Technical analysis as a tool of market timing

International Nuclear Information System (INIS)

Rafferty, J.

2002-01-01

Risk management teams carry a high burden because businesses have to compete on a global scale. Timing is everything, once a decision to hedge in the futures has been made. How to determine when it is a good time to buy or sell, and be certain that this information has not already been factored into the price is tricky. There are two schools: fundamental analysis and technical analysis. Statistics and supply and demand data are examined to determine why in fundamental analysis, while technical analysis determines when by interpreting charts. With the help of charts that were displayed, the author examined the price of crude oil in 1990 and 1991 in an attempt to demonstrate technical analysis. Technical analysis is based on mathematics, but it is more art than science. It looks at market patterns that repeat themselves endlessly. Markets almost always enter into a period of consolidation or distribution when they break out. Additional charts displaying the price of crude oil for various periods from 1986 to 1991 were presented and analysed. The author concluded by stating that technical analysis provides visual guidelines to hedgers and traders to assist them in making intelligent forecasts about price and risk. figs

Forex markets: technical analysis and algorithmic trading

OpenAIRE

Klepić, Igor

2013-01-01

Technical analysis is an efficient way for analysing financial markets such as forex where currencies are being traded. Forex market is the biggest market among all of them which is closed only during weekends. Analysis uses past behaviour of the market and with different mathematical methods tries to predict the future movement of the market. With the help of technical analysis forex market allows individuals as well as large financial corporations to efficiently manage their wealth while th...

COMPARATIVE ANALYSIS BETWEEN THE FUNDAMENTAL AND TECHNICAL ANALYSIS OF STOCKS

Directory of Open Access Journals (Sweden)

Nada Petrusheva

2016-04-01

Full Text Available In the world of investing and trading, in order to have a definite advantage and constantly create profit, you need to have a strategic approach. Generally speaking, the two main schools of thought and strategies in financial markets are fundamental and technical analysis. Fundamental and technical analysis differ in several aspects, such as the way of functioning and execution, the time horizon used, the tools used and their objective. These differences lead to certain advantages and disadvantages of each of the analyses. Fundamental and technical analysis are also a subject of critical reviews by the academic and scientific community and many of these reviews concern the methods of their application, i.e. the possibility of combining the two analyses and using them complementarily to fully utilize their strengths and advantages.

Economic Analysis of Factors Affecting Technical Efficiency of ...

African Journals Online (AJOL)

Economic Analysis of Factors Affecting Technical Efficiency of Smallholders ... socio-economic characteristics which influence technical efficiency in maize production. ... Ministry of Agriculture and livestock, records, books, reports and internet.

Polar source analysis : technical memorandum

Science.gov (United States)

2017-09-29

The following technical memorandum describes the development, testing and analysis of various polar source data sets. The memorandum also includes recommendation for potential inclusion in future releases of AEDT. This memorandum is the final deliver...

ITER technical meeting on nuclear analysis

International Nuclear Information System (INIS)

Khripunov, V.

2000-01-01

The ITER technical meeting on nuclear analysis was organized on 24-25 February 2000 at the ITER Joint Work Site in Garching. It was clear from the meeting that continuous nuclear analysis is a fundamental part of the design process

Linnorm: improved statistical analysis for single cell RNA-seq expression data.

Science.gov (United States)

Yip, Shun H; Wang, Panwen; Kocher, Jean-Pierre A; Sham, Pak Chung; Wang, Junwen

2017-12-15

Linnorm is a novel normalization and transformation method for the analysis of single cell RNA sequencing (scRNA-seq) data. Linnorm is developed to remove technical noises and simultaneously preserve biological variations in scRNA-seq data, such that existing statistical methods can be improved. Using real scRNA-seq data, we compared Linnorm with existing normalization methods, including NODES, SAMstrt, SCnorm, scran, DESeq and TMM. Linnorm shows advantages in speed, technical noise removal and preservation of cell heterogeneity, which can improve existing methods in the discovery of novel subtypes, pseudo-temporal ordering of cells, clustering analysis, etc. Linnorm also performs better than existing DEG analysis methods, including BASiCS, NODES, SAMstrt, Seurat and DESeq2, in false positive rate control and accuracy. © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

Formal modelling and analysis of socio-technical systems

DEFF Research Database (Denmark)

Probst, Christian W.; Kammüller, Florian; Hansen, Rene Rydhof

2016-01-01

systems are still mostly identified through brainstorming of experts. In this work we discuss several approaches to formalising socio-technical systems and their analysis. Starting from a flow logic-based analysis of the insider threat, we discuss how to include the socio aspects explicitly, and show......Attacks on systems and organisations increasingly exploit human actors, for example through social engineering. This non-technical aspect of attacks complicates their formal treatment and automatic identification. Formalisation of human behaviour is difficult at best, and attacks on socio-technical...... a formalisation that proves properties of this formalisation. On the formal side, our work closes the gap between formal and informal approaches to socio-technical systems. On the informal side, we show how to steal a birthday cake from a bakery by social engineering....

Computer-aided System of Semantic Text Analysis of a Technical Specification

OpenAIRE

Zaboleeva-Zotova, Alla; Orlova, Yulia

2008-01-01

The given work is devoted to development of the computer-aided system of semantic text analysis of a technical specification. The purpose of this work is to increase efficiency of software engineering based on automation of semantic text analysis of a technical specification. In work it is offered and investigated the model of the analysis of the text of the technical project is submitted, the attribute grammar of a technical specification, intended for formalization of limited Ru...

DIY Solar Market Analysis Webinar Series: Solar Resource and Technical

Science.gov (United States)

Series: Solar Resource and Technical Potential DIY Solar Market Analysis Webinar Series: Solar Resource and Technical Potential Wednesday, June 11, 2014 As part of a Do-It-Yourself Solar Market Analysis Potential | State, Local, and Tribal Governments | NREL DIY Solar Market Analysis Webinar

Feasibility of commercial space manufacturing, production of pharmaceuticals. Volume 2: Technical analysis

Science.gov (United States)

1978-01-01

A technical analysis on the feasibility of commercial manufacturing of pharmaceuticals in space is presented. The method of obtaining pharmaceutical company involvement, laboratory results of the separation of serum proteins by the continuous flow electrophoresis process, the selection and study of candidate products, and their production requirements is described. The candidate products are antihemophilic factor, beta cells, erythropoietin, epidermal growth factor, alpha-1-antitrypsin and interferon. Production mass balances for antihemophelic factor, beta cells, and erythropoietin were compared for space versus ground operation. A conceptual description of a multiproduct processing system for space operation is discussed. Production requirements for epidermal growth factor of alpha-1-antitrypsin and interferon are presented.

Platforms for Single-Cell Collection and Analysis

Directory of Open Access Journals (Sweden)

Lukas Valihrach

2018-03-01

Full Text Available Single-cell analysis has become an established method to study cell heterogeneity and for rare cell characterization. Despite the high cost and technical constraints, applications are increasing every year in all fields of biology. Following the trend, there is a tremendous development of tools for single-cell analysis, especially in the RNA sequencing field. Every improvement increases sensitivity and throughput. Collecting a large amount of data also stimulates the development of new approaches for bioinformatic analysis and interpretation. However, the essential requirement for any analysis is the collection of single cells of high quality. The single-cell isolation must be fast, effective, and gentle to maintain the native expression profiles. Classical methods for single-cell isolation are micromanipulation, microdissection, and fluorescence-activated cell sorting (FACS. In the last decade several new and highly efficient approaches have been developed, which not just supplement but may fully replace the traditional ones. These new techniques are based on microfluidic chips, droplets, micro-well plates, and automatic collection of cells using capillaries, magnets, an electric field, or a punching probe. In this review we summarize the current methods and developments in this field. We discuss the advantages of the different commercially available platforms and their applicability, and also provide remarks on future developments.

Platforms for Single-Cell Collection and Analysis.

Science.gov (United States)

Valihrach, Lukas; Androvic, Peter; Kubista, Mikael

2018-03-11

Single-cell analysis has become an established method to study cell heterogeneity and for rare cell characterization. Despite the high cost and technical constraints, applications are increasing every year in all fields of biology. Following the trend, there is a tremendous development of tools for single-cell analysis, especially in the RNA sequencing field. Every improvement increases sensitivity and throughput. Collecting a large amount of data also stimulates the development of new approaches for bioinformatic analysis and interpretation. However, the essential requirement for any analysis is the collection of single cells of high quality. The single-cell isolation must be fast, effective, and gentle to maintain the native expression profiles. Classical methods for single-cell isolation are micromanipulation, microdissection, and fluorescence-activated cell sorting (FACS). In the last decade several new and highly efficient approaches have been developed, which not just supplement but may fully replace the traditional ones. These new techniques are based on microfluidic chips, droplets, micro-well plates, and automatic collection of cells using capillaries, magnets, an electric field, or a punching probe. In this review we summarize the current methods and developments in this field. We discuss the advantages of the different commercially available platforms and their applicability, and also provide remarks on future developments.

Multidirectional analysis of technical efficiency for pig production systems

DEFF Research Database (Denmark)

Labajavo, Katarina; Hansson, Helena; Asmild, Mette

2016-01-01

Declining profitability and ongoing structural changes in the pig sector require thorough efficiency analysis of individual production factors. In this study we calculated technical efficiency indices for each input and output using multidirectional efficiency analysis and examined the relationship...... between ‘farm-specific characteristics’ and input and output technical efficiencies by production type (piglet, growing-finishing, finish-to-farrow). The results indicated that advisory services and farm location were not significantly correlated with technical efficiency. Similar results were obtained...... for ‘housing practices’, with the exception of the latest technology such as heated floors in relation to input labour technical efficiency for growing-finishing and finish-to-farrow productions. Use of written instructions for feeding for growing-finishing and finish-to-farrow production and written...

Methylation analysis of polysaccharides: Technical advice.

Science.gov (United States)

Sims, Ian M; Carnachan, Susan M; Bell, Tracey J; Hinkley, Simon F R

2018-05-15

Glycosyl linkage (methylation) analysis is used widely for the structural determination of oligo- and poly-saccharides. The procedure involves derivatisation of the individual component sugars of a polysaccharide to partially methylated alditol acetates which are analysed and quantified by gas chromatography-mass spectrometry. The linkage positions for each component sugar can be determined by correctly identifying the partially methylated alditol acetates. Although the methods are well established, there are many technical aspects to this procedure and both careful attention to detail and considerable experience are required to achieve a successful methylation analysis and to correctly interpret the data generated. The aim of this article is to provide the technical details and critical procedural steps necessary for a successful methylation analysis and to assist researchers (a) with interpreting data correctly and (b) in providing the comprehensive data required for reviewers to fully assess the work. Copyright © 2018 Elsevier Ltd. All rights reserved.

Single cell analysis contemporary research and clinical applications

CERN Document Server

Cossarizza, Andrea

2017-01-01

This book highlights the current state of the art in single cell analysis, an area that involves many fields of science – from clinical hematology, functional analysis and drug screening, to platelet and microparticle analysis, marine biology and fundamental cancer research. This book brings together an eclectic group of current applications, all of which have a significant impact on our current state of knowledge. The authors of these chapters are all pioneering researchers in the field of single cell analysis. The book will not only appeal to those readers more focused on clinical applications, but also those interested in highly technical aspects of the technologies. All of the technologies identified utilize unique applications of photon detection systems.

TECHNICAL EFFICIENCY AND TECHNICAL LEVEL INDICATORS APPLICATION FOR CIVIL AIRCRAFT FUNCTIONAL PROPERTIES ANALYSIS

Directory of Open Access Journals (Sweden)

Vadim V. Efimov

2018-01-01

Full Text Available Functional properties characterize the purpose of the aircraft and are described by its flight performance characteristics such as range and cruising speed, payload, runway characteristics, etc. Functional properties also characterize the aircraft efficiency that determines the objective need for their analysis by both aircraft designers and operators in conditions of permanent and systematic efficiency increase necessity. When choosing the aircraft, it is important for the operator to make sure that a selected aircraft type has a high level of functional properties, which will allow it to provide high operational efficiency without obsolescence in the long term. However, when choosing from several aircraft types the operator has to face the fact that some characteristics of considered aircraft variants are better and the others are worse that does not allow to definitely determine what aircraft type has a higher level of functional properties.The possibility of applying technical efficiency indicators and a generalized technical level indicator for analyzing the functional properties of civil aviation aircraft is explored in this article. Fuel, weight and target efficiency values as well as the previously improved technical level indicator value were calculated for the different generations and modifications of Boeing 737 and Airbus A320 families of medium-range airplanes, which was followed by the results interpretation within one airplane generation and when moving historically from one airplane generation to another. According to analysis results it is concluded that it is impossible to define the change of the aircraft functional properties level by the change in the values of separate technical efficiency indicators. Thus, it is proposed to use a generalized technical level indicator that determines the level of aircraft technical perfection for purpose and to use efficiency indicators to analyze the cost of providing this level of

Methodology for risk-based analysis of technical specifications

International Nuclear Information System (INIS)

Vesely, W.E.; Gaertner, J.P.; Wagner, D.P.

1985-01-01

Part of the effort by EPRI to apply probabilistic risk assessment methods and results to the solution of utility problems involves the investigation of methods for risk-based analysis of technical specifications. The culmination of this investigation is the SOCRATES computer code developed by Battelle's Columbus Laboratories to assist in the evaluation of technical specifications of nuclear power plants. The program is designed to use information found in PRAs to re-evaluate risk for changes in component allowed outage times (AOTs) and surveillance test intervals (STIs). The SOCRATES program is a unique and important tool for technical specification evaluations. The detailed component unavailability model allows a detailed analysis of AOT and STI contributions to risk. Explicit equations allow fast and inexpensive calculations. Because the code is designed to accept ranges of parameters and to save results of calculations that do not change during the analysis, sensitivity studies are efficiently performed and results are clearly displayed

77 FR 65542 - Hydrogen and Fuel Cell Technical Advisory Committee (HTAC)

Science.gov (United States)

2012-10-29

... DEPARTMENT OF ENERGY Office of Energy Efficiency and Renewable Energy Hydrogen and Fuel Cell... Energy. ACTION: Notice of Open Meeting. SUMMARY: The Hydrogen and Fuel Cell Technical Advisory Committee... Agenda: (updates will be posted on the web at: http://hydrogen.energy.gov ). Public Comment DOE Program...

75 FR 2860 - Hydrogen and Fuel Cell Technical Advisory Committee (HTAC)

Science.gov (United States)

2010-01-19

... DEPARTMENT OF ENERGY Office of Energy Efficiency and Renewable Energy Hydrogen and Fuel Cell... Energy. ACTION: Notice of Open Meeting. SUMMARY: The Hydrogen and Fuel Cell Technical Advisory Committee... change; updates will be posted on http://hydrogen.energy.gov and copies of the final agenda will...

Technical Challenges in the Derivation of Human Pluripotent Cells

Directory of Open Access Journals (Sweden)

Parinya Noisa

2011-01-01

Full Text Available It has long been discovered that human pluripotent cells could be isolated from the blastocyst state of embryos and called human embryonic stem cells (ESCs. These cells can be adapted and propagated indefinitely in culture in an undifferentiated manner as well as differentiated into cell representing the three major germ layers: endoderm, mesoderm, and ectoderm. However, the derivation of human pluripotent cells from donated embryos is limited and restricted by ethical concerns. Therefore, various approaches have been explored and proved their success. Human pluripotent cells can also be derived experimentally by the nuclear reprogramming of somatic cells. These techniques include somatic cell nuclear transfer (SCNT, cell fusion and overexpression of pluripotent genes. In this paper, we discuss the technical challenges of these approaches for nuclear reprogramming, involving their advantages and limitations. We will also highlight the possible applications of these techniques in the study of stem cell biology.

78 FR 27235 - Technical Guidance for Assessing Environmental Justice in Regulatory Analysis

Science.gov (United States)

2013-05-09

... Justice in Regulatory Analysis.'' The purpose of this guidance is to provide EPA analysts with technical...-566-2363. Mail: Technical Guidance for Assessing Environmental Justice in Regulatory Analysis... ENVIRONMENTAL PROTECTION AGENCY [EPA-HQ-OA-2013-0320; FRL-9810-5] Technical Guidance for Assessing...

Persistent profitability of technical analysis on foreign exchange markets?

OpenAIRE

L. MENKHOFF; M. SCHLUMBERGER

1995-01-01

The effect of technical analyses on the performance of subsequent policies and actions in the foreign exchange markets is analysed using three cases. Results show that use of technical analyses is persistently profitable. Participants, however, tend to view short-term market risk as important and thus decide to forego some of the rules derived from technical analysis. This observation does not negate the theory on efficient learning.

Optimized multiparametric flow cytometric analysis of circulating endothelial cells and their subpopulations in peripheral blood of patients with solid tumors: a technical analysis

Directory of Open Access Journals (Sweden)

Zhou F

2018-03-01

with solid tumors. Several key technical issues regarding preanalytical elements, FCM data acquisition, and analysis were addressed. Furthermore, we clinically validated the utility of our method. The baseline levels of mature CECs, endothelial progenitor cells, and activated CECs were higher in cancer patients than healthy subjects (P<0.01. However, there was no significant difference in resting CEC levels between healthy subjects and cancer patients (P=0.193.Conclusion: We integrated and comprehensively addressed significant technical issues found in previously published assays and validated the reproducibility and sensitivity of our proposed method. Future work is required to explore the potential of our optimized method in clinical oncologic applications. Keywords: circulating endothelial cells, CECs, CEC subpopulations, flow cytometry, methods

An Intelligent technical analysis using neural network

Directory of Open Access Journals (Sweden)

Reza Raei

2011-07-01

Full Text Available Technical analysis has been one of the most popular methods for stock market predictions for the past few decades. There have been enormous technical analysis methods to study the behavior of stock market for different kinds of trading markets such as currency, commodity or stock. In this paper, we propose two different methods based on volume adjusted moving average and ease of movement for stock trading. These methods are used with and without generalized regression neural network methods and the results are compared with each other. The preliminary results on historical stock price of 20 firms indicate that there is no meaningful difference between various proposed models of this paper.

Technical Analysis in Foreign Exchange - The Workhorse Gains Further Ground

OpenAIRE

Gehrig, Thomas; Menkhoff, Lukas

2003-01-01

This work extends earlier survey studies on the use of technical analysis by considering flow analysis as a third form of information production. Moreover the survey covers FX dealers and also the rising fund managers. Technical analysis has gained importance over time and is now the most equally spread kind of analysis. It has by far the greatest importance in FX dealing and is second in fund management. Charts are used for shorter-term forecasting horizons while flows dominate at the shorte...

Computer Support of Semantic Text Analysis of a Technical Specification on Designing Software

OpenAIRE

Zaboleeva-Zotova, Alla; Orlova, Yulia

2009-01-01

The given work is devoted to development of the computer-aided system of semantic text analysis of a technical specification. The purpose of this work is to increase efficiency of software engineering based on automation of semantic text analysis of a technical specification. In work it is offered and investigated a technique of the text analysis of a technical specification is submitted, the expanded fuzzy attribute grammar of a technical specification, intended for formaliza...

Characterization of technical surfaces by structure function analysis

Science.gov (United States)

Kalms, Michael; Kreis, Thomas; Bergmann, Ralf B.

2018-03-01

The structure function is a tool for characterizing technical surfaces that exhibits a number of advantages over Fourierbased analysis methods. So it is optimally suited for analyzing the height distributions of surfaces measured by full-field non-contacting methods. The structure function is thus a useful method to extract global or local criteria like e. g. periodicities, waviness, lay, or roughness to analyze and evaluate technical surfaces. After the definition of line- and area-structure function and offering effective procedures for their calculation this paper presents examples using simulated and measured data of technical surfaces including aircraft parts.

Quantitative high-resolution genomic analysis of single cancer cells.

Science.gov (United States)

Hannemann, Juliane; Meyer-Staeckling, Sönke; Kemming, Dirk; Alpers, Iris; Joosse, Simon A; Pospisil, Heike; Kurtz, Stefan; Görndt, Jennifer; Püschel, Klaus; Riethdorf, Sabine; Pantel, Klaus; Brandt, Burkhard

2011-01-01

During cancer progression, specific genomic aberrations arise that can determine the scope of the disease and can be used as predictive or prognostic markers. The detection of specific gene amplifications or deletions in single blood-borne or disseminated tumour cells that may give rise to the development of metastases is of great clinical interest but technically challenging. In this study, we present a method for quantitative high-resolution genomic analysis of single cells. Cells were isolated under permanent microscopic control followed by high-fidelity whole genome amplification and subsequent analyses by fine tiling array-CGH and qPCR. The assay was applied to single breast cancer cells to analyze the chromosomal region centred by the therapeutical relevant EGFR gene. This method allows precise quantitative analysis of copy number variations in single cell diagnostics.

Analysis of Technical Efficiency of Small Holder Maize Growing ...

African Journals Online (AJOL)

The objective of this study was to examine the level of technical efficiency of smallholder maize producers and identify its determinants in Horo Guduru Wollega zone of Oromia Regional State, Ethiopia. A Cobb-Douglass stochastic production function model was used for the analysis. To specify technical inefficiency effects ...

77 FR 47501 - Applications for New Awards; Technical Assistance on State Data Collection, Analysis, and...

Science.gov (United States)

2012-08-08

... Awards; Technical Assistance on State Data Collection, Analysis, and Reporting--National IDEA Technical... for New Awards; Technical Assistance on State Data Collection, Analysis, and Reporting--National IDEA... Assistance on State Data Collection, Analysis, and Reporting--National IDEA Technical Assistance Center on...

Vehicle Systems Analysis Technical Team Roadmap

Energy Technology Data Exchange (ETDEWEB)

None

2013-06-01

The mission of the Vehicle Systems Analysis Technical Team (VSATT) is to evaluate the performance and interactions of proposed advanced automotive powertrain components and subsystems, in a vehicle systems context, to inform ongoing research and development activities and maximize the potential for fuel efficiency improvements and emission reduction.

Analysis Of Natural Zeolites For Technical Nuclear

International Nuclear Information System (INIS)

Sarria, P.; Desdin, L.; Dominguez, O.

1999-01-01

In this article a methodology of elementary analysis of natural zeolites is reported using different technical nuclear (AANR, FRX, MRN and EG). Determines the elementary composition of ours of two Cuban locations. (Author) [es

Poisson-event-based analysis of cell proliferation.

Science.gov (United States)

Summers, Huw D; Wills, John W; Brown, M Rowan; Rees, Paul

2015-05-01

A protocol for the assessment of cell proliferation dynamics is presented. This is based on the measurement of cell division events and their subsequent analysis using Poisson probability statistics. Detailed analysis of proliferation dynamics in heterogeneous populations requires single cell resolution within a time series analysis and so is technically demanding to implement. Here, we show that by focusing on the events during which cells undergo division rather than directly on the cells themselves a simplified image acquisition and analysis protocol can be followed, which maintains single cell resolution and reports on the key metrics of cell proliferation. The technique is demonstrated using a microscope with 1.3 μm spatial resolution to track mitotic events within A549 and BEAS-2B cell lines, over a period of up to 48 h. Automated image processing of the bright field images using standard algorithms within the ImageJ software toolkit yielded 87% accurate recording of the manually identified, temporal, and spatial positions of the mitotic event series. Analysis of the statistics of the interevent times (i.e., times between observed mitoses in a field of view) showed that cell division conformed to a nonhomogeneous Poisson process in which the rate of occurrence of mitotic events, λ exponentially increased over time and provided values of the mean inter mitotic time of 21.1 ± 1.2 hours for the A549 cells and 25.0 ± 1.1 h for the BEAS-2B cells. Comparison of the mitotic event series for the BEAS-2B cell line to that predicted by random Poisson statistics indicated that temporal synchronisation of the cell division process was occurring within 70% of the population and that this could be increased to 85% through serum starvation of the cell culture. © 2015 International Society for Advancement of Cytometry.

Quantitative high-resolution genomic analysis of single cancer cells.

Directory of Open Access Journals (Sweden)

Juliane Hannemann

Full Text Available During cancer progression, specific genomic aberrations arise that can determine the scope of the disease and can be used as predictive or prognostic markers. The detection of specific gene amplifications or deletions in single blood-borne or disseminated tumour cells that may give rise to the development of metastases is of great clinical interest but technically challenging. In this study, we present a method for quantitative high-resolution genomic analysis of single cells. Cells were isolated under permanent microscopic control followed by high-fidelity whole genome amplification and subsequent analyses by fine tiling array-CGH and qPCR. The assay was applied to single breast cancer cells to analyze the chromosomal region centred by the therapeutical relevant EGFR gene. This method allows precise quantitative analysis of copy number variations in single cell diagnostics.

Integrating technical analysis and public values in risk-based decision making

International Nuclear Information System (INIS)

Bohnenblust, Hans; Slovic, Paul

1998-01-01

Simple technical analysis cannot capture the complex scope of preferences or values of society and individuals. However, decision making needs to be sustained by formal analysis. The paper describes a policy framework which incorporates both technical analysis and aspects of public values. The framework can be used as a decision supporting tool and helps decision makers to make more informed and more transparent decisions about safety issues

Instrument and Survey Analysis Technical Report: Program Implementation Survey. Technical Report #1112

Science.gov (United States)

Alonzo, Julie; Tindal, Gerald

2011-01-01

This technical document provides guidance to educators on the creation and interpretation of survey instruments, particularly as they relate to an analysis of program implementation. Illustrative examples are drawn from a survey of educators related to the use of the easyCBM learning system. This document includes specific sections on…

Lithium-thionyl chloride cell system safety hazard analysis

Science.gov (United States)

Dampier, F. W.

1985-03-01

This system safety analysis for the lithium thionyl chloride cell is a critical review of the technical literature pertaining to cell safety and draws conclusions and makes recommendations based on this data. The thermodynamics and kinetics of the electrochemical reactions occurring during discharge are discussed with particular attention given to unstable SOCl2 reduction intermediates. Potentially hazardous reactions between the various cell components and discharge products or impurities that could occur during electrical or thermal abuse are described and the most hazardous conditions and reactions identified. Design factors influencing the safety of Li/SOCl2 cells, shipping and disposal methods and the toxicity of Li/SOCl2 battery components are additional safety issues that are also addressed.

Fuel cells for transport: can the promise be fulfilled? Technical requirements and demands from customers

Science.gov (United States)

Klaiber, Thomas

The paper discusses the technical requirements and the customer demands for vehicles that have an on-board methanol reformer and fuel cells. The research concentrates on the technical developmental risks which include minimizing volume, reducing weight and, at the same time, improving efficiency and system dynamics. Fuel cell powered vehicles with methanol reformers are not only suitable for a niche market but also these vehicles will compete with conventional vehicles. The greatest hindrance will be the price of the fuel cell. A possible progressive development of the number of fuel cell powered vehicles in conjunction with a reduction in costs will be discussed in the paper. When fuel cell vehicles come to the market it is necessary that an infrastructure for the fuel methanol or hydrogen is installed. Therefore, it will only be possible to introduce fuel cell vehicles into special markets, e.g. California. Such a process will need to be subsidized by additional incentives like tax concessions. Today there are many technical risks and unsolved problems relating to production technologies, infrastructure, and costs. Nevertheless, among the alternative power units, the fuel cell seems to be the only one that might be competitive to the conventional power unit, especially relating to emissions.

Technical analysis in the foreign exchange market: a layman's guide

OpenAIRE

Christopher J. Neely

1997-01-01

Economists have traditionally been skeptical of the value of technical analysis, the use of past price behavior to guide trading decisions in asset markets. Instead, they have relied on the logic of the efficient markets hypothesis. Christopher J. Neely briefly explains the fundamentals of technical analysis and the efficient markets hypothesis as applied to the foreign exchange market, evaluates the profitability of simple trading rules, and reviews recent ideas that might justify extrapolat...

77 FR 47495 - Final Priority; Technical Assistance on State Data Collection, Analysis, and Reporting-National...

Science.gov (United States)

2012-08-08

... Priority; Technical Assistance on State Data Collection, Analysis, and Reporting--National IDEA Technical... 34 CFR Chapter III [CFDA Number 84.373Z] Final Priority; Technical Assistance on State Data Collection, Analysis, and Reporting--National IDEA Technical Assistance Center on Early Childhood...

On the Statistical Validation of Technical Analysis

Directory of Open Access Journals (Sweden)

Rosane Riera Freire

2007-06-01

Full Text Available Technical analysis, or charting, aims on visually identifying geometrical patterns in price charts in order to antecipate price "trends". In this paper we revisit the issue of thecnical analysis validation which has been tackled in the literature without taking care for (i the presence of heterogeneity and (ii statistical dependence in the analyzed data - various agglutinated return time series from distinct financial securities. The main purpose here is to address the first cited problem by suggesting a validation methodology that also "homogenizes" the securities according to the finite dimensional probability distribution of their return series. The general steps go through the identification of the stochastic processes for the securities returns, the clustering of similar securities and, finally, the identification of presence, or absence, of informatinal content obtained from those price patterns. We illustrate the proposed methodology with a real data exercise including several securities of the global market. Our investigation shows that there is a statistically significant informational content in two out of three common patterns usually found through technical analysis, namely: triangle, rectangle and head and shoulders.

Moving Mini-Max - a new indicator for technical analysis

OpenAIRE

Z. K. Silagadze

2008-01-01

We propose a new indicator for technical analysis. The indicator emphasizes maximums and minimums in price series with inherent smoothing and has a potential to be useful in both mechanical trading rules and chart pattern analysis.

Technical requirements document for the waste flow analysis

International Nuclear Information System (INIS)

Shropshire, D.E.

1996-05-01

Purpose of this Technical Requirements Document is to define the top level customer requirements for the Waste Flow Analysis task. These requirements, once agreed upon with DOE, will be used to flow down subsequent development requirements to the model specifications. This document is intended to be a ''living document'' which will be modified over the course of the execution of this work element. Initial concurrence with the technical functional requirements from Environmental Management (EM)-50 is needed before the work plan can be developed

Analysis of "The Wonderful Desert." Technical Report No. 170.

Science.gov (United States)

Green, G. M.; And Others

This report presents a text analysis of "The Wonderful Desert," a brief selection from the "Reader's Digest Skill Builder" series. (The techniques used in arriving at the analysis are presented in a Reading Center Technical Report, Number 168, "Problems and Techniques of Text Analysis.") Tables are given for a…

Modeling technical change in climate analysis: evidence from agricultural crop damages.

Science.gov (United States)

Ahmed, Adeel; Devadason, Evelyn S; Al-Amin, Abul Quasem

2017-05-01

This study accounts for the Hicks neutral technical change in a calibrated model of climate analysis, to identify the optimum level of technical change for addressing climate changes. It demonstrates the reduction to crop damages, the costs to technical change, and the net gains for the adoption of technical change for a climate-sensitive Pakistan economy. The calibrated model assesses the net gains of technical change for the overall economy and at the agriculture-specific level. The study finds that the gains of technical change are overwhelmingly higher than the costs across the agriculture subsectors. The gains and costs following technical change differ substantially for different crops. More importantly, the study finds a cost-effective optimal level of technical change that potentially reduces crop damages to a minimum possible level. The study therefore contends that the climate policy for Pakistan should consider the role of technical change in addressing climate impacts on the agriculture sector.

Accuracy Combination Test of Classical and Modern Technical Analysis: A Case Study in Stock of PT Wijaya Karya Tbk

Directory of Open Access Journals (Sweden)

Agustini Hamid

2016-05-01

Full Text Available The research aimed to measure the accuracy and combination of Classic and Modern Technical Analysis. PT Wijaya Karya Tbk (WIKA’s stock in two periods is the sample of research. Technical analysis was used to predict stock prices by observing changes in historical share price. Practically, technical analysis is divided into Classic Technical and Modern. Research was conducted by library study and using a computer software. Microsft Excel was used for the simulation and Chart Nexus for analyzing Modern Technical Analysis. The research period started in January 1, 2013 until December 31, 2013 and January 1, 2014 until December 31, 2014. The Classic Technical Analysis used Support, Resistance, Trendline, and Flag Patern. Meanwhile for Modern Technical Analysis used Moving Average, Stochastic, Moving Average Convergence Divergence (MACD indicator. The Classical Technical Analysis gave less result than Modern Technical Analysis. The classical give 14 investment decisions in two periods. The average return of Classical Technical is 15,50%. Meanwhile the Modern Technical Analysis gave 18 investment decisions in two periods. The average return of Modern Technical is 18,14%. Combining Classic Technical Analysis and Modern Technical Analysis gave 20 investment decisions with the average rate of return 20,41%.

Case studies: Risk-based analysis of technical specifications

International Nuclear Information System (INIS)

Wagner, D.P.; Minton, L.A.; Gaertner, J.P.

1987-01-01

The SOCRATES computer program uses the results of a Probabilistic Risk Assessment (PRA) or a system level risk analysis to calculate changes in risk due to changes in the surveillance test interval and/or the allowed outage time stated in the technical specification. The computer program can accommodate various testing strategies (such as staggered or simultaneous testing) to allow modeling of component testing as it is carried out at a plant. The methods and computer program are an integral part of a larger decision process aimed at determining benefits from technical specification changes. These benefits can include cost savings to the utilities by reducing forced shutdowns with no adverse impacts on risk. Three summaries of case study applications are included to demonstrate the types of results that can be achieved through risk-based evaluation of technical specifications. (orig.)

Analysis of Technical Feasibility of Traveling Wave Reactor

International Nuclear Information System (INIS)

Kim, Sang Ji; Yoo, Jae Woon; Bae, In Ho

2011-01-01

The status and trend of TWR, patent status and its major technical characteristics were examined in this study. Main technical features of traveling wave reactor can be characterized as a reactor operation without refueling up to the reactor life more than 60 years and TWR utilizes depleted uranium which would be produced from the enrichment process as a byproduct. Enriched fuel is only loaded to an igniter which is required for initiation of burning wave. In this study, quantitative analysis of TWR arising from the technical features was carried out in terms of resource utilization, safety and integrity, and proliferation resistance. In parallel with the concept review of TerraPower SWR design concepts, independent analysis of SWR design by altering a design specification and operation strategy was done in this study. The fuel rod design of SWR was also investigated based on the current database of fuel irradiation and performance. The technical issues of TWR or SWR which should be prior to detailed research and development can be summarized as follows: ·Strong physical protection is required during the shuffling or in-service inspection period to improve the proliferation resistance. ·New flow control logic or device is required for distributing the assembly-wise flow to be corresponded with power swing of fuel assembly. ·High integrity cladding material need to be developed for covering the high fast neutron fluence more than three times of current limit which result from the high burnup and long fuel cycle. The metal fuel under the high burnup condition should be validated through the irradiation test

Comparative analysis of technical efficiencies between compound ...

African Journals Online (AJOL)

This study was designed to compare the level of technical efficiency in the compound and non compound farms in Imo state. A multi-stage random sampling technique was used to select 120 food crop farmers from two out of the three agricultural zones in Imo state. Using the Chow (1960) analysis of covariance technique ...

Stock market prediction using technical analysis

Directory of Open Access Journals (Sweden)

Bradić-Martinović Aleksandra

2006-01-01

Full Text Available Technical analysis (TA is a form of analyzing market encompassing supply and demand of securities according to the study of their prices and trading volume. Using the appropriate methods, TA aims to identify price movements in the stock market, futures or currencies. In short, TA analysis is the process by which "future price movements are formulated according to the price history". TA originates from the work of Charles Dow and his conclusions about the global behavior of the market, as well as from Elliot Wave Theory. Dow did not regard its theory as a tool for stock market movement prediction, nor as a guide for investors, but as a kind of barometer of general market movements. The term TA methods encompasses all the methods used in tracking prices aiming to clearly predict future events. Many different methods, mainly statistical, are used in technical analysis, the most popular ones being: establishing and following trends using moving average, recognizing price momentum, calculating indicators and oscillators, as well as cycle analysis (structure indicators. It is also necessary to point out that TA is not a science in the true meaning of the term, and that methods it uses frequently deviate from the conventional manner of their use. The main advantage of these methods is their relative ease of use, aiming to give as clear picture as possible of price movements, while at the same time avoiding the use of complicated and complex mathematical methods. The reason for this is simple and is reflected in the dynamics of financial markets, where changes occur during short periods of time and where prompt decision-making is of vital importance.

A rank-based algorithm of differential expression analysis for small cell line data with statistical control.

Science.gov (United States)

Li, Xiangyu; Cai, Hao; Wang, Xianlong; Ao, Lu; Guo, You; He, Jun; Gu, Yunyan; Qi, Lishuang; Guan, Qingzhou; Lin, Xu; Guo, Zheng

2017-10-13

To detect differentially expressed genes (DEGs) in small-scale cell line experiments, usually with only two or three technical replicates for each state, the commonly used statistical methods such as significance analysis of microarrays (SAM), limma and RankProd (RP) lack statistical power, while the fold change method lacks any statistical control. In this study, we demonstrated that the within-sample relative expression orderings (REOs) of gene pairs were highly stable among technical replicates of a cell line but often widely disrupted after certain treatments such like gene knockdown, gene transfection and drug treatment. Based on this finding, we customized the RankComp algorithm, previously designed for individualized differential expression analysis through REO comparison, to identify DEGs with certain statistical control for small-scale cell line data. In both simulated and real data, the new algorithm, named CellComp, exhibited high precision with much higher sensitivity than the original RankComp, SAM, limma and RP methods. Therefore, CellComp provides an efficient tool for analyzing small-scale cell line data. © The Author 2017. Published by Oxford University Press.

Contract Source Selection: An Analysis of Lowest Price Technically Acceptable and Tradeoff Strategies

Science.gov (United States)

2016-06-15

using- spss - statistics.php Lamoureux, J., Murrow, M., & Walls, C. (2015). Relationship of source selection methods to contract outcomes: an analysis ...Contract Source Selection: an Analysis of Lowest Price Technically Acceptable and Tradeoff Strategies 15 June 2016 LCDR Jamal M. Osman, USN...ACQUISITION RESEARCH PROGRAM SPONSORED REPORT SERIES Contract Source Selection: an Analysis of Lowest Price Technically Acceptable and Tradeoff

10 CFR 52.157 - Contents of applications; technical information in final safety analysis report.

Science.gov (United States)

2010-01-01

...; technical information in final safety analysis report. The application must contain a final safety analysis... 10 Energy 2 2010-01-01 2010-01-01 false Contents of applications; technical information in final safety analysis report. 52.157 Section 52.157 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES...

Benefit-Cost Analysis of Integrated Paratransit Systems : Volume 6. Technical Appendices.

Science.gov (United States)

1979-09-01

This last volume, includes five technical appendices which document the methodologies used in the benefit-cost analysis. They are the following: Scenario analysis methodology; Impact estimation; Example of impact estimation; Sensitivity analysis; Agg...

Technical efficiency of district hospitals: Evidence from Namibia using Data Envelopment Analysis

Directory of Open Access Journals (Sweden)

Mutirua Kautoo

2006-03-01

Full Text Available Abstract Background In most countries of the sub-Saharan Africa, health care needs have been increasing due to emerging and re-emerging health problems. However, the supply of health care resources to address the problems has been continuously declining, thus jeopardizing the progress towards achieving the health-related Millennium Development Goals. Namibia is no exception to this. It is therefore necessary to quantify the level of technical inefficiency in the countries so as to alert policy makers of the potential resource gains to the health system if the hospitals that absorb a lion's share of the available resources are technically efficient. Method All public sector hospitals (N = 30 were included in the study. Hospital capacity utilization ratios and the data envelopment analysis (DEA technique were used to assess technical efficiency. The DEA model used three inputs and two outputs. Data for four financial years (1997/98 to 2000/2001 was used for the analysis. To test for the robustness of the DEA technical efficiency scores the Jackknife analysis was used. Results The findings suggest the presence of substantial degree of pure technical and scale inefficiency. The average technical efficiency level during the given period was less than 75%. Less than half of the hospitals included in the study were located on the technically efficient frontier. Increasing returns to scale is observed to be the predominant form of scale inefficiency. Conclusion It is concluded that the existing level of pure technical and scale inefficiency of the district hospitals is considerably high and may negatively affect the government's initiatives to improve access to quality health care and scaling up of interventions that are necessary to achieve the health-related Millennium Development Goals. It is recommended that the inefficient hospitals learn from their efficient peers identified by the DEA model so as to improve the overall performance of the health

Selection of Belt Conveyors Drive Units Number by Technical –Economical Analysis

OpenAIRE

Despodov, Zoran; Mijalkovski, Stojance; Adjiski, Vancho; Panov, Zoran

2014-01-01

In this paper is presented a methodology for selection of belt conveyor drive units number by technical - economical analysis of their parameters. Belt Conveyors with follow drive arrangement will be considered: one, two, three and four drive units. In the technical - economical analysis are including: Tension forces, Power of belt conveyor, Costs for belt, Costs for power and reducers, Total cost for belt conveyor system.

Hydrogen as a fuel for fuel cell vehicles: A technical and economic comparison

Energy Technology Data Exchange (ETDEWEB)

Ogden, J.; Steinbugler, M.; Kreutz, T. [Princeton Univ., NJ (United States). Center for Energy and Environmental Studies

1997-12-31

All fuel cells currently being developed for near term use in vehicles require hydrogen as a fuel. Hydrogen can be stored directly or produced onboard the vehicle by reforming methanol, ethanol or hydrocarbon fuels derived from crude oil (e.g., Diesel, gasoline or middle distillates). The vehicle design is simpler with direct hydrogen storage, but requires developing a more complex refueling infrastructure. In this paper, the authors compare three leading options for fuel storage onboard fuel cell vehicles: compressed gas hydrogen storage; onboard steam reforming of methanol; onboard partial oxidation (POX) of hydrocarbon fuels derived from crude oil. Equilibrium, kinetic and heat integrated system (ASPEN) models have been developed to estimate the performance of onboard steam reforming and POX fuel processors. These results have been incorporated into a fuel cell vehicle model, allowing us to compare the vehicle performance, fuel economy, weight, and cost for various fuel storage choices and driving cycles. A range of technical and economic parameters were considered. The infrastructure requirements are also compared for gaseous hydrogen, methanol and hydrocarbon fuels from crude oil, including the added costs of fuel production, storage, distribution and refueling stations. Considering both vehicle and infrastructure issues, the authors compare hydrogen to other fuel cell vehicle fuels. Technical and economic goals for fuel cell vehicle and hydrogen technologies are discussed. Potential roles for hydrogen in the commercialization of fuel cell vehicles are sketched.

Problems about the analysis of technical requirements compliance in NPPPCI systems

International Nuclear Information System (INIS)

Perello, M.

1978-01-01

The display of the problems that the analysis of the technical requirements compliance bring along is presented. In the project of nuclear power plants, above all, the influence of national and international standards in the analysis of the adjustment of requirements established by the governments of nuclear safety of the different countries. In the oral presentation greater emphasis is made on the difficulties that the PSAR evaluation brings when the lack of technical standards in the owner country makes necessary the use of other countries rules. (author)

78 FR 39284 - Technical Guidance for Assessing Environmental Justice in Regulatory Analysis

Science.gov (United States)

2013-07-01

... ENVIRONMENTAL PROTECTION AGENCY [EPA-HQ-OA-2013-0320; FRL-9830-1] Technical Guidance for Assessing Environmental Justice in Regulatory Analysis AGENCY: Environmental Protection Agency (EPA). ACTION: Notice... Environmental Protection Agency (EPA) issued for public comment a document entitled, ``Technical Guidance for...

New approaches for the analysis of confluent cell layers with quantitative phase digital holographic microscopy

Science.gov (United States)

Pohl, L.; Kaiser, M.; Ketelhut, S.; Pereira, S.; Goycoolea, F.; Kemper, Björn

2016-03-01

Digital holographic microscopy (DHM) enables high resolution non-destructive inspection of technical surfaces and minimally-invasive label-free live cell imaging. However, the analysis of confluent cell layers represents a challenge as quantitative DHM phase images in this case do not provide sufficient information for image segmentation, determination of the cellular dry mass or calculation of the cell thickness. We present novel strategies for the analysis of confluent cell layers with quantitative DHM phase contrast utilizing a histogram based-evaluation procedure. The applicability of our approach is illustrated by quantification of drug induced cell morphology changes and it is shown that the method is capable to quantify reliable global morphology changes of confluent cell layers.

Refurbishment of Railroad Crossties : A Technical and Economic Analysis

Science.gov (United States)

1977-12-01

An analysis of the principal modes of failure for wooden railroad crossties was conducted and an evaluation of the technical and economic feasibility of refurbishing these ties was conducted. Among the principal modes of structural deterioration, onl...

10 CFR 52.79 - Contents of applications; technical information in final safety analysis report.

Science.gov (United States)

2010-01-01

...; technical information in final safety analysis report. (a) The application must contain a final safety... 10 Energy 2 2010-01-01 2010-01-01 false Contents of applications; technical information in final safety analysis report. 52.79 Section 52.79 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) LICENSES...

Can Technical Analysis Signals Detect Price Reactions Around Earnings Announcement?: Evidence from Indonesia

OpenAIRE

Dedhy Sulistiawan; Jogiyanto Hartono

2014-01-01

This study examines whether technical analysis signals can detect price reactions before and after earnings announcement dates in Indonesian stock market. Earnings announcements produce reactions, both before and after the announcements. Informed investors may use private information before earnings announcements (Christophe, Ferri and Angel, 2004; Porter, 1992). Using technical analysis signals, this study expects that retail investors (uninformed investors) can detect preannouncements react...

An analysis of factors that influence the technical efficiency of Malaysian thermal power plants

International Nuclear Information System (INIS)

See, Kok Fong; Coelli, Tim

2012-01-01

The main objectives of this paper are to measure the technical efficiency levels of Malaysian thermal power plants and to investigate the degree to which various factors influence efficiency levels in these plants. Stochastic frontier analysis (SFA) methods are applied to plant-level data over an eight year period from 1998 to 2005. This is the first comprehensive analysis (to our knowledge) of technical efficiency in the Malaysian electricity generation industry using parametric method. Our empirical results indicate that ownership, plant size and fuel type have a significant influence on technical efficiency levels. We find that publicly-owned power plants obtain average technical efficiencies of 0.68, which is lower than privately-owned power plants, which achieve average technical efficiencies of 0.88. We also observe that larger power plants with more capacity and gas-fired power plants tend to be more technically efficient than other power plants. Finally, we find that plant age and peaking plant type have no statistically significant influence on the technical efficiencies of Malaysian thermal power plants. - Highlights: ► We examine the technical efficiency (TE) levels of Malaysian thermal power plants. ► We also investigate the degree to which various factors influence efficiency levels in these plants. ► Stochastic frontier analysis methods are used. ► Average plant would have to increase their TE level by 21% to reach the efficient frontier. ► Ownership, plant size and fuel type have a significant influence on the TE levels.

Technical specifications of variable speed motors for negative pressure control in hot cell area

Energy Technology Data Exchange (ETDEWEB)

Kim, Seon Duk; Bang, H. S.; Cho, W. K

2002-01-01

Hot cells are the facilities for handling the high radioactive materials and various R and D activities are performed using hot cells. Therefore the control of air flow in hot cell area is very important technology and it is started with the variable speed motor(VSM) controlling the air handling system in that area. This report describes various technical aspects of VS motors and will be useful for understanding the practical technologies of VS motors and also for optimization of the negative pressure controls in hot cell area.

Technical Training on High-Order Spectral Analysis and Thermal Anemometry Applications

Science.gov (United States)

Maslov, A. A.; Shiplyuk, A. N.; Sidirenko, A. A.; Bountin, D. A.

2003-01-01

The topics of thermal anemometry and high-order spectral analyses were the subject of the technical training. Specifically, the objective of the technical training was to study: (i) the recently introduced constant voltage anemometer (CVA) for high-speed boundary layer; and (ii) newly developed high-order spectral analysis techniques (HOSA). Both CVA and HOSA are relevant tools for studies of boundary layer transition and stability.

Technical evaluation of Solar Cells, Inc., CdTe module and array at NREL

Energy Technology Data Exchange (ETDEWEB)

Kroposki, B.; Strand, T.; Hansen, R. [National Renewable Energy Lab., Golden, CO (United States); Powell, R.; Sasala, R. [Solar Cells, Inc., Toledo, OH (United States)

1996-05-01

The Engineering and Technology Validation Team at the National Renewable Energy Laboratory (NREL) conducts in-situ technical evaluations of polycrystalline thin-film photovoltaic (PV) modules and arrays. This paper focuses on the technical evaluation of Solar Cells, Inc., (SCI) cadmium telluride (CdTe) module and array performance by attempting to correlate individual module and array performance. This is done by examining the performance and stability of the modules and array over a period of more than one year. Temperature coefficients for module and array parameters (P{sub max}, V{sub oc}, V{sub max}, I{sub sc}, I{sub max}) are also calculated.

Content Analysis as a Best Practice in Technical Communication Research

Science.gov (United States)

Thayer, Alexander; Evans, Mary; McBride, Alicia; Queen, Matt; Spyridakis, Jan

2007-01-01

Content analysis is a powerful empirical method for analyzing text, a method that technical communicators can use on the job and in their research. Content analysis can expose hidden connections among concepts, reveal relationships among ideas that initially seem unconnected, and inform the decision-making processes associated with many technical…

Technical innovation and management

Energy Technology Data Exchange (ETDEWEB)

Yoon, Yang Cheol

1982-08-15

This book gives explanations of the conception of technical innovation, development plan in Korea, connection between technology and a growth factor in national income, problem of technical innovation in developing country, analysis on cooperation between a developed country and a developing country, evaluation and strategy of technical development in Korea, technical innovation of industry, management of technical industry, analysis of special condition in Korea.

Technical innovation and management

International Nuclear Information System (INIS)

Yoon, Yang Cheol

1982-08-01

This book gives explanations of the conception of technical innovation, development plan in Korea, connection between technology and a growth factor in national income, problem of technical innovation in developing country, analysis on cooperation between a developed country and a developing country, evaluation and strategy of technical development in Korea, technical innovation of industry, management of technical industry, analysis of special condition in Korea.

The potential diagnostic power of circulating tumor cell analysis for non-small-cell lung cancer.

Science.gov (United States)

Ross, Kirsty; Pailler, Emma; Faugeroux, Vincent; Taylor, Melissa; Oulhen, Marianne; Auger, Nathalie; Planchard, David; Soria, Jean-Charles; Lindsay, Colin R; Besse, Benjamin; Vielh, Philippe; Farace, Françoise

2015-01-01

In non-small-cell lung cancer (NSCLC), genotyping tumor biopsies for targetable somatic alterations has become routine practice. However, serial biopsies have limitations: they may be technically difficult or impossible and could incur serious risks to patients. Circulating tumor cells (CTCs) offer an alternative source for tumor analysis that is easily accessible and presents the potential to identify predictive biomarkers to tailor therapies on a personalized basis. Examined here is our current knowledge of CTC detection and characterization in NSCLC and their potential role in EGFR-mutant, ALK-rearranged and ROS1-rearranged patients. This is followed by discussion of the ongoing issues such as the question of CTC partnership as diagnostic tools in NSCLC.

Analysis of farm household technical efficiency in small-scale ...

African Journals Online (AJOL)

Data Envelopment Analysis (DEA) was applied to farm-level cross-sectional data collected in mid-2013 after the implementation of CIP activities. Our empirical results indicate that CIP participants and improved farmers (using using both traditional and modern hives) had the highest average levels of technical efficiencies.

Technical- and environmental-efficiency analysis of irrigated cotton-cropping systems in Punjab, Pakistan using data envelopment analysis.

Science.gov (United States)

Ullah, Asmat; Perret, Sylvain R

2014-08-01

Cotton cropping in Pakistan uses substantial quantities of resources and adversely affects the environment with pollutants from the inputs, particularly pesticides. A question remains regarding to what extent the reduction of such environmental impact is possible without compromising the farmers' income. This paper investigates the environmental, technical, and economic performances of selected irrigated cotton-cropping systems in Punjab to quantify the sustainability of cotton farming and reveal options for improvement. Using mostly primary data, our study quantifies the technical, cost, and environmental efficiencies of different farm sizes. A set of indicators has been computed to reflect these three domains of efficiency using the data envelopment analysis technique. The results indicate that farmers are broadly environmentally inefficient; which primarily results from poor technical inefficiency. Based on an improved input mix, the average potential environmental impact reduction for small, medium, and large farms is 9, 13, and 11 %, respectively, without compromising the economic return. Moreover, the differences in technical, cost, and environmental efficiencies between small and medium and small and large farm sizes were statistically significant. The second-stage regression analysis identifies that the entire farm size significantly affects the efficiencies, whereas exposure to extension and training has positive effects, and the sowing methods significantly affect the technical and environmental efficiencies. Paradoxically, the formal education level is determined to affect the efficiencies negatively. This paper discusses policy interventions that can improve the technical efficiency to ultimately increase the environmental efficiency and reduce the farmers' operating costs.

Solvothermal conversion of technical lignins over NiMo catalysts

DEFF Research Database (Denmark)

Ghafarnejad Parto, Soheila; Christensen, Jakob Munkholt; Pedersen, Lars Saaby

Scope: Lignin, cellulose and hemicellulose are the main constituents of plants cell walls. Lignin is an aromatic rich compound, composed of phenolic building blocks. Depending on the method used for isolation of lignin from cellulose and hemicellulose, several types of technical lignin are availa......Scope: Lignin, cellulose and hemicellulose are the main constituents of plants cell walls. Lignin is an aromatic rich compound, composed of phenolic building blocks. Depending on the method used for isolation of lignin from cellulose and hemicellulose, several types of technical lignin...... of the range of available technical lignins. In this work, catalytic conversion of different types of lignin using an alumina supported NiMo catalyst (provided by Haldor Topsøe A/S) is conducted in ethanol at 310 ˚C with initial hydrogen pressure of 25 barg. The reaction time was set to 3 hours. Proton......, attributed as ‘bio-oil’. GC-MS-FID analysis was used for identification and quantification of the bio-oil and ethanol rich light fraction. The molecular weight of the oil fraction was determined by size exclusion chromatography (SEC). Elemental analysis (Eurovector EuroEA3000) was conducted for measuring...

Label-free quantitative cell division monitoring of endothelial cells by digital holographic microscopy

Science.gov (United States)

Kemper, Björn; Bauwens, Andreas; Vollmer, Angelika; Ketelhut, Steffi; Langehanenberg, Patrik; Müthing, Johannes; Karch, Helge; von Bally, Gert

2010-05-01

Digital holographic microscopy (DHM) enables quantitative multifocus phase contrast imaging for nondestructive technical inspection and live cell analysis. Time-lapse investigations on human brain microvascular endothelial cells demonstrate the use of DHM for label-free dynamic quantitative monitoring of cell division of mother cells into daughter cells. Cytokinetic DHM analysis provides future applications in toxicology and cancer research.

Evaluating Technical Efficiency of Nursing Care Using Data Envelopment Analysis and Multilevel Modeling.

Science.gov (United States)

Min, Ari; Park, Chang Gi; Scott, Linda D

2016-05-23

Data envelopment analysis (DEA) is an advantageous non-parametric technique for evaluating relative efficiency of performance. This article describes use of DEA to estimate technical efficiency of nursing care and demonstrates the benefits of using multilevel modeling to identify characteristics of efficient facilities in the second stage of analysis. Data were drawn from LTCFocUS.org, a secondary database including nursing home data from the Online Survey Certification and Reporting System and Minimum Data Set. In this example, 2,267 non-hospital-based nursing homes were evaluated. Use of DEA with nurse staffing levels as inputs and quality of care as outputs allowed estimation of the relative technical efficiency of nursing care in these facilities. In the second stage, multilevel modeling was applied to identify organizational factors contributing to technical efficiency. Use of multilevel modeling avoided biased estimation of findings for nested data and provided comprehensive information on differences in technical efficiency among counties and states. © The Author(s) 2016.

Predictors of employer satisfaction: technical and non-technical skills.

Science.gov (United States)

Danielson, Jared A; Wu, Tsui-Feng; Fales-Williams, Amanda J; Kirk, Ryan A; Preast, Vanessa A

2012-01-01

Employers of 2007-2009 graduates from Iowa State University College of Veterinary Medicine were asked to respond to a survey regarding their overall satisfaction with their new employees as well as their new employees' preparation in several technical and non-technical skill areas. Seventy-five responses contained complete data and were used in the analysis. Four technical skill areas (data collection, data interpretation, planning, and taking action) and five non-technical skill areas (interpersonal skills, ability to deal with legal issues, business skills, making referrals, and problem solving) were identified. All of the skill area subscales listed above had appropriate reliability (Cronbach's alpha>0.70) and were positively and significantly correlated with overall employer satisfaction. Results of two simultaneous regression analyses indicated that of the four technical skill areas, taking action is the most salient predictor of employer satisfaction. Of the five non-technical skill areas, interpersonal skills, business skills, making referrals, and problem solving were the most important skills in predicting employer satisfaction. Hierarchical regression analysis revealed that all technical skills explained 25% of the variation in employer satisfaction; non-technical skills explained an additional 42% of the variation in employer satisfaction.

Technical efficiency analysis for oilseed sunflower farms: a case study in Erzurum, Turkey.

Science.gov (United States)

Külekçi, Murat

2010-07-01

The main purpose of this study was to examine the technical efficiency of farms producing sunflower in Erzurum, Turkey and to identify factors that might be causing inefficiency. Stochastic frontier analysis was used to measure technical efficiency. One hundred and seventeen randomly selected farms were interviewed for farm-level data in the 2004-2005 production period. Results revealed that the mean technical efficiency for the sunflower farms, estimated by the stochastic production frontier, is 64%. At full technical efficiency, on average, the farmers could reduce their inputs by around 56% without reducing their sunflower production, simply by improving technical efficiency. In the inefficiency model the parameter estimates showed that older farmers, higher level of farmer's education, more experienced farmers, larger farm size and higher information score resulted in lower technical inefficiency, while bigger family size and more credit usage resulted in higher technical inefficiency. This study proposes strategies such as providing better extension services and farmer-training programmes, including more educated people in sunflower farming and also expanding the sunflower-growing area through provision of adequate facilities in order to increase technical efficiency.

Are chartists artists? The determinants and profitability of recommendations based on technical analysis

NARCIS (Netherlands)

Gerritsen, Dirk F.

2016-01-01

The value of technical analysis (TA) has been debated for decades; however, limited evidence exists on the profitability of investment recommendations issued by technical analysts. These ‘chartists’ sometimes claim that TA is an art rather than a science. We evaluated > 5000 TA-based buy and sell

Risk-based analysis methods applied to nuclear power plant technical specifications

International Nuclear Information System (INIS)

Wagner, D.P.; Minton, L.A.; Gaertner, J.P.

1989-01-01

A computer-aided methodology and practical applications of risk-based evaluation of technical specifications are described. The methodology, developed for use by the utility industry, is a part of the overall process of improving nuclear power plant technical specifications. The SOCRATES computer program uses the results of a probabilistic risk assessment or a system-level risk analysis to calculate changes in risk due to changes in the surveillance test interval and/or the allowed outage time stated in the technical specification. The computer program can accommodate various testing strategies (such as staggered or simultaneous testing) to allow modeling of component testing as it is carried out at the plant. The methods and computer program are an integral part of a larger decision process aimed at determining benefits from technical specification changes. These benefits can include cost savings to the utilities by reducing forced shutdowns and decreasing labor requirements for test and maintenance activities, with no adverse impacts on risk. The methodology and the SOCRATES computer program have been used extensively toe valuate several actual technical specifications in case studies demonstrating the methods. Summaries of these applications demonstrate the types of results achieved and the usefulness of the risk-based evaluation in improving the technical specifications

Technical document characterization by data analysis

International Nuclear Information System (INIS)

Mauget, A.

1993-05-01

Nuclear power plants possess documents analyzing all the plant systems, which represents a vast quantity of paper. Analysis of textual data can enable a document to be classified by grouping the texts containing the same words. These methods are used on system manuals for feasibility studies. The system manual is then analyzed by LEXTER and the terms it has selected are examined. We first classify according to style (sentences containing general words, technical sentences, etc.), and then according to terms. However, it will not be possible to continue in this fashion for the 100 system manuals existing, because of lack of sufficient storage capacity. Another solution is being developed. (author)

The Vehicle Integrated Performance Analysis Experience: Reconnecting With Technical Integration

Science.gov (United States)

McGhee, D. S.

2006-01-01

Very early in the Space Launch Initiative program, a small team of engineers at MSFC proposed a process for performing system-level assessments of a launch vehicle. Aimed primarily at providing insight and making NASA a smart buyer, the Vehicle Integrated Performance Analysis (VIPA) team was created. The difference between the VIPA effort and previous integration attempts is that VIPA a process using experienced people from various disciplines, which focuses them on a technically integrated assessment. The foundations of VIPA s process are described. The VIPA team also recognized the need to target early detailed analysis toward identifying significant systems issues. This process is driven by the T-model for technical integration. VIPA s approach to performing system-level technical integration is discussed in detail. The VIPA process significantly enhances the development and monitoring of realizable project requirements. VIPA s assessment validates the concept s stated performance, identifies significant issues either with the concept or the requirements, and then reintegrates these issues to determine impacts. This process is discussed along with a description of how it may be integrated into a program s insight and review process. The VIPA process has gained favor with both engineering and project organizations for being responsive and insightful

Analysis of Technical Specifications of the Egyptian and French Electronic Storybooks (e-Storybook)

Science.gov (United States)

Atta, Mohammed Mahmoud; Abd El Wahab, Shaimaa Mahmoud

2015-01-01

This research aims at analysing technical specifications in a sample of Egyptian and French electronic storybooks (e-storybooks), to identify similarities and differences in technical specifications of children's e-storybooks and create a verified analysis list to be used for evaluation of e-storybooks. For this purpose, 32 e-storybooks in CD…

Technical Efficiency of Thai Manufacturing SMEs: A Stochastic Frontier Analysis

Directory of Open Access Journals (Sweden)

Teerawat Charoenrat

2013-03-01

Full Text Available AbstractA major motivation of this study is to examine the factors that are the most important in contributing to the relatively poor efficiency performance of Thai manufacturing small and medium sized enterprises (SMEs. The results obtained will be significant in devising effective policies aimed at tackling this poor performance.This paper uses data on manufacturing SMEs in the North-eastern region of Thailand in 2007 as a case study, by applying a stochastic frontier analysis (SFA and a technical inefficiency effects model. The empirical results obtained indicate that the mean technical efficiency of all categories of manufacturing SMEs in theNorth-eastern region is 43%, implying that manufacturing SMEs have high levels of technical inefficiency in their production processes.Manufacturing SMEs in the North-eastern region are particularly labour-intensive. The empirical results of the technical inefficiency effects model suggest that skilled labour, the municipal area and ownership characteristics are important firm-specific factors affecting technical efficiency. The paper argues that the government should play a more substantial role in developing manufacturing SMEs in the North-eastern provinces through: providing training programs for employees and employers; encouraging a greater usage of capital and technology in the production process of SMEs; enhancing the efficiency of state-ownedenterprises; encouraging a wide range of ownership forms; and improving information and communications infrastructure.

Comparative technical-economic analysis of the low temperature heating systems

International Nuclear Information System (INIS)

Sharevski, Vasko; Sharevski, Milan

1994-01-01

A method for comparative technical-economic analysis between low temperature heating systems and heating systems with fossil fuel boiler plant, heat pump heating system and electrical heating systems is presented. The single and combined heating systems are analyzed. The technical-economic priority application of the heating system is determined according to the prices of the low temperature heat energy, fossil fuel heat energy, electrical energy, as well as to the coefficient of the annual use of the installed heating capacity, investment expenses, structure of the combined heating system and coefficient of performances of the heat pump. The combined heating system, composed with a low temperature heating subsystem, which is used to cover the base heat demands, and a oil boiler plant heating subsystem, for the top heat demands, have technical-economic justification and wide range of priority application, in comparison with single heating systems. (author)

Accuracy Combination Test of Classical and Modern Technical Analysis: A Case Study in Stock of PT Wijaya Karya Tbk

OpenAIRE

Agustini Hamid

2016-01-01

The research aimed to measure the accuracy and combination of Classic and Modern Technical Analysis. PT Wijaya Karya Tbk (WIKA)’s stock in two periods is the sample of research. Technical analysis was used to predict stock prices by observing changes in historical share price. Practically, technical analysis is divided into Classic Technical and Modern. Research was conducted by library study and using a computer software. Microsft Excel was used for the simulation and Chart Nexus for analyzi...

Technical analysis of photovoltaic/wind systems with hydrogen storage

Directory of Open Access Journals (Sweden)

Bakić Vukman V.

2012-01-01

Full Text Available The technical analysis of a hybrid wind-photovoltaic energy system with hydrogen gas storage was studied. The market for the distributed power generation based on renewable energy is increasing, particularly for the standalone mini-grid applications. The main design components of PV/Wind hybrid system are the PV panels, the wind turbine and an alkaline electrolyzer with tank. The technical analysis is based on the transient system simulation program TRNSYS 16. The study is realized using the meteorological data for a Typical Metrological Year (TMY for region of Novi Sad, Belgrade cities and Kopaonik national park in Serbia. The purpose of the study is to design a realistic energy system that maximizes the use of renewable energy and minimizes the use of fossil fuels. The reduction in the CO2 emissions is also analyzed in the paper. [Acknowledgment. This paper is the result of the investigations carried out within the scientific project TR33036 supported by the Ministry of Science of the Republic of Serbia.

RepExplore: addressing technical replicate variance in proteomics and metabolomics data analysis.

Science.gov (United States)

Glaab, Enrico; Schneider, Reinhard

2015-07-01

High-throughput omics datasets often contain technical replicates included to account for technical sources of noise in the measurement process. Although summarizing these replicate measurements by using robust averages may help to reduce the influence of noise on downstream data analysis, the information on the variance across the replicate measurements is lost in the averaging process and therefore typically disregarded in subsequent statistical analyses.We introduce RepExplore, a web-service dedicated to exploit the information captured in the technical replicate variance to provide more reliable and informative differential expression and abundance statistics for omics datasets. The software builds on previously published statistical methods, which have been applied successfully to biomedical omics data but are difficult to use without prior experience in programming or scripting. RepExplore facilitates the analysis by providing a fully automated data processing and interactive ranking tables, whisker plot, heat map and principal component analysis visualizations to interpret omics data and derived statistics. Freely available at http://www.repexplore.tk enrico.glaab@uni.lu Supplementary data are available at Bioinformatics online. © The Author 2015. Published by Oxford University Press.

An Integrated Workflow To Assess Technical and Biological Variability of Cell Population Frequencies in Human Peripheral Blood by Flow Cytometry.

Science.gov (United States)

Burel, Julie G; Qian, Yu; Lindestam Arlehamn, Cecilia; Weiskopf, Daniela; Zapardiel-Gonzalo, Jose; Taplitz, Randy; Gilman, Robert H; Saito, Mayuko; de Silva, Aruna D; Vijayanand, Pandurangan; Scheuermann, Richard H; Sette, Alessandro; Peters, Bjoern

2017-02-15

In the context of large-scale human system immunology studies, controlling for technical and biological variability is crucial to ensure that experimental data support research conclusions. In this study, we report on a universal workflow to evaluate both technical and biological variation in multiparameter flow cytometry, applied to the development of a 10-color panel to identify all major cell populations and T cell subsets in cryopreserved PBMC. Replicate runs from a control donation and comparison of different gating strategies assessed the technical variability associated with each cell population and permitted the calculation of a quality control score. Applying our panel to a large collection of PBMC samples, we found that most cell populations showed low intraindividual variability over time. In contrast, certain subpopulations such as CD56 T cells and Temra CD4 T cells were associated with high interindividual variability. Age but not gender had a significant effect on the frequency of several populations, with a drastic decrease in naive T cells observed in older donors. Ethnicity also influenced a significant proportion of immune cell population frequencies, emphasizing the need to account for these covariates in immune profiling studies. We also exemplify the usefulness of our workflow by identifying a novel cell-subset signature of latent tuberculosis infection. Thus, our study provides a universal workflow to establish and evaluate any flow cytometry panel in systems immunology studies. Copyright © 2017 by The American Association of Immunologists, Inc.

Grain intermodal terminals: evaluation of pure technical efficiency by Data Envelopment Analysis

Directory of Open Access Journals (Sweden)

Maria Gabriela Mendonça Peixoto

Full Text Available Abstract This paper aimed to verify if terminals with productive efficiency also have pure technical efficiency, using DEA (Data Envelopment Analysis technique. The research approach was the qualitative-quantitative or mixed, with exploratory purpose; the research method defined was the case study (multicases; data were collected through interviews using a structured questionnaire and non-probability for convenience sampling. While the application of Charnes, Cooper and Rhodes (CCR model observed that only three (4, 7 and 11, of the twelve analyzed Decision Making Units (DMUs have total technical efficiency, through Banker, Charnes and Cooper (BCC model, it was possible to observe that these terminals were the only ones with pure technical efficiency. The three inefficient DMUs (1, 2 and 12 showed pure technical efficiency, suggesting that these terminals might present probable scale operations’ inefficiency, aspect not addressed in this paper.

Technical noise supplement : TeNS : a technical supplement to the Traffic Noise Analysis Protocol.

Science.gov (United States)

1998-10-01

The purpose of this Technical Noise Supplement (TeNS) is to provide technical background : information on transportation-related noise in general and highway traffic noise in : particular. It is designed to elaborate on technical concepts and procedu...

Transcriptome Analysis of Mycobacteria-Specific CD4+ T Cells Identified by Activation-Induced Expression of CD154.

Science.gov (United States)

Kunnath-Velayudhan, Shajo; Goldberg, Michael F; Saini, Neeraj K; Johndrow, Christopher T; Ng, Tony W; Johnson, Alison J; Xu, Jiayong; Chan, John; Jacobs, William R; Porcelli, Steven A

2017-10-01

Analysis of Ag-specific CD4 + T cells in mycobacterial infections at the transcriptome level is informative but technically challenging. Although several methods exist for identifying Ag-specific T cells, including intracellular cytokine staining, cell surface cytokine-capture assays, and staining with peptide:MHC class II multimers, all of these have significant technical constraints that limit their usefulness. Measurement of activation-induced expression of CD154 has been reported to detect live Ag-specific CD4 + T cells, but this approach remains underexplored and, to our knowledge, has not previously been applied in mycobacteria-infected animals. In this article, we show that CD154 expression identifies adoptively transferred or endogenous Ag-specific CD4 + T cells induced by Mycobacterium bovis bacillus Calmette-Guérin vaccination. We confirmed that Ag-specific cytokine production was positively correlated with CD154 expression by CD4 + T cells from bacillus Calmette-Guérin-vaccinated mice and show that high-quality microarrays can be performed from RNA isolated from CD154 + cells purified by cell sorting. Analysis of microarray data demonstrated that the transcriptome of CD4 + CD154 + cells was distinct from that of CD154 - cells and showed major enrichment of transcripts encoding multiple cytokines and pathways of cellular activation. One notable finding was the identification of a previously unrecognized subset of mycobacteria-specific CD4 + T cells that is characterized by the production of IL-3. Our results support the use of CD154 expression as a practical and reliable method to isolate live Ag-specific CD4 + T cells for transcriptomic analysis and potentially for a range of other studies in infected or previously immunized hosts. Copyright © 2017 by The American Association of Immunologists, Inc.

The Technical Report: An Analysis of Information Design and Packaging for an Inelastic Market.

Science.gov (United States)

Pinelli, Thomas E.; And Others

As part of an evaluation of its scientific and technical information program, the National Aeronautics and Space Administration (NASA) conducted a review and analysis of structural, language, and presentation components of its technical report form. The investigation involved comparing and contrasting NASA's publications standards for technical…

Technical and Feasibility Analysis of Gasoline and Natural Gas Fuelled Vehicles

Directory of Open Access Journals (Sweden)

Charalambos Chasos

2014-03-01

Full Text Available There is recent interest for the utilisation of natural gas for empowering the internal combustion engines (ICE of vehicles. The production of novel natural gas ICE for vehicles, as well as the conversion of existing gasoline fuelled ICE of vehicles to natural gas fuelled ICE are new technologies which require to be analysed and assessed. The objective of the present study is to examine the adaptation of natural gas as vehicle fuel and carry out a technical analysis and an economical feasibility analysis of the two types of ICE vehicles, namely gasoline and natural gas fuelled vehicles. The technical model uses the physical properties of the two fuels and the performance factors of internal combustion engines including brake thermal efficiency. The resulting exhaust gas emissions are also estimated by the technical model using combustion calculations which provide the expected levels of exhaust gas emissions. Based on the analysis with the technical model, comparisons of the two types of engines are performed. Furthermore, the estimated performance characteristics of the two types of engines, along with local statistical data on annual fuel imports and annual fuel consumption for transportation and data on the vehicles fleet for the case study of Cyprus are used as input in the economical model. For the base year 2013, data of natural gas price is also used in the economical model. The economical model estimates the capital cost, the carbon dioxide emissions avoidance of fines, the net present value and the internal rate of return of the investment of large scale adaptation of natural gas fuelled vehicles for the case study. From the results and comparisons, conclusions are drawn and recommendations are provided for the adaptation of natural gas vehicles which can provide improved performance with reduced pollutant emissions.

Thermodynamic analysis of biofuels as fuels for high temperature fuel cells

Science.gov (United States)

Milewski, Jarosław; Bujalski, Wojciech; Lewandowski, Janusz

2013-02-01

Based on mathematical modeling and numerical simulations, applicativity of various biofuels on high temperature fuel cell performance are presented. Governing equations of high temperature fuel cell modeling are given. Adequate simulators of both solid oxide fuel cell (SOFC) and molten carbonate fuel cell (MCFC) have been done and described. Performance of these fuel cells with different biofuels is shown. Some characteristics are given and described. Advantages and disadvantages of various biofuels from the system performance point of view are pointed out. An analysis of various biofuels as potential fuels for SOFC and MCFC is presented. The results are compared with both methane and hydrogen as the reference fuels. The biofuels are characterized by both lower efficiency and lower fuel utilization factors compared with methane. The presented results are based on a 0D mathematical model in the design point calculation. The governing equations of the model are also presented. Technical and financial analysis of high temperature fuel cells (SOFC and MCFC) are shown. High temperature fuel cells can be fed by biofuels like: biogas, bioethanol, and biomethanol. Operational costs and possible incomes of those installation types were estimated and analyzed. A comparison against classic power generation units is shown. A basic indicator net present value (NPV) for projects was estimated and commented.

Thermodynamic analysis of biofuels as fuels for high temperature fuel cells

Directory of Open Access Journals (Sweden)

Milewski Jarosław

2013-02-01

Full Text Available Based on mathematical modeling and numerical simulations, applicativity of various biofuels on high temperature fuel cell performance are presented. Governing equations of high temperature fuel cell modeling are given. Adequate simulators of both solid oxide fuel cell (SOFC and molten carbonate fuel cell (MCFC have been done and described. Performance of these fuel cells with different biofuels is shown. Some characteristics are given and described. Advantages and disadvantages of various biofuels from the system performance point of view are pointed out. An analysis of various biofuels as potential fuels for SOFC and MCFC is presented. The results are compared with both methane and hydrogen as the reference fuels. The biofuels are characterized by both lower efficiency and lower fuel utilization factors compared with methane. The presented results are based on a 0D mathematical model in the design point calculation. The governing equations of the model are also presented. Technical and financial analysis of high temperature fuel cells (SOFC and MCFC are shown. High temperature fuel cells can be fed by biofuels like: biogas, bioethanol, and biomethanol. Operational costs and possible incomes of those installation types were estimated and analyzed. A comparison against classic power generation units is shown. A basic indicator net present value (NPV for projects was estimated and commented.

The Reliability of Technical and Tactical Tagging Analysis Conducted by a Semi-Automatic VTS in Soccer.

Science.gov (United States)

Beato, Marco; Jamil, Mikael; Devereux, Gavin

2018-06-01

The Video Tracking multiple cameras system (VTS) is a technology that records two-dimensional position data (x and y) at high sampling rates (over 25 Hz). The VTS is of great interest because it can record external load variables as well as collect technical and tactical parameters. Performance analysis is mainly focused on physical demands, yet less attention has been afforded to technical and tactical factors. Digital.Stadium® VTS is a performance analysis device widely used at national and international levels (i.e. Italian Serie A, Euro 2016) and the reliability evaluation of its technical tagging analysis (e.g. shots, passes, assists, set pieces) could be paramount for its application at elite level competitions, as well as in research studies. Two professional soccer teams, with 30 male players (age 23 ± 5 years, body mass 78.3 ± 6.9 kg, body height 1.81 ± 0.06 m), were monitored in the 2016 season during a friendly match and data analysis was performed immediately after the game ended. This process was then replicated a week later (4 operators conducted the data analysis in each week). This study reports a near perfect relationship between Match and its Replication. R2 coefficients (relationships between Match and Replication) were highly significant for each of the technical variables considered (p technical tagging data accurately.

Surface Fire Hazards Analysis Technical Report-Constructor Facilities

International Nuclear Information System (INIS)

Flye, R.E.

2000-01-01

The purpose of this Fire Hazards Analysis Technical Report (hereinafter referred to as Technical Report) is to assess the risk from fire within individual fire areas to ascertain whether the U.S. Department of Energy (DOE) fire safety objectives are met. The objectives identified in DOE Order 420.1, Change 2, Facility Safety, Section 4.2, establish requirements for a comprehensive fire and related hazards protection program for facilities sufficient to minimize the potential for: The occurrence of a fire or related event; A fire that causes an unacceptable on-site or off-site release of hazardous or radiological material that will threaten the health and safety of employees, the public, or the environment; Vital DOE programs suffering unacceptable interruptions as a result of fire and related hazards; Property losses from a fire and related events exceeding defined limits established by DOE; and Critical process controls and safety class systems being damaged as a result of a fire and related events

Technical Work Plan For: Meteorological Monitoring and Data Analysis

International Nuclear Information System (INIS)

C.T. Bastian

2003-01-01

The meteorological monitoring and analysis program has three overall objectives. First, the program will acquire qualified meteorological data from monitoring activities in the Environmental Safety and Health (ES and H) network, including appropriate controls on measuring and test equipment. All work will be completed in accordance with U.S. Department of Energy (DOE) Office of Repository Development (ORD) administrative procedures and Bechtel SAIC Co., LLC (BSC) line procedures. The continuously operating monitoring program includes measuring and test equipment calibrations, operational checks, preventive and corrective maintenance, and data collection. Second, the program will process the raw monitoring data collected in the field and submit technically reviewed, traceable data to the Technical Data Management System (TDMS) and the Records Processing Center. Third, reports containing analyses or calculations could be created to provide information to data requesters

Resolving tumor heterogeneity: genes involved in chordoma cell development identified by low-template analysis of morphologically distinct cells.

Directory of Open Access Journals (Sweden)

Amin El-Heliebi

Full Text Available The classical sacrococcygeal chordoma tumor presents with a typical morphology of lobulated myxoid tumor tissue with cords, strands and nests of tumor cells. The population of cells consists of small non-vacuolated cells, intermediate cells with a wide range of vacuolization and large heavily vacuolated (physaliferous cells. To date analysis was only performed on bulk tumor mass because of its rare incidence, lack of suited model systems and technical limitations thereby neglecting its heterogeneous composition. We intended to clarify whether the observed cell types are derived from genetically distinct clones or represent different phenotypes. Furthermore, we aimed at elucidating the differences between small non-vacuolated and large physaliferous cells on the genomic and transcriptomic level. Phenotype-specific analyses of small non-vacuolated and large physaliferous cells in two independent chordoma cell lines yielded four candidate genes involved in chordoma cell development. UCHL3, coding for an ubiquitin hydrolase, was found to be over-expressed in the large physaliferous cell phenotype of MUG-Chor1 (18.7-fold and U-CH1 (3.7-fold cells. The mannosyltransferase ALG11 (695-fold and the phosphatase subunit PPP2CB (18.6-fold were found to be up-regulated in large physaliferous MUG-Chor1 cells showing a similar trend in U-CH1 cells. TMEM144, an orphan 10-transmembrane family receptor, yielded contradictory data as cDNA microarray analysis showed up- but RT-qPCR data down-regulation in large physaliferous MUG-Chor1 cells. Isolation of few but morphologically identical cells allowed us to overcome the limitations of bulk analysis in chordoma research. We identified the different chordoma cell phenotypes to be part of a developmental process and discovered new genes linked to chordoma cell development representing potential targets for further research in chordoma tumor biology.

Assessing the Possibility of Implementing Tools of Technical Analysys for Real Estate Market Analysis

Directory of Open Access Journals (Sweden)

Brzezicka Justyna

2016-06-01

Full Text Available Technical analysis (TA and its different aspects are widely used to study the capital market. In the traditional approach, this analysis is used to determine the probability of changes in current rates on the basis of their past changes, accounting for factors which had, have or may have an influence on shaping the supply and demand of a given asset. In the practical sense, TA is a set of techniques used for assessing the value of an asset based on the analysis of the asset's trajectories as well as statistical tools.

Citation analysis of Computer Standards & Interfaces: Technical or also non-technical focus?

NARCIS (Netherlands)

G. van de Kaa (Geerten); H.J. de Vries (Henk); B. Baskaran (Balakumaran)

2015-01-01

textabstractThis paper analyzes to which extent research published in Computer Standards & Interfaces (CSI) has a technical focus. We find that CSI has been following its scope very closely in the last three years and that the majority of its publications have a technical focus. Articles published

Technical-tactical analysis of capoeira game: contributions to think the teach-learning-training metodology

Directory of Open Access Journals (Sweden)

Vinícius Thiago De Melo

2015-05-01

Full Text Available This article presented a critical analysis on the internal structure of capoeira game. This research took place from empirical observation and literature review. The analysis focused on the technical and tactical aspects of the game, relating concepts and principles of sports pedagogy to capoeira specifically. It was noted that the game of capoeira can be classified as sociomotor/collective, however, this has presented variations, and can also be classified as psychomotor/individual. Through the analysis of the capoeira game performed in that article was verified that hardly a single teaching method would address all the technical and tactical elements involved in this activity. Therefore, was detach the importance of using multiples methods of teaching-learning-training, which might facilitate the rescue of the capoeira game from their historical-cultural foundations, which is characterized by "mandinga", "malice", in other words, a technical-tactical game which involves unpredictability, strategies, improvisation, creativity and decision-making.

On the Use of Student Data in Efficiency Analysis--Technical Efficiency in Swedish Upper Secondary School

Science.gov (United States)

Waldo, Staffan

2007-01-01

While individual data form the base for much empirical analysis in education, this is not the case for analysis of technical efficiency. In this paper, efficiency is estimated using individual data which is then aggregated to larger groups of students. Using an individual approach to technical efficiency makes it possible to carry out studies on a…

Analysis and Design of Fuel Cell Systems for Aviation

Directory of Open Access Journals (Sweden)

Thomas Kadyk

2018-02-01

Full Text Available In this paper, the design of fuel cells for the main energy supply of passenger transportation aircraft is discussed. Using a physical model of a fuel cell, general design considerations are derived. Considering different possible design objectives, the trade-off between power density and efficiency is discussed. A universal cost–benefit curve is derived to aid the design process. A weight factor w P is introduced, which allows incorporating technical (e.g., system mass and efficiency as well as non-technical design objectives (e.g., operating cost, emission goals, social acceptance or technology affinity, political factors. The optimal fuel cell design is not determined by the characteristics of the fuel cell alone, but also by the characteristics of the other system components. The fuel cell needs to be designed in the context of the whole energy system. This is demonstrated by combining the fuel cell model with simple and detailed design models of a liquid hydrogen tank. The presented methodology and models allows assessing the potential of fuel cell systems for mass reduction of future passenger aircraft.

Accident Damage Analysis Module (ADAM) – Technical Guidance, Software tool for Consequence Analysis calculations

OpenAIRE

FABBRI LUCIANO; BINDA MASSIMO; BRUINEN DE BRUIN YURI

2017-01-01

This report provides a technical description of the modelling and assumptions of the Accident Damage Analysis Module (ADAM) software application, which has been recently developed by the Joint Research Centre (JRC) of the European Commission (EC) to assess physical effects of an industrial accident resulting from an unintended release of a dangerous substance

Technical-tactical analysis of youth olympic taekwondo combat.

Science.gov (United States)

Tornello, Francesco; Capranica, Laura; Minganti, Carlo; Chiodo, Salvatore; Condello, Giancarlo; Tessitore, Antonio

2014-04-01

The purpose of this study was to define the technical and tactical profiles of official youth taekwondo competitions played under the most recent rules of the International Taekwondo Federation. Tactical actions (i.e., attack, defense, and block), technical executions (from 1- to 4-point scores), kicking legs (i.e., front/rear and right/left), and overall technical effectiveness were investigated in relation to match outcome of semifinal and final competitions (n = 50) of youth (aged 13-14 years) black belt athletes during the Italian Taekwondo Cadet Championship. Differences (p technical exchanges showed differences (p technical executions. Winners resulted more efficient (p technical and tactical variables. In general, these findings showed that Cadets tend to adopt an offensive strategy. In considering that the adoption of the new electronic system requires athletes to execute correct technical actions to have a score assigned, coaches should emphasize the effectiveness of scoring techniques and help athletes to effectively improve their defense and counterattack capabilities.

Evaluation of preparation methods for MS-based analysis of intestinal epithelial cell proteomes

DEFF Research Database (Denmark)

Hesselager, Marianne Overgaard; Codrea, Marius Cosmin; Bendixen, Emøke

2015-01-01

analyzed by LC and electrospray QTOF-MS. The methods were evaluated according to efficiency, purity, transmembrane protein recovery, as well as for suitability to large-scale preparations. Our data clearly demonstrate that mucosal shaving is by far the best-suited method for in-depth MS analysis in terms...... are low in abundance, and large amounts of sample is needed for their preparation and for undertaking MS-based analysis. The aim of this study was to evaluate three different methods for isolation and preparation of pig intestinal epithelial cells for MS-based analysis of the proteome. Samples were...... of ease and speed of sample preparation, as well as protein recovery. In comparison, more gentle methods where intestinal epithelial cells are harvested by shaking are more time consuming, result in lower protein yield, and are prone to increased technical variation due to multiple steps involved....

The Profitability of the Strategy Linking Fundamental, Portfolio and Technical Analysis on the Polish Capital Market

Directory of Open Access Journals (Sweden)

Flotyński Marcin

2016-12-01

Full Text Available In the article, several methods of taking investment decisions are described: a fundamental, portfolio, and technical analysis. They constitute different approaches which are convenient for different types of investors with various expectations and time horizons of their investments. The simultaneous combination of these three analyses is not popular. The aim of this study is to test the effectiveness of simultaneous use of a fundamental analysis, portfolio analysis, and technical analysis for shares quoted on the Warsaw Stock Exchange (WSE in 2000–2007. The research hypothesis is advanced that the concurrent-linked application of a fundamental, portfolio, and technical analysis brings better results than the separate use of these analyses. Models of capital market, such as CAPM and APT, have been used, as well as P/E ratio, Return on Equity (RoE, Relative Strength Index (RSI, and Exponential Moving Average (EMA. The combination of a financial analysis, technical indicators, and models of the capital market in order to invest on the stock exchange is author’s own method. In general, the survey has been carried out on the grounds of quantitative methods (financial analysis, regression model, and multi regression model and a comparative analysis. The results of the research have been used to create diversified portfolios on the WSE. It occurs that the concurrent use of the three analyses brings the highest rate of return of a portfolio.

Analysis of occupational accidents: prevention through the use of additional technical safety measures for machinery.

Science.gov (United States)

Dźwiarek, Marek; Latała, Agata

2016-01-01

This article presents an analysis of results of 1035 serious and 341 minor accidents recorded by Poland's National Labour Inspectorate (PIP) in 2005-2011, in view of their prevention by means of additional safety measures applied by machinery users. Since the analysis aimed at formulating principles for the application of technical safety measures, the analysed accidents should bear additional attributes: the type of machine operation, technical safety measures and the type of events causing injuries. The analysis proved that the executed tasks and injury-causing events were closely connected and there was a relation between casualty events and technical safety measures. In the case of tasks consisting of manual feeding and collecting materials, the injuries usually occur because of the rotating motion of tools or crushing due to a closing motion. Numerous accidents also happened in the course of supporting actions, like removing pollutants, correcting material position, cleaning, etc.

Technical feasibility of the implementing of the paper analysis in forensic documentoscopy

International Nuclear Information System (INIS)

Perez Alfaro, Cesar Alonso

2013-01-01

Technical feasibility has determined the implementation of the paper analysis in forensic documentoscopy. Methods of non-destructive and destructive testing are focused in the study. The dimensions, thickness, opacity, brightness and air permeability are analyzed by the methods of non-destructive testing. The analysis of pH, fiber, humidity and ashes are performed by destructive methods. 10 samples of paper type 'Bond' are examined of the main importers from country. The chemical and anatomy of the wood are explained. The results of the non-destructive methods have achieved to differentiate 8 of the 10 samples studied. The two remaining samples have achieved to differentiate by the fibers analysis and ashes analysis. The pH has determined in the 10 samples that the pulping method has been basic. The technical differentiation of the 'Bond' paper has been possible for use in forensic documentoscopy. The fibers present in the paper are observed applying the dye 'Graff C' and using the microscope. The dye method 'Graff C' has allowed a morphologic differentiation of the organic composition of the sample of paper [es

Technical Note: Introduction of variance component analysis to setup error analysis in radiotherapy

Energy Technology Data Exchange (ETDEWEB)

Matsuo, Yukinori, E-mail: ymatsuo@kuhp.kyoto-u.ac.jp; Nakamura, Mitsuhiro; Mizowaki, Takashi; Hiraoka, Masahiro [Department of Radiation Oncology and Image-applied Therapy, Kyoto University, 54 Shogoin-Kawaharacho, Sakyo, Kyoto 606-8507 (Japan)

2016-09-15

Purpose: The purpose of this technical note is to introduce variance component analysis to the estimation of systematic and random components in setup error of radiotherapy. Methods: Balanced data according to the one-factor random effect model were assumed. Results: Analysis-of-variance (ANOVA)-based computation was applied to estimate the values and their confidence intervals (CIs) for systematic and random errors and the population mean of setup errors. The conventional method overestimates systematic error, especially in hypofractionated settings. The CI for systematic error becomes much wider than that for random error. The ANOVA-based estimation can be extended to a multifactor model considering multiple causes of setup errors (e.g., interpatient, interfraction, and intrafraction). Conclusions: Variance component analysis may lead to novel applications to setup error analysis in radiotherapy.

Technical Note: Introduction of variance component analysis to setup error analysis in radiotherapy

International Nuclear Information System (INIS)

Matsuo, Yukinori; Nakamura, Mitsuhiro; Mizowaki, Takashi; Hiraoka, Masahiro

2016-01-01

Purpose: The purpose of this technical note is to introduce variance component analysis to the estimation of systematic and random components in setup error of radiotherapy. Methods: Balanced data according to the one-factor random effect model were assumed. Results: Analysis-of-variance (ANOVA)-based computation was applied to estimate the values and their confidence intervals (CIs) for systematic and random errors and the population mean of setup errors. The conventional method overestimates systematic error, especially in hypofractionated settings. The CI for systematic error becomes much wider than that for random error. The ANOVA-based estimation can be extended to a multifactor model considering multiple causes of setup errors (e.g., interpatient, interfraction, and intrafraction). Conclusions: Variance component analysis may lead to novel applications to setup error analysis in radiotherapy.

Technical/economical analysis of bioenergy systems

International Nuclear Information System (INIS)

Solantausta, Y.

1998-01-01

The objectives of the IEA Bioenergy Technoeconomic Analysis Activity are: (1) To promote development of thermochemical biomass conversion methods by carrying out selected site specific feasibility studies in participating countries. Both agricultural and woody biomasses will be converted either into electricity or boiler fuels; (2) To compare advanced technologies to commercial alternatives based on technoeconomic basis to establish future development needs, and (3) To facilitate information exchange between participants on relevant basic process issues. Five countries (Finland, Canada, USA, Norway, Austria) are participating to the Activity. Initially two feasibility studies are planned for each country. Each study has three common elements: site specific, technical, and economic data. The site specific cases are described below in short. Products in the cases are electricity, heat and fuel oil. Total of two cases per country are planned. (orig.)

Energy. Application of solar energy in dwellings: A technical and economical analysis for the European community

Science.gov (United States)

1980-03-01

The technical possibilities and economical limitations of solar heating systems for the application in swimming pools, hot water preparation, space heating and air conditioning were investigated. This analysis was performed for dwellings with special consideration of the climatic differences in each community. The computer program, which was used for solar system calculations, and all mathematical models, for technical and economical analysis were elucidated. In the technical and economical analysis, the most suitable solar system sizes for each community was determined. Four types of solar collectors were investigated. The single glass selective collector proved to be the most cost effective collector in all the above applications, provided the the additional cost for the selective coating is not more than 20DM/cu. From the results of the analysis certain recommendations were derived, which can improve the rapid implementation of solar heating systems into the market.

MARKOWITZ' MODEL WITH FUNDAMENTAL AND TECHNICAL ANALYSIS – COMPLEMENTARY METHODS OR NOT

Directory of Open Access Journals (Sweden)

Branka Marasović

2011-02-01

Full Text Available As it is well known there are few “starting points” in portfolio optimization process, i.e. in the stock selection process. Famous Markowitz’ optimization model is unavoidable in this job. On the other side, someone may say that the indicators of the fundamental analysis must be the starting point. Beside that, the suggestions of the technical analysis must be taken into consideration. There are really numerous studies of the each approach separately, but it is almost impossible to find researches combining these approaches in logic and efficient unity. The main task of the paper is to find out if these approaches are complementary and if they are, how to apply them as efficient unit process. The empirical part of the study uses share sample from the Croatian stock market. Beside Markowitz’ MV model, fundamental and technical analysis, big role in the paper has an original multi-criterion approach.

How a submarine returns to periscope depth: analysing complex socio-technical systems using Cognitive Work Analysis.

Science.gov (United States)

Stanton, Neville A; Bessell, Kevin

2014-01-01

This paper presents the application of Cognitive Work Analysis to the description of the functions, situations, activities, decisions, strategies, and competencies of a Trafalgar class submarine when performing the function of returning to periscope depth. All five phases of Cognitive Work Analysis are presented, namely: Work Domain Analysis, Control Task Analysis, Strategies Analysis, Social Organisation and Cooperation Analysis, and Worker Competencies Analysis. Complex socio-technical systems are difficult to analyse but Cognitive Work Analysis offers an integrated way of analysing complex systems with the core of functional means-ends analysis underlying all of the other representations. The joined-up analysis offers a coherent framework for understanding how socio-technical systems work. Data were collected through observation and interviews at different sites across the UK. The resultant representations present a statement of how the work domain and current activities are configured in this complex socio-technical system. This is intended to provide a baseline, from which all future conceptions of the domain may be compared. The strength of the analysis is in the multiple representations from which the constraints acting on the work may be analysed. Future research needs to challenge the assumptions behind these constraints in order to develop new ways of working. Copyright © 2013 Elsevier Ltd and The Ergonomics Society. All rights reserved.

Imagining Technicities

DEFF Research Database (Denmark)

Liboriussen, Bjarke; Plesner, Ursula

2011-01-01

to the elements of taste and skill. In the final analysis those references were synthesized as five imagined technicities: the architect, the engineer, the client, the Chinese, and the Virtual World native. Because technicities are often assumed and rarely discussed as actants who influence practice, their role......, this article focuses on innovative uses of virtual worlds in architecture. We interviewed architects, industrial designers and other practitioners. Conceptually supported by an understanding of technicity found in Cultural Studies, the interviews were then coded with a focus on interviewees’ references...... in cooperation and development of ICTs seems to pass unnoticed. However, since they are aligned into ICTs, technicities impact innovation....

Socio-technical Betwixtness

DEFF Research Database (Denmark)

Bossen, Claus

2017-01-01

the intrinsically social and technical interwovenness of design, and the necessity of including affected people and stakeholders in the design process. This betwixtness of socio-technical design is demonstrated by the analysis of two IT systems for healthcare: a foundational model for electronic healthcare records......This chapter focusses on two challenges for socio-technical design: Having to choose between different rationales for design, and the adequate understanding and depiction of the work to be redesigned. These two challenges betwixt the otherwise strong tenets of socio-technical design of pointing out......, and an IT system organizing hospital porters’ work. The conceptual background for the analysis of the cases is provided by a short introduction to different rationales for organizational design, and by pointing to the differences between a linear, rationalistic versus an interactional depiction of work....

Analysis of Physiological, Technical, and Tactical Analysis during a Friendly Football Match of Elite U19.

Science.gov (United States)

Ortega, Juan Ignacio; Evangelio, Carlos; Clemente, Filipe Manuel; Martins, Fernando Manuel Lourenço; González-Víllora, Sixto

2016-06-16

The main objective was to analyze a friendly match of youth elite soccer players identifying the variance of tactical and physiological response parameters during the game. In addition, detecting the impact of both halves on player performance. For the purposes of this study twenty-two U19 players were analyzed playing 11v11. Activity profile, heart rate (HR and HRmax), grouped in five different zones were analyzed via Bluetooth technology, technical performance was analyzed by the Team Sport Assessment Procedure (TSAP), and tactical performance was measured by Social Network Analysis. A comparison of heart rate responses showed significant main effects in the halves (p = 0.001; η p 2 = 0.623). A comparison between tactical position and technical performance had significant main effects (p = 0.001; η p 2 = 0.390). Tactical position showed statistically significant effects on tactical prominence (p = 0.002; η p 2 = 0.296). Therefore, fatigue is a component distinguished in technical/tactical parameters, such as volume of play and efficiency index. Results suggest that fatigue effects may constrain technical performance and, for that reason, the use of instruments to monitor the fatigue effect during matches may be suggested.

Analysis of Physiological, Technical, and Tactical Analysis during a Friendly Football Match of Elite U19

Directory of Open Access Journals (Sweden)

Juan Ignacio Ortega

2016-06-01

Full Text Available The main objective was to analyze a friendly match of youth elite soccer players identifying the variance of tactical and physiological response parameters during the game. In addition, detecting the impact of both halves on player performance. For the purposes of this study twenty-two U19 players were analyzed playing 11v11. Activity profile, heart rate (HR and HRmax, grouped in five different zones were analyzed via Bluetooth technology, technical performance was analyzed by the Team Sport Assessment Procedure (TSAP, and tactical performance was measured by Social Network Analysis. A comparison of heart rate responses showed significant main effects in the halves (p = 0.001; η p 2 = 0.623. A comparison between tactical position and technical performance had significant main effects (p = 0.001; η p 2 = 0.390. Tactical position showed statistically significant effects on tactical prominence (p = 0.002; η p 2 = 0.296. Therefore, fatigue is a component distinguished in technical/tactical parameters, such as volume of play and efficiency index. Results suggest that fatigue effects may constrain technical performance and, for that reason, the use of instruments to monitor the fatigue effect during matches may be suggested.

Establishment and Analysis of Cancer Stem-Like and Non-Cancer Stem-Like Clone Cells from the Human Colon Cancer Cell Line SW480.

Directory of Open Access Journals (Sweden)

Akari Takaya

Full Text Available Human cancer stem-like cells (CSCs/cancer-initiating cells (CICs can be isolated as side population (SP cells, aldehyde dehydrogenase high (ALDHhigh cells or cell surface marker-positive cells including CD44+ cells and CD133+ cells. CSCs/CICs and non-CSCs/CICs are unstable in in vitro culture, and CSCs/CICs can differentiate into non-CSCs/CICs and some non-CSCs/CICs can dedifferentiate into CSCs/CICs. Therefore, experiments using a large amount of CSCs/CICs are technically very difficult. In this study, we isolated single cell clones from SP cells and main population (MP cells derived from the human colon cancer cell line SW480. SP analysis revealed that SP clone cells had relatively high percentages of SP cells, whereas MP clone cells showed very few SP cells, and the phenotypes were sustainable for more than 2 months of in vitro culture. Xenograft transplantation revealed that SP clone cells have higher tumor-initiating ability than that of MP clone cells and SP clone cell showed higher chemo-resistance compared with MP clone cells. These results indicate that SP clone cells derived from SW480 cells are enriched with CSCs/CICs, whereas MP clone cells are pure non-CSCs/CICs. SP clone cells and MP clone cells are a very stable in vitro CSC/CIC-enriched and non-CSC/CIC model for further analysis.

Establishment and Analysis of Cancer Stem-Like and Non-Cancer Stem-Like Clone Cells from the Human Colon Cancer Cell Line SW480.

Science.gov (United States)

Takaya, Akari; Hirohashi, Yoshihiko; Murai, Aiko; Morita, Rena; Saijo, Hiroshi; Yamamoto, Eri; Kubo, Terufumi; Nakatsugawa, Munehide; Kanaseki, Takayuki; Tsukahara, Tomohide; Tamura, Yasuaki; Takemasa, Ichiro; Kondo, Toru; Sato, Noriyuki; Torigoe, Toshihiko

2016-01-01

Human cancer stem-like cells (CSCs)/cancer-initiating cells (CICs) can be isolated as side population (SP) cells, aldehyde dehydrogenase high (ALDHhigh) cells or cell surface marker-positive cells including CD44+ cells and CD133+ cells. CSCs/CICs and non-CSCs/CICs are unstable in in vitro culture, and CSCs/CICs can differentiate into non-CSCs/CICs and some non-CSCs/CICs can dedifferentiate into CSCs/CICs. Therefore, experiments using a large amount of CSCs/CICs are technically very difficult. In this study, we isolated single cell clones from SP cells and main population (MP) cells derived from the human colon cancer cell line SW480. SP analysis revealed that SP clone cells had relatively high percentages of SP cells, whereas MP clone cells showed very few SP cells, and the phenotypes were sustainable for more than 2 months of in vitro culture. Xenograft transplantation revealed that SP clone cells have higher tumor-initiating ability than that of MP clone cells and SP clone cell showed higher chemo-resistance compared with MP clone cells. These results indicate that SP clone cells derived from SW480 cells are enriched with CSCs/CICs, whereas MP clone cells are pure non-CSCs/CICs. SP clone cells and MP clone cells are a very stable in vitro CSC/CIC-enriched and non-CSC/CIC model for further analysis.

#Indigenous: A Technical and Decolonial Analysis of Activist Uses of Hashtags Across Social Movements

Directory of Open Access Journals (Sweden)

Marisa Elena Duarte

2017-12-01

Full Text Available A mixed methods network analysis of the content, circulation, and amount of data Native American activists circulated through Twitter during the 2016 US presidential election reveals contours of the technical challenges and social and political boundaries shaping Native American political life. A comparison of the results with a mainstream American dataset reveals how tweets propagated by Native American rights activists are characteristically more likely to focus on life-and-death issues. Analysis of the findings from an Indigenous perspective opens possibilities for considering activist, scientific, experiential, technical, governmental, political, and metaphysical aspects of Indigenous Internet research.

Analysis of occupational accidents: prevention through the use of additional technical safety measures for machinery

Science.gov (United States)

Dźwiarek, Marek; Latała, Agata

2016-01-01

This article presents an analysis of results of 1035 serious and 341 minor accidents recorded by Poland's National Labour Inspectorate (PIP) in 2005–2011, in view of their prevention by means of additional safety measures applied by machinery users. Since the analysis aimed at formulating principles for the application of technical safety measures, the analysed accidents should bear additional attributes: the type of machine operation, technical safety measures and the type of events causing injuries. The analysis proved that the executed tasks and injury-causing events were closely connected and there was a relation between casualty events and technical safety measures. In the case of tasks consisting of manual feeding and collecting materials, the injuries usually occur because of the rotating motion of tools or crushing due to a closing motion. Numerous accidents also happened in the course of supporting actions, like removing pollutants, correcting material position, cleaning, etc. PMID:26652689

Airborne incidents : an econometric analysis of severity, December 31, 2014 : technical summary

Science.gov (United States)

2014-12-31

This is a technical summary of the Airborne Incidents: An Econometric Analysis of Severity main report. : Airborne loss of separation incidents occur when an aircraft breaches the defined separation limit (vertical and/or horizontal) with anoth...

The logic of Technical Standardisation

DEFF Research Database (Denmark)

Nedergaard, Peter

In this paper technical standardisation is understood and explained in a model where economic analysis is coupled with an analysis of the political system as proposed in rational choice theory. The aim is to answer both the question why various countries (e.g. the United States versus European...... countries) let either the market or public intervention determine the mode of technical standardisation and the possible implications of these two ways of organizing technical standardisation from an economic and a political point of view. Based upon the analysis of the paper a couple of general policy...... recommendations are made concerning the mode of technical standardisation....

DNDO Analysis Cell Concept

Energy Technology Data Exchange (ETDEWEB)

Pagh, Richard T.; Dimmerling, Paul J.; Guillen, Zoe C.; Hoyt, Joel R.; Jarman, Kenneth D.; Kernan, Warnick J.; Reichmuth, Barbara A.; Rohlfing, Kerrie S.; Schweppe, John E.; Sego, Landon H.; Shergur, Jason M.; Siciliano, Edward R.; Woodring, Mitchell L.

2014-03-12

The Domestic Nuclear Detection Office (DNDO) has a mission of implementing rad/nuc interdiction capabilities for a managed and coordinated response to threats, integration of federal nuclear forensics programs, and coordinating the development of the global nuclear detection and reporting architecture. In the process of executing this mission, DNDO has generated substantial information, data, technical results, operational workflows and analytical tools. The effective utilization of these resources is an overarching goal of the organization. After nearly a decade of performing work, DNDO faces a challenge in capitalizing on the large amount of data, reports, processes, tools, and people. As new work is being planned, managers and researchers need to have an understating of what information has been collected, what tools are available, the collaborations which can be utilized to propel the work forward, processes to plan and execute, and how to present conclusions and results that can assist the government in making decisions. This type of challenge can be met through the use of a series of organized and connected elements which form a broader structure (cell) that promotes cross utilization of elements such that they can be tailored (analyzed) to fit the context of the problem to be solved. The development of an analysis cell for DNDO will address the challenges of utilizing existing elements, identifying gaps, annually reporting the performance of rad/nuc interdiction instrumentation, and planning the execution of future work.

Pareto analysis of critical factors affecting technical institution evaluation

Directory of Open Access Journals (Sweden)

Victor Gambhir

2012-08-01

Full Text Available With the change of education policy in 1991, more and more technical institutions are being set up in India. Some of these institutions provide quality education, but others are merely concentrating on quantity. These stakeholders are in a state of confusion about decision to select the best institute for their higher educational studies. Although various agencies including print media provide ranking of these institutions every year, but their results are controversial and biased. In this paper, the authors have made an endeavor to find the critical factors for technical institution evaluation from literature survey. A Pareto analysis has also been performed to find the intensity of these critical factors in evaluation. This will not only help the stake holders in taking right decisions but will also help the management of institutions in benchmarking for identifying the most important critical areas to improve the existing system. This will in turn help Indian economy.

Functionalized single-walled carbon nanotube-based fuel cell benchmarked against US DOE 2017 technical targets.

Science.gov (United States)

Jha, Neetu; Ramesh, Palanisamy; Bekyarova, Elena; Tian, Xiaojuan; Wang, Feihu; Itkis, Mikhail E; Haddon, Robert C

2013-01-01

Chemically modified single-walled carbon nanotubes (SWNTs) with varying degrees of functionalization were utilized for the fabrication of SWNT thin film catalyst support layers (CSLs) in polymer electrolyte membrane fuel cells (PEMFCs), which were suitable for benchmarking against the US DOE 2017 targets. Use of the optimum level of SWNT -COOH functionality allowed the construction of a prototype SWNT-based PEMFC with total Pt loading of 0.06 mg(Pt)/cm²--well below the value of 0.125 mg(Pt)/cm² set as the US DOE 2017 technical target for total Pt group metals (PGM) loading. This prototype PEMFC also approaches the technical target for the total Pt content per kW of power (<0.125 g(PGM)/kW) at cell potential 0.65 V: a value of 0.15 g(Pt)/kW was achieved at 80°C/22 psig testing conditions, which was further reduced to 0.12 g(Pt)/kW at 35 psig back pressure.

Gene Expression Analysis of Immunostained Endothelial Cells Isolated from Formaldehyde-fixated Paraffin Embedded Tumors Using Laser Capture Microdissection – a Technical Report

Science.gov (United States)

Kaneko, Tomoatsu; Okiji, Takashi; Kaneko, Reika; Suda, Hideaki; Nör, Jacques E.

2009-01-01

Laser capture microdissection (LCM) allows microscopic procurement of specific cell types from tissue sections that can then be used for gene expression analysis. In conventional LCM, frozen tissues stained with hematoxylin are normally used to the molecular analysis. Recent studies suggested that it is possible to carry out gene expression analysis of formaldehyde-fixated paraffin embedded (FFPE) tissues that were stained with hematoxylin. However, it is still unclear if quantitative gene expression analyses can be performed from LCM cells from FFPE tissues that were subjected to immunostaining to enhance identification of target cells. In this proof-of-principle study, we analyzed by RT-PCR and real time PCR the expression of genes in factor VIII immunostained human endothelial cells that were dissected from FFPE tissues by LCM. We observed that immunostaining should be performed at 4°C to preserve the mRNA from the cells. The expression of Bcl-2 in the endothelial cells was evaluated by RT-PCR and by real time PCR. GAPDH and 18S were used as house keeping genes for RT-PCR and real time PCR, respectively. This report unveils a method for quantitative gene expression analysis in cells that were identified by immunostaining and retrieved by LCM from FFPE tissues. This method is ideally suited for the analysis of relatively rare cell types within a tissue, and should improve on our ability to perform differential diagnosis of pathologies as compared to conventional LCM. PMID:19425073

Strategy of technical innovation

International Nuclear Information System (INIS)

Lee, Ga Jong

1990-12-01

This book deals with policy of scientific technique and technical innovation such as research for development and types of technical innovation, historical development and process of technical innovation, economic growth, technology change and investment for research and development, structure and form of technical transfer with the meaning process, from, structure and theory, economic growth and investment of research and development with experiential analysis and case study on strategy of technical innovation in electron and fine chemical industry.

Comparison of reverse transcription-quantitative polymerase chain reaction methods and platforms for single cell gene expression analysis.

Science.gov (United States)

Fox, Bridget C; Devonshire, Alison S; Baradez, Marc-Olivier; Marshall, Damian; Foy, Carole A

2012-08-15

Single cell gene expression analysis can provide insights into development and disease progression by profiling individual cellular responses as opposed to reporting the global average of a population. Reverse transcription-quantitative polymerase chain reaction (RT-qPCR) is the "gold standard" for the quantification of gene expression levels; however, the technical performance of kits and platforms aimed at single cell analysis has not been fully defined in terms of sensitivity and assay comparability. We compared three kits using purification columns (PicoPure) or direct lysis (CellsDirect and Cells-to-CT) combined with a one- or two-step RT-qPCR approach using dilutions of cells and RNA standards to the single cell level. Single cell-level messenger RNA (mRNA) analysis was possible using all three methods, although the precision, linearity, and effect of lysis buffer and cell background differed depending on the approach used. The impact of using a microfluidic qPCR platform versus a standard instrument was investigated for potential variability introduced by preamplification of template or scaling down of the qPCR to nanoliter volumes using laser-dissected single cell samples. The two approaches were found to be comparable. These studies show that accurate gene expression analysis is achievable at the single cell level and highlight the importance of well-validated experimental procedures for low-level mRNA analysis. Copyright © 2012 Elsevier Inc. All rights reserved.

Benefit Analysis Report, United States Air Force Technical Order Management Systems (AFTOMS)

Science.gov (United States)

1989-08-01

This report prepared by the Transportation Systems Center (TSC) concludes an analysis of the Technical Order (TO) costs and benefits, which was originally undertaken as part of the US Air Force Computer-aided Acquisition and Logistics Support (CALS) ...

Application of objective clinical human reliability analysis (OCHRA) in assessment of technical performance in laparoscopic rectal cancer surgery.

Science.gov (United States)

Foster, J D; Miskovic, D; Allison, A S; Conti, J A; Ockrim, J; Cooper, E J; Hanna, G B; Francis, N K

2016-06-01

Laparoscopic rectal resection is technically challenging, with outcomes dependent upon technical performance. No robust objective assessment tool exists for laparoscopic rectal resection surgery. This study aimed to investigate the application of the objective clinical human reliability analysis (OCHRA) technique for assessing technical performance of laparoscopic rectal surgery and explore the validity and reliability of this technique. Laparoscopic rectal cancer resection operations were described in the format of a hierarchical task analysis. Potential technical errors were defined. The OCHRA technique was used to identify technical errors enacted in videos of twenty consecutive laparoscopic rectal cancer resection operations from a single site. The procedural task, spatial location, and circumstances of all identified errors were logged. Clinical validity was assessed through correlation with clinical outcomes; reliability was assessed by test-retest. A total of 335 execution errors identified, with a median 15 per operation. More errors were observed during pelvic tasks compared with abdominal tasks (p technical performance of laparoscopic rectal surgery.

Comparative Analysis of Dynamic Cell Viability, Migration and Invasion Assessments by Novel Real-Time Technology and Classic Endpoint Assays

Science.gov (United States)

Limame, Ridha; Wouters, An; Pauwels, Bea; Fransen, Erik; Peeters, Marc; Lardon, Filip; De Wever, Olivier; Pauwels, Patrick

2012-01-01

Background Cell viability and motility comprise ubiquitous mechanisms involved in a variety of (patho)biological processes including cancer. We report a technical comparative analysis of the novel impedance-based xCELLigence Real-Time Cell Analysis detection platform, with conventional label-based endpoint methods, hereby indicating performance characteristics and correlating dynamic observations of cell proliferation, cytotoxicity, migration and invasion on cancer cells in highly standardized experimental conditions. Methodology/Principal Findings Dynamic high-resolution assessments of proliferation, cytotoxicity and migration were performed using xCELLigence technology on the MDA-MB-231 (breast cancer) and A549 (lung cancer) cell lines. Proliferation kinetics were compared with the Sulforhodamine B (SRB) assay in a series of four cell concentrations, yielding fair to good correlations (Spearman's Rho 0.688 to 0.964). Cytotoxic action by paclitaxel (0–100 nM) correlated well with SRB (Rho>0.95) with similar IC50 values. Reference cell migration experiments were performed using Transwell plates and correlated by pixel area calculation of crystal violet-stained membranes (Rho 0.90) and optical density (OD) measurement of extracted dye (Rho>0.95). Invasion was observed on MDA-MB-231 cells alone using Matrigel-coated Transwells as standard reference method and correlated by OD reading for two Matrigel densities (Rho>0.95). Variance component analysis revealed increased variances associated with impedance-based detection of migration and invasion, potentially caused by the sensitive nature of this method. Conclusions/Significance The xCELLigence RTCA technology provides an accurate platform for non-invasive detection of cell viability and motility. The strong correlations with conventional methods imply a similar observation of cell behavior and interchangeability with other systems, illustrated by the highly correlating kinetic invasion profiles on different

Comparative analysis of dynamic cell viability, migration and invasion assessments by novel real-time technology and classic endpoint assays.

Directory of Open Access Journals (Sweden)

Ridha Limame

Full Text Available BACKGROUND: Cell viability and motility comprise ubiquitous mechanisms involved in a variety of (pathobiological processes including cancer. We report a technical comparative analysis of the novel impedance-based xCELLigence Real-Time Cell Analysis detection platform, with conventional label-based endpoint methods, hereby indicating performance characteristics and correlating dynamic observations of cell proliferation, cytotoxicity, migration and invasion on cancer cells in highly standardized experimental conditions. METHODOLOGY/PRINCIPAL FINDINGS: Dynamic high-resolution assessments of proliferation, cytotoxicity and migration were performed using xCELLigence technology on the MDA-MB-231 (breast cancer and A549 (lung cancer cell lines. Proliferation kinetics were compared with the Sulforhodamine B (SRB assay in a series of four cell concentrations, yielding fair to good correlations (Spearman's Rho 0.688 to 0.964. Cytotoxic action by paclitaxel (0-100 nM correlated well with SRB (Rho>0.95 with similar IC(50 values. Reference cell migration experiments were performed using Transwell plates and correlated by pixel area calculation of crystal violet-stained membranes (Rho 0.90 and optical density (OD measurement of extracted dye (Rho>0.95. Invasion was observed on MDA-MB-231 cells alone using Matrigel-coated Transwells as standard reference method and correlated by OD reading for two Matrigel densities (Rho>0.95. Variance component analysis revealed increased variances associated with impedance-based detection of migration and invasion, potentially caused by the sensitive nature of this method. CONCLUSIONS/SIGNIFICANCE: The xCELLigence RTCA technology provides an accurate platform for non-invasive detection of cell viability and motility. The strong correlations with conventional methods imply a similar observation of cell behavior and interchangeability with other systems, illustrated by the highly correlating kinetic invasion profiles on

A meta-analysis of motivational interviewing process: Technical, relational, and conditional process models of change.

Science.gov (United States)

Magill, Molly; Apodaca, Timothy R; Borsari, Brian; Gaume, Jacques; Hoadley, Ariel; Gordon, Rebecca E F; Tonigan, J Scott; Moyers, Theresa

2018-02-01

In the present meta-analysis, we test the technical and relational hypotheses of Motivational Interviewing (MI) efficacy. We also propose an a priori conditional process model where heterogeneity of technical path effect sizes should be explained by interpersonal/relational (i.e., empathy, MI Spirit) and intrapersonal (i.e., client treatment seeking status) moderators. A systematic review identified k = 58 reports, describing 36 primary studies and 40 effect sizes (N = 3,025 participants). Statistical methods calculated the inverse variance-weighted pooled correlation coefficient for the therapist to client and the client to outcome paths across multiple target behaviors (i.e., alcohol use, other drug use, other behavior change). Therapist MI-consistent skills were correlated with more client change talk (r = .55, p technical hypothesis was supported. Specifically, proportion MI consistency was related to higher proportion change talk (r = .11, p = .004) and higher proportion change talk was related to reductions in risk behavior at follow up (r = -.16, p technical hypothesis path effect sizes was partially explained by inter- and intrapersonal moderators. This meta-analysis provides additional support for the technical hypothesis of MI efficacy; future research on the relational hypothesis should occur in the field rather than in the context of clinical trials. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

Technical Analysis of Hydrogen Production

Energy Technology Data Exchange (ETDEWEB)

Ali T-Raissi

2005-01-14

The aim of this work was to assess issues of cost, and performance associated with the production and storage of hydrogen via following three feedstocks: sub-quality natural gas (SQNG), ammonia (NH{sub 3}), and water. Three technology areas were considered: (1) Hydrogen production utilizing SQNG resources, (2) Hydrogen storage in ammonia and amine-borane complexes for fuel cell applications, and (3) Hydrogen from solar thermochemical cycles for splitting water. This report summarizes our findings with the following objectives: Technoeconomic analysis of the feasibility of the technology areas 1-3; Evaluation of the hydrogen production cost by technology areas 1; and Feasibility of ammonia and/or amine-borane complexes (technology areas 2) as a means of hydrogen storage on-board fuel cell powered vehicles. For each technology area, we reviewed the open literature with respect to the following criteria: process efficiency, cost, safety, and ease of implementation and impact of the latest materials innovations, if any. We employed various process analysis platforms including FactSage chemical equilibrium software and Aspen Technologies AspenPlus and HYSYS chemical process simulation programs for determining the performance of the prospective hydrogen production processes.

Longitudinal Trend Analysis of Performance Indicators for South Carolina's Technical Colleges

Science.gov (United States)

Hossain, Mohammad Nurul

2010-01-01

This study included an analysis of the trend of performance indicators for the technical college sector of higher education in South Carolina. In response to demands for accountability and transparency in higher education, the state of South Carolina developed sector specific performance indicators to measure various educational outcomes for each…

Biosensors for Cell Analysis.

Science.gov (United States)

Zhou, Qing; Son, Kyungjin; Liu, Ying; Revzin, Alexander

2015-01-01

Biosensors first appeared several decades ago to address the need for monitoring physiological parameters such as oxygen or glucose in biological fluids such as blood. More recently, a new wave of biosensors has emerged in order to provide more nuanced and granular information about the composition and function of living cells. Such biosensors exist at the confluence of technology and medicine and often strive to connect cell phenotype or function to physiological or pathophysiological processes. Our review aims to describe some of the key technological aspects of biosensors being developed for cell analysis. The technological aspects covered in our review include biorecognition elements used for biosensor construction, methods for integrating cells with biosensors, approaches to single-cell analysis, and the use of nanostructured biosensors for cell analysis. Our hope is that the spectrum of possibilities for cell analysis described in this review may pique the interest of biomedical scientists and engineers and may spur new collaborations in the area of using biosensors for cell analysis.

Technical conservatism in the design and analysis of a nuclear-waste repository in basalt

International Nuclear Information System (INIS)

Jones, K.A.

1982-01-01

The US Department of Energy's National Waste Terminal Storage Program has adopted a policy of technical conservatism to guide the design and analysis of geologic disposal systems for commercial high-level radioactive waste. Technical conservatism serves as the programmatic philosophy for managing uncertainty in the performance of the disposal system. The implementation of technical conservatism as applied to a nuclear waste repository in basalt is discussed. Preliminary assessments of the performance of the waste package, repository, and site subsystems are compared to key proposed regulatory criteria. The comparison shows that there are substantial safety margins in the predicted performance of the nuclear waste repository in basalt

A Socio-Technical Analysis of Patient Accessible Electronic Health Records.

Science.gov (United States)

Hägglund, Maria; Scandurra, Isabella

2017-01-01

In Sweden, and internationally, there is a movement towards increased transparency in healthcare including giving patients online access to their electronic health records (EHR). The purpose of this paper is to analyze the Swedish patient accessible EHR (PAEHR) service using a socio-technical framework, to increase the understanding of factors that influence the design, implementation, adoption and use of the service. Using the Sitting and Singh socio-technical framework as a basis for analyzing the Swedish PAEHR system and its context indicated that there are many stakeholders engaged in these types of services, with different driving forces and incentives that may influence the adoption and usefulness of PAEHR services. The analysis was useful in highlighting important areas that need to be further explored in evaluations of PAEHR services, and can act as a guide when planning evaluations of any PAEHR service.

Aircraft/Air Traffic Management Functional Analysis Model: Technical Description. 2.0

Science.gov (United States)

Etheridge, Melvin; Plugge, Joana; Retina, Nusrat

1998-01-01

The Aircraft/Air Traffic Management Functional Analysis Model, Version 2.0 (FAM 2.0), is a discrete event simulation model designed to support analysis of alternative concepts in air traffic management and control. FAM 2.0 was developed by the Logistics Management Institute (LMI) under a National Aeronautics and Space Administration (NASA) contract. This document provides a technical description of FAM 2.0 and its computer files to enable the modeler and programmer to make enhancements or modifications to the model. Those interested in a guide for using the model in analysis should consult the companion document, Aircraft/Air Traffic Management Functional Analysis Model, Version 2.0 Users Manual.

Technical factors that affect anastomotic integrity following esophagectomy: systematic review and meta-analysis.

Science.gov (United States)

Markar, Sheraz R; Arya, Shobhit; Karthikesalingam, Alan; Hanna, George B

2013-12-01

Due to the significant contribution of anastomotic leak, with its disastrous consequences to patient morbidity and mortality, multiple parameters have been proposed and individually meta-analyzed for the formation of the ideal esophagogastric anastomosis following cancer resection. The purpose of this pooled analysis was to examine the main technical parameters that impact on anastomotic integrity. Medline, Embase, trial registries, and conference proceedings were searched. Technical factors evaluated included hand-sewn versus stapled esophagogastric anastomosis (EGA), cervical versus thoracic EGA, minimally invasive versus open esophagectomy, anterior versus posterior route of reconstruction and ischemic conditioning of the gastric conduit. The outcome of interest was the incidence of anastomotic leak, for which pooled odds ratios were calculated for each technical factor. No significant difference in the incidence of anastomotic leak was demonstrated for the following technical factors: hand-sewn versus stapled EGA, minimally invasive versus open esophagectomy, anterior versus posterior route of reconstruction and ischemic conditioning of the gastric conduit. Four randomized, controlled trials comprising 298 patients were included that compared cervical and thoracic EGA. Anastomotic leak was seen more commonly in the cervical group (13.64 %) than in the thoracic group (2.96 %). Pooled analysis demonstrated a significantly increased incidence of anastomotic leak in the cervical group (pooled odds ratio = 4.73; 95 % CI 1.61-13.9; P = 0.005). A tailored surgical approach to the patient's physiology and esophageal cancer stage is the most important factor that influences anastomotic integrity after esophagectomy.

NAEP 1999 Long-Term Trend Technical Analysis Report: Three Decades of Student Performance. NCES 2005-484

Science.gov (United States)

Allen, Nancy L.; McClellan, Catherine A.; Stoeckel, Joan J.

2005-01-01

This report provides an update to the technical analysis procedures documenting the 1996 National Assessment of Educational Progress (NAEP) as presented in "The NAEP 1996 Technical Report" (Allen, Carlson, and Zelenak, 1999). It describes how the 1999 long-term trend data were incorporated into the trend analyses. Since no national main…

Technical efficiency of women's health prevention programs in Bucaramanga, Colombia: a four-stage analysis.

Science.gov (United States)

Ruiz-Rodriguez, Myriam; Rodriguez-Villamizar, Laura A; Heredia-Pi, Ileana

2016-10-13

Primary Health Care (PHC) is an efficient strategy to improve health outcomes in populations. Nevertheless, studies of technical efficiency in health care have focused on hospitals, with very little on primary health care centers. The objective of the present study was to use the Data Envelopment Analysis to estimate the technical efficiency of three women's health promotion and disease prevention programs offered by primary care centers in Bucaramanga, Colombia. Efficiency was measured using a four-stage data envelopment analysis with a series of Tobit regressions to account for the effect of quality outcomes and context variables. Input/output information was collected from the institutions' records, chart reviews and personal interviews. Information about contextual variables was obtained from databases from the primary health program in the municipality. A jackknife analysis was used to assess the robustness of the results. The analysis was based on data from 21 public primary health care centers. The average efficiency scores, after adjusting for quality and context, were 92.4 %, 97.5 % and 86.2 % for the antenatal care (ANC), early detection of cervical cancer (EDCC) and family planning (FP) programs, respectively. On each program, 12 of the 21 (57.1 %) health centers were found to be technically efficient; having had the best-practice frontiers. Adjusting for context variables changed the scores and reference rankings of the three programs offered by the health centers. The performance of the women's health prevention programs offered by the centers was found to be heterogeneous. Adjusting for context and health care quality variables had a significant effect on the technical efficiency scores and ranking. The results can serve as a guide to strengthen management and organizational and planning processes related to local primary care services operating within a market-based model such as the one in Colombia.

Descriptive analysis of context evaluation instrument for technical oral presentation skills evaluation: A case study in English technical communication course

Science.gov (United States)

Mohamed, Abdullah-Adnan; Asmawi, Adelina; Hamid, Mohd Rashid Ab; Mustafa, Zainol bin

2015-02-01

This paper reports a pilot study of Context Evaluation using a self-developed questionnaire distributed among engineering undergraduates at a university under study. The study aims to validate the self-developed questionnaires used in the Context evaluation, a component in the CIPP Model. The Context evaluation assesses background information for needs, assets, problems and opportunities relevant to beneficiaries of the study in a defined environment. Through the questionnaire, background information for the assessment of needs, assets and problems related to the engineering undergraduates' perceptions on the teaching and learning of technical oral presentation skills was collected and analysed. The questionnaire was developed using 5-points Likert scale to measure the constructs under study. They were distributed to 100 respondents with 79 returned. The respondents consisted of engineering undergraduates studied at various faculties at one technical university in Malaysia. The descriptive analysis of data for each item which makes up the construct for Context evaluation is found to be high. This implied that engineering undergraduates showed high interest in teaching and learning of technical oral presentation skills, thus their needs are met. Also, they agreed that assets and facilities are conducive to their learning. In conclusion, the context evaluation involving needs and assets factors are both considerably important; their needs are met and the assets and facilities do support their technical oral presentation skills learning experience.

Technical Training: Technical Training Seminar

CERN Multimedia

2004-01-01

Tuesday 30 March TECHNICAL TRAINING SEMINAR From 9:00 to 12:00 and from 13:00 to 16:00 hrs - Council Chamber, Salle B, Salle des Pas Perdus National Instruments (NI) on Tour 2004 Claudia Jüngel, Evrem Yarkin, Joel Clerc, Hervé Baour / NATIONAL INSTRUMENTS The special event NI on Tour 2004, run in Germany, Austria and Switzerland, will be at CERN on March 30. Technical seminars and free introductory courses will be offered all day long in the Council Chamber, Salle B, and Salle des Pas Perdus (buildings 61 and 503). Technical conferences: 09:00 - 12:00 Data acquisition systems on PCs. Industrial measurement and control techniques. 13:00 - 16:00 Advanced LabVIEW software and PXI instrumentation. Measuring instruments and system components for teststand automation. Introductory courses: 09:00 - 12:00 DIAdem: Data analysis and presentation 13:00 - 16:00 Data acquisition with LabVIEW Language: English and French Free special seminar. Registration is recommended with National Instruments Switzerland (please sp...

Technical Training: Technical Training Seminar

CERN Multimedia

2004-01-01

Tuesday 30 March TECHNICAL TRAINING SEMINAR From 9:00 to 12:00 and from 13:00 to 16:00 hrs - Council Chamber, Salle B, Salle des Pas Perdus National Instruments (NI) on Tour 2004 Claudia Jüngel, Evrem Yarkin, Joel Clerc, Hervé Baour / NATIONAL INSTRUMENTS The special event NI on Tour 2004, run in Germany, Austria and Switzerland, will be at CERN on March 30. Technical seminars and free introductory courses will be offered all day long in the Council Chamber, Salle B, and Salle des Pas Perdus (buildings 61 and 503). Technical conferences: 09:00 - 12:00 Data acquisition systems on PCs. Industrial measurement and control techniques. 13:00 - 16:00 Advanced LabVIEW software and PXI instrumentation. Measuring instruments and system components for teststand automation. Introductory courses: 09:00 - 12:00 DIAdem: Data analysis and presentation 13:00 - 16:00 Data acquisition with LabVIEW Language: English and French Free special seminar. Registration is recommended with National Instruments Swi...

Single Cell Isolation and Analysis

Directory of Open Access Journals (Sweden)

Ping Hu

2016-10-01

Full Text Available Increasing evidence shows that the heterogeneity of individual cells within a genetically identical population can be critical to their peculiar function and fate. Conventional cell based assays mainly analysis the average responses from a population cells, while the difference within individual cells may often be masked. The cell size, RNA transcripts and protein expression level are quite different within individual cells and these variations are key point to answer the problems in cancer, neurobiology, stem cell biology, immunology and developmental biology. To better understand the cell-to-cell variations, the single cell analysis can provide much more detailed information which may be helpful for therapeutic decisions in an increasingly personalized medicine. In this review, we will focus on the recent development in single cell analysis, including methods used in single cell isolation, analysis and some application examples. The review provides the historical background to single cell analysis, discusses limitations, and current and future possibilities in this exciting field of research.

A step-by-step workflow for low-level analysis of single-cell RNA-seq data with Bioconductor [version 2; referees: 1 approved, 4 approved with reservations

Directory of Open Access Journals (Sweden)

Aaron T.L. Lun

2016-10-01

Full Text Available Single-cell RNA sequencing (scRNA-seq is widely used to profile the transcriptome of individual cells. This provides biological resolution that cannot be matched by bulk RNA sequencing, at the cost of increased technical noise and data complexity. The differences between scRNA-seq and bulk RNA-seq data mean that the analysis of the former cannot be performed by recycling bioinformatics pipelines for the latter. Rather, dedicated single-cell methods are required at various steps to exploit the cellular resolution while accounting for technical noise. This article describes a computational workflow for low-level analyses of scRNA-seq data, based primarily on software packages from the open-source Bioconductor project. It covers basic steps including quality control, data exploration and normalization, as well as more complex procedures such as cell cycle phase assignment, identification of highly variable and correlated genes, clustering into subpopulations and marker gene detection. Analyses were demonstrated on gene-level count data from several publicly available datasets involving haematopoietic stem cells, brain-derived cells, T-helper cells and mouse embryonic stem cells. This will provide a range of usage scenarios from which readers can construct their own analysis pipelines.

Hanford Site Composite Analysis Technical Approach Description: Groundwater Pathway Dose Calculation.

Energy Technology Data Exchange (ETDEWEB)

Morgans, D. L. [CH2M Hill Plateau Remediation Company, Richland, WA (United States); Lindberg, S. L. [Intera Inc., Austin, TX (United States)

2017-09-20

The purpose of this technical approach document (TAD) is to document the assumptions, equations, and methods used to perform the groundwater pathway radiological dose calculations for the revised Hanford Site Composite Analysis (CA). DOE M 435.1-1, states, “The composite analysis results shall be used for planning, radiation protection activities, and future use commitments to minimize the likelihood that current low-level waste disposal activities will result in the need for future corrective or remedial actions to adequately protect the public and the environment.”

Integrated corridor management initiative : demonstration phase evaluation - Dallas technical capability analysis test plan.

Science.gov (United States)

This report presents the test plan for conducting the Technical Capability Analysis for the United States : Department of Transportation (U.S. DOT) evaluation of the Dallas U.S. 75 Integrated Corridor : Management (ICM) Initiative Demonstration. The ...

Dynamic analysis of CO₂ labeling and cell respiration using membrane-inlet mass spectrometry.

Science.gov (United States)

Yang, Tae Hoon

2014-01-01

Here, we introduce a mass spectrometry-based analytical method and relevant technical details for dynamic cell respiration and CO2 labeling analysis. Such measurements can be utilized as additional information and constraints for model-based (13)C metabolic flux analysis. Dissolved dynamics of oxygen consumption and CO2 mass isotopomer evolution from (13)C-labeled tracer substrates through different cellular processes can be precisely measured on-line using a miniaturized reactor system equipped with a membrane-inlet mass spectrometer. The corresponding specific rates of physiologically relevant gases and CO2 mass isotopomers can be quantified within a short-term range based on the liquid-phase dynamics of dissolved fermentation gases.

Technical Performance Analysis of Iran Premier League Soccer Players in 2012-2013 Season

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Javani Mohsen

2015-10-01

Full Text Available Background and purpose of study : analysis of IRAN premier league soccer players’ technical performance in season 2012-2013, using a computerized match analysis system (Borhan Mobin Development Management Co, IRAN. Material and methods: in this study, data were obtained from 120 players, who performed in competitions 90 minutes. The players were classified into 3 positional roles: defenders, midfielders and forwards. Technical performance variables analysis included: total passes, total successful passes, pass accuracy, total shots; total shots to target, shot accuracy, ball interception and ball losses. The data were statistically analyzed by one-way ANOVA, Kruskal-Wallis, Mann-Whitney U and Tukey post hoc test. Results : The findings of this study showed that players performed about 45 passes per competition. Midfielders and defenders had significantly higher number of passes than forwards. Pass accuracy was about 67% and there were no significant differences between positional roles. Also, the players performed about 0.8 shots per competition, forwards and midfielders had significantly higher number of shots than defenders. Shot accuracy was about 31%; midfielders and forwards had significantly higher shot accuracy than defenders. Forwards showed significantly lower ball interception and higher ball losses than other positions. Conclusion : The result of this study showed that there were significant differences between some technical actions in positional roles. Therefore, coaches can use this information for individualization of training according to playing positions and for optimization of training in the amateur game.

Analysis of Invasion Dynamics of Matrix-Embedded Cells in a Multisample Format.

Science.gov (United States)

Van Troys, Marleen; Masuzzo, Paola; Huyck, Lynn; Bakkali, Karima; Waterschoot, Davy; Martens, Lennart; Ampe, Christophe

2018-01-01

In vitro tests of cancer cell invasion are the "first line" tools of preclinical researchers for screening the multitude of chemical compounds or cell perturbations that may aid in halting or treating cancer malignancy. In order to have predictive value or to contribute to designing personalized treatment regimes, these tests need to take into account the cancer cell environment and measure effects on invasion in sufficient detail. The in vitro invasion assays presented here are a trade-off between feasibility in a multisample format and mimicking the complexity of the tumor microenvironment. They allow testing multiple samples and conditions in parallel using 3D-matrix-embedded cells and deal with the heterogeneous behavior of an invading cell population in time. We describe the steps to take, the technical problems to tackle and useful software tools for the entire workflow: from the experimental setup to the quantification of the invasive capacity of the cells. The protocol is intended to guide researchers to standardize experimental set-ups and to annotate their invasion experiments in sufficient detail. In addition, it provides options for image processing and a solution for storage, visualization, quantitative analysis, and multisample comparison of acquired cell invasion data.

Identification of the Key Fields and Their Key Technical Points of Oncology by Patent Analysis.

Science.gov (United States)

Zhang, Ting; Chen, Juan; Jia, Xiaofeng

2015-01-01

This paper aims to identify the key fields and their key technical points of oncology by patent analysis. Patents of oncology applied from 2006 to 2012 were searched in the Thomson Innovation database. The key fields and their key technical points were determined by analyzing the Derwent Classification (DC) and the International Patent Classification (IPC), respectively. Patent applications in the top ten DC occupied 80% of all the patent applications of oncology, which were the ten fields of oncology to be analyzed. The number of patent applications in these ten fields of oncology was standardized based on patent applications of oncology from 2006 to 2012. For each field, standardization was conducted separately for each of the seven years (2006-2012) and the mean of the seven standardized values was calculated to reflect the relative amount of patent applications in that field; meanwhile, regression analysis using time (year) and the standardized values of patent applications in seven years (2006-2012) was conducted so as to evaluate the trend of patent applications in each field. Two-dimensional quadrant analysis, together with the professional knowledge of oncology, was taken into consideration in determining the key fields of oncology. The fields located in the quadrant with high relative amount or increasing trend of patent applications are identified as key ones. By using the same method, the key technical points in each key field were identified. Altogether 116,820 patents of oncology applied from 2006 to 2012 were retrieved, and four key fields with twenty-nine key technical points were identified, including "natural products and polymers" with nine key technical points, "fermentation industry" with twelve ones, "electrical medical equipment" with four ones, and "diagnosis, surgery" with four ones. The results of this study could provide guidance on the development direction of oncology, and also help researchers broaden innovative ideas and discover new

Analysis Of Human Capital Development In Technical Colleges In ...

African Journals Online (AJOL)

The study assessed the human capital development in Technical Colleges in Imo State of Nigeria. All the Technical Colleges in the State participated in the study. Results showed low enrollment in the Colleges. There was gender inequity in the enrollment as only 59 females (1.97%) enrolled in the Technical Colleges.

CALS Baseline Architecture Analysis of Weapons System. Technical Information: Army, Draft. Volume 8

Science.gov (United States)

1989-09-01

This effort was performed to provide a common framework for analysis and planning of CALS initiatives across the military services, leading eventually to the development of a common DoD-wide architecture for CALS. This study addresses Army technical ...

Modeling technical efficiency of inshore fishery using data envelopment analysis

Science.gov (United States)

Rahman, Rahayu; Zahid, Zalina; Khairi, Siti Shaliza Mohd; Hussin, Siti Aida Sheikh

2016-10-01

Fishery industry contributes significantly to the economy of Malaysia. This study utilized Data Envelopment Analysis application in estimating the technical efficiency of fishery in Terengganu, a state on the eastern coast of Peninsular Malaysia, based on multiple output, i.e. total fish landing and income of fishermen with six inputs, i.e. engine power, vessel size, number of trips, number of workers, cost and operation distance. The data were collected by survey conducted between November and December 2014. The decision making units (DMUs) involved 100 fishermen from 10 fishery areas. The result showed that the technical efficiency in Season I (dry season) and Season II (rainy season) were 90.2% and 66.7% respectively. About 27% of the fishermen were rated to be efficient during Season I, meanwhile only 13% of the fishermen achieved full efficiency 100% during Season II. The results also found out that there was a significance difference in the efficiency performance between the fishery areas.

49 CFR 552.6 - Technical review.

Science.gov (United States)

2010-10-01

... 49 Transportation 6 2010-10-01 2010-10-01 false Technical review. 552.6 Section 552.6... § 552.6 Technical review. The appropriate Associate Administrator conducts a technical review of the petition. The technical review may consist of an analysis of the material submitted, together with...

Formal Modelling and Analysis of Socio-Technical Systems

NARCIS (Netherlands)

Probst, Christian W.; Kammüller, Florian; Rydhof Hansen, René; Probst, Christian W.; Hankin, Chris; Rydhof Hansen, René

2015-01-01

Attacks on systems and organisations increasingly exploit human actors, for example through social engineering. This non-technical aspect of attacks complicates their formal treatment and automatic identification. Formalisation of human behaviour is difficult at best, and attacks on socio-technical

Technical Considerations for the Generation of Adoptively Transferred T Cells in Cancer Immunotherapy

Directory of Open Access Journals (Sweden)

Anthony Visioni

2016-09-01

Full Text Available A significant function of the immune system is the surveillance and elimination of aberrant cells that give rise to cancer. Even when tumors are well established and metastatic, immune-mediated spontaneous regressions have been documented. While there are have been various forms of immunotherapy, one of the most widely studied for almost 40 years is adoptive cellular immunotherapy, but its success has yet to be fully realized. Adoptive cell transfer (ACT is a therapeutic modality that has intrigued physicians and researchers for its many theoretical benefits. Preclinical investigations and human trials have utilized natural killer (NK cells, dendritic cells (DC, macrophages, T-cells or B-cells for ACT with the most intense research focused on T-cell ACT. T-cells are exquisitely specific to the target of its T-cell receptor (TCR, thus potentially reducing the amount of collateral damage and off-target effects from treatment. T-cells also possess a memory subset that may reduce the risk of recurrence of a cancer after the successful treatment of the primary disease. There are several options for the source of T-cells used in the generation of cells for ACT. Perhaps the most widely known source is T-cells generated from tumor-infiltrating lymphocytes (TILs. However, studies have also employed peripheral blood mononuclear cells (PBMCs, lymph nodes, and even induced pluripotent stem cells (IPSCs as a source of T-cells. Several important technical considerations exist regarding benefits and limitations of each source of T-cells. Unique aspects of T-cells factor into their ability to be efficacious in ACT including the total number of cells available for ACT, the anti-tumor efficacy on a per cell basis, the repertoire of TCRs specific to tumor cells, and their ability to traffic to various organs that harbor tumor. Current research is attempting to unlock the full potential of these cells to effectively and safely treat cancer.

Technical and Economic Analysis of a Hybrid Generation System of Wind Turbines, Photovoltaic Modules and a Fuel Cell

OpenAIRE

Szczerbowsk Radosław; Ceran Bartosz

2016-01-01

The paper presents the results of the analysis of the economic and manufacturing system consisting of wind turbines, photovoltaic modules, polymer membrane fuel cell and the electrolyzer. The system supplies the customer profile at the assumed wind and solar conditions. Energy analysis was conducted on the basis of the balance equations produced and received electric power. To assess the economic efficiency of investments adopted the following economic indicators: NPV, IRR, MIRR, MNPV, DPP. T...

Fuel Cell Technology Status Analysis | Hydrogen and Fuel Cells | NREL

Science.gov (United States)

Technology Status Analysis Fuel Cell Technology Status Analysis Get Involved Fuel cell developers interested in collaborating with NREL on fuel cell technology status analysis should send an email to NREL's Technology Validation Team at techval@nrel.gov. NREL's analysis of fuel cell technology provides objective

Automated Analysis of Flow Cytometry Data to Reduce Inter-Lab Variation in the Detection of Major Histocompatibility Complex Multimer-Binding T Cells

DEFF Research Database (Denmark)

Pedersen, Natasja Wulff; Chandran, P. Anoop; Qian, Yu

2017-01-01

Manual analysis of flow cytometry data and subjective gate-border decisions taken by individuals continue to be a source of variation in the assessment of antigen-specific T cells when comparing data across laboratories, and also over time in individual labs. Therefore, strategies to provide...... automated analysis of major histocompatibility complex (MHC) multimer-binding T cells represent an attractive solution to decrease subjectivity and technical variation. The challenge of using an automated analysis approach is that MHC multimer-binding T cell populations are often rare and therefore...... laboratories. We used three different methods, FLOw Clustering without K (FLOCK), Scalable Weighted Iterative Flow-clustering Technique (SWIFT), and ReFlow to analyze flow cytometry data files from 28 laboratories. Each laboratory screened for antigen-responsive T cell populations with frequency ranging from 0...

DISPOWER. A socio-economic analysis of technical solutions and practices for the integration of distributed generation

International Nuclear Information System (INIS)

Ten Donkelaar, M.; Scheepers, M.J.J.

2004-07-01

Socio-economic impacts of technical solutions and approaches that are being developed for the integration of distributed generation (DG) in electricity distribution systems are analyzed. For this analysis an inventory was made of technical options, solutions and approaches on the basis of a questionnaire that has been distributed among DG (technical) experts. The questionnaire was not meant to give an exhaustive overview, but to gain insight in the possible technical solutions, options and approaches and the economic interactions between different actors in the electricity market. The different technical options and solutions have been divided into four main categories. Four technologies, one of each category, have been studied in more detail to analyse their impact on the financial relationships between the actors in the distribution network. The four technologies are: wind power prediction tool (planning tool), grid control unit (power quality device), power operation and power quality management system (ICT device), and power storage device. To assess the impact of the investments in the proposed technologies on all actors involved (and different from the actor investing), an assessment tool has been developed to qualitatively identify the economic impacts of a number of these options. This assessment tool takes into account the financial transactions between the parties on the distribution network. The analysis also discusses the allocation of the economic value of certain benefits through contracts and economic network regulation

Exploring the relationship between anaesthesiologists' non-technical and technical skills

DEFF Research Database (Denmark)

Gjeraa, K; Jepsen, R M H G; Rewers, M

2016-01-01

BACKGROUND: A combination of non-technical skills (NTS) and technical skills (TS) is crucial for anaesthetic patient management. However, a deeper understanding of the relationship between these two skills remains to be explored. We investigated the characteristics of trainee anaesthesiologists...... the customised version of the Anaesthetists' Non-Technical Skills System, ANTSdk, and an adapted TS checklist for calculating the correlation between NTS and TS. Written descriptions of the observed NTS were analysed using directed content analysis. RESULTS: The correlation between the NTS and the TS ratings......, concrete NTS were developed to aid the understanding, training and use of NTS....

Technical Skill Attainment and Post-Program Outcomes: An Analysis of Pennsylvania Secondary Career and Technical Education Graduates

Science.gov (United States)

Staklis, Sandra; Klein, Steven

2010-01-01

Since the mid-1990s, the Pennsylvania Department of Education (PDE) has required all students concentrating in career and technical education (CTE) programs to complete a standardized technical skill assessment at or near the end of their program. Results of technical skill assessments are used for a number of purposes, including recognizing…

Technical development and economic valuation of new cooling methods for planar solid oxide fuel cells (SOFC)

International Nuclear Information System (INIS)

Thom, F.

2002-02-01

A great potential exists for the use of the solid oxide fuel cell technology based on the planar cell design concept. Besides its application as power provider there is a need to supply process heat in the temperature range of 200 to 1200 C for commercial and industrial decentralized facilities. The present study is concerned with the technical development and economic valuation of plant concepts of new fuel cell cooling methods. They can be considered as an alternative to the normal convective cell cooling with air. Besides experimental studies on the natural gas reforming with the SOFC special attention is paid to the process analysis of the power plant carried out with the simulating program PROII. The 200 kWe SOFC is linked with peripheral components such as prereformer, heat exchangers, compressors etc. Developed program subroutine serve to calculate the electrical power output of the fuel cell, the investment costs and the costs of electricity. The study shows clearly that a radiative cell cooling device on basis of an external arranged vaporizer has economic benefits in comparison with the normal air cooling. In this case the possibility is given to run the fuel cell with completely prereformed natural gas. When the internal methane reforming is carried out in excess of the electrochemical demand for hydrogen and carbon monoxide respectively a further cost reduction potential is given. The produced synthesis gas can be used in alternative to the production of power in a gas turbine to supply process steam in the temperature range of 200 to 1200 C. Sensitivity analyses show that a successive use of optimization potentials (e.g. anode structure and operating parameters of the SOFC) leads to a further reduction of the costs of electricity. In the best case the achieved costs of 12 to 13 Pf/kWh are in a range achieved by CHP plants based on engines. (orig.) [de

Single Cell and Metagenomic Assemblies: Biology Drives Technical Choices and Goals (Metagenomics Informatics Challenges Workshop: 10K Genomes at a Time)

Energy Technology Data Exchange (ETDEWEB)

Stepanauskas, Ramunas

2011-10-13

DOE JGI's Tanja Woyke, chair of the Single Cells and Metagenomes session, delivers an introduction, followed by Bigelow Laboratory's Ramunas Stepanauskas on "Single Cell and Metagenomic Assemblies: Biology Drives Technical Choices and Goals" at the Metagenomics Informatics Challenges Workshop held at the DOE JGI on October 12-13, 2011.

Reduce the risk of stock trading by using technical analysis in iran's ...

African Journals Online (AJOL)

Reduce the risk of stock trading by using technical analysis in iran's stock market. ... In this research, efficiency of 50 active companies of Tehran Stock ... With this observation, this research suggest forming a portfolio with zero cost by purchasing ... FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use ...

[A case of the fatal injury by technical electricity from a mobile device (cell phone) connected to the circuit].

Science.gov (United States)

Rudenko, I A; Kil'dyushov, E M; Koludarova, E M; Morozov, V Yu; Fetisov, V A

2015-01-01

The authors report a case of the fatal injury by technical electricity from a mobile device (cell phone) attached to the circuit in a moist environment as a result of the unsafe handling of the gadget (when taking the bath).

ANALYSIS OF EXISTING AND PROSPECTIVE TECHNICAL CONTROL SYSTEMS OF NUMERIC CODES AUTOMATIC BLOCKING

Directory of Open Access Journals (Sweden)

A. M. Beznarytnyy

2013-09-01

Full Text Available Purpose. To identify the characteristic features of the engineering control measures system of automatic block of numeric code, identifying their advantages and disadvantages, to analyze the possibility of their use in the problems of diagnosing status of the devices automatic block and setting targets for the development of new diagnostic systems. Methodology. In order to achieve targets the objective theoretical and analytical method and the method of functional analysis have been used. Findings. The analysis of existing and future facilities of the remote control and diagnostics automatic block devices had shown that the existing systems of diagnosis were not sufficiently informative, designed primarily to control the discrete parameters, which in turn did not allow them to construct a decision support subsystem. In developing of new systems of technical diagnostics it was proposed to use the principle of centralized distributed processing of diagnostic data, to include a subsystem support decision-making in to the diagnostics system, it will reduce the amount of work to maintain the devices blocking and reduce recovery time after the occurrence injury. Originality. As a result, the currently existing engineering controls facilities of automatic block can not provide a full assessment of the state distillation alarms and locks. Criteria for the development of new systems of technical diagnostics with increasing amounts of diagnostic information and its automatic analysis were proposed. Practical value. These results of the analysis can be used in practice in order to select the technical control of automatic block devices, as well as the further development of diagnostic systems automatic block that allows for a gradual transition from a planned preventive maintenance service model to the actual state of the monitored devices.

Multiparameter Cell Cycle Analysis.

Science.gov (United States)

Jacobberger, James W; Sramkoski, R Michael; Stefan, Tammy; Woost, Philip G

2018-01-01

Cell cycle cytometry and analysis are essential tools for studying cells of model organisms and natural populations (e.g., bone marrow). Methods have not changed much for many years. The simplest and most common protocol is DNA content analysis, which is extensively published and reviewed. The next most common protocol, 5-bromo-2-deoxyuridine S phase labeling detected by specific antibodies, is also well published and reviewed. More recently, S phase labeling using 5'-ethynyl-2'-deoxyuridine incorporation and a chemical reaction to label substituted DNA has been established as a basic, reliable protocol. Multiple antibody labeling to detect epitopes on cell cycle regulated proteins, which is what this chapter is about, is the most complex of these cytometric cell cycle assays, requiring knowledge of the chemistry of fixation, the biochemistry of antibody-antigen reactions, and spectral compensation. However, because this knowledge is relatively well presented methodologically in many papers and reviews, this chapter will present a minimal Methods section for one mammalian cell type and an extended Notes section, focusing on aspects that are problematic or not well described in the literature. Most of the presented work involves how to segment the data to produce a complete, progressive, and compartmentalized cell cycle analysis from early G1 to late mitosis (telophase). A more recent development, using fluorescent proteins fused with proteins or peptides that are degraded by ubiquitination during specific periods of the cell cycle, termed "Fucci" (fluorescent, ubiquitination-based cell cycle indicators) provide an analysis similar in concept to multiple antibody labeling, except in this case cells can be analyzed while living and transgenic organisms can be created to perform cell cycle analysis ex or in vivo (Sakaue-Sawano et al., Cell 132:487-498, 2007). This technology will not be discussed.

Evaluation of Technical Efficiency in Indian Sugar Industry: An Application of Full Cumulative Data Envelopment Analysis

Directory of Open Access Journals (Sweden)

Sunil KUMAR

2012-05-01

Full Text Available This study focuses on the inter-temporal and inter-state variations in technical and scale efficiency levels of Indian sugar industry. In the first stage, full cumulative data envelopment analysis (FCDEA is used to derive efficiency scores for 12 major sugar producing states. The panel data truncated regression is employed in the second stage to assess the key factors explaining the observed variations in the efficiency levels. The results suggest that the extent of technical inefficiency in Indian sugar industry is about 35.5 percent per annum, and the observed technical inefficiency stems primarily due to managerial inefficiency rather scale inefficiency. Also, a precipitous decline in the level of technical efficiency has been noticed in the postreforms period relative to the level observed in the pre-reforms period. The availability of skilled labour and profitability have been found to be most significant determinants of technical efficiency in Indian sugar industry.

Single-cell analysis of ploidy and centrosomes underscores the peculiarity of normal hepatocytes.

Directory of Open Access Journals (Sweden)

Francesca Faggioli

Full Text Available Polyploidization is the most well recognized feature of the liver. Yet, a quantitative and behavioral analysis of centrosomes and DNA content in normal hepatocytes has been limited by the technical challenges of methods available. By using a novel approach employing FISH for chromosomes 18, X and Y we provide, for the first time, a detailed analysis of DNA copies during physiological development in the liver at single cell level. We demonstrate that aneuploidy and unbalanced DNA content in binucleated hepatocytes are common features in normal adult liver. Despite the common belief that hepatocytes contain 1, 2 or no more than 4 centrosomes, our double staining for centrosome associated proteins reveals extranumerary centrosomes in a high percentage of cells as early as 15 days of age. We show that in murine liver the period between 15 days and 1.5 months marks the transition from a prevalence of mononucleated cells to up to 75% of binucleated cells. Our data demonstrate that this timing correlates with a switch in centrosomes number. At 15 days the expected 1 or 2 centrosomes converge with several hepatocytes that contain 3 centrosomes; at 1.5 months the percentage of cells with 3 centrosomes decreases concomitantly with the increase of cells with more than 4 centrosomes. Our analysis shows that the extranumerary centrosomes emerge in concomitance with the process of binucleation and polyploidization and maintain α-tubulin nucleation activity. Finally, by integrating interphase FISH and immunofluorescent approaches, we detected an imbalance between centrosome number and DNA content in liver cells that deviates from the equilibrium expected in normal cells. We speculate that these unique features are relevant to the peculiar biological function of liver cells which are continuously challenged by stress, a condition that could predispose to genomic instability.

Integrated corridor management initiative : demonstration phase evaluation, San Diego technical capability analysis test plan.

Science.gov (United States)

2012-08-01

This report presents the test plan for conducting the Technical Capability Analysis for the United States Department of Transportation (U.S. DOT) evaluation of the San Diego Integrated Corridor Management (ICM) Initiative Demonstration. The ICM proje...

Technical efficiency of Spanish electrical sector: analysis of 1998-2001 period

International Nuclear Information System (INIS)

Gutierrez Moya, E.; Arevalo Quijada, M. T.

2007-01-01

The aim of this article is to analyse the technical efficiency of the energy Spanish sector in the course of the stage of liberalization (1998-2001). The study uses the non parametric approach of DEA (Data Envelopment Analysis) to derive Malaquist productivity indexes. In the study there is revealed the improvement of productivity of the mentioned companies, as well as the major differentiation between electrical considered companies. (Author) 23 refs

Technical and economic analysis of a 1mw grid-connected solar photovoltaic power system at KNUST-Kumasi

International Nuclear Information System (INIS)

Nyarko Kumi, Ebenezer

2012-09-01

Grid-connected solar PV systems, though the fastest growing renewable energy technology in the world, have not been fully exploited in Africa; one of the reasons being the very high initial investment. Prices of solar PV systems have however been on a decline for the past few years due to technological innovations which have led to improvements in cell efficiencies and the economies of scale resulting from increase in production. The main purpose of this thesis is to present a technical and economic analysis of a 1MW grid-connected solar photovoltaic power system for the Kwame Nkrumah University of Science and Technology (KNUST), Kumasi using rooftops of buildings on the campus. A solar resource assessment done to know the amount of solar radiation available at KNUST showed that KNUST receives about 4.30kWh/m 2 /day. A roof assessment which considered parameters such as the surface orientation and pitch of roofs, roof area and the possibility of shading of the roof, also revealed there is about 43,697m 2 of roof space available for grid-connected solar PV installations. In technical analysis of the 1MWp solar PV system, the three (3) commonest solar PV module technologies were selected and their performance simulated using PVsyst software. Amorphous silicon modules were found to perform better than monocrystalline and polycrystalline modules over the one (1) year simulation period. The financial analysis carried out using RETScreen revealed that at a solar PV market price of US$4.45/Wp and a tariff of US$0.11/kWh (tariff paid for Asogli Power Plant which happens to be the most expensive generation source in the country), the project is not viable unless feed-in tariffs greater than US$0.43/kWh are paid. (au)

Microfluidics for single cell analysis

DEFF Research Database (Denmark)

Jensen, Marie Pødenphant

Isolation and manipulation of single cells have gained an increasing interest from researchers because of the heterogeneity of cells from the same cell culture. Single cell analysis can ensure a better understanding of differences between individual cells and potentially solve a variety of clinical...... problems. In this thesis lab on a chip systems for rare single cell analysis are investigated. The focus was to develop a commercial, disposable device for circulating tumour cell (CTC) analysis. Such a device must be able to separate rare cells from blood samples and subsequently capture the specific...... cells, and simultaneously be fabricated and operated at low costs and be user-friendly. These challenges were addressed through development of two microfluidic devices, one for rare cell isolation based on pinched flow fractionation (PFF) and one for single cell capture based on hydrodynamic trapping...

Meta-analysis of the technical performance of an imaging procedure: guidelines and statistical methodology.

Science.gov (United States)

Huang, Erich P; Wang, Xiao-Feng; Choudhury, Kingshuk Roy; McShane, Lisa M; Gönen, Mithat; Ye, Jingjing; Buckler, Andrew J; Kinahan, Paul E; Reeves, Anthony P; Jackson, Edward F; Guimaraes, Alexander R; Zahlmann, Gudrun

2015-02-01

Medical imaging serves many roles in patient care and the drug approval process, including assessing treatment response and guiding treatment decisions. These roles often involve a quantitative imaging biomarker, an objectively measured characteristic of the underlying anatomic structure or biochemical process derived from medical images. Before a quantitative imaging biomarker is accepted for use in such roles, the imaging procedure to acquire it must undergo evaluation of its technical performance, which entails assessment of performance metrics such as repeatability and reproducibility of the quantitative imaging biomarker. Ideally, this evaluation will involve quantitative summaries of results from multiple studies to overcome limitations due to the typically small sample sizes of technical performance studies and/or to include a broader range of clinical settings and patient populations. This paper is a review of meta-analysis procedures for such an evaluation, including identification of suitable studies, statistical methodology to evaluate and summarize the performance metrics, and complete and transparent reporting of the results. This review addresses challenges typical of meta-analyses of technical performance, particularly small study sizes, which often causes violations of assumptions underlying standard meta-analysis techniques. Alternative approaches to address these difficulties are also presented; simulation studies indicate that they outperform standard techniques when some studies are small. The meta-analysis procedures presented are also applied to actual [18F]-fluorodeoxyglucose positron emission tomography (FDG-PET) test-retest repeatability data for illustrative purposes. © The Author(s) 2014 Reprints and permissions: sagepub.co.uk/journalsPermissions.nav.

A Socio-technical Mapping and Analysis of Dominant Design Materialization

DEFF Research Database (Denmark)

Christiansen, John K.; Varnes, Claus

the importance of high market shares for defining a wining dominating design, but despite the electric vehicle’s higher market share in the years 1899-1900 it was surpassed by the internal combustion vehicle. The socio-technical analysis departs from a narrative based on historical accounts on the competition...... between the electric vehicle and the internal combustion vehicle from late 1890 - until 1909. The analysis shows that the electric vehicle did not successfully attract new allies or overcome resistance from anti-programs to the same degree as the internal combustion vehicle. Findings suggest that some...... of the issues with few allies and anti-programs that emerged already during the late 1890'ties is still active in today's market and haunts the electric vehicle....

Comparative analysis of technical efficiency for different production culture systems and species of freshwater aquaculture in Peninsular Malaysia

Directory of Open Access Journals (Sweden)

Abdullahi Iliyasu

2016-05-01

Full Text Available This study estimated the bias-corrected technical efficiency (BCTE of different culture systems and species of freshwater aquaculture in Malaysia using bootstrapping data envelopment analysis (DEA. Data were collected from 307 respondents from three states in Peninsular Malaysia using a well-structured questionnaire as well as oral interviews. The findings indicate that all technical efficiency scores for all culture systems and species are below the optimal level (i.e. one. In addition, the results show that farmers’ experience, contact with extension workers and household size have a positive and statistically significant impact on technical efficiency. This implies that farmers who have long tenure in fish farming and also the opportunity to meet with extension workers are operating close to the production frontier (technically efficient. On the other hand, the age of the farmers has a negative and statistically significant impact on technical efficiency. Although educational level and farm status have a positive impact on technical efficiency, they are statistically insignificant. Furthermore, all the inputs used in the production process of different culture systems and species contained slacks and need to be reduced accordingly. Feed, the major input in fish production and constituting over half of the production costs, is equally over-utilized. Thus, the government, in collaboration with research institutes and universities, should design a feeding formula for fish depending on species, culture systems and stages of growth. This could help to reduce production costs, increasing the farmers' income, as well as providing much needed animal protein to consumers at an affordable rate. Keywords: Bootstrapping data envelopment analysis (DEA, Technical efficiency, Technical inefficiency, Freshwater aquaculture, Malaysia

NASA Technical Interchange Meeting (TIM): Advanced Technology Lifecycle Analysis System (ATLAS) Technology Tool Box

Science.gov (United States)

ONeil, D. A.; Craig, D. A.; Christensen, C. B.; Gresham, E. C.

2005-01-01

The objective of this Technical Interchange Meeting was to increase the quantity and quality of technical, cost, and programmatic data used to model the impact of investing in different technologies. The focus of this meeting was the Technology Tool Box (TTB), a database of performance, operations, and programmatic parameters provided by technologists and used by systems engineers. The TTB is the data repository used by a system of models known as the Advanced Technology Lifecycle Analysis System (ATLAS). This report describes the result of the November meeting, and also provides background information on ATLAS and the TTB.

A technical analysis of the IAEA nuclear safeguards

International Nuclear Information System (INIS)

Yoon, J. W.

1998-01-01

In the post-Cold War era, the threats of horizontal nuclear proliferation emerge as the forefront security issue while the nuclear arms races among existing nuclear weapon states reduce to a remarkable extent. In this context, there arises lots of research attention to the IAEA nuclear safeguards which have been viewed as the core of international monitoring on the clandestine nuclear activities of potential proliferators. However, previous attention tended to highlight the political aspects of the IAEA nuclear safeguards, centering on the possibilities and limitations of the IAEA's inspection authority. In contrast, this paper purports to focus on the technical aspects of the IAEA nuclear safeguards, so it can show the intrinsic problems of those safeguards in stemming the proliferation of nuclear weapons. This paper mainly deals with the technical objectives and options of the IAEA nuclear safeguards, the technical indices of clandestine nuclear activities, and some measures to improve the efficacy of the IAEA nuclear safeguards. Hopefully, this paper is expected to lead us to approach the issue of the North Korean nuclear transparency from the technical perspective as well as the political one

Technical Efficiency Analysis of Container Terminals in the Middle Eastern Region

Directory of Open Access Journals (Sweden)

Ebrahim Sharaf Almawsheki

2015-12-01

Full Text Available Despite an increasing number of studies on the efficiency of container terminals, their focus has mostly been on advanced and emerging markets. There are limited studies on container terminals in developing countries such as those of the Middle Eastern region, which are located in a critical geographic position in the international maritime route between the East and the West. Information on their potential for development relative to other terminals worldwide is thus not readily available. This study aims to evaluate the technical efficiency of 19 container terminals in the Middle Eastern region. The DEA approach is used to measure technical efficiency, and slack variable analysis identifies potential areas of improvement for inefficient terminals. The results show that the Jebel Ali, Salalah and Beirut container terminals are the most efficient terminals in the region, and that the least efficient is the terminal in Aden. The results provide valuable information for terminal managers, helping to develop resource utilisation for steady development in operational efficiency.

Structural Analysis of Technical-Tactical Elements in Table Tennis and their Role in Different Playing Zones.

Science.gov (United States)

Munivrana, Goran; Petrinović, Lidija Zekan; Kondrič, Miran

2015-09-29

For the purpose of determining the overall structure of technical-tactical elements in table tennis and evaluating their role in different playing zones around the table, a new measuring instrument (a questionnaire) was formulated that took advantage of the expert knowledge of top, world class table tennis coaches. The results of the hierarchical taxonomic (cluster) analysis showed that the overall structure of the technical-tactical elements forming the table tennis technique could be divided into three basic groups; a group of technical-tactical elements (A) used in the phase of preparing one's own and disabling the opponent's attack; a group of technical-tactical elements (B) used in the phase of attack and counterattack; and a group of technical-tactical elements (C) used in the phase of defense. The differences among the obtained groups of table tennis elements were determined by applying the Kruskal-Wallis test, while relations between the groups and their role in different playing zones around the table were analyzed by comparing the average values of the experts' scores.

Structural Analysis of Technical-Tactical Elements in Table Tennis and their Role in Different Playing Zones

Directory of Open Access Journals (Sweden)

Munivrana Goran

2015-09-01

Full Text Available For the purpose of determining the overall structure of technical-tactical elements in table tennis and evaluating their role in different playing zones around the table, a new measuring instrument (a questionnaire was formulated that took advantage of the expert knowledge of top, world class table tennis coaches. The results of the hierarchical taxonomic (cluster analysis showed that the overall structure of the technical-tactical elements forming the table tennis technique could be divided into three basic groups; a group of technical-tactical elements (A used in the phase of preparing one’s own and disabling the opponent’s attack; a group of technical-tactical elements (B used in the phase of attack and counterattack; and a group of technical-tactical elements (C used in the phase of defense. The differences among the obtained groups of table tennis elements were determined by applying the Kruskal-Wallis test, while relations between the groups and their role in different playing zones around the table were analyzed by comparing the average values of the experts’ scores.

Medium Term Analysis of Technical and Allocative Efficiency in Romanian Farms Using FADN Dataset

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Nicola GALLUZZO

2017-05-01

Full Text Available The Farm Accountancy Data Network is an annual survey proposed by the European Union in order to estimate the impact of the Common Agricultural Policy on farmers. Lots of scholars have investigated the technical, economical and allocative efficiency using a non parametric approach such as the Data Envelopment Analysis (DEA in Romanian farms throughout the Farm Accountancy Data Network dataset pointing out poor levels of technical efficiency, which were lower than the average European value. The purpose of this study was to assess using DEA approach technical, economic and allocative efficiency in Romanian farms part of the FADN dataset over six year time from 2007 to 2012. Findings pointed out an increase of technical efficiency compared to previous studies, as a consequence of a significant turn over of a younger high skill and qualified farmers generation. Poor land capital, in terms of utilized agricultural areas, connected to an increase of new technologies, was the downside of Romanian farms and this implied that the National Rural Development Plan should  have taken into account financial subsides in order to implement agricultural areas scattered in Romanian rural space.

Technical Agency in Practice

DEFF Research Database (Denmark)

Krummheuer, Antonia Lina

2015-01-01

) description of hybrid networks in which human and non-human actants are granted agency without differentiating different kinds of agency, EMCA focuses on the member's perspectives and the situated construction of technical agency that is made relevant within an ongoing interaction. Based on an EMCA analysis......The paper combines the discussion of technical agency and hybrid networks of Actor-Network Theory (ANT) with an ethnomethodological/conversation analytical (EMCA) perspective on situated practices in which participants ascribe agency to technical artefacts. While ANT works with (ethnographic...... of three video recordings of situations in which technical agency is made relevant by the human participants, the paper demonstrates different ways in which agency is granted to technical artefacts. Human participants can treat a technology as communication partner, as an active part (and actant...

Ownership and technical efficiency of hospitals: evidence from Ghana using data envelopment analysis.

Science.gov (United States)

Jehu-Appiah, Caroline; Sekidde, Serufusa; Adjuik, Martin; Akazili, James; Almeida, Selassi D; Nyonator, Frank; Baltussen, Rob; Asbu, Eyob Zere; Kirigia, Joses Muthuri

2014-04-08

In order to measure and analyse the technical efficiency of district hospitals in Ghana, the specific objectives of this study were to (a) estimate the relative technical and scale efficiency of government, mission, private and quasi-government district hospitals in Ghana in 2005; (b) estimate the magnitudes of output increases and/or input reductions that would have been required to make relatively inefficient hospitals more efficient; and (c) use Tobit regression analysis to estimate the impact of ownership on hospital efficiency. In the first stage, we used data envelopment analysis (DEA) to estimate the efficiency of 128 hospitals comprising of 73 government hospitals, 42 mission hospitals, 7 quasi-government hospitals and 6 private hospitals. In the second stage, the estimated DEA efficiency scores are regressed against hospital ownership variable using a Tobit model. This was a retrospective study. In our DEA analysis, using the variable returns to scale model, out of 128 district hospitals, 31 (24.0%) were 100% efficient, 25 (19.5%) were very close to being efficient with efficiency scores ranging from 70% to 99.9% and 71 (56.2%) had efficiency scores below 50%. The lowest-performing hospitals had efficiency scores ranging from 21% to 30%.Quasi-government hospitals had the highest mean efficiency score (83.9%) followed by public hospitals (70.4%), mission hospitals (68.6%) and private hospitals (55.8%). However, public hospitals also got the lowest mean technical efficiency scores (27.4%), implying they have some of the most inefficient hospitals.Regarding regional performance, Northern region hospitals had the highest mean efficiency score (83.0%) and Volta Region hospitals had the lowest mean score (43.0%).From our Tobit regression, we found out that while quasi-government ownership is positively associated with hospital technical efficiency, private ownership negatively affects hospital efficiency. It would be prudent for policy-makers to examine the

[Analysis of the technical efficiency of hospitals in the Spanish National Health Service].

Science.gov (United States)

Pérez-Romero, Carmen; Ortega-Díaz, M Isabel; Ocaña-Riola, Ricardo; Martín-Martín, José Jesús

To analyse the technical efficiency and productivity of general hospitals in the Spanish National Health Service (NHS) (2010-2012) and identify explanatory hospital and regional variables. 230 NHS hospitals were analysed by data envelopment analysis for overall, technical and scale efficiency, and Malmquist index. The robustness of the analysis is contrasted with alternative input-output models. A fixed effects multilevel cross-sectional linear model was used to analyse the explanatory efficiency variables. The average rate of overall technical efficiency (OTE) was 0.736 in 2012; there was considerable variability by region. Malmquist index (2010-2012) is 1.013. A 23% variability in OTE is attributable to the region in question. Statistically significant exogenous variables (residents per 100 physicians, aging index, average annual income per household, essential public service expenditure and public health expenditure per capita) explain 42% of the OTE variability between hospitals and 64% between regions. The number of residents showed a statistically significant relationship. As regards regions, there is a statistically significant direct linear association between OTE and annual income per capita and essential public service expenditure, and an indirect association with the aging index and annual public health expenditure per capita. The significant room for improvement in the efficiency of hospitals is conditioned by region-specific characteristics, specifically aging, wealth and the public expenditure policies of each one. Copyright © 2016 SESPAS. Publicado por Elsevier España, S.L.U. All rights reserved.

Meta-Analysis as a Choice to Improve Research in Career and Technical Education

Science.gov (United States)

Gordon, Howard R. D.; McClain, Clifford R.; Kim, Yeonsoo; Maldonado, Cecilia

2010-01-01

A search of the ERIC and Academic Search Premier data bases, and a comprehensive review of literature suggest that meta-analysis is ignored by career and technical education (CTE) researchers, a situation that is regrettable but remediable. The purpose of this theoretical paper is to provide CTE researchers and consumers with procedures for…

Simulation analysis for integrated evaluation of technical and commercial risk

International Nuclear Information System (INIS)

Gutleber, D.S.; Heiberger, E.M.; Morris, T.D.

1995-01-01

Decisions to invest in oil- and gasfield acquisitions or participating interests often are based on the perceived ability to enhance the economic value of the underlying asset. A multidisciplinary approach integrating reservoir engineering, operations and drilling, and deal structuring with Monte Carlo simulation modeling can overcome weaknesses of deterministic analysis and significantly enhance investment decisions. This paper discusses the use of spreadsheets and Monte Carlo simulation to generate probabilistic outcomes for key technical and economic parameters for ultimate identification of the economic volatility and value of potential deal concepts for a significant opportunity. The approach differs from a simple risk analysis for an individual well by incorporating detailed, full-field simulations that vary the reservoir parameters, capital and operating cost assumptions, and schedules on timing in the framework of various deal structures

Technical and Economic Analysis of a Hybrid Generation System of Wind Turbines, Photovoltaic Modules and a Fuel Cell

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Szczerbowsk Radosław

2016-01-01

Full Text Available The paper presents the results of the analysis of the economic and manufacturing system consisting of wind turbines, photovoltaic modules, polymer membrane fuel cell and the electrolyzer. The system supplies the customer profile at the assumed wind and solar conditions. Energy analysis was conducted on the basis of the balance equations produced and received electric power. To assess the economic efficiency of investments adopted the following economic indicators: NPV, IRR, MIRR, MNPV, DPP. The authors describe the limits of investment costs intended for the construction, which use hybrid power generation system (HPGS is viable.

Technical writing versus technical writing

Science.gov (United States)

Dillingham, J. W.

1981-01-01

Two terms, two job categories, 'technical writer' and 'technical author' are discussed in terms of industrial and business requirements and standards. A distinction between 'technical writing' and technical 'writing' is made. The term 'technical editor' is also considered. Problems inherent in the design of programs to prepare and train students for these jobs are discussed. A closer alliance between industry and academia is suggested as a means of preparing students with competent technical communication skills (especially writing and editing skills) and good technical skills.

Mechanistic approach to generalized technical analysis of share prices and stock market indices

Science.gov (United States)

Ausloos, M.; Ivanova, K.

2002-05-01

Classical technical analysis methods of stock evolution are recalled, i.e. the notion of moving averages and momentum indicators. The moving averages lead to define death and gold crosses, resistance and support lines. Momentum indicators lead the price trend, thus give signals before the price trend turns over. The classical technical analysis investment strategy is thereby sketched. Next, we present a generalization of these tricks drawing on physical principles, i.e. taking into account not only the price of a stock but also the volume of transactions. The latter becomes a time dependent generalized mass. The notion of pressure, acceleration and force are deduced. A generalized (kinetic) energy is easily defined. It is understood that the momentum indicators take into account the sign of the fluctuations, while the energy is geared toward the absolute value of the fluctuations. They have different patterns which are checked by searching for the crossing points of their respective moving averages. The case of IBM evolution over 1990-2000 is used for illustrations.

Technical Support to an Operating PWR vis-a-vis Safety Analysis

International Nuclear Information System (INIS)

Gul, Subhan; Khan, M.; Chughtai, M. Kamran

2011-01-01

Currently a PWR of 300 MWe capacity CHASNUPP-I is in operation since the year 2000. Technical support being provided includes in-core fuel management and corresponding safety analysis for the reshuffled core for the next cycle. Currently calculation and analysis were performed for Cycle 6 to achieve the safe and economical loading pattern. The technique used is designated as out in mode (modified). In this technique, most of the fresh fuel assemblies are not directly located at the periphery of the core, but near the boundary. This technique has the advantage that without using burnable absorber we can design a low leakage core with extended cycle and maximum batch averaged burnup. (author)

Analysis of the frequency of technical-tactical actions in taekwondo: a review

Directory of Open Access Journals (Sweden)

Paula Avakian

2016-12-01

Full Text Available Taekwondo (TKD is a combat sport, focusing on head-height kicks, spinning kicks and skipping. The emphasis on technical-tactical combinations with speed and agility is an essential characteristic of this modality. Therefore, this review aims to contribute to the critical analysis of technical-tactical actions of TKD athletes, using relative effort and pause moments of official competitions. This review investigated tactical arrangements (i.e., attacks, defenses and blocks, technical performance (points, kicks and punches, regarding to weight category, age class and gender. In fact, rule changes in recent years have increased defensive actions in the senior category, with about 50% of actions in attacks, followed by 30% in defenses and 20% in blocking actions. While juniors tend to adopt an offensive strategy, with about 90% of the actions in attacks. Since the introduction of the scoring electronic system, high-performance athletes need to perform accurate and correct techniques to achieve scoring, so elite athletes have used short-distance techniques with kicks from the back leg. This action shows effectiveness in scoring and assists competitors in increasing defensive capability and counter-attacks. Consequently, training programs need to be specific to the rules, weight divisions, gender and age categories in elite athletes in TKD.

Head Start Impact Study. Technical Report

Science.gov (United States)

Puma, Michael; Bell, Stephen; Cook, Ronna; Heid, Camilla; Shapiro, Gary; Broene, Pam; Jenkins, Frank; Fletcher, Philip; Quinn, Liz; Friedman, Janet; Ciarico, Janet; Rohacek, Monica; Adams, Gina; Spier, Elizabeth

2010-01-01

This Technical Report is designed to provide technical detail to support the analysis and findings presented in the "Head Start Impact Study Final Report" (U.S. Department of Health and Human Services, January 2010). Chapter 1 provides an overview of the Head Start Impact Study and its findings. Chapter 2 provides technical information on the…

Teaching technical writing in multilingual contexts: a meta-analysis

NARCIS (Netherlands)

Winberg, Christine; van der Geest, Thea; Lehman, Barbara; Nduna, Joyce

2010-01-01

Teachers of technical and professional writing in Science, Engineering and Technology (SET) Programmes need to understand the particular needs and social contexts of students for whom English is not a first language. The focus of this paper is on technical writing, and the paper presents the

The technical analysis of the stock exchange and physics: Japanese candlesticks for solar activity

Science.gov (United States)

Dineva, C.; Atanasov, V.

2013-09-01

In this article, we use the Japanese candlesticks, a method popular in the technical analysis of the Stock/Forex markets and apply it to a variable in physics-the solar activity. This method is invented and used exclusively for economic analysis and its application to a physical problem produced unexpected results. We found that the Japanese candlesticks are convenient tool in the analysis of the variables in the physics of the Sun. Based on our observations, we differentiated a new cycle in the solar activity.

Outcomes of Technical Variant Liver Transplantation versus Whole Liver Transplantation for Pediatric Patients: A Meta-Analysis.

Science.gov (United States)

Ye, Hui; Zhao, Qiang; Wang, Yufang; Wang, Dongping; Zheng, Zhouying; Schroder, Paul Michael; Lu, Yao; Kong, Yuan; Liang, Wenhua; Shang, Yushu; Guo, Zhiyong; He, Xiaoshun

2015-01-01

To overcome the shortage of appropriate-sized whole liver grafts for children, technical variant liver transplantation has been practiced for decades. We perform a meta-analysis to compare the survival rates and incidence of surgical complications between pediatric whole liver transplantation and technical variant liver transplantation. To identify relevant studies up to January 2014, we searched PubMed/Medline, Embase, and Cochrane library databases. The primary outcomes measured were patient and graft survival rates, and the secondary outcomes were the incidence of surgical complications. The outcomes were pooled using a fixed-effects model or random-effects model. The one-year, three-year, five-year patient survival rates and one-year, three-year graft survival rates were significantly higher in whole liver transplantation than technical variant liver transplantation (OR = 1.62, 1.90, 1.65, 1.78, and 1.62, respectively, ptechnical variant liver transplantation. Continuing efforts should be made to minimize surgical complications to improve the outcomes of technical variant liver transplantation.

Plant Cell Division Analyzed by Transient Agrobacterium-Mediated Transformation of Tobacco BY-2 Cells.

Science.gov (United States)

Buschmann, Henrik

2016-01-01

The continuing analysis of plant cell division will require additional protein localization studies. This is greatly aided by GFP-technology, but plant transformation and the maintenance of transgenic lines can present a significant technical bottleneck. In this chapter I describe a method for the Agrobacterium-mediated genetic transformation of tobacco BY-2 cells. The method allows for the microscopic analysis of fluorescence-tagged proteins in dividing cells in within 2 days after starting a coculture. This transient transformation procedure requires only standard laboratory equipment. It is hoped that this rapid method would aid researchers conducting live-cell localization studies in plant mitosis and cytokinesis.

Technical findings and regulatory analysis for Generic Safety Issue II.E.4.3, ''Containment Integrity Check''

International Nuclear Information System (INIS)

Serkiz, A.W.

1988-04-01

This report contains the technical findings and regulatory analysis for Generic Safety Issue II.E.4.3, ''Containment Integrity Check.'' An evaluation of the containment isolation history from 1965 to 1983 reveals that (except for a small number of events) containment integrity has been maintained and that the majority of reported events have been events related to exceeding Technical Specification limits (or 0.6 of the allowable leakage level). In addition, more recent risk analyses have shown that allowable leakage rates even if increased by a factor of 10 would not significantly increase risk. Potential methods of continuous monitoring are identified and evaluated. Therefore, these technical findings and risk evaluations support closure of Generic Safety Issue II.E.4.3

Analysis of factors affecting the technical efficiency of cocoa ...

African Journals Online (AJOL)

The study estimated the technical efficiency of cocoa producers and the socioeconomic factors influencing technical efficiency and identified the constraints to cocoa production. A multi-stage random sampling method was used to select 180 cocoa farmers who were interviewed for the study. Data on the inputs used and ...

Data on the putative role of p53 in breast cancer cell adhesion: Technical information for adhesion assay

Directory of Open Access Journals (Sweden)

Kallirroi Voudouri

2016-12-01

Full Text Available In this data article, the potential role of p53 tumor suppressor gene (p53 on the attachment ability of MCF-7 breast cancer cells was investigated. In our main article, “IGF-I/ EGF and E2 signaling crosstalk through IGF-IR conduit point affect breast cancer cell adhesion” (K. Voudouri, D. Nikitovic, A. Berdiaki, D. Kletsas, N.K. Karamanos, G.N. Tzanakakis, 2016 [1], we describe the key role of IGF-IR in breast cancer cell adhesion onto fibronectin (FN. p53 tumor suppressor gene is a principal regulator of cancer cell proliferation. Various data have demonstrated an association between p53 and IGF-IR actions on cell growth through its’ putative regulation of IGF-IR expression. According to our performed experiments, p53 does not modify IGF-IR expression and does not affect basal MCF-7 cells adhesion onto FN. Moreover, technical details about the performance of adhesion assay onto the FN substrate were provided.

Study on the Technical Efficiency of Creative Human Capital in China by Three-Stage Data Envelopment Analysis Model

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Jian Ma

2014-01-01

Full Text Available Previous researches have proved the positive effect of creative human capital and its development on the development of economy. Yet, the technical efficiency of creative human capital and its effects are still under research. The authors are trying to estimate the technical efficiency value in Chinese context, which is adjusted by the environmental variables and statistical noises, by establishing a three-stage data envelopment analysis model, using data from 2003 to 2010. The research results indicate that, in this period, the entirety of creative human capital in China and the technical efficiency value in different regions and different provinces is still in the low level and could be promoted. Otherwise, technical non-efficiency is mostly derived from the scale nonefficiency and rarely affected by pure technical efficiency. The research also examines environmental variables’ marked effects on the technical efficiency, and it shows that different environmental variables differ in the aspect of their own effects. The expansion of the scale of education, development of healthy environment, growth of GDP, development of skill training, and population migration could reduce the input of creative human capital and promote the technical efficiency, while development of trade and institutional change, on the contrary, would block the input of creative human capital and the promotion the technical efficiency.

Secondary Analysis of Audio Data. Technical Procedures for Virtual Anonymization and Pseudonymization

Directory of Open Access Journals (Sweden)

Henning Pätzold

2005-01-01

Full Text Available Qualitative material presented as audio data requires a greater degree of protecting of anonymity than for example textual data. Apart from the verbal content, it carries paraverbal aspects including voice characteristics, thus making it easier to identify the speaker. This complicates secondary analysis or reanalysis conducted by researchers who were not involved in the data collection. Difficulties increase if the chances are high that the researcher and the interviewee come in contact for example through a meeting. This paper describes the technical procedures that are used to modify the sound of the audio source in a way that it reduces the possibility of recognition (i.e. similar to that of a carefully written transcript. A discussion of the technical possibilities of this procedure along with an exploration of the boundaries of anonymization is presented. URN: urn:nbn:de:0114-fqs0501249

[Multilevel analysis of the technical efficiency of hospitals in the Spanish National Health System by property and type of management].

Science.gov (United States)

Pérez-Romero, Carmen; Ortega-Díaz, M Isabel; Ocaña-Riola, Ricardo; Martín-Martín, José Jesús

2018-05-11

To analyze technical efficiency by type of property and management of general hospitals in the Spanish National Health System (2010-2012) and identify hospital and regional explanatory variables. 230 hospitals were analyzed combining data envelopment analysis and fixed effects multilevel linear models. Data envelopment analysis measured overall, technical and scale efficiency, and the analysis of explanatory factors was performed using multilevel models. The average rate of overall technical efficiency of hospitals without legal personality is lower than hospitals with legal personality (0.691 and 0.876 in 2012). There is a significant variability in efficiency under variable returns (TE) by direct, indirect and mixed forms of management. The 29% of the variability in TE es attributable to the Region. Legal personality increased the TE of the hospitals by 11.14 points. On the other hand, most of the forms of management (different to those of the traditional hospitals) increased TE in varying percentages. At regional level, according to the model considered, insularity and average annual income per household are explanatory variables of TE. Having legal personality favours technical efficiency. The regulatory and management framework of hospitals, more than public or private ownership, seem to explain technical efficiency. Regional characteristics explain the variability in TE. Copyright © 2018 SESPAS. Publicado por Elsevier España, S.L.U. All rights reserved.

Analysis of the prevailing standard and technical documents for their applicability under conditions of the 'Ukrytie' operation and technical proposals relating to the elaboration of new ones concerning fire safety

International Nuclear Information System (INIS)

Nazarenko, B.S.; Emets, V.G.

1998-01-01

An analysis of the prevailing laws and standards and technical documents (STD) to ensure safe operation of nuclear power installations, with requirements of nuclear, radiation and fire safety taken into account, has been performed. Proposals on application of some items of prevailing STD under conditions of the 'Ukrytie' operation are presented. Also given are technical proposals on correction of the prevailing operational standard documents and elaboration of special STD

Ultrastructural analysis of different human mesenchymal stem cells after in vitro expansion: a technical review

Directory of Open Access Journals (Sweden)

M. Miko

2015-10-01

Full Text Available Transmission electron microscopy reveals ultrastructural details of cells, and it is a valuable method for studying cell organelles. That is why we used this method for detailed morphological description of different adult tissuederived stem cells, focusing on the morphological signs of their functions (proteosynthetic activity, exchange with external environment, etc. and their comparison. Preparing a specimen from the cell culture suitable for transmission electron microscopy is, however, much more challenging than routine tissue processing for normal histological examination. There are several issues that need to be solved while working with cell pellets instead of solid tissue. Here we describe a simple protocol for the isolation and culture of mesenchymal stem cells from different adult tissues, with applications to stem cell biology and regenerative medicine. Since we are working with population of cells that was obtained after many days of passaging, very efficient and gentle procedures are highly necessary. We demonstrated that our semi-conservative approach regarding to histological techniques and processing of cells for transmission electron microscopy is a well reproducible procedure which results in quality pictures and images of cell populations with minimum distortions and artifacts. We also commented about riskiest steps and histochemical issues (e.g., precise pH, temperature while preparing the specimen. We bring full and detailed procedures of fixation, post-fixation, infiltration, embedding, polymerization and contrasting of cell obtained from in vitro cell and tissue cultures, with modifications according to our experience. All this steps are essential for us to know more about adult stem cells derived from different sources or about other random cell populations. The knowledge about detailed ultra-structure of adult stem cells cultured in vitro are also essential for their using in regenerative medicine and tissue engineering.

Ultrastructural Analysis of Different Human Mesenchymal Stem Cells After in Vitro Expansion: A Technical Review

Science.gov (United States)

Danišovič, Ľ.; Majidi, A.; Varga, I.

2015-01-01

Transmission electron microscopy reveals ultrastructural details of cells, and it is a valuable method for studying cell organelles. That is why we used this method for detailed morphological description of different adult tissue-derived stem cells, focusing on the morphological signs of their functions (proteosynthetic activity, exchange with external environment, etc.) and their comparison. Preparing a specimen from the cell culture suitable for transmission electron microscopy is, however, much more challenging than routine tissue processing for normal histological examination. There are several issues that need to be solved while working with cell pellets instead of solid tissue. Here we describe a simple protocol for the isolation and culture of mesenchymal stem cells from different adult tissues, with applications to stem cell biology and regenerative medicine. Since we are working with population of cells that was obtained after many days of passaging, very efficient and gentle procedures are highly necessary. We demonstrated that our semi-conservative approach regarding to histological techniques and processing of cells for transmission electron microscopy is a well reproducible procedure which results in quality pictures and images of cell populations with minimum distortions and artifacts. We also commented about riskiest steps and histochemical issues (e.g., precise pH, temperature) while preparing the specimen. We bring full and detailed procedures of fixation, post-fixation, infiltration, embedding, polymerization and contrasting of cell obtained from in vitro cell and tissue cultures, with modifications according to our experience. All this steps are essential for us to know more about adult stem cells derived from different sources or about other random cell populations. The knowledge about detailed ultra-structure of adult stem cells cultured in vitro are also essential for their using in regenerative medicine and tissue engineering. PMID:26708176

Why and How to Advance Technical Copywriting.

Science.gov (United States)

Henson, Leigh

1996-01-01

States that promotional writing for industrial/high-tech products, or technical copywriting, is gaining more attention in technical communication, although it is neglected in higher education. Testifies to the significance of technical copywriting. Suggests that dialogical audience analysis and an emphasis on rational appeal will contribute to…

Technical Analysis of Combined Solar Water Heating Systems for Cold Climate Regions

OpenAIRE

Hossein Lotfizadeh; André McDonald; Amit Kumar

2016-01-01

Renewable energy resources, which can supplement space and water heating for residential buildings, can have a noticeable impact on natural gas consumption and air pollution. This study considers a technical analysis of a combined solar water heating system with evacuated tube solar collectors for different solar coverage, ranging from 20% to 100% of the total roof area of a typical residential building located in Edmonton, Alberta, Canada. The alternative heating systems were conventional (n...

Technical Analysis of the Hydrogen Energy Station Concept, Phase I and Phase II

Energy Technology Data Exchange (ETDEWEB)

TIAX, LLC

2005-05-04

patterns would be most viable for an energy station, TIAX developed several criteria for selecting a representative set of technology configurations. TIAX applied these criteria to all possible technology configurations to determine an optimized set for further analysis, as shown in Table ES-1. This analysis also considered potential energy station operational scenarios and their impact upon hydrogen and power production. For example, an energy station with a 50-kWe reformer could generate enough hydrogen to serve up to 12 vehicles/day (at 5 kg/fill) or generate up to 1,200 kWh/day, as shown in Figure ES-1. Buildings that would be well suited for an energy station would utilize both the thermal and electrical output of the station. Optimizing the generation and utilization of thermal energy, hydrogen, and electricity requires a detailed look at the energy transfer within the energy station and the transfer between the station and nearby facilities. TIAX selected the Baseline configuration given in Table ES-1 for an initial analysis of the energy and mass transfer expected from an operating energy station. Phase II The purpose of this technical analysis was to analyze the development of a hydrogen-dispensing infrastructure for transportation applications through the installation of a 50-75 kW stationary fuel cell-based energy station at federal building sites. The various scenarios, costs, designs and impacts of such a station were quantified for a hypothetical cost-shared program that utilizes a natural gas reformer to provide hydrogen fuel for both the stack(s) and a limited number of fuel cell powered vehicles, with the possibility of using cogeneration to support the building heat load.

Technical characteristic analysis of wind energy conversion systems for sustainable development

International Nuclear Information System (INIS)

BoroumandJazi, G.; Rismanchi, B.; Saidur, R.

2013-01-01

Highlights: ► Identifying the required technical characteristics of sustainable wind power system. ► Observing Weibull probability function and artificial neural networks for reliability. ► Daily/monthly generation data are used to investigate the system’s availability. - Abstract: Wind energy as a clean, environmentally friendly and cost effective renewable energy resource, is taken into consideration by many developed and developing countries as a promising means to provide electrical energy. In feasibility study stage of the wind energy systems, the sustainability analysis is one of the main issues that can assure the investors and stockholders to invest in this renewable energy. Since a system can be truly sustainable by achieving the energetic, ecological and economic sustainability, the present study will focus on the technical characteristics and performance analysis of the wind energy systems. The relations between reliability, availability, energy and exergy efficiency, risk management and the environmental impact of the wind energy systems are investigated in the context of this study. It is concluded that the wind characteristics data and the wind speed are the main effective parameters on its reliability and availability. It is also revealed that considering the system loss, exergy efficiency results of the wind energy systems are more reliable than the energy efficiencies. Due to avoid future failure of the systems, the causes of the failure are investigated and it was concluded that the structural failures caused by storms and strong winds are known as the most prevalent failures

Savremene metode analize ulja u tehničkim sistemima / Modern methods of oil analysis in technical systems

Directory of Open Access Journals (Sweden)

Sreten R. Perić

2010-01-01

Full Text Available Analiza ulja na osnovu pravilno definisanog programa predstavlja veoma efikasan metod monitoringa stanja tehničkih sistema koji obezbeđuje rane upozoravajuće znake potencijalnih problema, koji vode ka otkazu i zastoju tehničkih sistema. Ova analiza je veoma efikasan alat programa za monitoring stanja tehničkih sistema. Mnogobrojni uređaji i testovi za analizu ulja omogućavaju kvalitetan monitoring i dijagnosticiranje problema koji nastaju u procesu podmazivanja. Korišćenjem programa za analizu motornih ulja: skraćuje se neplanirano vreme otkaza vozila, poboljšava pouzdanost vozila, produžava radni vek motora, optimizira interval zamene ulja i smanjuju troškovi održavanja vozila. / Different technical systems require an appropriate lubricant to be used at an appropriate place, at appropriate time and in appropriate quantity. Determination of technical systems condition has a very important role in the development of theory and practice of friction, wear and lubrication. Lubricant is, as a contact element of tribomechanical systems, a carrier of information about the state of the whole system, from the aspect of tribological and other ageing processes. The analysis of oils, based on a properly defined program, thus represents a very effective method for monitoring the condition of technical systems, which ensures early warning signals of potential problems that could lead to failure and break down of technical systems. Introduction It is not always simple to determine a type of lubricant, frequency of lubrication and the quantity of lubricant to be used. The optimal recommendation would be to follow specifications of technical system manufacturers, experience, lab research or professional recommendation of lubricant suppliers. Rational lubricant consumption can be obtained by timely oil replacement, which then enables a maximum possible period of use as well as high-quality lubrication. Since the primary role of lubricants is to

Technical and economic analysis of grid-connected PV/Wind energy stations in the Republic of Serbia under varying climatic conditions

OpenAIRE

Bakić, Vukman V.; Pezo, Milada L.; Stojković, Saša M.

2016-01-01

In this paper technical and economic analysis of grid-connected PV/Wind energy systems located in the Republic of Serbia are presented. The technical and economic data, of the various grid-connected PV/Wind hybrid energy systems for three different locations: Novi Sad, Belgrade and Kopaonik, using the transient simulations software TRNSYS and HOMER were obtained. The results obtained in this paper show that locations and technical characteristics of the energy systems have an important influe...

Keys of Japanese Prosody and Didactical-Technical Analysis of OJAD (Online Japanese Accent Dictionary)

Science.gov (United States)

Delgado Algarra, Emilio José

2016-01-01

Most of the studies focus on the teaching of foreign languages indicate that little attention is paid to the prosodic features both didactic materials and teaching-learning processes (Martinsen, Avord and Tanner, 2014). In this context and throughout this article, an analysis of the didactical and technical dimensions of OJAD (Japanese Accent…

Technical mechanics in constructional reactor safety

International Nuclear Information System (INIS)

Matthees, W.

1979-01-01

Reactor safety is based on close cooperation between a number of technical and scientific disciplines; most problems of reactor technology can be solved with the aid of technical mechanics. At the 5th International Conference on Structural Mechanics in Reactor Technology (5th SMIRT), one of the biggest conferences in the field of applied technical mechanics, about 800 papers were read giving the latest state of knowledge in the field of constructional reactor safety. The main subject of the conference was the analysis of material behaviour under high loads; the information and methods of these analysis go far beyond what is required in the conventional field. (orig./UA) [de

A Preliminary Rhetoric of Technical Copywriting.

Science.gov (United States)

Henson, Leigh

1994-01-01

Discusses the rhetorical elements of technical copywriting, including its shared communicative aims with technical writing; authorship considerations such as ethics, education, and professionalism; and the concerns of promotional strategy, audience analysis, choice of media and materials, writing strategy, and style. (SR)

Formation of trading strategy based on technical analysis and application in the FOREX market

OpenAIRE

Butkus, Mindaugas; Tamašauskas, Mantas

2016-01-01

This paper accomplishes modification of technical analysis based trading strategy for the FOREX market. New strategy performance was checked using historical data. Most profitable modification was excluded and optimized. Straipsnyje atliktas technine analize grįstos prekybos strategijos, skirtos FOREX rinkai, modifikavimas. Naujos strategijos veikimas patikrintas su istoriniais duomenimis. Buvo atrinkta ir optimizuota pelningiausia modifikacija.

Final Technical Report: Hydrogen Codes and Standards Outreach

Energy Technology Data Exchange (ETDEWEB)

Hall, Karen I.

2007-05-12

This project contributed significantly to the development of new codes and standards, both domestically and internationally. The NHA collaborated with codes and standards development organizations to identify technical areas of expertise that would be required to produce the codes and standards that industry and DOE felt were required to facilitate commercialization of hydrogen and fuel cell technologies and infrastructure. NHA staff participated directly in technical committees and working groups where issues could be discussed with the appropriate industry groups. In other cases, the NHA recommended specific industry experts to serve on technical committees and working groups where the need for this specific industry expertise would be on-going, and where this approach was likely to contribute to timely completion of the effort. The project also facilitated dialog between codes and standards development organizations, hydrogen and fuel cell experts, the government and national labs, researchers, code officials, industry associations, as well as the public regarding the timeframes for needed codes and standards, industry consensus on technical issues, procedures for implementing changes, and general principles of hydrogen safety. The project facilitated hands-on learning, as participants in several NHA workshops and technical meetings were able to experience hydrogen vehicles, witness hydrogen refueling demonstrations, see metal hydride storage cartridges in operation, and view other hydrogen energy products.

The back end of the nuclear fuel cycle: technical and economic analysis-Part 1

International Nuclear Information System (INIS)

Roglans-Ribas, J.; Spinrad, B.I.

1990-01-01

The back end of the nuclear fuel cycle has been analyzed under current conditions in the United States, taking into consideration the framework defined by the Nuclear Waste Policy Act of 1982 and its amendments. The different steps of the back end of the fuel cycle are studied and different alternatives are compared under technical and economic criteria. Several technical issues have been analyzed for their impact on the economics of the fuel cycle. The bases for the analysis are explained, and the results for a once-through cycle are presented. The results show that a repository in tuff represents the minimum cost situation. The economic model appears very sensitive to several parameters, in particular the period of retrievability and the storage costs

Iranian nurses' experience of essential technical competences in disaster response: A qualitative content analysis study.

Science.gov (United States)

Aliakbari, Fatemeh; Bahrami, Masoud; Aein, Fereshteh; Khankeh, Hamidreza

2014-11-01

Today disasters are a part of many people's lives. Iran has a long history of disaster events and nurses are one of the most significant groups within the Iranian disaster relief operations, providing immediate and long-term care for those affected by the disaster. However, the technical competence of Iranian nurses and their training for this work has received little attention. This article presents the results of a study that aims to explore this context. A qualitative study was conducted using in-depth interviews to collect data from 30 nurses, who were deliberately selected from the health centers affiliated to the Isfahan University of Medical Sciences. Themes were identified using the conventional qualitative content analysis. The trustworthiness of the study was supported by considering the auditability, neutrality, consistency, and transferability. The study lasted from 2011 to 2012. Data analysis undertaken for the qualitative study resulted in the identification of five main themes, which included: (1) Management competences, (2) ethical and legal competences, (3) team working, and (4) personal abilities and the specific technical competences presented in this report. This report presents an overview of the nursing technical capabilities required for Iranian nurses during disaster relief. It is argued that additional competencies are required for nurses who care in high-risk situations, including disasters. Nurses need to prepare themselves more effectively to be responsible and effective in nursing care.

Technical and clinical performance of a new assay to detect squamous cell carcinoma antigen levels for the differential diagnosis of cervical, lung, and head and neck cancer.

Science.gov (United States)

Holdenrieder, Stefan; Molina, Rafael; Qiu, Ling; Zhi, Xiuyi; Rutz, Sandra; Engel, Christine; Kasper-Sauer, Pia; Dayyani, Farshid; Korse, Catharina M

2018-04-01

In squamous cell carcinoma, squamous cell carcinoma antigen levels are often elevated. This multi-center study evaluated the technical performance of a new Elecsys ® squamous cell carcinoma assay, which measures serum squamous cell carcinoma antigen 1 and 2 levels in an equimolar manner, and investigated the potential of squamous cell carcinoma antigen for differential diagnosis of cervical, lung, and head and neck squamous cell carcinoma.Assay precision and method comparison experiments were performed across three European sites. Reference ranges for reportedly healthy individuals were determined using samples from banked European and Chinese populations. Differential diagnosis experiments determined whether cervical, lung, or head and neck cancer could be differentiated from apparently healthy, benign, or other malignant cohorts using squamous cell carcinoma antigen levels alone. Squamous cell carcinoma antigen cut-off levels were calculated based on squamous cell carcinoma antigen levels at 95% specificity. Repeatability coefficients of variation across nine analyte concentrations were ≤5.3%, and intermediate precision coefficients of variation were ≤10.3%. Method comparisons showed good correlations with Architect and Kryptor systems (slopes of 1.1 and 1.5, respectively). Reference ranges for 95th percentiles for apparently healthy individuals were 2.3 ng/mL (95% confidence interval: 1.9-3.8; European cohort, n = 153) and 2.7 ng/mL (95% confidence interval: 2.2-3.3; Chinese cohort, n = 146). Strongest differential diagnosis results were observed for cervical squamous cell carcinoma: receiver operating characteristic analysis showed that squamous cell carcinoma antigen levels (2.9 ng/mL cut-off) differentiate cervical squamous cell carcinoma (n = 127) from apparently healthy females (n = 286; area under the curve: 86.2%; 95% confidence interval: 81.8-90.6; sensitivity: 61.4%; specificity: 95.6%), benign diseases (n = 187; area

Technical and economical analysis of an induced demand in the photovoltaic sector

International Nuclear Information System (INIS)

Ciorba, Umberto; Pauli, Francesco; Menna, Pietro

2004-01-01

We analyse the potential economic impact of a demand of photovoltaic (PV) devices in Morocco, in terms of induced production and job creation. In Morocco a high potential for PV installations exists as proved by the number of national and international deployment initiatives currently underway. In our study, we first describe the manufacturing process providing as final output the solar modules and associate the corresponding costs to each step of the process. These costs are needed to determine the technical coefficients of an ad hoc PV sector to be added to the Morocco Leontief matrix. Then, using the input-output methodology, we evaluate the economic impact of the production of 5 MW p modules a year under different hypotheses. A production of 5 MW p PV modules, which require an overall investment of euro 16.3 millions, increases production of euro 57.6 millions if cells are locally produced and of euro 22.3 millions when the cells are imported, creating 2570 and 489 jobs, respectively. These results outline the importance of availability of intermediate inputs in local economical context

Parallel single-cell analysis microfluidic platform

NARCIS (Netherlands)

van den Brink, Floris Teunis Gerardus; Gool, Elmar; Frimat, Jean-Philippe; Bomer, Johan G.; van den Berg, Albert; le Gac, Severine

2011-01-01

We report a PDMS microfluidic platform for parallel single-cell analysis (PaSCAl) as a powerful tool to decipher the heterogeneity found in cell populations. Cells are trapped individually in dedicated pockets, and thereafter, a number of invasive or non-invasive analysis schemes are performed.

Canadian CANDU plant data systems for technical surveillance and analysis

International Nuclear Information System (INIS)

Deverno, M.; Pothier, H.; Xian, C.; Grosbois, J. De; Bosnich, M.

1996-01-01

Plant data systems are emerging as a critical plant support system technology. In particular, plant-wide Historical Data Systems (HDS) are pivotal to the successful implementation of technical surveillance and analysis programs supporting plant operations, maintenance, safety, and licensing activities. In partnership with Canadian CANDU utility and design organizations, AECL has conducted a review of current Canadian CANDU HDS approaches with emphasis on understanding the existing functionality and uses of plant historical data systems, their future needs and benefits. The results is a vision of a plant-wide HDS providing seamless access to both near real-time and historical data, user tool-kits for data visualization and analysis, and data management of the large volume of data acquired during the life of a plant. The successful implementation of the HDS vision will lead to higher capability and capacity factors while minimizing Operations, Maintenance, and Administration (OM and A) costs. (author). 5 refs, 3 figs

Canadian CANDU plant data systems for technical surveillance and analysis

Energy Technology Data Exchange (ETDEWEB)

Deverno, M; Pothier, H; Xian, C [Atomic Energy of Canada Ltd., Control Centre Technology Branch, Fredericton, NB (Canada); Grosbois, J De; Bosnich, M [Atomic Energy of Canada Ltd., Control Centre Technology Branch, Chalk River, ON (Canada). Chalk River Labs.

1997-12-31

Plant data systems are emerging as a critical plant support system technology. In particular, plant-wide Historical Data Systems (HDS) are pivotal to the successful implementation of technical surveillance and analysis programs supporting plant operations, maintenance, safety, and licensing activities. In partnership with Canadian CANDU utility and design organizations, AECL has conducted a review of current Canadian CANDU HDS approaches with emphasis on understanding the existing functionality and uses of plant historical data systems, their future needs and benefits. The results is a vision of a plant-wide HDS providing seamless access to both near real-time and historical data, user tool-kits for data visualization and analysis, and data management of the large volume of data acquired during the life of a plant. The successful implementation of the HDS vision will lead to higher capability and capacity factors while minimizing Operations, Maintenance, and Administration (OM and A) costs. (author). 5 refs, 3 figs.

An Application of Fuzzy Theory to Technical Competency Analysis for the Entry-Level Electronic Technician.

Science.gov (United States)

Chang, Liang-Te; And Others

A study was conducted to develop the electronic technical competencies of duty and task analysis by using a revised DACUM (Developing a Curriculum) method, a questionnaire survey, and a fuzzy synthesis operation. The revised DACUM process relied on inviting electronics trade professionals to analyze electronic technology for entry-level…

Modern Methods of Multidimensional Data Visualization: Analysis, Classification, Implementation, and Applications in Technical Systems

Directory of Open Access Journals (Sweden)

I. K. Romanova

2016-01-01

Full Text Available The article deals with theoretical and practical aspects of solving the problem of visualization of multidimensional data as an effective means of multivariate analysis of systems. Several classifications are proposed for visualization techniques, according to data types, visualization objects, the method of transformation of coordinates and data. To represent classification are used charts with links to the relevant work. The article also proposes two classifications of modern trends in display technology, including integration of visualization techniques as one of the modern trends of development, along with the introduction of interactive technologies and the dynamics of development processes. It describes some approaches to the visualization problem, which are concerned with fulfilling the needs. The needs are generated by the relevant tasks such as information retrieval in global networks, development of bioinformatics, study and control of business processes, development of regions, etc. The article highlights modern visualization tools, which are capable of improving the efficiency of the multivariate analysis and searching for solutions in multi-objective optimization of technical systems, but are not very actively used for such studies. These are horizontal graphs, graphics "quantile-quantile", etc. The paper proposes to use Choropleth cards traditionally used in cartography for simultaneous presentation of the distribution parameters of several criteria in the space. It notes that visualizations of graphs in network applications can be more actively used to describe the control system. The article suggests using the heat maps to provide graphical representation of the sensitivity of the system quality criteria under variations of options (multivariate analysis of technical systems. It also mentions that it is useful to extend the supervising heat maps to the task of estimating quality of identify in constructing system models. A

Analysis of cogeneration system using fuel cell: cases study; Analise de sistema de cogeracao utilizando celula de combustivel: estudo de casos

Energy Technology Data Exchange (ETDEWEB)

Silveira, Jose Luz; Leal, Elisangela Martins [UNESP, Guaratingueta, SP (Brazil). Escola de Engenharia. Dept. de Energia]. E-mails: joseluz@feg.unesp.br; elisange@feg.unesp.br

2000-07-01

In this paper, a methodology for the study of a molten carbonate fuel cell cogeneration system associated to an absorption refrigeration system, for the electricity and cold water production, and applied to two establishments, is presented. This system permits the recovery of waste heat, available between 600 deg C e 700 deg C. Initially, some technical information about the most diffusing types of the fuel cell demonstration in the world are presented. In the next step, an energetic, exergetic and economic analysis are carry out, seeking the use of fuel cells, in conditions of prices and interest of Brazil. In conclusion, the fuel cell cogeneration system may have an excellent opportunity to strengthen the decentralized energy production in the Brazilian energy scene. (author)

Danglers in Patient Information Leaflets and Technical Manuals

DEFF Research Database (Denmark)

Køhler Simonsen, Henrik

2014-01-01

in fact been proved. The analysis and the discussion showed that dangling participles are not very frequent in PILs, but much more common in technical manuals. The data showed that there were no “ludicrous” danglers,(see Matthews and Matthews 2008:146), in PILcorp. However, the analysis showed that both......Dangling participles and other types of ambiguous or unclear sentence constructions in directive and informative medical and technical texts, such as patient information leaflets (PILs) and technical manuals, render instructions unclear and potentially dangerous for the layman reader, i......, and readability on the basis of two corpora: a corpus of PILs (PILcorp) and a corpus of technical manuals (TECHcorp). The hypothesis is that patient information leaflets will contain fewer dangling constructions than technical manuals because of the strict regulations on product information texts including PILs...

Proton exchange membrane fuel cells for electrical power generation on-board commercial airplanes.

Energy Technology Data Exchange (ETDEWEB)

Curgus, Dita Brigitte; Munoz-Ramos, Karina (Sandia National Laboratories, Albuquerque, NM); Pratt, Joseph William; Akhil, Abbas Ali (Sandia National Laboratories, Albuquerque, NM); Klebanoff, Leonard E.; Schenkman, Benjamin L. (Sandia National Laboratories, Albuquerque, NM)

2011-05-01

Deployed on a commercial airplane, proton exchange membrane fuel cells may offer emissions reductions, thermal efficiency gains, and enable locating the power near the point of use. This work seeks to understand whether on-board fuel cell systems are technically feasible, and, if so, if they offer a performance advantage for the airplane as a whole. Through hardware analysis and thermodynamic and electrical simulation, we found that while adding a fuel cell system using today's technology for the PEM fuel cell and hydrogen storage is technically feasible, it will not likely give the airplane a performance benefit. However, when we re-did the analysis using DOE-target technology for the PEM fuel cell and hydrogen storage, we found that the fuel cell system would provide a performance benefit to the airplane (i.e., it can save the airplane some fuel), depending on the way it is configured.

Proton Exchange Membrane Fuel Cells for Electrical Power Generation On-Board Commercial Airplanes

Energy Technology Data Exchange (ETDEWEB)

Pratt, Joesph W. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Klebanoff, Leonard E. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Munoz-Ramos, Karina [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Akhil, Abbas A. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Curgus, Dita B. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Schenkman, Benjamin L. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

2011-05-01

Deployed on a commercial airplane, proton exchange membrane fuel cells may offer emissions reductions, thermal efficiency gains, and enable locating the power near the point of use. This work seeks to understand whether on-board fuel cell systems are technically feasible, and, if so, if they offer a performance advantage for the airplane as a whole. Through hardware analysis and thermodynamic and electrical simulation, we found that while adding a fuel cell system using today’s technology for the PEM fuel cell and hydrogen storage is technically feasible, it will not likely give the airplane a performance benefit. However, when we re-did the analysis using DOE-target technology for the PEM fuel cell and hydrogen storage, we found that the fuel cell system would provide a performance benefit to the airplane (i.e., it can save the airplane some fuel), depending on the way it is configured.

Technical efficiency of Shiraz school of medicine in research and education domains: a data envelopment analysis.

Science.gov (United States)

Delavari, Somayeh; Rezaee, Rita; Hatam, Nahid; Delavari, Sajad

2016-01-01

Efficiency evaluation of universities and faculties is one of the tools that help managers to identify the departments' strengths and weakness. The main objective of the present research was to measure and compare the technical efficiency of Shiraz school of medicine departments using Data Envelopment Analysis (DEA) technique. This cross-sectional and retrospective study was performed on clinical and non-clinical departments in research and education domains over the period of 2006 to 2011. Different inputs and outputs were considered for research and educational domain separately. Efficiency was measured based on the observed optimal performance. Findings showed that pathology and anatomy departments achieved the score of 100 in technical efficiency in education during 2006 to 2011. During this period, parasitology, psychiatric and pediatrics department's achieved the score of 100 for technical efficiency in research domain. The lowest mean of relative educational efficiency belonged to orthopedic department; as to relative research efficiency, the lowest mean was shown in orthopedics and genetics departments. The mean technical efficiency of non-medical departments in education and research domain was 91.93 and 76.08, respectively, while the mean technical efficiency of the clinical department in educational and research fields was 91.02 and 82.23, respectively. Using multiple input and output in DEA technique provided a comprehensive evaluation of efficiency in Shiraz school of medicine departments. The DEA could successfully estimate the technical efficiency of the departments in research and educational fields. Moreover, the deficiency in each department was found; this could help them to plan for improvement.

Geospatial Analysis of Renewable Energy Technical Potential on Tribal Lands

Energy Technology Data Exchange (ETDEWEB)

Doris, E.; Lopez, A.; Beckley, D.

2013-02-01

This technical report uses an established geospatial methodology to estimate the technical potential for renewable energy on tribal lands for the purpose of allowing Tribes to prioritize the development of renewable energy resources either for community scale on-tribal land use or for revenue generating electricity sales.

Comparisons: Technical-Tactical and Time-Motion Analysis of Mixed Martial Arts by Outcomes.

Science.gov (United States)

Miarka, Bianca; Vecchio, Fabrício B D; Camey, Suzi; Amtmann, John A

2016-07-01

Miarka, B, Vecchio, FBD, Camey, S, and Amtmann, JA. Comparisons: technical-tactical and time-motion analysis of mixed martial arts by outcomes. J Strength Cond Res 30(7): 1975-1984, 2016-The aim of this study was to compare time-motion and technical-tactical analysis between paired outcomes and rounds of mixed martial arts (MMA) matches. The sample consisted of 645 rounds of MMA competition paired by outcomes (first round, winners n = 215 and losers n = 215; second round, winners n = 215 and losers n = 215; third round, winners n = 215 and losers n = 215). The time-motion variables were categorized into low-intensity or high-intensity, stand-up or groundwork situations. Stand-up techniques were analyzed by observing total strikes to the head and body, and takedowns. The actions on the ground were analyzed by observing submission activity, including successful choking and joint locking actions, and also positional improvements, including advances to the mount, half guard, and side and back positions. Chi-squared and Wilcoxon tests were conducted with a significance level of p ≤ 0.05. Results showed that winners had higher values for total strikes and submissions in all rounds, and also positional improvements, over losers. The standing combat with low-intensity comparisons presented differences between the rounds first, with a median of 2:33.5 (P25-P75%: 1:20-3:56) minute, second, with 2:37 (1:24-3:59) minute, and third, with 2:07 (1:06-3:39.2) minute. These data suggest a focus on the intermittent demand presented in combat phases with a special attention to the strike and ground technical-tactical skills; strength and conditioning coaches could emphasize the effort pause ratios for both standing and ground combat that mimic the requirements of MMA, especially during the third round.

45 CFR 1158.205 - Professional and technical services.

Science.gov (United States)

2010-10-01

... advice and analysis directly applying any professional or technical discipline. For example, drafting of... 45 Public Welfare 3 2010-10-01 2010-10-01 false Professional and technical services. 1158.205... Own Employees § 1158.205 Professional and technical services. (a) The prohibition on the use of...

7 CFR 3018.205 - Professional and technical services.

Science.gov (United States)

2010-01-01

... and analysis directly applying any professional or technical discipline. For example, drafting of a... 7 Agriculture 15 2010-01-01 2010-01-01 false Professional and technical services. 3018.205 Section....205 Professional and technical services. (a) The prohibition on the use of appropriated funds, in...

7 CFR 3018.300 - Professional and technical services.

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2010-01-01

... and analysis directly applying any professional or technical discipline. For example, drafting or a... 7 Agriculture 15 2010-01-01 2010-01-01 false Professional and technical services. 3018.300 Section... Employees § 3018.300 Professional and technical services. (a) The prohibition on the use of appropriated...

49 CFR 20.300 - Professional and technical services.

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2010-10-01

... and analysis directly applying any professional or technical discipline. For example, drafting or a... 49 Transportation 1 2010-10-01 2010-10-01 false Professional and technical services. 20.300... Activities by Other Than Own Employees § 20.300 Professional and technical services. (a) The prohibition on...

20 CFR 438.205 - Professional and technical services.

Science.gov (United States)

2010-04-01

... advice and analysis directly applying any professional or technical discipline. For example, drafting of... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Professional and technical services. 438.205... Own Employees § 438.205 Professional and technical services. (a) The prohibition on the use of...

International comparisons of the technical efficiency of the hospital sector: panel data analysis of OECD countries using parametric and non-parametric approaches.

Science.gov (United States)

Varabyova, Yauheniya; Schreyögg, Jonas

2013-09-01

There is a growing interest in the cross-country comparisons of the performance of national health care systems. The present work provides a comparison of the technical efficiency of the hospital sector using unbalanced panel data from OECD countries over the period 2000-2009. The estimation of the technical efficiency of the hospital sector is performed using nonparametric data envelopment analysis (DEA) and parametric stochastic frontier analysis (SFA). Internal and external validity of findings is assessed by estimating the Spearman rank correlations between the results obtained in different model specifications. The panel-data analyses using two-step DEA and one-stage SFA show that countries, which have higher health care expenditure per capita, tend to have a more technically efficient hospital sector. Whether the expenditure is financed through private or public sources is not related to the technical efficiency of the hospital sector. On the other hand, the hospital sector in countries with higher income inequality and longer average hospital length of stay is less technically efficient. Copyright © 2013 The Authors. Published by Elsevier Ireland Ltd.. All rights reserved.

Technical specification improvement through safety margin considerations

International Nuclear Information System (INIS)

Howard, R.C.; Jansen, R.L.

1986-01-01

Westinghouse has developed an approach for utilizing safety analysis margin considerations to improve plant operability through technical specification revision. This approach relies on the identification and use of parameter interrelations and sensitivities to identify acceptable operating envelopes. This paper summarizes technical specification activities to date and presents the use of safety margin considerations as another viable method to obtain technical specification improvement

Development of international standards for surface analysis by ISO technical committee 201 on surface chemical analysis

International Nuclear Information System (INIS)

Powell, C.J.

1999-01-01

Full text: The International Organization for Standardization (ISO) established Technical Committee 201 on Surface Chemical Analysis in 1991 to develop documentary standards for surface analysis. ISO/TC 201 met first in 1992 and has met annually since. This committee now has eight subcommittees (Terminology, General Procedures, Data Management and Treatment, Depth Profiling, AES, SIMS, XPS, and Glow Discharge Spectroscopy (GDS)) and one working group (Total X-Ray Fluorescence Spectroscopy). Each subcommittee has one or more working groups to develop standards on particular topics. Australia has observer-member status on ISO/TC 201 and on all ISO/TC 201 subcommittees except GDS where it has participator-member status. I will outline the organization of ISO/TC 201 and summarize the standards that have been or are being developed. Copyright (1999) Australian X-ray Analytical Association Inc

Non-invasive quality evaluation of confluent cells by image-based orientation heterogeneity analysis.

Science.gov (United States)

Sasaki, Kei; Sasaki, Hiroto; Takahashi, Atsuki; Kang, Siu; Yuasa, Tetsuya; Kato, Ryuji

2016-02-01

In recent years, cell and tissue therapy in regenerative medicine have advanced rapidly towards commercialization. However, conventional invasive cell quality assessment is incompatible with direct evaluation of the cells produced for such therapies, especially in the case of regenerative medicine products. Our group has demonstrated the potential of quantitative assessment of cell quality, using information obtained from cell images, for non-invasive real-time evaluation of regenerative medicine products. However, image of cells in the confluent state are often difficult to evaluate, because accurate recognition of cells is technically difficult and the morphological features of confluent cells are non-characteristic. To overcome these challenges, we developed a new image-processing algorithm, heterogeneity of orientation (H-Orient) processing, to describe the heterogeneous density of cells in the confluent state. In this algorithm, we introduced a Hessian calculation that converts pixel intensity data to orientation data and a statistical profiling calculation that evaluates the heterogeneity of orientations within an image, generating novel parameters that yield a quantitative profile of an image. Using such parameters, we tested the algorithm's performance in discriminating different qualities of cellular images with three types of clinically important cell quality check (QC) models: remaining lifespan check (QC1), manipulation error check (QC2), and differentiation potential check (QC3). Our results show that our orientation analysis algorithm could predict with high accuracy the outcomes of all types of cellular quality checks (>84% average accuracy with cross-validation). Copyright © 2015 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

45 CFR 1158.300 - Professional and technical services.

Science.gov (United States)

2010-10-01

... analysis directly applying any professional or technical discipline. For example, drafting or a legal... 45 Public Welfare 3 2010-10-01 2010-10-01 false Professional and technical services. 1158.300... Other Than Own Employees § 1158.300 Professional and technical services. (a) The prohibition on the use...

10 CFR 601.300 - Professional and technical services.

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2010-01-01

... and analysis directly applying any professional or technical discipline. For example, drafting or a... 10 Energy 4 2010-01-01 2010-01-01 false Professional and technical services. 601.300 Section 601... Activities by Other Than Own Employees § 601.300 Professional and technical services. (a) The prohibition on...

22 CFR 311.205 - Professional and technical services.

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2010-04-01

... and analysis directly applying any professional or technical discipline. For example, drafting of a... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Professional and technical services. 311.205... § 311.205 Professional and technical services. (a) The prohibition on the use of appropriated funds, in...

45 CFR 1168.300 - Professional and technical services.

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2010-10-01

... and analysis directly applying any professional or technical discipline. For example, drafting or a... 45 Public Welfare 3 2010-10-01 2010-10-01 false Professional and technical services. 1168.300... Activities by Other Than Own Employees § 1168.300 Professional and technical services. (a) The prohibition on...

22 CFR 138.300 - Professional and technical services.

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2010-04-01

... and analysis directly applying any professional or technical discipline. For example, drafting or a... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Professional and technical services. 138.300... Activities by Other Than Own Employees § 138.300 Professional and technical services. (a) The prohibition on...

22 CFR 519.300 - Professional and technical services.

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2010-04-01

... and analysis directly applying any professional or technical discipline. For example, drafting or a... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Professional and technical services. 519.300... by Other Than Own Employees § 519.300 Professional and technical services. (a) The prohibition on the...

22 CFR 227.300 - Professional and technical services.

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2010-04-01

... and analysis directly applying any professional or technical discipline. For example, drafting or a... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Professional and technical services. 227.300... Activities by Other Than Own Employees § 227.300 Professional and technical services. (a) The prohibition on...

20 CFR 438.300 - Professional and technical services.

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2010-04-01

... analysis directly applying any professional or technical discipline. For example, drafting of a legal... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Professional and technical services. 438.300... Other Than Own Employees § 438.300 Professional and technical services. (a) The prohibition on the use...

34 CFR 82.300 - Professional and technical services.

Science.gov (United States)

2010-07-01

... and analysis directly applying any professional or technical discipline. For example, drafting or a... 34 Education 1 2010-07-01 2010-07-01 false Professional and technical services. 82.300 Section 82... by Other Than Own Employees § 82.300 Professional and technical services. (a) The prohibition on the...

Hot Cell Post-Irradiation Examination and Poolside Inspection of Nuclear Fuel. Proceedings of the IAEA-HOTLAB Technical Meeting

International Nuclear Information System (INIS)

2013-04-01

The growing operational requirements for nuclear fuel, such as longer fuel cycles, higher burnups and wider use of transient regimes, require more robust fuel designs and more radiation resistant materials. Development of such advanced fuels is only possible with testing and analysis of their performance and application of adequate post-irradiation examination (PIE) methods and techniques. In addition, operational feedback data from poolside and PIE facilities are absolutely necessary for verification of fuel modelling codes and analysis of fuel failure mechanisms. For these reasons, the International Atomic Energy Agency (IAEA) has supported the international exchange of knowledge and sharing of best practices in the application of modern destructive and non-destructive methods of investigation of highly radioactive materials through a series of technical meetings (TMs), the last of which was held in 2006 in Buenos Aires. Since 1963, similar meetings, initially at the European level, have been organized by the Hot Laboratories and Remote Handling Working Group (HOTLAB), a partner in the development of the IAEA's Post Irradiation Examination Facilities Database (PIEDB), part of the IAEA's Integrated Nuclear Fuel Cycle Information System. With this successful partnership in mind, in 2010 the IAEA Technical Working Group on Fuel Performance and Technology recommended that a joint IAEA-HOTLAB TM be held on 'Hot Cell Post-Irradiation Examination and Pool-Side Inspection of Nuclear Fuel', covering questions relevant to the IAEA sub-programmes on 'Nuclear Power Reactor Fuel Engineering' and 'Management of Spent Fuel from Nuclear Power Reactors'. The TM was held on 23-27 May 2011, in Smolenice, Slovakia, with the participation of a large number of interested organizations and comprehensive coverage of major PIE and poolside inspection issues relating to both operation and storage of fuel for nuclear power reactors. The proceedings, summaries and conclusions of that joint

Plant cell wall polysaccharide analysis during cell elongation

DEFF Research Database (Denmark)

Guo, Xiaoyuan

Plant cell walls are complex structures whose composition and architecture are important to various cellular activities. Plant cell elongation requires a high level of rearrangement of the cell wall polymers to enable cell expansion. However, the cell wall polysaccharides dynamics during plant cell...... elongation is poorly understood. This PhD project aims to elucidate the cell wall compositional and structural change during cell elongation by using Comprehensive Microarray Polymer Profiling (CoMPP), microscopic techniques and molecular modifications of cell wall polysaccharide. Developing cotton fibre......, pea and Arabidopsis thaliana were selected as research models to investigate different types of cell elongation, developmental elongation and tropism elongation. A set of comprehensive analysis covering 4 cotton species and 11 time points suggests that non-cellulosic polysaccharides contribute...

Operating experience feedback report: Technical specifications: Commercial power reactors

International Nuclear Information System (INIS)

O'Reilly, P.D.; Plumlee, G.L. III.

1989-03-01

This report documents a trends and patterns analysis of technical specification (TS)-related licensee event reports (LERs) conducted by the Nuclear Regulatory Commission's (NRC's) Office for Analysis and Evaluation of Operational Data (AEOD). The objectives of this analysis were (1) to identify and catalog technical specification-related LERs, (2) to categorize and evaluate the events reported in these a LERs, (3) to identify any issues arising from the evaluation which appear to have generic safety significance, or which relate to the on-going Technical Specification Improvement Program, and (4) to trend the results obtained from the analysis of the data obtained in (1) through (3). 9 refs., 9 figs., 22 tabs

Program of scientific investigations and development of solid-oxide fuel cells (SOFC) in VNIITF. Proposals on scientific and technical collaboration and SOFC commercialization

Energy Technology Data Exchange (ETDEWEB)

Kleschev, Yu.N.; Chukharev, V.F.

1996-04-01

This paper describes proposals on scientific and technical collaborations pertaining to solid oxide fuel cell commercialization. Topics included for discussion are: materials research and manufacture; market estimation and cost; directions of collaboration; and project of proposals on joint enterprise creation.

Security analysis of socio-technical physical systems

NARCIS (Netherlands)

Lenzini, Gabriele; Mauw, Sjouke; Ouchani, Samir

2015-01-01

Recent initiatives that evaluate the security of physical systems with objects as assets and people as agents – here called socio-technical physical systems – have limitations: their agent behavior is too simple, they just estimate feasibility and not the likelihood of attacks, or they do estimate

Technical evaluation report of the Fort St. Vrain final draft upgraded technical specifications

International Nuclear Information System (INIS)

Kimura, C.Y.

1989-01-01

This report is a technical evaluation of the final draft of the Fort St. Vrain (FSV) Upgraded Technical Specifications (UT/S) as issued by Public Service of Colorado (PSC) on May 27, 1988 with subsequent supplemental updates issued on June 15, 1988 and August 5, 1988. It has been compared for consistency, and safety conservatism with the Fort St. Vrain (FSV) Updated Final Safety Analysis Report (FSAR), the FSV Safety Evaluation Report (SER), the Facility Operating License, DPR-34, and all amendments to the Facility Operating License issued as of June 1, 1988, and Appendix A to the Operating License DPR-34, Technical Specifications. Because of the age of the plant, no supplements to the Fort St. Vrain SER have been issued since the original SER was not issued as a WASH or a NUREG report. This made it necessary to review all amendments to the Facility Operating License since they would contain the safety evaluations done to support changes to the Facility Operating License. The upgraded Fort St. Vrain Technical Specifications were also broadly compared with the latest Westinghouse Standard Technical Specifications (WSTS) to assure that what was proposed for Fort St. Vrain was consistent with the latest NRC staff practices for standard technical specifications

ANALYSIS OF THE POSSIBILITY OF INTEGRATING A MINING RIGHT-ANGLE PLANETARY GEARBOX WITH TECHNICAL DIAGNOSTICS SYSTEMS

Directory of Open Access Journals (Sweden)

Andrzej WIECZOREK

2016-12-01

Full Text Available A key factor enabling the achievement of the required capacity by longwall mining systems is to obtain a satisfactory service life for individual components of such systems. Such components include right-angle planetary gearboxes for armoured face conveyors. An increase in the service life of such equipment can be achieved by ensuring adequacy in terms of design, materials and organization. As a part of organizational changes, the use of individual diagnostics systems may have the greatest impact on the service life of mining gearboxes; however, their widespread implementation is limited by economic and operational barriers. This paper presents an analysis of the possibility of integrating mining gearboxes with electronic systems of technical diagnostics, as well as expanding the scope of the technical condition monitoring by the machines operating together with these gearboxes. As a result of the calculation and design work performed, it has been demonstrated that it is possible to integrate technical diagnostics systems with advanced data transmission capabilities inside gearboxes.

Micromagnetic Cancer Cell Immobilization and Release for Real-Time Single Cell Analysis

Energy Technology Data Exchange (ETDEWEB)

Jaiswal, Devina; Rad, Armin Tahmasbi [Department of Biomedical Engineering, University of Connecticut, Storrs, CT, 06269 (United States); Nieh, Mu-Ping [Department of Biomedical Engineering, University of Connecticut, Storrs, CT, 06269 (United States); Department of Chemical and Biomolecular Engineering, University of Connecticut, Storrs, CT 06269 (United States); Polymer Program, Institute of Materials Science, University of Connecticut, Storrs, CT 06269 (United States); Claffey, Kevin P. [Department of Cell Biology, University of Connecticut Health Center, Farmington, CT 06030 (United States); Hoshino, Kazunori, E-mail: hoshino@engr.uconn.edu [Department of Biomedical Engineering, University of Connecticut, Storrs, CT, 06269 (United States)

2017-04-01

Understanding the interaction of live cells with macromolecules is crucial for designing efficient therapies. Considering the functional heterogeneity found in cancer cells, real-time single cell analysis is necessary to characterize responses. In this study, we have designed and fabricated a microfluidic channel with patterned micromagnets which can temporarily immobilize the cells during analysis and release them after measurements. The microchannel is composed of plain coverslip top and bottom panels to facilitate easy microscopic observation and undisturbed application of analytes to the cells. Cells labeled with functionalized magnetic beads were immobilized in the device with an efficiency of 90.8±3.6%. Since the micromagnets are made of soft magnetic material (Ni), they released cells when external magnetic field was turned off from the channel. This allows the reuse of the channel for a new sample. As a model drug analysis, the immobilized breast cancer cells (MCF7) were exposed to fluorescent lipid nanoparticles and association and dissociation were measured through fluorescence analysis. Two concentrations of nanoparticles, 0.06 µg/ml and 0.08 µg/ml were tested and time lapse images were recorded and analyzed. The microfluidic device was able to provide a microenvironment for sample analysis, making it an efficient platform for real-time analysis.

Degrees of systematic thoroughness: A text analysis of student technical science writing

Science.gov (United States)

Esch, Catherine Julia

This dissertation investigates student technical science writing and use of evidence. Student writers attended a writing-intensive undergraduate university oceanography course where they were required to write a technical paper drawing from an instructor-designed software program, Our Dynamic Planet. This software includes multiple interactive geological data sets relevant to plate tectonics. Through qualitative text analysis of students science writing, two research questions frame the study asking: How are the papers textually structured? Are there distinctions between high- and low-rated papers? General and specific text characteristics within three critical sections of the technical paper are identified and analyzed (Observations, Interpretations, Conclusions). Specific text characteristics consist of typical types of figures displayed in the papers, and typical statements within each paper section. Data gathering consisted of collecting 15 student papers which constitute the population of study. An analytical method was designed to manage and analyze the text characteristics. It has three stages: identifying coding categories, re-formulating the categories, and configuring categories. Three important elements emerged that identified notable distinctions in paper quality: data display and use, narration of complex geological feature relationships, and overall organization of text structure. An inter-rater coding concordance check was conducted, and showed high concordance ratios for the coding of each section: Observations = 0.95; Interpretations = 0.93; and Conclusions = 0.87. These categories collectively reveal a larger pattern of general differences in the paper quality levels (high, low, medium). This variation in the quality of papers demonstrates degrees of systematic thoroughness, which is defined as how systematically each student engages in the tasks of the assignment, and how thoroughly and consistently the student follows through on that systematic

Hydrogen Delivery Technical Team Roadmap

Energy Technology Data Exchange (ETDEWEB)

None

2013-06-01

The mission of the Hydrogen Delivery Technical Team (HDTT) is to enable the development of hydrogen delivery technologies, which will allow for fuel cell competitiveness with gasoline and hybrid technologies by achieving an as-produced, delivered, and dispensed hydrogen cost of $2-$4 per gallon of gasoline equivalent of hydrogen.

Hierarchical cluster analysis of technical replicates to identify interferents in untargeted mass spectrometry metabolomics.

Science.gov (United States)

Caesar, Lindsay K; Kvalheim, Olav M; Cech, Nadja B

2018-08-27

Mass spectral data sets often contain experimental artefacts, and data filtering prior to statistical analysis is crucial to extract reliable information. This is particularly true in untargeted metabolomics analyses, where the analyte(s) of interest are not known a priori. It is often assumed that chemical interferents (i.e. solvent contaminants such as plasticizers) are consistent across samples, and can be removed by background subtraction from blank injections. On the contrary, it is shown here that chemical contaminants may vary in abundance across each injection, potentially leading to their misidentification as relevant sample components. With this metabolomics study, we demonstrate the effectiveness of hierarchical cluster analysis (HCA) of replicate injections (technical replicates) as a methodology to identify chemical interferents and reduce their contaminating contribution to metabolomics models. Pools of metabolites with varying complexity were prepared from the botanical Angelica keiskei Koidzumi and spiked with known metabolites. Each set of pools was analyzed in triplicate and at multiple concentrations using ultraperformance liquid chromatography coupled to mass spectrometry (UPLC-MS). Before filtering, HCA failed to cluster replicates in the data sets. To identify contaminant peaks, we developed a filtering process that evaluated the relative peak area variance of each variable within triplicate injections. These interferent peaks were found across all samples, but did not show consistent peak area from injection to injection, even when evaluating the same chemical sample. This filtering process identified 128 ions that appear to originate from the UPLC-MS system. Data sets collected for a high number of pools with comparatively simple chemical composition were highly influenced by these chemical interferents, as were samples that were analyzed at a low concentration. When chemical interferent masses were removed, technical replicates clustered in

C. Rubbia's hybrid plant concept: a preliminary technical and economic analysis

International Nuclear Information System (INIS)

Bacher, P.

1999-01-01

The long term development of nuclear energy depends, inter alia, on the ability to use the abundant fertile materials (238U and/or thorium) and on an accepted management of the long-lived radioactive wastes. In order to meet both these objectives, C. Rubbia has presented a new version of an old concept: the hybrid reactor where a subcritical reactor is fed with neutrons produced by spallation. In his concept, the reactor is a molten lead cooled fast reactor, which can use either the uranium or the thorium cycle, and burn the minor actinides and some fission products. The present work is a preliminary and partial technical and economic analysis of the reactor part of C. Rubbia's proposal as they were set forth in a French Parliamentary audition in November 1996. The technical conclusions are that many of the design options proposed are not optimum and the uncertainties important, which is not particularly surprising at this stage of the concept. The economic 'guesstimate' yields a cost per kWh anywhere between one and two times that of a modern light water reactor, which is in contradiction with C. Rubbia's claims (half the cost.), but in a range which warrants more conceptual work before drawing any conclusions. Alternative design concepts are suggested. (orig.)

Relationship between non-technical skills and technical performance during cardiopulmonary resuscitation: does stress have an influence?

Science.gov (United States)

Krage, Ralf; Zwaan, Laura; Tjon Soei Len, Lian; Kolenbrander, Mark W; van Groeningen, Dick; Loer, Stephan A; Wagner, Cordula; Schober, Patrick

2017-11-01

Non-technical skills, such as task management, leadership, situational awareness, communication and decision-making refer to cognitive, behavioural and social skills that contribute to safe and efficient team performance. The importance of these skills during cardiopulmonary resuscitation (CPR) is increasingly emphasised. Nonetheless, the relationship between non-technical skills and technical performance is poorly understood. We hypothesise that non-technical skills become increasingly important under stressful conditions when individuals are distracted from their tasks, and investigated the relationship between non-technical and technical skills under control conditions and when external stressors are present. In this simulator-based randomised cross-over study, 30 anaesthesiologists and anaesthesia residents from the VU University Medical Center, Amsterdam, the Netherlands, participated in two different CPR scenarios in random order. In one scenario, external stressors (radio noise and a distractive scripted family member) were added, while the other scenario without stressors served as control condition. Non-technical performance of the team leader and technical performance of the team were measured using the 'Anaesthetists' Non-technical Skill' score and a recently developed technical skills score. Analysis of variance and Pearson correlation coefficients were used for statistical analyses. Non-technical performance declined when external stressors were present (adjusted mean difference 3.9 points, 95% CI 2.4 to 5.5 points). A significant correlation between non-technical and technical performance scores was observed when external stressors were present (r=0.67, 95% CI 0.40 to 0.83, ptechnical performance score (task management, team working, situation awareness, decision-making). During CPR with external stressors, the team's technical performance is related to the non-technical skills of the team leader. This may have important implications for training of

IFMIF - Layout and arrangement of cells according to requirements of technical logistics, reliability and remote handling

Energy Technology Data Exchange (ETDEWEB)

Mittwollen, Martin, E-mail: martin.mittwollen@kit.edu [Karlsruhe Institute of Technology, Institute for Conveying Technology and Logistics, Karlsruhe (Germany); Eilert, Dirk; Kubaschewski, Martin; Madzharov, Vladimir [Karlsruhe Institute of Technology, Institute for Conveying Technology and Logistics, Karlsruhe (Germany); Tian Kuo [Karlsruhe Institute of Technology, Institute for Neutron Physics and Reactor Technology, Karlsruhe (Germany)

2012-08-15

Highlights: Black-Right-Pointing-Pointer In a first approach, layout and arrangement of the cells followed a predetermined plant layout. Black-Right-Pointing-Pointer Disadvantages in technical logistics, reliability and remote handling have been detected. Black-Right-Pointing-Pointer Deliberation with project teams opened space for improvements. Black-Right-Pointing-Pointer Layout and arrangement of cells have been improved by simplification of design. Black-Right-Pointing-Pointer Speed and reliability have been increased significantly. - Abstract: The International Fusion Material Irradiation Facility (IFMIF) is designed to study and qualify structural and functional materials which shall be used in future fusion nuclear power plants. During the current engineering validation and engineering design activities (EVEDA) phase the development of e.g. an optimized layout and arrangement of the cells (Access Cell, Test Cell, and Test Module Handling Cells) is of major interest. After defining different functions for the individual cells like e.g. large scale/fine scale disassembling of test modules a first layout has been developed. This design followed requirements like having a minimum of carrier changes to avoid sources of failures. On the other hand it has had to be a compact arrangement of cells due to restrictions from plant layout. A row of changes of transfer direction, and different crane systems were the consequence. Constructive discussion with project team results in the statement, that for reasons of being reliable and fast, layout and arrangement of cells goes first, plant layout then will follow. The chance for big improvements was taken and the result was a simplified design with strong reduced number of functional elements, and increased reliability and speed.

Micro and nano-platforms for biological cell analysis

DEFF Research Database (Denmark)

Svendsen, Winnie Edith; Castillo, Jaime; Moresco, Jacob Lange

2011-01-01

In this paper some technological platforms developed for biological cell analysis will be presented and compared to existing systems. In brief, we present a novel micro cell culture chamber based on diffusion feeding of cells, into which cells can be introduced and extracted after culturing using...... from the cells, while passive modifications involve the presence of a peptide nanotube based scaffold for the cell culturing that mimics the in vivo environment. Two applications involving fluorescent in situ hybridization (FISH) analysis and cancer cell sorting are presented, as examples of further...... analysis that can be done after cell culturing. A platform able to automate the entire process from cell culturing to cell analysis by means of simple plug and play of various self-contained, individually fabricated modules is finally described....

Classification of Non-Small Cell Lung Cancer Using Significance Analysis of Microarray-Gene Set Reduction Algorithm

Directory of Open Access Journals (Sweden)

Lei Zhang

2016-01-01

Full Text Available Among non-small cell lung cancer (NSCLC, adenocarcinoma (AC, and squamous cell carcinoma (SCC are two major histology subtypes, accounting for roughly 40% and 30% of all lung cancer cases, respectively. Since AC and SCC differ in their cell of origin, location within the lung, and growth pattern, they are considered as distinct diseases. Gene expression signatures have been demonstrated to be an effective tool for distinguishing AC and SCC. Gene set analysis is regarded as irrelevant to the identification of gene expression signatures. Nevertheless, we found that one specific gene set analysis method, significance analysis of microarray-gene set reduction (SAMGSR, can be adopted directly to select relevant features and to construct gene expression signatures. In this study, we applied SAMGSR to a NSCLC gene expression dataset. When compared with several novel feature selection algorithms, for example, LASSO, SAMGSR has equivalent or better performance in terms of predictive ability and model parsimony. Therefore, SAMGSR is a feature selection algorithm, indeed. Additionally, we applied SAMGSR to AC and SCC subtypes separately to discriminate their respective stages, that is, stage II versus stage I. Few overlaps between these two resulting gene signatures illustrate that AC and SCC are technically distinct diseases. Therefore, stratified analyses on subtypes are recommended when diagnostic or prognostic signatures of these two NSCLC subtypes are constructed.

Designing socio-technical systems : Structures and processes

NARCIS (Netherlands)

Bots, P.W.G.; Van Daalen, C.

2012-01-01

The Systems Engineering, Policy Analysis and Management (SEPAM) MSc curriculum taught at Delft University of Technology focuses on the design of socio-technical systems (STS). We teach our students to structure design activities by considering what we call the TIP aspects: Technical systems,

KSC Technical Capabilities Website

Science.gov (United States)

Nufer, Brian; Bursian, Henry; Brown, Laurette L.

2010-01-01

This document is the website pages that review the technical capabilities that the Kennedy Space Center (KSC) has for partnership opportunities. The purpose of this information is to make prospective customers aware of the capabilities and provide an opportunity to form relationships with the experts at KSC. The technical capabilities fall into these areas: (1) Ground Operations and Processing Services, (2) Design and Analysis Solutions, (3) Command and Control Systems / Services, (4) Materials and Processes, (5) Research and Technology Development and (6) Laboratories, Shops and Test Facilities.

Transformation of technical infrastructure

DEFF Research Database (Denmark)

Nielsen, Susanne Balslev

, the evolution of large technological systems and theories about organisational and technological transformationprocesses. The empirical work consist of three analysis at three different levels: socio-technical descriptions of each sector, an envestigation of one municipality and envestigations of one workshop......The scope of the project is to investigate the possibillities of - and the barriers for a transformation of technical infrastructure conserning energy, water and waste. It focus on urban ecology as a transformation strategy. The theoretical background of the project is theories about infrastructure...

Technical considerations on scanning and image analysis for amyloid PET in dementia

International Nuclear Information System (INIS)

Akamatsu, Go; Ohnishi, Akihito; Aita, Kazuki; Ikari, Yasuhiko; Senda, Michio; Yamamoto, Yasuji

2017-01-01

Brain imaging techniques, such as computed tomography (CT), magnetic resonance imaging (MRI), single photon emission computed tomography (SPECT), and positron emission tomography (PET), can provide essential and objective information for the early and differential diagnosis of dementia. Amyloid PET is especially useful to evaluate the amyloid-β pathological process as a biomarker of Alzheimer's disease. This article reviews critical points about technical considerations on the scanning and image analysis methods for amyloid PET. Each amyloid PET agent has its own proper administration instructions and recommended uptake time, scan duration, and the method of image display and interpretation. In addition, we have introduced general scanning information, including subject positioning, reconstruction parameters, and quantitative and statistical image analysis. We believe that this article could make amyloid PET a more reliable tool in clinical study and practice. (author)

Technical Considerations on Scanning and Image Analysis for Amyloid PET in Dementia.

Science.gov (United States)

Akamatsu, Go; Ohnishi, Akihito; Aita, Kazuki; Ikari, Yasuhiko; Yamamoto, Yasuji; Senda, Michio

2017-01-01

Brain imaging techniques, such as computed tomography (CT), magnetic resonance imaging (MRI), single photon emission computed tomography (SPECT), and positron emission tomography (PET), can provide essential and objective information for the early and differential diagnosis of dementia. Amyloid PET is especially useful to evaluate the amyloid-β pathological process as a biomarker of Alzheimer's disease. This article reviews critical points about technical considerations on the scanning and image analysis methods for amyloid PET. Each amyloid PET agent has its own proper administration instructions and recommended uptake time, scan duration, and the method of image display and interpretation. In addition, we have introduced general scanning information, including subject positioning, reconstruction parameters, and quantitative and statistical image analysis. We believe that this article could make amyloid PET a more reliable tool in clinical study and practice.

Marketing information: The technical report as product

Science.gov (United States)

Stoher, F. F.; Pinelli, T. E.

1981-01-01

Technical reports constitute a product, the primary means for communicating the results of research to the user. The Langley scientific and technical information (STI) review and evaluation project undertook a review of the technical report as an effective product for information communication. Style manuals describing theory and practice in technical report preparation; publication manuals covering such factors as design, layout, and type style; and copies of technical reports were obtained from industrial, academic, governmental, and research organizations. Based on an analysis of this material, criteria will be established for the report components, for the relationship of the components within the report context, and for the overall report organization. The criteria will be used as bench marks and compared with the publication standards currently used to prepare NASA technical reports.

ATR Technical Specification Upgrade Program

International Nuclear Information System (INIS)

McCracken, R.T.; Durney, J.L.; Freund, G.A.

1990-01-01

The Advanced Test Reactor (ATR) is a 250 MW, uranium-aluminum fueled test reactor which began full power operation in 1969. The initial operation was controlled by an Operating Limits document based on the original Safety Analysis Report. Additional safety bases were later developed to support Technical Specifications which were approved and implemented in 1977. The Technical Specifications which were initially developed with content and format specified in ANSI/ANS--15.1, ''The Development of Technical Specifications for Research Reactors.'' The safety basis documentation and the Technical Specifications have been updated as required to maintain them current with the ATR facility configuration. All revisions have been made with a content, format and style consistent with the original. A major, two-phase program to upgrade the content, format and style is in progress. This paper describes the first phase of this program

Vehicle Integrated Performance Analysis, the VIPA Experience: Reconnecting with Technical Integration

Science.gov (United States)

McGhee, David S.

2005-01-01

Today's NASA is facing significant challenges and changes. The Exploration initiative indicates a large increase in projects with limited increase in budget. The Columbia report has criticized NASA for its lack of insight and technical integration impacting its ability to provide safety. The Aldridge report is advocating NASA find new ways of doing business. Very early in the Space Launch Initiative (SLI) program a small team of engineers at MSFC were asked to propose a process for performing a system level assessment of a launch vehicle. The request was aimed primarily at providing insight and making NASA a "smart buyer." Out of this effort the VIPA team was created. The difference between the VIPA effort and many integration attempts is that VIPA focuses on using experienced people from various disciplines and a process which focuses them on a technically integrated assessment. Most previous attempts have focused on developing an all encompassing software tool. In addition, VIPA anchored its process formulation in the experience of its members and in early developmental Space Shuttle experience. The primary reference for this is NASA-TP-2001-210092, "Launch Vehicle Design Process: Characterization, Technical Integration, and Lessons Learned," and discussions with its authors. The foundations of VIPA's process are described. The VIPA team also recognized the need to drive detailed analysis earlier in the design process. Analyses and techniques typically done in later design phases, are brought forward using improved computing technology. The intent is to allow the identification of significant sensitivities, trades, and design issues much earlier in the program. This process is driven by the T-model for Technical Integration described in the aforementioned reference. VIPA's approach to performing system level technical integration is discussed in detail. Proposed definitions are offered to clarify this discussion and the general systems integration dialog. VIPA

Deconstructing stem cell population heterogeneity: Single-cell analysis and modeling approaches

Science.gov (United States)

Wu, Jincheng; Tzanakakis, Emmanuel S.

2014-01-01

Isogenic stem cell populations display cell-to-cell variations in a multitude of attributes including gene or protein expression, epigenetic state, morphology, proliferation and proclivity for differentiation. The origins of the observed heterogeneity and its roles in the maintenance of pluripotency and the lineage specification of stem cells remain unclear. Addressing pertinent questions will require the employment of single-cell analysis methods as traditional cell biochemical and biomolecular assays yield mostly population-average data. In addition to time-lapse microscopy and flow cytometry, recent advances in single-cell genomic, transcriptomic and proteomic profiling are reviewed. The application of multiple displacement amplification, next generation sequencing, mass cytometry and spectrometry to stem cell systems is expected to provide a wealth of information affording unprecedented levels of multiparametric characterization of cell ensembles under defined conditions promoting pluripotency or commitment. Establishing connections between single-cell analysis information and the observed phenotypes will also require suitable mathematical models. Stem cell self-renewal and differentiation are orchestrated by the coordinated regulation of subcellular, intercellular and niche-wide processes spanning multiple time scales. Here, we discuss different modeling approaches and challenges arising from their application to stem cell populations. Integrating single-cell analysis with computational methods will fill gaps in our knowledge about the functions of heterogeneity in stem cell physiology. This combination will also aid the rational design of efficient differentiation and reprogramming strategies as well as bioprocesses for the production of clinically valuable stem cell derivatives. PMID:24035899

A hybrid stock trading framework integrating technical analysis with machine learning techniques

Directory of Open Access Journals (Sweden)

Rajashree Dash

2016-03-01

Full Text Available In this paper, a novel decision support system using a computational efficient functional link artificial neural network (CEFLANN and a set of rules is proposed to generate the trading decisions more effectively. Here the problem of stock trading decision prediction is articulated as a classification problem with three class values representing the buy, hold and sell signals. The CEFLANN network used in the decision support system produces a set of continuous trading signals within the range 0–1 by analyzing the nonlinear relationship exists between few popular technical indicators. Further the output trading signals are used to track the trend and to produce the trading decision based on that trend using some trading rules. The novelty of the approach is to engender the profitable stock trading decision points through integration of the learning ability of CEFLANN neural network with the technical analysis rules. For assessing the potential use of the proposed method, the model performance is also compared with some other machine learning techniques such as Support Vector Machine (SVM, Naive Bayesian model, K nearest neighbor model (KNN and Decision Tree (DT model.

IFMIF – Layout and arrangement of cells according to requirements of technical logistics, reliability and remote handling

International Nuclear Information System (INIS)

Mittwollen, Martin; Eilert, Dirk; Kubaschewski, Martin; Madzharov, Vladimir; Tian Kuo

2012-01-01

Highlights: ► In a first approach, layout and arrangement of the cells followed a predetermined plant layout. ► Disadvantages in technical logistics, reliability and remote handling have been detected. ► Deliberation with project teams opened space for improvements. ► Layout and arrangement of cells have been improved by simplification of design. ► Speed and reliability have been increased significantly. - Abstract: The International Fusion Material Irradiation Facility (IFMIF) is designed to study and qualify structural and functional materials which shall be used in future fusion nuclear power plants. During the current engineering validation and engineering design activities (EVEDA) phase the development of e.g. an optimized layout and arrangement of the cells (Access Cell, Test Cell, and Test Module Handling Cells) is of major interest. After defining different functions for the individual cells like e.g. large scale/fine scale disassembling of test modules a first layout has been developed. This design followed requirements like having a minimum of carrier changes to avoid sources of failures. On the other hand it has had to be a compact arrangement of cells due to restrictions from plant layout. A row of changes of transfer direction, and different crane systems were the consequence. Constructive discussion with project team results in the statement, that for reasons of being reliable and fast, layout and arrangement of cells goes first, plant layout then will follow. The chance for big improvements was taken and the result was a simplified design with strong reduced number of functional elements, and increased reliability and speed.

A data envelope analysis to assess factors affecting technical and economic efficiency of individual broiler breeder hens.

Science.gov (United States)

Romero, L F; Zuidhof, M J; Jeffrey, S R; Naeima, A; Renema, R A; Robinson, F E

2010-08-01

This study evaluated the effect of feed allocation and energetic efficiency on technical and economic efficiency of broiler breeder hens using the data envelope analysis methodology and quantified the effect of variables affecting technical efficiency. A total of 288 Ross 708 pullets were placed in individual cages at 16 wk of age and assigned to 1 of 4 feed allocation groups. Three of them had feed allocated on a group basis with divergent BW targets: standard, high (standard x 1.1), and low (standard x 0.9). The fourth group had feed allocated on an individual bird basis following the standard BW target. Birds were classified in 3 energetic efficiency categories: low, average, and high, based on estimated maintenance requirements. Technical efficiency considered saleable chicks as output and cumulative ME intake and time as inputs. Economic efficiency of feed allocation treatments was analyzed under different cost scenarios. Birds with low feed allocation exhibited a lower technical efficiency (69.4%) than standard (72.1%), which reflected a reduced egg production rate. Feed allocation of the high treatment could have been reduced by 10% with the same chick production as the standard treatment. The low treatment exhibited reduced economic efficiency at greater capital costs, whereas high had reduced economic efficiency at greater feed costs. The average energetic efficiency hens had a lower technical efficiency in the low compared with the standard feed allocation. A 1% increment in estimated maintenance requirement changed technical efficiency by -0.23%, whereas a 1% increment in ME intake had a -0.47% effect. The negative relationship between technical efficiency and ME intake was counterbalanced by a positive correlation of ME intake and egg production. The negative relationship of technical efficiency and maintenance requirements was synergized by a negative correlation of hen maintenance and egg production. Economic efficiency methodologies are effective

The Technical Analysis of the Impact of Circuit of Financial Capital on the Currency Stability in Ukraine

Directory of Open Access Journals (Sweden)

Iaroshevska Oksana V.

2018-01-01

Full Text Available The relevance of the article’s topic is determined by the aggravation of the monetary and financial crisis in Ukraine and the need to overcome imbalances arising from the complications of circuit of financial capital and its involvement by economic entities. The article is aimed at researching on the basis of technical analysis the influence of exchange rate factor on the formation of capital in the country. The general and distinctive features of technical and fundamental analysis of currency markets are defined. It is shown that despite the difference of views, technical analysis is an integral stage of forecasting the exchange rate. The main scientific result of the article is substantiating the temporary lags of fractals, which explain the change in the dynamics of the exchange rate and their impact on the circuit of financial capital. It has been proved that the systemic crisis in the currency market of Ukraine arose during 2012–2014, with its peak at the end of the specified period. To stop devaluation processes and to provide measures on regulation of the foreign exchange market it has been proposed to soften the conditions of doing business, to improve the methodology of quantitative and qualitative forecasting of the NBU exchange rates, to form system of foreign exchange risk insurance instruments, to increase international reserves to a secure level, etc. Prospect for further research is determining the impact of currency fluctuations on the financial performance of the use of capital of Ukrainian economic entities.

Waste management project technical baseline description

International Nuclear Information System (INIS)

Sederburg, J.P.

1997-01-01

A systems engineering approach has been taken to describe the technical baseline under which the Waste Management Project is currently operating. The document contains a mission analysis, function analysis, requirement analysis, interface definitions, alternative analysis, system definition, documentation requirements, implementation definitions, and discussion of uncertainties facing the Project

Proceedings of the workshop on structural analysis needs for magnetic fusion energy superconducting magnets: a technical assessment

International Nuclear Information System (INIS)

Reich, M.; Lehner, J.; Powell, J.; Bezler, P.

1976-01-01

The technical portions of the meeting were divided into three major sessions as follows: (1) Review of methods being presently used by the MFE community for structural evaluation of current designs. (2) Future structural analysis needs. (3) Open discussions dealing with adequacy of present methods, the improvements needed for MFE magnet structural analysis, and the establishment of an MFE magnet structural advisory group. Summaries of the individual talks are presented

Proceedings of the workshop on structural analysis needs for magnetic fusion energy superconducting magnets: a technical assessment

Energy Technology Data Exchange (ETDEWEB)

Reich, M.; Lehner, J.; Powell, J.; Bezler, P.

1976-01-01

The technical portions of the meeting were divided into three major sessions as follows: (1) Review of methods being presently used by the MFE community for structural evaluation of current designs. (2) Future structural analysis needs. (3) Open discussions dealing with adequacy of present methods, the improvements needed for MFE magnet structural analysis, and the establishment of an MFE magnet structural advisory group. Summaries of the individual talks are presented.

Development of Cell Analysis Software for Cultivated Corneal Endothelial Cells.

Science.gov (United States)

Okumura, Naoki; Ishida, Naoya; Kakutani, Kazuya; Hongo, Akane; Hiwa, Satoru; Hiroyasu, Tomoyuki; Koizumi, Noriko

2017-11-01

To develop analysis software for cultured human corneal endothelial cells (HCECs). Software was designed to recognize cell borders and to provide parameters such as cell density, coefficient of variation, and polygonality of cultured HCECs based on phase contrast images. Cultured HCECs with high or low cell density were incubated with Ca-free and Mg-free phosphate-buffered saline for 10 minutes to reveal the cell borders and were then analyzed with software (n = 50). Phase contrast images showed that cell borders were not distinctly outlined, but these borders became more distinctly outlined after phosphate-buffered saline treatment and were recognized by cell analysis software. The cell density value provided by software was similar to that obtained using manual cell counting by an experienced researcher. Morphometric parameters, such as the coefficient of variation and polygonality, were also produced by software, and these values were significantly correlated with cell density (Pearson correlation coefficients -0.62 and 0.63, respectively). The software described here provides morphometric information from phase contrast images, and it enables subjective and noninvasive quality assessment for tissue engineering therapy of the corneal endothelium.

FY 2016 Grant Announcement: FY 2016 Technical Analysis and Programmatic Evaluation Support to the Chesapeake Bay Program Partnership

Science.gov (United States)

The U.S. Environmental Protection Agency’s Chesapeake Bay Program Office is announcing a Request for Proposals for applicants to provide the Chesapeake Bay Program partners with a proposal(s) for providing technical analysis and programmatic evaluation

FHWA vehicle crash analysis conference proceedings : technical summary

Science.gov (United States)

1997-04-01

This technical summary announces the publication of conference proceedings as a Federal Highway Administration (FHWA) report (FHWA-RD-96-212) of the same title. The report represents a compilation of seven research papers presented at The FHWA Veh...

Technical Requirements Analysis and Control Systems (TRACS) Initial Operating Capability (IOC) documentation

Science.gov (United States)

Hammond, Dana P.

1991-01-01

The Technical Requirements Analysis and Control Systems (TRACS) software package is described. TRACS offers supplemental tools for the analysis, control, and interchange of project requirements. This package provides the fundamental capability to analyze and control requirements, serves a focal point for project requirements, and integrates a system that supports efficient and consistent operations. TRACS uses relational data base technology (ORACLE) in a stand alone or in a distributed environment that can be used to coordinate the activities required to support a project through its entire life cycle. TRACS uses a set of keyword and mouse driven screens (HyperCard) which imposes adherence through a controlled user interface. The user interface provides an interactive capability to interrogate the data base and to display or print project requirement information. TRACS has a limited report capability, but can be extended with PostScript conventions.

[Hepatic cell transplantation. Technical and methodological aspects].

Science.gov (United States)

Pareja, Eugenia; Martínez, Amparo; Cortés, Miriam; Bonora, Ana; Moya, Angel; Sanjuán, Fernando; Gómez-Lechón, M José; Mir, José

2010-03-01

Hepatic cell transplantation consists of grafting already differentiated cells such as hepatocytes. Human hepatocytes are viable and functionally active. Liver cell transplantation is carried out by means of a 3-step method: isolation of hepatocytes from donor liver rejected for orthotopic transplantation, preparing a cell suspension for infusion and, finally, hepatocytes are implanted into the recipient. There are established protocols for the isolation of human hepatocytes from unused segments of donor livers, based on collagenase digestion of cannulated liver tissue at 37 degrees C. The hepatocytes can be used fresh or cryopreserved. Cryopreservation of isolated human hepatocytes would then be available for planned use. In cell transplant, the important aspects are: infusion route, number of cells, number of infusions and viability of the cells. The cells are infused into the patient through a catheter inserted via portal vein or splenic artery. Liver cell transplantation allows liver tissue to be used that would, otherwise, be discarded, enabling multiple patients to be treated with hepatocytes from a single tissue donor. Copyright 2009 AEC. Published by Elsevier Espana. All rights reserved.

ERLN Technical Support for Labs

Science.gov (United States)

The Environmental Response Laboratory Network provides policies and guidance on lab and data requirements, Standardized Analytical Methods, and technical support for water and radiological sampling and analysis

COMPARATIVE ANALYSIS OF TECHNICAL IDICATORS AND TACTICAL UTILITY OF THEIR APPLICATION IN FOOTBALL

Directory of Open Access Journals (Sweden)

Peko Vujović

2010-09-01

Full Text Available The aim of the research is to ascertain the manifested differences in the inner structure of the game and to establish and notify the tendencies of football game development movement by a comparative analysis, according to the manifested differences that examined according to the technical and tactics characteristics. The specimen is representative, thus the research includes the most successful national teams (semi-final and final on XVI, XVII and XVIII World Football Championship. The analysis includes offensive playing, movements of certain players during the game, the way in which the ball is passed, the goalkeeper’s performance... This research has once again proved the presence of permanent further tendencies of movement of the contemporary top-level football.

Technical approach document

International Nuclear Information System (INIS)

1989-12-01

The Uranium Mill Tailings Radiation Control Act (UMTRCA) of 1978, Public Law 95-604 (PL95-604), grants the Secretary of Energy the authority and responsibility to perform such actions as are necessary to minimize radiation health hazards and other environmental hazards caused by inactive uranium mill sites. This Technical Approach Document (TAD) describes the general technical approaches and design criteria adopted by the US Department of Energy (DOE) in order to implement remedial action plans (RAPS) and final designs that comply with EPA standards. It does not address the technical approaches necessary for aquifer restoration at processing sites; a guidance document, currently in preparation, will describe aquifer restoration concerns and technical protocols. This document is a second revision to the original document issued in May 1986; the revision has been made in response to changes to the groundwater standards of 40 CFR 192, Subparts A--C, proposed by EPA as draft standards. New sections were added to define the design approaches and designs necessary to comply with the groundwater standards. These new sections are in addition to changes made throughout the document to reflect current procedures, especially in cover design, water resources protection, and alternate site selection; only minor revisions were made to some of the sections. Sections 3.0 is a new section defining the approach taken in the design of disposal cells; Section 4.0 has been revised to include design of vegetated covers; Section 8.0 discusses design approaches necessary for compliance with the groundwater standards; and Section 9.0 is a new section dealing with nonradiological hazardous constituents. 203 refs., 18 figs., 26 tabs

Local cell metrics: a novel method for analysis of cell-cell interactions

Directory of Open Access Journals (Sweden)

Chen Chien-Chiang

2009-10-01

Full Text Available Abstract Background The regulation of many cell functions is inherently linked to cell-cell contact interactions. However, effects of contact interactions among adherent cells can be difficult to detect with global summary statistics due to the localized nature and noise inherent to cell-cell interactions. The lack of informatics approaches specific for detecting cell-cell interactions is a limitation in the analysis of large sets of cell image data, including traditional and combinatorial or high-throughput studies. Here we introduce a novel histogram-based data analysis strategy, termed local cell metrics (LCMs, which addresses this shortcoming. Results The new LCM method is demonstrated via a study of contact inhibition of proliferation of MC3T3-E1 osteoblasts. We describe how LCMs can be used to quantify the local environment of cells and how LCMs are decomposed mathematically into metrics specific to each cell type in a culture, e.g., differently-labelled cells in fluorescence imaging. Using this approach, a quantitative, probabilistic description of the contact inhibition effects in MC3T3-E1 cultures has been achieved. We also show how LCMs are related to the naïve Bayes model. Namely, LCMs are Bayes class-conditional probability functions, suggesting their use for data mining and classification. Conclusion LCMs are successful in robust detection of cell contact inhibition in situations where conventional global statistics fail to do so. The noise due to the random features of cell behavior was suppressed significantly as a result of the focus on local distances, providing sensitive detection of cell-cell contact effects. The methodology can be extended to any quantifiable feature that can be obtained from imaging of cell cultures or tissue samples, including optical, fluorescent, and confocal microscopy. This approach may prove useful in interpreting culture and histological data in fields where cell-cell interactions play a critical

Local cell metrics: a novel method for analysis of cell-cell interactions.

Science.gov (United States)

Su, Jing; Zapata, Pedro J; Chen, Chien-Chiang; Meredith, J Carson

2009-10-23

The regulation of many cell functions is inherently linked to cell-cell contact interactions. However, effects of contact interactions among adherent cells can be difficult to detect with global summary statistics due to the localized nature and noise inherent to cell-cell interactions. The lack of informatics approaches specific for detecting cell-cell interactions is a limitation in the analysis of large sets of cell image data, including traditional and combinatorial or high-throughput studies. Here we introduce a novel histogram-based data analysis strategy, termed local cell metrics (LCMs), which addresses this shortcoming. The new LCM method is demonstrated via a study of contact inhibition of proliferation of MC3T3-E1 osteoblasts. We describe how LCMs can be used to quantify the local environment of cells and how LCMs are decomposed mathematically into metrics specific to each cell type in a culture, e.g., differently-labelled cells in fluorescence imaging. Using this approach, a quantitative, probabilistic description of the contact inhibition effects in MC3T3-E1 cultures has been achieved. We also show how LCMs are related to the naïve Bayes model. Namely, LCMs are Bayes class-conditional probability functions, suggesting their use for data mining and classification. LCMs are successful in robust detection of cell contact inhibition in situations where conventional global statistics fail to do so. The noise due to the random features of cell behavior was suppressed significantly as a result of the focus on local distances, providing sensitive detection of cell-cell contact effects. The methodology can be extended to any quantifiable feature that can be obtained from imaging of cell cultures or tissue samples, including optical, fluorescent, and confocal microscopy. This approach may prove useful in interpreting culture and histological data in fields where cell-cell interactions play a critical role in determining cell fate, e.g., cancer, developmental

1980 Annual status report: provision of scientific and technical services

International Nuclear Information System (INIS)

1981-01-01

Two kinds of objectives are pursued at the JRC in direct support of the various General Directorates of the Commission: Technical Evaluations where system analysis techniques are mainly employed and Technical Assistance where laboratory measurement, technical expertises and management of projects are provided

Critical Analysis of the Quality, Readability, and Technical Aspects of Online Information Provided for Neck-Lifts.

Science.gov (United States)

Rayess, Hani; Zuliani, Giancarlo F; Gupta, Amar; Svider, Peter F; Folbe, Adam J; Eloy, Jean Anderson; Carron, Michael A

2017-03-01

The number of patients using the internet to obtain health information is growing. This material is unregulated and heterogeneous and can influence patient decisions. To compare the quality, readability, and technical aspects of online information about neck-lifts provided by private practice websites vs academic medical centers and reference sources. In this cross-sectional analysis conducted between November 2015 and January 2016, a Google search of the term neck-lift was performed, and the first 45 websites were evaluated. The websites were categorized as private practice vs other. Private websites (PWs) included sites created by private practice physicians. Other websites (OWs) were created by academic medical centers or reference sources. Quality, readability, and technical aspects of online websites related to neck-lifts. Quality was assessed using the DISCERN criteria and the Health on the Net principles (HONcode). Readability was assessed using 7 validated and widely used criteria. Consensus US reading grade level readability was provided by a website (readabilityformulas.com). Twelve technical aspects were evaluated based on criteria specified by medical website creators. Forty-five websites (8 OWs [18%] and 37 PWs [82%]) were analyzed. There was a significant difference in quality between OWs and PWs based on the DISCERN criteria and HONcode principles. The DISCERN overall mean (SD) scores were 2.3 (0.5) for OWs and 1.3 (0.3) for PWs (P analysis, the mean (SD) was 8.6 (1.8) (range, 5-11) for OW, and the mean (SD) was 5.8 (1.7) (range, 2-9) for PW. The mean (SD) readability consensus reading grade level scores were 11.7 (1.9) for OWs and 10.6 (1.9) for PWs. Of a total possible score of 12, the mean (SD) technical scores were 6.3 (1.8) (range, 4-9) for OWs and 6.4 (1.5) (range, 3-9) for PWs. Compared with PWs, OWs had a significantly higher quality score based on both the DISCERN criteria and HONcode principles. The mean readability for OWs and PWs was

Engineering and Technical Education in Russia, in Numbers

Science.gov (United States)

Aref'ev, A. L.; Aref'ev, M. A.

2013-01-01

An analysis of the main tendencies in the development of engineering and technical education in Russia during the last 100 years shows that earlier strengths have been lost, and that currently technical education in Russia is far behind modern world standards.

A review and evaluation of the Langley Research Center's Scientific and Technical Information Program: Results of phase 6: The technical report. A survey and analysis

Science.gov (United States)

Mccullough, R. A.; Pinelli, T. E.; Pilley, D. D.; Stohrer, F. F.

1982-01-01

Current practice and usage using selected technical reports; literature relative to the sequential, language, and presentation components of technical reports; and NASA technical report publications standards are discussed. The effctiveness of the technical report as a product for information dissemination is considered.

Research on power market technical analysis index system employing high-low matching mechanism

Science.gov (United States)

Li, Tao; Wang, Shengyu

2018-06-01

The power market trading technical analysis refers to a method that takes the bidding behavior of members in the power market as the research object, sums up some typical market rules and price trends by applying mathematical and logical methods, and finally can effectively assist members in the power market to make more reasonable trading decisions. In this paper, the following four indicators have been proposed: bidding price difference scale, extreme bidding price rate, dispersion of bidding price and monthly transaction satisfaction of electricity trading, which are the core of the index system.

Analysis of scientific and technical production of IPEN-CNEN/SP in the period of 1984 to 1988

International Nuclear Information System (INIS)

Sugai, M.

1989-01-01

An analysis of scientific and technical production of Instituto de Pesquisas Energeticas e Nucleares - IPEN-CNEN/SP in the period of 1984 to 1988 is presented. It includes articles, dissertation, thesis, books, reports and papers presented in scientific meetings or published in the Publicacao IPEN series. (C.M.)

Technical efficiency of potato and dairy farming in mountainous Kazbegi district, Georgia

Directory of Open Access Journals (Sweden)

R. Shavgulidze

2017-03-01

Full Text Available The study employs a stochastic frontier analysis to assess technical efficiency of potato and cheese production and determine socio-economic factors that influence farmers' technical efficiency levels in mountainous Kazbegi district of Georgia. The study found improved feeding to be inversely related with technical inefficiency in cheese production. In potato production, the analysis revealed implementation of the plant protection measures and use of quality seeds to be significant aspects that influence technical efficiency of potato growers.

Guam Initial Technical Assessment Report

Energy Technology Data Exchange (ETDEWEB)

Baring-Gould, I.; Conrad, M.; Haase, S.; Hotchkiss, E.; McNutt, P.

2011-04-01

Under an interagency agreement, funded by the Department of Interior's (DOI) Office of Insular Affairs (OIA), the National Renewable Energy Laboratory (NREL) was tasked to deliver technical assistance to the island of Guam by conducting an island initial technical assessment that would lay out energy consumption and production data and establish a baseline. This assessment will be used to conduct future analysis and studies by NREL that will estimate energy efficiency and renewable energy potential for the island of Guam.

The SocioEconomic Analysis of Repository Siting (SEARS): Technical description: Final draft

International Nuclear Information System (INIS)

1984-11-01

Socioeconomic impacts must be assessed both for the near term and for the future. One means of addressing the need for the assessment of such impacts has been through the development of the computerized socioeconomic assessment model called the SocioEconomic Analysis of Repository Siting (SEARS) model. The SEARS model was developed for the Battelle Project Management Division. It was refined and adapted from state-of-the-art computerized projection models and thoroughly validated and is now available for use in projecting the likely socioeconomic impacts of a repository facility. This Technical Description is one of six major products that describe the SEARS modeling system. 61 refs., 11 figs., 9 tabs

Technical and economic analysis of the European electricity system with 60% RES

International Nuclear Information System (INIS)

Burtin, Alain; Silva, Vera

2015-01-01

This document examines the impacts of the integration of a large share of variable renewable generation into the generation mix of the European interconnected electricity system. The analysis, which is based on the results of long term studies performed by EDF R and D, aims at improving the current understanding of the technical and economic feasibility of a massive deployment of wind and PV across the European system. The document addresses several aspects of the system integration of variable generation in particular, including the characterization of variable RES generation, the need for generation and interconnection infrastructure, the impacts on short-term system operation and market profitability. (authors)

Nanoparticle Solar Cell Final Technical Report

Energy Technology Data Exchange (ETDEWEB)

Breeze, Alison, J; Sahoo, Yudhisthira; Reddy, Damoder; Sholin, Veronica; Carter, Sue

2008-06-17

The purpose of this work was to demonstrate all-inorganic nanoparticle-based solar cells with photovoltaic performance extending into the near-IR region of the solar spectrum as a pathway towards improving power conversion efficiencies. The field of all-inorganic nanoparticle-based solar cells is very new, with only one literature publication in the prior to our project. Very little is understood regarding how these devices function. Inorganic solar cells with IR performance have previously been fabricated using traditional methods such as physical vapor deposition and sputtering, and solution-processed devices utilizing IR-absorbing organic polymers have been investigated. The solution-based deposition of nanoparticles offers the potential of a low-cost manufacturing process combined with the ability to tune the chemical synthesis and material properties to control the device properties. This work, in collaboration with the Sue Carter research group at the University of California, Santa Cruz, has greatly expanded the knowledge base in this field, exploring multiple material systems and several key areas of device physics including temperature, bandgap and electrode device behavior dependence, material morphological behavior, and the role of buffer layers. One publication has been accepted to Solar Energy Materials and Solar Cells pending minor revision and another two papers are being written now. While device performance in the near-IR did not reach the level anticipated at the beginning of this grant, we did observe one of the highest near-IR efficiencies for a nanoparticle-based solar cell device to date. We also identified several key parameters of importance for improving both near-IR performance and nanoparticle solar cells in general, and demonstrated multiple pathways which showed promise for future commercialization with further research.

Savannah River Site sample and analysis plan for Clemson Technical Center waste

International Nuclear Information System (INIS)

Hagstrom, T.

1998-04-01

The purpose of this sampling and analysis plan is to determine the chemical, physical and radiological properties of the SRS radioactive Polychlorinated Biphenyl (PCB) liquid waste stream, to verify that it conforms to Waste Acceptance Criteria of the Department of Energy (DOE) East Tennessee Technology Park (ETTP) Toxic Substance Control Act (TSCA) Incineration Facility. Waste being sent to the ETTP TSCA Incinerator for treatment must be sufficiently characterized to ensure that the waste stream meets the waste acceptance criteria to ensure proper handling, classification, and processing of incoming waste to meet the Waste Storage and Treatment Facility's Operating Permits. This sampling and analysis plan is limited to WSRC container(s) of homogeneous or multiphasic radioactive PCB contaminated liquids generated in association with a treatability study at Clemson Technical Center (CTC) and currently stored at the WSRC Solid Waste Division Mixed Waste Storage Facility (MWSF)

Single cell analysis of normal and leukemic hematopoiesis.

Science.gov (United States)

Povinelli, Benjamin J; Rodriguez-Meira, Alba; Mead, Adam J

2018-02-01

The hematopoietic system is well established as a paradigm for the study of cellular hierarchies, their disruption in disease and therapeutic use in regenerative medicine. Traditional approaches to study hematopoiesis involve purification of cell populations based on a small number of surface markers. However, such population-based analysis obscures underlying heterogeneity contained within any phenotypically defined cell population. This heterogeneity can only be resolved through single cell analysis. Recent advances in single cell techniques allow analysis of the genome, transcriptome, epigenome and proteome in single cells at an unprecedented scale. The application of these new single cell methods to investigate the hematopoietic system has led to paradigm shifts in our understanding of cellular heterogeneity in hematopoiesis and how this is disrupted in disease. In this review, we summarize how single cell techniques have been applied to the analysis of hematopoietic stem/progenitor cells in normal and malignant hematopoiesis, with a particular focus on recent advances in single-cell genomics, including how these might be utilized for clinical application. Copyright © 2017. Published by Elsevier Ltd.

Paramedics' non-technical skills: a literature review.

Science.gov (United States)

Shields, Allan; Flin, Rhona

2013-05-01

Healthcare organisations have started to examine the impact that the human worker has on patient safety. Adopting the Crew Resource Management (CRM) approach, used in aviation, the CRM or non-technical skills of anaesthetists, surgeons, scrub practitioners and emergency physicians have recently been identified to assist in their training and assessment. Paramedics are exposed to dynamic and dangerous situations where patients have to be managed, often with life-threatening injuries or illness. As in other safety-critical domains, the technical skills of paramedics are complemented by effective non-technical skills. The aim of this paper was to review the literature on the non-technical (social and cognitive) skills used by paramedics. This review was undertaken as part of a task analysis to identify the non-technical skills used by paramedics. Of the seven papers reviewed, the results have shown very little research on this topic and so reveal a gap in the understanding of paramedic non-technical skills.

Proteomic Analysis of Chinese Hamster Ovary Cells

DEFF Research Database (Denmark)

Baycin-Hizal, Deniz; Tabb, David L.; Chaerkady, Raghothama

2012-01-01

To complement the recent genomic sequencing of Chinese hamster ovary (CHO) cells, proteomic analysis was performed on CHO cells including the cellular proteome, secretome, and glycoproteome using tandem mass spectrometry (MS/MS) of multiple fractions obtained from gel electrophoresis, multidimens......To complement the recent genomic sequencing of Chinese hamster ovary (CHO) cells, proteomic analysis was performed on CHO cells including the cellular proteome, secretome, and glycoproteome using tandem mass spectrometry (MS/MS) of multiple fractions obtained from gel electrophoresis...

Perspective on Cancer Therapeutics Utilizing Analysis of Circulating Tumor Cells

Directory of Open Access Journals (Sweden)

Keun-Yeong Jeong

2018-04-01

Full Text Available Various methods are available for cancer screening, and the methods are performed depending on the origin site of cancer. Among these methods, biopsy followed by medical imaging is the most common. After cancer progression is determined, an optimal treatment—such as surgery, chemotherapy, and/or radiation therapy—is selected. A new assay has been developed that detects circulating tumor cells (CTCs. Tracking changes in CTCs may reveal important tumoral sensitivity information or resistance patterns to specific regimens and prompt changes in therapy on a personalized basis. Characterization of CTCs at the DNA, RNA, and protein levels is important for gaining insight for clinical applications. A small number of CTCs can be analyzed to obtain genome information such as the progression of cancer including metastasis, even in a single cluster. Although many clinical studies, particularly CTC enumeration and detection of specific oncogene expression, have increased the success rate of diagnosis and predicting prognosis, there is no consensus regarding the technical approaches and various aspects of the methodology, making it difficult to standardize optimal methods for CTC analysis. However, ongoing technological advances are currently being achieved and large-scale clinical studies are being conducted. Applying CTC analysis in the clinic would be very useful for advancing diagnosis, prognosis prediction, and therapeutics.

Previously unidentified changes in renal cell carcinoma gene expression identified by parametric analysis of microarray data

International Nuclear Information System (INIS)

Lenburg, Marc E; Liou, Louis S; Gerry, Norman P; Frampton, Garrett M; Cohen, Herbert T; Christman, Michael F

2003-01-01

Renal cell carcinoma is a common malignancy that often presents as a metastatic-disease for which there are no effective treatments. To gain insights into the mechanism of renal cell carcinogenesis, a number of genome-wide expression profiling studies have been performed. Surprisingly, there is very poor agreement among these studies as to which genes are differentially regulated. To better understand this lack of agreement we profiled renal cell tumor gene expression using genome-wide microarrays (45,000 probe sets) and compare our analysis to previous microarray studies. We hybridized total RNA isolated from renal cell tumors and adjacent normal tissue to Affymetrix U133A and U133B arrays. We removed samples with technical defects and removed probesets that failed to exhibit sequence-specific hybridization in any of the samples. We detected differential gene expression in the resulting dataset with parametric methods and identified keywords that are overrepresented in the differentially expressed genes with the Fisher-exact test. We identify 1,234 genes that are more than three-fold changed in renal tumors by t-test, 800 of which have not been previously reported to be altered in renal cell tumors. Of the only 37 genes that have been identified as being differentially expressed in three or more of five previous microarray studies of renal tumor gene expression, our analysis finds 33 of these genes (89%). A key to the sensitivity and power of our analysis is filtering out defective samples and genes that are not reliably detected. The widespread use of sample-wise voting schemes for detecting differential expression that do not control for false positives likely account for the poor overlap among previous studies. Among the many genes we identified using parametric methods that were not previously reported as being differentially expressed in renal cell tumors are several oncogenes and tumor suppressor genes that likely play important roles in renal cell

Single cell elemental analysis using nuclear microscopy

International Nuclear Information System (INIS)

Ren, M.Q.; Thong, P.S.P.; Kara, U.; Watt, F.

1999-01-01

The use of Particle Induced X-ray Emission (PIXE), Rutherford Backscattering Spectrometry (RBS) and Scanning Transmission Ion Microscopy (STIM) to provide quantitative elemental analysis of single cells is an area which has high potential, particularly when the trace elements such as Ca, Fe, Zn and Cu can be monitored. We describe the methodology of sample preparation for two cell types, the procedures of cell imaging using STIM, and the quantitative elemental analysis of single cells using RBS and PIXE. Recent work on single cells at the Nuclear Microscopy Research Centre,National University of Singapore has centred around two research areas: (a) Apoptosis (programmed cell death), which has been recently implicated in a wide range of pathological conditions such as cancer, Parkinson's disease etc, and (b) Malaria (infection of red blood cells by the malaria parasite). Firstly we present results on the elemental analysis of human Chang liver cells (ATTCC CCL 13) where vanadium ions were used to trigger apoptosis, and demonstrate that nuclear microscopy has the capability of monitoring vanadium loading within individual cells. Secondly we present the results of elemental changes taking place in individual mouse red blood cells which have been infected with the malaria parasite and treated with the anti-malaria drug Qinghaosu (QHS)

BASIC TECHNICAL SKILLS (THROWS IN 17-19-YEAR-OLD JUDOKAS

Directory of Open Access Journals (Sweden)

Wladyslaw Jagiello

2014-12-01

Full Text Available Purpose: The purpose of the research was to determine basic technical skills (throws in 17-19-year-old judokas and the level of their performance. Material: The study involved 30 judo athletes (aged 17-19. Results: To determine the athletes’ basic technical skills (throws, an analysis of source materials and a diagnostic survey were used. To determine the level of technical skills, the method of expert assessment was applied. Statistical software package Statistica 8 was used in the statistical analysis. In the coaches’ opinion, 17-19-year-old judokas have a specific, characteristic of this age group, set of basic technical skills (throws aptly defining their technical preparation. Conclusions: The tested group of judokas exhibited the highest level of demonstrating throws of the koshi-waza (hip group, and the lowest one of the ashi-waza (foot group.

Thermoviscous analysis of open photoacoustic cells

Science.gov (United States)

Mannoor, Madhusoodanan; Kang, Sangmo

2017-11-01

Open photoacoustic cells, apart from the conventional spectroscopic applications, are increasingly useful in bio medical applications such as in vivo blood sugar measurement. Maximising the acoustic pressure amplitude and the quality factor are major design considerations associated with open cells.Conventionaly, resonant photoacoustic cells are analyzed by either transmission line analogy or Eigen mode expansion method. In this study, we conducted a more comprehensive thermo viscous analysis of open photoacoustic cells. A Helmholtz cell and a T-shaped cell, which are acoustically different, are considered for analysis. Effect of geometrical dimensions on the acoustic pressure, quality factor and the intrusion of noise are analyzed and compared between these cells. Specific attention is given to the sizing of the opening and fixtures on it to minimize the radiational losses and the intrusion of noise. Our results are useful for proper selection of the type of open photoacoustic cells for in vivo blood sugar measurement and the optimization of geometric variables of such cells. This research was supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT and future planning (2017R1A2B4005006).

Solid Waste Program technical baseline description

Energy Technology Data Exchange (ETDEWEB)

Carlson, A.B.

1994-07-01

The system engineering approach has been taken to describe the technical baseline under which the Solid Waste Program is currently operating. The document contains a mission analysis, function analysis, system definition, documentation requirements, facility and project bases, and uncertainties facing the program.

Ranking factors of an investment in cogeneration: sensitivity analysis ranking the technical and economical factors

International Nuclear Information System (INIS)

Sundberg, Gunnel

2001-01-01

A deregulation of the electricity market in Europe will result in increased competition among the power-producing companies. They will therefore carefully estimate the financial risk in an investment in new power-producing capability. One part of the risk assessment is to perform a sensitivity analysis. This paper presents a sensitivity analysis using factorial design, resulting in an assessment of the most important technical and economical factors affecting an investment in gas turbine combined cycle and a steam cycle fired by wood chips. The study is performed using a simulation model that optimises the operation of existing power plants and potential new investments to fulfil the desired heat demand. The local utility system analysed is a Swedish district heating system with 655 GWh y -1 heat demand. The conclusion is that to understand which of the technical and economical factors affect the investment, it is not sufficient to investigate the parameters of the studied plant, but also the parameters related to the competing plants. Both the individual effects of the factors and the effect of their interaction should be investigated. For the energy system studied the price of natural gas, price of wood chips and investment cost have the major influence on the profitability of the investment. (Author)

A new technical approach to quantify cell-cell adhesion forces by AFM

International Nuclear Information System (INIS)

Puech, Pierre-Henri; Poole, Kate; Knebel, Detlef; Muller, Daniel J.

2006-01-01

Cell-cell adhesion is a complex process that is involved in the tethering of cells, cell-cell communication, tissue formation, cell migration and the development and metastasis of tumors. Given the heterogeneous and complex nature of cell surfaces it has previously proved difficult to characterize individual cell-cell adhesion events. Force spectroscopy, using an atomic force microscope, is capable of resolving such individual cell-cell binding events, but has previously been limited in its application due to insufficient effective pulling distances. Extended pulling range is critical in studying cell-cell interactions due to the potential for large cell deformations. Here we describe an approach to such experiments, where the sample stage can be moved 100 μm in the z-direction, by closed loop, linearized piezo elements. Such an approach enables an increase in pulling distance sufficient for the observation of long-distance cell-unbinding events without reducing the imaging capabilities of the atomic force microscope. The atomic force microscope head and the piezo-driven sample stage are installed on an inverted optical microscope fitted with a piezo-driven objective, to allow the monitoring of cell morphology by conventional light microscopy, concomitant with force spectroscopy measurements. We have used the example of the WM115 melanoma cell line binding to human umbilical vein endothelial cells to demonstrate the capabilities of this system and the necessity for such an extended pulling range when quantifying cell-cell adhesion events

A prescribed wake rotor inflow and flow field prediction analysis, user's manual and technical approach

Science.gov (United States)

Egolf, T. A.; Landgrebe, A. J.

1982-01-01

A user's manual is provided which includes the technical approach for the Prescribed Wake Rotor Inflow and Flow Field Prediction Analysis. The analysis is used to provide the rotor wake induced velocities at the rotor blades for use in blade airloads and response analyses and to provide induced velocities at arbitrary field points such as at a tail surface. This analysis calculates the distribution of rotor wake induced velocities based on a prescribed wake model. Section operating conditions are prescribed from blade motion and controls determined by a separate blade response analysis. The analysis represents each blade by a segmented lifting line, and the rotor wake by discrete segmented trailing vortex filaments. Blade loading and circulation distributions are calculated based on blade element strip theory including the local induced velocity predicted by the numerical integration of the Biot-Savart Law applied to the vortex wake model.

A framework for establishing the technical efficiency of Electricity Distribution Counties (EDCs) using Data Envelopment Analysis

International Nuclear Information System (INIS)

Mullarkey, Shane; Caulfield, Brian; McCormack, Sarah; Basu, Biswajit

2015-01-01

Highlights: • Six models are employed to establish the technical efficiency of Electricity Distribution Counties. • A diagnostic parameter is incorporated to account for differences across Electricity Distribution Counties. • The amalgamation of Electricity Distribution Counties leads to improved efficiency in the production of energy. - Abstract: European Energy market liberalization has entailed the restructuring of electricity power markets through the unbundling of electricity generation, transmission and distribution, supply activities and introducing competition into electricity generation. Under these new electricity market regimes, it is important to have an evaluation tool that is capable of examining the impacts of these market changes. The adoption of Data Envelopment Analysis as a form of benchmarking for electricity distribution regulation is one method to conduct this analysis. This paper applies a Data Envelopment Analysis framework to the electricity distribution network in Ireland to explore the merits of using this approach, to determine the technical efficiency and the potential scope for efficiency improvements through reorganizing and the amalgamation of the distribution network in Ireland. The results presented show that overall grid efficiency is improved through this restructuring. A diagnostic parameter is defined and pursued to account for aberrations across Electricity Distribution Counties as opposed to the traditionally employed environmental variables. The adoption of this diagnostic parameter leads to a more intuitive understanding of Electricity Distribution Counties

Untangling cell tracks: Quantifying cell migration by time lapse image data analysis.

Science.gov (United States)

Svensson, Carl-Magnus; Medyukhina, Anna; Belyaev, Ivan; Al-Zaben, Naim; Figge, Marc Thilo

2018-03-01

Automated microscopy has given researchers access to great amounts of live cell imaging data from in vitro and in vivo experiments. Much focus has been put on extracting cell tracks from such data using a plethora of segmentation and tracking algorithms, but further analysis is normally required to draw biologically relevant conclusions. Such relevant conclusions may be whether the migration is directed or not, whether the population has homogeneous or heterogeneous migration patterns. This review focuses on the analysis of cell migration data that are extracted from time lapse images. We discuss a range of measures and models used to analyze cell tracks independent of the biological system or the way the tracks were obtained. For single-cell migration, we focus on measures and models giving examples of biological systems where they have been applied, for example, migration of bacteria, fibroblasts, and immune cells. For collective migration, we describe the model systems wound healing, neural crest migration, and Drosophila gastrulation and discuss methods for cell migration within these systems. We also discuss the role of the extracellular matrix and subsequent differences between track analysis in vitro and in vivo. Besides methods and measures, we are putting special focus on the need for openly available data and code, as well as a lack of common vocabulary in cell track analysis. © 2017 International Society for Advancement of Cytometry. © 2017 International Society for Advancement of Cytometry.

A "Virtual Fieldtrip": Service Learning in Distance Education Technical Writing Courses

Science.gov (United States)

Soria, Krista M.; Weiner, Brad

2013-01-01

This mixed-methods experimental study examined the effect of service learning in a distance education technical writing course. Quantitative analysis of data found evidence for a positive relationship between participation in service learning and technical writing learning outcomes. Additionally, qualitative analysis suggests that service learning…

ITER co-ordinated technical activities

International Nuclear Information System (INIS)

2001-01-01

As agreed upon between the ITER Engineering Design Activities (EDA) Parties 'Co-ordinated Technical Activities' (CTA) means technical activities which are deemed necessary to maintain the integrity of the international project, so as to prepare for the ITER joint implementation. The scope of these activities includes design adaptation to the specific site conditions, safety analysis and licensing preparation that are based on specific site offers, evaluation of cost and construction schedule, preparation of procurement documents and other issues raised by the Parties collectively, whilst assuring the coherence of the ITER project including design control

INDOT Technical Training Plan : [Technical Summary

Science.gov (United States)

2012-01-01

A wide range of job classifications, increasing technical : performance expectations, licensing and certification requirements, : budget restrictions and frequent department : reorganization has made technical training of employees : more difficult, ...

Technical assessment of electric heat boosters in low-temperature district heating based on combined heat and power analysis

DEFF Research Database (Denmark)

Cai, Hanmin; You, Shi; Wang, Jiawei

2018-01-01

This paper provides a technical assessment of electric heat boosters (EHBs) in low-energy districts. The analysis is based on a hypothetical district with 23 terraced single-family houses supplied by both a lowtemperature district heating (LTDH) network and a low-voltage network (LVN). Two case...

Technical Aspect for Operating Portable Prompt Gamma Neutron Activation Analysis (PGNAA) on Terengganu Inscribed Stone

International Nuclear Information System (INIS)

Rasif Mohd Zain; Hearie Hassan; Roslan Yahya

2015-01-01

Prompt Gamma Neutron Activation analysis (PGNAA) is a type of neutron activation analysis which can determined element with nearly no gamma ray decay after being irradiated by neutron sourced. Thus, element that cannot be determined by the conventional NAA for example H, B, N, Si and Cd, can be determine by PGNAA. This paper focuses on the technical working procedure for operating portable PGNAA in field work. The device is designed as a portable non-destructive investigation tool applying an isotopic neutron source (Cf-252) and a gamma-ray spectroscopy system for in-situ investigation. The studied have been carried out on Terengganu inscribed stone at Terengganu State Museum. (author)

Going single but not solo with podocytes: potentials, limitations, and pitfalls of single-cell analysis.

Science.gov (United States)

Schiffer, Mario

2017-11-01

Single-cell RNA-sequence (RNA-seq) is a widely used tool to study biological questions in single cells. The discussed study identified 92 genes being predominantly expressed in podocytes based on a 5-fold higher expression compared with endothelial and mesangial cells. In addition to technical pitfalls, the question that is discussed in this commentary is whether results of a single-cell RNAseq study are able to deliver expression data that truly characterize a podocyte. Copyright © 2017 International Society of Nephrology. Published by Elsevier Inc. All rights reserved.

[NASA/DOD Aerospace Knowledge Diffusion Research Project. Report 2:] Technical communications in aeronautics: Results of an exploratory study. An analysis of managers' and nonmanagers' responses

Science.gov (United States)

Pinelli, Thomas E.; Glassman, Myron; Barclay, Rebecca O.; Oliu, Walter E.

1989-01-01

Data collected from an exploratory study concerned with the technical communications practices of aerospace engineers and scientists were analyzed to test the primary assumption that aerospace managers and nonmanagers have different technical communications practices. Five assumptions were established for the analysis. Aerospace managers and nonmanagers were found to have different technical communications practices for three of the five assumptions tested. Although aerospace managers and nonmanagers were found to have different technical communications practices, the evidence was neither conclusive nor compelling that the presumption of difference in practices could be attributed to the duties performed by aerospace managers and nonmanagers.

H2@Scale: Technical and Economic Potential of Hydrogen as an Energy Intermediate

Energy Technology Data Exchange (ETDEWEB)

Ruth, Mark F [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Jadun, Paige [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Pivovar, Bryan S [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

2017-11-09

The H2@Scale concept is focused on developing hydrogen as an energy carrier and using hydrogen's properties to improve the national energy system. Specifically hydrogen has the abilities to (1) supply a clean energy source for industry and transportation and (2) increase the profitability of variable renewable electricity generators such as wind turbines and solar photovoltaic (PV) farms by providing value for otherwise potentially-curtailed electricity. Thus the concept also has the potential to reduce oil dependency by providing a low-carbon fuel for fuel cell electric vehicles (FCEVs), reduce emissions of carbon dioxide and pollutants such as NOx, and support domestic energy production, manufacturing, and U.S. economic competitiveness. The analysis reported here focuses on the potential market size and value proposition for the H2@Scale concept. It involves three analysis phases: 1. Initial phase estimating the technical potential for hydrogen markets and the resources required to meet them; 2. National-scale analysis of the economic potential for hydrogen and the interactions between willingness to pay by hydrogen users and the cost to produce hydrogen from various sources; and 3. In-depth analysis of spatial and economic issues impacting hydrogen production and utilization and the markets. Preliminary analysis of the technical potential indicates that the technical potential for hydrogen use is approximately 60 million metric tons (MMT) annually for light duty FCEVs, heavy duty vehicles, ammonia production, oil refining, biofuel hydrotreating, metals refining, and injection into the natural gas system. The technical potential of utility-scale PV and wind generation independently are much greater than that necessary to produce 60 MMT / year hydrogen. Uranium, natural gas, and coal reserves are each sufficient to produce 60 MMT / year hydrogen in addition to their current uses for decades to centuries. National estimates of the economic potential of

Multiscale Analysis of Foreign Exchange Order Flows and Technical Trading Profitability

OpenAIRE

Nikola Gradojevic; Camillo Lento

2012-01-01

This paper investigates the multiscale (frequency-dependent) relationship between technical trading profitability and feedback trading effects in the Canada/U.S. dollar foreign exchange market. The results suggest weak evidence that technical trading activities of financial and non-financial customers drive frequent violations of the FX market microstructure assumption that exchange rate movements are driven by order flow. After controlling for transaction costs, we find that the contribution...

Lessons from single-cell transcriptome analysis of oxygen-sensing cells.

Science.gov (United States)

Zhou, Ting; Matsunami, Hiroaki

2018-05-01

The advent of single-cell RNA-sequencing (RNA-Seq) technology has enabled transcriptome profiling of individual cells. Comprehensive gene expression analysis at the single-cell level has proven to be effective in characterizing the most fundamental aspects of cellular function and identity. This unbiased approach is revolutionary for small and/or heterogeneous tissues like oxygen-sensing cells in identifying key molecules. Here, we review the major methods of current single-cell RNA-Seq technology. We discuss how this technology has advanced the understanding of oxygen-sensing glomus cells in the carotid body and helped uncover novel oxygen-sensing cells and mechanisms in the mice olfactory system. We conclude by providing our perspective on future single-cell RNA-Seq research directed at oxygen-sensing cells.

Development of knowledge models by linguistic analysis of lexical relationships in technical documents

International Nuclear Information System (INIS)

Seguela, Patrick

2001-01-01

This research thesis addresses the problem of knowledge acquisition and structuring from technical texts, and the use of this knowledge in the development of models. The author presents the Cameleon method which aims at extracting binary lexical relationships from technical texts by identifying linguistic markers. The relevance of this method is assessed in the case of four different corpuses: a written technical corpus, an oral technical corpus, a corpus of texts of instructions, and a corpus of academic texts. The author reports the development of a model of representation of knowledge of a specific field by using lexical relationships. The method is then applied to develop a model used in document search within a knowledge management system [fr

Conjoint utility analysis of technical maturity and project progress of construction project

Directory of Open Access Journals (Sweden)

Ma Wei

2016-01-01

Full Text Available In this paper, taking construction project as the research object, the relationship between the project maturity index calculated by the construction project technical risks with different fine degree and the project progress index is studied, and the equilibrium relationship between the Party A’s utility curve and the Party B’s cost curve of using project maturity index and project progress index as the research variables is analyzed. The results show that, when the construction project technical risk division is more precise, the conjoint utility of the project's technical maturity index and the project progress is higher, and the project’s Party A and Party B two sides are closer to the optimal equilibrium. This shows that the construction project technical risk must be finely divided, and managed and controlled respectively, which will help to improve the conjoint utility of the project Party A and Party B two sides.

AN ANALYSIS OF TECHNICAL SECURITY CONTROL REQUIREMENTS FOR DIGITAL I&C SYSTEMS IN NUCLEAR POWER PLANTS

Directory of Open Access Journals (Sweden)

JAE-GU SONG

2013-10-01

Full Text Available Instrumentation and control systems in nuclear power plants have been digitalized for the purpose of maintenance and precise operation. This digitalization, however, brings out issues related to cyber security. In the most recent past, international standard organizations, regulatory institutes, and research institutes have performed a number of studies addressing these systems cyber security. In order to provide information helpful to the system designers in their application of cyber security for the systems, this paper presents methods and considerations to define attack vectors in a target system, to review and select the requirements in the Regulatory Guide 5.71, and to integrate the results to identify applicable technical security control requirements. In this study, attack vectors are analyzed through the vulnerability analyses and penetration tests with a simplified safety system, and the elements of critical digital assets acting as attack vectors are identified. Among the security control requirements listed in Appendices B and C to Regulatory Guide 5.71, those that should be implemented into the systems are selected and classified in groups of technical security control requirements using the results of the attack vector analysis. For the attack vector elements of critical digital assets, all the technical security control requirements are evaluated to determine whether they are applicable and effective, and considerations in this evaluation are also discussed. The technical security control requirements in three important categories of access control, monitoring and logging, and encryption are derived and grouped according to the elements of attack vectors as results for the sample safety system.

Technical Efficiency Performance of Conventional Banks

OpenAIRE

Endri, Endri

2012-01-01

This study aims to measure the performance of the technical efficiency of the conventional commercial banks during the period 2008-2009 by using non-parametric method of Data Envelopment Analysis (DEA). Test results showed that the total of all conventional commercial banks during the period 2008-2009 has not shown that optimal performance in which the level of technical efficiency is still below 100 percent. Appalling conditions, the efficiency of national banks experienced a decline of 73.5...

Assessing the technical efficiency of health posts in rural Guatemala: a data envelopment analysis.

Science.gov (United States)

Hernández, Alison R; San Sebastián, Miguel

2014-01-01

Strengthening health service delivery to the rural poor is an important means of redressing inequities. Meso-level managers can help enhance efficiency in the utilization of existing resources through the application of practical tools to analyze routinely collected data reflecting inputs and outputs. This study aimed to assess the efficiency and change in productivity of health posts over two years in a rural department of Guatemala. Data envelopment analysis was used to measure health posts' technical efficiency and productivity change for 2008 and 2009. Input/output data were collected from the regional health office of Alta Verapaz for 34 health posts from the 19 districts comprising the health region. Technical efficiency varied widely across health posts, with mean scores of 0.78 (SD=0.24) and 0.75 (SD=0.21) in 2008 and 2009, respectively. Overall, productivity increased by 4%, though 47% of health posts experienced a decline in productivity. Results were combined on a bivariate plot to identify health posts at the high and low extremes of efficiency, which should be followed up to determine how and why their production processes are operating differently. Assessing efficiency using the data that are available at the meso-level can serve as a first step in strengthening performance. Further work is required to support managers in the routine application of efficiency analysis and putting the results to use in guiding efforts to improve service delivery and increase utilization.

Technical Efficiency of Potato and Dairy Farming in Mountainous Kazbegi District, Georgia

OpenAIRE

Shavgulidze, R.; Bedoshvili, D.; Aurbacher, J.

2017-01-01

The study employs a stochastic frontier analysis to assess technical efficiency of potato and cheese production and determine socio-economic factors that influence farmers' technical efficiency levels in mountainous Kazbegi district of Georgia. The study found improved feeding to be inversely related with technical inefficiency in cheese production. In potato production, the analysis revealed implementation of the plant protection measures and use of quality seeds to be significant aspects th...

Structural analysis of cell wall polysaccharides using PACE

Energy Technology Data Exchange (ETDEWEB)

Mortimer, Jennifer C. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States). Joint BioEnergy Institute

2017-01-01

The plant cell wall is composed of many complex polysaccharides. The composition and structure of the polysaccharides affect various cell properties including cell shape, cell function and cell adhesion. Many techniques to characterize polysaccharide structure are complicated, requiring expensive equipment and specialized operators e.g. NMR, MALDI-MS. PACE (Polysaccharide Analysis using Carbohydrate gel Electrophoresis) uses a simple, rapid technique to analyze polysaccharide quantity and structure (Goubet et al. 2002). Whilst the method here describes xylan analysis, it can be applied (by use of the appropriate glycosyl hydrolase) to any cell wall polysaccharide.

Research on technical trading and market efficiency : a trader's perspective

OpenAIRE

Vico-Ivanina, Julianna V.

2012-01-01

Research on the predictive power of technical analysis is a matter of controversy. The objective of this thesis is to look at the empirical research done on technical trading and see how the results can be used from a trader’s perspective. Some results provide strong support for the technical trading and propose useful trading strategies. However, there are some limitations regarding transaction costs, risk adjustment, and statistical tests. Technical research has developed new methodology ap...

FLAMMABLE GAS TECHNICAL BASIS DOCUMENT

Energy Technology Data Exchange (ETDEWEB)

KRIPPS, L.J.

2005-03-03

This document describes the qualitative evaluation of frequency and consequences for DST and SST representative flammable gas accidents and associated hazardous conditions without controls. The evaluation indicated that safety-significant structures, systems and components (SSCs) and/or technical safety requirements (TSRs) were required to prevent or mitigate flammable gas accidents. Discussion on the resulting control decisions is included. This technical basis document was developed to support WP-13033, Tank Farms Documented Safety Analysis (DSA), and describes the risk binning process for the flammable gas representative accidents and associated represented hazardous conditions. The purpose of the risk binning process is to determine the need for safety-significant structures, systems, and components (SSC) and technical safety requirement (TSR)-level controls for a given representative accident or represented hazardous condition based on an evaluation of the event frequency and consequence.

Liver CT image processing: a short introduction of the technical elements.

Science.gov (United States)

Masutani, Y; Uozumi, K; Akahane, Masaaki; Ohtomo, Kuni

2006-05-01

In this paper, we describe the technical aspects of image analysis for liver diagnosis and treatment, including the state-of-the-art of liver image analysis and its applications. After discussion on modalities for liver image analysis, various technical elements for liver image analysis such as registration, segmentation, modeling, and computer-assisted detection are covered with examples performed with clinical data sets. Perspective in the imaging technologies is also reviewed and discussed.

Liver CT image processing: A short introduction of the technical elements

International Nuclear Information System (INIS)

Masutani, Y.; Uozumi, K.; Akahane, Masaaki; Ohtomo, Kuni

2006-01-01

In this paper, we describe the technical aspects of image analysis for liver diagnosis and treatment, including the state-of-the-art of liver image analysis and its applications. After discussion on modalities for liver image analysis, various technical elements for liver image analysis such as registration, segmentation, modeling, and computer-assisted detection are covered with examples performed with clinical data sets. Perspective in the imaging technologies is also reviewed and discussed

Technical Versus Public Spheres: A Feminist Analysis of Women's Rhetoric in the Twilight Sleep Debates of 1914-1916.

Science.gov (United States)

Johnson, Bethany; Quinlan, Margaret M

2015-01-01

Twilight Sleep (TS) describes the delivery, via an injection, of an amnestic drug cocktail to a parturient woman throughout labor. In order to understand the development of modern-day rhetoric surrounding childbirth methods and procedures, this article explores the debate over TS between the public and technical sphere in New York City between 1914 and 1916 and examines the ways in which this debate altered obstetric health care for middle- and upper-class White women. The public response to this campaign posed a direct challenge to male obstetricians in New York City, many of whom were ill-equipped, both literally and figuratively, to use this procedure. Using a feminist rhetorical criticism, we examined the pro-TS rhetoric of women writers in New York City, the methods they borrowed from the women's movement, and the ensuing dialogue between the public and technical spheres. For this study, we analyzed journal and newspaper articles, a pamphlet, a collection of pro-TS organizational documents, letters to the editor, and books published about TS and the history of birth. Lastly, we analyzed theoretical notions of childbirth in women's health and communication studies. After examining the TS debate, we found that birth practices for middle- and upper-class women in New York City shifted and the obstetric community gained ascendancy over female midwifery. We also found that in certain instances, the rhetoric of pro-TS activists was more technically accurate than the rhetoric of some physicians. Hence the TS debate emerged from an argument over the right to use technical language in the technical and/or the public sphere. Conclusions and implications offered by this historical, feminist analysis question our current understanding of women's health and birthing practices, doctor-patient communication, and patient empowerment and access to technical knowledge.

Technical basis for the ITER final design report, cost review and safety analysis (FDR)

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-12-01

The ITER final design report, cost review and safety analysis (FDR) is the 4th major milestone, representing the progress made in the ITER Engineering Design Activities. With the approval of the Detailed Design Report (DDR), the design work was concentrated on the requirements of operation, with only relatively minor changes to design concepts of major components. The FDR is the culmination of almost 6 years collaborative design and supporting technical work by the ITER Joint Central Team and Home Teams under the terms of the ITER EDA Agreement. Refs, figs, tabs

Technical basis for the ITER final design report, cost review and safety analysis (FDR)

International Nuclear Information System (INIS)

1998-01-01

The ITER final design report, cost review and safety analysis (FDR) is the 4th major milestone, representing the progress made in the ITER Engineering Design Activities. With the approval of the Detailed Design Report (DDR), the design work was concentrated on the requirements of operation, with only relatively minor changes to design concepts of major components. The FDR is the culmination of almost 6 years collaborative design and supporting technical work by the ITER Joint Central Team and Home Teams under the terms of the ITER EDA Agreement

Second NASA Technical Interchange Meeting (TIM): Advanced Technology Lifecycle Analysis System (ATLAS) Technology Tool Box (TTB)

Science.gov (United States)

ONeil, D. A.; Mankins, J. C.; Christensen, C. B.; Gresham, E. C.

2005-01-01

The Advanced Technology Lifecycle Analysis System (ATLAS), a spreadsheet analysis tool suite, applies parametric equations for sizing and lifecycle cost estimation. Performance, operation, and programmatic data used by the equations come from a Technology Tool Box (TTB) database. In this second TTB Technical Interchange Meeting (TIM), technologists, system model developers, and architecture analysts discussed methods for modeling technology decisions in spreadsheet models, identified specific technology parameters, and defined detailed development requirements. This Conference Publication captures the consensus of the discussions and provides narrative explanations of the tool suite, the database, and applications of ATLAS within NASA s changing environment.

Global Spent Fuel Logistics Systems Study (GSFLS). Volume 3. GSFLS technical and financial analysis. Interim report

International Nuclear Information System (INIS)

1978-01-01

This report is a part of the interim report documentation for the Global Spent Fuel Logistics System (GSFLS) study. The technical and financial considerations underlying a global spent fuel logistics systems have been studied and are reported herein. The Pacific Basin is used as a model throughout this report; however the stated methodology and, in many cases, considerations and conclusions are applicable to other global regions. Spent fuel discharge profiles for Pacific Basin Countries were used to determine the technical systems requirements for alternative concepts. Functional analyses and flows were generated to define both system design requirements and logistics parameters. A technology review was made to ascertain the state-of-the-art of relevant GSFLS technical systems. Modular GSFLS facility designs were developed using the information generated from the functional analysis and technology review. The modular facility designs were used as a basis for siting and cost estimates for various GSFLS alternatives. Various GSFLS concepts were analyzed from a financial and economic perspective in order to provide total concepts costs and ascertain financial and economic sensitivities to key GSFLS variations. Results of the study include quantification of GSFLS facility and hardware requirements; drawings of relevant GSFLS facility designs; system cost estimates; financial reports - including user service charges; and comparative analyses of various GSFLS alternatives

Global Spent Fuel Logistics Systems Study (GSFLS). Volume 3A. GSFLS technical analysis (appendix). Interim report

International Nuclear Information System (INIS)

1978-01-01

This report is a part of the interim report documentation for the Global Spent Fuel Logistics System (GSFLS) study. The technical and financial considerations underlying a global spent fuel logistics systems have been studied and are reported. The Pacific Basin is used as a model throughout this report; however the stated methodology and, in many cases, considerations and conclusions are applicable to other global regions. Spent fuel discharge profiles for Pacific Basin Countries were used to determine the technical systems requirements for alternative concepts. Functional analyses and flows were generated to define both system design requirements and logistics parameters. A technology review was made to ascertain the state-of-the-art of relevant GSFLS technical systems. Modular GSFLS facility designs were developed using the information generated from the functional analysis and technology review. The modular facility designs were used as a basis for siting and cost estimates for various GSFLS alternatives. Various GSFLS concepts were analyzed from a financial and economic perspective in order to provide total concepts costs and ascertain financial and economic sensitivities to key GSFLS variations. Results of the study include quantification of GSFLS facility and hardware requirements; drawings of relevant GSFLS facility designs; system cost estimates; financial reports - including user service charges; and comparative analyses of various GSFLS alternatives

Global Spent Fuel Logistics Systems Study (GSFLS). Volume 3A. GSFLS technical analysis (appendix). Interim report

Energy Technology Data Exchange (ETDEWEB)

Kriger, A.

1978-01-31

This report is a part of the interim report documentation for the Global Spent Fuel Logistics System (GSFLS) study. The technical and financial considerations underlying a global spent fuel logistics systems have been studied and are reported. The Pacific Basin is used as a model throughout this report; however the stated methodology and, in many cases, considerations and conclusions are applicable to other global regions. Spent fuel discharge profiles for Pacific Basin Countries were used to determine the technical systems requirements for alternative concepts. Functional analyses and flows were generated to define both system design requirements and logistics parameters. A technology review was made to ascertain the state-of-the-art of relevant GSFLS technical systems. Modular GSFLS facility designs were developed using the information generated from the functional analysis and technology review. The modular facility designs were used as a basis for siting and cost estimates for various GSFLS alternatives. Various GSFLS concepts were analyzed from a financial and economic perspective in order to provide total concepts costs and ascertain financial and economic sensitivities to key GSFLS variations. Results of the study include quantification of GSFLS facility and hardware requirements; drawings of relevant GSFLS facility designs; system cost estimates; financial reports - including user service charges; and comparative analyses of various GSFLS alternatives.

CT-guided Bipolar and Multipolar Radiofrequency Ablation (RF Ablation) of Renal Cell Carcinoma: Specific Technical Aspects and Clinical Results

Energy Technology Data Exchange (ETDEWEB)

Sommer, C. M., E-mail: christof.sommer@med.uni-heidelberg.de [University Hospital Heidelberg, INF 110, Department of Diagnostic and Interventional Radiology (Germany); Lemm, G.; Hohenstein, E. [Minimally Invasive Therapies and Nuclear Medicine, SLK Kliniken Heilbronn GmbH, Clinic for Radiology (Germany); Bellemann, N.; Stampfl, U. [University Hospital Heidelberg, INF 110, Department of Diagnostic and Interventional Radiology (Germany); Goezen, A. S.; Rassweiler, J. [Clinic for Urology, SLK Kliniken Heilbronn GmbH (Germany); Kauczor, H. U.; Radeleff, B. A. [University Hospital Heidelberg, INF 110, Department of Diagnostic and Interventional Radiology (Germany); Pereira, P. L. [Minimally Invasive Therapies and Nuclear Medicine, SLK Kliniken Heilbronn GmbH, Clinic for Radiology (Germany)

2013-06-15

Purpose. This study was designed to evaluate the clinical efficacy of CT-guided bipolar and multipolar radiofrequency ablation (RF ablation) of renal cell carcinoma (RCC) and to analyze specific technical aspects between both technologies. Methods. We included 22 consecutive patients (3 women; age 74.2 {+-} 8.6 years) after 28 CT-guided bipolar or multipolar RF ablations of 28 RCCs (diameter 2.5 {+-} 0.8 cm). Procedures were performed with a commercially available RF system (Celon AG Olympus, Berlin, Germany). Technical aspects of RF ablation procedures (ablation mode [bipolar or multipolar], number of applicators and ablation cycles, overall ablation time and deployed energy, and technical success rate) were analyzed. Clinical results (local recurrence-free survival and local tumor control rate, renal function [glomerular filtration rate (GFR)]) and complication rates were evaluated. Results. Bipolar RF ablation was performed in 12 procedures and multipolar RF ablation in 16 procedures (2 applicators in 14 procedures and 3 applicators in 2 procedures). One ablation cycle was performed in 15 procedures and two ablation cycles in 13 procedures. Overall ablation time and deployed energy were 35.0 {+-} 13.6 min and 43.7 {+-} 17.9 kJ. Technical success rate was 100 %. Major and minor complication rates were 4 and 14 %. At an imaging follow-up of 15.2 {+-} 8.8 months, local recurrence-free survival was 14.4 {+-} 8.8 months and local tumor control rate was 93 %. GFR did not deteriorate after RF ablation (50.8 {+-} 16.6 ml/min/1.73 m{sup 2} before RF ablation vs. 47.2 {+-} 11.9 ml/min/1.73 m{sup 2} after RF ablation; not significant). Conclusions. CT-guided bipolar and multipolar RF ablation of RCC has a high rate of clinical success and low complication rates. At short-term follow-up, clinical efficacy is high without deterioration of the renal function.

Technical structure of the global nanoscience and nanotechnology literature

Energy Technology Data Exchange (ETDEWEB)

Kostoff, Ronald N., E-mail: kostofr@onr.navy.mil; Koytcheff, Raymond G. [Office of Naval Research (United States); Lau, Clifford G. Y. [Institute for Defense Analyses (United States)

2007-10-15

Text mining was used to extract technical intelligence from the open source global nanotechnology and nanoscience research literature. An extensive nanotechnology/nanoscience-focused query was applied to the Science Citation Index/Social Science Citation Index (SCI/SSCI) databases. The nanotechnology/nanoscience research literature technical structure (taxonomy) was obtained using computational linguistics/document clustering and factor analysis. The infrastructure (prolific authors, key journals/institutions/countries, most cited authors/journals/documents) for each of the clusters generated by the document clustering algorithm was obtained using bibliometrics. Another novel addition was the use of phrase auto-correlation maps to show technical thrust areas based on phrase co-occurrence in Abstracts, and the use of phrase-phrase cross-correlation maps to show technical thrust areas based on phrase relations due to the sharing of common co-occurring phrases. The {approx}400 most cited nanotechnology papers since 1991 were grouped, and their characteristics generated. Whereas the main analysis provided technical thrusts of all nanotechnology papers retrieved, analysis of the most cited papers allowed their characteristics to be displayed. Finally, most cited papers from selected time periods were extracted, along with all publications from those time periods, and the institutions and countries were compared based on their representation in the most cited documents list relative to their representation in the most publications list.

Technical structure of the global nanoscience and nanotechnology literature

International Nuclear Information System (INIS)

Kostoff, Ronald N.; Koytcheff, Raymond G.; Lau, Clifford G. Y.

2007-01-01

Text mining was used to extract technical intelligence from the open source global nanotechnology and nanoscience research literature. An extensive nanotechnology/nanoscience-focused query was applied to the Science Citation Index/Social Science Citation Index (SCI/SSCI) databases. The nanotechnology/nanoscience research literature technical structure (taxonomy) was obtained using computational linguistics/document clustering and factor analysis. The infrastructure (prolific authors, key journals/institutions/countries, most cited authors/journals/documents) for each of the clusters generated by the document clustering algorithm was obtained using bibliometrics. Another novel addition was the use of phrase auto-correlation maps to show technical thrust areas based on phrase co-occurrence in Abstracts, and the use of phrase-phrase cross-correlation maps to show technical thrust areas based on phrase relations due to the sharing of common co-occurring phrases. The ∼400 most cited nanotechnology papers since 1991 were grouped, and their characteristics generated. Whereas the main analysis provided technical thrusts of all nanotechnology papers retrieved, analysis of the most cited papers allowed their characteristics to be displayed. Finally, most cited papers from selected time periods were extracted, along with all publications from those time periods, and the institutions and countries were compared based on their representation in the most cited documents list relative to their representation in the most publications list

Treatment and technical intervention time analysis of a robotic stereotactic radiotherapy system.

Science.gov (United States)

Crop, F; Lacornerie, T; Szymczak, H; Felin, A; Bailleux, C; Mirabel, X; Lartigau, E

2014-02-01

The purpose of this study is to obtain a better operational knowledge of Stereotactic Body Radiotherapy (SBRT) treatments with CyberKnife(r). An analysis of both In-room Times (IRT) and technical interventions of 5 years of treatments was performed, during which more than 1600 patients were treated for various indications, including liver (21%), lung (29%), intracranial (13%), head and neck (11%) and prostate (7%). Technical interventions were recorded along with the time of the failure, time to the intervention, and the complexity and duration of the repair. Analyses of Time Between Failures (TBF) and Service Disrupting TBF(disr) were performed. Treatment time data and variability per indication and following different system upgrades were evaluated. Large variations of IRTs were found between indications, but also large variations for each indication. The combination of the time reduction Tool (using Iris(r)) and Improved Stop Handling was of major impact to shortening of treatment times. The first implementation of the Iris collimator alone did not lead to significantly shorter IRTs for us except during prostate treatments. This was mostly due to the addition at the same time of larger rotational compensation for prostate treatments (58 instead of 1.58). Significant differences of duration between the first fraction and following fractions of a treatment, representing the necessity of defining imaging parameters and explanation to patients, were found for liver (12 min) and lung treatments using Xsight(r) Spine (5 min). Liver and lung treatments represent the longest IRT's and involve the largest variability's in IRT. The malfunction rate of the system followed a Weibull distribution with the shape and scale parameters of 0.8 and 39.7. Mean TBF(disr) was 68 work hours. 60 to 80% of the service disrupting interventions were resolved within 30-60 min, 5% required external intervention and 30% occurred in the morning. The presented results can be applied in the

Safety and man in light of the analysis of major technical accidents

International Nuclear Information System (INIS)

Carnino, A.

1990-01-01

Up to the seventies, it was not easy to admit human failure as a cause of industrial accidents. Man was considered as reliable. With the perfection of materials, technical systems and industrial processes though, man has become the weakest link in the chain of technical events. He is and stays a remarkably reliable being, with a roughly estimated average failure quota of 1:1000 manipulations. If the hypothetical risk should be kept very low, this value can become a problem. Instead of judging a mistake as a punishable crime, as the present tendency will have it, a more differentiated, systematical approach is called for. By means of an analysis of four major accidents - Chernobyl, Three Mile Island, Challenger and Bhopal - interesting parallels between the causes of such accidents can be found. Human failure, e.g. of a surgeon, is in most cases, the direct cause of an accident. A whole series of further causes, which can be assigned to different areas of influence but are usually interdependent, also play a role. While the human factor must be viewed as more or less predetermined, far reaching improvements can be made to reduce the risk of accident. Today, thanks to modern technology and new findings, it is possible to practically neutralize human error. This creates more costs and necessitates giving up short term production maximization. It also requires the willingness to give safety absolute priority. The name 'culture de surete' (safety culture) is used to describe this concept. Surprising similarities between the causes of the four mentioned major accidents were discovered. Certain circumstances, such as the time of day, played a role. The concept of a plant, resp. technical process has an essential influence, as well as company policy (importance of safety, preparation of emergency procedures, training, maintenance, company rules) and management (evaluation and realization of foreign and the company's own operation experiences and error alarms). (author) 7

Analyzing cell fate control by cytokines through continuous single cell biochemistry.

Science.gov (United States)

Rieger, Michael A; Schroeder, Timm

2009-10-01

Cytokines are important regulators of cell fates with high clinical and commercial relevance. However, despite decades of intense academic and industrial research, it proved surprisingly difficult to describe the biological functions of cytokines in a precise and comprehensive manner. The exact analysis of cytokine biology is complicated by the fact that individual cytokines control many different cell fates and activate a multitude of intracellular signaling pathways. Moreover, although activating different molecular programs, different cytokines can be redundant in their biological effects. In addition, cytokines with different biological effects can activate overlapping signaling pathways. This prospect article will outline the necessity of continuous single cell biochemistry to unravel the biological functions of molecular cytokine signaling. It focuses on potentials and limitations of recent technical developments in fluorescent time-lapse imaging and single cell tracking allowing constant long-term observation of molecules and behavior of single cells. (c) 2009 Wiley-Liss, Inc.

Probabilistic Structural Analysis Methods for select space propulsion system components (PSAM). Volume 3: Literature surveys and technical reports

Science.gov (United States)

1992-01-01

The technical effort and computer code developed during the first year are summarized. Several formulations for Probabilistic Finite Element Analysis (PFEA) are described with emphasis on the selected formulation. The strategies being implemented in the first-version computer code to perform linear, elastic PFEA is described. The results of a series of select Space Shuttle Main Engine (SSME) component surveys are presented. These results identify the critical components and provide the information necessary for probabilistic structural analysis.

CONTRIBUTING FACTORS TOWARDS DIFFICULTIES IN GENERATING IDEAS AMONG TECHNICAL STUDENTS

OpenAIRE

Yee Mei Heong

2013-01-01

Idea is a thought or collection of thoughts that are important to decision making and problem solving.  The purpose of this research was to analysis the factors contributing to difficulty in generating ideas among technical students.  A total of 375 technical students from four technical universities in Malaysia were randomly selected as samples.  A set of questionnaires was developed and used as research instrument.  The findings indicated that a total of 319 (85.1%) technical students faced...

Clinical and technical characteristics of intraoperative radiotherapy. Analysis of the ISIORT-Europe database

International Nuclear Information System (INIS)

Krengli, M.; Sedlmayer, F.

2013-01-01

Background: A joint analysis of clinical data from centres within the European section of the International Society of Intraoperative Radiation Therapy (ISIORT-Europe) was undertaken in order to define the range of intraoperative radiotherapy (IORT) techniques and indications encompassed by its member institutions. Materials and methods: In 2007, the ISIORT-Europe centres were invited to record demographic, clinical and technical data relating to their IORT procedures in a joint online database. Retrospective data entry was possible. Results: The survey encompassed 21 centres and data from 3754 IORT procedures performed between 1992 and 2011. The average annual number of patients treated per institution was 42, with three centres treating more than 100 patients per year. The most frequent tumour was breast cancer with 2395 cases (63.8 %), followed by rectal cancer (598 cases, 15.9 %), sarcoma (221 cases, 5.9 %), prostate cancer (108 cases, 2.9 %) and pancreatic cancer (80 cases, 2.1 %). Clinical details and IORT technical data from these five tumour types are reported. Conclusion: This is the first report on a large cohort of patients treated with IORT in Europe. It gives a picture of patient selection methods and treatment modalities, with emphasis on the main tumour types that are typically treated by this technique and may benefit from it. (orig.)

Agent-Based Modeling and Analysis of Socio-Technical Systems

NARCIS (Netherlands)

Sharpanskykh, O.

2011-01-01

Socio-technical systems are characterized by high structural and behavioral complexities, which impede understanding and modeling of such systems. In particular, reciprocal relations between diverse local system processes that determine global system dynamics are not well understood. In this article

Texas Hydrogen Education Final Scientific/Technical Report

Energy Technology Data Exchange (ETDEWEB)

Hitchcock, David; Bullock, Dan

2011-06-30

The Texas Hydrogen Education project builds on past interest in hydrogen and fuel cells to help create better informed leaders and stakeholders and thereby improve decision making and planning for inclusion of hydrogen and fuel cell technologies as energy alternatives in Texas. In past years in Texas, there was considerable interest and activities about hydrogen and fuel cells (2000-­2004). During that time, the Houston Advanced Research Center (HARC) created a fuel cell consortium and a fuel cell testing lab. Prior to 2008, interest and activities had declined substantially. In 2008, in cooperation with the Texas H2 Coalition and the State Energy Conservation Office, HARC conducted a planning process to create the Texas Hydrogen Roadmap. It was apparent from analysis conducted during the course of this process that while Texas has hydrogen and fuel cell advantages, there was little program and project activity as compared with other key states. Outreach and education through the provision of informational materials and organizing meetings was seen as an effective way of reaching decision makers in Texas. Previous hydrogen projects in Texas had identified the five major urban regions for program and project development. This geographic targeting approach was adopted for this project. The project successfully conducted the five proposed workshops in four of the target metropolitan areas: San Antonio, Houston, Austin, and the Dallas-­Ft. Worth area. In addition, eight outreach events were included to further inform state and local government leaders on the basics of hydrogen and fuel cell technologies. The project achieved its primary objectives of developing communication with target audiences and assembling credible and consistent outreach and education materials. The major lessons learned include: (1) DOE’s Clean Cities programs are a key conduit to target transportation audiences, (2) real-­world fuel cell applications (fuel cell buses, fuel cell fork lifts

Visualizing interdependencies in technical design

NARCIS (Netherlands)

Oosterman, B.J.; Gaalman, G.J.C.; Kuijpers, F.P.J.; Riiahuhta, A.; Pulkkinen, A.

2001-01-01

The control and understanding of complex design processes is an important issue in practice and theory. Recent research shows that documentation and analysis of technical interactions between design tasks (using Design Structure Matrices) gives a thorough understanding of the underlying complex

TECHNICAL BASIS DOCUMENT FOR NATURAL EVENT HAZARDS

International Nuclear Information System (INIS)

KRIPPS, L.J.

2006-01-01

This technical basis document was developed to support the documented safety analysis (DSA) and describes the risk binning process and the technical basis for assigning risk bins for natural event hazard (NEH)-initiated accidents. The purpose of the risk binning process is to determine the need for safety-significant structures, systems, and components (SSC) and technical safety requirement (TSR)-level controls for a given representative accident or represented hazardous conditions based on an evaluation of the frequency and consequence. Note that the risk binning process is not applied to facility workers, because all facility worker hazardous conditions are considered for safety-significant SSCs and/or TSR-level controls

The Intercultural Component in Textbooks for Teaching a Service Technical Writing Course

Science.gov (United States)

Matveeva, Natalia

2007-01-01

This research article investigates new developments in the representation of the intercultural component in textbooks for a service technical writing course. Through textual analysis, using quantitative and qualitative techniques, I report discourse analysis of 15 technical writing textbooks published during 1993-2006. The theoretical and…

Fuel Cell System for Transportation -- 2005 Cost Estimate

Energy Technology Data Exchange (ETDEWEB)

Wheeler, D.

2006-10-01

Independent review report of the methodology used by TIAX to estimate the cost of producing PEM fuel cells using 2005 cell stack technology. The U.S. Department of Energy (DOE) Hydrogen, Fuel Cells and Infrastructure Technologies Program Manager asked the National Renewable Energy Laboratory (NREL) to commission an independent review of the 2005 TIAX cost analysis for fuel cell production. The NREL Systems Integrator is responsible for conducting independent reviews of progress toward meeting the DOE Hydrogen Program (the Program) technical targets. An important technical target of the Program is the proton exchange membrane (PEM) fuel cell cost in terms of dollars per kilowatt ($/kW). The Program's Multi-Year Program Research, Development, and Demonstration Plan established $125/kW as the 2005 technical target. Over the last several years, the Program has contracted with TIAX, LLC (TIAX) to produce estimates of the high volume cost of PEM fuel cell production for transportation use. Since no manufacturer is yet producing PEM fuel cells in the quantities needed for an initial hydrogen-based transportation economy, these estimates are necessary for DOE to gauge progress toward meeting its targets. For a PEM fuel cell system configuration developed by Argonne National Laboratory, TIAX estimated the total cost to be $108/kW, based on assumptions of 500,000 units per year produced with 2005 cell stack technology, vertical integration of cell stack manufacturing, and balance-of-plant (BOP) components purchased from a supplier network. Furthermore, TIAX conducted a Monte Carlo analysis by varying ten key parameters over a wide range of values and estimated with 98% certainty that the mean PEM fuel cell system cost would be below DOE's 2005 target of $125/kW. NREL commissioned DJW TECHNOLOGY, LLC to form an Independent Review Team (the Team) of industry fuel cell experts and to evaluate the cost estimation process and the results reported by TIAX. The results of

Mapping cellular hierarchy by single-cell analysis of the cell surface repertoire.

Science.gov (United States)

Guo, Guoji; Luc, Sidinh; Marco, Eugenio; Lin, Ta-Wei; Peng, Cong; Kerenyi, Marc A; Beyaz, Semir; Kim, Woojin; Xu, Jian; Das, Partha Pratim; Neff, Tobias; Zou, Keyong; Yuan, Guo-Cheng; Orkin, Stuart H

2013-10-03

Stem cell differentiation pathways are most often studied at the population level, whereas critical decisions are executed at the level of single cells. We have established a highly multiplexed, quantitative PCR assay to profile in an unbiased manner a panel of all commonly used cell surface markers (280 genes) from individual cells. With this method, we analyzed over 1,500 single cells throughout the mouse hematopoietic system and illustrate its utility for revealing important biological insights. The comprehensive single cell data set permits mapping of the mouse hematopoietic stem cell differentiation hierarchy by computational lineage progression analysis. Further profiling of 180 intracellular regulators enabled construction of a genetic network to assign the earliest differentiation event during hematopoietic lineage specification. Analysis of acute myeloid leukemia elicited by MLL-AF9 uncovered a distinct cellular hierarchy containing two independent self-renewing lineages with different clonal activities. The strategy has broad applicability in other cellular systems. Copyright © 2013 Elsevier Inc. All rights reserved.

[NASA/DOD Aerospace Knowledge Diffusion Research Project. Report 3:] Technical communications in aeronautics: Results of an exploratory study. An analysis of profit managers' and nonprofit managers' responses

Science.gov (United States)

Pinelli, Thomas E.; Glassman, Myron; Barclay, Rebecca O.; Oliu, Walter E.

1989-01-01

Data collected from an exploratory study concerned with the technical communications practices of aerospace engineers and scientists were analyzed to test the primary assumption that profit and nonprofit managers in the aerospace community have different technical communications practices. Five assumptions were established for the analysis. Profit and nonprofit managers in the aerospace community were found to have different technical communications practices for one of the five assumptions tested. It was, therefore, concluded that profit and nonprofit managers in the aerospace community do not have different technical communications practices.

Development of galvanic high energy cells with molten salt electrolytes

Energy Technology Data Exchange (ETDEWEB)

Borger, W.; Ely, G.; Kunze, D.; Laig-Hoerstebrock, H.; Panesar, H.; Sterr, G.; Wunderlich, A.

1985-01-01

The development work during the period 1980-1983 was mainly directed towards the development of technical LiAl/FeS cells, the development of separators, tests of cells and modules, and more basic work. An important objective was the improvement of cycle life at constant specific energy. Technical cells with 140 Ah nominal capacity at the five hour rate and 100 Wh.kg/sup -1/ specific energy performed up to 400 full cycles (30 A discharge), while in 10 Ah test cells more than 2000 full cycles have been demonstrated. The improvement of cycle life of technical cells was achieved by the use of improved separators fabricated from MgO-powder and by a vacuum-tight electrical feedthrough. A design concept of a 10 cell module has been developed based upon 200 Ah cell with two positive and three negative plates. A detailed investigation of safety aspects showed that there is no specific risk related to the LiAl/molten salt/FeS system. Thermal management of a 24 kWh battery was investigated and the Ohmic heat generated in the leads seems to be the critical factor. A range of total materials cost between 60 and 130 DM/kWh has been estimated. The price of LiAl/FeS batteries will most probably also be in the range of conventional secondary batteries. The cost/benefit analysis shows a considerable potential of energy conservation by the use of light-weight high energy batteries. Compared with a expected technical life of 7 years a pay-back period between 2 and 6 years seems attractive. However, the economy of the electric vehicle is strongly influenced by the higher purchase price of an electric vehicle and the present energy level.

Flight Technical Error Analysis of the SATS Higher Volume Operations Simulation and Flight Experiments

Science.gov (United States)

Williams, Daniel M.; Consiglio, Maria C.; Murdoch, Jennifer L.; Adams, Catherine H.

2005-01-01

This paper provides an analysis of Flight Technical Error (FTE) from recent SATS experiments, called the Higher Volume Operations (HVO) Simulation and Flight experiments, which NASA conducted to determine pilot acceptability of the HVO concept for normal operating conditions. Reported are FTE results from simulation and flight experiment data indicating the SATS HVO concept is viable and acceptable to low-time instrument rated pilots when compared with today s system (baseline). Described is the comparative FTE analysis of lateral, vertical, and airspeed deviations from the baseline and SATS HVO experimental flight procedures. Based on FTE analysis, all evaluation subjects, low-time instrument-rated pilots, flew the HVO procedures safely and proficiently in comparison to today s system. In all cases, the results of the flight experiment validated the results of the simulation experiment and confirm the utility of the simulation platform for comparative Human in the Loop (HITL) studies of SATS HVO and Baseline operations.

Technical/institutional prerequisite for nuclear forensics response framework

International Nuclear Information System (INIS)

Tamai, Hiroshi; Okubo, Ayako; Kimura, Yoshiki; Kokaji, Lisa; Shinohara, Nobuo; Tomikawa, Hirofumi

2016-01-01

Nuclear Forensics capability has been developed under the international collaborations. For its effective function, technical development in analysis of seized nuclear materials as well as the institutional development in comprehensive response framework are required under individual national responsibility. In order to keep the “chain of custody” in the proper operation of sample collection at the event scene, radiological analysis at the laboratory, storage of the samples, and further inspection and trial, close cooperation and information sharing between relevant organisations are essential. IAEA issues the Implementing Guide to provide the model action plan and assists individual national development. Some countries at the advancing stage of national response framework, promote the international cooperation for the technical improvement and awareness cultivation. Examples in such national developments will be introduced and prospective technical/institutional prerequisite for nuclear forensics response framework will be studied. (author)

Modeling Technical Change in Energy System Analysis: Analyzing the Introduction of Learning-by-Doing in Bottom-up Energy Models

Energy Technology Data Exchange (ETDEWEB)

Berglund, Christer; Soederholm, Patrik [Luleaa Univ. of Technology (Sweden). Div. of Economics

2005-02-01

The main objective of this paper is to provide an overview and a critical analysis of the recent literature on incorporating induced technical change in energy systems models. Special emphasis is put on surveying recent studies aiming at integrating learning-by-doing into bottom-up energy systems models through so-called learning curves, and on analyzing the relevance of learning curve analysis for understanding the process of innovation and technology diffusion in the energy sector. The survey indicates that this model work represents a major advance in energy research, and embeds important policy implications, not the least concerning the cost and the timing of environmental policies (including carbon emission constraints). However, bottom-up energy models with endogenous learning are also limited in their characterization of technology diffusion and innovation. While they provide a detailed account of technical options - which is absent in many top-down models - they also lack important aspects of diffusion behavior that are captured in top-down representations. For instance, they fail in capturing strategic technology diffusion behavior in the energy sector, and they neglect important general equilibrium impacts (such as the opportunity cost of redirecting R and D support to the energy sector). For these reasons bottom-up and top-down models with induced technical change should not be viewed as substitutes but rather as complements.

Technical standards in the law of technical safety

International Nuclear Information System (INIS)

Marburger, P.

1985-01-01

Technical standards are of great importance for the closer definition of inexact terms of law, for instance ''generally accepted technical rules'', ''state of the art'', ''state of science and technology'' or similar normative terms, in the law of technical safety. The paper discusses with whom the authority for regulating this sector of law rests, deals with the different ways of how technical standards are used by the law (''anticipated expert opinion'', reference to such standards in law and administration) and points out demands on the procedure of standardization. (orig.) [de

Innovative and practical technical development of nuclear energy. Efforts on proposal and recruitment type technical development of nuclear energy

International Nuclear Information System (INIS)

Matsui, Kazuaki; Shioiri, Akio; Hamada, Jun; Kanagawa, Takashi; Mori, Yukihide; Kouno, Koji

2003-01-01

In technical development of nuclear energy conceiving a view on energy environment problem at the 21st Century, technical development on innovative nuclear energy system as well as next generation LWR is an important subject. Even in Japan, on the 'Long-term program for research, development and utilization of nuclear energy (LPRNE)' summarized by the Atomic Energy Commission, investigation on R and Ds of innovative reactors under cooperation of government, industrial field, and universities is required. In the Energy Generalized Engineering Institute, by receiving a subsidy from the Ministry of Economy and Industry since 2000, a proposal recruitment business on innovative and practical technical development of nuclear energy has been carried out. Here were introduced hopeful and unique five themes out of them applied to the recruitment, such as a super-critical pressure water cooling reactor (SCPR), an integrated modular LWR (IMR): technical development for practice, technical development on general purpose boiling transitional analysis method, technical development on direct extraction of U and Pu from consumed fuels based on super-DIREX reprocessing method, and material transfer forecasting in natural barriers at landfill disposal of radioactive wastes. (G.K.)

Comparison of methods applicable to evaluation of nuclear power plant technical specifications

International Nuclear Information System (INIS)

Cho, N.Z.; Bozoki, G.E.; Youngblood, R.W.

1986-01-01

This study compares three probabilistic methods based on the static fault tree analysis, time-dependent unavailability analysis, and Markov analysis, which can be used to evaluate technical specifications in nuclear power plants. They are tested on a sample problem which was devised to closely represent the important and essential characteristics that should be addressed in determination and evaluation of the technical specifications

Unraveling cell processes: interference imaging interwoven with data analysis

DEFF Research Database (Denmark)

Brazhe, Nadezda; Brazhe, Alexey; Pavlov, A N

2006-01-01

The paper presents results on the application of interference microscopy and wavelet-analysis for cell visualization and studies of cell dynamics. We demonstrate that interference imaging of erythrocytes can reveal reorganization of the cytoskeleton and inhomogenity in the distribution of hemoglo......The paper presents results on the application of interference microscopy and wavelet-analysis for cell visualization and studies of cell dynamics. We demonstrate that interference imaging of erythrocytes can reveal reorganization of the cytoskeleton and inhomogenity in the distribution...... properties differ from cell type to cell type and depend on the cellular compartment. Our results suggest that low frequency variations (0.1-0.6 Hz) result from plasma membrane processes and that higher frequency variations (20-26 Hz) are related to the movement of vesicles. Using double-wavelet analysis, we...... study the modulation of the 1 Hz rhythm in neurons and reveal its changes under depolarization and hyperpolarization of the plasma membrane. We conclude that interference microscopy combined with wavelet analysis is a useful technique for non-invasive cell studies, cell visualization, and investigation...

Technical basis for exemption from alpha surveys for personnel, material, and equipment in the 324 facility

International Nuclear Information System (INIS)

RIDDELLE, J.G.

1998-01-01

The purpose of this document is to establish the technical basis for characterizing grouted B-Cell waste for disposal at the Hanford Burial Grounds using the 3-82B shipping cask. The scope of this document includes establishing the technical basis for loading the shipping package, an HN-200 Grout Container, to ensure that: (1) the amount of material in the grout container does not exceed the 100 nCl alpha/g limit that would cause the waste to be designated as ''greater that Category 3'' (GC3) or transuranic (TRU) waste (2) the amount of heat generated by the waste in the grout container does not exceed the 60 Watt heat generation limit established in the 3-82B shipping cask Safety Analysis Report (SAR); and (3) the dose rate on the surface of the shipping cask after loading does not exceed the 200 mrem/h limit established in the cask SAR. This document establishes the technical basis for performing measurements and analyses that will ensure that none of these three limits are exceeded

Illustration of an analytical method for quantification of the safety of technical appliances

International Nuclear Information System (INIS)

Tegel, M.

1981-01-01

The safety analysis of technical products will in future be required more and more also for simple technical systems. The fault-tree analysis is a method for safety judgement used in particular in aviation and space engineering as well as in energy engineering. This analytical method can also be applied to simple technical constructions, as the article shows, using as example an acially rotatable load hook. (orig.) [de

76 FR 64083 - Reliability Technical Conference; Notice of Technical Conference

Science.gov (United States)

2011-10-17

... Technical Conference; Notice of Technical Conference Take notice that the Federal Energy Regulatory Commission will hold a Technical Conference on Tuesday, November 29, 2011, from 1 p.m. to 5 p.m. and... reliability that were identified in earlier Commission technical conferences. The conference also will discuss...

Rape oil for technical uses - a cost-benefit analysis. A cost-benefit analysis of the production and use of rape oil as fuels and lubricants and for technical purposes

International Nuclear Information System (INIS)

Kleinhanss, W.; Kerckow, B.; Schrader, H.

1992-01-01

A brief description of the methodical fundamentals of cost-benefit analyses, the quantitative analytical models and the relevant data basis is followed by a survey of existing and potential rape oil uses. Basic data for the economic evaluation of rape seed production, rape oil production and rape oil uses are compiled, and the potentials of rape oil marketing in the Federal Republic of Germany are evaluated. The results of an evaluation of the importance of rape oil to the national trade and industry are discussed considering the optimum large-scale expansion of rape oil production, the individual uses, technical concepts, and the economic significance of technical progress. The cost benefit analysis and subsequent evaluation are based on a comparative evaluation of the additional rape oil production and of the grain production which has been giving way to rape production. In accordance with the assumed world market reference conditions rape oil production and rape oil/byproduct uses compete with grain exports at world market prices. The rape oil production costs are estimated applying the marginal costing principle, i.e production costs and follow-up effects are quantified by means of a modified regionally differentiated simulation model assuming the local conditions applicable to the Federal Republic of Germany. Four scenarios for projection of EC agricultural prices, world market prices and energy prices through 2000 are made available to level the different basic economic conditions. (UA) [de

Determination of aims military-technical policy of Ukraine

Directory of Open Access Journals (Sweden)

O. F. Salnikova

2014-06-01

Full Text Available In the article the aims of military-technical policy are considered. Determination of aims (tasks of military-technical policy, its maintenance, requirements to it and directions of its further development it must come true by the analysis of different factors of external and internal environment. Among such factors: geopolitical and military-political position of Ukraine and its military doctrine; realized and operating programs of development (reformation of the soldiery forming and them technical rigging; terms of future military operations and progress of their maintenance, forms, methods and characteristic signs of battle actions trend; substantive provisions of art of war; conceptions, theories and doctrines of battle application of the soldiery forming of the different states; resources dedicated by the state on development of military-technical sphere and others like that. The fundamental chart of sequence of forming of public military-technical policy is presented in the article.

Nuclear Energy Center Site Survey, 1975. Part III. Technical considerations

International Nuclear Information System (INIS)

1976-01-01

Studies of the technical feasibility of nuclear energy centers (NECs) and the comparison between NEC technical feasibility and that of nuclear facilities on dispersed sites are reviewed. The conclusions related to technical feasibility of NEC are summarized. Technical feasibility was found to rest mainly on five major issues: heat dissipation, transmission, facility construction, radiological impact, and environmental impact. Although general conclusions can be reached in these five areas, it is recognized that they are interdependent, and detailed site-by-site analysis will be necessary. Some general conclusions on technical feasibility of NECs are presented, then detailed conclusions derived from the technical evaluation of NECs compared to dispersed site facilities are presented. The findings of this study on each of the five major feasibility issues are then discussed in sequence. The study concludes that nuclear energy centers, as defined herein, are technically feasible

Teaching Technical Writing - Towards Technical Writing

DEFF Research Database (Denmark)

Kastberg, Peter

2000-01-01

In this paper I will present key aspects of the curriculum for the university degree in technical translation that I have designed for and subsequently implemented at the German Department of the Aarhus School of Business, Denmark. My starting point will be a critical discussion of the norm that ...... of technical writing.......In this paper I will present key aspects of the curriculum for the university degree in technical translation that I have designed for and subsequently implemented at the German Department of the Aarhus School of Business, Denmark. My starting point will be a critical discussion of the norm...... that used to govern what the quality of an LSP text should be as opposed to the standpoint, which I advocate. By way of summing up, I will show how a university curriculum is designed so that - upon graduation - the technical translator could also be methodological quite well suited to take on the challenge...

Analysis of the Factors Influencing the Technical Efficiency of ...

African Journals Online (AJOL)

The study analyzed the relationship between technical efficiency of women rubber tappers in Rubber Research Institute of Nigeria, Benin City. A total of 60 women were selected through purposive and random sampling techniques and served with a structured interview schedule. Data collected were subjected to ...

Chip based electroanalytical systems for cell analysis

DEFF Research Database (Denmark)

Spegel, C.; Heiskanen, A.; Skjolding, L.H.D.

2008-01-01

' measurements of processes related to living cells, i.e., systems without lysing the cells. The focus is on chip based amperometric and impedimetric cell analysis systems where measurements utilizing solely carbon fiber microelectrodes (CFME) and other nonchip electrode formats, such as CFME for exocytosis...

Spent nuclear fuel project technical databook

Energy Technology Data Exchange (ETDEWEB)

Reilly, M.A.

1998-07-22

The Spent Nuclear Fuel (SNF) project technical databook provides project-approved summary tables of selected parameters and derived physical quantities, with nominal design and safety basis values. It contains the parameters necessary for a complete documentation basis of the SNF Project technical and safety baseline. The databook is presented in two volumes. Volume 1 presents K Basins SNF related information. Volume 2 (not yet available) will present selected sludge and water information, as it relates to the sludge and water removal projects. The values, within this databook, shall be used as the foundation for analyses, modeling, assumptions, or other input to SNF project safety analyses or design. All analysis and modeling using a parameter available in this databook are required to use and cite the appropriate associated value, and document any changes to those values (i.e., analysis assumptions, equipment conditions, etc). Characterization and analysis efforts are ongoing to validate, or update these values.

Spent nuclear fuel project technical databook

International Nuclear Information System (INIS)

Reilly, M.A.

1998-01-01

The Spent Nuclear Fuel (SNF) project technical databook provides project-approved summary tables of selected parameters and derived physical quantities, with nominal design and safety basis values. It contains the parameters necessary for a complete documentation basis of the SNF Project technical and safety baseline. The databook is presented in two volumes. Volume 1 presents K Basins SNF related information. Volume 2 (not yet available) will present selected sludge and water information, as it relates to the sludge and water removal projects. The values, within this databook, shall be used as the foundation for analyses, modeling, assumptions, or other input to SNF project safety analyses or design. All analysis and modeling using a parameter available in this databook are required to use and cite the appropriate associated value, and document any changes to those values (i.e., analysis assumptions, equipment conditions, etc). Characterization and analysis efforts are ongoing to validate, or update these values

An analysis of Technical Security Control Requirements For Digital I and C Systems in Nuclear Power Plants

International Nuclear Information System (INIS)

Song, Jaegu; Lee, Jungwoon; Park, Geeyong; Kwon, Keechoon; Lee, Dongyoung; Lee, Cheolkwon

2013-01-01

Instrumentation and control systems in nuclear power plants have been digitalized for the purpose of maintenance and precise operation. This digitalization, however, brings out issues related to cyber security. In the most recent past, international standard organizations, regulatory institutes, and research institutes have performed a number of studies addressing these systems cyber security. In order to provide information helpful to the system designers in their application of cyber security for the systems, this paper presents methods and considerations to define attack vectors in a target system, to review and select the requirements in the Regulatory Guide 5.71, and to integrate the results to identify applicable technical security control requirements. In this study, attack vectors are analyzed through the vulnerability analyses and penetration tests with a simplified safety system, and the elements of critical digital assets acting as attack vectors are identified. Among the security control requirements listed in Appendices B and C to Regulatory Guide 5.71, those that should be implemented into the systems are selected and classified in groups of technical security control requirements using the results of the attack vector analysis. For the attack vector elements of critical digital assets, all the technical security control requirements are evaluated to determine whether they are applicable and effective, and considerations in this evaluation are also discussed. The technical security control requirements in three important categories of access control, monitoring and logging, and encryption are derived and grouped according to the elements of attack vectors as results for the sample safety system

An analysis of Technical Security Control Requirements For Digital I and C Systems in Nuclear Power Plants

Energy Technology Data Exchange (ETDEWEB)

Song, Jaegu; Lee, Jungwoon; Park, Geeyong; Kwon, Keechoon; Lee, Dongyoung; Lee, Cheolkwon [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

2013-10-15

Instrumentation and control systems in nuclear power plants have been digitalized for the purpose of maintenance and precise operation. This digitalization, however, brings out issues related to cyber security. In the most recent past, international standard organizations, regulatory institutes, and research institutes have performed a number of studies addressing these systems cyber security. In order to provide information helpful to the system designers in their application of cyber security for the systems, this paper presents methods and considerations to define attack vectors in a target system, to review and select the requirements in the Regulatory Guide 5.71, and to integrate the results to identify applicable technical security control requirements. In this study, attack vectors are analyzed through the vulnerability analyses and penetration tests with a simplified safety system, and the elements of critical digital assets acting as attack vectors are identified. Among the security control requirements listed in Appendices B and C to Regulatory Guide 5.71, those that should be implemented into the systems are selected and classified in groups of technical security control requirements using the results of the attack vector analysis. For the attack vector elements of critical digital assets, all the technical security control requirements are evaluated to determine whether they are applicable and effective, and considerations in this evaluation are also discussed. The technical security control requirements in three important categories of access control, monitoring and logging, and encryption are derived and grouped according to the elements of attack vectors as results for the sample safety system.

Biomarker-Based Analysis for Contaminants in Sediments/Soil: Review of Cell-Based Assays and cDNA Arrays

National Research Council Canada - National Science Library

Inouye, Laura

2000-01-01

This technical note reviews the existing technology for cell-based biomarker assays and cDNA arrays and explores their potential as rapid, sensitive, and low-cost tools for sediment/soil toxicity screening...

The Boston Study: Analysis of a Major Metropolitan Business- and Technical-Communication Market.

Science.gov (United States)

Buchholz, William J.

1989-01-01

Presents a year-long study of the duties, skills, and knowledge required of business- and technical-communication professionals in Boston, Massachusetts. Focuses on six categories of practice: technical communication, publishing, public relations, marketing, development, and training. Suggests that in the next decade communication practitioners…

Analysis of Technical Efficiency among Swamp Rice Farmers in ...

African Journals Online (AJOL)

This study was conducted to evaluate the Technical efficiency among swamp rice farmers in Niger State, Nigeria. A multi-stage sampling technique was used to select 159 swamp rice farmers. The data collected were analysed using descriptive statistics, and the stochastic frontier production function. The results showed ...

Technical safety requirements for the Annular Core Research Reactor Facility (ACRRF)

International Nuclear Information System (INIS)

Boldt, K.R.; Morris, F.M.; Talley, D.G.; McCrory, F.M.

1998-01-01

The Technical Safety Requirements (TSR) document is prepared and issued in compliance with DOE Order 5480.22, Technical Safety Requirements. The bases for the TSR are established in the ACRRF Safety Analysis Report issued in compliance with DOE Order 5480.23, Nuclear Safety Analysis Reports. The TSR identifies the operational conditions, boundaries, and administrative controls for the safe operation of the facility

Technical problems to be solved before the solid oxide fuel cell will be commercialized

Energy Technology Data Exchange (ETDEWEB)

Bagger, C.; Hendriksen, P.V.; Mogensen, M. [Riso National Lab., Roskilde (Denmark)

1996-12-31

The problems which must be solved before SOFC-systems are competitive with todays power production technology are of both technical and economical nature. The cost of SOFC stacks at the 25 kW level of today is about 30,000 ECU/kW and it is bound to come down to about 500 ECU/kW. The allowable cost of a SOFC system is anticipated to be around 1500 ECU/kW. As part of the Danish SOFC program (DK-SOFC) a 0.5 kW stack was built and tested during the second half of 1995. Based upon the experience gained, an economic analysis has been made. The tools required to approach an economically acceptable solution are outlined below.

Endogenous induced technical change and the costs of Kyoto

International Nuclear Information System (INIS)

Buonanno, Paolo; Carraro, Carlo; Galeotti, Marzio

2003-01-01

We present a model for climate change policy analysis which accounts for the possibility that technology evolves endogenously and that technical change can be induced by environmental policy measures. Both the output production technology and the emission-output ratio depend upon a stock of knowledge, which accumulates through R and D activities. Two versions of this model are studied, one with endogenous technical change but exogenous environmental technical change and the other with both endogenous and induced technical change. A third version also captures technological spillover effects. As an application, the model is simulated allowing for trade of pollution permits as specified in the Kyoto Protocol and assessing the implications in terms of cost efficiency, economic growth and R and D efforts of the three different specifications of technical change

Technical artifacts in chromatographic analysis of Tc-99m radiopharmaceuticals

International Nuclear Information System (INIS)

Kowalsky, R.J.; Creekmore, J.R.

1982-01-01

Technical artifacts produced during chromatographic analysis of technetium radiopharmaceuticals were investigated. Such artifacts are, we found, caused by improper spotting and drying techniques; these in turn produce spuriously high impurities in Tc-99m complexes of DTPA, MDP, PPi, and GH. The ITLC-SG/acetone system produces considerable streaking of Tc-complex if the applied spot is large and not dried before development. This results in activity in the solvent front portion of the chromatographic strip indicating falsely high levels of pertechnetate impurity. Proper drying of the applied spot eliminates the artifact. The ITLC-SG/saline system yields falsely high, hydrolyzed-reduced technetium impurities if the spot is allowed to enter the solvent during development. Correct spot placement and size eliminate this problem. Strips that are allowed to dry in room air for several minutes may indicate considerable pertechnetate impurity on the chromatogram; yet this may not actually be present in the radiopharmaceutical vial. Drying spots rapidly with hot air or in a nitrogen atmosphere before development eliminates this problem

Sensitivity of Technical Efficiency Estimates to Estimation Methods: An Empirical Comparison of Parametric and Non-Parametric Approaches

OpenAIRE

de-Graft Acquah, Henry

2014-01-01

This paper highlights the sensitivity of technical efficiency estimates to estimation approaches using empirical data. Firm specific technical efficiency and mean technical efficiency are estimated using the non parametric Data Envelope Analysis (DEA) and the parametric Corrected Ordinary Least Squares (COLS) and Stochastic Frontier Analysis (SFA) approaches. Mean technical efficiency is found to be sensitive to the choice of estimation technique. Analysis of variance and Tukey’s test sugge...