WorldWideScience

Sample records for cell bus program

  1. Hydrogen Bus Technology Validation Program

    OpenAIRE

    Burke, Andy; McCaffrey, Zach; Miller, Marshall; Collier, Kirk; Mulligan, Neal

    2005-01-01

    Heavy duty engines are substantial contributors to NOX and PM emissions inventories in urban areas, and stringent emissions standards have been adopted as a consequence. CARB has passed very strict emissions standards for heavy duty engines beginning in 2007. Meeting these standards, especially for NOX emissions, may be difficult for conventional transit bus technologies. The purpose of the Hydrogen Bus Technology Evaluation Program was to develop and evaluate hydrogen enriched natural gas (H...

  2. National Fuel Cell Bus Program: Accelerated Testing Evaluation Report and Appendices, Alameda-Contra Costa Transit District (AC Transit)

    Energy Technology Data Exchange (ETDEWEB)

    Chandler, K.; Eudy, L.

    2009-01-01

    This is an evaluation of hydrogen fuel cell transit buses operating at AC Transit in revenue service since March 20, 2006 compared to similar diesel buses operating from the same depot. This evaluation report includes results from November 2007 through October 2008. Evaluation results include implementation experience, fueling station operation, fuel cell bus operations at Golden Gate Transit, and evaluation results at AC Transit (bus usage, availability, fuel economy, maintenance costs, and roadcalls).

  3. Hybrid fuel cell bus demonstration: advanced technology moves bus forward

    International Nuclear Information System (INIS)

    The Province of Manitoba has been actively pursuing hydrogen since 2001 as one part of a portfolio of renewable energy alternatives. Six priority hydrogen actions have been underway covering a variety of opportunities, including two recently completed major transit bus and refueling demonstrations. A brief overview of Manitoba's activities on hydrogen will be provided, emphasizing the lessons learned from recent projects such as the hydrogen Hybrid Fuel Cell Bus demonstration, and in particular implications for the research community. (author)

  4. Overview about the fuel cell bus demonstration programs CUTE, ECTOS and STEP

    International Nuclear Information System (INIS)

    'Full text:' The paper will give an overview about the CUTE, ECTOS and STEP projects. The aim of the projects is to develop and demonstrate a emission-free and low-noise transport system, including the accompanying energy infrastructure, which has great potential for reducing the global greenhouse effect according to the Kyoto protocol, improving the quality of the atmosphere and life in densely populated areas and conserving fossil resources. For this purpose the application of the innovative hydrogen-based fuel cell technology is established by using fuel cell powered buses in an urban environment together with novel hydrogen production and support systems as part of a European Union wide demonstration scheme. The project demonstrates also to European Society the availability of the FC technology as a safe and reliable transportation technology. The major objectives are as follows: Demonstration of more than 20 fuel cell powered regular service buses over a period of two years in several European inner city areas to illustrate the different operating conditions to be found in Europe; Design, construction and operation of the necessary infrastructure for hydrogen production, including the required refuelling stations; Collection of findings concerning the construction and operating behaviour of hydrogen production for mobile use, and exchange of experiences including bus operation under differing conditions among the numerous participating companies; and, the research work of IKP and PE comprises the ecological analysis of the entire life cycle and comparison with conventional alternatives (diesel driven buses, CNG-buses). It also includes the economical analysis of the hydrogen infrastructure. First experiences from CUTE and ECTOS were presented. (author)

  5. 77 FR 48592 - Bus and Bus Facilities Discretionary Program Funds

    Science.gov (United States)

    2012-08-14

    ... authorized by 49 U.S.C. 5309(b), as amended by Section 3011 of the Safe, Affordable, Flexible, Efficient... Livability Initiatives (77 FR 6178). The NOFA explained the requirements and procedures for eligible... facilities, bus-related equipment, and transit asset management systems. The FY 2012 Bus...

  6. American Fuel Cell Bus Project Evaluation. Second Report

    Energy Technology Data Exchange (ETDEWEB)

    Eudy, Leslie [National Renewable Energy Lab. (NREL), Golden, CO (United States); Post, Matthew [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2015-09-01

    This report presents results of the American Fuel Cell Bus (AFCB) Project, a demonstration of fuel cell electric buses operating in the Coachella Valley area of California. The prototype AFCB was developed as part of the Federal Transit Administration's (FTA's) National Fuel Cell Bus Program. Through the non-profit consortia CALSTART, a team led by SunLine Transit Agency and BAE Systems developed a new fuel cell electric bus for demonstration. SunLine added two more AFCBs to its fleet in 2014 and another in 2015. FTA and the AFCB project team are collaborating with the U.S. Department of Energy (DOE) and DOE's National Renewable Energy Laboratory to evaluate the buses in revenue service. This report summarizes the performance results for the buses through June 2015.

  7. FUEL CELL BUS DEMONSTRATION IN MEXICO CITY

    Science.gov (United States)

    The report discusses the performance of a cull-size, zero-emission, Proton Exchange Membrane (PEM) fuel-cell-powered transit bus in the atmospheric environment of Mexico City. To address the air quality problems caused by vehicle emissions in Mexico City, a seminar on clean vehic...

  8. Virginia School Bus Driver Training: Does Training Program Adequacy Affect school Bus Accident Rates?

    OpenAIRE

    Crews, James O

    1997-01-01

    Analysis of data provided by the Virginia Departments of Motor Vehicles, Transportation, and Education all show school buses as having a significantly higher number of accidents per hundred million miles of travel than other forms of transportation. Such statistics are alarming and formal study of school bus accident factors has been limited. The purposes of this study were to (a) establish the adequacy of the school bus driver training programs of Local Education Agencies(LEAs...

  9. Brazilian hybrid electric fuel cell bus

    Energy Technology Data Exchange (ETDEWEB)

    Miranda, P.E.V.; Carreira, E.S. [Coppe-Federal Univ. of Rio de Janeiro (Brazil). Hydrogen Lab.

    2010-07-01

    The first prototype of a hybrid electric fuel cell bus developed with Brazilian technology is unveiled. It is a 12 m urban-type, low-floor, air-conditioned bus that possesses three doors, air suspension, 29 seats and reversible wheelchair site. The bus body was built based on a double-deck type monoblock vehicle that is able to sustain important load on its roof. This allowed positioning of the type 3 hydrogen tanks and the low weight traction batteries on the roof of the vehicles without dynamic stabilization problems. A novel hybrid energy configuration was designed in such a way that the low-power (77 kWe) fuel cell works on steady-state operation mode, not responding directly to the traction motor load demand. The rate of kinetic energy regeneration upon breaking was optimized by the use of an electric hybrid system with predominance of batteries and also by utilizing supercapacitors. The electric-electronic devices and the security control softwares for the auxiliary and traction systems were developed in-house. The innovative hybrid-electric traction system configuration led to the possibility to decrease the fuel cell power, with positive impact on weight and system volume reduction, as well as to significantly decrease the hydrogen consumption. (orig.)

  10. The high speed bus technology development program

    Science.gov (United States)

    Ludvigson, M. T.; Modrow, M. B.; Goldman, P. C.

    The current development status of a high-speed data bus to link MIL-STD-1750A computers in avionics applications is reviewed and illustrated with diagrams and photographs. The bus requirements include data rate 50 Mb/s, a linear token-passing scheme permitting both electronic and fiber-optic implementation, up to 64-terminal capacity, maximum terminal separation 300 ft, latency control via token-rotation-timer priority, self-test and bus-loop test capability, and automatic clock synchronization. The design concept and performance of a breadboard wire bus tested in July 1986 are discussed in detail, with particular attention to the redundancy manager, the output controller, the input controller, the ringmaster topology manager, and typical initial-placement problems.

  11. Connecticut Transit (CTTRANSIT) Fuel Cell Transit Bus: Preliminary Evaluation Results

    Energy Technology Data Exchange (ETDEWEB)

    Chandler, K.; Eudy, L.

    2008-10-01

    This report provides preliminary results from a National Renewable Energy Laboratory evaluation of a protoptye fuel cell transit bus operating at Connecticut Transit in Hartford. Included are descriptions of the planned fuel cell bus demonstration and equipment; early results and agency experience are also provided.

  12. Black silicon solar cells with black bus-bar strings

    DEFF Research Database (Denmark)

    Davidsen, Rasmus Schmidt; Tang, Peter Torben; Mizushima, Io;

    2016-01-01

    We present the combination of black silicon texturing and blackened bus-bar strings as a potential method for obtaining all-black solar panels, while using conventional, front-contacted solar cells. Black silicon was realized by maskless reactive ion etching resulting in total, average reflectance...... below 0.5% across a 156x156 mm2 silicon wafer. Four different methods to obtain blackened bus-bar strings were compared with respect to reflectance, and two of these methods (i.e., oxidized copper and etched solder) were used to fabricate functional allblack solar 9-cell panels. The black bus-bars (e.......g., by oxidized copper) have a reflectance below 3% in the entire visible wavelength range. The combination of black silicon cells and blackened bus-bars results in aesthetic, all-black panels based on conventional, front-contacted solar cells without compromising efficiency....

  13. Real life testing of a Hybrid PEM Fuel Cell Bus

    Science.gov (United States)

    Folkesson, Anders; Andersson, Christian; Alvfors, Per; Alaküla, Mats; Overgaard, Lars

    Fuel cells produce low quantities of local emissions, if any, and are therefore one of the most promising alternatives to internal combustion engines as the main power source in future vehicles. It is likely that urban buses will be among the first commercial applications for fuel cells in vehicles. This is due to the fact that urban buses are highly visible for the public, they contribute significantly to air pollution in urban areas, they have small limitations in weight and volume and fuelling is handled via a centralised infrastructure. Results and experiences from real life measurements of energy flows in a Scania Hybrid PEM Fuel Cell Concept Bus are presented in this paper. The tests consist of measurements during several standard duty cycles. The efficiency of the fuel cell system and of the complete vehicle are presented and discussed. The net efficiency of the fuel cell system was approximately 40% and the fuel consumption of the concept bus is between 42 and 48% lower compared to a standard Scania bus. Energy recovery by regenerative braking saves up 28% energy. Bus subsystems such as the pneumatic system for door opening, suspension and brakes, the hydraulic power steering, the 24 V grid, the water pump and the cooling fans consume approximately 7% of the energy in the fuel input or 17% of the net power output from the fuel cell system. The bus was built by a number of companies in a project partly financed by the European Commission's Joule programme. The comprehensive testing is partly financed by the Swedish programme "Den Gröna Bilen" (The Green Car). A 50 kW el fuel cell system is the power source and a high voltage battery pack works as an energy buffer and power booster. The fuel, compressed hydrogen, is stored in two high-pressure stainless steel vessels mounted on the roof of the bus. The bus has a series hybrid electric driveline with wheel hub motors with a maximum power of 100 kW. Hybrid Fuel Cell Buses have a big potential, but there are

  14. SunLine Transit Agency Advanced Technology Fuel Cell Bus Evaluation: First Results Report

    Energy Technology Data Exchange (ETDEWEB)

    Eudy, L.; Chandler, K.

    2011-03-01

    This report describes operations at SunLine Transit Agency for their newest prototype fuel cell bus and five compressed natural gas (CNG) buses. In May 2010, SunLine began operating its sixth-generation hydrogen fueled bus, an Advanced Technology (AT) fuel cell bus that incorporates the latest design improvements to reduce weight and increase reliability and performance. The agency is collaborating with the U.S. Department of Energy's (DOE) National Renewable Energy Laboratory (NREL) to evaluate the bus in revenue service. This report provides the early data results and implementation experience of the AT fuel cell bus since it was placed in service.

  15. City of Chula Vista hydrogen fuel cell bus demonstration project

    Energy Technology Data Exchange (ETDEWEB)

    Gustafson, B.; Bamberger, B.

    1996-10-01

    Hydrogen as an energy carrier and fuel has potential for various uses including electricity, commercial, residential, transportation, and industrial. It is an energy carrier that can be produced from a variety of primary sources and potentially can accomplish these various uses while significantly reducing pollution by substituting for or reducing the use of fossil fuels. One of the most immediate and potentially viable roles for hydrogen as an energy carrier will be its use as a transportation fuel, especially in densely populated urban areas where automotive emissions contribute significantly to air pollution. The Department of Energy`s commitment to research and development of hydrogen as an alternative fuel, and California`s Zero Emission Vehicle (ZEV) requirements, both provide the impetus and favorable circumstance for demonstrating hydrogen as a transportation fuel on an urban bus system. The purpose of this project is to demonstrate the feasibility of using solid polymer fuel cells in a hydrogen-powered electric drive system for an urban transit bus application. Fuel cell buses use hydrogen fuel and oxygen from the air to produce electrical power with the only byproduct being pure water. Proton Exchange Membrane (PEM) fuel cells are proposed for this project. Current evidence suggests that fuel cells, which rely on hydrogen and a process known as proton exchange to generate their power, appear to have an infinite life span. All exhaust pollution is completely eliminated, resulting in a Zero Emission Vehicle (ZEV). An urban bus system offers the potential for developing a market for the production of hydrogen propulsion technology due to extensive vehicular use in densely populated areas experiencing pollution from numerous sources, and because the central garaging facilities or the bus system facilitates fueling and maintenance functions.

  16. BC Transit Fuel Cell Bus Project: Evaluation Results Report

    Energy Technology Data Exchange (ETDEWEB)

    Eudy, L.; Post, M.

    2014-02-01

    This report evaluates a fuel cell electric bus demonstration led by British Columbia Transit (BC Transit) in Whistler, Canada. BC Transit is collaborating with the California Air Resources Board and the U.S. Department of Energy's National Renewable Energy Laboratory to evaluate the buses in revenue service. This evaluation report covers two years of revenue service data on the buses from April 2011 through March 2013.

  17. SunLine Transit Agency Advanced Technology Fuel Cell Bus Evaluation: Fourth Results Report

    Energy Technology Data Exchange (ETDEWEB)

    Eudy, L.; Chandler, K.

    2013-01-01

    SunLine Transit Agency, which provides public transit services to the Coachella Valley area of California, has demonstrated hydrogen and fuel cell bus technologies for more than 10 years. In May 2010, SunLine began demonstrating the advanced technology (AT) fuel cell bus with a hybrid electric propulsion system, fuel cell power system, and lithium-based hybrid batteries. This report describes operations at SunLine for the AT fuel cell bus and five compressed natural gas buses. The U.S. Department of Energy's National Renewable Energy Laboratory (NREL) is working with SunLine to evaluate the bus in real-world service to document the results and help determine the progress toward technology readiness. NREL has previously published three reports documenting the operation of the fuel cell bus in service. This report provides a summary of the results with a focus on the bus operation from February 2012 through November 2012.

  18. BC Transit Fuel Cell Bus Project Evaluation Results: Second Report

    Energy Technology Data Exchange (ETDEWEB)

    Eudy, L.; Post, M.

    2014-09-01

    Second report evaluating a fuel cell electric bus (FCEB) demonstration led by British Columbia Transit (BC Transit) in Whistler, Canada. BC Transit is collaborating with the California Air Resources Board and the U.S. Department of Energy's National Renewable Energy Laboratory to evaluate the buses in revenue service. NREL published its first report on the demonstration in February 2014. This report is an update to the previous report; it covers 3 full years of revenue service data on the buses from April 2011 through March 2014 and focuses on the final experiences and lessons learned.

  19. SunLine Transit Agency Advanced Technology Fuel Cell Bus Evaluation: Third Results Reports

    Energy Technology Data Exchange (ETDEWEB)

    Eudy, L.; Chandler, K.

    2012-05-01

    This report describes operations at SunLine Transit Agency for their newest prototype fuel cell bus and five compressed natural gas (CNG) buses. In May 2010, SunLine began operating its sixth-generation hydrogen fueled bus, an Advanced Technology (AT) fuel cell bus that incorporates the latest design improvements to reduce weight and increase reliability and performance. The agency is collaborating with the U.S. Department of Energy's (DOE) National Renewable Energy Laboratory (NREL) to evaluate the bus in revenue service. NREL has previously published two reports documenting the operation of the fuel cell bus in service. This report provides a summary of the results with a focus on the bus operation from July 2011 through January 2012.

  20. SunLine Transit Agency Advanced Technology Fuel Cell Bus Evaluation: Second Results Report and Appendices

    Energy Technology Data Exchange (ETDEWEB)

    Eudy, L.; Chandler, K.

    2011-10-01

    This report describes operations at SunLine Transit Agency for their newest prototype fuel cell bus and five compressed natural gas (CNG) buses. In May 2010, SunLine began operating its sixth-generation hydrogen fueled bus, an Advanced Technology (AT) fuel cell bus that incorporates the latest design improvements to reduce weight and increase reliability and performance. The agency is collaborating with the U.S. Department of Energy's (DOE) National Renewable Energy Laboratory (NREL) to evaluate the bus in revenue service. This is the second results report for the AT fuel cell bus since it was placed in service, and it focuses on the newest data analysis and lessons learned since the previous report. The appendices, referenced in the main report, provide the full background for the evaluation. They will be updated as new information is collected but will contain the original background material from the first report.

  1. Connecticut Transit (CTTRANSIT) Fuel Cell Transit Bus: Third Evaluation Report and Appendices

    Energy Technology Data Exchange (ETDEWEB)

    Chandler, K.; Eudy, L.

    2010-01-01

    This report describes operations at Connecticut Transit (CTTRANSIT) in Hartford for one prototype fuel cell bus and three new diesel buses operating from the same location. The prototype fuel cell bus was manufactured by Van Hool and ISE Corp. and features an electric hybrid drive system with a UTC Power PureMotion 120 Fuel Cell Power System and ZEBRA batteries for energy storage. The fuel cell bus started operation in April 2007, and evaluation results through October 2009 are provided in this report.

  2. 75 FR 5847 - Section 5309 Bus and Bus Facilities Livability Initiative and Urban Circulator Program Grants

    Science.gov (United States)

    2010-02-04

    ... (SAFETEA-LU), Public Law 109-59, August 10, 2005. The Urban Circulator Program is funded using $130 million..., Accountable, Flexible, Efficient, Transportation Equity Act: A Legacy for Users (SAFETEA-LU), Public Law 109-59, August 10, 2005. DATES: This Notice will extend the submittal date for proposals of...

  3. Effect of Educational Program to Decrease Substance Abuse among Suburban Bus Drivers Based on Theory of Planned Behavior

    OpenAIRE

    Moeini, B.; S. Bashirian; A. Moghimbeigi; V. Kafami; A.A. Mousali

    2015-01-01

    Introduction & Objective: Driving under the influence of drugs is considered a social pathology that has adverse effects on a society. This study aimed to investigate the effect of substance abuse educational program among the bus drivers on the basis of the theory of planned be-havior. Materials & Methods: This quasi-experimental study was conducted on 80 suburban bus drivers working at Hamadan transportation terminal. The bus drivers were randomly divided in two equal groups (intervention a...

  4. 77 FR 5295 - Over-the-Road Bus Accessibility Program Announcement of Project Selections

    Science.gov (United States)

    2012-02-02

    ... by Section 3038 of the Transportation Equity Act for the 21st Century (TEA-21). The OTRB... FTA's Transportation Electronic Awards Management System (TEAM) for the projects identified in Tables... TRANSPORTATION Federal Transit Administration Over-the-Road Bus Accessibility Program Announcement of...

  5. Impact of a walking school bus program on children's active commuting to school and physical activity

    Science.gov (United States)

    Walking School Buses (WSB) are groups of students, led to and from school by adults, in which students are picked up at designated "bus stops". The impact of WSB programs on students' active commuting to school (walking/cycling to school, ACS), and moderate-to vigorous-physical activity (MVPA) has n...

  6. Savannah River bus project

    Energy Technology Data Exchange (ETDEWEB)

    Summers, W.A. [Westinghouse Savannah River Co., Aiken, SC (United States)

    1998-08-01

    The H2Fuel Bus is the world`s first hybrid hydrogen electric transit bus. It was developed through a public/private partnership involving several leading technology and industrial organizations in the Southeast, with primary funding and program management provided by the Department of Energy. The primary goals of the project are to gain valuable information on the technical readiness and economic viability of hydrogen buses and to enhance the public awareness and acceptance of emerging hydrogen technologies. The bus has been operated by the transit agency in Augusta, Georgia since April, 1997. It employs a hybrid IC engine/battery/electric drive system, with onboard hydrogen fuel storage based on the use of metal hydrides. Initial operating results have demonstrated an overall energy efficiency (miles per Btu) of twice that of a similar diesel-fueled bus and an operating range twice that of an all-battery powered electric bus. Tailpipe emissions are negligible, with NOx less than 0.2 ppm. Permitting, liability and insurance issues were addressed on the basis of extensive risk assessment and safety analyses, with the inherent safety characteristic of metal hydride storage playing a major role in minimizing these concerns. Future plans for the bus include continued transit operation and use as a national testbed, with potential modifications to demonstrate other hydrogen technologies, including fuel cells.

  7. Fuel cell propulsion for urban duty vehicles: Bavarian fuel cell bus project

    International Nuclear Information System (INIS)

    Following a feasibility study and a detailed specification phase, the realization of a fuel cell city bus prototype was started in autumn 1996. The project is a joint development effort of Siemens, MAN and Linde, which receives a 50 % funding by the Bavarian State Ministry for Economic Affairs, Transport and Technology (BStMWVT) in the context of the Hydrogen Initiative Bavaria. An MAN low-floor bus will be equipped with the components for a fuel cell drive system. The PEM fuel cell is developed by the power generation division of Siemens. Four fuel cell modules deliver a total electrical output of 120 kW to the two electric motors, which are linked by a summation gearbox by the Siemens Transportation Systems Division. MAN Technologie AG is responsible for the compressed hydrogen storage system allowing for a driving range of more than 250 km, while Linde AG takes care of the hydrogen periphery and delivers the hydrogen for the test operation scheduled for the beginning of the year 2000. Project coordination is done by Ludwig-Boelkow System-technik GmbH. The project is divided into four phases. The conceptual design phase is scheduled to last until the end of 1997. The partly overlapping system integration phase will end in the first quarter of 1999. The subsequent test and commissioning phase will prepare the test operation at the beginning of 2000 with a bus operator yet to be defined. (author)

  8. “Prezewody” program for capacitance and inductance determination of can-bus transmission lines

    OpenAIRE

    Kalita, W.; Kamuda, K.; Sabat, W,; Wisz, B.

    2004-01-01

    The describing of the computer program which allows to determine residual parameters of the cable system with cylindrical section has been included in the paper. The wire capacitance and inductance, whice are used in data transmission systems (i.e. CAN-bus). have a big influence on parameters of the transmission line. The knowing of these parameters allows to select the optimal conditions of the such systems from the point view of transmission quality and electromagnetic compatibility.

  9. Ansaldo programs on fuel cell vehicles

    Energy Technology Data Exchange (ETDEWEB)

    Marcenaro, B.G.; Federici, F. [Ansaldo Ricerche Srl, Genova (Italy)

    1996-12-31

    The growth in traffic and the importance of maintaining a stable ecology at the global scale, particularly with regard to atmospheric pollution, raises the necessity to realize a new generation of vehicles which are more efficient, more economical and compatible with the environment. At European level, the Car of Tomorrow task force has identified fuel cells as a promising alternative propulsion system. Ansaldo Ricerche has been involved in the development of fuel cell vehicles since the early nineties. Current ongoing programs relates to: (1) Fuel cell bus demonstrator (EQHEPP BUS) Test in 1996 (2) Fuel cell boat demonstrator (EQHHPP BOAT) Test in 1997 (3) Fuel cell passenger car prototype (FEVER) Test in 1997 (4) 2nd generation Fuel cell bus (FCBUS) 1996-1999 (5) 2nd generation Fuel cell passenger car (HYDRO-GEN) 1996-1999.

  10. Research, development and demonstration of a fuel cell/battery powered bus system. Phase 1, Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1990-02-28

    Purpose of the Phase I effort was to demonstrate feasibility of the fuel cell/battery system for powering a small bus (under 30 ft or 9 m) on an urban bus route. A brassboard powerplant was specified, designed, fabricated, and tested to demonstrate feasibility in the laboratory. The proof-of-concept bus, with a powerplant scaled up from the brassboard, will be demonstrated under Phase II.

  11. Life-cycle assessment of diesel, natural gas and hydrogen fuel cell bus transportation systems

    Science.gov (United States)

    Ally, Jamie; Pryor, Trevor

    The Sustainable Transport Energy Programme (STEP) is an initiative of the Government of Western Australia, to explore hydrogen fuel cell technology as an alternative to the existing diesel and natural gas public transit infrastructure in Perth. This project includes three buses manufactured by DaimlerChrysler with Ballard fuel cell power sources operating in regular service alongside the existing natural gas and diesel bus fleets. The life-cycle assessment (LCA) of the fuel cell bus trial in Perth determines the overall environmental footprint and energy demand by studying all phases of the complete transportation system, including the hydrogen infrastructure, bus manufacturing, operation, and end-of-life disposal. The LCAs of the existing diesel and natural gas transportation systems are developed in parallel. The findings show that the trial is competitive with the diesel and natural gas bus systems in terms of global warming potential and eutrophication. Emissions that contribute to acidification and photochemical ozone are greater for the fuel cell buses. Scenario analysis quantifies the improvements that can be expected in future generations of fuel cell vehicles and shows that a reduction of greater than 50% is achievable in the greenhouse gas, photochemical ozone creation and primary energy demand impact categories.

  12. Connecticut Transit (CTTRANSIT) Fuel Cell Transit Bus: Second Evaluation Report and Appendices

    Energy Technology Data Exchange (ETDEWEB)

    Chandler, K.; Eudy, L.

    2009-05-01

    This report describes operations at Connecticut Transit (CTTRANSIT) in Hartford for one prototype fuel cell bus and three new diesel buses operating from the same location. The evaluation period in this report (January 2008 through February 2009) has been chosen to coincide with a UTC Power propulsion system changeout that occurred on January 15, 2008.

  13. SunLine Transit Agency Fuel Cell Transit Bus: Fifth Evaluation Report (Report and Appendices)

    Energy Technology Data Exchange (ETDEWEB)

    Eudy, L.; Chandler, K.

    2009-08-01

    This report describes operations at SunLine Transit Agency for a prototype fuel cell bus and five compressed natural gas (CNG) buses. This is the fifth evaluation report for this site, and it describes results and experiences from October 2008 through June 2009. These results are an addition to those provided in the previous four evaluation reports.

  14. SunLine Transit Agency Fuel Cell Transit Bus: Fourth Evaluation Report (Report and Appendices)

    Energy Technology Data Exchange (ETDEWEB)

    Chandler, K.; Eudy, L.

    2009-01-01

    This report describes operations at SunLine Transit Agency for a prototype fuel cell bus and five new compressed natural gas (CNG) buses. This is the fourth evaluation report for this site, and it describes results and experiences from April 2008 through October 2008. These results are an addition to those provided in the previous three evaluation reports.

  15. Grid-Optimization Program for Photovoltaic Cells

    Science.gov (United States)

    Daniel, R. E.; Lee, T. S.

    1986-01-01

    CELLOPT program developed to assist in designing grid pattern of current-conducting material on photovoltaic cell. Analyzes parasitic resistance losses and shadow loss associated with metallized grid pattern on both round and rectangular solar cells. Though performs sensitivity studies, used primarily to optimize grid design in terms of bus bar and grid lines by minimizing power loss. CELLOPT written in APL.

  16. Selection of a fiber optic data bus for the FLASH program

    Science.gov (United States)

    Green, Samuel I.

    1995-05-01

    The Fly-by-Light Advanced Systems Hardware (FLASH) program is developing Fly-by-Light technologies for flight control and vehicle management of military and commercial aircraft. Fiber optics offers greatly improved data transfer rate, very low susceptibility to electromagnetic interference (EMI), lower on-board weight, and lower operating and maintenance costs. FLASH will result in demonstrations needed to gain confidence in using Fly-by-Light for flight control and vehicle management. This paper reviews the requirements and the trade study leading to selection of the dual-rate 1773A fiber optic data bus to interconnect fly-by-light advanced system hardware.

  17. Programming WCF Services Mastering WCF and the Azure AppFabric Service Bus

    CERN Document Server

    Lowy, Juval

    2010-01-01

    Programming WCF Services is the authoritative, bestselling guide to Microsoft's unified platform for developing modern service-oriented applications on Windows. Hailed as the definitive treatment of WCF, this book provides unique insight, rather than documentation, to help you learn the topics and skills you need for building WCF-based applications that are maintainable, extensible, and reusable. Author Juval Löwy -- one of the world's top .NET experts -- revised this edition to include the newest productivity-enhancing features of .NET Framework 4 and the Azure AppFabric Service Bus, as wel

  18. Bluetooth wireless monitoring, diagnosis and calibration interface for control system of fuel cell bus in Olympic demonstration

    Energy Technology Data Exchange (ETDEWEB)

    Hua, Jianfeng; Lin, Xinfan; Xu, Liangfei; Li, Jianqiu; Ouyang, Minggao [Tsinghua University, State Key Laboratory of Automotive Safety and Energy, Beijing100084 (China)

    2009-01-15

    With the worldwide deterioration of the natural environment and the fossil fuel crisis, the possible commercialization of fuel cell vehicles has become a hot topic. In July 2008, Beijing started a clean public transportation plan for the 29th Olympic games. Three fuel cell city buses and 497 other low-emission vehicles are now serving the Olympic core area and Beijing urban areas. The fuel cell buses will operate along a fixed bus line for 1 year as a public demonstration of green energy vehicles. Due to the specialized nature of fuel cell engines and electrified power-train systems, measurement, monitoring and calibration devices are indispensable. Based on the latest Bluetooth wireless technology, a novel Bluetooth universal data interface was developed for the control system of the fuel cell city bus. On this platform, a series of wireless portable control auxiliary systems have been implemented, including wireless calibration, a monitoring system and an in-system programming platform, all of which are ensuring normal operation of the fuel cell buses used in the demonstration. (author)

  19. Bluetooth wireless monitoring, diagnosis and calibration interface for control system of fuel cell bus in Olympic demonstration

    Science.gov (United States)

    Hua, Jianfeng; Lin, Xinfan; Xu, Liangfei; Li, Jianqiu; Ouyang, Minggao

    With the worldwide deterioration of the natural environment and the fossil fuel crisis, the possible commercialization of fuel cell vehicles has become a hot topic. In July 2008, Beijing started a clean public transportation plan for the 29th Olympic games. Three fuel cell city buses and 497 other low-emission vehicles are now serving the Olympic core area and Beijing urban areas. The fuel cell buses will operate along a fixed bus line for 1 year as a public demonstration of green energy vehicles. Due to the specialized nature of fuel cell engines and electrified power-train systems, measurement, monitoring and calibration devices are indispensable. Based on the latest Bluetooth wireless technology, a novel Bluetooth universal data interface was developed for the control system of the fuel cell city bus. On this platform, a series of wireless portable control auxiliary systems have been implemented, including wireless calibration, a monitoring system and an in-system programming platform, all of which are ensuring normal operation of the fuel cell buses used in the demonstration.

  20. High-Speed Ring Bus

    Science.gov (United States)

    Wysocky, Terry; Kopf, Edward, Jr.; Katanyoutananti, Sunant; Steiner, Carl; Balian, Harry

    2010-01-01

    The high-speed ring bus at the Jet Propulsion Laboratory (JPL) allows for future growth trends in spacecraft seen with future scientific missions. This innovation constitutes an enhancement of the 1393 bus as documented in the Institute of Electrical and Electronics Engineers (IEEE) 1393-1999 standard for a spaceborne fiber-optic data bus. It allows for high-bandwidth and time synchronization of all nodes on the ring. The JPL ring bus allows for interconnection of active units with autonomous operation and increased fault handling at high bandwidths. It minimizes the flight software interface with an intelligent physical layer design that has few states to manage as well as simplified testability. The design will soon be documented in the AS-1393 standard (Serial Hi-Rel Ring Network for Aerospace Applications). The framework is designed for "Class A" spacecraft operation and provides redundant data paths. It is based on "fault containment regions" and "redundant functional regions (RFR)" and has a method for allocating cables that completely supports the redundancy in spacecraft design, allowing for a complete RFR to fail. This design reduces the mass of the bus by incorporating both the Control Unit and the Data Unit in the same hardware. The standard uses ATM (asynchronous transfer mode) packets, standardized by ITU-T, ANSI, ETSI, and the ATM Forum. The IEEE-1393 standard uses the UNI form of the packet and provides no protection for the data portion of the cell. The JPL design adds optional formatting to this data portion. This design extends fault protection beyond that of the interconnect. This includes adding protection to the data portion that is contained within the Bus Interface Units (BIUs) and by adding to the signal interface between the Data Host and the JPL 1393 Ring Bus. Data transfer on the ring bus does not involve a master or initiator. Following bus protocol, any BIU may transmit data on the ring whenever it has data received from its host. There

  1. Support and power plant documentation for the gas turbine powered bus demonstration program

    Science.gov (United States)

    Nigro, D. N.; Stewart, R. G.; Apple, S. A.

    1982-01-01

    The operational experience obtained for the GT404-4 gas turbine engines in the intercity and intracity Bus Demonstration Programs is described for the period January 1980 through September 1981. Support for the engines and automatic transmissions involved in this program provided engineering and field service, spare parts and tools, training, and factory overhauls. the Greyhound (intercity) coaches accumulated 183,054 mi (294,595 km) and 5154 hr of total operation. The Baltimore Transit (intracity) coaches accumulated 40,567 mi (65,285 km) and 1840 hr of total operation. In service, the turbine powered Greyhound and Transit coaches achieved approximately 25% and 40% lower fuel mileage, respectively, than did the production diesel powered coaches. The gas turbine engine will require the advanced ceramic development currently being sponsored by the DOE and NASA to achieve fuel economy equivalent not only to that of today's diesel engines but also to the projected fuel economy of the advanced diesel engines of the 1990s. Sufficient experience was not achieved with the coaches prior to the start of service to identify and eliminate many of the problems associated with the startup of new equipment. Because of these problems, the mean miles between incident were unacceptably low. The future gas turbine system should be developed sufficiently to establish satisfactory durability prior to evaluation in revenue service. Commercialization of the gas turbine bus engine remains a viable goal for the future.

  2. Impact of a walking school bus program on children’s active commuting to school and physical activity

    Science.gov (United States)

    The Walking School Bus (WSB) pilot program was evaluated to determine the impact on student’s Active Commuting to School (ACS) and moderate-to vigorous- physical activity (MVPA). We conducted a randomized controlled trial in 8 low income, elementary schools in Houston, TX, USA. Students (n=149) wer...

  3. Optimal vehicle control strategy of a fuel cell/battery hybrid city bus

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Liangfei; Li, Jianqiu; Hua, Jianfeng; Li, Xiangjun; Ouyang, Minggao [State Key Laboratory of Automotive Safety and Energy, Tsinghua University, Beijing 100084 (China)

    2009-09-15

    In this article, an optimal vehicle control strategy based on a time-triggered controller area network (TTCAN) system for a polymer electrolyte membrane (PEM) fuel cell/nickel-metal hydride (Ni-MH) battery powered city bus is presented. Aiming at improving the fuel economy of the city bus, the control strategy comprises an equivalent consumption minimization strategy (ECMS) and a braking energy regeneration strategy (BERS). On the basis of the introduction of a battery equivalent hydrogen consumption model incorporating a charge-sustaining coefficient, an analytical solution to the equivalent consumption minimization problem is given. The proposed strategy has been applied in several city buses for the Beijing Olympic Games of 2008. Results of the ''China city bus typical cycle'' testing show that, the ECMS and the BERS lowered hydrogen consumption by 2.5% and 15.3% respectively, compared with a rule-based strategy. The BERS contributes much more than the ECMS to the fuel economy, because the fuel cell system does not leave much room for the optimal algorithm in improving the efficiency. (author)

  4. Development of a PEM Fuel Cell City Bus with a Hierarchical Control System

    Directory of Open Access Journals (Sweden)

    Siliang Cheng

    2016-05-01

    Full Text Available The polymer electrolyte membrane (PEM fuel cell system is considered to be an ideal alternative for the internal combustion engine, especially when used on a city bus. Hybrid buses with fuel cell systems and energy storage systems are now undergoing transit service demonstrations worldwide. A hybrid PEM fuel cell city bus with a hierarchical control system is studied in this paper. Firstly, the powertrain and hierarchical control structure is introduced. Secondly, the vehicle control strategy including start-stop strategy, energy management strategy, and fuel cell control strategy, including the hydrogen system and air system control strategies, are described in detail. Finally, the performance of the fuel cell was analyzed based on road test data. Results showed that the different subsystems were well-coordinated. Each component functioned in concert in order to ensure that both safety and speed requirements were satisfied. The output current of the fuel cell system changed slowly and the output voltage was limited to a certain range, thereby enhancing durability of the fuel cell. Furthermore, the economic performance was optimized by avoiding low load conditions.

  5. BUS 501 Str course tutorial / uophelp

    OpenAIRE

    uophel

    2015-01-01

    For more course tutorials visit www.uophelp.com     BUS 501 Week 3 Assignment 1 The Independent Government Cost Estimate and the Statement of Work (Str Course) BUS 501 Week 4 Assignment 2 Types of Contracts and Performance-Based Acquisition (Str Course) BUS 501 Week 7 Assignment 3 Small Business Program and Source Selection Plans (Str Course) BUS 501 Assignment 4 Technical and Cost or Price Evaluations and Price Reasonableness (Str Course) BUS 501 Wee...

  6. BUS 650 UOP Material - bus650dotcom

    OpenAIRE

    lucky108

    2015-01-01

    For more course tutorials visit www.bus650.com BUS 650 Week 1 DQ 1 The Role of Financial Management in a Firm BUS 650 Week 1 DQ 2 Short Term or Long Term View BUS 650 Week 1 Financial Management Challenges BUS 650 Week 2 DQ 1 Initial Investment BUS 650 Week 2 DQ 2 Managing Earnings BUS 650 Week 2 Return on Investment Education Funding BUS 650 Week 3 DQ 1 GAAP vs. IFRS BUS 650 Week 3 DQ 2 Capital Rationing BUS 650 Week 3 Journal Capital Budgeting BUS 650 Week 3 Management of Working Capital Ca...

  7. Effect of Educational Program to Decrease Substance Abuse among Suburban Bus Drivers Based on Theory of Planned Behavior

    Directory of Open Access Journals (Sweden)

    B. Moeini

    2015-01-01

    Full Text Available Introduction & Objective: Driving under the influence of drugs is considered a social pathology that has adverse effects on a society. This study aimed to investigate the effect of substance abuse educational program among the bus drivers on the basis of the theory of planned be-havior. Materials & Methods: This quasi-experimental study was conducted on 80 suburban bus drivers working at Hamadan transportation terminal. The bus drivers were randomly divided in two equal groups (intervention and control. Intervention program design was implemented after diagnostic evaluation. The effect of educational intervention on behavior was assessed two months after the last training session. SPSS -16 was employed for data analysis. Results: After the educational intervention, the average rates of the constructs of the theory of planned behavior in the intervention group significantly increased but these changes were not significant in the control group: attitude (t=9.53, P=0.000, subjective Norms (t=9.59, P=0.000, perceived behavioral control (t=-4.14, P =0.000. Also, behavioral intention to substance abuse avoidance and current behavior for substance abuse significantly decreased in the intervention group as compared to the control group (P<0.05. Behavioral intention and current behavior in the intervention group subsided from 15 and 12 people before the educational intervention to 3 and 0 people at the end of the educational program, respec-tively. Conclusion: The results showed that using the theory of planned behavior along with the train-ing skills strategies to resist drug abuse has a significant impact to create a psychiatric immu-nization and substance refusal in drivers. (Sci J Hamadan Univ Med Sci 2015; 21 (4:330-340

  8. Texas Hydrogen Highway Fuel Cell Hybrid Bus and Fueling Infrastructure Technology Showcase - Final Scientific/Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Hitchcock, David

    2012-06-29

    The Texas Hydrogen Highway project has showcased a hydrogen fuel cell transit bus and hydrogen fueling infrastructure that was designed and built through previous support from various public and private sector entities. The aim of this project has been to increase awareness among transit agencies and other public entities on these transportation technologies, and to place such technologies into commercial applications, such as a public transit agency. The initial project concept developed in 2004 was to show that a skid-mounted, fully-integrated, factory-built and tested hydrogen fueling station could be used to simplify the design, and lower the cost of fueling infrastructure for fuel cell vehicles. The approach was to design, engineer, build, and test the integrated fueling station at the factory then install it at a site that offered educational and technical resources and provide an opportunity to showcase both the fueling station and advanced hydrogen vehicles. The two primary technology components include: Hydrogen Fueling Station: The hydrogen fueling infrastructure was designed and built by Gas Technology Institute primarily through a funding grant from the Texas Commission on Environmental Quality. It includes hydrogen production, clean-up, compression, storage, and dispensing. The station consists of a steam methane reformer, gas clean-up system, gas compressor and 48 kilograms of hydrogen storage capacity for dispensing at 5000 psig. The station is skid-mounted for easy installation and can be relocated if needed. It includes a dispenser that is designed to provide temperaturecompensated fills using a control algorithm. The total station daily capacity is approximately 50 kilograms. Fuel Cell Bus: The transit passenger bus built by Ebus, a company located in Downey, CA, was commissioned and acquired by GTI prior to this project. It is a fuel cell plug-in hybrid electric vehicle which is ADA compliant, has air conditioning sufficient for Texas operations

  9. Program Guide for Diesel Engine Mechanics 8742000 (IN47.060500) and Heavy Duty Truck and Bus Mechanics DIM0991 (IN47.060501).

    Science.gov (United States)

    University of South Florida, Tampa. Coll. of Education.

    This competency-based program guide provides course content information and procedures for secondary schools, postsecondary vocational schools, and community colleges in Florida that conduct programs in diesel engine mechanics and heavy duty truck and bus mechanics. The first section is on legal authority, which applies to all vocational education…

  10. Standard satellite data bus initiative

    Science.gov (United States)

    Spinney, Timothy; Yousef, Hassan

    The USAF Space Technology Center manages programs to reduce satellite costs through the appropriate use of microelectronics standardization. Ongoing programs such as the Standard Spacecraft Memory Module and Generic VHSIC Spaceborne Computer have provided an insight into the value of standardization and led to an initiative to coordinate microelectronics development around a standard satellite data bus, which should reduce costs by eliminating program- and contractor-unique interfaces, increasing production runs, and developing generic test equipment. Current efforts focus on the satellite housekeeping functions, and it is expected that the mission payload would also use this data bus. Based on existing housekeeping data-traffic requirements, several candidates have been identified for the standard data bus. The two candidates selected for further work are the ANSI X3T9.5 data bus and the linear token-passing data bus being proposed as part of the Advanced Tactical Fighter effort.

  11. BUS 372 ASH Material - bus372dotcom

    OpenAIRE

    lucky108

    2015-01-01

    For more course tutorials visit www.bus372.com       BUS 372 Week 1 DQ 1 The Role of Unionization (Ash Course) BUS 372 Week 1 DQ 2 Meeting Member Needs (Ash Course) BUS 372 Week 2 DQ 1 Profit Interest and Employee Interest (Ash Course) BUS 372 Week 2 DQ 2 Union Requirements (Ash Course) BUS 372 Week 2 Assignment Changing Landscape of Unions (Ash Course) BUS 372 Week 2 Quiz (Ash Course) BUS 372 Week 3 DQ 1 Strikes (Ash Course) BUS ...

  12. BUS 372 Tutorials / bus372dotcom

    OpenAIRE

    sunshine3811

    2015-01-01

    For more course tutorials visit www.bus372.com       BUS 372 Week 1 DQ 1 The Role of Unionization (Ash Course) BUS 372 Week 1 DQ 2 Meeting Member Needs (Ash Course) BUS 372 Week 2 DQ 1 Profit Interest and Employee Interest (Ash Course) BUS 372 Week 2 DQ 2 Union Requirements (Ash Course) BUS 372 Week 2 Assignment Changing Landscape of Unions (Ash Course) BUS 372 Week 2 Quiz (Ash Course) BUS 372 Week 3 DQ 1 Strikes (Ash Course) BUS ...

  13. Fuel Cell Transit Bus Evaluations: Joint Evaluation Plan for the U.S. Department of Energy and the Federal Transit Administration (Report and Appendix)

    Energy Technology Data Exchange (ETDEWEB)

    Eudy, L.; Chandler, K.

    2010-11-01

    This document describes the fuel cell transit bus evaluations performed by the National Renewable Energy Laboratory (NREL) and funded by the U.S. Department of Energy (DOE) and the U.S. Department of Transportation's Federal Transit Administration (FTA). This document provides a description of the demonstration sites, funding sources, and data collection activities for fuel cell transit bus evaluations currently planned from FY10 through FY12.

  14. Texas Hydrogen Highway Fuel Cell Hybrid Bus and Fueling Infrastructure Technology Showcase - Final Scientific/Technical Report

    Energy Technology Data Exchange (ETDEWEB)

    Hitchcock, David

    2012-06-29

    The Texas Hydrogen Highway project has showcased a hydrogen fuel cell transit bus and hydrogen fueling infrastructure that was designed and built through previous support from various public and private sector entities. The aim of this project has been to increase awareness among transit agencies and other public entities on these transportation technologies, and to place such technologies into commercial applications, such as a public transit agency. The initial project concept developed in 2004 was to show that a skid-mounted, fully-integrated, factory-built and tested hydrogen fueling station could be used to simplify the design, and lower the cost of fueling infrastructure for fuel cell vehicles. The approach was to design, engineer, build, and test the integrated fueling station at the factory then install it at a site that offered educational and technical resources and provide an opportunity to showcase both the fueling station and advanced hydrogen vehicles. The two primary technology components include: Hydrogen Fueling Station: The hydrogen fueling infrastructure was designed and built by Gas Technology Institute primarily through a funding grant from the Texas Commission on Environmental Quality. It includes hydrogen production, clean-up, compression, storage, and dispensing. The station consists of a steam methane reformer, gas clean-up system, gas compressor and 48 kilograms of hydrogen storage capacity for dispensing at 5000 psig. The station is skid-mounted for easy installation and can be relocated if needed. It includes a dispenser that is designed to provide temperaturecompensated fills using a control algorithm. The total station daily capacity is approximately 50 kilograms. Fuel Cell Bus: The transit passenger bus built by Ebus, a company located in Downey, CA, was commissioned and acquired by GTI prior to this project. It is a fuel cell plug-in hybrid electric vehicle which is ADA compliant, has air conditioning sufficient for Texas operations

  15. BUS 401 Courses / bus401tutorialdotcom

    OpenAIRE

    uophelp

    2015-01-01

     FOR MORE CLASSES VISIT www.bus401tutorial.com BUS 401 Week 1 DQ 1 Corporate Income Tax and Real Interest Rates (Ash Course) BUS 401 Week 1 DQ 2 Cash Flow and Ratio Analysis (Ash Course)  BUS 401 Week 1 Assignment Ratio Analysis (Ash Course) BUS 401 Week 1 Quiz (Ash Course) BUS 401 Week 2 DQ 1 Annuity and Capital Asset Pricing (Ash Course) BUS 401 Week 2 DQ 2 Bonds and Common Stock (Ash Course) BUS 401 Week 2 Assignment Alternative Investments (Ash Co...

  16. BUS 401 COURSES / bus401tutordotcom

    OpenAIRE

    uophelp

    2015-01-01

    FOR MORE CLASSES VISIT www.bus401tutor.com   BUS 401 Week 1 DQ 1 Corporate Income Tax and Real Interest Rates (Ash Course) BUS 401 Week 1 DQ 2 Cash Flow and Ratio Analysis (Ash Course)  BUS 401 Week 1 Assignment Ratio Analysis (Ash Course) BUS 401 Week 1 Quiz (Ash Course) BUS 401 Week 2 DQ 1 Annuity and Capital Asset Pricing (Ash Course) BUS 401 Week 2 DQ 2 Bonds and Common Stock (Ash Course) BUS 401 Week 2 Assignment Alternative Investments (Ash ...

  17. Fuel Cell/Battery Powered Bus System. Final Report for period August 1987 - December 31, 1997

    Energy Technology Data Exchange (ETDEWEB)

    Wimmer, R.

    1999-01-01

    Today, fuel cell systems are getting much attention from the automotive industry as a future replacement for the internal combustion engine (ICE). Every US automobile manufacturer and most foreign firms have major programs underway to develop fuel cell engines for transportation. The objective of this program was to investigate the feasibility of using fuel cells as an alternative to the ICE. Three such vehicles (30-foot buses) were introduced beginning in 1994. Extensive development and operational testing of fuel cell systems as a vehicle power source has been accomplished under this program. The development activity investigated total systems configuration and effectiveness for vehicle operations. Operational testing included vehicle performance testing, road operations, and extensive dynamometer emissions testing.

  18. 77 FR 25529 - Over-the-Road Bus Accessibility Program Grants

    Science.gov (United States)

    2012-04-30

    ... disability community and the transportation industry. Project ACTION provides training, resources and.... Overview II. Program Purpose III. Program Information A. Award Information B. Eligible Applicants C... Criteria VI. Award Administration Information VII. Agency Contacts I. Overview A. Authority The program...

  19. BUS 660 ASH Course Tutorial / bus660dotcom

    OpenAIRE

    vasanthi moola

    2015-01-01

    BUS 660 Entire Course For more course tutorials visit www.bus660.com   BUS 660 Week 1 Assignment Developing Leaders at UPS BUS 660 Week 2 Assignment Leadership Style BUS 660 Week 3 Assignment Leadership Traits BUS 660 Week 4 Assignment Leadership Skills BUS 660 Week 5 Assignment Big Changes for a Small Hospital BUS 660 Week 6 Assignment Research Paper BUS 660 Week 1 DQ 1 Leadership Defined BUS 660 Week 1 DQ 2 Education and Experience BUS 66...

  20. Analysis of robustness of urban bus network

    Science.gov (United States)

    Tao, Ren; Yi-Fan, Wang; Miao-Miao, Liu; Yan-Jie, Xu

    2016-02-01

    In this paper, the invulnerability and cascade failures are discussed for the urban bus network. Firstly, three static models(bus stop network, bus transfer network, and bus line network) are used to analyse the structure and invulnerability of urban bus network in order to understand the features of bus network comprehensively. Secondly, a new way is proposed to study the invulnerability of urban bus network by modelling two layered networks, i.e., the bus stop-line network and the bus line-transfer network and then the interactions between different models are analysed. Finally, by modelling a new layered network which can reflect the dynamic passenger flows, the cascade failures are discussed. Then a new load redistribution method is proposed to study the robustness of dynamic traffic. In this paper, the bus network of Shenyang City which is one of the biggest cities in China, is taken as a simulation example. In addition, some suggestions are given to improve the urban bus network and provide emergency strategies when traffic congestion occurs according to the numerical simulation results. Project supported by the National Natural Science Foundation of China (Grant Nos. 61473073, 61374178, 61104074, and 61203329), the Fundamental Research Funds for the Central Universities (Grant Nos. N130417006, L1517004), and the Program for Liaoning Excellent Talents in University (Grant No. LJQ2014028).

  1. Global Optimal Energy Management Strategy Research for a Plug-In Series-Parallel Hybrid Electric Bus by Using Dynamic Programming

    OpenAIRE

    Hongwen He; Henglu Tang; Ximing Wang

    2013-01-01

    Energy management strategy influences the power performance and fuel economy of plug-in hybrid electric vehicles greatly. To explore the fuel-saving potential of a plug-in hybrid electric bus (PHEB), this paper searched the global optimal energy management strategy using dynamic programming (DP) algorithm. Firstly, the simplified backward model of the PHEB was built which is necessary for DP algorithm. Then the torque and speed of engine and the torque of motor were selected as the control va...

  2. 77 FR 71865 - Over-the-Road Bus Accessibility Grant Program

    Science.gov (United States)

    2012-12-04

    ... by Section 3038 of the Transportation Equity Act for the 21st Century (TEA-21). The OTRB... FTA's Transportation Electronic Awards Management System (TEAM) for the projects identified in Tables... program was repealed under the Moving Ahead for Progress in the 21st Century Act, signed by...

  3. 76 FR 41323 - Over-the-Road Bus Accessibility Program Grants

    Science.gov (United States)

    2011-07-13

    ... distant points. 4. The applicant maintains a Website showing routes and schedules of its regularly... an additional notification, FTA's system will notify the applicant if there are any problems with the... problems that may have caused a rejection notification. D. Intergovernmental Review This program is...

  4. Programmed cell death

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-31

    The purpose of this conference to provide a multidisciplinary forum for exchange of state-of-the-art information on the role programmed cell death plays in normal development and homeostasis of many organisms. This volume contains abstracts of papers in the following areas: invertebrate development; immunology/neurology; bcl-2 family; biochemistry; programmed cell death in viruses; oncogenesis; vertebrate development; and diseases.

  5. Aids to School Bus Design

    Science.gov (United States)

    1991-01-01

    Navistar International Transportation Corporation, Chicago, IL, used three separate NASA-developed technologies in the design and testing of their 3000 Series Bus Chassis which was developed expressly for school bus applications. For structural analysis, they used the MSC/NASTRAN program which mathematically analyzes a design and predicts how it will hold up under stress. They also used the SPATE 9000 system for non-contact measurement of stress, load transfer mechanisms, detection of hidden flaws, and monitoring structural changes during fatigue testing. SPATE 9000 was based on infrared stress measurement technology developed by Langley Research Center. They also employed the Wyle Ride Quality Meter, which was developed by Langley to aid in passenger aircraft design by providing an accurate measurement of ride vibration and sound level. These numbers translate into a subjective discomfort level index. These technologies contribute to the company's 45-48 percent share of the school bus chassis market.

  6. BUS 210 Course tutorial/ indigohelp

    OpenAIRE

    WVFD

    2015-01-01

    For more classes visit www.indigohelp.com   BUS 210 Week 1 DQ1 and DQ2 BUS 210 Week 1 Checkpoint Business Models and Systems (2 Sets) BUS 210 Week 1 Knowledge Check BUS 210 Week 2 CheckPoint Business Organization  (2 Sets) BUS 210 Week 2 Knowledge Check BUS 210 Week 2 Assignment Evolution of Business Presentation (2 Sets) BUS 210 Week 3 DQ 1 and DQ 2 BUS 210 Week 3 CheckPoint Code of Ethics (2 Sets) BUS 210 Week 3 Knowledge Check BUS 2...

  7. Global Optimal Energy Management Strategy Research for a Plug-In Series-Parallel Hybrid Electric Bus by Using Dynamic Programming

    Directory of Open Access Journals (Sweden)

    Hongwen He

    2013-01-01

    Full Text Available Energy management strategy influences the power performance and fuel economy of plug-in hybrid electric vehicles greatly. To explore the fuel-saving potential of a plug-in hybrid electric bus (PHEB, this paper searched the global optimal energy management strategy using dynamic programming (DP algorithm. Firstly, the simplified backward model of the PHEB was built which is necessary for DP algorithm. Then the torque and speed of engine and the torque of motor were selected as the control variables, and the battery state of charge (SOC was selected as the state variables. The DP solution procedure was listed, and the way was presented to find all possible control variables at every state of each stage in detail. Finally, the appropriate SOC increment is determined after quantizing the state variables, and then the optimal control of long driving distance of a specific driving cycle is replaced with the optimal control of one driving cycle, which reduces the computational time significantly and keeps the precision at the same time. The simulation results show that the fuel economy of the PEHB with the optimal energy management strategy is improved by 53.7% compared with that of the conventional bus, which can be a benchmark for the assessment of other control strategies.

  8. Zero Emission Bay Area (ZEBA) Fuel Cell Bus Demonstration Results. Fourth Report

    Energy Technology Data Exchange (ETDEWEB)

    Eudy, Leslie [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Post, Matthew [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2015-07-02

    This report presents results of a demonstration of fuel cell electric buses (FCEB) operating in Oakland, California. Alameda-Contra Costa Transit District (AC Transit) leads the Zero Emission Bay Area (ZEBA) demonstration, which includes 12 advanced-design fuel cell buses and two hydrogen fueling stations. The FCEBs in service at AC Transit are 40-foot, low-floor buses built by Van Hool with a hybrid electric propulsion system that includes a US Hybrid fuel cell power system and EnerDel lithium-based energy storage system. The buses began revenue service in May 2010.

  9. Impact of Spanish electricity mix, over the period 2008–2030, on the Life Cycle energy consumption and GHG emissions of Electric, Hybrid Diesel-Electric, Fuel Cell Hybrid and Diesel Bus of the Madrid Transportation System

    International Nuclear Information System (INIS)

    Highlights: • We assess the performance of 4 buses that run on different alternative fuel types and technologies. • The buses assessed are Fuel Cell-Hybrid Bus, Hybrid Diesel-Electric Bus, Battery Electric Bus, and a Diesel Bus. • We examine the environmental impact caused by the Life Cycle of each vehicle technology, fossil fuel and energy carrier. • Life Cycle of Battery Electric Bus shows that it has a big potential of improvement in terms of environmental impact. - Abstract: In spite of the advanced research in automotive technology, and the improvement of fuels, the road transport sector continues to be an environmental concern, since the increase in transport demand is offsetting the effects of these technological improvements. Therefore, this poses the following question: what combination of technology and fuel is more efficient in terms of energy consumption and green house gas (GHG) emissions? To fully address this question it is necessary to carry out a Life Cycle Assessment (LCA). This paper presents a global LCA of 4 buses that run on the following fuel types and technologies: (1) Fuel Cell- Hybrid Bus, (2) Hybrid Diesel-Electric Bus (series configuration), (3) Battery Electric Bus and (4) Combustion Ignition Engine Bus. The impact categories assessed are: primary energy consumption, fossil energy and GHG emissions. Among the principal results, we can conclude that the Global LCA of buses (3) and (1) (which are the more sensitive pathways to the electricity mix variation) have for the 2008–2030 period a room for improvement of 25.62% and 28.16% in terms of efficiency of fossil energy consumption and a potential GHG emission reduction of 28.70% and 30.88% respectively

  10. Zero Emission Bay Area (ZEBA) Fuel Cell Bus Demonstration Results: Fifth Report

    Energy Technology Data Exchange (ETDEWEB)

    Eudy, Leslie [National Renewable Energy Lab. (NREL), Golden, CO (United States); Post, Matthew [National Renewable Energy Lab. (NREL), Golden, CO (United States); Jeffers, Matthew [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2016-06-01

    This report presents results of a demonstration of fuel cell electric buses (FCEB) operating in Oakland, California. Alameda-Contra Costa Transit District (AC Transit) leads the Zero Emission Bay Area (ZEBA) demonstration, which includes 13 advanced-design fuel cell buses and two hydrogen fueling stations. The ZEBA partners are collaborating with the U.S. Department of Energy (DOE) and DOE's National Renewable Energy Laboratory (NREL) to evaluate the buses in revenue service. NREL has published four previous reports describing operation of these buses. This report presents new and updated results covering data from January 2015 through December 2015.

  11. Comparative study of two different powertrains for a fuel cell hybrid bus

    Science.gov (United States)

    Gao, Dawei; Jin, Zhenhua; Zhang, Junzhi; Li, Jianqiu; Ouyang, Minggao

    2016-07-01

    The powertrain plays an essential role in improving the tractive performance and the fuel consumption of fuel cell hybrid vehicles. This paper presents a comparative study of two different powertrains for fuel cell hybrid buses. The significant difference between the two powertrains lies in the types and arrangements of the electrical motor. One powertrain employs an induction motor to drive the vehicle, while the other powertrain adopts two permanent magnetic synchronous motors for near-wheel propulsion. Besides, the tiny difference between the proposed powertrain is the supply path of the fuel cell accessories, which can have an effect on the powertrain efficiency. The component parameters and energy management strategies for the two powertrain are determined. The fuel cell hybrid buses equipped with the two powertrains are developed, and some road tests are achieved, according to the chosen procedures or driving cycles. The paper focuses on the tractive performance and energy analysis of the powertrains based on the testing results. Finally, the paper summarizes the relative merits of the proposed powertrains.

  12. Pybus -- A Python Software Bus

    Energy Technology Data Exchange (ETDEWEB)

    Lavrijsen, Wim T.L.P.

    2004-10-14

    A software bus, just like its hardware equivalent, allows for the discovery, installation, configuration, loading, unloading, and run-time replacement of software components, as well as channeling of inter-component communication. Python, a popular open-source programming language, encourages a modular design on software written in it, but it offers little or no component functionality. However, the language and its interpreter provide sufficient hooks to implement a thin, integral layer of component support. This functionality can be presented to the developer in the form of a module, making it very easy to use. This paper describes a Pythonmodule, PyBus, with which the concept of a ''software bus'' can be realized in Python. It demonstrates, within the context of the ATLAS software framework Athena, how PyBus can be used for the installation and (run-time) configuration of software, not necessarily Python modules, from a Python application in a way that is transparent to the end-user.

  13. Pybus - A Python Software Bus

    International Nuclear Information System (INIS)

    A software bus, just like its hardware equivalent, allows for the discovery, installation, configuration, loading, unloading, and run-time replacement of software components, as well as channeling of inter-component communication. Python, a popular open-source programming language, encourages a modular design on software written in it, but it offers little or no component functionality. However, the language and its interpreter provide sufficient hooks to implement a thin, integral layer of component support. This functionality can be presented to the developer in the form of a module, making it very easy to use. This paper describes a Pythonmodule, PyBus, with which the concept of a ''software bus'' can be realized in Python. It demonstrates, within the context of the ATLAS software framework Athena, how PyBus can be used for the installation and (run-time) configuration of software, not necessarily Python modules, from a Python application in a way that is transparent to the end-user

  14. PCI bus demystified

    CERN Document Server

    Abbott, Doug

    2004-01-01

    The peripheral component interconnect (PCI) bus is the dominant bus system used to connect the different elements making up today''s high-performance computer systems. Different PCI implementations have also been developed for such applications as telecommunications and embedded computing. If an application calls for high speed, high reliability, flexible configuration, and bus mastering, then PCI is the only logical bus choice. This book is an applications-oriented introduction to the PCI bus, with an emphasis on implementing PCI in a variety of computer architectures. Special attention is given to industrial and mission-critical applications of PCI bus.·Fully describes PCI electrical specifications, mechanical requirements, and signal types·Covers advanced topics through numerous design examples to increase the readers understanding of the subject ·Includes updated coverage of PCI-X 2.0

  15. Zero Emission Bay Area (ZEBA) Fuel Cell Bus Demonstration: First Results Report

    Energy Technology Data Exchange (ETDEWEB)

    Chandler, K.; Eudy, L.

    2011-08-01

    This report documents the early implementation experience for the Zero Emission Bay Area (ZEBA) Demonstration, the largest fleet of fuel cell buses in the United States. The ZEBA Demonstration group includes five participating transit agencies: AC Transit (lead transit agency), Santa Clara Valley Transportation Authority (VTA), Golden Gate Transit (GGT), San Mateo County Transit District (SamTrans), and San Francisco Municipal Railway (Muni). The ZEBA partners are collaborating with the U.S. Department of Energy (DOE) and DOE's National Renewable Energy Laboratory (NREL) to evaluate the buses in revenue service.

  16. Zero Emission Bay Area (ZEBA) Fuel Cell Bus Demonstration: Second Results Report

    Energy Technology Data Exchange (ETDEWEB)

    Eudy, L.; Chandler, K.

    2012-07-01

    This report presents results of a demonstration of 12 new fuel cell electric buses (FCEB) operating in Oakland, California. The 12 FCEBs operate as a part of the Zero Emission Bay Area (ZEBA) Demonstration, which also includes two new hydrogen fueling stations. This effort is the largest FCEB demonstration in the United States and involves five participating transit agencies. The ZEBA partners are collaborating with the U.S. Department of Energy (DOE) and DOE's National Renewable Energy Laboratory (NREL) to evaluate the buses in revenue service. The first results report was published in August 2011, describing operation of these new FCEBs from September 2010 through May 2011. New results in this report provide an update through April 2012.

  17. Zero Emission Bay Area (ZEBA) Fuel Cell Bus Demonstration Results: Third Report

    Energy Technology Data Exchange (ETDEWEB)

    Eudy, L.; Post, M.

    2014-05-01

    This report presents results of a demonstration of 12 fuel cell electric buses (FCEB) operating in Oakland, California. The 12 FCEBs operate as a part of the Zero Emission Bay Area (ZEBA) Demonstration, which also includes two new hydrogen fueling stations. This effort is the largest FCEB demonstration in the United States and involves five participating transit agencies. The ZEBA partners are collaborating with the U.S. Department of Energy (DOE) and DOE's National Renewable Energy Laboratory (NREL) to evaluate the buses in revenue service. NREL has published two previous reports, in August 2011 and July 2012, describing operation of these buses. New results in this report provide an update covering eight months through October 2013.

  18. Intelligent Bus Stops in the Flexible Bus Systems

    Directory of Open Access Journals (Sweden)

    Razi Iqbal

    2014-09-01

    Full Text Available The purpose of this paper is to discuss Intelligent Bus Stops in a special Demand Responsive Transit (DRT, the Flexible Bus System. These Intelligent Bus Stops are more efficient and information rich than Traditional Bus Stops. The real time synchronization of the Flexible Bus System makes it unique as compared to Traditional Bus Systems. The Main concern is to make Bus Stops intelligent and information rich. Buses are informed about the no. of passengers waiting at the upcoming Bus Stops. If there are no passengers to ride or get off on upcoming Bus Stop, the Bus can skip that Bus Stop and head towards the next Bus Stop where passenger is waiting, which will decrease the ride time of the passengers on the Bus and also the wait time of the passengers waiting on the upcoming Bus Stops. Providing more information at Bus Stops about the Destination (Time to Destination, Distance to Destination etc. and Buses (Bus Location, Arrival Time of Bus etc. makes it easier for the passengers to decide whether to ride a particular Bus or not.

  19. 基于双层规划的城市公交专用道优化设计%Optimum design of city bus lane based on bi-level programming

    Institute of Scientific and Technical Information of China (English)

    陈芳; 龙建成

    2016-01-01

    In order to improve the bus service level ,more and more cities have opened the bus lanes . But the bus lanes will aggravate the car right ,thus the relationship between the car and the bus should be balanced scientifically from the perspective of overall system .In order to guarantee the min-imum travel cost of the traveler ,and considering the travel selection behavior of the traveler ,a bi-lev-el programming model for bus lane network optimization is built from the perspective of the whole city traffic network .According to the flow characteristic of the car and the bus on the road with bus lanes , the impedance function based on bus lane network is proposed and the dual-mode traffic assignment model is established .The lower-layer flow assignment and the bi-level programming model are solved by using the Frank-Wolfe algorithm and the genetic algorithm respectively .Finally ,the example anal-ysis with real traffic network is carried out to verify the validity of the proposed model and algorithm .%为了提高公交车的服务水平,很多城市开辟了公交专用道,由于公交专用道的设置会降低小汽车的路权,必须从系统整体的角度来设置公交专用道以科学权衡小汽车与公交车的路权分配。文章从城市交通网络的整体出发,以出行者总体出行成本最小为目标,充分考虑出行者的出行选择行为,提出了城市公交专用道优化设计的双层规划模型;结合设置公交专用道的路段上公交车与小汽车的流量特性,提出了基于公交专用道网络的道路阻抗函数,构造双模式交通分配模型;分别使用Frank-Wolfe算法和遗传算法进行下层流量分配和双层规划模型的求解,并运用交通网络进行实例分析,验证了所提模型和算法的有效性。

  20. Global analysis of ligand sensitivity of estrogen inducible and suppressible genes in MCF7/BUS breast cancer cells by DNA microarray

    OpenAIRE

    Coser, Kathryn R.; Chesnes, Jessica; Hur, Jingyung; Ray, Sandip; Isselbacher, Kurt J.; Shioda, Toshi

    2003-01-01

    To obtain comprehensive information on 17β-estradiol (E2) sensitivity of genes that are inducible or suppressible by this hormone, we designed a method that determines ligand sensitivities of large numbers of genes by using DNA microarray and a set of simple Perl computer scripts implementing the standard metric statistics. We used it to characterize effects of low (0–100 pM) concentrations of E2 on the transcriptome profile of MCF7/BUS human breast cancer cells, whose E2 dose-dependent growt...

  1. TPG bus passes

    CERN Multimedia

    Staff Association

    2013-01-01

    The CERN Staff Association will stop selling TPG bus passes. All active and retired members of the CERN personnel will be able to purchase Unireso bus passes from the CERN Hostel - Building 39 (Meyrin site) from 1st February 2013. For more information: https://cds.cern.ch/journal/CERNBulletin/2013/04/Announcements/1505279?ln=en

  2. Voluntary Truck and Bus Fuel-Economy-Program marketing plan. Final technical report, September 29, 1980-January 29, 1982

    Energy Technology Data Exchange (ETDEWEB)

    None

    1982-01-01

    The aim of the program is to improve the utilization of fuel by commercial trucks and buses by updating and implementing specific approaches for educating and monitoring the trucking industry on methods and means of conserving fuels. The following outlines the marketing plan projects: increase use of program logo by voluntary program members and others; solicit trade publication membership and support; brief Congressional delegations on fuel conservation efforts; increase voluntary program presence before trade groups; increase voluntary program presence at truck and trade shows; create a voluntary program display for use at trade shows and in other areas; review voluntary program graphics; increase voluntary program membership; and produce placemats carrying fuel conservation messages; produce a special edition of Fuel Economy News, emphasizing the driver's involvement in fuel conservation; produce posters carrying voluntary program fuel conservation message. Project objectives, activities, and results for each project are summarized.

  3. The erigone bus study

    International Nuclear Information System (INIS)

    A study has been made of some factors determining the performance and cost-effectiveness of microcomputer bus systems implemented in Europa crates. An experimental system has been specified and a number of modules constructed in accordance with the specification, in order to test the validity of some of the ideas proposed. It has been demonstrated that the bus interfacing logic can be simple and inexpensive, while maintaining a high degree of processor independence and also a high degree of transparency in operation. The number of pins required by the bus is minimized by multiplexing address and data. A series termination for the drive of the multiplexed lines permits cross-talk to be reduced to insignificant levels: this technique is recommended for wider application. The experimental bus is proposed as a basis for the construction of simple microcomputer-based instrumentation systems. (orig.)

  4. Bus.py

    Energy Technology Data Exchange (ETDEWEB)

    2014-07-21

    GridLAB-D is an agent? based distribution system simulation environment that allows fine-grained end-user models, including geospatial and network topology detail. GridLAB-D addresses the lack of runtime interaction by designing a flexible communication interface, Bus.py (pronounced bus-dot-pie), that uses Python to pass messages between one or more GridLAB-D instances and a Smart Grid simulator.

  5. LHC on the bus

    CERN Document Server

    Laëtitia Pedroso

    2010-01-01

    On 15 December, an airport bus will be transformed in the image of CERN. The bus will be seen by the thousands of travellers arriving in Geneva, informing them of the possibility to visit CERN.   Sketch of the bus. The good relationship between Geneva International Airport and CERN started several years ago. In 2004 the airport put advertising space in the arrivals area at CERN's disposal free of charge. Now, starting on 15 December, a 40-foot long bus will display a giant sticker advertisement depicting CERN as it takes passengers over the airport tarmac to their planes. This is no ordinary sticker, and it was no mean task to attach it to the bus. The task of producing and attaching it was entrusted to Geneva-based specialists Mathys SA. With the ski season opening on 15 December, there will be many travellers arriving at the airport, and the bus will be ready to receive them. When one thinks of CERN, the subjects that naturally come to mind are the LHC, the mysteries of the Universe...

  6. BUS 660 Ash course tutorial / uophelp

    OpenAIRE

    uophelp

    2015-01-01

      www.uophelp.com         BUS 660 Week 1 Assignment Developing Leaders at UPS BUS 660 Week 2 Assignment Leadership Style BUS 660 Week 3 Assignment Leadership Traits BUS 660 Week 4 Assignment Leadership Skills BUS 660 Week 5 Assignment Big Changes for a Small Hospital BUS 660 Week 6 Assignment Research Paper BUS 660 Week 1 DQ 1 Leadership Defined BUS 660 Week 1 DQ 2 Education and Experience BUS 660 Week 2 DQ 1 Lea...

  7. Global analysis of ligand sensitivity of estrogen inducible and suppressible genes in MCF7/BUS breast cancer cells by DNA microarray.

    Science.gov (United States)

    Coser, Kathryn R; Chesnes, Jessica; Hur, Jingyung; Ray, Sandip; Isselbacher, Kurt J; Shioda, Toshi

    2003-11-25

    To obtain comprehensive information on 17beta-estradiol (E2) sensitivity of genes that are inducible or suppressible by this hormone, we designed a method that determines ligand sensitivities of large numbers of genes by using DNA microarray and a set of simple Perl computer scripts implementing the standard metric statistics. We used it to characterize effects of low (0-100 pM) concentrations of E2 on the transcriptome profile of MCF7/BUS human breast cancer cells, whose E2 dose-dependent growth curve saturated with 100 pM E2. Evaluation of changes in mRNA expression for all genes covered by the DNA microarray indicated that, at a very low concentration (10 pM), E2 suppressed approximately 3-5 times larger numbers of genes than it induced, whereas at higher concentrations (30-100 pM) it induced approximately 1.5-2 times more genes than it suppressed. Using clearly defined statistical criteria, E2-inducible genes were categorized into several classes based on their E2 sensitivities. This approach of hormone sensitivity analysis revealed that expression of two previously reported E2-inducible autocrine growth factors, transforming growth factor alpha and stromal cell-derived factor 1, was not affected by 100 pM and lower concentrations of E2 but strongly enhanced by 10 nM E2, which was far higher than the concentration that saturated the E2 dose-dependent growth curve of MCF7/BUS cells. These observations suggested that biological actions of E2 are derived from expression of multiple genes whose E2 sensitivities differ significantly and, hence, depend on the E2 concentration, especially when it is lower than the saturating level, emphasizing the importance of characterizing the ligand dose-dependent aspects of E2 actions. PMID:14610279

  8. Improved design of HIRFL-CSR EVME bus controller

    International Nuclear Information System (INIS)

    The EVME bus controller which is a key component of the HIRFL-CSR control system was improved. Besides reconfiguring the embedded Linux, a utility program was developed for data exchange between the controller and the database. The bus controller is based on ARM920T(ARM9) micro processor which is BGA packaged. The bus controller has the universal interface of VGA display, keyboard, and mouse. The backboard interface logic is programmed in an in-system configurable FPGA device. The bus can drive high current up to 64 mA, with the flexibility of the programmable signal definitions. All the improved performance helped the EVME bus controller play a crucial role in HIRFL-CSR control system. (authors)

  9. BusTechn

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Introduced the characteristics of series communicat io n I 2C bus and basic communication protocol, and introduced the application of the bus I 2C according to the image sensor OV7610.The computer correspondence s tyle can be divided the parallel correspondence and the series correspondence. T he rate of series correspondence is rapid, and the property of real time is exce llent. Because the number of ports which it takes is great, it is not proper to miniaturize. Whereas the rate of series corresponden...

  10. Learning NServiceBus

    CERN Document Server

    Boike, David

    2013-01-01

    This is a practical tutorial containing hands-on examples for creating a messaging and SOA based service bus.This book is for .NET developers who are looking for ways to overcome problems related to buggy third party web service integrations, codebases that have grown into a big ball of mud, and batch jobs failure.

  11. BUS 401 Ash course tutorial / uophelp

    OpenAIRE

    uophelp

    2015-01-01

    For more course tutorials visit www.uophelp.com   BUS 401 Week 1 DQ 1 Corporate Income Tax and Real Interest Rates BUS 401 Week 1 DQ 2 Cash Flow and Ratio Analysis BUS 401 Week 1 Assignment Ratio Analysis BUS 401 Week 1 Quiz BUS 401 Week 2 DQ 1 Annuity and Capital Asset Pricing BUS 401 Week 2 DQ 2 Bonds and Common Stock BUS 401 Week 2 Assignment Alternative Investments BUS 401 Week 2 Quiz BUS 401 Week 3 DQ 1 NPV, PI, and IRR BUS 401 Week 3 ...

  12. BUS 437 UOP Course Tutorial/ Tutorialrank

    OpenAIRE

    john

    2015-01-01

    For more course tutorials visit www.tutorialrank.com Tutorial Purchased: 4 Times, Rating: A+   ASHFORD BUS 437 Week 1 Assignment Company Description ASHFORD BUS 437 Week 1 DQ 1 Writing the Business Plan ASHFORD BUS 437 Week 1 DQ 2 Using Outside Help to Write the Plan ASHFORD BUS 437 Week 2 Assignment Marketing Section ASHFORD BUS 437 Week 2 DQ 1 Customer Survey ASHFORD BUS 437 Week 2 DQ 2 Industry Analysis ASHFORD BUS 437 Week 3 Assignment Strategy...

  13. Co-simulation Analysis of Increased Program Pure Electric Bus Based on Cruise and Matlab Software%基于Cruise和Matlab的增程式电动车联合仿真分析

    Institute of Scientific and Technical Information of China (English)

    尹剑

    2012-01-01

    According to the Cruise and Matlab Co-simulation for the pure electric buses,the author presents the simulation model and analysis of the increased program pure electric bus based on the precise management to the battery SOC.%在对纯电动客车进行Cruise和Matlab联合仿真的基础上,提出基于电池SOC精确管理的增程式电动客车的仿真模型及分析。

  14. Global Optimization for Bus Line Timetable Setting Problem

    Directory of Open Access Journals (Sweden)

    Qun Chen

    2014-01-01

    Full Text Available This paper defines bus timetables setting problem during each time period divided in terms of passenger flow intensity; it is supposed that passengers evenly arrive and bus runs are set evenly; the problem is to determine bus runs assignment in each time period to minimize the total waiting time of passengers on platforms if the number of the total runs is known. For such a multistage decision problem, this paper designed a dynamic programming algorithm to solve it. Global optimization procedures using dynamic programming are developed. A numerical example about bus runs assignment optimization of a single line is given to demonstrate the efficiency of the proposed methodology, showing that optimizing buses’ departure time using dynamic programming can save computational time and find the global optimal solution.

  15. BUS 402 Ash course tutorial / uophelp

    OpenAIRE

    uophelp-

    2015-01-01

    For more course tutorials visit www.uophelp.com     BUS 402 Week 1 DQ 1 Environmental Changes BUS 402 Week 1 DQ 2 Vision and Mission BUS 402 Week 2 DQ 1 Components of External Environment  BUS 402 Week 2 DQ 2 Components of Internal Analysis BUS 402 Week 2 Assignment Starbucks S.W.O.T. Analysis BUS 402 Week 3 DQ 1 Market Positioning Strategies BUS 402 Week 3 DQ 2 Vertical Integration BUS 402 Week 4 DQ 1 International Markets BUS 40...

  16. BUS 642 Ash course tutorial / uophelp

    OpenAIRE

    uophelp

    2015-01-01

    www.uophelp.com     BUS 642 Week 1 DQ 1 Scientific Thinking (Ash Course) BUS 642 Week 1 DQ 2 Making Research Decisions (Ash Course) BUS 642 Week 1 Exercises (Ash Course) BUS 642 Week 2 DQ 1 Ethics in Business Research (Ash Course) BUS 642 Week 2 DQ 2 Design of Research (Ash Course) BUS 642 Week 2 Exercises (Ash Course) BUS 642 Week 3 DQ 1 Measurement Scales (Ash Course) BUS 642 Week 3 DQ 2 Clarifying the Research Questions (Ash Course) BUS...

  17. BUS 437 Ash course tutorial / uophelp

    OpenAIRE

    uophelp

    2015-01-01

    For more course tutorials visit www.uophelp.com   BUS 437 Week 1 Assignment Company Description BUS 437 Week 1 DQ 1 Writing the Business Plan BUS 437 Week 1 DQ 2 Using Outside Help to Write the Plan BUS 437 Week 2 Assignment Marketing Section BUS 437 Week 2 DQ 1 Customer Survey BUS 437 Week 2 DQ 2 Industry Analysis BUS 437 Week 3 Assignment Strategy, Implementation, & Management Sections BUS 437 Week 3 DQ 1 Implementation BUS 437 Week 3 DQ ...

  18. High speed bus technology development

    Science.gov (United States)

    Modrow, Marlan B.; Hatfield, Donald W.

    1989-09-01

    The development and demonstration of the High Speed Data Bus system, a 50 Million bits per second (Mbps) local data network intended for avionics applications in advanced military aircraft is described. The Advanced System Avionics (ASA)/PAVE PILLAR program provided the avionics architecture concept and basic requirements. Designs for wire and fiber optic media were produced and hardware demonstrations were performed. An efficient, robust token-passing protocol was developed and partially demonstrated. The requirements specifications, the trade-offs made, and the resulting designs for both a coaxial wire media system and a fiber optics design are examined. Also, the development of a message-oriented media access protocol is described, from requirements definition through analysis, simulation and experimentation. Finally, the testing and demonstrations conducted on the breadboard and brassboard hardware is presented.

  19. Implementation of an AMBA Advanced High Performance Bus protocol IP block

    OpenAIRE

    Mahendra Vucha Sandeep Magarde; Miss. Shruti Bhargava; Rishabh Singh Kurmi

    2011-01-01

    The design of an AMBA advanced high performance bus (AHB) protocol IP block is presented in this paper. The AHB (Advanced High-performance Bus) is a high-performance bus in AMBA (Advanced Microcontroller Bus Architecture) family. This AHB can be used in high clock frequency system modules. The AHB acts as the high-performance system backbone bus. AHB supports the efficient connection of processors, on-chip memories and off-chip external memory interfaces with low-power peripheral macro cell f...

  20. 燃料电池公共汽车在北京和上海载客示范评价%Evaluation on Fuel Cell Bus Demonstration in Beijing and Shanghai

    Institute of Scientific and Technical Information of China (English)

    王菊; 尤可为; 于丹

    2013-01-01

    The fuel cell bus demonstration in Beijing and Shanghai is evaluated and analyzed in this paper, the life cycle assessment (LCA) for fuel cell bus demonstration in Beijing is conducted by the energy analysis method of GREET. The total energy consumption, fossil energy consumption, petroleum energy consumption, greenhouse gas emission and economy are calculated for the fuel cell bus using different hydrogen production way such as water electrolysis and natural gas reforming. The findings can provide reference for future demonstration project.%针对在北京、上海开展的燃料电池公共汽车载客示范运行情况进行了评价分析,并采用全生命周期GREET能量分析方法对北京燃料电池公共汽车示范项目进行了全生命周期综合评价。对于燃料电池汽车采用电解水制氢及天然气重整制氢等不同制氢方式的总能量消耗、化石能量消耗、石油能量消耗、温室气体排放和经济性等进行了综合分析,分析结果可为开展类似的示范项目提供参考。

  1. An Optimization Model for the Selection of Bus-Only Lanes in a City.

    Directory of Open Access Journals (Sweden)

    Qun Chen

    Full Text Available The planning of urban bus-only lane networks is an important measure to improve bus service and bus priority. To determine the effective arrangement of bus-only lanes, a bi-level programming model for urban bus lane layout is developed in this study that considers accessibility and budget constraints. The goal of the upper-level model is to minimize the total travel time, and the lower-level model is a capacity-constrained traffic assignment model that describes the passenger flow assignment on bus lines, in which the priority sequence of the transfer times is reflected in the passengers' route-choice behaviors. Using the proposed bi-level programming model, optimal bus lines are selected from a set of candidate bus lines; thus, the corresponding bus lane network on which the selected bus lines run is determined. The solution method using a genetic algorithm in the bi-level programming model is developed, and two numerical examples are investigated to demonstrate the efficacy of the proposed model.

  2. An Interleaved Reduced-Component-Count Multivoltage Bus DC/DC Converter for Fuel Cell Powered Electric Vehicle Applications

    Energy Technology Data Exchange (ETDEWEB)

    Tang, Lixin [ORNL; Su, Gui-Jia [ORNL

    2008-01-01

    An interleaved reduced-component-count dc/dc converter is proposed for power management in fuel cell powered vehicles with a multivoltage electric net. The converter is based on a simplified topology and can handle more power with less ripple current, therefore reducing the capacitor requirements, making it more suited for fuel cell powered vehicles in the near future. A prototype rated at 4.3 kW was built and tested to verify the proposed topology.

  3. BUS 611 Ash course tutorial / uophelp

    OpenAIRE

    uophelp

    2015-01-01

    For more course tutorials visit www.uophelp.com   BUS 611 Week 1 Assignment Article Review (Ash Course) BUS 611 Week 2 Assignment Project Risk (Ash Course) BUS 611 Week 3 Assignment WBS (Ash Course) BUS 611 Week 4 Assignment Integrated Project Management Tools (Ash Course) BUS 611 Week 5 Assignment Monthly Status Reports (Ash Course) BUS 611 Week 6 Final Research Paper (Ash Course)  

  4. Investigation of path dependence in commercial lithium-ion cells for pure electric bus applications: Aging mechanism identification

    Science.gov (United States)

    Ma, Zeyu; Jiang, Jiuchun; Shi, Wei; Zhang, Weige; Mi, Chunting Chris

    2015-01-01

    There is a growing need to provide more realistic and accurate State of Health estimations for batteries in electric vehicles. Thus, it is necessary to research various lithium-ion cell aging processes, including cell degradation and related path dependence. This paper focuses on quantitative analyses of cell aging path dependence in a repeatable laboratory setting, considering the influence of duty cycles, depth of discharge (DOD), and the frequency and severity of the thermal cycle, as reflected in pure electric buses operated in Beijing. Incremental capacity analysis (ICA) and differential voltage analysis (DVA) are applied to infer cell degradation mechanisms and quantify the attributions to capacity fade. It was observed that the cells experienced a higher rate of aging at 80% DOD and an accelerated aging at 40 °C in the thermal cycling, as a result of possible loss of active material (LAM) in both electrodes, in addition to the loss of lithium inventory (LLI) and inhibited kinetics. The slight capacity fade from low-temperature extremes likely caused by LLI due to lithium plating, whereas the noticeable fade after the high-temperature excursion was likely caused by LAM and hindrance to kinetics. These results may lead to improved battery management in EV applications.

  5. BUS 620 Ash course tutorial / uophelp

    OpenAIRE

    uophelp

    2015-01-01

    For more course tutorials visit www.uophelp.com   BUS 620 Week 1 DQ 1 What is Marketing (Ash Course) BUS 620 Week 1 DQ 2 Marketing Strategies (Ash Course) BUS 620 Week 1 The Future of the New York Times (Ash Course) BUS 620 Week 2 DQ 1 Buyer Behavior (Ash Course) BUS 620 Week 2 DQ 2 Customer Needs (Ash Course) BUS 620 Week 2 Industry Forecasting (Ash Course) BUS 620 Week 3 DQ 1 Braining Nordstrom (Ash Course) BUS 620 Week 3 DQ 2 Marketing Segmentat...

  6. Learning NServiceBus Sagas

    CERN Document Server

    Helton, Rich

    2015-01-01

    If you are an Enterprise C# developer who wishes to extend your knowledge of NServiceBus and Enterprise Service Bus in C#, this is the book for you. This book is designed to enhance the education of ESBs and their messaging, whether you are a beginner or a seasoned expert in Enterprise C#, Apex, and Visualforce pages.

  7. Design and Instantiation of Increased Program Bus Power Train System%增程式公交车动力系统设计及实例化研究

    Institute of Scientific and Technical Information of China (English)

    李涛; 陈猛

    2011-01-01

    基于城市公交客车行驶特性的分析,对增程式城市公交客车动力系统进行了方案设计,并对动力总成零部件(增程器、驱动电机、动力电池组)进行了选型计算。结合增程式动力系统特点,开发了利用增程器延长续驶里程的增程式城市公交客车。在公交工况下对整车进行了组装试验,通过各项分析验证了增程式城市公交客车的节能与环保的特点,该动力系统可以满足整车预设的动力性和经济性要求。%Based on the characteristics analysis of city buses,a power train system for increase program city bus was designed,and the main components of power train system(increase mileage device,drive motor and battery) were selected and calculated.With increased program power train system characteristic we developed a city bus of increased program,and it used increase mileage device extended by increasing range.Under public transport working conditions for vehicle assemble and test,and through the analysis of the technical characteristics it is proved that increased program buses are fuel-saving and eco-friendly,can satisfy the characteristics of vehicle performance and fuel economy.

  8. Hydrogen and Fuel Cell Transit Bus Evaluations: Joint Evaluation Plan for the U.S. Department of Energy and the Federal Transit Administration (Report and Appendix)

    Energy Technology Data Exchange (ETDEWEB)

    Eudy, L.; Chandler, K.

    2008-05-01

    This document describes the hydrogen transit bus evaluations performed by the National Renewable Energy Laboratory (NREL) and funded by the U.S. Department of Energy (DOE) and the U.S. Department of Transportation's Federal Transit Administration (FTA).

  9. The Myth of the "Ideal Bus"

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ Does as an ideal bus technology exist? Many companies have and will promote a single technology as the ideal bus that will meet all application needs, but in actuality, each bus technology has its own strengths and weaknesses and thus is appropriate for different applications. History has shown the folly of claiming an ideal bus for every application.

  10. BUS 402 UOP Course Tutorial/ Tutorialrank

    OpenAIRE

    jonh

    2015-01-01

    For more course tutorials visit www.tutorialrank.com Tutorial Purchased: 4 Times, Rating: A+   ASHFORD BUS 402 Week 1 DQ 1 Environmental Changes ASHFORD BUS 402 Week 1 DQ 2 Vision and Mission ASHFORD BUS 402 Week 2 DQ 1 Components of External Environment ASHFORD BUS 402 Week 2 DQ 2 Components of Internal Analysis ASHFORD BUS 402 Week 2 Assignment Starbucks S.W.O.T. Analysis ASHFORD BUS 402 Week 3 DQ 1 Market Positioning Strategies ASHFORD BUS 402 W...

  11. How to Cut Costs by Saving School Bus Fuel.

    Science.gov (United States)

    Seiff, Hank

    A program started in Washington County, Maryland in 1980 has been successful in saving school bus fuel and bringing down transportation costs incurred by its fleet of 200 buses. Driver training and motivation, as well as a partial transfer to diesel buses, are at the heart of the program. The drivers are taught five fuel saving techniques: cut…

  12. BUS 599 Str course tutorial / uophelp

    OpenAIRE

    uophelp

    2015-01-01

    For more course tutorials visit www.uophelp.com   BUS 599 Week 1 Assignment Crafting and Executing Strategy Case JetBlue Airways BUS 599 Assignment #2 Competitive Forces and SWOT Analysis # Case Whole Foods Market BUS 599 Week 3 Assignment Foreign Market Entry and Diversification Case Corona Beer BUS 599 Week 4 Assignment HRM Issues Diversification Strategies Case Nucor Corporation BUS 599 Week 5 Assignment Corporate Culture Leadership Actions for Strategy Imp...

  13. SCHOOL BUS GARAGES, 1966 REVISION.

    Science.gov (United States)

    JOHNSON, HERBERT F.

    STANDARDS AND RECOMMENDATIONS ARE GIVEN FOR THE DESIGN AND CONSTRUCTION OF SCHOOL BUS GARAGES INCLUDING BRIEF DISCUSSIONS OF--(1) SITE DEVELOPMENT, (2) DESIGN AND CONSTRUCTION, AND (3) MECHANICAL (HEATING, PLUMBING, AND VENTILATION) AND ELECTRICAL FACTORS. (JT)

  14. 76 FR 37184 - Discretionary Bus and Bus Facilities Program

    Science.gov (United States)

    2011-06-24

    ... bicycles to public transportation facilities, to provide shelters and parking facilities for bicycles in or around public transportation facilities, or to install equipment for transporting bicycles on public... or retrofitted hybrid electric propulsion systems and any equipment related to such a system....

  15. 75 FR 23843 - Discretionary Bus and Bus Facilities Program

    Science.gov (United States)

    2010-05-04

    ... private non- profit organizations. This Notice includes priorities established by FTA for these... engaged in public transportation, or private non-profit organizations.'' B. Background Maintaining the... agencies, private non-profit organizations, and private providers engaged in public transportation....

  16. Bus Stop - Environment Connection: Do Characteristics of the Built Environment Correlate with Bus Stop Crime?

    OpenAIRE

    Robin S Liggett; Loukaitou-Sideris, Anastasia; Iseki, Hiroyuki

    2003-01-01

    Can we understand why some bus stops are safe and others are crime-ridden? Can we predict which features of the bus stop environment are likely to encourage or discourage crime? Can we design safer bus stops? These questions are addressed by exploring the relationship between environmental variables and bus stop crime. An earlier study used crime data, along with environmental indicators, for a sample of 60 bus stops in downtown Los Angeles. Crime rates were higher for bus stops near alleys, ...

  17. Wishbone bus Architecture - A Survey and Comparison

    CERN Document Server

    Sharma, Mohandeep; 10.5121/vlsic.2012.3210

    2012-01-01

    The performance of an on-chip interconnection architecture used for communication between IP cores depends on the efficiency of its bus architecture. Any bus architecture having advantages of faster bus clock speed, extra data transfer cycle, improved bus width and throughput is highly desirable for a low cost, reduced time-to-market and efficient System-on-Chip (SoC). This paper presents a survey of WISHBONE bus architecture and its comparison with three other on-chip bus architectures viz. Advanced Micro controller Bus Architecture (AMBA) by ARM, CoreConnect by IBM and Avalon by Altera. The WISHBONE Bus Architecture by Silicore Corporation appears to be gaining an upper edge over the other three bus architecture types because of its special performance parameters like the use of flexible arbitration scheme and additional data transfer cycle (Read-Modify-Write cycle). Moreover, its IP Cores are available free for use requiring neither any registration nor any agreement or license.

  18. 1986 fuel cell seminar: Program and abstracts

    Energy Technology Data Exchange (ETDEWEB)

    None

    1986-10-01

    Ninety nine brief papers are arranged under the following session headings: gas industry's 40 kw program, solid oxide fuel cell technology, phosphoric acid fuel cell technology, molten carbonate fuel cell technology, phosphoric acid fuel cell systems, power plants technology, fuel cell power plant designs, unconventional fuels, fuel cell application and economic assessments, and plans for commerical development. The papers are processed separately for the data base. (DLC)

  19. DIMETHYL ETHER (DME)-FUELED SHUTTLE BUS DEMONSTRATION PROJECT

    Energy Technology Data Exchange (ETDEWEB)

    Elana M. Chapman; Shirish Bhide; Jennifer Stefanik; Howard Glunt; Andre L. Boehman; Allen Homan; David Klinikowski

    2003-04-01

    The objectives of this research and demonstration program are to convert a campus shuttle bus to operation on dimethyl ether, a potential ultra-clean alternative diesel fuel. To accomplish this objective, this project includes laboratory evaluation of a fuel conversion strategy, as well as, field demonstration of the DME-fueled shuttle bus. Since DME is a fuel with no lubricity (i.e., it does not possess the lubricating quality of diesel fuel), conventional fuel delivery and fuel injection systems are not compatible with dimethyl ether. Therefore, to operate a diesel engine on DME one must develop a fuel-tolerant injection system, or find a way to provide the necessary lubricity to the DME. In this project, they have chosen the latter strategy in order to achieve the objective with minimal need to modify the engine. Their strategy is to blend DME with diesel fuel, to obtain the necessary lubricity to protect the fuel injection system and to achieve low emissions. The bulk of the efforts over the past year were focused on the conversion of the campus shuttle bus. This process, started in August 2001, took until April 2002 to complete. The process culminated in an event to celebrate the launching of the shuttle bus on DME-diesel operation on April 19, 2002. The design of the system on the shuttle bus was patterned after the system developed in the engine laboratory, but also was subjected to a rigorous failure modes effects analysis (FMEA, referred to by Air Products as a ''HAZOP'' analysis) with help from Dr. James Hansel of Air Products. The result of this FMEA was the addition of layers of redundancy and over-pressure protection to the system on the shuttle bus. The system became operational in February 2002. Preliminary emissions tests and basic operation of the shuttle bus took place at the Pennsylvania Transportation Institute's test track facility near the University Park airport. After modification and optimization of the system on

  20. Programmed Cell Death During Caenorhabditis elegans Development.

    Science.gov (United States)

    Conradt, Barbara; Wu, Yi-Chun; Xue, Ding

    2016-08-01

    Programmed cell death is an integral component of Caenorhabditis elegans development. Genetic and reverse genetic studies in C. elegans have led to the identification of many genes and conserved cell death pathways that are important for the specification of which cells should live or die, the activation of the suicide program, and the dismantling and removal of dying cells. Molecular, cell biological, and biochemical studies have revealed the underlying mechanisms that control these three phases of programmed cell death. In particular, the interplay of transcriptional regulatory cascades and networks involving multiple transcriptional regulators is crucial in activating the expression of the key death-inducing gene egl-1 and, in some cases, the ced-3 gene in cells destined to die. A protein interaction cascade involving EGL-1, CED-9, CED-4, and CED-3 results in the activation of the key cell death protease CED-3, which is tightly controlled by multiple positive and negative regulators. The activation of the CED-3 caspase then initiates the cell disassembly process by cleaving and activating or inactivating crucial CED-3 substrates; leading to activation of multiple cell death execution events, including nuclear DNA fragmentation, mitochondrial elimination, phosphatidylserine externalization, inactivation of survival signals, and clearance of apoptotic cells. Further studies of programmed cell death in C. elegans will continue to advance our understanding of how programmed cell death is regulated, activated, and executed in general. PMID:27516615

  1. BUS 210 UOP Course Tutorial/ Tutorialrank

    OpenAIRE

    john

    2015-01-01

                      For more course tutorials visit www.tutorialrank.com Tutorial Purchased: 6 Times, Rating: A+   BUS 210 Week 1 DQ1 and DQ2 (UOP Course) BUS 210 Week 1 Checkpoint Business Models and Systems (UOP Course) BUS 210 Week 2 CheckPoint Business Organization (UOP Course) BUS 210 Week 2 Assignment Evolution of Business Presentation (UOP Course) BUS 210 Week 3 DQ 1 and DQ 2 (UOP Course) BUS 210 W...

  2. Black silicon with black bus-bar strings

    DEFF Research Database (Denmark)

    Davidsen, Rasmus Schmidt; Tang, Peter Torben; Mizushima, Io;

    2016-01-01

    We present the combination of black silicon texturing and blackened bus-bar strings as a potential method for obtaining all-black solar panels, while using conventional, front-contacted solar cells. Black silicon was realized by mask-less reactive ion etching resulting in total, average reflectance...... below 0.5% across a 156x156 mm2 silicon wafer. Black bus-bars were realized by oxidized copper resulting in reflectance below 3% in the entire visible wavelength range. The combination of these two technologies may result in aesthetic, all-black panels based on conventional, front-contacted solar cells...

  3. Programmed cell death and cell extrusion in rat duodenum

    DEFF Research Database (Denmark)

    Schauser, Kirsten; Larsson, Lars-Inge

    2005-01-01

    The small intestinal epithelium is continously renewed through a balance between cell division and cell loss. How this balance is achieved is uncertain. Thus, it is unknown to what extent programmed cell death (PCD) contributes to intestinal epithelial cell loss. We have used a battery of techniq...

  4. School bus and children's traffic safety

    Institute of Scientific and Technical Information of China (English)

    PAN Shu-ming; Stephen Hargarten; ZHU Shan-kuan

    2007-01-01

    There is no safer way to transport a child than a school bus. Fatal crashes involving occupants are extremely rare events in the US. In recent years, school bus transportation began to develop in China. We want to bring advanced experience on school bus safety in Western countries such as the US to developing countries.Methods: We searched the papers related to school bus safety from Medline, Chinese Scientific Journals Database and the Web of the National Highway Traffic Safety Administration (NHTSA).Results: There were only 9 papers related to school bus safety, which showed that higher levels of safety standards on school buses, school bus-related transportation and environmental laws and injury prevention were the primary reasons for the desired outcome. Few school bus is related to deaths and injuries in the developed countries.Conclusions: The developing countries should make strict environmental laws and standards on school bus safety to prevent children's injury and death.

  5. CLIMATE CHANGE FUEL CELL PROGRAM

    Energy Technology Data Exchange (ETDEWEB)

    Steven A. Gabrielle

    2004-12-03

    This report discusses the first year of operation of a fuel cell power plant located at the Sheraton Edison Hotel, Edison, New Jersey. PPL EnergyPlus, LLC installed the plant under a contract with the Starwood Hotels & Resorts Worldwide, Inc. A DFC{reg_sign}300 fuel cell, manufactured by FuelCell Energy, Inc. of Danbury, CT was selected for the project. The fuel cell successfully operated from June 2003 to May 2004. This report discusses the performance of the plant during this period.

  6. Multiple Curricula for B Cell Developmental Programming.

    Science.gov (United States)

    Rothenberg, Ellen V

    2016-09-20

    B-1 B cells differ from conventional B-2 B cells functionally, but how these differences relate to the ontogeny of these lineages has been unclear. Two recent Immunity articles, Kristiansen et al. (2016) and Montecino-Rodriguez et al. (2016), now provide insight into the origins of B-1 and B-2 B cells, revealing a multi-layered developmental program and successive waves of B cell precursors.

  7. Multiple Curricula for B Cell Developmental Programming.

    Science.gov (United States)

    Rothenberg, Ellen V

    2016-09-20

    B-1 B cells differ from conventional B-2 B cells functionally, but how these differences relate to the ontogeny of these lineages has been unclear. Two recent Immunity articles, Kristiansen et al. (2016) and Montecino-Rodriguez et al. (2016), now provide insight into the origins of B-1 and B-2 B cells, revealing a multi-layered developmental program and successive waves of B cell precursors. PMID:27653594

  8. HERMES travels by CAN bus

    Science.gov (United States)

    Waller, Lewis G.; Shortridge, Keith; Farrell, Tony J.; Vuong, Minh; Muller, Rolf; Sheinis, Andrew I.

    2014-07-01

    The new HERMES spectrograph represents the first foray by AAO into the use of commercial off-the-shelf industrial field bus technology for instrument control, and we regard the final system, with its relatively simple wiring requirements, as a great success. However, both software and hardware teams had to work together to solve a number of problems integrating the chosen CANopen/CAN bus system into our normal observing systems. A Linux system running in an industrial PC chassis ran the HERMES control software, using a PCI CAN bus interface connected to a number of distributed CANopen/CAN bus I/O devices and servo amplifiers. In the main, the servo amplifiers performed impressively, although some experimentation with homing algorithms was required, and we hit a significant hurdle when we discovered that we needed to disable some of the encoders used during observations; we learned a lot about how servo amplifiers respond when their encoders are turned off, and about how encoders react to losing power. The software was based around a commercial CANopen library from Copley Controls. Early worries about how this heavily multithreaded library would work with our standard data acquisition system led to the development of a very low-level CANopen software simulator to verify the design. This also enabled the software group to develop and test almost all the control software well in advance of the construction of the hardware. In the end, the instrument went from initial installation at the telescope to successful commissioning remarkably smoothly.

  9. Low-inductance bus lines

    Science.gov (United States)

    Kernick, A.

    1977-01-01

    Laminated bus strips and bifilar litz cable connectors for high-power rectifiers, thrisistors, and transistors provide low inductance and eliminate electromagnetic interference in high-power circuits. These techniques offer significant cost advantages because of ease of assembly and consistent high quality of product. Effectiveness makes general usage in static power conversion likely.

  10. Directly connected series coupled HTPEM fuel cell stacks to a Li-ion battery DC bus for a fuel cell electrical vehicle

    DEFF Research Database (Denmark)

    Andreasen, Søren Juhl; Ashworth, Leanne; Remón, Ian Natanael;

    2008-01-01

    The work presented in this paper examines the use of pure hydrogen fuelled high temperature polymer electrolyte membrane (HTPEM) fuel cell stacks in an electrical car, charging a Li-ion battery pack. The car is equipped with two branches of two series coupled 1 kW fuel cell stacks which...... are connected directly parallel to the battery pack during operation. This enables efficient charging of the batteries for increased driving range. With no power electronics used, the fuel cell stacks follow the battery pack voltage, and charge the batteries passively. This saves the electrical and economical...... losses related to these components and their added system complexity. The new car battery pack consists of 23 Li-ion battery cells and the charging and discharging are monitored by a battery management system (BMS) which ensures safe operating conditions for the batteries. The direct connection...

  11. Climate Change Fuel Cell Program

    Energy Technology Data Exchange (ETDEWEB)

    Paul Belard

    2006-09-21

    Verizon is presently operating the largest Distributed Generation Fuel Cell project in the USA. Situated in Long Island, NY, the power plant is composed of seven (7) fuel cells operating in parallel with the Utility grid from the Long Island Power Authority (LIPA). Each fuel cell has an output of 200 kW, for a total of 1.4 mW generated from the on-site plant. The remaining power to meet the facility demand is purchased from LIPA. The fuel cell plant is utilized as a co-generation system. A by-product of the fuel cell electric generation process is high temperature water. The heat content of this water is recovered from the fuel cells and used to drive two absorption chillers in the summer and a steam generator in the winter. Cost savings from the operations of the fuel cells are forecasted to be in excess of $250,000 per year. Annual NOx emissions reductions are equivalent to removing 1020 motor vehicles from roadways. Further, approximately 5.45 million metric tons (5 millions tons) of CO2 per year will not be generated as a result of this clean power generation. The project was partially financed with grants from the New York State Energy R&D Authority (NYSERDA) and from Federal Government Departments of Defense and Energy.

  12. Programmed Cell Death in Neurospora crassa

    Directory of Open Access Journals (Sweden)

    A. Pedro Gonçalves

    2014-01-01

    Full Text Available Programmed cell death has been studied for decades in mammalian cells, but simpler organisms, including prokaryotes, plants, and fungi, also undergo regulated forms of cell death. We highlight the usefulness of the filamentous fungus Neurospora crassa as a model organism for the study of programmed cell death. In N. crassa, cell death can be triggered genetically due to hyphal fusion between individuals with different allelic specificities at het loci, in a process called “heterokaryon incompatibility.” Chemical induction of cell death can also be achieved upon exposure to death-inducing agents like staurosporine, phytosphingosine, or hydrogen peroxide. A summary of the recent advances made by our and other groups on the discovery of the mechanisms and mediators underlying the process of cell death in N. crassa is presented.

  13. Electrical system architecture having high voltage bus

    Science.gov (United States)

    Hoff, Brian Douglas; Akasam, Sivaprasad

    2011-03-22

    An electrical system architecture is disclosed. The architecture has a power source configured to generate a first power, and a first bus configured to receive the first power from the power source. The architecture also has a converter configured to receive the first power from the first bus and convert the first power to a second power, wherein a voltage of the second power is greater than a voltage of the first power, and a second bus configured to receive the second power from the converter. The architecture further has a power storage device configured to receive the second power from the second bus and deliver the second power to the second bus, a propulsion motor configured to receive the second power from the second bus, and an accessory motor configured to receive the second power from the second bus.

  14. Calculation of Flexible Bus-Bars Electrodynamic Stability with Application of Implicit Scheme

    OpenAIRE

    Y. G. Panamarenka

    2008-01-01

    A numerical method for calculation of open-air substations’ flexible bus-bars dynamic at short-circuit has been improved on equations of a flexible elastic string with application of an implicit scheme. On the basis of the numerical method a computer program FLEBUS for calculation of substations’ flexible bus-bars dynamic at short-circuit has been developed. An approbation and an estimation of calculation result reliability have been carried out in accordance with the program while using expe...

  15. General Motors automotive fuel cell program

    Energy Technology Data Exchange (ETDEWEB)

    Fronk, M.H.

    1995-08-01

    The objectives of the second phase of the GM/DOE fuel cell program is to develop and test a 30 kW fuel cell powerplant. This powerplant will be based on a methanol fuel processor and a proton exchange membrane PM fuel cell stack. In addition, the 10 kW system developed during phase I will be used as a {open_quotes}mule{close_quotes} to test automotive components and other ancillaries, needed for transient operation.

  16. Programmed cell death during quinoa perisperm development

    OpenAIRE

    López-Fernández, María Paula; Maldonado, Sara

    2013-01-01

    At seed maturity, quinoa (Chenopodium quinoa Willd.) perisperm consists of uniform, non-living, thin-walled cells full of starch grains. The objective of the present study was to study quinoa perisperm development and describe the programme of cell death that affects the entire tissue. A number of parameters typically measured during programmed cell death (PCD), such as cellular morphological changes in nuclei and cytoplasm, endoreduplication, DNA fragmentation, and the participation of nucle...

  17. Apoptosis: A Review of Programmed Cell Death

    OpenAIRE

    Elmore, Susan

    2007-01-01

    The process of programmed cell death, or apoptosis, is generally characterized by distinct morphological characteristics and energy-dependent biochemical mechanisms. Apoptosis is considered a vital component of various processes including normal cell turnover, proper development and functioning of the immune system, hormone-dependent atrophy, embryonic development and chemical-induced cell death. Inappropriate apoptosis (either too little or too much) is a factor in many human conditions incl...

  18. Programmed cell death and hybrid incompatibility.

    Science.gov (United States)

    Frank, S A; Barr, C M

    2003-01-01

    We propose a new theory to explain developmental aberrations in plant hybrids. In our theory, hybrid incompatibilities arise from imbalances in the mechanisms that cause male sterility in hermaphroditic plants. Mitochondria often cause male sterility by killing the tapetal tissue that nurtures pollen mother cells. Recent evidence suggests that mitochondria destroy the tapetum by triggering standard pathways of programmed cell death. Some nuclear genotypes repress mitochondrial male sterility and restore pollen fertility. Normal regulation of tapetal development therefore arises from a delicate balance between the disruptive effects of mitochondria and the defensive countermeasures of the nuclear genes. In hybrids, incompatibilities between male-sterile mitochondria and nuclear restorers may frequently upset the regulatory control of programmed cell death, causing tapetal abnormalities and male sterility. We propose that hybrid misregulation of programmed cell death may also spill over into other tissues, explaining various developmental aberrations observed in hybrids.

  19. BUS 620 ASHFORD Course Tutorial/TutorialRank

    OpenAIRE

    atwater

    2015-01-01

    For more course tutorials visit www.tutorialrank.com Tutorial Purchased: 4 Times, Rating: A   ASHFORD BUS 620 Week 1 DQ 1 What is Marketing   ASHFORD BUS 620 Week 1 DQ 2 Marketing Strategies   ASHFORD BUS 620 Week 1 Assignment Tesco Case   ASHFORD BUS 620 Week 2 DQ 1 Buyer Behavior   ASHFORD BUS 620 Week 2 DQ 2 Customer Needs   ASHFORD BUS 620 Week 2 Industry Forecasting   ASHFORD BUS 620 Week 3...

  20. BUS 660 ASHFORD Course Tutorial/TutorialRank

    OpenAIRE

    john

    2015-01-01

    For more course tutorials visit www.tutorialrank.com Tutorial Purchased: 4 Times, Rating: A+   BUS 660 Week 1 Assignment Developing Leaders at UPS  BUS 660 Week 2 Assignment Leadership Style  BUS 660 Week 3 Assignment Leadership Traits  BUS 660 Week 4 Assignment Leadership Skills  BUS 660 Week 5 Assignment Big Changes for a Small Hospital  BUS 660 Week 6 Assignment Research Paper BUS 660 Week 1 DQ 1Leadership Defined BU...

  1. PinBus Interface Design

    Energy Technology Data Exchange (ETDEWEB)

    Hammerstrom, Donald J.; Adgerson, Jewel D.; Sastry, Chellury; Pratt, Richard M.; Pratt, Robert G.

    2009-12-30

    On behalf of the U.S. Department of Energy, PNNL has explored and expanded upon a simple control interface that might have merit for the inexpensive communication of smart grid operational objectives (demand response, for example) to small electric end-use devices and appliances. The approach relies on bi-directional communication via the electrical voltage states of from one to eight shared interconnection pins. The name PinBus has been suggested and adopted for the proposed interface protocol. The protocol is defined through the presentation of state diagrams and the pins’ functional definitions. Both simulations and laboratory demonstrations are being conducted to demonstrate the elegance and power of the suggested approach. PinBus supports a very high degree of interoperability across its interfaces, allowing innumerable pairings of devices and communication protocols and supporting the practice of practically any smart grid use case.

  2. New TPG bus route 28

    CERN Multimedia

    2003-01-01

    Geneva's Public Transport services (TPG) have recently inaugurated a new bus line 28, connecting the La Tour Hospital in Meyrin to the international organisations in Geneva, via the airport. All signs associated with this route will be yellow in colour. Timetables and route details can be found at http://www.tpg.ch. Relations with the Host States Service http://www.cern.ch/relations/ Tel. 72848

  3. Programmed cell death in cereal aleurone.

    Science.gov (United States)

    Fath, A; Bethke, P; Lonsdale, J; Meza-Romero, R; Jones, R

    2000-10-01

    Progress in understanding programmed cell death (PCD) in the cereal aleurone is described. Cereal aleurone cells are specialized endosperm cells that function to synthesize and secrete hydrolytic enzymes that break down reserves in the starchy endosperm. Unlike the cells of the starchy endosperm, aleurone cells are viable in mature grain but undergo PCD when germination is triggered or when isolated aleurone layers or protoplasts are incubated in gibberellic acid (GA). Abscisic acid (ABA) slows down the process of aleurone cell death and isolated aleurone protoplasts can be kept alive in media containing ABA for up to 6 months. Cell death in barley aleurone occurs only after cells become highly vacuolated and is manifested in an abrupt loss of plasma membrane integrity. Aleurone cell death does not follow the apoptotic pathway found in many animal cells. The hallmarks of apoptosis, including internucleosomal DNA cleavage, plasma membrane and nuclear blebbing and formation of apoptotic bodies, are not observed in dying aleurone cells. PCD in barley aleurone cells is accompanied by the accumulation of a spectrum of nuclease and protease activities and the loss of organelles as a result of cellular autolysis.

  4. Bus Routes, Marta Bus Routes located in Transportation database, Published in unknown, City of Roswell, GA.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Bus Routes dataset as of unknown. It is described as 'Marta Bus Routes located in Transportation database'. Data by this publisher are often provided in State...

  5. YUTONG BUS: Grateful To The Financial Crisis

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Shenyin&Wanguo Securities issued an announcement on Jan 9 rating Yutong Bus(600066)as"buying",on the basis that the bus maker's gross profits went better in the last quarter of 2008 and to be further improved in the first quarter of 2009,with an increased market share. The report drew attention inside the in- dustry when the entire bus segment was suffering a tough time.

  6. Wishbone Bus Architecture - A Survey and Comparison

    Directory of Open Access Journals (Sweden)

    Mohandeep Sharma

    2012-05-01

    Full Text Available The performance of an on-chip interconnection architecture used for communication between IP cores depends on the efficiency of its bus architecture. Any bus architecture having advantages of faster bus clock speed, extra data transfer cycle, improved bus width and throughput is highly desirable for a low cost, reduced time-to-market and efficient System-on-Chip (SoC. This paper presents a survey of WISHBONE bus architecture and its comparison with three other on-chip bus architectures viz. Advanced Microcontroller Bus Architecture (AMBA by ARM, CoreConnect by IBM and Avalon by Altera. The WISHBONE Bus Architecture by Silicore Corporation appears to be gaining an upper edge over the other three bus architecture types because of its special performance parameters like the use of flexible arbitration scheme and additional data transfer cycle (Read-Modify-Write cycle. Moreover, its IP Cores are available free for use requiring neither any registration nor any agreement or license.

  7. Bus bar electrical feedthrough for electrorefiner system

    Science.gov (United States)

    Williamson, Mark; Wiedmeyer, Stanley G; Willit, James L; Barnes, Laurel A; Blaskovitz, Robert J

    2013-12-03

    A bus bar electrical feedthrough for an electrorefiner system may include a retaining plate, electrical isolator, and/or contact block. The retaining plate may include a central opening. The electrical isolator may include a top portion, a base portion, and a slot extending through the top and base portions. The top portion of the electrical isolator may be configured to extend through the central opening of the retaining plate. The contact block may include an upper section, a lower section, and a ridge separating the upper and lower sections. The upper section of the contact block may be configured to extend through the slot of the electrical isolator and the central opening of the retaining plate. Accordingly, relatively high electrical currents may be transferred into a glovebox or hot-cell facility at a relatively low cost and higher amperage capacity without sacrificing atmosphere integrity.

  8. Programming Surface Chemistry with Engineered Cells.

    Science.gov (United States)

    Zhang, Ruihua; Heyde, Keith C; Scott, Felicia Y; Paek, Sung-Ho; Ruder, Warren C

    2016-09-16

    We have developed synthetic gene networks that enable engineered cells to selectively program surface chemistry. E. coli were engineered to upregulate biotin synthase, and therefore biotin synthesis, upon biochemical induction. Additionally, two different functionalized surfaces were developed that utilized binding between biotin and streptavidin to regulate enzyme assembly on programmable surfaces. When combined, the interactions between engineered cells and surfaces demonstrated that synthetic biology can be used to engineer cells that selectively control and modify molecular assembly by exploiting surface chemistry. Our system is highly modular and has the potential to influence fields ranging from tissue engineering to drug development and delivery.

  9. Tubular solid oxide fuel cell development program

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-08-01

    This paper presents an overview of the Westinghouse Solid Oxide Fuel Cell (SOFC) development activities and current program status. The Westinghouse goal is to develop a cost effective cell that can operate for 50,000 to 100,000 hours. Progress toward this goal will be discussed and test results presented for multiple single cell tests which have now successfully exceeded 56,000 hours of continuous power operation at temperature. Results of development efforts to reduce cost and increase power output of tubular SOFCs are described.

  10. The Metabolic Syndrome and its Association with Over Time Driving in Iranian Professional Bus Drivers

    OpenAIRE

    Afshin Blouri; Ali Saba; Amin Shirazi; Farnaz Nabizadeh; Maghsoud Matinkhah; Iraj Mohebbi

    2010-01-01

    The aim of the study was to determine the prevalence of metabolic syndrome (MeS) in professional bus drivers, and its association with overtime working hours among those drivers in Urmia, Iran. In this cross sectional study the studies population was 626 professional bus drivers, aged 20-69 yr. The MeS (according to the National Cholesterol Education Program Adult Treatment Panel III), Waist circumference, Systolic blood pressure, Diastolic blood pressure, Fasting plasma glucose, Triglyceride...

  11. Virtual Instrument Based on GPIB Interface Bus1

    Institute of Scientific and Technical Information of China (English)

    Xiao,Ying; Qi,Hanhong

    2004-01-01

    In this paper, we introduced the technique of GPIB businterface. Through the controlling of the GPIB interface board,the computer controlled the current source and the voltmeter, both of which have GPIB bus interface, and a virtual instrument testing system for I~V curve was composed. The virtual instrument front panel and the background graphical control program in Labview environment accomplish virtual instrument testing task along with the hardware system.

  12. An Electric Bus with a Battery Exchange System

    OpenAIRE

    Jeongyong Kim; Inho Song; Woongchul Choi

    2015-01-01

    As part of the ongoing effort to be independent of petroleum resources and to be free from pollutant emission issues, various electric vehicles have been developed and tested through their integration with real world systems. In the current paper, yet another application specific EV for public transportation, an electric bus, is introduced and explained with results from the pilot test program which was carried out under real traffic conditions. The main feature of the current system is a bat...

  13. A new bus lane on urban expressway with no-bay bus stop

    Science.gov (United States)

    Tian, Zhao; Jia, Limin

    2016-01-01

    The sharp increase in residents and vehicles causes heavy traffic pressure in many cities. To ease traffic congestion, it has been the common sense that we should develop public transit system. The priority of the bus appears particularly necessary with the rapid development of the public transport system. The bus lane is an important embodiment of the bus priority. Focusing on the problem of the unreasonable dedicated bus lane (DBL) under the lower ratio of buses, this paper proposed a new bus lane with limited physical length. And this bus lane can reduce the lane-changing conflict caused by the buses and cars running on roads without bus lanes. Based on the cellular automata (CA) traffic flow model and the lane-changing behavior of the vehicle including the optional lane-changing and the mandatory lane-changing, a three-lane traffic model with an isolated no-bay bus stop is proposed. The ordinary three-lane traffic without a bus lane and the cases of traffic with a DBL or the proposed bus lane are simulated, and the comparisons in the form of the fundamental diagrams are made among them. It is shown that the no-bay bus stop can act as a bottleneck on the traffic flow because of the mandatory lane-changing behavior. Under a certain ratio of the bus number to the total vehicles number, (1) the traffic with the proposed bus lane has less lane-changing conflict and can provide higher traffic capacity than the ordinary traffic without a bus lane, (2) compared with the DBL, the proposed bus lane is advantageous in easing congestion on the ordinary lanes when the traffic flow is high and can avoid unreasonable allocation of the road resources.

  14. Chrysler Pentastar direct hydrogen fuel cell program

    Energy Technology Data Exchange (ETDEWEB)

    Kimble, M.; Deloney, D.

    1995-08-01

    The Chrysler Pentastar Electronics, Inc. Direct Hydrogen Fueled PEM Fuel Cell Hybrid Vehicle Program (DPHV) was initiated 1 July, 1994 with the following mission, {open_quotes}Design, fabricate, and test a Direct Hydrogen Fueled Proton Exchange Membrane (PEM) Fuel Cell System including onboard hydrogen storage, an efficient lightweight fuel cell, a gas management system, peak power augmentation and a complete system controls that can be economically mass produced and comply with all safety environmental and consumer requirements for vehicle applications for the 21st century.{close_quotes} The Conceptual Design for the entire system based upon the selection of an applicable vehicle and performance requirements that are consistent with the PNGV goals will be discussed. A Hydrogen Storage system that has been selected, packaged, and partially tested in accordance with perceived Hydrogen Safety and Infrastructure requirements will be discussed in addition to our Fuel Cell approach along with design of the {open_quotes}real{close_quotes} module. The Gas Management System and the Load Leveling System have been designed and the software programs have been developed and will be discussed along with a complete fuel cell test station that has the capability to test up to a 60 kW fuel cell system.

  15. Implementation of an AMBA Advanced High Performance Bus protocol IP block

    Directory of Open Access Journals (Sweden)

    Mahendra Vucha Sandeep Magarde

    2011-08-01

    Full Text Available The design of an AMBA advanced high performance bus (AHB protocol IP block is presented in this paper. The AHB (Advanced High-performance Bus is a high-performance bus in AMBA (Advanced Microcontroller Bus Architecture family. This AHB can be used in high clock frequency system modules. The AHB acts as the high-performance system backbone bus. AHB supports the efficient connection of processors, on-chip memories and off-chip external memory interfaces with low-power peripheral macro cell functions. In this work, the design of the Advanced High-Performance Bus Protocol is developed which has the basic blocks such as Master and Slave. The arbitration mechanism is used to ensure that only one master has access to the bus at any one time and the AHB decoder is used to decode the address of each transfer and provide a select signal for the slave that is involved in the transfer. This AMBA-AHB protocol can be adopted in all the application provided the design should be an AHB compliant.

  16. Mastering NServiceBus and persistence

    CERN Document Server

    Helton, Rich

    2014-01-01

    This book is intended for developers, designers, and architects alike who wish to build C# NServiceBus enterprise architectures and learn how ESB persists data and messages to help them attain their goals. No prior knowledge of persistence in NServiceBus is required.

  17. DOE Hydrogen and Fuel Cells Program Plan (September 2011)

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2011-09-01

    The Department of Energy Hydrogen and Fuel Cells Program Plan outlines the strategy, activities, and plans of the DOE Hydrogen and Fuel Cells Program, which includes hydrogen and fuel cell activities within the EERE Fuel Cell Technologies Program and the DOE offices of Nuclear Energy, Fossil Energy, and Science.

  18. Fiscal 1999 report on basic research for promotion of joint implementation programs. Research on introduction of dual mode bus system for greenhouse gas reduction; 1999 nendo onshitsu koka gas sakugen no tame no dual mode bus system donyu ni kansuru chosa hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    A feasibility study is conducted of the above-named system in Malaysia, to be linked to COP3 (Third Session of the Conference of the Parties to the United Nations Framework Convention on Climate Change) clean development mechanism (CDM). The dual mode bus system (DMBS) is a combination of advantages of the rail running stock such as monorails and the road running stock in that the buses when running on dedicated roads are automatedly formed into a linear formation and travel at a specified economical speed. When running on ordinary roads, the formation is broken into individual buses, and they spread in the town where they travel in a planar pattern. The economical speed and reduction in air drag thanks to the linear formation saves fuel and reduces CO2 emissions. The complementary relationship to be formed with the existing public transportation systems will also function positively. Studies are conducted on condition that two routes be laid in the Kuala Lumpur urban area and one in the new city Putra Jaya. All the three routes exhibit a high economic internal rate of return, but their financial internal rate of return indicates that probabilities are low that they will pay as private businesses. They will need financial supports such as subsidies. Contribution to CO2 reduction may be slight when attention is paid only to the partial changeover from the existing bus system to DMBS but larger contribution will be found in crossover from private cars to DMBS which is higher in quality of service. (NEDO)

  19. US Polycrystalline Thin Film Solar Cells Program

    Science.gov (United States)

    Ullal, Harin S.; Zweibel, Kenneth; Mitchell, Richard L.

    1989-11-01

    The Polycrystalline Thin Film Solar Cells Program, part of the United States National Photovoltaic Program, performs R and D on copper indium diselenide and cadmium telluride thin films. The objective of the program is to support research to develop cells and modules that meet the U.S. Department of Energy's long-term goals by achieving high efficiencies (15 to 20 percent), low-cost ($50/m(sup 2)), and long-time reliability (30 years). The importance of work in this area is due to the fact that the polycrystalline thin-film CuInSe2 and CdTe solar cells and modules have made rapid advances. They have become the leading thin films for PV in terms of efficiency and stability. The U.S. Department of Energy has increased its funding through an initiative through the Solar Energy Research Institute in CuInSe2 and CdTe with subcontracts to start in spring 1990.

  20. US polycrystalline thin film solar cells program

    Energy Technology Data Exchange (ETDEWEB)

    Ullal, H S; Zweibel, K; Mitchell, R L [Solar Energy Research Inst., Golden, CO (USA)

    1989-11-01

    The Polycrystalline Thin Film Solar Cells Program, part of the United States National Photovoltaic Program, performs R D on copper indium diselenide and cadmium telluride thin films. The objective of the Program is to support research to develop cells and modules that meet the US Department of Energy's long-term goals by achieving high efficiencies (15%-20%), low-cost ($50/m{sup 2}), and long-time reliability (30 years). The importance of work in this area is due to the fact that the polycrystalline thin-film CuInSe{sub 2} and CdTe solar cells and modules have made rapid advances. They have become the leading thin films for PV in terms of efficiency and stability. The US Department of Energy has increased its funding through an initiative through the Solar Energy Research Institute in CuInSe{sub 2} and CdTe with subcontracts to start in Spring 1990. 23 refs., 5 figs.

  1. Market brief : the alternative fuels bus market in India

    International Nuclear Information System (INIS)

    In 2003, alternative fuel bus technologies in India were valued at approximately $1.5 billion. There are an estimated 600,000 buses in India, of which 21 per cent are owned by public transit. Bus production is currently 33,000 per year and increasing at 4 per cent annually. The main alternative fuel bus technologies include fuel cells, compressed natural gas (CNG) and liquefied petroleum gas (LPG). Since urban centres in India are among the most polluted in the world, demand for these technologies is strong. India is ranked fifth in the world in terms of vehicles converted to natural gas. In 2003, New Delhi switched from diesel to CNG fuel for buses but has faced challenges because there is no well-developed underground distribution system and refilling times are long due to weak pressure at fueling stations. India's new $28 million fuel cell bus development project aims to place 8 fuel cell powered buses with the Delhi Transport Corporation. This market brief describes the potential for Canadian suppliers to enter into joint ventures to establish local production facilities and transfer technology expertise. It describes the key factors shaping market growth with particular reference to sector reform, and opportunities with actual and planned projects. The competitive environment was also discussed with reference to local capabilities, international competition, Canadian position, and a competitive advantage through Canadian government policies and initiatives. A section of the report on public-sector customers listed the companies that buy alternative fuel buses in India. Considerations for market-entry in India were also outlined

  2. Simulation of Organic Solar Cells Using AMPS-1D Program

    Directory of Open Access Journals (Sweden)

    Samah G. Babiker

    2012-03-01

    Full Text Available The analysis of microelectronic and photonic structure in one dimension program [AMPS-1D] program has been successfully used to study inorganic solar cells. In this work the program has been used to optimize the performance of the organic solar cells. The cells considered consist of poly(2-methoxy-5-(3,7- dimethyloctyloxy-1,4-phenylenevinylene [MDMO-PPV

  3. Research and development of a phosphoric acid fuel cell/battery power source integrated in a test-bed bus. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-05-30

    This project, the research and development of a phosphoric acid fuel cell/battery power source integrated into test-bed buses, began as a multi-phase U.S. Department of Energy (DOE) project in 1989. Phase I had a goal of developing two competing half-scale (25 kW) brassboard phosphoric acid fuel cell systems. An air-cooled and a liquid-cooled fuel cell system were developed and tested to verify the concept of using a fuel cell and a battery in a hybrid configuration wherein the fuel cell supplies the average power required for operating the vehicle and a battery supplies the `surge` or excess power required for acceleration and hill-climbing. Work done in Phase I determined that the liquid-cooled system offered higher efficiency.

  4. Radiation-Tolerant Dual Data Bus

    Science.gov (United States)

    Kinstler, Gary A.

    2007-01-01

    An architecture, and a method of utilizing the architecture, have been proposed to enable error-free operation of a data bus that includes, and is connected to, commercial off-the-shelf (COTS) circuits and components that are inherently susceptible to singleevent upsets [SEUs (bit flips caused by impinging high-energy particles and photons)]. The architecture and method are applicable, more specifically, to data-bus circuitry based on the Institute for Electrical and Electronics Engineers (IEEE) 1394b standard for a high-speed serial bus.

  5. Drivetrain system of an ultracapacitor electric bus

    Institute of Scientific and Technical Information of China (English)

    Kong Zhigu; Zhu Chunbo; Yang Shiyan; Cheng Shukang

    2007-01-01

    This paper proposed a design of the drivetrain system of an electric bus with ultracapacitor (UC) as the only on-board power source. The system includes three main parts, namely, UC bank, motor and the converter, vehicle management unit (VMU). Analyses results in detail on the functional design and experiments on work bench of each part were also presented, which validated the reliability of the system. Furthermore, driving results in field of the bus verified the feasibility of the design of the drivetrain system. The bus has very good dynamic performances and shows a promising applications prospect in the short and medium route buses system.

  6. BUS 1000母线保护的应用%Application of BUS 1000 Bus-Bar Protection

    Institute of Scientific and Technical Information of China (English)

    马晓光; 张贵金; 冷雪玉

    2001-01-01

    发电厂的母线是电厂中的一个重要组成元件,当母线上发生故障时,将使连接在故障母线上的所有元件在修复故障母线期间,或转换到另一组母线上运行以前遭到停电。同时还可能破坏系统稳定,造成严重后果。因此,母线保护装置是正确迅速切除母线故障的重要装置,它的拒动或误动将给电力系统带来严重危害。详细介绍了华能丹东发电厂350 MW发电机组采用的BUS 1000型母线保护的原理,并对其正常运行及区内、外故障、断路器失灵保护、母联断路器过流保护等几个方面作了详细分析。%Bus bar is an important component in e lectric power plant.When bus bar fault occurs,all components connected on the fa ulty bus bar will be in outage until power restores by repairing the faulty bus bar or switching them over to another bus bar.Furthermore,it may cause the destr uction of system stability resulting in serious consequence.Bus bar protection d evice is the very device to quickly remove bus bar faults,and its malfunctioning will bring serious harm to power system. The principle of BUS 1000 bus bar prot ection used for 350 MW unit of dandong power plant is introduced.Its normal oper ation and several aspects,such as in-and out-area faults,out-of-order breake r protection,bus bar breaker over-current protection,are analyzed in detail.

  7. An analytical algorithm to determine allowable ampacities of horizontally installed rectangular bus bars

    Directory of Open Access Journals (Sweden)

    Klimenta Dardan O.

    2016-01-01

    Full Text Available The main objective of this paper is to propose an algorithm for the determination of the allowable ampacities of single rectangular-section bus bars without the occurrence of correction factors. Without correction factors, the ampacity computation of the copper and aluminium bus bars is fully automatized. The analytical algorithm has been implemented in a computer program code that along with the allowable ampacity can compute the bus bar temperature and the individual heat transfer coefficient for each side of the bus bar, as well as their corresponding power losses. Natural and forced convection correlations for rectangular bus bars are applied. Effects of the solar radiation and radiation heat losses from the bus bar surface are taken into consideration as well. The finite element method (FEM has been used for the linear/non-linear steady-state thermal analysis, i.e. for validation of the analytical algorithm. All FEM-based numerical computations were carried out using the COMSOL Heat Transfer Module. [Projekat Ministarstva nauke Republike Srbije, br. TR33046

  8. Exact and Metaheuristic Approaches for a Bi-Objective School Bus Scheduling Problem.

    Science.gov (United States)

    Chen, Xiaopan; Kong, Yunfeng; Dang, Lanxue; Hou, Yane; Ye, Xinyue

    2015-01-01

    As a class of hard combinatorial optimization problems, the school bus routing problem has received considerable attention in the last decades. For a multi-school system, given the bus trips for each school, the school bus scheduling problem aims at optimizing bus schedules to serve all the trips within the school time windows. In this paper, we propose two approaches for solving the bi-objective school bus scheduling problem: an exact method of mixed integer programming (MIP) and a metaheuristic method which combines simulated annealing with local search. We develop MIP formulations for homogenous and heterogeneous fleet problems respectively and solve the models by MIP solver CPLEX. The bus type-based formulation for heterogeneous fleet problem reduces the model complexity in terms of the number of decision variables and constraints. The metaheuristic method is a two-stage framework for minimizing the number of buses to be used as well as the total travel distance of buses. We evaluate the proposed MIP and the metaheuristic method on two benchmark datasets, showing that on both instances, our metaheuristic method significantly outperforms the respective state-of-the-art methods. PMID:26176764

  9. Exact and Metaheuristic Approaches for a Bi-Objective School Bus Scheduling Problem.

    Directory of Open Access Journals (Sweden)

    Xiaopan Chen

    Full Text Available As a class of hard combinatorial optimization problems, the school bus routing problem has received considerable attention in the last decades. For a multi-school system, given the bus trips for each school, the school bus scheduling problem aims at optimizing bus schedules to serve all the trips within the school time windows. In this paper, we propose two approaches for solving the bi-objective school bus scheduling problem: an exact method of mixed integer programming (MIP and a metaheuristic method which combines simulated annealing with local search. We develop MIP formulations for homogenous and heterogeneous fleet problems respectively and solve the models by MIP solver CPLEX. The bus type-based formulation for heterogeneous fleet problem reduces the model complexity in terms of the number of decision variables and constraints. The metaheuristic method is a two-stage framework for minimizing the number of buses to be used as well as the total travel distance of buses. We evaluate the proposed MIP and the metaheuristic method on two benchmark datasets, showing that on both instances, our metaheuristic method significantly outperforms the respective state-of-the-art methods.

  10. On-Orbit Demonstration Of Thin-Film Multi-Junction Solar Cells And Lithium-Ion Capacitors As Bus Components

    Science.gov (United States)

    Kukita, Akio; Takahashi, Masato; Shimazaki, Kazunori; Toyota, Hiroyuki; Imaizumi, Mitsuru; Kobayashi, Yuki; Takamoto, Tatsuya; Uno, Masatoshi; Shimada, Takanobu

    2011-10-01

    This paper describes an on-orbit demonstration plan for a lightweight solar panel using thin-film multi-junction (MJ) solar cells and aluminum-laminated lithium-ion capacitors (LICs). Thin-film MJ solar cells such as inverted metamorphic InGaP/GaAs/InGaAs 3J cells have flexibility as well as conversion efficiencies superior to conventional rigid 3J solar cells. A substantial reduction of satellite mass is achieved by the combination of thin-film MJ solar cells and light flexible paddles. An LIC is a hybrid-type capacitor that uses activated carbon as the cathode and carbon material pre-doped with lithium ion as the anode. LICs can be rapidly charged and discharged, and can operate in a wide temperature range for long periods. LICs are therefore suitable for long-term missions such as planetary explorations. Although these devices are very promising, so far there has been no opportunity to demonstrate their use in orbit. A lightweight thin solar panel with thin-film MJ solar cells will be installed on the Small Scientific Satellite Platform for Rapid Investigation and Test-A (SPRINT-A) satellite, which will be launched on the Epsilon launch vehicle in 2013. Utilizing the capacitor-like voltage behavior of LICs, we will employ a simple constant-power charging circuit without feedback control.

  11. Calculation of Flexible Bus-Bars Electrodynamic Stability with Application of Implicit Scheme

    Directory of Open Access Journals (Sweden)

    Y. G. Panamarenka

    2008-01-01

    Full Text Available A numerical method for calculation of open-air substations’ flexible bus-bars dynamic at short-circuit has been improved on equations of a flexible elastic string with application of an implicit scheme. On the basis of the numerical method a computer program FLEBUS for calculation of substations’ flexible bus-bars dynamic at short-circuit has been developed. An approbation and an estimation of calculation result reliability have been carried out in accordance with the program while using experimental data. On the basis of the obtained information it is possible to assert that the developed program is an independent tool for calculation of electrodynamic stability of substations’ flexible bus-bars.

  12. The AI Bus architecture for distributed knowledge-based systems

    Science.gov (United States)

    Schultz, Roger D.; Stobie, Iain

    1991-01-01

    The AI Bus architecture is layered, distributed object oriented framework developed to support the requirements of advanced technology programs for an order of magnitude improvement in software costs. The consequent need for highly autonomous computer systems, adaptable to new technology advances over a long lifespan, led to the design of an open architecture and toolbox for building large scale, robust, production quality systems. The AI Bus accommodates a mix of knowledge based and conventional components, running on heterogeneous, distributed real world and testbed environment. The concepts and design is described of the AI Bus architecture and its current implementation status as a Unix C++ library or reusable objects. Each high level semiautonomous agent process consists of a number of knowledge sources together with interagent communication mechanisms based on shared blackboards and message passing acquaintances. Standard interfaces and protocols are followed for combining and validating subsystems. Dynamic probes or demons provide an event driven means for providing active objects with shared access to resources, and each other, while not violating their security.

  13. An Electric Bus with a Battery Exchange System

    Directory of Open Access Journals (Sweden)

    Jeongyong Kim

    2015-07-01

    Full Text Available As part of the ongoing effort to be independent of petroleum resources and to be free from pollutant emission issues, various electric vehicles have been developed and tested through their integration with real world systems. In the current paper, yet another application specific EV for public transportation, an electric bus, is introduced and explained with results from the pilot test program which was carried out under real traffic conditions. The main feature of the current system is a battery exchanging mechanism mounted on the roof of the bus. The current configuration certainly requires an externally fabricated battery exchanging robot system that would complement the electric bus for a fully automated battery exchanging process. The major advantage of the current system is the quick re-charging of the electric energy through the physical battery exchange and the possible utilization of the battery exchange station as a mini scale energy storage system for grid system peak power shaving. With the total system solution approach for the public transportation system, it is fully expected to create outstanding business opportunities in number of areas such as battery suppliers, battery exchanging station management, battery leasing and many more.

  14. Incremental bus service design: combining limited-stop and local bus services

    OpenAIRE

    Chiraphadhanakul, Virot; Barnhart, Cynthia

    2013-01-01

    Long in-vehicle travel times resulting from frequent stops make bus service an unattractive choice for many commuters. Limited-stop bus services however have the advantage of shorter in-vehicle times experienced by passengers. In this work, we seek to modify a given bus service by optimally reassigning some number of bus trips, as opposed to providing additional trips, to operate a limited-stop service. We propose an optimization model to determine a limited-stop service route to be operated ...

  15. BUS 599 STRAYER Course Tutorial/TutorialRank

    OpenAIRE

    alfonos

    2015-01-01

    For more course tutorials visit www.tutorialrank.com Tutorial Purchased: 4 Times, Rating: A+ STRAYER BUS 599 Week 1 Assignment Crafting and Executing Strategy Case JetBlue Airways STRAYER BUS 599 Week 2 Assignment Competitive Forces and SWOT Analysis Case Whole Foods Market STRAYER BUS 599 Week 3 Assignment Foreign Market Entry and Diversification Case Corona Beer STRAYER BUS 599 Week 4 Assignment HRM Issues Diversification Strategies Case Nucor Corporation STRAYER BUS 5...

  16. DESIGN AND EXPERIMENT OF ELECTRIC BUS

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    Performance and reliability experiments on BJD-6100EV electric buses, jointly developed by Beijing Institute of Technology and Beijing Public Transport Company, are introduced. Output power model of battery pack is established and maximum output power is analyzed. A permanent magnetic direct current (PMDC) motor with enhanced windings is developed for the bus. Torque-speed characteristics of the motor are modeled and performance of electric bus is analyzed. Computational method of the range of electric bus is proposed and discussed. Experiments show that electric bus can realize design requirements. Computational methods are verified with the help of field test. It is expected that design and computation method will provide helpful reference to development of electric vehicles.

  17. Programmed cell death in plants and caspase-like activities

    NARCIS (Netherlands)

    Gaussand, Gwénael Martial Daniel Jean-Marie

    2007-01-01

    The development of multicellular organisms involves an important balance between cell growth, cell division and cell death. In animals, programmed cell death (PCD) plays a key role by forming and deleting structures, controlling cell numbers and eliminating abnormal damaged cells. Caspases were foun

  18. Systems evaluation of thermal bus concepts

    Science.gov (United States)

    Stalmach, D. D.

    1982-01-01

    Thermal bus concepts, to provide a centralized thermal utility for large, multihundred kilowatt space platforms, were studied and the results are summarized. Concepts were generated, defined, and screened for inclusion in system level thermal bus trades. Parametric trade studies were conducted in order to define the operational envelope, performance, and physical characteristics of each. Two concepts were selected as offering the most promise for thermal bus development. All of four concepts involved two phase flow in order to meet the required isothermal nature of the thermal bus. Two of the concepts employ a mechanical means to circulate the working fluid, a liquid pump in one case and a vapor compressor in another. Another concept utilizes direct osmosis as the driving force of the thermal bus. The fourth concept was a high capacity monogroove heat pipe. After preliminary sizing and screening, three of these concepts were selected to carry into the trade studies. The monogroove heat pipe concept was deemed unsuitable for further consideration because of its heat transport limitations. One additional concept utilizing capillary forces to drive the working fluid was added. Parametric system level trade studies were performed. Sizing and weight calculations were performed for thermal bus sizes ranging from 5 to 350 kW and operating temperatures in the range of 4 to 120 C. System level considerations such as heat rejection and electrical power penalties and interface temperature losses were included in the weight calculations.

  19. Acetylsalicylic acid induces programmed cell death in Arabidopsis cell cultures.

    Science.gov (United States)

    García-Heredia, José M; Hervás, Manuel; De la Rosa, Miguel A; Navarro, José A

    2008-06-01

    Acetylsalicylic acid (ASA), a derivative from the plant hormone salicylic acid (SA), is a commonly used drug that has a dual role in animal organisms as an anti-inflammatory and anticancer agent. It acts as an inhibitor of cyclooxygenases (COXs), which catalyze prostaglandins production. It is known that ASA serves as an apoptotic agent on cancer cells through the inhibition of the COX-2 enzyme. Here, we provide evidences that ASA also behaves as an agent inducing programmed cell death (PCD) in cell cultures of the model plant Arabidopsis thaliana, in a similar way than the well-established PCD-inducing agent H(2)O(2), although the induction of PCD by ASA requires much lower inducer concentrations. Moreover, ASA is herein shown to be a more efficient PCD-inducing agent than salicylic acid. ASA treatment of Arabidopsis cells induces typical PCD-linked morphological and biochemical changes, namely cell shrinkage, nuclear DNA degradation, loss of mitochondrial membrane potential, cytochrome c release from mitochondria and induction of caspase-like activity. However, the ASA effect can be partially reverted by jasmonic acid. Taking together, these results reveal the existence of common features in ASA-induced animal apoptosis and plant PCD, and also suggest that there are similarities between the pathways of synthesis and function of prostanoid-like lipid mediators in animal and plant organisms.

  20. Programmed Cell Death in Unicellular Phytoplankton.

    Science.gov (United States)

    Bidle, Kay D

    2016-07-11

    Unicellular, planktonic, prokaryotic and eukaryotic photoautotrophs (phytoplankton) have an ancient evolutionary history on Earth during which time they have played key roles in the regulation of marine food webs, biogeochemical cycles, and Earth's climate. Since they represent the basis of aquatic ecosystems, the manner in which phytoplankton die critically determines the flow and fate of photosynthetically fixed organic matter (and associated elements), ultimately constraining nutrient flow. Programmed cell death (PCD) and associated pathway genes, which are triggered by a variety of abiotic (nutrient, light, osmotic) and biotic (virus infection, allelopathy) environmental stresses, have an integral grip on cell fate, and have shaped the ecological success and evolutionary trajectory of diverse phytoplankton lineages. A combination of physiological, biochemical, and genetic techniques in model algal systems has demonstrated a conserved molecular and mechanistic framework of stress surveillance, signaling, and death activation pathways, involving collective and coordinated participation of organelles, redox enzymes, metabolites, and caspase-like proteases. This mechanistic understanding has provided insight into the integration of sensing and transduction of stress signals into cellular responses, and the mechanistic interfaces between PCD, cell stress and virus infection pathways. It has also provided insight into the evolution of PCD in unicellular photoautotrophs, the impact of PCD on the fate of natural phytoplankton assemblages and its role in aquatic biogeochemical cycles. PMID:27404255

  1. Life cycle cost analysis of a car, a city bus and an intercity bus powertrain for year 2005 and 2020

    International Nuclear Information System (INIS)

    The international economy, in the beginning of the 20th century, is characterized by uncertainty about the supply and the price of oil. Together with the fast decrease of electrical propulsion component prices, it becomes more and more cost effective to develop vehicles with alternative powertrains. This paper focuses on two questions: Are alternative powertrains especially cost effective for specific applications?; How does an increased fossil fuel price influences the choose of powertrain? To assess these questions, a computer tool named THEPS, developed in a Ph.D. project, is used. Three applications and three scenarios are analysed. The applications, a car, a city bus and an intercity bus, are vehicles all assumed to operate in Sweden. One scenario represents year 2005, the other two year 2020. The two future scenarios are characterized by different fossil fuel prices. The study, presented in the paper, indicates that alternative powertrains can be competitive from a cost perspective, in some applications, already in year 2005. It is for example cost effective to equip a city bus, running in countries with a high fuel price, with a hybrid powertrain. The study also indicates that pure electric, hybrid and/or fuel cell cars will probably be a more cost effective choice than conventional cars in year 2020. Another indication is that it will not be clear which powertrain concept to choose. The reason is that many cost effective powertrain concepts will be offered. The best choice will depend on the application

  2. Development of an integrated cryogenic bus for spacecraft applications

    Science.gov (United States)

    Bugby, David C.; Brennan, Patrick J.; Davis, Thomas M.; Tomlinson, Joe; Stoyanof, Marko; Crawford, Larry; Glaister, David S.

    1997-01-01

    To improve the efficiency and reduce the overdesign penalties associated with integrating cryogenic systems into spacecraft, the Integrated Cryogenic Bus (ICB) program was initiated in April 1996. The technical objectives of the program were to develop an integrated, lightweight means of thermally linking a cryogenic cooling source to a cooled satellite component, to commonize the interfaces to the cooling source and cooled component, and to commonize the integration of these systems into spacecraft. The technical plan involves several steps beginning with the definition of requirements, the identification and characterization of potential bus components, the development of new concepts and optimization methods, breadboard testing, and prototype development. Six months into the program, over 25 cryocooler, focal plane, and cryogenic hardware organizations have been interviewed or surveyed to identify requirements, numerous components have been identified and characterized, several preliminary concepts have been developed, an optimization plan has been outlined, and critical breadboard tests have begun. This paper summarizes the progress to date during Phase I of this Phillips Laboratory program funded by the Ballistic Missile Defense Organization (BMDO).

  3. Design of belt conveyor electric control device based on CC-link bus

    Science.gov (United States)

    Chen, Goufen; Zhan, Minhua; Li, Jiehua

    2016-01-01

    In view of problem of the existing coal mine belt conveyor is no field bus communication function, two levels belt conveyor electric control system design is proposed based on field bus. Two-stage belt conveyor electric control system consists of operation platform, PLC control unit, various sensors, alarm device and the water spraying device. The error protection is realized by PLC programming, made use of CC-Link bus technology, the data share and the cooperative control came true between host station and slave station. The real-time monitor was achieved by the touch screen program. Practical application shows that the system can ensure the coalmine production, and improve the automatic level of the coalmine transport equipment.

  4. Dynamic Bus Travel Time Prediction Models on Road with Multiple Bus Routes.

    Science.gov (United States)

    Bai, Cong; Peng, Zhong-Ren; Lu, Qing-Chang; Sun, Jian

    2015-01-01

    Accurate and real-time travel time information for buses can help passengers better plan their trips and minimize waiting times. A dynamic travel time prediction model for buses addressing the cases on road with multiple bus routes is proposed in this paper, based on support vector machines (SVMs) and Kalman filtering-based algorithm. In the proposed model, the well-trained SVM model predicts the baseline bus travel times from the historical bus trip data; the Kalman filtering-based dynamic algorithm can adjust bus travel times with the latest bus operation information and the estimated baseline travel times. The performance of the proposed dynamic model is validated with the real-world data on road with multiple bus routes in Shenzhen, China. The results show that the proposed dynamic model is feasible and applicable for bus travel time prediction and has the best prediction performance among all the five models proposed in the study in terms of prediction accuracy on road with multiple bus routes.

  5. Sexual Harassment on the School Bus: Supporting and Preparing Bus Drivers to Respond Appropriately

    Science.gov (United States)

    Allen, Melissa; Young, Ellie L.; Ashbaker, Betty Y.; Heaton, Emily; Parkinson, Marisa

    2003-01-01

    Sexual harassment is commonplace in schools, particularly among adolescents. Although information on this topic is typically gathered from students and teachers, this study collected information from school bus drivers. Based on feedback from 58 school bus drivers, 39 (67%) reported observing students making sexual comments or jokes. Almost half…

  6. Bullying and Aggression on the School Bus: School Bus Drivers' Observations and Suggestions

    Science.gov (United States)

    deLara, Ellen

    2008-01-01

    Every school day bus drivers are responsible for transporting children safely over many miles, yet they are rarely polled for their opinions or contributions to school safety. School bus drivers are in a unique position to inform the discussion on aggressive behavior during the school day. This exploratory study collected information from school…

  7. Senescence and programmed cell death : substance or semantics?

    NARCIS (Netherlands)

    Doorn, van W.G.; Woltering, E.J.

    2004-01-01

    The terms senescence and programmed cell death (PCD) have led to some confusion. Senescence as visibly observed in, for example, leaf yellowing and petal wilting, has often been taken to be synonymous with the programmed death of the constituent cells. PCD also obviously refers to cells, which show

  8. Designing Bus Structure for Digital Controller of Nuclear Power Plant

    International Nuclear Information System (INIS)

    In this paper, the bus structure design for the digital controller of Nuclear Power Plant (NPP) is proposed. The most important portion is the bus in the digital controller. A bus is responsible for transmission data among the various Input/Output (I/O) board, Processor board and Communication board. An existing bus is a parallel bus structure such as the VERSA Module Euro (VME) bus and an extended Static Random Access Memory (SRAM) Controller. Central Processing Unit (CPU) processing speed and communication speed is faster than before, but the parallel bus has a speed limit. Because it is the physically lines shared and the weakness about reflected wave. That is, use of the parallel bus has been the cause of the performance degradation of system. To solve the parallel bus problem, the bus has been developed by serial. The configuration of transceiver logic was simplified by not share the bus that all boards and processor boards was connected to the point-to-point. Serial bus was configured using physically Low Voltage Differential Signaling (LVDS). The speed limit of bus was broken by the LVDS what is consisted of a strong against the reflected-wave of signal, noise and etc. Each channel of bus has a different speed mode and is able to set a required transmission way. Different transmission ways of each channel are able to transmit data to match the required response time of system. The LVDS speed has about basically 1Gbps but the bus was composed with less than 50Mbps considering the environmental characteristics of nuclear. It was shown that the configuration of the serial bus was the performance and the reliability more improving than parallel bus

  9. CELLFS: TAKING THE "DMA" OUT OF CELL PROGRAMMING

    Energy Technology Data Exchange (ETDEWEB)

    IONKOV, LATCHESAR A. [Los Alamos National Laboratory; MIRTCHOVSKI, ANDREY A. [Los Alamos National Laboratory; NYRHINEN, AKI M. [Los Alamos National Laboratory

    2007-01-09

    In this paper we present a new programming model for the Cell BE architecture of scalar multiprocessors. They call this programming model CellFS. CellFS aims at simplifying the task of managing I/O between the local store of the processing units and main memory. The CellFS support library provides the means for transferring data via simple file I/O operations between the PPU and the SPU.

  10. Programmed cell death in plants: A chloroplastic connection

    OpenAIRE

    Ambastha, Vivek; Tripathy, Baishnab C; Tiwari, Budhi Sagar

    2015-01-01

    Programmed cell death (PCD) is an integral cellular program by which targeted cells culminate to demise under certain developmental and pathological conditions. It is essential for controlling cell number, removing unwanted diseased or damaged cells and maintaining the cellular homeostasis. The details of PCD process has been very well elucidated and characterized in animals but similar understanding of the process in plants has not been achieved rather the field is still in its infancy that ...

  11. Statistical Analysis of Bus Networks in India

    CERN Document Server

    Chatterjee, Atanu; Ramadurai, Gitakrishnan

    2015-01-01

    Through the past decade the field of network science has established itself as a common ground for the cross-fertilization of exciting inter-disciplinary studies which has motivated researchers to model almost every physical system as an interacting network consisting of nodes and links. Although public transport networks such as airline and railway networks have been extensively studied, the status of bus networks still remains in obscurity. In developing countries like India, where bus networks play an important role in day-to-day commutation, it is of significant interest to analyze its topological structure and answer some of the basic questions on its evolution, growth, robustness and resiliency. In this paper, we model the bus networks of major Indian cities as graphs in \\textit{L}-space, and evaluate their various statistical properties using concepts from network science. Our analysis reveals a wide spectrum of network topology with the common underlying feature of small-world property. We observe tha...

  12. High speed data bus design validation

    Science.gov (United States)

    Stevens, Rick

    The SAE Linear Implementation Task Group has developed the SAE Linear Token Passing Multiplex Data Bus Standard (AS4074.1) and is currently working on a validation plan. This validation plan will define the test requirements for determining that an implementation of the standard meets the requirements of SAE AS4074.1. Once completed, the test requirements contained in this plan will be executed on bus interface units (BIUs) for validation purposes. In the present work, the author describes the use of a validation model that incorporates many of the capabilities of the validation test plan. This model can also be thought of as a VHDL (VHSIC Hardware Description Language) behavioral representation of the SAE Linear Token Passing Multiplex Data Bus Standard. It is tightly coupled to the standard and provides a model that can be used during the BIU development to validate the design.

  13. Risk factors affecting fatal bus accident severity: Their impact on different types of bus drivers.

    Science.gov (United States)

    Feng, Shumin; Li, Zhenning; Ci, Yusheng; Zhang, Guohui

    2016-01-01

    While the bus is generally considered to be a relatively safe means of transportation, the property losses and casualties caused by bus accidents, especially fatal ones, are far from negligible. The reasons for a driver to incur fatalities are different in each case, and it is essential to discover the underlying risk factors of bus fatality severity for different types of drivers in order to improve bus safety. The current study investigates the underlying risk factors of fatal bus accident severity to different types of drivers in the U.S. by estimating an ordered logistic model. Data for the analysis are retrieved from the Buses Involved in Fatal Accidents (BIFA) database from the USA for the years 2006-2010. Accidents are divided into three levels by counting their equivalent fatalities, and the drivers are classified into three clusters by the K-means cluster analysis. The analysis shows that some risk factors have the same impact on different types of drivers, they are: (a) season; (b) day of week; (c) time period; (d) number of vehicles involved; (e) land use; (f) manner of collision; (g) speed limit; (h) snow or ice surface condition; (i) school bus; (j) bus type and seating capacity; (k) driver's age; (l) driver's gender; (m) risky behaviors; and (n) restraint system. Results also show that some risk factors only have impact on the "young and elder drivers with history of traffic violations", they are: (a) section type; (b) number of lanes per direction; (c) roadway profile; (d) wet road surface; and (e) cyclist-bus accident. Notably, history of traffic violations has different impact on different types of bus drivers. PMID:26513334

  14. 77 FR 6172 - Discretionary Bus and Bus Facilities Program and National Research Program Funds.

    Science.gov (United States)

    2012-02-07

    ... GRANTS.GOV, (2) confirmation of successful validation by GRANTS.GOV and (3) confirmation of successful... be in TIP or STIP before the grant can be awarded. b. Describe applicant's experience with regional...: Solicitation of Project Proposals for Veterans Transportation and Community Living Initiative II...

  15. Plant programmed cell death, ethylene and flower senescence

    NARCIS (Netherlands)

    Woltering, E.J.; Jong, de A.; Hoeberichts, F.A.; Iakimova, E.T.; Kapchina, V.

    2005-01-01

    Programmed cell death (PCD) applies to cell death that is part of the normal life of multicellular organisms. PCD is found throughout the animal and plant kingdoms; it is an active process in which a cell suicide pathway is activated resulting in controlled disassembly of the cell. Most cases of PCD

  16. Programmed Cell Death and Postharvest Deterioration of Horticultural Produce

    NARCIS (Netherlands)

    Woltering, E.J.; Iakimova, E.T.

    2010-01-01

    Programmed cell death (PCD) is a process where cells or tissues are broken down in an orderly and predictable manner, whereby nutrients are re-used by other cells, tissues or plant parts. The process of (petal) senescence shows many similarities to autophagic PCD in animal cells including a massive

  17. Design of E-City Bus Tracking System

    Directory of Open Access Journals (Sweden)

    Shekhar Shinde

    2014-04-01

    Full Text Available E-city bus tracking system will serve as a viable notification system that will effectively assist passengers in making the decision of whether to wait for the bus or not. This system is a standalone system designed to display the real-time location(s of the buses with the use of GSM module technology. The system will consist of an IR transmitter module installed on the buses, receiver boards installed on the bus stops and GSM receiver connected with PC monitoring the whole arrangement. It will also have passenger information system software installed at the bus stops and which will provide user the relevant information regarding all the bus numbers going for his source to destination along with the route details. It will also transmit its bus numbers and route names, with the help of LED transmitter, continuously as soon as the bus comes within the range of the receiver at the bus stop.

  18. The Bus Station Spacing Optimization Based on Game Theory

    Directory of Open Access Journals (Sweden)

    Changjiang Zheng

    2015-01-01

    Full Text Available With the development of city, the problem of traffic is becoming more and more serious. Developing public transportation has become the key to solving this problem in all countries. Based on the existing public transit network, how to improve the bus operation efficiency, and reduce the residents transit trip cost has become a simple and effective way to develop the public transportation. Bus stop spacing is an important factor affecting passengers’ travel time. How to set up bus stop spacing has become the key to reducing passengers’ travel time. According to comprehensive traffic survey, theoretical analysis, and summary of urban public transport characteristics, this paper analyzes the impact of bus stop spacing on passenger in-bus time cost and out-bus time cost and establishes in-bus time and out-bus time model. Finally, the paper gets the balance best station spacing by introducing the game theory.

  19. Delay-Insensitive Synchronization on a Message-Passing Architecture with an Open Collector Bus

    NARCIS (Netherlands)

    Bekker, H.; Dijkstra, E.J.

    1996-01-01

    The performance of some algorithms, running on a message passing computer; is limited by the high latency of global communications. To increase the performance, a simple open collector bus, operated by delay insensitive programs running on each processor can be used. We illustrate this by an example

  20. Secure Bus-Ticketing System using NFC

    Directory of Open Access Journals (Sweden)

    Monalisa Lopes

    2015-04-01

    Full Text Available For making the day to day life more convenient for the passengers travelling in bus some technologies can be used like Near Field Communication (NFC, Radio Frequency Identification (RFID. The proposed system is based on ticketing and identification of passengers in public transport. The system suggest a user friendly automated ticketing system which will automatically deduct the passengers fare according to the distance travelled as well as detect the passengers detail information. The system also helps to calculate the total revenue of a single bus in a day. Another important aspect is reusability, which helps use ticket multiple times as it is rechargeable.

  1. NOC AND BUS ARCHITECTURE: A COMPARISON

    Directory of Open Access Journals (Sweden)

    RAJEEV KAMAL

    2012-04-01

    Full Text Available Network-on-chip designs promise to offer considerable advantages over the traditional bus-based architecture. As continuing scaling of Moore’s law enables ever greater transistor densities, design complexity, power limitations and application convergence networks have started to replace busses in much smaller systems and the enhancement of NoC. This paper summarizes the advantages of the NoC and the limitations of traditional bus based architecture. In this paper we discuss a detailed comparison of area, power, scalability andperformance of traditional busses in comparison with NoC.

  2. An Efficient Segmental Bus-Invert Coding Method for Instruction Memory Data Bus Switching Reduction

    Directory of Open Access Journals (Sweden)

    Gu Ji

    2009-01-01

    Full Text Available Abstract This paper presents a bus coding methodology for the instruction memory data bus switching reduction. Compared to the existing state-of-the-art multiway partial bus-invert (MPBI coding which relies on data bit correlation, our approach is very effective in reducing the switching activity of the instruction data buses, since little bit correlation can be observed in the instruction data. Our experiments demonstrate that the proposed encoding can reduce up to 42% of switching activity, with an average of 30% reduction, while MPBI achieves just 17.6% reduction in switching activity.

  3. Proton exchange membrane fuel cell system diagnosis based on the signed directed graph method

    Science.gov (United States)

    Hua, Jianfeng; Lu, Languang; Ouyang, Minggao; Li, Jianqiu; Xu, Liangfei

    The fuel-cell powered bus is becoming the favored choice for electric vehicles because of its extended driving range, zero emissions, and high energy conversion efficiency when compared with battery-operated electric vehicles. In China, a demonstration program for the fuel cell bus fleet operated at the Beijing Olympics in 2008 and the Shanghai Expo in 2010. It is necessary to develop comprehensive proton exchange membrane fuel cell (PEMFC) diagnostic tools to increase the reliability of these systems. It is especially critical for fuel-cell city buses serving large numbers of passengers using public transportation. This paper presents a diagnostic analysis and implementation study based on the signed directed graph (SDG) method for the fuel-cell system. This diagnostic system was successfully implemented in the fuel-cell bus fleet at the Shanghai Expo in 2010.

  4. Air quality on bus routes in Umea, Sweden

    Energy Technology Data Exchange (ETDEWEB)

    Sandberg, H.; Forsberg, B. [Dept. of Environmental Health and Dept. of Public Health and Clinical Medicine, Umea University SE, Umea (Sweden)

    2000-07-01

    Bus traffic in some local streets with up to 650 buses per day has resulted in complaints about air pollution and suggestions from residents that the bus routes should be changed to other streets. We have studied nitrogen dioxide and benzene concentrations at five exposed sites and at two representative control sites without bus traffic, and found no general differences in air quality. However, the site and temperature adjusted concentrations fell significantly during a strike among bus drivers. (authors)

  5. Framework for Bus Rapid Transit Development and Deployment Planning

    OpenAIRE

    Miller, Mark A.; Yin, Yafeng; Balvanyos, Tunde; Ceder, Avishai

    2004-01-01

    This report presents the results of its investigation into deployment planning for bus rapid transit systems. In this study, we conducted a macro-scale examination of bus rapid transit systems from technical, operational, institutional, and planning perspectives. We then developed the theoretical foundation for a deployment planning framework for bus rapid transit systems that specifically takes into account the unique features of bus rapid transit that differ from other transit alternatives....

  6. 2015 Annual Progress Report: DOE Hydrogen and Fuel Cells Program

    Energy Technology Data Exchange (ETDEWEB)

    None

    2015-12-23

    The 2015 Annual Progress Report summarizes fiscal year 2015 activities and accomplishments by projects funded by the DOE Hydrogen and Fuel Cells Program. It covers the program areas of hydrogen production; hydrogen delivery; hydrogen storage; fuel cells; manufacturing R&D; technology validation; safety, codes and standards; systems analysis; and market transformation.

  7. Bus Stops, This shapefile contains existing bus stops for Charlotte Area Transit System, Published in 2006, Charlotte Area Transit System.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Bus Stops dataset, was produced all or in part from Field Survey/GPS information as of 2006. It is described as 'This shapefile contains existing bus stops for...

  8. Peptic ulcer among urban bus drivers in Denmark

    DEFF Research Database (Denmark)

    Netterstrøm, Bo; Juel, K

    1990-01-01

    As part of a survey on the work environment of bus drivers, 2045 (83%) of 2465 male bus drivers in the three major cities in Denmark in 1978 answered a postal questionnaire on health and working conditions. In order to evaluate the relative occurrence of peptic ulcer among the bus drivers, a follow...

  9. An appraisal of QR code use to deliver bus arrival time information at bus stops in Southampton

    OpenAIRE

    Gammer, Nick

    2011-01-01

    The provision of at-stop bus arrival time information has numerous potential benefits to bus users. With real-time passenger information well established in the UK the challenge is relaying accurate bus arrival times to passengers in a cost effective manner. Display screens are costly to install and maintain, rendering placement at all bus stops economically undesirable. QR codes represent an inexpensive alternative to delivering this information, usually at zero marginal cost to users. Q...

  10. Internalization of NK cells into tumor cells requires ezrin and leads to programmed cell-in-cell death

    Institute of Scientific and Technical Information of China (English)

    Shan Wang; Zhen Guo; Peng Xia; Tingting Liu; Jufang Wang; Shan Li; Lihua Sun; Jianxin Lu; Qian Wen; Mingqian Zhou; Li Ma; Xia Ding; Xiaoning Wang; Xuebiao Yao

    2009-01-01

    Cytotoxic lymphocytes are key players in the orchestration of immune response and elimination of defective cells. We have previously reported that natural killer (NK) cells enter target tumor cells, leading to either target cell death or self-destruction within tumor cells. However, it has remained elusive as to the fate of NK cells after internaliza-tion and whether the heterotypic cell-in-cell process is different from that of the homotypic cell-in-cell event recently named entosis. Here, we show that NK cells undergo a cell-in-cell process with the ultimate fate of apoptosis within tumor cells and reveal that the internalization process requires the actin cytoskeletal regulator, ezrin. To visualize how NK cells enter into tumor cells, we carried out real-time dual color imaging analyses of NK cell internalization into tumor cells. Surprisingly, most NK cells commit to programmed cell death after their entry into tumor cells, which is distinctively different from entosis observed in the homotypic cell-in-cell process. The apoptotic cell death of the internalized NK cells was evident by activation of caspase 3 and DNA fragmentation. Furthermore, NK cell death after internalization is attenuated by the caspase inhibitor, Z-VAD-FMK, confirming apoptosis as the mode of NK cell death within tumor cells. To determine protein factors essential for the entry of NK cells into tumor cells, we car-ried out siRNA-based knockdown analysis and discovered a critical role of ezrin in NK cell internalization. Impor-tantly, PKA-mediated phosphorylation of ezrin promotes the NK cell internalization process. Our findings suggest a novel regulatory mechanism by which ezrin governs NK cell internalization into tumor cells.

  11. 1990 fuel cell seminar: Program and abstracts

    Energy Technology Data Exchange (ETDEWEB)

    1990-12-31

    This volume contains author prepared short resumes of the presentations at the 1990 Fuel Cell Seminar held November 25-28, 1990 in Phoenix, Arizona. Contained herein are 134 short descriptions organized into topic areas entitled An Environmental Overview, Transportation Applications, Technology Advancements for Molten Carbonate Fuel Cells, Technology Advancements for Solid Fuel Cells, Component Technologies and Systems Analysis, Stationary Power Applications, Marine and Space Applications, Technology Advancements for Acid Type Fuel Cells, and Technology Advancement for Solid Oxide Fuel Cells.

  12. Inrush-Current Limiter And Bus Isolator

    Science.gov (United States)

    Dolland, Carlisle R.

    1994-01-01

    Electronic circuit protects electrical power bus and source of power against excessive current demands. Circuit intended for use with power-consuming electronic system drawing pulsed currents and including capacitor bank as low-impedance secondary source from which pulsed currents drawn.

  13. Repeater For A Digital-Communication Bus

    Science.gov (United States)

    Torres-Guzman, Esteban; Olson, Stephen; Heaps, Tim

    1993-01-01

    Digital repeater circuit designed to extend range of communication on MIL-STD-1553 bus beyond original maximum allowable length of 300 ft. Circuit provides two-way communication, one way at time, and conforms to specifications of MIL-STD-1553. Crosstalk and instability eliminated.

  14. Bus 54 -- Where are you? A school bus intelligent information system

    Energy Technology Data Exchange (ETDEWEB)

    Truett, L.F.; Moore, S.; Tonn, B. [Oak Ridge National Lab., TN (United States); Conley, T. [GTE Wireless, Nashville, TN (United States)

    1998-07-01

    Although major accidents involving school buses are rare (only about 0.3% of all fatal crashes since 1986 are classified as school-bus-related), even minor accidents and breakdowns cause a great deal of parental anxiety. The objective of this research is to design an efficient, cost-effective, accurate, and secure system that will track individual school buses and communicate appropriate information to the school system`s central administration unit, to the school transportation administrator, and to parents of children on the bus. The greatest benefit of the proposed information system is that parents and officials can always know the location and condition (these conditions would vary depending on the needs of a particular school system) of the school buses. In case of an accident or mechanical problem, when emergency crews are needed, they can be dispatched almost immediately with a good understanding of the problem and the exact location of the bus. In addition to being able to track the bus while the child is on board, parents will be able to determine the location of their child`s bus prior to its arrival in the morning in order to prevent the child from needing to wait outside in inclement weather. The information available to parents can also be expanded to include maps of limited routes (e.g., snow routes). Basically, the Bus 54 concept consists of a bus component and a central data processing unit. Each bus will be outfitted with a global positioning satellite (GPS) device, a wireless communication device, and wireless data communication service. The central data processing unit will receive and process information from the buses and provide information access to parents and officials via an Internet link.

  15. Fuel Cell Seminar, 1992: Program and abstracts

    Energy Technology Data Exchange (ETDEWEB)

    1992-12-31

    This year`s theme, ``Fuel Cells: Realizing the Potential,`` focuses on progress being made toward commercial manufacture and use of fuel cell products. Fuel cell power plants are competing for market share in some applications and demonstrations of market entry power plants are proceeding for additional applications. Development activity on fuel cells for transportation is also increasing; fuel cell products have potential in energy and transportation industries, with very favorable environmental impacts. This Seminar has the purpose of fostering communication by providing a forum for the international community interested in development, application, and business opportunities related fuel cells. Over 190 technical papers are included, the majority being processed for the data base.

  16. Advanced eGovernment Information Service Bus (eGov-Bus

    Directory of Open Access Journals (Sweden)

    2007-01-01

    Full Text Available The eGov-Bus project provides citizens and businesses with improved access to virtual public services, which are based on existing national eGovernment Web services and which support cross-border life events. Requirements and specific rules of these life events are considered, and personalization of user preferences is supported. eGov-Bus is based on adaptable process management technologies, allowing for virtual services which are dynamically combined from existing national eGovernment services. In this way, a comprehensive workflow process is set up, allowing for service-level agreements, an audit trail and explanation of the process to the end user. The eGov-Bus process engine operates on top of a virtual repository, providing a high-level semantic view of information retrieved from heterogeneous information sources, such as eGovernment Web services. Further, eGov-Bus relies on a security framework to ensure all high-level security requirements are met. The eGov-Bus architecture is business oriented, it focuses on Service Oriented Architecture (SOA concepts, asynchronously combining Web services and providing a Service Bus.

  17. Regenerative polymeric bus architecture for board-level optical interconnects.

    Science.gov (United States)

    Bamiedakis, N; Hashim, A; Penty, R V; White, I H

    2012-05-21

    A scalable multi-channel optical regenerative bus architecture based on the use of polymer waveguides is presented for the first time. The architecture offers high-speed interconnection between electrical cards allowing regenerative bus extension with multiple segments and therefore connection of an arbitrary number of cards onto the bus. In a proof-of-principle demonstration, a 4-channel 3-card polymeric bus module is designed and fabricated on standard FR4 substrates. Low insertion losses (≤ -15 dB) and low crosstalk values (bus modules using a prototype 3R regenerator.

  18. Heat Transfer in the LHC Main Superconducting Bus Bars

    CERN Document Server

    Granieri, P P; Richter, D

    2011-01-01

    CERN is performing a systematic analysis of the interconnecting bus bars of the Large Hadron Collider (LHC) main magnets. Their thermal, electrical, mechanical and hydraulic performances are addressed. In the frame of these studies, the heat transfer between the main superconducting (SC) bus bars and the surrounding He bath is investigated. It represents a key parameter in the comprehension of the bus bars stability and quench propagation mechanisms, thus crucial for the analysis of the 2008 incident which was triggered by a defective bus bars joint. This paper reports on the experimental tests and relative analysis aiming at describing the thermal behavior of the LHC main bus bars.

  19. 2015 Annual Progress Report: DOE Hydrogen and Fuel Cells Program

    Energy Technology Data Exchange (ETDEWEB)

    Popovich, Neil

    2015-12-01

    In the past year, the DOE Hydrogen Program (the Program) made substantial progress toward its goals and objectives. The Program has conducted comprehensive and focused efforts to enable the widespread commercialization of hydrogen and fuel cell technologies in diverse sectors of the economy. With emphasis on applications that will effectively strengthen our nation's energy security and improve our stewardship of the environment, the Program engages in research, development, and demonstration of critical improvements in the technologies. Highlights of the Program's accomplishments can be found in the sub-program chapters of this report.

  20. 2012 Annual Progress Report: DOE Hydrogen and Fuel Cells Program

    Energy Technology Data Exchange (ETDEWEB)

    2012-12-01

    In the past year, the DOE Hydrogen Program (the Program) made substantial progress toward its goals and objectives. The Program has conducted comprehensive and focused efforts to enable the widespread commercialization of hydrogen and fuel cell technologies in diverse sectors of the economy. With emphasis on applications that will effectively strengthen our nation's energy security and improve our stewardship of the environment, the Program engages in research, development, and demonstration of critical improvements in the technologies. Highlights of the Program's accomplishments can be found in the sub-program chapters of this report.

  1. Plant programmed cell death and the point of no return

    NARCIS (Netherlands)

    Doorn, van W.G.

    2005-01-01

    The point of no return during programmed cell death (PCD) is defined as the step beyond which the cell is irreversibly committed to die. Some plant cells can be saved before this point by inducing the formation of functional chloroplasts. A visibly senescent tissue will then become green again and l

  2. Energy efficiency of different bus subsystems in Belgrade public transport

    Directory of Open Access Journals (Sweden)

    Mišanović Slobodan M.

    2015-01-01

    Full Text Available Research in this paper comprised experimental determination of energy efficiency of different bus subsystems (diesel bus, trolleybus and fully electric bus on chosen public transport route in Belgrade. Experimental measuring of energy efficiency of each bus type has been done based on the analysis of parameters of vehicle driving cycles between stops. Results of this analysis were basis for development of theoretical simulation model of energy efficiency. The model was latter compared with the results of simulation done by "Solaris bus & Coach" company for the chosen electric bus route. Based on demonstrated simulation, characteristics of electric bus batteries were defined, the method and dynamic of their recharge was suggested, as well as choice for other aggregates for drive system and technical characteristics for the electric buses were suggested.

  3. A Feeder-Bus Dispatch Planning Model for Emergency Evacuation in Urban Rail Transit Corridors

    Science.gov (United States)

    Wang, Yun; Yan, Xuedong; Zhou, Yu; Zhang, Wenyi

    2016-01-01

    The mobility of modern metropolises strongly relies on urban rail transit (URT) systems, and such a heavy dependence causes that even minor service interruptions would make the URT systems unsustainable. This study aims at optimally dispatching the ground feeder-bus to coordinate with the urban rails’ operation for eliminating the effect of unexpected service interruptions in URT corridors. A feeder-bus dispatch planning model was proposed for the collaborative optimization of URT and feeder-bus cooperation under emergency situations and minimizing the total evacuation cost of the feeder-buses. To solve the model, a concept of dummy feeder-bus system is proposed to transform the non-linear model into traditional linear programming (ILP) model, i.e., traditional transportation problem. The case study of Line #2 of Nanjing URT in China was adopted to illustrate the model application and sensitivity analyses of the key variables. The modeling results show that as the evacuation time window increases, the total evacuation cost as well as the number of dispatched feeder-buses decrease, and the dispatched feeder-buses need operate for more times along the feeder-bus line. The number of dispatched feeder-buses does not show an obvious change with the increase of parking spot capacity and time window, indicating that simply increasing the parking spot capacity would cause huge waste for the emergent bus utilization. When the unbalanced evacuation demand exists between stations, the more feeder-buses are needed. The method of this study will contribute to improving transportation emergency management and resource allocation for URT systems. PMID:27676179

  4. SPI总线接口扩展与应用%Extension and Application of SPI Bus Interface

    Institute of Scientific and Technical Information of China (English)

    郑毛祥

    2012-01-01

    In many kinds of the MCU, there are not SPI serial bus interface, thus limiting its use with SPI bus interface device. This paper introduces the SPI serial bus characteristics and timing, By using the MCU I/O port, through the program control method, simulating SPI serial bus interface, so that it can work with SPI bus interface device transfers data between, and in a serial E2PROM application as an example, introduces the simulation of SPI serial bus the use of the interface method.%在众多型号的单片机中,有许多不带SPI串行总线接口,从而限制了其对SPI总线接口器件的使用.本文介绍了SPI串行总线的特征和时序,对无SPI总线接口的单片机采用其I/O端口,通过程序控制的方法,模拟SPI串行总线接口,使其能与SPI总线接口的器件之间进行数据传送,并以串行E2PROM应用为例,介绍了模拟SPI串行总线接口的使用方法.

  5. ENVIRONMENTAL TECHNOLOGY VERIFICATION (ETV) PROGRAM: FUEL CELLS

    Science.gov (United States)

    The U.S. Environmental Protection Agency (EPA) Environmental Technology Verification (ETV) Program evaluates the performance of innovative air, water, pollution prevention and monitoring technologies that have the potential to improve human health and the environment. This techno...

  6. Mitochondrial Dynamics Controls T Cell Fate through Metabolic Programming.

    Science.gov (United States)

    Buck, Michael D; O'Sullivan, David; Klein Geltink, Ramon I; Curtis, Jonathan D; Chang, Chih-Hao; Sanin, David E; Qiu, Jing; Kretz, Oliver; Braas, Daniel; van der Windt, Gerritje J W; Chen, Qiongyu; Huang, Stanley Ching-Cheng; O'Neill, Christina M; Edelson, Brian T; Pearce, Edward J; Sesaki, Hiromi; Huber, Tobias B; Rambold, Angelika S; Pearce, Erika L

    2016-06-30

    Activated effector T (TE) cells augment anabolic pathways of metabolism, such as aerobic glycolysis, while memory T (TM) cells engage catabolic pathways, like fatty acid oxidation (FAO). However, signals that drive these differences remain unclear. Mitochondria are metabolic organelles that actively transform their ultrastructure. Therefore, we questioned whether mitochondrial dynamics controls T cell metabolism. We show that TE cells have punctate mitochondria, while TM cells maintain fused networks. The fusion protein Opa1 is required for TM, but not TE cells after infection, and enforcing fusion in TE cells imposes TM cell characteristics and enhances antitumor function. Our data suggest that, by altering cristae morphology, fusion in TM cells configures electron transport chain (ETC) complex associations favoring oxidative phosphorylation (OXPHOS) and FAO, while fission in TE cells leads to cristae expansion, reducing ETC efficiency and promoting aerobic glycolysis. Thus, mitochondrial remodeling is a signaling mechanism that instructs T cell metabolic programming. PMID:27293185

  7. Immunohistochemistry of Programmed Cell Death in Archival Human Pathology Specimens

    OpenAIRE

    Takami Matsuyama; Yoshito Eizuru; Takuro Kanekura; Yoshifumi Kawano; Shuji Izumo; Xinshan Jia; Katsuyuki Aozasa; Taku Nagai; Jia Wang; Kazuhisa Hasui

    2012-01-01

    Immunohistochemistry (IHC) for detecting key signal molecules involved in programmed cell death (PCD) in archival human pathology specimens is fairly well established. Detection of cleaved caspase-3 in lymphocytes in rheumatoid arthritis (RA) and gastric surface foveolar glandular epithelia but not in synoviocytes in RA, gastric fundic glandular epithelia, or nasal NK/T-cell lymphoma (NKTCL) cells suggests anti-apoptotic mechanisms in cell differentiation and in oncogenesis such as the induct...

  8. CIF2Cell: Generating geometries for electronic structure programs

    Science.gov (United States)

    Björkman, Torbjörn

    2011-05-01

    The CIF2Cell program generates the geometrical setup for a number of electronic structure programs based on the crystallographic information in a Crystallographic Information Framework (CIF) file. The program will retrieve the space group number, Wyckoff positions and crystallographic parameters, make a sensible choice for Bravais lattice vectors (primitive or principal cell) and generate all atomic positions. Supercells can be generated and alloys are handled gracefully. The code currently has output interfaces to the electronic structure programs ABINIT, CASTEP, CPMD, Crystal, Elk, Exciting, EMTO, Fleur, RSPt, Siesta and VASP. Program summaryProgram title: CIF2Cell Catalogue identifier: AEIM_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/AEIM_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: GNU GPL version 3 No. of lines in distributed program, including test data, etc.: 12 691 No. of bytes in distributed program, including test data, etc.: 74 933 Distribution format: tar.gz Programming language: Python (versions 2.4-2.7) Computer: Any computer that can run Python (versions 2.4-2.7) Operating system: Any operating system that can run Python (versions 2.4-2.7) Classification: 7.3, 7.8, 8 External routines: PyCIFRW [1] Nature of problem: Generate the geometrical setup of a crystallographic cell for a variety of electronic structure programs from data contained in a CIF file. Solution method: The CIF file is parsed using routines contained in the library PyCIFRW [1], and crystallographic as well as bibliographic information is extracted. The program then generates the principal cell from symmetry information, crystal parameters, space group number and Wyckoff sites. Reduction to a primitive cell is then performed, and the resulting cell is output to suitably named files along with documentation of the information source generated from any bibliographic information contained in the CIF

  9. Hopping on the methadone bus.

    Science.gov (United States)

    Lippert, Steffen; Schumacher, Christoph

    2009-05-01

    This paper investigates the impact of a 'free drug program' on the market equilibrium of drugs. We introduce a screening model of the hard drug market in which dealers use payment and punishment options to screen between high and low risk users. We show that, if a free drug program selects sufficiently many high-risk drug users, the pure-strategy separating market equilibrium ceases to exist and a symmetric mixed-strategy equilibrium results, in which drug users derive a higher expected utility. This encourages new drug users to enter the market. The novelty of the paper is the transmission mechanism for this effect, which is via the influence on market price. PMID:19344971

  10. An Audiovisual Program in Cell Biology

    Science.gov (United States)

    Fedoroff, Sergey; Opel, William

    1978-01-01

    A subtopic of cell biology, the structure and function of cell membranes, has been developed as a series of seven self-instructional slide-tape units and tested in five medical schools. Organization of advisers, analysis and definition of objectives and content, and development and evaluation of scripts and storyboards are discussed. (Author/LBH)

  11. Genetic regulation of programmed cell death in Drosophila

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    Programmed cell death plays an important role in maintaining homeostasis during animal development, and has been conserved in animals as different as nematodes and humans. Recent studies of Drosophila have provided valuable information toward our understanding of genetic regulation of death. Different signals trigger the novel death regulators rpr, hid, and grim, that utilize the evolutionarily conserved iap and ark genes to modulate caspase function. Subsequent removal of dying cells also appears to be accomplished by conserved mechanisms. The similarity between Drosophila and human in cell death signaling pathways illustrate the promise of fruit flies as a model system to elucidate the mechanisms underlying regulation of programmed cell death.

  12. Programmed cell death and its role in inflammation

    Institute of Scientific and Technical Information of China (English)

    Yong Yang; Ge-Ning Jiang; Peng Zhang; Jie Fan

    2015-01-01

    Cell death plays an important role in the regulation of inflammation and may be the result of inflammation. The maintenance of tissue homeostasis necessitates both the recognition and removal of invading microbial pathogens as well as the clearance of dying cells. In the past few decades, emerging knowledge on cell death and inflammation has enriched our molecular understanding of the signaling pathways that mediate various programs of cell death and multiple types of inflammatory responses. This review provides an overview of the major types of cell death related to inflammation. Modification of cell death pathways is likely to be a logical therapeutic target for inflammatory diseases.

  13. Quantum algorithm for programmed cell death of Caenorhabditis elegans

    International Nuclear Information System (INIS)

    During the development of Caenorhabditis elegans, through cell divisions, a total of exactly 1090 cells are generated, 131 of which undergo programmed cell death (PCD) to result in an adult organism comprising 959 cells. Of those 131, exactly 113 undergo PCD during embryogenesis, subdivided across the cell lineages in the following fashion: 98 for AB lineage; 14 for MS lineage; and 1 for C lineage. Is there a law underlying these numbers, and if there is, what could it be? Here we wish to show that the count of the cells undergoing PCD complies with the cipher laws related to the algorithms of Shor and of Grover

  14. BUS 475 UOP Course Tutorial/ Tutorialrank

    OpenAIRE

    john

    2015-01-01

    For more course tutorials visit www.tutorialrank.com Tutorial Purchased: 6 Times, Rating: A+   BUS 475 Capstone Final Examination Part 1   1.    In the managerial function of __________, managers encourage and motivate workers to work toward organizational goals.   2.    eBay.com is a vast auction site that is similar to a competitive market in some ways but differs from it in others. Which of the following describes...

  15. Exposure Assessment of Diesel Bus Emissions

    Directory of Open Access Journals (Sweden)

    Werner Hofmann

    2006-12-01

    Full Text Available The goal of this study was to measure ultrafine particle concentrations with diameters less than 1 μm emitted by diesel buses and to assess resulting human exposure levels. The study was conducted at the Woolloongabba Busway station in Brisbane, Australia in the winter months of 2002 during which temperature inversions frequently occurred. Most buses that utilize the station are fuelled by diesel, the exhaust of which contains a significant quantity of particle matter. Passengers waiting at the station are exposed to these particles emitted from the buses. During the course of this study, passenger census was conducted, based on video surveillance, yielding person-by-person waiting time data. Furthermore, a bus census revealed accurate information about the total number of diesel versus Compressed Natural Gas (CNG powered buses. Background (outside of the bus station and platform measurements of ultrafine particulate number size distributions were made to determine ambient aerosol concentrations. Particle number exposure concentration ranges from 10 and 40 to 60% of bus related exhaust fumes. This changes dramatically when considering the particle mass exposure concentration, where most passengers are exposed to about 50 to 80% of exhaust fumes. The obtained data can be very significant for comparison with similar work of this type because it is shown in previous studies that exhaust emissions causes cancer in laboratory animals. It was assumed that significant differences between platform and background distributions were due to bus emissions which, combined with passenger waiting times, yielded an estimate of passenger exposure to ultrafine particles from diesel buses. From an exposure point of view, the Busway station analyzed resembles a street canyon. Although the detected exhaust particle concentration at the outbound platform is found to be in the picogram range, exposure increases with the time passengers spend on the platform

  16. 2014 Annual Progress Report: DOE Hydrogen and Fuel Cells Program

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2014-11-01

    The 2014 Annual Progress Report summarizes fiscal year 2014 activities and accomplishments by projects funded by the DOE Hydrogen Program. It covers the program areas of hydrogen production and delivery; hydrogen storage; fuel cells; manufacturing; technology validation; safety, codes and standards; market transformation; and systems analysis.

  17. 2011 Annual Progress Report: DOE Hydrogen and Fuel Cells Program

    Energy Technology Data Exchange (ETDEWEB)

    Satyapal, Sunita [Office of Energy Efficiency and Renewable Energy (EERE), Washington, DC (United States)

    2011-11-01

    The 2011 Annual Progress Report summarizes fiscal year 2011 activities and accomplishments by projects funded by the DOE Hydrogen Program. It covers the program areas of hydrogen production and delivery; hydrogen storage; fuel cells; manufacturing; technology validation; safety, codes and standards; education; market transformation; and systems analysis.

  18. 2013 Annual Progress Report: DOE Hydrogen and Fuel Cells Program

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2013-12-01

    The 2013 Annual Progress Report summarizes fiscal year 2013 activities and accomplishments by projects funded by the DOE Hydrogen Program. It covers the program areas of hydrogen production and delivery; hydrogen storage; fuel cells; manufacturing; technology validation; safety, codes and standards; market transformation; and systems analysis.

  19. Chemical- and pathogen-induced programmed cell death in plants

    NARCIS (Netherlands)

    Iakimova, E.T.; Atanassov, A.; Woltering, E.J.

    2005-01-01

    This review focuses on recent update in the understanding of programmed cell death regarding the differences and similarities between the diverse types of cell death in animal and plant systems and describes the morphological and some biochemical determinants. The role of PCD in plant development an

  20. 基于RS485的小型PLC ModBus总线通信与实现%Bus Communication and Achieve of the Small PLC ModBus Based on RS485

    Institute of Scientific and Technical Information of China (English)

    杨帆

    2012-01-01

    ModBus作为一种开放式通信协议,愈来愈多地被小型PLC厂家选用,并逐渐成为产品的标准配置之一。首先介绍了汇川H2U系列PLC的ModBus总线通信技术,然后给出了实现H2UPLC与MD320变频器ModBus总线通信的硬件连接、变频器参数设置以及PLC通信程序。实际应用表明该方案工程实现容易、性价比高。%ModBus is increasing to choose by small PLC manufacturers as an open communication protocol, and becoming to one of the standard configuration of the product. Firstly the paper introduces bus communication technology of inovance H2U series PLC ModBus, and then achieves hardware connection,inverters parameter settings and PLC communication program of the H2U PLC and MD320 inverter ModBus bus communication. Practical application shows that the program works easily and cost -effectivly.

  1. Evolution of a 100 Mpbps fiber optic serial data bus for aerospace applications

    Science.gov (United States)

    Uhlhorn, R. W.; Geeslin, A. E.; Otten, T. H.

    Future aircraft and spacecraft will incorporate high speed data buses connecting avionics subsystems immersed in an electromagnetically hostile environment. The benefits of using fiber optics as the data transfer medium of choice for such systems are well known. Anticipating the use of high speed fiber optic data buses in avionics systems of the future, a company-sponsored program was initiated to explore component-through-system aspects of the technology. This paper describes the evolutionary steps in the development of a 100 Mbps Serial Fiber Optic Data Bus for aerospace applications. Beginning with a discussion of several possible protocols and applications, the development of each major subsystem is discussed. A token passing protocol is used to maximize bus efficiency. Development hardware supporting a 32 terminal network including an LED transmitter, APD receiver and user interface equipment, as well as test results from evaluation of the bus receivers and transmitters in a bus signaling environment, are described. Testing methods are discussed and test results are presented.

  2. Implementation of Transaction Level AMBA Bus Models Using SystemC

    Institute of Scientific and Technical Information of China (English)

    He Zhen; Cao Yang; Zhang Jun-xin; Ma Qin-sheng

    2004-01-01

    This paper deals with how to implement AMBA bus transaction level modeling in SystemC. There are two main techniques used in the whole modeling process, which consist of starting the platform modeling at the transaction level and using the uniformed modeling language--System C. According to the concepts of interface, port and hierarchical channel introduced in SystemC 2.0, the system of master-channel (AMBA bus) slave is created as the architecture of the AMBA bus transaction level model, which can make it more extendable. The port and interface classes of the model that are prone to program are defined in accordance with the SoC hierarchical design methodology. In addition, method calls, not signal communication, are used between different modules in the model, so the higher-level abstraction is achieved and the simulation performance is improved. The AMBA bus transaction level model is analyzed and certified by simulation experiment, and proved to be completely compliant to the AMBA specification 2.0.

  3. Fuel cell energy service Enron`s commerical program

    Energy Technology Data Exchange (ETDEWEB)

    Jacobson, M.W.

    1996-04-01

    Enron, the premier provider of clean fuels worldwide, has launched a unique energy service based on fuel cell technology. The goal of this program is to bring the benefits of fuel cell power to the broad commercial marketplace. Enron`s Energy Service is currently based on a 200 kilowatt phosphoric acid power plant manufactured by ONSI Corporation. This plant is fueled by natural gas or propane, and exhibits superior performance. Enron offers a `no hassle` package that provides customers with immediate benefits with no upfront capital or technical risks. This paper describes Enron`s fuel cell commercial program.

  4. Programmed Cell Death During Female Gametophyte Development

    Energy Technology Data Exchange (ETDEWEB)

    Drews, Gary, N.

    2004-09-15

    Endosperm is a storage tissue in the angiosperm seed that is important both biologically and agriculturally. Endosperm is biologically important because it provides nutrients to the embryo during seed development and agriculturally important because it is a significant source of food, feed, and industrial raw materials. Approximately two-thirds of human calories are derived from endosperm, either directly or indirectly through animal feed. Furthermore, endosperm is used as a raw material for numerous industrial products including ethanol. A major event in endosperm development is the transition between the syncytial phase, during which the endosperm nuclei undergo many rounds of mitosis without cytokinesis, and the cellularized phase, during which cell walls form around the endosperm nuclei. Understanding how the syncytial-cellular transition is regulated is agriculturally important because it influences seed size, seed sink strength, and grain weight. However, the molecular processes controlling this transition are not understood. This project led to the identification of the AGL62 gene that regulates the syncytial-cellular transition during endosperm development. AGL62 is expressed during the syncytial phase and suppresses endosperm cellularization during this period. AGL62 most likely does so by suppressing the expression of genes required for cellularization. At the end of the syncytial phase, the FIS PcG complex suppresses AGL62 expression, which allows expression of the cellularization genes and triggers the initiation of the cellularized phase. Endosperm arises following fertilization of the central cell within the female gametophyte. This project also led to the identification of the AGL80 gene that is required for development of the central cell into the endosperm. Within the ovule and seed, AGL80 is expressed exclusively in the central cell and uncellularized endosperm. AGL80 is required for expression of several central cell-expressed genes, including

  5. Programmed cell death: a way of life for plants.

    OpenAIRE

    Greenberg, J T

    1996-01-01

    Cell death in higher plants has been widely observed in predictable patterns throughout development and in response to pathogenic infection. Genetic, biochemical, and morphological evidence suggests that these cell deaths occur as active processes and can be defined formally as examples of programmed cell death (PCD). Intriguingly, plants have at least two types of PCD, an observation that is also true of PCD in animals [Schwartz, L. M., Smith, W.W., Jones, M. E. E. & Osborne, B. A. (1993) Pr...

  6. Programming CD8+ T cells for effective immunotherapy

    OpenAIRE

    Hinrichs, Christian S.; Gattinoni, Luca; Restifo, Nicholas P

    2006-01-01

    The differentiation state of CD8+ T cells has emerged as a crucial determinant of their ability to respond to tumor and infection. Signals from T-cell receptors, co-stimulatory molecules and cytokine receptors direct the differentiation process. These signals ‘program’ sustained and heritable gene expression patterns that govern progressive differentiation and lineage commitment. The epigenetic mechanisms by which T cells are programmed are just beginning to be elucidated. Understanding the m...

  7. Results of 200 KW fuel cell evaluation programs

    Energy Technology Data Exchange (ETDEWEB)

    Torrey, J.M.; Merten, G.P. [SAIC, San Diego, CA (United States); Binder, M.J. [Army Construction Engineering Research Labs., Champaign, IL (United States)] [and others

    1996-12-31

    Science Applications International Corporation (SAIC) has installed six monitoring systems on ONSI Corporation 200 kW phosphoric acid fuel cells. Three of the systems were installed for the U.S. Army Construction Engineering Research Laboratories (USACERL) which is coordinating the Department of Defense (DoD) fuel cell Demonstration Program and three were installed under a contract with the New York State Energy Research and Development Authority (NYSERDA). Monitoring of the three NYSERDA sites has been completed. Monitoring systems for the DoD fuel cells were installed in August, 1996 and thus no operating data was available at the time of this writing, but will be presented at the Fuel Cell Seminar. This paper will present the monitoring configuration and research approach for each program. Additionally, summary performance data is presented for the completed NYSERDA program.

  8. Study of bus driving parameters on urban route

    OpenAIRE

    Fuad DASHDAMIROV

    2011-01-01

    The article deals with bus traffic time and speed on stage and route in the whole. The factors affecting bus driving parameters are divided into groups. The factors of significant impact are found in each group. The method of consideration of such factors impact on driving parameters in timetable making, is proposed. The extent of impact of selected factors on bus driving time and speed is studied.

  9. The SMART MIL-STD-1553 bus adapter hardware manual

    Science.gov (United States)

    Ton, T. T.

    1981-01-01

    The SMART Multiplexer Interface Adapter, (SMIA) a complete system interface for message structure of the MIL-STD-1553, is described. It provides buffering and storage for transmitted and received data and handles all the necessary handshaking to interface between parallel 8-bit data bus and a MIL-STD serial bit stream. The bus adapter is configured as either a bus controller of a remote terminal interface. It is coupled directly to the multiplex bus, or stub coupled through an additional isolation transformer located at the connection point. Fault isolation resistors provide short circuit protection.

  10. Examination of an Urban City Bus Operating Conditions and Emissions

    OpenAIRE

    Soylu, Seref (Coordinador); Bal, Ayda; Semercioglu, Hulya; Ay, Eyup Fatih

    2010-01-01

    It was observed that real world driving characteristics of the city bus don’t correlate well with that of the ETC, which is the certification cycle for the city bus engines. For this reason it is not realistic to expect emission levels lower than corresponding EURO standards from the city bus during real world driving. City bus NOx emissions in terms of grams per second are increasing with engine load and speed but the total NOx emissions for entire trip are the maximum at the locations whe...

  11. Multi-Gigabit Rate Radiation Hard Bus Project

    Data.gov (United States)

    National Aeronautics and Space Administration — High speed robust very low power radiation hardened bus interconnects are required to accelerate on-board computations, further improve reconfigurability and...

  12. Bus accident severity and passenger injury: evidence from Denmark

    DEFF Research Database (Denmark)

    Prato, Carlo Giacomo; Kaplan, Sigal

    2014-01-01

    light. Occurrence of injury to bus passengers is positively related to (i) the involvement of heavy vehicles, (ii) crossing intersections in yellow or red light, (iii) open areas, (iv) high speed limits, and (v) slippery road surface. Conclusions The findings of the current study provide a comprehensive...... examining occurrence of injury to bus passengers. Results Bus accident severity is positively related to (i) the involvement of vulnerable road users, (ii) high speed limits, (iii) night hours, (iv) elderly drivers of the third party involved, and (v) bus drivers and other drivers crossing in yellow or red...

  13. Status of the IEEE P896 Future Backplane Bus

    International Nuclear Information System (INIS)

    The IEEE P896 Future Backplane Bus project has been influenced by and has influenced FASTBUS and several other contemporary bus designs. This paper summarizes the current status of that project, which is directed toward the needs of modern 32-bit microprocessor systems with multiple processors. Some of the technology developed for P896 will be important for future non-ECL implementations of FASTBUS and other buses. In particular, new bus drivers and receivers should greatly improve the performance and reliability of backplane buses and cable buses. The current status of the P896 serial bus is also summarized

  14. [Selective "death programs" or pleiotropic"life programs"? Looking for programmed cell death in the light of evolution].

    Science.gov (United States)

    Ameisen, Jean-Claude

    2005-01-01

    "Nothing in biology makes sense except in the light of evolution", wrote Theodosius Dobzhansky, one of the founders of the Modern Synthesis that led to the unification of evolutionary theory and genetics in the midst of the 20th century. Programmed cell death is a genetically regulated process of cell suicide that is central to the development, homeostasis and integrity of multicellular organisms. Conversely, the dysregulation of mechanisms controlling cell suicide plays a role in the pathogenesis of a wide range of diseases. While great progress has been achieved in the unveiling of the molecular mechanisms of programmed cell death, a new, and somehow puzzling level of complexity has recently begun to emerge, suggesting i) that several different self destruction pathways may exist and operate in parallel in our cells, and ii) that molecular effectors of cell suicide might also perform other functions unrelated to cell death induction and crucial to cell survival, such as cell differentiation, metabolism, and the regulation of the cell cycle. These new findings, with important physiopathological and therapeutic implications, seem at odds with the paradigm of programmed cell death derived from the studies of Caenorhabditis elegans, which led to the concept of the existence of selective, bona fide death genes that emerged and became selected for their sole capacity to execute or repress cell death. In this review, I will argue that this new level of complexity might only make sense and be understood when considered in a broader evolutionary context than that of our phylogenetic divergence from C. elegans. A new view of the regulated cell death pathways emerges when one attempts to ask the question of when and how they may have become selected during a timeline of 4 billion years, at the level of ancestral single-celled organisms, including the bacteria. I will argue that there may be no such thing as a bona fide genetic cell death program. Rather, in the framework of

  15. The Energy Management Strategy for a Series-Parallel Hybrid Electric Bus Based on Stochastic Dynamic Programming%基于随机动态规划的混联式混合动力客车能量管理策略

    Institute of Scientific and Technical Information of China (English)

    林歆悠; 孙冬野; 尹燕莉; 郝允志

    2012-01-01

    Aiming at the effects of many factors such as uncertain driving environment and different driver's styles on the fuel economy of novel series-parallel hybrid electric bus ( SPHEB) in real world driving conditions, a Markov model for driver's required power is built based on statistical data of several city driving cycles, and an energy management strategy based on stochastic dynamic programming ( SDP) algorithm is proposed and the control rules for power distribution between engine and battery are obtained. Both the results of simulation on the forward model for novel SPHEB and hardware-in-the-loop test demonstrate that the proposed strategy enables the battery SOC to keep balance within its preset range and makes the engine operate in high efficiency region. In addition the fuel consumption per 100km of novel SPHEB reduces by 30. 17% and 11.29% respectively compared with original bus and that with rule-based strategy.%针对实际行驶工况中不确定的行驶环境和不同的驾驶员风格等因素对新型混联式混合动力客车燃油经济性的影响,在统计若干城市循环工况数据的基础上建立驾驶员需求功率的马尔科夫模型,提出了一种基于随机动态规划算法的能量管理策略,获得了发动机和电池之间的功率分配控制规则.对新型混联式混合动力客车模型的仿真和硬件在环实验结果表明,所提出的策略能使电池荷电状态在预定的区域内保持平衡,使发动机运行工作点处于高效区域内,且整车100km油耗比原型客车和采用规则控制策略时分别降低了30.17%和11.29%.

  16. Liquid Tin Anode Direct Coal Fuel Cell Final Program Report

    Energy Technology Data Exchange (ETDEWEB)

    Tao, Thomas

    2012-01-26

    This SBIR program will result in improved LTA cell technology which is the fundamental building block of the Direct Coal ECL concept. As described below, ECL can make enormous efficiency and cost contributions to utility scale coal power. This program will improve LTA cells for small scale power generation. As described in the Commercialization section, there are important intermediate military and commercial markets for LTA generators that will provide an important bridge to the coal power application. The specific technical information from this program relating to YSZ electrolyte durability will be broadly applicable SOFC developers working on coal based SOFC generally. This is an area about which very little is currently known and will be critical for successfully applying fuel cells to coal power generation.

  17. Oracle Service Bus 11g Development Cookbook

    CERN Document Server

    Schmutz, Guido; van Zoggel, Jan

    2012-01-01

    This cookbook is full of immediately useable recipes showing you how to develop service and message-oriented (integration) applications on the Oracle Service Bus. In addition to its cookbook style, which ensures the solutions are presented in a clear step-by-step manner, the explanations go into great detail, which makes it good learning material for everyone who has experience in OSB and wants to improve. Most of the recipes are designed in such a way that each recipe is presented as a separate, standalone entity and reading of prior recipes is not required. The finished solution of each reci

  18. Bus bar joints stability and protection

    CERN Document Server

    Verweij, A

    2009-01-01

    A defective bus connection between two dipole magnets was the primary cause of the incident in sector 34 on September 19th. I will show how this could have happened, i.e. how a highly resistive joint has caused a thermal runaway and burned (or opened) before the QPS threshold was reached. In the second part of the talk I will present the new detection limits for the QPS upgrade of the RB and RQ circuits, required to avoid similar thermal runaways in the future.

  19. Redesign of Transjakarta Bus Driver's Cabin

    Science.gov (United States)

    Mardi Safitri, Dian; Azmi, Nora; Singh, Gurbinder; Astuti, Pudji

    2016-02-01

    Ergonomic risk at work stations with type Seated Work Control was one of the problems faced by Transjakarta bus driver. Currently “Trisakti” type bus, one type of bus that is used by Transjakarta in corridor 9, serving route Pinang Ranti - Pluit, gained many complaints from drivers. From the results of Nordic Body Map questionnaires given to 30 drivers, it was known that drivers feel pain in the neck, arms, hips, and buttocks. Allegedly this was due to the seat position and the button/panel bus has a considerable distance range (1 meter) to be achieved by drivers. In addition, preliminary results of the questionnaire using Workstation Checklist identified their complaints about uncomfortable cushion, driver's seat backrest, and the exact position of the AC is above the driver head. To reduce the risk level of ergonomics, then did research to design the cabin by using a generic approach to designing products. The risk analysis driver posture before the design was done by using Rapid Upper Limb Assessment (RULA), Rapid Entire Body Assessment (REBA), and Quick Exposure Checklist (QEC), while the calculation of the moment the body is done by using software Mannequin Pro V10.2. Furthermore, the design of generic products was done through the stages: need metric-matrix, house of quality, anthropometric data collection, classification tree concept, concept screening, scoring concept, design and manufacture of products in the form of two-dimensional. While the design after design risk analysis driver posture was done by using RULA, REBA, and calculation of moments body as well as the design visualized using software 3DMax. From the results of analysis before the draft design improvements cabin RULA obtained scores of 6, REBA 9, and the result amounted to 57.38% QEC and moment forces on the back is 247.3 LbF.inch and on the right hip is 72.9 LbF.in. While the results of the proposed improvements cabin design RULA obtained scores of 3, REBA 4, and the moment of force on

  20. The US Army Foreign Comparative Test fuel cell program

    Science.gov (United States)

    Bostic, Elizabeth; Sifer, Nicholas; Bolton, Christopher; Ritter, Uli; Dubois, Terry

    The US Army RDECOM initiated a Foreign Comparative Test (FCT) Program to acquire lightweight, high-energy dense fuel cell systems from across the globe for evaluation as portable power sources in military applications. Five foreign companies, including NovArs, Smart Fuel Cell, Intelligent Energy, Ballard Power Systems, and Hydrogenics, Inc., were awarded competitive contracts under the RDECOM effort. This paper will report on the status of the program as well as the experimental results obtained from one of the units. The US Army has interests in evaluating and deploying a variety of fuel cell systems, where these systems show added value when compared to current power sources in use. For low-power applications, fuel cells utilizing high-energy dense fuels offer significant weight savings over current battery technologies. This helps reduce the load a solider must carry for longer missions. For high-power applications, the low operating signatures (acoustic and thermal) of fuel cell systems make them ideal power generators in stealth operations. Recent testing has been completed on the Smart Fuel Cell A25 system that was procured through the FCT program. The "A-25" is a direct methanol fuel cell hybrid and was evaluated as a potential candidate for soldier and sensor power applications.

  1. A design of voltage measurement system based on simulated IIC bus%基于模拟ⅡC总线的电压测量系统

    Institute of Scientific and Technical Information of China (English)

    徐伟; 刘建成

    2011-01-01

    根据ⅡC总线的时序,编程模拟了ⅡC总线.基于模拟的ⅡC总线,采用8位串行接口A/D转换器PCF8591设计了电压测量系统.给出了系统硬件电路和主程序流程图.系统因采用ⅡC总线式结构而具有硬件结构简单、扩展性强的突出优点,为ⅡC总线在其他采集系统中的应用提供了参考.%IIC bus is simulated by C51 program according to its time sequence. Based on this simulated IIC bus, a voltage measurement system is designed by the single chip microcomputer and 8-bit A/D and D/A converter PCF8591. The PCF8591 is a single-chip, single-supply low power 8-bit CMOS data acquisition device with four analog inputs, one analog output and a serial IIC bus interface. Three address pins A0, A1 and A2 are used for programming the hardware address, allowing the use of up to eight devices connected to the IIC bus without additional hardware. Address, control and data to and from the device are transferred serially via the two-line bidirectional IIC bus.The functions of the PCF8591 include analog input multiplexing, on-chip track and hold function, 8-bit analog-todigital conversion and an 8-bit digital-to-analog conversion. The maximum conversion rate is given by the maximum speed of the IIC bus. The circuit and main program flow chart are proposed in this paper. The system has simple structure and strong expandability owes to the IIC bus. It provides reference for the application of IIC bus in acquisition system.

  2. Control of T cell antigen reactivity via programmed TCR downregulation.

    Science.gov (United States)

    Gallegos, Alena M; Xiong, Huizhong; Leiner, Ingrid M; Sušac, Bože; Glickman, Michael S; Pamer, Eric G; van Heijst, Jeroen W J

    2016-04-01

    The T cell antigen receptor (TCR) is unique in that its affinity for ligand is unknown before encounter and can vary by orders of magnitude. How the immune system regulates individual T cells that display very different reactivity to antigen remains unclear. Here we found that activated CD4(+) T cells, at the peak of clonal expansion, persistently downregulated their TCR expression in proportion to the strength of the initial antigen recognition. This programmed response increased the threshold for cytokine production and recall proliferation in a clone-specific manner and ultimately excluded clones with the highest antigen reactivity. Thus, programmed downregulation of TCR expression represents a negative feedback mechanism for constraining T cell effector function with a suitable time delay to thereby allow pathogen control while avoiding excess inflammatory damage. PMID:26901151

  3. Current status of Westinghouse tubular solid oxide fuel cell program

    Energy Technology Data Exchange (ETDEWEB)

    Parker, W.G. [Westinghouse Science and Technology Center, Pittsburgh, PA (United States)

    1996-04-01

    In the last ten years the solid oxide fuel cell (SOFC) development program at Westinghouse has evolved from a focus on basic material science to the engineering of fully integrated electric power systems. Our endurance for this cell is 5 to 10 years. To date we have successfully operated at power for over six years. For power plants it is our goal to have operated before the end of this decade a MW class power plant. Progress toward these goals is described.

  4. Network Extender for MIL-STD-1553 Bus

    Science.gov (United States)

    Marcus, Julius; Hanson, T. David

    2003-01-01

    An extender system for MIL-STD-1553 buses transparently couples bus components at multiple developer sites. The bus network extender is a relatively inexpensive system that minimizes the time and cost of integration of avionic systems by providing a convenient mechanism for early testing without the need to transport the usual test equipment and personnel to an integration facility. This bus network extender can thus alleviate overloading of the test facility while enabling the detection of interface problems that can occur during the integration of avionic systems. With this bus extender in place, developers can correct and adjust their own hardware and software before products leave a development site. Currently resident at Johnson Space Center, the bus network extender is used to test the functionality of equipment that, although remotely located, is connected through a MILSTD- 1553 bus. Inasmuch as the standard bus protocol for avionic equipment is that of MIL-STD-1553, companies that supply MIL-STD-1553-compliant equipment to government or industry and that need long-distance communication support might benefit from this network bus extender

  5. A High Efficiency DC Bus Regulator / RPC for Spacecraft Applications

    Science.gov (United States)

    Birchenough, Arthur G.

    2004-02-01

    DC bus voltage regulation may be required in future high powered spacecraft due to the length of the busses or because they are not generated at precise voltage levels. In these cases the regulation range is often only a few percent increase or decrease, but conventional DC voltage regulators switch all the power passing through them, and this level of power switched determines the size and losses in the regulator. A recently developed concept uses a low power DC-DC converter in series with the bus to raise or lower the bus voltage over a small range. This partial power processing technique combines the small size and power losses of the low power converter with the ability to regulate, (over a small range) a high power bus. The Series Connected Buck Boost Regulator (SCBBR) described herein provides bus regulation with an efficiency of 98%. The circuit also provides bus switching and overcurrent limiting functions of a Remote Power Controller (RPC). This paper describes the circuit design and performance of a breadboard SCBBR configured as a bus voltage regulator providing +/- 40% voltage regulation range, bus switching, and overload limiting.

  6. Network Analysis of Urban Traffic with Big Bus Data

    CERN Document Server

    Zhao, Kai

    2016-01-01

    Urban traffic analysis is crucial for traffic forecasting systems, urban planning and, more recently, various mobile and network applications. In this paper, we analyse urban traffic with network and statistical methods. Our analysis is based on one big bus dataset containing 45 million bus arrival samples in Helsinki. We mainly address following questions: 1. How can we identify the areas that cause most of the traffic in the city? 2. Why there is a urban traffic? Is bus traffic a key cause of the urban traffic? 3. How can we improve the urban traffic systems? To answer these questions, first, the betweenness is used to identify the most import areas that cause most traffics. Second, we find that bus traffic is not an important cause of urban traffic using statistical methods. We differentiate the urban traffic and the bus traffic in a city. We use bus delay as an identification of the urban traffic, and the number of bus as an identification of the bus traffic. Third, we give our solutions on how to improve...

  7. Review of bus drivers' occupational stress and stress prevention

    NARCIS (Netherlands)

    Kompier, M.A.J.; Di Martino, V.

    1995-01-01

    Although heterogeneous in methodology and content, 32 studies from 13 countries on bus drivers' work and health are similar in their conclusions. Bus-driving–characterized by high demands, low control and low support – can be regarded as a classic example of high-strain occupation, with high risks o

  8. Research and Development of Hybrid Electric Vehicles CAN-Bus Data Monitor and Diagnostic System through OBD-II and Android-Based Smartphones

    OpenAIRE

    Yalian Yang; Baolin Chen; Lin Su; Datong Qin

    2013-01-01

    With the rapid development of the smartphone market, future cars seem to have more connections with intelligent cell phone and Internet. Intelligent transportation system (ITS) and telematics system have become research focus in recent years. There is an increasing demand for remote monitoring and diagnostic system as the further research of hybrid electric vehicle (HEV) goes on. In this paper, a remote controller area network bus (CAN-Bus) data monitor and diagnostic system for HEV is presen...

  9. Djungle power. A more remote AC bus

    Energy Technology Data Exchange (ETDEWEB)

    Boehnke, Heinz W. [Technosol, Jork (Germany)

    2010-07-01

    The Dzanga-Sangha Reserve in the Central African Republic is probably one of the world's most remote protected rainforest areas, much to the benefit of the rare species of lowland gorilla, forest elephant and local pygmy population Ba'Aka. The park is co-managed by the ''WWF-World Wide Fund for Nature'' with sponsoring from the German Regenwald-Stiftung. In 2008 wwf decided to switch from the old, failing generator supply to a solar hybrid mini-grid, along with stringent measures of energy conservation and management. After a careful energy audit Technosol designed an AC-bus system with a 22 kWp PV generator which should overcome the dependency on the old generators and their fuel demands. For 15 buildings, an entirely new distribution network was installed, state of the art energy saving devices introduced and an energy metering system deviced. The installation is operating since August 2009. In such remote locations, the reliability of the AC-bus over other generator-based solutions will be demonstrated and with the support of international organisations like the wwf the practical application of solar hybrid supply becomes a landmark of sustainable energy concepts. (orig.)

  10. Taking Physics and Now the Stars on the Road With the Magic Physics Bus

    Science.gov (United States)

    Bennum, David

    2009-05-01

    In February 2003 the ``Physics on the Road'' workshop, held at Colorado State University- Fort Collins, Colorado, brought together physics faculty who were experienced in designing and providing year --round mobile physics displays and those who were interested in initiating similar outreach programs. The impetus for the workshop was the upcoming ``World Year of Physics'', but the workshop had much broader impact for many of us who attended. The University of Nevada had a long history of demonstration shows for campus visitors from K-12 students/faculty but the cost of field trips began to limit this for many schools, especially for schools in poorer neighborhoods without large scale parental fundraising. The timing of the workshop was perfect for my developing program to utilize a donated ``electric bus'' as a traveling physics demo showcase. The program has grown to near our current limitations (70 mile range of the bus and time considerations), however we are expanding the ``scope'' of the project to include evening astronomy ``star parties'' as we enter the ``Year of Astronomy''. In addition to the bus transport of portable astronomy equipment to school sites we are adding, through donation, a 22 inch telescope in a domed observatory at a secondary campus location at the edge of Reno where large scale ``star parties'' can be conducted as outreach to K-12 and the community. The ``Physics on the Road'' bus reaches several thousand elementary and middle school students every year now and the potential for similar outreach with ``Stars on the Road'' has excited several of our faculty and physics students into increased participation in these endeavors to introduce our young people to science. It has become one of our most active ``recruitment'' plans and growing numbers of local students entering physics and other science majors is anecdotal evidence of success.

  11. An Overview of Staged-bus Operation in Cities

    Directory of Open Access Journals (Sweden)

    Mohammad Hesam Hafezi

    2014-02-01

    Full Text Available In developing countries, demand for passenger travel is higher, due to economic growth. Government policy encourages people to use public transportation instead of their private carsto reduce of traffic congestion and air pollution. In the city areas, bus networks are the major part of the public transportation system because they are easily accessible and cheaper compared to other types of public transportation. In this study revelation of details of bus operation included different agents is studied. Bus operations, during provision of their service, have interaction with three main agents: bus agent, passenger agent and traffic agent. Study of the influence of each agent in bus operation is presented in this study, using the macroscopic way.

  12. Research on the Coordinated Design of Bus and Taxi Station

    Directory of Open Access Journals (Sweden)

    Jiangfeng Xi

    2015-01-01

    Full Text Available Rises in the number of transit buses, bus routes, and overall traffic volume in China’s cities, coupled with interference from other transport modes, such as taxis loading and unloading passengers nearby, have led to increasing traffic delays at bus stops, which is considered one of the factors degrading service levels and traffic operations on urban roadways. This paper studies traffic characteristics at bus stops, investigates variations in delay from different types or designs of bus stops, and analyzes the impact of it on traffic capacity, the purpose of which is to propose a solution to predicting the feasibility of an integrated design of bus stops and taxi stands with the help of mathematical models and based on the objectives of optimal traffic operations and passenger transfer.

  13. Low back trouble among urban bus drivers in Denmark

    DEFF Research Database (Denmark)

    Netterstrøm, Bo; Juel, K

    1989-01-01

    The occurrence of low back trouble and possible connection with psychosocial conditions among urban bus drivers were studied using a questionnaire and subsequent registration of hospital discharges. 2,045 (83%) full-time male bus drivers in the three largest cities in Denmark answered a questionn......The occurrence of low back trouble and possible connection with psychosocial conditions among urban bus drivers were studied using a questionnaire and subsequent registration of hospital discharges. 2,045 (83%) full-time male bus drivers in the three largest cities in Denmark answered...... a questionnaire in 1978 regarding psychosocial factors and health. The prevalence of frequent low back pain was 57%. In a control group of 195 motormen the prevalence was 40%. Standardized Morbidity Ratio for bus drivers discharged from hospital during the period 1978-1984 with the diagnosis lumbar disc...

  14. 77 FR 6178 - FY 2012 Discretionary Funding Opportunities: Bus and Bus Facilities Programs (State of Good...

    Science.gov (United States)

    2012-02-07

    ... June 16, 2009, DOT Secretary Ray LaHood, U.S. Department of Housing and Urban Development (HUD... a new partnership to help American families in all communities--rural, suburban and urban--gain... development and land recycling--to increase community revitalization, improve the efficiency of public...

  15. 76 FR 44979 - Section 5309 Discretionary Bus and Bus Facilities Program

    Science.gov (United States)

    2011-07-27

    ..., Flexible, Efficient, Transportation Equity Act: A Legacy For Users (SAFETEA-LU), Public Law 109-59, August... (VA) will make mobility management training assistance and support available to Veteran's Affairs... mobility management techniques within the VA system; and, 4. Commit to use innovative or...

  16. 75 FR 74134 - State of Good Repair Bus and Bus Facilities Discretionary Program Funds

    Science.gov (United States)

    2010-11-30

    ... State of Good Repair Initiative Notice of Funding Availability on May 4, 2010. The SGR Initiative makes..., maintaining, improving, and expanding physical assets effectively throughout their life cycles. FOR FURTHER... the criteria detailed in the May 4, 2010 Notice of Funding Availability. The projects selected...

  17. Workshop on programming beta cell development, impairment and regeneration

    DEFF Research Database (Denmark)

    Heller, Scott; Nielsen, Jens Høiriis

    2012-01-01

    Helsingør, the city of Hamlet in Denmark, provided the site for the workshop "Programming Beta Cell Development, Impairment and Regeneration" on October 23-26th, 2011. The same location has held two EASD Islet study group meetings, while the previous three workshops were held in Helsinki, Finland...

  18. Concise review: programming human pluripotent stem cells into blood.

    Science.gov (United States)

    Easterbrook, Jennifer; Fidanza, Antonella; Forrester, Lesley M

    2016-06-01

    Blood disorders are treated with cell therapies including haematopoietic stem cell (HSC) transplantation as well as platelet and red blood cell transfusions. However the source of cells is entirely dependent on donors, procedures are susceptible to transfusion-transmitted infections and serious complications can arise in recipients due to immunological incompatibility. These problems could be alleviated if it was possible to produce haematopoietic cells in vitro from an autologous and renewable cell source. The production of haematopoietic cells in the laboratory from human induced pluripotent stem cells (iPSCs) may provide a route to realize this goal but it has proven challenging to generate long-term reconstituting HSCs. To date, the optimization of differentiation protocols has mostly relied on the manipulation of extrinsic signals to mimic the in vivo environment. We review studies that have taken an alternative approach to modulate intrinsic signals by enforced expression of transcription factors. Single and combinations of multiple transcription factors have been used in a variety of contexts to enhance the production of haematopoietic cells from human pluripotent stem cells. This programming approach, together with the recent advances in the production and use of synthetic transcription factors, holds great promise for the production of fully functional HSCs in the future. PMID:26996518

  19. Concise review: programming human pluripotent stem cells into blood.

    Science.gov (United States)

    Easterbrook, Jennifer; Fidanza, Antonella; Forrester, Lesley M

    2016-06-01

    Blood disorders are treated with cell therapies including haematopoietic stem cell (HSC) transplantation as well as platelet and red blood cell transfusions. However the source of cells is entirely dependent on donors, procedures are susceptible to transfusion-transmitted infections and serious complications can arise in recipients due to immunological incompatibility. These problems could be alleviated if it was possible to produce haematopoietic cells in vitro from an autologous and renewable cell source. The production of haematopoietic cells in the laboratory from human induced pluripotent stem cells (iPSCs) may provide a route to realize this goal but it has proven challenging to generate long-term reconstituting HSCs. To date, the optimization of differentiation protocols has mostly relied on the manipulation of extrinsic signals to mimic the in vivo environment. We review studies that have taken an alternative approach to modulate intrinsic signals by enforced expression of transcription factors. Single and combinations of multiple transcription factors have been used in a variety of contexts to enhance the production of haematopoietic cells from human pluripotent stem cells. This programming approach, together with the recent advances in the production and use of synthetic transcription factors, holds great promise for the production of fully functional HSCs in the future.

  20. The influence of gymnastics in motor coordination and reaction time in urban public bus drivers

    Directory of Open Access Journals (Sweden)

    Stela Paula Mezzomo

    2014-12-01

    Full Text Available This study investigated the influence of labour gymnastics (LG on bus drivers' basic skills such as reaction time and gross motor coordination. Sixty male bus drivers (37.06 ± 7.66 years old from two bus lines in the city of Santa Maria (RS took part of this study. The participants were split into two groups, experimental group (EG and control group (CG. Subjects that were part of the EG took part in a LG intervention program, 2-3 times a week, over a year. Gross motor coordination was assessed by BURPEE Protocol (Johnson & Nelson, 1979, whereas reaction time by software providing a visual stimulus. Data normality was checked through Shapiro-Wilk test, which pointed to normal distribution only for the variables simple reaction time (SRT and choice reaction time (CRT in the EG. Therefore the non-parametric Mann-Whitney U test was selected to compare differences between groups. A statistically significant difference for gross motor coordination was found (z= −2.525, p= 0.012, suggesting the effectiveness of LG to improve motor skills. As regards SRT and CRT, no significant difference was found, in spite of better outcomes having been recorded after the LG program.

  1. A Model for Bus Crew Scheduling Problem with Multiple Duty Types

    Directory of Open Access Journals (Sweden)

    Mingming Chen

    2012-01-01

    Full Text Available This paper presents an approach for solving the bus crew scheduling problem which considers early, day, and late duty modes with time shift and work intensity constraints. Furthermore, the constraint with the least crew number of a certain duty (e.g., day duty has also been considered. An optimization model is formulated as a 0-1 integer programming problem to improve the efficiency of crew scheduling at the minimum expense of total idle time of crew for a circle bus line. Correspondingly, a heuristic algorithm utilizing the tabu search algorithm has been proposed to solve the model. Finally, the proposed model and algorithm are successfully tested by a case study.

  2. The wheels on the bus go "buy buy buy": school bus advertising laws.

    Science.gov (United States)

    Pomeranz, Jennifer L

    2012-09-01

    School buses, a practical necessity for millions of children, are at the center of new efforts to raise revenue. School bus advertising laws bring public health and commercialization concerns to the school setting. In doing so, they potentially expose school districts to First Amendment lawsuits. I examined various school bus advertising bills and laws. I reviewed First Amendment "forum analysis" as applied in the transit and school settings to clarify how this legal test may affect school districts subject to such laws. I have made recommendations for school districts to enact appropriate policies to ensure that such advertising does not undermine public health and to enable the districts to maintain control over their property.

  3. Generation of cardiac pacemaker cells by programming and differentiation.

    Science.gov (United States)

    Husse, Britta; Franz, Wolfgang-Michael

    2016-07-01

    A number of diseases are caused by faulty function of the cardiac pacemaker and described as "sick sinus syndrome". The medical treatment of sick sinus syndrome with electrical pacemaker implants in the diseased heart includes risks. These problems may be overcome via "biological pacemaker" derived from different adult cardiac cells or pluripotent stem cells. The generation of cardiac pacemaker cells requires the understanding of the pacing automaticity. Two characteristic phenomena the "membrane-clock" and the "Ca(2+)-clock" are responsible for the modulation of the pacemaker activity. Processes in the "membrane-clock" generating the spontaneous pacemaker firing are based on the voltage-sensitive membrane ion channel activity starting with slow diastolic depolarization and discharging in the action potential. The influence of the intracellular Ca(2+) modulating the pacemaker activity is characterized by the "Ca(2+)-clock". The generation of pacemaker cells started with the reprogramming of adult cardiac cells by targeted induction of one pacemaker function like HCN1-4 overexpression and enclosed in an activation of single pacemaker specific transcription factors. Reprogramming of adult cardiac cells with the transcription factor Tbx18 created cardiac cells with characteristic features of cardiac pacemaker cells. Another key transcription factor is Tbx3 specifically expressed in the cardiac conduction system including the sinoatrial node and sufficient for the induction of the cardiac pacemaker gene program. For a successful cell therapeutic practice, the generated cells should have all regulating mechanisms of cardiac pacemaker cells. Otherwise, the generated pacemaker cells serve only as investigating model for the fundamental research or as drug testing model for new antiarrhythmics. This article is part of a Special Issue entitled: Cardiomyocyte Biology: Integration of Developmental and Environmental Cues in the Heart edited by Marcus Schaub and Hughes Abriel.

  4. Generation of cardiac pacemaker cells by programming and differentiation.

    Science.gov (United States)

    Husse, Britta; Franz, Wolfgang-Michael

    2016-07-01

    A number of diseases are caused by faulty function of the cardiac pacemaker and described as "sick sinus syndrome". The medical treatment of sick sinus syndrome with electrical pacemaker implants in the diseased heart includes risks. These problems may be overcome via "biological pacemaker" derived from different adult cardiac cells or pluripotent stem cells. The generation of cardiac pacemaker cells requires the understanding of the pacing automaticity. Two characteristic phenomena the "membrane-clock" and the "Ca(2+)-clock" are responsible for the modulation of the pacemaker activity. Processes in the "membrane-clock" generating the spontaneous pacemaker firing are based on the voltage-sensitive membrane ion channel activity starting with slow diastolic depolarization and discharging in the action potential. The influence of the intracellular Ca(2+) modulating the pacemaker activity is characterized by the "Ca(2+)-clock". The generation of pacemaker cells started with the reprogramming of adult cardiac cells by targeted induction of one pacemaker function like HCN1-4 overexpression and enclosed in an activation of single pacemaker specific transcription factors. Reprogramming of adult cardiac cells with the transcription factor Tbx18 created cardiac cells with characteristic features of cardiac pacemaker cells. Another key transcription factor is Tbx3 specifically expressed in the cardiac conduction system including the sinoatrial node and sufficient for the induction of the cardiac pacemaker gene program. For a successful cell therapeutic practice, the generated cells should have all regulating mechanisms of cardiac pacemaker cells. Otherwise, the generated pacemaker cells serve only as investigating model for the fundamental research or as drug testing model for new antiarrhythmics. This article is part of a Special Issue entitled: Cardiomyocyte Biology: Integration of Developmental and Environmental Cues in the Heart edited by Marcus Schaub and Hughes Abriel

  5. Immunohistochemistry of Programmed Cell Death in Archival Human Pathology Specimens

    Directory of Open Access Journals (Sweden)

    Takami Matsuyama

    2012-05-01

    Full Text Available Immunohistochemistry (IHC for detecting key signal molecules involved in programmed cell death (PCD in archival human pathology specimens is fairly well established. Detection of cleaved caspase-3 in lymphocytes in rheumatoid arthritis (RA and gastric surface foveolar glandular epithelia but not in synoviocytes in RA, gastric fundic glandular epithelia, or nasal NK/T-cell lymphoma (NKTCL cells suggests anti-apoptotic mechanisms in cell differentiation and in oncogenesis such as the induction of survivin. Enzymatically pretreated and ultra-super sensitive detection of beclin-1 in synoviocytes in RA and gastric fundic glandular epithelia suggests enhanced autophagy. The deposition of beclin-1 in fibrinoid necrosis in RA and expression of beclin-1 in detached gastric fundic glandular cells suggest that enhanced autophagy undergoes autophagic cell death (ACD. NKTCL exhibited enhanced autophagy through LC3 labeling and showed densely LC3 labeled cell-debris in regions of peculiar necrosis without deposition of beclin-1, indicating massive ACD in NKTCL and the alternative pathway enhancing autophagy following autophagic vesicle nucleation. Autophagy progression was monitored by labeling aggregated mitochondria and cathepsin D. The cell-debris in massive ACD in NKTCL were positive for 8-hydroxydeoxyguanosine, suggesting DNA oxidation occurred in ACD. Immunohistochemical autophagy and PCD analysis in archival human pathology specimens may offer new insights into autophagy in humans.

  6. Developmental cell death programs license cytotoxic cells to eliminate histocompatible partners.

    Science.gov (United States)

    Corey, Daniel M; Rosental, Benyamin; Kowarsky, Mark; Sinha, Rahul; Ishizuka, Katherine J; Palmeri, Karla J; Quake, Stephen R; Voskoboynik, Ayelet; Weissman, Irving L

    2016-06-01

    In a primitive chordate model of natural chimerism, one chimeric partner is often eliminated in a process of allogeneic resorption. Here, we identify the cellular framework underlying loss of tolerance to one partner within a natural Botryllus schlosseri chimera. We show that the principal cell type mediating chimeric partner elimination is a cytotoxic morula cell (MC). Proinflammatory, developmental cell death programs render MCs cytotoxic and, in collaboration with activated phagocytes, eliminate chimeric partners during the "takeover" phase of blastogenic development. Among these genes, the proinflammatory cytokine IL-17 enhances cytotoxicity in allorecognition assays. Cellular transfer of FACS-purified MCs from allogeneic donors into recipients shows that the resorption response can be adoptively acquired. Transfer of 1 × 10(5) allogeneic MCs eliminated 33 of 78 (42%) recipient primary buds and 20 of 76 (20.5%) adult parental adult organisms (zooids) by 14 d whereas transfer of allogeneic cell populations lacking MCs had only minimal effects on recipient colonies. Furthermore, reactivity of transferred cells coincided with the onset of developmental-regulated cell death programs and disproportionately affected developing tissues within a chimera. Among chimeric partner "losers," severe developmental defects were observed in asexually propagating tissues, reflecting a pathologic switch in gene expression in developmental programs. These studies provide evidence that elimination of one partner in a chimera is an immune cell-based rejection that operates within histocompatible pairs and that maximal allogeneic responses involve the coordination of both phagocytic programs and the "arming" of cytotoxic cells. PMID:27217570

  7. Swisstrolley 3 - An articulated trolley bus; SWISSTROLLEY 3. Gelenktrolleybus

    Energy Technology Data Exchange (ETDEWEB)

    Gisler, H.-J.

    2006-07-01

    This illustrated final report for the Swiss Federal Office of Energy (SFOE) takes a look at the Swisstrolley 3 low-floor, articulated trolley bus developed in Switzerland by the Hess AG company. Various features of the variants of the trolley bus, including single vehicle, single and double-articulated buses and bus trailers, are discussed. The reductions achieved in energy consumption, weight and noise are discussed. Typical values for power consumption are presented in graphical form. Economic viability and passenger-friendliness are examined, as are possibilities for further improvement.

  8. Statistical Analysis for the Driving Cycle of Beijing's Bus

    Institute of Scientific and Technical Information of China (English)

    王震坡; 孙逢春; 王军; 孙立清

    2004-01-01

    According to the test data of the driving model for Beijing's bus routes, 9 parameters and the actual values of Beijing bus are confirmed to evaluate the driving cycle, 2 ways of establishing driving cycle model are analyzed, the formula of calculating driving cycle is acquired, and the calculating driving cycle model and the statistical driving cycle model for the buses in Beijing urban areas are set up. This study provides scientific basis for selecting the bus type and confirming the design parameters and the running method in Beijing.

  9. Development in Conducting Bus of RE-Al Alloys

    Institute of Scientific and Technical Information of China (English)

    李德富; 胡捷; 章萍芝; 石瑛; 李彦利

    2001-01-01

    Four kinds of deformed aluminum alloys were tested. One kind of RE-A1-Mg-Si alloy, which possessed high conductivity and strength, was the first priority by contrast test, The large specification bus of conducting aluminum all oys was made by thermomechanical process during the industrial experiment. The properties of the bus are as follows:the tensile strength σb is 238 MPa, the conductivity (v.s. IACS) is 54.3%, and the current-carrying capacity is beyond 3.1kA during working process. This kind of RE-Al alloy bus has been applied to several electrical transmitting and transforming work.

  10. A new MV bus transfer scheme for nuclear power plants

    Directory of Open Access Journals (Sweden)

    Chang Choong-Koo

    2015-01-01

    Full Text Available Fast bus transfer method is the most popular and residual voltage transfer method that is used as a backup in medium voltage buses in general. The use of the advanced technology like open circuit voltage prediction and digital signal processing algorithms can improve the reliability of fast transfer scheme. However, according to the survey results of the recent operation records in nuclear power plants, there were many instances where the fast transfer scheme has failed. To assure bus transfer in any conditions and circumstances, uninterruptible bus transfer scheme utilizing the state of the art medium voltage UPS is discussed and elaborated.

  11. The Metabolic Syndrome and its Association with Over Time Driving in Iranian Professional Bus Drivers

    Directory of Open Access Journals (Sweden)

    Afshin Blouri

    2010-01-01

    Full Text Available The aim of the study was to determine the prevalence of metabolic syndrome (MeS in professional bus drivers, and its association with overtime working hours among those drivers in Urmia, Iran. In this cross sectional study the studies population was 626 professional bus drivers, aged 20-69 yr. The MeS (according to the National Cholesterol Education Program Adult Treatment Panel III, Waist circumference, Systolic blood pressure, Diastolic blood pressure, Fasting plasma glucose, Triglyceride, HDL-cholesterol, age, and working time per week. The overall prevalence of the metabolic syndrome was 32.4%. The prevalence of the MeS was higher than the general Iranian population. There was a statistically significant positive relationship between over time driving and MeS (P: 0.028. This represents an odds ratio of 1.46 (95%CI: 1.04 – 2.05. The metabolic syndrome is becoming a noteworthy health problem in bus drivers; therefore, early detection and appropriate intervention need to be established.

  12. Common Traffic Violations of Bus Drivers in Urban China: An Observational Study

    OpenAIRE

    Qiqi Wang; , Wei Zhang; Rendong Yang; Yuanxiu Huang; Lin Zhang; Peishan Ning; Xunjie Cheng; Schwebel, David C; Guoqing Hu; Hongyan Yao

    2015-01-01

    Objective To report common traffic violations in bus drivers and the factors that influence those violations in urban China. Methods We conducted an observational study to record three types of traffic violations among bus drivers in Changsha City, China: illegal stopping at bus stations, violating traffic light signals, and distracted driving. The behaviors of bus drivers on 32 routes (20% of bus routes in the city) were observed. A two-level Poisson regression examined factors that predicte...

  13. Rfid-Based Automatic Bus Ticketing: Features and Trends

    Science.gov (United States)

    Oudah, A.

    2016-02-01

    Recent advancements in various technologies have made remarkable developments in various fields for public welfare and public transport is one such area. In the near future public bus transport system with advanced technologies like Radio Frequency Identification Device (RFID), GSM, GPS, ZigBee and RF modules will gain spotlight due to their advantage of higher convenience and greater life standards as compared to the conventional bus systems. In this paper, a comprehensive review of all several proposed bus ticketing and bus information methods has been presented in detail. The study brings out improved solution in terms of cost, convenience, user satisfaction and future implementation. The choice of working modules and their efficient performance has been discussed along with the highlighted importance of the need of technology for welfare of common public and visually impaired.

  14. Constant of heat conduction and stabilization of bus bar conductor

    Science.gov (United States)

    López, G.

    Using the one-dimensional, time-independent conduction state, a constant of heat conduction is given bringing about the known stabilization theorem and a closed expression for the bus bar to be cryogenically stable in superconducting accelerators.

  15. Optimization Model for Headway of a Suburban Bus Route

    Directory of Open Access Journals (Sweden)

    Xiaohong Jiang

    2014-01-01

    Full Text Available Due to relatively low passenger demand, headways of suburban bus route are usually longer than those of urban bus route. Actually it is also difficult to balance the benefits between passengers and operators, subject to the service standards from the government. Hence the headway of a suburban bus route is usually determined on the empirical experience of transport planners. To cope with this problem, this paper proposes an optimization model for designing the headways of suburban bus routes by minimizing the operating and user costs. The user costs take into account both the waiting time cost and the crowding cost. The feasibility and validity of the proposed model are shown by applying it to the Route 206 in Jiangning district, Nanjing city of China. Weightages of passengers’ cost and operating cost are further discussed, considering different passenger flows. It is found that the headway and objective function are affected by the weightages largely.

  16. Optimal control system of the intermittent bus-only approach

    Institute of Scientific and Technical Information of China (English)

    Jie Jiang; Yulin Chang

    2014-01-01

    To guarantee bus priority with a minimum impact on car traffic at intersections, an optimal control system of the intermittent bus-only approach (IBA) was proposed. The problems of the existing system are first solved through optimization: the judgment time of the IBA system was advanced to allow a bus to jump car queues if the bus was detected to arrive at the intersection, and the instant that the IBA lane became available to cars was controlled dynamically to increase the capacity of the IBA lane. The total car delay in one cycle was then analyzed quantitatively when implementing the optimal control system. The results show that in comparison with the existing system of the IBA, the car delay is greatly reduced and the probability of a car stopping twice is low after optimizing the IBA system.

  17. Study on the Bus Real-time Dispatching Model

    Institute of Scientific and Technical Information of China (English)

    YingZou; JianguoLi; JianhuaHuang; ZhenminTang

    2004-01-01

    The real-time dispatching model on bus system is studied in this article. Realtime dispatching can resume the planned schedule quickly, and then to ensure the reliability of the public transport service and to well raise the service quality.

  18. Bus Passenger Recognition and Track of Video Sequence

    Directory of Open Access Journals (Sweden)

    Donghua Zhou

    2013-06-01

    Full Text Available Study on bus passenger recognition and track of video sequence is a research aiming at realizing making a statistics on passenger flow volume of bus, which not only helps traffic services center rationally schedule vehicles, but also can avoid overload. The system makes machine vision technology and digital image processing technique applied in customer counting of bus. The key questions in the study include effective collection of video image, effective extraction of moving object in sequence images, recognition of moving targets, trace and count of moving objects. The paper makes deep analysis on relevant technology from the perspective of the theory and practical application of the algorithm, and the study makes achievements. The theoretical algorithm for the study on bus passenger recognition and track of video sequence is distinctive. The practical experiments indicate that the system can satisfy the real-time requirements, and can accurately make statistics on the number of passengers, which has great application value.

  19. Examining the Optimal Fuel Type for Urban Bus Operations

    OpenAIRE

    CAULFIELD, BRIAN

    2010-01-01

    PUBLISHED Washington D.C. Public service fleets offer an attractive option for introducing renewable fuels and alternative technologies on a large scale, which allow for the reduction of both greenhouse gas emissions and exhaust air pollutants. This paper ex amines the use of biomethane (bio-CNG) and compressed natural gas (CNG) for part of the bus fleet in Dublin. Dublin is typical of many international urban centres with a large bus fleet; therefore the results...

  20. Compressed natural gas bus safety: a quantitative risk assessment.

    Science.gov (United States)

    Chamberlain, Samuel; Modarres, Mohammad

    2005-04-01

    This study assesses the fire safety risks associated with compressed natural gas (CNG) vehicle systems, comprising primarily a typical school bus and supporting fuel infrastructure. The study determines the sensitivity of the results to variations in component failure rates and consequences of fire events. The components and subsystems that contribute most to fire safety risk are determined. Finally, the results are compared to fire risks of the present generation of diesel-fueled school buses. Direct computation of the safety risks associated with diesel-powered vehicles is possible because these are mature technologies for which historical performance data are available. Because of limited experience, fatal accident data for CNG bus fleets are minimal. Therefore, this study uses the probabilistic risk assessment (PRA) approach to model and predict fire safety risk of CNG buses. Generic failure data, engineering judgments, and assumptions are used in this study. This study predicts the mean fire fatality risk for typical CNG buses as approximately 0.23 fatalities per 100-million miles for all people involved, including bus passengers. The study estimates mean values of 0.16 fatalities per 100-million miles for bus passengers only. Based on historical data, diesel school bus mean fire fatality risk is 0.091 and 0.0007 per 100-million miles for all people and bus passengers, respectively. One can therefore conclude that CNG buses are more prone to fire fatality risk by 2.5 times that of diesel buses, with the bus passengers being more at risk by over two orders of magnitude. The study estimates a mean fire risk frequency of 2.2 x 10(-5) fatalities/bus per year. The 5% and 95% uncertainty bounds are 9.1 x 10(-6) and 4.0 x 10(-5), respectively. The risk result was found to be affected most by failure rates of pressure relief valves, CNG cylinders, and fuel piping.

  1. Bus Implementation Using New Low Power PFSCL Tristate Buffers

    OpenAIRE

    Neeta Pandey; Bharat Choudhary; Kirti Gupta; Ankit Mittal

    2016-01-01

    This paper proposes new positive feedback source coupled logic (PFSCL) tristate buffers suited to bus applications. The proposed buffers use switch to attain high impedance state and modify the load or the current source section. An interesting consequence of this is overall reduction in the power consumption. The proposed tristate buffers consume half the power compared to the available switch based counterpart. The issues with available PFSCL tristate buffers based bus implementation are id...

  2. Ion channels involved in cell volume regulation: effects on migration, proliferation, and programmed cell death in non adherent EAT cells and adherent ELA cells.

    Science.gov (United States)

    Hoffmann, Else Kay

    2011-01-01

    This mini review outlines studies of cell volume regulation in two closely related mammalian cell lines: nonadherent Ehrlich ascites tumour cells (EATC) and adherent Ehrlich Lettre ascites (ELA) cells. Focus is on the regulatory volume decrease (RVD) that occurs after cell swelling, the volume regulatory ion channels involved, and the mechanisms (cellular signalling pathways) that regulate these channels. Finally, I shall also briefly review current investigations in these two cell lines that focuses on how changes in cell volume can regulate cell functions such as cell migration, proliferation, and programmed cell death.

  3. Antisense bcl-2 treatment increases programmed cell death in non-small cell lung cancer cell lines.

    Science.gov (United States)

    Koty, P P; Zhang, H; Levitt, M L

    1999-02-01

    Programmed cell death (PCD) is a genetically regulated pathway that is altered in many cancers. This process is, in part, regulated by the ratio of PCD inducers (Bax) or inhibitors (Bcl-2). An abnormally high ratio of Bcl-2 to Bax prevents PCD, thus contributing to resistance to chemotherapeutic agents, many of which are capable of inducing PCD. Non-small cell lung cancer (NSCLC) cells demonstrate resistance to these PCD-inducing agents. If Bcl-2 prevents NSCLC cells from entering the PCD pathway, then reducing the amount of endogenous Bcl-2 product may allow these cells to spontaneously enter the PCD pathway. Our purpose was to determine the effects of bcl-2 antisense treatment on the levels of programmed cell death in NSCLC cells. First, we determined whether bcl-2 and bax mRNA were expressed in three morphologically distinct NSCLC cell lines: NCI-H226 (squamous), NCI-H358 (adenocarcinoma), and NCI-H596 (adenosquamous). Cells were then exposed to synthetic antisense bcl-2 oligonucleotide treatment, after which programmed cell death was determined, as evidenced by DNA fragmentation. Bcl-2 protein expression was detected immunohistochemically. All three NSCLC cell lines expressed both bcl-2 and bax mRNA and had functional PCD pathways. Synthetic antisense bcl-2 oligonucleotide treatment resulted in decreased Bcl-2 levels, reduced cell proliferation, decreased cell viability, and increased levels of spontaneous PCD. This represents the first evidence that decreasing Bcl-2 in three morphologically distinct NSCLC cell lines allows the cells to spontaneously enter a PCD pathway. It also indicates the potential therapeutic use of antisense bcl-2 in the treatment of NSCLC. PMID:10217615

  4. Cyclosporin A inhibits programmed cell death and cytochrome c release induced by fusicoccin in sycamore cells.

    Science.gov (United States)

    Contran, N; Cerana, R; Crosti, P; Malerba, M

    2007-01-01

    Programmed cell death plays a vital role in normal plant development, response to environmental stresses, and defense against pathogen attack. Different types of programmed cell death occur in plants and the involvement of mitochondria is still under investigation. In sycamore (Acer pseudoplatanus L.) cultured cells, the phytotoxin fusicoccin induces cell death that shows apoptotic features, including chromatin condensation, DNA fragmentation, and release of cytochrome c from mitochondria. In this work, we show that cyclosporin A, an inhibitor of the permeability transition pore of animal mitochondria, inhibits the cell death, DNA fragmentation, and cytochrome c release induced by fusicoccin. In addition, we show that fusicoccin induces a change in the shape of mitochondria which is not prevented by cyclosporin A. These results suggest that the release of cytochrome c induced by fusicoccin occurs through a cyclosporin A-sensitive system that is similar to the permeability transition pore of animal mitochondria and they make it tempting to speculate that this release may be involved in the phytotoxin-induced programmed cell death of sycamore cells.

  5. Integration of a platform based in field bus (profibus), for the development of process control systems; Integracion de una plataforma basada en bus de campo PROFIBUS, para el desarrollo de sistemas de control de procesos

    Energy Technology Data Exchange (ETDEWEB)

    Islas Perez, Eduardo; Arroyo Figueroa, Gustavo; Villavicencio Ramirez, Alejandro [Instituto de Investigaciones Electricas, Cuernavaca (Mexico)

    1994-03-01

    The integration of a computer platform for the process sequential control system development and validation of some processes of thermoelectric generation, which are constituted by operations of the logic-sequential type. The platform is composed of a process simulator, a sequence tester, a logic programmable controller, and an operational computer. All these elements are interconnected through a field bus type PROFIBUS (Process Field Bus) (Standard DIN 19245). This platform has been used for the elaboration and evaluation of the operational sequence and control of demineralization, reverse osmosis, and condensate polishing water treatment plants, which are simulated in a personal computer. [Espanol] Se presenta la integracion de una plataforma de computo para el desarrollo y validacion de sistemas de control secuencial de algunos procesos de generacion termoelectrica, los cuales estan constituidos por operaciones de tipo logico-secuencial. La plataforma esta compuesta por un simulador del proceso, un probador de secuencias, un controlador logico programable y una computadora de operacion. Todos estos elementos estan interconectados a traves de un bus de campo tipo PROFIBUS (Process Field Bus), (Estandar DIN 19245). Esta plataforma se ha utilizado para elaborar y validar la programacion de las secuencias de operacion y control de plantas de tratamiento de agua por desmineralizacion, osmosis inversa y pulidores de condensados, las cuales se tienen simuladas en una computadora personal

  6. CROSS-FRONTIER PUBLIC TRANSPORT: Y BUS

    CERN Document Server

    CERN Housing Service

    2002-01-01

    'Y' buses cover the journey between Val Thoiry in France (shopping centre including'Migros' and other stores) and Blandonnet in Switzerland, where they stop outside the 'Jumbo' shop, now renamed 'Carrefour'. In France, the buses connect up Thoiry, Sergy and St. Genis, then cross the border to stop outside CERN, Meyrin, before continuing towards Geneva along the 'Route de Meyrin', stopping outside the 'La Tour' hospital, then at the terminus Blandonnet. The normal fare on French territory with a slight incursion into Switzerland for this purpose as far as CERN, Meyrin, is 1.20 Euros per single journey (ticket valid for one hour). The same amount is charged for any single journey in Switzerland. For example, the cost of a single journey between St. Genis and the 'La Tour' hospital would be 2.40 Euros. The season ticket ('Abonnement de Travail') opens the right to purchase a ticket valid over any period of seven days which entitles the holder to as many journeys as required between the bus stop nearest to the pl...

  7. Cellular Programming and Reprogramming: Sculpting Cell Fate for the Production of Dopamine Neurons for Cell Therapy

    Directory of Open Access Journals (Sweden)

    Julio C. Aguila

    2012-01-01

    success of clinical applications depends on our ability to steer pluripotent stem cells towards the right neuronal identity. In Parkinson disease, the loss of dopamine neurons is more pronounced in the ventrolateral population that projects to the sensorimotor striatum. Because synapses are highly specific, only neurons with this precise identity will contribute, upon transplantation, to the synaptic reconstruction of the dorsal striatum. Thus, understanding the developmental cell program of the mesostriatal dopamine neurons is critical for the identification of the extrinsic signals and cell-intrinsic factors that instruct and, ultimately, determine cell identity. Here, we review how extrinsic signals and transcription factors act together during development to shape midbrain cell fates. Further, we discuss how these same factors can be applied in vitro to induce, select, and reprogram cells to the mesostriatal dopamine fate.

  8. The Australian Hydrogen and Fuel Cells Education Program

    International Nuclear Information System (INIS)

    The next generation of engineers and scientists will face great technical, economic and political challenges to satisfy increasing demands for a secure, reliable and affordable global energy system that maintains and enhances current standards of living. The Australian Hydrogen and Fuel Cells Education Program aims to bolster the quality and relevance of primary and secondary school teaching in emerging areas of science, technology and environmental/sustainability studies using hydrogen, in its capacity as a versatile energy carrier, as the educational basis for teacher and student learning. Critical advances in specific areas of hydrogen production, distribution, storage and end-use technologies arise when students are engaged to develop and apply a broad range of disciplinary and interdisciplinary knowledge and practical skills. A comprehensive hydrogen and fuel cell technology teaching module will be developed to complement existing fuels and energy curricula across Australian schools. The pilot program will be delivered via the collaboration of nine trial schools, a broad range of technical and pedagogy experts and representatives of professional bodies and industry. The program features essential and extensive teacher consultation, a professional learning and development course, industry site visits and a dedicated research and evaluation study. This initiative aims to bolster teacher literacy and student participation in the design, construction and operation of various hydrogen and fuel cell devices and extended activities. Students will reflect on and formally present their learning experiences via several dedicated fora including an awards ceremony where outstanding performance of leading schools, teachers and student groups within the cluster will be acknowledged. (authors)

  9. The Australian Hydrogen and Fuel Cells Education Program

    Energy Technology Data Exchange (ETDEWEB)

    Luigi Bonadio [Senior Consultant Luigi Bonadio and Associates (Australia)

    2006-07-01

    The next generation of engineers and scientists will face great technical, economic and political challenges to satisfy increasing demands for a secure, reliable and affordable global energy system that maintains and enhances current standards of living. The Australian Hydrogen and Fuel Cells Education Program aims to bolster the quality and relevance of primary and secondary school teaching in emerging areas of science, technology and environmental/sustainability studies using hydrogen, in its capacity as a versatile energy carrier, as the educational basis for teacher and student learning. Critical advances in specific areas of hydrogen production, distribution, storage and end-use technologies arise when students are engaged to develop and apply a broad range of disciplinary and interdisciplinary knowledge and practical skills. A comprehensive hydrogen and fuel cell technology teaching module will be developed to complement existing fuels and energy curricula across Australian schools. The pilot program will be delivered via the collaboration of nine trial schools, a broad range of technical and pedagogy experts and representatives of professional bodies and industry. The program features essential and extensive teacher consultation, a professional learning and development course, industry site visits and a dedicated research and evaluation study. This initiative aims to bolster teacher literacy and student participation in the design, construction and operation of various hydrogen and fuel cell devices and extended activities. Students will reflect on and formally present their learning experiences via several dedicated fora including an awards ceremony where outstanding performance of leading schools, teachers and student groups within the cluster will be acknowledged. (authors)

  10. Catching up with solid tumor oncology: what is the evidence for a prognostic role of programmed cell death-ligand 1/programmed cell death-1 expression in B-cell lymphomas?

    Science.gov (United States)

    McClanahan, Fabienne; Sharp, Thomas G.; Gribben, John G.

    2016-01-01

    Therapeutic strategies targeting the programmed cell death-ligand 1/programmed cell death-1 pathway have shown significant responses and good tolerability in solid malignancies. Although preclinical studies suggest that inhibiting programmed cell death-ligand 1/programmed cell death-1 interactions might also be highly effective in hematological malignancies, remarkably few clinical trials have been published. Determining patients who will benefit most from programmed cell death-ligand 1/programmed cell death-1-directed immunotherapy and whether programmed cell death-ligand 1/programmed cell death-1 are adequate prognostic markers becomes an increasingly important clinical question, especially as aberrant programmed cell death-ligand 1/programmed cell death-1 expression are key mediators of impaired anti-tumor immune responses in a range of B-cell lymphomas. Herein, we systematically review the published literature on the expression and prognostic value of programmed cell death-ligand 1/programmed cell death-1 in these patients and identify considerable differences in expression patterns, distribution and numbers of programmed cell death-ligand 1+/programmed cell death-1+cells, both between and within lymphoma subtypes, which is reflected in conflicting findings regarding the prognostic value of programmed cell death-ligand 1+/programmed cell death-1+ cells. This can be partly explained by differences in methodologies (techniques, protocols, cutoff values) and definitions of positivity. Moreover, lymphomagenesis, disease progression, and prognosis appear to be determined not only by the presence, numbers and distribution of specific subtypes of T cells, but also by other cells and additional immune checkpoints. Collectively, our findings indicate that programmed cell death-ligand 1/programmed cell death-1 interactions play an essential role in B-cell lymphoma biology and are of clinical importance, but that the overall outcome is determined by additional components

  11. Programmed Cell Death Progresses Differentially in Epidermal and Mesophyll Cells of Lily Petals.

    Directory of Open Access Journals (Sweden)

    Hiroko Mochizuki-Kawai

    Full Text Available In the petals of some species of flowers, programmed cell death (PCD begins earlier in mesophyll cells than in epidermal cells. However, PCD progression in each cell type has not been characterized in detail. We separately constructed a time course of biochemical signs and expression patterns of PCD-associated genes in epidermal and mesophyll cells in Lilium cv. Yelloween petals. Before visible signs of senescence could be observed, we found signs of PCD, including DNA degradation and decreased protein content in mesophyll cells only. In these cells, the total proteinase activity increased on the day after anthesis. Within 3 days after anthesis, the protein content decreased by 61.8%, and 22.8% of mesophyll cells was lost. A second peak of proteinase activity was observed on day 6, and the number of mesophyll cells decreased again from days 4 to 7. These biochemical and morphological results suggest that PCD progressed in steps during flower life in the mesophyll cells. PCD began in epidermal cells on day 5, in temporal synchrony with the time course of visible senescence. In the mesophyll cells, the KDEL-tailed cysteine proteinase (LoCYP and S1/P1 nuclease (LoNUC genes were upregulated before petal wilting, earlier than in epidermal cells. In contrast, relative to that in the mesophyll cells, the expression of the SAG12 cysteine proteinase homolog (LoSAG12 drastically increased in epidermal cells in the final stage of senescence. These results suggest that multiple PCD-associated genes differentially contribute to the time lag of PCD progression between epidermal and mesophyll cells of lily petals.

  12. Programmed cell death of Ulmus pumila L. seeds during aging

    Institute of Scientific and Technical Information of China (English)

    Yulan ZHANG; Ming ZHANG; Fang LI; Xiaofeng WANG

    2008-01-01

    The programmed cell death (PCD) character-istics of Ulmus pumila L. seeds were investigated. The seeds were treated at a high temperature of 37℃ and 100% relative humidity for six days. DAPI (4'6-diami-dino-2-phenylindole) staining revealed that the aging treatment induced condensation and margination of chro-matin, as well as the formation of apoptotic bodies. DNA electrophoresis results of U. pumila seeds on an agarose gel showed a characteristic "ladder" pattern. Levels of electrolyte leakage of seed cells showed that membranes retained their integral form during almost the entire aging time. There was an immediate increase in the production rate of superoxide anion (O2-) and in the amount of hydrogen peroxide (H2O2), which remained at a μmol level. All of these common characteristics indicate that seed aging can be classified as PCD.

  13. Program Area of Interest: Fuel Transformer Solid Oxide Fuel Cell

    Energy Technology Data Exchange (ETDEWEB)

    Norman Bessette; Douglas S. Schmidt; Jolyon Rawson; Rhys Foster; Anthony Litka

    2006-02-01

    The following report documents the technical approach and conclusions made by Acumentrics Corporation during latest budget period toward the development of a low cost 10kW tubular SOFC power system. The present program, guided under direction from the National Energy Technology Laboratory of the US DOE, is a nine-year cost shared Cooperative Agreement totaling close to $74M funded both by the US DOE as well as Acumentrics Corporation and its partners. The latest budget period ran from July of 2005 through December 2005. Work focused on cell technology enhancements as well as BOP and power electronics improvements and overall system design. Significant progress was made in increasing cell power enhancements as well as decreasing material cost in a drive to meet the SECA cost targets. The following report documents these accomplishments in detail as well as the layout plans for further progress in next budget period.

  14. Using microfluidics to study programmed cell death: A new approach

    DEFF Research Database (Denmark)

    Mark, Christina; Zor, Kinga; Heiskanen, Arto;

    This project focuses on applying microfluidic tissue culture for electrochemical or optical measurements during programmed cell death (PCD) in barley aleurone layer to increase understanding of the underlying mechanisms of PCD in plants. Microfluidic tissue culture enables in vitro experiments......, we are optimising an intracellular whole-cell redox activity assay3 that detects changes in redox activity in barley aleurone layer during PCD. The assay uses a double mediator-system to electrochemically measure redox activity via changes in the NADP:NADPH ratio. Initial experiments assay show...... that the redox activity changes depending on phytohormone activation or inactivation of aleurone layer metabolism and subsequent PCD. This is similar to H2O2 concentration changes observed recently by Ishibashi et al4. We have also successfully detected PCD induced by phytohormones in barley aleurone layer using...

  15. DoD Climate Change Fuel Cell Program

    Energy Technology Data Exchange (ETDEWEB)

    Ken Olsen

    2006-09-15

    's main circuit while the hot water flows from the fuel cell to the college through a closed loop equipped with internal heat exchangers mounted on a custom skid in the boiler room. Fresh make-up water for the fuel cell's reverse osmosis equipment is piped separately from the boiler room out to the fuel cell. The fuel cell operates in parallel with the local electric utility's distribution system that serves the general area. The interconnection design relies on the grid protection components that come as standard equipment in the FCE unit design. Ultimately, the only substantive approval for the installation was for the parallel interconnection with the grid, provided by Jersey Central Power & Light. The utility had a well-defined set of interconnection requirements and procedures for units under 5 MW, and the approval process went smoothly and caused little delays. The primary liaison with PPL and the college was the utility's account representative. PPL and the college report that JCP&L was quite supportive of the project. The 60 percent reimbursement of installed costs was made through the New Jersey Clean Energy Fund, which is in turn funded through utility contributions. The Department of Energy provided an additional $250,000 grant under the Department of Defense fuel cell buy down program. PPL started testing the fuel cell on October 31, 2003. Final acceptance of the fuel cell was completed on December 21, 2003. Following several months of start-up activities, a high availability factor and few operating difficulties have marked operations during the first year.

  16. Advanced Intelligent System Application to Load Forecasting and Control for Hybrid Electric Bus

    Science.gov (United States)

    Momoh, James; Chattopadhyay, Deb; Elfayoumy, Mahmoud

    1996-01-01

    The primary motivation for this research emanates from providing a decision support system to the electric bus operators in the municipal and urban localities which will guide the operators to maintain an optimal compromise among the noise level, pollution level, fuel usage etc. This study is backed up by our previous studies on study of battery characteristics, permanent magnet DC motor studies and electric traction motor size studies completed in the first year. The operator of the Hybrid Electric Car must determine optimal power management schedule to meet a given load demand for different weather and road conditions. The decision support system for the bus operator comprises three sub-tasks viz. forecast of the electrical load for the route to be traversed divided into specified time periods (few minutes); deriving an optimal 'plan' or 'preschedule' based on the load forecast for the entire time-horizon (i.e., for all time periods) ahead of time; and finally employing corrective control action to monitor and modify the optimal plan in real-time. A fully connected artificial neural network (ANN) model is developed for forecasting the kW requirement for hybrid electric bus based on inputs like climatic conditions, passenger load, road inclination, etc. The ANN model is trained using back-propagation algorithm employing improved optimization techniques like projected Lagrangian technique. The pre-scheduler is based on a Goal-Programming (GP) optimization model with noise, pollution and fuel usage as the three objectives. GP has the capability of analyzing the trade-off among the conflicting objectives and arriving at the optimal activity levels, e.g., throttle settings. The corrective control action or the third sub-task is formulated as an optimal control model with inputs from the real-time data base as well as the GP model to minimize the error (or deviation) from the optimal plan. These three activities linked with the ANN forecaster proving the output to the

  17. Application of CAN Bus Technology on Zhongtong Bus%CAN总线技术在中通客车上的应用

    Institute of Scientific and Technical Information of China (English)

    赵佳

    2012-01-01

    The application status of CAN bus technology on Zhongtong bus is introduced, the methods of bus data collection and analysis on Zhongtong traditional and new energy bus are discussed and the development direction of CAN bus technology is prospected.%介绍CAN总线技术在中通客车上的应用状况,探讨中通传统客车及新能源客车的总线数据采集和分析方法。

  18. Modulation of Programmed Cell Death in a Model System of Xylogenic Zinnia (Zinnia Elegans) Cell Culture

    NARCIS (Netherlands)

    Yakimova, E.T.; Woltering, E.J.

    2009-01-01

    Programmed cell death is an integral part of the latest stage of differentiation of the tracheary elements of plant xylem vascular system. In this study, by applying a pharmacological approach with specific peptide inhibitors, we have elucidated the involvement of plant caspase-like proteases in cel

  19. Photodynamic therapy-induced programmed cell death in carcinoma cell lines

    Science.gov (United States)

    He, Xiao-Yan; Sikes, Robert A.; Thomsen, Sharon L.; Chung, L.; Jacques, Steven L.

    1993-06-01

    The mode of cell death following photodynamic therapy (PDT) was investigated from the perspective of programmed cell death (apoptosis). Human prostate carcinoma cells (PC3), human non-small cell lung carcinoma (H322a), and rat mammary carcinoma (MTF7) were treated by PDT following sensitization with dihematoporphyrin ether (DHE). The response of these carcinoma cell lines to PDT was variable. An examination of extracted cellular DNA by gel electrophoresis showed the characteristic DNA ladder pattern indicative of internucleosomal cleavage of DNA during apoptosis. MTF7 and PC3 responded to PDT by inducing apoptosis while H322a had no apoptotic response. The magnitude of the response and the PDT dosage required to induce the effect were different in PC3 and MTF7. MTF7 cells responded with rapid apoptosis at the dose of light and drug that yielded 50% cell death (LD50). In contrast, PC3 showed only marginal apoptosis at the LD50 but had a marked response at the LD85. Furthermore, the onset of apoptosis followed slower kinetics in PC3 (2 hr - 4 hr) than in MTF7 (cells were killed by PDT but failed to exhibit any apoptotic response. This study indicates that apoptosis may occur during PDT induced cell death, but this pathway is not universal for all cancer cell lines.

  20. 324 and 325 Building hot cell cleanout program: Decontamination of C-Cell

    International Nuclear Information System (INIS)

    During FY 1989 the decontamination of C-Cell of Hanford's 324 Building was completed as part of the 324 and 325 Building Hot Cell Cleanout Program sponsored by the DOE Nuclear Energy's Surplus Facilities Management Program. The decontamination effort was completed using a series of remote and contact decontamination techniques. Initial radiation readings in C-Cell averaged 50 rad/hr and were reduced remotely to less than 200 mrad/hr using an alkaline foam cleaner followed by a 5000-psi water flush. Contact decontamination was then permissible using ultra high-pressure water, at 36,000 psi, further reducing the average radiation level in the cell to less than 86 mrem/hr. The approach used in decontaminating C-Cell resulted in a savings in radiation exposure of 87% and a cost savings of 39% compared to a hands-on procedure used in A-Cell, 324 Building in 1987. The radiation dose and the costs to achieve a 244-fold reduction in radiation contamination were 1.65 mrem per ft2 and $96 per ft2 of cell surface area. 14 figs., 4 tabs

  1. 324 and 325 Building hot cell cleanout program: Decontamination of C-Cell

    Energy Technology Data Exchange (ETDEWEB)

    Katayama, Y.B.; Holton, L.K. Jr.

    1989-10-01

    During FY 1989 the decontamination of C-Cell of Hanford's 324 Building was completed as part of the 324 and 325 Building Hot Cell Cleanout Program sponsored by the DOE Nuclear Energy's Surplus Facilities Management Program. The decontamination effort was completed using a series of remote and contact decontamination techniques. Initial radiation readings in C-Cell averaged 50 rad/hr and were reduced remotely to less than 200 mrad/hr using an alkaline foam cleaner followed by a 5000-psi water flush. Contact decontamination was then permissible using ultra high-pressure water, at 36,000 psi, further reducing the average radiation level in the cell to less than 86 mrem/hr. The approach used in decontaminating C-Cell resulted in a savings in radiation exposure of 87% and a cost savings of 39% compared to a hands-on procedure used in A-Cell, 324 Building in 1987. The radiation dose and the costs to achieve a 244-fold reduction in radiation contamination were 1.65 mrem per ft{sup 2} and $96 per ft{sup 2} of cell surface area. 14 figs., 4 tabs.

  2. Car Delay Model near Bus Stops with Mixed Traffic Flow

    Directory of Open Access Journals (Sweden)

    Yang Xiaobao

    2013-01-01

    Full Text Available This paper proposes a model for estimating car delays at bus stops under mixed traffic using probability theory and queuing theory. The roadway is divided to serve motorized and nonmotorized traffic streams. Bus stops are located on the nonmotorized lanes. When buses dwell at the stop, they block the bicycles. Thus, two conflict points between car stream and other traffic stream are identified. The first conflict point occurs as bicycles merge to the motorized lane to avoid waiting behind the stopping buses. The second occurs as buses merge back to the motorized lane. The average car delay is estimated as the sum of the average delay at these two conflict points and the delay resulting from following the slower bicycles that merged into the motorized lane. Data are collected to calibrate and validate the developed model from one site in Beijing. The sensitivity of car delay to various operation conditions is examined. The results show that both bus stream and bicycle stream have significant effects on car delay. At bus volumes above 200 vehicles per hour, the curbside stop design is not appropriate because of the long car delays. It can be replaced by the bus bay design.

  3. Capacity Region of a New Bus Communication Model

    Directory of Open Access Journals (Sweden)

    Zhuojun Zhuang

    2013-02-01

    Full Text Available In this paper, we study a new bus communication model, where two transmitters wish to send their corresponding private messages and a common message to a destination, while they also wish to send the common message to another receiver connected to the same wire. From an information-theoretical point of view, we first study a general case of this new model (with discrete memoryless channels. The capacity region composed of all achievable (R0,R1,R2 triples is determined for this general model, where R1 and R2 are the transmission rates of the private messages and R0 is the transmission rate of the common message. Then, the result is further explained via the Gaussian example. Finally, we give the capacity region for the new bus communication model with additive Gaussian noises and attenuation factors. This new bus communication model captures various communication scenarios, such as the bus systems in vehicles, and the bus type of communication channel in power line communication (PLC networks.

  4. A role for programmed cell death in the microbial loop.

    Directory of Open Access Journals (Sweden)

    Mónica V Orellana

    Full Text Available The microbial loop is the conventional model by which nutrients and minerals are recycled in aquatic eco-systems. Biochemical pathways in different organisms become metabolically inter-connected such that nutrients are utilized, processed, released and re-utilized by others. The result is that unrelated individuals end up impacting each others' fitness directly through their metabolic activities. This study focused on the impact of programmed cell death (PCD on a population's growth as well as its role in the exchange of carbon between two naturally co-occurring halophilic organisms. Flow cytometric, biochemical, ¹⁴C radioisotope tracing assays, and global transcriptomic analyses show that organic algal photosynthate released by Dunalliela salina cells undergoing PCD complements the nutritional needs of other non-PCD D. salina cells. This occurs in vitro in a carbon limited environment and enhances the growth of the population. In addition, a co-occurring heterotroph Halobacterium salinarum re-mineralizes the carbon providing elemental nutrients for the mixoheterotrophic chlorophyte. The significance of this is uncertain and the archaeon can also subsist entirely on the lysate of apoptotic algae. PCD is now well established in unicellular organisms; however its ecological relevance has been difficult to decipher. In this study we found that PCD in D. salina causes the release of organic nutrients such as glycerol, which can be used by others in the population as well as a co-occurring halophilic archaeon. H. salinarum also re-mineralizes the dissolved material promoting algal growth. PCD in D. salina was the mechanism for the flow of dissolved photosynthate between unrelated organisms. Ironically, programmed death plays a central role in an organism's own population growth and in the exchange of nutrients in the microbial loop.

  5. Temporal rhythm of petal programmed cell death in Ipomoea purpurea.

    Science.gov (United States)

    Gui, M-Y; Ni, X-L; Wang, H-B; Liu, W-Z

    2016-09-01

    Flowers are the main sexual reproductive organs in plants. The shapes, colours and scents of corolla of plant flowers are involved in attracting insect pollinators and increasing reproductive success. The process of corolla senescence was investigated in Ipomoea purpurea (Convolvulaceae) in this study. In the research methods of plant anatomy, cytology, cell chemistry and molecular biology were used. The results showed that at the flowering stage cells already began to show distortion, chromatin condensation, mitochondrial membrane degradation and tonoplast dissolution and rupture. At this stage genomic DNA underwent massive but gradual random degradation. However, judging from the shape and structure, aging characteristics did not appear until the early flower senescence stage. The senescence process was slow, and it was completed at the late stage of flower senescence with a withering corolla. We may safely arrive at the conclusion that corolla senescence of I. purpurea was mediated by programmed cell death (PCD) that occurred at the flowering stage. The corolla senescence exhibited an obvious temporal rhythm, which demonstrated a high degree of coordination with pollination and fertilization. PMID:27259176

  6. Bachelor of Science-Engineering Technology Program and Fuel Cell Education Program Concentration

    Energy Technology Data Exchange (ETDEWEB)

    Block, David L. [Florida Solar Energy Center, Cocoa, FL (United States); Sleiti, Ahmad [Univ. of North Carolina, Charlotte, NC (United States)

    2011-09-19

    The Hydrogen and Fuel Cell Technology education project has addressed DOE goals by supplying readily available, objective, technical, and accurate information that is available to students, industry and the public. In addition, the program has supplied educated trainers and training opportunities for the next generation workforce needed for research, development, and demonstration activities in government, industry, and academia. The project has successfully developed courses and associated laboratories, taught the new courses and labs and integrated the HFCT option into the accredited engineering technology and mechanical engineering programs at the University of North Carolina at Charlotte (UNCC). The project has also established ongoing collaborations with the UNCC energy related centers of the Energy Production & Infrastructure Center (EPIC), the NC Motorsports and Automotive Research Center (NCMARC) and the Infrastructure, Design, Environment and Sustainability Center (IDEAS). The results of the project activities are presented as two major areas – (1) course and laboratory development, offerings and delivery, and (2) program recruitment, promotions and collaborations. Over the project period, the primary activity has been the development and offering of 11 HFCT courses and accompanying laboratories. This process has taken three years with the courses first being developed and then offered each year over the timeframe.

  7. Contagion processes on urban bus networks in Indian cities

    CERN Document Server

    Chatterjee, Atanu; Jagannathan, Krishna

    2015-01-01

    Bus transportation is considered as one of the most convenient and cheapest modes of public transportation in Indian cities. Due to their cost-effectiveness and wide reachability, they help a significant portion of the human population in cities to reach their destinations every day. Although from a transportation point of view they have numerous advantages over other modes of public transportation, they also pose a serious threat of contagious diseases spreading throughout the city. The presence of numerous local spatial constraints makes the process and extent of epidemic spreading extremely difficult to predict. Also, majority of the studies have focused on the contagion processes on scale-free network topologies whereas, spatially-constrained real-world networks such as, bus networks exhibit a wide-spectrum of network topology. Therefore, we aim in this study to understand this complex dynamical process of epidemic outbreak and information diffusion on the bus networks for six different Indian cities usin...

  8. Optimal Locations of Bus Stops Connecting Subways near Urban Intersections

    Directory of Open Access Journals (Sweden)

    Yuan Cui

    2015-01-01

    Full Text Available Unsuitable locations of bus stops which provide feeder transportation connecting subways near urban intersections usually lead to the low efficiency of public transport and level of passenger service. A multiobjective optimization model to distribute such stop locations is proposed to attain the shortest total walk distance of passengers and minimum delay time of cars through intersections and travel time of buses. The Pareto frontier and optimal solutions for the proposed model are given by the distance-based and enumerative methods. The Xizhimen bus stop is selected to implement case studies for verifying the validity of the proposed model. The analysis of sensitivity on possible solutions is also carried out in the case studies. The results show that the proposed model is capable of optimizing the locations of bus stops connecting subways near intersections and helpful to improve the level of passengers service and operational efficiency of public transportation.

  9. High Performance BDR for the PCU of AlphaBus

    Science.gov (United States)

    Subrier, Laurent; Besdel, Patrick; Daubresse, Thierry; Trehet, Eric

    2008-09-01

    Very high-power satellites for Telecom missions require 100V bus. Some Telecom payloads may be used in TDMA mode with a power modulation up to 30% of the Payload power. Full performance of the PCU is required in this case even in eclipse mode. It is clear that this requirement is very demanding especially for the BDR design.100V bus system leads making this requirement more difficult as Bus and Battery short-circuit protections have to operate under a voltage of 100V. This paper describes first the overall BDR design with a special focus on the innovative battery short-circuit protection that is not achieved by a "classical" series SSPC on the battery line.The constraints brought by the TDMA mode are detailed, especially on the input filter of the BDR in presence of large battery inductance. The solution developed to cope with large TDMA current is then presented with the associated TDMA performance.

  10. Programmed Cell-to-Cell Variability in Ras Activity Triggers Emergent Behaviors during Mammary Epithelial Morphogenesis

    Directory of Open Access Journals (Sweden)

    Jennifer S. Liu

    2012-11-01

    Full Text Available Variability in signaling pathway activation between neighboring epithelial cells can arise from local differences in the microenvironment, noisy gene expression, or acquired genetic changes. To investigate the consequences of this cell-to-cell variability in signaling pathway activation on coordinated multicellular processes such as morphogenesis, we use DNA-programmed assembly to construct three-dimensional MCF10A microtissues that are mosaic for low-level expression of activated H-Ras. We find two emergent behaviors in mosaic microtissues: cells with activated H-Ras are basally extruded or lead motile multicellular protrusions that direct the collective motility of their wild-type neighbors. Remarkably, these behaviors are not observed in homogeneous microtissues in which all cells express the activated Ras protein, indicating that heterogeneity in Ras activity, rather than the total amount of Ras activity, is critical for these processes. Our results directly demonstrate that cell-to-cell variability in pathway activation within local populations of epithelial cells can drive emergent behaviors during epithelial morphogenesis.

  11. Distributed cooperative synchronization strategy for multi-bus microgrids

    DEFF Research Database (Denmark)

    Sun, Yao; Zhong, Chaolu; Hou, Xiaochao;

    2017-01-01

    synchronization methods based on centralized communication are very costly and not suitable for multi-bus microgrids that have a large number of distributed generators (DGs). To address this concern, this study presents an active synchronization control strategy based on distributed cooperation technology...... for multi-bus microgrids. The proposed method can reconnect the microgrid in island to UG seamlessly with sparse communication channels. Synchronization correction signals are generated by a voltage controller, which are only transmitted to the leader DGs. Meanwhile, each DG exchanges information with its...

  12. Persecution as a Theme in Isaac Bashevis Singer's The Bus

    Institute of Scientific and Technical Information of China (English)

    Wu Minzhi

    2008-01-01

    Isaac Bashevis Singer is very much concerned about the fate of Jewish people,so he often presents Jews'sufferings in his literary works.The Bus,by means of describing the narrator's experiences during a bus tour through Spain,in different dimensions reinforces the destructive impact of persecution that Jews have gone through.Moreover,he implies such persecution is not merely confined between Jews and the Gentile,but also spreads among the whole human beings who hold differet beliefs.

  13. The Bacillus cereus spoIIS programmed cell death system

    Directory of Open Access Journals (Sweden)

    Jana eMelnicakova

    2015-08-01

    Full Text Available Programmed cell death in bacteria is generally associated with two¬ component toxin antitoxin systems. The SpoIIS toxin-antitoxin system, consisting of a membrane bound SpoIISA toxin and a small, cytosolic antitoxin SpoIISB, was originally identified in Bacillus subtilis. In this work we describe the Bacillus cereus SpoIIS system which is a three-component system, harbouring an additional gene spoIISC. Its protein product serves as an antitoxin, and similarly as SpoIISB, is able to bind SpoIISA and abolish its toxic effect. Our results indicate that SpoIISC seems to be present not only in B. cereus but also in other Bacilli containing a SpoIIS toxin antitoxin system. In addition, we show that B. cereus SpoIISA can form higher oligomers and we discuss the possible role of this multimerization for the protein’s toxic function.

  14. Programmed cell death in developing human fetal CNS

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    The spatial and temporal distributions of programmed cell death (PCD) in developing central nervous system (CNS) of human fetuses ranging from 12 to 39 weeks of gestation were investigated using techniques of flow cytometry and terminal transferase-mediated nick end labeling (TUNEL). The results showed that PCD did occur in every representative brain region of all fetuses examined in different stages. It was found that there were two peaks of PCD appearing at the 12th and 39th weeks respectively, which suggested that the first peak of apoptosis may be involved in the selective elimination of neurons overproduced during the early development and the second may play an important role in establishing the correct neuronal circuitry.

  15. Improving student bus-riding behavior through a whole-school intervention.

    OpenAIRE

    Putnam, Robert F; Handler, Marcie W; Ramirez-Platt, Christina M; Luiselli, James K

    2003-01-01

    We describe a multicomponent intervention to improve bus-riding behavior of students attending an urban public school. The intervention was developed with technical assistance consultation that emphasized collaboration among students, school personnel, and bus drivers. The primary intervention procedures were identifying appropriate behaviors during transportation ("bus rules"), training bus drivers to deliver positive reinforcement, and rewarding student performance through a weekly school-b...

  16. Bus Catcher: A Context Sensitive Prototype System for Public Transportation Users

    OpenAIRE

    Bertolotto, Michela; O'Hare, G.M.P.; Strahan, Robin; Brophy, Ailish; Martin, A.; McLoughlin, Eoin

    2002-01-01

    In this paper we describe the architectural and functional characteristics of Bus Catcher, a context sensitive prototype system for public transportation users. Bus Catcher assists mobile users in planning their bus rides by providing timely and accurate information about current bus locations and estimated arrival times. A complete report on the implementation together with a preliminary evaluation of the system is provided in this paper.

  17. Performance evaluation of UHF RFID technologies for real-time bus recognition in the Taipei Bus Station.

    Science.gov (United States)

    Own, Chung-Ming; Lee, Da-Sheng; Wang, Ti-Ho; Wang, De-Jun; Ting, Yu-Lun

    2013-06-18

    Transport stations such as airports, ports, and railways have adopted blocked-type pathway management to process and control travel systems in a one-directional manner. However, this excludes highway transportation where large buses have great variability and mobility; thus, an instant influx of numerous buses increases risks and complicates station management. Focusing on Taipei Bus Station, this study employed RFID technology to develop a system platform integrated with modern information technology that has numerous characteristics. This modern information technology comprised the following systems: ultra-high frequency (UHF) radio-frequency identification (RFID), ultrasound and license number identification, and backstage graphic controls. In conclusion, the system enabled management, bus companies, and passengers to experience the national bus station's new generation technology, which provides diverse information and synchronization functions. Furthermore, this technology reached a new milestone in the energy-saving and efficiency-increasing performance of Taiwan's buses.

  18. The Molecular Ecophysiology of Programmed Cell Death in Marine Phytoplankton

    Science.gov (United States)

    Bidle, Kay D.

    2015-01-01

    Planktonic, prokaryotic, and eukaryotic photoautotrophs (phytoplankton) share a diverse and ancient evolutionary history, during which time they have played key roles in regulating marine food webs, biogeochemical cycles, and Earth's climate. Because phytoplankton represent the basis of marine ecosystems, the manner in which they die critically determines the flow and fate of photosynthetically fixed organic matter (and associated elements), ultimately constraining upper-ocean biogeochemistry. Programmed cell death (PCD) and associated pathway genes, which are triggered by a variety of nutrient stressors and are employed by parasitic viruses, play an integral role in determining the cell fate of diverse photoautotrophs in the modern ocean. Indeed, these multifaceted death pathways continue to shape the success and evolutionary trajectory of diverse phytoplankton lineages at sea. Research over the past two decades has employed physiological, biochemical, and genetic techniques to provide a novel, comprehensive, mechanistic understanding of the factors controlling this key process. Here, I discuss the current understanding of the genetics, activation, and regulation of PCD pathways in marine model systems; how PCD evolved in unicellular photoautotrophs; how it mechanistically interfaces with viral infection pathways; how stress signals are sensed and transduced into cellular responses; and how novel molecular and biochemical tools are revealing the impact of PCD genes on the fate of natural phytoplankton assemblages.

  19. MSCT findings in a controlled bus bombing using a pig model

    DEFF Research Database (Denmark)

    Hansen, Nikolaj Friis

    2009-01-01

    pig's position in the bus at the time of detonation. 1 of the pigs was rigged as a suicide bomber while the others were individually placed as passengers and bus driver inside the bus alongside dummies. Measurements of the blast force and fast speed video recordings were made during the detonation...

  20. 49 CFR 571.221 - Standard No. 221; School bus body joint strength.

    Science.gov (United States)

    2010-10-01

    ... means any part of the bus, of either a mechanical or electrical nature, which is explicitly identified... 49 Transportation 6 2010-10-01 2010-10-01 false Standard No. 221; School bus body joint strength... STANDARDS Federal Motor Vehicle Safety Standards § 571.221 Standard No. 221; School bus body joint...

  1. 46 CFR 112.05-3 - Main-emergency bus-tie.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 4 2010-10-01 2010-10-01 false Main-emergency bus-tie. 112.05-3 Section 112.05-3 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) ELECTRICAL ENGINEERING EMERGENCY LIGHTING AND POWER SYSTEMS General § 112.05-3 Main-emergency bus-tie. Each bus-tie between a main...

  2. Anhydrobiosis and programmed cell death in plants: Commonalities and Differences

    Directory of Open Access Journals (Sweden)

    Samer Singh

    2015-05-01

    Full Text Available Anhydrobiosis is an adaptive strategy of certain organisms or specialised propagules to survive in the absence of water while programmed cell death (PCD is a finely tuned cellular process of the selective elimination of targeted cell during developmental programme and perturbed biotic and abiotic conditions. Particularly during water stress both the strategies serve single purpose i.e., survival indicating PCD may also function as an adaptive process under certain conditions. During stress conditions PCD cause targeted cells death in order to keep the homeostatic balance required for the organism survival, whereas anhydrobiosis suspends cellular metabolic functions mimicking a state similar to death until reestablishment of the favourable conditions. Anhydrobiosis is commonly observed among organisms that have ability to revive their metabolism on rehydration after removal of all or almost all cellular water without damage. This feature is widely represented in terrestrial cyanobacteria and bryophytes where it is very common in both vegetative and reproductive stages of life-cycle. In the course of evolution, with the development of advanced vascular system in higher plants, anhydrobiosis was gradually lost from the vegetative phase of life-cycle. Though it is retained in resurrection plants that primarily belong to thallophytes and a small group of vascular angiosperm, it can be mostly found restricted in orthodox seeds of higher plants. On the contrary, PCD is a common process in all eukaryotes from unicellular to multicellular organisms including higher plants and mammals. In this review we discuss physiological and biochemical commonalities and differences between anhydrobiosis and PCD.

  3. IMPROVEMENT OF BUS OPERATIONAL CHARACTERISTICS WHILE USING INTEGRATED CONTROL OF SUSPENSION AND TRANSMISSION

    Directory of Open Access Journals (Sweden)

    V. V. Mikhailau

    2016-01-01

    Full Text Available Semi-natural tests for active pneumatic suspension of a 18-tonne tourist bus with the system of automatic body stabilization of the mobile machine and feed-back coupling according to kinematics parameter. The test have been executed in the cases when the bus is stocked with an automatic hydro-mechanical transmission in the process of speed picking up, gear-changing or road braking which is assigned by accidental road humps. A computer simulation of dynamic structures in combination with virtual devices and real objects (HIL – Hardware-in-the-Loop Simulation has been carried in the paper. Personal computers, software, programmed logic controller, frequency generator, solenoid-operated valve have been used for the investigation process. The paper proposes an unconventional method for improvement operational characteristics which is based on integrated control of a suspension and automatic hydro-mechanical transmission. A mathematical model includes systems of automatic transmission, suspension and module for generation of accidental road humps. The model has been considered as a basis for semi-natural laboratory bench with industrially-manufactured controller, other components of automatic systems and standard control organs. The most efficient method for body stabilization is control of the suspension according to the parameter of angular rate during vertical turn of an automobile’s center line with a turning point in the center of mass. The developed algorithm and stabilization system according to angular rate of body’s center line turning have made it possible to improve dynamics of the bus while making gear-changing and to reduce fuel consumption during starting-up and speed picking-up processes. During the braking process such system simultaneously decreases oscillation amplitude of some parameters more than two-fold.

  4. Bullying on the School Bus: A Video Analysis

    Science.gov (United States)

    Raskauskas, Juliana

    2005-01-01

    The purpose of this study was to assess the nature of bullying on the school bus. Videotapes were used to identify occurrences of bullying on buses of elementary school students. Incidents were reviewed for forms of bullying, fullness, presence of friends, and severity of acts. Results indicated that approximately two incidents occurred per bus…

  5. Bussikontsern Go Bus ihaldab Harjumaa turgu / Signe Kalberg

    Index Scriptorium Estoniae

    Kalberg, Signe, 1959-

    2005-01-01

    AS-i Tarbus ja kaheksa bussiettevõtte ühinemisel moodustati AS Go Bus, ettevõte plaanib veel mitme bussifirma liitmist. Atko Grupi juhatuse esimehe Margo Tomingase, AS Sebe nõukogu esimehe Hugo Osula arvamus. Lisa: Konkurentsiamet hoiab silma peal

  6. Overview of Multi-DC-Bus Solutions for DC Microgrids

    DEFF Research Database (Denmark)

    Ricchiuto, D.; Mastromauro, R.A.; Liserre, Marco;

    2013-01-01

    DC Microgrids have recently received a lot of attention in the last years due to high penetration of renewable energy sources as well as distributed energy storage systems. In the future DC microgrids could be preferable respect to AC microgrids in terms of redundancy since multi-DC-Bus solutions...

  7. What's Happening on the School Bus Performance Front?

    Science.gov (United States)

    Combs, Hanford L.

    The most urgent order of business in the national scene is to complete the development of a series of new performance tests for school bus bodies and chassis to establish a benchmark for safe construction that can be verified by independent testing agencies. Such performance tests should incorporate the new Federal Joint Strength Efficiency…

  8. High-Tech School Bus Teaches Students on the Road

    Science.gov (United States)

    Katims, Lauren

    2011-01-01

    Last year, kindergarten through high school students in the rural Hector, Arkansas, School District barely had the technology resources that keep kids interested in math and science. This year, they potentially have the most advanced resources in the country--before they even step into the classroom. One school bus in Arkansas' Pope County has…

  9. A Novel Time Synchronization Method for Dynamic Reconfigurable Bus

    Directory of Open Access Journals (Sweden)

    Zhang Weigong

    2016-01-01

    Full Text Available UM-BUS is a novel dynamically reconfigurable high-speed serial bus for embedded systems. It can achieve fault tolerance by detecting the channel status in real time and reconfigure dynamically at run-time. The bus supports direct interconnections between up to eight master nodes and multiple slave nodes. In order to solve the time synchronization problem among master nodes, this paper proposes a novel time synchronization method, which can meet the requirement of time precision in UM-BUS. In this proposed method, time is firstly broadcasted through time broadcast packets. Then, the transmission delay and time deviations via three handshakes during link self-checking and channel detection can be worked out referring to the IEEE 1588 protocol. Thereby, each node calibrates its own time according to the broadcasted time. The proposed method has been proved to meet the requirement of real-time time synchronization. The experimental results show that the synchronous precision can achieve a bias less than 20 ns.

  10. Platform Screen Doors Enhanced Bus Rapid Transit Intelligent Performance

    Directory of Open Access Journals (Sweden)

    Chonghua Zhou

    2011-06-01

    Full Text Available It is the last straw to clutch at to solve the urban traffic issue, to develop high-capacity rapid transit and promote transit priority. Characterized by low cost, short construction cycle and flexible development, Bus Rapid Transit (BRT has been favored by more and more cities in the world. The Platform Screen Doors (PSDs system is an important component at BRT stations, and it is original motive to be designed to satisfy the growing demand from BRT application to provide increased safety and comfort in the first. With the continual increased demand for BRT intelligent performance, the PSDs system is applied to get Bus Location Information with accurate position of arrival and departure at stop, to provide Real-Time Information (RTI for BRT passengers using PSDs/GPS compound location technology, to put into practice Bus Fleet Management (BFM. Considering the capability of accurate location, it can be applied to actualize Bus Sign Priority in the future. The authors are luck to take in part the practice of BRT system, especially in the BRT intelligent systems, the papers will introduce upwards application and conceive in detail.

  11. Measurements on and simulations of a biogas-fuelled bus

    International Nuclear Information System (INIS)

    Mathematical models for torque/fuel consumption and emissions have been studied for a biogas-fuelled bus used in urban traffic in Linkoeping, Sweden. It is noted that the cycle ECE R-49 is not representative for city buses, but that the Braunschweig cycle gives rather good agreement. 2 refs, 37 figs

  12. Measuring Bus Drivers' Occupational Stress Under Changing Working Conditions

    NARCIS (Netherlands)

    Hlotova, Y.; Cats, O.; Meijer, S.A.

    2014-01-01

    Stress is an immense problem in modern society; approximately half of all occupational illnesses are directly or indirectly related to stress. The work of a bus driver is typically associated with high stress levels that negatively influence individual well-being as well as workforce management. The

  13. Programmed cell death features in apple suspension cells under low oxygen culture

    Institute of Scientific and Technical Information of China (English)

    XU Chang-jie(徐昌杰); CHEN Kun-song(陈昆松); FERGUSON Ian B.

    2004-01-01

    Suspension-cultured apple fruit cells (Malus pumila Mill. cv. Braeburn) were exposed to a low oxygen atmosphere to test whether programmed cell death (PCD) has a role in cell dysfunction and death under hypoxic conditions. Protoplasts were prepared at various times after low oxygen conditions were established, and viability tested by triple staining with fluorescein diacetate (FDA), propidium iodide (PI) and Hoechst33342 (HO342). DNA breakdown and phosphatidylserine exposure on the plasma membrane were observed using terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL), and annexin V binding. About 30% of protoplasts from cells after 48 h under low oxygen showed an increased accumulation of HO342, indicating increased membrane permeability. Positive TUNEL and annexin V results were also only obtained with protoplasts from cells under low oxygen. The results suggest that apple cell death under low oxygen is at least partially PCD mediated, and may explain tissue breakdown under controlled atmosphere (low oxygen) conditions in apple fruit.

  14. GeoBus: sharing science research with schools

    Science.gov (United States)

    Roper, Kathryn; Robinson, Ruth; Moorhouse, Ben

    2016-04-01

    GeoBus (www.geobus.org.uk) is an educational outreach project that was developed in 2012 by the Department of Earth and Environmental Sciences at the University of St Andrews, and it is currently sponsored by industry, NERC, The Crown Estate, and the Scottish Government. The aims of GeoBus are to support the teaching of Earth Science in secondary (middle and high) schools by providing teaching support to schools that have little or no experience in teaching this subject. This is, in part, done through the sharing of new science research outcomes and the experiences of young researchers with school pupils to provide a bridge between industry, higher education institutions, research councils and schools. Since its launch, over 40,000 pupils will have been involved in experiential Earth science learning activities in 190 different schools (over 400 separate visits) across the length and breadth of Scotland: many of these schools are in remote and disadvantaged regions. A new GeoBus project is under development within the Department of Earth Sciences at UCL in London. A key aim of GeoBus is to incorporate new research into our workshops with the main challenge being the development of appropriate resources that incorporate the key learning aims and requirements of the science and geography curricula. GeoBus works closely with researchers, teachers and educational practitioners to tailor the research outcomes to the curricula as much as possible. Over the past four years, GeoBus has developed 17 workshops, 5 challenge events and extensive field trips and each of these activities are trialled and evaluated within the university, and adjustments are made before the activities are delivered in schools. Activities are continually reviewed and further developments are made in response to both teacher and pupil feedback. This critical reflection of the project's success and impact is important to insure a positive and significant contribution to the science learning in

  15. Energy Performance Optimization of a Bus for Urban Public Transport

    Directory of Open Access Journals (Sweden)

    Paola Gori

    2013-08-01

    Full Text Available Nowadays many people use public transports in urban centres. Consequently, every day a lot of buses move within cities, trying to ensure the best service to citizens. During the year buses becomecrowded places and using an air conditioning system in constant operation, it tries to ensure a certain condition of comfort for the passengers on board. The aim of this study is to analyse and optimize the energy performance of a bus shell, identifying practical solutions that have not yet been adopted in order to reduce the impact of air conditioning on bus consumption and, therefore, on air pollution. For this reason it was decided to conduct a thermal analysis of a bus for public transport, in order to understandthe behaviour of the bus shell and to deduce possible optimization measures that have not yet been made until now. The analysis was carried out considering the hottest day of July and the coldest day ofJanuary, considering the conditions of operation based on the most common graphics TGM able to define the concentration of traffic city during the 24 hours per day. The study was done using the dynamicsimulation software TRNSYS. With this software it was possible to recreate faithfully the structure of the bus and the external environmental conditions, assessing the impact of different technical solutions for an improvement of internal conditions and a reduction of the cooling capacity required. Because the presence of passengers in public transport is considered like a “benefit” during the winter, the analysis started with the identification of a summer solution and the subsequent evaluation of this solution for the wintertime. The aim of this study was to optimize the bus shell and select the most appropriate solutions. Regarding the transparent surfaces it has been given importance to factors such as the thermal transmittance and the solar gain factor (g-value. Aware of the influence given by the solar radiation on the energy loads, we

  16. 2011 Annual Progress Report: DOE Hydrogen and Fuel Cells Program (Book)

    Energy Technology Data Exchange (ETDEWEB)

    2011-11-01

    In the past year, the DOE Hydrogen and Fuel Cells Program (the Program) made substantial progress toward its goals and objectives. The Program has conducted comprehensive and focused efforts to enable the widespread commercialization of hydrogen and fuel cell technologies in diverse sectors of the economy. With emphasis on applications that will effectively strengthen our nation's energy security and improve our stewardship of the environment, the Program engages in research, development, and demonstration of critical improvements in the technologies. Highlights of the Program's accomplishments can be found in the sub-program chapters of this report.

  17. Pathways to Commercial Success. Technologies and Products Supported by the Fuel Cell Technologies Program

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2010-08-01

    This report identifies the commercial and near-commercial (emerging) hydrogen and fuel cell technologies and products that resulted from Department of Energy support through the Fuel Cell Technologies Program in the Office of Energy Efficiency and Renewable Energy.

  18. Potential for cell therapy in Parkinson's disease using genetically programmed human embryonic stem cell-derived neural progenitor cells.

    Science.gov (United States)

    Ambasudhan, Rajesh; Dolatabadi, Nima; Nutter, Anthony; Masliah, Eliezer; Mckercher, Scott R; Lipton, Stuart A

    2014-08-15

    Neural transplantation is a promising strategy for restoring dopaminergic dysfunction and modifying disease progression in Parkinson's disease (PD). Human embryonic stem cells (hESCs) are a potential resource in this regard because of their ability to provide a virtually limitless supply of homogenous dopaminergic progenitors and neurons of appropriate lineage. The recent advances in developing robust cell culture protocols for directed differentiation of hESCs to near pure populations of ventral mesencephalic (A9-type) dopaminergic neurons has heightened the prospects for PD cell therapy. Here, we focus our review on current state-of-the-art techniques for harnessing hESC-based strategies toward development of a stem cell therapeutic for PD. Importantly, we also briefly describe a novel genetic-programming approach that may address many of the key challenges that remain in the field and that may hasten clinical translation.

  19. Efficient and Robust Data Collection Using Compact Micro Hardware, Distributed Bus Architectures and Optimizing Software

    Science.gov (United States)

    Chau, Savio; Vatan, Farrokh; Randolph, Vincent; Baroth, Edmund C.

    2006-01-01

    Future In-Space propulsion systems for exploration programs will invariably require data collection from a large number of sensors. Consider the sensors needed for monitoring several vehicle systems states of health, including the collection of structural health data, over a large area. This would include the fuel tanks, habitat structure, and science containment of systems required for Lunar, Mars, or deep space exploration. Such a system would consist of several hundred or even thousands of sensors. Conventional avionics system design will require these sensors to be connected to a few Remote Health Units (RHU), which are connected to robust, micro flight computers through a serial bus. This results in a large mass of cabling and unacceptable weight. This paper first gives a survey of several techniques that may reduce the cabling mass for sensors. These techniques can be categorized into four classes: power line communication, serial sensor buses, compound serial buses, and wireless network. The power line communication approach uses the power line to carry both power and data, so that the conventional data lines can be eliminated. The serial sensor bus approach reduces most of the cabling by connecting all the sensors with a single (or redundant) serial bus. Many standard buses for industrial control and sensor buses can support several hundreds of nodes, however, have not been space qualified. Conventional avionics serial buses such as the Mil-Std-1553B bus and IEEE 1394a are space qualified but can support only a limited number of nodes. The third approach is to combine avionics buses to increase their addressability. The reliability, EMI/EMC, and flight qualification issues of wireless networks have to be addressed. Several wireless networks such as the IEEE 802.11 and Ultra Wide Band are surveyed in this paper. The placement of sensors can also affect cable mass. Excessive sensors increase the number of cables unnecessarily. Insufficient number of sensors

  20. Programmed cell death features in apple suspension cells under low oxygen culture

    Institute of Scientific and Technical Information of China (English)

    徐昌杰; 陈昆松; FERGUSONIanB

    2004-01-01

    Suspension-cultured apple fruit cells (Malus pumila Mill. cv. Braeburn) were exposed to a low oxygen atmosphere to test whether programmed cell death (PCD) has a role in cell dysfunction and death under hypoxic conditions. Protoplasts were prepared at various times after low oxygen conditions were established, and viability tested by triple staining with fluorescein diacetate (FDA), propidium iodide (PI) and Hoechst33342 (HO342). DNA breakdown and phosphatidylserine exposure on the plasma membrane were observed using terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling (TUNEL), and annexin V binding. About 30% of protoplasts from cells after 48 h under low oxygen showed an increased accumulation of HO342, indicating increased membrane permeability. Positive TUNEL and annexin V results were also only obtained with protoplasts from cells under low oxygen. The results suggest that apple celi death under low oxygen is at least partially PCD mediated, and may explain tissue breakdown under controlled atmosphere (low oxygen) conditions in apple fruit.

  1. Two hot spots in China's bus market%中国客车市场呈现两大热点

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    @@ According to an analysis on statistics of production and sales of China's 70 bus enterprises in 2005, bus sales are expected to continue to grow this year, posing a better performance than that in the previous year, and the urban public bus transport, rural bus transport and export together will be a major motive power for pulling up growth of the industry.

  2. Regulation of programmed cell death by plasminogen activator inhibitor type 1 (PAI-1)

    DEFF Research Database (Denmark)

    Lademann, Ulrik Axel; Rømer, Maria Unni Koefoed

    2008-01-01

    PA) observed in tumours; however, several lines of evidence suggest that PAI-1 may contribute directly to the pathology of the disease. PAI-1 has been reported to have an effect on most of the basic cellular processes including cell adhesion, cell migration, cell invasion, and cell proliferation and increasing...... numbers of reports suggest that PAI-1 also can regulate programmed cell death (PCD) in cancer cells and normal cells. A number of reports suggest that PAI-1 can inhibit PCD through its pro-adhesive/anti-proteolytic property whereas other reports suggest that PAI-1 induces PCD through its anti......-adhesive property.Furthermore,it has been suggested that PAI-1 can either induce or inhibit PCD though activation of cell signalling pathways.This review will focus on the regulation of programmed cell death by PAI-1 in both normal cells and cancer cells....

  3. 2015 DOE Hydrogen and Fuel Cells Program Annual Merit Review and Peer Evaluation Report

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2015-10-01

    This report summarizes comments from the Peer Review Panel at the 2015 DOE Hydrogen and Fuel Cells Program Annual Merit Review, held on June 8-12, 2015, in Arlington, Virginia. It covers the program areas of hydrogen production and delivery; hydrogen storage; fuel cells; manufacturing R&D; technology validation; safety, codes, and standards; market transformation; and systems analysis.

  4. 2014 DOE Hydrogen and Fuel Cells Program Annual Merit Review and Peer Evaluation Report

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2014-10-01

    This report summarizes comments from the Peer Review Panel at the 2014 DOE Hydrogen and Fuel Cells Program Annual Merit Review, held on June 16-20, 2014, in Washington, DC. It covers the program areas of hydrogen production and delivery; hydrogen storage; fuel cells; manufacturing R&D; technology validation; safety, codes, and standards; market transformation; and systems analysis.

  5. 2011 DOE Hydrogen and Fuel Cells Program Annual Merit Review and Peer Evaluation Report

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2011-09-01

    This report summarizes comments from the Peer Review Panel at the 2011 DOE Hydrogen and Fuel Cells Program Annual Merit Review, held on May 9-13, 2011, in Arlington, Virginia. It covers the program areas of hydrogen production and delivery; hydrogen storage; fuel cells; manufacturing R&D; technology validation; safety, codes, and standards; education; market transformation; and systems analysis.

  6. 2013 DOE Hydrogen and Fuel Cells Program Annual Merit Review and Peer Evaluation Report

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2013-10-01

    This report summarizes comments from the Peer Review Panel at the 2013 DOE Hydrogen and Fuel Cells Program Annual Merit Review, held on May 13-17, 2013, in Arlington, Virginia. It covers the program areas of hydrogen production and delivery; hydrogen storage; fuel cells; manufacturing R&D; technology validation; safety, codes, and standards; market transformation; and systems analysis.

  7. 2012 DOE Hydrogen and Fuel Cells Program Annual Merit Review and Peer Evaluation Report

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2012-09-01

    This report summarizes comments from the Peer Review Panel at the 2012 DOE Hydrogen and Fuel Cells Program Annual Merit Review, held on May 14-18, 2012, in Arlington, Virginia. It covers the program areas of hydrogen production and delivery; hydrogen storage; fuel cells; manufacturing R&D; technology validation; safety, codes, and standards; education; market transformation; and systems analysis.

  8. Death of mitochondria during programmed cell death of leaf mesophyll cells.

    Science.gov (United States)

    Selga, Tūrs; Selga, Maija; Pāvila, Vineta

    2005-12-01

    The role of plant mitochondria in the programmed cell death (PCD) is widely discussed. However, spectrum and sequence of mitochondrial structural changes during different types of PCD in leaves are poorly described. Pea, cucumber and rye plants were grown under controlled growing conditions. A part of them were sprinkled with ethylene releaser to accelerate cell death. During yellowing the palisade parenchyma mitochondria were attracted to nuclear envelope. Mitochondrial matrix became electron translucent. Mitochondria entered vacuole by invagination of tonoplast and formed multivesicular bodies. Ethephon treatment increased the frequency of sticking of mitochondria to the nuclear envelope or chloroplasts and peroxisomes. Mitochondria divided by different mechanisms and became enclosed in Golgi and ER derived authopagic vacuoles or in the central vacuole. Several fold increase of the diameter of cristae became typical. In all cases mitochondria were attached to nuclear envelope. It can be considered as structural mechanism of promoting of PCD.

  9. Bus Technology and Its Application of Microchip UNI/O%MicrochipUNI/O总线技术及其应用

    Institute of Scientific and Technical Information of China (English)

    汪社民

    2012-01-01

    UNI/O总线是Microchip公司开发的一种创新型单I/0总线。本文分析了该总线的特点和通信原理,以11XXX系列EEPROM存储器的应用为例,详细介绍了UNI/O从器件与单片机的接口技术,给出了硬件连接电路和存储器读写操作的程序流程。%UNI/O bus is an innovative single-I/O bus developed by Microchip. The paper analyzes the features and communication princi pie of UNI/O bus. Taking the application of 11XXX serial EEPROM memeory an example, the article describes the interface technology of UNI/O slave device and MCU in detail. Then the hardware connection circuit and program flow of memory read and write operation are provided.

  10. An application programming interface for CellNetAnalyzer.

    Science.gov (United States)

    Klamt, Steffen; von Kamp, Axel

    2011-08-01

    CellNetAnalyzer (CNA) is a MATLAB toolbox providing computational methods for studying structure and function of metabolic and cellular signaling networks. In order to allow non-experts to use these methods easily, CNA provides GUI-based interactive network maps as a means of parameter input and result visualization. However, with the availability of high-throughput data, there is a need to make CNA's functionality also accessible in batch mode for automatic data processing. Furthermore, as some algorithms of CNA are of general relevance for network analysis it would be desirable if they could be called as sub-routines by other applications. For this purpose, we developed an API (application programming interface) for CNA allowing users (i) to access the content of network models in CNA, (ii) to use CNA's network analysis capabilities independent of the GUI, and (iii) to interact with the GUI to facilitate the development of graphical plugins. Here we describe the organization of network projects in CNA and the application of the new API functions to these projects. This includes the creation of network projects from scratch, loading and saving of projects and scenarios, and the application of the actual analysis methods. Furthermore, API functions for the import/export of metabolic models in SBML format and for accessing the GUI are described. Lastly, two example applications demonstrate the use and versatile applicability of CNA's API. CNA is freely available for academic use and can be downloaded from http://www.mpi-magdeburg.mpg.de/projects/cna/cna.html.

  11. An application programming interface for CellNetAnalyzer.

    Science.gov (United States)

    Klamt, Steffen; von Kamp, Axel

    2011-08-01

    CellNetAnalyzer (CNA) is a MATLAB toolbox providing computational methods for studying structure and function of metabolic and cellular signaling networks. In order to allow non-experts to use these methods easily, CNA provides GUI-based interactive network maps as a means of parameter input and result visualization. However, with the availability of high-throughput data, there is a need to make CNA's functionality also accessible in batch mode for automatic data processing. Furthermore, as some algorithms of CNA are of general relevance for network analysis it would be desirable if they could be called as sub-routines by other applications. For this purpose, we developed an API (application programming interface) for CNA allowing users (i) to access the content of network models in CNA, (ii) to use CNA's network analysis capabilities independent of the GUI, and (iii) to interact with the GUI to facilitate the development of graphical plugins. Here we describe the organization of network projects in CNA and the application of the new API functions to these projects. This includes the creation of network projects from scratch, loading and saving of projects and scenarios, and the application of the actual analysis methods. Furthermore, API functions for the import/export of metabolic models in SBML format and for accessing the GUI are described. Lastly, two example applications demonstrate the use and versatile applicability of CNA's API. CNA is freely available for academic use and can be downloaded from http://www.mpi-magdeburg.mpg.de/projects/cna/cna.html. PMID:21315797

  12. StarBus+: Distributed Object Middleware Practice for Internet Computing

    Institute of Scientific and Technical Information of China (English)

    Huai-Min Wang; Yu-Feng Wang; Yang-Bin Tang

    2005-01-01

    In the past decade, the booming of Internet challenges the middleware in three aspects: quality of service,balance of changes and stabilization, and across-Internet integration. This paper presents our work on distributed object computing middleware technology for these challenges, as well as the research and development on StarBus+, which is a CORBA standard-compliant middleware suite with the features such as object request broker supporting multi-* quality of service, component model, and integration with Web Service. This paper comprehensively presents the design and characteristics of StarBns+, and demonstrates how StarBus+ is enhanced to address the challenges of Internet computing through three case studies: inter-enterprise integration over Internet, application evolution through dynamic reconfiguration,and great massive information system building. The paper also suggests some research directions which are important for Internet computing.

  13. Bus Encoder for Crosstalk Avoidance in RLC Modeled Interconnects

    Directory of Open Access Journals (Sweden)

    G. Nagendra Babu

    2012-02-01

    Full Text Available Most of the encoding methods proposed in recent years have dealt with only RC modeled VLSI interconnects. For deep sub micron technologies (DSM, on-chip inductive effects have increased due to faster clock speeds, smaller signal rise times and longer length of on-chip interconnects. All these issues raise the concern for cross talk, propagation delay and power dissipation of overall. Therefore, this research work introduces an efficient Bus Encoder using Bus Inverting (BI method. The proposed design dramatically reduces both cross talk and power dissipation in RLC modeled interconnects which makes it suitable for current high-speed low-power VLSI interconnects. The proposed model demonstrates an overall reduction of power dissipation and cross talk induced delay by 55.43% and 45.87%, respectively.

  14. Bus Vent Design Evolution for the Solar Dynamics Observatory

    Science.gov (United States)

    Woronowicz, Michael

    2010-01-01

    As a spacecraft undergoes ascent in a launch vehicle, its pressure environment transitions from one atmosphere to high vacuum in a matter of minutes. Venting of internal cavities is necessary to prevent the buildup of pressure differentials across cavity walls. Opposing the need to vent these volumes freely into space are thermal, optical, and electrostatic requirements for limiting or prohibiting the intrusion of unwanted energy into the same cavities. Bus vent design evolution is discussed for the Solar Dynamics Observatory. Design changes were influenced by a number of factors and concerns, such as contamination control, electrostatic discharge, changes in bus material, and driving fairing ascent pressure for a launch vehicle that was just entering service as this satellite project had gotten underway.

  15. Implementation of I 2C Master Bus Protocol on FPGA

    Directory of Open Access Journals (Sweden)

    Regu Archana

    2014-10-01

    Full Text Available The focus of this paper is on I 2C (Inter-Integrated Circuit protocol interface between Master Bus protocol and slave. Here we are interfacing between micro-controller and DS1307. I 2C bus protocol sends 8 bit data from micro-controller to DS1307. This module was designed in VHDL and simulated and synthesized using Xilinx ISE Design Suite 14.2. I 2C and optimized for area and power. This concept is widely applicable from any high speed device or low speed device to any low speed device or high speed device. This module acts as a slave for the DS1307 at the same time acts like a master for the micro-controller device which can be considered as a slave. . It can be used to interface low speed peripherals like motherboard, embedded system, mobile phones, set top boxes, DVD, PDA’s or other electronic devices.

  16. Hardware Engines for Bus Encryption: A Survey of Existing Techniques

    CERN Document Server

    Elbaz, R; Sassatelli, G; Guillemin, P; Anguille, C; Bardouillet, M; Buatois, C; Rigaud, J B

    2011-01-01

    The widening spectrum of applications and services provided by portable and embedded devices bring a new dimension of concerns in security. Most of those embedded systems (pay-TV, PDAs, mobile phones, etc...) make use of external memory. As a result, the main problem is that data and instructions are constantly exchanged between memory (RAM) and CPU in clear form on the bus. This memory may contain confidential data like commercial software or private contents, which either the end-user or the content provider is willing to protect. The goal of this paper is to clearly describe the problem of processor-memory bus communications in this regard and the existing techniques applied to secure the communication channel through encryption - Performance overheads implied by those solutions will be extensively discussed in this paper.

  17. Environmental assessment of 9 European public bus transportation systems

    DEFF Research Database (Denmark)

    Nanaki, Eva; Koroneos, Christophis; Roset, Jaume;

    2017-01-01

    that affect the production of carbon dioxide (CO2) as well as of air pollutants, in 9 major European cities, aiming to provide a comprehensive overview of the actual knowledge on the atmospheric pollution from public transportation systems. CO2 emissions as well as air pollutants, such as CO, HC, PM, NOx......The transportation sector is one of the largest sources of EU’s greenhouse gas emissions. In 2011, transportation represented approximately 25 percent of total EU’s greenhouse gas emissions. Urban mobility accounts for 40% of all CO2 emissions of road transport and up to 70% of other pollutants...... are calculated for the diesel and CNG bus fleets of the European cities under study. Finally the environmental benefits, in terms of CO2 and CO, HC, PM, NOx emissions reductions, from the penetration of different biodiesel blends (from B10 to B100) to the bus fleets are estimated....

  18. Health effect of a bus ride in an urban environment

    Energy Technology Data Exchange (ETDEWEB)

    Takano, T.

    1983-07-01

    Health effects on subjects during a bus drive on an urban road were investigated in a real situation. Leukocyte count, adrenalin level in blood and urine, noradrenalin and dopamine in urine, diastolic blood pressure, and index of vascular resistance increased significantly on the drive day compared with the control day. A bus drive on an urban road induced enhanced sympathetic-adreno-medullary activity in real life as a result of the comprehensive effect of various factors. The concentrations of air pollutants were excessively high on the road, and correlated with traffic volume. It was concluded that the interactions between psychogenic, physical nonspecific and physical specific effects should be taken into consideration when evaluating human health effects of air pollution in the urban environment.

  19. THE DESIGN OF VMEBUS BRIDGE CONTROLLER WITH SHARC BUS

    Institute of Scientific and Technical Information of China (English)

    Wang Min; Wu Shunjun; Su Tao

    2005-01-01

    Targeting at the high expense and inflexibility to realize VMEbus bridge controller by professional Integrated Circuit (IC), this paper presents a scheme of adopting CPLD/FPGA (Complicated Programmable Logic Device/Field Programmable Gate Array) to design bridge controller between VMEbus and local bus. SHARC DSP (Digital Signal Processor) bus is an example. It has functions of nearly entire master/slave interface of VMEbus, and can act as DMA (Direct Memory Access) controller and perform block transfer in DMA or master processor initiative way without length limit. External circuit of the design is very simple. In comparison with special ICs, it has high performance to price ratio and can be easily applied to local buses of other processors with quite a little modification.

  20. Technology Update of a Control System Trough Corba Bus

    CERN Document Server

    Bertocchi, A; Buceti, G; Centioli, C; Muzio, D D; Iannone, F; Mazza, G; Panella, M; Vitale, V

    2001-01-01

    After more than 10 years of activity, FTU (Frascati Tokamak Upgrade) has to face the problem of taking advantage of the new hardware and software technology saving all the investments yet done. So, for example, the 20 years old Westinghouse PLCs (communicating only through a serial line) have to be leaved in operation while a web-based tool has to be released for plan monitoring purpose. CORBA bus has been demonstrated to be the answer to set up the communication between old and new hardware and software blocks. On FTU the control system is based on Basestar, a Digital/Compaq software suite. We will describe how the real time database of Basestar is now accessed by Java graphic tools, LabView and, in principle, any package accepting external routines. An account will be also done in the data acquisition area where a Camac serial highway driver has been integrated in the new architecture still through the CORBA bus

  1. Heat storage for a bus petrol internal-combustion engine

    Science.gov (United States)

    Vasiliev, Leonard L.; Burak, Victor S.; Kulakov, Andry G.; Mishkinis, Donatas A.; Bohan, Pavel V.

    The heat storage (HS) system for pre-heating a bus petrol internal combustion engine to starting was mathematically modelled and experimentally investigated. The development of such devices is an extremely urgent problem especially for regions with a cold climate. We discuss how HS works on the effect of absorption and rejection of heat energy at a solid-liquid phase change of a HS substance. In the first part of the paper a numerical method to calculate the HS mass-dimensional parameters and their characteristics are described. In the experimental part of the paper results are given of experiments on the pre-heating device aiding to start a carburettor engine under operational conditions and analysis of data received. Practical confirmation of the theoretical development of HS devices for a bus engine for starting by pre-heating is given.

  2. Investigation on full distribution CNC system based on SERCOS bus

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    A full distribution CNC system based on SERCOS bus is studied in accordance with the limitations of traditional PC-based motion card.The conventional PC-based motion control card is dispersed into several autonomous intelligent servo-control units with the function of servo driver.The autonomous intelligent servocontrol units realize the loop control of position,velocity and current.Interpolation computation is completed in PC and the computational results are transferred to every autonomous intelligent servo-control unit by high speed SERCOS bus.Software or hardware synchronization technology is used to ensure all servomotors are successive and synchronously running.The communication and synchronization technology of SERCOS are also researched and the autonomous intelligent servo-control card is developed byself.Finally,the experiment of circle contour process on a prototype system proves the feasibility.

  3. Capacity models on expressway near a bus bay stop with an access

    Institute of Scientific and Technical Information of China (English)

    张洪宾; 孙小端; 贺玉龙; 宇仁德

    2015-01-01

    To determinate the expressway capacity near a bus bay stop with an access, capacity models on the expressway near a bus stop with an access were developed on the basis of gap acceptance theory and queuing theory. Depending on a bus stop position to an entrance or an exit ramp, the capacity models were developed for four cases. Bus bay stops with overflow and bus bay stops without overflow were considered. A comparison of simulation experiment and model calculation was carried out. Results show that the suggested models have high accuracy and reliability, at bus arrival rate below 60 vehicles per hour (veh/h) or vehicle volumes at the entrance and the exit below 200 passenger cars units per hour (pcu/h), and there are no significant difference in the capacities for four cases. When bus arrival rate is above 240 veh/h, the capacities of all four cases will decline rapidly. With berth number increasing, the increasing of the capacities is no obvious for four cases. As the bus arrival rate and vehicle volumes at the entrance and the exit increase, bus stops located downstream of an entrance and upstream of an exit have a remarkably effect on the capacities. The latter case is much heavier than the former. Those results can be used to traffic design and optimization on urban expressway near a bus stop with an access.

  4. Common Traffic Violations of Bus Drivers in Urban China: An Observational Study.

    Directory of Open Access Journals (Sweden)

    Qiqi Wang

    Full Text Available To report common traffic violations in bus drivers and the factors that influence those violations in urban China.We conducted an observational study to record three types of traffic violations among bus drivers in Changsha City, China: illegal stopping at bus stations, violating traffic light signals, and distracted driving. The behaviors of bus drivers on 32 routes (20% of bus routes in the city were observed. A two-level Poisson regression examined factors that predicted bus driver violations.The incidence of illegal stopping at bus stations was 20.2%. Illegal stopping was less frequent on weekends, sunny days, and at stations with cameras, with adjusted incidence rate ratios (IRRs of 0.81, 0.65 and 0.89, respectively. The incidence of violating traffic light signals was 2.2%, and was lower on cloudy than sunny days (adjusted IRR: 0.60. The incidence of distracted driving was 3.3%. The incidence of distracted driving was less common on cloudy days, rainy or snowy days, and foggy/windy/dusty days compared to sunny days, with adjusted IRRs of 0.54, 0.55 and 0.07, respectively.Traffic violations are common in bus drivers in urban China and they are associated with the date, weather, and presence of traffic cameras at bus station. Further studies are recommended to understand the behavioral mechanisms that may explain bus driver violations and to develop feasible prevention measures.

  5. BUS BAY PERFORMANCE AND ITS INFLUENCE ON THE CAPACITY OF ROAD NETWORK IN DAR ES SALAAM

    Directory of Open Access Journals (Sweden)

    Nurdin K. Mushule

    2012-01-01

    Full Text Available One of major problems facing motorists in Dar es Salaam city today is congestion. Bus bays have a significant influence on the capacity of a roadway because they interfere with passing vehicles primarily when buses maneuver to pull into and out of bus bays. Bus bay stops will also interfere with vehicles movement if bus demand exceeds the bus bay capacity resulting in some buses waiting in the travel lane until the buses occupying the bay exit the bay. This paper presents the results of a study which was carried out to evaluate the bus bay performance and its influence on the capacity of the roadway network in the city of Dar es Salaam. The case study area covered 11 bus stops along Morogoro road from Ubungo to Magomeni Mapipa. Capacity of bus bays was studied using procedure outlined in the Transit Capacity and Quality of Service Manual of 2003. This enabled the researcher to determine parameters such as dwell times and clearance times which are major determinants of bus stop capacity. The results indicate that only 18% of the bus bay stops studied did not have adequate capacity to cater for the available demand. 9% did not have adequate capacity during peak hours but the capacity was adequate during off-peak hours. The remaining 73% of bus bay stops possess adequate capacity all the time. Although most bus bay stops studied possess adequate capacity, severe congestion was observed at these locations. This is due to erratic behavior of bus drivers who do not utilize the provided space for them to drop off and pick up passengers. Clearly, this is an area that requires more strict enforcement in order to ease the congestion problem in the city by operating the existing capacity more efficiently."

  6. System investigation H2 bus fleet (technology, regulations, future development)

    International Nuclear Information System (INIS)

    In cooperation with Ansaldo Ricerche, ICIL have compiled a technical catalogue, providing the impartial descriptions, both of existing technology and regulations, and the likely future developments of these, as to remedy the first problem faced by a potential hydrogen bus fleet operator viz the absence of an impartial description of the available vehicle and fuels systems together with the absence of a description of regulatory and safety factors which need consideration. (orig.)

  7. Modelling urban bus transport emissions in Santiago de Cuba

    OpenAIRE

    Warren, James; Avila, Jordi Mirabent

    2010-01-01

    This study described and focuses on the public transport bus system in Santiago de Cuba. Specifically we explore the fuel consumption of the various diesel buses over a three year period from 2007 to 2009 and with a forecast for the forthcoming years. The study considers the potential for fuel savings through a variety of methods which are each described and then modelled. Pollution is also calculated for a variety of scenarios and some suggestions are made in order to lower the overall...

  8. Damping torque analysis for DC bus implemented damping control

    OpenAIRE

    W. Du; WANG, HAIFENG; Ju, P.; Dunn, R

    2010-01-01

    Damping torque analysis is a well-developed technique for understanding and studying power system oscillations. This paper presents the applications of damping torque analysis for DC bus implemented damping control in power transmission networks in two examples. The first example is the investigation of damping effect of shunt VSC (Voltage Source Converter) based FACTS voltage control, i.e., STATCOM (Static Synchronous Compensator) voltage control. It is shown in the paper that STATCOM voltag...

  9. An asynchronous controller for a daisychainable vme bus interrupter

    OpenAIRE

    Wollowski, Ralf; Beister, Jochen; Kuhn, Matthias

    1999-01-01

    An interrupter for use in a daisy-chained VME bus interrupt system has beendesigned and implemented as an asynchronous sequential circuit. The concur-rency of the processes posed a design problem that was solved by means of asystematic design procedure that uses Petri nets for specifying system and in-terrupter behaviour, and for deriving a primitive flow table. Classical designand additional measures to cope with non-fundamental mode operation yieldeda coded state-machine representation. Thi...

  10. FAKTOR PENYEBAB KERUSAKAN SISTEM MESIN PADA BUS APTB PPD

    OpenAIRE

    Laela Chairani; Yulita Veranda Usman; Nur Yulianti Hidayah

    2015-01-01

    Comfort and safety of public transportation, particularly APTB PPD buses, becomes high expectations for its customers. Those expectations must be supported by the application of a good engine maintenance system. By using the method of Reliability Centered Maintenance may be determined appropriate actions to mitigate damage. From the analysis known the failures of the APTB PPD bus are malfunctions of the fuel engine, power transfer systems, difficulty to move the gear lever, and lubricating sy...

  11. Evaluation of Bus Vibration Comfort Based on Passenger Crowdsourcing Mode

    Directory of Open Access Journals (Sweden)

    Hong Zhao

    2016-01-01

    Full Text Available Vibration comfort is an important factor affecting the quality of service (QoS of bus. In order to make people involved in supervising bus’s vibration comfort and improve passengers’ riding experience, a novel mode of passenger crowdsourcing is introduced. In this paper, comfort degree of bus vibration is calculated from bus’s vibration signals collected by passengers’ smartphones and sent through WiFi to the Boa web server which shows the vibration comfort on the LCD deployed in bus and maybe trigger alarm lamp when the vibration is beyond the threshold. Three challenges here have been overcome: firstly, space coordinate transformation algorithm is used to solve the constant drift of signals collected; secondly, a low-pass filter is designed to isolate gravity from signals real-timely via limited computing resources; thirdly, an embedded evaluation system is developed according to the calculation procedure specified by criterion ISO 2631-1997. Meanwhile, the model proposed is tested in a practical running environment, the vibration data in whole travel are recorded and analyzed offline. The results show that comfort degree of vibration obtained from the experimental system is identical with the truth, and this mode is proved to be effective.

  12. Safety evaluation of a hydrogen fueled transit bus

    Energy Technology Data Exchange (ETDEWEB)

    Coutts, D.A.; Thomas, J.K.; Hovis, G.L.; Wu, T.T. [Westinghouse Savannah River Co., Aiken, SC (United States)

    1997-12-31

    Hydrogen fueled vehicle demonstration projects must satisfy management and regulator safety expectations. This is often accomplished using hazard and safety analyses. Such an analysis has been completed to evaluate the safety of the H2Fuel bus to be operated in Augusta, Georgia. The evaluation methods and criteria used reflect the Department of Energy`s graded approach for qualifying and documenting nuclear and chemical facility safety. The work focused on the storage and distribution of hydrogen as the bus motor fuel with emphases on the technical and operational aspects of using metal hydride beds to store hydrogen. The safety evaluation demonstrated that the operation of the H2Fuel bus represents a moderate risk. This is the same risk level determined for operation of conventionally powered transit buses in the United States. By the same criteria, private passenger automobile travel in the United States is considered a high risk. The evaluation also identified several design and operational modifications that resulted in improved safety, operability, and reliability. The hazard assessment methodology used in this project has widespread applicability to other innovative operations and systems, and the techniques can serve as a template for other similar projects.

  13. Perspective Application of Passive Optical Network with Optimized Bus Topology

    Directory of Open Access Journals (Sweden)

    P. Lafata

    2012-06-01

    Full Text Available Passive optical networks (PONs represent a promising solution for modern access telecommunication networks.These networks are able to meet the increasing demands on transmission rate for demanding multimedia services,while they can offer typical shared transmission speed of 1.25 or 2.5 Gbps. The major role in deploying opticaldistribution networks ODNs plays the maximum attenuable loss, which is caused mainly by passive optical splitters.This paper proposes an innovative application of passive optical networks with optimized bus topology especially forlocal backbone data networks. Due to using only passive components, it is necessary to optimize certain parameters,especially an overall attenuation balance. Considering the possibility of such optimization, the passive optical networkwith optimized bus topology provides several interesting opportunities for specific applications. This paper will presentselected aspects of passive optical networks and splitters with asymmetric splitting ratio. The essential part is focusedon the practical demonstration of their use to optimize the passive optical network with bus topology, which acts as alocal backbone network for structured cabling systems, and for local data networks in large buildings.

  14. Designing Parallel Bus Using Universal Asynchronous Receiver Transmitter

    Directory of Open Access Journals (Sweden)

    Satyandra Sharad

    2013-04-01

    Full Text Available This paper entitled “DESIGNING PARALLEL BUSUSING UNIVERSAL ASYNCHRONOUS RECEIVER TRANSMITTER” is designed to the core of a UART interface module, which includes both receive and transmit modules, and the command parser. This paper will be a viable solution to design parallel buses with the help of UART. In the test bench , there is a RFM(register file model to which we write/read back data from just to check our design .The txt file issues serial inputs to the core and the core outputs parallel data and address in the form of bus. This bus is connected to our RFM (register file model instantiated in the test bench along with the design. This makes easy to retrieve parallel data from serial input. The base of the paper is to use microcontroller along with other components to interface with the physical world. In contrast, most serial communication must first be converted back into parallel form by a universal asynchronous receiver/transmitter (UART before they may be directly connected to a data bus. Both Transmissions (Parallel and Serial are used to connect peripheral devices and enable us to communicate with these devices. The UART core described here is designed using VHDL and implemented on Xilinx Vertex FPGA.

  15. Ring Bus Architecture for a Solid-State Recorder

    Science.gov (United States)

    Walker, W. John; Kopf, Edward; Cox, Brian

    2008-01-01

    A document concisely describes a ring bus architecture for a proposed solid-state recorder (SSR) that would serve as buffer of data to be transmitted from a spacecraft to Earth. This architecture would afford fault tolerance needed for reliable operation in an anticipated high-radiation environment in which traditional SSRs cannot operate reliably. Features of the architecture include one or more controller boards and multiple memory boards interconnected in a ringlike topology. The interconnections would be high-speed serial links complying with the Institute of Electrical and Electronics Engineers (IEEE) standard 1393 (which pertains to a spaceborne fiber-optic data bus). Accordingly, each controller and memory board would be equipped with an IEEE-1393-compliant ring-bus-interface unit. The ringlike topology and the multiplicity of memory boards (and, optionally, of controller boards) would afford the redundancy needed for fault tolerance. Each board would be a fault-containment region. The IEEE 1393 links could be routed so that the SSR would continue to function even in the event of multiple failures. This architecture would also support scalability over a wide range. In a fully redundant configuration, it could accommodate between 1 and 125 memory boards.

  16. The Data Acquisition System Based on PMC Bus

    CERN Document Server

    Igarashi, Y; Higuchi, T; Ikeno, M; Inoue, E; Itoh, R; Kodama, H; Murakami, T; Nagasaka, Y; Nakao, M; Nakayoshi, K; Saitoh, M; Shimazaki, S; Suzuki, S Y; Tanaka, M; Tauchi, K; Varner, G; Yamauchi, M; Yasu, Y; Katayama, T; Watanabe, K; Ishizuka, M; Onozawa, S

    2003-01-01

    High energy physics experiments in KEK/Japan rush into over KHz trigger stage. Thus, we need a successor of the data acquisition(DAQ) system that replaces the CAMAC or FASTBUS systems. To meet these needs, we have developed a DAQ system which includes a crate, base-board modules, daughter cards for front-end A/D or T/D conversion, and back-end communication cards for data transfer and timing control. The size of the crate is for the 9U Euro-cards with the standard VME32 bus and extension connectors for power supply. The base-board comprises of a local bus with the sequencer connected to the front-end daughter cards via event buffering FIFOs, and the standard PMC (PCI mezzanine card) bus to be set a PMC processor unit to reduce data size from the front-end daughter cards. A data transfer module, which is connected to the event building system, and a trigger control unit, which communicates with the central timing controller are installed on the back-end communication card connected to the rear end of the base-...

  17. Prodigiosin inhibits motility and activates bacterial cell death revealing molecular biomarkers of programmed cell death.

    Science.gov (United States)

    Darshan, N; Manonmani, H K

    2016-12-01

    The antimicrobial activity of prodigiosin from Serratia nematodiphila darsh1, a bacterial pigment was tested against few food borne bacterial pathogens Bacillus cereus, Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli. The mode of action of prodigiosin was studied. Prodigiosin induced bactericidal activity indicating a stereotypical set of biochemical and morphological feature of Programmed cell death (PCD). PCD involves DNA fragmentation, generation of ROS, and expression of a protein with caspase-like substrate specificity in bacterial cells. Prodigiosin was observed to be internalized into bacterial cells and was localized predominantly in the membrane and the nuclear fraction, thus, facilitating intracellular trafficking and then binding of prodigiosin to the bacterial DNA. Corresponding to an increasing concentration of prodigiosin, the level of certain proteases were observed to increase in bacteria studied, thus initiating the onset of PCD. Prodigiosin at a sub-inhibitory concentration inhibits motility of pathogens. Our observations indicated that prodigiosin could be a promising antibacterial agent and could be used in the prevention of bacterial infections. PMID:27460563

  18. Interplay between autophagy and programmed cell death in mammalian neural stem cells

    Directory of Open Access Journals (Sweden)

    Kyung Min Chung

    2013-08-01

    Full Text Available Mammalian neural stem cells (NSCs are of particular interestbecause of their role in brain development and function. Recentfindings suggest the intimate involvement of programmed celldeath (PCD in the turnover of NSCs. However, the underlyingmechanisms of PCD are largely unknown. Although apoptosis isthe best-defined form of PCD, accumulating evidence hasrevealed a wide spectrum of PCD encompassing apoptosis,autophagic cell death (ACD and necrosis. This mini-reviewaims to illustrate a unique regulation of PCD in NSCs. Theresults of our recent studies on autophagic death of adulthippocampal neural stem (HCN cells are also discussed. HCNcell death following insulin withdrawal clearly provides areliable model that can be used to analyze the molecularmechanisms of ACD in the larger context of PCD. Moreresearch efforts are needed to increase our understanding of themolecular basis of NSC turnover under degenerating conditions,such as aging, stress and neurological diseases. Efforts aimed atprotecting and harnessing endogenous NSCs will offer novelopportunities for the development of new therapeutic strategiesfor neuropathologies. [BMB Reports 2013; 46(8: 383-390

  19. Salt Stress-induced Programmed Cell Death in Rice Root Tip Cells

    Institute of Scientific and Technical Information of China (English)

    Jian-You Li; Ai-Liang Jiang; Wei Zhang

    2007-01-01

    Salt stressed rice root tips were used to investigate the changes of reactive oxygen species (ROS) and antioxidant enzymes at the early stages of programmed cell death (PCD). The results indicated that 500 mmol/L NaCl treatment could lead to specific features of PCD in root tips, such as DNA ladder, nuclear condense and deformation, and transferase mediated dUTP nick end labeling positive reaction, which were initiated at 4 h of treatment and progressed thereafter. Cytochrome c release from mitochondria into cytoplasm was also observed, which occurred at 2 h and was earlier than the above nuclear events. In the very early phase of PCD, an immediate burst in hydrogen peroxide and superoxide anion production rate was accompanied by two-phase changes of superoxide dismutases and ascorbate peroxidase. A short period of increase in the activity was followed by prolonged impairment. Thus,we conclude that salt can induce PCD in rice root tip cells, and propose that in the early phase of rice root tip cell PCD, salt stress-induced oxidative burst increased the antioxidant enzyme activity, which, In turn, scavenged the ROS and abrogated PCD. Also, when the stress is prolonged, the antioxidant system is damaged and accumulated ROS induces the PCD process, which leads to cytochrome c release and nuclear change.

  20. Global system data bus using the Digital Autonomous Terminal Access Communication protocol

    Science.gov (United States)

    Holmes, David C. E.

    1986-01-01

    Modern digital avionic systems with distributed processing require networking to connect the many elements. Digital Autonomous Terminal Access Communication (DATAC) is one of many such networks. DATAC has been implemented on the Transport Systems Research Vehicle (TSRV), a Boeing 737 aircraft operated by the National Aeronautics and Space Administration's Advanced Transport Operating Systems Program Office (ATOPS). This paper presents the TSRV implementation of the DATAC bus, a description of the DATAC system, a synchronization mechanism, details of data flow throughout the system, and a discussion of the modes available with DATAC. Numerous flight tests have been conducted using DATAC as the only means of communication between systems with outstanding results. DATAC is now an integral part of the TSRV and is expected to satisfy near term as well as future requirements for growth and flexibility.

  1. Le temps des conductrices de bus The time of female bus drivers. For some thinking space between professional and personal activities

    Directory of Open Access Journals (Sweden)

    Livia Scheller

    2009-11-01

    Full Text Available Nous présentons une réflexion sur les liens entre temps de travail et temps de l’espace privé, issue d’une étude faite avec des conductrices de bus.  Pour elles, comme pour la plupart des femmes, le temps de travail et le temps dit « hors travail » sont difficilement dissociables. Si la séparation entre sphères d’activité est, pour les hommes et pour les femmes, une dimension psychiquement recherchée, chez les femmes elle n’implique pas des clivages constitutifs. Elles savent bien que l’activité de travail offre des occasions de développement d’une autre origine que celles déployées dans d’autres espaces de vie. Mais à la différence des hommes, elles n’ont pas fait de cette séparation un repère identitaire. Nous avançons que la capacité de différencier, d’une part, ces genres d’activité, et, d’autre part, la possibilité de les investir « normativement », peut être une source de santé. Comment ? En créant les modes de séparation nécessaires à cette différenciation, sans pour autant perdre la perméabilité entre les deux espaces. Il s’agit de penser une position qui, bien qu’apparemment contradictoire, ne l’est pas. On pourra en trouver une illustration dans l’expérience des conductrices de bus.Taking off from a study we carried out with woman bus drivers, we analyze how working time and private time relate to each other. For them, as for most women, time at work and time off work cannot be completely separated. While psychologically the separation between different spheres of activity is something to which both men and women aspire, women do not actually demand it. They seem to know that the possibilities afforded by work are of a different nature than those of other sorts of activity. However, unlike men, women have not made that distinction a point of reference in their self-identity. We argue that the ability to distinguish the types of activity on the one hand, and on the

  2. Bitmap-Wise Wireless M-Bus Coordination for Sustainable Real Time Energy Management

    Directory of Open Access Journals (Sweden)

    Kwang-il Hwang

    2014-07-01

    Full Text Available Even though WM-Bus is being considered to be the most promising network protocol for smart metering, it is not suitable for a sustainable real-time home energy management system (HEMS, which requires higher reliability and longer lifetime despite real time bi-directional communications. Therefore, in this paper we propose a Bitmap-wise WM-Bus (BWM-Bus, coping well with sustainable real-time HEMS. In particular, the proposed scheme addresses the several problems in WM-Bus for HEMS by introducing novel functions: asynchronous meter trigger, adaptive slot scheduling, and bitmap-wise retransmission request. Through experiments, we demonstrate that BWM-Bus guarantees higher data success ratio with lower data aggregation time, as well as longer lifetime than WM-Bus standard.

  3. Identification of voltage stability condition of a power system using measurements of bus variables

    Directory of Open Access Journals (Sweden)

    Durlav Hazarika

    2014-12-01

    Full Text Available Several online methods were proposed for investigating the voltage stability condition of an interconnected power system using the measurements of voltage and current phasors at a bus. For this purpose, phasor measurement units (PMUs are used. A PMU is a device which measures the electrical waves on an electrical network, using a common time source (reference bus for synchronisation. This study proposes a method for online monitoring of voltage stability condition of a power system using measurements of bus variables namely – (i real power, (ii reactive power and (iii bus voltage magnitude at a bus. The measurements of real power, reactive power and bus voltage magnitude could be extracted/captured from a smart energy meter. The financial involvement for implementation of the proposed method would significantly lower compared with the PMU-based method.

  4. Design and VHDL simulation of a special high speed spaceborne bus controller

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    The application of high speed data bus on the satellites having several remote sensors could not only satisfy the demand of high speed data transfer,but also could reuse the equipment at both the com-ponent and subsystem levels for other space missions,thus reducing the costs of on-board processing system integration.In this article,a special high speed data bus with simple interfaces is chosen for transferring the data produced by remote sensors and other instrumentations.First,the function and the structure of the data bus are discussed carefully.And then,the bus controller,which is a key mod-ule of the data bus,is designed.At last,the function and performance of the bus controller are verified by VHDL simulation.

  5. Involvement of ethylene and lipid signalling in cadmium-induced programmed cell death in tomato suspension cells.

    Science.gov (United States)

    Yakimova, E T; Kapchina-Toteva, V M; Laarhoven, L-J; Harren, F M; Woltering, E J

    2006-10-01

    Cadmium-induced cell death was studied in suspension-cultured tomato (Lycopersicon esculentum Mill.) cells (line MsK8) treated with CdSO(4). Within 24 h, cadmium treatment induced cell death in a concentration-dependent manner. Cell cultures showed recovery after 2-3 days which indicates the existence of an adaptation mechanism. Cadmium-induced cell death was alleviated by the addition of sub muM concentrations of peptide inhibitors specific to human caspases indicating that cell death proceeds through a mechanism with similarities to animal programmed cell death (PCD, apoptosis). Cadmium-induced cell death was accompanied by an increased production of hydrogen peroxide (H(2)O(2)) and simultaneous addition of antioxidants greatly reduced cell death. Inhibitors of phospholipase C (PLC) and phospholipase D (PLD) signalling pathway intermediates reduced cadmium-induced cell death. Treatment with the G-protein activator mastoparan and a cell permeable analogue of the lipid signal second messenger phosphatidic acid (PA) induced cell death. Ethylene, while not inducing cell death when applied alone, stimulated cadmium-induced cell death. Application of the ethylene biosynthesis inhibitor aminoethoxy vinylglycine (AVG) reduced cadmium-induced cell death, and this effect was alleviated by simultaneous treatment with ethylene. Together the results show that cadmium induces PCD exhibiting apoptotic-like features. The cell death process requires increased H(2)O(2) production and activation of PLC, PLD and ethylene signalling pathways.

  6. Differential programming of B cells in AID deficient mice.

    Directory of Open Access Journals (Sweden)

    Marc A Hogenbirk

    Full Text Available The Aicda locus encodes the activation induced cytidine deaminase (AID and is highly expressed in germinal center (GC B cells to initiate somatic hypermutation (SHM and class switch recombination (CSR of immunoglobulin (Ig genes. Besides these Ig specific activities in B cells, AID has been implicated in active DNA demethylation in non-B cell systems. We here determined a potential role of AID as an epigenetic eraser and transcriptional regulator in B cells. RNA-Seq on different B cell subsets revealed that Aicda(-/- B cells are developmentally affected. However as shown by RNA-Seq, MethylCap-Seq, and SNP analysis these transcriptome alterations may not relate to AID, but alternatively to a CBA mouse strain derived region around the targeted Aicda locus. These unexpected confounding parameters provide alternative, AID-independent interpretations on genotype-phenotype correlations previously reported in numerous studies on AID using the Aicda(-/- mouse strain.

  7. Case Study - Propane School Bus Fleets

    Energy Technology Data Exchange (ETDEWEB)

    Laughlin, M; Burnham, A.

    2014-08-31

    As part of the U.S. Department of Energy’s (DOE’s) effort to deploy transportation technologies that reduce U.S. dependence on imported petroleum, this study examines five school districts, one in Virginia and four in Texas, successful use of propane school buses. These school districts used school buses equipped with the newly developed liquid propane injection system that improves vehicle performance. Some of the school districts in this study saved nearly 50% on a cost per mile basis for fuel and maintenance relative to diesel. Using Argonne National Laboratory’s Alternative Fuel Life-Cycle Environmental and Economic Transportation (AFLEET) Tool developed for the DOE’s Clean Cities program to help Clean Cities stakeholders estimate petroleum use, greenhouse gas (GHG) emissions, air pollutant emissions and cost of ownership of light-duty and heavy-duty vehicles, the results showed payback period ranges from 3—8 years, recouping the incremental cost of the vehicles and infrastructure. Overall, fuel economy for these propane vehicles is close to that of displaced diesel vehicles, on an energy-equivalent basis. In addition, the 110 propane buses examined demonstrated petroleum displacement, 212,000 diesel gallon equivalents per year, and GHG benefits of 770 tons per year.

  8. DoD Climate Change Fuel Cell Program

    Energy Technology Data Exchange (ETDEWEB)

    Steven A. Gabrielle

    2007-04-30

    A grant was awarded to PPL EnergyPlus, LLC for two (2) 250kW Molten Carbonate Fuel Cells at Pepperidge Farm, Inc. on 9/30/03. Pepperidge Farm subsequently signed a contract for one 250kW fuel cell. A request was made and granted to apply the award for the second fuel cell to the Sheraton New York Hotel & Towers (see attached email). This report discusses the first year of operation of a fuel cell power plant located at Pepperidge Farm, Inc., Bloomfield, Connecticut and a fuel cell power plant located at Sheraton New York Hotel & Towers, New York, New York. PPL EnergyPlus, LLC installed the plants under a contract with Pepperidge Farm and Starwood Hotels & Resorts Worldwide, Inc. Two DFC 300 fuel cells, manufactured by FuelCell Energy, Inc. of Danbury, CT were selected for the project. The fuel cell located at Pepperidge Farm successfully operated from January 16, 2006 to January 15, 2007. The fuel cell located at Sheraton New York Hotel & Tower successfully operated from May 19, 2005 to May 18, 2006.This report discusses the performance of these plants during these periods.

  9. Best Operational and Maintenance Practices for City Bus Fleets to Maximize Fuel Economy

    OpenAIRE

    World Bank

    2011-01-01

    In most large cities in developing countries, buses continue to be the public transport option of choice, carrying a large share of urban travelers. However, transit bus companies in these countries are often cash-strapped. In many cases, the operating cost per bus kilometer exceeds revenues and bus fares are often kept low irrespective of the cost of providing service. Many cities are dom...

  10. Reducing carbon emissions by introducing electric vehicle enhanced dedicated bus lanes

    OpenAIRE

    Doolan, Ronan; Muntean, Gabriel-Miro

    2014-01-01

    Most cities have special lanes dedicated to buses, however these lanes are rarely used at full capacity. At the same time governments around the world are encouraging people to buy electric vehicles. This paper proposes the creation of electric vehicle enhanced dedicated bus lanes (E-DBL), by allowing electric vehicles access to bus lanes, in order to improve the use of road capacity. By opening bus lanes to electric vehicles, traffic congestion could be eased, the range ...

  11. The impact of bus drivers ’ lifestyle on the occurrence of health problems and absenteeism

    OpenAIRE

    Andrej Jerman; Maja Meško

    2016-01-01

    Research Question: Do bus drivers’ lifestyles affect the occurrence of health problems and absenteeism? Purpose: The purpose of the study was to determine whether the lifestyle of professional bus drivers affects the occurrence of health problems and the phenomenon of absenteeism. Method: A quantitative research method was used in the research. Data were collected using a structured questionnaire, on a sample of 230 professional bus drivers from differ...

  12. The Bus Extension Module Design and Verification of POSAFE-Q Using LVDS

    International Nuclear Information System (INIS)

    This paper described the Bus Extension Module using Low Voltage Differential Signal (LVDS). A Bus Extension Module use Safety-Related PLC (Programmable Logic Controller), called POSAFE-Q (made by POSCO ICT), for handling many data (I/O) extension rack. A processor module of POSAFE-Q can control I/O Module installed another rack. This paper explains Bus Extension Module and Data transfer technology using LVDS. (author)

  13. Introduction to corridor selection & assessment for Bus Rapid Transit System (BRTS) in Hyderabad

    OpenAIRE

    Bhanu Kireeti Chanda; Maddali Sai Satya Goutham

    2014-01-01

    Bus rapid transit system is an innovation and it is up gradation to the present transport system. BRT is affordable, adaptable and cost effective. The term of rapid transit system means a form of high speed urban passenger transportation. Here, the mode of transportation is bus hence it is called as bus rapid transit system (BRTS). Transportation facilities and the system will be different form different countries. Especially for the developing countries, transportation is a problem and BR...

  14. The influence of bus stop on traffic flow with velocity-difference-separation model

    Science.gov (United States)

    Zheng, Pengjun; Wang, Wei; Ge, Hongxia

    2016-06-01

    Based on velocity-difference-separation model, the mixed traffic flow on two-lane road is investigated. For a fixed road length, the influence of bus and bus stops on traffic flow is studied with the increasing traffic density. Compared with the result without bus stops given by Li et al., a new traffic state is found, which is valuable for studying the impacts of public transport on urban traffic flow.

  15. A gibberellin-induced nuclease is localized in the nucleus of wheat aleurone cells undergoing programmed cell death

    OpenAIRE

    Domínguez, Fernándo; Moreno Onorato, Francisco Javier; Cejudo Fernández, Francisco Javier

    2003-01-01

    The aleurone layer of cereal grains undergoes a gibberellin-regulated process of programmed cell death (PCD) following germination. We have applied a combination of ultrastructural and biochemical approaches to analyze aleurone PCD in intact wheat grains. The terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling assay revealed that PCD was initiated in aleurone cells proximal to the embryo and then extended to distal cells. DNA fragmentation and terminal deoxynucleotidyl trans...

  16. Design of virtual manufacturing cells : a mathematical programming approach

    NARCIS (Netherlands)

    Slomp, J.; Chowdary, B.V.; Suresh, N.

    2005-01-01

    In this paper, a new type of virtual cellular manufacturing (CM) system is considered, and a multi-objective design procedure is developed for designing such cells in real time. Retaining the functional layout, virtual cells are addressed as temporary groupings of machines, jobs and workers to reali

  17. Tetracycline regulator expression alters the transcriptional program of mammalian cells

    OpenAIRE

    Hackl, Hubert; Rommer, Anna; Konrad, Torsten A; Nassimbeni, Christine; Wieser, Rotraud

    2010-01-01

    Tetracycline regulated ectopic gene expression is a widely used tool to study gene function. However, the tetracycline regulator (tetR) itself has been reported to cause certain phenotypic changes in mammalian cells. We, therefore, asked whether human myeloid U937 cells expressing the tetR in an autoregulated manner would exhibit alterations in gene expression upon removal of tetracycline.

  18. A Prediction System Using a P2P Overlay Network for a Bus Arrival System

    Directory of Open Access Journals (Sweden)

    Ssu-Hsuan Lu

    2014-01-01

    Full Text Available Along with the evolution of times and the surge of metropolitan populations, government agencies often promote the construction of public transport. Unlike rail transportation or rapid transit systems, it is often difficult to estimate the vehicle arrival times at each station in a bus transportation system due to metropolitan transportation congestion. Traffic status is often monitored using wireless sensor networks (WSNs. However, WSNs are always separated from one another spatially. Recent studies have considered the connection of multiple sensor networks. This study considers a combination view of peer-to-peer (P2P overlay networks and WSN architecture to predict bus arrival times. Each bus station, which is also a P2P overlay peer, is connected in a P2P overlay network. A sensor installed in each bus can receive data via peers to obtain the moving speed of a bus. Then, each peer can exchange its data to predict bus arrival times at bus stations. This method can considerably increase the accuracy with which bus arrival times can be predicted and can provide traffic status with high precision. Furthermore, these data can also be used to plan new bus routes according to the information gathered.

  19. Bitmap-Wise Wireless M-Bus Coordination for Sustainable Real Time Energy Management

    OpenAIRE

    Kwang-il Hwang; Sung-wook Nam

    2014-01-01

    Even though WM-Bus is being considered to be the most promising network protocol for smart metering, it is not suitable for a sustainable real-time home energy management system (HEMS), which requires higher reliability and longer lifetime despite real time bi-directional communications. Therefore, in this paper we propose a Bitmap-wise WM-Bus (BWM-Bus), coping well with sustainable real-time HEMS. In particular, the proposed scheme addresses the several problems in WM-Bus for HEMS by introdu...

  20. An interactive wireless communication system for visually impaired people using city bus transport.

    Science.gov (United States)

    Wang, Hsiao-Lan; Chen, Ya-Ping; Rau, Chi-Lun; Yu, Chung-Huang

    2014-05-01

    Visually impaired people have difficulty accessing information about public transportation systems. Several systems have been developed for assisting visually impaired and blind people to use the city bus. Most systems provide only one-way communication and require high-cost and complex equipment. The purpose of this study is to reduce the difficulties faced by visually impaired people when taking city buses, using an interactive wireless communication system. The system comprised a user module and a bus module to establish a direct one-to-one connection. When the user inputs 4-digit numbers, the user module immediately sends out the information. If the bus module receives the matched bus number, it buzzes and the warning LED flashes to notify the bus driver that someone is waiting to board on the bus. User tests were conducted by two visually impaired people in a simulated vehicle and a city bus. The success rate of interactive wireless communication, recognizing the arrival of the bus and boarding the correct bus reached 100% in all of the tests. The interactive wireless communication aid system is a valid and low-cost device for assisting visually impaired people to use city buses.

  1. 76 FR 68813 - FY 2011 Discretionary Livability Funding Opportunity; Section 5309 Bus and Bus Facilities...

    Science.gov (United States)

    2011-11-07

    ... companies engaged in public transportation, or private non-profit organizations. The Alternatives Analysis program makes funds available to States, authorities of States, metropolitan planning organizations, and... program, contact Kenneth Cervenka, Office of Planning and Environment, at (202) 493-0512, email:...

  2. Reversal of an immunity associated plant cell death program by the growth regulator auxin

    Directory of Open Access Journals (Sweden)

    Gopalan Suresh

    2008-12-01

    Full Text Available Abstract Background One form of plant immunity against pathogens involves a rapid host programmed cell death at the site of infection accompanied by the activation of local and systemic resistance to pathogens, termed the hypersensitive response (HR. In this work it was tested (i if the plant growth regulator auxin can inhibit the cell death elicited by a purified proteinaceous HR elicitor, (ii how far down the process this inhibition can be achieved, and (iii if the inhibition affects reporters of immune response. The effect of constitutive modulation of endogenous auxin levels in transgenic plants on this cell death program was also evaluated. Results The HR programmed cell death initiated by a bacterial type III secretion system dependent proteinaceous elicitor harpin (from Erwinia amylovora can be reversed till very late in the process by the plant growth regulator auxin. Early inhibition or late reversal of this cell death program does not affect marker genes correlated with local and systemic resistance. Transgenic plants constitutively modulated in endogenous levels of auxin are not affected in ability or timing of cell death initiated by harpin. Conclusion These data indicate that the cell death program initiated by harpin can be reversed till late in the process without effect on markers strongly correlated with local and systemic immunity. The constitutive modulation of endogenous auxin does not affect equivalent signaling processes affecting cell death or buffers these signals. The concept and its further study has utility in choosing better strategies for treating mammalian and agricultural diseases.

  3. The hydrogen and the fuel cells in the world. Programs and evolutions

    International Nuclear Information System (INIS)

    HyPac is a french platform on the hydrogen and fuel cells, created in 2008. The author presents the opportunity of such a platform facing the world research programs and other existing platforms. (A.L.B.)

  4. Programmed cell death activated by Rose Bengal in Arabidopsis thaliana cell suspension cultures requires functional chloroplasts.

    Science.gov (United States)

    Gutiérrez, Jorge; González-Pérez, Sergio; García-García, Francisco; Daly, Cara T; Lorenzo, Oscar; Revuelta, José L; McCabe, Paul F; Arellano, Juan B

    2014-07-01

    Light-grown Arabidopsis thaliana cell suspension culture (ACSC) were subjected to mild photooxidative damage with Rose Bengal (RB) with the aim of gaining a better understanding of singlet oxygen-mediated defence responses in plants. Additionally, ACSC were treated with H2O2 at concentrations that induced comparable levels of protein oxidation damage. Under low to medium light conditions, both RB and H2O2 treatments activated transcriptional defence responses and inhibited photosynthetic activity, but they differed in that programmed cell death (PCD) was only observed in cells treated with RB. When dark-grown ACSC were subjected to RB in the light, PCD was suppressed, indicating that the singlet oxygen-mediated signalling pathway in ACSC requires functional chloroplasts. Analysis of up-regulated transcripts in light-grown ACSC, treated with RB in the light, showed that both singlet oxygen-responsive transcripts and transcripts with a key role in hormone-activated PCD (i.e. ethylene and jasmonic acid) were present. A co-regulation analysis proved that ACSC treated with RB exhibited higher correlation with the conditional fluorescence (flu) mutant than with other singlet oxygen-producing mutants or wild-type plants subjected to high light. However, there was no evidence for the up-regulation of EDS1, suggesting that activation of PCD was not associated with the EXECUTER- and EDS1-dependent signalling pathway described in the flu mutant. Indigo Carmine and Methylene Violet, two photosensitizers unable to enter chloroplasts, did not activate transcriptional defence responses in ACSC; however, whether this was due to their location or to their inherently low singlet oxygen quantum efficiencies was not determined.

  5. Combinatorial Optimization Model of Bus Stop in BRT Station-group%BRT车站组的线路停靠组合优化模型

    Institute of Scientific and Technical Information of China (English)

    林培群; 徐建闽

    2011-01-01

    In order to relieve the problem that queuing for bus stop in the single-lane of bus rapid transit (BRT) station occurs frequently, a combinatorial optimization model of bus stop in BRT station-group was put forward. Firstly, the non-queuing probability model for a single-lane of BRT station was deduced based on queuing theory. Then, a mixed integer programming model of minimizing the queuing probability of bus stop in station-group was proposed. Furthermore, a global-optimal solution algorithm on the basis of distributed parallel-search, and a local-optimal solution algorithm on the basis of greedy strategy were proposed to solve the combinatorial optimization model. Finally, the optimal bus stop program of a typical BRT station-group in Guangzhou was obtained by the proposed method in the example. Using VISSIM software, the optimal program and existing program were simulated. Results show that the proposed method can relieve the queuing situation of bus stop in station effectively.%为了缓解公交车辆进入单车道快速公交(BRT)车站容易出现排队的问题,提出了BRT车站组的线路停靠组合优化模型.首先基于排队论推导出BRT车辆进站不发生排队的概率模型,然后以最小排队概率为目标,提出整个车站组的线路停靠混合整数规划模型,并针对该模型的求解分别给出了一种基于分布式并行搜索的全局最优解算法和一种基于贪心策略的次优解快速算法;最后通过算例计算出广州市某个典型BRT车站组的线路停靠最优方案,利用VISSIM软件对优化方案及现有方案进行了多次仿真.结果表明:所提出的方法能够有效缓解公交车辆的进站排队现象.

  6. A novel approach for studying programmed cell death in living plant tissues

    DEFF Research Database (Denmark)

    Mark, Christina

    insight by determining both the intra- and extracellular reducing capacity in living cells rather than using cell extracts. The reducing capacity of aleurone cells was shown to increase over time in parallel with the increase in cell death. Use of the flavoenzyme inhibitor diphenyleneiodonium chloride......, and enabled a higher throughput. The system wasused for parallel time course studies of cell viability, intracellular reducing capacity and transient expression profiles in immobilised tissue under multiple incubation conditions. Immobilisation resulted in decreased rates of cell death due to the lower......Programmed cell death (PCD) is a highly regulated process in which cells are killed as part of developmental programmes or as defence mechanisms against pathogens, but the process is less well understood in plant cells compared to animal cells. Reactive oxygen species (ROS) are involved in PCD...

  7. Characterization of the replication timing program of 6 human model cell lines.

    Science.gov (United States)

    Hadjadj, Djihad; Denecker, Thomas; Maric, Chrystelle; Fauchereau, Fabien; Baldacci, Giuseppe; Cadoret, Jean-Charles

    2016-09-01

    During the S-phase, the DNA replication process is finely orchestrated and regulated by two programs: the spatial program that determines where replication will start in the genome (Cadoret et al. (2008 Oct 14), Cayrou et al. (2011 Sep), Picard et al. (2014 May 1) [1], [2], [3]), and the temporal program that determines when during the S phase different parts of the genome are replicated and when origins are activated. The temporal program is so well conserved for each cell type from independent individuals [4] that it is possible to identify a cell type from an unknown sample just by determining its replication timing program. Moreover, replicative domains are strongly correlated with the partition of the genome into topological domains (determined by the Hi-C method, Lieberman-Aiden et al. (2009 Oct 9), Pope et al. (2014 Nov 20) [5], [6]). On the one hand, replicative areas are well defined and participate in shaping the spatial organization of the genome for a given cell type. On the other hand, studies on the timing program during cell differentiation showed a certain plasticity of this program according to the stage of cell differentiation Hiratani et al. (2008 Oct 7, 2010 Feb) [7], [8]. Domains where a replication timing change was observed went through a nuclear re-localization. Thus the temporal program of replication can be considered as an epigenetic mark Hiratani and Gilbert (2009 Feb 16) [9]. We present the genomic data of replication timing in 6 human model cell lines: U2OS (GSM2111308), RKO (GSM2111309), HEK 293T (GSM2111310), HeLa (GSM2111311), MRC5-SV (GSM2111312) and K562 (GSM2111313). A short comparative analysis was performed that allowed us to define regions common to the 6 cell lines. These replication timing data can be taken into account when performing studies that use these model cell lines. PMID:27508120

  8. Characterization of the replication timing program of 6 human model cell lines

    Directory of Open Access Journals (Sweden)

    Djihad Hadjadj

    2016-09-01

    Full Text Available During the S-phase, the DNA replication process is finely orchestrated and regulated by two programs: the spatial program that determines where replication will start in the genome (Cadoret et al. (2008 Oct 14, Cayrou et al. (2011 Sep, Picard et al. (2014 May 1 [1–3], and the temporal program that determines when during the S phase different parts of the genome are replicated and when origins are activated. The temporal program is so well conserved for each cell type from independent individuals [4] that it is possible to identify a cell type from an unknown sample just by determining its replication timing program. Moreover, replicative domains are strongly correlated with the partition of the genome into topological domains (determined by the Hi-C method, Lieberman-Aiden et al. (2009 Oct 9, Pope et al. (2014 Nov 20 [5,6]. On the one hand, replicative areas are well defined and participate in shaping the spatial organization of the genome for a given cell type. On the other hand, studies on the timing program during cell differentiation showed a certain plasticity of this program according to the stage of cell differentiation Hiratani et al. (2008 Oct 7, 2010 Feb [7,8]. Domains where a replication timing change was observed went through a nuclear re-localization. Thus the temporal program of replication can be considered as an epigenetic mark Hiratani and Gilbert (2009 Feb 16 [9]. We present the genomic data of replication timing in 6 human model cell lines: U2OS (GSM2111308, RKO (GSM2111309, HEK 293T (GSM2111310, HeLa (GSM2111311, MRC5-SV (GSM2111312 and K562 (GSM2111313. A short comparative analysis was performed that allowed us to define regions common to the 6 cell lines. These replication timing data can be taken into account when performing studies that use these model cell lines.

  9. 3He Neutron Spin Filter cell development program at JCNS

    International Nuclear Information System (INIS)

    In order to produce high-quality 3He Neutron Spin Filters (NSF) with a high polarisation level, it is necessary to achieve a long 3He relaxation time by the reduction of the wall relaxation. This requires one to minimise the amount of impurities at the surface of the glass cells, and to have as few contaminants as possible in the gas filling system. In this report we describe the detailed procedure we employ to produce 3He cells using our newly built filling station. The obtained life times for a number of cells are practically approaching the fundamental limit imposed by the dipole-dipole interaction between 3He atoms.

  10. Induction of multiple programmed cell death pathways by IFN-beta in human non-small-cell lung cancer cell lines.

    Science.gov (United States)

    Zhang, H; Koty, P P; Mayotte, J; Levitt, M L

    1999-02-25

    Tissue transglutaminase (tTG) and keratinocyte transglutaminase (kTG), as well as the cross-linked envelopes (CLE) that they form, have been associated with squamous differentiation and programmed cell death in epithelial cells. When interferon-beta (IFN-beta) was used to stimulate differentiation and programmed cell death in the human lung cancer cell lines NCI-H596 and NCI-H226, the cells underwent a decrease in cellular density. In NCI-H596 IFN-beta caused an increase in kTG activity and DNA fragmentation in the lower density cells, which were significantly slower growing than control cells. However, in the higher density cells, which were only slightly slower growing than control cells, IFN-beta caused an increase in tTG activity and CLE competence. Dual-parameter flow cytometry demonstrated that IFN-beta-induced squamous differentiation preceded programmed cell death. Treatment of NCI-H596 cells with monodansylcadaverine, a transglutaminase inhibitor, prevented the increase in CLE competence, but did not inhibit DNA fragmentation. These results suggest that IFN-beta can induce NCI-H596 cells to enter multiple cell death pathways and that these pathways are not only differentiation related, but may also be growth driven. PMID:10047455

  11. Pathways to Commercial Success. Technologies and Products Supported by the Fuel Cell Technologies Program

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2011-09-01

    This FY 2011 report updates the results of an effort to identify and characterize commercial and near-commercial (emerging) technologies and products that benefited from the support of the Fuel Cell Technologies Program and its predecessor programs within DOE's Office of Energy Efficiency and Renewable Energy.

  12. Pathways to Commercial Success. Technologies and Products Supported by the Fuel Cell Technologies Program - 2012

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2012-09-01

    This FY 2012 report updates the results of an effort to identify and characterize commercial and near-commercial (emerging) technologies and products that benefited from the support of the Fuel Cell Technologies Program and its predecessor programs within DOE's Office of Energy Efficiency and Renewable Energy.

  13. On the Design and Implementation of LIN -bus Data Monitor%汽车LIN总线数据监视器的设计与实现

    Institute of Scientific and Technical Information of China (English)

    沈万松

    2012-01-01

    LIN(Local Interconnect Network)总线是一种在汽车电子控制系统中已被普遍采用的低速、低成本的串行通讯网络。为了对基于LIN总线的分布式电子系统进行LIN总线信号测试和数据分析,对ELM633芯片的硬件电路进行设计,运用VC++软件编制实用软件,开发了操作简便的汽车LIN总线数据监视设备,由此可以成功实现对车辆LIN总线上全部信号的捕捉和采集。它的使用对LIN总线信号测试、数据分析和相关教学培训等工作具有一定的应用价值。%LIN ( Local Interconnect Network ) bus is a low - speed, low - cost serial communication network which has been widely used in automobile electronic control system. In order to test and analyze the signal that is based on LIN bus distributed electronic systems, the author has developed easy - operated automotive LIN bus data monitoring equipment by the designing of ELM633 chip hardware circuit and the programming of applying software via using VC + + software, so the capture and collection of LIN bus signal can be successfully a- chieved, which has highly valuable application in LIN bus signal testing, data analysis and related teaching and training work.

  14. Fuel options for public bus fleets in Sweden

    OpenAIRE

    Xylia, Maria; Silveira, Semida

    2015-01-01

    The Swedish public transport sector has defined two major targets, i.e., to run 90% of the total vehicle kilometers of the fleet on non-fossil fuels and double the volume of travel via public transport by 2020, increasing the share of public transport in relation to the total personal transport in the country . The f3 report Fuel options for public bus fleets in Sweden highlights the challenges and solutions encountered, particularly when it comes to the adoption of renewable fuels in the reg...

  15. Communication Architecture Synthesis for Multi-bus SoC

    Directory of Open Access Journals (Sweden)

    Abdelkrim Zitouni

    2006-01-01

    Full Text Available In the systems on chip (SoC design, the synthesis of communication architecture constitutes the bottleneck which can affect the performances of the system. Various schemes and protocols can be necessary, just as various topologies of interconnection. To reduce the complexity of the communications refinement, we present in this study a model and a synthesis approach for multi-bus communication architecture containing centralized bridge. The automation of the arbiter synthesis step profited from a detailed attention. This stage generates a hierarchical arbiter integrating various priority arbitration modules. The proposed approach was integrated in a toolbox based environment

  16. Energy model of network-on-chip and a bus

    OpenAIRE

    Wolkotte, Pascal T.; Smit, Gerard J.M.; Kavaldjiev, Nikolay; Becker, Jens E.; Becker, Jurgen

    2005-01-01

    A Network-on-Chip (NoC) is an energy-efficient onchip communication architecture for Multi-Processor Systemon- Chip (MPSoC) architectures. In earlier papers we proposed two Network-on-Chip architectures based on packet-switching and circuit-switching. In this paper we derive an energy model for both NoC architectures to predict their energy consumption per transported bit. Both architectures are also compared with a traditional bus architecture. The energy model is primarily needed to find a ...

  17. Energy Model of Networks-on-Chip and a Bus

    OpenAIRE

    Wolkotte, Pascal T.; Smit, Gerard J.M.; Kavaldjiev, Nikolay; Becker, Jens E.; Becker, Jürgen

    2005-01-01

    A Network-on-Chip (NoC) is an energy-efficient onchip communication architecture for Multi-Processor Systemon-Chip (MPSoC) architectures. In earlier papers we proposed two Network-on-Chip architectures based on packet-switching and circuit-switching. In this paper we derive an energy model for both NoC architectures to predict their energy consumption per transported bit. Both architectures are also compared with a traditional bus architecture. The energy model is primarily needed to find a n...

  18. DC Bus Regulation with a Flywheel Energy Storage System

    Science.gov (United States)

    Kenny, Barbara H.; Kascak, Peter E.

    2003-01-01

    This paper describes the DC bus regulation control algorithm for the NASA flywheel energy storage system during charge, charge reduction and discharge modes of operation. The algorithm was experimentally verified with results given in a previous paper. This paper presents the necessary models for simulation with detailed block diagrams of the controller algorithm. It is shown that the flywheel system and the controller can be modeled in three levels of detail depending on the type of analysis required. The three models are explained and then compared using simulation results.

  19. Distributed Data Acquisition and Control by Software Bus

    Institute of Scientific and Technical Information of China (English)

    Cecil Bruce-Boye; Dmitry A. Kazakov

    2004-01-01

    Increasing global competition forces manufacturers of products from all technical fields to guarantee a high product quality for a long period of time. At the same time it is necessary to minimize production costs. In order to meet all these requirements, on-line data acquisition and processing are of increasing importance in distributed automation systems. A software bus operating on industrial Ethernet has an ability to minimize operating costs by offering easy installation, scalability,high degree of reliability and remote monitoring and control.

  20. DNAM-1 Expression Marks an Alternative Program of NK Cell Maturation

    Directory of Open Access Journals (Sweden)

    Ludovic Martinet

    2015-04-01

    Full Text Available Natural killer (NK cells comprise a heterogeneous population of cells important for pathogen defense and cancer surveillance. However, the functional significance of this diversity is not fully understood. Here, we demonstrate through transcriptional profiling and functional studies that the activating receptor DNAM-1 (CD226 identifies two distinct NK cell functional subsets: DNAM-1+ and DNAM-1− NK cells. DNAM-1+ NK cells produce high levels of inflammatory cytokines, have enhanced interleukin 15 signaling, and proliferate vigorously. By contrast, DNAM-1− NK cells that differentiate from DNAM-1+ NK cells have greater expression of NK-cell-receptor-related genes and are higher producers of MIP1 chemokines. Collectively, our data reveal the existence of a functional program of NK cell maturation marked by DNAM-1 expression.

  1. Bus Stops, Bus stops created from hard copy CAT transit maps. Includes information on if there is a shelter present or not., Published in 2010, 1:4800 (1in=400ft) scale, City of Bismarck.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Bus Stops dataset, published at 1:4800 (1in=400ft) scale, was produced all or in part from Hardcopy Maps information as of 2010. It is described as 'Bus stops...

  2. Aging of perennial cells and organ parts according to the programmed aging paradigm.

    Science.gov (United States)

    Libertini, Giacinto; Ferrara, Nicola

    2016-04-01

    If aging is a physiological phenomenon-as maintained by the programmed aging paradigm-it must be caused by specific genetically determined and regulated mechanisms, which must be confirmed by evidence. Within the programmed aging paradigm, a complete proposal starts from the observation that cells, tissues, and organs show continuous turnover: As telomere shortening determines both limits to cell replication and a progressive impairment of cellular functions, a progressive decline in age-related fitness decline (i.e., aging) is a clear consequence. Against this hypothesis, a critic might argue that there are cells (most types of neurons) and organ parts (crystalline core and tooth enamel) that have no turnover and are subject to wear or manifest alterations similar to those of cells with turnover. In this review, it is shown how cell types without turnover appear to be strictly dependent on cells subjected to turnover. The loss or weakening of the functions fulfilled by these cells with turnover, due to telomere shortening and turnover slowing, compromises the vitality of the served cells without turnover. This determines well-known clinical manifestations, which in their early forms are described as distinct diseases (e.g., Alzheimer's disease, Parkinson's disease, age-related macular degeneration, etc.). Moreover, for the two organ parts (crystalline core and tooth enamel) without viable cells or any cell turnover, it is discussed how this is entirely compatible with the programmed aging paradigm.

  3. Long-term in vivo provision of antigen-specific T cell immunity by programming hematopoietic stem cells

    Science.gov (United States)

    Yang, Lili; Baltimore, David

    2005-03-01

    A method to genetically program mouse hematopoietic stem cells to develop into functional CD8 or CD4 T cells of defined specificity in vivo is described. For this purpose, a bicistronic retroviral vector was engineered that efficiently delivers genes for both and chains of T cell receptor (TCR) to hematopoietic stem cells. When modified cell populations were used to reconstruct the hematopoietic lineages of recipient mice, significant percentages of antigen-specific CD8 or CD4 T cells were observed. These cells expressed normal surface markers and responded to peptide antigen stimulation by proliferation and cytokine production. Moreover, they could mature into memory cells after peptide stimulation. Using TCRs specific for a model tumor antigen, we found that the recipient mice were able to partially resist a challenge with tumor cells carrying the antigen. By combining cells modified with CD8- and CD4-specific TCRs, and boosting with dendritic cells pulsed with cognate peptides, complete suppression of tumor could be achieved and even tumors that had become established would regress and be eliminated after dendritic cell/peptide immunization. This methodology of "instructive immunotherapy" could be developed for controlling the growth of human tumors and attacking established pathogens.

  4. Using microfluidics to study programmed cell death: A new approach

    DEFF Research Database (Denmark)

    Mark, Christina; Zor, Kinga; Heiskanen, Arto;

    to approach in vivo conditions. Microfluidics also allow implementation of a wide range of electrochemical or optical assays for online, real-time, parallel analysis of important parameters such as redox activity, O2 and H2O2 concentration, extracellular pH, cell viability and enzyme activity1,2. Currently...

  5. Internet and Cell Phone Based Smoking Cessation Programs among Adolescents

    Science.gov (United States)

    Mehta, Purvi; Sharma, Manoj

    2010-01-01

    Smoking cessation among adolescents is a salient public health issue, as it can prevent the adoption of risky health behaviors and reduce negative impacts on health. Self-efficacy, household and social support systems, and perceived benefits are some important cessation determinants. With the popular use of the Internet and cell phone usage among…

  6. Control of the meiotic cell division program in plants

    NARCIS (Netherlands)

    Wijnker, T.G.; Schnittger, A.

    2013-01-01

    While the question of why organisms reproduce sexually is still a matter of controversy, it is clear that the foundation of sexual reproduction is the formation of gametes with half the genomic DNA content of a somatic cell. This reduction in genomic content is accomplished through meiosis that, in

  7. Bus Stops, Maryland Transit Administration Local and Commuter Bus Stops, Published in 2013, 1:24000 (1in=2000ft) scale, Maryland Transit Administration.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Bus Stops dataset, published at 1:24000 (1in=2000ft) scale, was produced all or in part from Other information as of 2013. It is described as 'Maryland Transit...

  8. Bus Routes, This shapefile contains lines that follow the path of the existing bus routes, Published in 2006, Charlotte Area Transit System.

    Data.gov (United States)

    NSGIC GIS Inventory (aka Ramona) — This Bus Routes dataset, was produced all or in part from Other information as of 2006. It is described as 'This shapefile contains lines that follow the path of...

  9. Deciphering the transcriptional switches of innate lymphoid cell programming: the right factors at the right time

    OpenAIRE

    Lim, Alfred W.Y.; McKenzie, Andrew N.J.

    2015-01-01

    Innate lymphoid cells (ILCs) are increasingly recognised as an innate immune counterpart of adaptive TH cells. In addition to their similar effector cytokine production, there is a strong parallel between the transcription factors that control the differentiation of TH1, TH2 and TH17 cells and ILC Groups 1, 2 and 3, respectively. Here, we review the transcriptional circuit that specifies the development of a common ILC progenitor and its subsequent programming into distinct ILC groups. Notch,...

  10. Research of CAN bus test mode based on C8051F040%基于C8051F040单片机的CAN总线测试模式研究

    Institute of Scientific and Technical Information of China (English)

    张辉

    2012-01-01

    Fieldbus has become the hot-spot in the data bus field. CAN bus is recognized to be one of the most prospective field-buses. The design and debugging of CAN bus node is the focal point in CAN bus communication system design. The CAN controller integrated in C8051F040 is introduced. A CAN communication node is designed base on C8051F040. The software design program of CAN node test mode is presented. It can be used to test CAN bus modules and save the testing time.%现场总线已成为数据总线领域中最为活跃的热点,CAN总线被公认为最有前途的现场总线之一,CAN总线节点的设计、调试是CAN总线通讯系统设计的重点.在此介绍了C8051F040单片机内部集成的CAN控制器,并基于C8051F040单片机设计了一个CAN通信节点,并给出了CAN节点测试模式软件设计程序,可以用于CAN总线模块的测试,节省测试时间.

  11. THE USE OF MATHEMATICAL PROGRAMING TO SOLVE CERTAIN PROBLEMS IN PUBLIC SCHOOL TRANSPORTATION.

    Science.gov (United States)

    BOYER, ROSCOE A.

    A PROGRAM THAT WOULD DEVISE OPTIMAL ROUTES FOR SCHOOL BUSES WAS DEVELOPED. ONE OF THE TWO MODELS DEVELOPED FOR THIS STUDY, CALLED THE HEURISTIC MODEL, WAS A HAND PROCEDURE BASED ON THE ASSUMPTION THAT, IN AN EFFICIENT SCHOOL BUS SYSTEM, STUDENT MILES SHOULD BE MINIMIZED RATHER THAN BUS MILES. THE OTHER MODEL WAS DESIGNED TO BE USED WITH HIGH SPEED…

  12. UNIVERSALIZATION OF BUS BODY FACING DETAILS AND PRODUCTION TOOLING FOR THEIR MANUFACTURING

    Directory of Open Access Journals (Sweden)

    M. Taranenko

    2009-01-01

    Full Text Available The directions concerning bus body production costs reduction based on large-size facing details stamping on electric-hydraulic presses are considered. The engineering of unified large-size facing detail blanks, manufacturing processes and variants of unified technological tooling for bus body facing details production, including simple- or multi-type details are described.

  13. 49 CFR 571.131 - Standard No. 131; School bus pedestrian safety devices.

    Science.gov (United States)

    2010-10-01

    ... devices. S1. Scope. This standard establishes requirements for devices that can be installed on school... a stopped school bus and striking pedestrians in the vicinity of the bus. S3. Application. This standard applies to school buses other than multifunction school activity buses. S4. Definitions....

  14. Evoking Emotions and Unpacking Layered Histories through Young Children's Illustrations of Racial Bus Segregation

    Science.gov (United States)

    Kuby, Candace R.

    2013-01-01

    Drawing on theories of multi-modality and critical visual literacy, this article focuses on images that five-and six year-olds painted in a class-made book, Voice on the Bus, about racial segregation. The article discusses how children used illustrations to convey their understandings of Rosa Parks' bus arrest in Alabama. A post-structural view…

  15. Reducing transit bus emissions: Alternative fuels or traffic operations?

    Science.gov (United States)

    Alam, Ahsan; Hatzopoulou, Marianne

    2014-06-01

    In this study, we simulated the operations and greenhouse gas (GHG) emissions of transit buses along a busy corridor and quantified the effects of two different fuels (conventional diesel and compressed natural gas) as well as a set of driving conditions on emissions. Results indicate that compressed natural gas (CNG) reduces GHG emissions by 8-12% compared to conventional diesel, this reduction could increase to 16% with high levels of traffic congestion. However, the benefits of switching from conventional diesel to CNG are less apparent when the road network is uncongested. We also investigated the effects of bus operations on emissions by applying several strategies such as transit signal priority (TSP), queue jumper lanes, and relocation of bus stops. Results show that in congested conditions, TSP alone can reduce GHG emissions by 14% and when combined with improved technology; a reduction of 23% is achieved. The reduction benefits are even more apparent when other transit operational improvements are combined with TSP. Finally a sensitivity analysis was performed to investigate the effect of operational improvements on emissions under varying levels of network congestion. We observe that under “extreme congestion”, the benefits of TSP decrease.

  16. Genetic algorithm for optimization in adaptive bus signal priority control

    Directory of Open Access Journals (Sweden)

    Tran Vu TU

    2013-01-01

    Full Text Available This paper firstly proposes an improved genetic algorithm (GA for optimization in adaptive bus signal priority control at signalized intersections. Unlike conventional genetic algorithms with slow convergence speed, this algorithm can increase the convergence speed by utilizing the compensation rule between consecutive signal cycles to narrow new possible generated population spaces. Secondly, the paper would like to present a way to apply the algorithm to a simple adaptive bus signal priority control as well as compare how much the computation time is saved when applying the improved algorithm. Then the research thirdly investigates the efficiency of the proposed algorithm under various flow rate situations. The results show that the improved genetic algorithm can reduce the computation time considerably, by up to 48.39% for the studied case. With high saturation degrees on the cross street, the convergence rate performance of the improved genetic algorithm is significantly good. The figure can be up to 36.2% when compared with the convergence rate of the conventional GA.

  17. Bus Rapid Transit (BRT System Impacts to Environmental Quality

    Directory of Open Access Journals (Sweden)

    Mojtaba Shojaei Baghini

    2014-02-01

    Full Text Available The aim of this research is to examine the mechanism and performance of Bus Rapid Transit (BRT system and its impacts on environment quality. Environment quality is an indicator of regional quality of life, supporting the health and well-being of the public and sustainability of the urban and natural environment. Transit agencies are adopting vehicles with alternative fuels, propulsion systems and pollutant emissions controls. One of the ways to improve the transportation environment is through the reduction of BRT emissions to improve air quality. The primary advantage of Bus Rapid Transit (BRT system is that it can be adapted to a multitude of operating environments, with sufficient scalability to deliver increased carrying capacity to meet future ridership growth. Moreover, the system will also likely reduce overall the noise levels by determining suitable noise management systems. The paper finds that a BRT system offers the greatest potential for greenhouse gas reductions primarily because BRT vehicles generally offer lower CO2 emissions per passenger mile than other transportation system.

  18. CERPEN FARUK “BUS KOTA” DALAM SEMIOTIK ROLAND BARTHES

    Directory of Open Access Journals (Sweden)

    Ken Widyatwati

    2016-04-01

    Full Text Available Literature called beautiful if it contains the mandate, message, ideas and meanings that are useful for the readers. Short story “Bus Kota” (City Bus containing the mandate, message, ideas and meanings that are useful to the reader. The mandate will be revealed by Roland Barthes' semiotic theory in the book S/Z. Literature has its own allure and text have accrued but not due to independence because of the difference in quality. Texts merge into a unity, or restore any text not as an individual but as a form of plurality. Literature as part of a social system is an expression of the author's sense of the outpouring of public life. Literary works can express themselves in the author's view the social and cultural changes in society because of the development of information technology and rapid. Technological developments and socio-cultural information can change in society so as to affect the psychology of the people. Society must have a thickness of faith not only for themselves, but to be able to maintain equanimity in the life of a pluralistic society

  19. Bus Implementation Using New Low Power PFSCL Tristate Buffers

    Directory of Open Access Journals (Sweden)

    Neeta Pandey

    2016-01-01

    Full Text Available This paper proposes new positive feedback source coupled logic (PFSCL tristate buffers suited to bus applications. The proposed buffers use switch to attain high impedance state and modify the load or the current source section. An interesting consequence of this is overall reduction in the power consumption. The proposed tristate buffers consume half the power compared to the available switch based counterpart. The issues with available PFSCL tristate buffers based bus implementation are identified and benefits of employing the proposed tristate buffer topologies are put forward. SPICE simulation results using TSMC 180 nm CMOS technology parameters are included to support the theoretical formulations. The performance of proposed tristate buffer topologies is examined on the basis of propagation delay, output enable time, and power consumption. It is found that one of the proposed tristate buffer topology outperforms the others in terms of all the performance parameters. An examination of behavior of available and the proposed PFSCL tristate buffer topologies under parameter variations and mismatch shows a maximum variation of 14%.

  20. Studying customer loyalty at Daewoo express bus service, Pakistan

    Directory of Open Access Journals (Sweden)

    Usman Yousaf

    2013-09-01

    Full Text Available Background: Meeting service quality standards and striving for loyalty are two critical areas which have until now been overlooked by both the passenger transport industry and academia in Pakistan therefore the study sheds useful light on an issue hitherto untouched. Therefore increased sample size will help in increasing generalizability of study. Methods: This paper is designed to study the level of loyalty at Daewoo Express Bus Service in Sargodha by measuring customer satisfaction. Researchers used a small sample of only 96 respondents (passengers and only studies customer's behavior in the service quality of Daewoo Express Bus Service however it may differ in other passenger transport services. Results and conclusions: This paper reveals that there is a positive and significant relationship between loyalty (dependant variable and price perceptions, reliability, retrieving and smoothing (independent variables. However, the study found that reliability of services is the most important dimension among other independent variables (price perceptions, smoothing, reliability, retrieving effecting customers loyalty at Daewoo Express. Paper under consideration would surely assist Daewoo`s management team to take care of the loopholes existing in the current service level and likely threats which Daewoo might face.

  1. A shift to organismal stress resistance in programmed cell death mutants.

    Directory of Open Access Journals (Sweden)

    Meredith E Judy

    Full Text Available Animals have many ways of protecting themselves against stress; for example, they can induce animal-wide, stress-protective pathways and they can kill damaged cells via apoptosis. We have discovered an unexpected regulatory relationship between these two types of stress responses. We find that C. elegans mutations blocking the normal course of programmed cell death and clearance confer animal-wide resistance to a specific set of environmental stressors; namely, ER, heat and osmotic stress. Remarkably, this pattern of stress resistance is induced by mutations that affect cell death in different ways, including ced-3 (cell death defective mutations, which block programmed cell death, ced-1 and ced-2 mutations, which prevent the engulfment of dying cells, and progranulin (pgrn-1 mutations, which accelerate the clearance of apoptotic cells. Stress resistance conferred by ced and pgrn-1 mutations is not additive and these mutants share altered patterns of gene expression, suggesting that they may act within the same pathway to achieve stress resistance. Together, our findings demonstrate that programmed cell death effectors influence the degree to which C. elegans tolerates environmental stress. While the mechanism is not entirely clear, it is intriguing that animals lacking the ability to efficiently and correctly remove dying cells should switch to a more global animal-wide system of stress resistance.

  2. Study on the optimum design of bus window pillar join40t; Bus window pillar ketsugo buzai no saiteki sekkei ni kansuru kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    Tomioka, N. [Nihon University, Tokyo (Japan); Lim, S.; Kim, M.; Lee, H.; Kang, S.; Bae, D.

    1997-10-01

    Automobile body structure is generally assembled using various spot welded box sectional members. Especially, in the case of the bus, the shape of window pillar joint is assembled m T-type. This T-type member has some problem such as high stress concentration, low fatigue strength and structural rigidity. Therefore, in this report, performed a study on the optimum design of the bus window pillar joint for such problem by FEM analysis and experiments. 1 ref., 10 figs., 2 tabs.

  3. Programming of regulatory T cells from pluripotent stem cells and prevention of autoimmunity*

    OpenAIRE

    Haque, Rizwanul; Lei, Fengyang; Xiong, Xiaofang; Bian, Yanqing; Zhao, Baohua; Wu, Yuzhang; Song, Jianxun

    2012-01-01

    Regulatory T (Treg) cells are being used to treat autoimmunity and prevent organ rejection; however, Treg cell-based therapies have been hampered by the technical limitation in obtaining a high number of functional Treg cells. Here we show how to generate functional Treg cells from induced pluripotent stem (iPS) cells, and to determine the potential role of such cells for Treg-based immunotherapy against autoimmunity in a therapeutic setting. Ligation of a Notch ligand and transduction of the...

  4. Stem cell signaling. An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control.

    Science.gov (United States)

    Clevers, Hans; Loh, Kyle M; Nusse, Roel

    2014-10-01

    Stem cells fuel tissue development, renewal, and regeneration, and these activities are controlled by the local stem cell microenvironment, the "niche." Wnt signals emanating from the niche can act as self-renewal factors for stem cells in multiple mammalian tissues. Wnt proteins are lipid-modified, which constrains them to act as short-range cellular signals. The locality of Wnt signaling dictates that stem cells exiting the Wnt signaling domain differentiate, spatially delimiting the niche in certain tissues. In some instances, stem cells may act as or generate their own niche, enabling the self-organization of patterned tissues. In this Review, we discuss the various ways by which Wnt operates in stem cell control and, in doing so, identify an integral program for tissue renewal and regeneration.

  5. DCD – a novel plant specific domain in proteins involved in development and programmed cell death

    Directory of Open Access Journals (Sweden)

    Doerks Tobias

    2005-07-01

    Full Text Available Abstract Background Recognition of microbial pathogens by plants triggers the hypersensitive reaction, a common form of programmed cell death in plants. These dying cells generate signals that activate the plant immune system and alarm the neighboring cells as well as the whole plant to activate defense responses to limit the spread of the pathogen. The molecular mechanisms behind the hypersensitive reaction are largely unknown except for the recognition process of pathogens. We delineate the NRP-gene in soybean, which is specifically induced during this programmed cell death and contains a novel protein domain, which is commonly found in different plant proteins. Results The sequence analysis of the protein, encoded by the NRP-gene from soybean, led to the identification of a novel domain, which we named DCD, because it is found in plant proteins involved in development and cell death. The domain is shared by several proteins in the Arabidopsis and the rice genomes, which otherwise show a different protein architecture. Biological studies indicate a role of these proteins in phytohormone response, embryo development and programmed cell by pathogens or ozone. Conclusion It is tempting to speculate, that the DCD domain mediates signaling in plant development and programmed cell death and could thus be used to identify interacting proteins to gain further molecular insights into these processes.

  6. A Study of BUS Architecture Design for Controller of Nuclear Power Plant Using FPGA

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Dongil; Yun, Donghwa; Hwang, Sungjae; Kim, Myeongyun; Lee, Dongyun [PONUTech Co. Ltd., Seoul (Korea, Republic of)

    2014-05-15

    CPU (Central Processing Unit) operating speed and communication rate have been more technically improved than before. However, whole system is been a degradation of performance by electronic and structural limitation of parallel bus. Transmission quantity and speed have a limit and need arbiter in order to do arbitration because several boards shared parallel bus. Arbiter is a high complexity in implementing so it increases component per chip. If a parallel bus uses, it will occurs some problems what are reflection noise, power/ground noise (or ground bounce) as SSN (Simultaneous Switching Noise) and crosstalk noise like magnetic coupling. In this paper, in order to solve a problem of parallel bus in controller of NPP (Nuclear Power Plant), proposes the bus architecture design using FPGA (Field Programmable Gate Array) based on LVDS (Low Voltage Differential Signaling)

  7. On-site cell field test support program

    Science.gov (United States)

    Staniunas, J. W.; Merten, G. P.

    1982-09-01

    Utility sites for data monitoring were reviewed and selected. Each of these sites will be instrumented and its energy requirements monitored and analyzed for one year prior to the selection of 40 Kilowatt fuel cell field test sites. Analyses in support of the selection of sites for instrumentation shows that many building sectors offered considerable market potential. These sectors include nursing home, health club, restaurant, industrial, hotel/motel and apartment.

  8. Molecular Programming of Tumor-Infiltrating CD8+ T Cells and IL15 Resistance.

    Science.gov (United States)

    Doedens, Andrew L; Rubinstein, Mark P; Gross, Emilie T; Best, J Adam; Craig, David H; Baker, Megan K; Cole, David J; Bui, Jack D; Goldrath, Ananda W

    2016-09-01

    Despite clinical potential and recent advances, durable immunotherapeutic ablation of solid tumors is not routinely achieved. IL15 expands natural killer cell (NK), natural killer T cell (NKT) and CD8(+) T-cell numbers and engages the cytotoxic program, and thus is under evaluation for potentiation of cancer immunotherapy. We found that short-term therapy with IL15 bound to soluble IL15 receptor α-Fc (IL15cx; a form of IL15 with increased half-life and activity) was ineffective in the treatment of autochthonous PyMT murine mammary tumors, despite abundant CD8(+) T-cell infiltration. Probing of this poor responsiveness revealed that IL15cx only weakly activated intratumoral CD8(+) T cells, even though cells in the lung and spleen were activated and dramatically expanded. Tumor-infiltrating CD8(+) T cells exhibited cell-extrinsic and cell-intrinsic resistance to IL15. Our data showed that in the case of persistent viral or tumor antigen, single-agent systemic IL15cx treatment primarily expanded antigen-irrelevant or extratumoral CD8(+) T cells. We identified exhaustion, tissue-resident memory, and tumor-specific molecules expressed in tumor-infiltrating CD8(+) T cells, which may allow therapeutic targeting or programming of specific subsets to evade loss of function and cytokine resistance, and, in turn, increase the efficacy of IL2/15 adjuvant cytokine therapy. Cancer Immunol Res; 4(9); 799-811. ©2016 AACR.

  9. Homeostatic Mass Control in Gastric Non-Neoplastic Epithelia under Infection of Helicobacter pylori: An Immunohistochemical Analysis of Cell Growth, Stem Cells and Programmed Cell Death

    International Nuclear Information System (INIS)

    We evaluated homeostatic mass control in non-neoplastic gastric epithelia under Helicobacter pylori (HP) infection in the macroscopically normal-appearing mucosa resected from the stomach with gastric cancer, immunohistochemically analyzing the proliferation, kinetics of stem cells and programmed cell death occurring in them. Ki67 antigen-positive proliferating cells were found dominantly in the elongated neck portion, sparsely in the fundic areas and sporadically in the stroma with chronic infiltrates. CD117 could monitor the kinetics of gastric stem cells and showed its expression in two stages of gastric epithelial differentiation, namely, in transient cells from the gastric epithelial stem cells to the foveolar and glandular cells in the neck portion and in what are apparently progenitor cells from the gastric stem cells in the stroma among the infiltrates. Most of the nuclei were positive for ssDNA in the almost normal mucosa, suggesting DNA damage. Cleaved caspase-3-positive foveolar cells were noted under the surface, suggesting the suppression of apoptosis in the surface foveolar cells. Besides such apoptosis of the foveolar cells, in the severely inflamed mucosa apoptotic cells were found in the neck portion where most of the cells were Ki67 antigen-positive proliferating cells. Beclin-1 was recognized in the cytoplasm and in a few nuclei of the fundic glandular cells, suggesting their autophagic cell death and mutated beclin-1 in the nuclei. Taken together, the direct and indirect effects of HP infection on the gastric epithelial proliferation, differentiation and programmed cell death suggested the in-situ occurrence of gastric cancer under HP infection

  10. Vibrio cholerae Porin OmpU Induces Caspase-independent Programmed Cell Death upon Translocation to the Host Cell Mitochondria.

    Science.gov (United States)

    Gupta, Shelly; Prasad, G V R Krishna; Mukhopadhaya, Arunika

    2015-12-25

    Porins, a major class of outer membrane proteins in Gram-negative bacteria, primarily act as transport channels. OmpU is one of the major porins of human pathogen, Vibrio cholerae. In the present study, we show that V. cholerae OmpU has the ability to induce target cell death. Although OmpU-mediated cell death shows some characteristics of apoptosis, such as flipping of phosphatidylserine in the membrane as well as cell size shrinkage and increased cell granularity, it does not show the caspase-3 activation and DNA laddering pattern typical of apoptotic cells. Increased release of lactate dehydrogenase in OmpU-treated cells indicates that the OmpU-mediated cell death also has characteristics of necrosis. Further, we show that the mechanism of OmpU-mediated cell death involves major mitochondrial changes in the target cells. We observe that OmpU treatment leads to the disruption of mitochondrial membrane potential, resulting in the release of cytochrome c and apoptosis-inducing factor (AIF). AIF translocates to the host cell nucleus, implying that it has a crucial role in OmpU-mediated cell death. Finally, we observe that OmpU translocates to the target cell mitochondria, where it directly initiates mitochondrial changes leading to mitochondrial membrane permeability transition and AIF release. Partial blocking of AIF release by cyclosporine A in OmpU-treated cells further suggests that OmpU may be inducing the opening of the mitochondrial permeability transition pore. All of these results lead us to the conclusion that OmpU induces cell death in target cells in a programmed manner in which mitochondria play a central role.

  11. Repetitive elements dynamics in cell identity programming, maintenance and disease

    KAUST Repository

    Bodega, Beatrice

    2014-12-01

    The days of \\'junk DNA\\' seem to be over. The rapid progress of genomics technologies has been unveiling unexpected mechanisms by which repetitive DNA and in particular transposable elements (TEs) have evolved, becoming key issues in understanding genome structure and function. Indeed, rather than \\'parasites\\', recent findings strongly suggest that TEs may have a positive function by contributing to tissue specific transcriptional programs, in particular as enhancer-like elements and/or modules for regulation of higher order chromatin structure. Further, it appears that during development and aging genomes experience several waves of TEs activation, and this contributes to individual genome shaping during lifetime. Interestingly, TEs activity is major target of epigenomic regulation. These findings are shedding new light on the genome-phenotype relationship and set the premises to help to explain complex disease manifestation, as consequence of TEs activity deregulation.

  12. Involvement of phospholipase D-related signal transduction in chemical-induced programmed cell death in tomato cell cultures

    NARCIS (Netherlands)

    Iakimova, E.T.; Michaeli, R.; Woltering, E.J.

    2013-01-01

    Phospholipase D (PLD) and its product phosphatidic acid (PA) are incorporated in a complex metabolic network in which the individual PLD isoforms are suggested to regulate specific developmental and stress responses, including plant programmed cell death (PCD). Despite the accumulating knowledge, th

  13. RADIATION THERAPY ONCOLOGY GROUP TRANSLATIONAL RESEARCH PROGRAM STEM CELL SYMPOSIUM : INCORPORATING STEM CELL HYPOTHESES INTO CLINICAL TRIALS

    NARCIS (Netherlands)

    Woodward, Wendy A.; Bristow, Robert G.; Clarke, Michael F.; Coppes, Robert P.; Cristofanilli, Massimo; Duda, Dan G.; Fike, John R.; Hambardzumyan, Dolores; Hill, Richard P.; Jordan, Craig T.; Milas, Luka; Pajonk, Frank; Curran, Walter J.; Dicker, Adam P.; Chen, Yuhchyau

    2009-01-01

    At a meeting of the Translation Research Program of the Radiation Therapy Oncology Group held in early 2008, attendees focused on updating the current state of knowledge in cancer stem cell research and discussing ways in which this knowledge can be translated into clinical use across all disease si

  14. Changes of Respiration Activities in Cells of Winter Wheat and Sugar Cane Suspension Cultures During Programmed Cell Death Process

    OpenAIRE

    I.V. Lyubushkina; A.V. Fedyaeva; Stepanov, A.V.; T.P. Pobezhimova

    2015-01-01

    Process of cell death in suspension cultures of winter wheat and sugar cane under high (50 °С) and negative (-8 °С) temperature treatment has been studied. It has been shown, that programmed cell death (PCD) process caused by the negative temperature in the culture of winter wheat was noted for slow rate of realization and it was carried out for 10 days. It has been state that rate of cell respiration was significantly higher than in the control culture. At the same time PCD processes induced...

  15. Programs.

    Science.gov (United States)

    Community College Journal, 1996

    1996-01-01

    Includes a collection of eight short articles describing model community college programs. Discusses a literacy program, a mobile computer classroom, a support program for at-risk students, a timber-harvesting program, a multimedia presentation on successful women graduates, a career center, a collaboration with NASA, and an Israeli engineering…

  16. Virtual reality based support system for layout planning and programming of an industrial robotic work cell.

    Science.gov (United States)

    Yap, Hwa Jen; Taha, Zahari; Dawal, Siti Zawiah Md; Chang, Siow-Wee

    2014-01-01

    Traditional robotic work cell design and programming are considered inefficient and outdated in current industrial and market demands. In this research, virtual reality (VR) technology is used to improve human-robot interface, whereby complicated commands or programming knowledge is not required. The proposed solution, known as VR-based Programming of a Robotic Work Cell (VR-Rocell), consists of two sub-programmes, which are VR-Robotic Work Cell Layout (VR-RoWL) and VR-based Robot Teaching System (VR-RoT). VR-RoWL is developed to assign the layout design for an industrial robotic work cell, whereby VR-RoT is developed to overcome safety issues and lack of trained personnel in robot programming. Simple and user-friendly interfaces are designed for inexperienced users to generate robot commands without damaging the robot or interrupting the production line. The user is able to attempt numerous times to attain an optimum solution. A case study is conducted in the Robotics Laboratory to assemble an electronics casing and it is found that the output models are compatible with commercial software without loss of information. Furthermore, the generated KUKA commands are workable when loaded into a commercial simulator. The operation of the actual robotic work cell shows that the errors may be due to the dynamics of the KUKA robot rather than the accuracy of the generated programme. Therefore, it is concluded that the virtual reality based solution approach can be implemented in an industrial robotic work cell.

  17. Cell-based composite materials with programmed structures and functions

    Energy Technology Data Exchange (ETDEWEB)

    None

    2016-03-01

    The present invention is directed to the use of silicic acid to transform biological materials, including cellular architecture into inorganic materials to provide biocomposites (nanomaterials) with stabilized structure and function. In the present invention, there has been discovered a means to stabilize the structure and function of biological materials, including cells, biomolecules, peptides, proteins (especially including enzymes), lipids, lipid vesicles, polysaccharides, cytoskeletal filaments, tissue and organs with silicic acid such that these materials may be used as biocomposites. In many instances, these materials retain their original biological activity and may be used in harsh conditions which would otherwise destroy the integrity of the biological material. In certain instances, these biomaterials may be storage stable for long periods of time and reconstituted after storage to return the biological material back to its original form. In addition, by exposing an entire cell to form CSCs, the CSCs may function to provide a unique system to study enzymes or a cascade of enzymes which are otherwise unavailable.

  18. Vehicle Technologies and Fuel Cell Technologies Program: Prospective Benefits Assessment Report for Fiscal Year 2016

    Energy Technology Data Exchange (ETDEWEB)

    Stephens, T. S. [Argonne National Lab. (ANL), Argonne, IL (United States); Taylor, C. H. [TA Engineering, Inc., Catonsville, MD (United States); Moore, J. S. [TA Engineering, Inc., Catonsville, MD (United States); Ward, J. [United States Department of Energy, Washington, DC (United States). Office of Energy Efficiency and Renewable Energy

    2016-02-23

    Under a diverse set of programs, the Vehicle Technologies and Fuel Cell Technologies offices of DOE’s Office of Energy Efficiency and Renewable Energy invest in research, development, demonstration, and deployment of advanced vehicle, hydrogen production, delivery and storage, and fuel cell technologies. This report estimates the benefits of successfully developing and deploying these technologies (a “Program Success” case) relative to a base case (the “No Program” case). The Program Success case represents the future with completely successful deployment of Vehicle Technologies Office (VTO) and Fuel Cell Technologies Office (FCTO) technologies. The No Program case represents a future in which there is no contribution after FY 2016 by the VTO or FCTO to these technologies. The benefits of advanced vehicle, hydrogen production, delivery and storage, and fuel cell technologies were estimated on the basis of differences in fuel use, primary energy use, and greenhouse gas (GHG) emissions from light-, medium- and heavy-duty vehicles, including energy and emissions from fuel production, between the base case and the Program Success case. Improvements in fuel economy of various vehicle types, growth in the stock of fuel cell vehicles and other advanced technology vehicles, and decreased GHG intensity of hydrogen production and delivery in the Program Success case over the No Program case were projected to result in savings in petroleum use and GHG emissions. Benefits were disaggregated by individual program technology areas, which included the FCTO program and the VTO subprograms of batteries and electric drives; advanced combustion engines; fuels and lubricants; materials (for reduction in vehicle mass, or “lightweighting”); and, for medium- and heavy-duty vehicles, reduction in rolling and aerodynamic resistance. Projections for the Program Success case indicate that by 2035, the average fuel economy of on-road, light-duty vehicle stock could be 47% to 76

  19. RADARSAT program

    Science.gov (United States)

    Mcnally, J.; Parashar, S.

    1993-01-01

    Work on the RADARSAT system is progressing towards the currently scheduled launch date of early 1995. The spacecraft bus and the Synthetic Aperture Radar (SAR) payload are at various stages of development. Requirements for the ground segment have been mostly established. The design of the ground elements such as the mission control facility and the SAR data processor is underway. The SAR applications development work is continuing and the chosen distributor, RADARSAT International Inc. (RSI) is making preparations to market RADARSAT data internationally. A plan for the follow-on to RADARSAT 1 is being finalized to ensure continuity of SAR data under the Radarsat program.

  20. A transgenic mouse marking live replicating cells reveals in vivo transcriptional program of proliferation

    DEFF Research Database (Denmark)

    Klochendler, Agnes; Weinberg-Corem, Noa; Moran, Maya;

    2012-01-01

    biological material. We describe a transgenic mouse strain, expressing a CyclinB1-GFP fusion reporter, that marks replicating cells in the S/G2/M phases of the cell cycle. Using flow cytometry, we isolate live replicating cells from the liver and compare their transcriptome to that of quiescent cells to......Most adult mammalian tissues are quiescent, with rare cell divisions serving to maintain homeostasis. At present, the isolation and study of replicating cells from their in vivo niche typically involves immunostaining for intracellular markers of proliferation, causing the loss of sensitive...... reveal gene expression programs associated with cell proliferation in vivo. We find that replicating hepatocytes have reduced expression of genes characteristic of liver differentiation. This reporter system provides a powerful platform for gene expression and metabolic and functional studies of...

  1. Developing a Natural Gas-Powered Bus Rapid Transit Service: A Case Study

    Energy Technology Data Exchange (ETDEWEB)

    Mitchell, G.

    2015-11-03

    The Roaring Fork Transit Authority (RFTA) and its VelociRFTA Bus Rapid Transit (BRT) program are unique in many ways. For example, VelociRFTA was the first rural BRT system in the United States and the operational environment of the VelociRFTA BRT is one of the most severe in the country, with extreme winter temperatures and altitudes close to 8,000 feet. RFTA viewed high altitude operation as the most challenging characteristic when it began considering the use of natural gas. RFTA is the second-largest public transit system in Colorado behind Denver's Regional Transportation District (RTD), and it is one of the largest rural public transit systems in the country. In 2013, RFTA accepted delivery of 22 new compressed natural gas (CNG) buses that went into service after completion of maintenance and refueling facilities earlier that year. This paper examines the lessons learned from RFTA's experience of investigating--and ultimately choosing--CNG for their new BRT program and focuses on the unique environment of RFTA's BRT application; the decision process to include CNG fueling in the project; unforeseen difficulties encountered in the operation of CNG buses; public perception; cost comparison to competing fuels; and considerations for indoor fueling facilities and project funding.

  2. Developing a Natural Gas-Powered Bus Rapid Transit Service. A Case Study

    Energy Technology Data Exchange (ETDEWEB)

    Mitchell, George [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2015-11-01

    The Roaring Fork Transit Authority (RFTA) and its VelociRFTA Bus Rapid Transit (BRT) program are unique in many ways. For example, VelociRFTA was the first rural BRT system in the United States and the operational environment of the VelociRFTA BRT is one of the most severe in the country, with extreme winter temperatures and altitudes close to 8,000 feet. RFTA viewed high altitude operation as the most challenging characteristic when it began considering the use of natural gas. RFTA is the second-largest public transit system in Colorado behind Denver's Regional Transportation District (RTD), and it is one of the largest rural public transit systems in the country. In 2013, RFTA accepted delivery of 22 new compressed natural gas (CNG) buses that went into service after completion of maintenance and refueling facilities earlier that year. This paper examines the lessons learned from RFTA's experience of investigating--and ultimately choosing--CNG for their new BRT program and focuses on the unique environment of RFTA's BRT application; the decision process to include CNG fueling in the project; unforeseen difficulties encountered in the operation of CNG buses; public perception; cost comparison to competing fuels; and considerations for indoor fueling facilities and project funding.

  3. Wind farm protection using an IEC 61850 process bus architecture

    Energy Technology Data Exchange (ETDEWEB)

    McGinn, D. [GE Digital Energy, Toronto, ON (Canada)

    2009-07-01

    This presentation discussed wind farm protection using an IEC 61850 process bus architecture. Data is transmitted via IEC 61850 messages over a fiber optic communications network to a central relaying unit (CRU) that executes protection and control (P and C) functions for a whole wind farm. The presentation also discussed the need to further simplify P and C design. Challenges of wind farm protection include physical distance; relay location; and selectivity/isolation. P and C hardware evolution was illustrated and its advantages were presented. These included one relay to set, configure, test, and maintain; eliminate the need for transfer trips; free monitoring; free disturbance recording; and easy integration of data. The development of commercially available systems began around 1990 with the IPACS system developed by Hydro One, and the SIPSUR system developed in Spain. 7 figs.

  4. Design and Analysis of Bus Front Panel Usin G FRP

    Directory of Open Access Journals (Sweden)

    G. Adinarayana

    2014-10-01

    Full Text Available Recently, Advance composite materials have taken the significant share with other engineering materials due to its mechanical properties and high strength to weight ratio. Advance composite like E-glass, S-glass, Carbon fiber, Kevlar are not yet confined at the aerospace industry but gradually these are taking over the position of other industries as well. Because of its attaining high intricacy in designing factors and as well as cheaper mould design and also less cost in production of few numbers. The applications of FRPs are spirally increasing. The aim of this project is to develop a BUS FRONT PANEL with a help of FRPs in order to sustain all the mechanical properties which are equivalent to the metals with the help of advanced computer aided software designs like ANSYS. In computer aided engineering to make the product proven in the realistic market.

  5. FAKTOR PENYEBAB KERUSAKAN SISTEM MESIN PADA BUS APTB PPD

    Directory of Open Access Journals (Sweden)

    Laela Chairani

    2015-06-01

    Full Text Available Comfort and safety of public transportation, particularly APTB PPD buses, becomes high expectations for its customers. Those expectations must be supported by the application of a good engine maintenance system. By using the method of Reliability Centered Maintenance may be determined appropriate actions to mitigate damage. From the analysis known the failures of the APTB PPD bus are malfunctions of the fuel engine, power transfer systems, difficulty to move the gear lever, and lubricating system for the rough engine noise. The cause of engine malfunction is dirty diesel filter, vehicle acceleration malfunction is due to the clutch plate wear out. Difficulty to move the gear lever indicates that the clutch slips. Rough engine noise caused by the flow of oil to the engine stalled as the result of dirty oil filter. The results of the logic tree analysis show that for each failure requires scheduling of time directed task.

  6. Characterisation of vibration input to flywheel used on urban bus

    Science.gov (United States)

    Wang, L.; Kanarachos, S.; Christensen, J.

    2016-09-01

    Vibration induced from road surface has an impact on the durability and reliability of electrical and mechanical components attached on the vehicle. There is little research published relevant to the durability assessment of a flywheel energy recovery system installed on city and district buses. Relevant international standards and legislations were reviewed and large discrepancy was found among them, in addition, there are no standards exclusively developed for kinetic energy recovery systems on vehicles. This paper describes the experimentation of assessment of road surface vibration input to the flywheel on a bus as obtained at the MIRA Proving Ground. Power density spectra have been developed based on the raw data obtained during the experimentation. Validation of this model will be carried out using accelerated life time tests that will be carried out on a shaker rig using an accumulated profile based on the theory of fatigue damage equivalence in time and frequency domain aligned with the model predictions.

  7. DESIGN OF TRANSITION TIME ADJUSTMENT TECHNIQUE FOR REDUCING BUS DELAY EFFECTS ON NOC INTERCONNECTS

    Directory of Open Access Journals (Sweden)

    MEERA K S

    2013-04-01

    Full Text Available To meet the growing computation-intensive applications the number of computing resources in single-chip has enormously increased, because current VLSI technology can support such an extensive integration of transistors. By adding many computing resources such as CPU, DSP, specific IPs, etc to build a system in System-on-Chip, its interconnection between each other becomes another challenging issue. In most System-on-Chip applications, a shared bus interconnection which needs arbitration logic to serialize several bus access requests, is adopted to communicate with each integrated processing unit because of its low-cost and simple control characteristics. However, such shared bus interconnection has some limitation in its scalability because only one master at a time can utilize the bus which means all the bus accesses should be serialized by the arbitrator. Therefore, in such an environment where the number of bus requesters is large and their required bandwidth for interconnection is more than the current bus, some other interconnection methods should be considered. Such scalable bandwidth requirement can be satisfied by using on-chip packet-switched micro-network of interconnects, generally known as Network-on-Chip (NoC architecture. It suffers however from increasingly serious interconnect crosstalk effects, which constrain the overall performance of NOC systems. In this paper some delay tolerance methods are proposed.

  8. COMPARISON OF PARALLEL AND SERIES HYBRID POWERTRAINS FOR TRANSIT BUS APPLICATION

    Energy Technology Data Exchange (ETDEWEB)

    Gao, Zhiming [ORNL; Daw, C Stuart [ORNL; Smith, David E [ORNL; Jones, Perry T [ORNL; LaClair, Tim J [ORNL; Parks, II, James E [ORNL

    2016-01-01

    The fuel economy and emissions of both conventional and hybrid buses equipped with emissions aftertreatment were evaluated via computational simulation for six representative city bus drive cycles. Both series and parallel configurations for the hybrid case were studied. The simulation results indicate that series hybrid buses have the greatest overall advantage in fuel economy. The series and parallel hybrid buses were predicted to produce similar CO and HC tailpipe emissions but were also predicted to have reduced NOx tailpipe emissions compared to the conventional bus in higher speed cycles. For the New York bus cycle (NYBC), which has the lowest average speed among the cycles evaluated, the series bus tailpipe emissions were somewhat higher than they were for the conventional bus, while the parallel hybrid bus had significantly lower tailpipe emissions. All three bus powertrains were found to require periodic active DPF regeneration to maintain PM control. Plug-in operation of series hybrid buses appears to offer significant fuel economy benefits and is easily employed due to the relatively large battery capacity that is typical of the series hybrid configuration.

  9. Air flow through a non-airconditioned bus with open windows

    Indian Academy of Sciences (India)

    S R Kale; S V Veeravalli; H D Punekar; M M Yelmule

    2007-08-01

    Open window buses without air-conditioning are a major mode of urban and inter-city transport in most countries. High occupancy combined with hot and humid conditions makes travel in these buses quite uncomfortable. In this study air flow through a bus has been studied that could be the basis for low cost and ecofriendly methods of increasing passenger comfort and possibly reduce drag. The aerodynamics of such a road vehicle has not been studied as previous investigations have been confined to vehicles with closed windows that present a smooth exterior to air flow. Using a 1:25 scaled Perspex model of an urban bus in Delhi, flow visualization was performed in a water channel. The Reynolds numbers were onetenth of a real bus moving at $10 m/s$. Smoke and tuft visualizations were also performed on an urban bus at 40 km/h. Numerical simulations were performed at the actual Reynolds number. Even though there were Reynolds number differences, the broad features were similar. Air enters the bus from the rear windows, moves to the front (relative to the bus) and exits from the front windows. Inside air velocity relative to the bus is about one-tenth of the free-stream velocity. The flow is highly three-dimensional and unsteady.

  10. Ursodeoxycholic acid suppresses mitochondria-dependent programmed cell death induced by sodium nitroprusside in SH-SY5Y cells

    International Nuclear Information System (INIS)

    Although ursodeoxycholic acid (UDCA) and its highly water-soluble formula (Yoo's solution; YS) have been shown to prevent neuronal damage, the effects of UDCA or YS against Parkinson's disease (PD)-related dopaminergic cell death has not been studied. This study investigated the protective effects of UDCA and YS on sodium nitroprusside (SNP)-induced cytotoxicity in human dopaminergic SH-SY5Y cells. Both UDCA (50–200 μM) and YS (100–200 μM) dose-dependently prevented SNP (1 mM)-induced cell death. Results showed that both UDCA and YS effectively attenuated the production of total reactive oxygen species (ROS), peroxynitrite (ONOO−) and nitric oxide (NO), and markedly inhibited the mitochondrial membrane potential (MMP) loss and intracellular reduced glutathione (GSH) depletion. SNP-induced programmed cell death events, such as nuclear fragmentation, caspase-3/7 and -9 activation, Bcl-2/Bax ratio decrease, and cytochrome c release, were significantly attenuated by both UDCA and YS. Furthermore, selective inhibitor of phosphatidylinositiol-3-kinase (PI3K), LY294002, and Akt/PKB inhibitor, triciribine, reversed the preventive effects of UDCA on the SNP-induced cytotoxicity and Bax translocation. These results suggest that UDCA can protect SH-SY5Y cells under programmed cell death process by regulating PI3K-Akt/PKB pathways.

  11. Autonomous Navigation and Obstacle Avoidance of a Micro-bus

    Directory of Open Access Journals (Sweden)

    Carlos Fernández

    2013-04-01

    Full Text Available At present, the topic of automated vehicles is one of the most promising research areas in the field of Intelligent Transportation Systems (ITS. The use of automated vehicles for public transportation also contributes to reductions in congestion levels and to improvements in traffic flow. Moreover, electrical public autonomous vehicles are environmentally friendly, provide better air quality and contribute to energy conservation. The driverless public transportation systems, which are at present operating in some airports and train stations, are restricted to dedicated roads and exhibit serious trouble dynamically avoiding obstacles in the trajectory. In this paper, an electric autonomous mini-bus is presented. All datasets used in this article were collected during the experiments carried out in the demonstration event of the 2012 IEEE Intelligent Vehicles Symposium that took place in Alcalá de Henares (Spain. The demonstration consisted of a route 725 metres long containing a list of latitude-longitude points (waypoints. The mini-bus was capable of driving autonomously from one waypoint to another using a GPS sensor. Furthermore, the vehicle is provided with a multi-beam Laser Imaging Detection and Ranging (LIDAR sensor for surrounding reconstruction and obstacle detection. When an obstacle is detected in the planned path, the planned route is modified in order to avoid the obstacle and continue its way to the end of the mission. On the demonstration day, a total of 196 attendees had the opportunity to get a ride on the vehicles. A total of 28 laps were successfully completed in full autonomous mode in a private circuit located in the National Institute for Aerospace Research (INTA, Spain. In other words, the system completed 20.3 km of driverless navigation and obstacle avoidance.

  12. Entangling a Series of Trapped Ions by Moving Cavity Bus

    Institute of Scientific and Technical Information of China (English)

    ZHANG Miao; JIA Huan-Yu; WEI Lian-Fu

    2011-01-01

    Entangling multiple qubits is one of the central tasks of quantum information processing. We propose an approach to entangle a number of cold ions (individually trapped in a string of microtraps) by a moved cavity. The cavity is pushed to include the ions one by one with a uniform velocity and thus the information stored in former ions could be transferred to the latter ones by such a moving cavity bus. Since the positions of the trapped ions are precisely located, the strengths and durations of the ion-cavity interactions can be exactly controlled. As a consequence, by properly setting the relevant parameters, typical multi-ion entangled states, e.g., W state for 10 ions, could be deterministically generated. The feasibility of the proposal is also discussed.%@@ Entangling multiple qubits is one of the central tasks of quantum information processing.We propose an approach to entangle a number of cold ions (individually trapped in a string of microtraps) by a moved cavity.The cavity is pushed to include the ions one by one with a uniform velocity and thus the information stored in former ions could be transferred to the latter ones by such a moving cavity bus.Since the positions of the trapped ions are precisely located, the strengths and durations of the ion-cavity interactions can be exactly controlled.As a consequence, by properly setting the relevant parameters, typical multi-ion entangled states, e.g., W state for 10 ions, could be deterministically generated.The feasibility of the proposal is also discussed.

  13. Alkaloids Induce Programmed Cell Death in Bloodstream Forms of Trypanosomes (Trypanosoma b. brucei)

    OpenAIRE

    Michael Wink; Vera Rosenkranz

    2008-01-01

    The potential induction of a programmed cell death (PCD) in Trypanosoma b. brucei by 55 alkaloids of the quinoline, quinolizidine, isoquinoline, indole, terpene, tropane, steroid, and piperidine type was studied by measuring DNA fragmentation and changes in mitochondrial membrane potential. For comparison, the induction of apoptosis by the same alkaloids in human leukemia cells (Jurkat APO-S) was tested. Several alkaloids of the isoquinoline, quinoline, indole and steroidal type (berberine, c...

  14. Islet Cell Response to High Fat Programming in Neonate, Weanling and Adolescent Wistar Rats

    OpenAIRE

    Cerf, Marlon E.; Johan Louw

    2014-01-01

    Context High fat programming, by exposure to a high saturated fat diet during fetal and/or lactational life induces metabolic derangements and alters islet cell architecture in neonate and weanling rats. Objective The present study assessed metabolic hanges and islet cell dynamics in response to high fat maintenance during specific developmental periods in adolescent rats, with some parameters also studied in neonate and weanling rats. Methods The experimental groups comprised neonates, weanl...

  15. Combination of ionising irradiation and hyperthermia activates programmed apoptotic and necrotic cell death pathways in human colorectal carcinoma cells

    Energy Technology Data Exchange (ETDEWEB)

    Mantel, Frederick; Frey, Benjamin; Haslinger, Stefan [Erlangen-Nuernberg Univ., University Hospital Erlangen (DE). Dept. of Radiation Oncology] (and others)

    2010-11-15

    The malignancy of tumor cells can be attenuated by interfering with cell death pathways. Since hyperthermia (HT) is a very potent radiosensitizer, the influence of HT (41.5 C for 1 hour) alone and in combination with ionising irradiation (X-ray; 5 Gy or 10 Gy) on the form of cell death as well as on the expression of proteins known to be major components in tumor cells' apoptotic and necrotic pathways were examined in colorectal tumor cells. The expression of proteins was analysed by western blot and the relative activity of caspases-3/7 by fluorescence- based assay. Colony formation was analysed using the clonogenic assay and cell death was determined with annexin V-FITC/propidium iodide staining. Combining X-ray with HT led to similar activation of caspase-3/7 and p53 expression in comparison to irradiation only while the amount of the pro-apoptotic proteins PUMA and Bax was increased in HCT15 and SW480 cells. HT alone or combinations with X-ray further resulted in a temporarily increased level of the anti-apoptotic protein Bcl-2. Irradiation plus HT further led to an up-regulation of IRF-5. The levels of RIP-1, a marker for programmed necrosis, increased in tumor cells which were treated with HT and/or X-ray. Combining 5 Gy irradiation with HT compared to irradiation resulted in a significantly increased number of necrotic tumor cells and in decreased colony formation. The combined treatment of colorectal tumor cells with X-ray and HT activates distinct tumor cell pathways and fosters the early appearance of a necrotic tumor cell phenotype. (orig.)

  16. A Mathematical Programming Model for Cell Formation Problem with Machine Replication

    Directory of Open Access Journals (Sweden)

    Reza Raminfar

    2013-01-01

    Full Text Available Cell formation (CF is a crucial aspect in the design of cellular manufacturing (CM systems. This paper develops a comprehensive mathematical programming model for the cell formation problem, where product demands, cell size limits, sequence of operations, multiple units of identical machines, machine capacity, or machine cost are all considered. In this model, the intercell moves are restricted to be unidirectional from one cell to the downstream cells, without backtracking. The proposed model is investigated through several numerical examples. To evaluate the solution quality of the proposed model, it is compared with some well-known cell formation methods from the literature, by using group capability index (GCI as a performance measure. The results and comparisons indicate that the proposed model produces solution with a higher performance.

  17. Application of the comet assay in studies of programmed cell death (PCD in plants

    Directory of Open Access Journals (Sweden)

    Maria Charzyńska

    2014-02-01

    Full Text Available Programmed cell death (PCD in plants is an intensively investigated process. One of the main characteristics of PCD in both animal and plant organisms is the non-random, internucleosomal fragmentation of nuclear DNA, usually analysed using total DNA gel electrophoresis or TUNEL method. In this paper we present application of the "comet assay" (Single Cell Gel Electrophoresis for detection of nDNA degradation in studies of PCD during plant life cycle. We analyzed three types of tissue: anther tapetum, endosperm and mesophyll which were prepared in different ways to obtain a suspension of viable cells (without cell walls. The comet assay gives a possibility of examination of the nDNA degradation in individual cell. This method is significant for studies of the plant tissue differentiation and senescence especially in the cases when it is not possible to isolate large number of cells at the same developmental stage.

  18. Re-programming tumour cell metabolism to treat cancer: no lone target for lonidamine

    Science.gov (United States)

    Bhutia, Yangzom D.; Babu, Ellappan; Ganapathy, Vadivel

    2016-01-01

    Tumour cell metabolism is very different from normal cell metabolism; cancer cells re-programme the metabolic pathways that occur in normal cells in such a manner that it optimizes their proliferation, growth and survival. Although this metabolic re-programming obviously operates to the advantage of the tumour, it also offers unique opportunities for effective cancer therapy. Molecules that target the tumour cell-specific metabolic pathways have potential as novel anti-cancer drugs. Lonidamine belongs to this group of molecules and is already in use in some countries for cancer treatment. It has been known for a long time that lonidamine interferes with energy production in tumour cells by inhibiting hexokinase II (HKII), a glycolytic enzyme. However, subsequent studies have uncovered additional pharmacological targets for the drug, which include the electron transport chain and the mitochondrial permeability transition pore, thus expanding the pharmacological effects of the drug on tumour cell metabolism. A study by Nancolas et al. in a recent issue of the Biochemical Journal identifies two additional new targets for lonidamine: the pyruvate transporter in the mitochondria and the H+-coupled monocarboxylate transporters in the plasma membrane (PM). It is thus becoming increasingly apparent that the anti-cancer effects of lonidamine do not occur through a single target; the drug works at multiple sites. Irrespective of the molecular targets, what lonidamine does in the end is to undo what the tumour cells have done in terms of re-programming cellular metabolism and mitochondrial function. PMID:27234586

  19. On the road : non-fossil fuel deployment for the public bus fleet of Sweden

    OpenAIRE

    Xylia, Maria; Silveira, Semida

    2015-01-01

    The public transport sector in Sweden has set a target to run 90% of its total vehicle-kilometers on renewable fuels by 2020, and double its market share in the long term. The focus of this paper is the adoption of renewable fuels in public bus fleets. Data for all 21 Swedish counties were gathered and analyzed, mapping the bus fleets’ condition in relation to renewable fuel deployment, CO2 emissions and energy efficiency. The main factors affecting fuel choices in the bus fleets were investi...

  20. Design of the HEAO main bus shunt regulator. [High Energy Astronomical Observatory solar array

    Science.gov (United States)

    Middlebrook, R. D.; Kimble, S. G.

    1976-01-01

    The High Energy Astronomy Observatory (HEAO) is being built for NASA by an American company. The general requirements concerning the HEAO main bus regulator are examined. The bus regulated voltage is 33 V, the maximum shunt current is 45 A, and the regulator output impedance is to be less than 0.5 Ohm from dc to 100 kHz. Loop gain design considerations for the main bus regulator are discussed and a description is given of the general device configuration. Attention is also given to regulator loop design and performance.