with a SOFC, a gas turbine, and a steam turbine were developed and analyzed for plant sizes in excess of 200 MW. Two alternative integration configurations were selected with projected system efficiency of over 53% on a HHV basis, or about 10 percentage points higher than that of the state-of-the-art Integrated Gasification Combined Cycle (IGCC) systems. The initial cost of both selected configurations was found to be comparable with the IGCC system costs at approximately $1700/kW. An absorption-based CO2 isolation scheme was developed, and its penalty on the system performance and cost was estimated to be less approximately 2.7% and $370/kW. Technology gaps and required engineering development efforts were identified and evaluated.

  13. Stem cells and the aging hematopoietic system.

    Science.gov (United States)

    Beerman, Isabel; Maloney, William J; Weissmann, Irving L; Rossi, Derrick J

    2010-08-01

    Advancing age is accompanied by a number of clinically significant conditions arising in the hematopoietic system that include: diminution and decreased competence of the adaptive immune system, elevated incidence of certain autoimmune diseases, increased hematological malignancies, and elevated incidence of age-associated anemia. As with most tissues, the aged hematopoietic system also exhibits a reduced capacity to regenerate and return to normal homeostasis after injury or stress. Evidence suggests age-dependent functional alterations within the hematopoietic stem cell compartment significantly contribute to many of these pathophysiologies. Recent developments have shed light on how aging of the hematopoietic stem cell compartment contributes to hematopoietic decline through diverse mechanisms. Copyright 2010 Elsevier Ltd. All rights reserved.

  14. The method of the unit costs. A method for CHP plants cost allocation on both types of energy

    International Nuclear Information System (INIS)

    Ruieneanu, Liviu; Ion, Mircea; Ion, Mircea

    2004-01-01

    In the first part of the paper we try to explain why the production of electricity is more expansive than the production of heat. In the last part of the paper we propose a new method for fuel consumption allocation between the two forms of energy. The method leads to a scientifically higher cost for electricity but on the other hand presents some important advantages: - It establishes a correct price for both types of energy, increasing the competitiveness of the CHP plant on the heat market; - It facilitates the implementation of the energy efficiency methods focusing on electricity savings and that leads to higher fuel savings and lower greenhouse gasses emissions; - It facilitates the rehabilitation methods that lead to a higher electricity production efficiency

  15. Financial appraisal of a combined heat and power system for a hotel in Cyprus

    Energy Technology Data Exchange (ETDEWEB)

    Papamarcou, M.; Kalogirou, S. [Higher Technical Inst., Nicosia, Cyprus (Greece)

    2001-04-01

    A combined heat and power (CHP) system can convert low cost fuel, such as gas or fuel oil, into high value electricity and heat. It can generate ''home-made'' electricity more cheaply than it can be purchased. The term CHP is used to define the process of utilising the plant to generate both electricity and heat simultaneously, thereby extracting a greater benefit from the fuel used. In this work, a feasibility study of a CHP system for a hotel application is presented. The Cyprus energy scene is presented, followed by an energy analysis of the hotel. A description of the CHP system is also presented. The method of economic analysis adopted in this study is the discounted cash flow method, which takes into account the time value of money. The analysis is conducted with the use of a spreadsheet program. The economic analysis of the CHP system shows that the annual net saving of the system is around Cy 26,500 pounds, while the capital investment is Cy85,000 pounds. The payback period of the system is found to be 3.2 years, which is very satisfactory. Based on the findings presented in this paper, it is believed that CHP is viable for the Cyprus hotel industry. (author)

  16. High performance liquid chromatographic separation of thirteen drugs collected in Chinese Pharmacopoeia 2010(Ch.P2010 on cellulose ramification chiral stationary phase

    Directory of Open Access Journals (Sweden)

    Ying Zhou

    2012-02-01

    Full Text Available The enantiomers separation of thirteen drugs collected in Ch.P2010 was performed on chiral stationary phase of cellulose ramification (chiralpak OD and chiralpak OJ by high performance liquid chromatographic (HPLC methods, which included ibuprofen (C1, ketoprofen (C2, nitrendipine (C3, nimodipine (C4, felodipine (C5, omeprazole (C6, praziquantel (C7, propranolol hydrochloride (C8, atenolol (C9, sulpiride (C10, clenbuterol hydrochloride (C11, verapamil hydrochloride (C12, and chlorphenamine maleate (C13. The mobile phase consisted of isopropanol and n-hexane. The detection wavelength was set at 254 nm and the flow rate was 0.7 mL/min. The enantiomers separation of these thirteen racemates on chiralpak OD column and chiralpak OJ column was studied, while the effects of proportion of organic additives, alcohol displacer and temperature on the separation were studied. And the mechanism of some of racemates was discussed. The results indicated that thirteen chiral drugs could be separated on chiral stationary phase of cellulose ramification in normal phase chromatographic system. The chromatographic retention and resolution of enantiomers could be adjusted by factors including column temperature and the concentration of alcohol displacer and organic alkaline modifier in mobile phase. It was shown that the resolution was improved with reducing concentration of alcohol displacer. When concentration of organic alkaline modifier was 0.2% (v/v, the resolution and the peak shape were fairly good. Most racemates mentioned above had better resolution at column temperature of 25 °C. When racemates were separated, the temperature should be kept so as to obtain stable separation results. Keywords: HPLC, Chiral stationary phase, Optical enantiomers, Cellulose ramification

  17. Energy Saving and GHG Emission Reduction in a Micro-CCHP System by Use of Solar Energy

    OpenAIRE

    Ion, I; Ciocea, G; Popescu, F

    2012-01-01

    In this work, the reduction of greenhouse gas emission, and the energy saving by integrating solar collectors and photovoltaic panels in a Stirling engine based microcombined cooling, heating and power (mCCHP) system are studied. The mCCHP system consists of a natural gas Stirling CHP and an adsorber chiller. When the thermal outputs of the Stirling CHP and solar collectors are not sufficient to cover the heat demand for domestic hot water (DHW), heating/cooling, an au...

  18. Solid Oxide Fuel Cell Systems PVL Line

    International Nuclear Information System (INIS)

    Shearer, Susan; Rush, Gregory

    2012-01-01

    In July 2010, Stark State College (SSC), received Grant DE-EE0003229 from the U.S. Department of Energy (DOE), Golden Field Office, for the development of the electrical and control systems, and mechanical commissioning of a unique 20kW scale high-pressure, high temperature, natural gas fueled Stack Block Test System (SBTS). SSC worked closely with subcontractor, Rolls-Royce Fuel Cell Systems (US) Inc. (RRFCS) over a 13 month period to successfully complete the project activities. This system will be utilized by RRFCS for pre-commercial technology development and training of SSC student interns. In the longer term, when RRFCS is producing commercial products, SSC will utilize the equipment for workforce training. In addition to DOE Hydrogen, Fuel Cells, and Infrastructure Technologies program funding, RRFCS internal funds, funds from the state of Ohio, and funding from the DOE Solid State Energy Conversion Alliance (SECA) program have been utilized to design, develop and commission this equipment. Construction of the SBTS (mechanical components) was performed under a Grant from the State of Ohio through Ohio's Third Frontier program (Grant TECH 08-053). This Ohio program supported development of a system that uses natural gas as a fuel. Funding was provided under the Department of Energy (DOE) Solid-state Energy Conversion Alliance (SECA) program for modifications required to test on coal synthesis gas. The subject DOE program provided funding for the electrical build, control system development and mechanical commissioning. Performance testing, which includes electrical commissioning, was subsequently performed under the DOE SECA program. Rolls-Royce Fuel Cell Systems is developing a megawatt-scale solid oxide fuel cell (SOFC) stationary power generation system. This system, based on RRFCS proprietary technology, is fueled with natural gas, and operates at elevated pressure. A critical success factor for development of the full scale system is the capability to

  19. Effects of the distribution density of a biomass combined heat and power plant network on heat utilisation efficiency in village-town systems.

    Science.gov (United States)

    Zhang, Yifei; Kang, Jian

    2017-11-01

    The building of biomass combined heat and power (CHP) plants is an effective means of developing biomass energy because they can satisfy demands for winter heating and electricity consumption. The purpose of this study was to analyse the effect of the distribution density of a biomass CHP plant network on heat utilisation efficiency in a village-town system. The distribution density is determined based on the heat transmission threshold, and the heat utilisation efficiency is determined based on the heat demand distribution, heat output efficiency, and heat transmission loss. The objective of this study was to ascertain the optimal value for the heat transmission threshold using a multi-scheme comparison based on an analysis of these factors. To this end, a model of a biomass CHP plant network was built using geographic information system tools to simulate and generate three planning schemes with different heat transmission thresholds (6, 8, and 10 km) according to the heat demand distribution. The heat utilisation efficiencies of these planning schemes were then compared by calculating the gross power, heat output efficiency, and heat transmission loss of the biomass CHP plant for each scenario. This multi-scheme comparison yielded the following results: when the heat transmission threshold was low, the distribution density of the biomass CHP plant network was high and the biomass CHP plants tended to be relatively small. In contrast, when the heat transmission threshold was high, the distribution density of the network was low and the biomass CHP plants tended to be relatively large. When the heat transmission threshold was 8 km, the distribution density of the biomass CHP plant network was optimised for efficient heat utilisation. To promote the development of renewable energy sources, a planning scheme for a biomass CHP plant network that maximises heat utilisation efficiency can be obtained using the optimal heat transmission threshold and the nonlinearity

  20. Sensor Development for PEM Fuel Cell Systems

    Energy Technology Data Exchange (ETDEWEB)

    Steve Magee; Richard Gehman

    2005-07-12

    This document reports on the work done by Honeywell Sensing and Control to investigate the feasibility of modifying low cost Commercial Sensors for use inside a PEM Fuel Cell environment. Both stationary and automotive systems were considered. The target environment is hotter (100 C) than the typical commercial sensor maximum of 70 C. It is also far more humid (100% RH condensing) than the more typical 95% RH non-condensing at 40 C (4% RH maximum at 100 C). The work focused on four types of sensors, Temperature, Pressure, Air Flow and Relative Humidity. Initial design goals were established using a market research technique called Market Driven Product Definition (MDPD). A series of interviews were conducted with various users and system designers in their facilities. The interviewing team was trained in data taking and analysis per the MDPD process. The final result was a prioritized and weighted list of both requirements and desires for each sensor. Work proceeded on concept development for the 4 types of sensors. At the same time, users were developing the actual fuel cell systems and gaining knowledge and experience in the use of sensors and controls systems. This resulted in changes to requirements and desires that were not anticipated during the MDPD process. The concepts developed met all the predicted requirements. At the completion of concept development for the Pressure Sensor, it was determined that the Fuel Cell developers were happy with off-the-shelf automotive pressure sensors. Thus, there was no incentive to bring a new Fuel Cell Specific Pressure Sensor into production. Work was therefore suspended. After the experience with the Pressure Sensor, the requirements for a Temperature Sensor were reviewed and a similar situation applied. Commercially available temperature sensors were adequate and cost effective and so the program was not continued from the Concept into the Design Phase.

  1. Robust Management of Combined Heat and Power Systems via Linear Decision Rules

    DEFF Research Database (Denmark)

    Zugno, Marco; Morales González, Juan Miguel; Madsen, Henrik

    2014-01-01

    The heat and power outputs of Combined Heat and Power (CHP) units are jointly constrained. Hence, the optimal management of systems including CHP units is a multicommodity optimization problem. Problems of this type are stochastic, owing to the uncertainty inherent both in the demand for heat and...... linear decision rules to guarantee both tractability and a correct representation of the dynamic aspects of the problem. Numerical results from an illustrative example confirm the value of the proposed approach....

  2. Design and Optimization of an Integrated Biomass Gasification and Solid Oxide Fuel Cell System

    DEFF Research Database (Denmark)

    Bang-Møller, Christian

    based on biomass will improve the competitiveness of decentralized CHP production from biomass as well as move the development towards a more sustainable CHP production. The aim of this research is to contribute to enhanced electrical efficiencies and sustainability in future decentralized CHP plants......-level modelling study of three conceptual plant designs based on two-stage gasification of wood chips with a thermal biomass input of ~0.5 MWth (LHV) is presented. Product gas is converted in a micro gas turbine (MGT) in the first plant design, in SOFCs in the second, and in a combined SOFC-MGT arrangement......Development of sustainable power plants has gained focus in the recent years and utilization of biomass resources are seen as a pathway towards a sustainable combined heat and power (CHP) production. Biomass resources are distributed, thus decentralized biomass conversion would avoid extensive cost...

  3. Expanding photovoltaic penetration with residential distributed generation from hybrid solar photovoltaic and combined heat and power systems

    International Nuclear Information System (INIS)

    Pearce, J.M.

    2009-01-01

    The recent development of small scale combined heat and power (CHP) systems has provided the opportunity for in-house power backup of residential-scale photovoltaic (PV) arrays. This paper investigates the potential of deploying a distributed network of PV + CHP hybrid systems in order to increase the PV penetration level in the U.S. The temporal distribution of solar flux, electrical and heating requirements for representative U.S. single family residences were analyzed and the results clearly show that hybridizing CHP with PV can enable additional PV deployment above what is possible with a conventional centralized electric generation system. The technical evolution of such PV + CHP hybrid systems was developed from the present (near market) technology through four generations, which enable high utilization rates of both PV-generated electricity and CHP-generated heat. A method to determine the maximum percent of PV-generated electricity on the grid without energy storage was derived and applied to an example area. The results show that a PV + CHP hybrid system not only has the potential to radically reduce energy waste in the status quo electrical and heating systems, but it also enables the share of solar PV to be expanded by about a factor of five. (author)

  4. Design of a thermally integrated bioethanol-fueled solid oxide fuel cell system integrated with a distillation column

    Science.gov (United States)

    Jamsak, W.; Douglas, P. L.; Croiset, E.; Suwanwarangkul, R.; Laosiripojana, N.; Charojrochkul, S.; Assabumrungrat, S.

    Solid oxide fuel cell systems integrated with a distillation column (SOFC-DIS) have been investigated in this study. The MER (maximum energy recovery) network for SOFC-DIS system under the base conditions (C EtOH = 25%, EtOH recovery = 80%, V = 0.7 V, fuel utilization = 80%, T SOFC = 1200 K) yields Q Cmin = 73.4 and Q Hmin = 0 kW. To enhance the performance of SOFC-DIS, utilization of internal useful heat sources from within the system (e.g. condenser duty and hot water from the bottom of the distillation column) and a cathode recirculation have been considered in this study. The utilization of condenser duty for preheating the incoming bioethanol and cathode recirculation for SOFC-DIS system were chosen and implemented to the SOFC-DIS (CondBio-CathRec). Different MER designs were investigated. The obtained MER network of CondBio-CathRec configuration shows the lower minimum cold utility (Q Cmin) of 55.9 kW and total cost index than that of the base case. A heat exchanger loop and utility path were also investigated. It was found that eliminate the high temperature distillate heat exchanger can lower the total cost index. The recommended network is that the hot effluent gas is heat exchanged with the anode heat exchanger, the external reformer, the air heat exchanger, the distillate heat exchanger and the reboiler, respectively. The corresponding performances of this design are 40.8%, 54.3%, 0.221 W cm -2 for overall electrical efficiency, Combine Heat and Power (CHP) efficiency and power density, respectively. The effect of operating conditions on composite curves on the design of heat exchanger network was investigated. The obtained composite curves can be divided into two groups: the threshold case and the pinch case. It was found that the pinch case which T SOFC = 1173 K yields higher total cost index than the CondBio-CathRec at the base conditions. It was also found that the pinch case can become a threshold case by adjusting split fraction or operating at

  5. Advanced manipulator system for large hot cells

    International Nuclear Information System (INIS)

    Vertut, J.; Moreau, C.; Brossard, J.P.

    1981-01-01

    Large hot cells can be approached as extrapolated from smaller ones as wide, higher or longer in size with the same concept of using mechanical master slave manipulators and high density windows. This concept leads to a large number of working places and corresponding equipments, with a number of penetrations through the biological protection. When the large cell does not need a permanent operation of number of work places, as in particular to serve PIE machines and maintain the facility, use of servo manipulators with a large supporting unit and extensive use of television appears optimal. The advance on MA 23 and supports will be described including the extra facilities related to manipulators introduction and maintenance. The possibility to combine a powered manipulator and MA 23 (single or pair) on the same boom crane system will be described. An advance control system to bring the minimal dead time to control support movement, associated to the master slave arm operation is under development. The general television system includes over view cameras, associated with the limited number of windows, and manipulators camera. A special new system will be described which brings an automatic control of manipulator cameras and saves operator load and dead time. Full scale tests with MA 23 and support will be discussed. (author)

  6. Translation in cell-free systems

    International Nuclear Information System (INIS)

    Jagus, R.

    1987-01-01

    The simplest, unambiguous identification of a particular mRNA is the identification of its protein product. This can be established by translation of the mRNA of interest in a cell-free protein-synthesizing system. Messenger RNA protein product identification is important in the isolation of a particular mRNA species for cDNA cloning and in the identification of positive cDNA clones. The two high-activity translation systems in common use are those prepared from rabbit reticulocytes and from wheat germ. Both systems are easy to prepare, and both are available commercially. Each has advantages and disadvantages over the other and a choice between the two will depend on the type of mRNAs to be translated, the prejudices of experience, and availability. The main disadvantage of the reticulocyte system is that it requires removal of endogenous mRNA. However, this is a relatively simple procedure. The wheat germ system does not require removal of endogenous mRNA and may translate weakly initiating mRNAs more efficiently. However, ionic optima for translation in the wheat germ system are more sensitive to the nature and concentration of mRNA and may need to be determined for each template. The biggest problem with the use of the wheat germ system is its tendency to produce incomplete translation products due to premature termination

  7. Analysis of Fuel Cell Markets in Japan and the US: Experience Curve Development and Cost Reduction Disaggregation

    Energy Technology Data Exchange (ETDEWEB)

    Wei, Max [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Smith, Sarah J. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Sohn, Michael D. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2016-07-15

    Fuel cells are both a longstanding and emerging technology for stationary and transportation applications, and their future use will likely be critical for the deep decarbonization of global energy systems. As we look into future applications, a key challenge for policy-makers and technology market forecasters who seek to track and/or accelerate their market adoption is the ability to forecast market costs of the fuel cells as technology innovations are incorporated into market products. Specifically, there is a need to estimate technology learning rates, which are rates of cost reduction versus production volume. Unfortunately, no literature exists for forecasting future learning rates for fuel cells. In this paper, we look retrospectively to estimate learning rates for two fuel cell deployment programs: (1) the micro-combined heat and power (CHP) program in Japan, and (2) the Self-Generation Incentive Program (SGIP) in California. These two examples have a relatively broad set of historical market data and thus provide an informative and international comparison of distinct fuel cell technologies and government deployment programs. We develop a generalized procedure for disaggregating experience-curve cost-reductions in order to disaggregate the Japanese fuel cell micro-CHP market into its constituent components, and we derive and present a range of learning rates that may explain observed market trends. Finally, we explore the differences in the technology development ecosystem and market conditions that may have contributed to the observed differences in cost reduction and draw policy observations for the market adoption of future fuel cell technologies. The scientific and policy contributions of this paper are the first comparative experience curve analysis of past fuel cell technologies in two distinct markets, and the first quantitative comparison of a detailed cost model of fuel cell systems with actual market data. The resulting approach is applicable to

  8. Solid oxide fuel cell short stack performance testing - Part A: Experimental analysis and μ-combined heat and power unit comparison

    Science.gov (United States)

    Mastropasqua, L.; Campanari, S.; Brouwer, J.

    2017-12-01

    The need to experimentally understand the detailed performance of SOFC stacks under operating conditions typical of commercial SOFC systems has prompted this two-part study. The steady state performance of a 6-cell short stack of yttria (Y2O3) stabilised zirconia (YSZ) with Ni/YSZ anodes and composite Sr-doped lanthanum manganite (LaMnO3, LSM)/YSZ cathodes is experimentally evaluated. In Part A, the stack characterisation is carried out by means of sensitivity analyses on the fuel utilisation factor and the steam-to-carbon ratio. Electrical and environmental performances are assessed and the results are compared with a commercial full-scale micro-CHP system, which comprises the same cells. The results show that the measured temperature dynamics of the short stack in a test stand environment are on the order of many minutes; therefore, one cannot neglect temperature dynamics for a precise measurement of the steady state polarisation behaviour. The overall polarisation performance is comparable to that of the full stack employed in the micro-CHP system, confirming the good representation that short-stack analyses can give of the entire SOFC module. The environmental performance is measured verifying the negligible values of NO emissions (<10 ppb) across the whole polarisation curve.

  9. Fuel processor for fuel cell power system

    Science.gov (United States)

    Vanderborgh, Nicholas E.; Springer, Thomas E.; Huff, James R.

    1987-01-01

    A catalytic organic fuel processing apparatus, which can be used in a fuel cell power system, contains within a housing a catalyst chamber, a variable speed fan, and a combustion chamber. Vaporized organic fuel is circulated by the fan past the combustion chamber with which it is in indirect heat exchange relationship. The heated vaporized organic fuel enters a catalyst bed where it is converted into a desired product such as hydrogen needed to power the fuel cell. During periods of high demand, air is injected upstream of the combustion chamber and organic fuel injection means to burn with some of the organic fuel on the outside of the combustion chamber, and thus be in direct heat exchange relation with the organic fuel going into the catalyst bed.

  10. Optimization of Fuel Cell System Operating Conditions for Fuel Cell Vehicles

    OpenAIRE

    Zhao, Hengbing; Burke, Andy

    2008-01-01

    Proton Exchange Membrane fuel cell (PEMFC) technology for use in fuel cell vehicles and other applications has been intensively developed in recent decades. Besides the fuel cell stack, air and fuel control and thermal and water management are major challenges in the development of the fuel cell for vehicle applications. The air supply system can have a major impact on overall system efficiency. In this paper a fuel cell system model for optimizing system operating conditions was developed wh...

  11. PEM - fuel cell system for residential applications

    Energy Technology Data Exchange (ETDEWEB)

    Britz, P. [Viessmann Werke GmbH and Co KG, 35107 Allendorf (Germany); Zartenar, N.

    2004-12-01

    Viessmann is developing a PEM fuel cell system for residential applications. The uncharged PEM fuel cell system has a 2 kW electrical and 3 kW thermal power output. The Viessmann Fuel Processor is characterized by a steam-reformer/burner combination in which the burner supplies the required heat to the steam reformer unit and the burner exhaust gas is used to heat water. Natural gas is used as fuel, which is fed into the reforming reactor after passing an integrated desulphurisation unit. The low temperature (600 C) fuel processor is designed on the basis of steam reforming technology. For carbon monoxide removal, a single shift reactor and selective methanisation is used with noble metal catalysts on monoliths. In the shift reactor, carbon monoxide is converted into hydrogen by the water gas shift reaction. The low level of carbon monoxide at the outlet of the shift reactor is further reduced, to approximately 20 ppm, downstream in the methanisation reactor, to meet PEM fuel cell requirements. Since both catalysts work at the same temperature (240 C), there is no requirement for an additional heat exchanger in the fuel processor. Start up time is less than 30 min. In addition, Viessmann has developed a 2 kW class PEFC stack, without humidification. Reformate and dry air are fed straight to the stack. Due to the dry operation, water produced by the cell reaction rapidly diffuses through the electrolyte membrane. This was achieved by optimising the MEA, the gas flow pattern and the operating conditions. The cathode is operated by an air blower. (Abstract Copyright [2004], Wiley Periodicals, Inc.)

  12. A Total Cost of Ownership Model for Low Temperature PEM Fuel Cells in Combined Heat and Power and Backup Power Applications

    Energy Technology Data Exchange (ETDEWEB)

    University of California, Berkeley; Wei, Max; Lipman, Timothy; Mayyas, Ahmad; Chien, Joshua; Chan, Shuk Han; Gosselin, David; Breunig, Hanna; Stadler, Michael; McKone, Thomas; Beattie, Paul; Chong, Patricia; Colella, Whitney; James, Brian

    2014-06-23

    A total cost of ownership model is described for low temperature proton exchange membrane stationary fuel cell systems for combined heat and power (CHP) applications from 1-250kW and backup power applications from 1-50kW. System designs and functional specifications for these two applications were developed across the range of system power levels. Bottom-up cost estimates were made for balance of plant costs, and detailed direct cost estimates for key fuel cell stack components were derived using design-for-manufacturing-and-assembly techniques. The development of high throughput, automated processes achieving high yield are projected to reduce the cost for fuel cell stacks to the $300/kW level at an annual production volume of 100 MW. Several promising combinations of building types and geographical location in the U.S. were identified for installation of fuel cell CHP systems based on the LBNL modelling tool DER CAM. Life-cycle modelling and externality assessment were done for hotels and hospitals. Reduced electricity demand charges, heating credits and carbon credits can reduce the effective cost of electricity ($/kWhe) by 26-44percent in locations such as Minneapolis, where high carbon intensity electricity from the grid is displaces by a fuel cell system operating on reformate fuel. This project extends the scope of existing cost studies to include externalities and ancillary financial benefits and thus provides a more comprehensive picture of fuel cell system benefits, consistent with a policy and incentive environment that increasingly values these ancillary benefits. The project provides a critical, new modelling capacity and should aid a broad range of policy makers in assessing the integrated costs and benefits of fuel cell systems versus other distributed generation technologies.

  13. Gravisensing in single-celled systems

    Science.gov (United States)

    Braun, M.; Limbach, C.

    Single-celled systems are favourable cell types for studying several aspects of gravisensing and gravitropic responses. Whether and how actin is involved in both processes in higher plant statocytes is still a matter of intensive debate. In single-celled and tip-growing characean rhizoids and protonemata, however, there is clear evidence that actin is a central keyplayer controlling polarized growth and the mechanisms of gravity sensing and growth reorientation. Both cell types exhibit a unique actin polymerization in the extending tip, strictly colocalized with the prominent ER-aggregate in the center of the Spitzenkoerper. The local accumulation of ADF and profilin in this central array suggest that actin polymerization is controlled by these actin-binding proteins, which can be regulated by calcium, pH and a variety of other parameters. Distinct actin filaments extend even into the outermost tip and form a dense meshwork in the apical and subapical region, before they become bundled by villin to form two populations of thick actin cables that generate rotational cytoplasmic streaming in the basal region. Actomyosin not only mediates the delivery of secretory vesicles to the growing tip and controls the incorporation pattern of cell wall material, but also coordinates the tip-focused distribution pattern of calcium channels in the apical membrane. They establish the tip-high calcium gradient, a prerequisite for exocytosis. Microgravity experiments have added much to our understanding that both cell types use an efficient actomyosin-based system to control and correct the position of their statoliths and to direct sedimenting statoliths to confined graviperception sites at the plasma membrane. Actin's involvement in the graviresponses is more indirect. The upward growth of negatively gravitropic protonemata was shown to be preceded by a statolith-induced relocalization the Ca2+-calcium gradient to the upper flank that does not occur in positively gravitropic

  14. Market optimization of a cluster of DG-RES, micro-CHP, heat pumps and energy storage within network constraints: The Power Matching City field test

    Energy Technology Data Exchange (ETDEWEB)

    Bliek, F.W.; Van den Noort, A. [KEMA, Arnhem (Netherlands); Roossien, B.; Kamphuis, I.G. [ECN Efficiency and Infrastructure, Petten (Netherlands); De Wit, J.; Van de Velde, J. [HumiQ, Barendrecht (Netherlands); Eijgelaar, M. [Essent, Arnhem (Netherlands)

    2010-10-15

    The share of renewable energy resources for electricity production, in a distributed setting (DG-RES), increases. The amount of energy transported via the electricity grid by substitution of fossil fuels for mobility applications (electric vehicles) and domestic heating (heat pumps) increases as well. Apart from the volume of electricity also the simultaneity factor increases at all grid levels. This poses unprecedented challenges to capacity management of the electricity infrastructure. A solution for tackling this challenge is using more active distribution networks, intelligent coordination of supply and demand using ICT and using the gas distribution network to mitigate electricity distribution bottlenecks. In the EU FP6 Energy Program Integral project, a large scale heterogeneous field test has been designed for application of the software agent based PowerMatcher technology. The test is conducted in a suburb of Groningen, Hoogkerk, and entails approximately 30 homes with either a 'dual fuel' heating system (electrical heat pump with gas-fired peak-burners) or a micro-CHP. Homes also may have PV. Furthermore, a wind production facility and nodes with electricity chargers for EVs and electricity storage are part of the Virtual Power Plant cluster, constructed in this way. Domestic heating systems have intrinsic operational flexibility in comfort management through the thermal mass of the dwellings. Furthermore, the field test comfort systems are equipped with possibilities for hot water storage for central heating as well as for tap-water. Finally, having additional gas-fired heating capacity for electrical heat pumps adds to increasing flexibility by switching the energy source dependent on the status of the electricity grid. Purpose of the field test is using this flexibility to react to phenomena in the electricity system. From a commercial perspective, the aggregated cluster reacts on small-time scale events like real-time portfolio imbalance

  15. Dynamic cell culture system (7-IML-1)

    Science.gov (United States)

    Cogoli, Augusto

    1992-01-01

    This experiment is one of the Biorack experiments being flown on the International Microgravity Laboratory 1 (MIL-1) mission as part of an investigation studying cell proliferation and performance in space. One of the objectives of this investigation is to assess the potential benefits of bioprocessing in space with the ultimate goal of developing a bioreactor for continuous cell cultures in space. This experiment will test the operation of an automated culture chamber that was designed for use in a Bioreactor in space. The device to be tested is called the Dynamic Cell Culture System (DCCS). It is a simple device in which media are renewed or chemicals are injected automatically, by means of osmotic pumps. This experiment uses four Type I/O experiment containers. One DCCS unit, which contains a culture chamber with renewal of medium and a second chamber without a medium supply fits in each container. Two DCCS units are maintained under zero gravity conditions during the on-orbit period. The other two units are maintained under 1 gh conditions in a 1 g centrifuge. The schedule for incubator transfer is given.

  16. Exploratory studies on some electrochemical cell systems

    Science.gov (United States)

    Chaudhuri, Srikumar; Guha, D.

    Exploratory studies were conducted on cell systems with different metal anodes, and iodine and sulphur mixed with graphite powder in a polymer matrix as cathodes, using different electrolytes in non-aqueous and aqueous media as ionic charge carriers. The electrical conductance of the electrolyte solutions in aqueous and non-aqueous solvents, the open circuit voltage (OCV) and short circuit current (SCC) for the different cell systems were measured. To date, the non-aqueous solvents used in our studies were dimethylformamide, formamide, dioxan, and nitrobenzene, and the electrolytes used were potassium iodide, caustic potash, cetyltrimethylammonium bromide (CTAB), sodium lauryl sulphate (SLS) and calcium chloride. These electrolytes were used in both non-aqueous and aqueous media. In general, aqueous electrolyte solutions gave a better performance than non-aqueous electrolyte solutions. Of the aqueous electrolytes, the highest conductance was shown by potassium chloride solution in water (conductance=0.0334 mho). However, the best OCV and SCC were shown by aluminium as anode and iodine as cathode with a saturated solution of caustic potash in water. The OCV was 1.85 V and the SCC was 290 mA cm -2. The highest conductance among the non-aqueous systems was shown by caustic potash in formamide. (Conductance=0.013 mho.) The best OCV and SCC, however, were shown by a zinc anode and iodine cathode with saturated potassium chloride in formamide, having an OCV of 1.55 V and an SCC of 150 mA cm -2. Further studies are in progress to obtain detailed performance data and recharging characteristics of some of the more promising systems reported here.

  17. Systems Biology for Organotypic Cell Cultures

    Energy Technology Data Exchange (ETDEWEB)

    Grego, Sonia [RTI International, Research Triangle Park, NC (United States); Dougherty, Edward R. [Texas A & M Univ., College Station, TX (United States); Alexander, Francis J. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Auerbach, Scott S. [National Inst. of Environmental Health Sciences, Research Triangle Park, NC (United States); Berridge, Brian R. [GlaxoSmithKline, Research Triangle Park, NC (United States); Bittner, Michael L. [Translational Genomics Research Inst., Phoenix, AZ (United States); Casey, Warren [National Inst. of Environmental Health Sciences, Research Triangle Park, NC (United States); Cooley, Philip C. [RTI International, Research Triangle Park, NC (United States); Dash, Ajit [HemoShear Therapeutics, Charlottesville, VA (United States); Ferguson, Stephen S. [National Inst. of Environmental Health Sciences, Research Triangle Park, NC (United States); Fennell, Timothy R. [RTI International, Research Triangle Park, NC (United States); Hawkins, Brian T. [RTI International, Research Triangle Park, NC (United States); Hickey, Anthony J. [RTI International, Research Triangle Park, NC (United States); Kleensang, Andre [Johns Hopkins Univ., Baltimore, MD (United States). Center for Alternatives to Animal Testing; Liebman, Michael N. [IPQ Analytics, Kennett Square, PA (United States); Martin, Florian [Phillip Morris International, Neuchatel (Switzerland); Maull, Elizabeth A. [National Inst. of Environmental Health Sciences, Research Triangle Park, NC (United States); Paragas, Jason [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Qiao, Guilin [Defense Threat Reduction Agency, Ft. Belvoir, VA (United States); Ramaiahgari, Sreenivasa [National Inst. of Environmental Health Sciences, Research Triangle Park, NC (United States); Sumner, Susan J. [RTI International, Research Triangle Park, NC (United States); Yoon, Miyoung [The Hamner Inst. for Health Sciences, Research Triangle Park, NC (United States); ScitoVation, Research Triangle Park, NC (United States)

    2016-08-04

    Translating in vitro biological data into actionable information related to human health holds the potential to improve disease treatment and risk assessment of chemical exposures. While genomics has identified regulatory pathways at the cellular level, translation to the organism level requires a multiscale approach accounting for intra-cellular regulation, inter-cellular interaction, and tissue/organ-level effects. Tissue-level effects can now be probed in vitro thanks to recently developed systems of three-dimensional (3D), multicellular, “organotypic” cell cultures, which mimic functional responses of living tissue. However, there remains a knowledge gap regarding interactions across different biological scales, complicating accurate prediction of health outcomes from molecular/genomic data and tissue responses. Systems biology aims at mathematical modeling of complex, non-linear biological systems. We propose to apply a systems biology approach to achieve a computational representation of tissue-level physiological responses by integrating empirical data derived from organotypic culture systems with computational models of intracellular pathways to better predict human responses. Successful implementation of this integrated approach will provide a powerful tool for faster, more accurate and cost-effective screening of potential toxicants and therapeutics. On September 11, 2015, an interdisciplinary group of scientists, engineers, and clinicians gathered for a workshop in Research Triangle Park, North Carolina, to discuss this ambitious goal. Participants represented laboratory-based and computational modeling approaches to pharmacology and toxicology, as well as the pharmaceutical industry, government, non-profits, and academia. Discussions focused on identifying critical system perturbations to model, the computational tools required, and the experimental approaches best suited to generating key data. This consensus report summarizes the discussions held.

  18. Glial Cells: The Other Cells of the Nervous System

    Indian Academy of Sciences (India)

    In the early part of the twentieth century, the important role played by a set of small cells under pathological conditions in the brain was recognized for the first time by De RioHortega. He developed a staining technique that could distinguish these cells from neurons and other glial cells and coined the term. 'microglia' to ...

  19. Glial Cells: The Other Cells of the Nervous System

    Indian Academy of Sciences (India)

    specializes in electron microscopy of muscle, nerve and brain tumors. Part 1. An Introduction to Glial. Cells, Resonance, VoL7, No.1, pp.4-lO, 2002. Keywords. Glial cells, astrocytes, reactive gliosis, radial glia. In 1846 Rudolf Virchow recognized for the first time that the vertebrate brain had a large population of cells other.

  20. Glial Cells: The Other Cells of the Nervous System

    Indian Academy of Sciences (India)

    General Properties of Glial Cells. Glial cells are observed to be metabolically active, very like any other cell of the body, with the usual array of organelles. Depos- its of fats and glycogen are often seen in their cytoplasm. Micro- scopically they can be distinguished from the neurons on the basis of the absence of an axon.

  1. The Design, Construction, and Experimental Evaluation of a Compact Thermoacoustic-Stirling Engine Generator for Use in a micro-CHP Appliance

    Science.gov (United States)

    Wilcox, Douglas A., Jr.

    Micro combined heat and power or micro-CHP is the simultaneous generation of useful heat and electricity on a residential scale. The heat and electricity are produced at the point of use, avoiding the distribution losses associated with a centralized power plant. These appliances combine a conventional gas-fired condensing boiler with an electric power module capable of generating electricity from the heat of combustion. Currently, the leading power modules for micro-CHP appliances are free-piston Stirling engines (FPSEs) which can generate 1050 watts of electricity at a thermal-to-electric efficiency of 26%.[1] These external combustion engines have been under development for the last 25 years, with FPSE micro-CHP appliances only recently being introduced to the commercial market. Publications by developers assert unlimited service life and high efficiency, with low noise and emissions; but despite these claims, the actual reliability and cost of manufacturing has prevented their successful mass-market adoption. A Thermoacoustic-Stirling Engine Generator or TaSEG is one possible alternative to FPSE's. A TaSEG uses a thermoacoustic engine, or acoustic heat engine, which can efficiently convert high temperature heat into acoustic power while maintaining a simple design with fewer moving parts than traditional FPSE's. This simpler engine is coupled to an electrodynamic alternator capable of converting acoustic power into electricity. This thesis outlines the design, construction, and experimental evaluation of a TaSEG which is appropriate for integration with a gas burner inside of a residential micro- CHP appliance. The design methodology is discussed, focusing on how changes in the geometry affected the predicted performance. Details of its construction are given and the performance of the TaSEG is then outlined. The TaSEG can deliver 132 watts of electrical output power to an electric load with an overall measured thermal-to-electric (first law) efficiency of eta

  2. A feasible system integrating combined heating and power system with ground-source heat pump

    International Nuclear Information System (INIS)

    Li, HongQiang; Kang, ShuShuo; Yu, Zhun; Cai, Bo; Zhang, GuoQiang

    2014-01-01

    A system integrating CHP (combined heating and power) subsystem based on natural gas and GSHP (ground-source heat pump subsystem) in series is proposed. By help of simulation software-Aspen Plus, the energy performance of a typical CHP and GSHP-S (S refers to ‘in series’) system was analyzed. The results show that the system can make a better use of waste heat in flue gas from CHP (combined heating and power subsystem). The total system energy efficiency is 123% and the COP (coefficient of performance) of GSHP (ground-source heat pump) subsystem is 5.3. A referenced CHP and GSHP-P (P refers to ‘in parallel’) system is used for comparison; its total system energy efficiency and COP of GSHP subsystem are 118.6% and 3.5 respectively. Compared with CHP and GSHP-P system with different operating parameters, the CHP and GSHP-S system can increase total system energy efficiency by 0.8–34.7%, with related output ratio of heat to power (R) from 1.9 to 18.3. Furthermore, the COP of GSHP subsystem can be increased between the range 3.6 and 6, which is much higher than that in conventional CHP and GSHP-P system. This study will be helpful for other efficient GSHP systems integrating if there is waste heat or other heat resources with low temperature. - Highlights: • CHP system based on natural gas and ground source heat pump. • The new system can make a better utilization of waste heat in flue gas by a special way. • The proposed system can realize energy saving potential from 0.8 to 34.7%. • The coefficient of performance of ground source heat pump subsystem is significantly improved from 3.5 to 3.6–6. • Warm water temperature and percentage of flue gas used to reheat are key parameters

  3. Compact Fuel-Cell System Would Consume Neat Methanol

    Science.gov (United States)

    Narayanan, Sekharipuram; Kindler, Andrew; Valdez, Thomas

    2007-01-01

    In a proposed direct methanol fuel-cell electric-power-generating system, the fuel cells would consume neat methanol, in contradistinction to the dilute aqueous methanol solutions consumed in prior direct methanol fuel-cell systems. The design concept of the proposed fuel-cell system takes advantage of (1) electro-osmotic drag and diffusion processes to manage the flows of hydrogen and water between the anode and the cathode and (2) evaporative cooling for regulating temperature. The design concept provides for supplying enough water to the anodes to enable the use of neat methanol while ensuring conservation of water for the whole fuel-cell system.

  4. Generation of a patterned co-culture system composed of adherent cells and immobilized nonadherent cells.

    Science.gov (United States)

    Yamazoe, Hironori; Ichikawa, Takashi; Hagihara, Yoshihisa; Iwasaki, Yasuhiko

    2016-02-01

    Patterned co-culture is a promising technique used for fundamental investigation of cell-cell communication and tissue engineering approaches. However, conventional methods are inapplicable to nonadherent cells. In this study, we aimed to establish a patterned co-culture system composed of adherent and nonadherent cells. Nonadherent cells were immobilized on a substrate using a cell membrane anchoring reagent conjugated to a protein, in order to incorporate them into the co-culture system. Cross-linked albumin film, which has unique surface properties capable of regulating protein adsorption, was used to control their spatial localization. The utility of our approach was demonstrated through the fabrication of a patterned co-culture consisting of micropatterned neuroblastoma cells surrounded by immobilized myeloid cells. Furthermore, we also created a co-culture system composed of cancer cells and immobilized monocytes. We observed that monocytes enhanced the drug sensitivity of cancer cells and its influence was limited to cancer cells located near the monocytes. Therefore, the incorporation of nonadherent cells into a patterned co-culture system is useful for creating culture systems containing immune cells, as well as investigating the influence of these immune cells on cancer drug sensitivity. Various methods have been proposed for creating patterned co-culture systems, in which multiple cell types are attached to a substrate with a desired pattern. However, conventional methods, including our previous report published in Acta Biomaterialia (2010, 6, 526-533), are unsuitable for nonadherent cells. Here, we developed a novel method that incorporates nonadherent cells into the co-culture system, which allows us to precisely manipulate and study microenvironments containing nonadherent and adherent cells. Using this technique, we demonstrated that monocytes (nonadherent cells) could enhance the drug sensitivity of cancer cells and that their influence had a

  5. Photovoltaic power generation system with photovoltaic cells as bypass diodes

    Science.gov (United States)

    Lentine, Anthony L.; Nielson, Gregory N.; Tauke-Pedretti, Anna; Cruz-Campa, Jose Luis; Okandan, Murat

    2017-11-28

    A photovoltaic power generation system that includes a solar panel is described herein. The solar panel includes a photovoltaic sub-module, which includes a group of microsystem enabled photovoltaic cells. The group includes a first string of photovoltaic cells, a second string of photovoltaic cells, and a differing photovoltaic cell. Photovoltaic cells in the first string are electrically connected in series, and photovoltaic cells in the second string are electrically connected in series. Further, the first string of photovoltaic cells, the second string of photovoltaic cells, and the differing photovoltaic cell are electrically connected in parallel. Moreover, the differing photovoltaic cell is used as a bypass diode for the first string of photovoltaic cells and the second string of photovoltaic cells.

  6. Glial Cells: The Other Cells of the Nervous System

    Indian Academy of Sciences (India)

    result of defective Schwann cells and not the axons. A mutant mouse called Trembler has an inherited disorder which leads to gross abnormality in myelin formation. .... depletion of vesicles carrying the neurotransmitters in the presynaptic neurons. Recently, Schwann cells have been implicated in the synaptic depression.

  7. Fuel cells for stationary energy supply; Brennstoffzellen in der stationaeren Energieversorgung

    Energy Technology Data Exchange (ETDEWEB)

    Leprich, Uwe; Thiele, Andreas [Institut fuer ZukunftsEnergieSysteme (IZES), Saarbruecken (Germany)

    2005-06-15

    Starting point for this investigation was the question, whether the incentives, caused by the CHP law from March the 19th 2002, are short- and medium term adequate to introduce fuel cells as small CHP plants broadly on the market or rather develop them at least to a standard of market maturity. This has - based on our analysis - definitely to be answered in the negative: for this, the fixed bonus is too small to influence the costs for investment and running of a fuel cell plant lasting. One of the aims of the CHP law - the reduction of the yearly CO2-emissions in Germany by a broader introduction of the technology on the market - can actually not be reached. Although, fuel cells may obtain a quite important climate-political significance, if their economical availability will be secured and related basic conditions are set today. By the CHP law, the federal government however demonstrated publicly that it is willing to support the development of the fuel cell and its introduction on the market. This signal is not only supporting the industry to align its middle- and long term decisions but it is also helping users and operators of fuel cells by providing a legal security about the guarantee for grid connection and remuneration Based on the perspectives for an establishing of small CHP plants including fuel cells, the range of possible stimulating and supporting measures was investigated in a second step. While doing so, it was differentiated between a flanking of the existing CHP law, its further development and other alternative measures. By this, there are several starting points to realize changes or rather adaptations in the CHP law. According to this investigation and in the interest of an increased spreading of small CHP- and fuel cell plants, these possibilities should be made use of as fast as possible. The investigation was terminated by examinating selected technical, energy-economical as well as energy political chances and requirements for hydrogen

  8. Decision Support Tools for Electricity Retailers, Wind Power and CHP Plants Using Probabilistic Forecasts

    DEFF Research Database (Denmark)

    Zugno, Marco; Morales González, Juan Miguel; Madsen, Henrik

    2015-01-01

    This paper reviews a number of applications of optimization under uncertainty in energy markets resulting from the research project ENSYMORA. A general mathematical formulation applicable to problems of optimization under uncertainty in energy markets is presented. This formulation can......: trading for a price-maker wind power producer, management of heat and power systems, operation for retailers in a dynamic-price market. A selection of results shows the viability and appropriateness of the presented stochastic optimization approaches for managing energy systems under uncertainty....

  9. Distributed MPC Applied to a Network of Households With Micro-CHP and Heat Storage

    NARCIS (Netherlands)

    Larsen, G.K. H.; van Foreest, N.D.; Scherpen, J.M.A.

    This paper considers heat and power production from micro Combined Heat and Power systems and heat storage in a network of households. The goal is to balance the local heat demand and supply in combination with balancing the power supply and demand in the network. The on-off decisions of the local

  10. Cell fate control in the developing central nervous system

    Energy Technology Data Exchange (ETDEWEB)

    Guérout, Nicolas; Li, Xiaofei; Barnabé-Heider, Fanie, E-mail: Fanie.Barnabe-Heider@ki.se

    2014-02-01

    The principal neural cell types forming the mature central nervous system (CNS) are now understood to be diverse. This cellular subtype diversity originates to a large extent from the specification of the earlier proliferating progenitor populations during development. Here, we review the processes governing the differentiation of a common neuroepithelial cell progenitor pool into mature neurons, astrocytes, oligodendrocytes, ependymal cells and adult stem cells. We focus on studies performed in mice and involving two distinct CNS structures: the spinal cord and the cerebral cortex. Understanding the origin, specification and developmental regulators of neural cells will ultimately impact comprehension and treatments of neurological disorders and diseases. - Highlights: • Similar mechanisms regulate cell fate in different CNS cell types and structures. • Cell fate regulators operate in a spatial–temporal manner. • Different neural cell types rely on the generation of a diversity of progenitor cells. • Cell fate decision is dictated by the integration of intrinsic and extrinsic signals.

  11. Cell fate control in the developing central nervous system

    International Nuclear Information System (INIS)

    Guérout, Nicolas; Li, Xiaofei; Barnabé-Heider, Fanie

    2014-01-01

    The principal neural cell types forming the mature central nervous system (CNS) are now understood to be diverse. This cellular subtype diversity originates to a large extent from the specification of the earlier proliferating progenitor populations during development. Here, we review the processes governing the differentiation of a common neuroepithelial cell progenitor pool into mature neurons, astrocytes, oligodendrocytes, ependymal cells and adult stem cells. We focus on studies performed in mice and involving two distinct CNS structures: the spinal cord and the cerebral cortex. Understanding the origin, specification and developmental regulators of neural cells will ultimately impact comprehension and treatments of neurological disorders and diseases. - Highlights: • Similar mechanisms regulate cell fate in different CNS cell types and structures. • Cell fate regulators operate in a spatial–temporal manner. • Different neural cell types rely on the generation of a diversity of progenitor cells. • Cell fate decision is dictated by the integration of intrinsic and extrinsic signals

  12. Decision Support Tools for Electricity Retailers, Wind Power and CHP Plants Using Probabilistic Forecasts

    Directory of Open Access Journals (Sweden)

    Marco Zugno

    2015-06-01

    Full Text Available This paper reviews a number of applications of optimization under uncertainty in energy markets resulting from the research project ENSYMORA. A general mathematical formulation applicable to problems of optimization under uncertainty in energy markets is presented. This formulation can be effortlessly adapted to describe different approaches: the deterministic one (usable within a rolling horizon scheme, stochastic programming and robust optimization. The different features of this mathematical formulation are duly interpreted with a view to the energy applications reviewed in this paper: trading for a price-maker wind power producer, management of heat and power systems, operation for retailers in a dynamic-price market. A selection of results shows the viability and appropriateness of the presented stochastic optimization approaches for managing energy systems under uncertainty.

  13. Advanced Fuel Cell System Thermal Management for NASA Exploration Missions

    Science.gov (United States)

    Burke, Kenneth A.

    2009-01-01

    The NASA Glenn Research Center is developing advanced passive thermal management technology to reduce the mass and improve the reliability of space fuel cell systems for the NASA exploration program. An analysis of a state-of-the-art fuel cell cooling systems was done to benchmark the portion of a fuel cell system s mass that is dedicated to thermal management. Additional analysis was done to determine the key performance targets of the advanced passive thermal management technology that would substantially reduce fuel cell system mass.

  14. Multi-stage fuel cell system method and apparatus

    Science.gov (United States)

    George, Thomas J.; Smith, William C.

    2000-01-01

    A high efficiency, multi-stage fuel cell system method and apparatus is provided. The fuel cell system is comprised of multiple fuel cell stages, whereby the temperatures of the fuel and oxidant gas streams and the percentage of fuel consumed in each stage are controlled to optimize fuel cell system efficiency. The stages are connected in a serial, flow-through arrangement such that the oxidant gas and fuel gas flowing through an upstream stage is conducted directly into the next adjacent downstream stage. The fuel cell stages are further arranged such that unspent fuel and oxidant laden gases too hot to continue within an upstream stage because of material constraints are conducted into a subsequent downstream stage which comprises a similar cell configuration, however, which is constructed from materials having a higher heat tolerance and designed to meet higher thermal demands. In addition, fuel is underutilized in each stage, resulting in a higher overall fuel cell system efficiency.

  15. CHP: Combined Heat and Power: a vision of energy efficiency; Cogeracao: uma visao de eficiencia energetica

    Energy Technology Data Exchange (ETDEWEB)

    Andrade, Osvaldo A.S.N. de; Abreu, Melissa E. de; Marcal, Roberto L.; Ferreira, Ademilson D.; Ferreira, Patricia E.; Monterio, Glauber J.R.; Silva, Ademir B. [PETROBRAS, Rio de Janeiro, RJ (Brazil)

    2008-07-01

    The installation of a cogeneration plant has been the subject of discussions on alternatives in the Brazilian energy matrix. Considered viable solution in the not too distant past, 2001, when Brazil was undergoing a process of the economic slowdown, lack of investments in the energy sector, unemployment and reaching the peak of the crisis with the rationing of electricity. The principle of the cogeneration system is designed primarily to meet electrical demand, so there is no surplus production of energy and do not need to buy with the concessionaire, except in cases of the system stops on account of maintenance. However, there is a recovery of waste heat produced in thermodynamic processes for generation of electricity within a model that 'conventional' would be wasted. In this case, the exploitation can be given in the form of steam, hot water and/or cold, for secondary application, or can not be linked to a process. Based on the results of the fieldwork, aims to show that, despite the limitations inherent in the process of cogeneration, is justified economically the installation of this system in relation to the growth of procedures developed in CENPES and its resident effective. (author)

  16. Economics of Direct Hydrogen Polymer Electrolyte Membrane Fuel Cell Systems

    Energy Technology Data Exchange (ETDEWEB)

    Mahadevan, Kathyayani

    2011-10-04

    Battelle's Economic Analysis of PEM Fuel Cell Systems project was initiated in 2003 to evaluate the technology and markets that are near-term and potentially could support the transition to fuel cells in automotive markets. The objective of Battelle?s project was to assist the DOE in developing fuel cell systems for pre-automotive applications by analyzing the technical, economic, and market drivers of direct hydrogen PEM fuel cell adoption. The project was executed over a 6-year period (2003 to 2010) and a variety of analyses were completed in that period. The analyses presented in the final report include: Commercialization scenarios for stationary generation through 2015 (2004); Stakeholder feedback on technology status and performance status of fuel cell systems (2004); Development of manufacturing costs of stationary PEM fuel cell systems for backup power markets (2004); Identification of near-term and mid-term markets for PEM fuel cells (2006); Development of the value proposition and market opportunity of PEM fuel cells in near-term markets by assessing the lifecycle cost of PEM fuel cells as compared to conventional alternatives used in the marketplace and modeling market penetration (2006); Development of the value proposition of PEM fuel cells in government markets (2007); Development of the value proposition and opportunity for large fuel cell system application at data centers and wastewater treatment plants (2008); Update of the manufacturing costs of PEM fuel cells for backup power applications (2009).

  17. The activation of the adaptive immune system: cross-talk between antigen-presenting cells, T cells and B cells.

    Science.gov (United States)

    den Haan, Joke M M; Arens, Ramon; van Zelm, Menno C

    2014-12-01

    The adaptive immune system consists of T and B cells that express clonally distributed antigen receptors. To achieve functional adaptive immune responses, antigen-specific T cell populations are stimulated by professional antigen-presenting cells like dendritic cells (DCs), which provide crucial stimulatory signals for efficient expansion and development of effector functions. Antigen-specific B cells receive costimulatory signals from helper T cells to stimulate affinity maturation and isotype switching. Here we elaborate on the interactions between DCs, T cells and B cells, and on the important signals for efficient induction of adaptive immune responses. Copyright © 2014 Elsevier B.V. All rights reserved.

  18. High Temperature PEM Fuel Cell Systems, Control and Diagnostics

    DEFF Research Database (Denmark)

    Andreasen, Søren Juhl; Kær, Søren Knudsen; Justesen, Kristian Kjær

    2015-01-01

    Various system topologies are available when it comes to designing high temperature PEM fuel cell systems. Very simple system designs are possible using pure hydrogen, and more complex system designs present themselves when alternative fuels are desired, using reformer systems. The use of reforme...

  19. Thermal Heat and Power Production with Models for Local and Regional Energy Systems

    Energy Technology Data Exchange (ETDEWEB)

    Saether, Sturla

    1999-07-01

    The primary goal of this thesis is the description and modelling of combined heat and power systems as well as analyses of thermal dominated systems related to benefits of power exchange. Large power plants with high power efficiency (natural gas systems) and heat production in local heat pumps can be favourable in areas with low infrastructure of district heating systems. This system is comparable with typical combined heat and power (CHP) systems based on natural gas with respect to efficient use of fuel energy. The power efficiency obtainable from biomass and municipal waste is relatively low and the advantage of CHP for this system is high compared to pure power production with local heat pumps for heat generation. The advantage of converting pure power systems into CHP systems is best for power systems with low power efficiency and heat production at low temperature. CHP systems are divided into two main groups according to the coupling of heat and power production. Some CHP systems, especially those with strong coupling between heat and power production, may profit from having a thermal heat storage subsystem. District heating temperatures direct the heat to power ratio of the CHP units. The use of absorption chillers driven by district heating systems are also evaluated with respect to enhancing the utilisation of district heating in periods of low heat demand. Power exchange between a thermal dominated and hydropower system is found beneficial. Use of hydropower as a substitute for peak power production in thermal dominated systems is advantageous. Return of base load from the thermal dominated system to the hydropower system can balance in the net power exchange.

  20. Structure and function of stem cell pools in mammalian cell renewal systems

    International Nuclear Information System (INIS)

    Fliedner, T.M.; Nothdurft, W.

    1979-01-01

    Stem cells play a key-role in the maintenance of the equilibrium between cell loss and cell production in cell renewal systems as well as in the understanding of the radiation pathophysiology of mammalian organisms. The integrity of mammalian organisms with the need to maintain a constant ''millieu interior'' is depending on the normal functioning of cell renewal systems, especially those of epithelial surfaces and blood cell forming organs. All cell renewal systems of bodies have a very similar functional structure consisting of functional, proliferative - amplifying and stem cell compartments. They differ in transit and cell cycle times and in the number of amplification division - aside from the difference in their functional and biochemical make-up. The stem cell pools are providing the cells capable of differentiation without depleting their own kind. This can be achieved by symmetrical or assymmetrical stem cell division. In normal steady state, 50% of the stem cell division remain in the stem cell pool, while the other 50% leave it to differentiate, proliferate and mature, hemopoietic system is distributed throughout bodies. This is an important factor in the radiation biology of mammalian organisms since the loss of function in one area can be compensated for by more production in other areas, and locally depleted sites can be reseeded with the stem cells migrating in from blood. (Yamashita, S.)

  1. Cell Delivery System for Traumatic Brain Injury

    Science.gov (United States)

    2008-03-21

    Injury Using Novel Matrices and Human Bone Marrow Stem Cells.” 4th Annual Los Angeles Tissue Engineering Meeting, UCLA Dec. 2006. (c) Presentations...Task 1). Task 1: Differentiate Adult Stem Cells into Neurons. Each of three different adult stem cell types (ADSCs, MSCs and amniotic -derived...gel properties. Evaluate gel material properties such as liquid to gel transition temperature, fiber and pore sizes, mechanical strength, resistance

  2. A Geothermal Energy Supported Gas-steam Cogeneration Unit as a Possible Replacement for the Old Part of a Municipal CHP Plant (TEKO

    Directory of Open Access Journals (Sweden)

    L. Böszörményi

    2001-01-01

    Full Text Available The need for more intensive utilization of local renewable energy sources is indisputable. Under the current economic circumstances their competitiveness in comparison with fossil fuels is rather low, if we do not take into account environmental considerations. Integrating geothermal sources into combined heat and power production in a municipal CHP plant would be an excellent solution to this problem. This concept could lead to an innovative type of power plant - a gas-steam cycle based, geothermal energy supported cogeneration unit.

  3. Advances in Materials and System Technology for Portable Fuel Cells

    Science.gov (United States)

    Narayanan, Sekharipuram R.

    2007-01-01

    This viewgraph presentation describes the materials and systems engineering used for portable fuel cells. The contents include: 1) Portable Power; 2) Technology Solution; 3) Portable Hydrogen Systems; 4) Direct Methanol Fuel Cell; 5) Direct Methanol Fuel Cell System Concept; 6) Overview of DMFC R&D at JPL; 7) 300-Watt Portable Fuel Cell for Army Applications; 8) DMFC units from Smart Fuel Cell Inc, Germany; 9) DMFC Status and Prospects; 10) Challenges; 11) Rapid Screening of Well-Controlled Catalyst Compositions; 12) Screening of Ni-Zr-Pt-Ru alloys; 13) Issues with New Membranes; 14) Membranes With Reduced Methanol Crossover; 15) Stacks; 16) Hybrid DMFC System; 17) Small Compact Systems; 18) Durability; and 19) Stack and System Parameters for Various Applications.

  4. Bioengineered cell culture systems of central nervous system injury and disease

    OpenAIRE

    Teixeira, Fábio Gabriel Rodrigues; Vasconcelos, Natália L.; Gomes, Eduardo Domingos Correia; Marques, Fernanda; Sousa, João Carlos; Sousa, Nuno; Silva, Nuno A.; Silva, Rita Catarina Assunção Ribeiro; Lima, Rui Augusto Ribeiro; Salgado, A. J.

    2016-01-01

    Cell culture systems, either 2D or explant based, have been pivotal to better understand the pathophysiology of several central nervous system (CNS) disorders. Recently, bioengineered cell culture systems have been proposed as an alternative to the traditional setups. These innovative systems often combine different cell populations in 3D environments that more closely recapitulate the different niches that exist within the developing or adult CNS. Given the importance of such systems for the...

  5. System for adding sulfur to a fuel cell stack system for improved fuel cell stability

    Science.gov (United States)

    Mukerjee, Subhasish [Pittsford, NY; Haltiner, Jr., Karl J; Weissman, Jeffrey G [West Henrietta, NY

    2012-03-06

    A system for adding sulfur to a fuel cell stack, having a reformer adapted to reform a hydrocarbon fuel stream containing sulfur contaminants, thereby providing a reformate stream having sulfur; a sulfur trap fluidly coupled downstream of the reformer for removing sulfur from the reformate stream, thereby providing a desulfurized reformate stream; and a metering device in fluid communication with the reformate stream upstream of the sulfur trap and with the desulfurized reformate stream downstream of the sulfur trap. The metering device is adapted to bypass a portion of the reformate stream to mix with the desulfurized reformate stream, thereby producing a conditioned reformate stream having a predetermined sulfur concentration that gives an acceptable balance of minimal drop in initial power with the desired maximum stability of operation over prolonged periods for the fuel cell stack.

  6. Cells of the immune system in atherosclerosis – chosen data

    Directory of Open Access Journals (Sweden)

    Paulina Niedźwiedzka-Rystwej

    2010-08-01

    Full Text Available Development of artherosclerosis is associated with participation of various cell types of the immune system such as: granulocytes, B and T lymphocytes, mast cells, dendritic cells and progenitor cells. Cytokines and growth factors have a great impact on activation of the atheromatous plaque. This pathological process results in increase of artery’s tunic intima thickness, leading to coronary heart disease, myocardial infarction or stroke. It is suggested that a closer look at participation of the immune system cells in artherosclerosis may contribute to a change in the profile of therapy of this disease.

  7. Fuel cell/gas turbine system performance studies

    Energy Technology Data Exchange (ETDEWEB)

    Lee, G.T.; Sudhoff, F.A.

    1996-12-31

    Because of the synergistic effects (higher efficiencies, lower emissions) of combining a fuel cell and a gas turbine into a power generation system, many potential system configurations were studied. This work is focused on novel power plant systems by combining gas turbines, solid oxide fuel cells, and a high-temperature heat exchanger; these systems are ideal for the distributed power and on- site markets in the 1-5 MW size range.

  8. A methanol/air fuel cell system

    Science.gov (United States)

    Asher, W. J.

    1974-01-01

    High power-density, self-regulating fuel cell develops electrical power from catalyzed reaction between methanol and atmospheric oxygen. Cells such as these are of particular interest, because they may one day offer an emission-free, extremely efficient alternative to internal-combustion engines as power source.

  9. Biophysics of Hair Cell Sensory Systems

    NARCIS (Netherlands)

    Duifhuis, Hendrikus; Horst, Johannes; van Dijk, Pim; van Netten, Sietse

    1993-01-01

    The last decade revealed to auditory researchers that hair cells can not only detect and process mechanical energy, but are also able to produce it. Thanks to the active hair cell, ears can produce otoacoustic emissions. This book gives the newest insights into the biophysics and physiology of

  10. Coupling Immunodeficiency factors to a normal cell system growing conjointly with tumor cells

    Science.gov (United States)

    Shojania Feizabadi, Mitra; Witten, Tarynn M.

    2014-03-01

    In this work, we modify Witten's conjoint normal-tumor cell model in order to incorporate the presence of a simple immune system. We first examine the behavior of normal and tumor cells when tumor cells interact with surrounding normal cells. We then extend our model and add the effects of a simple immune system, immune-suppression factors and immune-chemotherapeutics agents. The evolution of the system variables is investigated via computer simulation. We show that the evolution of normal and tumor cells population is significantly affected by the choice of drug or immunodeficiency.

  11. Glial Cells: The Other Cells of the Nervous System

    Indian Academy of Sciences (India)

    Theodor Schwann, the German physiologist who first pro- pounded the cell theory with M Schleiden, had diverse interests. He was not only the first to isolate the enzyme pepsin, but also investigated muscle contraction and nerve structure. In the mid nineteenth century Schwann discovered that a sheath made up of myelin ...

  12. Glial Cells: The Other Cells of the Nervous System

    Indian Academy of Sciences (India)

    later, various types of glial cells were identified and de- ... walls of the blood vessel and are considered to be responsible for ... astrocytes - these are predominantly present in the gray matter and have fewer microfilaments in their cytoplasm. Two types of astrocytes (Type 1 and Type 2) have been reported in cultures of.

  13. Manufacturing of cells and stacks for SOFC development, test and demonstration projects and SOFC hotbox design development

    Energy Technology Data Exchange (ETDEWEB)

    2008-09-15

    The purpose of this project is to support the continued SOFC development through manufacturing process optimization and manufacturing of SOFC cells and stacks. These cells and stacks will serve as a necessary base for the development activities and for the establishment of a number of test and demonstration activities. The manufacture will also help provide operating experience and reduce manufacturing cost. Another main focus of the manufacturing is to assure technical improvements and reliability. It is imperative to the eventual success of the technology that test and demonstration is carried out in the pre-market conditions that will exist for the next years in the three market segments targeted by TOFC (Distributed generation, micro CHP and APU incl. marine APU). Finally, the project also includes development activities focusing on the stack-system interface (hotbox design development) and on dealing with transients and start up and shut down times, which is of particular importance for APU and micro CHP applications. Three topics are addressed:1) Cell manufacture, including production development, capacity lift and manuf. of cells for test and demonstration; 2) Stack manufacture and test, including a test facility, stack manuf. and test of stacks in a system at HCV; 3) Hotbox design development, including design, prototype construction and testing. The progress of this project is documented. Major achievements are successful manufacture of adequate amounts of cells and stacks according to the application. Furthermore significant over-performance in design, construction and test of a methanol based hotbox prototype as well as publication of this. (au)

  14. Single-cell technologies to study the immune system.

    Science.gov (United States)

    Proserpio, Valentina; Mahata, Bidesh

    2016-02-01

    The immune system is composed of a variety of cells that act in a coordinated fashion to protect the organism against a multitude of different pathogens. The great variability of existing pathogens corresponds to a similar high heterogeneity of the immune cells. The study of individual immune cells, the fundamental unit of immunity, has recently transformed from a qualitative microscopic imaging to a nearly complete quantitative transcriptomic analysis. This shift has been driven by the rapid development of multiple single-cell technologies. These new advances are expected to boost the detection of less frequent cell types and transient or intermediate cell states. They will highlight the individuality of each single cell and greatly expand the resolution of current available classifications and differentiation trajectories. In this review we discuss the recent advancement and application of single-cell technologies, their limitations and future applications to study the immune system. © 2015 The Authors. Immunology Published by John Wiley & Sons Ltd.

  15. Application of Fuel Cells to Marine Power Generation Systems

    OpenAIRE

    Senichi, Sasaki

    2011-01-01

    Fuel cells are one of the future technologies for marine energy sources. A fuel cell combines hydrogen and oxygen to produce electricity, with water and heat as its by-product. Since the conversion of the fuel to energy takes place via an electrochemical process, the process is clean, quiet and highly efficient. This paper presents the types and characteristics of fuel cells, the status of marine use, and the outline of safety requirements which apply to fuel cell power generation systems.

  16. Modeling Of Proton Exchange Membrane Fuel Cell Systems

    DEFF Research Database (Denmark)

    Nielsen, Mads Pagh

    The objective of this doctoral thesis was to develop reliable steady-state and transient component models suitable to asses-, develop- and optimize proton exchange membrane (PEM) fuel cell systems. Several components in PEM fuel cell systems were characterized and modeled. The developed component......- and system models match experimental data from the literature. However, limited data were available for verification so further work is necessary to confirm detailed aspects of the models. It is nonetheless expected that the developed models will be useful for system modeling and optimization of PEM fuel...... cell systems. Consequences of indirectly fueling PEM stacks with hydrocarbons using reforming technology were investigated using a PEM stack model including CO poisoning kinetics and a transient Simulink steam reforming system model. Aspects regarding the optimization of PEM fuel cell systems...

  17. Miniature Bioreactor System for Long-Term Cell Culture

    Science.gov (United States)

    Gonda, Steve R.; Kleis, Stanley J.; Geffert, Sandara K.

    2010-01-01

    A prototype miniature bioreactor system is designed to serve as a laboratory benchtop cell-culturing system that minimizes the need for relatively expensive equipment and reagents and can be operated under computer control, thereby reducing the time and effort required of human investigators and reducing uncertainty in results. The system includes a bioreactor, a fluid-handling subsystem, a chamber wherein the bioreactor is maintained in a controlled atmosphere at a controlled temperature, and associated control subsystems. The system can be used to culture both anchorage-dependent and suspension cells, which can be either prokaryotic or eukaryotic. Cells can be cultured for extended periods of time in this system, and samples of cells can be extracted and analyzed at specified intervals. By integrating this system with one or more microanalytical instrument(s), one can construct a complete automated analytical system that can be tailored to perform one or more of a large variety of assays.

  18. Neutrophils and macrophages: The main partners of phagocyte cell systems

    Directory of Open Access Journals (Sweden)

    Manuel T. Silva

    2012-07-01

    Full Text Available Biological cellular systems are groups of cells sharing a set of characteristics, mainly key function and origin. Phagocytes are crucial in the host defense against microbial infection. The previously proposed phagocyte cell systems including the most recent and presently prevailing one, the Mononuclear Phagocyte System (MPS, grouped mononuclear cells but excluded neutrophils, creating an unacceptable situation. As neutrophils are archetypical phagocytes that must be members of comprehensive phagocyte systems, M. T. Silva recently proposed the creation of a Myeloid Phagocyte System (MYPS that adds neutrophils to the MPS. The phagocytes grouped in the MYPS include the leukocytes neutrophils, inflammatory monocytes, macrophages and immature myeloid DCs. Here the justifications behind the inclusion of neutrophils in a phagocyte system is expanded and the MYPS are further characterized as a group of dedicated phagocytic cells that function in an interacting and cooperative way in the host defense against microbial infection. Neutrophils and macrophages are considered the main arms of this system.

  19. Onsite Distributed Generation Systems For Laboratories, Laboratories for the 21st Century: Best Practices (Brochure)

    Energy Technology Data Exchange (ETDEWEB)

    2011-09-01

    This guide provides general information on implementing onsite distributed generation systems in laboratory environments. Specific technology applications, general performance information, and cost data are provided to educate and encourage laboratory energy managers to consider onsite power generation or combined heat and power (CHP) systems for their facilities. After conducting an initial screening, energy managers are encouraged to conduct a detailed feasibility study with actual cost and performance data for technologies that look promising. Onsite distributed generation systems are small, modular, decentralized, grid-connected, or off-grid energy systems. These systems are located at or near the place where the energy is used. These systems are also known as distributed energy or distributed power systems. DG technologies are generally considered those that produce less than 20 megawatts (MW) of power. A number of technologies can be applied as effective onsite DG systems, including: (1) Diesel, natural gas, and dual-fuel reciprocating engines; (2) Combustion turbines and steam turbines; (3) Fuel cells; (4) Biomass heating; (5) Biomass combined heat and power; (6) Photovoltaics; and (7) Wind turbines. These systems can provide a number of potential benefits to an individual laboratory facility or campus, including: (1) High-quality, reliable, and potentially dispatchable power; (2) Low-cost energy and long-term utility cost assurance, especially where electricity and/or fuel costs are high; (3) Significantly reduced greenhouse gas (GHG) emissions. Typical CHP plants reduce onsite GHG by 40 to 60 percent; (4) Peak demand shaving where demand costs are high; (5) CHP where thermal energy can be used in addition to electricity; (6) The ability to meet standby power needs, especially where utility-supplied power is interrupted frequently or for long periods and where standby power is required for safety or emergencies; and (7) Use for standalone or off

  20. Two-dimensional diffusion limited system for cell growth

    International Nuclear Information System (INIS)

    Hlatky, L.

    1985-11-01

    A new cell system, the ''sandwich'' system, was developed to supplement multicellular spheroids as tumor analogues. Sandwiches allow new experimental approaches to questions of diffusion, cell cycle effects and radiation resistance in tumors. In this thesis the method for setting up sandwiches is described both theoretically and experimentally followed by its use in x-ray irradiation studies. In the sandwich system, cells are grown in a narrow gap between two glass slides. Where nutrients and waste products can move into or out of the local environment of the cells only by diffusing through the narrow gap between the slides. Due to the competition between cells, self-created gradients of nutrients and metabolic products are set up resulting in a layer of cells which resembles a living spheroid cross section. Unlike the cells of the spheroid, however, cells in all regions of the sandwich are visible. Therefore, the relative sizes of the regions and their time-dependent growth can be monitored visually without fixation or sectioning. The oxygen and nutrient gradients can be ''turned off'' at any time without disrupting the spatial arrangement of the cells by removing the top slide of the assembly and subsequently turned back on if desired. Removal of the top slide also provides access to all the cells, including those near the necrotic center, of the sandwich. The cells can then be removed for analysis outside the sandwich system. 61 refs., 17 figs

  1. Large combined heat and power plants in sustainable energy systems

    DEFF Research Database (Denmark)

    Lund, Rasmus Søgaard; Mathiesen, Brian Vad

    2015-01-01

    In many countries, the electricity supply and power plant operation are challenged by increasing amounts of fluctuating renewable energy sources. A smart energy system should be developed to integrate as much energy supply from fluctuating renewable sources and to utilise the scarce biomass....... It is concluded that the CCGT CHP plant is the most feasible both from a technical analysis and a market economic analysis with electricity exchange. It is found that the current economic framework for large CHP plants in Denmark generates a mismatch between socio economy and business economy as well...... as an unsustainable level of biomass consumption. Therefore, the regulatory framework should generally be considered in long-term planning of sustainable CHP systems....

  2. Programmed cell death in the plant immune system.

    Science.gov (United States)

    Coll, N S; Epple, P; Dangl, J L

    2011-08-01

    Cell death has a central role in innate immune responses in both plants and animals. Besides sharing striking convergences and similarities in the overall evolutionary organization of their innate immune systems, both plants and animals can respond to infection and pathogen recognition with programmed cell death. The fact that plant and animal pathogens have evolved strategies to subvert specific cell death modalities emphasizes the essential role of cell death during immune responses. The hypersensitive response (HR) cell death in plants displays morphological features, molecular architectures and mechanisms reminiscent of different inflammatory cell death types in animals (pyroptosis and necroptosis). In this review, we describe the molecular pathways leading to cell death during innate immune responses. Additionally, we present recently discovered caspase and caspase-like networks regulating cell death that have revealed fascinating analogies between cell death control across both kingdoms.

  3. Situation analysis in relation to district heating and CHP in the Baltic Sea Region: Estonia, Latvia, Lithuania, Poland, Russia, Kaliningrad

    International Nuclear Information System (INIS)

    2000-11-01

    such bodies must be to secure the implementation of national energy policy, and of the acquis communautaire in the countries where this is relevant. Laying out the role gas, district heating and CHP respectively should be a main priority. Institute a continuous dialogue between key political and market actors, to optimise the relation between natural gas, district heating, and condensing power. Its aim should also be to institute measures that will boost investments. (EHS)

  4. A Web-Server of Cell Type Discrimination System

    Directory of Open Access Journals (Sweden)

    Anyou Wang

    2014-01-01

    Full Text Available Discriminating cell types is a daily request for stem cell biologists. However, there is not a user-friendly system available to date for public users to discriminate the common cell types, embryonic stem cells (ESCs, induced pluripotent stem cells (iPSCs, and somatic cells (SCs. Here, we develop WCTDS, a web-server of cell type discrimination system, to discriminate the three cell types and their subtypes like fetal versus adult SCs. WCTDS is developed as a top layer application of our recent publication regarding cell type discriminations, which employs DNA-methylation as biomarkers and machine learning models to discriminate cell types. Implemented by Django, Python, R, and Linux shell programming, run under Linux-Apache web server, and communicated through MySQL, WCTDS provides a friendly framework to efficiently receive the user input and to run mathematical models for analyzing data and then to present results to users. This framework is flexible and easy to be expended for other applications. Therefore, WCTDS works as a user-friendly framework to discriminate cell types and subtypes and it can also be expended to detect other cell types like cancer cells.

  5. A web-server of cell type discrimination system.

    Science.gov (United States)

    Wang, Anyou; Zhong, Yan; Wang, Yanhua; He, Qianchuan

    2014-01-01

    Discriminating cell types is a daily request for stem cell biologists. However, there is not a user-friendly system available to date for public users to discriminate the common cell types, embryonic stem cells (ESCs), induced pluripotent stem cells (iPSCs), and somatic cells (SCs). Here, we develop WCTDS, a web-server of cell type discrimination system, to discriminate the three cell types and their subtypes like fetal versus adult SCs. WCTDS is developed as a top layer application of our recent publication regarding cell type discriminations, which employs DNA-methylation as biomarkers and machine learning models to discriminate cell types. Implemented by Django, Python, R, and Linux shell programming, run under Linux-Apache web server, and communicated through MySQL, WCTDS provides a friendly framework to efficiently receive the user input and to run mathematical models for analyzing data and then to present results to users. This framework is flexible and easy to be expended for other applications. Therefore, WCTDS works as a user-friendly framework to discriminate cell types and subtypes and it can also be expended to detect other cell types like cancer cells.

  6. Enhancing the Energy Efficiency of Wastewater Treatment Plants through Co-digestion and Fuel Cell Systems

    Directory of Open Access Journals (Sweden)

    Marta Gandiglio

    2017-10-01

    Full Text Available The present work provides an overview of technological measures to increase the self-sufficiency of wastewater treatment plants (WWTPs, in particular for the largely diffused activated sludge-based WWTP. The operation of WWTPs entails a huge amount of electricity. Thermal energy is also required for pre-heating the sludge and sometimes exsiccation of the digested sludge. On the other hand, the entering organic matter contained in the wastewater is a source of energy. Organic matter is recovered as sludge, which is digested in large stirred tanks (anaerobic digester to produce biogas. The onsite availability of biogas represents a great opportunity to cover a significant share of WWTP electricity and thermal demands. Especially, biogas can be efficiently converted into electrical energy (and heat via high temperature fuel cell generators. The final part of this work will report a case study based on the use of sewage biogas into a solid oxide fuel cell. However, the efficient biogas conversion in combined heat and power (CHP devices is not sufficient. Self-sufficiency requires a combination of efficient biogas conversion, the maximization the yield of biogas from the organic substrate, and the minimization of the thermal duty connected to the preheating of the sludge feeding the anaerobic digester (generally achieved with pre-thickeners. Finally, the co-digestion of the organic fraction of municipal solid waste (OFMSW into digesters treating sludge from WWTPs represent an additional opportunity for increasing the biogas production of existing WWTPs, thus helping the transition toward self-sufficient plants.

  7. PORTABLE PEM FUEL CELL SYSTEM: WATER AND HEAT MANAGEMENT

    Directory of Open Access Journals (Sweden)

    SITI NAJIBAH ABD RAHMAN

    2016-07-01

    Full Text Available Portable polymer electrolyte membrane (PEM fuel cell power generator is a PEM fuel cell application that is used as an external charger to supply the demand for high energy. Different environments at various ambient temperatures and humidity levels affect the performance of PEM fuel cell power generators. Thermal and water management in portable PEM fuel cells are a critical technical barrier for the commercialization of this technology. The size and weight of the portable PEM fuel cells used for thermal and water management systems that determine the performance of portable PEM fuel cells also need to be considered. The main objective of this paper review was to determine the importance of water and thermal management systems in portable PEM fuel cells. Additionally, this review investigated heat transfer and water transport in PEM fuel cells. Given that portable PEM fuel cells with different powers require different thermal and water management systems, this review also discussed and compared management systems for low-, medium-, and high-power portable PEM fuel cells.

  8. Quadruple or quintuple conversion of hlb, sak, sea (or sep), scn, and chp genes by bacteriophages in non-beta-hemolysin-producing bovine isolates of Staphylococcus aureus.

    Science.gov (United States)

    Kumagai, Rina; Nakatani, Kazue; Ikeya, Nanami; Kito, Yukiko; Kaidoh, Toshio; Takeuchi, Shotaro

    2007-05-16

    In 13 of 43 non-beta-hemolysin-producing bovine isolates of Staphylococcus aureus, two truncated beta-hemolysin (hlb) genes were demonstrated by PCR and sequencing, and one truncated hlb gene was located beside the integrase (int) gene of phage origin. The staphylokinase (sak) gene was detected in all 13 isolates in which the truncated hlb genes were detected by PCR. Enterotoxin A (sea) and enterotoxin P (sep) genes were also detected in 5 and 2 of the 13 isolates, respectively. Moreover, the scn and chp genes encoding staphylococcal complement inhibitor (SCIN) and chemotaxis inhibitory protein of S. aureus (CHIPS) were detected in 13 and 4 of the 13 isolates, respectively. The bacteriophage induced by mitomycin C treatment was able to lysogenize one beta-hemolysin-producing isolate of S. aureus, and the sak and scn genes were detected from the lysogenized isolate. These results suggest quadruple or quintuple conversion of hlb, sak, sea (or sep), scn, and chp genes by bacteriophages among non-beta-hemolysin-producing bovine isolates of S. aureus.

  9. Multi-period MINLP model for optimising operation and structural changes to CHP plants in district heating networks with long-term thermal storage

    International Nuclear Information System (INIS)

    Tveit, Tor-Martin; Savola, Tuula; Gebremedhin, Alemayehu; Fogelholm, Carl-Johan

    2009-01-01

    By using thermal storages it is possible to decouple the generation of power and heat, and it can also lead to an reduction in investments, as the storage can be used to cover the peak load periods. This work presents a MINLP model that can be used for analysing new investments and the long-term operation of CHP plants in a district heating network with long-term thermal storage. The model presented in this work includes the non-linear off-design behaviour of the CHP plants as well as a generic mathematical model of the thermal storage, without the need to fix temperatures and pressure. The model is formulated in such a way that it is suitable for deterministic MINLP solvers. The model is non-convex, and subsequently global optimality cannot be guaranteed with local solvers. In order to reduce the chance of obtaining a poor local optimum compared to the global optimum, the model should be solved many times with the initial values varying randomly. It is possible to extract a lot of results from the model, for instance total annual profit, the optimal selection of process options, mass flow through the plant, and generated power from each plant. The formulation of the model makes it suitable for deterministic MINLP solvers

  10. PDMS/glass microfluidic cell culture system for cytotoxicity tests and cells passage

    DEFF Research Database (Denmark)

    Ziolkowska, K.; Jedrych, E.; Kwapiszewski, R.

    2010-01-01

    In this paper, hybrid (PDMS/glass) microfluidic cell culture system (MCCS) integrated with the concentration gradient generator (CGG) is presented. PDMS gas permeability enabled cells' respiration in the fabricated microdevices and excellent glass hydrophilicity allowed successful cells' seeding......' bioactivity, defining the lowest toxic level of tested substances etc....

  11. A 75-kW methanol reforming fuel cell system

    Energy Technology Data Exchange (ETDEWEB)

    Yan, Xiqiang; Wang, Shudong; Li, Xiangyi; Hou, Ming; Yuan, Zhongshan; Li, Deyi; Pan, Liwei; Zhang, Cheng; Liu, Jingkai; Ming, Pingwen; Yi, Baolian [Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023 (China)

    2006-11-22

    A 75-kW methanol reforming fuel cell system, which consists of a fuel cell system and a methanol auto-thermal reforming fuel processor has been developed at Dalian Institute of Chemical Physics, Chinese Academy of Sciences (CAS). The core of the fuel cell system is a group of CO tolerant PEMFC stacks with a double layer composite structured anode. The fuel cell stacks show good CO tolerance even though 140ppm CO was present in the reformate stream during transients. The auto-thermal reforming (ATR) fuel cell processor could adiabatically produce a suitable reformate without external energy consumption. The output of hydrogen-rich reformate was approximately 120Nm{sup 3}h{sup -1} with a H{sub 2} content near 53% and the CO concentrations generally were under 30ppm. The fuel cell system was integrated with the methanol reforming fuel processor and the peak power output of the fuel cell system exceeded 75kW in testing. The hydrogen utilization approached 70% in the fuel cell system. (author)

  12. Fostering synergy between cell biology and systems biology.

    Science.gov (United States)

    Eddy, James A; Funk, Cory C; Price, Nathan D

    2015-08-01

    In the shared pursuit of elucidating detailed mechanisms of cell function, systems biology presents a natural complement to ongoing efforts in cell biology. Systems biology aims to characterize biological systems through integrated and quantitative modeling of cellular information. The process of model building and analysis provides value through synthesizing and cataloging information about cells and molecules, predicting mechanisms and identifying generalizable themes, generating hypotheses and guiding experimental design, and highlighting knowledge gaps and refining understanding. In turn, incorporating domain expertise and experimental data is crucial for building towards whole cell models. An iterative cycle of interaction between cell and systems biologists advances the goals of both fields and establishes a framework for mechanistic understanding of the genome-to-phenome relationship. Crown Copyright © 2015. Published by Elsevier Ltd. All rights reserved.

  13. Characterization and Modeling of a Methanol Reforming Fuel Cell System

    DEFF Research Database (Denmark)

    Sahlin, Simon Lennart

    topologies is the Reformed Methanol Fuel Cell (RMFC) system that operates on a mix of methanol and water. The fuel is reformed with a steam reforming to a hydrogen rich gas, however with additional formation of Carbon Monoxide and Carbon Dioxide. High Temperature Polymer Electrolyte Membrane Fuel Cell (HT......-PEMFC) has the benefit of being resistant to CO poisoning. The HT-PEM fuel cell operates at elevated temperatures (above 100 oC) and therefore uses phosphoric acid as a proton conductor.  Using a HT-PEMFC in a RMFC system enables the use of exhaust gas from the fuel cell in a catalytic burner which is able...... to heat up the steam reforming process. However, utilizing the excess hydrogen in the system complicates the RMFC system as the amount of hydrogen can vary depending on the fuel methanol supply, fuel cell load and the reformer gas composition. This PhD study has therefore been involved in investigating...

  14. Novel Fuel Cells for Coal Based Systems

    Energy Technology Data Exchange (ETDEWEB)

    Thomas Tao

    2011-12-31

    The goal of this project was to acquire experimental data required to assess the feasibility of a Direct Coal power plant based upon an Electrochemical Looping (ECL) of Liquid Tin Anode Solid Oxide Fuel Cell (LTA-SOFC). The objective of Phase 1 was to experimentally characterize the interaction between the tin anode, coal fuel and cell component electrolyte, the fate of coal contaminants in a molten tin reactor (via chemistry) and their impact upon the YSZ electrolyte (via electrochemistry). The results of this work will provided the basis for further study in Phase 2. The objective of Phase 2 was to extend the study of coal impurities impact on fuel cell components other than electrolyte, more specifically to the anode current collector which is made of an electrically conducting ceramic jacket and broad based coal tin reduction. This work provided a basic proof-of-concept feasibility demonstration of the direct coal concept.

  15. New waste heat district heating system with combined heat and power based on absorption heat exchange cycle in China

    International Nuclear Information System (INIS)

    Sun Fangtian; Fu Lin; Zhang Shigang; Sun Jian

    2012-01-01

    A new waste heat district heating system with combined heat and power based on absorption heat exchange cycle (DHAC) was developed to increase the heating capacity of combined heat and power (CHP) through waste heat recovery, and enhance heat transmission capacity of the existing primary side district heating network through decreasing return water temperature by new type absorption heat exchanger (AHE). The DHAC system and a conventional district heating system based on CHP (CDH) were analyzed in terms of both thermodynamics and economics. Compared to CDH, the DHAC increased heating capacity by 31% and increased heat transmission capacity of the existing primary side district heating network by 75%. The results showed that the exergetic efficiency of DHAC was 10.41% higher and the product exergy monetary cost was 36.6¥/GJ less than a CHD. DHAC is an effective way to increase thermal utilization factor of CHP, and to reduce district heating cost. - Highlights: ► Absorption heat pumps are used to recover waste heat in CHP. ► Absorption heat exchanger can reduce exergy loss in the heat transfer process. ► New waste heat heating system (DHAC) can increase heating capacity of CHP by 31%. ► DHAC can enhance heat transmission capacity of the primary pipe network by 75%. ► DHAC system has the higher exergetic efficiency and the better economic benefit.

  16. A review of fuel cell systems for maritime applications

    Science.gov (United States)

    van Biert, L.; Godjevac, M.; Visser, K.; Aravind, P. V.

    2016-09-01

    Progressing limits on pollutant emissions oblige ship owners to reduce the environmental impact of their operations. Fuel cells may provide a suitable solution, since they are fuel efficient while they emit few hazardous compounds. Various choices can be made with regard to the type of fuel cell system and logistic fuel, and it is unclear which have the best prospects for maritime application. An overview of fuel cell types and fuel processing equipment is presented, and maritime fuel cell application is reviewed with regard to efficiency, gravimetric and volumetric density, dynamic behaviour, environmental impact, safety and economics. It is shown that low temperature fuel cells using liquefied hydrogen provide a compact solution for ships with a refuelling interval up to a tens of hours, but may result in total system sizes up to five times larger than high temperature fuel cells and more energy dense fuels for vessels with longer mission requirements. The expanding infrastructure of liquefied natural gas and development state of natural gas-fuelled fuel cell systems can facilitate the introduction of gaseous fuels and fuel cells on ships. Fuel cell combined cycles, hybridisation with auxiliary electricity storage systems and redundancy improvements are identified as topics for further study.

  17. Development of a microfluidic perfusion 3D cell culture system

    Science.gov (United States)

    Park, D. H.; Jeon, H. J.; Kim, M. J.; Nguyen, X. D.; Morten, K.; Go, J. S.

    2018-04-01

    Recently, 3-dimensional in vitro cell cultures have gained much attention in biomedical sciences because of the closer relevance between in vitro cell cultures and in vivo environments. This paper presents a microfluidic perfusion 3D cell culture system with consistent control of long-term culture conditions to mimic an in vivo microenvironment. It consists of two sudden expansion reservoirs to trap incoming air bubbles, gradient generators to provide a linear concentration, and microchannel mixers. Specifically, the air bubbles disturb a flow in the microfluidic channel resulting in the instability of the perfusion cell culture conditions. For long-term stable operation, the sudden expansion reservoir is designed to trap air bubbles by using buoyancy before they enter the culture system. The performance of the developed microfluidic perfusion 3D cell culture system was examined experimentally and compared with analytical results. Finally, it was applied to test the cytotoxicity of cells infected with Ewing’s sarcoma. Cell death was observed for different concentrations of H2O2. For future work, the developed microfluidic perfusion 3D cell culture system can be used to examine the behavior of cells treated with various drugs and concentrations for high-throughput drug screening.

  18. The influence of operating temperature on the efficiency of a combined heat and power fuel cell plant

    Science.gov (United States)

    Au, S. F.; McPhail, S. J.; Woudstra, N.; Hemmes, K.

    It is generally accepted that the ideal operating temperature of a molten carbonate fuel cell (MCFC) is 650 °C. Nevertheless, when waste heat utilization in the form of an expander and steam production cycle is introduced in the system, another temperature level might prove more productive. This article is a first attempt to the optimization of MCFC operating temperatures of a MCFC system by presenting a case study in which the efficiency of a combined heat and power (CHP) plant is analyzed. The fuel cell plant under investigation is designed around a 250 kW-class MCFC fuelled by natural gas, which is externally reformed by a heat exchange reformer (HER). The operating temperature of the MCFC is varied over a temperature range between 600 and 700 °C while keeping the rest of the system the same as far as possible. Changes in energetic efficiency are given and the causes of these changes are further analyzed. Furthermore, the exergetic efficiencies of the system and the distribution of exergy losses in the system are given. Flowsheet calculations show that there is little dependency on the temperature in the first order. Both the net electrical performance and the overall exergetic performance show a maximum at approximately 675 °C, with an electrical efficiency of 51.9% (LHV), and an exergy efficiency of 58.7%. The overall thermal efficiency of this CHP plant increases from 87.1% at 600 °C to 88.9% at 700 °C. Overall, the change in performance is small in this typical range of MCFC operating temperature.

  19. Heat savings in energy systems with substantial distributed generation

    DEFF Research Database (Denmark)

    Østergaard, PA

    2003-01-01

    . A lowered district heating demand and thereby lowered CHP-bound electricity generation would appear to increase the possibility of integration wind power but due to the ancillary services supplied by CHP plants, the situation is in fact the opposite. Heat savings may not be technically feasible......, if a certain production is required regardless of whether over-all electricity generation is sufficient. This article analyses this and although heat savings do have a negative impact on the amount of wind power the system may integrate a given moment in certain cases, associated fuel savings are notable......In Denmark, the integration of wind power is affected by a large amount of cogeneration of heat and power. With ancillary services supplied by large-scale condensation and combined heat and power (CHP) plants, a certain degree of large-scale generation is required regardless of momentary wind input...

  20. External determinants for the adoption of stationary fuel cells-Infrastructure and policy issues

    International Nuclear Information System (INIS)

    Karger, Cornelia R.; Bongartz, Richard

    2008-01-01

    This paper investigates the relevance of external determinants for the adoption of stationary fuel cells (FCs) by different user groups with respect to the marketability of this innovative technology. FCs allow electricity and heat to be decentrally generated in an energy-efficient and potentially environmentally friendly manner. European energy policy is undertaking efforts to increase the proportion of combined heat and power (CHP) plants. A series of studies have spoken of their considerable market potential. A qualitative study was conducted with six focus groups consisting of 49 commercial users and six focus groups with 54 private consumers. The results of the study show that the specific infrastructure required for decentralisation and policy issues are highly relevant for the user adoption of FCs. Security of supply when energy generation is more strongly decentralised, reliable maintenance of the system, and clear political objectives are examples of factors that are considered essential prerequisites for the adoption of this technology

  1. Usability and Applicability of Microfluidic Cell Culture Systems

    DEFF Research Database (Denmark)

    Hemmingsen, Mette

    of the microfluidic perfusion cell culture system is shown by investigation of adipose-derived stem cell (ASC) differentiation into adipocytes, where we have revealed that paracrine/autocrine signaling is involved in differentiation of a population of ASCs into adipocytes. We have thereby demonstrated......Microfluidic cell culture has been a research area with great attention the last decade due to its potential to mimic the in vivo cellular environment more closely compared to what is possible by conventional cell culture methods. Many exciting and complex devices have been presented providing...... possibilities for, for example, precise control of the chemical environment, 3D cultures, controlled co-culture of different cell types or automated, individual control of up to 96 cell culture chambers in one integrated system. Despite the great new opportunities to perform novel experimental designs...

  2. High concentration photovoltaic systems applying III-V cells

    International Nuclear Information System (INIS)

    Zubi, Ghassan; Bernal-Agustin, Jose L.; Fracastoro, Gian Vincenzo

    2009-01-01

    High concentration systems make use of the direct solar beam and therefore are suitable for application in regions with high annual direct irradiation values. III-V PV cells with a nominal efficiency of up to 39% are readily available in today's market, with further efficiency improvements expected in the years ahead. The relatively high cost of III-V cells limits their terrestrial use to applications under high concentration, usually above 400 suns. In this way the relatively high cell cost is compensated through the low amount for cells needed per kW nominal system output. This paper presents a state of the art of high concentration photovoltaics using III-V cells. This PV field accounts already for more than 20 developed systems, which are commercially available or shortly before market introduction. (author)

  3. Ultra Clean 1.1MW High Efficiency Natural Gas Engine Powered System

    Energy Technology Data Exchange (ETDEWEB)

    Zurlo, James; Lueck, Steve

    2011-08-31

    Dresser, Inc. (GE Energy, Waukesha gas engines) will develop, test, demonstrate, and commercialize a 1.1 Megawatt (MW) natural gas fueled combined heat and power reciprocating engine powered package. This package will feature a total efficiency > 75% and ultra low CARB permitting emissions. Our modular design will cover the 1 – 6 MW size range, and this scalable technology can be used in both smaller and larger engine powered CHP packages. To further advance one of the key advantages of reciprocating engines, the engine, generator and CHP package will be optimized for low initial and operating costs. Dresser, Inc. will leverage the knowledge gained in the DOE - ARES program. Dresser, Inc. will work with commercial, regulatory, and government entities to help break down barriers to wider deployment of CHP. The outcome of this project will be a commercially successful 1.1 MW CHP package with high electrical and total efficiency that will significantly reduce emissions compared to the current central power plant paradigm. Principal objectives by phases for Budget Period 1 include: • Phase 1 – market study to determine optimum system performance, target first cost, lifecycle cost, and creation of a detailed product specification. • Phase 2 – Refinement of the Waukesha CHP system design concepts, identification of critical characteristics, initial evaluation of technical solutions, and risk mitigation plans. Background

  4. Development of a stained cell nuclei counting system

    Science.gov (United States)

    Timilsina, Niranjan; Moffatt, Christopher; Okada, Kazunori

    2011-03-01

    This paper presents a novel cell counting system which exploits the Fast Radial Symmetry Transformation (FRST) algorithm [1]. The driving force behind our system is a research on neurogenesis in the intact nervous system of Manduca Sexta or the Tobacco Hornworm, which was being studied to assess the impact of age, food and environment on neurogenesis. The varying thickness of the intact nervous system in this species often yields images with inhomogeneous background and inconsistencies such as varying illumination, variable contrast, and irregular cell size. For automated counting, such inhomogeneity and inconsistencies must be addressed, which no existing work has done successfully. Thus, our goal is to devise a new cell counting algorithm for the images with non-uniform background. Our solution adapts FRST: a computer vision algorithm which is designed to detect points of interest on circular regions such as human eyes. This algorithm enhances the occurrences of the stained-cell nuclei in 2D digital images and negates the problems caused by their inhomogeneity. Besides FRST, our algorithm employs standard image processing methods, such as mathematical morphology and connected component analysis. We have evaluated the developed cell counting system with fourteen digital images of Tobacco Hornworm's nervous system collected for this study with ground-truth cell counts by biology experts. Experimental results show that our system has a minimum error of 1.41% and mean error of 16.68% which is at least forty-four percent better than the algorithm without FRST.

  5. Conceptual Challenges of the Systemic Approach in Understanding Cell Differentiation.

    Science.gov (United States)

    Paldi, Andras

    2018-01-01

    The cells of a multicellular organism are derived from a single zygote and genetically identical. Yet, they are phenotypically very different. This difference is the result of a process commonly called cell differentiation. How the phenotypic diversity emerges during ontogenesis or regeneration is a central and intensely studied but still unresolved issue in biology. Cell biology is facing conceptual challenges that are frequently confused with methodological difficulties. How to define a cell type? What stability or change means in the context of cell differentiation and how to deal with the ubiquitous molecular variations seen in the living cells? What are the driving forces of the change? We propose to reframe the problem of cell differentiation in a systemic way by incorporating different theoretical approaches. The new conceptual framework is able to capture the insights made at different levels of cellular organization and considered previously as contradictory. It also provides a formal strategy for further experimental studies.

  6. The ubiquitin-proteasome system in glioma cell cycle control

    Directory of Open Access Journals (Sweden)

    Vlachostergios Panagiotis J

    2012-07-01

    Full Text Available Abstract A major determinant of cell fate is regulation of cell cycle. Tight regulation of this process is lost during the course of development and progression of various tumors. The ubiquitin-proteasome system (UPS constitutes a universal protein degradation pathway, essential for the consistent recycling of a plethora of proteins with distinct structural and functional roles within the cell, including cell cycle regulation. High grade tumors, such as glioblastomas have an inherent potential of escaping cell cycle control mechanisms and are often refractory to conventional treatment. Here, we review the association of UPS with several UPS-targeted proteins and pathways involved in regulation of the cell cycle in malignant gliomas, and discuss the potential role of UPS inhibitors in reinstitution of cell cycle control.

  7. Regeneration of hair cells in the mammalian vestibular system.

    Science.gov (United States)

    Li, Wenyan; You, Dan; Chen, Yan; Chai, Renjie; Li, Huawei

    2016-06-01

    Hair cells regenerate throughout the lifetime of non-mammalian vertebrates, allowing these animals to recover from hearing and balance deficits. Such regeneration does not occur efficiently in humans and other mammals. Thus, balance deficits become permanent and is a common sensory disorder all over the world. Since Forge and Warchol discovered the limited spontaneous regeneration of vestibular hair cells after gentamicininduced damage in mature mammals, significant efforts have been exerted to trace the origin of the limited vestibular regeneration in mammals after hair cell loss. Moreover, recently many strategies have been developed to promote the hair cell regeneration and subsequent functional recovery of the vestibular system, including manipulating the Wnt, Notch and Atoh1. This article provides an overview of the recent advances in hair cell regeneration in mammalian vestibular epithelia. Furthermore, this review highlights the current limitations of hair cell regeneration and provides the possible solutions to regenerate functional hair cells and to partially restore vestibular function.

  8. Horizontally rotated cell culture system with a coaxial tubular oxygenator

    Science.gov (United States)

    Wolf, David A. (Inventor); Schwarz, Ray P. (Inventor); Trinh, Tinh T. (Inventor)

    1991-01-01

    The present invention relates to a horizontally rotating bioreactor useful for carrying out cell and tissue culture. For processing of mammalian cells, the system is sterilized and fresh fluid medium, microcarrier beads, and cells are admitted to completely fill the cell culture vessel. An oxygen containing gas is admitted to the interior of the permeable membrane which prevents air bubbles from being introduced into the medium. The cylinder is rotated at a low speed within an incubator so that the circular motion of the fluid medium uniformly suspends the microbeads throughout the cylinder during the cell growth period. The unique design of this cell and tissue culture device was initially driven by two requirements imposed by its intended use for feasibility studies for three dimensional culture of living cells and tissues in space by JSC. They were compatible with microgravity and simulation of microgravity in one G. The vessels are designed to approximate the extremely quiescent low shear environment obtainable in space.

  9. Immunoregulation of NKT Cells in Systemic Lupus Erythematosus.

    Science.gov (United States)

    Chen, Junwei; Wu, Meng; Wang, Jing; Li, Xiaofeng

    2015-01-01

    Systemic lupus erythematosus (SLE) is a multisystem autoimmune disease with different variety of clinical manifestations. Natural killer T (NKT) cells are innate lymphocytes that play a regulatory role during broad range of immune responses. A number of studies demonstrated that the quantity and quality of invariant NKT (iNKT) cells showed marked defects in SLE patients in comparison to healthy controls. This finding suggests that iNKT cells may play a regulatory role in the occurrence and development of this disease. In this review, we mainly summarized the most recent findings about the behavior of NKT cells in SLE patients and mouse models, as well as how NKT cells affect the proportion of T helper cells and the production of autoreactive antibodies in the progress of SLE. This will help people better understand the role of NKT cells in the development of SLE and improve the therapy strategy.

  10. Multivariable control system for dynamic PEM fuel cell model

    International Nuclear Information System (INIS)

    Tanislav, Vasile; Carcadea, Elena; Capris, Catalin; Culcer, Mihai; Raceanu, Mircea

    2010-01-01

    Full text: The main objective of this work was to develop a multivariable control system of robust type for a PEM fuel cells assembly. The system will be used in static and mobile applications for different values of power, generated by a fuel cell assembly of up to 10 kW. Intermediate steps were accomplished: a study of a multivariable control strategy for a PEM fuel cell assembly; a mathematic modeling of mass and heat transfer inside of fuel cell assembly, defining the response function to hydrogen and oxygen/air mass flow and inlet pressure changes; a testing stand for fuel cell assembly; experimental determinations of transient response for PEM fuel cell assembly, and more others. To define the multivariable control system for a PEM fuel cell assembly the parameters describing the system were established. Also, there were defined the generic mass and energy balance equations as functions of derivative of m i , in and m i , out , representing the mass going into and out from the fuel cell, while Q in is the enthalpy and Q out is the enthalpy of the unused reactant gases and heat produced by the product, Q dis is the heat dissipated to the surroundings, Q c is the heat taken away from the stack by active cooling and W el is the electricity generated. (authors)

  11. Method of operating a direct dme fuel cell system

    DEFF Research Database (Denmark)

    2011-01-01

    The present invention relates to a method of operating a fuel cell system comprising one or more fuel cells with a proton exchange membrane, wherein the membrane is composed of a polymeric material comprising acid-doped polybenzimidazole (PBI). The method comprises adjusting the operating...

  12. Circulating cell free DNA as a predictor of systemic lupus ...

    African Journals Online (AJOL)

    Circulating cell free DNA as a predictor of systemic lupus erythematosus severity and monitoring of therapy. Olfat M. Hendy, Tawfik Abdel Motalib, Mona A. El Shafie, Fatma A. Khalaf, Sobhy E. Kotb, Aziza Khalil, Salwa R. Ali ...

  13. Integrating fuel cell power systems into building physical plants

    Energy Technology Data Exchange (ETDEWEB)

    Carson, J. [KCI Technologies, Inc., Hunt Valley, MD (United States)

    1996-12-31

    This paper discusses the integration of fuel cell power plants and absorption chillers to cogenerate chilled water or hot water/steam for all weather air conditioning as one possible approach to building system applications. Absorption chillers utilize thermal energy in an absorption based cycle to chill water. It is feasible to use waste heat from fuel cells to provide hydronic heating and cooling. Performance regimes will vary as a function of the supply and quality of waste heat. Respective performance characteristics of fuel cells, absorption chillers and air conditioning systems will define relationships between thermal and electrical load capacities for the combined systems. Specifically, this paper develops thermodynamic relationships between bulk electrical power and cooling/heating capacities for combined fuel cell and absorption chiller system in building applications.

  14. Methane-Oxygen Solid Oxide Fuel Cell System, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — NASA has a defined need for energy dense and highly efficient energy storage and power delivery systems for future space missions. Compared to other fuel cell...

  15. Immobilized yeast cell systems for continuous fermentation applications.

    Science.gov (United States)

    Verbelen, Pieter J; De Schutter, David P; Delvaux, Filip; Verstrepen, Kevin J; Delvaux, Freddy R

    2006-10-01

    In several yeast-related industries, continuous fermentation systems offer important economical advantages in comparison with traditional systems. Fermentation rates are significantly improved, especially when continuous fermentation is combined with cell immobilization techniques to increase the yeast concentration in the fermentor. Hence the technique holds a great promise for the efficient production of fermented beverages, such as beer, wine and cider as well as bio-ethanol. However, there are some important pitfalls, and few industrial-scale continuous systems have been implemented. Here, we first review the various cell immobilization techniques and reactor setups. Then, the impact of immobilization on cell physiology and fermentation performance is discussed. In a last part, we focus on the practical use of continuous fermentation and cell immobilization systems for beer production.

  16. The Mast Cell, Contact, and Coagulation System Connection in Anaphylaxis

    Directory of Open Access Journals (Sweden)

    Mar Guilarte

    2017-07-01

    Full Text Available Anaphylaxis is the most severe form of allergic reaction, resulting from the effect of mediators and chemotactic substances released by activated cells. Mast cells and basophils are considered key players in IgE-mediated human anaphylaxis. Beyond IgE-mediated activation of mast cells/basophils, further mechanisms are involved in the occurrence of anaphylaxis. New insights into the potential relevance of pathways other than mast cell and basophil degranulation have been unraveled, such as the activation of the contact and the coagulation systems. Mast cell heparin released upon activation provides negatively charged surfaces for factor XII (FXII binding and auto-activation. Activated FXII, the initiating serine protease in both the contact and the intrinsic coagulation system, activates factor XI and prekallikrein, respectively. FXII-mediated bradykinin (BK formation has been proven in the human plasma of anaphylactic patients as well as in experimental models of anaphylaxis. Moreover, the severity of anaphylaxis is correlated with the increase in plasma heparin, BK formation and the intensity of contact system activation. FXII also activates plasminogen in the fibrinolysis system. Mast cell tryptase has been shown to participate in fibrinolysis through plasmin activation and by facilitating the degradation of fibrinogen. Some usual clinical manifestations in anaphylaxis, such as angioedema or hypotension, or other less common, such as metrorrhagia, may be explained by the direct effect of the activation of the coagulation and contact system driven by mast cell mediators.

  17. Systems immunology allows a new view on human dendritic cells.

    Science.gov (United States)

    Schultze, Joachim L; Aschenbrenner, Anna C

    2018-02-24

    As the most important antigen-presenting cells, dendritic cells connect the innate and adaptive part of our immune system and play a pivotal role in our course of action against invading pathogens as well as during successful vaccination. Immunologists have therefore studied these cells in great detail using flow cytometry-based analyses, in vitro assays and in vivo models, both in murine models and in humans. Albeit, sophisticated, classical immunological, and molecular approaches were often unable to unequivocally determine the subpopulation structure of the dendritic cell lineage and not surprisingly, conflicting results about dendritic cell subsets co-existed throughout the last decades. With the advent of systems approaches and the most recent introduction of -omics approaches on the single cell level combined with multi-colour flow cytometry or mass cytometry, we now enter an era allowing us to define cell population structures with an unprecedented precision. We will report here on the most recent studies applying these technologies to human dendritic cells. Proper delineation of and definition of molecular signatures for the different human dendritic cell subsets will greatly facilitate studying these cells in the future: understanding their function under physiological as well as pathological conditions. Copyright © 2018 Elsevier Ltd. All rights reserved.

  18. Solar cells: Operating principles, technology, and system applications

    Science.gov (United States)

    Green, M. A.

    Solar cell theory, materials, fabrication, design, modules, and systems are discussed. The solar source of light energy is described and quantified, along with a review of semiconductor properties and the generation, recombination, and the basic equations of photovoltaic device physics. Particular attention is given to p-n junction diodes, including efficiency limits, losses, and measurements. Si solar cell technology is described for the production of solar-quality crystals and wafers, and design, improvements, and device structures are examined. Consideration is given to alternate semiconductor materials and applications in concentrating systems, storage, and the design and construction of stand-alone systems and systems for residential and centralized power generation.

  19. A solid oxide fuel cell system for buildings

    International Nuclear Information System (INIS)

    Zink, Florian; Lu, Yixin; Schaefer, Laura

    2007-01-01

    This paper examines an integrated solid oxide fuel cell (SOFC) absorption heating and cooling system used for buildings. The integrated system can provide heating/cooling and/or hot water for buildings while consuming natural gas. The aim of this study is to give an overall description of the system. The possibility of such an integrated system is discussed and the configuration of the system is described. A system model is presented, and a specific case study of the system, which consists of a pre-commercial SOFC system and a commercial LiBr absorption system, is performed. In the case study, the detailed configuration of an integrated system is given, and the heat and mass balance and system performance are obtained through numerical calculation. Based on the case study, some considerations with respect to system component selection, system configuration and design are discussed. Additionally, the economic and environmental issues of this specific system are evaluated briefly. The results show that the combined system demonstrates great advantages in both technical and environmental aspects. With the present development trends in solid oxide fuel cells and the commercial status of absorption heating and cooling systems, it is very likely that such a combined system will become increasingly feasible within the following decade

  20. Muscle Stem Cells: A Model System for Adult Stem Cell Biology.

    Science.gov (United States)

    Cornelison, Ddw; Perdiguero, Eusebio

    2017-01-01

    Skeletal muscle stem cells, originally termed satellite cells for their position adjacent to differentiated muscle fibers, are absolutely required for the process of skeletal muscle repair and regeneration. In the last decade, satellite cells have become one of the most studied adult stem cell systems and have emerged as a standard model not only in the field of stem cell-driven tissue regeneration but also in stem cell dysfunction and aging. Here, we provide background in the field and discuss recent advances in our understanding of muscle stem cell function and dysfunction, particularly in the case of aging, and the potential involvement of muscle stem cells in genetic diseases such as the muscular dystrophies.

  1. Changes in cell adhesion molecule expression on T cells associated with systemic virus infection

    DEFF Research Database (Denmark)

    Andersson, E C; Christensen, Jan Pravsgaard; Marker, O

    1994-01-01

    analyses showed that T cells with a changed adhesion molecule profile tended to present other cell surface markers indicating a state of cellular activation, e.g., IL-2R, and included all virus-specific CTL effectors. Regarding the physiologic significance of these changes in adhesion molecule expression......Virus-induced changes in adhesion molecule expression on T cells were investigated to understand how antiviral effector cells migrate into infectious foci. FACS analysis revealed that after systemic infection with lymphocytic choriomeningitis virus a number of cell adhesion molecules, including VLA...

  2. Changes in cell adhesion molecule expression on T cells associated with systemic virus infection

    DEFF Research Database (Denmark)

    Andersson, E C; Christensen, Jan Pravsgaard; Marker, O

    1994-01-01

    Virus-induced changes in adhesion molecule expression on T cells were investigated to understand how antiviral effector cells migrate into infectious foci. FACS analysis revealed that after systemic infection with lymphocytic choriomeningitis virus a number of cell adhesion molecules, including VLA...... analyses showed that T cells with a changed adhesion molecule profile tended to present other cell surface markers indicating a state of cellular activation, e.g., IL-2R, and included all virus-specific CTL effectors. Regarding the physiologic significance of these changes in adhesion molecule expression...

  3. THE PROGRAMED CELL DEATH REGULATORS OF ISOLATED MODEL SYSTEMS

    Directory of Open Access Journals (Sweden)

    D. V. Vatlitsov

    2016-06-01

    Full Text Available The technology evolution creates the prerequisites for the emergence of new informational concept and approaches to the formation of a fundamentally new principles of biological objects understanding. The aim was to study the activators of the programmed cell death in an isolated system model. Cell culture aging parameters were performed on flow cytometer. It had formed the theory that the changes in the concentrations of metal ions and increase their extracellular concentration had formed a negative gradient into the cells.regulation of cell death. It was shown that the metals ions concentrations.

  4. Power conditioning of fuel cell systems in portable applications

    Energy Technology Data Exchange (ETDEWEB)

    Brey, J.J.; Bordallo, C.R. [Hynergreen Technologies S.A. Avenida de la Buhaira, 2. 41018 SEVILLE (Spain); Carrasco, J.M.; Galvan, E.; Jimenez, A. [School of Engineering, University of Seville, Camino de los Descubrimientos s/n. 41092 SEVILLE (Spain); Moreno, E. [Instalaciones Inabensa S.A., c/Manuel Velasco Pando no. 7, 41007, SEVILLE (Spain)

    2007-07-15

    Fuel cells are emerging as main power source for portable applications. These devices need power management circuit to connect varying output fuel cell voltage to desired regulated voltage load with high efficiency. Maintaining high efficiency of the converter over a wide loading range can improve stored fuel longevity. The purpose of this paper is to report a general review of most used topologies in fuel cell power conditioning applied to portable systems. Finally, a 100 W DC-DC converter for a particular fuel cell portable application will be presented. This converter was designed to fulfill several specifications of input and output voltage. (author)

  5. A review of decellularized stem cell matrix: a novel cell expansion system for cartilage tissue engineering

    Directory of Open Access Journals (Sweden)

    M Pei

    2011-11-01

    Full Text Available Cell-based therapy is a promising biological approach for the treatment of cartilage defects. Due to the small size of autologous cartilage samples available for cell transplantation in patients, cells need to be expanded to yield a sufficient cell number for cartilage repair. However, chondrocytes and adult stem cells tend to become replicatively senescent once they are expanded on conventional plastic flasks. Many studies demonstrate that the loss of cell properties is concomitant with the decreased cell proliferation capacity. This is a significant challenge for cartilage tissue engineering and regeneration. Despite much progress having been made in cell expansion, there are still concerns over expanded cell size and quality for cell transplantation applications. Recently, in vivo investigations in stem cell niches have suggested the importance of developing an in vitro stem cell microenvironment for cell expansion and tissue-specific differentiation. Our and other investigators’ work indicates that a decellularized stem cell matrix (DSCM may provide such an expansion system to yield large-quantity and high-quality cells for cartilage tissue engineering and regeneration. This review briefly introduces key parameters in an in vivo stem cell niche and focuses on our recent work on DSCM for its rejuvenating or reprograming effect on various adult stem cells and chondrocytes. Since research in DSCM is still in its infancy, we are only able to discuss some potential mechanisms of DSCM on cell proliferation and chondrogenic potential. Further investigations of the underlying mechanism and in vivo regeneration capacity will allow this approach to be used in clinics.

  6. PhysiCell: An open source physics-based cell simulator for 3-D multicellular systems.

    Science.gov (United States)

    Ghaffarizadeh, Ahmadreza; Heiland, Randy; Friedman, Samuel H; Mumenthaler, Shannon M; Macklin, Paul

    2018-02-01

    Many multicellular systems problems can only be understood by studying how cells move, grow, divide, interact, and die. Tissue-scale dynamics emerge from systems of many interacting cells as they respond to and influence their microenvironment. The ideal "virtual laboratory" for such multicellular systems simulates both the biochemical microenvironment (the "stage") and many mechanically and biochemically interacting cells (the "players" upon the stage). PhysiCell-physics-based multicellular simulator-is an open source agent-based simulator that provides both the stage and the players for studying many interacting cells in dynamic tissue microenvironments. It builds upon a multi-substrate biotransport solver to link cell phenotype to multiple diffusing substrates and signaling factors. It includes biologically-driven sub-models for cell cycling, apoptosis, necrosis, solid and fluid volume changes, mechanics, and motility "out of the box." The C++ code has minimal dependencies, making it simple to maintain and deploy across platforms. PhysiCell has been parallelized with OpenMP, and its performance scales linearly with the number of cells. Simulations up to 105-106 cells are feasible on quad-core desktop workstations; larger simulations are attainable on single HPC compute nodes. We demonstrate PhysiCell by simulating the impact of necrotic core biomechanics, 3-D geometry, and stochasticity on the dynamics of hanging drop tumor spheroids and ductal carcinoma in situ (DCIS) of the breast. We demonstrate stochastic motility, chemical and contact-based interaction of multiple cell types, and the extensibility of PhysiCell with examples in synthetic multicellular systems (a "cellular cargo delivery" system, with application to anti-cancer treatments), cancer heterogeneity, and cancer immunology. PhysiCell is a powerful multicellular systems simulator that will be continually improved with new capabilities and performance improvements. It also represents a significant

  7. Bringing fuel cells to reality and reality to fuel cells: A systems perspective on the use of fuel cells

    International Nuclear Information System (INIS)

    Saxe, Maria

    2008-10-01

    The hopes and expectations on fuel cells are high and sometimes unrealistically positive. However, as an emerging technology, much remains to be proven and the proper use of the technology in terms of suitable applications, integration with society and extent of use is still under debate. This thesis is a contribution to the debate, presenting results from two fuel cell demonstration projects, looking into the introduction of fuel cells on the market, discussing the prospects and concerns for the near-term future and commenting on the potential use in a future sustainable energy system. Bringing fuel cells to reality implies finding near-term niche applications and markets where fuel cell systems may be competitive. In a sense fuel cells are already a reality as they have been demonstrated in various applications world-wide. However, in many of the envisioned applications fuel cells are far from being competitive and sometimes also the environmental benefit of using fuel cells in a given application may be questioned. Bringing reality to fuel cells implies emphasising the need for realistic expectations and pointing out that the first markets have to be based on the currently available technology and not the visions of what fuel cells could be in the future. The results from the demonstration projects show that further development and research on especially the durability for fuel cell systems is crucial and a general recommendation is to design the systems for high reliability and durability rather than striving towards higher energy efficiencies. When sufficient reliability and durability are achieved, fuel cell systems may be introduced in niche markets where the added values presented by the technology compensate for the initial high cost

  8. Design of a Fuel Cell Hybrid Electric Vehicle Drive System

    DEFF Research Database (Denmark)

    Schaltz, Erik

    Fuel cells achieve more and more attention due to their potential of replacing the traditional internal combustion engine (ICE) used in the area of transportation. In this PhD thesis a fuel cell shaft power pack (FCSPP) is designed and implemented in a small truck. The FCSPP replaces the original...... supply system of the truck which was powered by a lead-acid battery package. The FCSPP includes fuel storage, a fuel cell system, an energy storage device, power electronics, an electric machine, and the necessary control. The FCSPP therefore converts the energy of the fuel to a shaft torque and speed...... of the electric machine. In the thesis the High Temperature Proton Exchange Membrane Fuel Cell (HTPEMFC) is used as it has promising properties for being supplied by reformed methanol, instead of pure hydrogen, which is more practical feasible. It takes approximately 6 minutes before the fuel cell is ready...

  9. Design and Control of High Temperature PEM Fuel Cell System

    DEFF Research Database (Denmark)

    Andreasen, Søren Juhl

    demands for this. A 1kW fuel cell stack with optimized  ow plates was heated in 5 minutes using the introduction of an electrical air pre-heater. Using pure hydrogen in compressed form is problematic due to the very small density of hydrogen, even at high pressures. Hydrogen is a very energy e-cient gas...... enables the use of designing cathode air cooled stacks greatly simplifying the fuel cell system and lowering the parasitic losses. Furthermore, the fuel impurity tolerance is signicantly improved because of the higher temperatures, and much higher concentrations of CO can be endured without performance...... or life time losses. In order to evaluate the performance of using HTPEM fuel cells for electricity production in electrical applications, a 400 W fuel cell system is initially designed using a cathode air cooled 30 cell HTPEM stack. The stack runs on pure hydrogen in a deadend anode configuration...

  10. Clinical Application of Stem Cells in the Cardiovascular System

    Science.gov (United States)

    Stamm, Christof; Klose, Kristin; Choi, Yeong-Hoon

    Regenerative medicine encompasses "tissue engineering" - the in vitro fabrication of tissues and/or organs using scaffold material and viable cells - and "cell therapy" - the transplantation or manipulation of cells in diseased tissue in vivo. In the cardiovascular system, tissue engineering strategies are being pursued for the development of viable replacement blood vessels, heart valves, patch material, cardiac pacemakers and contractile myocardium. Anecdotal clinical applications of such vessels, valves and patches have been described, but information on systematic studies of the performance of such implants is not available, yet. Cell therapy for cardiovascular regeneration, however, has been performed in large series of patients, and numerous clinical studies have produced sometimes conflicting results. The purpose of this chapter is to summarize the clinical experience with cell therapy for diseases of the cardiovascular system, and to analyse possible factors that may influence its outcome.

  11. Analysis and Design of Fuel Cell Systems for Aviation

    Directory of Open Access Journals (Sweden)

    Thomas Kadyk

    2018-02-01

    Full Text Available In this paper, the design of fuel cells for the main energy supply of passenger transportation aircraft is discussed. Using a physical model of a fuel cell, general design considerations are derived. Considering different possible design objectives, the trade-off between power density and efficiency is discussed. A universal cost–benefit curve is derived to aid the design process. A weight factor w P is introduced, which allows incorporating technical (e.g., system mass and efficiency as well as non-technical design objectives (e.g., operating cost, emission goals, social acceptance or technology affinity, political factors. The optimal fuel cell design is not determined by the characteristics of the fuel cell alone, but also by the characteristics of the other system components. The fuel cell needs to be designed in the context of the whole energy system. This is demonstrated by combining the fuel cell model with simple and detailed design models of a liquid hydrogen tank. The presented methodology and models allows assessing the potential of fuel cell systems for mass reduction of future passenger aircraft.

  12. Portable direct methanol fuel cell systems

    Science.gov (United States)

    Narayanan, S. R.; Valdez, T. I.

    2002-01-01

    This article includes discussion of the specific power and power density requirements for various portable system applications, the status of stack technology, progress in the implementation of balance-of-plant designs, and a summary of the characteristics of various DMFC portable power source demonstrations.

  13. Direct methanol fuel cell and system

    Science.gov (United States)

    Wilson, Mahlon S.

    2004-10-26

    A fuel cell having an anode and a cathode and a polymer electrolyte membrane located between anode and cathode gas diffusion backings uses a methanol vapor fuel supply. A permeable polymer electrolyte membrane having a permeability effective to sustain a carbon dioxide flux equivalent to at least 10 mA/cm.sup.2 provides for removal of carbon dioxide produced at the anode by reaction of methanol with water. Another aspect of the present invention includes a superabsorpent polymer material placed in proximity to the anode gas diffusion backing to hold liquid methanol or liquid methanol solution without wetting the anode gas diffusion backing so that methanol vapor from the liquid methanol or liquid methanol-water solution is supplied to the membrane.

  14. Hematopoietic stem cells and the aging hematopoietic system.

    Science.gov (United States)

    Gazit, Roi; Weissman, Irving L; Rossi, Derrick J

    2008-10-01

    The etiology of the age-associated pathophysiological changes of the hematopoietic system including the onset of anemia, diminished adaptive immune competence, and myelogenous disease development are underwritten by the loss of normal homeostatic control. As tissue and organ homeostasis in adults is primarily mediated by the activity of stem and progenitor cells, it has been suggested that the imbalances accompanying aging of the hematopoietic system may stem from alterations in the prevalence and/or functional capacity of hematopoietic stem cells (HSCs) and progenitors. In this review, we examine evidence implicating a role for stem cells in the aging of the hematopoietic system, and focus on the mechanisms suggested to contribute to stem cell aging.

  15. Microculture system for studying monolayers of functional beta-cells.

    Science.gov (United States)

    Dobersen, M J; Scharff, J E; Notkins, A L

    1980-04-01

    A method is described for growing monolayers of newborn rat beta-cells in microculture trays. After disruption of the pancreas with collagenase, islets were isolated by Ficoll density gradient centrifugation, trypsinized to obtain individual cells, and plated in 96-well tissue culture trays. The cells were incubated for the first 3 days in growth medium containing 0.1 mM 3-isobutyl-1-methylxanthine to promote monolayer formation. The cultures could be maintained in a functional state, as defined by their responsiveness to known modulators of insulin secretion, for at least 2 weeks. As few as 1 X 10(3) islet cells/well gave results that were reproducible within +/- 10%. It is suggested that the microculture system for islet cells might prove to be a rapid and reproducible screening technique for studying drugs, viruses, or other agents that affect beta-cell function.

  16. A portable power system using PEM fuel cells

    Energy Technology Data Exchange (ETDEWEB)

    Long, E. [Ball Aerospace and Technologies Corp., Boulder, CO (United States)

    1997-12-31

    Ball has developed a proof-of-concept, small, lightweight, portable power system. The power system uses a proton exchange membrane (PEM) fuel cell stack, stored hydrogen, and atmospheric oxygen as the oxidant to generate electrical power. Electronics monitor the system performance to control cooling air and oxidant flow, and automatically do corrective measures to maintain performance. With the controller monitoring the system health, the system can operate in an ambient environment from 0 C to +50 C. The paper describes system testing, including load testing, thermal and humidity testing, vibration and shock testing, field testing, destructive testing of high-pressure gas tanks, and test results on the fuel cell power system, metal hydride hydrogen storage, high-pressure hydrogen gas storage, and chemical hydride hydrogen storage.

  17. Fuel quality issues in stationary fuel cell systems.

    Energy Technology Data Exchange (ETDEWEB)

    Papadias, D.; Ahmed, S.; Kumar, R. (Chemical Sciences and Engineering Division)

    2012-02-07

    Fuel cell systems are being deployed in stationary applications for the generation of electricity, heat, and hydrogen. These systems use a variety of fuel cell types, ranging from the low temperature polymer electrolyte fuel cell (PEFC) to the high temperature solid oxide fuel cell (SOFC). Depending on the application and location, these systems are being designed to operate on reformate or syngas produced from various fuels that include natural gas, biogas, coal gas, etc. All of these fuels contain species that can potentially damage the fuel cell anode or other unit operations and processes that precede the fuel cell stack. These detrimental effects include loss in performance or durability, and attenuating these effects requires additional components to reduce the impurity concentrations to tolerable levels, if not eliminate the impurity entirely. These impurity management components increase the complexity of the fuel cell system, and they add to the system's capital and operating costs (such as regeneration, replacement and disposal of spent material and maintenance). This project reviewed the public domain information available on the impurities encountered in stationary fuel cell systems, and the effects of the impurities on the fuel cells. A database has been set up that classifies the impurities, especially in renewable fuels, such as landfill gas and anaerobic digester gas. It documents the known deleterious effects on fuel cells, and the maximum allowable concentrations of select impurities suggested by manufacturers and researchers. The literature review helped to identify the impurity removal strategies that are available, and their effectiveness, capacity, and cost. A generic model of a stationary fuel-cell based power plant operating on digester and landfill gas has been developed; it includes a gas processing unit, followed by a fuel cell system. The model includes the key impurity removal steps to enable predictions of impurity breakthrough

  18. Image analysis driven single-cell analytics for systems microbiology.

    Science.gov (United States)

    Balomenos, Athanasios D; Tsakanikas, Panagiotis; Aspridou, Zafiro; Tampakaki, Anastasia P; Koutsoumanis, Konstantinos P; Manolakos, Elias S

    2017-04-04

    Time-lapse microscopy is an essential tool for capturing and correlating bacterial morphology and gene expression dynamics at single-cell resolution. However state-of-the-art computational methods are limited in terms of the complexity of cell movies that they can analyze and lack of automation. The proposed Bacterial image analysis driven Single Cell Analytics (BaSCA) computational pipeline addresses these limitations thus enabling high throughput systems microbiology. BaSCA can segment and track multiple bacterial colonies and single-cells, as they grow and divide over time (cell segmentation and lineage tree construction) to give rise to dense communities with thousands of interacting cells in the field of view. It combines advanced image processing and machine learning methods to deliver very accurate bacterial cell segmentation and tracking (F-measure over 95%) even when processing images of imperfect quality with several overcrowded colonies in the field of view. In addition, BaSCA extracts on the fly a plethora of single-cell properties, which get organized into a database summarizing the analysis of the cell movie. We present alternative ways to analyze and visually explore the spatiotemporal evolution of single-cell properties in order to understand trends and epigenetic effects across cell generations. The robustness of BaSCA is demonstrated across different imaging modalities and microscopy types. BaSCA can be used to analyze accurately and efficiently cell movies both at a high resolution (single-cell level) and at a large scale (communities with many dense colonies) as needed to shed light on e.g. how bacterial community effects and epigenetic information transfer play a role on important phenomena for human health, such as biofilm formation, persisters' emergence etc. Moreover, it enables studying the role of single-cell stochasticity without losing sight of community effects that may drive it.

  19. Automotive Fuel Processor Development and Demonstration with Fuel Cell Systems

    Energy Technology Data Exchange (ETDEWEB)

    Nuvera Fuel Cells

    2005-04-15

    The potential for fuel cell systems to improve energy efficiency and reduce emissions over conventional power systems has generated significant interest in fuel cell technologies. While fuel cells are being investigated for use in many applications such as stationary power generation and small portable devices, transportation applications present some unique challenges for fuel cell technology. Due to their lower operating temperature and non-brittle materials, most transportation work is focusing on fuel cells using proton exchange membrane (PEM) technology. Since PEM fuel cells are fueled by hydrogen, major obstacles to their widespread use are the lack of an available hydrogen fueling infrastructure and hydrogen's relatively low energy storage density, which leads to a much lower driving range than conventional vehicles. One potential solution to the hydrogen infrastructure and storage density issues is to convert a conventional fuel such as gasoline into hydrogen onboard the vehicle using a fuel processor. Figure 2 shows that gasoline stores roughly 7 times more energy per volume than pressurized hydrogen gas at 700 bar and 4 times more than liquid hydrogen. If integrated properly, the fuel processor/fuel cell system would also be more efficient than traditional engines and would give a fuel economy benefit while hydrogen storage and distribution issues are being investigated. Widespread implementation of fuel processor/fuel cell systems requires improvements in several aspects of the technology, including size, startup time, transient response time, and cost. In addition, the ability to operate on a number of hydrocarbon fuels that are available through the existing infrastructure is a key enabler for commercializing these systems. In this program, Nuvera Fuel Cells collaborated with the Department of Energy (DOE) to develop efficient, low-emission, multi-fuel processors for transportation applications. Nuvera's focus was on (1) developing fuel

  20. Development of bioengineering system for stem cell proliferation

    Science.gov (United States)

    Park, H. S.; Shah, R.; Shah, C.

    2016-08-01

    From last decades, intensive research in the field of stem cells proliferation had been promoted due to the unique property of stem cells to self-renew themselves into multiples and has potential to replicate into an organ or tissues and so it's highly demanding though challenging. Bioreactor, a mechanical device, works as a womb for stem cell proliferation by providing nutritious environment for the proper growth of stem cells. Various factors affecting stem cells growth are the bioreactor mechanism, feeding of continuous nutrients, healthy environment, etc., but it always remains a challenge for controlling biological parameters. The present paper unveils the design of mechanical device commonly known as bioreactor in tissues engineering and biotech field, use for proliferation of stem cells and imparts the proper growing condition for stem cells. This high functional bioreactor provides automation mixing of cell culture and stem cells. This design operates in conjunction with mechanism of reciprocating motion. Compare to commercial bioreactors, this proposed design is more convenient, easy to operate and less maintenance is required as bioreactor culture bag is made of polyethylene which is single use purpose. Development of this bioengineering system will be beneficial for better growth and expansion of stem cell

  1. B lymphocyte lineage cells and the respiratory system

    Science.gov (United States)

    Kato, Atsushi; Hulse, Kathryn E.; Tan, Bruce K.; Schleimer, Robert P.

    2013-01-01

    Adaptive humoral immune responses in the airways are mediated by B cells and plasma cells that express highly evolved and specific receptors and produce immunoglobulins of most isotypes. In some cases, such as autoimmune diseases or inflammatory diseases caused by excessive exposure to foreign antigens, these same immune cells can cause disease by virtue of overly vigorous responses. This review discusses the generation, differentiation, signaling, activation and recruitment pathways of B cells and plasma cells, with special emphasis on unique characteristics of subsets of these cells functioning within the respiratory system. The primary sensitization events that generate B cells responsible for effector responses throughout the airways usually occur in the upper airways, in tonsils and adenoid structures that make up Waldeyer’s Ring. Upon secondary exposure to antigen in the airways, antigen-processing dendritic cells migrate into secondary lymphoid organs such as lymph nodes that drain the upper and lower airways and further B cell expansion takes place at those sites. Antigen exposure in the upper or lower airways can also drive expansion of B lineage cells in the airway mucosal tissue and lead to the formation of inducible lymphoid follicles or aggregates that can mediate local immunity or disease. PMID:23540615

  2. Feedback dynamics and cell function: Why systems biology is called Systems Biology.

    Science.gov (United States)

    Wolkenhauer, Olaf; Mesarovic, Mihajlo

    2005-05-01

    A new paradigm, like Systems Biology, should challenge the way research has been conducted previously. This Opinion article aims to present Systems Biology, not as the application of engineering principles to biology but as a merger of systems- and control theory with molecular- and cell biology. In our view, the central dogma of Systems Biology is that it is system dynamics that gives rise to the functioning and function of cells. The concepts of feedback regulation and control of pathways and the coordination of cell function are emphasized as an important area of Systems Biology research. The hurdles and risks for this area are discussed from the perspective of dynamic pathway modelling. Most of all, the aim of this article is to promote mathematical modelling and simulation as a part of molecular- and cell biology. Systems Biology is a success if it is widely accepted that there is nothing more practical than a good theory.

  3. DRAGON, Reactor Cell Calculation System with Burnup

    International Nuclear Information System (INIS)

    2007-01-01

    1 - Description of program or function: DRAGON is a collection of models to simulate the neutronic behavior of a unit cell or a fuel assembly in a nuclear reactor. It includes all of the functions that characterize a lattice cell code, namely: interpolation of microscopic cross sections supplied by means of standard libraries; resonance self-shielding calculations in multidimensional geometries; multigroup and multidimensional neutron flux calculations which can take into account neutron leakage; transport-transport or transport-diffusion equivalence calculations as well as editing of condensed and homogenized nuclear properties for reactor calculations; and finally isotopic depletion calculations. The user must supply cross sections. DRAGON can access directly standard microscopic cross-section libraries in the following formats: DRAGON, MATXS (TRANSX-CTR), WIMSD4, WIMS-AECL, and APOLLO. It has the capability of exchanging macroscopic and microscopic cross-section libraries with a code such as PSR-0206/TRANSX-CTR or PSR-0317/TRANSX-2 by the use of the GOXS and ISOTXS format files. Macroscopic cross sections can also be read in DRAGON via the input data stream. 2 - Method of solution: DRAGON contains a multigroup iterator conceived to control a number of different algorithms for the solution of the neutron transport equation. Each of these algorithms is presented in the form of a one-group solution procedure where the contributions from other energy groups are included in a source term. The current version, DRAGON 9 71124 (Release 3.02), which was released in January 1998, contains three such algorithms. The JPM option solves the integral transport equation using the interface current method applied to homogeneous blocks; the SYBIL option solves the integral transport equation using the collision probability method for simple one-dimensional (1-D) or two-dimensional (2-D) geometries and the interface current method for 2-D Cartesian or hexagonal assemblies; and the

  4. FPGA based Control of a Production Cell System

    NARCIS (Netherlands)

    Groothuis, M.A.; van Zuijlen, Jasper J.P.; Broenink, Johannes F.

    Most motion control systems for mechatronic systems are implemented on digital computers. In this paper we present an FPGA based solution implemented on a low cost Xilinx Spartan III FPGA. A Production Cell setup with multiple parallel operating units is chosen as a test case. The embedded control

  5. Engineering systems for the generation of patterned co-cultures for controlling cell-cell interactions.

    Science.gov (United States)

    Kaji, Hirokazu; Camci-Unal, Gulden; Langer, Robert; Khademhosseini, Ali

    2011-03-01

    Inside the body, cells lie in direct contact or in close proximity to other cell types in a tightly controlled architecture that often regulates the resulting tissue function. Therefore, tissue engineering constructs that aim to reproduce the architecture and the geometry of tissues will benefit from methods of controlling cell-cell interactions with microscale resolution. We discuss the use of microfabrication technologies for generating patterned co-cultures. In addition, we categorize patterned co-culture systems by cell type and discuss the implications of regulating cell-cell interactions in the resulting biological function of the tissues. Patterned co-cultures are a useful tool for fabricating tissue engineered constructs and for studying cell-cell interactions in vitro, because they can be used to control the degree of homotypic and heterotypic cell-cell contact. In addition, this approach can be manipulated to elucidate important factors involved in cell-matrix interactions. Patterned co-culture strategies hold significant potential to develop biomimetic structures for tissue engineering. It is expected that they would create opportunities to develop artificial tissues in the future. This article is part of a Special Issue entitled Nanotechnologies - Emerging Applications in Biomedicine. 2010 Elsevier B.V. All rights reserved.

  6. Fuel cell system economics: comparing the costs of generating power with stationary and motor vehicle PEM fuel cell systems

    International Nuclear Information System (INIS)

    Lipman, Timothy E.; Edwards, Jennifer L.; Kammen, Daniel M.

    2004-01-01

    This investigation examines the economics of producing electricity from proton-exchange membrane (PEM) fuel cell systems under various conditions, including the possibility of using fuel cell vehicles (FCVs) to produce power when they are parked at office buildings and residences. The analysis shows that the economics of both stationary fuel cell and FCV-based power vary significantly with variations in key input variables such as the price of natural gas, electricity prices, fuel cell and reformer system costs, and fuel cell system durability levels. The 'central case' results show that stationary PEM fuel cell systems can supply electricity for offices and homes in California at a net savings when fuel cell system costs reach about $6000 for a 5 kW home system ($1200/kW) and $175,000 for a 250 kW commercial system ($700/kW) and assuming somewhat favorable natural gas costs of $6/GJ at residences and $4/GJ at commercial buildings. Grid-connected FCVs in commercial settings can also potentially supply electricity at competitive rates, in some cases producing significant annual benefits. Particularly attractive is the combination of net metering along with time-of-use electricity rates that allow power to be supplied to the utility grid at the avoided cost of central power plant generation. FCV-based power at individual residences does not appear to be as attractive, at least where FCV power can only be used directly or banked with the utility for net metering and not sold in greater quantity, due to the low load levels at these locations that provide a poor match to automotive fuel cell operation, higher natural gas prices than are available at commercial settings, and other factors

  7. Glial Cells: The Other Cells of the Nervous System-Astrocytes–Star ...

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 7; Issue 4. Glial Cells: The Other Cells of the Nervous System - Astrocytes – Star Performers in the Neural Tissue. Medha S Rajadhyaksha Daya Manghani. Series Article Volume 7 Issue 4 April 2002 pp 20-26 ...

  8. Glial Cells: The Other Cells of the Nervous System-Microglia–The ...

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 7; Issue 10. Glial Cells: The Other Cells of the Nervous System - Microglia – The Guardians of the CNS. Medha S Rajadhyaksha Daya Manghani. Series Article Volume 7 Issue 10 October 2002 pp 23-29 ...

  9. System level modeling and component level control of fuel cells

    Science.gov (United States)

    Xue, Xingjian

    This dissertation investigates the fuel cell systems and the related technologies in three aspects: (1) system-level dynamic modeling of both PEM fuel cell (PEMFC) and solid oxide fuel cell (SOFC); (2) condition monitoring scheme development of PEM fuel cell system using model-based statistical method; and (3) strategy and algorithm development of precision control with potential application in energy systems. The dissertation first presents a system level dynamic modeling strategy for PEM fuel cells. It is well known that water plays a critical role in PEM fuel cell operations. It makes the membrane function appropriately and improves the durability. The low temperature operating conditions, however, impose modeling difficulties in characterizing the liquid-vapor two phase change phenomenon, which becomes even more complex under dynamic operating conditions. This dissertation proposes an innovative method to characterize this phenomenon, and builds a comprehensive model for PEM fuel cell at the system level. The model features the complete characterization of multi-physics dynamic coupling effects with the inclusion of dynamic phase change. The model is validated using Ballard stack experimental result from open literature. The system behavior and the internal coupling effects are also investigated using this model under various operating conditions. Anode-supported tubular SOFC is also investigated in the dissertation. While the Nernst potential plays a central role in characterizing the electrochemical performance, the traditional Nernst equation may lead to incorrect analysis results under dynamic operating conditions due to the current reverse flow phenomenon. This dissertation presents a systematic study in this regard to incorporate a modified Nernst potential expression and the heat/mass transfer into the analysis. The model is used to investigate the limitations and optimal results of various operating conditions; it can also be utilized to perform the

  10. The thioredoxin system in breast cancer cell invasion and migration

    Directory of Open Access Journals (Sweden)

    Maneet Bhatia

    2016-08-01

    Full Text Available Metastasis is the most life threatening aspect of breast cancer. It is a multi-step process involving invasion and migration of primary tumor cells with a subsequent colonization of these cells at a secondary location. The aim of the present study was to investigate the role of thioredoxin (Trx1 in the invasion and migration of breast cancer cells and to assess the strength of the association between high levels of Trx1 and thioredoxin reductase (TrxR1 expression with breast cancer patient survival. Our results indicate that the expression of both Trx1 and TrxR1 are statistically significantly increased in breast cancer patient cells compared with paired normal breast tissue from the same patient. Over-expression of Trx1 in MDA-MB-231 breast cancer cell lines enhanced cell invasion in in vitro assays while expression of a redox inactive mutant form of Trx1 (designated 1SS or the antisense mRNA inhibited cell invasion. Addition of exogenous Trx1 also enhanced cell invasion, while addition of a specific monoclonal antibody that inhibits Trx1 redox function decreased cell invasion. Over-expression of intracellular Trx1 did not increase cell migration but expression of intracellular 1SS inhibited migration. Addition of exogenous Trx1 enhanced cell migration while 1SS had no effect. Treatment with auranofin inhibited TrxR activity, cell migration and clonogenic activity of MDA-MB-231 cells, while increasing reactive oxygen species (ROS levels. Analysis of 25 independent cohorts with 5910 patients showed that Trx1 and TrxR1 were both associated with a poor patient prognosis in terms of overall survival, distant metastasis free survival and disease free survival. Therefore, targeting the Trx system with auranofin or other specific inhibitors may provide improved breast cancer patient outcomes through inhibition of cancer invasion and migration.

  11. Solid Oxide Fuel Cell Hybrid System for Distributed Power Generation

    Energy Technology Data Exchange (ETDEWEB)

    David Deangelis; Rich Depuy; Debashis Dey; Georgia Karvountzi; Nguyen Minh; Max Peter; Faress Rahman; Pavel Sokolov; Deliang Yang

    2004-09-30

    This report summarizes the work performed by Hybrid Power Generation Systems, LLC (HPGS) during the April to October 2004 reporting period in Task 2.3 (SOFC Scaleup for Hybrid and Fuel Cell Systems) under Cooperative Agreement DE-FC26-01NT40779 for the U. S. Department of Energy, National Energy Technology Laboratory (DOE/NETL), entitled ''Solid Oxide Fuel Cell Hybrid System for Distributed Power Generation''. This study analyzes the performance and economics of power generation systems for central power generation application based on Solid Oxide Fuel Cell (SOFC) technology and fueled by natural gas. The main objective of this task is to develop credible scale up strategies for large solid oxide fuel cell-gas turbine systems. System concepts that integrate a SOFC with a gas turbine were developed and analyzed for plant sizes in excess of 20 MW. A 25 MW plant configuration was selected with projected system efficiency of over 65% and a factory cost of under $400/kW. The plant design is modular and can be scaled to both higher and lower plant power ratings. Technology gaps and required engineering development efforts were identified and evaluated.

  12. Particle dynamics and particle-cell interaction in microfluidic systems

    Science.gov (United States)

    Stamm, Matthew T.

    Particle-laden flow in a microchannel resulting in aggregation of microparticles was investigated to determine the dependence of the cluster growth rate on the following parameters: suspension void fraction, shear strain rate, and channel-height to particle-diameter ratio. The growth rate of an average cluster was found to increase linearly with suspension void fraction, and to obey a power-law relationships with shear strain rate as S 0.9 and channel-height to particle-diameter ratio as (h/d )--3.5. Ceramic liposomal nanoparticles and silica microparticles were functionalized with antibodies that act as targeting ligands. The bio-functionality and physical integrity of the cerasomes were characterized. Surface functionalization allows cerasomes to deliver drugs with selectivity and specificity that is not possible using standard liposomes. The functionalized particle-target cell binding process was characterized using BT-20 breast cancer cells. Two microfluidic systems were used; one with both species in suspension, the other with cells immobilized inside a microchannel and particle suspension as the mobile phase. Effects of incubation time, particle concentration, and shear strain rate on particle-cell binding were investigated. With both species in suspension, the particle-cell binding process was found to be reasonably well-described by a first-order model. Particle desorption and cellular loss of binding affinity in time were found to be negligible; cell-particle-cell interaction was identified as the limiting mechanism in particle-cell binding. Findings suggest that separation of a bound particle from a cell may be detrimental to cellular binding affinity. Cell-particle-cell interactions were prevented by immobilizing cells inside a microchannel. The initial stage of particle-cell binding was investigated and was again found to be reasonably well-described by a first-order model. For both systems, the time constant was found to be inversely proportional to

  13. The Pathology of T Cells in Systemic Lupus Erythematosus

    Directory of Open Access Journals (Sweden)

    Anselm Mak

    2014-01-01

    Full Text Available Systemic lupus erythematosus (SLE is characterized by the production of a wide array of autoantibodies. Thus, the condition was traditionally classified as a “B-cell disease”. Compelling evidence has however shown that without the assistance of the helper T lymphocytes, it is indeed difficult for the “helpless” B cells to become functional enough to trigger SLE-related inflammation. T cells have been recognized to be crucial in the pathogenicity of SLE through their capabilities to communicate with and offer enormous help to B cells for driving autoantibody production. Recently, a number of phenotypic and functional alterations which increase the propensity to trigger lupus-related inflammation have been identified in lupus T cells. Here, potential mechanisms involving alterations in T-cell receptor expressions, postreceptor downstream signalling, epigenetics, and oxidative stress which favour activation of lupus T cells will be discussed. Additionally, how regulatory CD4+, CD8+, and γδ T cells tune down lupus-related inflammation will be highlighted. Lastly, while currently available outcomes of clinical trials evaluating therapeutic agents which manipulate the T cells such as calcineurin inhibitors indicate that they are at least as efficacious and safe as conventional immunosuppressants in treating lupus glomerulonephritis, larger clinical trials are undoubtedly required to validate these as-yet favourable findings.

  14. Fuel Cell System for Transportation -- 2005 Cost Estimate

    Energy Technology Data Exchange (ETDEWEB)

    Wheeler, D.

    2006-10-01

    Independent review report of the methodology used by TIAX to estimate the cost of producing PEM fuel cells using 2005 cell stack technology. The U.S. Department of Energy (DOE) Hydrogen, Fuel Cells and Infrastructure Technologies Program Manager asked the National Renewable Energy Laboratory (NREL) to commission an independent review of the 2005 TIAX cost analysis for fuel cell production. The NREL Systems Integrator is responsible for conducting independent reviews of progress toward meeting the DOE Hydrogen Program (the Program) technical targets. An important technical target of the Program is the proton exchange membrane (PEM) fuel cell cost in terms of dollars per kilowatt ($/kW). The Program's Multi-Year Program Research, Development, and Demonstration Plan established $125/kW as the 2005 technical target. Over the last several years, the Program has contracted with TIAX, LLC (TIAX) to produce estimates of the high volume cost of PEM fuel cell production for transportation use. Since no manufacturer is yet producing PEM fuel cells in the quantities needed for an initial hydrogen-based transportation economy, these estimates are necessary for DOE to gauge progress toward meeting its targets. For a PEM fuel cell system configuration developed by Argonne National Laboratory, TIAX estimated the total cost to be $108/kW, based on assumptions of 500,000 units per year produced with 2005 cell stack technology, vertical integration of cell stack manufacturing, and balance-of-plant (BOP) components purchased from a supplier network. Furthermore, TIAX conducted a Monte Carlo analysis by varying ten key parameters over a wide range of values and estimated with 98% certainty that the mean PEM fuel cell system cost would be below DOE's 2005 target of $125/kW. NREL commissioned DJW TECHNOLOGY, LLC to form an Independent Review Team (the Team) of industry fuel cell experts and to evaluate the cost estimation process and the results reported by TIAX. The results of

  15. Role of hydrogen in future North European power system in 2060

    DEFF Research Database (Denmark)

    Meibom, Peter; Karlsson, Kenneth Bernard

    2010-01-01

    the future success of fuel cell technologies have been investigated as well as different electricity and heat demand assumptions. The variability of wind power production was handled by varying the hydropower production and the production on CHP plants using biomass, by power transmission, by varying...... the heat production in heat pumps and electric heat boilers, and by varying the production of hydrogen in electrolysis plants in combination with hydrogen storage. Investment in hydrogen storage capacity corresponded to 1.2% of annual wind power production in the scenarios without a hydrogen demand from......The Balmorel model has been used to calculate the economic optimal energy system configuration for the Scandinavian countries and Germany in 2060 assuming a nearly 100% coverage of the energy demands in the power, heat and transport sector with renewable energy sources. Different assumptions about...

  16. Distributed generation system using wind/photovoltaic/fuel cell

    Science.gov (United States)

    Buasri, Panhathai

    This dissertation investigates the performance and the operation of a distributed generation (DG) power system using wind/photovoltaic/fuel cell (W/PV/FC). The power system consists of a 2500 W photovoltaic array subsystem, a 500 W proton exchange membrane fuel cell (PEMFC) stack subsystem, 300 W wind turbine, 500 W wind turbine, and 1500 W wind energy conversion subsystems. To extract maximum power from the PV, a maximum power point tracker was designed and fabricated. A 4 kW single phase inverter was used to convert the DC voltage to AC voltage; also a 44 kWh battery bank was used to store energy and prevent fluctuation of the power output of the DG system. To connect the fuel cell to the batteries, a DC/DC controller was designed and fabricated. To monitor and study the performance of the DG system under variable conditions, a data acquisition system was designed and installed. The fuel cell subsystem performance was evaluated under standalone operation using a variable resistance and under interactive mode, connected to the batteries. The manufacturing data and the experimental data were used to develop an electrical circuit model to the fuel cell. Furthermore, harmonic analysis of the DG system was investigated. For an inverter, the AC voltage delivered to the grid changed depending on the time, load, and electronic equipment that was connected. The quality of the DG system was evaluated by investigating the harmonics generated by the power electronics converters. Finally, each individual subsystem of the DG system was modeled using the neuro-fuzzy approach. The model was used to predict the performance of the DG system under variable conditions, such as passing clouds and wind gust conditions. The steady-state behaviors of the model were validated by the experimental results under different operating conditions.

  17. System and method for detecting cells or components thereof

    Science.gov (United States)

    Porter, Marc D [Ames, IA; Lipert, Robert J [Ames, IA; Doyle, Robert T [Ames, IA; Grubisha, Desiree S [Corona, CA; Rahman, Salma [Ames, IA

    2009-01-06

    A system and method for detecting a detectably labeled cell or component thereof in a sample comprising one or more cells or components thereof, at least one cell or component thereof of which is detectably labeled with at least two detectable labels. In one embodiment, the method comprises: (i) introducing the sample into one or more flow cells of a flow cytometer, (ii) irradiating the sample with one or more light sources that are absorbed by the at least two detectable labels, the absorption of which is to be detected, and (iii) detecting simultaneously the absorption of light by the at least two detectable labels on the detectably labeled cell or component thereof with an array of photomultiplier tubes, which are operably linked to two or more filters that selectively transmit detectable emissions from the at least two detectable labels.

  18. T-cell-directed therapies in systemic lupus erythematosus.

    Science.gov (United States)

    Nandkumar, P; Furie, R

    2016-09-01

    Drug development for the treatment of systemic lupus erythematosus (SLE) has largely focused on B-cell therapies. A greater understanding of the immunopathogenesis of SLE coupled with advanced bioengineering has allowed for clinical trials centered on other targets for SLE therapy. The authors discuss the benefits and shortcomings of focusing on T-cell-directed therapies in SLE and lupus nephritis clinical trials. © The Author(s) 2016.

  19. Table 2.2. Cell voltages with nonaqueous electrolyte systems

    Science.gov (United States)

    Holze, R.

    This document is part of Volume 9 `Electrochemistry', Subvolume A, of Landolt-Börnstein - Group IV `Physical Chemistry'. The document lists the normal voltages of cells in nonaqueous electrolyte systems. The cells are composed of the following materials: silver (Ag), barium (Ba), calcium (Ca), cadmium (Cd), cerium (Ce), copper (Cu), hydrogen (H), mercury (Hg), potassium (K), lanthanum (La), lithium (Li), magnesium (Mg), natrium (Na), lead (Pb), platinum (Pt), rubidium (Rb), thallium (Tl), zinc (Zn). The compositions of the cells are given along with, where available, the temperatures of measurements of the voltages.

  20. Speech recognition systems on the Cell Broadband Engine

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Y; Jones, H; Vaidya, S; Perrone, M; Tydlitat, B; Nanda, A

    2007-04-20

    In this paper we describe our design, implementation, and first results of a prototype connected-phoneme-based speech recognition system on the Cell Broadband Engine{trademark} (Cell/B.E.). Automatic speech recognition decodes speech samples into plain text (other representations are possible) and must process samples at real-time rates. Fortunately, the computational tasks involved in this pipeline are highly data-parallel and can receive significant hardware acceleration from vector-streaming architectures such as the Cell/B.E. Identifying and exploiting these parallelism opportunities is challenging, but also critical to improving system performance. We observed, from our initial performance timings, that a single Cell/B.E. processor can recognize speech from thousands of simultaneous voice channels in real time--a channel density that is orders-of-magnitude greater than the capacity of existing software speech recognizers based on CPUs (central processing units). This result emphasizes the potential for Cell/B.E.-based speech recognition and will likely lead to the future development of production speech systems using Cell/B.E. clusters.

  1. Tensegrity I. Cell structure and hierarchical systems biology

    Science.gov (United States)

    Ingber, Donald E.

    2003-01-01

    In 1993, a Commentary in this journal described how a simple mechanical model of cell structure based on tensegrity architecture can help to explain how cell shape, movement and cytoskeletal mechanics are controlled, as well as how cells sense and respond to mechanical forces (J. Cell Sci. 104, 613-627). The cellular tensegrity model can now be revisited and placed in context of new advances in our understanding of cell structure, biological networks and mechanoregulation that have been made over the past decade. Recent work provides strong evidence to support the use of tensegrity by cells, and mathematical formulations of the model predict many aspects of cell behavior. In addition, development of the tensegrity theory and its translation into mathematical terms are beginning to allow us to define the relationship between mechanics and biochemistry at the molecular level and to attack the larger problem of biological complexity. Part I of this two-part article covers the evidence for cellular tensegrity at the molecular level and describes how this building system may provide a structural basis for the hierarchical organization of living systems--from molecule to organism. Part II, which focuses on how these structural networks influence information processing networks, appears in the next issue.

  2. Synthesis of Evolving Cells for Reconfigurable Manufacturing Systems

    Science.gov (United States)

    Padayachee, J.; Bright, G.

    2014-07-01

    The concept of Reconfigurable Manufacturing Systems (RMSs) was formulated due to the global necessity for production systems that are able to economically evolve according to changes in markets and products. Technologies and design methods are under development to enable RMSs to exhibit transformable system layouts, reconfigurable processes, cells and machines. Existing factory design methods and software have not yet advanced to include reconfigurable manufacturing concepts. This paper presents the underlying group technology framework for the design of manufacturing cells that are able to evolve according to a changing product mix by mechanisms of reconfiguration. The framework is based on a Norton- Bass forecast and time variant BOM models. An adaptation of legacy group technology methods is presented for the synthesis of evolving cells and two optimization problems are presented within this context.

  3. Jet Fuel Based High Pressure Solid Oxide Fuel Cell System

    Science.gov (United States)

    Gummalla, Mallika (Inventor); Yamanis, Jean (Inventor); Olsommer, Benoit (Inventor); Dardas, Zissis (Inventor); Bayt, Robert (Inventor); Srinivasan, Hari (Inventor); Dasgupta, Arindam (Inventor); Hardin, Larry (Inventor)

    2015-01-01

    A power system for an aircraft includes a solid oxide fuel cell system which generates electric power for the aircraft and an exhaust stream; and a heat exchanger for transferring heat from the exhaust stream of the solid oxide fuel cell to a heat requiring system or component of the aircraft. The heat can be transferred to fuel for the primary engine of the aircraft. Further, the same fuel can be used to power both the primary engine and the SOFC. A heat exchanger is positioned to cool reformate before feeding to the fuel cell. SOFC exhaust is treated and used as inerting gas. Finally, oxidant to the SOFC can be obtained from the aircraft cabin, or exterior, or both.

  4. Control of Cell Fate in the Circulatory and Ventilatory Systems

    CERN Document Server

    Thiriet, Marc

    2012-01-01

    The volumes in this authoritative series present a multidisciplinary approach to modeling and simulation of flows in the cardiovascular and ventilatory systems, especially multiscale modeling and coupled simulations. The cardiovascular and respiratory systems are tightly coupled, as their primary function is to supply oxygen to and remove carbon dioxide from the body's cells. Because physiological conduits have deformable and reactive walls, macroscopic flow behavior and prediction must be coupled to nano- and microscopic events in a corrector scheme of regulated mechanisms. Therefore, investigation of flows of blood and air in physiological conduits requires an understanding of the biology, chemistry, and physics of these systems together with the mathematical tools to describe their functioning. Volumes 1 and 2 are devoted to cell organization and fate, as well as activities that are autoregulated and/or controlled by the cell environment. Volume 1 examined cellular features that allow adaptation to env...

  5. Treatment of systemic sclerosis: potential role for stem cell transplantation

    Directory of Open Access Journals (Sweden)

    Wen Xiong

    2009-11-01

    Full Text Available Wen Xiong, Chris T DerkDivision of Rheumatology, Thomas Jefferson University, Philadelphia, PA, 19107, USAAbstract: Hematopoietic stem cell transplantation may “reset” the immune reconstitution and induce self tolerance of autoreactive lymphocytes, and has been explored in the treatments for systemic sclerosis. Phase I/II trials have shown a satisfactory risk benefit ratio. The true benefit will be identified by two ongoing prospective, randomized phase III trials. Multipotent mesenchymal stromal cells (MSCs possess antiproliferative, anti-inflammatory, and immunosuppressive properties. The use of MSCs has showed successful responses in patients with severe steroid-resistant acute graft versus host disease in phase II trials, and may be a potentially promising option for patients with systemic sclerosis.Keywords: scleroderma, systemic sclerosis, treatment, stem cells, transplant

  6. FFTF/IEM cell fuel pin weighing system

    International Nuclear Information System (INIS)

    Gibbons, P.W.

    1987-01-01

    The Interim Examination and Maintenance (IEM) cell in the Fast Flux Test Facility (FFTF) is used for remote disassembly of irradiated fuel and materials experiments. For those fuel experiments where the FFTF tag-gas detection system has indicated a fuel pin cladding breach, a weighing system is used in identifying that fuel pin with a reduced weight due to the escape of gaseous and volatile fission products. A fuel pin weighing machine, originally purchased for use in the Fuels and Materials Examination Facility (FMEF), was the basis for the IEM cell system. Design modifications to the original equipment were centered around adapting the machine to the differences between the two facilities and correcting deficiencies discovered during functional testing in the IEM cell mock-up

  7. System-level modeling and simulation of the cell culture microfluidic biochip ProCell

    DEFF Research Database (Denmark)

    Minhass, Wajid Hassan; Pop, Paul; Madsen, Jan

    2010-01-01

    Microfluidic biochips offer a promising alternative to a conventional biochemical laboratory. There are two technologies for the microfluidic biochips: droplet-based and flow-based. In this paper we are interested in flow-based microfluidic biochips, where the liquid flows continuously through pre......-defined micro-channels using valves and pumps. We present an approach to the system-level modeling and simulation of a cell culture microfluidic biochip called ProCell, Programmable Cell Culture Chip. ProCell contains a cell culture chamber, which is envisioned to run 256 simultaneous experiments (viewed...... and a comprehensive fault model that captures permanent faults occurring during chip operation. Using the proposed modeling and simulation framework, we perform an architectural level evaluation of two cell culture chamber implementations. A qualitative success metric is also proposed to evaluate chip performance...

  8. Application of Predictive Control in District Heating Systems

    DEFF Research Database (Denmark)

    Palsson, Olafur Petur; Madsen, Henrik; Søgaard, Henning Tangen

    1993-01-01

    In district heating systems, and in particular if the heat production cakes place at a combined heat and power (CHP) plant, a reasonable control strategy is to keep the supply temperature from the district heating plant as low as possible. However, the control is subject to some restrictions...

  9. Systems biology. Conditional density-based analysis of T cell signaling in single-cell data.

    Science.gov (United States)

    Krishnaswamy, Smita; Spitzer, Matthew H; Mingueneau, Michael; Bendall, Sean C; Litvin, Oren; Stone, Erica; Pe'er, Dana; Nolan, Garry P

    2014-11-28

    Cellular circuits sense the environment, process signals, and compute decisions using networks of interacting proteins. To model such a system, the abundance of each activated protein species can be described as a stochastic function of the abundance of other proteins. High-dimensional single-cell technologies, such as mass cytometry, offer an opportunity to characterize signaling circuit-wide. However, the challenge of developing and applying computational approaches to interpret such complex data remains. Here, we developed computational methods, based on established statistical concepts, to characterize signaling network relationships by quantifying the strengths of network edges and deriving signaling response functions. In comparing signaling between naïve and antigen-exposed CD4(+) T lymphocytes, we find that although these two cell subtypes had similarly wired networks, naïve cells transmitted more information along a key signaling cascade than did antigen-exposed cells. We validated our characterization on mice lacking the extracellular-regulated mitogen-activated protein kinase (MAPK) ERK2, which showed stronger influence of pERK on pS6 (phosphorylated-ribosomal protein S6), in naïve cells as compared with antigen-exposed cells, as predicted. We demonstrate that by using cell-to-cell variation inherent in single-cell data, we can derive response functions underlying molecular circuits and drive the understanding of how cells process signals. Copyright © 2014, American Association for the Advancement of Science.

  10. Integrated Energy Systems (IES) for Buildings: A Market Assessment

    Energy Technology Data Exchange (ETDEWEB)

    LeMar, P.

    2002-10-29

    Integrated Energy Systems (IES) combine on-site power or distributed generation technologies with thermally activated technologies to provide cooling, heating, humidity control, energy storage and/or other process functions using thermal energy normally wasted in the production of electricity/power. IES produce electricity and byproduct thermal energy onsite, with the potential of converting 80 percent or more of the fuel into useable energy. IES have the potential to offer the nation the benefits of unprecedented energy efficiency gains, consumer choice and energy security. It may also dramatically reduce industrial and commercial building sector carbon and air pollutant emissions and increase source energy efficiency. Applications of distributed energy and Combined heat and power (CHP) in ''Commercial and Institutional Buildings'' have, however, been historically limited due to insufficient use of byproduct thermal energy, particularly during summer months when heating is at a minimum. In recent years, custom engineered systems have evolved incorporating potentially high-value services from Thermally Activated Technologies (TAT) like cooling and humidity control. Such TAT equipment can be integrated into a CHP system to utilize the byproduct heat output effectively to provide absorption cooling or desiccant humidity control for the building during these summer months. IES can therefore expand the potential thermal energy services and thereby extend the conventional CHP market into building sector applications that could not be economically served by CHP alone. Now more than ever, these combined cooling, heating and humidity control systems (IES) can potentially decrease carbon and air pollutant emissions, while improving source energy efficiency in the buildings sector. Even with these improvements over conventional CHP systems, IES face significant technological and economic hurdles. Of crucial importance to the success of IES is the ability

  11. Guide to Combined Heat and Power Systems for Boiler Owners and Operators

    Energy Technology Data Exchange (ETDEWEB)

    Oland, CB

    2004-08-19

    Combined heat and power (CHP) or cogeneration is the sequential production of two forms of useful energy from a single fuel source. In most CHP applications, chemical energy in fuel is converted to both mechanical and thermal energy. The mechanical energy is generally used to generate electricity, while the thermal energy or heat is used to produce steam, hot water, or hot air. Depending on the application, CHP is referred to by various names including Building Cooling, Heating, and Power (BCHP); Cooling, Heating, and Power for Buildings (CHPB); Combined Cooling, Heating, and Power (CCHP); Integrated Energy Systems (IES), or Distributed Energy Resources (DER). The principal technical advantage of a CHP system is its ability to extract more useful energy from fuel compared to traditional energy systems such as conventional power plants that only generate electricity and industrial boiler systems that only produce steam or hot water for process applications. By using fuel energy for both power and heat production, CHP systems can be very energy efficient and have the potential to produce electricity below the price charged by the local power provider. Another important incentive for applying cogeneration technology is to reduce or eliminate dependency on the electrical grid. For some industrial processes, the consequences of losing power for even a short period of time are unacceptable. The primary objective of the guide is to present information needed to evaluate the viability of cogeneration for new or existing industrial, commercial, and institutional (ICI) boiler installations and to make informed CHP equipment selection decisions. Information presented is meant to help boiler owners and operators understand the potential benefits derived from implementing a CHP project and recognize opportunities for successful application of cogeneration technology. Topics covered in the guide follow: (1) an overview of cogeneration technology with discussions about benefits

  12. Quinolone signaling in the cell-to-cell communication system of Pseudomonas aeruginosa

    Science.gov (United States)

    Pesci, Everett C.; Milbank, Jared B. J.; Pearson, James P.; McKnight, Susan; Kende, Andrew S.; Greenberg, E. Peter; Iglewski, Barbara H.

    1999-01-01

    Numerous species of bacteria use an elegant regulatory mechanism known as quorum sensing to control the expression of specific genes in a cell-density dependent manner. In Gram-negative bacteria, quorum sensing systems function through a cell-to-cell signal molecule (autoinducer) that consists of a homoserine lactone with a fatty acid side chain. Such is the case in the opportunistic human pathogen Pseudomonas aeruginosa, which contains two quorum sensing systems (las and rhl) that operate via the autoinducers, N-(3-oxododecanoyl)-l-homoserine lactone and N-butyryl-l-homoserine lactone. The study of these signal molecules has shown that they bind to and activate transcriptional activator proteins that specifically induce numerous P. aeruginosa virulence genes. We report here that P. aeruginosa produces another signal molecule, 2-heptyl-3-hydroxy-4-quinolone, which has been designated as the Pseudomonas quinolone signal. It was found that this unique cell-to-cell signal controlled the expression of lasB, which encodes for the major virulence factor, LasB elastase. We also show that the synthesis and bioactivity of Pseudomonas quinolone signal were mediated by the P. aeruginosa las and rhl quorum sensing systems, respectively. The demonstration that 2-heptyl-3-hydroxy-4-quinolone can function as an intercellular signal sheds light on the role of secondary metabolites and shows that P. aeruginosa cell-to-cell signaling is not restricted to acyl-homoserine lactones. PMID:10500159

  13. Fuel cell technology in Switzerland; Die Brennstoffzellen-Technologie in der Schweiz

    Energy Technology Data Exchange (ETDEWEB)

    Nieba, L.; Tauer, A.

    2001-07-01

    This is a short report assessing the present status of fuel cell technology development in Switzerland. In a first section the basic fuel cell variants are described, together with their potential uses according to their power and operating temperature ranges. The authors then highlight the expected market segments to be covered by Swiss fuel cells. In the mid term (10 years) they mainly see opportunities for combined heat and power (CHP) generation in residential buildings in the 1-10 kW power range by means of solid oxide fuel cells, for CHP generation in the 200 kW power range by means of phosphoric acid fuel cells as well as for devices replacing generators and motors in the 1 kW power range. In the longer run, many more opportunities may appear for fuel cells. Technology transfer from research and education institutes to industry has begun and should further be promoted.

  14. Innate lymphoid cells and natural killer T cells in the gastrointestinal tract immune system

    Directory of Open Access Journals (Sweden)

    Enrique Montalvillo

    2014-05-01

    Full Text Available The gastrointestinal tract is equipped with a highly specialized intrinsic immune system. However, the intestine is exposed to a high antigenic burden that requires a fast, nonspecific response -so-called innate immunity- to maintain homeostasis and protect the body from incoming pathogens. In the last decade multiple studies helped to unravel the particular developmental requirements and specific functions of the cells that play a role in innate immunity. In this review we shall focus on innate lymphoid cells, a newly discovered, heterogeneous set of cells that derive from an Id2-dependent lymphoid progenitor cell population. These cells have been categorized on the basis of the pattern of cytokines that they secrete, and the transcription factors that regulate their development and functions. Innate lymphoid cells play a role in the early response to pathogens, the anatomical contention of the commensal flora, and the maintenance of epithelial integrity. Amongst the various innate lymphoid cells we shall lay emphasis on a subpopulation with several peculiarities, namely that of natural killer T cells, a subset of T lymphocytes that express both T-cell and NK-cell receptors. The most numerous fraction of the NKT population are the so-called invariant NKT or iNKT cells. These iNKT cells have an invariant TCR and recognize the glycolipidic structures presented by the CD1d molecule, a homolog of class-I MHC molecules. Following activation they rapidly acquire cytotoxic activity and secrete both Th1 and Th2 cytokines, including IL-17. While their specific role is not yet established, iNKT cells take part in a great variety of intestinal immune responses ranging from oral tolerance to involvement in a number of gastrointestinal conditions.

  15. Modelling and control synthesis of a micro-combined heat and power interface for a concentrating solar power system in off-grid rural power applications

    Science.gov (United States)

    Prinsloo, Gerro; Dobson, Robert; Brent, Alan; Mammoli, Andrea

    2016-05-01

    Concentrating solar power co-generation systems have been identified as potential stand-alone solar energy supply solutions in remote rural energy applications. This study describes the modelling and synthesis of a combined heat and power Stirling CSP system in order to evaluate its potential performance in small off-grid rural village applications in Africa. This Stirling micro-Combined Heat and Power (micro-CHP) system has a 1 kW electric capacity, with 3 kW of thermal generation capacity which is produced as waste heat recovered from the solar power generation process. As part of the development of an intelligent microgrid control and distribution solution, the Trinum micro-CHP system and other co-generation systems are systematically being modelled on the TRNSYS simulation platform. This paper describes the modelling and simulation of the Trinum micro-CHP configuration on TRNSYS as part of the process to develop the control automation solution for the smart rural microgrid in which the Trinum will serve as a solar powerpack. The results present simulated performance outputs for the Trinum micro-CHP system for a number of remote rural locations in Africa computed from real-time TRNSYS solar irradiation and weather data (yearly, monthly, daily) for the relevant locations. The focus of this paper is on the parametric modelling of the Trinum Stirling micro-CHP system, with specific reference to this system as a TRNSYS functional block in the microgrid simulation. The model is used to forecast the solar energy harvesting potential of the Trinum micro-CHP unit at a number of remote rural sites in Africa.

  16. System for controlling the operating temperature of a fuel cell

    Science.gov (United States)

    Fabis, Thomas R.; Makiel, Joseph M.; Veyo, Stephen E.

    2006-06-06

    A method and system are provided for improved control of the operating temperature of a fuel cell (32) utilizing an improved temperature control system (30) that varies the flow rate of inlet air entering the fuel cell (32) in response to changes in the operating temperature of the fuel cell (32). Consistent with the invention an improved temperature control system (30) is provided that includes a controller (37) that receives an indication of the temperature of the inlet air from a temperature sensor (39) and varies the heat output by at least one heat source (34, 36) to maintain the temperature of the inlet air at a set-point T.sub.inset. The controller (37) also receives an indication of the operating temperature of the fuel cell (32) and varies the flow output by an adjustable air mover (33), within a predetermined range around a set-point F.sub.set, in order to maintain the operating temperature of the fuel cell (32) at a set-point T.sub.opset.

  17. A cell strain system for small homogeneous strain applications.

    Science.gov (United States)

    Bottlang, M; Simnacher, M; Schmitt, H; Brand, R A; Claes, L

    1997-11-01

    A cell culture system has been developed that enables application of well characterized, homogeneously distributed cyclic strains to monolayer cell cultures. Optically clear silicone culture dishes atop Plexiglas base plates are deformed by four-point bending of flexible silicone culture wells driven in user specified strain cycle patterns using computer controlled electromagnetic linear actuators. Cyclic mechano-transduction can be induced in amplitudes of 0 to 3000 mustrain, in frequencies of 0 to 30 Hz and in any specified strain cycle pattern. The cell culture system, which contains six simultaneously driven culture wells, has been mechanically characterized by holographic interferometry, laser displacement sensor recordings of the dish surfaces, strain gauge monitoring of the base plates, and finite element modeling of the dishes on the base plates. The standard deviation of the strain amplitudes among the six simultaneously stimulated culture wells is less than 5%. The cell culture system allows accurate generation of small magnitudes of well characterized, homogeneous strain, easy handling of the culture wells, flexible setting of cyclic strain pattern parameters, simultaneous stimulation of 6 culture wells, and light microscopic observation of the cell cultures.

  18. Modeling of Pem Fuel Cell Systems Including Controls and Reforming Effects for Hybrid Automotive Applications

    National Research Council Canada - National Science Library

    Boettner, Daisie

    2001-01-01

    .... This study develops models for a stand-alone Proton Exchange Membrane (PEM) fuel cell stack, a direct-hydrogen fuel cell system including auxiliaries, and a methanol reforming fuel cell system for integration into a vehicle performance simulator...

  19. Apoptosis and systemic autoimmunity: the dendritic cell connection

    Directory of Open Access Journals (Sweden)

    AA Manfredi

    2009-12-01

    Full Text Available Much effort has been devoted in recent years to the events linking recognition and disposal of apoptotic cells to sustained immunity towards the antigens they contain. Programmed death via apoptosis indeed provides most of the raw material the immune system exploits to establish self tolerance, i.e. to learn how to distinguish between self constituents and foreign antigens, belonging to invading pathogens. In parallel, events occurring during cell death may enable a restricted array of molecules endowed with diverse structure, function and intracellular distribution to satisfy the requirement to evoke and maintain autoimmune responses. Dendritic cells (DCs, the most potent antigen presenting cells, appear to play a crucial role. Here we will discuss some of the constrains regulating the access of dying cells’ antigens to DCs, as well as censorship mechanisms that prevent their maturation and the full explication of their antigen presenting function.

  20. Economic competitiveness of fuel cell onsite integrated energy systems

    Science.gov (United States)

    Bollenbacher, G.

    1983-01-01

    The economic competitiveness of fuel cell onsite integrated energy systems (OS/IES) in residential and commercial buildings is examined. The analysis is carried out for three different buildings with each building assumed to be at three geographic locations spanning a range of climatic conditions. Numerous design options and operating strategies are evaluated and two economic criteria are used to measure economic performance. In general the results show that fuel cell OS/IES's are competitive in most regions of the country if the OS/IES is properly designed. The preferred design is grid connected, makes effective use of the fuel cell's thermal output, and has a fuel cell powerplant sized for the building's base electrical load.

  1. Lithium-thionyl chloride cell system safety hazard analysis

    Science.gov (United States)

    Dampier, F. W.

    1985-03-01

    This system safety analysis for the lithium thionyl chloride cell is a critical review of the technical literature pertaining to cell safety and draws conclusions and makes recommendations based on this data. The thermodynamics and kinetics of the electrochemical reactions occurring during discharge are discussed with particular attention given to unstable SOCl2 reduction intermediates. Potentially hazardous reactions between the various cell components and discharge products or impurities that could occur during electrical or thermal abuse are described and the most hazardous conditions and reactions identified. Design factors influencing the safety of Li/SOCl2 cells, shipping and disposal methods and the toxicity of Li/SOCl2 battery components are additional safety issues that are also addressed.

  2. Expression and function of the endocannabinoid system in glial cells.

    Science.gov (United States)

    Massi, Paola; Valenti, Marta; Bolognini, Daniele; Parolaro, Daniela

    2008-01-01

    In the last few years the role and significance of the glia in CNS function and pathology have been drastically reassessed. Glial cells physiology appears very different in healthy versus pathological brain and the recent identification of cannabinoid receptors and their endogenous ligands in glia has triggered a number of studies exploring the role of (endo)cannabinoid system in glia functionality and disease. (Endo)cannabinoids exert their effects in these cells directly affecting some important peculiar functions of the glia and actively promoting biochemical signals ending in a pro-survival fate for these cells. By contrast, (endo)cannabinoids induce a selective death in glia-derived tumor cells. Of special physiological and therapeutic relevance is the reported ability of glial cells during neuropathological conditions to release an increased amount of endocannabinoids and to overexpress cannabinoid receptors. This evidence has suggested that the endocannabinoids production by glial cells may constitute an endogenous defense mechanism preventing the propagation of neuroinflammation and cell damage. The present paper will review the evidence supporting the regulatory role of (endo)cannabinoids in glia function, holding in consideration their therapeutic potential as neuroprotective and/or anticancer agents.

  3. Systems modelling and the development of coherent cell biological knowledge

    NARCIS (Netherlands)

    Verhoeff, R.; Waarlo, A.J.; Boersma, K.T.

    2008-01-01

    This article reports on educational design research concerning a learning and teaching strategy for cell biology in upper-secondary education introducing systems modelling as a key competence. The strategy consists of four modelling phases in which students subsequently develop models of freeliving

  4. Modeling fuel cells in integrated multi-energy systems

    NARCIS (Netherlands)

    Gabriellissx, Paolo; Gazzani, Matteo; Mazzotti, Marco

    2017-01-01

    This contribution investigates how different technology modeling methodologies affect the design of decentralized multi-energy systems, especially when fuel cell and energy storage are considered. First, thermoelectric models based on a first-principle approach are implemented to determine the

  5. Systems biology: From the cell to the brain

    Indian Academy of Sciences (India)

    Systems biology: From the cell to the brain. SITABHRA SINHA. 1,∗. , T JESAN. 2 and NIVEDITA CHATTERJEE. 3. 1. The Institute of Mathematical Sciences, CIT Campus, Taramani, Chennai 600 113, India. 2. Health Physics Division, Bhabha Atomic Research Centre, Kalpakkam 603 201, India. 3. Vision Research ...

  6. Glycoengineering in CHO cells: Advances in systems biology

    DEFF Research Database (Denmark)

    Tejwani, Vijay; Andersen, Mikael Rørdam; Nam, Jong Hyun

    2018-01-01

    are not well understood. A systems biology approach combining different technologies is needed for complete understanding of the molecular processes accounting for this variability and to open up new venues in cell line development. In this review, we describe several advances in genetic manipulation, modeling...

  7. Control board and utility system for cell complex

    International Nuclear Information System (INIS)

    Almeida, G.L. de; Silva, A.C.; Souza, A.S.F. de; Souza, M.L.M. de; Rautenberg, F.A.

    1986-01-01

    To attend necessities of hot cells operation and process control for isotope production in IEN cyclotron (Brazilian-CNEN) a utility system, such as, electricity, water, vacuum, air, and gas, and control board was constructed, which advantages are presented. (M.C.K.)

  8. Advanced energy analysis of high temperature fuel cell systems

    NARCIS (Netherlands)

    De Groot, A.

    2004-01-01

    In this thesis the performance of high temperature fuel cell systems is studied using a new method of exergy analysis. The thesis consists of three parts: ⢠In the first part a new analysis method is developed, which not only considers the total exergy losses in a unit operation, but which

  9. Establishment of sorghum cell suspension culture system for ...

    African Journals Online (AJOL)

    Total soluble proteins (TSP) and culture filtrate (CF) proteins were extracted from the cell culture system and solubilised in urea buffer (9 M urea, 2 M thiourea and 4% CHAPS). Both onedimensional (1D) and two-dimensional (2D) gel analysis of these two proteomes show that the TSP and CF proteomes have different ...

  10. Development of bacterial cell-based system for intracellular ...

    African Journals Online (AJOL)

    Development of bacterial cell-based system for intracellular antioxidant activity screening assay using green fluorescence protein (GFP) reporter. ... Both strains demonstrated that quercetin and α- tocopherol exhibited the most potent and significant antioxidant activity with more than 60% reduction of intracellular superoxide ...

  11. Pegylated polystyrene particles as a model system for artificial cells

    NARCIS (Netherlands)

    Meng, Fenghua; Engbers, G.H.M.; Gessner, Andrea; Müller, Reiner H.; Feijen, Jan

    2004-01-01

    Pegylated polystyrene particles (PS-PEG) were prepared as a model system for artificial cells, by modification of carboxyl polystyrene particles (PS-COOH) with homo- and hetero-bifunctional polyethylene glycols (PEG, MW 1500, 3400, and 5000) containing an amino end group for immobilization and an

  12. Stem cell autotomy and niche interaction in different systems.

    Science.gov (United States)

    Dorn, David C; Dorn, August

    2015-07-26

    The best known cases of cell autotomy are the formation of erythrocytes and thrombocytes (platelets) from progenitor cells that reside in special niches. Recently, autotomy of stem cells and its enigmatic interaction with the niche has been reported from male germline stem cells (GSCs) in several insect species. First described in lepidopterans, the silkmoth, followed by the gipsy moth and consecutively in hemipterans, foremost the milkweed bug. In both, moths and the milkweed bug, GSCs form finger-like projections toward the niche, the apical cells (homologs of the hub cells in Drosophila). Whereas in the milkweed bug the projection terminals remain at the surface of the niche cells, in the gipsy moth they protrude deeply into the singular niche cell. In both cases, the projections undergo serial retrograde fragmentation with progressing signs of autophagy. In the gipsy moth, the autotomized vesicles are phagocytized and digested by the niche cell. In the milkweed bug the autotomized vesicles accumulate at the niche surface and disintegrate. Autotomy and sprouting of new projections appears to occur continuously. The significance of the GSC-niche interactions, however, remains enigmatic. Our concept on the signaling relationship between stem cell-niche in general and GSC and niche (hub cells and cyst stem cells) in particular has been greatly shaped by Drosophila melanogaster. In comparing the interactions of GSCs with their niche in Drosophila with those in species exhibiting GSC autotomy it is obvious that additional or alternative modes of stem cell-niche communication exist. Thus, essential signaling pathways, including niche-stem cell adhesion (E-cadherin) and the direction of asymmetrical GSC division - as they were found in Drosophila - can hardly be translated into the systems where GSC autotomy was reported. It is shown here that the serial autotomy of GSC projections shows remarkable similarities with Wallerian axonal destruction, developmental axon

  13. Stem cell autotomy and niche interaction in different systems

    Science.gov (United States)

    Dorn, David C; Dorn, August

    2015-01-01

    The best known cases of cell autotomy are the formation of erythrocytes and thrombocytes (platelets) from progenitor cells that reside in special niches. Recently, autotomy of stem cells and its enigmatic interaction with the niche has been reported from male germline stem cells (GSCs) in several insect species. First described in lepidopterans, the silkmoth, followed by the gipsy moth and consecutively in hemipterans, foremost the milkweed bug. In both, moths and the milkweed bug, GSCs form finger-like projections toward the niche, the apical cells (homologs of the hub cells in Drosophila). Whereas in the milkweed bug the projection terminals remain at the surface of the niche cells, in the gipsy moth they protrude deeply into the singular niche cell. In both cases, the projections undergo serial retrograde fragmentation with progressing signs of autophagy. In the gipsy moth, the autotomized vesicles are phagocytized and digested by the niche cell. In the milkweed bug the autotomized vesicles accumulate at the niche surface and disintegrate. Autotomy and sprouting of new projections appears to occur continuously. The significance of the GSC-niche interactions, however, remains enigmatic. Our concept on the signaling relationship between stem cell-niche in general and GSC and niche (hub cells and cyst stem cells) in particular has been greatly shaped by Drosophila melanogaster. In comparing the interactions of GSCs with their niche in Drosophila with those in species exhibiting GSC autotomy it is obvious that additional or alternative modes of stem cell-niche communication exist. Thus, essential signaling pathways, including niche-stem cell adhesion (E-cadherin) and the direction of asymmetrical GSC division - as they were found in Drosophila - can hardly be translated into the systems where GSC autotomy was reported. It is shown here that the serial autotomy of GSC projections shows remarkable similarities with Wallerian axonal destruction, developmental axon

  14. The role of B cells in systemic sclerosis

    Directory of Open Access Journals (Sweden)

    Marina D Kraaij

    2008-09-01

    Full Text Available Marina D Kraaij, Jacob M van LaarMusculoskeletal Research Group, Institute of Cellular Medicine, School of Clinical Medical Sciences, Newcastle University, Newcastle upon Tyne NE2 4HH, United KingdomAbstract: Systemic sclerosis (SSc is a connective disease characterized by features of autoimmunity, vasculopathy, inflammation, and fibrosis. The disease typically starts with Raynaud’s phenomenon, followed by skin thickening in the extremities due to inflammation and fibrosis. Fibrosis results from excessive collagen production by fibroblasts, which constitutes the final common pathway of complex cellular interactions including B cells. Several studies have indicated that B cells may play a role in SSc. Lesional skin infiltrates from SSc patients consist of a variety of cells, including eosinophils, neutrophils, lymphocytes, plasma cells, and macrophages. Autoantibodies of several specificities are present in the serum of SSc patients of which antitopoisomerase 1 is the most common, and evidence has been gathered for a potential pathogenic role of some autoantibodies, eg, anti-PDGF antibodies. The blood of SSc patients contains an increased proportion of naïve B cells but a decreased proportion of memory B cells. Furthermore, serum levels of interleukin-6, an important pro-inflammatory cytokine, have been shown to correlate with skin fibrosis. Animal models of SSc have provided more in-depth information on the role of B lymphocytes, eg, through disruption of B cell function. In this review we will discuss the evidence that B cells are involved in the pathogenesis of SSc.Keywords: B lymphocyte, systemic sclerosis, fibrosis

  15. Possibility of hydrogen supply by shared residential fuel cell systems for fuel cell vehicles

    Directory of Open Access Journals (Sweden)

    Ono Yusuke

    2017-01-01

    Full Text Available Residential polymer electrolyte fuel cells cogeneration systems (residential PEFC systems produce hydrogen from city gas by internal gas-reformer, and generate electricity, the hot water at the same time. From the viewpoint of the operation, it is known that residential PEFC systems do not continuously work but stop for long time, because the systems generate enough hot water for short operation time. In other words, currently residential PEFC systems are dominated by the amount of hot water demand. This study focuses on the idle time of residential PEFC systems. Since their gas-reformers are free, the systems have potential to produce hydrogen during the partial load operations. The authors expect that residential PEFC systems can take a role to supply hydrogen for fuel cell vehicles (FCVs before hydrogen fueling stations are distributed enough. From this perspective, the objective of this study is to evaluate the hydrogen production potential of residential PEFC systems. A residential PEFC system was modeled by the mixed integer linear programming to optimize the operation including hydrogen supply for FCV. The objective function represents annual system cost to be minimized with the constraints of energy balance. It should be noted that the partial load characteristics of the gas-reformer and the fuel cell stack are taken into account to derive the optimal operation. The model was employed to estimate the possible amount of hydrogen supply by a residential PEFC system. The results indicated that the system could satisfy at least hydrogen demand for transportation of 8000 km which is as far as the average annual mileage of a passenger car in Japan. Furthermore, hydrogen production by sharing a residential PEFC system with two households is more effective to reduce primary energy consumption with hydrogen supply for FCV than the case of introducing PEFC in each household.

  16. A human thymic epithelial cell culture system for the promotion of lymphopoiesis from hematopoietic stem cells.

    Science.gov (United States)

    Beaudette-Zlatanova, Britte C; Knight, Katherine L; Zhang, Shubin; Stiff, Patrick J; Zúñiga-Pflücker, Juan Carlos; Le, Phong T

    2011-05-01

    A human thymic epithelial cell (TEC) line expressing human leukocyte antigen-ABC and human leukocyte antigen-DR was engineered to overexpress murine Delta-like 1 (TEC-Dl1) for the purpose of establishing a human culture system that supports T lymphopoiesis from hematopoietic progenitor cells (HPCs). Cord blood or bone marrow HPCs were co-cultured with either the parental TEC line expressing low levels of the Notch ligands, Delta-like 1 and Delta-like 4, or with TEC-Dl1 to determine if these cell lines support human lymphopoiesis. In co-cultures with cord blood or bone marrow HPCs, TEC-Dl1 cells promote de novo generation of CD7(pos)CD1a(pos) T-lineage committed cells. Most CD7(pos)CD1a(hi) cells are CD4(pos)CD8(pos) double-positive (DP). We found that TEC-Dl1 cells are insufficient to generate mature CD3(hi) CD4(pos) or CD3(hi) CD8(pos) single-positive (SP) T cells from the CD4(pos)CD8(pos) DP T cells; however, we detected CD3(lo) cells within the DP and SP CD4 and CD8 populations. The CD3(lo) SP cells expressed lower levels of interleukin-2Rα and interleukin-7Rα compared to CD3(lo) DP cells. In contrast to the TEC-Dl1 line, the parental TEC-84 line expressing low levels of human Notch ligands permits HPC differentiation to the B-cell lineage. We report for the first time a human TEC line that supports lymphopoiesis from cord blood and bone marrow HPC. The TEC cell lines described herein provide a novel human thymic stroma model to study the contribution of human leukocyte antigen molecules and Notch ligands to T-cell commitment and maturation and could be utilized to promote lymphopoiesis for immune cell therapy. Copyright © 2011 ISEH - Society for Hematology and Stem Cells. Published by Elsevier Inc. All rights reserved.

  17. Generation of a Drug-inducible Reporter System to Study Cell Reprogramming in Human Cells*

    Science.gov (United States)

    Ruiz, Sergio; Panopoulos, Athanasia D.; Montserrat, Nuria; Multon, Marie-Christine; Daury, Aurélie; Rocher, Corinne; Spanakis, Emmanuel; Batchelder, Erika M.; Orsini, Cécile; Deleuze, Jean-François; Izpisua Belmonte, Juan Carlos

    2012-01-01

    Reprogramming of somatic cells into induced pluripotent stem cells is achieved by the expression of defined transcription factors. In the last few years, reprogramming strategies on the basis of doxycycline-inducible lentiviruses in mouse cells became highly powerful for screening purposes when the expression of a GFP gene, driven by the reactivation of endogenous stem cell specific promoters, was used as a reprogramming reporter signal. However, similar reporter systems in human cells have not been generated. Here, we describe the derivation of drug-inducible human fibroblast-like cell lines that express different subsets of reprogramming factors containing a GFP gene under the expression of the endogenous OCT4 promoter. These cell lines can be used to screen functional substitutes for reprogramming factors or modifiers of reprogramming efficiency. As a proof of principle of this system, we performed a screening of a library of pluripotent-enriched microRNAs and identified hsa-miR-519a as a novel inducer of reprogramming efficiency. PMID:23019325

  18. Current reprogramming systems in regenerative medicine: from somatic cells to induced pluripotent stem cells.

    Science.gov (United States)

    Hu, Chenxia; Li, Lanjuan

    2016-01-01

    Induced pluripotent stem cells (iPSCs) paved the way for research fields including cell therapy, drug screening, disease modeling and the mechanism of embryonic development. Although iPSC technology has been improved by various delivery systems, direct transduction and small molecule regulation, low reprogramming efficiency and genomic modification steps still inhibit its clinical use. Improvements in current vectors and the exploration of novel vectors are required to balance efficiency and genomic modification for reprogramming. Herein, we set out a comprehensive analysis of current reprogramming systems for the generation of iPSCs from somatic cells. By clarifying advantages and disadvantages of the current reprogramming systems, we are striding toward an effective route to generate clinical grade iPSCs.

  19. SMALL SCALE FUEL CELL AND REFORMER SYSTEMS FOR REMOTE POWER

    Energy Technology Data Exchange (ETDEWEB)

    Dennis Witmer

    2003-12-01

    New developments in fuel cell technologies offer the promise of clean, reliable affordable power, resulting in reduced environmental impacts and reduced dependence on foreign oil. These developments are of particular interest to the people of Alaska, where many residents live in remote villages, with no roads or electrical grids and a very high cost of energy, where small residential power systems could replace diesel generators. Fuel cells require hydrogen for efficient electrical production, however. Hydrogen purchased through conventional compressed gas suppliers is very expensive and not a viable option for use in remote villages, so hydrogen production is a critical piece of making fuel cells work in these areas. While some have proposed generating hydrogen from renewable resources such as wind, this does not appear to be an economically viable alternative at this time. Hydrogen can also be produced from hydrocarbon feed stocks, in a process known as reforming. This program is interested in testing and evaluating currently available reformers using transportable fuels: methanol, propane, gasoline, and diesel fuels. Of these, diesel fuels are of most interest, since the existing energy infrastructure of rural Alaska is based primarily on diesel fuels, but this is also the most difficult fuel to reform, due to the propensity for coke formation, due to both the high vaporization temperature and to the high sulfur content in these fuels. There are several competing fuel cell technologies being developed in industry today. Prior work at UAF focused on the use of PEM fuel cells and diesel reformers, with significant barriers identified to their use for power in remote areas, including stack lifetime, system efficiency, and cost. Solid Oxide Fuel Cells have demonstrated better stack lifetime and efficiency in demonstrations elsewhere (though cost still remains an issue), and procuring a system for testing was pursued. The primary function of UAF in the fuel cell

  20. [The cell as a gravity-dependent biomechanic system].

    Science.gov (United States)

    Tairbekov, M G

    2000-01-01

    In the period of 1995-1997 experimental and theoretical studies with various biomechanic objects, i.e. individual cells and cell associations, were performed under changed gravity (0.00001-5 g). Experimental investigations were conducted using clinostats and centrifuges to model effects of hypo- and hypergravity, and aboard space vehicles in real microgravity. Cell cultures in vitro including fibroblasts and osteoblasts on a solid glass or plastic substrate served as objects of the studies. Changes in value and direction of the gravity vector were found to modify the morphophysiological characteristics of cells: structural organization (spatial rearrangement of the intracell component, changes in forms, sizes and quantity of cells) and functional activity (alterations in energy expenditure and intensity of intracellular metabolism). The data suggest that there should be mechanisms of gravitational sensitivity in living systems on the cellular level. As was stated, sensitivity of unicellular free-living organisms to gravity is mostly defined by the motor activity determined by the level of general metabolism. Morphological characteristics (form, size and mass) are of secondary importance. Theoretical analysis resulted in correction of one of the principle postulates of gravitational biology stating a direct link between size (mass) and gravitational sensitivity of organism. Described were consistent patterns of growth, development, and behavior of unicellular cultures in gravitational fields. Strengthening of the force of gravity (hypergravity) leads to eventual deceleration of cell growth and diminution of biomass gain. On the other hand, the spaceflight environment (microgravity) stimulates growth mechanisms. In our opinion, behind these gravitational effects are altered levels of energy spent by cells to overcome the force of gravity. Opposite trends were observed in experiments with cell cultures in vitro. During space microgravity, fibroblast cultures on the

  1. Scheduling of Power System Cells Integrating Stochastic Power Generation

    International Nuclear Information System (INIS)

    Costa, L.M.

    2008-12-01

    Energy supply and climate change are nowadays two of the most outstanding problems which societies have to cope with under a context of increasing energy needs. Public awareness of these problems is driving political willingness to take actions for tackling them in a swift and efficient manner. Such actions mainly focus in increasing energy efficiency, in decreasing dependence on fossil fuels, and in reducing greenhouse gas emissions. In this context, power systems are undergoing important changes in the way they are planned and managed. On the one hand, vertically integrated structures are being replaced by market structures in which power systems are un-bundled. On the other, power systems that once relied on large power generation facilities are witnessing the end of these facilities' life-cycle and, consequently, their decommissioning. The role of distributed energy resources such as wind and solar power generators is becoming increasingly important in this context. However, the large-scale integration of such type of generation presents many challenges due, for instance, to the uncertainty associated to the variability of their production. Nevertheless, advanced forecasting tools may be combined with more controllable elements such as energy storage devices, gas turbines, and controllable loads to form systems that aim to reduce the impacts that may be caused by these uncertainties. This thesis addresses the management under market conditions of these types of systems that act like independent societies and which are herewith named power system cells. From the available literature, a unified view of power system scheduling problems is also proposed as a first step for managing sets of power system cells in a multi-cell management framework. Then, methodologies for performing the optimal day-ahead scheduling of single power system cells are proposed, discussed and evaluated under both a deterministic and a stochastic framework that directly integrates the

  2. An automated system for high-throughput single cell-based breeding

    Science.gov (United States)

    Yoshimoto, Nobuo; Kida, Akiko; Jie, Xu; Kurokawa, Masaya; Iijima, Masumi; Niimi, Tomoaki; Maturana, Andrés D.; Nikaido, Itoshi; Ueda, Hiroki R.; Tatematsu, Kenji; Tanizawa, Katsuyuki; Kondo, Akihiko; Fujii, Ikuo; Kuroda, Shun'ichi

    2013-01-01

    When establishing the most appropriate cells from the huge numbers of a cell library for practical use of cells in regenerative medicine and production of various biopharmaceuticals, cell heterogeneity often found in an isogenic cell population limits the refinement of clonal cell culture. Here, we demonstrated high-throughput screening of the most suitable cells in a cell library by an automated undisruptive single-cell analysis and isolation system, followed by expansion of isolated single cells. This system enabled establishment of the most suitable cells, such as embryonic stem cells with the highest expression of the pluripotency marker Rex1 and hybridomas with the highest antibody secretion, which could not be achieved by conventional high-throughput cell screening systems (e.g., a fluorescence-activated cell sorter). This single cell-based breeding system may be a powerful tool to analyze stochastic fluctuations and delineate their molecular mechanisms. PMID:23378922

  3. NASA Lewis Evaluation of Regenerative Fuel Cell (RFC) Systems

    Science.gov (United States)

    Hagedorn, N. H.; Gonzalez-Sanabria, O. D; Kohout, L. L.

    1986-01-01

    Evaluation of two regenerative fuel cell (RFC) systems was begun in-house, and under contracts and grants. The passive hydrogen-oxygen RFC offers the possibility of a high-energy density, long-life storage system for geosynchronous Earth orbit missions. The hydrogen-bromine RFC offers the combination of high efficiency and moderate energy density that could ideally suit low Earth orbit missions if successfully developed. Either or both of these systems would be attractive additions to the storage options available to designers of future missions.

  4. A combined capillary cooling system for cooling fuel cells

    Energy Technology Data Exchange (ETDEWEB)

    Silva, Ana Paula; Pelizza, Pablo Rodrigo; Galante, Renan Manozzo; Bazzo, Edson [Universidade Federal de Santa Catarina (LabCET/UFSC), Florianopolis, SC (Brazil). Dept. de Engenharia Mecanica. Lab. de Combustao e Engenharia de Sistemas Termicos], Emails: ana@labcet.ufsc.br, pablo@labcet.ufsc.br, renan@labcet.ufsc.br, ebazzo@emc.ufsc.br

    2010-07-01

    The operation temperature control has an important influence over the PEMFC (Proton Exchange Membrane Fuel Cell) performance. A two-phase heat transfer system is proposed as an alternative for cooling and thermal control of PEMFC. The proposed system consists of a CPL (Capillary Pumped Loop) connected to a set of constant conductance heat pipes. In this work ceramic wick and stainless mesh wicks have been used as capillary structure of the CPL and heat pipes, respectively. Acetone has been used as the working fluid for CPL and deionized water for the heat pipes. Experimental results of three 1/4 inch stainless steel outlet diameter heats pipes and one CPL have been carried out and presented in this paper. Further experiments are planned coupling the proposed cooling system to a module which simulates the fuel cell. (author)

  5. Reactivation System for Proton-Exchange Membrane Fuel-Cells

    Directory of Open Access Journals (Sweden)

    Roberto Giral

    2012-07-01

    Full Text Available In recent years, Proton-Exchange Membrane Fuel Cells (PEMFCs have been the focus of very intensive researches. Manufacturers of these alternative power sources propose a rejuvenation sequence after the FC has been operating at high power for a certain period of time. These rejuvenation methods could be not appropriate for the reactivation of the FC when it has been out of operation for a long period of time or after it has been repaired. Since the developed reactivation system monitors temperature, current, and the cell voltages of the stack, it could be also useful for the diagnostic and repairing processes. The limited number of published contributions suggests that systems developing reactivation techniques are an open research field. In this paper, an automated system for reactivating PEMFCs and results of experimental testing are presented.

  6. Growth of primary embryo cells in a microculture system.

    Science.gov (United States)

    Villa, Max; Pope, Sara; Conover, Joanne; Fan, Tai-Hsi

    2010-04-01

    We present optimal perfusion conditions for the growth of primary mouse embryonic fibroblasts (mEFs) and mouse embryonic stem cells (mESCs) using a microfluidic perfusion culture system. In an effort to balance nutrient renewal while ensuring the presence of cell secreted factors, we found that the optimal perfusion rate for culturing primary embryonic fibroblasts (mEFs) in our experimental setting is 10 nL/min with an average flow velocity 0.55 microm/s in the microchannel. Primary mEFs may have a greater dependence on cell secreted factors when compared to their immortalized counterpart 3T3 fibroblasts cultured under similar conditions. Both the seeding density and the perfusion rate are critical for the proliferation of primary cells. A week long cultivation of mEFs and mESCs using the microculture system exhibited similar morphology and viability to those grown in a petri dish. Both mEFs and mESCs were analyzed using fluorescence immunoassays to determine their proliferative status and protein expression. Our results demonstrate that a perfusion-based microculture environment is capable of supporting the highly proliferative status of pluripotent embryonic stem cells.

  7. System identification and robust control of a portable proton exchange membrane full-cell system

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Fu-Cheng; Yang, Yee-Pien; Huang, Chi-Wei; Chen, Hsuan-Tsung [Department of Mechanical Engineering, National Taiwan University, Taipei (Taiwan); Chang, Hsin-Ping [Chung Shan Institute of Science and Technology (CSIST), Armaments Bureau, M.N.D (Taiwan)

    2007-02-10

    This paper will discuss the application of system identification techniques and robust control strategies to a proton exchange membrane fuel-cell system. The fuel-cell system's dynamic behaviour is influenced by many factors, such as the reaction mechanism, pressure, flow-rate, composition and temperature change, and is inherently non-linear and time varying. From a system point of view, however, the system can be modelled as a two-input, two-output linear time-invariant system whose inputs are hydrogen and air flow rates, and whose outputs are cell voltage and current. On the other hand, the system's non-linearities and time-varying characteristics can be regarded as system uncertainties and disturbances that are treated by the designed robust controllers. This paper is comprised of three parts. First, system identification techniques were adopted to model the system's transfer functions. Second, the H{sub {infinity}} robust control strategies were applied to stabilise the system. Finally, the system's stability and performance were compromised by introducing weighting functions to the controller's design. From the experimental results, the designed H{sub {infinity}} robust controllers were deemed effective. (author)

  8. Planning for a Low Carbon Future? Comparing Heat Pumps and Cogeneration as the Energy System Options for a New Residential Area

    Directory of Open Access Journals (Sweden)

    Jukka Heinonen

    2015-08-01

    Full Text Available The purpose of this paper is to compare, from an urban planning perspective, the choice between combined heat and power (CHP and a ground-source heat pump (HP as the energy systems of a new residential area in the light of the uncertainty related to the assessments. There has been a strong push globally for CHP due to its climate mitigation potential compared to separate production, and consequently it is often prioritized in planning without questioning. However, the uncertainties in assessing the emissions from CHP and alternative options in a certain planning situation make it very difficult to give robust decision guidelines. In addition, even the order of magnitude of the climate impact of a certain plan is actually difficult to assess robustly. With a case study of the new residential development of Härmälänranta in Tampere, Finland, we show how strongly the uncertainties related to (1 utilizing average or marginal electricity as the reference; (2 assigning emissions intensities for the production; and (3 allocating the emissions from CHP to heat and electricity affect the results and lead to varying decision guidelines. We also depict how a rather rarely utilized method in assigning the emissions from CHP is the most robust for planning support.

  9. Final Technical Report: Affordable, High-Performance, Intermediate Temperature Solid Oxide Fuel Cells

    Energy Technology Data Exchange (ETDEWEB)

    Blackburn, Bryan [Redox Power Systems, LLC; Bishop, Sean [Redox Power Systems, LLC; Gore, Colin [Redox Power Systems, LLC; Wang, Lei [Redox Power Systems, LLC; Correa, Luis [Redox Power Systems, LLC; Langdo, Thomas [Redox Power Systems, LLC; Deaconu, Stelu [Redox Power Systems, LLC; Pan, Keji [Redox Power Systems, LLC

    2018-02-15

    In this project, we improved the power output and voltage efficiency of our intermediate temperature solid oxide fuel cells (IT-SOFCs) with a focus on ~600 °C operation. At these temperatures and with the increased power density (i.e., fewer cells for same power output), the stack cost should be greatly reduced while extending durability. Most SOFC stacks operate at temperatures greater than 800 °C. This can greatly increase the cost of the system (stacks and BOP) as well as maintenance costs since the most common degradation mechanisms are thermally driven. Our approach uses no platinum group metal (PGM) materials and the lower operating temperature allows use of simple stainless steel interconnects and commercial off-the-shelf gaskets in the stack. Furthermore, for combined heating and power (CHP) applications the stack exhaust still provides “high quality” waste heat that can be recovered and used in a chiller or boiler. The anticipated performance, durability, and resulting cost improvements (< $700/kWe) will also move us closer to reaching the full potential of this technology for distributed generation (DG) and residential/commercial CHP. This includes eventual extension to cleaner, more efficient portable generators, auxiliary power units (APUs), and range extenders for transportation. The research added to the understanding of the area investigated by exploring various methods for increasing power density (Watts/square centimeter of active area in each cell) and increasing cell efficiency (increasing the open circuit voltage, or cell voltage with zero external electrical current). The results from this work demonstrated an optimized cell that had greater than 1 W/cm2 at 600 °C and greater than 1.6 W/cm2 at 650 °C. This was demonstrated in large format sizes using both 5 cm by 5 cm and 10 cm by 10 cm cells. Furthermore, this work demonstrated that high stability (no degradation over > 500 hours) can be achieved together with high performance in large

  10. Systems Biology Perspectives on Minimal and Simpler Cells

    Science.gov (United States)

    Xavier, Joana C.; Patil, Kiran Raosaheb

    2014-01-01

    SUMMARY The concept of the minimal cell has fascinated scientists for a long time, from both fundamental and applied points of view. This broad concept encompasses extreme reductions of genomes, the last universal common ancestor (LUCA), the creation of semiartificial cells, and the design of protocells and chassis cells. Here we review these different areas of research and identify common and complementary aspects of each one. We focus on systems biology, a discipline that is greatly facilitating the classical top-down and bottom-up approaches toward minimal cells. In addition, we also review the so-called middle-out approach and its contributions to the field with mathematical and computational models. Owing to the advances in genomics technologies, much of the work in this area has been centered on minimal genomes, or rather minimal gene sets, required to sustain life. Nevertheless, a fundamental expansion has been taking place in the last few years wherein the minimal gene set is viewed as a backbone of a more complex system. Complementing genomics, progress is being made in understanding the system-wide properties at the levels of the transcriptome, proteome, and metabolome. Network modeling approaches are enabling the integration of these different omics data sets toward an understanding of the complex molecular pathways connecting genotype to phenotype. We review key concepts central to the mapping and modeling of this complexity, which is at the heart of research on minimal cells. Finally, we discuss the distinction between minimizing the number of cellular components and minimizing cellular complexity, toward an improved understanding and utilization of minimal and simpler cells. PMID:25184563

  11. Signal transduction in cells of the immune system in microgravity

    Directory of Open Access Journals (Sweden)

    Huber Kathrin

    2008-10-01

    Full Text Available Abstract Life on Earth developed in the presence and under the constant influence of gravity. Gravity has been present during the entire evolution, from the first organic molecule to mammals and humans. Modern research revealed clearly that gravity is important, probably indispensable for the function of living systems, from unicellular organisms to men. Thus, gravity research is no more or less a fundamental question about the conditions of life on Earth. Since the first space missions and supported thereafter by a multitude of space and ground-based experiments, it is well known that immune cell function is severely suppressed in microgravity, which renders the cells of the immune system an ideal model organism to investigate the influence of gravity on the cellular and molecular level. Here we review the current knowledge about the question, if and how cellular signal transduction depends on the existence of gravity, with special focus on cells of the immune system. Since immune cell function is fundamental to keep the organism under imnological surveillance during the defence against pathogens, to investigate the effects and possible molecular mechanisms of altered gravity is indispensable for long-term space flights to Earth Moon or Mars. Thus, understanding the impact of gravity on cellular functions on Earth will provide not only important informations about the development of life on Earth, but also for therapeutic and preventive strategies to cope successfully with medical problems during space exploration.

  12. Epigenetics, Nervous System Tumors, and Cancer Stem Cells

    International Nuclear Information System (INIS)

    Qureshi, Irfan A.; Mehler, Mark F.

    2011-01-01

    Recent advances have begun to elucidate how epigenetic regulatory mechanisms are responsible for establishing and maintaining cell identity during development and adult life and how the disruption of these processes is, not surprisingly, one of the hallmarks of cancer. In this review, we describe the major epigenetic mechanisms (i.e., DNA methylation, histone and chromatin modification, non-coding RNA deployment, RNA editing, and nuclear reorganization) and discuss the broad spectrum of epigenetic alterations that have been uncovered in pediatric and adult nervous system tumors. We also highlight emerging evidence that suggests epigenetic deregulation is a characteristic feature of so-called cancer stem cells (CSCs), which are thought to be present in a range of nervous system tumors and responsible for tumor maintenance, progression, treatment resistance, and recurrence. We believe that better understanding how epigenetic mechanisms operate in neural cells and identifying the etiologies and consequences of epigenetic deregulation in tumor cells and CSCs, in particular, are likely to promote the development of enhanced molecular diagnostics and more targeted and effective therapeutic agents for treating recalcitrant nervous system tumors

  13. Epigenetics, Nervous System Tumors, and Cancer Stem Cells

    Energy Technology Data Exchange (ETDEWEB)

    Qureshi, Irfan A. [Rosyln and Leslie Goldstein Laboratory for Stem Cell Biology and Regenerative Medicine, Albert Einstein College of Medicine, Bronx, New York, NY 10461 (United States); Institute for Brain Disorders and Neural Regeneration, Albert Einstein College of Medicine, Bronx, New York, NY 10461 (United States); Department of Neurology, Albert Einstein College of Medicine, Bronx, New York, NY 10461 (United States); Rose F. Kennedy Center for Research on Intellectual and Developmental Disabilities, Albert Einstein College of Medicine, Bronx, New York, NY 10461 (United States); Mehler, Mark F., E-mail: mark.mehler@einstein.yu.edu [Rosyln and Leslie Goldstein Laboratory for Stem Cell Biology and Regenerative Medicine, Albert Einstein College of Medicine, Bronx, New York, NY 10461 (United States); Institute for Brain Disorders and Neural Regeneration, Albert Einstein College of Medicine, Bronx, New York, NY 10461 (United States); Department of Neurology, Albert Einstein College of Medicine, Bronx, New York, NY 10461 (United States); Department of Neuroscience, Albert Einstein College of Medicine, Bronx, New York, NY 10461 (United States); Department of Psychiatry and Behavioral Sciences, Albert Einstein College of Medicine, Bronx, New York, NY 10461 (United States); Rose F. Kennedy Center for Research on Intellectual and Developmental Disabilities, Albert Einstein College of Medicine, Bronx, New York, NY 10461 (United States)

    2011-09-13

    Recent advances have begun to elucidate how epigenetic regulatory mechanisms are responsible for establishing and maintaining cell identity during development and adult life and how the disruption of these processes is, not surprisingly, one of the hallmarks of cancer. In this review, we describe the major epigenetic mechanisms (i.e., DNA methylation, histone and chromatin modification, non-coding RNA deployment, RNA editing, and nuclear reorganization) and discuss the broad spectrum of epigenetic alterations that have been uncovered in pediatric and adult nervous system tumors. We also highlight emerging evidence that suggests epigenetic deregulation is a characteristic feature of so-called cancer stem cells (CSCs), which are thought to be present in a range of nervous system tumors and responsible for tumor maintenance, progression, treatment resistance, and recurrence. We believe that better understanding how epigenetic mechanisms operate in neural cells and identifying the etiologies and consequences of epigenetic deregulation in tumor cells and CSCs, in particular, are likely to promote the development of enhanced molecular diagnostics and more targeted and effective therapeutic agents for treating recalcitrant nervous system tumors.

  14. The Purinergic System and Glial Cells: Emerging Costars in Nociception

    Directory of Open Access Journals (Sweden)

    Giulia Magni

    2014-01-01

    Full Text Available It is now well established that glial cells not only provide mechanical and trophic support to neurons but can directly contribute to neurotransmission, for example, by release and uptake of neurotransmitters and by secreting pro- and anti-inflammatory mediators. This has greatly changed our attitude towards acute and chronic disorders, paving the way for new therapeutic approaches targeting activated glial cells to indirectly modulate and/or restore neuronal functions. A deeper understanding of the molecular mechanisms and signaling pathways involved in neuron-to-glia and glia-to-glia communication that can be pharmacologically targeted is therefore a mandatory step toward the success of this new healing strategy. This holds true also in the field of pain transmission, where the key involvement of astrocytes and microglia in the central nervous system and satellite glial cells in peripheral ganglia has been clearly demonstrated, and literally hundreds of signaling molecules have been identified. Here, we shall focus on one emerging signaling system involved in the cross talk between neurons and glial cells, the purinergic system, consisting of extracellular nucleotides and nucleosides and their membrane receptors. Specifically, we shall summarize existing evidence of novel “druggable” glial purinergic targets, which could help in the development of innovative analgesic approaches to chronic pain states.

  15. Fabrication and Characterization of Copper System Compound Semiconductor Solar Cells

    Directory of Open Access Journals (Sweden)

    Ryosuke Motoyoshi

    2010-01-01

    Full Text Available Copper system compound semiconductor solar cells were produced by a spin-coating method, and their cell performance and structures were investigated. Copper indium disulfide- (CIS- based solar cells with titanium dioxide (TiO2 were produced on F-doped SnO2 (FTO. A device based on an FTO/CIS/TiO2 structure provided better cell performance compared to that based on FTO/TiO2/CIS structure. Cupric oxide- (CuO- and cuprous oxide- (Cu2O- based solar cells with fullerene (C60 were also fabricated on FTO and indium tin oxide (ITO. The microstructure and cell performance of the CuO/C60 heterojunction and the Cu2O:C60 bulk heterojunction structure were investigated. The photovoltaic devices based on FTO/CuO/C60 and ITO/Cu2O:C60 structures provided short-circuit current density of 0.015 mAcm−2 and 0.11 mAcm−2, and open-circuit voltage of 0.045 V and 0.17 V under an Air Mass 1.5 illumination, respectively. The microstructures of the active layers were examined by X-ray diffraction and transmission electron microscopy.

  16. Hydrogen Fuel Cell on a Helicopter: A System Engineering Approach

    Science.gov (United States)

    Nesheiwat, Rod

    Hydrogen fuel cells have been previously investigated as a viable replacement to traditional gas turbine auxiliary power unit onboard fixed wing commercial jets. However, so far no study has attempted to extend their applicability to rotary wing aircrafts. To aid in the advancement of such innovative technologies, a holistic technical approach is required to ensure risk reduction and cost effectiveness throughout the product lifecycle. This paper will evaluate the feasibility of replacing a gas turbine auxiliary power unit on a helicopter with a direct hydrogen, air breathing, proton exchange membrane fuel cell, all while emphasizing a system engineering approach that utilize a specialized set of tools and artifacts.

  17. PRESSURIZED SOLID OXIDE FUEL CELL/GAS TURBINE POWER SYSTEM

    Energy Technology Data Exchange (ETDEWEB)

    W.L. Lundberg; G.A. Israelson; R.R. Moritz(Rolls-Royce Allison); S.E. Veyo; R.A. Holmes; P.R. Zafred; J.E. King; R.E. Kothmann (Consultant)

    2000-02-01

    Power systems based on the simplest direct integration of a pressurized solid oxide fuel cell (SOFC) generator and a gas turbine (GT) are capable of converting natural gas fuel energy to electric power with efficiencies of approximately 60% (net AC/LHV), and more complex SOFC and gas turbine arrangements can be devised for achieving even higher efficiencies. The results of a project are discussed that focused on the development of a conceptual design for a pressurized SOFC/GT power system that was intended to generate 20 MWe with at least 70% efficiency. The power system operates baseloaded in a distributed-generation application. To achieve high efficiency, the system integrates an intercooled, recuperated, reheated gas turbine with two SOFC generator stages--one operating at high pressure, and generating power, as well as providing all heat needed by the high-pressure turbine, while the second SOFC generator operates at a lower pressure, generates power, and provides all heat for the low-pressure reheat turbine. The system cycle is described, major system components are sized, the system installed-cost is estimated, and the physical arrangement of system components is discussed. Estimates of system power output, efficiency, and emissions at the design point are also presented, and the system cost of electricity estimate is developed.

  18. SECA Coal-Based Systems - FuelCell Energy, Inc.

    Energy Technology Data Exchange (ETDEWEB)

    Ayagh, Hossein [Fuelcell Energy, Inc., Danbury, CT (United States)

    2014-01-31

    The overall goal of this U.S. Department of Energy (DOE) sponsored project is the development of solid oxide fuel cell (SOFC) cell and stack technology suitable for use in highly-efficient, economically-competitive central generation power plant facilities fueled by coal synthesis gas (syngas). This program incorporates the following supporting objectives: • Reduce SOFC-based electrical power generation system cost to $700 or less (2007 dollars) for a greater than 100 MW Integrated Gasification Fuel Cell (IGFC) power plant, exclusive of coal gasification and CO2 separation subsystem costs. • Achieve an overall IGFC power plant efficiency of at least 50%, from coal (higher heating value or HHV) to AC power (exclusive of CO2 compression power requirement). • Reduce the release of CO2 to the environment in an IGFC power plant to no more than 10% of the carbon in the syngas. • Increase SOFC stack reliability to achieve a design life of greater than 40,000 hours. At the inception of the project, the efforts were focused on research, design and testing of prototype planar SOFC power generators for stationary applications. FuelCell Energy, Inc. successfully completed the initial stage of the project by meeting the program metrics, culminating in delivery and testing of a 3 kW system at National Energy Technology Laboratory (NETL). Subsequently, the project was re-aligned into a three phase effort with the main goal to develop SOFC technology for application in coal-fueled power plants with >90% carbon capture. Phase I of the Coal-based efforts focused on cell and stack size scale-up with concurrent enhancement of performance, life, cost, and manufacturing characteristics. Also in Phase I, design and analysis of the baseline (greater than 100 MW) power plant system—including concept identification, system definition, and cost analysis—was conducted. Phase II efforts focused on development of a ≥25 kW SOFC stack tower incorporating

  19. [Biological characteristics of mesenchymal stem cell and hematopoietic stem cell in the co-culture system].

    Science.gov (United States)

    Wei, Wei; Xu, Chao; Ye, Zhi-Yong; Huang, Xiao-Jun; Yuan, Jia-En; Ma, Tian-Bao; Lin, Han-Biao; Chen, Xiu-Qiong

    2016-10-25

    The aim of the present study was to obtain the qualified hematopoietic stem/progenitor cells (HSC/HPC) and human umbilical cord-mesenchymal stem cells (MSC) in vitro in the co-culture system. Cord blood mononuclear cells were separated from umbilical cord blood by Ficoll lymphocyte separation medium, and then CD34 + HSC was collected by MACS immunomagnetic beads. The selected CD34 + HSC/HPC and MSC were transferred into culture flask. IMDM culture medium with 15% AB-type cord plasma supplemented with interleukin-3 (IL-3), IL-6, thrombopoietin (TPO), stem cell factor (SCF) and FMS-like tyrosine kinase 3 ligand (Flt-3L) factors were used as the co-culture system for the amplification of HSC/HPC and MSC. The cellular growth status and proliferation on day 6 and 10 after co-culture were observed by using inverted microscope. The percentage of positive expression of CD34 in HSC/HPC, as well as the percentages of positive expressions of CD105, CD90, CD73, CD45, CD34 and HLA-DR in the 4 th generation MSC, was tested by flow cytometry. Semisolid colony culture was used to test the HSC/HPC colony forming ability. The osteogenic, chondrogenesis and adipogenic ability of the 4 th generation MSC were assessed. The karyotype analysis of MSC was conducted by colchicines. The results demonstrated that the HSC/HPC of co-culture group showed higher ability of amplification, CFU-GM and higher CD34 + percentage compared with the control group. The co-cultured MSC maintained the ability to differentiate into bone cells, fat cells and chondrocytes. And the karyotype stability of MSC remained normal. These results reveal that the appropriate co-culture system for MSC and HSC is developed, and via this co-culture system we could gain both two kinds of these cells. The MSCs under the co-culture system maintain the biological characteristics. The CFU-GM ability, cell counting and the flow cytometry results of HSC/HPC under the co-culture system are conform to the criterion, showing that

  20. Method for operating a combustor in a fuel cell system

    Science.gov (United States)

    Chalfant, Robert W.; Clingerman, Bruce J.

    2002-01-01

    A method of operating a combustor to heat a fuel processor in a fuel cell system, in which the fuel processor generates a hydrogen-rich stream a portion of which is consumed in a fuel cell stack and a portion of which is discharged from the fuel cell stack and supplied to the combustor, and wherein first and second streams are supplied to the combustor, the first stream being a hydrocarbon fuel stream and the second stream consisting of said hydrogen-rich stream, the method comprising the steps of monitoring the temperature of the fuel processor; regulating the quantity of the first stream to the combustor according to the temperature of the fuel processor; and comparing said quantity of said first stream to a predetermined value or range of predetermined values.