WorldWideScience

Sample records for cecropia pachystachya trec

  1. Tolerância à inundação de Cecropia pachystachya Trec. (Cecropiaceae: aspectos ecofisiológicos e morfoanatômicos Flood tolerance in Cecropia pachystachya Trec. (Cecropiaceae: ecophysiological and morpho-anatomical aspects

    Directory of Open Access Journals (Sweden)

    Claudia Universal Neves Batista

    2008-03-01

    Full Text Available Visando elucidar aspectos da tolerância à hipoxia, plantas de Cecropia pachystachya foram submetidas a 30 dias de inundação. O crescimento e desenvolvimento, a condutância estomática, a fotossíntese e a morfo-anatomia foram avaliadas. A taxa de crescimento relativo (TCR da raiz e do caule foi inferior em plantas alagadas, não havendo diferenças nesta taxa para as folhas e para a planta inteira. A não variação na TCR das folhas pode ter sido em função da maior esclerofilia foliar das plantas alagadas, que apresentaram menor área. A condutância estomática e a taxa fotossintética diminuíram nas plantas submetidas ao alagamento. Foram observadas alterações morfo-anatômicas em caules e principalmente em raízes de plantas alagadas. A análise dos resultados indica que a tolerância desta espécie a períodos de inundação está relacionada à sua capacidade de manter uma satisfatória produção energética. A manutenção de um balanço energético positivo possibilita que mesmo sob estresse, com queda na taxa fotossintética, as plantas desta espécie apresentem uma considerável TCR. Portanto, C. pachystachya pode ser forte competidora em áreas sujeitas ao alagamento.To elucidate certain aspects of hypoxia tolerance in Cecropia pachystachya, plants were submitted to 30 days of flooding. Growth and development, stomatal conductance, photosynthetic rates and morpho-anatomy were studied. Root and stem relative growth rates (RGR were lower in flooded plants. There was no difference in leaf RGR and whole plant RGR. The maintenance of leaf RGR is possibly related to greater sclerophylly in flooded plants. Stomatal conductance and photosynthetic rate decreased due to flooding. Stems and roots, especially the latter, showed morpho-anatomical alterations in flooded plants. The results so far suggest that flood tolerance in C. pachystachya is related to the capacity to maintain satisfactory energy production. The maintenance of a

  2. PHOSPHATE AND INOCULATION WITH ARBUSCULAR MYCORRHIZAL FUNGI ON THE GROWTH OF Cecropia pachystachya (Trec SEEDLINGS FÓSFORO E INOCULAÇÃO COM FUNGOS MICORRÍZICOS ARBUSCULARES NO ESTABELECIMENTO DE MUDAS DE EMBAÚBA (Cecropia pachystachya Trec

    Directory of Open Access Journals (Sweden)

    Marco Aurélio Carbone Carneiro

    2007-09-01

    Full Text Available

    The objective of this study was to evaluate the effect of the inoculation with arbuscular mycorrhizal fungi (FMA in different levels of P2O5 on the growth of Cecropia pachystachya seedlings in the field. The study consisted of a 5x2 factorial with five levels of P2O5 (zero, 85, 170, 255 and 340 mg.kg-1, with and ithout inoculation with a mixture of FMA. It was used four replications, each one with twelve seedlings. The seeds were sowed in plastic tubes with capacity of 50 cm3 of substratum and stored for 120 days. After this period the seedlings were transplanted to the field, where they remained for another 150 days. Seedling diameter and height were measured at 60 and 120 days, aerial part and root dry matter, and arbuscular mycorrhizal colonization. Diameter, height, leaf area, aerial part dry matter and the number of surviving seedlings were determined after 150 days. None of the factors tested had any effect on seedling growth with one exception; inoculated plants with FMA had more root dry matter. Plants inoculated with smaller doses of P2O5 showed a larger percentage of surviving individuals and more vigorous seedlings. Results suggest that in low fertility soils of and subject to the hydric stress the C. pachystachya seedlings should be inoculated with FMA.

    KEY-WORDS: Native vegetation; mycorrhiza fungi; native species; seedling production; inoculation.

    O objetivo deste estudo foi avaliar o efeito da inoculação com fungos micorrízicos arbusculares (FMA em diferentes doses de P2O5 na formação de mudas de embaúba (Cecropia pachystachya e no seu estabelecimento em campo. O estudo constou de um experimento fatorial 5x2, sendo cinco doses de P2O5

  3. Tolerância à inundação de Cecropia pachystachya Trec. (Cecropiaceae): aspectos ecofisiológicos e morfoanatômicos

    OpenAIRE

    Batista,Claudia Universal Neves; Medri,Moacir Eurípedes; Bianchini,Edmilson; Medri,Cristiano; Pimenta,José Antonio

    2008-01-01

    Visando elucidar aspectos da tolerância à hipoxia, plantas de Cecropia pachystachya foram submetidas a 30 dias de inundação. O crescimento e desenvolvimento, a condutância estomática, a fotossíntese e a morfo-anatomia foram avaliadas. A taxa de crescimento relativo (TCR) da raiz e do caule foi inferior em plantas alagadas, não havendo diferenças nesta taxa para as folhas e para a planta inteira. A não variação na TCR das folhas pode ter sido em função da maior esclerofilia foliar das plantas ...

  4. Herança e desequilíbrio de ligação em sete locos isoenzimáticos de Cecropia pachystachya. Inheritance and linkage disequilibrium in sevem isozymes loci of Cecropia pachystachya.

    Directory of Open Access Journals (Sweden)

    Luciano Arruda RIBAS

    2004-12-01

    Full Text Available Seis sistemas enzimáticos (ACP,G6PDH, IDH, PGI, PGM e SKDH, codificandosete locos polimórficos (Acp-3, G6pdh-1, Idh-1,Pgi-2, Pgm-1, Pgm-2 e Skdh-1, foram investigadospara a herança e desequilíbrio de ligação emCecropia pachystachya Trec. A herança mendelianafoi confirmada para todos os locos avaliados.Desvios significativos da razão de segregaçãoesperada 1:1 foram detectados apenas em umaprogênies de árvore heterozigótica. O desequilíbriode ligação foi examinado para 21 pares de locosisoenzimáticos, não sendo detectados desequilíbriosentre nenhum deles e, assim, estes podem serutilizados em subseqüentes estudos do sistemade reprodução, diversidade e estrutura genética deC. pachystachya.

  5. Antidepressant-like effects of aqueous extract from Cecropia pachystachya leaves in a mouse model of chronic unpredictable stress.

    Science.gov (United States)

    Gazal, Marta; Ortmann, Caroline Flach; Martins, Fernanda Amelia; Streck, Emilio Luiz; Quevedo, João; de Campos, Angela Machado; Stefanello, Francieli M; Kaster, Manuella P; Ghisleni, Gabriele; Reginatto, Flávio Henrique; Lencina, Claiton L

    2014-09-01

    Chronic stressful stimuli influence disease susceptibility to depression, cardiovascular, metabolic and neurodegenerative disorders. The present work investigated antidepressant and antioxidant properties of the aqueous extract from Cecropia pachystachya in a mouse model of chronic unpredictable stress (CUS). Our results indicated that acute administration of the aqueous extract (AE) from C. pachystachya (200 and 400mg/kg, p.o.) produced an antidepressant-like effect in the forced swimming test (FST). The chronic treatment with C. pachystachya extract (200mg/kg, p.o., for 14 days) prevented the depressant-like effect but not the anxiogenic effect induced by CUS. In addition to the behavioral modifications, the 14 days of CUS increased lipid peroxidation in the hippocampus (HP) and prefrontal cortex (PFC), decreased total thiol content and glutathione peroxidase activity in the HP. C. pachystachya AE administration during CUS protocol was able to prevent the oxidative damage induced by stress. However, no changes were observed in the activity of the antioxidant enzymes superoxide dismutase and catalase in the above cited brain areas after the stress protocol and treatment. Our results suggest that C. pachystachya prevented both depressive behavior and oxidative damage induced by CUS, supporting its neuroprotective potential against behavioral and biochemical dysfunctions induced by chronic stress. Copyright © 2014 Elsevier Inc. All rights reserved.

  6. Cecropia pachystachya: A Species with Expressive In Vivo Topical Anti-Inflammatory and In Vitro Antioxidant Effects

    Directory of Open Access Journals (Sweden)

    Natália Ramos Pacheco

    2014-01-01

    Full Text Available Cecropia pachystachya is a species traditionally used in Brazil to treat inflammation. This work aims to evaluate the topical anti-inflammatory and antioxidant activities of the methanolic extract of C. pachystachya (CPM and to perform its chemical fingerprint by HPLC-DAD. The topical anti-inflammatory activity was evaluated using the mouse models of acute ear inflammation induced by croton oil, arachidonic acid, capsaicin, EPP, phenol, and chronic inflammation induced by multiple application of croton oil. The in vitro antioxidant effect of CPM was investigated using DPPH, reducing power, β-carotene bleaching, and TBARS assays. HPLC analysis was performed to quantify the antioxidant phenolics orientin, isoorientin, and chlorogenic acid previously identified in CPM. CPM exhibited significant anti-inflammatory effect in the acute models, in some cases comparable to the reference drugs. Histopathological analysis showed a moderate chronic skin anti-inflammatory effect with decrease in vasodilation, edema, cell infiltration, and epidermal hyperproliferation. It also showed strong in vitro antioxidant activity. The contents of orientin, isoorientin, and chlorogenic acid were 66.5 ± 1.8, 118.8 ± 0.7, and 5.4 ± 0.2 µg/mg extract, respectively. The topical anti-inflammatory activity of CPM could be based on its antioxidant properties, although other effects are probably involved, including COX inhibition and other mechanisms.

  7. Taxa e velocidade de germinação de sementes de Cecropia pachystachya Trécul (Cecropiaceae ingeridas por Artibeus lituratus (Olfers, 1818 (Chiroptera: Phyllostomidae - DOI: 10.4025/actascibiolsci.v29i4.879 Germination rate and velocity of seeds of Cecropia pachystachya Trécul (Cecropiaceae eaten by Artibeus lituratus (Olfers, 1818 (Chiroptera: Phyllostomidae - DOI: 10.4025/actascibiolsci.v29i4.879

    Directory of Open Access Journals (Sweden)

    Eliane Cristine Vicente

    2008-02-01

    Full Text Available O objetivo deste trabalho foi verificar se o morcego frugívoro Artibeus lituratus pode ser considerado indutor na germinação de sementes de Cecropia pachystachya, sendo avaliadas a taxa e a velocidade de germinação das sementes em diferentes condições. Os morcegos e os frutos foram coletados na região central de Campo Grande, Estado do Mato Grosso do Sul; o experimento foi dividido em cinco tratamentos. O primeiro contou com sementes retiradas dos frutos; o segundo, com sementes retiradas das fezes, e o terceiro dividido em três tratamentos ácidos, com concentrações de pH 1, 2 e 3. As sementes que passaram pelo sistema digestório dos animais germinaram com maior velocidade (p 0,05 quando comparada às sementes sem tratamento. O tratamento com pH igual a 3 foi estatisticamente igual ao grupo sem tratamento e ao grupo experimental, com sementes retiradas das fezes, indicando o valor aproximado da concentração dos ácidos estomacais desta espécie frugívora. Conclui-se que Artibeus lituratus pode ser considerado indutor do aumento da velocidade de germinação nas sementes desta espécie vegetal, refletindo na importância desta espécie frugívora na manutenção ecológica dos ecossistemas tropicais, principalmente em áreas de Cerrado.The objective with this study was to verify whether frugivorous bat Artibeus lituratus can be considered an efficient germination inducer for Cecropia pachystachya seeds. Bats and fruits were collected in Campo Grande (Mato Grosso do Sul State, Brazil, with the experiment being divided in five treatments: one composed by seeds taken from natural fresh fruits, another with seeds taken from the bats’ excrements, and the last one sub-divided in three sub-groups with different acid treatments that corresponded to pH 1, 2 and 3. The seeds that passed through the digestive tract of the animals presented a higher germination velocity index (p 0.05 when compared with the seeds without any treatment. The

  8. Selection of chemical markers for the quality control of medicinal plants of the genus Cecropia.

    Science.gov (United States)

    Rivera-Mondragón, Andrés; Ortíz, Orlando O; Bijttebier, Sebastiaan; Vlietinck, Arnold; Apers, Sandra; Pieters, Luc; Caballero-George, Catherina

    2017-12-01

    Several Cecropia (Cecropiaceae) species are traditionally used in Latin America for the treatment of a variety of diseases including diabetes, arterial hypertension, asthma, bronchitis, anxiety, and inflammation. At present, a number of commercial products based on these plants have been introduced into the market with very little information on methods for guaranteeing their quality and safety. This work proposes potential chemical markers for the quality control of the raw materials of Cecropia obtusifolia Bertol., Cecropia peltata L., Cecropia glaziovii Snethl., Cecropia pachystachya Trécul, and Cecropia hololeuca Miq. The Herbal Chemical Marker Ranking System (Herb MaRS) developed by the National Institute of Complementary Medicine (NICM) at the University of Western Sydney was used for selecting chemical markers for the quality control of selected medicinal species of Cecropia. This review covers the period from 1982 to 2016. Chlorogenic acid, flavonoidal glycosides (orientin, isoorientin, vitexin, isovitexin, and rutin), catechin, epicatechin, procyanidins (B2, B5, and C1), steroids (β-sitosterol), and triterpenoids (α-amyrin, pomolic, tormentic and ursolic acids) were selected as chemical markers for the quality control of the leaves. It is necessary to establish comprehensive standards for guaranteeing quality, safety and efficacy of herbal drugs. The selection of adequate chemical markers for quality control purposes requires a good knowledge about the chemical composition of medicinal plants and their associated biological properties. To the best of our knowledge this review article is the first to address the identification and quantitative determination of the chemical markers for the genus Cecropia.

  9. An HPLC-DAD method to quantification of main phenolic compounds from leaves of Cecropia species

    Energy Technology Data Exchange (ETDEWEB)

    Costa, Geison M.; Ortmann, Caroline F.; Schenkel, Eloir P.; Reginatto, Flavio H., E-mail: freginatto@hotmail.co [Universidade Federal de Santa Catarina (UFSC), Florianopolis (Brazil). Centro de Ciencias da Saude. Dept. de Ciencias Farmaceuticas

    2011-07-01

    An efficient and reproducible HPLC-DAD method was developed and validated for the simultaneous quantification of major compounds (chlorogenic acid, isoorientin, orientin and isovitexin) present in the leaves of two Cecropia species, C. glaziovii and C. pachystachya. From the leaves of C. glaziovii and C. pachystachya were isolated the C-glycosylflavones isoorientin and isovitexin and identified on both species chlorogenic acid (3-O-caffeoylquinic acid) and the O-glycosylflavonol isoquercitrin. The C-glycosylflavone orientin was isolated only from C. pachystachya. Chlorogenic acid was the major compound in both species (11.1 mg g{sup -1} of extract of C. glaziovii and 27.2 mg g{sup -1} of extract of C. pachystachya) and for the flavonoids quantified, isovitexin was the main C-glycosylflavonoid for C. glaziovii (4.6 mg g{sup -1} of extract) and isoorientin the main one for C. pachystachya (17.3 mg g{sup -1} of extract). (author)

  10. Vegetative propagation of Cecropia obtusifolia (Cecropiaceae

    Directory of Open Access Journals (Sweden)

    Louis M. LaPierre

    2001-12-01

    Full Text Available Cecropia is a relatively well-known and well-studied genus in the Neotropics. Methods for the successful propagation of C. obtusifolia Bertoloni. 1840 from cuttings and air layering are described, and the results of an experiment to test the effect of two auxins, naphthalene acetic acid (NAA and indole butyric acid (IBA, on adventitious root production in cuttings are presented. In general. C. obtusifolia cuttings respond well to adventitious root production (58.3 % of cuttings survived to root, but air layering was the better method (93 % of cuttings survived to root. The concentration of auxins used resulted in an overall significantly lower quality of roots produced compared with cuttings without auxin treatment. Future experiments using Cecropia could benefit from the use of isogenic plants produced by vegetative propagationCecropia es un género bien conocido y bien estudiado en los Neotrópicos. Se discuten métodos exitosos para la propagación de C. obtusifolia Bertoloni, 1840 de fragmentos de troncos y acodos aéreos. A continuación se presentan los resultados de un experimento para examinar los efectos de dos tipos de hormonas (NAA e IBA en la producción de raíces adventicias en fragmentos de troncos. En general, los fragmentos de C. abtusifalia responden bien en la producción de raíces adventicias (y sobreviven al azar 58.3% de los cortes, pero el método de acodos aéreos funcionó mejor (sobreviven al azar 93 %. El uso de hormonas resultó en raíces de baja calidad en comparación con cortes sin hormonas. Experimentos en el futuro que usan Cecropia pueden beneficiar al usar plantas isogénicas producidas por propagación vegetativa

  11. Secamiento Descendente del Yarumo (Cecropia Tessmanii

    Directory of Open Access Journals (Sweden)

    Obregón Botero. Rafael

    1972-12-01

    Full Text Available El estudio de muchas enfermedades que afectan plantas tropicales, como en el caso del género Cecropia, es muy difícil, debido a la carencia de bibliografía, ya que en muchos géneros no se han adelantado estudios, ni siquiera someros, de sus parásitos o de sus dolencias de origen no parasitario. En el caso presente, no fue posible encontrar dato alguno que pudiera encaminarnos en el estudio de esta nueva enfermedad del yarumo. Creemos, a pesar de que el presente trabajo no representa un estudio completo de problema, que tiene dos aspectos importantes: 1.El iniciar el estudio de los enemigos que pueda tener una planta tan poco estudiada y a la vez de tantas posibilidades como fuente de materia prima. 2.Relacionar los parásitos de este género, con enfermedades de otras plantas que viven en esos mismos climas y medios ambientes, esas ya sí, de reconocida importancia económica, como son las del cacao, el caucho y algunos árboles maderables.

  12. Distributional patterns of cecropia (Cecropiaceae: a panbiogeographic analysis

    Directory of Open Access Journals (Sweden)

    Franco Rosselli Pilar

    1997-06-01

    Full Text Available A panbiogeographic analysis of the distributional patterns of 60 species of Cecropia was carried out. Based on the distributional ranges of 36 species, we found eight generalized tracks for Cecropia species. whereas distributional patterns of 24 species were uninformative for the analysis. The major concentration of species of Cecropia is in the Neotropical Andean region. where there are three generalized tracks and two nodes. The northern Andes in Colombia and Ecuador are richer than the Central Andes in Perú. they contain two generalized tracks; one to the west and another to the east, formed by individual tracks of eight species each. There are four generalized tracks outside the Andean region: two in the Amazonian region in Guayana-Pará and in Manaus. one in Roraima. one in Serra do Mar in the Atlantic forest of Brazil and one in Central America. Speciation in Cecropia may be related to the Andean first uplift.Con base en la distribución de 60 especies del género Cecropia, se hizo un análisis panbiogeográfico. Se construyeron 8 trazos generalizados con base en el patrón de distribución de 36 especies; la distribución de las demás especies no aportaba información para la definición de los trazos. La región andina tiene la mayor concentración de especies de Cecropia representada por la presencia de tres trazos generalizados y dos nodos; los dos trazos con mayor número de especies se localizan en su parte norte, en Colombia y Ecuador y el otro en los Andes centrales en Perú. Se encontraron además, cuatro trazos extrandinos: dos en la región amazónica, en Pará-Guayana y en Manaus, uno en Roraima, uno en Serra do Mar en la Selva Atlánfíca del Brasil y uno en Centro América. La especiación en Cecropia parece estar relacionada con el primer levantamiento de los Andes.

  13. York University at TREC 2009: Chemical Track

    Science.gov (United States)

    2009-11-01

    York University at TREC 2009: Chemical Track Jiashu Zhao1, Xiangji Huang1, Zheng Ye1,2, Jianhan Zhu3 1 Information Retrieval and Knowledge Managment Lab...Information Retrieval and Knowledge Managment Lab,Toronto, Canada, 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S

  14. The Mirror DBMS at TREC-8

    NARCIS (Netherlands)

    de Vries, A.P.; Hiemstra, Djoerd; Voorhees, E.M; Harman, D.K.

    1999-01-01

    The database group at University of Twente participates in TREC8 using the Mirror DBMS, a prototype database system especially designed for multimedia and web retrieval. From a database perspective, the purpose has been to check whether we can get sufficient performance, and to prepare for the very

  15. IRIT at TREC 2014 Contextual Suggestion Track

    Science.gov (United States)

    2014-11-01

    both criteria users preferences and geographical location criteria. 1 Introduction TREC3 2014 Contextual Suggestion track examines search techniques...Contextual Retrieval Framework We address here the contextual retrieval problem as a multi-criteria decision making ( MCDM ) problem. The difficulty here

  16. The University of Amsterdam at TREC 2012

    Science.gov (United States)

    2012-11-01

    and fd . CTA(e, fd) Number of times all context is found in the document (e.g., “ music group” for Ba- sic Element ( music group). CTS(e, fd) Number of...times some context is found in the document (e.g., “ music ” for Ba- sic Element ( music group). Table 1: List of features we use. fd refers to the...per genre for TREC KBA. For each run the optimal cutoff is indicated; this is determined by considering the highest value for the F-measure for that

  17. Life history and environment of Cecropia latiloba in Amazonian floodplains.

    Science.gov (United States)

    Parolin, Pia

    2002-06-01

    Cecropia latiloba can be considered to be one of the most efficient colonizers of open areas in the nutrient-rich whitewater floodplains of the Amazon river. Its main strategy to be successful is the high tolerance towards waterlogging and submergence, and the fast vertical growth and reiteration capacity. This, and the tolerance of high irradiation and sediment deposition allow C. latiloba to form large monospecific stands on open sites, and thus the first closed canopy which represents the initial phase of a successional sequence which leads to highly diverse forests. This tree is extremely well adapted to the adverse growth conditions in Amazonian floodplains with prolonged periods of flooding and seedling submergence. The species occurs on the lowest levels in the flooding gradient. Although it belongs to the most often cited species under aspects of taxonomy, species distribution and general descriptions of the ecosystem, little has been published about its ecology. In the present paper the ecological, physiological and phenological characteristics of C. latiloba are described. It is an evergreen species which constantly produces new leaves. With flooding, leaf production is reduced but new leaves are flushed also with prolongued flooding. The peak of flowering and fruiting are in the flooded period. When mature, the fruits are dispersed mainly by water and fish. Seed germination occurs, without dormancy, within 5-13 days after water retreat. In the 7 months before the first flooded period seedlings reach 1 m of height, and height growth increases until 15-20 m are achieved. Photosynthetic assimilation is high, with values of up to 21 mumol CO2 m-2s-1. C. latiloba is a very flood tolerant species, and waterlogged seedlings continuously produce new leaves and adventitious roots.

  18. The status of Cecropia (Urticaceae) introductions in Malesia: addressing the confusion

    NARCIS (Netherlands)

    Conn, B.J.; Hadiah, J.T.; Webber, B.L.

    2012-01-01

    As part of the great global movement of plants in the 18th and 19th centuries, many valuable and commercial plants were sent from the Neotropics to Europe as seeds or as live specimens. Cecropia (Urticaceae) was in cultivation in England in 1789, yet species delimitation was not well-understood

  19. Life history and environment of Cecropia latiloba in Amazonian floodplains

    Directory of Open Access Journals (Sweden)

    Pia Parolin

    2002-06-01

    Full Text Available Cecropia latiloba can be considered to be one of the most efficient colonizers of open areas in the nutrient-rich whitewater floodplains of the Amazon river. Its main strategy to be successful is the high tolerance towards waterlogging and submergence, and the fast vertical growth and reiteration capacity. This, and the tolerance of high irradiation and sediment deposition allow C. latiloba to form large monospecific stands on open sites, and thus the first closed canopy which represents the initial phase of a successional sequence which leads to highly diverse forests. This tree is extremely well adapted to the adverse growth conditions in Amazonian floodplains with prolongued periods of flooding and seedling submergence. The species occurs on the lowest levels in the flooding gradient. Although it belongs to the most often cited species under aspects of taxonomy, species distribution and general descriptions of the ecosystem, little has been published about its ecology. In the present paper the ecological, physiological and phenological characteristics of C. latiloba are described. It is an evergreen species which constantly produces new leaves. With flooding, leaf production is reduced but new leaves are flushed also with prolongued flooding. The peak of flowering and fruiting are in the flooded period. When mature, the fruits are dispersed mainly by water and fish. Seed germination occurs, without dormancy, within 5-13 days after water retreat. In the 7 months before the first flooded period seedlings reach 1 m of height, and height growth increases until a height of 15-20 m is achieved. Photosynthetic assimilation is high, with values of up to 21 mmol CO2m-2s-1 . C. latiloba is a very flood tolerant species, and waterlogged seedlings continuously produce new leaves and adventitiuos rootsCecropia latiloba puede ser considerada una de las especies colonizadoras más eficientes de áreas abiertas en las llanuras inundadas de agua dulce, rica

  20. York University at TREC 2012: Medical Records Track

    Science.gov (United States)

    2012-11-01

    York University at TREC 2012: Medical Records Track Jun Miao, Zheng Ye, Jimmy Huang Information Retrieval and Knowledge Managment Lab York University...Information Retrieval and Knowledge Managment Lab,Toronto, Canada, 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND

  1. Overview of the TREC 2014 Federated Web Search Track

    NARCIS (Netherlands)

    Demeester, Thomas; Trieschnigg, Rudolf Berend; Nguyen, Dong-Phuong; Zhou, Ke; Hiemstra, Djoerd

    2014-01-01

    The TREC Federated Web Search track facilitates research in topics related to federated web search, by providing a large realistic data collection sampled from a multitude of online search engines. The FedWeb 2013 challenges of Resource Selection and Results Merging challenges are again included in

  2. Overview of the TREC 2013 Federated Web Search Track

    NARCIS (Netherlands)

    Demeester, Thomas; Trieschnigg, Rudolf Berend; Nguyen, Dong-Phuong; Hiemstra, Djoerd

    2014-01-01

    The TREC Federated Web Search track is intended to promote research related to federated search in a realistic web setting, and hereto provides a large data collection gathered from a series of online search engines. This overview paper discusses the results of the first edition of the track, FedWeb

  3. Overview of the TREC 2013 Federated Web Search Track

    NARCIS (Netherlands)

    Demeester, Thomas; Trieschnigg, Rudolf Berend; Nguyen, Dong-Phuong; Hiemstra, Djoerd

    The TREC Federated Web Search track is intended to promote research related to federated search in a realistic web setting, and hereto provides a large data collection gathered from a series of online search engines. This overview paper discusses the results of the first edition of the track, FedWeb

  4. T-REC: Strengthening capacity for blood transfusion research in ...

    African Journals Online (AJOL)

    T-REC provides funding and support for PhD students undertaking research addressing the highest priority needs of the transfusion services, a Professional Diploma course in Project Design and Management to build the competence and confidence of health service professionals in research and drive the development of ...

  5. A Visual Exploration of the Orderliness of TREC Relevance Judgments.

    Science.gov (United States)

    Rorvig, Mark

    1999-01-01

    Discussion of information-retrieval test collections focuses on a study of TREC documents that used scaling and visualization of documents using a maximum-likelihood estimation method to examine the relevance of documents retrieved. Discusses clustering, similarity measures, isomorphism, and semantic relevance. (LRW)

  6. York University at TREC 2012: CrowdSourcing Track

    Science.gov (United States)

    2012-11-01

    Retrieval and Knowledge Managment Lab,Toronto, Canada, 8. PERFORMING ORGANIZATION REPORT NUMBER 9. SPONSORING/MONITORING AGENCY NAME(S) AND ADDRESS(ES...York University at TREC 2012: CrowdSourcing Track Qinmin Hu1,2, Zhi Xu1,3, Xiangji Huang1,3, Zheng Ye1 1 Information Retrieval and Knowledge ... Managment Lab, York University, Toronto, Canada 2Department of Computer Science & Engineering, York University, Toronto, Canada 3School of Information

  7. Overview of the TREC 2014 Federated Web Search Track

    OpenAIRE

    Demeester, Thomas; Trieschnigg, Dolf; Nguyen, Dong; Hiemstra, Djoerd; Zhou, Ke

    2014-01-01

    The TREC Federated Web Search track facilitates research in topics related to federated web search, by providing a large realistic data collection sampled from a multitude of online search engines. The FedWeb 2013 challenges of Resource Selection and Results Merging challenges are again included in FedWeb 2014, and we additionally introduced the task of vertical selection. Other new aspects are the required link between the Resource Selection and Results Merging, and the importance of diversi...

  8. Overview of the TREC 2013 federated web search track

    OpenAIRE

    Demeester, Thomas; Trieschnigg, D; Nguyen, D; Hiemstra, D

    2013-01-01

    The TREC Federated Web Search track is intended to promote research related to federated search in a realistic web setting, and hereto provides a large data collection gathered from a series of online search engines. This overview paper discusses the results of the first edition of the track, FedWeb 2013. The focus was on basic challenges in federated search: (1) resource selection, and (2) results merging. After an overview of the provided data collection and the relevance judgments for the ...

  9. CARACTERIZACIÓN BIOQUÍMICA PARCIAL DE PROTEÍNAS ALERGIÉNICAS DE FRAXINUS SINENSIS Y CECROPIA SP.

    OpenAIRE

    Rodríguez, Adriana; Departamento de Microbiología, Facultad de Ciencias, Pontificia Universidad Javeriana, Bogotá; Leal, Francisco; Hospital Infantil Lorenzita Villegas de Santos, Bogotá

    2013-01-01

    The allergenic capabilities ofthe poli en of Fraxinus sinensis (Urapán) and Cecropia sp. (Y arumo) were determined in patients with respiratory allergies in the city ofBogotá. Of a total of207 patients wbo were subjected to therelevant allergy skin tests, 20 (9.66%) were positive for F. sinensis and 6 (2.9%) for the extract from Cecropia sp. The allergenicity was confirmed by the determination of specific Iinmunoglobulin E (lgE). Of the twenty patients positive for F. sinensis, only 6 ofthem ...

  10. Distributed Non-Parametric Representations for Vital Filtering: UW at TREC KBA 2014

    Science.gov (United States)

    2014-11-01

    Conference (TREC), 2013. Elman, Jeffrey L. Finding structure in time. COGNITIVE SCI- ENCE, pp. 179–211, 1990. Frank, John R., Kleiman -Weiner, Max...ceedings of the Twenty-First Text REtrieval Conference (TREC 2012), 2012. Frank, John R., Kleiman -Weiner, Max, Roberts, Daniel A., Voorhees, Ellen, and

  11. Continental-scale patterns of Cecropia reproductive phenology: evidence from herbarium specimens.

    Science.gov (United States)

    Zalamea, Paul-Camilo; Munoz, François; Stevenson, Pablo R; Paine, C E Timothy; Sarmiento, Carolina; Sabatier, Daniel; Heuret, Patrick

    2011-08-22

    Plant phenology is concerned with the timing of recurring biological events. Though phenology has traditionally been studied using intensive surveys of a local flora, results from such surveys are difficult to generalize to broader spatial scales. In this study, contrastingly, we assembled a continental-scale dataset of herbarium specimens for the emblematic genus of Neotropical pioneer trees, Cecropia, and applied Fourier spectral and cospectral analyses to investigate the reproductive phenology of 35 species. We detected significant annual, sub-annual and continuous patterns, and discuss the variation in patterns within and among climatic regions. Although previous studies have suggested that pioneer species generally produce flowers continually throughout the year, we found that at least one third of Cecropia species are characterized by clear annual flowering behaviour. We further investigated the relationships between phenology and climate seasonality, showing strong associations between phenology and seasonal variations in precipitation and temperature. We also verified our results against field survey data gathered from the literature. Our findings indicate that herbarium material is a reliable resource for use in the investigation of large-scale patterns in plant phenology, offering a promising complement to local intensive field studies.

  12. Earthworm influence on N availability and the growth of Cecropia schreberiana in tropical pasture and forest soils

    Science.gov (United States)

    G. Gonzalez; X. Zou

    1999-01-01

    This greenhouse study examines the effects of Pontoscolex corethrurus on the growth of Cecropia scheberiana in forest and pasture soils. Four treatments (0, 2, 20 worms and 0 worms + urea fertilizer) were applied to the soils to test if earthworms affect nitrogen availability, and consequently the growth of C. scheberiana. We recorded the number of seedlings, leaves,...

  13. The genus Cecropia: a biological clock to estimate the age of recently disturbed areas in the Neotropics.

    Directory of Open Access Journals (Sweden)

    Paul-Camilo Zalamea

    Full Text Available Forest successional processes following disturbance take decades to play out, even in tropical forests. Nonetheless, records of vegetation change in this ecosystem are scarce, increasing the importance of the chronosequence approach to study forest recovery. However, this approach requires accurate dating of secondary forests, which until now was a difficult and/or expensive task. Cecropia is a widespread and abundant pioneer tree genus of the Neotropics. Here we propose and validate a rapid and straightforward method to estimate the age of secondary forest patches based on morphological observations of Cecropia trees. We found that Cecropia-inferred ages were highly correlated with known ages of the forest. We also demonstrate that Cecropia can be used to accurately date disturbances and propose twenty-one species distributed all over the geographical range of the genus as potential secondary forest chronometer species. Our method is limited in applicability by the maximal longevity of Cecropia individuals. Although the oldest chronosequence used in this study was 20 years old, we argue that at least for the first four decades after disturbance, the method described in this study provides very accurate estimations of secondary forest ages. The age of pioneer trees provides not only information needed to calculate the recovery of carbon stocks that would help to improve forest management, but also provides information needed to characterize the initial floristic composition and the rates of species remigration into secondary forest. Our contribution shows how successional studies can be reliably and inexpensively extended without the need to obtain forest ages based on expensive or potentially inaccurate data across the Neotropics.

  14. Qualitative and quantitative analysis of the phenolic content of Connarus var. angustifolius, Cecropia obtusa, Cecropia palmata and Mansoa alliacea based on HPLC-DAD and UHPLC-ESI-MS/MS

    Directory of Open Access Journals (Sweden)

    Fernanda B. Pires

    Full Text Available ABSTRACT The phenolic content of the medicinal species Connarus perrottetti var. angustifolius Radlk., Connaraceae, Cecropia obtuse Trécul, Cecropia palmata Willd., Urticaceae; and Mansoa alliacea (Lam. A.H.Gentry, Bignoniaceae, collected in three different years was evaluated. Plant infusions and hydroalcoholic, butanol and ethyl acetate extracts were analyzed by high-performance liquid chromatography with diode array detection. In order to endorse these results, analysis by electrospray mass spectrometry was also performed. Were identified: gallic acid, catechin, caffeic acid, ferulic acid, rutin, quercitrin and resveratrol. C. perrottetti showed greater diversity of polyphenols. M. alliacea had the higher concentration of caffeic acid even though it was found in all species. Catechin was the major antioxidant, but was not detected in M. alliacea. However, we discuss the popular use of these species, as well as their phenolic constitution and the interannual distribution of phenolic compounds.

  15. Cecropia as a food resource for bats in French Guiana and the significance of fruit structure in seed dispersal and longevity.

    Science.gov (United States)

    Lobova, Tatyana A; Mori, Scott A; Blanchard, Frédéric; Peckham, Heather; Charles-Dominique, Pierre

    2003-03-01

    Cecropia (Cecropiaceae) is a Neotropical genus of pioneer plants. A review of bat/plant dispersal interactions revealed that 15 species of Cecropia are consumed by 32 species of bats. In French Guiana, bats were captured in primary and secondary forests, yielding 936 fecal samples with diaspores, among which 162 contained fruits of C. obtusa, C. palmata, and C. sciadophylla. A comparative morphological and anatomical study of fruits and seeds taken directly from herbarium specimens, bat feces, and an experimental soil seed bank was made. Contrary to previous reports, the dispersal unit of Cecropia is the fruit not the seed. Bats consume the infructescence, digest pulp derived from the enlarged, fleshy perianth, and defecate the fruits. The mucilaginous pericarp of Cecropia is described. The external mucilage production of Cecropia may facilitate endozoochory. The exocarp and part of the mesocarp may be lost after passage through the digestive tract of bats, but fruits buried for a year in the soil seed bank remain structurally unchanged. Fruit characters were found to be useful for identifying species of bat-dispersed Cecropia. Bat dispersal is not necessary for seed germination but it increases seed survival and subsequent germination. Fruit structure plays a significant role in seed longevity.

  16. PolarTREC-Teachers and Researchers Exploring and Collaborating: Bringing Polar Research to the Classroom

    Science.gov (United States)

    Warnick, W. K.; Warburton, J.; Breen, K.; Wiggins, H. V.; Larson, A.; Behr, S.

    2006-12-01

    PolarTREC-Teachers and Researchers Exploring and Collaborating is a three-year (2007-2009) teacher professional development program that pairs K-12 teachers with researchers to improve science education through authentic polar research experience. PolarTREC builds on the strengths of the existing TREC program in the Arctic, an NSF supported program managed by the Arctic Research Consortium of the US (ARCUS), to embrace a wider range of research activities in the Arctic and Antarctic. PolarTREC uses a Teacher Research Experience (TRE) model to foster the integration of research and education to produce a legacy of long-term teacher-researcher collaborations, improved teacher content knowledge through experiences in scientific inquiry, and broad public interest and engagement in polar science. PolarTREC will enable thirty-six teachers to spend two to six weeks in the Arctic or Antarctic, working closely with researchers investigating a wide range of topics such as sea-ice dynamics, terrestrial ecology, marine biology, atmospheric chemistry, and long-term climate change. With the help of their host researcher and the research team, teachers will develop the experience and tools necessary to teach science through scientific inquiry and investigation based on real-world experiences. While in the field, teachers and researchers will communicate extensively with their colleagues, communities, and hundreds of students of all ages across the globe, using a variety of tools including satellite phones, online journals, podcasts and interactive "Live from IPY" calls and web-based seminars. The online outreach elements of the project convey these experiences to a broad audience far beyond the classrooms of the PolarTREC teachers. In addition to field research experiences, PolarTREC will support teacher professional development and a sustained community of teachers, scientists, and the public through workshops, Internet seminars, an e-mail listserve, and ongoing teacher

  17. The 2011-2016 Transdisciplinary Research on Energetics and Cancer (TREC) initiative: rationale and design.

    Science.gov (United States)

    Patterson, Ruth E; Colditz, Graham A; Hu, Frank B; Schmitz, Kathryn H; Ahima, Rexford S; Brownson, Ross C; Carson, Kenneth R; Chavarro, Jorge E; Chodosh, Lewis A; Gehlert, Sarah; Gill, Jeff; Glanz, Karen; Haire-Joshu, Debra; Herbst, Karen Louise; Hoehner, Christine M; Hovmand, Peter S; Irwin, Melinda L; Jacobs, Linda A; James, Aimee S; Jones, Lee W; Kerr, Jacqueline; Kibel, Adam S; King, Irena B; Ligibel, Jennifer A; Meyerhardt, Jeffrey A; Natarajan, Loki; Neuhouser, Marian L; Olefsky, Jerrold M; Proctor, Enola K; Redline, Susan; Rock, Cheryl L; Rosner, Bernard; Sarwer, David B; Schwartz, J Sanford; Sears, Dorothy D; Sesso, Howard D; Stampfer, Meir J; Subramanian, S V; Taveras, Elsie M; Tchou, Julia; Thompson, Beti; Troxel, Andrea B; Wessling-Resnick, Marianne; Wolin, Kathleen Y; Thornquist, Mark D

    2013-04-01

    Recognition of the complex, multidimensional relationship between excess adiposity and cancer control outcomes has motivated the scientific community to seek new research models and paradigms. The National Cancer Institute developed an innovative concept to establish a center grant mechanism in nutrition, energetics, and physical activity, referred to as the Transdisciplinary Research on Energetics and Cancer (TREC) Initiative. This paper gives an overview of the 2011-2016 TREC Collaborative Network and the 15 research projects being conducted at the centers. Four academic institutions were awarded TREC center grants in 2011: Harvard University, University of California San Diego, University of Pennsylvania, and Washington University in St. Louis. The Fred Hutchinson Cancer Research Center is the Coordination Center. The TREC research portfolio includes three animal studies, three cohort studies, four randomized clinical trials, one cross-sectional study, and two modeling studies. Disciplines represented by TREC investigators include basic science, endocrinology, epidemiology, biostatistics, behavior, medicine, nutrition, physical activity, genetics, engineering, health economics, and computer science. Approximately 41,000 participants will be involved in these studies, including children, healthy adults, and breast and prostate cancer survivors. Outcomes include biomarkers of cancer risk, changes in weight and physical activity, persistent adverse treatment effects (e.g., lymphedema, urinary and sexual function), and breast and prostate cancer mortality. The NIH Science of Team Science group will evaluate the value added by this collaborative science. However, the most important outcome will be whether this transdisciplinary initiative improves the health of Americans at risk of cancer as well as cancer survivors.

  18. Differences on post-fire regeneration of the pioneer trees Cecropia glazioui and Trema micrantha in a lowland Brazilian Atlantic Forest

    Directory of Open Access Journals (Sweden)

    Dalva M Silva-Matos

    2005-06-01

    Full Text Available A study of natural post-fire succession was carried out in a disturbed vegetation around fragments of the Atlantic Rain Forest (National Biological Reserve of Poço das Antas (22 °30 ’-22 °33 ’S,42 °15 ’-42 °19 ’W, Rio de Janeiro State.All the pre-fire individuals of Cecropia and Trema in the area were numbered with plastic labels.In order to check for the presence of new sprouts and mortality,two other censuses were carried out,at 3 and 12 months after the fire.The dominant species were:Pteridium aquilinum,Panicum maximum,Trema micrantha and Cecropia glazioui. Few days after the passage of fire, grasses and ferns spread their area,while the stands of Trema and Cecropia were completely burned. Most of individuals of Cecropia produced some sprouts while most of individuals of Trema died.However,a great number of seedlings of Trema were recruited while only one single seedling of Cecropia were observed during a period of one year.Most of these seedlings died through the year while the sprouts were already reproducing.The uses of Cecropia in places where fire is recurrent could be more appropriate because of its higher chance of survival and faster recovering ability after fire.Rev.Biol.Trop.53(1-2:1-4.Epub 2005 Jun 24Se realizó un estudio sobre la sucesión natural después del fuego en una vegetación alrededor de fragmentos de la selva lluviosa atlántica (Reserva Biológica Nacional de Poço das Antas (22° 30 ’-22° 33 ’ S, 42° 15’- 42° 19’ W, Estado de Río de Janeiro.Todos los individuos de Cecropia y Trema previos del fuego en el área fueron numerados con marcas plásticas. Se realizaron otros dos censos, 3 y 12 meses después del fuego con el objetivo de detectar mortalidad y buscar la presencia de nuevos brotes. Las especies dominantes fueron: Pteridium aquilinum, Panicum maximum, Trema micrantha y Cecropia glazioui. Pocos días después del paso del fuego,los pastos y helechos se dispersaron por el área, mientras

  19. Retrospective TREC testing of newborns with Severe Combined Immunodeficiency and other primary immunodeficiency diseases.

    Science.gov (United States)

    Jilkina, O; Thompson, J R; Kwan, L; Van Caeseele, P; Rockman-Greenberg, C; Schroeder, M L

    2014-01-01

    In Manitoba, Canada, the overall incidence of Severe Combined Immunodeficiency (SCID) is three-fold higher than the national average, with SCID overrepresented in two population groups: Mennonites and First Nations of Northern Cree ancestries. T-cell receptor excision circle (TREC) assay is being used increasingly for neonatal screening for SCID in North America. However, the majority of SCID patients in Manitoba are T-cell-positive. Therefore it is likely that the TREC assay will not identify these infants. The goal of this study was to blindly and retrospectively perform TREC analysis in confirmed SCID patients using archived Guthrie cards. Thirteen SCID patients were tested: 5 T-negative SCID (3 with adenosine deaminase deficiency, 1 with CD3δ deficiency, and 1 unclassified) and 8 T-positive SCID (5 with zeta chain-associated protein kinase (ZAP70) deficiency and 3 with inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (IKKβ) deficiency). As a non-SCID patient group, 5 Primary Immunodeficiency Disease (PID) patients were studied: 1 T-negative PID (cartilage-hair hypoplasia) and 4 T-positive PID (2 common immune deficiency (CID), 1 Wiskott-Aldrich syndrome, and 1 X-linked lymphoproliferative disease). Both patient groups required hematopoietic stem cell transplantation. In addition, randomly-selected de-identified controls (n = 982) were tested. Results : all T-negative SCID and PID had zero TRECs. Low-TRECs were identified in 2 ZAP70 siblings, 1 CID patient as well as 5 preterm, 1 twin, and 4 de-identified controls. Conclusions : TREC method will identify T-negative SCID and T-negative PID. To identify other SCID babies, newborn screening in Manitoba must include supplemental targeted screening for ethnic-specific mutations.

  20. Retrospective TREC testing of newborns with Severe Combined Immunodeficiency and other primary immunodeficiency diseases

    Directory of Open Access Journals (Sweden)

    O. Jilkina

    2014-01-01

    Full Text Available In Manitoba, Canada, the overall incidence of Severe Combined Immunodeficiency (SCID is three-fold higher than the national average, with SCID overrepresented in two population groups: Mennonites and First Nations of Northern Cree ancestries. T-cell receptor excision circle (TREC assay is being used increasingly for neonatal screening for SCID in North America. However, the majority of SCID patients in Manitoba are T-cell-positive. Therefore it is likely that the TREC assay will not identify these infants. The goal of this study was to blindly and retrospectively perform TREC analysis in confirmed SCID patients using archived Guthrie cards. Thirteen SCID patients were tested: 5 T-negative SCID (3 with adenosine deaminase deficiency, 1 with CD3δ deficiency, and 1 unclassified and 8 T-positive SCID (5 with zeta chain-associated protein kinase (ZAP70 deficiency and 3 with inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (IKKβ deficiency. As a non-SCID patient group, 5 Primary Immunodeficiency Disease (PID patients were studied: 1 T-negative PID (cartilage-hair hypoplasia and 4 T-positive PID (2 common immune deficiency (CID, 1 Wiskott–Aldrich syndrome, and 1 X-linked lymphoproliferative disease. Both patient groups required hematopoietic stem cell transplantation. In addition, randomly-selected de-identified controls (n = 982 were tested. Results: all T-negative SCID and PID had zero TRECs. Low-TRECs were identified in 2 ZAP70 siblings, 1 CID patient as well as 5 preterm, 1 twin, and 4 de-identified controls. Conclusions: TREC method will identify T-negative SCID and T-negative PID. To identify other SCID babies, newborn screening in Manitoba must include supplemental targeted screening for ethnic-specific mutations.

  1. Re-ranking via User Feedback: Georgetown University at TREC 2015 DD Track

    Science.gov (United States)

    2015-11-20

    involved in a search process, the user and the search engine. In TREC DD, the user is modeled by a simulator, called “ jig ”. The jig and the search engine...exchange many messages among themselves, including the relevant passages returned by the jig , user cost spent on examining the documents, etc. In...simulating user is provided by TREC 2015 DD Track organizer, and is called “ jig ”. There are 118 search topics in total. For each search topic, a short

  2. PolarTREC-Teachers and Researchers Exploring and Collaborating: Innovative Science Education from the Poles to the World

    Science.gov (United States)

    Warnick, W. K.; Warburton, J.; Breen, K.; Wiggins, H. V.; Larson, A.; Behr, S.

    2006-12-01

    PolarTREC-Teachers and Researchers Exploring and Collaborating is a three-year (2007-2009) teacher professional development program celebrating the International Polar Year (IPY) that will advance polar science education by bringing K-12 educators and polar researchers together in hands-on field experiences in the Arctic and Antarctic. PolarTREC builds on the strengths of the existing TREC program in the Arctic, an NSF supported program managed by the Arctic Research Consortium of the US (ARCUS), to embrace a wide range of activities occurring at both poles during and after IPY. PolarTREC will foster the integration of research and education to produce a legacy of long-term teacher-researcher collaborations, improved teacher content knowledge through experiences in scientific inquiry, and broad public interest and engagement in polar science and IPY. PolarTREC will enable thirty-six teachers to spend two to six weeks in the Arctic or Antarctic, working closely with researchers investigating a wide range of IPY science themed topics such as sea-ice dynamics, terrestrial ecology, marine biology, atmospheric chemistry, and long-term climate change. While in the field, teachers and researchers will communicate extensively with their colleagues, communities, and hundreds of students of all ages across the globe, using a variety of tools including satellite phones, online journals, podcasts and interactive "Live from IPY" calls and web-based seminars. The online outreach elements of the project convey these experiences to a broad audience far beyond the classrooms of the PolarTREC teachers. In addition to field research experiences, PolarTREC will support teacher professional development and a sustained community of teachers, scientists, and the public through workshops, Internet seminars, an e-mail listserve, and teacher peer groups. For further information on PolarTREC, contact Wendy Warnick, ARCUS Executive Director at warnick@arcus.org or 907-474-1600 or visit www.arcus.org/trec/

  3. A new look at discontinuous respiration in pupae of Hyalophora cecropia (Lepidoptera: Saturniidae): Haemocoelic pressure, extracardiac pulsations and O2 consumption

    Czech Academy of Sciences Publication Activity Database

    Sláma, Karel

    2010-01-01

    Roč. 107, č. 4 (2010), s. 487-507 ISSN 1210-5759 Institutional research plan: CEZ:AV0Z50070508 Keywords : Saturniidae * Hyalophora cecropia * respiratory acidaemia Subject RIV: ED - Physiology Impact factor: 0.945, year: 2010 http://www.eje.cz/scripts/viewabstract.php?abstract=1559

  4. The TREC/KREC assay for the diagnosis and monitoring of patients with DiGeorge syndrome.

    Directory of Open Access Journals (Sweden)

    Eva Froňková

    Full Text Available DiGeorge syndrome (DGS presents with a wide spectrum of thymic pathologies. Nationwide neonatal screening programs of lymphocyte production using T-cell recombination excision circles (TREC have repeatedly identified patients with DGS. We tested what proportion of DGS patients could be identified at birth by combined TREC and kappa-deleting element recombination circle (KREC screening. Furthermore, we followed TREC/KREC levels in peripheral blood (PB to monitor postnatal changes in lymphocyte production.TREC/KREC copies were assessed by quantitative PCR (qPCR and were related to the albumin control gene in dry blood spots (DBSs from control (n = 56, severe immunodeficiency syndrome (SCID, n = 10 and DGS (n = 13 newborns. PB was evaluated in DGS children (n = 32, in diagnostic samples from SCID babies (n = 5 and in 91 controls.All but one DGS patient had TREC levels in the normal range at birth, albeit quantitative TREC values were significantly lower in the DGS cohort. One patient had slightly reduced KREC at birth. Postnatal DGS samples revealed reduced TREC numbers in 5 of 32 (16% patients, whereas KREC copy numbers were similar to controls. Both TREC and KREC levels showed a more pronounced decrease with age in DGS patients than in controls (p < 0.0001 for both in a linear model. DGS patients had higher percentages of NK cells at the expense of T cells (p < 0.0001. The patients with reduced TREC levels had repeated infections in infancy and developed allergy and/or autoimmunity, but they were not strikingly different from other patients. In 12 DGS patients with paired DBS and blood samples, the TREC/KREC levels were mostly stable or increased and showed similar kinetics in respective patients.The combined TREC/KREC approach with correction via control gene identified 1 of 13 (8% of DiGeorge syndrome patients at birth in our cohort. The majority of patients had TREC/KREC levels in the normal range.

  5. Evaluating Stream Filtering for Entity Profile Updates for TREC 2013 (KBA Track Overview)

    Science.gov (United States)

    2013-11-01

    Evaluating Stream Filtering for Entity Profile Updates for TREC 2013 (KBA Track Overview) 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER...the corpus.     2012   2013   Corpus   7 months (4,973 hours)   > 400M documents   40% English   Oc 2011 to Apr 2012.   17 months

  6. Twenty-One at TREC-8: using Language Technology for Information Retrieval

    NARCIS (Netherlands)

    Kraaij, Wessel; Pohlmann, Renée; Hiemstra, Djoerd; Voorhees, E.M; Harman, D.K.

    2000-01-01

    This paper describes the official runs of the Twenty-One group for TREC-8. The Twenty-One group participated in the Ad-hoc, CLIR, Adaptive Filtering and SDR tracks. The main focus of our experiments is the development and evaluation of retrieval methods that are motivated by natural language

  7. CWI and TU Delft at TREC 2013: Contextual Suggestion, Federated Web Search, KBA, and Web Tracks

    NARCIS (Netherlands)

    A. Bellogín Kouki (Alejandro); G.G. Gebremeskel (Gebre); J. He (Jiyin); J.J.P. Lin (Jimmy); A. Said (Alan); T. Samar (Thaer); A.P. de Vries (Arjen); J.B.P. Vuurens (Jeroen)

    2014-01-01

    htmlabstractThis paper provides an overview of the work done at the Centrum Wiskunde & Informatica (CWI) and Delft University of Technology (TU Delft) for different tracks of TREC 2013. We participated in the Contextual Suggestion Track, the Federated Web Search Track, the Knowledge Base

  8. Newborn Screening for Severe Combined Immunodeficiency-A History of the TREC Assay

    Directory of Open Access Journals (Sweden)

    Mary T. Bausch-Jurken

    2017-06-01

    Full Text Available Infants born with T cell lymphopenias, especially severe combined immunodeficiency (SCID are at risk for serious, often fatal infections without intervention within the first year or two of life. The majority of these disorders can be detected through the use of the T cell recombination excision circle assay (TREC assay. The TREC assay detects the presence of non-replicating, episomal DNA that is formed during T cell development. This assay initially developed to measure thymic output during aging and HIV infection, has undergone modifications for the purpose of newborn screening (NBS for SCID. To meet the requirements for inclusion on NBS panels, the assay needed to utilize blood from dried blood spots on NBS cards, and be both sensitive and specific, avoiding the costs of false positives. Currently, the assay relies upon real time, quantitative PCR (RT-qPCR to detect TRECs in punches taken from dried blood spots. This review seeks to highlight some of the early work leading up to the initial implementation of the TREC assay for SCID detection, and the subsequent revisions made to optimize the assay.

  9. PolarTREC-Celebrating the Legacy of the IPY Through Researcher-Educator Partnerships

    Science.gov (United States)

    Timm, K.; Warburton, J.; Larson, A. M.

    2009-12-01

    Polar TREC-Teachers and Researchers Exploring and Collaborating, a three-year (2007-2009) NSF-funded program, has matched over 40 teachers with polar researchers working in multiple scientific disciplines for 2-8 week Teacher Research Experiences (TRE) in the Arctic and Antarctica during the IPY. PolarTREC contributes to the legacy of the IPY through the creation and dissemination of polar education resources, prolonged teacher-researcher relationships, and contributions to scholarly knowledge on the impacts of TRE's. Products developed during PolarTREC are helping to sustain the widespread interest and enthusiasm in the polar regions generated during the IPY. During their expeditions, participating teachers brought science and information about profound changes at the poles to school, community, and professional audiences through web-based communications, journals, discussion forums, multimedia, and live events. PolarTREC teachers constructed nearly 100 classroom lesson plans and activities as products of their experiences. Live events from the field attracted over 11,000 participants, primarily K-12 students. Although the field experience is central to the PolarTREC TRE Model, many participants cite the relationship they built with their teacher/researcher as one of the best outcomes. Through personal communications, presentations at professional conferences, and continued support of each other’s work through classroom visits or joint proposal development, teachers and researchers have maintained the mutually beneficial relationships established during the IPY. Participating scientists gained access to professional educators with expertise in translating research approaches and results into programs. The need for researchers to explain their research and “boil it down to the raw essence” helped many see how their work fits into a bigger picture, often helping them communicate outside their scientific discipline and to diverse public audiences. Teachers, on

  10. TRIAGEM NEONATAL DE IMUNODEFICIÊNCIAS GRAVES COMBINADAS POR MEIO DE TRECS E KRECS: SEGUNDO ESTUDO PILOTO NO BRASIL

    Directory of Open Access Journals (Sweden)

    Marilia Pyles P. Kanegae

    Full Text Available RESUMO Objetivo: Validar a quantificação de T-cell receptor excision circles (TRECs e kappa-deleting recombination circles (KRECs por reação em cadeia de polimerase (polymerase chain reaction, PCR em tempo real (qRT-PCR, para triagem neonatal de imunodeficiências primárias que cursam com defeitos nas células T e/ou B no Brasil. Métodos: Amostras de sangue de recém-nascidos (RN e controles foram coletadas em papel-filtro. O DNA foi extraído e os TRECs e KRECs foram quantificados por reação duplex de qRT-PCR. O valor de corte foi determinado pela análise de Receiver Operating Characteristics Curve, utilizando-se o programa Statistical Package for the Social Sciences (SSPS (IBM®, Armonk, NY, EUA. Resultados: 6.881 amostras de RN foram analisadas quanto à concentração de TRECs e KRECs. Os valores de TRECs variaram entre 1 e 1.006 TRECs/µL, com média e mediana de 160 e 139 TRECs/µL, respectivamente. Três amostras de pacientes diagnosticados com imunodeficiência grave combinada (severe combined immunodeficiency, SCID apresentaram valores de TRECs abaixo de 4/µL e um paciente com Síndrome de DiGeorge apresentou TRECs indetectáveis. Os valores de KRECs encontraram-se entre 10 e 1.097 KRECs/µL, com média e mediana de 130 e 108 KRECs/µL, e quatro pacientes com diagnóstico de agamaglobulinemia tiveram resultados abaixo de 4 KRECs/µL. Os valores de corte encontrados foram 15 TRECs/µL e 14 KRECs/µL, e foram estabelecidos de acordo com a análise da Receiver Operating Characteristics Curve, com sensibilidade de 100% para detecção de SCID e agamaglobulinemia, respectivamente. Conclusões: A quantificação de TRECs e KRECs foi capaz de diagnosticar crianças com linfopenias T e/ou B em nosso estudo, validando a técnica e dando o primeiro passo para a implementação da triagem neonatal em grande escala no Brasil.

  11. BJUT at TREC 2015 Microblog Track: Real-Time Filtering Using Non-negative Matrix Factorization

    Science.gov (United States)

    2015-11-20

    BJUT at TREC 2015 Microblog Track: Real-Time Filtering Using Non- negative Matrix Factorization Chaoyang Li1,2,3, Zhen Yang1,2,3,⇤, Kefeng Fan1,4 1...results for scenario B: periodic e- mail digest. In this ad hoc search task, we introduced a real-time filtering framework using non- negative ma- trix... negative ma- trix factorization based Microblog retrieval model (N- MF Framework). Then after a review of the potential in- fluencing factors in

  12. NASA IceBridge and PolarTREC - Education and Outreach Partnership

    Science.gov (United States)

    Bartholow, S.; Warburton, J.; Beck, J.; Woods, J. E.

    2015-12-01

    PolarTREC-Teachers and Researchers Exploring and Collaborating, a teacher professional development program, began with the International Polar Year in 2004 and continues today in the United States. PolarTREC has worked specifically with OIB for 3 years and looking forward to ongoing collaboration. PolarTREC brings U.S. K­12 educators and polar researchers together through an innovative teacher research experience model. Participating teachers spend 3-6 weeks in the field with research teams conducting surveys and collecting data on various aspects of polar science. During their experience, teachers become research team members filling a variety of roles on the team. They also fulfill a unique role of public outreach officer, conducting live presentations about their field site and research as well as journaling, answering questions, and posting photos. Working with OIB has opened up the nature of science for the participating teachers. In developing the long-term relationship with OIB teams, teachers can now share (1) the diversity of training, backgrounds, and interests of OIB scientists, (2) identify the linkages between Greenlandic culture and community and cryospheric science and evidence of climate change, (3) network with Danish and Greenlandic educators on the mission (4) gain access to the full spectrum of a science project - development, implementation, analysis, networking, and dissemination of information. All aspects help these teachers become champions of NASA science and educational leaders in their communities. Evaluation data shows that PolarTREC has clearly achieved it goals with the OIB partnership and suggests that linking teachers and researchers can have the potential to transform the nature of science education. By giving teachers the content knowledge, pedagogical tools, confidence, understanding of science in the broader society, and experiences with scientific inquiry, participating teachers are using authentic scientific research in their

  13. Interação planta-inseto: Aspectos biológicos e ecológicos do mutualismo Cecropia-Azteca

    Directory of Open Access Journals (Sweden)

    2015-08-01

    Abstract. A well-known association is the mutualism between plants is between plant species of the genus Cecropia and ants, mostly belonging to the genus Azteca. In this association, the ants nest in domatia present in the hollow trunk of this myrmecophytes and feed on food bodies provided by the plant, known as mullerian bodies. In return, the ants protect the host plant against herbivore attacks and invasion by vines, and nourish it through waste laid in the trunk. However, the effectiveness of this association may vary with several factors, such as the associated ant species and the habitat type of the myrmecophyte. About 10% of Cecropia species lost their attractive characteristics, such as species living in high altitude and inhabit islands. Aspects like associated ant richness and molecular studies show that the colonization of these plants by ants occurred several times and independently by different genera. The selection pressure exerted by some species of ants may have been one of the decisive factors for the development of attractive traits for ants in Cecropia. With the evolution of these features ants might become an effective partner of the plant, facilitating the co-evolution of specific interactions.

  14. Newborn screening for severe combined immunodeficiency using a novel and simplified method to measure T-cell excision circles (TREC).

    Science.gov (United States)

    Tagliaferri, Laura; Kunz, Joachim B; Happich, Margit; Esposito, Susanna; Bruckner, Thomas; Hübschmann, Daniel; Okun, Jürgen G; Hoffmann, Georg F; Schulz, Ansgar; Kappe, Judit; Speckmann, Carsten; Muckenthaler, Martina U; Kulozik, Andreas E

    2017-02-01

    The prognosis of children with severe combined immunodeficiency (SCID) depends on a presymptomatic diagnosis and early treatment before complications occur. We established and tested a simplified, practical and economic newborn screening method based on the quantification of T-cell receptor excision circles (TRECs) on dried blood spots (DBSs) through qPCR. Our method was validated by the analysis of 11 positive controls, which all showed an absence of TRECs, thus yielding a sensitivity of 100%. Further, we analyzed 6034 anonymized newborns of whom 6031 (99,95%) showed a normal TREC qPCR with a median of 600 estimated TREC copies/1.6mm punch. The test showed a recall-rate of 0.05%. We present a highly sensitive, specific and time- and cost-effective method of TREC quantification, which is suitable for SCID newborn screening. In comparison to established methods, our test requires only 25% of the input material, doesn't require DNA purification and significantly reduces time and cost requirement. Copyright © 2016 Elsevier Inc. All rights reserved.

  15. Clinical trial of Cecropia obtusifolia and Marrubium vulgare leaf extracts on blood glucose and serum lipids in type 2 diabetics.

    Science.gov (United States)

    Herrera-Arellano, A; Aguilar-Santamaría, L; García-Hernández, B; Nicasio-Torres, P; Tortoriello, J

    2004-11-01

    Cecropia obtusifolia and Marrubium vulgare have been widely used in Mexican traditional medicine for the control of type 2 diabetes. In order to evaluate the clinical effect produced by the aqueous extract from these species on type 2 non-controlled diabetes mellitus, a total of 43 outpatients were included. Based on the European NIDDM (policy group) criteria, only patients with poor response to the conventional treatment were selected. All patients maintained their medical treatment and also received a prepared infusion of the dry leaves of the plant treatment for 21 days. In a double-blind manner, the patients were randomly grouped as follows: 22 patients were treated with C. obtusifolia and 21 with M. vulgare. The fasting blood glucose values were reduced by 15.25% on patients treated with C. obtusifolia, while cholesterol and triglycerides were decreased by 14.62% and 42.0%, respectively (ANOVA pvulgare, the plasma glucose level was reduced by 0.64% and cholesterol and triglycerides by 4.16% and 5.78%, respectively. When the results were compared between groups, significant differences in glucose and cholesterol diminution were found. The obtained results showed that the infusion prepared with the leaves of C. obtusifolia (containing 2.99+/-0.14mg of chlorogenic acid/g of dried plant) produced beneficial effects on carbohydrate and lipid metabolisms when it was administered as an adjunct on patients with type 2 diabetes with poor response to conventional medical treatment.

  16. PolarTREC-Teachers and Researchers Exploring and Collaborating: Science Education from the Poles to the World

    Science.gov (United States)

    Warnick, W. K.; Breen, K.; Warburton, J.; Fischer, K.; Wiggins, H.; Owens, R.; Polly, B.; Wade, B.; Buxbaum, T.

    2007-12-01

    PolarTREC-Teachers and Researchers Exploring and Collaborating is a three-year (2007-2009) teacher professional development program celebrating the International Polar Year (IPY) that advances polar science education by bringing K-12 educators and polar researchers together in hands-on field experiences in the Arctic and Antarctic. Currently in its second year, the program fosters the integration of research and education to produce a legacy of long-term teacher-researcher collaborations, improved teacher content knowledge through experiences in scientific inquiry, and broad public interest and engagement in polar science. Through PolarTREC, over 40 U.S. teachers will spend two to six weeks in the Arctic or Antarctic, working closely with researchers in the field as an integral part of the science team. Research projects focus on a wide range of IPY science themed topics such as sea-ice dynamics, terrestrial ecology, marine biology, atmospheric chemistry, and long-term climate change. While in the field, teachers and researchers will communicate extensively with their colleagues, communities, and hundreds of students of all ages across the globe, using a variety of tools including satellite phones, online journals, podcasts and interactive "Live from IPY" calls and web-based seminars. The online outreach elements of the project convey these experiences to a broad audience far beyond the classrooms of the PolarTREC teachers. In addition to field research experiences, PolarTREC will support teacher professional development and a sustained community of teachers, scientists, and the public through workshops, Internet seminars, an e-mail listserve, and teacher peer groups. To learn more about PolarTREC visit the website at: http://www.polartrec.com or contact info@polartrec.com or 907-474-1600. PolarTREC is funded by NSF and managed by the Arctic Research Consortium of the US (ARCUS).

  17. Improving Geoscience Education through the PolarTREC Teacher Research Experience Model (Invited)

    Science.gov (United States)

    Warburton, J.; Timm, K.; Larson, A. M.

    2010-12-01

    Teacher Research Experiences (TRE’s) are not new. For more than a decade, the National Science Foundation (NSF) as well as other federal agencies have been funding programs that place teachers with researchers in efforts to invigorate science education by bringing educators and researchers together through hands-on experiences. Many of the TRE’s are successful in providing a hands-on field experience for the teachers and researchers however many of the programs lack the resources to continue the collaborations and support the growing network of teachers that have had these field experiences. In 2007, NSF provided funding for PolarTREC—Teachers and Researchers Exploring and Collaborating, a program of the Arctic Research Consortium of the U.S. (ARCUS). PolarTREC is a TRE where K-12 teachers participate in polar field research, working closely with scientists as a pathway to improving science education. In just three years, it has become a successful TRE. What makes PolarTREC different than other the teacher research experience programs and how can others benefit from what we have learned? During this presentation, we will share data collected through the program evaluation and on how PolarTREC contributes to the discipline of Science, Technology, Engineering, and Mathematics (STEM) education and pedagogy through a model program conceived and organized according to current best practices, such as pre-research training, mentoring, support for classroom transfer, and long-term access to resources and support. Data shows that PolarTREC’s comprehensive program activities have many positive impacts on educators and their ability to teach science concepts and improve their teaching methods. Additionally, K-12 students polled in interest surveys showed significant changes in key areas including amount of time spent in school exploring research activities, importance of understanding science for future work, importance of understanding the polar regions as a person

  18. The effect of symbiotic ant colonies on plant growth: a test using an Azteca-Cecropia system.

    Directory of Open Access Journals (Sweden)

    Karla N Oliveira

    Full Text Available In studies of ant-plant mutualisms, the role that ants play in increasing the growth rates of their plant partners is potentially a key beneficial service. In the field, we measured the growth of Cecropia glaziovii saplings and compared individuals that were naturally colonized by Azteca muelleri ants with uncolonized plants in different seasons (wet and dry. We also measured light availability as well as attributes that could be influenced by the presence of Azteca colonies, such as herbivory, leaf nutrients (total nitrogen and δ(15N, and investments in defense (total phenolics and leaf mass per area. We found that colonized plants grew faster than uncolonized plants and experienced a lower level of herbivory in both the wet and dry seasons. Colonized plants had higher nitrogen content than uncolonized plants, although the δ(15N, light environment, total phenolics and leaf mass per area, did not differ between colonized and uncolonized plants. Since colonized and uncolonized plants did not differ in the direct defenses that we evaluated, yet herbivory was lower in colonized plants, we conclude that biotic defenses were the most effective protection against herbivores in our system. This result supports the hypothesis that protection provided by ants is an important factor promoting plant growth. Since C. glaziovii is widely distributed among a variety of forests and ecotones, and since we demonstrated a strong relationship with their ant partners, this system can be useful for comparative studies of ant-plant interactions in different habitats. Also, given this study was carried out near the transition to the subtropics, these results help generalize the geographic distribution of this mutualism and may shed light on the persistence of the interactions in the face of climate change.

  19. Mining Tasks from the Web Anchor Text Graph: MSR Notebook Paper for the TREC 2015 Tasks Track

    Science.gov (United States)

    2015-11-20

    Mining Tasks from the Web Anchor Text Graph: MSR Notebook Paper for the TREC 2015 Tasks Track Paul N. Bennett Microsoft Research Redmond, USA pauben...investigated the effectiveness of mining session co-occurrence data. For a search engine log, session bound- aries can be defined in the typical way but to

  20. Cecropia peltata l.: Estudios farmacognósticos y de la composición de ácidos grasos libres

    Directory of Open Access Journals (Sweden)

    Abel A Pardo Concepción

    2000-08-01

    Full Text Available Se inició el estudio de la yagruma (Cecropia peltata L. de uso medicinal en Cuba, con la descripción de los índices farmacognósticos mínimos necesarios para establecer la calidad de las hojas de la planta como droga, así como el estudio de la fracción de desengrase de donde se cristaliza una mezcla de 11 ácidos grasos metilados en forma libre, los cuales se caracterizan mediante cromatografía gaseosa acoplada a masas. El 50 % de estos ácidos son insaturados, lo cual puede favorecer el fundamento del uso de la planta popularmente con fines antiasmáticos.The study of yagruma (Cecropia peltata L. of medicinal use in Cuba was started with the description of the minimum pharmacognostic indexes necessary to establish the quality of the leaves of the plant as a drug, as well as the study of the scouring fraction from where a mix of 11 freely methylated fatty acids is crystallized. These acids are characterized by gas chromatography matched to masses. 50% of these acids are unsaturated, which may favor the popular use of the plant with antiasthmatic ends.

  1. Tissue culture of Cecropia glaziovii Sneth (urticaceae: vegetative micropropagation and plant regeneration from callus Cultura de tecidos de Cecropia glaziovii Sneth (Urticaceae: micropropagação vegetativa e regeneração de plantas via calos

    Directory of Open Access Journals (Sweden)

    Marcos Nopper Alves

    2010-10-01

    Full Text Available Cecropia glaziovii is a tree with used in Brazilian popular medicine. Methods allowing the clonal propagation of this species are of great interest for superior genotype multiplication and perpetuation. For this reason, we examined the effect of different culture media and different types of explants on adventitious shoot regeneration from callus and buds of C. glaziovii. Leaves, petioles and stipules obtained from aseptically grown seedlings or from pre-sterilized plants were used to initiate cultures. Adventitious shoot regeneration was achieved when apical and axillary buds were inoculated on gelled Murashige & Skoog (MS medium supplemented with 6-benzylaminopurine alone (BAP (1.0, 5.0 or 10.0 mg L-1 or combined with -naphthalene acetic acid (NAA (1.0 or 2.0 mg L-1, after 40 days of culture. Best callus production was obtained after 30 days of petioles' culture on gelled MS medium with 2,4 dichlorophenoxyacetic acid (2,4-D (5.0 mg L-1 combined with BAP (1.0 mg L-1. Successful shoot regeneration from callus was achieved when MS medium supplemented with zeatin (ZEA (0.1 mg L-1 alone or combined with 2,4-D (1.0 or 5.0 mg L-1 was inoculated with friable callus obtained from petioles. All shoots were rooted by inoculation on MS medium supplemented with indole-3-acetic acid (IAA (1.0 mg L-1. Rooted plants transferred to potting soil were successfully established. All in vitro regenerated plantlets showed to be normal, without morphological variations, being also identical to the source plant. Our study has shown that C. glaziovii can be propagated by tissue culture methods, allowing large scale multiplication of superior plants for pharmacological purposes.Cecropia glaziovii é uma planta lenhosa, popularmente usada no Brasil como medicinal. Métodos que visem a sua propagação clonal podem ser de grande utilidade na preservação de seus genótipos de elite. Foram examinados efeitos de diferentes reguladores de crescimento e explantes na forma

  2. Avaliação do potencial de utilização da madeira de Schizolobium amazonicum "Paricá" e Cecropia hololeuca "Embaúba" para produção de painéis aglomerados Evaluation of potential use of the wood of Schizolobium amazonicum "Paricá" and Cecropia hololeuca "Embaúba" to particleboard manufacture

    Directory of Open Access Journals (Sweden)

    Setsuo Iwakiri

    2010-01-01

    Full Text Available Esta pesquisa teve por objetivo avaliar o potencial de utilização de madeira de Schizolobium amazonicum (Paricá e Cecropia hololeuca (Embaúba para produção de painéis aglomerados. Foram produzidos painéis experimentais com densidade nominal de 0,70 g/cm³, utilizando a resina uréia-formaldeído e partículas de madeira de Paricá e Embaúba, e mistura destas, em proporções de 75, 50 e 25%. A madeira de Pinus taeda foi utilizada como testemunha. Os painéis foram prensados com pressão específica de 40 kgf/cm², temperatura de 160ºC e tempo de prensagem de 8 minutos. Os resultados das avaliações de propriedades de absorção de água, inchamento em espessura, ligação interna, módulo de elasticidade e módulo de ruptura, indicaram que as madeiras de Schizolobium amazonicum (Paricá e Cecropia hololeuca (Embaúba são tecnicamente viáveis para produção de painéis aglomerados.This research was developed to evaluate the potential use of the woods Schizolobium amazonicum (Paricá and Cecropia hololeuca (Embaúba for manufacturing particleboard. Were made panels with the densities of 0.70 g/cm³, using mixtures of urea-formaldehyde resin and wood particles of Paricá and Embaúba, in proportions of 75, 50 and 25%. The Pinus taeda wood was used as the reference. The panels were pressed at the temperature of 160ºC, pressure of 40 kgf/cm², for 8 minutes. The evaluations of the properties of water absorption, thickness swelling, internal bond, modulus of elasticity and modulus of ruptures, showed that the woods of Schizolobium amazonicum (Paricá e Cecropia hololeuca (Embaúba are technically feasible for particleboard manufacture.

  3. Abnormal TREC-Based Newborn Screening Test in a Premature Neonate with Massive Perivillous Fibrin Deposition of the Placenta

    Directory of Open Access Journals (Sweden)

    Stefan Kostadinov

    2016-01-01

    Full Text Available Severe combined immunodeficiency (SCID, a primary immunodeficiency arising from variable defects in lymphocyte development and survival, is characterized by significant deficiency of thymus derived (T- lymphocytes and variable defects in the B-lymphocyte population. Newborn screening for SCID is based on detection of low numbers of T-cell receptor excision circles (TRECs by real time quantitative PCR (RT-qPCR. This screening allows for early identification of individuals with SCID and other disorders characterized by T-lymphopenia. Higher rates of abnormal screens are commonly seen in premature and critically ill neonates, often representing false positives. It is possible that many abnormal screens seen in these populations are result of conditions that are characterized by systemic inflammation or stress, possibly in the context of stress-induced thymic involution. We present a case of a male infant delivered at 27 weeks, 6 days of gestation, with severe intrauterine growth restriction who had an abnormal TREC screen and a massive perivillous fibrin deposition (MPFD of the placenta. This association has not been reported previously. We are raising the awareness to the fact that conditions, such as MPFD, that can create adverse intrauterine environment are capable of causing severe stress-induced thymic involution of the fetus which can present with abnormal TREC results on newborn screening.

  4. Potencial alelopático de espécies nativas na germinação e crescimento inicial de Lactuca sativa L. (Asteraceae Allelopathic potential of native species in Lactuca sativa L. (Asteraceae germination and initial growth

    Directory of Open Access Journals (Sweden)

    Fabiana Maraschin-Silva

    2006-03-01

    Full Text Available A alelopatia caracteriza-se pelos efeitos danosos ou benéficos sobre o desenvolvimento da vegetação, causados por substâncias químicas produzidas e liberadas para o ambiente por uma planta. Com o objetivo de avaliar o potencial alelopático de espécies brasileiras, foram testados extratos foliares de Cecropia pachystachya Trec. (Urticaceae, Peltophorum dubium (Spreng. Taub. (Fabaceae, Psychotria leiocarpa Cham. & Schltdl (Rubiaceae, Sapium glandulatum (Vell. Pax (Euphorbiaceae e Sorocea bonplandii (Baill. Burg., Lanj. & Boer (Moraceae, utilizando-se bioensaios de germinação e crescimento e alface (Lactuca sativa L. como planta alvo. Nesses bioensaios, foram usados extratos foliares aquosos nas concentrações de 2 e 4%, preparados por maceração estática com água fria e quente. Os extratos das cinco espécies causaram atraso na germinação dos aquênios da alface, bem como efeitos tóxicos no crescimento das plântulas, com redução e enfraquecimento das raízes. Os resultados obtidos mostraram a presença de substâncias químicas inibidoras nos extratos, revelando potencial alelopático para as cinco espécies avaliadas.Allelopathy is characterized by harmful or beneficial effects on vegetation development, caused by chemical substances produced and released into the environment by the plant. Aiming to assess the allelopathic potential of Brazilian species, aqueous leaf extracts of Cecropia pachystachya Trec. (Urticaceae, Peltophorum dubium (Spreng. Taub. (Fabaceae, Psychotria leiocarpa Cham. & Schltdl (Rubiaceae, Sapium glandulatum (Vell. Pax (Euphorbiaceae, and Sorocea bonplandii (Baill. Burger, Lanj. & Boer (Moraceae were tested on lettuce using germination and growth bioassays. In these bioassays, aqueous leaf extracts were used at concentrations of 2 and 4%, prepared by static maceration with cold and hot water. The five species extracts delayed lettuce germination and produced toxic effects on seedling growth, with root

  5. Bringing Antarctic Weddell seals to the classroom through PolarTREC

    Science.gov (United States)

    Eilers, A. A.

    2017-12-01

    PolarTREC (Teachers and Researchers Exploring and Collaborating) is an NSF funded professional development opportunity in which K-12 teachers and informal educators participated in hands-on field research experiences in the Polar Regions. The program goal is to invigorate polar science education and understanding by bringing together educators and polar researchers. This unique opportunity for educators has two main components: a 4-6 week field experience and a classroom/community connection piece. In preparation for these experiences, museum educator Alex Eilers and science team lead Dr. Jennifer Burns planned, developed and executed extensive outreach efforts for both students and the community to highlight the Weddell seal research project during the 2012, 2014 and 2016 seasons. The following outreach activities summarize the team's most successful attempts at engaging schoolchildren, teachers and the public, creating a broader impact of the Weddell seal scientific project. On-line Daily journal entries were uploaded to the PolarTREC website encouraging an active interaction between the science team and participants. A Polar Connect event offered participants a real-time, interactive internet presentation with the team. Schools A multitude of on-site presentations were made in classrooms, at teacher workshops and faculty meetings. Two 45 minute labs were developed for students visiting the museum, Animals of the Antarctic and Journey to the Poles, the latter is now included in our ongoing program repertoire. Two travelling kits, Extreme Cold Weather Gear and The Weddell Seal, were developed by museum staff and continue to circulate through schools. A multi-lesson educational module was developed by museum staff to bridge the gap between the scientific research conducted in the field and students in grades 3-8. It contains curriculum-based lessons, field data and strategic methods to assist students in analyzing the data. Community Community-wide interest

  6. TREC 2010 legal track: method and results of the ELK collaboration

    Energy Technology Data Exchange (ETDEWEB)

    Spearing, Shelly [Los Alamos National Laboratory; Roman, Jorge [Los Alamos National Laboratory; Mc Kay, Bain [KAYVIUM; Lindquist, Eric [EWA-IIT

    2010-10-25

    The ELK team ([E]WA-IIT, [L]os Alamos National laboratory (LANL), and [K]ayvium Corporation (ELK)) used the legal Track task 302 as an opportunity to compare and integrate advanced semantic-automation strategies. The team members believe that enabling parties to discover, consume, analyze, and make decisions in a noisy and information-overloaded environment requires new tools. Together, as well as independently, they are actively developing these tools and view the TREC exercise as an opportunity to test, compare, and complement tools and approaches. Our collaboration is new to TREC, brought together by a shared interest in document relevance, concept-in-context identification and annotation, and the recognition that words out-of-context do not a match make. The team's intent was to lay the foundation for automating the mining and analysis of large volumes of electronic information by litigants and their lawyers, not only in the context of document discovery, but also to support litigation strategy, motion practice, deposition, trial tactics, etc. The premise was that a Subject Matter Expert- (SME-) built model can be automatically mapped onto various search engines for document retrieval, organization, relevance scoring, analysis and decision support. In the end, we ran nearly a dozen models, mostly, but not exclusively, with Kayvium Corporation's knowledge automation technology. The Sal Database Search Engine we used had a bug in its proximity feature, requiring that we develop a workaround. While the work-around was successful, it left us with insufficient time to converge the models to achieve expected quality. However, with optimized proximity processing in place, we would be able to run the model many more times, and believe repeatable quality would be a matter of working through a few requests to get the approach right. We believe that with more time, the results we would achieve might point towards a new way of processing documents for litigation

  7. Exploring the link between innate immune activation and thymic function by measuring sCD14 and TRECs in HIV patients living in Belgium.

    Directory of Open Access Journals (Sweden)

    Adrien De Voeght

    Full Text Available Microbial translocation is now viewed as a central event in the pathogenesis of chronic inflammation during HIV infection. Thymic function failure is another crucial factor involved in HIV disease progression. The goal of this study was to explore the hypothesis of potential links between microbial translocation and thymic function in HIV-1 patients living in Belgium. The extent of microbial translocation was assessed through the measurement of soluble CD14 (sCD14. T-cell receptor excision circles (sjTRECs and dβTRECs were used as a measure of thymic function. Data were collected from 75 HIV-infected patients. Simple and complex linear regressions were done to analyze the link between these two processes. We found a statistically relevant negative correlation between thymopoiesis (sjTREC and sCD14 level (p = 0.004. These results suggest a link between thymic function failure, microbial translocation and innate immune activation.

  8. Estabelecimento de Espécies Florestais Nativas Via Semeadura Direta no Rio Piauitinga - Sergipe

    Directory of Open Access Journals (Sweden)

    Janisson Batista de Jesus

    2017-04-01

    Full Text Available RESUMO A técnica de semeadura direta vem se destacando nos projetos de recuperação florestal pela redução de custos na implantação e tem sido cada vez mais utilizada. Este trabalho foi realizado com o objetivo de avaliar a emergência, sobrevivência e estabelecimento de espécies florestais nativas, por meio de sementes em áreas de mata ciliar no Rio Piauitinga, município de Lagarto, SE. As espécies utilizadas foram Libidibia ferrea var. leiostachya (Benth. L. P. Queiroz, Cassia grandis L. f., Cecropia pachystachya Trec., Enterolobium contortisiliquum (Vell. Morong e Guazuma ulmifolia Lam. O experimento em campo foi implantado em Delineamento em Blocos Casualizados (DBC com quatro repetições, em esquema fatorial, testando-se as cinco espécies com e sem tratamento para superação de dormência. A semeadura direta mostrou-se uma técnica viável para a área de estudo apenas para as espécies L. ferrea var. leiostachya, E. contortisiliquum e Cassia grandis, utilizando-se sementes com e sem dormência.

  9. DETERMINATION OF REFERENCE VALUES FOR TREC AND KREC IN DRY BLOOD SPOTS OF NEWBORNS FROM DIFFERENT GESTATION AGES IN SVERDLOVSK REGION

    Directory of Open Access Journals (Sweden)

    S. S. Deryabina

    2018-01-01

    Full Text Available As a preparatory stage for implementation of genetic testing for severe combined immunodeficiency under a neonatal screening program, a study was performed in Sverdlovsk Region which concerned quantitative determination of T and B cell neogenesis markers (TREC and KREC, respectively in blood of conditionally healthy newborns. Archived samples of dry blood spots collected in test-forms for routine neonatal screening were used as biological material for the study of full-term 26 girls and 26 boys who did not exhibit serious illnesses during first year of their life. In addition, we investigated potential effects of foetal gestational age upon the number of TREC and KREC in preterm infants. Blood samples from 55 preterm infants (23 to 36 gestational weeks were also examined. It was shown that the levels of TREC and KREC increased sequentially with the increased gestation terms, but the quantitative changes of markers showed different dynamics. In this respect, the recommended terms of blood sample collection for SCID screening is entirely consistent with timing of blood sampling for routine newborn screening. An alternative result was obtained with a complete absence of TREC or KREC in blood sample of a newborn, irrespectively of prematurity degree (at valid copy numbers of a control gene which should serve as an indication for immediate consulting of the child by immunologist and in-depth immunological examination, because it may be a first prognostic sign of a fatal disease. In order to obtain correct cut-off levels for TREC/KREC, additional studies are needed on a larger sample of newborns (1.000 to 5.000, followed by validation of the obtained reference boundaries in studies involving patients with different forms of primary immunodeficiencies. 

  10. El enojo en madres y padres de hijas adolescentes: propuesta de orientación desde la TREC y la inteligencia emocional / The anger in parents of teenage daughters: propose of guidance since the TREC and emotional intelligence

    Directory of Open Access Journals (Sweden)

    Murillo Aguilar, Osvaldo

    2008-08-01

    Full Text Available Resumen: Este artículo, basado en la tesis de grado denominada “Expresión del Enojo en Madres y Padres de Hijas Adolescentes: Propuesta de Orientación desde el Enfoque de la TREC”, realizada por Jessie Arroyo Zúñiga y Osvaldo Murillo Aguilar, para optar por el grado de licenciatura en Orientación en el año 2008, ofrece desde esta disciplina, una integración entre la teoría de la Inteligencia Emocional y el enfoque de la Terapia Racional Emotivo – Conductual (TREC, para comprender y abordar la expresión del enojo en estas madres y padres de hijas adolescentes. Por ello, como recomendación, se presenta una propuesta de Orientación que pretende fortalecer los vínculos de las madres y padres con sus hijas adolescentes, por medio de un proceso que propicie formas de expresión emocionalmente saludables del enojo, basado en la integración de la teoría de la inteligencia emocional y el enfoque de la TREC. Para la elaboración del presente trabajo se establecieron los siguientes objetivos: 1. Analizar las formas en las que expresan el enojo las madres y los padres de familia del Liceo María Auxiliadora.2. Elaborar estrategias de Orientación dirigidas a madres y padres de hijas adolescentes que promuevan una expresión saludable del enojo. La metodología se estableció bajo la perspectiva cualitativa, que permitió la comprensión de las experiencias de las madres y los padres, sus emociones, pensamientos y conductas. La principal técnica de recolección de información fueron los grupos focales, y se analizó a partir de la organización y codificación de datos, por medio de categorías de análisis.Abstract: This article, based on the thesis entitled "Expression of Anger in Mothers and Fathers of Daughters Teens: proposed of Guidance since the TREC" performed by Jessie Arroyo Zúñiga and Osvaldo Murillo Aguilar, to graduate in Guidance in the 2008; offers from this discipline, an integration between the theory of Emotional

  11. Review of Theoretical Prediction Models for Organic Extract Metabolites, Effect of Drying Temperature on Smooth Muscle Relaxing Activity Induced by Organic Extracts Specially Cecropia Obtusifolia Portal and Web Server Predictors of Drug-Protein Interaction.

    Science.gov (United States)

    Aguirre-Crespo, Francisco; García-Mera, Xerardo; Guillén-Poot, Mónica Anahi; May-Díaz, Héctor Fernado; Tun-Suárez, Adrián; Aguirre-Crespo, A; Hernández-Rodríguez, J; Vergara-Galicia, Jorge; Rodríguez-López, V; Prado-Prado, Francisco J

    2015-02-19

    Cecropia obtusifolia bertol is medicinal specie used in the treatment of diabetes mellitus and hypertension and it has scientific studies that support the traditional use. However, it is required to understand the influence of drying temperature on the yield and pharmacological activity. Drying rate, extraction efficiency, changes in the UV-Vis spectrum and estimating chlorophylls were stimulated with the increasing temperature. Finally, relaxant activity of vascular smooth muscle is increased by 70ºC and reducing ability by the method of CARF increases with temperature. Analytical studies are required to identify changes in the metabolic content and those that ensure the safety and efficacy for human consumption. In this sense, bioinformatic studies may be helpful. Studies such as QSAR can help us to study these metabolites derived from natural products. MIND-BETS model and NL MIND-BETS model to predict DPIs was introduced using MARCH-INSIDE (MI) software to calculate structural parameters for drugs and enzymes respectively. We firstly revised the state-of-art on the design with review of previous works with hypertension activity based on theoretical studies. A study, evaluating the effect of drying temperature of leaves of C. obtusifolia on the relaxing of vascular smooth muscle, antioxidant activity and the presence of chlorophylls, with a focus on Cecropia metabolites. Last, we carried out QSAR studies using MIND-BEST and NL MIND-BEST web servers in order to understand the essential metabolites structural requirement for binding with receptors for FDA proteins.

  12. Barriers to retrieving patient information from electronic health record data: failure analysis from the TREC Medical Records Track.

    Science.gov (United States)

    Edinger, Tracy; Cohen, Aaron M; Bedrick, Steven; Ambert, Kyle; Hersh, William

    2012-01-01

    Secondary use of electronic health record (EHR) data relies on the ability to retrieve accurate and complete information about desired patient populations. The Text Retrieval Conference (TREC) 2011 Medical Records Track was a challenge evaluation allowing comparison of systems and algorithms to retrieve patients eligible for clinical studies from a corpus of de-identified medical records, grouped by patient visit. Participants retrieved cohorts of patients relevant to 35 different clinical topics, and visits were judged for relevance to each topic. This study identified the most common barriers to identifying specific clinic populations in the test collection. Using the runs from track participants and judged visits, we analyzed the five non-relevant visits most often retrieved and the five relevant visits most often overlooked. Categories were developed iteratively to group the reasons for incorrect retrieval for each of the 35 topics. Reasons fell into nine categories for non-relevant visits and five categories for relevant visits. Non-relevant visits were most often retrieved because they contained a non-relevant reference to the topic terms. Relevant visits were most often infrequently retrieved because they used a synonym for a topic term. This failure analysis provides insight into areas for future improvement in EHR-based retrieval with techniques such as more widespread and complete use of standardized terminology in retrieval and data entry systems.

  13. DEVELOPMENT OF REAL-TIME MULTIPLEX PCR FOR THE QUANTITATIVE DETERMINATION OF TREC'S AND KREC'S IN WHOLE BLOOD AND IN DRIED BLOOD SPOTS

    Directory of Open Access Journals (Sweden)

    M. A. Gordukova

    2015-01-01

    Full Text Available Primary immunodeficiencies (PID such as severe combined immunodeficiency (SCID and X-linked agammaglobulinemia are characterized by the lack of functional Tand B-cells, respectively. Without early diagnosis and prompt treatment children with PID suffer from severe infectious diseases, leading to their death or disability. Our purpose was developing of simple, inexpensive, high throughput technique based on the quantitative determination of TREC and KREC molecules by real-time PCR, and its validation in a group of children with a verified diagnosis of SCID and X-linked agammaglobulinemia.In this study, we developed and validated multiplex real-time PCR for the TREC’s and KREC’s quantitative analysis. We have shown that linear range of Ct changes depending on the concentrations of targets with a correlation coefficient R2 not worse than 0.98 was observed at concentrations from 109 to 5 × 104 copies per ml. The lowest amount of targets reliably detected in a reaction volume was 10 TREC’s copies, 5 KREC ‘s copies and 5 copies of internal control (IL17RA. We determined the age-depended reference values of TRECs and KRECs in whole blood in 29 boys and 27 girls with normal immunological parameters. The normal cut-offs for TRECs and KRECs were defined in dry blood spots depending on the method of extraction.The proposed method showed 100% diagnostic sensitivity and specificity in the studied group. The method can be proposed as a screening tool for the diagnosis of SCID and X-linked agammaglobulinemia both in whole blood and in the dry blood spots. The further investigation is required with larger number of samples. 

  14. T-cell Receptor Excision Circles (TREC) in CD4+ and CD8+ T-cell Subpopulations in Atopic Dermatitis and Psoriasis Show Major Differences in the Emission of Recent Thymic Emigrants

    DEFF Research Database (Denmark)

    Just, Helle; Deleuran, Mette; Vestergaard, Christian

    2008-01-01

    dermatitis showed signs of altered thymus function, as they had a significantly greater variation in TREC content measured over time than healthy controls, especially within the CD8+ T-cell subpopulation. Because both atopic derma nottitis and psoriasis patients have an increased number of T...

  15. A preliminary study measuring the number of T-cell receptor-rearrangement excision circles (TRECs) in peripheral blood T-cell populations of A-bomb survivors and control populations

    International Nuclear Information System (INIS)

    Kubo, Yoshiko; Yamaoka, Mika; Kusunoki, Yoichiro

    2006-01-01

    More than a half century after damage of the immune systems by the radiation from A-bomb, we can still observe significant decreases in the percentages of naieve CD4 and CD8 T cells among the survivors. To investigate whether the observed decreases in the naieve T-cell populations may have resulted from reduction in thymic T-cell production ability of survivors, we established a real-time polymerase chain reaction (PCR) method to examine the number of T-cell receptor-rearrangement excision circles (TRECs) in peripheral blood CD4 and CD8 T-cell populations. The real-time PCR quantitatively detected TREC sequences with a good reproducibility in human laboratory controls. In the 445 survivors so far been examined, multiple regression analysis indicated that the number of TRECs in the CD4 T-cell fraction was significantly higher in females than in males and decreased significantly with age in both males and females. This analysis also suggested a possible dose-dependent decrease in the number of TRECs in the CD4 T-cell fraction of the survivors who were less than 20 years of age at the time of bombing (p=0.09). A similar statistically significant trend for gender difference or age was observed in the CD8 T-cell fraction of the survivors. However, there was no effect of radiation exposure on the number of TRECs in the CD8-T cell fraction. The results indicate the possibility that A-bomb radiation exposure may have induced a long-term impairment in thymic CD4 T-cell production. Further investigations in a larger study population are necessary to test this hypothesis. (author)

  16. ECOLOGICAL FACTORS ASSOCIATED WITH THE ESTABLISHMENT OF RUSTIC SPECIES IN DISTURBED ECOSYSTEMS IN THE ATLANTIC FOREST, PIRAÍ, RIO DE JANEIRO STATE – BRAZIL

    Directory of Open Access Journals (Sweden)

    Hiram Feijó Baylão Junior

    2013-08-01

    Full Text Available http://dx.doi.org/10.5902/1980509810542 Disturbed ecosystems do not present original floristic composition. Their soils are depleted, shallow, stony, with low infiltration and present erosion with different levels of Geodynamics. The region has areas of pasture with sparse herbaceous vegetation which is weakened in every rain and fire, covering less ground. The individuals that colonized and settled in these environments were considered rustic species. This study raised and identified by census, the rustic species and their structure in the most degraded part (lower third of the watershed of Cacaria’s river at the base of the Serra do Mar, Piraí, Rio de Janeiro state, and evaluated the influence of ecological exposure, slope, elevation, topography and rock outcrops in the establishment and growth of these species. For the vegetation survey it was conducted census in an area of 22 hectares, where it was measured, geo-referenced and identified all spontaneous tree species that were isolated in a pasture area. Ecological factors exposure, elevation and slope were determined with a compass, altimeter and clinometer, respectively. We identified 131 individuals, representing 14 species, grouped into nine families. Tabernaemontana laeta Mart., Sparattosperma leucanthum (Vell. Schum., Machaerium hirtum (Vell. Stellfeld, Tabebuia chrysotricha (Mart. ex DC. Stan., Cecropia pachystachya Trec., Peltophorum dubium (Spreng. Taub., Guarea guidonia (L. Sleumer, Acacia polyphylla DC. and Psidium guajava L.were present in portions of the slope with exposure to the north, with altitudes from 60m to 80m and with slope strongly corrugated (20-45%, indicating a preference of these species for microhabitats with those characteristics. 

  17. Inquery and TREC-9

    National Research Council Canada - National Science Library

    Allan, James; Connell, Margaret E; Croft, W. B; Feng, Fang-Fang; Fisher, David; Li, Xiaoyan

    2000-01-01

    ...: the Inquery search engine, query processing, and a query expansion technique known as LCA. All three tracks used Inquery as the search engine, sometimes for training, and always for generating the final ranked lists for the test...

  18. Relación empírica entre la Terapia Racional Emotivo-Conductual (TREC) de Ellis y la Terapia Cognitiva (TC) de Beck en una muestra costarricense

    OpenAIRE

    Cabezas Pizarro, Hannia; Lega, Leonor I.

    2012-01-01

    En este estudio se explora una posible relación empírica entre la terapia racional emotivoconductual (TREC) de Ellis y la terapia cognitiva (TC) de Beck, dos de los modelos más conspicuos en el campo de la psicoterapia cognitiva actual. Si bien este modelo utiliza el término “cognitivo” en forma tal que se encuentra asociado con el afecto, la fisiología y la conducta (Dobson, 1986), sostiene que las perturbaciones emocionales, en esencia, son causadas por el proceso cognitivo del individuo. E...

  19. A new species of Cecropia (Moraceae)

    NARCIS (Netherlands)

    Berg, C.C.

    1972-01-01

    Arbor 25-30 m alta. Ramuli foliosi hispidi, hispiduli, vel scabri. Lamina fere ad petiolum 15-partita; segmenta oblanceolata, 7-25 cm longa, 2-4.5 cm lata, plerumque obtusa, pagina superiore scabridula, inferiore arachnoideo-tomentosa, ad venas albo-puberula vel -hirtella; venae secundariae circ.

  20. Levantamento etnobotânico de plantas utilizadas como anti-hiperlipidêmicas e anorexígenas pela população de Nova Xavantina-MT, Brasil

    Directory of Open Access Journals (Sweden)

    Marcondes Alves B. da Silva

    Full Text Available O presente trabalho verificou a utilização de plantas medicinais encontradas no Cerrado mato-grossense para o tratamento de hiperlipidemias e obesidade. Entrevistas com 180 pessoas acima de 50 anos foram realizadas em Nova Xavantina-MT. O questionário abordou nome popular, parte utilizada, forma de preparo e uso das espécies citadas, além de informações gerais sobre o uso de plantas. As dez plantas mais citadas foram coletadas, identificadas e estudadas por meio de uma revisão bibliográfica. A maioria dos entrevistados (95,6% declarou utilizar plantas medicinais regularmente, sendo que 71,5% deles herdaram o conhecimento sobre plantas dos pais e avós e 94,20% relataram aconselhar o uso aos mais jovens. Além disso, 93,6% atestaram que as plantas são mais eficazes que os medicamentos de farmácia e 57% consideraram forte o efeito das mesmas, ou seja, sempre resolvem o problema de saúde. Quanto aos efeitos adversos, 95,9% disseram nunca ter sentido após o uso de plantas. Dos entrevistados, 56,7% conheciam ou já haviam utilizado plantas medicinais no tratamento de hiperlipidemias e obesidade, sendo citadas 54 espécies medicinais diferentes pertencentes a 53 gêneros e 38 famílias, com destaque para Fabaceae (13%. As dez plantas mais citadas foram: guatambu (Aspidosperma tomentosum Mart., quina-do-cerrado (Strychnos pseudoquina St. Hil., ipê-roxo [Tabebuia impetiginosa (Mart. Ex DC. Standl], embaúba (Cecropia pachystachya Trec., calunga (Simaba sp., pata-de-vaca [Bauhinia rufa (Bong. Steud.], mangaba (Hancornia speciosa Gomez, batata-de-tiú [Jatropha elliptica (Pohl. Muell. Arg.], folha-de-carne (Casearia sylvestris Sw. e manacá (Spiranthera odoratissima A. St.-Hil.. A folha foi a parte mais utilizada (46% e o preparo das plantas ocorre principalmente por meio de infusão citado por 36,5% dos entrevistados. Apesar do uso popular destas plantas no combate as hiperlipidemias e obesidade, há necessidade de estudos fitoquímicos e

  1. Slocum-TREC Thermal Glider

    Science.gov (United States)

    Huntsberger, Terry; Jones, Jack A.; Valdez, Thomas; Stirbl, Rob

    2012-01-01

    JPL is now teaming with Teledyne-Webb-Research to produce the first thermal glider that uses PCM for direct buoyancy control (not electronic pumps) and to produce all other required electricity. TWR has increased electrical production total efficiency from 0.45 to 0.61. JPL performed over 6000 cycles (2.4 years) of accelerated life testing of a piston accumulator. Design, fabrication, and testing will be performed in 2012, with deployment by Rutgers University in late 2012. The proposed goal of the ocean endurance tests was 3 months, but will be extended to at last 1 year. The piston accumulator was cycled over 6,000 times in a three-month period in order to simulate continuous glider life of about 2.4 years, The life test data suggests that we might accumulate roughly 0.5 cc of gas in the oil bladders for each cycle. PCM canisters will be fabricated with a compressed aluminum foam core, 7.5% foam selected (< 42 minutes to freeze anticipated) An Axi 5345/18 3-Phase AC alternator selected for power generation, 61% energy storage efficiency A 4-Cell A123 Energy Storage Systems battery selected for energy storage, buss voltage 14.4 to 12.5 V (13.2 V nominal) Glider deployment expected in late 2012

  2. Slocum-TREC Thermal Glider

    Science.gov (United States)

    Huntsberger, Terry; Jones, Jack A.; Valdez, Thomas; Stirbl, Rob

    2012-01-01

    JPL is now teaming with Teledyne-Webb-Research to produce the first thermal glider that uses PCM for direct buoyancy control (not electronic pumps) and to produce all other required electricity. TWR has increased electrical production total efficiency from 0.45 to 0.61. JPL performed over 6000 cycles (2.4 years) of accelerated life testing of a piston accumulator. Design, fabrication, and testing will be performed in 2012, with deployment by Rutgers University in late 2012. The proposed goal of the ocean endurance tests was 3 months, but will be extended to at last 1 year. The piston accumulator was cycled over 6,000 times in a three-month period in order to simulate continuous glider life of about 2.4 years, The life test data suggests that we might accumulate roughly 0.5 cc of gas in the oil bladders for each cycle. PCM canisters will be fabricated with a compressed aluminum foam core, 7.5% foam selected (Glider deployment expected in late 2012

  3. TREC Dynamic Domain: Polar Science

    Science.gov (United States)

    2015-11-20

    similarity. However, not all teams that submitted web crawls to this dataset applied their jaccard- similarity algorithms . 4.2 Data Format ...analysis. These algorithms were focused then on allowing better answers to the below representative science queries of our Polar data: 1. What...

  4. Avaliação do efeito mutagênico do extrato hidroalcoólico bruto, por meio de bioensaios in vivo e prospecção fitoquímica de Cecropia glaziovii Sneth (embaúba, Cecropiaceae

    Directory of Open Access Journals (Sweden)

    Victor S. Stange

    Full Text Available O gênero Cecropia é conhecido popularmente por "embaúba" e apresenta várias espécies medicinais, sendo que estudos com a espécie C. glaziovii Sneth indicam que o extrato aquoso apresenta efeitos broncodilatador, anti-hipertensivo e antidepressivo, provavelmente, atribuídos às catequinas, procianidinas e flavonóides. O presente estudo objetivou avaliar os potenciais efeitos tóxico, citotóxicos, clastogênicos e aneugênicos do extrato bruto hidroalcoólico de folhas de C. glaziovii, por meio da dose letal média (DL50, da análise de micronúcleo em células de medula óssea de roedores e do teste com Allium cepa e realizar a prospecção fitoquímica. Os resultados demonstraram que as concentrações testadas não causaram toxicidade aguda, nem apresentaram atividade clastogênica e aneugênica, sugerindo que o extrato de C. glaziovii não interferem na divisão celular. A prospecção fitoquímica indicou a presença de taninos, flavonóides, fenóis, antraquinonas, cumarinas, catequinas, proteínas, açúcares redutores, depsídeos/depsidonas e triterpenos. Mesmo assim, esses resultados não prescrevem o consumo terapêutico da espécie, sem continuidade da sua avaliação e do cumprimento de todas as etapas pré-clínicas e clínicas.

  5. Triagem fitoquímica e avaliação das atividades trombolítica e citotóxica de Cecropia hololeuca Miq. (Urticaceae, Lippia alba (Mill. N.E.Br. ex P. Wilson (Verbenaceae e Zanthoxylum rhoifolium Lam (Rutaceae

    Directory of Open Access Journals (Sweden)

    João Victor Dutra GOMES1 ; Rafael Destefani FAITANIN

    2016-03-01

    Full Text Available Cecropia hololeuca, Lippia alba, e Zanthoxylum rhoifolium são espécies vegetais de ocorrência natural no Brasil, características de regiões de Mata Atlântica e, dentro de suas finalidades medicinais, estão incluídas ação anti-hipertensiva, digestiva e no tratamento de malária. Neste estudo, foram avaliados o perfil fitoquímico e as atividades citotóxica e trombolítica do extrato etanólico das folhas destas espécies vegetais. O perfil químico dos extratos foi obtido por meio de ensaios fitoquímicos clássicos, a fim de identificar as classes químicas presentes. A toxicidade preliminar foi avaliada frente Artemia salina e a atividade trombolítica foi determinada in vitro a partir da lise de coágulo de sangue humano. Os testes fitoquímicos indicaram a presença de alcaloides e flavonoides nos três extratos investigados. Saponinas, triterpenos e naftoquinonas foram detectados apenas em C. hololeuca. Essa não demonstrou toxicidade frente Artemia salina (DL50 >1000 ppm, enquanto Z. rhoifolium apresentou DL50 igual a 719,44 ppm e L. alba <250 ppm, o que indica atenção quanto à segurança no uso desta planta medicinal. A atividade trombolítica de L. alba e C. hololeuca foi de 6,43 ±2,08 e 9,64 ±1,83 %, respectivamente, mostrando baixa atividade. Por sua vez, Z. rhoifolium alcançou lise de 24,71 ±10,52 %, indicando promissora atividade (p <0,001. A atividade trombolítica de Z. rhoifolium justifica novos estudos, a fim de investigar os componentes responsáveis pela atividade. Perante a literatura, este é o primeiro relato da avaliação da atividade trombolítica destas espécies vegetais. Os resultados encontrados neste trabalho contribuem para o conhecimento químico-biológico das respectivas espécies.

  6. Overview of the TREC 2009 Web Track

    Science.gov (United States)

    2009-11-01

    volvo </query...description> I’m looking for information on Volvo cars and trucks. </description> <subtopic number=ŕ" type="nav"> I’m looking for Volvo’s homepage...subtopic> <subtopic number=Ŗ" type="inf"> Find reviews of the Volvo XC90 SUV. </subtopic> <subtopic number=ŗ" type="inf"> Where can I find Volvo

  7. PKUTM at TREC 2010 Blog Track

    Science.gov (United States)

    2010-11-01

    task, we constructed our own sentiment lexicon based on the following lexicons. SetntiWordNet SentiWordNet [2] is a lexical resource for opinion...mining. SentiWordNet assigns to each synset of WordNet three sentiment scores: positivity, negativity, objectivity. We can get the opinion score of...Shanshan Huang for proofreading the paper. References [1] Z. Dong, HowNet. http://www.HowNet.org [2] A. Esuli and F. Sebastiani. SentiWordNet : A

  8. DCU at the TREC 2008 Blog Track

    Science.gov (United States)

    2008-11-01

    sentiment ori- entation of a blog entry by aggregating the sentiment scores for its consituent words in a sentiment lexicon, SentiWordNet . • A Surface...lexicon SentiWordNet [4]. SentiWordNet is a lexicon which assigns negative and positive scores to each sense of each synset in WordNet based on a semi...success [10], [12]. For our experiments, we considered the positive SentiWordNet score for a word w to be the mean of the positive scores for all the

  9. University of Delaware at TREC 2014

    Science.gov (United States)

    2014-11-01

    have dreams at night, and cravings in the day, about the chicken salad sandwich. Also, it is entirely true that one breakfast sandwich can be THAT much...0.565817 0.472367 0.831190 udel itub 0.18607 0.16364 0.534793 0.443358 0.812524 Table 6: Graded relevance measures and diversity measures with Bing

  10. TUW @ TREC Clinical Decision Support Track 2015

    Science.gov (United States)

    2015-11-20

    between 2003 and 2013, and the ShARe/CLEF eHealth Evaluation Lab [15,3,11,12] running since 2013. Here we briefly describe the participation of Vienna...Mart́ınez, G. Zuccon, and J. R. M. Palotti. Overview of the share/clef ehealth evaluation lab 2014. In Information Access Evaluation. Mul- tilinguality...Symposium, IIiX ’14, pages 283–286. ACM, 2014. 11. J. Palotti, G. Zuccon, L. Goeuriot, L. Kelly, A. Hanbury, G. Jones, M. Lupu, and P. Pecina. Clef ehealth

  11. IBM’s PIQUANT in TREC2003

    Science.gov (United States)

    2003-01-01

    La Bomba ,’’ ( the bomb ) for his explosive skiing style DSA P11 work: La Bomba LQA P12 most successful and popular Italian skier ever DSA P11...personal coach SQA star SQA the most famous ski racer of all time DSA P11 vaulting him from seventh to fourth with 1:41.48 DSA P11 born...Alberto Tomba , Italy LQA P2 lawyer SQA job: champion LQA P6 work: Slalom for Peace LQA P12 born: Italy LQA P2 work: the Bomba LQA P12 some World Cup

  12. University of glasgow at TREC 2006

    DEFF Research Database (Denmark)

    Lioma, Christina; Macdonald, C.; Plachouras, V.

    2006-01-01

    -independent evidence, in the form of prior probabilities. In the Enterprise track, we test our new voting model for expert search. Our experiments focus on the need for candidate length normalisation, and on how retrieval performance can be enhanced by applying retrieval techniques to the underlying ranking...

  13. TUW @ TREC Clinical Decision Support Track

    Science.gov (United States)

    2014-11-01

    decided to experiment with different search models and indexing possibilities, trying to build a initial foun- dation for our future participation next...Foundation. The default search model of Lucene is the Vector Space Model ( VSM ), and it was used with the default parameters. As for Run1, six runs were...system. In any case, a detailed investigation of the performance of these two runs need to be carried in the future . Run2 and Run3 were our best runs

  14. Overview of the TREC 2014 Session Track

    Science.gov (United States)

    2014-11-01

    wishes to work on the problem of retrieval over sessions. The experimental design of the track was similar to that of the previous three years [5, 6, 1...TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) University of Delaware,Department of Computer & Information...quitting smoking, second effects of quitting smoking, using hypnosis to quit smoking, using the cold turkey method to quit smoking</desc> </topic

  15. Abundância e frugivoria da quiropterofauna (Mammalia, chiroptera de um fragmento no noroeste do Estado do Paraná, Brasil = Chiropterofauna abundance and frugivory in a forest remnant in northwestern Paraná State, Brazil

    Directory of Open Access Journals (Sweden)

    João Eduardo Cavalcanti Brito

    2010-07-01

    Full Text Available A abundância e a frugivoria de morcegos que compõem a taxocenose em uma área de mata ripária, à margem esquerda do rio Ivaí, foram foco do presente estudo. O Recanto Marista possui 57,6 hectares, dos quais 40,8 são cobertos por Floresta Estacional Semidecidual, situado no município de Doutor Camargo, região Noroeste do Estado do Paraná. Foram realizadas 14 noites de capturas de morcegos de maio de 2007 a janeiro de 2008, com redesneblina (7 x 2,5 m, totalizando 13.475 m² h de esforço amostral, distribuído em 72h de esforço. Foram capturados 193 indivíduos, representantes de dez espécies, pertencentes a duas famílias: Phyllostomidae (Artibeus lituratus, Sturnira lilium, Carollia perspicillata, Artibeus cf. fimbriatus, Artibeus planirotris, Desmodus rotundus e Pygoderma bilabiatum e Vespertilionidae (Myotis nigricans, Eptesicus sp. e Lasiurus blossevillii. Um representante da família Molossidae (Molossus rufus foi encontrado morto no solo. Foram consumidos frutos pertencentes às famílias Moraceae (Ficus guaranitica, Ficus insipida, Ficus sp. e Maclura tinctoria, Solanaceae (Solanum aspero-lanatum e Solanum sp., Piperaceae (Piper aduncum, Piper amalago e Piper sp. e Urticaceae (Cecropia pachystachya e Cecropia sp..This study aims to evaluate the abundance and frugivory of bats from the Recanto Marista, a small riparian forest remnant in the margins of the Ivaí river. The Recanto Marista has 57.6 ha, of which 40.8 ha are covered by semideciduous seasonal forest and is located in the Doutor Camargo municipality. Collections were conducted from May 2007to January 2008 using mist nets (7 x 2.5 m totaling 13,475 m² h and comprising about 72 hours. Ten species were found pertaining to two families, Phyllostomidae (Artibeus lituratus, Sturnira lilium, Carollia perspicillata, Artibeus cf. fimbriatus, Artibeus planirotris, Desmodus rotundus and Pygoderma bilabiatum and Vespertilionidae (Myotis nigricans, Eptesicus sp. and Lasiurus

  16. Abundância e frugivoria da quiropterofauna (Mammalia, chiroptera de um fragmento no noroeste do Estado do Paraná, Brasil - doi: 10.4025/actascibiolsci.v32i3.5351 Chiropterofauna abundance and frugivory in a forest remnant in northwestern Paraná State, Brazil - doi: 10.4025/actascibiolsci.v32i3.5351

    Directory of Open Access Journals (Sweden)

    Janaina Gazarini

    2010-09-01

    Full Text Available A abundância e a frugivoria de morcegos que compõem a taxocenose em uma área de mata ripária, à margem esquerda do rio Ivaí, foram foco do presente estudo. O Recanto Marista possui 57,6 hectares, dos quais 40,8 são cobertos por Floresta Estacional Semidecidual, situado no município de Doutor Camargo, região Noroeste do Estado do Paraná. Foram realizadas 14 noites de capturas de morcegos de maio de 2007 a janeiro de 2008, com redes-neblina (7 x 2,5 m, totalizando 13.475 m² h de esforço amostral, distribuído em 72h de esforço. Foram capturados 193 indivíduos, representantes de dez espécies, pertencentes a duas famílias: Phyllostomidae (Artibeus lituratus, Sturnira lilium, Carollia perspicillata, Artibeus cf. fimbriatus, Artibeus planirotris, Desmodus rotundus e Pygoderma bilabiatum e Vespertilionidae (Myotis nigricans, Eptesicus sp. e Lasiurus blossevillii. Um representante da família Molossidae (Molossus rufus foi encontrado morto no solo. Foram consumidos frutos pertencentes às famílias Moraceae (Ficus guaranitica, Ficus insipida, Ficus sp. e Maclura tinctoria, Solanaceae (Solanum aspero-lanatum e Solanum sp. , Piperaceae (Piper aduncum, Piper amalago e Piper sp. e Urticaceae (Cecropia pachystachya e Cecropia sp..This study aims to evaluate the abundance and frugivory of bats from the Recanto Marista, a small riparian forest remnant in the margins of the Ivaí river. The Recanto Marista has 57.6 ha, of which 40.8 ha are covered by semideciduous seasonal forest and is located in the Doutor Camargo municipality. Collections were conducted from May 2007 to January 2008 using mist nets (7 x 2.5 m totaling 13,475 m² h and comprising about 72 hours. Ten species were found pertaining to two families, Phyllostomidae (Artibeus lituratus, Sturnira lilium, Carollia perspicillata, Artibeus cf. fimbriatus, Artibeus planirotris, Desmodus rotundus and Pygoderma bilabiatum and Vespertilionidae (Myotis nigricans, Eptesicus sp. and Lasiurus

  17. InteraÃÃo do fosfato de rocha, matÃria orgÃnica e microbiota do solo na produÃÃo de mudas de arbÃreas nativas de interesse econÃmico e ambiental no Nordeste brasileiro

    OpenAIRE

    Eudes Pinheiro da Silva

    2013-01-01

    A regeneraÃÃo natural da vegetaÃÃo à o procedimento mais barato para reabilitar Ãreas degradadas, porÃm, à lento. O plantio de mudas de arbÃreas nativas pode ser uma soluÃÃo. Nesse contexto, conduziu-se o presente trabalho em casa de vegetaÃÃo por 120 dias, testando 5 doses de P (0, 75, 150, 300 e 600 mg L-1) com fosfato de rocha natural na colonizaÃÃo por FMA e por rizÃbio nativos, e no desenvolvimento de mudas de embaÃba (Cecropia pachystachya TrÃcul) e de sabià (Mimosa caesalpiniaefolia Be...

  18. Frugivory by phyllostomid bats (Mammalia: Chiroptera) in a restored area in Southeast Brazil

    Science.gov (United States)

    Silveira, Maurício; Trevelin, Leonardo; Port-Carvalho, Marcio; Godoi, Simone; Mandetta, Elizabeth Neuenhaus; Cruz-Neto, Ariovaldo P.

    2011-01-01

    We studied the potential contribution of frugivorous bats to the reestablishment of vegetational diversity in a restored area. We analysed the diets of the bat species and the differences between them in the consumption of fruits of autochtonous and allochthonous species. Planted (autochtonous) species were the basis of diets, especially Solanum mauritianum and Cecropia pachystachya, whereas for allochthonous species we found that Piperaceae to be of particular importance. Carollia perspicillata was the main seed disperser for allochthonous species, and potentially the most important bat in the promotion of vegetation diversity in the study area. Our results suggest that frugivorous bats are especially important in the reestablishment of vegetation in disturbed areas, and that restorarion efforts should focus on the planting of different zoochorous species that would guarantee a high year-round fruit production, thereby facilitating natural plant reestablishment by frugivorous bats in regenerating areas.

  19. WaterlooClarke: TREC 2015 Clinical Decision Support Track

    Science.gov (United States)

    2015-11-20

    infertility treatment and ectopic pregnancy Processed example (filtering + one synonyms+boolean operators): (dysmenorrhea OR men- orrhalgia) AND... medical questions (diagnosis, test and treatment articles). The two different full-text search engines we adopted in order to search over the collection of...Abstract Clinical decision support systems help physicians with finding additional information about a partic- ular medical case. In this paper, we

  20. Overview of the TREC 2009 Chemical IR Track

    Science.gov (United States)

    2009-11-01

    soluble polyvinyl acetal wherein the acetal-group is substutiuted by alkyl - groups only. 12 Diazepam or RN: 439- 14-5 Pharmaceuticals Please identify...all documents on diazepam being used as a muscle relaxant (there are other names see ChemID plus or PubChem) 13 tetrahydrocannabinol as an anti-tumour...chemical company that do custom synthesis for different clients in the pharmaceuticals and fine chemicals communities. One of our customers has asked

  1. UMass at TREC 2002: Cross Language and Novelty Tracks

    National Research Council Canada - National Science Library

    Larkey, Leah S; Allan, James; Connell, Margaret E; Bolivar, Alvaro; Wade, Courtney

    2002-01-01

    .... The cross-language submission was characterized by combination of evidence to merge results from two different retrieval engines and a variety of different resources - stemmers, dictionaries, machine...

  2. Overview of the TREC 2014 Federated Web Search Track

    Science.gov (United States)

    2014-11-01

    Chronicling America News e002 CCSB Academic e101 CNN News e003 CERN Documents Academic e102 Forbes News e004 CiteSeerX Academic e104 JSOnline News e005... Disease Control and Prevention Health e156 Cnet Software e064 Family Practice notebook Health e157 GitHub Software e065 Health Finder Health e158...bluffs 7235 silicone roof coatings 7236 lomustine 7239 roundabout safety 7242 hague convention 7249 largest alligator on record 7250 collagen vascular

  3. Webis at TREC 2014: Web, Session, and Contextual Suggestion Tracks

    Science.gov (United States)

    2014-11-01

    two decimals , since otherwise there are hardly any terms with equal tf (x) or td(x) values. Some axioms employ a similarity measure sim(w1, w2) for two...Our setting of Kemeny rank aggregation can be transformed to such a problem by viewing it as a di- rected weighted graph with the vertex set V = {d1...inconsistent information: Ranking and clustering . Journal of the ACM, 55(5):23:1–23:27, 2008. [2] E. Amigó, J. Gonzalo, and F. Verdejo. A general evaluation

  4. Overview of the TREC 2013 Contextual Suggestion Track

    Science.gov (United States)

    2013-11-01

    once if in the area! I really enjoyed it. URL http://www.elfrethsalley.org • ID 65 Title Red Mango Description Red Mango is committed to providing the...venue categorization, for example “landmark” or “amusement park”, then the system creates a language model for each category. The category-specific... language models are used to perform the retrieval for each individual category mentioned in a user’s profile. Suggestions are personalized by making

  5. NudtMDP at TREC 2015 LiveQA Track

    Science.gov (United States)

    2015-11-20

    that are from real-user. All the testing questions are from Yahoo Answer. YA questions have many question types such as opinion, advice, polls, which...Secondly, all of the questions are from Yahoo Answer questioners. Most ques- tions are asked by spoken language. There exist many oral words and the...in Sept.2. One sys- tem(nudtmdp 2) just use CQAs which include eight community question answer websites such as Yahoo Answer, AnswerBag and Answers as

  6. WaterlooClarke: TREC 2015 LiveQA Track

    Science.gov (United States)

    2015-11-20

    from Yahoo ! An- swers1 – a community question answering website. Each question was broadcasted to all registered systems. The participants had to...were coming from Yahoo ! Answers – a community question answering website. Questions there vary greatly between all topics and question types. Yahoo ...in your opinion? Body: I can’t decide they are all gorgeousss ɛ :) Table 1: Various types of questions asked on Yahoo ! Answers 1). The questions were

  7. ECNU at TREC 2015: LiveQA Track

    Science.gov (United States)

    2015-11-20

    user questions, extracted from the stream of most recent questions submitted on the Yahoo Answers (YA) site that have not yet been answered by humans...extracting answers for real- user questions in real time. Since many questions submitted on these CQA sites like Yahoo Answers, have been asked by...Framework pages on Yahoo Answers as the candidates. Then, we utilize our question selection module to find out the most similar question and choose the best

  8. RMIT at the TREC 2015 LiveQA Track

    Science.gov (United States)

    2015-11-20

    wikiextractor,6 and indexed every Wikipedia page as a document. To index the Yahoo ! Answers CQA data, we processed the collection as follows: rather than just...2000 AQUAINT2 907K 410M Newswire, Oct 2004 - Mar 2006 Wikipedia-EN 4,847K 1,775M Online knowledge base Yahoo ! Answers CQA v1.0 31,972K 1,462M Question...answers converted to documents from the Yahoo ! Answers website. summarization is characterized as a two-way optimization problem, in which coverage

  9. TREC2002 Web, Novelty and Filtering Track Experiments Using PIRCS

    National Research Council Canada - National Science Library

    Kwok, K. L; Deng, P; Dinstl, N; Chan, M

    2006-01-01

    .... The Web track has two tasks: distillation and named-page retrieval. Distillation is a new utility concept for ranking documents, and needs new design on the output document ranked list after an ad-hoc retrieval from the web (.gov) collection...

  10. PRIS at TREC 2010 Blog Track: Faceted Blog Distillation

    Science.gov (United States)

    2010-11-01

    faceted blog distillation system is presented. Finally in Section 4, conclusions and comments on the future work are given. 2 The Faceted Blog... VSM ) to score the blogs [9]. (p(t1|post), p(t2|post), p(t3|post) …p(ti|post)) and (personal(t1), personal(t2), personal(t3) …personal(ti)) can

  11. BUPT_PRIS at TREC 2012 Session Track

    Science.gov (United States)

    2012-11-01

    filter 2. Re-rank by PageRank score 1. Spam ranking filter 2. VSM similarity model RL2 1. User behavior model 2. Spam ranking filter 1. User...behavior model 2. Spam ranking filter 3. Re-rank by PageRank score and indri score 1. User behavior model 2. Spam ranking filter 3. VSM ...use the click data very efficiently. These two methods can improve search performance, but they need to be optimized in the future work. References

  12. CWI at TREC 2012, KBA Track and Session Track

    Science.gov (United States)

    2012-11-01

    epistemic model that accomodates the deterministic information about the interactions and one pure prob- abilistic model. A general case of such a...is: how can we mod- ify existing IR models such as in [3] in order to accomodate a for- malisation of these epistemic states as “observed" (with... accomodate these two interests, we thought of an approach as in Figure 3.1. The model could be anything. We thought of a machine-learned model, string

  13. RUC at TREC 2014: Select Resources Using Topic Models

    Science.gov (United States)

    2014-11-01

    preprocess the data by parsing the pages ( html , txt, doc, xls, ppt, pdf, xml files) into tokens, removing the stopwords listed in the Indri’s...Gravano. Classification-Aware Hidden- Web Text Database Selection. ACM Trans. Inf. Syst. Vol. 26, No. 2, Article 6, April 2008. [8] J. Seo and B. W

  14. FDUMedSearch at TREC 2015 Clinical Decision Support Track

    Science.gov (United States)

    2015-11-20

    been widely used in improving biomedical information retrieval [2-5]. We used the query to obtain the relevant citations in MEDLINE . The MeSH terms...scale MeSH indexing by integrating diverse evidence. Bioinformatics 31(12): 339-347 (2015) [3] Zhu S, Zeng J, Mamitsuka H. Enhancing MEDLINE document...Mamitsuka H, Zhu S. Efficient Semisupervised MEDLINE Document Clustering With MeSH-Semantic and Global-Content Constraints. IEEE T. Cybernetics 43(4

  15. Atigeo at TREC 2014 Clinical Decision Support Task

    Science.gov (United States)

    2014-11-01

    their parent codes before in- dexing them. We conducted similar explorations on the MEDLINE corpus, in which each document is indexed with human...discussed in Section 7.4 that com- bines semantic information and pseudo-relevance feedback, but sadly, that approach also only works for the MEDLINE corpus...done with respect to the MEDLINE corpus, and alt- hough they provide interesting insight to the prob- lem, many of the methods may not be applicable to

  16. CWI at TREC 2012, KBA track and Session Track

    NARCIS (Netherlands)

    S. Araújo (Samur); C. Boscarino (Corrado); G.G. Gebremeskel (Gebre); J. He (Jiyin); A.P. de Vries (Arjen); E.M. Voorhees; L. P. Buckland (Buckland, Lori P.)

    2013-01-01

    htmlabstractWe participated in two tracks: Knowledge Base Acceleration (KBA) Track and Session Track. In the KBA track, we focused on experi- menting with different approaches as it is the first time the track is launched. We experimented with supervised and unsupervised re- trieval models. Our

  17. WHU at TREC KBA Vital Filtering Track 2014

    Science.gov (United States)

    2014-11-01

    view the problem as a classification problem and use Stanford NLP Toolkit to extract necessary information. Various kinds of features are leveraged to...profile of an entity. Our approach is to view the problem as a classification problem and use Stanford NLP Toolkit to extract necessary information

  18. The HLTCOE Approach to the TREC 2012 KBA Track

    Science.gov (United States)

    2012-11-01

    clear whether this method has particular difficulty when two entities share a name. None of the Boris Bere- zovsky ( pianist ) documents were correctly...0.07 0.33 Boris Berezovsky (businessman) 100 0.33 0.27 0.3 0.33 Boris Berezovsky ( pianist ) 950 0 0 0 0.33 Charlie Savage 400 0.61 0.23 0.33 0.44

  19. Nitrogen use strategies of seedlings from neotropical tree species of distinct successional groups.

    Science.gov (United States)

    Oliveira, Halley Caixeta; da Silva, Ligia Maria Inocêncio; de Freitas, Letícia Dias; Debiasi, Tatiane Viegas; Marchiori, Nidia Mara; Aidar, Marcos Pereira Marinho; Bianchini, Edmilson; Pimenta, José Antonio; Stolf-Moreira, Renata

    2017-05-01

    Few studies have analyzed the strategies of neotropical tree seedlings for absorbing, translocating and assimilating the nitrogen. Here, we compared the nitrogen use strategies of seedlings from six tree species that are native to the Brazilian Atlantic Forest and that belong to different successional groups: Trema micrantha, Heliocarpus popayanensis and Cecropia pachystachya (pioneers), Cariniana estrellensis, Eugenia brasiliensis and Guarea kunthiana (non-pioneers). The effects of cultivating seedlings with nitrate or ammonium on the growth, physiology and nitrogen metabolism were analyzed. Nitrate-grown pioneer species had much higher leaf nitrate reductase activity than non-pioneer ones, but non-pioneer seedlings were also able to use nitrate as a nitrogen source. In addition to this remarkable difference between the groups in the capacity for leaf nitrate assimilation, substantial variations in the nitrogen use strategies were observed within the successional classes. Differently from the other non-pioneers, the canopy species C. estrellensis seemed to assimilate nitrate mainly in the leaves. Morphophysiological analyses showed a gradient of ammonium toxicity response, with E. brasiliensis as the most tolerant species, and T. micrantha and H. popayanensis as the most sensitive ones. Guarea kunthiana showed a relatively low tolerance to ammonium and an unusual high translocation of this cation in the xylem sap. In contrast to the other pioneers, C. pachystachya had a high plasticity in the use of nitrogen sources. Overall, these results suggest that nitrogen use strategies of neotropical tree seedlings were not determined solely by their successional position. Copyright © 2017 Elsevier Masson SAS. All rights reserved.

  20. Abundance and frugivory of the Toco toucan (Ramphastos toco) in a gallery forest in Brazil's southern Pantanal.

    Science.gov (United States)

    Ragusa-Netto, J

    2006-02-01

    Unlike other toucan species, the Toco toucan (Ramphastos toco)--the largest Ramphastidae--usually inhabits dry semi-open areas. This conspicuous canopy frugivore uses a large home range that includes a variety of vegetation types, among which gallery forests are widely cited as important to this species. However, the factors relating to the occurrence of Toco toucans in such habitats are unclear. I studied the abundance of Toco toucans as well as the availability of fleshy fruit in a gallery forest in the southern Pantanal (sub-region of Miranda, Brazil), in order to assess the relationship between these parameters. Also, I examined toucan foraging activity to analyze its relationship with both toucan abundance and fruit availability. The presence of the Toco toucan was more common in the gallery forest from the middle to the end of the dry season and during the middle of the wet season. Toucans foraged for fleshy fruits, mainly Genipa americana, Ficus luschnatiana, and Cecropia pachystachya fruits, feeding mostly on G. americana (by far the favorite food resource) and F. luschnatiana fruits during the dry season, while C. pachystachya fruits were important in the wet season. Toco toucans foraged particularly heavily (> 80% of foraging activity) on G. americana fruits during the latter part of the dry season, when fleshy fruit availability declined sharply. Toco toucan abundance in the gallery forest was associated with the availability of the most commonly consumed fleshy fruits, and also with its foraging activity. This finding suggests that the Toco toucan moved to the gallery forest periodically in response to the availability of abundant food resources, especially the G. americana fruits widely available and exploited during the severely dry season. Therefore, these fruits potentially contribute to Toco toucan persistence in the South Pantanal during the harshest period of the year.

  1. Abundance and frugivory of the toco toucan (Ramphastos toco in a gallery forest in Brazil's Southern Pantanal

    Directory of Open Access Journals (Sweden)

    J. Ragusa-Netto

    Full Text Available Unlike other toucan species, the Toco toucan (Ramphastos toco - the largest Ramphastidae - usually inhabits dry semi-open areas. This conspicuous canopy frugivore uses a large home range that includes a variety of vegetation types, among which gallery forests are widely cited as important to this species. However, the factors relating to the occurrence of Toco toucans in such habitats are unclear. I studied the abundance of Toco toucans as well as the availability of fleshy fruit in a gallery forest in the southern Pantanal (sub-region of Miranda, Brazil, in order to assess the relationship between these parameters. Also, I examined toucan foraging activity to analyze its relationship with both toucan abundance and fruit availability. The presence of the Toco toucan was more common in the gallery forest from the middle to the end of the dry season and during the middle of the wet season. Toucans foraged for fleshy fruits, mainly Genipa americana, Ficus luschnatiana, and Cecropia pachystachya fruits, feeding mostly on G. americana (by far the favorite food resource and F. luschnatiana fruits during the dry season, while C. pachystachya fruits were important in the wet season. Toco toucans foraged particularly heavily (> 80% of foraging activity on G. americana fruits during the latter part of the dry season, when fleshy fruit availability declined sharply. Toco toucan abundance in the gallery forest was associated with the availability of the most commonly consumed fleshy fruits, and also with its foraging activity. This finding suggests that the Toco toucan moved to the gallery forest periodically in response to the availability of abundant food resources, especially the G. americana fruits widely available and exploited during the severely dry season. Therefore, these fruits potentially contribute to Toco toucan persistence in the South Pantanal during the harshest period of the year.

  2. Comparison of the diet of Alouatta caraya (Primates: Atelidae between a riparian island and mainland on the Upper Parana River, southern Brazil Comparação da dieta de Alouatta caraya (Primates: Atelidae em mata ciliar insular e continental na região do Alto rio Paraná, Sul do Brasil

    Directory of Open Access Journals (Sweden)

    Gabriela Ludwig

    2008-09-01

    Full Text Available Howler monkeys (Alouatta Lacèpéde, 1799 are folivores-frugivores with flexible diets depending on conditions. Here, we compare the diets of Alouatta caraya (Humboldt, 1812 in two riparian forests (island and mainland, in Porto Rico region, Upper Paraná River, Southern Brazil. Howlers were followed from October 2004 to September 2005 in the riparian forest of a 1,050 ha island and in the continuous riparian forest on the mainland (left bank of the river. The "scan sampling" method with instantaneous samples every 15 minutes was used. Besides vines, diet breadth was similar: 17 species consumed on the island versus 16 species on the mainland. Both consumed leaves followed by fruits more than any other food type (leaves: island - 65%, mainland - 49%, fruits: island - 24%, mainland - 46%. Even though the plant Cecropia pachystachya Trécul is less abundant in the mainland it was the item most consumed in both locations all year long, which suggests its importance for the howlers. Diet also varied both seasonally and between the island and mainland, apparently following changes in local abundance of each item and due to plant phenologies.Os bugios (Alouatta Lacèpéde, 1799 são primatas folívoros-frugívoros que podem adaptar suas dietas dependendo das condições do ambiente. O presente trabalho compara a dieta de grupos de Alouatta caraya (Humboldt, 1812 presentes em matas ciliares estruturalmente diferentes (ilha e continente, na região de Porto Rico, Alto rio Paraná, sul do Brasil. Os bugios-pretos foram seguidos de outubro de 2004 a setembro de 2005 em mata ciliar de uma ilha fluvial de 1050 ha e em mata ciliar contínua da margem esquerda do rio. Foi utilizado o método "scan sampling" em amostragens instantâneas com intervalos de 15 minutos. Além das lianas, 17 espécies foram consumidas na ilha versus 16 espécies no continente. Ambos os grupos consumiram mais folhas seguido de frutos do que qualquer outro tipo de alimento (folhas

  3. Antioxidant properties of species from the Brazilian cerrado by different assays

    Directory of Open Access Journals (Sweden)

    K.S. Farias

    2013-01-01

    Full Text Available The purpose of this study was to screen the antioxidant activity of medicinal plant extracts from the Brazilian cerrado, through other methods than the total phenolic content and its correlation with the antioxidant activity. Ethanolic extracts of ten species were evaluated through three antioxidant assays, in vitro, including 2,2-diphenyl-1-picrylhydrazyl (DPPH, total antioxidant activity and reducing power; and by using the Folin-Ciocalteu method the total phenolic content was determined. Ethanolic extracts of Stryphnodendron obovatum, Cecropia pachystachya and Duguetia furfuraceae showed strong antioxidant activity (IC50<5 µg mL-1 in the DPPH free radical scavenging assay; the species Vernonia phosphorea, Hymenaea stignocarpa and Jacaranda ulei may also be highlighted. These results were confirmed in the assays of total antioxidant capacity and reducing power. The extracts of S. obovatum and V. phosphorea showed an abundant phenolic content; therefore, the phenolic content may play a role in the antioxidant activity. These two species, traditionally used in Brazil, showed great power in these assay systems and may be a promising source for the development of natural antioxidants and future candidates for phytochemical and pharmacological studies in related diseases.

  4. Dieta de morcegos filostomídeos (Mammalia, Chiroptera, Phyllostomidae em fragmento urbano do Instituto São Vicente, Campo Grande, Mato Grosso do Sul

    Directory of Open Access Journals (Sweden)

    Mariana Pires Veiga Martins

    2014-01-01

    Full Text Available Os morcegos (Chiroptera, devido à sua diversidade e abundância exercem um importante papel ecológico para o ecossistema. O objetivo deste trabalho foi reportar a dieta das espécies de morcegos frugívoros capturados nos fragmentos do Instituto São Vicente, zona urbana do município de Campo Grande, MS. As coletas ocorreram entre setembro de 2011 e Junho de 2012, sendo realizadas com o auxílio de redes-de-neblina. Foram realizadas 154 capturas, com ocorrência de 10 espécies representantes de três famílias, sendo predominantes as espécies frugívoras. Dentre as capturas foram obtidas 41 amostras fecais, onde se verificou a presença de polpa, vestígios de artrópodes e sementes. O recurso mais utilizado por quirópteros foram plantas pioneiras, constatado através do predomínio de sementes da espécie Cecropia pachystachya, consumida em maior intensidade por Artibeus lituratus. Os resultados ressaltam a importância destes animais no ambiente, em especial no processo de regeneração dessas áreas através da dispersão de sementes.

  5. Flowers, fruits, and the abundance of the yellow-chevroned parakeet (Brotogeris chiriri) at a gallery forest in the South Pantanal (Brazil).

    Science.gov (United States)

    Ragusa-Netto, J

    2004-11-01

    Parakeets usually forage for massive and ephemeral plant resources at forest canopies. Fruit pulp is widely cited as a major food resource for these birds, which often eat seeds and nectar. In this study, I assessed flower and fruit production at a gallery forest in the Pantanal flood plain (Brazil) in order to evaluate the relationship between food resource production and abundance of a common parakeet, Brotogeris chiriri. Also, I evaluated the relationship between food resource production and foraging activity. Parakeet abundance varied markedly along the year, coinciding with massive episodes of flower and fleshy fruit availability. Inga vera nectar, intensely used during the latter part of dry season, was by far the most exploited food item by parakeets when they were very abundant. The nectar comprised 34% of the parakeets' diet (N = 131 feeding records) at the gallery forest, while fleshy fruits made up the rest. Parakeets principally exploited fruits of Cecropia pachystachya and Ficus luschnathiana, besides palm fruits and Inga vera arils. The consistent relationship between foraging activity and parakeet abundance, as well as the coincidence between fluctuations of these parameters and availability of major food resources, suggests that food availability mostly influenced B. chiriri occurrence in the gallery forest. Furthermore, I found no evidence for gallery forest use for roosting and/or breeding, in spite of the fact that such factors usually influence local parakeet abundance.

  6. Análise fitossociológica de um remanescente de vegetação na microbacia do Córrego Criminoso (Bacia do Rio Taquari, Coxim, MS, Brasil: subsídios para a recomposição da vegetação Phytosociological analysis of a vegetation remnant in the Córrego Criminoso Basin (Taquari River Basin, Coxim District, Mato Grosso do Sul, Brazil: data for vegetation recovery studies

    Directory of Open Access Journals (Sweden)

    Adriana Maria Güntzel

    2011-09-01

    Full Text Available O objetivo deste estudo foi realizar a análise florística e fitossociológica preliminar em um remanescente de vegetação na área de entorno do Córrego Criminoso, visando subsidiar futuros projetos de recomposição da vegetação. A área total do remanescente foi determinada com o auxílio de GPS e dos programas Pathfinder e Autocad. Amostragens de indivíduos com CAP maior ou igual a 20 cm foram realizadas em 20 parcelas de 300 m² distribuídas na área. Foram encontradas 26 famílias botânicas contendo 36 gêneros e 49 espécies. A família Leguminosae foi a mais rica em espécies, seguida da família Annonaceae. A espécie Xylopia aromatica foi a mais freqüente, apresentando valores de IVI e IVC de 99,77 e 85,73, respectivamente. Observou-se que mais de 50% das espécies presentes na área são pioneiras ou secundárias, sendo cinco consideradas típicas de matas ciliares: Tapirira guianenses, Cecropia pachystachya, Terminalia argentea, Ocotea pulchellae e Luehea grandiflora. O remanescente de vegetação do entorno do Córrego Criminoso encontra-se fortemente degradado, necessitando de ações de manejo específicos nos fragmentos vegetados e nas áreas destituídas de vegetação, cujas recomendações são propostas.The aim of this study was to complete a preliminary, floristic, phytosociological analyses of a vegetation remnant in the Criminoso Stream Basin, in order to provide data for future projects focusing on vegetation recovery. The total area of the remnant was determined using a GPS and the software Pathfinder and Autocad. Samples of individuals larger or equal to 20 cm CBH were made in 20 quadrats that were 300 m². Thirty-six genera and 49 species, within 26 botanical families, were found. The family Leguminosae was the richest in species, followed by the Annonaceae. Xylopia aromatica was the most frequent species, presenting values of IVI and IVC of 99.77 and 85.73, respectively. More than 50% of the species present

  7. Estrutura fitossociológia de um fragmento natural de floresta inundável em área de orizicultura irrigada, município de Lagoa da Confusão, Tocantins Phytosociologial structure of a natural fragment of floodplain forest in area of irrigated rice cultivation, municipal district of Lagoa da Confusão, Tocantins, Brazil

    Directory of Open Access Journals (Sweden)

    Elizabeth Rodrigues Brito

    2006-10-01

    Full Text Available Os fragmentos naturais de florestas inundáveis conhecidos como ipucas localizam-se na planície do Araguaia, sob a forma de depressões naturais, que no Estado do Tocantins estão situados em áreas de planícies de inundação, que favorece seu alagamento e, conseqüentemente, o maior tempo de retenção da água em épocas de elevada precipitação. O presente estudo foi desenvolvido na fazenda Lago Verde, Município de Lagoa da Confusão, Tocantins, situado entre as coordenadas UTM: 643586 e 644060 leste e 8792795 e 8799167 norte. O objetivo do trabalho foi caracterizar a estrutura de um fragmento de floresta inundável de aproximadamente um hectare, inserido em área de orizicultura irrigada. Para o levantamento fitossociológico, foram amostrados todos os indivíduos arbustivo-arbóreos com perímetro a 1,30 m do solo (PAP > 15 cm. Ao todo, foram encontrados 807 indivíduos, 35 famílias e 70 espécies. As espécies com maior VC, em ordem decrescente, foram Hirtella racemosa Lam., Qualea multiflora Mart. e Cecropia pachystachya Trécul. As famílias mais ricas em espécies foram Fabaceae (9, Vochysiaceae (6, Annonaceae e Malvaceae (4. O índice de diversidade de Shannon (H' foi de 3,44. A distribuição de classes de diâmetro apresentou curva na forma de "J" invertido, estando a maioria dos indivíduos na primeira classe.The natural fragments of floodplain forests known as "ipucas" are located in the Araguaia plain, in form of natural depressions, which are located in areas of floodplains in the State of Tocantins, favoring its flooding and, consequently, the largest period of water retention during periods of high precipitation. The present study was developed at Lagoa Verde farm, municipal district of Lagoa da Confusão, Tocantins between the coordinates UTM: 643586 and 644060 east and 8792795 and 8799167 north. The objective of the work was to characterize the structure of a floodplain forest fragment of approximately one-hectare area

  8. Feeding ecology of the Green-cheeked parakeet (Pyrrhura molinae in dry forests in western Brazil Ecologia alimentar da Tiriba-de-cara-suja (Pyrrhura molinae em matas secas do oeste brasileiro

    Directory of Open Access Journals (Sweden)

    J. Ragusa-Netto

    2007-05-01

    Full Text Available The genus Pyrrhura includes small to medium-sized parakeets, which inhabit both low and dry alongside tall rainforests, mainly in South America. Pyrrhura molinae is still common, year round, in the markedly seasonal forests of western Brazil. This parakeet, as well as most Neotropical parrots, continues to be poorly understood. Hence, in the present study I examined their foraging ecology both in a highly deciduous and in a semi-deciduous forest in western Brazil. In addition, I assessed the relationship between food resource production (flowers and fruits, and the diet of this parakeet. Pyrrhura molinae exhibited a flexible diet consisting of 16 tree species, from which it consumed flowers (three species, seeds (three species, fruit pulp or aril (four species, and both pulp and seeds (six species. Parakeets consumed a wide array of fleshy fruits in the semi-deciduous forest, especially Cecropia pachystachya catkins. Conversely, in the highly deciduous forest they extensively foraged for figs (70% of the diet, in addition to nectar and seeds from dry fruits. Ficus calyptroceras, besides being abundant, bore fruits year round, and was substantially used by parakeets every month. Potentially, by exploiting a diverse set of plant food resources, and particularly due to the substantial use of figs, asynchronously produced, Pyrrhura molinae persists during the long dry season in the markedly seasonal forests of western Brazil.O gênero Pyrrhura é constituido de pequenos periquitos comuns tanto em matas secas quanto úmidas, sobretudo da América do Sul. Pyrrhura molinae ocorre durante o ano todo em florestas altamente sazonais do oeste brasileiro. Essa espécie, bem como a maioria dos psitacídeo, permanece pouco conhecida. Portanto, nesse estudo, foi examinada a ecologia alimentar de P. molinae em dois tipos de florestas secas (altamente decídua e semidecídua, do oeste brasileiro, bem como as relações entre a produção de flores frutos e a

  9. Flowers, fruits, and the abundance of the yellow-chevroned parakeet (Brotogeris chiriri at a gallery forest in the South Pantanal (Brazil Flores, frutos e abundância do periquito-de-asa-amarela (Brotogeris chiriri em uma mata ciliar do Pantanal Sul (Brasil

    Directory of Open Access Journals (Sweden)

    J. Ragusa-Netto

    2004-11-01

    Full Text Available Parakeets usually forage for massive and ephemeral plant resources at forest canopies. Fruit pulp is widely cited as a major food resource for these birds, which often eat seeds and nectar. In this study, I assessed flower and fruit production at a gallery forest in the Pantanal flood plain (Brazil in order to evaluate the relationship between food resource production and abundance of a common parakeet, Brotogeris chiriri. Also, I evaluated the relationship between food resource production and foraging activity. Parakeet abundance varied markedly along the year, coinciding with massive episodes of flower and fleshy fruit availability. Inga vera nectar, intensely used during the latter part of dry season, was by far the most exploited food item by parakeets when they were very abundant. The nectar comprised 34% of the parakeets' diet (N = 131 feeding records at the gallery forest, while fleshy fruits made up the rest. Parakeets principally exploited fruits of Cecropia pachystachya and Ficus luschnathiana, besides palm fruits and Inga vera arils. The consistent relationship between foraging activity and parakeet abundance, as well as the coincidence between fluctuations of these parameters and availability of major food resources, suggests that food availability mostly influenced B. chiriri occurrence in the gallery forest. Furthermore, I found no evidence for gallery forest use for roosting and/or breeding, in spite of the fact that such factors usually influence local parakeet abundance.Periquitos normalmente exploram recursos massivos e efêmeros no dossel das florestas tropicais. Dentre os itens alimentares mais utilizados está a polpa de frutos, embora sementes e néctar também sejam consumidos. Neste estudo, foi avaliada a produção de flores e frutos em uma mata ciliar do Pantanal (Brasil e sua relação com a abundância do periquito Brotogeris chiriri. Além disso, avaliaram-se as relações entre a produção de flores e frutos e o

  10. THUIR at TREC 2009 Web Track: Finding Relevant and Diverse Results for Large Scale Web Search

    Science.gov (United States)

    2009-11-01

    Porn words‟ filtering is also one of the anti-spam techniques in real world search engines. A list of porn words was found from the internet [2...When the numbers of the porn words in the page is larger than α, then the page is taken as the spam. In our experiments, the threshold is set to 16

  11. KLE at TREC 2008 Blog Track: Blog Post and Feed Retrieval

    Science.gov (United States)

    2008-11-01

    for defining the subjectivity of a word - SentiWordNet , automat- ically learned model from the review corpus. 4.2.1 SentiWordNet SentiWordNet (Esuli...and Sebastiani, 2006) is a lexical resource for opinion mining. SentiWordNet assigns to each synset of WordNet three sentiment scores: positivity...opinionated. 4.2.2 Corpus-Based Lexicon In addition to SentiWordNet , we use Amazon’s product review corpus and product specification cor- pus to create

  12. Opinions in Federated Search: University of Lugano at TREC 2014 Federated Web Search Track

    Science.gov (United States)

    2014-11-01

    lexicon-based approach that counts the number of SentiWordNet terms appearing in documents of each resource [2]. For the last step, i.e., combining...SCS). According to SCS, we first need to calculate the sentiment of each document. We do this using a lexicon- based approach and the SentiWordNet ...is the relative frequency of term t in document d (see Equation (4)) and sent(t) is the dictionary sentiment of t as given by SentiWordNet . The

  13. Building an Entity-Centric Stream Filtering Test Collection for TREC 2012

    Science.gov (United States)

    2012-11-01

    consecutive hours from October 2011 through April 2012. It contains over 400M documents, which we augmented with named entity classification...CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING...than IR. We also constructed an entirely new stream corpus spanning 4,973 consecutive hours from October 2011 through April 2012. It contains over 400M

  14. Laval University and Lakehead University Experiments at TREC 2015 Contextual Suggestion Track

    Science.gov (United States)

    2015-11-20

    are downloaded synchronously into two data- bases MySQL and ElasticSearch. We query Elas- ticSearch for candidate suggestions while get train- ing data...from MySQL for MySQL has a better API for data retrieving though ElasticSearch also has all the data we need. ` Then a trained regressor will... MySQL and Elas- ticSearch as the crawler push data to the two sim- ultaneously. ` V. ONLINE RANKING MODEL A. Modeling of User Profile While

  15. A Hybrid Method for Opinion Finding Task (KUNLP at TREC 2008 Blog Track)

    Science.gov (United States)

    2008-11-01

    deployed this idea by using Clusty search en- gine2. Clusty is a text clustering search engine al- lows grouping search results into folder topics. Em...pirically, we issue an original query to Clusty and take the titles of top n clusters3 as expanded terms. Pseudo-relevance feedback: The intuition of...contain terms which are highly related to the topic. For simply examining this method, we se- 2http://clusty.com 3In Clusty , clusters are sorted by

  16. UMass at TREC WEB 2014: Entity Query Feature Expansion using Knowledge Base Links

    Science.gov (United States)

    2014-11-01

    task on the category A subset and demonstrate the benefit of entity-centric approaches even for non-entity queries like “dark chocolate health benefits...category A subset and demonstrate the benefit of entity-centric approaches even for non-entity queries like ???dark chocolate health benefits???. 15

  17. CRP Henri Tudor at TREC 2014: Combining Search Results for Clinical Decision Support

    Science.gov (United States)

    2014-11-01

    their pairwise semantic similarity. Acknowledgments This work has been done in the context of the GECAMed2 R&D project (“ Gestion de Cabinets Médicaux...SANTEC, Public Research Centre Henri Tudor, 6 avenue des Hauts-Fourneaux, Esch-sur-Alzette, Luxembourg 1 Introduction This paper presents the first...currently valid OMB control number. 1. REPORT DATE NOV 2014 2. REPORT TYPE 3. DATES COVERED 00-00-2014 to 00-00-2014 4. TITLE AND SUBTITLE CRP

  18. TREC Microblog 2012 Track: Real-Time Algorithm for Microblog Ranking Systems

    Science.gov (United States)

    2012-11-01

    Mining Text Data. 2012. [5] D. Feltoni. Twittersa: un sistema per l’analisi del sentimento nelle reti sociali. Master’s thesis, Roma Tre University...such as information about the tweet and the user profile. We collected those tweets by means of web crawler and extract several features from the raw...AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS( ES ) Roma Tre University,Department

  19. QU at TREC-2015: Building Real-Time Systems for Tweet Filtering and Question Answering

    Science.gov (United States)

    2015-11-20

    from Yahoo ! An- swers. We adopted a very simple approach that searched an archived Yahoo ! Answers QA dataset for similar questions to the asked ones and...users to post and answer questions. Yahoo ! An- swers1 is by far one of the largest sQA platforms. Questions and answers on such platforms share some...multiple domains [5]. However, the existence of large social question answering websites, such as Yahoo ! Answers specifically, makes the development of

  20. Searching and Filtering Tweets: CSIRO at the TREC 2012 Microblog Track

    Science.gov (United States)

    2012-11-01

    convey emotions such as lol or xoxo could also increase noise in a tweet. We investigated the effect of removing these words from the tweet as well...the common words that convey feelings such as lol , haha, or xoxo, and emoticons such as :-), ☼, or /, and Japanese emoticons such as (>_<). Lexical

  1. CMU OAQA at TREC 2015 LiveQA: Discovering the Right Answer with Clues

    Science.gov (United States)

    2015-11-20

    is no pre-defined answer type; much like the Jeopardy! challenge, we must deal with “ lexical answer types” [1]. CMU’s Open Advancement of Question...when the length of the generated answer passage is greater than 50% of the maximum allowable length (1000 characters). 3 Development Set Analysis The...LiveQA organizers provided a sample of 1000 Yahoo! Answers question IDs (QIDs), which we used as a development set for pre-evaluation analysis

  2. CLIR Experiments at Maryland for TREC-2002: Evidence Combination for Arabic-English Retrieval

    National Research Council Canada - National Science Library

    Darwish, Kareem; Oard, Douglas W

    2003-01-01

    .... Evidence from multiple sources of translation knowledge was combined to estimate translation probabilities, and four techniques for estimating query-language term weights from document-language evidence were tried...

  3. Measuring Robustness with First Relevant Score in the TREC 2012 Microblog Track

    Science.gov (United States)

    2013-02-03

    redirected tweets. We performed our download from June 17-29, 2012, using Myle Ott’s enhanced crawler “AsyncEmbeddedJsonStatusBlockCrawler” of myleott...weekends). We downloaded the urls in random order so any glitches during the download process (e.g., web server rejecting requests for a few minutes...2012), we re-attempted to download the 4,923,108 tweets missing after the first pass, and we did not use the -noFollow option (so that the crawler

  4. SNUMedinfo at TREC CDS Track 2014: Medical Case-based Retrieval Task

    Science.gov (United States)

    2014-11-01

    knowledge-based query expansion We used external medical literature corpus ( MEDLINE ® ) as a tagged knowledge source to acquire useful query expansion terms...We leased the 2014 MEDLINE ® /PubMed® Journal Citations from the U.S. National Library of Medi- cine. There are approximately 22 million MEDLINE ...documents from external corpus ( MEDLINE ) using query likelihood model. We extracted MeSH MajorTopic de- scriptors from top-k ranked documents. The original

  5. San Francisco State University at TREC 2014: Clinical Decision Support Track and Microblog Track

    Science.gov (United States)

    2014-11-01

    One of the parameters used with MetaMap during this run was -y (word sense disambiguation). The option causes MetaMap to attempt to disambiguate...utilized was the -- negex feature that outputs a list of negated UML concepts occurring in the input and the associated strings that caused the negation...syndrome”. At most 2 top entry terms were chosen for any given concept. For example the concept “ syncope ” would be expanded with “drop attack” and

  6. Identifying Patients for Clinical Studies from Electronic Health Records: TREC 2012 Medical Records Track at OHSU

    Science.gov (United States)

    2012-11-01

    for edema, but clearly that was over-restrictive. Another problematic topic was 145 ("Patients with lupus nephritis and thrombotic thrombocytopenic... lupus nephritis and thrombotic thrombocytopenic purpura (((report_text:lupus OR discharge_icd_codes_txt:710.0) AND (report_text:nephritis OR...discharge_icd_codes_txt:580.* OR discharge_icd_codes_txt:582.*)) OR report_text:" lupus nephritis ") AND (report_text:"thrombotic thrombocytopenic purpura

  7. Using Meta-data to Search for Clinical Records: RMIT at TREC 2012 Medical Track

    Science.gov (United States)

    2012-11-01

    coagulant, nos” hip admit treated ”ct angiography” admit ”chest pain” assessed patients ”physical therapy” children received ” cerebral palsy ” admit...rmit.edu.au david.martinez@nicta.edu.au Abstract Clinical records contain International Classification of Dis- eases (ICD) codes summarizing the primary and...Development Activity (ARDA). U.S. Government or Federal Rights License 14. ABSTRACT Clinical records contain International Classification of Diseases

  8. Plantas hipoglicemiantes utilizadas por comunidades tradicionais na Bacia do Alto Paraguai e Vale do Guaporé, Mato Grosso - Brasil

    Directory of Open Access Journals (Sweden)

    M. Macedo

    Full Text Available No Brasil, com inúmeras espécies tropicais, evidencia-se o conhecimento e uso da vegetação medicinal pelas comunidades quilombolas, ribeirinhas, rurais, tradicionais e indígenas, que são praticadas até os dias atuais. O Estado de Mato Grosso pela sua localização no Planalto Central brasileiro possui uma variedade destas comunidades, que utilizam estas plantas medicinais, levando em consideração o conhecimento popular passado de geração em geração. Esta pesquisa visa identificar a forma de coleta e os usos desse grupo vegetal indicados pelos usuários. O estudo foi realizado em 15 comunidades tradicionais (não indígenas na Bacia do Alto Paraguai e 2 (duas no Vale do Guaporé. A coleta de dados deu-se através de líderes comunitários, benzedeiras, parteiras e usuários utilizando o método qualitativo, mediante abordagem qualitativa, com auxílio de entrevistas estruturadas, semi-estruturadas e abertas. Dentre as espécies identificadas 17 estacam-se para o tratamento do Diabetes, dentre elas citam-se: Anacadium humile; Bauhinia glabra; Cecropia pachystachya; Hancornia speciosa; Heteropteris aphrodisiaca; Leonotis nepetifolia; Momordica charantia; Solanum lycocarpum. Registra-se ainda que as partes mais utilizadas desses vegetais são: folhas, casca do caule, raiz, planta toda, brotos, óleos dos frutos e polvilho dos frutos. De acordo com os usuários a maioria das plantas não podem ser colhidas após o nascer do sol e o preparo deve ser feito com folhas secas ou que tenham sido submetidas ao processo de secagem sobre o fogão de lenha ou em local abafado.

  9. Atlantic frugivory: a plant-frugivore interaction data set for the Atlantic Forest.

    Science.gov (United States)

    Bello, Carolina; Galetti, Mauro; Montan, Denise; Pizo, Marco A; Mariguela, Tatiane C; Culot, Laurence; Bufalo, Felipe; Labecca, Fabio; Pedrosa, Felipe; Constantini, Rafaela; Emer, Carine; Silva, Wesley R; da Silva, Fernanda R; Ovaskainen, Otso; Jordano, Pedro

    2017-06-01

    The data set provided here includes 8,320 frugivory interactions (records of pairwise interactions between plant and frugivore species) reported for the Atlantic Forest. The data set includes interactions between 331 vertebrate species (232 birds, 90 mammals, 5 fishes, 1 amphibian, and 3 reptiles) and 788 plant species. We also present information on traits directly related to the frugivory process (endozoochory), such as the size of fruits and seeds and the body mass and gape size of frugivores. Data were extracted from 166 published and unpublished sources spanning from 1961 to 2016. While this is probably the most comprehensive data set available for a tropical ecosystem, it is arguably taxonomically and geographically biased. The plant families better represented are Melastomataceae, Myrtaceae, Moraceae, Urticaceae, and Solanaceae. Myrsine coriacea, Alchornea glandulosa, Cecropia pachystachya, and Trema micrantha are the plant species with the most animal dispersers (83, 76, 76, and 74 species, respectively). Among the animal taxa, the highest number of interactions is reported for birds (3,883) followed by mammals (1,315). The woolly spider monkey or muriqui, Brachyteles arachnoides, and Rufous-bellied Thrush, Turdus rufiventris, are the frugivores with the most diverse fruit diets (137 and 121 plants species, respectively). The most important general patterns that we note are that larger seeded plant species (>12 mm) are mainly eaten by terrestrial mammals (rodents, ungulates, primates, and carnivores) and that birds are the main consumers of fruits with a high concentration of lipids. Our data set is geographically biased, with most interactions recorded for the southeast Atlantic Forest. © 2017 by the Ecological Society of America.

  10. Estrutura da comunidade de morcegos (Mammalia, Chiroptera da Estação Experimental de Itirapina, estado de São Paulo, Brasil

    Directory of Open Access Journals (Sweden)

    Therys M. Sato

    2015-01-01

    Full Text Available A estrutura de comunidades de morcegos no Brasil ainda é pouco estudada e vêm sofrendo sérias modificações devido à perda de habitats. O principal objetivo do presente trabalho foi estudar a comunidade de morcegos da Estação Experimental de Itirapina, município de Itirapina, Estado de São Paulo. Nesta Estação, além das espécies cultivadas de Eucalyptus e Pinus, há diversas plantas que podem fornecer alimento aos morcegos. Entre julho de 2001 e julho de 2006, foram realizadas 58 sessões noturnas de captura de morcegos com 4 a 12 redes-de-neblina dispostas a cada sessão. Nesse período, foram capturados 720 indivíduos de 16 espécies de morcegos dos quais 13 pertencem à família Phyllostomidae, duas à Vespertilionidae e uma à Molossidae. A curva cumulativa de espécies atingiu o equilíbrio, no qual apenas espécies raras são acrescentadas. Cinco espécies (Artibeus lituratus, Platyrrhinus lineatus, Carollia perspicillata, Glossophaga soricina e Sturnira lilium representaram 80% dos morcegos capturados na Estação Experimental, onde se alimentavam de frutos de plantas pioneiras, tais como Cecropia pachystachya, Solanum spp. e Piper spp. A prevalência do vírus rábico foi zero na amostragem das 10 espécies analisadas. Apesar de estar muito modificada, a Estação Experimental de Itirapina pode ser uma importante área de abrigo e alimento para os morcegos e tem potencial de atuar como corredor entre áreas de Cerrado e Mata Atlântica.

  11. Seed banks on Attalea phalerata (Arecaceae) stems in the Pantanal wetland, Brazil

    Science.gov (United States)

    Corrêa, Christiane E.; Fischer, Erich; dos Santos, Flavio A. M.

    2012-01-01

    Background and Aims Seeds can accumulate in the soil or elsewhere, such as on the stems of palms when these are covered by persistent sheaths. These sheaths could act as a safe site for some species. Here, we studied whether persistent sheaths of the palm Attalea phalerata (Arecaceae) are available sites for seed accumulation in the Pantanal wetland of Brazil. We also investigated whether the composition, richness and diversity of species of seeds in the persistent sheaths are determined by habitat (riparian forest and forest patches) and/or season (wet and dry). Methods All accumulated material was collected from ten persistent sheaths along the stems of 64 A. phalerata individuals (16 per habitat and 16 per season). The material was then individually inspected under a stereomicroscope to record seed species and number. Key Results Of the 640 sheaths sampled, 65 % contained seeds (n = 3468). This seed bank included 75 species belonging to 12 families, and was primarily composed of small, endozoochoric seeds, with a few abundant species (Cecropia pachystachya and Ficus pertusa). Moraceae was the richest family (four species) and Urticaceae the most abundant (1594 seeds). Stems of A. phalerata in the riparian forest had 1·8 times more seeds and 1·3 times more species than those in forest patches. In the wet season we sampled 4·1 times more seeds and 2·2 more species on palm stems than in the dry season. Richness did not differ between habitats, but was higher in the wet season. Abundance was higher in forest patches and in the wet season. Conclusions Attalea phalerata stems contain a rich seed bank, comparable to soil seed banks of tropical forests. As most of these seeds are not adapted to grow in flooding conditions, palm stems might be regarded as safe sites for seeds (and seedlings) to escape from the seasonal flooding of the Pantanal. PMID:22210851

  12. Evaluating Stream Filtering for Entity Profile Updates in TREC 2012, 2013, and 2014 (KBA Track Overview, Notebook Paper)

    Science.gov (United States)

    2014-11-01

    Track Overview, Notebook Paper) 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S) 5d. PROJECT NUMBER 5e. TASK NUMBER...using the 2013 data)       2012 2013 2014 Corpus [1] 7 months (4,973 hours) 17 months (11,948 hours) 19 months (13,663 hours) > 400M

  13. TNO and RUN at the TREC 2012 Contextual Suggestion Track : Recommending personalized touristic sights using Google Places

    NARCIS (Netherlands)

    Sappelli, M.; Verberne, S.; Kraaij, W.

    2013-01-01

    The purpose of the Contextual Suggestion track is to suggest personalized touristic activities to an individual, given a certain location and time. In our approach, we collected initial recommendations by using the location context as search query in Google Places. We first ranked the

  14. University of Glasgow at TREC 2014: Experiments with Terrier in Contextual Suggestion, Temporal Summarisation and Web Tracks

    Science.gov (United States)

    2014-11-01

    automatic selec- Report Documentation Page Form ApprovedOMB No. 0704-0188 Public reporting burden for the collection of information is estimated to average 1...this year on the generation of more meaningful and interesting descriptions for each venue sug- gestion , instead of simply returning the LBSN’s... gestions track. Figures in bold represent the top performances. follows. For each venue suggestion, we extracted the reviews that have been entered by

  15. ADAPT.DCU at TREC LiveQA: A Sentence Retrieval based Approach to Live Question Answering

    Science.gov (United States)

    2015-11-20

    list of conceptually similar questions from an index of previously asked on “Yahoo! An- swers”. We then extract the best matching sentences from the...answer reranking. Transactions of the Association for Computational Linguistics , 3:197–210. Higashinaka, R. and Isozaki, H. (2008). Corpus-based question...Proceedings of the 52nd Annual Meeting of the Association for Com- putational Linguistics (Volume 1: Long Papers), pages 977–986, Baltimore, Maryland

  16. Interspecific variation in vitamin E levels and the extent of lipid peroxidation in pioneer and non-pioneer species used in tropical forest restoration.

    Science.gov (United States)

    Contin, Daniele R; Munné-Bosch, Sergi

    2016-09-01

    Reforestation projects have gained interest over recent years due to the loss of biodiversity in tropical regions as a result of large deforestation by anthropogenic actions. However, better knowledge on the tolerance of plant species to environmental stresses is needed for reforestation success. Here, we evaluated the photoprotective and antioxidant capacity, in terms of vitamin E accumulation, of five pioneer (Platypodium elegans Vogel, Schinus terebinthifolius Raddi, Lafoensia pacari A. St.-Hil, Cecropia pachystachya Trécul. and Aegiphila sellowiana Cham.) and five non-pioneer (Myracrodruon urundeuva Allemão, Cedrela fissilis Vell., Genipa americana L., Copaifera langsdorffii Desf. and Hymenaea courbaril L.) species, in relation to the extent of lipid peroxidation in leaves. Furthermore, we examined differences between sun and shade leaves on vitamin E accumulation and the extent of lipid peroxidation. Pioneer plants showed on average 33% higher malondialdehyde levels, an indicator of lipid peroxidation, than non-pioneer species, but no significant differences in vitamin E contents. In contrast, a marked interspecific variation was observed in the levels of α-tocopherol and its precursor, γ-tocopherol. Natural variation revealed interesting relationships between vitamin E levels and the extent of lipid peroxidation in leaves. The pioneer species, P. elegans, did not accumulate α-tocopherol and displayed the highest levels of malondialdehyde. Sun and shade leaves accumulated vitamin E levels to a similar extent, except for the pioneer L. pacari and the non-pioneer C. langsdorffii, the former accumulating more α-tocopherol in sun leaves and the latter in shade leaves. We conclude that interspecific variation is higher than both leaf type and successional-group variation in terms of vitamin E accumulation and the extent of lipid peroxidation, and that vitamin E levels, particularly those of α-tocopherol, negatively correlate with the extent of lipid

  17. Full-texts Representations with Medical Subject Headings, and Co-citations Network Reranking Strategies for TREC 2014 Clinical Decision Support Track

    Science.gov (United States)

    2014-11-01

    evaluation campaigns [7]. MeSH concepts were recog- nised in documents using a classical strict mapping (Rabin- Karp algorithm). See [8] for further...details and evaluation of MeSH recognition by Rabin- Karp algo- rithm. MeSH concepts manually assigned by human in- dexers also could be collected when

  18. Can we Save the rectum by watchful waiting or TransAnal microsurgery following (chemo) Radiotherapy versus Total mesorectal excision for early REctal Cancer (STAR-TREC study)?

    DEFF Research Database (Denmark)

    Rombouts, Anouk J M; Al-Najami, Issam; Abbott, Natalie L

    2017-01-01

    six cases per month internationally during year 2. ETHICS AND DISSEMINATION: The medical ethical committees of all the participating countries have approved the study protocol. Results of the primary and secondary endpoints will be submitted for publication in peer-reviewed journals. TRIAL...

  19. WSU-IR at TREC 2015 Clinical Decision Support Track: Joint Weighting of Explicit and Latent Medical Query Concepts from Diverse Sources

    Science.gov (United States)

    2015-11-20

    ture, is fairly common in clinical practice. Such queries typically correspond to complex information needs, which involve a large number of concepts...or Symptom – Therapeutic or Preventive Procedure This list was obtained from an initial list of 16 semantic types in [9] through backward elimination...semantic concepts from different sources is an effective strategy for CDS retrieval models. References 1. A. R. Aronson. Effective mapping of biomedical

  20. NUDTSNA at TREC 2015 Microblog Track: A Live Retrieval System Framework for Social Network based on Semantic Expansion and Quality Model

    Science.gov (United States)

    2015-11-20

    rank algorithm and dy- namic threshold adjustment which utilize not only semantic features but also social attributes in social media . In periodic...time filtering task, the goal of the real- time filtering task is to explore technologies for monitoring a stream of social media posts with respect to...and recommendation performance in social media . For semantic features, we utilize different retrieval models, such as TFIDF, BM25, key word bool logic

  1. Ethnobotanical study of medicinal plants used by Ribeirinhos in the North Araguaia microregion, Mato Grosso, Brazil.

    Science.gov (United States)

    Ribeiro, Reginaldo Vicente; Bieski, Isanete Geraldini Costa; Balogun, Sikiru Olaitan; Martins, Domingos Tabajara de Oliveira

    2017-06-09

    Currently, in many traditional communities, such as the riverine community in the North Araguaia microregion (Mato Grosso, Brazil), plant knowledge and use represent the main, if not the only, therapeutic resource for the maintenance of health and/or treatment of diseases. This study aimed to identify and document species of medicinal plants used by local experts from riverine communities in the North Araguaia microregion in Mato Grosso State, and to further chemical and pharmacological studies on species selected based on searches in the relevant literature. This is a cross-sectional ethnobotanical study, with non-probabilistic sampling (n =60), that applied the snowball method to select local riverine experts who understand medicinal plant use. Socio-demographic, ethnobotanical and ethnopharmacological data (vernacular name, uses, geographical origin, habit, method of preparation and part used) on medicinal plants were collected during semi-structured interviews. The results were analyzed by descriptive and quantitative means: indices of use-report (UR) were used to select plant species with therapeutic potential. In total, 309 plant species belonging to 86 botanical families were cited; 73% were native to Brazil, and Fabaceae was the most representative family (11.3%). Arboreal was the predominant life form (37.2%). The leaf was the most used part (28.9%). Infusion was the most commonly reported method of preparation (31.3%). The plants reported in the survey were indicated for 18 of the 22 ICD-10 disease categories. The disease categories most commonly cited were the infectious and parasitic diseases (IPD, 718 UR), digestive system diseases (DSD, 565 UR) and respiratory system diseases (RSD, 504 UR), representing 16.6%, 13.1% and 11.7%, respectively of the total UR. Dysphania ambrosioides L. was the most sighted in the IPD category 50 UR. Copaifera langsdorffii Desf. (133), Lafoensia pacari A. St.-Hil. (131), and Cecropia pachystachya Trécul (126) were the

  2. Nutrient fluxes in litterfall of a secondary successional alluvial rain forest in Southern Brazil

    Directory of Open Access Journals (Sweden)

    Maurício Bergamini Scheer

    2011-12-01

    (principalmente de N y P de la vegetación menos desarrollada fue superior a la eficiencia de una más desarrollada, debido a la alta proporción de tres especies nativas dominantes (Myrsine coriacea, Tibouchina pulchra y Cecropia pachystachya en la primera. Si bien la hojarasca de esas especies presenta menor concentración de nutrientes que las otras especies arbóreas, el flujo de nutrientes fue mayor (para ambos sitios, marcando una cierta independencia de los nutrientes esenciales del suelo. Las cantidades de esas especies deberían ser consideradas con mayor atención para su uso en programas de restauración forestal.

  3. Prospective neonatal screening for severe T- and B-lymphocyte deficiencies in Seville.

    Science.gov (United States)

    de Felipe, Beatriz; Olbrich, Peter; Lucenas, José Manuel; Delgado-Pecellin, Carmen; Pavon-Delgado, Antonio; Marquez, Josefina; Salamanca, Carmen; Soler-Palacin, Pere; Gonzalez-Granado, Luis Ignacio; Antolin, Laura Ferreras; Borte, Stephan; Neth, Olaf

    2016-02-01

    Early diagnosis of primary immunodeficiency such as severe combined immunodeficiency (SCID) and X-linked agammaglobulinemia (XLA) improves outcome of affected children. T-cell-receptor-excision circles (TRECs) and kappa-deleting-recombination-excision circles (KRECs) determination from dried blood spots (DBS) identify neonates with severe T- and/or B-lymphopenia. No prospective data exist of the impact of gestational age (GA) and birth weight (BW) on TRECs and KRECs values. TRECs and KRECs determination using triplex RT-PCR (TRECS-KRECS-β-actin-Assay) from prospectively collected DBS between 02/2014 and 02/2015 in three hospitals in Seville, Spain. Cut-off levels were TRECs 700/punch. Internal (SCID, XLA, ataxia telangiectasia) and external controls (NBS quality assurance program, CDC) were included. A total of 5160 DBS were tested. Re-punch was needed in 77 samples (1.5%) due to insufficient β-actin (<700 copies/punch). Pre-term neonates (GA<37 weeks) and neonates with a BW<2500 g showed significantly lower TRECs and KRECs levels (p < 0.001). Due to repeat positive results five neonates were re-called (<0.1%): Fatal chromosomopathy (n = 1; TRECs 1/KRECs 4); extreme pre-maturity (n = 2; TRECs 0/KRECs 0 and TRECs 1/KRECs 20 copies/punch); neonates born to mothers receiving azathioprine during pregnancy (n = 2; TRECs 92/KRECs 1 and TRECs 154/KRECs 3 copies/punch). All internal and external controls were correctly identified. TRECS-KRECS-β-actin-Assay correctly identifies T- and B-cell lymphopenias. Pre-maturity and low BW is associated with lower TREC and KREC levels. Extreme pre-maturity and maternal immune suppressive therapy may be a cause for false positive results of TRECs and KRECs values, respectively. To reduce the rate of insufficient samples, DBS extraction and storage need to be improved. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  4. Consumption of Mullerian Bodies by Golden-olive Woodpecker (Colaptes rubiginosus) in Nicaragua's Highlands

    Science.gov (United States)

    M.A. Torrez; Wayne Arendt; L. Diaz

    2016-01-01

    The Golden-olive Woodpecker is a generalist species found in a wide range of habitats, being particularly common in coffee plantations within Nicaraguan cloud forests. Observations of an individual feeding at the base of Cecropia leaves revealed it was consuming Mullerian bodies that the Cecropia produces to feed Azteca ants as part of a host-inhabitant mutualistic...

  5. Newborn Screening for Primary T- and B-Cell Immune Deficiencies—A Prospective Study in Andalucía

    Directory of Open Access Journals (Sweden)

    Beatriz de Felipe

    2017-10-01

    Full Text Available Background: Quantification of T-cell-receptor-excision circles (TRECs and kappa-deleting-recombination-excision circles (KRECs from dried blood spots (DBS allows detection of neonates with severe T-cell and/or B-cell lymphopenia that are potentially affected by severe combined immunodeficiency (SCID, as well as X-linked agammaglobulinemia (XLA. Methods: Determination of TRECs and KRECs using a triplex RT-PCR (TRECS-KRECS-β-actin assay from prospectively collected DBS between February 2014 and December 2016 in three hospitals in Seville, Spain. Cut-off levels were TRECs < 6/punch, KRECs < 4/punch and b-actin > 700/punch. Internal (SCID, XLA, ataxia telangiectasia and external controls (CDC were included. Results: A total of 8943 DBS samples obtained from 8814 neonates were analysed. Re-punching was necessary in 124 samples (1.4% due to insufficient β-actin values (<700 copies/punch. Preterm neonates (GA < 37 weeks and neonates with a BW < 2500 g showed significantly lower TRECs and KRECs levels (p < 0.001. Due to repeated pathological results, ten neonates were re-sampled (0.11%, of which five neonates (0.055% confirmed the pathological results: one case was a fatal chromosomopathy (TRECs 1/KRECs 4; two were extreme premature newborns (TRECs 0/KRECs 0 and TRECs 1/KRECs 20 copies/punch; and 2 neonates were born to mothers receiving azathioprine during pregnancy (TRECs 92/KRECs 1 and TRECs 154/KRECs 3 copies/punch. All controls were correctly identified. Conclusions: Severe T- and B-cell lymphopenias were correctly identified by the TRECS-KRECS-β-actin assay. Prematurity and low BW are associated with lower TREC and KREC levels. Extreme prematurity and maternal immune suppressive therapy can cause false positive results of TRECs and KRECs values.

  6. Congo, Brazzaville

    African Journals Online (AJOL)

    Achariaceae. Anacardiaceae. Annonaceae. Apocynaceae Bign oniaceae. Burse raceae. Cann abaceae. Cecropia cea e. Chryso balana ceae. Clusia ceae. Combre taceae. Ebenaceae. Euphorbiace ae. Fabaceae. Hypericace ae. Irvingiaceae. Ixonan thacea e. Lauraceae. Lecythidaceae. Loga niaceae. Malvaceae Melia.

  7. Morphological and physio-chemical characterization of five Canistel accessions at the subtropical horticulture research station in Miami Florida

    Science.gov (United States)

    Fruit of five canistel cultivars, 'Fairchild','E11', 'Keisau', 'TREC#3' and 'TREC 3680' were evaluated and characterized at the National Germplasm Repository, Subtropical horticulture Research Station (SHRS) Miami, Florida. Thirty fruits were harvested from clonal accessions during July and August, ...

  8. Evaluation of bovine thymic function by measurement of signal joint T-cell receptor excision circles.

    Science.gov (United States)

    Hisazumi, Rinnosuke; Kayumi, Miya; Zhang, Weidong; Kikukawa, Ryuji; Nasu, Tetuo; Yasuda, Masahiro

    2016-01-01

    A signal joint T-cell receptor excision circle (sjTREC) is a circular DNA produced by T-cell receptor α gene rearrangement in the thymus. Measurements of sjTREC values have been used to evaluate thymic function. We recently established a quantitative PCR (QPCR) assay of bovine sjTREC. In the present study, we used this QPCR assay to measure the sjTREC value in bovine peripheral blood mononuclear cells and we then evaluated the relationships between sjTREC values and peripheral blood T-cell number, growth stage, gender, and meteorological season. The sjTREC value was highest at the neonatal stage, and its value subsequently decreased with age. On the other hand, the peripheral T-cell number increased with age. The sjTREC value in calves up to 50-days old was significantly higher for males than for females, suggesting that thymic function might differ by gender. In addition, the sjTREC value and the peripheral T-cell number were significantly higher in calves in the summer season than in calves in the winter season. These data suggest that bovine thymic function is highly variable and varies according to the growth stage, gender, and environmental factors such as air temperature or the UV index. Copyright © 2015 Elsevier B.V. All rights reserved.

  9. Neonatal screening for severe combined immunodeficiency in Brazil.

    Science.gov (United States)

    Kanegae, Marilia Pyles Patto; Barreiros, Lucila Akune; Mazzucchelli, Juliana Themudo Lessa; Hadachi, Sonia Marchezi; de Figueiredo Ferreira Guilhoto, Laura Maria; Acquesta, Ana Lúcia; Genov, Isabel Rugue; Holanda, Silvia Maia; Di Gesu, Regina Sumiko Watanabe; Goulart, Ana Lucia; Dos Santos, Amélia Miyashiro Nunes; Bellesi, Newton; Costa-Carvalho, Beatriz Tavares; Condino-Neto, Antonio

    2016-01-01

    To apply, in Brazil, the T-cell receptor excision circles (TRECs) quantification technique using real-time polymerase chain reaction in newborn screening for severe combined immunodeficiency and assess the feasibility of implementing it on a large scale in Brazil. 8715 newborn blood samples were collected on filter paper and, after DNA elution, TRECs were quantified by real-time polymerase chain reaction. The cutoff value to determine whether a sample was abnormal was determined by ROC curve analysis, using SSPS. The concentration of TRECs in 8,682 samples ranged from 2 to 2,181TRECs/μL of blood, with mean and median of 324 and 259TRECs/μL, respectively. Forty-nine (0.56%) samples were below the cutoff (30TRECs/μL) and were reanalyzed. Four (0.05%) samples had abnormal results (between 16 and 29TRECs/μL). Samples from patients previously identified as having severe combined immunodeficiency or DiGeorge syndrome were used to validate the assay and all of them showed TRECs below the cutoff. Preterm infants had lower levels of TRECs than full-term neonates. The ROC curve showed a cutoff of 26TRECs/μL, with 100% sensitivity for detecting severe combined immunodeficiency. Using this value, retest and referral rates were 0.43% (37 samples) and 0.03% (3 samples), respectively. The technique is reliable and can be applied on a large scale after the training of technical teams throughout Brazil. Copyright © 2016. Published by Elsevier Editora Ltda.

  10. Core Temperature Measurement During Submaximal Exercise: Esophageal, Rectal, and Intestinal Temperatures

    Science.gov (United States)

    Lee, Stuart M. C.; Williams, W. Jon; Schneider, Suzanne M.

    2000-01-01

    The purpose of this study was to determine if intestinal temperature (Tin) might be in acceptable alternative to esophageal (Tes) and rectal temperature (Trec) to assess thermoregulation during supine exercise. We hypothesized that Tin would have values similar to Tes and a response time similar to Trec, but the rate of temperature change across time would not be different between measurement sites. Seven subjects completed a continuous supine protocol of 20 min of rest, 20 min of cycle exercise at 40% peak oxygen consumption (VO2pk), 20 min of cycle exercise at 65% V02pk, and 20 min of recovery. Tes, Trec, and Tin were recorded each min throughout the test. Temperatures were not different after 20 min of rest, but Trec was less than the Tes and Tin at the end of the 40% and 65% VO2pk stages. After 20 min of recovery, Tes was less than either Trec or Tin, which were not different from each other. Time to threshold for increased temperature from rest was greater for Trec than Tes but not different from Tin. Time to reach peak temperature was greater for Tin and Trec than Tes. Similarly, time to a decrease in temperature after exercise was greater for Trec than Tes, but not different from Tin. The rate of temperature change from threshold to the end of the 40% VO2pk stage was not different between measurement sites. However, the rate of change during recovery was more negative for Tes than Tin and Trec, which were different from each other. Measurement of Tin may he an acceptable alternative to Tes and Trec with an understanding of its limitations.

  11. A temporary social parasite of tropical plant-ants improves the fitness of a myrmecophyte

    Science.gov (United States)

    Dejean, Alain; Leroy, Céline; Corbara, Bruno; Céréghino, Régis; Roux, Olivier; Hérault, Bruno; Rossi, Vivien; Guerrero, Roberto J.; Delabie, Jacques H. C.; Orivel, Jérôme; Boulay, Raphaël

    2010-10-01

    Myrmecophytes offer plant-ants a nesting place in exchange for protection from their enemies, particularly defoliators. These obligate ant-plant mutualisms are common model systems for studying factors that allow horizontally transmitted mutualisms to persist since parasites of ant-myrmecophyte mutualisms exploit the rewards provided by host plants whilst providing no protection in return. In pioneer formations in French Guiana, Azteca alfari and Azteca ovaticeps are known to be mutualists of myrmecophytic Cecropia ( Cecropia ants). Here, we show that Azteca andreae, whose colonies build carton nests on myrmecophytic Cecropia, is not a parasite of Azteca- Cecropia mutualisms nor is it a temporary social parasite of A. alfari; it is, however, a temporary social parasite of A. ovaticeps. Contrarily to the two mutualistic Azteca species that are only occasional predators feeding mostly on hemipteran honeydew and food bodies provided by the host trees, A. andreae workers, which also attend hemipterans, do not exploit the food bodies. Rather, they employ an effective hunting technique where the leaf margins are fringed with ambushing workers, waiting for insects to alight. As a result, the host trees’ fitness is not affected as A. andreae colonies protect their foliage better than do mutualistic Azteca species resulting in greater fruit production. Yet, contrarily to mutualistic Azteca, when host tree development does not keep pace with colony growth, A. andreae workers forage on surrounding plants; the colonies can even move to a non- Cecropia tree.

  12. Gains from an integrated market for tradable renewable energy credits

    International Nuclear Information System (INIS)

    Mozumder, Pallab; Marathe, Achla

    2004-01-01

    Decoupling the environmental attributes of renewable energy (RE) generation from the physical unit of energy is an innovative mechanism for marketing green or renewable power. The introduction of 'Tradable Renewable Energy Credits' (TRECs) allows the green power attributes of energy to be sold or traded separately from the physical unit of energy. Since the green power certificate system removes potential locational and physical bottlenecks, both suppliers and consumers gain flexibility in the marketplace. The TREC is also an efficient tool to meet 'Renewable Portfolio Standard' (RPS) required by different states in the US. This paper discusses the RPS requirements for different states and examines the implications of an integrated TREC market. It offers a competitive setting to the consumers to pay for renewable energy and a cost effective tool to support renewable energy generation [Grace and Wiser, 2002]. This paper also highlights some practical difficulties that should be addressed in order to establish an efficient integrated TREC market

  13. A Call to Include Severe Combined Immunodeficiency in Newborn Screening Program

    OpenAIRE

    Raz Somech; Amos Etzioni

    2014-01-01

    Quantification of the T cell receptor excision circles (TRECs) has recently emerged as a useful non-invasive clinical and research tool to investigate thymic activity. It allows the identification of T cell production by the thymus. Quantification of TREC copies has recently been implemented as the preferred test to screen neonates with severe combined immunodeficiency (SCID) or significant lymphopenia. Neonatal genetic screening for SCID is highly important in countries with high rates of co...

  14. Using Stream Features for Instant Document Filtering

    Science.gov (United States)

    2012-11-01

    retrieved by the Crawler 13The TREC proceedings will be probably available in the first quarter 2013 http://trec.nist.gov/proceedings/ proceedings.html...maximize the performance of the system. References [1] Andreas Bauer and Christian Wolff. Event based classi- fication of Web 2.0 text streams...twitter links. In WSDM ’11: Proceedings of the fourth ACM international conference on Web search and data mining. ACM Request Permis- sions, February

  15. Isolation of genes involved in biofilm formation of a Klebsiella pneumoniae strain causing pyogenic liver abscess.

    Directory of Open Access Journals (Sweden)

    Meng-Chuan Wu

    Full Text Available BACKGROUND: Community-acquired pyogenic liver abscess (PLA complicated with meningitis and endophthalmitis caused by Klebsiella pneumoniae is an emerging infectious disease. To investigate the mechanisms and effects of biofilm formation of K. pneumoniae causing PLA, microtiter plate assays were used to determine the levels of biofilm formed by K. pneumoniae clinical isolates and to screen for biofilm-altered mutants from a transposon mutant library of a K. pneumoniae PLA-associated strain. METHODOLOGY/PRINCIPAL FINDINGS: The biofilm formation of K. pneumoniae was examined by microtiter plate assay. Higher levels of biofilm formation were demonstrated by K. pneumoniae strains associated with PLA. A total of 23 biofilm-decreased mutants and 4 biofilm-increased mutants were identified. Among these mutants, a biofilm-decreased treC mutant displayed less mucoviscosity and produced less capsular polysaccharide (CPS, whereas a biofilm-increased sugE mutant displayed higher mucoviscosity and produced more CPS. The biofilm phenotypes of treC and sugE mutants also were confirmed by glass slide culture. Deletion of treC, which encodes trehalose-6-phosphate hydrolase, impaired bacterial trehalose utilization. Addition of glucose to the culture medium restored the capsule production and biofilm formation in the treC mutant. Transcriptional profile analysis suggested that the increase of CPS production in ΔsugE may reflect elevated cps gene expression (upregulated through rmpA in combination with increased treC expression. In vivo competition assays demonstrated that the treC mutant strain was attenuated in competitiveness during intragastric infection in mice. CONCLUSIONS/SIGNIFICANCE: Genes important for biofilm formation by K. pneumoniae PLA strain were identified using an in vitro assay. Among the identified genes, treC and sugE affect biofilm formation by modulating CPS production. The importance of treC in gastrointestinal tract colonization suggests

  16. Crecimiento y mortalidad en juveniles de siete especies arbóreas en un bosque muy húmedo tropical intervenido de Costa Rica

    Directory of Open Access Journals (Sweden)

    Grace Sáenz

    1999-06-01

    Full Text Available Se estudiaron por un período de cuatro años los patrones de crecimiento en diámetro y altura, así como la mortalidad de brinzales (individuos e 0.30 m altura y Diameter and height growth patterns, as well as the incidence of seedling (individuals e0.3 m and <1.5 m in height and sapling (individual e1.5 m in height and 9.9 cm DBH mortality were studied for four years in a forest under two types of silvicultural intervention. The study is based on anual measurements of individuals from the two size categories marked one year after harvest. In the case of the seedlings, the parameters evaluated were: total height and diameter at 10 cm from the base. For the sapling category, the diameter at 1.30 m was also measured. The Clark and Clark methodology was used to evaluate the crown illumination index of all individuals. Seven tree species were studied: Cecropia (two species, Cecropia insignis Liebm. and Cecropia obtusifolia Bertol., Laetia procera (Poepp. Eichler, Rollinia pittieri Saff, Apeiba membranacea Spruce ex Benth., Virola koschnyi Warb. y Virola sebifera Aubl. The Cecropia spp. seedlings showed the highest diameter and height growth rates, with annual mean increments in diameter of 7.8 mm/years and height of 188 cm/years. The L. procera saplings had the greatest diameter and height growth, with rates of 7.0 mm/year and 86 cm/year, respectively. Only in the case of Cecropia spp. and V. sebifera are diameter and height growth significantly correlated with the crown light index. Seedlings had the highest mortality rates in all species except Cecropia spp. and R. pittieri, where the sapling mortality was greater.

  17. A New Species of Neotropical Carpenter Ant in the Genus Camponotus (Hymenoptera: Formicidae, Apparently without Major Workers

    Directory of Open Access Journals (Sweden)

    William Mackay

    2012-01-01

    Full Text Available We describe a new species of carpenter ants from Ecuador, which apparently has an obligatory relationship with the ant plants Cecropia membranacea Trécul, C. herthae Diels and C. marginalis Cuatrec. The workers are relatively small and hairy, and based on a number of collections, it does not appear to have major workers. We compare the new species to Camponotus balzani, to which it appears to be similar and which has normal major workers, and also lives in Cecropia spp.

  18. Late Holocene history of savannah gallery forest from Carimagua area, Colombia

    International Nuclear Information System (INIS)

    Berrio, Juan Carlos; Hooghiemstra, Henry; Behling, Hermann; Van Der Borg

    2002-01-01

    The pollen record of a 65-cm long core Laguna Carimagua-Bosque (4 degrade 04' N, 70 degrade 13' W) shows the late Holocene environmental history from a lake located within the gallery forest of the savannahs of the llanos Orientales of Colombia. Nine AMS radiocarbon dates of the organic deposits show the core represents the period from c. 1300 14 C yr BP to the present. The lake evolved from an active drainage system. During the period from c. 1300 to 875 14 C yr BP (zone CMB-Ia) Mauritia dominated swamp and gallery forest was present dominated by Cecropia, and later also Acalypha and Alchornea. From 875 to 700 14 C yr BP (zone CMB Ib) the lake was completely surrounded by gallery forest. Mauritiella and Cecropia occurred around the lake. Cecropia pioneer forest reached its greatest abundance and became gradually replaced by a more species rich gallery forest, including Acalypha, Alchornea, Euterpe/Geonoma, Moraceae/Urticaceae, Piperaceae, and Virola. From 700 to 125 14 C yr BP (zone CMB - II) Cecropia lost its dominant role and Mauritiella palms became more frequent. Main vegetation categories were swamp forest, gallery forest, under story elements, savannah shrubs and trees, and grass savannah. From 125 14 C yr BP to recent (zone CMB -III) plant diversity in the gallery forest became highest, Mauritiella became very abundant and among the savannah elements woody Didymopanax increased

  19. The relative importance of above- versus belowground competition for tree growth during early succession of a tropical moist forest

    DEFF Research Database (Denmark)

    Breugel, Michiel van; van Breugel, Paulo; Jansen, Patrick A.

    2012-01-01

    fertility in Southern Mexico, using the premise that competition for light is size-asymmetric, unlike competition for nutrients. Plant growth is thus expected to be disproportionally impeded by larger neighbors. We studied how growth and survival of 3.5-5.5 m tall saplings of Cecropia peltata...

  20. Mycobiota associated with the ambrosia beetle Scolytodes unipunctatus (Coleoptera: Curculionidae, Scolytinae)

    Czech Academy of Sciences Publication Activity Database

    Kolařík, Miroslav; Hulcr, J.

    2009-01-01

    Roč. 113, č. 1 (2009), s. 44-60 ISSN 0953-7562 Grant - others:PřF UK(CZ) GP206/08/P322 Program:GP Institutional research plan: CEZ:AV0Z50200510 Keywords : ambrosia fungi * custingophora * custingophora cecropiae Subject RIV: EE - Microbiology, Virology Impact factor: 2.921, year: 2009

  1. Association of CD4+ T-lymphocyte counts and new thymic emigrants in HIV-infected children during successful highly active antiretroviral therapy.

    Science.gov (United States)

    Saitoh, Akihiko; Singh, Kumud K; Sandall, Sharsti; Powell, Christine A; Fenton, Terrence; Fletcher, Courtney V; Hsia, Karen; Spector, Stephen A

    2006-04-01

    In a cohort of children receiving highly active antiretroviral therapy (HAART) with sustained plasma HIV-1 RNA counts compared with children who reached undetectable plasma HIV-1 RNA by week 8 (rapid responders) throughout HAART. To determine whether levels of T-cell receptor excision circles (TRECs) could explain the apparent inconsistency between the quantity of HIV-1 DNA and CD4+ T-lymphocyte counts in HIV-1-infected children receiving HAART with sustained virologic suppression. T-cell receptor excision circles and HIV-1 DNA and plasma HIV-1 RNA were quantified longitudinally by PCR in 31 children (median age, 5.6 years) with sustained undetectable plasma HIV-1 RNA for >104 weeks of HAART. There was a positive correlation between TREC and HIV-1 DNA during HAART, notably at weeks 48 and 80 (P counts (P < .001) and percentages (P = .05). Median TREC levels were consistently equal or higher in slow responders compared with rapid responders (P < .001) despite slow responders having consistently greater quantities of HIV-1 DNA. To maintain adequate levels of CD4+ T-lymphocytes, children with high HIV-1 DNA maintain high levels of TREC while receiving HAART. Thus, a thymic control mechanism is required to maintain new CD4+ T lymphocytes in the presence of persistent virus. The TREC level is a useful marker of thymic function in HIV-infected children.

  2. How one teacher research experience program is transforming STEM education

    Science.gov (United States)

    Warburton, J.; Fahnestock, J.; Larson, A.

    2016-12-01

    Celebrating over 10 years of success, the PolarTREC-Teachers and Researchers Exploring and Collaborating program, administered by the Arctic Research Consortium of the United States, is a unique professional development program for United States educators and polar researchers. Through an innovative teacher research experience, utilizing field-based experiences in the polar regions, PolarTREC provides teachers the content knowledge, pedagogical tools, confidence, understanding of science in the broader society, and experiences with scientific inquiry they need to promote authentic scientific research in their classroom. The program evaluation objectives were 1) to better understand the immediate impacts of the program on participating teachers, their students, and the researchers with whom they partnered; and 2) to explore the long-term impacts of the PolarTREC experiences on participating teachers' professional experiences, and in particular their use of authentic scientific research with their students and ongoing relationships with researcher team members and other PolarTREC teachers. In this presentation, we will share our data on how the PolarTREC model is transforming STEM educators not only how they teach science in their classroom but also how they both perceive science, a paradigm shift, that defines their careers.

  3. Inverse associations between obesity indicators and thymic T-cell production levels in aging atomic-bomb survivors.

    Directory of Open Access Journals (Sweden)

    Kengo Yoshida

    Full Text Available Reduction of the naive T-cell population represents a deteriorating state in the immune system that occurs with advancing age. In animal model studies, obesity compromises the T-cell immune system as a result of enhanced adipogenesis in primary lymphoid organs and systemic inflammation. In this study, to test the hypothesis that obesity may contribute to the aging of human T-cell immunity, a thousand atomic-bomb survivors were examined for obesity status and ability to produce naive T cells, i.e., T-cell receptor excision circle (TREC numbers in CD4 and CD8 T cells. The number of TRECs showed a strong positive correlation with naive T cell numbers, and lower TREC numbers were associated with higher age. We found that the TREC number was inversely associated with levels of obesity indicators (BMI, hemoglobin A1c and serum CRP levels. Development of type-2 diabetes and fatty liver was also associated with lower TREC numbers. This population study suggests that obesity with enhanced inflammation is involved in aging of the human T-cell immune system. Given the fact that obesity increases the risk of numerous age-related diseases, attenuated immune competence is a possible mechanistic link between obesity and disease development among the elderly.

  4. Inverse associations between obesity indicators and thymic T-cell production levels in aging atomic-bomb survivors.

    Science.gov (United States)

    Yoshida, Kengo; Nakashima, Eiji; Kubo, Yoshiko; Yamaoka, Mika; Kajimura, Junko; Kyoizumi, Seishi; Hayashi, Tomonori; Ohishi, Waka; Kusunoki, Yoichiro

    2014-01-01

    Reduction of the naive T-cell population represents a deteriorating state in the immune system that occurs with advancing age. In animal model studies, obesity compromises the T-cell immune system as a result of enhanced adipogenesis in primary lymphoid organs and systemic inflammation. In this study, to test the hypothesis that obesity may contribute to the aging of human T-cell immunity, a thousand atomic-bomb survivors were examined for obesity status and ability to produce naive T cells, i.e., T-cell receptor excision circle (TREC) numbers in CD4 and CD8 T cells. The number of TRECs showed a strong positive correlation with naive T cell numbers, and lower TREC numbers were associated with higher age. We found that the TREC number was inversely associated with levels of obesity indicators (BMI, hemoglobin A1c) and serum CRP levels. Development of type-2 diabetes and fatty liver was also associated with lower TREC numbers. This population study suggests that obesity with enhanced inflammation is involved in aging of the human T-cell immune system. Given the fact that obesity increases the risk of numerous age-related diseases, attenuated immune competence is a possible mechanistic link between obesity and disease development among the elderly.

  5. Quantitative near-infrared spectroscopy on patients with peripheral vascular disease

    Science.gov (United States)

    Franceschini, Maria-Angela; Fantini, Sergio; Palumbo, Renato; Pasqualini, Leonella; Vaudo, Gaetano; Franceschini, Edoardo; Gratton, Enrico; Palumbo, Barbara; Innocente, Salvatore; Mannarino, Elmo

    1998-01-01

    We have used near-infrared spectroscopy to measure the hemoglobin saturation at rest and during exercise on patients affected by peripheral vascular disease (PVD). The instrument used in our study is a frequency-domain tissue oximeter which employs intensity modulated (110 MHz) laser diodes. We examined 9 subjects, 3 of which were controls and 6 were patients affected by stage II PVD. The optical probe was located on the calf muscle of the subjects. The measurement protocol consisted of: (1) baseline (approximately 5 min); (2) stationary bicycle exercise (approximately 5 min); (3) recovery (approximately 15 min). The change in hemoglobin saturation during exercise ((Delta) Y) and the recovery time after exercise (trec) were significantly greater in the PVD patients ((Delta) Y equals -21 +/- 3%, trec equals 5.9 +/- 3.8 min) than in the control subjects ((Delta) Y equals 2 +/- 3%, trec equals 0.6 +/- 0.1 min).

  6. A Call to Include Severe Combined Immunodeficiency in Newborn Screening Program

    Directory of Open Access Journals (Sweden)

    Raz Somech

    2014-01-01

    Full Text Available Quantification of the T cell receptor excision circles (TRECs has recently emerged as a useful non-invasive clinical and research tool to investigate thymic activity. It allows the identification of T cell production by the thymus. Quantification of TREC copies has recently been implemented as the preferred test to screen neonates with severe combined immunodeficiency (SCID or significant lymphopenia. Neonatal genetic screening for SCID is highly important in countries with high rates of consanguinous marriages, such as Israel, and can be used for early diagnosis, enabling prompt therapeutic intervention that will save lives and improve the outcome of these patients. TREC measurement is also applicable in clinical settings where T cell immunity is involved, including any T cell immunodeficiencies, HIV infection, the aging process, autoimmune diseases, and immune reconstitution after bone marrow transplantation.

  7. Probing and mapping the binding sites on streptavidin imprinted polymer surface

    International Nuclear Information System (INIS)

    Duman, Memed

    2014-01-01

    Molecular imprinting is an effective technique for preparing recognition sites which act as synthetic receptors on polymeric surfaces. Herein, we synthesized MIP surfaces with specific binding sites for streptavidin and characterized them at nanoscale by using two different atomic force microscopy (AFM) techniques. While the single molecule force spectroscopy (SMFS) reveals the unbinding kinetics between streptavidin molecule and binding sites, simultaneous topography and recognition imaging (TREC) was employed, for the first time, to directly map the binding sites on streptavidin imprinted polymers. Streptavidin modified AFM cantilever showed specific unbinding events with an unbinding force around 300 pN and the binding probability was calculated as 35.2% at a given loading rate. In order to prove the specificity of the interaction, free streptavidin molecules were added to AFM liquid cell and the binding probability was significantly decreased to 7.6%. Moreover, the recognition maps show that the smallest recognition site with a diameter of around ∼ 21 nm which corresponds to a single streptavidin molecule binding site. We believe that the potential of combining SMFS and TREC opens new possibilities for the characterization of MIP surfaces with single molecule resolution under physiological conditions. - Graphical abstract: Simultaneous Topography and RECognition (TREC) imaging is a novel characterization technique to reveal binding sites on molecularly imprinted polymer surfaces with single molecule resolution under physiological conditions. - Highlights: • Highly specific streptavidin printed polymer surfaces were synthesized. • Unbinding kinetic rate of single streptavidin molecule was studied by SMFS. • The distribution of binding pockets was revealed for the first time by TREC imaging. • TREC showed that the binding pockets formed nano-domains on MIP surface. • SMFS and TREC are powerful AFM techniques for characterization of MIP surfaces

  8. Objective and automated protocols for the evaluation of biomedical search engines using No Title Evaluation protocols.

    Science.gov (United States)

    Campagne, Fabien

    2008-02-29

    The evaluation of information retrieval techniques has traditionally relied on human judges to determine which documents are relevant to a query and which are not. This protocol is used in the Text Retrieval Evaluation Conference (TREC), organized annually for the past 15 years, to support the unbiased evaluation of novel information retrieval approaches. The TREC Genomics Track has recently been introduced to measure the performance of information retrieval for biomedical applications. We describe two protocols for evaluating biomedical information retrieval techniques without human relevance judgments. We call these protocols No Title Evaluation (NT Evaluation). The first protocol measures performance for focused searches, where only one relevant document exists for each query. The second protocol measures performance for queries expected to have potentially many relevant documents per query (high-recall searches). Both protocols take advantage of the clear separation of titles and abstracts found in Medline. We compare the performance obtained with these evaluation protocols to results obtained by reusing the relevance judgments produced in the 2004 and 2005 TREC Genomics Track and observe significant correlations between performance rankings generated by our approach and TREC. Spearman's correlation coefficients in the range of 0.79-0.92 are observed comparing bpref measured with NT Evaluation or with TREC evaluations. For comparison, coefficients in the range 0.86-0.94 can be observed when evaluating the same set of methods with data from two independent TREC Genomics Track evaluations. We discuss the advantages of NT Evaluation over the TRels and the data fusion evaluation protocols introduced recently. Our results suggest that the NT Evaluation protocols described here could be used to optimize some search engine parameters before human evaluation. Further research is needed to determine if NT Evaluation or variants of these protocols can fully substitute

  9. Enhanced algorithms for enterprise expert search system

    Science.gov (United States)

    Molokanov, Valentin; Romanov, Dmitry; Tsibulsky, Valentin

    2013-03-01

    We present the results of our enterprise expert search system application to the task introduced at the Text Retrieval Conference (TREC) in 2007. The expert search system is based on analysis of content and communications topology in an enterprise information space. An optimal set of weighting coefficients for three query-candidate associating algorithms is selected for achieving the best search efficiency on the search collection. The obtained performance proved to be better than at most TREC participants. The hypothesis of additional efficiency improvement by means of query classification is proposed.

  10. Detection of newly produced T and B lymphocytes by digital PCR in blood stored dry on nylon flocked swabs.

    Science.gov (United States)

    Tessitore, Marion Vaglio; Sottini, Alessandra; Roccaro, Aldo M; Ghidini, Claudia; Bernardi, Simona; Martellosio, Giovanni; Serana, Federico; Imberti, Luisa

    2017-04-05

    A normal number of T-cell receptor excision circles (TRECs) and K-deleting recombination excision circles (KRECs) is considered a biomarker for adequate new T- and B-cell production. In newborns, detection of TRECs and KRECs by real time PCR from dried blood spotted on filter paper is used for the screening of severe immunodeficiency. In adults, elderly and during diseases, where the number of TRECs is lower than in newborns and children, a large amount of DNA and a sensitive method of amplification are necessary to identify newly produced lymphocytes. DNA was prepared from blood of 203 healthy adults (range: 18-91 years old) absorbed for 10 s on flocked swabs and let to dry, or from peripheral blood mononuclear cells. DNA was subjected to digital PCR and to well established conventional real time PCR-based method using TREC- and KREC-specific primers and probes. The number of TRECs and KRECs was expressed per mL of blood. Statistical analysis was performed by nested ANOVA, Pearson coefficient of determination, and by linear regression tests. The novel method for the storage of dried blood on nylon flocked swabs and the use of digital PCR allow quantification of TRECs and KRECs with high degree of sensitivity, specificity, accuracy, and precision. TRECs and KRECs were amplified by digital PCR in all tested blood samples, including those obtained from elderly individuals (>70 years old) and that were negative by real time PCR. Furthermore, values of TRECs and KRECs obtained by digital PCR were in the range of those acquired by real time PCR. Our findings demonstrate that DNA isolation from dried blood on flocked swabs followed by digital PCR-based analysis represents a useful tool for studying new lymphocyte production in adults and elderly individuals. This suggests the potential use of the methodology when monitoring of clinical variables is limited by the number of molecules that can be amplified and detected, such as in patients with immunodeficiency or under

  11. Anti-stress and Adaptogenic Activity of l-Arginine Supplementation

    Directory of Open Access Journals (Sweden)

    Vanita Gupta

    2005-01-01

    Full Text Available In the present study, oral supplementation of l-arginine in rats was evaluated for its anti-stress and adaptogenic activity using the cold (5°C–hypoxia (428 mmHg–restraint (C-H-R animal model. A dose-dependent study of l-arginine was carried out at doses of 12.5, 25.0, 50.0, 100.0, 200.0 and 500.0 mg/kg body weight, administered orally 30 min prior to C-H-R exposure. The time taken by the rat to attain a rectal temperature of 23°C (Trec 23°C during C-H-R exposure and its recovery to Trec 37°C at normal atmospheric pressure and 32 ± 1°C were used as biomarkers of anti-stress and adaptogenic activity. Biochemical parameters related to lipid peroxidation, anti-oxidants, cell membrane permeability, nitric oxide and stress, with and without administration of the least effective l-arginine dose, were measured in rats on attaining Trec 23°C and Trec 37°C. The least effective adaptogenic dose of l-arginine was 100.0 mg/kg body weight. The C-H-R exposure of control rats, on attaining Trec 23°C, resulted in a significant increase in plasma malondialdehyde (MDA, blood lactate dehydrogenase (LDH and a decrease in blood catalase (CAT and plasma testosterone levels. On recovery (Trec 37°C of control rats, there was a further decrease in CAT and plasma testosterone, and an increase in LDH. l-Arginine supplementation resulted in a significant decrease in plasma MDA, an increase in blood superoxide dismutase (SOD, CAT levels maintained at control values and a lower increase in LDH compared with controls (45.3 versus 58.5% and 21.5 versus 105.2% on attaining Trec 23°C during C-H-R exposure and on recovery to Trec 37°C. The results suggested that l-arginine possesses potent anti-stress activity during C-H-R exposure and recovery from C-H-R-induced hypothermia.

  12. New species and records of Scolytodes (Coleoptera, Curculionidae: Scolytinae) from South America.

    Science.gov (United States)

    Jordal, Bjarte H

    2013-01-01

    Seventeen new species of Scolytodes Ferrari are described from Venezuela, Ecuador, Peru, Bolivia and Argentina: Scolytodes cenchros, S. concavifrons, S. conpunctus, S. fraterniatratus, S. frontocarinatus, S. solarius and S. trigonus from Cecropia leafstalks; S. pascopomus from a fruit husk; S. obovatus, S. clusiaphilus, S. clusiapraelatus and S. uniseriatus from Clusia litter sifting; S. grossepunctatus and S. fulvus from general litter sifting; and S. inusitatus, S. sagittarius and S. sus collected by flight intercept traps. The synonymy of S. imitans and S. nitidissimus is confirmed. Additional South American records are given for S. chapuisi (Ecuador), S. interpunctatus (Peru), S. maurus (Ecuador), and S. suspectus (Ecuador), all taken from Cecropia leafstalks, and S. similis (Peru) and S. unipunctatus (Bolivia).

  13. A new record of fungus-beetle symbiosis in Scolytodes bark beetles (Scolytinae, Curculionidae, Coleoptera)

    Czech Academy of Sciences Publication Activity Database

    Hulcr, J.; Kolařík, Miroslav; Kirkendall, L.

    2007-01-01

    Roč. 43, - (2007), s. 151-159 ISSN 0334-5114 Grant - others:GA ČR(CZ) GD206/03/H034 Program:GD Institutional research plan: CEZ:AV0Z50200510 Source of funding: V - iné verejné zdroje Keywords : scolytodes unipunctatus * cecropia * raffaela Subject RIV: EE - Microbiology, Virology Impact factor: 0.598, year: 2007

  14. A Picture Guide to Trees of the Gamboa Area, Republic of Panama.

    Science.gov (United States)

    1985-10-01

    flowergmidl cream petals with (12cm in yellow center diameter) Figure 6. Gustavia superba. Cecropia species Guarumo Moraceae Leaves Leaves are large (60 cm... Moraceae Leaves The leaves (25 by 15 cm) are simple, alternate, very thick and leathery, with an uneven leaf base. The leaves grow in clumps; they have...Ficus insipida Wild Fig Moraceae Leaves The leaves are simple (15 by 7 cm), alternate, and tough. The

  15. Late Holocene history of savanna gallery forest from Carimagua area, Colombia.

    Science.gov (United States)

    Berrio; Hooghiemstra; Behling; van der Borg K

    2000-09-01

    The pollen record of a 65cm long core Laguna Carimagua-Bosque (4 degrees 04'N, 70 degrees 13'W) shows the late Holocene environmental history from a lake located within the gallery forest of the savannas of the Llanos Orientales of Colombia. Nine AMS radiocarbon dates of the organic deposits show that the core represents the period from ca. 1300(14)CyrBP to the present. The lake evolved from an active drainage system.During the period from ca. 1300 to 875(14)CyrBP (zone CMB-Ia), Mauritia-dominated swamp and gallery forest was present, dominated by Cecropia, and later also Acalypha and Alchornea. From 875 to 700(14)CyrBP (zone CMB-Ib), the lake was completely surrounded by gallery forest. Mauritiella and Cecropia occurred around the lake. Cecropia pioneer forest reached its greatest abundance and became gradually replaced by a more species-rich gallery forest, including Acalypha, Alchornea, Euterpe/Geonoma, Moraceae/Urticaceae, Piperaceae, and Virola. From 700 to 125(14)CyrBP (zone CMB-II), Cecropia lost its dominant role, and Mauritiella palms became more frequent. The main vegetation categories were swamp forest, gallery forest, understory elements, savanna shrubs and trees, and grass savanna. From 125(14)CyrBP to recent (zone CMB-III), the plant diversity in the gallery forest became highest, Mauritiella became very abundant, and among the savanna elements, woody Didymopanax increased.Comparison of four pollen records from savanna sites shows that pollen of savanna vegetation is markedly underrepresented in lake sediments when the lake lies within the gallery forest. As most of the drainage system of a savanna is hidden by gallery forest, we also expect a significant underrepresentation of the savanna ecosystem in river-transported pollen assemblages.

  16. Effet de la teneur en protéines alimentaires sur la croissance de l ...

    African Journals Online (AJOL)

    Ce travail vise à étudier l'effet du régime et de la teneur en protéine brute alimentaire sur la croissance de l'escargot Archachatina marginata (Swainson, 1821) en captivité. Le régime R1 est constitué de Lactuca sativa (Asteraceae), de Carica papaya (Caricaceae), Brassica oleracea (Brassicaceae), de Cecropia peltata ...

  17. The importance of anchor text for ad hoc search revisited

    NARCIS (Netherlands)

    Koolen, M.; Kamps, J.; Chen, H.-H.; Efthimiadis, E.N.; Savoy, J.; Crestani, F.; Marchand-Maillet, S.

    2010-01-01

    It is generally believed that propagated anchor text is very important for effective Web search as offered by the commercial search engines. "Google Bombs" are a notable illustration of this. However, many years of TREC Web retrieval research failed to establish the effectiveness of link evidence

  18. Late Data Fusion for Microblog Search

    NARCIS (Netherlands)

    Liang, S.; de Rijke, M.; Tsagkias, M.

    2013-01-01

    The character of microblog environments raises challenges for microblog search because relevancy becomes one of the many aspects for ranking documents. We concentrate on merging multiple ranking strategies at post-retrieval time for the TREC Microblog task. We compare several state-of-the-art late

  19. Thymic function recovery after unrelated donor cord blood or T-cell depleted HLA-haploidentical stem cell transplantation correlates with leukemia relapse

    Science.gov (United States)

    Clave, Emmanuel; Lisini, Daniela; Douay, Corinne; Giorgiani, Giovanna; Busson, Marc; Zecca, Marco; Moretta, Francesca; Acquafredda, Gloria; Brescia, Letizia P.; Locatelli, Franco; Toubert, Antoine

    2013-01-01

    Use of alternative donors/sources of hematopoietic stem cells (HSC), such as cord blood (CB) or HLA-haploidentical (Haplo)-related donors, is associated with a significant delay in immune reconstitution after transplantation. Long-term T-cell immune reconstitution largely relies on the generation of new T cells in the recipient thymus, which can be evaluated through signal joint (sj) and beta T-cell-Receptor Excision Circles (TREC) quantification. We studied two groups of 33 and 24 children receiving, respectively, HSC Transplantation (HSCT) from an HLA-haploidentical family donor or an unrelated CB donor, for both malignant (46) and non-malignant disorders (11). Relative and absolute sj and beta-TREC values indicated comparable thymic function reconstitution at 3 and 6 months after the allograft in both groups. Compared to children with non-malignant disorders, those with hematological malignancies had significantly lower pre-transplantation TREC counts. Patients who relapsed after HSCT had a significantly less efficient thymic function both before and 6 months after HSCT with especially low beta-TREC values, this finding suggesting an impact of early intra-thymic T-cell differentiation on the occurrence of leukemia relapse. PMID:23459761

  20. An effective statistical approach to blog post opinion retrieval

    NARCIS (Netherlands)

    He, B.; Macdonald, C.; He, J.; Ounis, I.; Shanahan, J.G.; Amer-Yahia, S.; Zhang, Y.; Kołcz, A.; Chowdury, A.; Kelly, D.

    2008-01-01

    Finding opinionated blog posts is still an open problem in information retrieval, as exemplified by the recent TREC blog tracks. Most of the current solutions involve the use of external resources and manual efforts in identifying subjective features. In this paper, we propose a novel and effective

  1. Author Details

    African Journals Online (AJOL)

    Dunn, A. Vol 16, No 2 (2013) - Articles T-REC: Strengthening capacity for blood transfusion research in Ghana and Zimbabwe Abstract. ISSN: 1560-8646. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of ...

  2. Exploration of a Geometric Model of Data Fusion.

    Science.gov (United States)

    Ibraev, Ulukbek; Ng, Kwong Bor; Kantor, Paul B.

    2002-01-01

    Explores aspects of data fusion (DF) for information retrieval (IR) using a set of data from the Fifth International Conference on Text Retrieval (TREC5). Derives an equation for effective DF based on a geometric model and shows that the performance of a pair of IR schemes may be approximated by a quadratic polynomial. (Author/LRW)

  3. Severe combined immunodeficiency: From its discovery to the perspective.

    Science.gov (United States)

    Kanegane, Hirokazu; Imai, Kohsuke; Morio, Tomohiro

    2017-01-01

    Severe combined immunodeficiency (SCID) is impaired in lymphocyte development and function. Affected children have extreme susceptibility to infections, which are fatal in the first year of life without treatment. The estimate of incidence is one in approximately 50,000 live birth. The first series of diseases were described in 1950s, and all patients died in infancy. The first transplant for SCID was carried out in 1968, and it has been described that SCID patients could be treated by hematopoietic stem cell transplantation (HSCT) since then. Adenosine deaminase and common gamma chain were identified to be causative genes for SCID in 1972 and 1993, respectively. SCID arises from a variety of genetic defects. The early intervention of healthy SCID infants without infections affords higher survival rate, and newborn screening (NBS) was suggested. T-cell receptor (TCR) exicision circles (TRECs) are circular DNA formed from the leftover fragment generated from the TCR rearrangement. TRECs can be measured from a small aliquot of DNA such as Guthrie card by quantitative PCR. SCID patients lack TRECs, and TRECs quantification is useful for NBS for SCID. NBS for SCID have been already carried out in most of the Unite States, and the early introduction is desired in Japan to save SCID children.

  4. Valuing soil conservation benefits of agroforestry: contour hedgerows in the Eastern Visayas, Philippines

    Science.gov (United States)

    Subhrendu Patanayak; D. Evan Mercer

    1998-01-01

    Trecs can he considered as investments made by economic agents to prevent depreciation of natural assets such as stocks of top soil and water. In agroforestq systems farmers use trees in this manner by deliberately combining them with agricultural crops on the same unit of land. Although advocates of agroforestry have asserted that soil conservation is one of its...

  5. Concept based document retrieval for genomics literature

    NARCIS (Netherlands)

    Trieschnigg, D.; Kraaij, W.; Schuemie, M.

    2006-01-01

    The 2006 TREC Genomics evaluation focuses on document, passage and aspect retrieval in the genomics domain. The Erasmus Medical Center, TNO and University of Twente collaborated on an approach combining concept tagging (named entity recognition) and information retrieval based on statistical

  6. Concept based document retrieval for genomics literature

    NARCIS (Netherlands)

    Trieschnigg, Rudolf Berend; Kraaij, Wessel; Schuemie, Martijn; Voorhees, E.M; Buckland, L.P.

    2006-01-01

    The 2006 TREC Genomics evaluation focuses on document, passage and aspect retrieval in the genomics domain. The Erasmus Medical Center, TNO and University of Twente collaborated on an approach combining concept tagging (named entity recognition) and information retrieval based on language models.

  7. Aspects of Sentence Retrieval

    Science.gov (United States)

    2006-09-01

    1999. [4] Allan, James, Carbonell, Jaime , Doddington, George, Yamron, Jonathan, and Yang, Yiming. Topic detection and tracking pilot study final report... Sabine . Using grammatical relations, answer frequencies and the world wide web for TREC question answering. In Proceedings of the Tenth Text Retrieval

  8. FedWeb Greatest Hits: Presenting the New Test Collection for Federated Web Search

    NARCIS (Netherlands)

    Demeester, Thomas; Trieschnigg, Rudolf Berend; Zhou, Ke; Nguyen, Dong-Phuong; Hiemstra, Djoerd

    This paper presents 'FedWeb Greatest Hits', a large new test collection for research in web information retrieval. As a combination and extension of the datasets used in the TREC Federated Web Search Track, this collection opens up new research possibilities on federated web search challenges, as

  9. Recommending personalized touristic sights using Google Places

    NARCIS (Netherlands)

    Sappelli, M.; Kraaij, W.; Verberne, S.

    2013-01-01

    The purpose of the Contextual Suggestion track, an evaluation task at the TREC 2012 conference, is to suggest personalized tourist activities to an individual, given a certain location and time. In our content-based approach, we collected initial recommendations using the location context as search

  10. Learning to rank from relevance feedback for e-discovery

    NARCIS (Netherlands)

    Lubell-Doughtie, P.; Hofmann, K.

    2012-01-01

    In recall-oriented search tasks retrieval systems are privy to a greater amount of user feedback. In this paper we present a novel method of combining relevance feedback with learning to rank. Our experiments use data from the 2010 TREC Legal track to demonstrate that learning to rank can tune

  11. Relevance feedback in probabilistic multimedia retrieval

    NARCIS (Netherlands)

    Boldareva, L.; Hiemstra, Djoerd; Jonker, Willem

    In this paper we explore a new view on data organisation and retrieval in a (multimedia) collection. We use probabilistic framework for indexing and interactive retrieval of the data, which enable to fill the semantic gap. Semi-automated experiments with TREC-2002 video collection showed that our

  12. Africa Sanguine - Vol 16, No 2 (2013)

    African Journals Online (AJOL)

    T-REC: Strengthening capacity for blood transfusion research in Ghana and Zimbabwe · EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. A Dunn, D Ansong, D Mvere, J Ansah, S Owusu-Ofori, E Gomo, I Bates, 14-18 ...

  13. Query and document models for enterprise search

    NARCIS (Netherlands)

    Balog, K.; Hofmann, K.; Weerkamp, W.; de Rijke, M.; Voorhees, E.M.; Buckland, L.P.

    2008-01-01

    We describe our participation in the TREC 2007 Enterprise track and detail our language modeling-based approaches. For document search, our focus was on estimating a mixture model using a standard web collection, and on constructing query models by employing blind relevance feedback and using the

  14. heat storage in upper and lower body during high-intensity exercise ...

    African Journals Online (AJOL)

    work at 80% of peak heart rate (HR) in room temperature . However, upper-body skin .... exercise (ACE) test to determine VO2 peak with gas exchange in- .... Lower-body heat storage was calculated using ∆Trec and ∆Tsk, which was calculated using the mean skin temperature (thigh 70% and calf 30%) from the formula of ...

  15. Incidence of severe combined immunodeficiency through newborn screening in a Chinese population

    Directory of Open Access Journals (Sweden)

    Yin-Hsiu Chien

    2015-01-01

    Conclusion: Newborn screening to measure the number of TREC copies successfully identifies newborns with T-cell lymphopenia, 22q11.2 microdeletion syndrome, and other high-risk conditions. Taken together, the incidence of T-cell lymphopenia in apparently healthy newborns is more than 1 in 11,821, and further attention to their immune functions is warranted.

  16. Evaluating Mobile Proactive Context-Aware Retrieval

    DEFF Research Database (Denmark)

    Menegon, Davide; Mizzaro, Stefano; Nazzi, Elena

    We present the evaluation of a novel application for Web content perusal by means of context-aware mobile devices that proactively query an external search engine. To this aim, we develop a TREC-like benchmark and we use it to evaluate different strategies for automatic query construction...

  17. Biological screening of selected medicinal Panamanian plants by radioligand-binding techniques.

    Science.gov (United States)

    Caballero-George, C; Vanderheyden, P M; Solis, P N; Pieters, L; Shahat, A A; Gupta, M P; Vauquelin, G; Vlietinck, A J

    2001-01-01

    Nineteen plants from the Republic of Panama were selected by their traditional uses in the treatment of hypertension, cardiovascular, mental and feeding disorders and 149 extracts were screened using radioligand-receptor-binding assays. The methanol:dicloromethane extracts of the bark and leaves of Anacardium occidentale L., the leaves of Begonia urophylla Hook., the roots of Bocconia frutescens L., the stems and leaves of Cecropia cf.obtusifolia Bertol., the branches of Clusia coclensis Standl., the bark of Cochlospermum vitifolium (Willd.)Spreng., the roots of Dimerocostus strobilaceus Kuntze, the bark of Guazuma ulmifolia Lam., the leaves of Persea americana Mill. and the branches of Witheringia solanaceae L'Her. inhibited the [3H]-AT II binding (angiotensin II AT1 receptor) more than 50%. Only extracts of the roots of Dimerocostus strobilaceus Kuntze and the stems of Psychotria elata (Sw.) Hammel were potent inhibitors of the [3H] NPY binding (neuropeptide Y Y1 receptor) more than 50% and the ethanolic extracts of the leaves of Cecropia cf. obtusifolia Bertol., the leaves of Hedyosmum bonplandianum H.B.K., the roots of Bocconia frutescens L., the stem of Cecropia cf. obtusifolia Bertol. and the branches of Psychotria elata (Sw.) Hammel showed high inhibition of the [3H] BQ-123 binding (endothelin-1 ET(A) receptor) in a preliminary screening. These results promote the further investigation of these plants using the same assays.

  18. First Year of Israeli Newborn Screening for Severe Combined Immunodeficiency—Clinical Achievements and Insights

    Directory of Open Access Journals (Sweden)

    Erez Rechavi

    2017-11-01

    Full Text Available Severe combined immunodeficiency (SCID, the most severe form of T cell immunodeficiency, is detectable through quantification of T cell receptor excision circles (TRECs in dried blood spots obtained at birth. Herein, we describe the results of the first year of the Israeli SCID newborn screening (NBS program. This important, life-saving screening test is available at no cost for every newborn in Israel. Eight SCID patients were diagnosed through the NBS program in its first year, revealing an incidence of 1:22,500 births in the Israeli population. Consanguine marriages and Muslim ethnic origin were found to be a risk factor in affected newborns, and a founder effect was detected for both IL7Rα and DCLRE1C deficiency SCID. Lymphocyte subset analysis and TREC quantification in the peripheral blood appear to be sufficient for confirmation of typical and leaky SCID and ruling out false positive (FP results. Detection of secondary targets (infants with non-SCID lymphopenia did not significantly affect the management or outcomes of these infants in our cohort. In the general, non-immunodeficient population, TREC rises along with gestational age and birth weight, and is significantly higher in females and the firstborn of twin pairs. Low TREC correlates with both gestational age and birth weight in extremely premature newborns. Additionally, the rate of TREC increase per week consistently accelerates with gestational age. Together, these findings mandate a lower cutoff or a more lenient screening algorithm for extremely premature infants, in order to reduce the high rate of FPs within this group. A significant surge in TREC values was observed between 28 and 30 weeks of gestation, where median TREC copy numbers rise by 50% over 2 weeks. These findings suggest a maturational step in T cell development around week 29 gestation, and imply moderate to late preterms should be screened with the same cutoff as term infants. The SCID NBS program is still

  19. Insights into the impact and use of research results in a residential long-term care facility: a case study

    Directory of Open Access Journals (Sweden)

    Cranley Lisa A

    2012-09-01

    Full Text Available Abstract Background Engaging end-users of research in the process of disseminating findings may increase the relevance of findings and their impact for users. We report findings from a case study that explored how involvement with the Translating Research in Elder Care (TREC study influenced management and staff at one of 36 TREC facilities. We conducted the study at ‘Restwood’ (pseudonym nursing home because the Director of Care engaged actively in the study and TREC data showed that this site differed on some areas from other nursing homes in the province. The aims of the case study were two-fold: to gain a better understanding of how frontline staff engage with the research process, and to gain a better understanding of how to share more detailed research results with management. Methods We developed an Expanded Feedback Report for use during this study. In it, we presented survey results that compared Restwood to the best performing site on all variables and participating sites in the province. Data were collected regarding the Expanded Feedback Report through interviews with management. Data from staff were collected through interviews and observation. We used content analysis to derive themes to describe key aspects related to the study aims. Results We observed the importance of understanding organizational routines and the impact of key events in the facility’s environment. We gleaned additional information that validated findings from prior feedback mechanisms within TREC. Another predominant theme was the sense that the opportunity to engage in a research process was reaffirming for staff (particularly healthcare aides—what they did and said mattered, and TREC provided a means of having one’s voice heard. We gained valuable insight from the Director of Care about how to structure and format more detailed findings to assist with interpretation and use of results. Conclusions Four themes emerged regarding staff engagement with

  20. Insights into the impact and use of research results in a residential long-term care facility: a case study

    Science.gov (United States)

    2012-01-01

    Background Engaging end-users of research in the process of disseminating findings may increase the relevance of findings and their impact for users. We report findings from a case study that explored how involvement with the Translating Research in Elder Care (TREC) study influenced management and staff at one of 36 TREC facilities. We conducted the study at ‘Restwood’ (pseudonym) nursing home because the Director of Care engaged actively in the study and TREC data showed that this site differed on some areas from other nursing homes in the province. The aims of the case study were two-fold: to gain a better understanding of how frontline staff engage with the research process, and to gain a better understanding of how to share more detailed research results with management. Methods We developed an Expanded Feedback Report for use during this study. In it, we presented survey results that compared Restwood to the best performing site on all variables and participating sites in the province. Data were collected regarding the Expanded Feedback Report through interviews with management. Data from staff were collected through interviews and observation. We used content analysis to derive themes to describe key aspects related to the study aims. Results We observed the importance of understanding organizational routines and the impact of key events in the facility’s environment. We gleaned additional information that validated findings from prior feedback mechanisms within TREC. Another predominant theme was the sense that the opportunity to engage in a research process was reaffirming for staff (particularly healthcare aides)—what they did and said mattered, and TREC provided a means of having one’s voice heard. We gained valuable insight from the Director of Care about how to structure and format more detailed findings to assist with interpretation and use of results. Conclusions Four themes emerged regarding staff engagement with the research process

  1. A comparison of cooling methods used in therapeutic hypothermia for perinatal asphyxia.

    Science.gov (United States)

    Hoque, Nicholas; Chakkarapani, Ela; Liu, Xun; Thoresen, Marianne

    2010-07-01

    The objective of this study was to compare cooling methods during therapeutic hypothermia (TH) for moderate or severe perinatal asphyxia with regard to temperature and hemodynamic stability. A total of 73 newborns received TH in our center between 1999 and 2009 by 4 methods: (1) selective head cooling with mild systemic hypothermia by using cap (SHC; n = 20); (2) whole-body cooling with mattress manually controlled (WBCmc; n = 23); (3) whole-body cooling with body wrap servo-controlled (WBCsc; n = 28); and (4) whole-body cooling with water-filled gloves (n = 2). Target rectal temperatures (Trec) were 34.5 +/- 0.5 degrees C (SHC) and 33.5 +/- 0.5 degrees C (WBC). Trec, mean arterial blood pressure, and heart rate were collected from retrospective chart review. Groups had similar baseline characteristics and condition at birth. Trec was within target temperature +/-0.5 degree C for 97% of the time in infants with WBCsc, 81% in infants with WBCmc, 76% in infants with SHC, and 74% in infants who were cooled with gloves. Mean overshoot was 0.3 degree C for WBCsc, 1.3 degrees C for WBCmc, and 0.8 degree C for SHC groups. There was no difference in mean arterial blood pressure or mean heart between groups during the maintenance of cooling. In infants who were rewarmed at similar speed, there was greater variation in Trec in the SHC compared with the WBCsc group. Manually controlled cooling systems are associated with greater variability in Trec compared with servo-controlled systems. A manual mattress often causes initial overcooling. It is unknown whether large variation in temperature adversely affects the neuroprotection of TH.

  2. Cold-Water Immersion for Hyperthermic Humans Wearing American Football Uniforms.

    Science.gov (United States)

    Miller, Kevin C; Swartz, Erik E; Long, Blaine C

    2015-08-01

    Current treatment recommendations for American football players with exertional heatstroke are to remove clothing and equipment and immerse the body in cold water. It is unknown if wearing a full American football uniform during cold-water immersion (CWI) impairs rectal temperature (Trec) cooling or exacerbates hypothermic afterdrop. To determine the time to cool Trec from 39.5°C to 38.0°C while participants wore a full American football uniform or control uniform during CWI and to determine the uniform's effect on Trec recovery postimmersion. Crossover study. Laboratory. A total of 18 hydrated, physically active, unacclimated men (age = 22 ± 3 years, height = 178.8 ± 6.8 cm, mass = 82.3 ± 12.6 kg, body fat = 13% ± 4%, body surface area = 2.0 ± 0.2 m(2)). Participants wore the control uniform (undergarments, shorts, crew socks, tennis shoes) or full uniform (control plus T-shirt; tennis shoes; jersey; game pants; padding over knees, thighs, and tailbone; helmet; and shoulder pads). They exercised (temperature approximately 40°C, relative humidity approximately 35%) until Trec reached 39.5°C. They removed their T-shirts and shoes and were then immersed in water (approximately 10°C) while wearing each uniform configuration; time to cool Trec to 38.0°C (in minutes) was recorded. We measured Trec (°C) every 5 minutes for 30 minutes after immersion. Time to cool from 39.5°C to 38.0°C and Trec. The Trec cooled to 38.0°C in 6.19 ± 2.02 minutes in full uniform and 8.49 ± 4.78 minutes in control uniform (t17 = -2.1, P = .03; effect size = 0.48) corresponding to cooling rates of 0.28°C·min(-1) ± 0.12°C·min(-1) in full uniform and 0.23°C·min(-1) ± 0.11°C·min(-1) in control uniform (t17 = 1.6, P = .07, effect size = 0.44). The Trec postimmersion recovery did not differ between conditions over time (F1,17 = 0.6, P = .59). We speculate that higher skin temperatures before CWI, less shivering, and greater conductive cooling explained the faster cooling

  3. Should we feed back research results in the midst of a study?

    Directory of Open Access Journals (Sweden)

    Estabrooks Carole A

    2012-09-01

    Full Text Available Abstract Background This report is an introduction to a series of three research papers that describe the evolution of the approaches taken by the Translating Research in Elder Care (TREC research team during its first four years to feed back the research findings to study participants. TREC is an observational multi-method health services research project underway in 36 nursing homes in the prairie provinces of Canada. TREC has actively involved decision makers from the sector in all stages from initial planning, through data collection to dissemination activities. However, it was not planned as a fully integrated knowledge translation project. These three papers describe our progress towards fully integrated knowledge translation—with respect to timely and requested feedback processes. The first paper reports on the process and outcomes of creating and evaluating the feedback of research findings to healthcare aides (unregulated health professionals. These aides provide over 80% of the direct care in our sample and actively requested the feedback as a condition of their continued cooperation in the data acquisition process. The second paper describes feedback from nursing home administrators on preliminary research findings (a facility annual report and evaluation of the reports’ utility. The third paper discusses an approach to providing a more in-depth form of feedback (expanded feedback report at one of the TREC nursing homes. Findings Survey and interview feedback from healthcare aides is presented in the first paper. Overall, healthcare aides’ opinions about presentation of the feedback report and the understand ability, usability, and usefulness of the content were positive. The second paper describes the use of telephone interviews with facility administrators and indicates that the majority of contextual areas (e.g., staff job satisfaction addressed in facility annual report to be useful, meaningful, and understandable. More than

  4. Simultaneous AFM topography and recognition imaging at the plasma membrane of mammalian cells.

    Science.gov (United States)

    Chtcheglova, Lilia A; Hinterdorfer, Peter

    2018-01-01

    Elucidation the nano-organization of membrane proteins at/within the plasma membrane is probably the most demanding and still challenging task in cell biology since requires experimental approaches with nanoscale resolution. During last decade, atomic force microscopy (AFM)-based simultaneous topography and recognition imaging (TREC) has become a powerful tool to quickly obtain local receptor nano-maps on complex heterogeneous biosurfaces such as cells and membranes. Here we emphasize the TREC technique and explain how to unravel the nano-landscape of mammalian cells. We describe the procedures for all steps of the experiment including tip functionalization with ligand molecules, sample preparation, and localization of key molecules on the cell surface. We also discuss the current limitations and future perspectives of this technique. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  5. T-cell receptor excisional circles, telomere length, proliferation and apoptosis in peripheral blood mononuclear cells of human immunodeficiency virus-infected individuals after 18 months of treatment induced viral suppression

    DEFF Research Database (Denmark)

    Aladdin, H; Katzenstein, T; Dreves, A.-M.

    2003-01-01

    immunodeficiency virus (HIV)-infected individuals followed for 18 months during HAART. Our results show that HAART significantly increased the level of TRECs in CD4+ cells (P = 0.003) after 18 months of almost continuously suppressed HIV-RNA levels. Lymphocyte proliferative responses and apoptosis levels...... in patients were significantly lower and significantly higher, respectively, compared with healthy controls. The proliferative response and apoptosis levels did not change during follow up. Changes in telomere length were observed in CD4+ and in CD8+ T cells. The study demonstrated that HAART induces normal...... TREC levels in the CD4+ T-cell pool. However, the other perturbed functions in T cells indicate that immune reconstitution is incomplete and may need longer viral suppression....

  6. Plantas de ocorrência espontânea como substratos alternativos para fitoseídeos (Acari, Phytoseiidae em cultivos de seringueira Hevea brasiliensis Muell. Arg. (Euphorbiaceae Weeds as alternative substrates to phytoseiids (Acari, Phytoseiidae in rubber tree Hevea brasilienis, Muell. Arg. (Euphorbiaceae cultivation

    Directory of Open Access Journals (Sweden)

    Marcos Roberto Bellini

    2005-03-01

    Full Text Available O objetivo deste estudo foi determinar as espécies de plantas espontâneas em áreas de cultivo de seringueira que poderiam servir com reservatório de ácaros predadores. O trabalho foi conduzido em Olímpia, Estado de São Paulo, Brasil, em dois cultivos de seringueira. A cada três meses, cerca de 1.000 cm³ de folhas de cada uma das cinco espécies de plantas espontâneas dominantes em cada cultivo foi tomada para determinar os fitoseídeos. Como as plantas espontâneas dominantes variaram durante o estudo, um total de 20 espécies foi verificado. Somente Cecropia sp. foi dominante em todo estudo, em ambos os cultivos. Um total de 336 fitoseídeos pertencentes às seguintes espécies foi encontrado: Euseius citrifolius Denmark & Muma, 1970, E. concordis (Chant, 1959, Galendromus annectens (DeLeon, 1958, Iphiseiodes zuluagai Denmark & Muma, 1972, Neoseiulus anonymus (Chant & Baker, 1965 e N. tunus (DeLeon, 1967. E. citrifolius (189 espécimes e N. tunus (138 espécimes foram os mais abundantes. A maior abundância (231espécimes e diversidade (5 espécies foram observadas sobre Cecropia sp. Sobre esta planta foi encontrado o maior número de ácaros por amostra (29 espécimes, seguida por Piper duncum Linnaeus (22, Guarea sp. (18 e Ageratum conyzoides Linnaeus (12. E. citrifolius tem sido determinado como um dos ácaros predadores mais abundantes sobre seringueiras cultivadas na região onde este trabalho foi conduzido. Cecropia sp. parece ser uma das plantas espontâneas mais importantes consideradas como reservatório de E. citrifolius porque está continuamente presente nos cultivos. Estudos complementares poderiam indicar a viabilidade de se manejar esta planta nas áreas de cultivo de seringueira para permitir o controle biológico dos ácaros-praga desta cultura.The objective of this study was to determine weed species of rubber tree cultivation areas that could serve as reservoirs of predatory mites. The work was conducted in Ol

  7. Pioneering the Transdisciplinary Team Science Approach: Lessons Learned from National Cancer Institute Grantees

    Science.gov (United States)

    Vogel, Amanda L; Stipelman, Brooke A; Hall, Kara L; Nebeling, Linda; Stokols, Daniel; Spruijt-Metz, Donna

    2014-01-01

    The National Cancer Institute has been a leader in supporting transdisciplinary (TD) team science. From 2005-2010, the NCI supported Transdisciplinary Research on Energetic and Cancer I (TREC I), a center initiative fostering the TD integration of social, behavioral, and biological sciences to examine the relationships among obesity, nutrition, physical activity and cancer. In the final year of TREC I, we conducted qualitative in-depth-interviews with 31 participating investigators and trainees to learn more about their experiences with TD team science, including challenges, facilitating factors, strategies for success, and impacts. Five main challenges emerged: (1) limited published guidance for how to engage in TD team science, when TREC I was implemented; (2) conceptual and scientific challenges inherent to efforts to achieve TD integration; (3) discipline-based differences in values, terminology, methods, and work styles; (4) project management challenges involved in TD team science; and (5) traditional incentive and reward systems that do not recognize or reward TD team science. Four main facilitating factors and strategies for success emerged: (1) beneficial attitudes and beliefs about TD research and team science; (2) effective team processes; (3) brokering and bridge-building activities by individuals holding particular roles in a research center; and (4) funding initiative characteristics that support TD team science. Broad impacts of participating in TD team science in the context of TREC I included: (1) new positive attitudes about TD research and team science; (2) new boundary-crossing collaborations; (3) scientific advances related to research approaches, findings, and dissemination; (4) institutional culture change and resource creation in support of TD team science; and (5) career advancement. Funding agencies, academic institutions, and scholarly journals can help to foster TD team science through funding opportunities, institutional policies on

  8. A multiplex immunoassay using the Guthrie specimen to detect T-cell deficiencies including severe combined immunodeficiency disease.

    Science.gov (United States)

    Janik, David K; Lindau-Shepard, Barbara; Comeau, Anne Marie; Pass, Kenneth A

    2010-09-01

    Severe combined immunodeficiency (SCID) fulfills many of the requirements for addition to a newborn screening panel. Two newborn screening SCID pilot studies are now underway using the T-cell receptor excision circle (TREC) assay, a molecular technique. Here we describe an immunoassay with CD3 as a marker for T cells and CD45 as a marker for total leukocytes that can be used with the Guthrie specimen. The multiplexing capabilities of the Luminex platform were used. Antibody pairs were used to capture and detect CD3 and CD45 from a single 3-mm punch of the Guthrie specimen. The assay for each biomarker was developed separately in identical buffers and then combined to create a multiplex assay. Using calibrators made from known amounts of leukocytes, a detection limit of 0.25 x 10(6) cells/mL for CD3 and 0.125 x 10(6) cells/mL for CD45 was obtained. Affinity tests showed no cross-reactivity between the antibodies to CD3 and CD45. The multiplex assay was validated against 8 coded specimens of known clinical status and linked to results from the TREC assay that had identified them. All were correctly identified by the CD345 assay. The performance parameters of the CD345 assay met the performance characteristics generally accepted for immunoassays. Our assay classifications of positive specimens concur with previous TREC results. This CD345 assay warrants evaluation as a viable alternative or complement to the TREC assay as a primary screening tool for detecting T-cell immunodeficiencies, including SCID, in Guthrie specimens.

  9. Diagnosis of immunodeficiency caused by a purine nucleoside phosphorylase defect by using tandem mass spectrometry on dried blood spots.

    Science.gov (United States)

    la Marca, Giancarlo; Canessa, Clementina; Giocaliere, Elisa; Romano, Francesca; Malvagia, Sabrina; Funghini, Silvia; Moriondo, Maria; Valleriani, Claudia; Lippi, Francesca; Ombrone, Daniela; Della Bona, Maria Luisa; Speckmann, Carsten; Borte, Stephan; Brodszki, Nicholas; Gennery, Andrew R; Weinacht, Katja; Celmeli, Fatih; Pagel, Julia; de Martino, Maurizio; Guerrini, Renzo; Wittkowski, Helmut; Santisteban, Ines; Bali, Pawan; Ikinciogullari, Aydan; Hershfield, Michael; Notarangelo, Luigi D; Resti, Massimo; Azzari, Chiara

    2014-07-01

    Purine nucleoside phosphorylase (PNP) deficiency is a rare form of autosomal recessive combined primary immunodeficiency caused by a enzyme defect leading to the accumulation of inosine, 2'-deoxy-inosine (dIno), guanosine, and 2'-deoxy-guanosine (dGuo) in all cells, especially lymphocytes. Treatments are available and curative for PNP deficiency, but their efficacy depends on the early approach. PNP-combined immunodeficiency complies with the criteria for inclusion in a newborn screening program. This study evaluate whether mass spectrometry can identify metabolite abnormalities in dried blood spots (DBSs) from affected patients, with the final goal of individuating the disease at birth during routine newborn screening. DBS samples from 9 patients with genetically confirmed PNP-combined immunodeficiency, 10,000 DBS samples from healthy newborns, and 240 DBSs from healthy donors of different age ranges were examined. Inosine, dIno, guanosine, and dGuo were tested by using tandem mass spectrometry (TMS). T-cell receptor excision circle (TREC) and kappa-deleting recombination excision circle (KREC) levels were evaluated by using quantitative RT-PCR only for the 2 patients (patients 8 and 9) whose neonatal DBSs were available. Mean levels of guanosine, inosine, dGuo, and dIno were 4.4, 133.3, 3.6, and 3.8 μmol/L, respectively, in affected patients. No indeterminate or false-positive results were found. In patient 8 TREC levels were borderline and KREC levels were abnormal; in patient 9 TRECs were undetectable, whereas KREC levels were normal. TMS is a valid method for diagnosis of PNP deficiency on DBSs of affected patients at a negligible cost. TMS identifies newborns with PNP deficiency, whereas TREC or KREC measurement alone can fail. Copyright © 2014 American Academy of Allergy, Asthma & Immunology. Published by Mosby, Inc. All rights reserved.

  10. Instance-Based Question Answering

    Science.gov (United States)

    2006-12-01

    included factoid questions grouped around a set of target entities. For example, for the target entity “ Franz Kafka ”, associated questions included: “Where...from Franz Schubert. A year later he did on Dec 5th.”). Depending on the task, an answer extractor may identify very small, factoid candidates which...IWP): Paraphrase Ac- quisition and Applications, 2003. [55] A. Ittycheriah, M. Franz , and S. Roukos. Ibm’s statistical question answering system - trec

  11. Advanced portrayal of SMIL coating by allying CZE performance with in-capillary topographic and charge-related surface characterization

    Energy Technology Data Exchange (ETDEWEB)

    Stock, Lorenz G. [Division of Chemistry and Bioanalytics, University Salzburg, Hellbrunnerstrasse 34, 5020 Salzburg (Austria); Christian Doppler Laboratory for Innovative Tools for the Characterization of Biosimilars, Hellbrunnerstrasse 34, 5020 Salzburg (Austria); Leitner, Michael; Traxler, Lukas [Institute of Biophysics, Johannes Kepler University Linz, Gruberstrasse 40, 4020 Linz (Austria); Bonazza, Klaus [Institute of Chemical Technologies and Analytics, Vienna University of Technology, Getreidemarkt 9/164, 1060 Vienna (Austria); Leclercq, Laurent; Cottet, Hervé [Institut des Biomolécules Max Mousseron (IBMM), UMR 5247, CNRS, Université de Montpellier, Ecole Nationale Supérieure de Chimie de Montpellier, Place Eugène Bataillon, CC 1706, 34095 Montpellier (France); Friedbacher, Gernot [Institute of Chemical Technologies and Analytics, Vienna University of Technology, Getreidemarkt 9/164, 1060 Vienna (Austria); Ebner, Andreas [Institute of Biophysics, Johannes Kepler University Linz, Gruberstrasse 40, 4020 Linz (Austria); Stutz, Hanno, E-mail: hanno.stutz@sbg.ac.at [Division of Chemistry and Bioanalytics, University Salzburg, Hellbrunnerstrasse 34, 5020 Salzburg (Austria); Christian Doppler Laboratory for Innovative Tools for the Characterization of Biosimilars, Hellbrunnerstrasse 34, 5020 Salzburg (Austria)

    2017-01-25

    A successive multiple ionic polymer layer (SMIL) coating composed of four layers improved the capillary electrophoretic separation of a recombinant major birch pollen allergen and closely related variants when poly(acrylamide-co-2-acrylamido-2-methyl-1-propansulfonate) (55% PAMAMPS) replaced dextran sulfate as terminal SMIL layer. 55% PAMAMPS decelerated the electroosmotic flow (EOF) due to its lower charge density. Atomic force microscopy (AFM) was used to investigate SMIL properties directly on the inner capillary surface and to relate them to EOF measurements and results of associated CZE separations of a mixture of model proteins and peptides that were performed in the same capillary. For the first time, AFM-based biosensing topography and recognition imaging mode (TREC) under liquid conditions was applied for a sequential characterization of the inner surface of a SMIL coated capillary after selected treatments including pristine SMIL, SMIL after contact with the model mixture, after alkaline rinsing, and the replenishment of the terminal polyelectrolyte layer. A cantilever with tip-tethered avidin was used to determine the charge homogeneity of the SMIL surface in the TREC mode. SMIL coated rectangular capillaries with 100 μm internal diameter assured accessibility of the inner surface for this cantilever type. Observed changes in CZE performance and EOF mobility during capillary treatment were also reflected by alterations in surface roughness and charge distribution of the SMIL coating. A renewal of the terminal SMIL layer restored the original surface properties of SMIL and the separation performance. The alliance of the novel TREC approach and CZE results allows for an improved understanding and a comprehensive insight in effects occurring on capillary coatings. - Highlights: • SMIL coating with a terminal layer of reduced charge density improves CZE separation. • Capillaries with rectangular diameter allow for in-capillary TREC-AFM measurement.

  12. Pioneering the Transdisciplinary Team Science Approach: Lessons Learned from National Cancer Institute Grantees.

    Science.gov (United States)

    Vogel, Amanda L; Stipelman, Brooke A; Hall, Kara L; Nebeling, Linda; Stokols, Daniel; Spruijt-Metz, Donna

    2014-01-01

    The National Cancer Institute has been a leader in supporting transdisciplinary (TD) team science. From 2005-2010, the NCI supported Transdisciplinary Research on Energetic and Cancer I (TREC I), a center initiative fostering the TD integration of social, behavioral, and biological sciences to examine the relationships among obesity, nutrition, physical activity and cancer. In the final year of TREC I, we conducted qualitative in-depth-interviews with 31 participating investigators and trainees to learn more about their experiences with TD team science, including challenges, facilitating factors, strategies for success, and impacts. Five main challenges emerged: (1) limited published guidance for how to engage in TD team science, when TREC I was implemented; (2) conceptual and scientific challenges inherent to efforts to achieve TD integration; (3) discipline-based differences in values, terminology, methods, and work styles; (4) project management challenges involved in TD team science; and (5) traditional incentive and reward systems that do not recognize or reward TD team science. Four main facilitating factors and strategies for success emerged: (1) beneficial attitudes and beliefs about TD research and team science; (2) effective team processes; (3) brokering and bridge-building activities by individuals holding particular roles in a research center; and (4) funding initiative characteristics that support TD team science. Broad impacts of participating in TD team science in the context of TREC I included: (1) new positive attitudes about TD research and team science; (2) new boundary-crossing collaborations; (3) scientific advances related to research approaches, findings, and dissemination; (4) institutional culture change and resource creation in support of TD team science; and (5) career advancement. Funding agencies, academic institutions, and scholarly journals can help to foster TD team science through funding opportunities, institutional policies on

  13. Construction of a Bacterial Cell that Contains Only the Set of Essential Genes Necessary to Impart Life

    Science.gov (United States)

    2014-11-11

    viable, with a reasonable growth rate o The M. mycoides genome has been reduced to 721,860 bp using the Tandem Repeat Endonuclease Cleavage (TREC...by restriction analysis: Figure 9 Figure 9. Restriction analysis of Cluster 33 deletion from Clone 48. Two replicates from each of...three yeast isolates (39, 40, 42) were transplanted and analyzed by restriction with BssHII and SmaI. Digestion with BssHII produced the

  14. La evaluación de creencias y actitudes disfuncionales en los modelos de Ellis y Beck: similitudes y diferencias

    OpenAIRE

    Ruiz Rodríguez, José; Fusté Escolano, Adela

    2015-01-01

    El objetivo del presente estudio es el análisis comparativo del 'Inventario de Actitudes y Creencias' (ABI) y la 'Escala de Actitudes Disfuncionales' (DAS) elaborados, respectivamente, desde las perspectivas de la Terapia Racional Emotivo Conductual (TREC) de Albert Ellis y la Terapia Cognitiva (TC) de Aaron Beck. Administramos sendos cuestionarios a una muestra de 156 estudiantes universitarios y verificamos la correspondencia y covariancia entre escalas mediante análisis de correlación de S...

  15. T-cell receptor and K-deleting recombination excision circles in newborn screening of T- and B-cell defects: review of the literature and future challenges

    Directory of Open Access Journals (Sweden)

    Marco Chiarini

    2013-05-01

    Full Text Available Since its introduction as a public health programme in the United States in the early 1960s, newborn blood screening (NBS has evolved from the detection of phenylalanine levels on filter paper to the application of DNA-based technologies to identify T-cell lymphopenia in infants with severe combined immunodeficiency. This latter use of NBS has required the development of an assay for T-cell lymphopenia based on the quantification of T-cell receptor excision circles (TRECs that could be performed on dried blood spots routinely collected from newborn infants. The TREC-based NBS was developed six years ago, and there have already been 7 successful pilot studies since then. Similarly, efforts are now being made to establish a screen for B-cell defects, in particular agammaglobulinaemia, taking advantage of the introduction of the method for the quantification of K-deleting recombination excision circles (KRECs. A further achievement of NBS could be the simultaneous recognition of T- and B-cell defects using the combined quantification of TRECs and KRECs from Guthrie card blood spots. This approach may help the early identification of infants with T- and B-cell deficiencies so that they can then be referred to specialised paediatric centres, where a precise diagnosis of severe combined immunodeficiency and agammaglobulinaemia can be performed, and where then they can immediately receive specific therapy. Simultaneous TREC and KREC quantification should also allow classification of patients into subgroups and help identify children with less serious primary immunodeficiencies. This would help avoid the opportunistic infections and frequent hospitalisations that result from a late or lack of diagnosis.

  16. A Hybrid Approach to Clinical Question Answering

    Science.gov (United States)

    2014-11-01

    participation in TREC, we submitted a single run using a hybrid Natural Language Processing ( NLP )-driven approach to accomplish the given task. Evaluation re...for the CDS track uses a variety of NLP - based techniques to address the clinical questions provided. We present a description of our approach, and...discuss our experimental setup, results and eval- uation in the subsequent sections. 2 Description of Our Approach Our hybrid NLP -driven method presents a

  17. Caterpillars and fungal pathogens: two co-occurring parasites of an ant-plant mutualism.

    Directory of Open Access Journals (Sweden)

    Olivier Roux

    Full Text Available In mutualisms, each interacting species obtains resources from its partner that it would obtain less efficiently if alone, and so derives a net fitness benefit. In exchange for shelter (domatia and food, mutualistic plant-ants protect their host myrmecophytes from herbivores, encroaching vines and fungal pathogens. Although selective filters enable myrmecophytes to host those ant species most favorable to their fitness, some insects can by-pass these filters, exploiting the rewards supplied whilst providing nothing in return. This is the case in French Guiana for Cecropia obtusa (Cecropiaceae as Pseudocabima guianalis caterpillars (Lepidoptera, Pyralidae can colonize saplings before the installation of their mutualistic Azteca ants. The caterpillars shelter in the domatia and feed on food bodies (FBs whose production increases as a result. They delay colonization by ants by weaving a silk shield above the youngest trichilium, where the FBs are produced, blocking access to them. This probable temporal priority effect also allows female moths to lay new eggs on trees that already shelter caterpillars, and so to occupy the niche longer and exploit Cecropia resources before colonization by ants. However, once incipient ant colonies are able to develop, they prevent further colonization by the caterpillars. Although no higher herbivory rates were noted, these caterpillars are ineffective in protecting their host trees from a pathogenic fungus, Fusarium moniliforme (Deuteromycetes, that develops on the trichilium in the absence of mutualistic ants. Therefore, the Cecropia treelets can be parasitized by two often overlooked species: the caterpillars that shelter in the domatia and feed on FBs, delaying colonization by mutualistic ants, and the fungal pathogen that develops on old trichilia. The cost of greater FB production plus the presence of the pathogenic fungus likely affect tree growth.

  18. Creating a 21st Century Community through the Teacher Research Experience (Invited)

    Science.gov (United States)

    Wilkening, E.; Beine, H. J.

    2009-12-01

    In the spring of 2009, I participated in PolarTREC - Teachers and Researchers Exploring and Collaborating, a Teacher Research Experience (TRE) funded by the National Science Foundation and managed by the Arctic Research Consortium of the United States. I assisted in hands-on research being performed by scientists with OASIS (Ocean, Atmosphere, Sea Ice and Snowpack) during their field campaign in Barrow, Alaska. Although I was in the field for only 3 weeks, it was merely a beginning to a transformation that took place not only in me, but also among all of those involved. The PolarTREC program embodies the principles fundamental to the 21st Century skill-set that we want our students to possess. The job market is changing for graduates, and education is striving to provide students with the skills necessary to thrive in the future. To ensure the success of students the International Society for Technology Education (ISTE) has defined 21st Century Skills. They are incorporated into many educational standards (such as the Arizona Educational Technology Standards) and they are practiced by the teachers, researchers, students and the PolarTREC community. They are: Creativity and Innovation Communication and Collaboration Research and Information Literacy Critical Thinking, Problem Solving, and Decision Making Digital Citizenship Technology Operations and Concepts

  19. Improved localization of cellular membrane receptors using combined fluorescence microscopy and simultaneous topography and recognition imaging

    Energy Technology Data Exchange (ETDEWEB)

    Duman, M; Pfleger, M; Chtcheglova, L A; Neundlinger, I; Bozna, B L; Ebner, A; Schuetz, G J; Hinterdorfer, P [Institute for Biophysics, University of Linz, Altenbergerstrasse 69, A-4040 Linz (Austria); Zhu, R; Mayer, B [Christian Doppler Laboratory for Nanoscopic Methods in Biophysics, Institute for Biophysics, University of Linz, Altenbergerstrasse 69, A-4040 Linz (Austria); Rankl, C; Moertelmaier, M; Kada, G; Kienberger, F [Agilent Technologies Austria GmbH, Aubrunnerweg 11, A-4040 Linz (Austria); Salio, M; Shepherd, D; Polzella, P; Cerundolo, V [Cancer Research UK Tumor Immunology Group, Weatherall Institute of Molecular Medicine, Nuffield Department of Medicine, University of Oxford, Oxford OX3 9DS (United Kingdom); Dieudonne, M, E-mail: ferry_kienberger@agilent.com [Agilent Technologies Belgium, Wingepark 51, Rotselaar, AN B-3110 (Belgium)

    2010-03-19

    The combination of fluorescence microscopy and atomic force microscopy has a great potential in single-molecule-detection applications, overcoming many of the limitations coming from each individual technique. Here we present a new platform of combined fluorescence and simultaneous topography and recognition imaging (TREC) for improved localization of cellular receptors. Green fluorescent protein (GFP) labeled human sodium-glucose cotransporter (hSGLT1) expressed Chinese Hamster Ovary (CHO) cells and endothelial cells (MyEnd) from mouse myocardium stained with phalloidin-rhodamine were used as cell systems to study AFM topography and fluorescence microscopy on the same surface area. Topographical AFM images revealed membrane features such as lamellipodia, cytoskeleton fibers, F-actin filaments and small globular structures with heights ranging from 20 to 30 nm. Combined fluorescence and TREC imaging was applied to detect density, distribution and localization of YFP-labeled CD1d molecules on {alpha}-galactosylceramide ({alpha}GalCer)-loaded THP1 cells. While the expression level, distribution and localization of CD1d molecules on THP1 cells were detected with fluorescence microscopy, the nanoscale distribution of binding sites was investigated with molecular recognition imaging by using a chemically modified AFM tip. Using TREC on the inverted light microscope, the recognition sites of cell receptors were detected in recognition images with domain sizes ranging from {approx} 25 to {approx} 160 nm, with the smaller domains corresponding to a single CD1d molecule.

  20. Low thymic output in the 22q11.2 deletion syndrome measured by CCR9+CD45RA+ T cell counts and T cell receptor rearrangement excision circles

    DEFF Research Database (Denmark)

    Lima, K; Abrahamsen, Gitte Meldgaard; Foelling, I

    2010-01-01

    Thymic hypoplasia is a frequent feature of the 22q11.2 deletion syndrome, but we know little about patients' age-related thymic output and long-term consequences for their immune system. We measured the expression of T cell receptor rearrangement excision circles (TREC) and used flow cytometry...... for direct subtyping of recent thymic emigrant (RTE)-related T cells in 43 patients (aged 1-54 years; median 9 years) from all over Norway and in age-matched healthy controls. Thymic volumes were estimated by ultrasound in patients. TREC levels correlated well with RTE-related T cells defined by co......-expression of CD3, CD45RA and CCR9 (r=0.84) as well as with the CD4+ and CD8+ T cell subtypes. RTE-related T cell counts also paralleled age-related TREC reductions. CD45RA+ T cells correlated well with absolute counts of CD4+ (r=0.87) and CD8+ (r=0.75) RTE-related T cells. Apart from CD45RA- T cells, all T cell...

  1. PID comes full circle: Applications of V(DJ recombination excision circles in research, diagnostics and newborn screening of primary immunodeficiency disorders

    Directory of Open Access Journals (Sweden)

    Menno C. Van Zelm

    2011-05-01

    Full Text Available The vast majority of patients suffering from a primary immunodeficiency (PID have defects in their T- and/or B-cell compartments. Despite advances in molecular diagnostics, in many patients no underlying genetic defect has been identified. B- and T-lymphocytes are unique in their ability to create a receptor by genomic rearrangement of their antigen receptor genes via V(DJ recombination. During this process, stable circular excision products are formed that do not replicate when the cell proliferates. Excision circles can be reliably quantified using real-time quantitative (RQ-PCR techniques. Frequently occurring δREC–ψJα T-cell receptor excision circles (TRECs have been used to assess thymic output and intronRSS–Kde recombination excision circles (KREC to quantify B-cell replication history. In this perspective, we describe how TRECs and KRECs are formed during precursor- T and B cell differentiation, respectively. Furthermore, we discuss new insights obtained with TRECs and KRECs and specifically how these excision circles can be applied to support therapy monitoring, patient classification and newborn screening of PID.

  2. Hypermethylation of FOXP3 Promoter and Premature Aging of the Immune System in Female Patients with Panic Disorder?

    Science.gov (United States)

    Prelog, Martina; Hilligardt, Deborah; Schmidt, Christian A; Przybylski, Grzegorz K; Leierer, Johannes; Almanzar, Giovanni; El Hajj, Nady; Lesch, Klaus-Peter; Arolt, Volker; Zwanzger, Peter; Haaf, Thomas; Domschke, Katharina

    2016-01-01

    Immunological abnormalities associated with pathological conditions, such as higher infection rates, inflammatory diseases, cancer or cardiovascular events are common in patients with panic disorder. In the present study, T cell receptor excision circles (TRECs), Forkhead-Box-Protein P3 gene (FOXP3) methylation of regulatory T cells (Tregs) and relative telomere lengths (RTLs) were investigated in a total and subsamples of 131 patients with panic disorder as compared to 131 age- and sex-matched healthy controls in order to test for a potential dysfunction and premature aging of the immune system in anxiety disorders. Significantly lower TRECs (p = 0.004) as well as significant hypermethylation of the FOXP3 promoter region (p = 0.005) were observed in female (but not in male) patients with panic disorder as compared to healthy controls. No difference in relative telomere length was discerned between patients and controls, but significantly shorter telomeres in females, smokers and older persons within the patient group. The presently observed reduced TRECs in panic disorder patients and FOXP3 hypermethylation in female patients with panic disorder potentially reflect impaired thymus and immunosuppressive Treg function, which might partly account for the known increased morbidity and mortality of anxiety disorders conferred by e.g. cancer and cardiovascular disorders.

  3. Palynological reconstruction of the rain forest in French Guiana during the past 3000 years; Reconstitution palynologique de la foret guyanaise au cours des 3000 dernieres annees

    Energy Technology Data Exchange (ETDEWEB)

    Ledru, M.P.; Fournier, M.; Martin, L. [ORSTOM, 93 - Bondy (France); Charles-Dominique, P.; Riera, B. [Laboratoire d`ecologie generale, URA, CNRS, 91 - Brunoy (France); Tardy, Ch. [Laboratoire de paleobotanique, URA, CNRS, Institut de botanique 34 - Montpellier (France)

    1997-03-01

    Pollen analysis has been carried out on a core drilled in a peaty palm swamp forest in the rain forest of French Guiana. This has brought new data on the variations of the forest cover during the past 3000 years. Momentary peaks of the pioneer species Cecropia frequency give evidence of two phases of relatively open vegetation: on between 2124 - 1679 and 1525 - 1375 calibrated years B.P. and another shorter one around 658-424 yrs B.P. cal. The first one appears to be due to the combined incidence of a dry climatic period and of forest fires of human origins. (authors). 13 refs.

  4. Long-range correlations in rectal temperature fluctuations of healthy infants during maturation.

    Directory of Open Access Journals (Sweden)

    Georgette Stern

    Full Text Available BACKGROUND: Control of breathing, heart rate, and body temperature are interdependent in infants, where instabilities in thermoregulation can contribute to apneas or even life-threatening events. Identifying abnormalities in thermoregulation is particularly important in the first 6 months of life, where autonomic regulation undergoes critical development. Fluctuations in body temperature have been shown to be sensitive to maturational stage as well as system failure in critically ill patients. We thus aimed to investigate the existence of fractal-like long-range correlations, indicative of temperature control, in night time rectal temperature (T(rec patterns in maturing infants. METHODOLOGY/PRINCIPAL FINDINGS: We measured T(rec fluctuations in infants every 4 weeks from 4 to 20 weeks of age and before and after immunization. Long-range correlations in the temperature series were quantified by the correlation exponent, alpha using detrended fluctuation analysis. The effects of maturation, room temperature, and immunization on the strength of correlation were investigated. We found that T(rec fluctuations exhibit fractal long-range correlations with a mean (SD alpha of 1.51 (0.11, indicating that T(rec is regulated in a highly correlated and hence deterministic manner. A significant increase in alpha with age from 1.42 (0.07 at 4 weeks to 1.58 (0.04 at 20 weeks reflects a change in long-range correlation behavior with maturation towards a smoother and more deterministic temperature regulation, potentially due to the decrease in surface area to body weight ratio in the maturing infant. alpha was not associated with mean room temperature or influenced by immunization CONCLUSIONS: This study shows that the quantification of long-range correlations using alpha derived from detrended fluctuation analysis is an observer-independent tool which can distinguish developmental stages of night time T(rec pattern in young infants, reflective of maturation of

  5. Revolutionizing Climate Science: Using Teachers as Communicators

    Science.gov (United States)

    Warburton, J.; Crowley, S.; Wood, J.

    2012-12-01

    PolarTREC (Teachers and Researchers Exploring and Collaborating) is a National Science Foundation (NSF) funded program in which K-12 teachers participate in hands-on field research experiences in the Polar Regions. Teachers are the dynamic conduits for communicating climate science. In the PolarTREC final report, researchers found that teachers were vital in refining the language of their science and have shaped the goals of the scientific project. Program data demonstrates that science in classrooms is better understood when teachers have a full-spectrum grasp of project intricacies from defining the project, to field data collection, encountering situations for creativity and critical thinking, as well as participating in data and project analysis. Teachers' translating the authentic scientific process is integral in communicating climate science to the broader public. Teachers playing a major role in polar science revolutionize the old paradigm of "in-school learning". Through daily online journaling and forums, social media communication, live webinars with public, and professional development events, these teachers are moving beyond classrooms to communicate with society. Through teachers, climate policy can be shaped for the future by having scientifically literate students as well as assessable science. New paradigms come as teachers attain proficient levels of scientific understanding paired with the expert abilities for communication with years of experience. PolarTREC teachers are a model for new interactions peer-to-peer learning and mentorship for young scientists. Our programmatic goal is to expand the opportunities for PolarTREC teachers to share their involvement in science with additional formal and informal educators. 'Teaching the teachers' will reach exponential audiences in media, policy, and classrooms. Modeling this program, we designed and conducted a teacher training on climate science in Denali National Park. Utilizing expert university

  6. Walk the Talk: Teachers as Leaders in Climate Change Education

    Science.gov (United States)

    Warburton, J.; Bartholow, S.; Larson, A.

    2014-12-01

    The notion of teachers as leaders and communicators is not new but rather it has been limited in scope. Teachers have long served as team leaders, department chairs, and curriculum developers. But what happens when you go beyond these typical roles in professional development? Can teachers become lead communicators beyond the classroom? Can they become leaders of change on important topics like the climate? For nearly a decade, PolarTREC (Teachers and Researchers Exploring and Collaborating), funded by the National Science Foundation, has been teaming teachers with research projects in all fields of polar science. Teachers participate in hands-on field research experiences in the polar regions which focus heavily on climate change and climate science. Administrated by the Arctic Research Consortium of the United States, the goal of PolarTREC is to invigorate polar science education and understanding by bringing K-12 educators and polar researchers together. The program fosters a teacher and researcher network, which accelerates the cross-pollination of knowledge in science practices, findings, and classroom implementation throughout disciplines. Evaluation data exposes a crucial dynamic that increases the potential for a successful climate change science campaign. Data indicates that teachers can tackle challenges such as reframing climate change science to better address the need for a particular campaign, as well as garnering the science project the necessary support through effective, authentic, and tangible communication efforts to policymakers, funders, students, and the public. Researchers reported the value of explaining their science, in-situ, allowed them to reframe and rework the objectives of the science project to attain meaningful outcomes. More than half of the researchers specifically noted that one of the strengths of the PolarTREC project is its benefit to the scientific process. The researchers also viewed PolarTREC as an essential outreach

  7. Defining combined immunodeficiency.

    Science.gov (United States)

    Roifman, Chaim M; Somech, Raz; Kavadas, Fotini; Pires, Linda; Nahum, Amit; Dalal, Ilan; Grunebaum, Eyal

    2012-07-01

    Although the extreme condition of typical profound T-cell dysfunction (TD), severe combined immunodeficiency (SCID), has been carefully defined, we are currently in the process of better defining less typical T-cell deficiencies, which tend to present with autologous circulating T-cell combined immunodeficiency (CID). Because autologous cells might interfere with the outcome of bone marrow transplantation, protocols usually include conditioning regimens. Therefore it is important to define the numbers of autologous cells usually detected in patients with CID versus those with SCID. We sought to determine the number of circulating T cells in patients with SCID as opposed to those with CID, to study their function, and to evaluate their possible detection during newborn screening using T-cell receptor excision circle (TREC) analysis. Numbers of circulating CD3(+) T cells (as determined by means of flow cytometry), in vitro responses to PHA, and TREC levels, all measured at presentation, were compiled from the research charts of the entire cohort of patients followed prospectively for T-cell immunodeficiency at the Hospital for Sick Children. Clinical data were ascertained retrospectively from the patient's hospital charts. One hundred three patients had CD3(+) determinations, and 80 of them had a genetic diagnosis. All patients considered to have typical SCID had CD3(+) T-cell counts of fewer than 500 cells/μL. Some variability was observed among different genotypes. In vitro responses to PHA were recorded in 88 patients, of whom 68 had a genetic diagnosis. All patients with low CD3(+) T-cell numbers (<500 cells/μL) also had markedly decreased responses to PHA (typical SCIDs). However, responses ranged widely in the groups of patients with TD who had more than 500 CD3(+) autologous circulating T cells per microliter. Although patients with Omenn syndrome and ζ chain-associated protein, 70 kDa (ZAP70), and purine nucleoside phosphorylase (PNP) deficiencies had low

  8. Necessity of Removing American Football Uniforms From Humans With Hyperthermia Before Cold-Water Immersion.

    Science.gov (United States)

    Miller, Kevin C; Long, Blaine C; Edwards, Jeffrey

    2015-12-01

    The National Athletic Trainers' Association and the American College of Sports Medicine have recommended removing American football uniforms from athletes with exertional heat stroke before cold-water immersion (CWI) based on the assumption that the uniform impedes rectal temperature (T(rec)) cooling. Few experimental data exist to verify or disprove this assumption and the recommendations. To compare CWI durations, T(rec) cooling rates, thermal sensation, intensity of environmental symptoms, and onset of shivering when hyperthermic participants wore football uniforms during CWI or removed the uniforms immediately before CWI. Crossover study. Laboratory. Eighteen hydrated, physically active men (age = 22 ± 2 years, height = 182.5 ± 6.1 cm, mass = 85.4 ± 13.4 kg, body fat = 11% ± 5%, body surface area = 2.1 ± 0.2 m(2)) volunteered. On 2 days, participants exercised in the heat (approximately 40°C, approximately 40% relative humidity) while wearing a full American football uniform (shoes; crew socks; undergarments; shorts; game pants; undershirt; shoulder pads; jersey; helmet; and padding over the thighs, knees, hips, and tailbone [PADS]) until T(rec) reached 39.5°C. Next, participants immersed themselves in water that was approximately 10°C while wearing either undergarments, shorts, and crew socks (NOpads) or PADS without shoes until Trec reached 38°C. The CWI duration (minutes) and T(rec) cooling rates (°C/min). Participants had similar exercise times (NOpads = 40.8 ± 4.9 minutes, PADS = 43.2 ± 4.1 minutes; t(17) = 2.0, P = .10), hypohydration levels (NOpads = 1.5% ± 0.3%, PADS = 1.6% ± 0.4%; t(17) = 1.3, P = .22), and thermal-sensation ratings (NOpads = 7.2 ± 0.3, PADS = 7.1 ± 0.5; P > .05) before CWI. The CWI duration (median [interquartile range]; NOpads = 6.0 [5.4] minutes, PADS = 7.3 [9.8] minutes; z = 2.3, P = .01) and T(rec) cooling rates (NOpads = 0.28°C/min ± 0.14°C/min, PADS = 0.21°C/min ± 0.11°C/min; t(17) = 2.2, P = .02) differed

  9. Late Holocene paleoenvironments of the floodplain of the Solimões River, Central Amazonia, based on the palynological record of Lake Cabaliana

    Directory of Open Access Journals (Sweden)

    Natália de Paula Sá

    Full Text Available ABSTRACT The core PD-67 of 160 cm depth was collected from the delta of Lake Cabaliana situated on the Solimões River. Seventeen samples were removed for palynological and sedimentological analysis and three for radiocarbon analysis. Two dry periods, both in the Late Holocene, were observed (2800-2550 cal yr BP, 1450-550 cal yr BP separated by a wetter phase (2550-1450 cal yr BP. In 2800-2550 cal yr BP, varzea forests of Alchornea, Symmeria, Cecropia, Alternanthera and Asteraceae were predominant. Beginning in 2,550-1450 cal yr BP, the varzea was characterized by pioneer elements, such as Cassia, Laetia, Mabea, Symmeria and Cecropia, and by the expansion of Poaceae, Cyperaceae, Sagittaria, Montrichardia and Asteraceae. In 1450-550 cal yr BP the succession of varzea continued with Pseudobombax, Laetia, Luehea/Lueheopsis and Ryanaea increasing simultaneously with the terra firme vegetation of Rutaceae, Sapotaceae, Styrax, Scleronema, Anthurium, Araceae, pteridophytes and Pariana. The successional dynamics at Lake Cabaliana indicated that the local varzea had become established recently, and is composed of a mosaic of different successional stages of vegetation influenced mainly by flood pulse and variation in rainfall. It is therefore possible to propose that the recent climate history of Central Amazonia reflects changes in rainfall patterns in the basin.

  10. Florística e estrutura de fragmento florestal em área de transição na Amazônia Matogrossense no município de Sinop Floristics and structure of a forest fragment at a transitional zone at the Amazon in Mato Grosso State, Municipality of Sinop

    Directory of Open Access Journals (Sweden)

    Rosalia de Aguiar Araujo

    2009-01-01

    Full Text Available A fragmentação do ambiente é intensa na amazônia matogrossense e é esperado como consequência, além do desaparecimento da vegetação original, que a flora dos fragmentos seja transicional, com elementos de floresta amazônica e de cerrado e que já apresentem elevada presença de famílias e espécies pioneiras. Este trabalho objetivou avaliar a composição florística e obter parâmetros fitossociológicos de componentes arbóreos presentes em um fragmento urbano no município de Sinop, Mato Grosso com vistas a confirmar sua classificação como vegetação de transição e detectar indícios de perturbação pela fragmentação. A vegetação foi amostrada pela instalação de 25 parcelas permanentes de 20 x 20m, onde foram amostrados os indivíduos com CAP igual ou superior a 15 cm à altura de 1,30m do solo. A densidade total da área foi de 1555 ind./ha, distribuídos em 37 famílias botânicas, 81 gêneros e 113 espécies. A família mais representativa foi Leguminosae com 14 espécies. As espécies que mais contribuíram em abundância e apresentaram maior frequência foram: Cecropia sciadophylla, Cecropia sp., Bellucia grossularioides e Vismia guianensis. O índice de Shannon (H' foi de 3,55, considerado alto para uma floresta de transição. A equabilidade de Pielou foi de 0,75, sugerindo grande dominância de poucas espécies. As espécies que mais se destacaram em ordem decrescente de VI (% foram Cecropia sp., Bellucia grossularioides, Qualea ingens, Cecropia sciadophylla, Vismia guianensis, Miconia prasina, Trattinickia burserifolia, Unonopsis guatterioides e Schefflera vinosa. O remanescente apresenta uma flora mista amazônica e de cerrado, confirmando ser ecótono e a abundância de pioneiras sugere distúrbios. Esta floresta protege espécies madeireiras e frutíferas com grande potencial para uso múltiplo, podendo ser um espaço educativo com vistas a conservação e manejo sustentável.Fragmentation is intense in

  11. Late Holocene rainforest disturbance in French Guiana.

    Science.gov (United States)

    Ledru, M -P.

    2001-06-01

    Palm swamp forest sediments collected in French Guiana provide new data about late Holocene rainforest. Two cores were collected in 'Les Nouragues' ecological station (4 degrees 05'N, 52 degrees 40'W). The lithology shows two different types of sediment, organic peat in the upper part and oxidized clay with low organic content and lacking pollen in the lower part, both separated by a gravel horizon. Radiocarbon dates show that this gravel horizon could have been deposited between 4500 and 3000yrBP. Pollen analysis carried out on the organic sediments record rainforest disturbances between ca 1520-1380 and 1060-860cal yrBP suggested by the presence of the pioneer tree species Cecropia together with other shade intolerant genera. Cecropia is recorded for a period that lasts between 660 and 320 years. This abnormal duration for presence of a pioneer species in rainforest is explained by brief and repeated changes in the composition of the canopy asssociated to perturbations of the palm swamp.

  12. A liquid chromatography-atmospheric pressure photoionization tandem mass spectrometric (LC-APPI-MS/MS) method for the determination of triterpenoids in medicinal plant extracts.

    Science.gov (United States)

    Gobo, Luciana Assis; Viana, Carine; Lameira, Osmar Alves; de Carvalho, Leandro Machado

    2016-08-01

    An analytical method using liquid chromatography-atmospheric pressure photoionization tandem mass spectrometry with toluene as a dopant was developed for the determination of triterpenes in medicinal plant extracts. The 12 compounds determined have been shown to exhibit biological activity, such as gastroprotective, hepatoprotective, anti-inflammatory, antiviral and anti-tumor effects. The parameters of the atmospheric pressure photoionization interface were optimized to obtain the highest possible sensitivity for all of the compounds. The limits of detection and quantification ranged from 0.4 to 157.9 µg l -1 and 1.3 to 526.4 µg l -1 , respectively. The method was validated and applied to extracts of five medicinal plants species (Mansoa alliacea (Lam.) A.H.Gentry, Bauhinia variegata var variegata, Bauhinia variegata var alboflava, Cecropia obtuse Trécul and Cecropia palmate Willd) from the Amazonian region. The concentrations of the six triterpenes quantified in the samples ranged from 0.424 mg kg -1 for ursolic acid to 371.96 mg kg -1 for β-amyrin, which were quantified by using the standard addition method (n = 3). Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  13. Improving Broader Impacts through Researcher-Educator Partnerships

    Science.gov (United States)

    Timm, K.; Warburton, J.; Larson, A. M.

    2009-12-01

    Since 1998, the Arctic Research Consortium of the United States (ARCUS) has designed and implemented successful Teacher Research Experience (TRE) programs enabling teachers to work directly with polar scientists in the field and bring their experience back to their classrooms and communities. The PolarTREC TRE model, administered during the International Polar Year (2007-2009), is most effective, exhibiting far-reaching broader impacts when ideas are shared, each partners’ expertise is respected, and both work toward the common goal of delivering high-quality information. Between 2004 and 2009, ARCUS has selected, trained, and supported 77 teachers on polar teacher research experiences. Although a limited number of teachers are able to participate in a field experience, selected teachers have expertise in translating research approaches and results into widely shared learning tools and programs. Between 2007-2009, PolarTREC teachers have constructed nearly 100 classroom lesson plans and activities as a result of their experience. Selected teachers are usually well connected within their schools, communities, and professions, bringing the science to numerous followers during their expedition. Live events with teachers and researchers in the field have attracted over 11,000 participants, primarily K-12 students. The PolarTREC TRE Model includes numerous methods to support outreach activities while teachers and researchers are in the field. These include web-based communications, journals, discussion forums, multimedia, and live events—all easily replicable activities with the potential to affect large numbers of people. In addition, the TRE experience continues to produce broader impacts far into the future of the teacher and researcher’s careers through ongoing communications, presentations at professional conferences, and continued support of each other’s work through activities including classroom visits, joint proposal development, and much more

  14. Quality Climate Change Professional Development Translates into Quality Climate Change Education (Invited)

    Science.gov (United States)

    Holzer, M. A.

    2013-12-01

    Perhaps one of the reasons we have so many climate change deniers in the United States is that to them climate change is not occurring. This is a valid claim about climate change deniers considering that the effects of climate change in the mid-latitudes are quite subtle as compared to those found in low-latitude and high-latitude regions. A mid-latitude classroom teacher is saddled with the challenge of enlightening students about our changing climate and empowering students to assist in making necessary lifestyle changes, all the while the students don't understand the urgency in doing so. Quality climate change data and resources from the Polar Regions and low latitudes, as well as connections to researchers from these regions help to bridge the understanding of our changing climate from the extreme latitudes to the mid-latitudes. Connecting science teachers with data, resources, and researchers is one way of ensuring our mid-latitude students understand the urgency in taking appropriate actions to adapt, mitigate, and show resilience. This presentation will highlight a few of the many impacts of an authentic research experience for teachers that not only provides teachers with data, resources, and researchers, but changes the way a science teacher teaches where the methods they use mirror the methods used by scientists. National projects like PolarTREC connect educators with the science of climate change as well as the reality of impacts of climate change. For example, research expeditions in the Arctic and in Antarctica connect teachers with the content and practices of climate change science preparing them to replicate their experiences with their students. A PolarTREC experience does not end with the close of the expedition. Teachers continue their connections with the program through their educator network, the integration of PolarTREC resources into their curriculums, and communications with their principal investigators either virtually or with school

  15. An evaluation of the effectiveness of the Teachers and Researchers Exploring and Collaborating Professional Development Program

    Science.gov (United States)

    Kaden, Ute

    2007-12-01

    Research has shown that teachers' skills and knowledge are key determinants of students' opportunities to learn (Haycock, 2003). As highlighted in the National Science Education Standards (National Research Council, 1996) professional development must include experiences that engage teachers in active learning that builds their knowledge, understanding, and ability. The 2004 to 2006 Teacher and Researcher Exploring and Collaborating Professional Development Program (TREC) program funded by the National Science Foundation (NSF) and implemented by the Arctic Research Consortium of the United States (ARCUS) targeted well documented shortcomings in professional development by offering two to six weeks field research experiences in the Arctic Region for K-12 teachers as a collaborative approach between scientists and science teachers. This study described the extent of effectiveness of TREC with regard to teachers' abilities to teach science in terms of knowledge, attitudes, and skills and identified program components that were most effective. A mixed methods research design was used requiring the collection and systematic analysis of (1) archival data collected by the Arctic Research Consortium of the United States (ARCUS); and (2) participant survey. Data were analyzed and interpreted utilizing descriptive statistics, cross-tabulation and triangulation (Glaser & Strauss, 1967; Lincoln & Guba, 1985). The results of this study provides evidence that TREC was effective as a professional development program in refining science teachers' knowledge, skills, and confidence to teach science effectively, renewed their enthusiasm for teaching and promoted students' learning. Respondents reported that they introduced new topics in their science lessons, incorporated new hands-on activities, gave more emphasis to data collection, integrated more technology, assigned projects based on "real world" problems more frequently, and communicated the excitement of Polar research. The

  16. Influência da anestesia geral e bloqueio peribulbar em trabeculectomias: comparação visual e pressórica

    Directory of Open Access Journals (Sweden)

    Carlos Buhler

    2012-04-01

    Full Text Available OBJETIVO: Avaliar os resultados de trabeculectomias (TRECs com anestesia geral e bloqueio peribulbar, visando definir de forma indireta a influência das técnicas anestésicas no resultado da cirurgia. MÉTODOS: Foram analisados os prontuários de 25 pacientes com glaucoma não controlado submetidos à trabeculectomia (TREC, sendo 11 com anestesia geral e 14 com anestesia peribulbar. Foram incluídos somente pacientes pseudofácicos com glaucoma e sem outras patologias oculares como retinopatia diabética ou doença macular relacionada a idade. A acuidade visual (AV, pressão intraocultar (PIO, número de medicações utilizadas, além de dados demográficos foram coletados retrospectivamente com 7, 30, 6 meses e 1 ano de pós-operatório. RESULTADOS: Ambos os grupos foram semelhantes nos quesitos demográficos, onde não houve diferença estatisticamente significante entre idade, sexo e raça. Não foram encontradas diferenças significativas nas variáveis estudadas em todas as avaliações, com significância estatística (p<0,05. CONCLUSÃO: Não encontramos diferenças entre os resultados de TRECs com anestesia geral e com bloqueio peribulbar, porém mais estudos com um número maior de pacientes são necessários para comprovar este achado.

  17. RAG1 deficiency may present clinically as selective IgA deficiency.

    Science.gov (United States)

    Kato, Tamaki; Crestani, Elena; Kamae, Chikako; Honma, Kenichi; Yokosuka, Tomoko; Ikegawa, Takeshi; Nishida, Naonori; Kanegane, Hirokazu; Wada, Taizo; Yachie, Akihiro; Ohara, Osamu; Morio, Tomohiro; Notarangelo, Luigi D; Imai, Kohsuke; Nonoyama, Shigeaki

    2015-04-01

    Recombination-activating gene (RAG) 1 and 2 deficiency is seen in patients with severe combined immunodeficiency (SCID) and Omenn syndrome. However, the spectrum of the disease has recently expanded to include a milder phenotype. We analyzed a 4-year-old boy who was initially given the diagnosis of selective immunoglobulin A deficiency (SIgAD) based on immunoglobulin serum levels without any opportunistic infections, rashes, hepatosplenomegaly, autoimmunity or granulomas. The patient was found to be infected with varicella zoster; however, the clinical course was not serious. He produced antiviral antibodies. We performed lymphocyte phenotyping, quantification of T cell receptor excision circles (TRECs) and kappa deleting recombination excision circles (KRECs), an analysis of target sequences of RAG1 and 2, a whole-genome SNP array, an in vitro V(D)J recombination assay, a spectratype analysis of the CDR3 region and a flow cytometric analysis of the bone marrow. Lymphocyte phenotyping demonstrated that the ratio of CD4+ to CD8+ T cells was inverted and the majority of CD4+T cells expressed CD45RO antigens in addition to the almost complete lack of B cells. Furthermore, both TRECs and KRECs were absent. Targeted DNA sequencing and SNP array revealed that the patient carried a deletion of RAG1 and RAG2 genes on the paternally-derived chromosome 11, and two maternally-derived novel RAG1 missense mutations (E455K, R764H). In vitro analysis of recombination activity showed that both RAG1 mutant proteins had low, but residual function. The current case further expands the phenotypic spectrum of mild presentations of RAG deficiency, and suggests that TRECs and KRECs are useful markers for detecting hidden severe, as well as mild, cases.

  18. Rhetorical relations for information retrieval

    DEFF Research Database (Denmark)

    Lioma, Christina; Larsen, Birger; Lu, Wei

    2012-01-01

    -called discourse structure has been applied successfully to several natural language processing tasks. This work studies the use of rhetorical relations for Information Retrieval (IR): Is there a correlation between certain rhetorical relations and retrieval performance? Can knowledge about a document’s rhetorical...... relations be useful to IR? We present a language model modification that considers rhetorical relations when estimating the relevance of a document to a query. Empirical evaluation of different versions of our model on TREC settings shows that certain rhetorical relations can benefit retrieval effectiveness...

  19. A Part-Of-Speech term weighting scheme for biomedical information retrieval.

    Science.gov (United States)

    Wang, Yanshan; Wu, Stephen; Li, Dingcheng; Mehrabi, Saeed; Liu, Hongfang

    2016-10-01

    In the era of digitalization, information retrieval (IR), which retrieves and ranks documents from large collections according to users' search queries, has been popularly applied in the biomedical domain. Building patient cohorts using electronic health records (EHRs) and searching literature for topics of interest are some IR use cases. Meanwhile, natural language processing (NLP), such as tokenization or Part-Of-Speech (POS) tagging, has been developed for processing clinical documents or biomedical literature. We hypothesize that NLP can be incorporated into IR to strengthen the conventional IR models. In this study, we propose two NLP-empowered IR models, POS-BoW and POS-MRF, which incorporate automatic POS-based term weighting schemes into bag-of-word (BoW) and Markov Random Field (MRF) IR models, respectively. In the proposed models, the POS-based term weights are iteratively calculated by utilizing a cyclic coordinate method where golden section line search algorithm is applied along each coordinate to optimize the objective function defined by mean average precision (MAP). In the empirical experiments, we used the data sets from the Medical Records track in Text REtrieval Conference (TREC) 2011 and 2012 and the Genomics track in TREC 2004. The evaluation on TREC 2011 and 2012 Medical Records tracks shows that, for the POS-BoW models, the mean improvement rates for IR evaluation metrics, MAP, bpref, and P@10, are 10.88%, 4.54%, and 3.82%, compared to the BoW models; and for the POS-MRF models, these rates are 13.59%, 8.20%, and 8.78%, compared to the MRF models. Additionally, we experimentally verify that the proposed weighting approach is superior to the simple heuristic and frequency based weighting approaches, and validate our POS category selection. Using the optimal weights calculated in this experiment, we tested the proposed models on the TREC 2004 Genomics track and obtained average of 8.63% and 10.04% improvement rates for POS-BoW and POS

  20. Association between larger thymic size and higher thymic output in human immunodeficiency virus-infected patients receiving highly active antiretroviral therapy

    DEFF Research Database (Denmark)

    Kolte, L.; Dreves, A.-M.; Ersbøll, Annette Kjær

    2002-01-01

    To examine the impact of thymic size on immune recovery in patients with human immunodeficiency virus (HIV) infection, the thymus was visualized, using computed tomographic scans, in 25 HIV-infected patients who had received highly active antiretroviral therapy (HAART) for 6-18 months and had...... recovery was evaluated by determination of CD4+ T cell receptor repertoire in 19 of the HIV-infected patients. Larger thymic size was associated with higher CD4+ cell counts (r=0.498; P=.011) and higher CD4+ TREC frequency (r=0.652; P

  1. Assimilation of radar-based nowcast into HIRLAM NWP model

    DEFF Research Database (Denmark)

    Jensen, David Getreuer; Petersen, Claus; Rasmussen, Michael R.

    2015-01-01

    The present study introduces a nowcast scheme that assimilates radar extrapolation data (RED) into a nowcasting version of the high resolution limited area model (HIRLAM) numerical weather prediction (NWP) model covering the area of Denmark. The RED are based on the Co-TREC (tracking radar echoes...... by correlation) methodology and are generated from cleaned radar mosaics from the Danish weather radar network. The assimilation technique is a newly developed method that increases model precipitation by increasing low-level convergence and decreasing convergence aloft in order to increase the vertical velocity...

  2. Big River Reservoir Project - Pawcatuck River and Narragansett Bay Drainage Basins - Water and Related Land Resources Study. Volume III. Appendices H-K.

    Science.gov (United States)

    1981-07-01

    cover. To create a hedge and low growth for small mammals, the center stem of planted softwoods may be cut when the trec is 10 to 12 feet high. When...mixture would include field corn, buckwheat, millet, soybeans and perennial ryegrass. The amounts that should be planted on each half acre area are...Field corn 5.0 lbs Buckwheat 1.0 lb Millet 1.5 lbs Soybeans 1.5 lbs Perennial Ryegrass 1.0 lb 10.0 lbs 9 3.1.7.2 Fruit Bearing Trees and Shrubs Another

  3. PolarTREC—A Model Program for Taking Polar Literacy into the Future

    Science.gov (United States)

    Warburton, J.; Timm, K.; Larson, A. M.

    2009-12-01

    Polar TREC—Teachers and Researchers Exploring and Collaborating, is a three-year (2007-2009) NSF-funded International Polar Year (IPY) teacher professional development program that advances Science, Technology, Engineering, and Mathematics (STEM) education by improving teacher content knowledge and instructional practices through Teacher Research Experiences (TRE) in the Arctic and Antarctic. Leveraging profound changes and fascinating science taking place in the polar regions, PolarTREC broadly disseminates activities and products to students, educators, researchers, and the public, connecting them with the Arctic and Antarctica and sustaining the widespread interest in the polar regions and building on the enthusiasm that was generated through IPY. Central to the PolarTREC Teacher Research Experience Model, over 40 teachers have spent two to eight weeks participating in hands-on research in the polar regions and sharing their experiences with diverse audiences via live events, online multimedia journals, and interactive bulletin boards. The Connecting Arctic/Antarctic Researchers and Educators (CARE) Network unifies learning community members participants, alumni, and others, developing a sustainable association of education professionals networking to share and apply polar STEM content and pedagogical skills. Educator and student feedback from preliminary results of the program evaluation has shown that PolarTREC’s comprehensive program activities have many positive impacts on educators and their ability to teach science concepts and improve their teaching methods. Additionally, K-12 students polled in interest surveys showed significant changes in key areas including amount of time spent in school exploring research activities, importance of understanding science for future work, importance of understanding the polar regions as a person in today’s world, as well as increased self-reported knowledge and interest in numerous science content areas. Building

  4. Ellis y el Constructivismo: una perspectiva crítica sobre la Terapia Racional Emotivo Conductual

    OpenAIRE

    Ronald Toro

    2014-01-01

    El presente artículo de reflexión tuvo como objetivo abordar desde una postura crítica dos aspectos funda- mentales de la Terapia Racional Emotivo Conductual (TREC): la postura constructivista asumida por Ellis en sus últimos años y las nociones de irracionalidad según el modelo racionalista tradicional en psicotera- pia. Se tomó por lo tanto una posición en contra de las afirmaciones del padre de esta psicoterapia, quien sus- tentado en las nociones constructivistas radicales que afir...

  5. Thymic involvement in immune recovery during antiretroviral treatment of HIV infection in adults; comparison of CT and sonographic findings

    DEFF Research Database (Denmark)

    Kolte, Lilian; Strandberg, Charlotte; Dreves, Anne-Mette

    2002-01-01

    In adult HIV-infected patients, thymic size evaluated from CT scans seems to be important to the degree of immune reconstitution obtainable during treatment with highly active antiretroviral therapy (HAART). To examine whether ultrasound is as reliable as CT for estimating thymic size...... and predicting immune recovery, CT and ultrasound scans were performed in 25 adult HIV-infected patients and 10 controls. CD4 counts and naive CD4 counts were measured in order to determine immune reconstitution. Furthermore, the CD4+ T-cell receptor excision circle (TREC) frequency and T-cell receptor (TCR...

  6. The potential for use of semantic web technologies in IK management systems

    CSIR Research Space (South Africa)

    Fogwill, T

    2012-05-01

    Full Text Available in Sections 3 and 4. A prototype for an intelligent querying facility was developed, using a custom ontology developed for the IK themes of African Traditional Medicine and Food Security. This ontology was used to query annotated IK collected in the NIKMAS..., 2002. [22] E. Hovy, L. Gerber, U. Hermjakob, M. Junk, C. Lin, Question answering in Webclopedia. In: Proceedings of the Ninth Text REtrieval Conference (TREC-9), 2001, pp. 655-664. [23] V. Lopez, M. Pasin and E. Motta, AquaLog: An Ontology...

  7. Insect proteins as a potential source of antimicrobial peptides in livestock production

    DEFF Research Database (Denmark)

    Józefiak, A; Engberg, Ricarda Margarete

    2017-01-01

    Together with the extraction of first insect antimicrobial protein (AMP) from the pupae of the giant silk moths Hyalophora cecropia the antibacterial activity of insects was observed for the first time in 1980. Practically, AMPs are small, cationic proteins that exhibit activity against bacteria......, fungi as well as certain parasites and viruses. It is known that in addition to their antimicrobial effect, they boost host specific innate immune responses and exert selective immunomodulatory effects involved in angiogenesis and wound healing. More than 1,500 proteins with antimicrobial activity have...... cells. These characteristics contribute to the potential use of these proteins in human and veterinary medicine and in animal nutrition. Depending on their mode of action, insect AMPs may be applied as single peptides, as a complex of different AMPs and as an active fraction of insect proteins...

  8. Resistance of particleboard panels made of agricultural residues and bonded with synthetic resins or PVC plastic to wood-rotting fungi

    Directory of Open Access Journals (Sweden)

    Divino Eterno Teixeira

    2009-12-01

    Full Text Available This study aims to evaluate the resistance of three types of particleboard panel to biodeterioration, two of which bonded with synthetic resins and one bonded with PVC plastic. Composite panels were made using sugar cane straw particles as raw material which were bonded together with urea-formaldehyde (UF, tannin-formaldehyde (TANI and PVC plastic (PVC resins. Decay tests were performed following procedures outlined in the ASTM D2017-81/1994 standard, whereby sample specimens were subjected to attack by white rot fungus Trametes versicolor and brown rot fungus Gloeophyllum trabeum using pine (Pinus sp. and embaúba (Cecropia sp. as reference timber. Panels bonded with PVC resin were rated ‘resistant’ to attack by both fungi while those bonded with UF and TANI resins were rated ‘slightly resistant’ to their attack.

  9. Citogenética de Angiospermas coletadas em Pernambuco: V Cytogenetics of Angiosperms collected in the State of Pernambuco: V

    Directory of Open Access Journals (Sweden)

    Andrea Pedrosa

    1999-04-01

    Full Text Available Foram analisadas 33 espécies, entre nativas e introduzidas, pertencentes a 20 famílias de angiospermas ocorrentes no Estado de Pernambuco. A caracterização cariotípica da maioria das espécies foi baseada no número e morfologia cromossômica, padrão de condensação de cromossomos profásicos e estrutura de núcleo interfásico. Cinco espécies tiveram seus números cromossômicos determinados pela primeira vez, sendo elas: Cereus jamacaru (2n=22, Clitoria fairchildiana (2n=22, Eugenia luschnathiana (2n=22, Licania tomentosa (2n=22 e Spondias tuberosa (n=16. No caso de Licania tomentosa esta é a primeira citação de número cromossômico para o gênero. Das outras 28 espécies, três (Cecropia cf. palmata, 2n=26; Crinum erubescens, 2n=70; e Schinus terebentifolius, 2n=28 apresentaram números cromossômicos diferentes dos registrados previamente na literatura.Thirty three native and introduced species from 20 families of angiosperms collected in the State of Pernambuco were analysed. The karyotype description of the majority of the species was based on chromosome number and morphology, condensation pattern of prophase chromosomes as well as interphase nuclear structure. In five species (Cereus jamacaru, 2n=22; Clitoria fairchildiana, 2n=22; Eugenia luschnathiana, 2n=22; Licania tomentosa, 2n=22; and Spondias tuberosa, n=16 the chromosome number is reported here for the first time. In the case of Licania tomentosa, this is also the first report for the genus. Among the other 28 species, three (Cecropia cf. palmata, 2n=26; Crinum erubescens, 2n=70; and Schinus terebentifolius, 2n=28 showed chromosome numbers different from what has previously been reported.

  10. Botanical profile of bee pollen from the southern coastal region of Bahia, Brazil Perfil botânico do pólen apícola proveniente do litoral sul da Bahia, Brasil

    Directory of Open Access Journals (Sweden)

    Marcos da Costa Dórea

    2010-09-01

    Full Text Available This paper aims to identify the botanical origin of pollen loads collected by Apis mellifera L. in Canavieiras municipality, Bahia state. It provides a list of polliniferous plant species from the Atlantic Forest biome that are important for the development of regional apiculture. Using the acetolysis method, 35 bee-pollen samples were analyzed qualitatively and quantitatively. Results showed that pollen types Elaeis (23.99%, Mimosa pudica (22.78% and Cecropia (13.68% were the most abundant among the samples. These also showed the highest relative frequencies of the material studied and were important pollen sources for bees in the study area.O presente trabalho teve por objetivo identificar a origem botânica das bolotas de pólen coletadas pelas abelhas Apis mellifera L. no município de Canavieiras, Bahia, gerando uma lista de plantas poliníferas pertencentes ao bioma Mata Atlântica e importantes para o desenvolvimento da apicultura regional. Foram analisadas palinologicamente 35 amostras de pólen apícola, utilizando-se o processo de acetólise para, em seguida, serem feitas análises qualitativas e quantitativas. Os resultados revelaram que os tipos polínicos Elaeis (23,99%, Mimosa pudica (22,78% e Cecropia (13,68% foram os mais abundantes no pólen apícola analisado. Estes tipos polínicos também apresentaram as maiores frequências relativas de todo o material estudado e representam importantes plantas fontes de pólen para as abelhas na área estudada.

  11. A DYNAMIC FEATURE SELECTION METHOD FOR DOCUMENT RANKING WITH RELEVANCE FEEDBACK APPROACH

    Directory of Open Access Journals (Sweden)

    K. Latha

    2010-07-01

    Full Text Available Ranking search results is essential for information retrieval and Web search. Search engines need to not only return highly relevant results, but also be fast to satisfy users. As a result, not all available features can be used for ranking, and in fact only a small percentage of these features can be used. Thus, it is crucial to have a feature selection mechanism that can find a subset of features that both meets latency requirements and achieves high relevance. In this paper we describe a 0/1 knapsack procedure for automatically selecting features to use within Generalization model for Document Ranking. We propose an approach for Relevance Feedback using Expectation Maximization method and evaluate the algorithm on the TREC Collection for describing classes of feedback textual information retrieval features. Experimental results, evaluated on standard TREC-9 part of the OHSUMED collections, show that our feature selection algorithm produces models that are either significantly more effective than, or equally effective as, models such as Markov Random Field model, Correlation Co-efficient and Count Difference method

  12. Novel compound heterozygous DNA ligase IV mutations in an adolescent with a slowly-progressing radiosensitive-severe combined immunodeficiency.

    Science.gov (United States)

    Tamura, Shinobu; Higuchi, Kohei; Tamaki, Masaharu; Inoue, Chizuko; Awazawa, Ryoko; Mitsuki, Noriko; Nakazawa, Yuka; Mishima, Hiroyuki; Takahashi, Kenzo; Kondo, Osamu; Imai, Kohsuke; Morio, Tomohiro; Ohara, Osamu; Ogi, Tomoo; Furukawa, Fukumi; Inoue, Masami; Yoshiura, Koh-ichiro; Kanazawa, Nobuo

    2015-10-01

    We herein describe a case of a 17-year-old boy with intractable common warts, short stature, microcephaly and slowly-progressing pancytopenia. Simultaneous quantification of T-cell receptor recombination excision circles (TREC) and immunoglobulin κ-deleting recombination excision circles (KREC) suggested very poor generation of both T-cells and B-cells. By whole exome sequencing, novel compound heterozygous mutations were identified in the patient's DNA ligase IV (LIG4) gene. The diagnosis of LIG4 syndrome was confirmed by delayed DNA double-strand break repair kinetics in γ-irradiated fibroblasts from the patient and their restoration by an introduction of wild-type LIG4. Although the patient received allogeneic hematopoietic stem cell transplantation from his haploidentical mother, he unfortunately expired due to an insufficiently reconstructed immune system. An earlier definitive diagnosis using TREC/KREC quantification and whole exome sequencing would thereby allow earlier intervention, which would be essential for improving long-term survival in similar cases with slowly-progressing LIG4 syndrome masked in adolescents. Copyright © 2015 Elsevier Inc. All rights reserved.

  13. Long-lasting production of new T and B cells and T-cell repertoire diversity in patients with primary immunodeficiency who had undergone stem cell transplantation: a single-centre experience.

    Science.gov (United States)

    Valotti, Monica; Sottini, Alessandra; Lanfranchi, Arnalda; Bolda, Federica; Serana, Federico; Bertoli, Diego; Giustini, Viviana; Tessitore, Marion Vaglio; Caimi, Luigi; Imberti, Luisa

    2014-01-01

    Levels of Kappa-deleting recombination excision circles (KRECs), T-cell receptor excision circles (TRECs), and T-cell repertoire diversity were evaluated in 1038 samples of 124 children with primary immunodeficiency, of whom 102 (54 with severe combined immunodeficiency and 48 with other types of immunodeficiency) underwent hematopoietic stem cell transplantation. Twenty-two not transplanted patients with primary immunodeficiency were used as controls. Only data of patients from whom at least five samples were sent to the clinical laboratory for routine monitoring of lymphocyte reconstitutions were included in the analysis. The mean time of the follow-up was 8 years. The long-lasting posttransplantation kinetics of KREC and TREC production occurred similarly in patients with severe combined immunodeficiency and with other types of immunodeficiency and, in both groups, the T-cell reconstitution was more efficient than in nontransplanted children. Although thymic output decreased in older transplanted patients, the degree of T-cell repertoire diversity, after an initial increase, remained stable during the observation period. However, the presence of graft-versus-host disease and ablative conditioning seemed to play a role in the time-related shaping of T-cell repertoire. Overall, our data suggest that long-term B- and T-cell reconstitution was equally achieved in children with severe combined immunodeficiency and with other types of primary immunodeficiency.

  14. Quantification of newly produced B and T lymphocytes in untreated chronic lymphocytic leukemia patients

    Directory of Open Access Journals (Sweden)

    Caimi Luigi

    2010-11-01

    Full Text Available Abstract Background The immune defects occurring in chronic lymphocytic leukemia are responsible for the frequent occurrence of infections and autoimmune phenomena, and may be involved in the initiation and maintenance of the malignant clone. Here, we evaluated the quantitative defects of newly produced B and T lymphocytes. Methods The output of B and T lymphocytes from the production and maturation sites was analyzed in chronic lymphocytic leukemia patients and healthy controls by quantifying kappa-deleting recombination excision circles (KRECs and T-cell receptor excision circles (TRECs by a Real-Time PCR assay that simultaneously detects both targets. T-lymphocyte subsets were analyzed by six-color flow cytometric analysis. Data comparison was performed by two-sided Mann-Whitney test. Results KRECs level was reduced in untreated chronic lymphocytic leukemia patients studied at the very early stage of the disease, whereas the release of TRECs+ cells was preserved. Furthermore, the observed increase of CD4+ lymphocytes could be ascribed to the accumulation of CD4+ cells with effector memory phenotype. Conclusions The decreased number of newly produced B lymphocytes in these patients is likely related to a homeostatic mechanism by which the immune system balances the abnormal B-cell expansion. This feature may precede the profound defect of humoral immunity characterizing the later stages of the disease.

  15. ARCUS Internet Media Archive (IMA): A Resource for Outreach and Education

    Science.gov (United States)

    Polly, Z.; Warnick, W. K.; Polly, J.

    2008-12-01

    The ARCUS Internet Media Archive (IMA) is a collection of photos, graphics, videos, and presentations about the Arctic that are shared through the Internet. It provides the arctic research community and the public at large with a centralized location where images and video pertaining to polar research can be browsed and retrieved for a variety of uses. The IMA currently contains almost 6,500 publicly accessible photos, including 4,000 photos from the National Science Foundation funded Teachers and Researchers Exploring and Collaborating (TREC, now PolarTREC) program, an educational research experience in which K-12 teachers participate in arctic research as a pathway to improving science education. The IMA also includes 450 video files, 270 audio files, nearly 100 graphics and logos, 28 presentations, and approximately 10,000 additional resources that are being prepared for public access. The contents of this archive are organized by file type, contributor's name, event, or by organization, with each photo or file accompanied by information on content, contributor source, and usage requirements. All the files are key-worded and all information, including file name and description, is completely searchable. ARCUS plans to continue to improve and expand the IMA with a particular focus on providing graphics depicting key arctic research results and findings as well as edited video archives of relevant scientific community meetings. To submit files or for more information and to view the ARCUS Internet Media Archive, please go to: http://media.arcus.org or email photo@arcus.org.

  16. Clinical, Immunological, and Molecular Findings in Five Patients with Major Histocompatibility Complex Class II Deficiency from India

    Directory of Open Access Journals (Sweden)

    Jahnavi Aluri

    2018-02-01

    Full Text Available Major histocompatibility complex (MHC class II deficiency is a rare autosomal recessive form of primary immunodeficiency disorder (PID characterized by the deficiency of MHC class II molecules. This deficiency affects the cellular and humoral immune response by impairing the development of CD4+ T helper (Th cells and Th cell-dependent antibody production by B cells. Affected children typically present with severe respiratory and gastrointestinal tract infections. Hematopoietic stem cell transplantation (HSCT is the only curative therapy available for treating these patients. This is the first report from India wherein we describe the clinical, immunological, and molecular findings in five patients with MHC class II deficiency. Our patients presented with recurrent lower respiratory tract infection as the most common clinical presentation within their first year of life and had a complete absence of human leukocyte antigen-antigen D-related (HLA-DR expression on B cells and monocytes. Molecular characterization revealed novel mutations in RFAXP, RFX5, and CIITA genes. Despite genetic heterogeneity, these patients were clinically indistinguishable. Two patients underwent HSCT but had a poor survival outcome. Detectable level of T cell receptor excision circles (TRECs were measured in our patients, highlighting that this form of PID may be missed by TREC-based newborn screening program for severe combined immunodeficiency.

  17. Newborn Screening for Primary Immunodeficiency Diseases: The Past, the Present and the Future

    Directory of Open Access Journals (Sweden)

    Jovanka King

    2017-08-01

    Full Text Available Primary immunodeficiency diseases (PID are a heterogeneous group of disorders caused by inborn errors of immunity, with affected children presenting with severe, recurrent or unusual infections. Over 300 distinct genetic molecular abnormalities resulting in PID have been identified, and this number continues to rise. Newborn screening for PID has been established in many countries, with the majority of centers using a PCR-based T cell receptor excision circle (TREC assay to screen for severe combined immunodeficiency (SCID and other forms of T cell lymphopenia. Multiplexed screening including quantitation of kappa-recombining exclusion circles (KREC has also been described, offering advantages over TREC screening alone. Screening technologies are also expanding to include protein-based assays to identify complement deficiencies and granulocyte disorders. Given the rapid advances in genomic medicine, a potential future direction is the application of next-generation sequencing (NGS technologies to screen infants for a panel of genetic mutations, which would enable identification of a wide range of diseases. However, several ethical and economic issues must be considered before moving towards this screening strategy.

  18. Wow, My Science Teacher Does Real Research! Engaging and Motivating Students Using Experiences from the Field

    Science.gov (United States)

    Scott, C.

    2013-12-01

    Students respond to personal connections. When K-12 science teachers are able to participate as field assistants on research projects, their students can benefit greatly from the stories, pictures, and video transmitted or brought back from the field. Teachers can translate and tailor their learning while in the field to the level of their students. Students are ';hooked' into science content by seeing their own teacher out there actually ';doing' science. The teacher is able to provide a direct content connection for the student, an avenue for understanding why ';learning this' is relevant and important. This presentation provides a case for why science teachers and researchers should collaborate as much as possible. The NSF funded PolarTREC program (Teachers and Researchers Exploring and Collaborating) is an excellent example of how to make this collaboration work. The presentation will also provide a look into how teachers can make an effective connection for their students between field science and classroom learning. Alaskan secondary science teacher Carol Scott spent a month at the Kevo Research Station in northern Finland in May/June 2013 as a PolarTREC teacher, and is translating this experience for students. She has also worked on an NSF Research Experience for Teachers grant in Prince William Sound, AK, and has successfully used this work to engage students in the classroom.

  19. Ex vivo γ-retroviral gene therapy of dogs with X-linked severe combined immunodeficiency and the development of a thymic T cell lymphoma.

    Science.gov (United States)

    Kennedy, Douglas R; Hartnett, Brian J; Kennedy, Jeffrey S; Vernau, William; Moore, Peter F; O'Malley, Thomas; Burkly, Linda C; Henthorn, Paula S; Felsburg, Peter J

    2011-07-15

    We have previously shown that in vivo γ-retroviral gene therapy of dogs with X-linked severe combined immunodeficiency (XSCID) results in sustained T cell reconstitution and sustained marking in myeloid and B cells for up to 4 years with no evidence of any serious adverse effects. The purpose of this study was to determine whether ex vivo γ-retroviral gene therapy of XSCID dogs results in a similar outcome. Eight of 12 XSCID dogs treated with an average of dose of 5.8 × 10(6) transduced CD34(+) cells/kg successfully engrafted producing normal numbers of gene-corrected CD45RA(+) (naïve) T cells. However, this was followed by a steady decrease in CD45RA(+) T cells, T cell diversity, and thymic output as measured by T cell receptor excision circles (TRECs) resulting in a T cell lymphopenia. None of the dogs survived past 11 months post treatment. At necropsy, few gene-corrected thymocytes were observed correlating with the TREC levels and one of the dogs was diagnosed with a thymic T cell lymphoma that was attributed to the gene therapy. This study highlights the outcome differences between the ex vivo and in vivo approach to γ-retroviral gene therapy and is the first to document a serious adverse event following gene therapy in a canine model of a human genetic disease. Copyright © 2011 Elsevier B.V. All rights reserved.

  20. Effects of forearm vs. leg submersion in work tolerance time in a hot environment while wearing firefighter protective clothing.

    Science.gov (United States)

    Katica, Charles P; Pritchett, Robert C; Pritchett, Kelly L; Del Pozzi, Andrew T; Balilionis, Gytis; Burnham, Tim

    2011-08-01

    This study compared physiological responses and total work tolerance time following forearm submersion (FS) or leg submersion (LS) in cool water, after performing work in a hot environment while wearing fire fighting protective clothing (FPC). Participants walked at 3.5 mph on a treadmill in a hot environment (WBGT 32.8 ± 0.9°C) until a rectal temperature (T(rec)) of 38.5°C was reached. Participants were then subjected to one of two peripheral cooling interventions, in a counterbalanced order. Forearms or lower legs were submerged in water (16.9 ± 0.8°C) for a total of 20 min, followed by a work tolerance trial. Results indicated no significant difference (p = 0.052) between work tolerance time (LS = 21.36 ± 5.35 min vs. FS = 16.27 ± 5.56 min). Similarly, there was no significant difference for T(rec) (p = 0.65), heart rate (HR) (p = 0.79), mean skin temperature (T(sk)) (p = 0.68), and rating of perceived exertion (RPE) (p = 0.54). However, LS ratings of thermal comfort (RTC) at Minute 14 (p = 0.03) were significantly lower for LS (10 ± 1) vs. FS (12 ± 1). Results indicate little difference between FS and LS for physiological measures. Despite a lack of statistical significance a 5-min (24%) increase was found during the work tolerance time following LS.

  1. Utilizing Multi-Field Text Features for Efficient Email Spam Filtering

    Directory of Open Access Journals (Sweden)

    Wuying Liu

    2012-06-01

    Full Text Available Large-scale spam emails cause a serious waste of time and resources. This paper investigates the text features of email documents and the feature noises among multi-field texts, resulting in an observation of a power law distribution of feature strings within each text field. According to the observation, we propose an efficient filtering approach including a compound weight method and a lightweight field text classification algorithm. The compound weight method considers both the historical classifying ability of each field classifier and the classifying contribution of each text field in the current classified email. The lightweight field text classification algorithm straightforwardly calculates the arithmetical average of multiple conditional probabilities predicted from feature strings according to a string-frequency index for labeled emails storing. The string-frequency index structure has a random-sampling-based compressible property owing to the power law distribution and can largely reduce the storage space. The experimental results in the TREC spam track show that the proposed approach can complete the filtering task in low space cost and high speed, whose overall performance 1-ROCA exceeds the best one among the participators at the trec07p evaluation.

  2. NASA Operation IceBridge Flies Into the Classroom!

    Science.gov (United States)

    Kane, M.

    2017-12-01

    Field research opportunities for educators is leveraged as an invaluable tool to increase public engagement in climate research and the geosciences. We investigate the influence of educator's authentic fieldwork by highlighting the post-field impacts of a PolarTREC Teacher who participated in two campaigns, including NASA Operation IceBridge campaign over Antarctica in 2016. NASA's Operation IceBridge has hosted PolarTREC teachers since 2012, welcoming five teachers aboard multiple flights over the Arctic and one over Antarctica. The continuity of teacher inclusion in Operation IceBridge campaigns has facilitated a platform for collaborative curriculum development and revision, integration of National Snow and Ice Data Center (NSIDC) data into multiple classrooms, and given us a means whereby students can interact with science team members. I present impacts to my teaching and classrooms as I grapple with "Big Data" to allow students to work directly with lidar and radar data, I examine public outreach impacts through analytics from virtual networking tools including social media, NASA's Mission Tools Suite for Education, and field blog interactions.

  3. Characterizing T Cells in SCID Patients Presenting with Reactive or Residual T Lymphocytes

    Directory of Open Access Journals (Sweden)

    Atar Lev

    2012-01-01

    Full Text Available Introduction. Patients with severe combined immunodeficiency (SCID may present with residual circulating T cells. While all cells are functionally deficient, resulting in high susceptibility to infections, only some of these cells are causing autoimmune symptoms. Methods. Here we compared T-cell functions including the number of circulating CD3+ T cells, in vitro responses to mitogens, T-cell receptor (TCR repertoire, TCR excision circles (TREC levels, and regulatory T cells (Tregs enumeration in several immunodeficinecy subtypes, clinically presenting with nonreactive residual cells (MHC-II deficiency or reactive cells. The latter includes patients with autoreactive clonal expanded T cell and patients with alloreactive transplacentally maternal T cells. Results. MHC-II deficient patients had slightly reduced T-cell function, normal TRECs, TCR repertoires, and normal Tregs enumeration. In contrast, patients with reactive T cells exhibited poor T-cell differentiation and activity. While the autoreactive cells displayed significantly reduced Tregs numbers, the alloreactive transplacentally acquired maternal lymphocytes had high functional Tregs. Conclusion. SCID patients presenting with circulating T cells show different patterns of T-cell activity and regulatory T cells enumeration that dictates the immunodeficient and autoimmune manifestations. We suggest that a high-tolerance capacity of the alloreactive transplacentally acquired maternal lymphocytes represents a toleration advantage, yet still associated with severe immunodeficiency.

  4. Long-Lasting Production of New T and B Cells and T-Cell Repertoire Diversity in Patients with Primary Immunodeficiency Who Had Undergone Stem Cell Transplantation: A Single-Centre Experience

    Directory of Open Access Journals (Sweden)

    Monica Valotti

    2014-01-01

    Full Text Available Levels of Kappa-deleting recombination excision circles (KRECs, T-cell receptor excision circles (TRECs, and T-cell repertoire diversity were evaluated in 1038 samples of 124 children with primary immunodeficiency, of whom 102 (54 with severe combined immunodeficiency and 48 with other types of immunodeficiency underwent hematopoietic stem cell transplantation. Twenty-two not transplanted patients with primary immunodeficiency were used as controls. Only data of patients from whom at least five samples were sent to the clinical laboratory for routine monitoring of lymphocyte reconstitutions were included in the analysis. The mean time of the follow-up was 8 years. The long-lasting posttransplantation kinetics of KREC and TREC production occurred similarly in patients with severe combined immunodeficiency and with other types of immunodeficiency and, in both groups, the T-cell reconstitution was more efficient than in nontransplanted children. Although thymic output decreased in older transplanted patients, the degree of T-cell repertoire diversity, after an initial increase, remained stable during the observation period. However, the presence of graft-versus-host disease and ablative conditioning seemed to play a role in the time-related shaping of T-cell repertoire. Overall, our data suggest that long-term B- and T-cell reconstitution was equally achieved in children with severe combined immunodeficiency and with other types of primary immunodeficiency.

  5. Common Variable Immunodeficiency Caused by FANC Mutations.

    Science.gov (United States)

    Sekinaka, Yujin; Mitsuiki, Noriko; Imai, Kohsuke; Yabe, Miharu; Yabe, Hiromasa; Mitsui-Sekinaka, Kanako; Honma, Kenichi; Takagi, Masatoshi; Arai, Ayako; Yoshida, Kenichi; Okuno, Yusuke; Shiraishi, Yuichi; Chiba, Kenichi; Tanaka, Hiroko; Miyano, Satoru; Muramatsu, Hideki; Kojima, Seiji; Hira, Asuka; Takata, Minoru; Ohara, Osamu; Ogawa, Seishi; Morio, Tomohiro; Nonoyama, Shigeaki

    2017-07-01

    Common variable immunodeficiency (CVID) is the most common adult-onset primary antibody deficiency disease due to various causative genes. Several genes, which are known to be the cause of different diseases, have recently been reported as the cause of CVID in patients by performing whole exome sequencing (WES) analysis. Here, we found FANC gene mutations as a cause of adult-onset CVID in two patients. B cells were absent and CD4 + T cells were skewed toward CD45RO + memory T cells. T-cell receptor excision circles (TRECs) and signal joint kappa-deleting recombination excision circles (sjKRECs) were undetectable in both patients. Both patients had no anemia, neutropenia, or thrombocytopenia. Using WES, we identified compound heterozygous mutations of FANCE in one patient and homozygous mutation of FANCA in another patient. The impaired function of FANC protein complex was confirmed by a monoubiquitination assay and by chromosome fragility test. We then performed several immunological evaluations including quantitative lymphocyte analysis and TRECs/sjKRECs analysis for 32 individuals with Fanconi anemia (FA). In total, 22 FA patients (68.8%) were found to have immunological abnormalities, suggesting that such immunological findings may be common in FA patients. These data indicate that FANC mutations are involved in impaired lymphogenesis probably by the accumulation of DNA replication stress, leading to CVID. It is important to diagnose FA because it drastically changes clinical management. We propose that FANC mutations can cause isolated immunodeficiency in addition to bone marrow failure and malignancy.

  6. Uremia causes premature ageing of the T cell compartment in end-stage renal disease patients

    Directory of Open Access Journals (Sweden)

    Meijers Ruud WJ

    2012-09-01

    Full Text Available Abstract Background End-stage renal disease (ESRD patients treated with renal replacement therapy (RRT have premature immunologically aged T cells which may underlie uremia-associated immune dysfunction. The aim of this study was to investigate whether uremia was able to induce premature ageing of the T cell compartment. For this purpose, we examined the degree of premature immunological T cell ageing by examining the T cell differentiation status, thymic output via T cell receptor excision circle (TREC content and proliferative history via relative telomere length in ESRD patients not on RRT. Results Compared to healthy controls, these patients already had a lower TREC content and an increased T cell differentiation accompanied by shorter telomeres. RRT was able to enhance CD8+ T cell differentiation and to reduce CD8+ T cell telomere length in young dialysis patients. An increased differentiation status of memory CD4+ T cells was also noted in young dialysis patients. Conclusion Based on these results we can conclude that uremia already causes premature immunological ageing of the T cell system and RRT further increases immunological ageing of the CD8+ T cell compartment in particular in young ESRD patients.

  7. Arctic Collaboration: Developing a Successful Researcher/Teacher Expedition

    Science.gov (United States)

    Skotnicki, S.; Loranty, M. M.

    2016-12-01

    Are you a researcher working in the polar regions of the world or a K-12 science teacher who would like to be part of a field research expedition in the polar regions? Researchers and K-12 science teachers can apply for funding from PolarTREC, a program that pairs researchers and teachers to conduct field science in Antarctica and the Arctic. Our poster presentation will offer details of one such successful researcher/teacher partnership. During the summer of 2016, Science Teacher Stan Skotnicki (Cheektowaga Central Middle School in Buffalo, NY) was teamed up with Assistant Professor Mike Loranty (Colgate University) to study vegetation and ecosystem impacts on permafrost vulnerability. Stan joined Mike and his research team in Northeastern Siberia preparing field sites, collecting data, processing samples, discussing methods, and planning daily activities. In order to raise awareness and broaden the impact of the research being conducted, Stan communicated the science through a series of journals on the PolarTREC website with his students, staff, and members of the community. Additionally, Mike and Stan held a live webinar from Siberia discussing the content of the research, the nature of the fieldwork, and why it was important to travel so far for this information. This expedition allowed Stan to experience working with a field research team for an extended period of time. Mike benefited from having a team member dedicated to learning about and communicating project details that also provided valuable field assistance. Stan gets to bring his hands-on experience back to his classroom in Buffalo and Mike has the opportunity to share his research with a new and different audience, including presenting to students at Cheektowaga Central with the help of his undergraduate students. This model of collaboration provides a number of valuable benefits for both teachers and researchers. While the PolarTREC program provides necessary logistics and funding to conduct these

  8. The structure and function of cell membranes studied by atomic force microscopy.

    Science.gov (United States)

    Shi, Yan; Cai, Mingjun; Zhou, Lulu; Wang, Hongda

    2018-01-01

    The cell membrane, involved in almost all communications of cells and surrounding matrix, is one of the most complicated components of cells. Lack of suitable methods for the detection of cell membranes in vivo has sparked debates on the biochemical composition and structure of cell membranes over half a century. The development of single molecule techniques, such as AFM, SMFS, and TREC, provides a versatile platform for imaging and manipulating cell membranes in biological relevant environments. Here, we discuss the latest developments in AFM and the progress made in cell membrane research. In particular, we highlight novel structure models and dynamic processes, including the mechanical properties of the cell membranes. Copyright © 2017 Elsevier Ltd. All rights reserved.

  9. Data fusion according to the principle of polyrepresentation

    DEFF Research Database (Denmark)

    Larsen, Birger; Ingwersen, Peter; Lund, Berit

    2009-01-01

    We report data fusion experiments carried out on the four best-performing retrieval models from TREC 5. Three were conceptually/algorithmically very different from one another; one was algorithmically similar to one of the former. The objective of the test was to observe the performance of the 11...... as a representation of a unique interpretation of information retrieval (IR). It predicts that only fusions of very different, but equally good, IR models may outperform each constituent as well as their intermediate fusions. Two kinds of experiments were carried out. One tested restricted fusions, which entails...... used. Performance was measured by precision and recall, with document cutoff values (DCVs) at 100 and 15 documents, respectively. Results show that restricted fusions made of two, three, or four cognitively/algorithmically very different retrieval models perform significantly better than do...

  10. Cluster-based query expansion using external collections in medical information retrieval.

    Science.gov (United States)

    Oh, Heung-Seon; Jung, Yuchul

    2015-12-01

    Utilizing external collections to improve retrieval performance is challenging research because various test collections are created for different purposes. Improving medical information retrieval has also gained much attention as various types of medical documents have become available to researchers ever since they started storing them in machine processable formats. In this paper, we propose an effective method of utilizing external collections based on the pseudo relevance feedback approach. Our method incorporates the structure of external collections in estimating individual components in the final feedback model. Extensive experiments on three medical collections (TREC CDS, CLEF eHealth, and OHSUMED) were performed, and the results were compared with a representative expansion approach utilizing the external collections to show the superiority of our method. Copyright © 2015 Elsevier Inc. All rights reserved.

  11. Undercooling and nodule count in thin walled ductile iron castings

    DEFF Research Database (Denmark)

    Pedersen, Karl Martin; Tiedje, Niels Skat

    2007-01-01

    Casting experiments have been performed with eutectic and hypereutectic castings with plate thick¬nesses from 2 to 8 mm involving both temperature measurements during solidification and micro¬structural examination afterwards. The nodule count was the same for the eutectic and hypereutectic...... castings in the thin plates ( 4.3 mm) while in the 8 mm plate the nodule count was higher in the hypereutectic than in the eutectic castings. The minimum temperature prior to the eutectic recalescence (Tmin) was 15 to 20C lower for the eutectic than the hypereutectic castings. This is due to nucleation...... of graphite nodules which begins at a lover temperature in the eutectic than in the hypereutectic castings The recalescence (Trec) was however also larger for the eutectic casting and in the thin plates the maximum temperature after recalescence (Tmax) was the same in the eutectic and hypereutectic plates...

  12. Undercooling and nodule count in thin walled ductile iron castings

    DEFF Research Database (Denmark)

    Pedersen, Karl Martin; Tiedje, Niels Skat

    2007-01-01

    Casting experiments have been performed with eutectic and hypereutectic castings with plate thicknesses from 2 to 8 mm involving both temperature measurements during solidification and microstructural examination afterwards. The nodule count was the same for the eutectic and hypereutectic castings...... in the thin plates (≤4.3 mm) while in the 8 mm plate the nodule count was higher in the hypereutectic than in the eutectic castings. The minimum temperature before the eutectic recalescence (Tmin) was 15 to 20ºC lower for the eutectic than for the hypereutectic castings. This is due to nucleation of graphite...... nodules which begins at a lower temperature in the eutectic than in the hypereutectic castings. The recalescence ∆Trec was however also larger for the eutectic casting and in the thin plates the maximum temperature after recalescence (Tmax) was the same in the eutectic and hypereutectic plates...

  13. The AMTEX Partnership. Third quarter report

    Energy Technology Data Exchange (ETDEWEB)

    1994-06-01

    The AMTEX Partnership is a collaborative research and development program among the U.S. Integrated Textile Industry, the Department of Energy, The DOE laboratories, other federal agencies and laboratories, and universities. The goal of AMTEX is to strengthen the competitiveness of this vital U.S. industry and thereby preserve and create American jobs. During the third quarter of 1994 all the Cooperative Research and Development Agreements (CRADAs) were completed and work initiated for three additional projects: Computer Aided Fabric Evaluation (CAFE), Textile Resource Conservation (TReC), and Sensors for Agile Manufacturing (SFAM). The plan for a Cotton Biotechnology project was completed and reviewed by the Industry Technical Advisory Committee. In addition, an `impact study` on the topic of flexible fiber production was conducted by an industry group led by the fiber manufacturers.

  14. EFFECTS OF PALM VITAMIN E SUPPLEMENTATION ON EXERCISE-INDUCED OXIDATIVE STRESS AND ENDURANCE PERFORMANCE IN THE HEAT

    Directory of Open Access Journals (Sweden)

    Chen Chee Keong

    2006-12-01

    Full Text Available This study investigates the effects of tocotrienol-rich palm vitamin E supplementation on exercise-induced lipid peroxidation and endurance performance in the heat. In a double blind, cross-over study, eighteen healthy, male recreational athletes completed two endurance running trials, until exhaustion, on a motorized treadmill at 70% VO2max on two separate occasions following a 6-week supplementation regimen of either tocotrienol-rich palm vitamin E (E or placebo (P. Both trials were conducted in the heat (31oC, 70% relative humidity. During the trials, rectal temperature (Trec, ratings of perceived exertion (RPE and oxygen uptake (VO2 were recorded. Blood samples were collected for the determination of plasma volume changes (PVC, malondialdehyde (MDA, creatine kinase (CK, total antioxidant status (TAS and vitamin E. After the supplementation regimen, serum alpha-tocopherol increased ~33% but serum concentrations of tocotrienols were negligible. No significant differences were evident in mean Trec, RPE, VO2 or in the time to exhaustion between the E-supplemented and the placebo- supplemented groups. Similarly, mean PVC, CK and TAS were also not different between the two groups. Resting plasma mean MDA concentration in the E-supplemented group was significantly lower than that in the placebo-supplemented group. At exhaustion, plasma mean MDA was higher than the resting values in both groups. Although tocotrienol-rich palm vitamin E supplementation decreased lipid peroxidation at rest and, to some extent, during exercise in the heat, as evident from the lower MDA levels, it however did not enhance endurance running performance or prevent exercise-induced muscle damage or influenced body core temperature or plasma volume changes during exercise in the heat

  15. The Benefits of Being a Student of Teacher Researchers Experiences (sotre)

    Science.gov (United States)

    Eubanks, E.; Guinan, E.; Chiste, M.; Lavoie, A.

    2016-02-01

    Being a Student of Teacher Researcher Experiences (SoTRE), gets students excited for science. Eubanks brings real, current science to the classroom because of time spent in Teacher Researcher Experiences (TRE), where she works with researchers in and out of the field. She involves students in many programs including the National Oceanographic and Atmospheric Administration (NOAA), Polar TREC (Teachers and Researchers & Exploring & Collaboration), National Science Foundation (NSF) funded researchers, (EARTH) Education and Research: Testing Hypothesis, the RJ Dunlap Marine Conservation Program, C-DEBI (Center for Dark Energy Biosphere Investigations and (STARS) Sending Teachers Aboard Research Ships. Being in these programs gives students special privileges such as understanding unique research ideas, tracking tagged sharks, following daily journals written on location, taking part in cross-continental experiments, tracking real time data, exploring current research via posters or visiting universities. Furthermore, contacts made by a TRE give students an added set of resources. When doing experiments for class or advancing their education or career goals, Mrs. Eubanks helps students connect with scientists. This gives students a unique opportunity to learn from real scientists. Being part of these relationships with NOAA, Polar TREC, EARTH, RJ Dunlap, STARS and NSF funded scientists who are actively working, makes being SoTRE the ultimate learning experience. Many students have felt so strongly about the TRE relationship that they have presented at several local and international science conferences. Their message is to encourage scientists to partner with teachers. The benefits of participation in such conferences have included abstract writing and submission, travel, poster creation, networking and presentation, all tools that they will carry with them for a lifetime.

  16. Field-enhanced route to generating anti-Frenkel pairs in HfO2

    Science.gov (United States)

    Schie, Marcel; Menzel, Stephan; Robertson, John; Waser, Rainer; De Souza, Roger A.

    2018-03-01

    The generation of anti-Frenkel pairs (oxygen vacancies and oxygen interstitials) in monoclinic and cubic HfO2 under an applied electric field is examined. A thermodynamic model is used to derive an expression for the critical field strength required to generate an anti-Frenkel pair. The critical field strength of EaFcr˜101GVm-1 obtained for HfO2 exceeds substantially the field strengths routinely employed in the forming and switching operations of resistive switching HfO2 devices, suggesting that field-enhanced defect generation is negligible. Atomistic simulations with molecular static (MS) and molecular dynamic (MD) approaches support this finding. The MS calculations indicated a high formation energy of Δ EaF≈8 eV for the infinitely separated anti-Frenkel pair, and only a decrease to Δ EaF≈6 eV for the adjacent anti-Frenkel pair. The MD simulations showed no defect generation in either phase for E <3 GVm-1 , and only sporadic defect generation in the monoclinic phase (at E =3 GVm-1 ) with fast (trec<4 ps ) recombination. At even higher E but below EaFcr both monoclinic and cubic structures became unstable as a result of field-induced deformation of the ionic potential wells. Further MD investigations starting with preexisting anti-Frenkel pairs revealed recombination of all pairs within trec<1 ps , even for the case of neutral vacancies and charged interstitials, for which formally there is no electrostatic attraction between the defects. In conclusion, we find no physically reasonable route to generating point-defects in HfO2 by an applied field.

  17. Immersion with menthol improves recovery between two cycling exercises in hot and humid environment.

    Science.gov (United States)

    Rinaldi, Kévin; Tran Trong, Than; Riera, Florence; Appel, Katharina; Hue, Olivier

    2018-03-13

    Endurance exercise performance is impaired in a hot and humid environment. This study compared the effects of cold water immersion, with (CMWI) and without (CWI) menthol, on the recovery of cycling performance. Eight heat-acclimatized cyclists (24.1 ± 4.4 years; 65.3 ± 5.2 kg) performed two randomized sessions, each consisting of a 20-min cycling trial (T1) followed by 10 min of immersion during recovery and then a second 20-min cycling trial (T2). Mean power output (PO) and perceived exertion (RPE) were recorded for both trials. Rectal and skin temperatures (Trec and Tskin) were measured before and immediately after T1, immersion, and T2. Perceived thermal sensation (TS) and comfort (TC) were measured immediately after T1 and T2. Power output was significantly improved in T2 compared with T1 in the CMWI condition (+15.6%). Performance did not change in the CWI condition. After immersion, Trec was lower in CWI (-1.17°C) than in CMWI (-0.6°C). TS decreased significantly after immersion in both conditions. This decline was significantly more pronounced in CMWI (5.9 ± 1 to 3.6 ± 0.5) than in CWI (5.6 ± 0.9 to 4.4 ± 1.2). In CMWI, RPE was significantly higher in T1 (6.57 ± 0.9) than in T2 (5.14 ± 1.25). However there was no difference in TC. This study suggests that menthol immersion probably (1) improves the performance of a repeated 20-min cycling bout, (2) decreases TS, and (3) impairs thermoregulation processes.

  18. Chapter 27: Approach to primary immunodeficiency.

    Science.gov (United States)

    Uzzaman, Ashraf; Fuleihan, Ramsay L

    2012-01-01

    Primary immunodeficiency diseases (PID) are inherited defects of the innate or adaptive arms of the immune system that lead to an increase in the incidence, frequency, or severity of infections. There may be defects in the adaptive arm of the immune system that include combined immunodeficiency and antibody deficiency syndromes or by abnormalities in innate immunity such as disorders of phagocytes, the complement pathway, or Toll-Like receptor (TLR) mediated signaling. Recurrent sinopulmonary infections with encapsulated bacteria such as Haemophilus influenza type B or Streptococcus pneumoniae may be characteristic of an IgG antibody deficiency or dysfunction. Frequent viral, fungal, or protozoal infections may suggest T lymphocyte dysfunction. Multiple staphylococcal skin infections and fungal infections may imply neutrophil dysfunction or the hyper-IgE syndrome, and recurrent neisserial infection is a characteristic manifestation of late complement component (C5-9, or the membrane attack complex) defects. Recurrent viral or pyogenic bacterial infections often without the presence of a significant inflammatory response suggest a defect in TLR signaling. Mycobacterial infections are characteristic of defects in interleukin (IL)-12, interferon (IFN) gamma, or their receptors. Screening of newborns for T-cell lymphopenia using a polymerase chain reaction to amplify T-cell receptor excision circles (TRECs), which are formed when a T cell rearranges the variable region of its receptor, serves as a surrogate for newly synthesized naïve T cells. Because of very low numbers of TRECs, severe combined immunodeficiency, DiGeorge syndrome, and other causes of T-cell lymphopenia have been identified in newborns.

  19. Progressive Activation of CD127+132− Recent Thymic Emigrants into Terminally Differentiated CD127−132+ T-Cells in HIV-1 Infection

    Science.gov (United States)

    Sasson, Sarah C.; Zaunders, John J.; Seddiki, Nabila; Bailey, Michelle; McBride, Kristin; Koelsch, Kersten K.; Merlin, Kate M.; Smith, Don E.; Cooper, David A.; Kelleher, Anthony D.

    2012-01-01

    Aim HIV infection is associated with distortion of T-cell homeostasis and the IL-7/IL7R axis. Progressive infection results in loss of CD127+132− and gains in CD127−132+ CD4+ and CD8+ T-cells. We investigated the correlates of loss of CD127 from the T-cell surface to understand mechanisms underlying this homeostatic dysregulation. Methods Peripheral and cord blood mononuclear cells (PBMCs; CBMC) from healthy volunteers and PBMC from patients with HIV infection were studied. CD127+132−, CD127+132+ and CD127−132+ T-cells were phenotyped by activation, differentiation, proliferation and survival markers. Cellular HIV-DNA content and signal-joint T-cell receptor excision circles (sjTRECs) were measured. Results CD127+132− T-cells were enriched for naïve cells while CD127−132+ T-cells were enriched for activated/terminally differentiated T-cells in CD4+ and CD8+ subsets in health and HIV infection. HIV was associated with increased proportions of activated/terminally differentiated CD127−132+ T-cells. In contrast to CD127+132− T-cells, CD127−132+ T-cells were Ki-67+Bcl-2low and contained increased levels of HIV-DNA. Naïve CD127+132− T-cells contained a higher proportion of sjTRECs. Conclusion The loss of CD127 from the T-cell surface in HIV infection is driven by activation of CD127+132− recent thymic emigrants into CD127−132+ activated/terminally differentiated cells. This process likely results in an irreversible loss of CD127 and permanent distortion of T-cell homeostasis. PMID:22348045

  20. Progressive activation of CD127+132- recent thymic emigrants into terminally differentiated CD127-132+ T-cells in HIV-1 infection.

    Directory of Open Access Journals (Sweden)

    Sarah C Sasson

    Full Text Available AIM: HIV infection is associated with distortion of T-cell homeostasis and the IL-7/IL7R axis. Progressive infection results in loss of CD127+132- and gains in CD127-132+ CD4+ and CD8+ T-cells. We investigated the correlates of loss of CD127 from the T-cell surface to understand mechanisms underlying this homeostatic dysregulation. METHODS: Peripheral and cord blood mononuclear cells (PBMCs; CBMC from healthy volunteers and PBMC from patients with HIV infection were studied. CD127+132-, CD127+132+ and CD127-132+ T-cells were phenotyped by activation, differentiation, proliferation and survival markers. Cellular HIV-DNA content and signal-joint T-cell receptor excision circles (sjTRECs were measured. RESULTS: CD127+132- T-cells were enriched for naïve cells while CD127-132+ T-cells were enriched for activated/terminally differentiated T-cells in CD4+ and CD8+ subsets in health and HIV infection. HIV was associated with increased proportions of activated/terminally differentiated CD127-132+ T-cells. In contrast to CD127+132- T-cells, CD127-132+ T-cells were Ki-67+Bcl-2(low and contained increased levels of HIV-DNA. Naïve CD127+132- T-cells contained a higher proportion of sjTRECs. CONCLUSION: The loss of CD127 from the T-cell surface in HIV infection is driven by activation of CD127+132- recent thymic emigrants into CD127-132+ activated/terminally differentiated cells. This process likely results in an irreversible loss of CD127 and permanent distortion of T-cell homeostasis.

  1. Modeling and mining term association for improving biomedical information retrieval performance.

    Science.gov (United States)

    Hu, Qinmin; Huang, Jimmy Xiangji; Hu, Xiaohua

    2012-06-11

    The growth of the biomedical information requires most information retrieval systems to provide short and specific answers in response to complex user queries. Semantic information in the form of free text that is structured in a way makes it straightforward for humans to read but more difficult for computers to interpret automatically and search efficiently. One of the reasons is that most traditional information retrieval models assume terms are conditionally independent given a document/passage. Therefore, we are motivated to consider term associations within different contexts to help the models understand semantic information and use it for improving biomedical information retrieval performance. We propose a term association approach to discover term associations among the keywords from a query. The experiments are conducted on the TREC 2004-2007 Genomics data sets and the TREC 2004 HARD data set. The proposed approach is promising and achieves superiority over the baselines and the GSP results. The parameter settings and different indices are investigated that the sentence-based index produces the best results in terms of the document-level, the word-based index for the best results in terms of the passage-level and the paragraph-based index for the best results in terms of the passage2-level. Furthermore, the best term association results always come from the best baseline. The tuning number k in the proposed recursive re-ranking algorithm is discussed and locally optimized to be 10. First, modelling term association for improving biomedical information retrieval using factor analysis, is one of the major contributions in our work. Second, the experiments confirm that term association considering co-occurrence and dependency among the keywords can produce better results than the baselines treating the keywords independently. Third, the baselines are re-ranked according to the importance and reliance of latent factors behind term associations. These latent

  2. Vaccine-associated varicella and rubella infections in severe combined immunodeficiency with isolated CD4 lymphocytopenia and mutations in IL7R detected by tandem whole exome sequencing and chromosomal microarray

    Science.gov (United States)

    Bayer, D K; Martinez, C A; Sorte, H S; Forbes, L R; Demmler-Harrison, G J; Hanson, I C; Pearson, N M; Noroski, L M; Zaki, S R; Bellini, W J; Leduc, M S; Yang, Y; Eng, C M; Patel, A; Rodningen, O K; Muzny, D M; Gibbs, R A; Campbell, I M; Shaw, C A; Baker, M W; Zhang, V; Lupski, J R; Orange, J S; Seeborg, F O; Stray-Pedersen, A

    2014-01-01

    In areas without newborn screening for severe combined immunodeficiency (SCID), disease-defining infections may lead to diagnosis, and in some cases, may not be identified prior to the first year of life. We describe a female infant who presented with disseminated vaccine-acquired varicella (VZV) and vaccine-acquired rubella infections at 13 months of age. Immunological evaluations demonstrated neutropenia, isolated CD4 lymphocytopenia, the presence of CD8+ T cells, poor lymphocyte proliferation, hypergammaglobulinaemia and poor specific antibody production to VZV infection and routine immunizations. A combination of whole exome sequencing and custom-designed chromosomal microarray with exon coverage of primary immunodeficiency genes detected compound heterozygous mutations (one single nucleotide variant and one intragenic copy number variant involving one exon) within the IL7R gene. Mosaicism for wild-type allele (20–30%) was detected in pretransplant blood and buccal DNA and maternal engraftment (5–10%) demonstrated in pretransplant blood DNA. This may be responsible for the patient's unusual immunological phenotype compared to classical interleukin (IL)-7Rα deficiency. Disseminated VZV was controlled with anti-viral and immune-based therapy, and umbilical cord blood stem cell transplantation was successful. Retrospectively performed T cell receptor excision circle (TREC) analyses completed on neonatal Guthrie cards identified absent TREC. This case emphasizes the danger of live viral vaccination in severe combined immunodeficiency (SCID) patients and the importance of newborn screening to identify patients prior to high-risk exposures. It also illustrates the value of aggressive pathogen identification and treatment, the influence newborn screening can have on morbidity and mortality and the significant impact of newer genomic diagnostic tools in identifying the underlying genetic aetiology for SCID patients. PMID:25046553

  3. Stem cell mobilization in idiopathic steroid-sensitive nephrotic syndrome.

    Science.gov (United States)

    Lapillonne, Hélène; Leclerc, Annelaure; Ulinski, Tim; Balu, Laurent; Garnier, Arnaud; Dereuddre-Bosquet, Nathalie; Watier, Hervé; Schlageter, Marie-Hélène; Deschênes, Georges

    2008-08-01

    Steroid-sensitive nephrotic syndrome (SSNS) is classically thought to be a T-cell disorder. The aim of this study was to examine whether or not thymus homeostasis was affected in SSNS. Mature and naive T cell recent thymic emigrants were quantified in the peripheral blood of nephrotic patients and controls. Because the generation of new T cells by the thymus ultimately depends on hematopoietic stem cells, CD34+ cells were also included in the study. Nineteen patients with SSNS during relapse, 13 with SSNS during proteinuria remission, and 18 controls were studied. Cell-surface markers (CD3, CD4, CD8, CD19, CD16, CD56, CD45RA, CD62L, CD34, and CD38) were analyzed by flow cytometric analysis. T-cell rearrangement excision circles (TRECs) were quantified in CD2+ cells by real-time polymerase chain reaction. Stroma cell-derived factor-1 (SDF-1) genotype and metalloproteinase-9 (MMP-9) plasma levels were also determined. Mature T cells (CD4+ and CD8+), circulating naive T cells (CD62L+ and CD3+ CD62L+), and recent thymic emigrants (CD45RA+) as well as TRECs, that measure thymus production, had a similar level in the three groups of patients. Conversely, CD34+ hematopoietic stem cells displayed a two-fold increase in SSNS patients during relapse either compared with controls or SSNS patients at remission. In addition, compared with controls, SSNS patients at remission displayed (1) a decrease in CD19+ cells (B cells) and (2) an increase in CD16CD56+ cells [natural killer (NK) cells]. In conclusion, thymus homeostasis is not significantly affected in nephrotic patients. Hematopoietic stem-cell mobilization at proteinuria relapse, as well as changes in B and NK cells during remission, suggest that SSNS might be due to a general disturbance of hematopoietic and immune cell trafficking.

  4. Patients with T⁺/low NK⁺ IL-2 receptor γ chain deficiency have differentially-impaired cytokine signaling resulting in severe combined immunodeficiency.

    Science.gov (United States)

    Fuchs, Sebastian; Rensing-Ehl, Anne; Erlacher, Miriam; Vraetz, Thomas; Hartjes, Lara; Janda, Ales; Rizzi, Marta; Lorenz, Myriam R; Gilmour, Kimberly; de Saint-Basile, Geneviève; Roifman, Chaim M; Cheuk, Steven; Gennery, Andrew; Thrasher, Adrian J; Fuchs, Ilka; Schwarz, Klaus; Speckmann, Carsten; Ehl, Stephan

    2014-10-01

    X-linked severe combined immunodeficiency (X-SCID) leads to a T(-) NK(-) B(+) immunophenotype and is caused by mutations in the gene encoding the IL-2 receptor γ-chain (IL2RG). IL2RG(R222C) leads to atypical SCID with a severe early onset phenotype despite largely normal NK- and T-cell numbers. To address this discrepancy, we performed a detailed analysis of T, B, and NK cells, including quantitative STAT phosphorylation and functional responses to the cytokines IL-2, IL-4, IL-15, and IL-21 in a patient with the IL2RG(R222C) mutation. Moreover, we identified nine additional unpublished patients with the same mutations, all with a full SCID phenotype, and confirmed selected immunological observations. T-cell development was variably affected, but led to borderline T-cell receptor excision circle (TREC) levels and a normal repertoire. T cells showed moderately reduced proliferation, failing enhancement by IL-2. While NK-cell development was normal, IL-2 enhancement of NK-cell degranulation and IL-15-induced cytokine production were absent. IL-2 or IL-21 failed to enhance B-cell proliferation and plasmablast differentiation. These functional alterations were reflected by a differential impact of IL2RG(R222C) on cytokine signal transduction, with a gradient IL-4severe clinical phenotype that is not predicted by the variable and moderate impairment of T-cell immunity or TREC analysis. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  5. A MID-INFRARED VIEW OF THE HIGH MASS STAR FORMATION REGION W51A

    Energy Technology Data Exchange (ETDEWEB)

    Barbosa, C. L. [Laboratório Nacional de Astrofísica, R. dos Estados Unidos, Bairro das Nações, CEP 37504-364, Itajubá—MG (Brazil); Blum, R. D. [National Optical Astronomy Observatory, Tucson, AZ 85719 (United States); Damineli, A. [Instituto de Astronomia, Geofísica e Ciências Atmosféricas, Universidade de São Paulo, R. do Matão, 1226, Cid. Universitária, São Paulo 05508-900 (Brazil); Conti, P. S. [JILA, University of Colorado, Boulder, CO 80309-0440 (United States); Gusmão, D. M., E-mail: cassio.barbosa@pq.cnpq.br, E-mail: rblum@noao.edu, E-mail: augusto.damineli@iag.usp.br, E-mail: pconti@jila.colorado.edu, E-mail: danilo@univap.br [IP and D—Universidade do Vale do Paraíba, Av. Shishima Hifumi, 2911. São José dos Campos, SP, 12244-000 (Brazil)

    2016-07-01

    In this paper we present the results of a mid-infrared study of G49.5-0.4, or W51A, part of the massive starbirth complex W51. Combining public data from the Spitzer IRAC camera, and Gemini mid-infrared camera T-ReCS at 7.73, 9.69, 12.33, and 24.56 μ m, with a spatial resolution of ∼0.″5, we have identified the mid-infrared counterparts of eight ultracompact H ii regions, showing that two radio sources are deeply embedded in molecular clouds and another is a cloud of ionized gas. From the T-ReCS data we have unveiled the central core of the W51 region, revealing massive young stellar candidates. We modeled the spectral energy distribution of the detected sources. The results suggest that the embedded objects are sources with spectral types ranging from B3 to O5, but the majority of the fits indicate stellar objects with B1 spectral types. We also present an extinction map of IRS 2, showing that a region with lower extinction corresponds to the region where a proposed jet of gas has impacted the foreground cloud. From this map, we also derived the total extinction toward the enigmatic source IRS 2E, which amounts to ∼60 mag in the V band. We calculated the color temperature due to thermal emission of the circumstellar dust of the detected sources; the temperatures are in the interval of ∼100–150 K, which corresponds to the emission of dust located at 0.1 pc from the central source. Finally, we show a possible mid-infrared counterpart of a detected source at millimeter wavelengths that was found by Zapata et al. to be a massive young stellar object undergoing a high accretion rate.

  6. Condicionamento térmico primário de instalações rurais por meio de diferentes tipos de cobertura

    Directory of Open Access Journals (Sweden)

    Thaisa A. Carneiro

    2015-11-01

    Full Text Available RESUMOObjetivou-se, com este trabalho, avaliar o conforto térmico proporcionado por diferentes tipos de cobertura, com base nas análises térmicas e nos índices de conforto térmico humano e zootécnico. A pesquisa foi realizada no período de 20 de março a 29 de maio de 2014, na UFRPE, no município de Recife, PE. Os tipos de cobertura analisados foram: telha de fibrocimento (Tfib, telha reciclada (Trec, telhado verde, grama, Zoysia japonica (Tgra e telhado verde, amendoim, Arachis repens (Tame, com quatro repetições cada um; as variáveis meteorológicas foram registradas interna e externamente aos modelos. A análise térmica das coberturas foi realizada por meio de imagens termográficas e o conforto térmico das instalações foi obtido por meio dos índices de conforto, carga térmica radiante, índice de temperatura de globo negro e umidade, índice de conforto humano, índice de temperatura e umidade e temperatura efetiva. Os telhados verdes (Tame; Tgra reduziram a temperatura da superfície interna das coberturas (5,3 e 4,4 ºC, promoveram maior atenuação da temperatura dos ambientes (1,37 e 1,35 ºC e, consequentemente, promoveram também maior conforto térmico, em comparação com a Tfib e Trec.

  7. Effects of anti-histaminic and anti-cholinergic substances on human thermoregulation during cold provocation.

    Science.gov (United States)

    Tribukait, A; Nobel, G; Mekjavic, I B; Eiken, O

    2010-01-15

    The roles of histaminergic and cholinergic neuron systems in the regulation of body temperature have been studied almost exclusively in animals. Recently, we have found that motion sickness, i.e. a condition where hippocampal cholinergic mismatch signals induce a release of histamine in the vomiting centre, accelerates the decline in body temperature in men during exposure to cold. In the present study we measured the thermoregulatory effects of two substances commonly used against motion sickness, i.e. the histamine (H1) receptor blocker dimenhydrinate (DMH) and the muscarine receptor blocker scopolamine (SCOP). In three trials, control (CN), DMH and SCOP, 10 male subjects were immersed in 15 degrees C water for a maximum of 90 min. The trials were separated by a minimum of three days and their order was alternated between subjects. In all trials the subject received, in a double blind fashion, a transdermal patch (SCOP or placebo) 12-14 h before immersion and a tablet (DMH or placebo) 1h before immersion. Mean skin temperature, rectal temperature (T(rec)), the difference in temperature between the non-immersed right forearm and 3rd finger of the right hand (T(ff)), and oxygen uptake (VO(2)) were recorded. The fall in T(rec) was smaller in the DMH than in the CN and SCOP conditions. The recordings of T(ff) and VO(2) suggest that SCOP attenuates peripheral vasoconstriction while DMH increases shivering thermogenesis. Notably, thermal discomfort was reduced in the SCOP condition. Findings are thoroughly discussed in the context of animal studies on the neuropharmacology and neurophysiology of thermoregulation and motion sickness.

  8. Relieving thermal discomfort: Effects of sprayed L-menthol on perception, performance, and time trial cycling in the heat.

    Science.gov (United States)

    Barwood, M J; Corbett, J; Thomas, K; Twentyman, P

    2015-06-01

    L-menthol stimulates cutaneous thermoreceptors and induces cool sensations improving thermal comfort, but has been linked to heat storage responses; this could increase risk of heat illness during self-paced exercise in the heat. Therefore, L-menthol application could lead to a discrepancy between behavioral and autonomic thermoregulatory drivers. Eight male participants volunteered. They were familiarized and then completed two trials in hot conditions (33.5 °C, 33% relative humidity) where their t-shirt was sprayed with CONTROL-SPRAY or MENTHOL-SPRAY after 10 km (i.e., when they were hot and uncomfortable) of a 16.1-km cycling time trial (TT). Thermal perception [thermal sensation (TS) and comfort (TC)], thermal responses [rectal temperature (Trec ), skin temperature (Tskin )], perceived exertion (RPE), heart rate, pacing (power output), and TT completion time were measured. MENTHOL-SPRAY made participants feel cooler and more comfortable and resulted in lower RPE (i.e., less exertion) yet performance was unchanged [TT completion: CONTROL-SPRAY 32.4 (2.9) and MENTHOL-SPRAY 32.7 (3.0) min]. Trec rate of increase was 1.40 (0.60) and 1.45 (0.40) °C/h after CONTROL-SPRAY and MENTHOL-SPRAY application, which were not different. Spraying L-menthol toward the end of self-paced exercise in the heat improved perception, but did not alter performance and did not increase heat illness risk. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  9. Trehalose Liposomes Suppress the Growth of Tumors on Human Lung Carcinoma-bearing Mice by Induction of Apoptosis In Vivo.

    Science.gov (United States)

    Ichihara, Hideaki; Kuwabara, Keiji; Matsumoto, Yoko

    2017-11-01

    Previous evidence demonstrates that trehalose liposomes (DMTreC14) composed of L-α-dimyristoylphosphatidylcholine (DMPC) and α-D-glycopyranosyl-α-D-glucopyranoside monomyristate (TreC14) inhibit proliferation and invasion on lung carcinoma (A549 cells) in vitro. Here, we aimed to investigate suppressive effects of DMTreC14 on the growth of tumor on human lung carcinoma bearing mice. DMTreC14 composed of 30 mol% DMPC and 70 mol% TreC14 were prepared by the sonication method. Anti-tumor activities of DMTreC14 using the subcutaneous and orthotopic graft-bearing mice of A549 cells were investigated in vivo. The remarkable reduction of volume and weight in subcutaneous tumors on subcutaneous lung carcinoma-bearing mice topically administrated with DMTreC14 were obtained. Apoptotic-positive cells in the subcutaneous tumor slice of subcutaneous lung carcinoma-bearing mice topically administrated with DMTreC14 were observed using TUNEL staining. Lung weights on the orthotopic graft-bearing mice of lung carcinoma intravenously administrated with DMTreC14 were markedly decreased compared to those of the control group. Remarkable decrease in dimensions of tumor area of lung on the orthotopic graft-bearing mice of lung carcinoma intravenously administrated with DMTreC14 was obtained in histological analysis using the hematoxylin and eosin staining. Remarkably high anti-tumor activities of DMTreC14 for the subcutaneous and orthotopic graft-bearing mice of lung carcinoma accompanied with apoptosis were revealed for the first time in vivo. Copyright© 2017, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

  10. Mapping molecular adhesion sites inside SMIL coated capillaries using atomic force microscopy recognition imaging

    Energy Technology Data Exchange (ETDEWEB)

    Leitner, Michael [Institute of Biophysics, Johannes Kepler University Linz, Gruberstrasse 40, 4020 Linz (Austria); Stock, Lorenz G. [Division of Chemistry and Bioanalytics, Department of Molecular Biology, University Salzburg, Hellbrunnerstrasse 34, 5020 Salzburg (Austria); Christian Doppler Laboratory for Innovative Tools for the Characterization of Biosimilars, University Salzburg, Hellbrunnerstrasse 34, 5020 Salzburg (Austria); Traxler, Lukas [Institute of Biophysics, Johannes Kepler University Linz, Gruberstrasse 40, 4020 Linz (Austria); Leclercq, Laurent [Institut des Biomolécules Max Mousseron (IBMM, UMR 5247, CNRS, Université de Montpellier, Ecole Nationale Supérieure de Chimie de Montpellier), Place Eugène Bataillon, CC 1706, 34095 Montpellier (France); Bonazza, Klaus; Friedbacher, Gernot [Institute of Chemical Technologies and Analytics, Vienna University of Technology, Getreidemarkt 9/164, 1060 Vienna (Austria); Cottet, Hervé [Institut des Biomolécules Max Mousseron (IBMM, UMR 5247, CNRS, Université de Montpellier, Ecole Nationale Supérieure de Chimie de Montpellier), Place Eugène Bataillon, CC 1706, 34095 Montpellier (France); Stutz, Hanno [Division of Chemistry and Bioanalytics, Department of Molecular Biology, University Salzburg, Hellbrunnerstrasse 34, 5020 Salzburg (Austria); Christian Doppler Laboratory for Innovative Tools for the Characterization of Biosimilars, University Salzburg, Hellbrunnerstrasse 34, 5020 Salzburg (Austria); Ebner, Andreas, E-mail: andreas.ebner@jku.at [Institute of Biophysics, Johannes Kepler University Linz, Gruberstrasse 40, 4020 Linz (Austria)

    2016-08-03

    Capillary zone electrophoresis (CZE) is a powerful analytical technique for fast and efficient separation of different analytes ranging from small inorganic ions to large proteins. However electrophoretic resolution significantly depends on the coating of the inner capillary surface. High technical efforts like Successive Multiple Ionic Polymer Layer (SMIL) generation have been taken to develop stable coatings with switchable surface charges fulfilling the requirements needed for optimal separation. Although the performance can be easily proven in normalized test runs, characterization of the coating itself remains challenging. Atomic force microscopy (AFM) allows for topographical investigation of biological and analytical relevant surfaces with nanometer resolution and yields information about the surface roughness and homogeneity. Upgrading the scanning tip to a molecular biosensor by adhesive molecules (like partly inverted charged molecules) allows for performing topography and recognition imaging (TREC). As a result, simultaneously acquired sample topography and adhesion maps can be recorded. We optimized this technique for electrophoresis capillaries and investigated the charge distribution of differently composed and treated SMIL coatings. By using the positively charged protein avidin as a single molecule sensor, we compared these SMIL coatings with respect to negative charges, resulting in adhesion maps with nanometer resolution. The capability of TREC as a functional investigation technique at the nanoscale was successfully demonstrated. - Highlights: • SMIL coating allows generation of homogeneous ultra-flat surfaces. • Molecular electrostatic adhesion forces can be determined in the inner wall of CZE capillary with picoNewton accuracy. • Topographical images and simultaneously acquired adhesion maps yield morphological and chemical information at the nanoscale.

  11. Influence of the delivery modus on subpopulations and replication of lymphocytes in mothers and newborns.

    Science.gov (United States)

    Almanzar, Giovanni; Schönlaub, Jörn; Hammerer-Lercher, Angelika; Koppelstaetter, Christian; Bernhard, David; Prelog, Martina

    2015-12-01

    Several studies reported that the mode of delivery may induce changes to the immune system. Our hypothesis was that the delivery mode may influence mainly the naive T cell subpopulation. Particular focus was set on the proportions and peripheral replicative history of naive T cells and cord blood serum concentrations of IL-7, a cytokine involved in peripheral naive T cell homeostasis. In a prospective cohort study, proportions of lymphocyte populations were measured in mothers and newborns delivered by spontaneous vaginal delivery (SD), vacuum extraction (VE), primary (PCS) and secondary Cesarean sections (SCS) by flow cytometry. T-cell-receptor-excision-circles (TRECs) and relative telomere lengths (RTLs) were used to estimate the replicative history of peripheral naive T cells. The cytokine profile was assessed by ELISA. The study demonstrated that leukocytes, neutrophils and NK cells were increased in spontaneously delivered newborns compared to PCS, whereas circulating T cells were relatively lower. TRECs and RTLs were not significantly influenced by the delivery mode. IL-2, IL-8 and IFN-γ were increased in VD. IL-7 production tends to be increased in more stress-associated delivery modes, such as VE and SCS. Our results demonstrate proportional changes in newborns delivered by PCS and diminished cytokine production. It has to be proven whether these alterations may be of disadvantage regarding early defense of infectious diseases. Understanding the physiological role of these changes may help to find preventive strategies for neonatal infectious risks and the development of atopy or other immune diseases. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  12. Citotoxicidad de extractos de plantas medicinales sobre la línea celular de carcinoma de pulmón humano A549 Cytotoxicity of medicinal plant extracts on the human lung carcinoma cell line A549

    Directory of Open Access Journals (Sweden)

    Alexis Díaz García

    2011-03-01

    Full Text Available OBJETIVO: evaluar el efecto de 10 extractos de plantas medicinales sobre el crecimiento de la línea celular humana de carcinoma de pulmón A549. METODOS: el efecto de los extractos sobre la células tumorales se midió a través de un ensayo colorimétrico mediante el empleo del bromuro de 3-(4,5-dimetil-tiazol-2-yl-2,5-difenil tetrazolio a concentraciones entre 3,9-250 µg/mL durante 72 h y se calculó la concentración citotóxica media para cada uno. RESULTADOS: del total de los extractos evaluados solo cuatro (Parthenium hysterophorus, Bixa orellana, Momordica charantia y Cucurbita maxima evidenciaron concentraciones citotóxicas medias inferiores a 100 µg/mL. Excepto Parthenium hysterophorus, las restantes se emplean en la medicina tradicional para el tratamiento del cáncer. Los extractos de Cecropia peltata, Melia azedarach, Annona glabra, Artemisia absintium, Lepidium virginicum y Bidens pilosa no mostraron efectos citotóxicos significativos. CONCLUSIONES: Los extractos de plantas que se emplean en la medicina tradicional para el tratamiento del cáncer, mostraron citotoxicidad sobre las células tumorales. El conocimiento etnobotánico representa una herramienta importante en la selección de plantas medicinales, en la búsqueda de nuevos compuestos para el tratamiento del cáncer.OBJECTIVES: to evaluate the effect of 10 Cuban medicinal plant extracts on the human lung tumor cell line A549. METHODS: the effect of the plant extracts on tumor cells was determined by a colorimetric assay using the 3-(4,5-Dimethylthiazol-2-yl-2,5-diphenyltetrazolium bromide (MTT at concentrations ranging from 3,9-250 µg/mL for 72 hours and the mean cytotoxic concentration was calculated for each of them. RESULTS: the ethanolic extracts of Parthenium hysterophorus, Bixa orellana, Momordica charantia and Cucurbita maxima showed mean cytotoxic concentrations under 100 µg/mL. Except for P. hysterophorus, the others are used in traditional medicine to fight

  13. Espectro polínico de amostras de mel de Apis mellifera L., coletadas na Bahia Pollen spectrum of samples of Apis mellifera L., honey collected in Bahia State, Brazil

    Directory of Open Access Journals (Sweden)

    AUGUSTA CAROLINA DE CAMARGO CARMELLO MORETI

    2000-01-01

    Full Text Available O espectro polínico encontrado em amostras de mel provenientes de seis municípios do Estado da Bahia foi analisado com o objetivo de contribuir para o conhecimento da flora visitada por Apis mellifera L. 1758 (Hymenoptera: ApidaeA identificação dos tipos polínicos foi feita por meio de literatura especializada e de informações de campo. Foram encontrados 43 tipos de pólen, sendo consideradas como dominantes as espécies Eucalyptus sp. (Myrtaceae, Mimosa verrucosa Benth. (Mimosaceae, M. scabrella Benth. (Mimosaceae e Bauhinia sp. (Caesalpiniaceae. Os tipos acessórios foram Alternanthera ficoidea R.Br. (Amaranthaceae, tipo Compositae (Asteraceae e Cecropia sp. (Moraceae. Destacou-se a participação de Mimosa sp. (Mimosaceae e de outras espécies silvestres na composição dos méis nos municípios considerados, registrando-se ainda a espécie Eucalyptus sp. (Myrtaceae como uma das principais fontes de alimento das abelhas dessa região.Pollen spectrum found in honey samples from six localities of Bahia State, Brazil, was analyzed with the objective to contribute for the knowledge of the plants used by Apis mellifera L., 1758 (Hymenoptera: Apidae. The identification of the pollen types was made by specialized literature and by field information. Two hundred pollen grains were studied in order to determine the percentage and the occurrence of each type. Forty three pollen types were identified, being considered as the predominant types Eucalyptus sp. (Myrtaceae, Mimosa verrucosa Benth. (Mimosaceae, M. scabrella Benth. (Mimosaceae and Bauhinia sp. (Caesalpiniaceae. The accessory pollen types were Alternanthera ficoidea R.Br. (Amaranthaceae, Compositae type (Asteraceae and Cecropia sp. (Moraceae. It is intense the participation of Mimosa sp. (Mimosaceae and other wild species in the honey composition of the six localities considered. Eucalyptus sp. (Myrtaceae is one of the dominant sources of bee food in some regions of Bahia State.

  14. Ethnomedicines used in Trinidad and Tobago for urinary problems and diabetes mellitus.

    Science.gov (United States)

    Lans, Cheryl A

    2006-10-13

    This paper is based on ethnobotanical interviews conducted from 1996-2000 in Trinidad and Tobago with thirty male and female respondents. A non-experimental validation was conducted on the plants used for urinary problems and diabetes mellitus: This is a preliminary step to establish that the plants used are safe or effective, to help direct clinical trials, and to inform Caribbean physicians of the plants' known properties to avoid counter-prescribing. The following plants are used to treat diabetes: Antigonon leptopus, Bidens alba, Bidens pilosa, Bixa orellana, Bontia daphnoides, Carica papaya, Catharanthus roseus, Cocos nucifera, Gomphrena globosa, Laportea aestuans, Momordica charantia, Morus alba, Phyllanthus urinaria and Spiranthes acaulis. Apium graviolens is used as a heart tonic and for low blood pressure. Bixa orellana, Bontia daphnoides, Cuscuta americana and Gomphrena globosa are used for jaundice. The following plants are used for hypertension: Aloe vera, Annona muricata, Artocarpus altilis, Bixa orellana, Bidens alba, Bidens pilosa, Bonta daphnoides, Carica papaya, Cecropia peltata, Citrus paradisi, Cola nitida, Crescentia cujete, Gomphrena globosa, Hibiscus sabdariffa, Kalanchoe pinnata, Morus alba, Nopalea cochinellifera, Ocimum campechianum, Passiflora quadrangularis, Persea americana and Tamarindus indicus. The plants used for kidney problems are Theobroma cacao, Chamaesyce hirta, Flemingia strobilifera, Peperomia rotundifolia, Petiveria alliacea, Nopalea cochinellifera, Apium graveolens, Cynodon dactylon, Eleusine indica, Gomphrena globosa, Pityrogramma calomelanos and Vetiveria zizanioides. Plants are also used for gall stones and for cooling. Chamaesyce hirta, Cissus verticillata, Kalanchoe pinnata, Peperomia spp., Portulaca oleraceae, Scoparia dulcis, and Zea mays have sufficient evidence to support their traditional use for urinary problems, "cooling" and high cholesterol. Eggplant extract as a hypocholesterolemic agent has some support but

  15. Ethnomedicines used in Trinidad and Tobago for urinary problems and diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Lans Cheryl A

    2006-10-01

    Full Text Available Abstract Background This paper is based on ethnobotanical interviews conducted from 1996–2000 in Trinidad and Tobago with thirty male and female respondents. Methods A non-experimental validation was conducted on the plants used for urinary problems and diabetes mellitus: This is a preliminary step to establish that the plants used are safe or effective, to help direct clinical trials, and to inform Caribbean physicians of the plants' known properties to avoid counter-prescribing. Results The following plants are used to treat diabetes: Antigonon leptopus, Bidens alba, Bidens pilosa, Bixa orellana, Bontia daphnoides, Carica papaya, Catharanthus roseus, Cocos nucifera, Gomphrena globosa, Laportea aestuans, Momordica charantia, Morus alba, Phyllanthus urinaria and Spiranthes acaulis. Apium graviolens is used as a heart tonic and for low blood pressure. Bixa orellana, Bontia daphnoides, Cuscuta americana and Gomphrena globosa are used for jaundice. The following plants are used for hypertension: Aloe vera, Annona muricata, Artocarpus altilis, Bixa orellana, Bidens alba, Bidens pilosa, Bonta daphnoides, Carica papaya, Cecropia peltata, Citrus paradisi, Cola nitida, Crescentia cujete, Gomphrena globosa, Hibiscus sabdariffa, Kalanchoe pinnata, Morus alba, Nopalea cochinellifera, Ocimum campechianum, Passiflora quadrangularis, Persea americana and Tamarindus indicus. The plants used for kidney problems are Theobroma cacao, Chamaesyce hirta, Flemingia strobilifera, Peperomia rotundifolia, Petiveria alliacea, Nopalea cochinellifera, Apium graveolens, Cynodon dactylon, Eleusine indica, Gomphrena globosa, Pityrogramma calomelanos and Vetiveria zizanioides. Plants are also used for gall stones and for cooling. Conclusion Chamaesyce hirta, Cissus verticillata, Kalanchoe pinnata, Peperomia spp., Portulaca oleraceae, Scoparia dulcis, and Zea mays have sufficient evidence to support their traditional use for urinary problems, "cooling" and high cholesterol

  16. Ethnomedicines used in Trinidad and Tobago for urinary problems and diabetes mellitus

    Science.gov (United States)

    Lans, Cheryl A

    2006-01-01

    Background This paper is based on ethnobotanical interviews conducted from 1996–2000 in Trinidad and Tobago with thirty male and female respondents. Methods A non-experimental validation was conducted on the plants used for urinary problems and diabetes mellitus: This is a preliminary step to establish that the plants used are safe or effective, to help direct clinical trials, and to inform Caribbean physicians of the plants' known properties to avoid counter-prescribing. Results The following plants are used to treat diabetes: Antigonon leptopus, Bidens alba, Bidens pilosa, Bixa orellana, Bontia daphnoides, Carica papaya, Catharanthus roseus, Cocos nucifera, Gomphrena globosa, Laportea aestuans, Momordica charantia, Morus alba, Phyllanthus urinaria and Spiranthes acaulis. Apium graviolens is used as a heart tonic and for low blood pressure. Bixa orellana, Bontia daphnoides, Cuscuta americana and Gomphrena globosa are used for jaundice. The following plants are used for hypertension: Aloe vera, Annona muricata, Artocarpus altilis, Bixa orellana, Bidens alba, Bidens pilosa, Bonta daphnoides, Carica papaya, Cecropia peltata, Citrus paradisi, Cola nitida, Crescentia cujete, Gomphrena globosa, Hibiscus sabdariffa, Kalanchoe pinnata, Morus alba, Nopalea cochinellifera, Ocimum campechianum, Passiflora quadrangularis, Persea americana and Tamarindus indicus. The plants used for kidney problems are Theobroma cacao, Chamaesyce hirta, Flemingia strobilifera, Peperomia rotundifolia, Petiveria alliacea, Nopalea cochinellifera, Apium graveolens, Cynodon dactylon, Eleusine indica, Gomphrena globosa, Pityrogramma calomelanos and Vetiveria zizanioides. Plants are also used for gall stones and for cooling. Conclusion Chamaesyce hirta, Cissus verticillata, Kalanchoe pinnata, Peperomia spp., Portulaca oleraceae, Scoparia dulcis, and Zea mays have sufficient evidence to support their traditional use for urinary problems, "cooling" and high cholesterol. Eggplant extract as a

  17. Vasoactive effects of different fractions from two Panamanians plants used in Amerindian traditional medicine.

    Science.gov (United States)

    Guerrero, Estela I; Morán-Pinzón, Juan A; Ortíz, Luis Gabriel; Olmedo, Dionisio; del Olmo, Esther; López-Pérez, José L; San Feliciano, Arturo; Gupta, Mahabir P

    2010-09-15

    Cecropia obtusifolia (Cecropiaceae) and Psychotria poeppigiana (Synonym: Cephaelis elata, Rubiaceae) are two Latin American plants broadly used in traditional Amerindian medicine. The former, together with many other species of the genus Cecropia, share the folk reputation of curing heart failure, cough, asthma and bronchitis. The latter is used in Panama by Kuna and Ngäbe Buglé (Guaymies) native Indians for the treatment of dyspnea. Based on screening of selected medicinal Panamanian plants by radioligand-binding techniques by Caballero-George et al. (2001), the present study was carried out in order to investigate the vasoactive effects of different fractions from both P. poeppigiana and C. obtusifolia on rat thoracic aorta and identify active fractions and their chemical constituents. Both acid and neutral methanol fractions (P-AMeOH and P-NMeOH) and acid and neutral dichlorometane fractions (P-ADCM and P-NDCM) were obtained from P. poeppigiana crude methanolic and dichlorometane extracts, respectively. Identical fractionation was carried out for C. obtusifolia (C-AMeOH, C-NMeOH, C-ADCM and C-NDCM. Vasorelaxant effect of all fractions, and their inhibition of contractile responses to angiotensin II were evaluated in isolated aortic rings. P-AMeOH, P-NMeOH and P-ADCM fractions induced a concentration-dependent relaxation (43.9+/-1.8%, 35.3+/-4.7% and 52.9+/-3.5%, respectively) in the endothelium-intact aorta precontracted by phenylephrine (PE, 10(-6)M). The relaxation produced by C-AMeOH and C-NMeOH (57.3+/-2.5% and 53.3+/-3.3%, respectively) was greater than the effect produced by C-ADCM and C-NDCM (42.2+/-3.4% and 21.8+/-0.8%, respectively). Only the incubation of the aortic rings with P-AMeOH reduced the maximum contraction induced by angiotensin II at 20.08+/-0.55%. The direct vasorelaxation effect observed could explain in part the ethnomedical use of these plants in Amerindian traditional medicine. The most active fractions contain phenolic and aromatic

  18. Filamentous fungi associated to Bambusa vulgaris var. vulgaris Schrader ex Wendland plantations

    Directory of Open Access Journals (Sweden)

    Mayra Acosta-Suárez

    2011-10-01

    Full Text Available Bambusa vulgaris var. vulgaris Schrader ex Wendland is a species of a great economic importance and in the conservation of soils. Nevertheless, little information exists on the microbial communities associated to its plantations, and their impact on the soil. For that reason it is necessary to identify the cultivable filamentous fungi to understand their roll and contribution to the development of this forest species and their impact in the environment. Considering these criteria the current work had as objectives to quantify, to characterize, to identify and to conserve filamentous fungi in soils cultivated with Bambusa vulgaris var. vulgaris Schrader ex. Wendland. Samples from three soils with plantations of Bambusa vulgaris var. vulgaris Schrader ex Wendland, yagruma (Cecropia peltata L. and eucalyptus (Eucalyptus grandis L. as well as soil without any crop, used as control, were collected for the microbiological analysis. Decimal dilutions of soil were done in Rose Agar Bengal culture medium for strain isolation. The cultural and morphologic characteristics were described. The amount of filamentous fungi oscillated between 103 and 105ufc/g in Bambusa vulgaris var. vulgaris Schrader ex Wendland, similar to the previous registered in plants of yagruma, eucalyptus and in the soil without any crop. A total of 13 generous were identified: Aspergillus, Botryotrichum, Cephalosporium., Cladosporium, Cunningamella, Fusarium, Paecilomyces, Penicillium, Pythium, Pyrenochaeta, Rhizoctonia, Trichocladium and Trichoderma. It was demonstrated that the communities of fungi in plantations of B. vulgaris var. vulgaris Schrader ex Wendland are diverse. Key word: bamboo, filamentous fungi, rhizosphere

  19. Non-experimental validation of ethnoveterinary plants and indigenous knowledge used for backyard pigs and chickens in Trinidad and Tobago.

    Science.gov (United States)

    Lans, C; Georges, K; Brown, G

    2007-06-01

    This paper presents the findings of an exploratory study on ethnoveterinary medicines used for backyard pigs and backyard chickens in Trinidad and Tobago. Research data was collected from 1995 to September 2000. Six plants are used for backyard pigs. Crushed leaves of immortelle (Erythrina pallida, E. micropteryx) are used to remove dead piglets from the uterus. Leaf decoctions of bois canôt (Cecropia peltata) and bamboo (Bambusa vulgaris) are used for labour pains or leaves are fed as a postpartum cleanser. Boiled green papaya fruit (Carica papaya) is fed to pigs to induce milk let-down. The leaves and flowers of male papaya plants (Carica papaya) are fed to deworm pigs. Sour orange juice (Citrus aurantium) is given to pigs to produce lean meat, and coffee grounds are used for scours. Eyebright and plantain leaves (Plantago major) are used for eye injuries of backyard chickens. Worm grass (Chenopodium ambrosioides) and cotton bush (Gossypium species) are used as anthelmintics. Aloe gel (Aloe vera) is used for internal injuries and the yellow sap from the cut Aloe vera leaf or the juice of Citrus limonia is used to purge the birds. A literature review revealed few toxicity concerns and the potential usefulness of the plants.

  20. Polliniferous plants and foraging strategies of Apis mellifera (Hymenoptera: Apidae) in the Yucatán Peninsula, Mexico.

    Science.gov (United States)

    Villanueva, Rogel

    2002-01-01

    A study of the most important polliniferous plants for European and Africanized honeybees (Apis mellifera L.) was made in Quintana Roo state. Comparisons were made between the plants visited by both bee types in order to determine whether there were qualitative or quantitative differences in their choice of plant species. Also some foraging strategies of the honeybees were analysed. Pollen from pollen load samples was acetolysed and mounted on slides. Subsequently the pollen grains were identified, counted and photographed. A total of 206 pollen load samples were collected at Palmas and St. Teresa during two years. The most frequent species in the pollen load samples from European and Africanized honeybees were Cecropia peltata, Metopium brownei, Lonchocarpus sp. 2, Viguiera dentata, Eragrostis sp. 1, Bursera simaruba and Eupatorium albicaule. Both types of honey bees show a high reliance on pollen from only a few species, the first five named above comprised around 50% of all the mean percentage frequencies. Families that contributed with the largest number of pollen species were Fabaceae, Asteraceae, Boraginaceae, Convolvulaceae, Euphorbiaceae, Sapindaceae, Poaceae, Myrtaceae, Sapotaceae and Tiliaceae. C. peltata, Trema micrantha, B. simaruba, Eugenia sp. 1, Thouinia canesceras, Pouteria sp. 1, Mimosa bahamensis and V. dentata, were the pollen species with the largest percentages of occurrence in both European and Africanized bee pollen load samples, and also represent a "long-term" food resources during the year.

  1. Determination index of compatible vegetable species with the lines of electric power transmission

    International Nuclear Information System (INIS)

    Jimenez G, Yulie Andrea; Serna G, Marcela; Lema T, Alvaro; Alvarez D, Esteban; Rincon H, Hernan; Cogollo P, Alvaro

    2004-01-01

    With the purpose of designing methods to clearly identify which plant species generate electrical ground discharges in energy transmission line service corridors and thus avoid the frequent pruning of all Vegetation present in the corridors this study proposes and evaluates compatibility index of plant species with transmission lines, based on six variables: maximum height, growth form, ecological group, life zone, and abundance and frequency of each species. This index was tested in 20 plots of information was collected on all vascular plans present yielding 2147 individuals belonging to 485 species and 105 families, the most discriminating variables in the model were life zone and ecological group, based upon an analysis of principal components. This index applied to the 147 fully identified species with DBH = 2,5 cm showed that Cecropia peltata and Jacaranda copaia were the most problematic species for service lines. Furthermore, a catalogue was developed containing general information and a photographic record of some of the species considered as compatible as a reference for use during maintenance work

  2. Banco de Sementes do Solo de Floresta Restaurada, Reserva Natural Vale, ES

    Directory of Open Access Journals (Sweden)

    Geanna Gonçalves de Souza Correia

    Full Text Available Visando comparar a composição e estrutura do banco de sementes do solo de uma Floresta em Restauração (FR e o de um Ecossistema de Referência (ER foi realizado este estudo, por meio de 60 amostras de 30 cm × 30 cm × 5 cm do solo superficial coletadas na Reserva Natural Vale, Linhares, Espírito Santo. Durante seis meses germinaram indivíduos de 25 espécies e 15 famílias botânicas. Constatou-se elevada densidade de Urochloa decumbens (brachiária na FR, espécie invasora e inibidora do processo de sucessão ecológica, o que representa um problema em casos de possíveis perturbações. Por outro lado, a presença de espécies facilitadoras de sucessão como Cecropia e Trema na FR caracteriza-se de forma positiva, visto que essas espécies são responsáveis pela regeneração florestal pós-distúrbios e não foram utilizadas durante o plantio na área, ou seja, a floresta em restauração está se comportando como um ecossistema que já apresenta resiliência a distúrbios como abertura de clareiras.

  3. Wasps robbing food from ants: a frequent behavior?

    Science.gov (United States)

    Lapierre, Louis; Hespenheide, Henry; Dejean, Alain

    2007-12-01

    Food robbing, or cleptobiosis, has been well documented throughout the animal kingdom. For insects, intrafamilial food robbing is known among ants, but social wasps (Vespidae; Polistinae) taking food from ants has, to the best of our knowledge, never been reported. In this paper, we present two cases involving social wasps robbing food from ants associated with myrmecophytes. (1) Polybioides tabida F. (Ropalidiini) rob pieces of prey from Tetraponera aethiops Smith (Formicidae; Pseudomyrmecinae) specifically associated with Barteria fistulosa Mast. (Passifloraceae). (2) Charterginus spp. (Epiponini) rob food bodies from myrmecophytic Cecropia (Cecropiaceae) exploited by their Azteca mutualists (Formicidae; Dolichoderinae) or by opportunistic ants (that also attack cleptobiotic wasps). We note here that wasps gather food bodies (1) when ants are not yet active; (2) when ants are active, but avoiding any contact with them by flying off when attacked; and (3) through the coordinated efforts of two to five wasps, wherein one of them prevents the ants from leaving their nest, while the other wasps freely gather the food bodies. We suggest that these interactions are more common than previously thought.

  4. Dieta de Traupíneos (Passeriformes, Emberizidae no Parque Estadual do Ibitipoca, Minas Gerais, Brasil Diet of Tanagers (Passeriformes, Emberizidae in Ibitipoca State Park, Minas Gerais, Brazil

    Directory of Open Access Journals (Sweden)

    Marco A. Manhães

    Full Text Available Eleven species of tanagers in Ibitipoca State Park, Minas Gerais, southeastern Brazil, were studied for 12 months and the birds diet was described. Fruits of 52 plant species were the main item consumed for all tanagers, representing 59.70% of all items in 1330 events, although different proportions in the use of this resource have been found among the bird species. The main plant families found were Myrtaceae with eight species accounting for 22.29% (n=177, and Melastomataceae with seven species accounting for 22.29% (n=177 of fruit intake. The most frequent plant species in the diet was Cecropia glaziovi Snethl. (Cecropiaceae, which made up 17.76% (n=141 of fruit intake of all species of tanagers. Arthropod consumption came second with 22.63% (n=301, but flowers, leaves, nectar, food remains left by tourists and galls were also represented. Several environmental features influenced diet composition. An Asteraceae, Vanillosmopsis erythropappa Schultz, very common in the park, was important for some birds as its flowers attracted arthropods and its branches and leaves were used as a substrate for insectivory. Fruit intake rate, some bird-plant interaction and features of food-handling were also discussed, pointing to the importance of these birds for the structure of the heterogeneous local landscape, possibly through the spread of seeds of different plant species.

  5. Catálogo sistemático dos polens das plantas arbóreas do Brasil meridional: XXIII. Moraceae Catalogue of southern Brazilian pollen grains: XXIII. Moraceae

    Directory of Open Access Journals (Sweden)

    Ortrud Monika Barth

    1976-01-01

    Full Text Available Foi estudada a morfologia polínica de espécies pertencentes a oito gêneros. Os diferentes tipos polínicos econtrados, correspondendo aos gêneros, bem como as variações das estruturas dentro de alguns deles, confirmam as relações filogenéticas nesta família. Os de morfologia mais simples correspondem a árvores ou arbustos dos gêneros Brosimum, Cecropia, Chlorophora e Coussapoa, seguindo-se Ficus, Pourouma e Sorocea; os grãos do gênero herbáceo Dorstenia apresentam uma complexa morfologia polínica. A estrutura dos esporodermas e das aberturas dos grãos de pólen comprova o seu relacionamento com outras famílias das Urticales.The pollen morphology from some species of eight genera of Moraceae has been studied. The different pollen types found, corresponding to the genera, as well as the structural variations in some of them, confirm the phylogenetic relations in this family. The specimens with a less complex pollen morphology were the trees or shrubs from the genera Brosimum, Cepropia, Chlorophora and Coussapoa, followed by Ficus, Pourouma and Sorocea; the pollen grains from the herbaceous Dorstenia show a complex pollen morphology. The structures of the sporoderm and the apertures of the pollen grains point out the relationship between these genera and other families from the Urticales.

  6. Holocene Amazon rainforest-savanna dynamics and climatic implications: high-resolution pollen record from Laguna Loma Linda in eastern Colombia

    Science.gov (United States)

    Behling, Hermann; Hooghiemstra, Henry

    2000-10-01

    We present a high-resolution pollen record of a 695-cm-long sediment core from Laguna Loma Linda, located at an altitude of 310 m in the transitional zone between the savannas of the Llanos Orientales and the Amazonian rainforest, about 100 km from the Eastern Cordillera. Based on eight AMS 14C ages, the record represents the last 8700 14C yr BP. During the period from 8700 to 6000 14C yr BP the vegetation was dominated by grass savanna with only a few woody taxa, such as Curatella and Byrsonima, present in low abundance. Gallery forest along the drainage system apparently was poorly developed. Compared with today, precipitation must have been significantly lower and seasonality stronger. During the period from 6000 to 3600 14C yr BP, rainforest taxa increased markedly, reflecting an increase in precipitation. Rainforest and gallery forest taxa such as Moraceae/Urticaceae, Melastomataceae, Alchornea, Cecropia and Acalypha, were abundant, whereas Poaceae were reduced in frequency. From 3600 to 2300 14C yr BP rainforest taxa continued to increase; Moraceae/Urticaceae became very frequent, and Myrtaceae and Myrsine became common. Savanna vegetation decreased continuously. We infer that precipitation was still increasing, and that the length of the annual dry period possibly shortened. From 2300 14C yr BP onwards, grass savanna (mainly represented by Poaceae) expanded and Mauritia palms became frequent. This reflects increased human impact on the vegetation.

  7. Late glacial and Holocene history of the dry forest area in south Colombian Cauca Valley from sites Quilichao and la Teta

    International Nuclear Information System (INIS)

    Berrio, Juan Carlos; Hooghiemstra, Henry; Marchant, Rob; Rangel Orlando

    2002-01-01

    Two sedimentary cores with records of pollen and charcoal content within a chronology provided by radiocarbon are presented from the southern Cauca Valley in Colombia (1020 m). These records document the late glacial and Holocene dry forest vegetation, fire and environment history. Specifically, core Quilichao -1 (640 cm; 3 degrade 6' N, 76 degrade 31' W) represents the periods of 13/150-7720 14 C yr BP and following a hiatus from 2880 14 C yr BP to recent. Core la Teta - 2 (250 cm; 3 degrade 5' N, 76 degrade 32' W) provides a record from 8700 14 C yr BP around 13/150 21 4 C yr BP Quilichao shown an active late glacial drainage system and presence of dry forest. From 11/465-10/520 14 C yr BP dry forest consists mainly of Crotalaria Moraceae Urticaceae, Melastomataceae, Piper and low stature trees, such as Acalypha, Alchornea, Cecropia and Celtis. At higher elevation on the slopes Andean forest with Quercus, Hedyosmum, Myrica and Alnus are common

  8. Tropical rain forest history from the Colombian pacific area: A 4200 - yr pollen record from Laguna Jotardo

    International Nuclear Information System (INIS)

    Berrio, Juan Carlos; Behling, Hermann; Hooghiemstra, Henry

    2002-01-01

    Pollen analysis of a 5-meter long core from Lake Jotardo, located in northern Choco biogeography area (5 degrade 48' N, 76 degrade 42' W) along the pacific coast of Colombia, shows the environmental history of the rain forest during the last 4200 years. Time control has been based on 7 AMS 14 C dates ranging from 4230 to 365 14 C yr BP. The period between 4230 to 4053 14 C yr BP shows sandy deposits and river influence and represents at that time the initial phase of the lake. The composition of the rain forest was different compared to the last 1400 years. Pioneer taxa belonging to Cecropia, Melastomataceae/Combretaceae and Moraceae/Urticaceae dominated the forest. A 30-cm thick organic rich clay from 440 to 410 cm core depth spans a period of f600 years (from 4050 to 1450 14 C yr BP), pointing to a hiatus in the sediment record, possibly caused by riverine erosion of previously deposited sediments. During the last 1400 years rain forest is characterised by Mauritiella, Euterpe/Geonoma, Iriartea, Pachira aquatica and Malpighiaceae. Floral composition of the rain forest is not constant. A biotic dynamics caused changes in the drainage system. The presence of human settlements during the last 1000 yrs is evidenced by Zea Mays and possibly also by the increase of palms

  9. Late Quaternary Vegetation and Climate Change in the Amazon Basin Based on a 50,000 Year Pollen Record from the Amazon Fan, ODP Site 932

    Science.gov (United States)

    Haberle, Simon G.; Maslin, Mark A.

    1999-01-01

    Hemipelagic sediments from the Amazon deep-sea fan, ODP Site 932 (5° 12.7‧N, 47° 1.8‧W), and continental shelf provide a 50,000-yr-long pollen record of Amazon Basin vegetation. The age model for Hole 932A is constrained by eight magnetic remanence intensity features, one paleomagnetic excursion, and three AMS14C dates.Alchornea,Melastomataceae, Myrtaceae, and Moraceae/Urticaceae are dominant taxa in the pollen record between 40,200 and 19,800 cal yr B.P. Andean taxa, such asPodocarpusandHedyosmum,increase in abundance between 19,800 and 11,000 cal yr B.P. and prior to 40,200 cal yr B.P. The Holocene pollen assemblage, derived from Amazon River and continental shelf sediments, is dominated by secondary growth taxa, such asCecropia.Climatic factors influencing the development of glacial and interglacial tropical vegetation are considered by comparing marine with terrestrial records of vegetation change. This comparison shows that the Amazon Basin forests were not extensively replaced by savanna vegetation during the glacial period, contradicting the refugia hypothesis.

  10. Estrutura fitossociológica do componente arbóreo de um fragmento de Floresta Ombrófila Densa na mata sul de Pernambuco, nordeste do Brasil

    Directory of Open Access Journals (Sweden)

    Roberto Felix Costa

    2008-01-01

    Full Text Available This work aimed to describe physiognomy and structure of a Dense Ombrophyllous Forest fragment located in Catende, Pernambuco. All trees with DAP (breast height diameter ≥ 4.77 cm were measured in 40 10 x 25 m plots, systematically installed in five transects. A total of 1049 individuals were observed, distributed in 91 species, 64 genera and 37 botanical families. Mimosaceae and Lauraceae were the families with higher species number, while Anacardiaceae and Moraceae had the highest individuals numbers. Shannon index (H´ was 3.83 nats/ind. Total basal area, height and diameter (average and maximum were 23.59 m²/ha, 13.57 m (± 7.13, 45 m, 13.20 cm (± 10.60 and 127.32 cm, respectively. The species with higher importance values were Tapirira guianensis Aubl., Dialium guianense (Aubl. Sandwith, Helicostylis tomentosa (Poepp. & Endl. Rusby, Thyrsodium spruceanum Benth., Plathymenia foliolosa Benth., Brosimum discolor Schott, Parkia pendula (Willd. Benth. ex Walp., Schefflera morototoni (Aubl. Maguire, Steyerm. & Frodin, Eschweilera ovata (Cambess. Miers and Cecropia palmata Willd. Diametric distribution had an inverted-J-like curve, predicted for a forest unequal in ages in a secondary succession stage.

  11. Citotoxicidad de extractos de plantas medicinales sobre la línea celular de carcinoma de pulmón humano A549

    Directory of Open Access Journals (Sweden)

    Alexis Díaz García

    2011-03-01

    Full Text Available OBJETIVO: evaluar el efecto de 10 extractos de plantas medicinales sobre el crecimiento de la línea celular humana de carcinoma de pulmón A549. METODOS: el efecto de los extractos sobre la células tumorales se midió a través de un ensayo colorimétrico mediante el empleo del bromuro de 3-(4,5-dimetil-tiazol-2-yl-2,5-difenil tetrazolio a concentraciones entre 3,9-250 µg/mL durante 72 h y se calculó la concentración citotóxica media para cada uno. RESULTADOS: del total de los extractos evaluados solo cuatro (Parthenium hysterophorus, Bixa orellana, Momordica charantia y Cucurbita maxima evidenciaron concentraciones citotóxicas medias inferiores a 100 µg/mL. Excepto Parthenium hysterophorus, las restantes se emplean en la medicina tradicional para el tratamiento del cáncer. Los extractos de Cecropia peltata, Melia azedarach, Annona glabra, Artemisia absintium, Lepidium virginicum y Bidens pilosa no mostraron efectos citotóxicos significativos. CONCLUSIONES: Los extractos de plantas que se emplean en la medicina tradicional para el tratamiento del cáncer, mostraron citotoxicidad sobre las células tumorales. El conocimiento etnobotánico representa una herramienta importante en la selección de plantas medicinales, en la búsqueda de nuevos compuestos para el tratamiento del cáncer.

  12. Predation and aggressiveness in host plant protection: a generalization using ants from the genus Azteca

    Science.gov (United States)

    Dejean, Alain; Grangier, Julien; Leroy, Céline; Orivel, Jerôme

    2009-01-01

    In studying the ant genus Azteca, a Neotropical group of arboreal species, we aimed to determine the extent to which the ants use predation and/or aggressiveness to protect their host plants from defoliating insects. We compared a territorially dominant, carton-nester, Azteca chartifex, and three plant-ant species. Azteca alfari and Azteca ovaticeps are associated with the myrmecophyte Cecropia (Cecropiaceae) and their colonies shelter in its hollow branches; whereas Azteca bequaerti is associated with Tococa guianensis (Melastomataceae) and its colonies shelter in leaf pouches situated at the base of the laminas. Whereas A. bequaerti workers react to the vibrations transmitted by the lamina when an alien insect lands on a leaf making it unnecessary for them to patrol their plant, the workers of the three other species rather discover prey by contact. The workers of all four species use a predatory behaviour involving spread-eagling alien insects after recruiting nestmates at short range, and, in some cases, at long range. Because A. alfari and A. ovaticeps discard part of the insects they kill, we deduced that the workers’ predatory behaviour and territorial aggressiveness combine in the biotic defence of their host tree.

  13. The potential sensitivity of tropical plants to increased ultraviolet-B radiation

    International Nuclear Information System (INIS)

    Ziska, L.H.

    1996-01-01

    Little is known concerning the impact of stratospheric ozone depletion and increasing ultraviolet (UV)-B radiation on the phenology and growth of tropical plants. This is because, ostensibly, tropical plants are already exposed to relatively high levels of UV-B radiation (relative to a temperate environment) and should, therefore, possess a greater degree of tolerance to increased UV-B radiation. In this brief review I hope to show that, potentially, direct and indirect effects on photosynthesis, assimilate partitioning, phenology and biomass could occur in both tropical crops (e.g. cassava, rice) and native species (e.g. Cecropia obtusifolia (Bertol. Fl)., Tetramolopium humile (Gray), Nana sandwicensis L.). However, it should be noted that differences in sensitivity to UV-B radiation can be related to experimental conditions, and care should be taken to ensure that the quantity and quality of background solar radiation remains at near ambient conditions. Nevertheless, by integrating current and past studies on the impact of UV-B radiation on tropical species, I hope to be able to demonstrate that photosynthesis, morphology and growth in tropical plants could be directly affected by UV-B radiation and that UV-B radiation may be a factor in species and community dynamics in natural plant populations in the tropics

  14. MANEJO VETERINÁRIO E READAPTAÇÃO ALIMENTAR DE PREGUIÇA-REAL (CHOLOEPUS SP. COM FRATURA DE MANDÍBULA E NECROSE NA LÍNGUA

    Directory of Open Access Journals (Sweden)

    Marcela Miranda Luppi

    2015-07-01

    Full Text Available The case of an adult female of two-toed-sloth (Choloepus sp., victim of running over is described. The animal had jaw fracture and loss of part of the tongue, which hampered their food. Remained under care for ten months, during which treatment with antibiotics and anti-inflammatory were needed and whose doses used were effective. After clinical recovery of the initial condition, the animal still refused any solid food and for three months was fed daily with a liquid diet based on fruits, vegetables, yogurt, ground flaxseed, eggs, flowers and leaves. Gradually came to try to eat sprouts Cecropia sp. and only after eight months spent to feed relatively well alone. Although sloths are considered folivores, the individual has adapted well to the liquid diet, since during the whole process had normal stool consistency and good clinical condition. Despite having spent eight months to readjust to the absence of part of the tongue, it is concluded that all veterinary and feeding management was successful.

  15. Plants used traditionally to treat malaria in Brazil: the archives of Flora Medicinal.

    Science.gov (United States)

    Botsaris, Alexandros S

    2007-05-01

    The archives of Flora Medicinal, an ancient pharmaceutical laboratory that supported ethnomedical research in Brazil for more than 30 years, were searched for plants with antimalarial use. Forty plant species indicated to treat malaria were described by Dr. J. Monteiro da Silva (Flora Medicinal leader) and his co-workers. Eight species, Bathysa cuspidata, Cosmos sulphureus, Cecropia hololeuca, Erisma calcaratum, Gomphrena arborescens, Musa paradisiaca, Ocotea odorifera, and Pradosia lactescens, are related as antimalarial for the first time in ethnobotanical studies. Some species, including Mikania glomerata, Melampodium divaricatum, Galipea multiflora, Aspidosperma polyneuron, and Coutarea hexandra, were reported to have activity in malaria patients under clinical observation. In the information obtained, also, there were many details about the appropriate indication of each plant. For example, some plants are indicated to increase others' potency. There are also plants that are traditionally employed for specific symptoms or conditions that often accompany malaria, such as weakness, renal failure or cerebral malaria. Many plants that have been considered to lack activity against malaria due to absence of in vitro activity against Plasmodium can have other mechanisms of action. Thus researchers should observe ethnomedical information before deciding which kind of screening should be used in the search of antimalarial drugs.

  16. Plants used traditionally to treat malaria in Brazil: the archives of Flora Medicinal

    Directory of Open Access Journals (Sweden)

    Botsaris Alexandros S

    2007-05-01

    Full Text Available Abstract The archives of Flora Medicinal, an ancient pharmaceutical laboratory that supported ethnomedical research in Brazil for more than 30 years, were searched for plants with antimalarial use. Forty plant species indicated to treat malaria were described by Dr. J. Monteiro da Silva (Flora Medicinal leader and his co-workers. Eight species, Bathysa cuspidata, Cosmos sulphureus, Cecropia hololeuca, Erisma calcaratum, Gomphrena arborescens, Musa paradisiaca, Ocotea odorifera, and Pradosia lactescens, are related as antimalarial for the first time in ethnobotanical studies. Some species, including Mikania glomerata, Melampodium divaricatum, Galipea multiflora, Aspidosperma polyneuron, and Coutarea hexandra, were reported to have activity in malaria patients under clinical observation. In the information obtained, also, there were many details about the appropriate indication of each plant. For example, some plants are indicated to increase others' potency. There are also plants that are traditionally employed for specific symptoms or conditions that often accompany malaria, such as weakness, renal failure or cerebral malaria. Many plants that have been considered to lack activity against malaria due to absence of in vitro activity against Plasmodium can have other mechanisms of action. Thus researchers should observe ethnomedical information before deciding which kind of screening should be used in the search of antimalarial drugs.

  17. Soil bacteria associated to Bambusa vulgaris var. vulgaris Schrad. ex Wendl plantations

    Directory of Open Access Journals (Sweden)

    Mileidy Cruz-Martín

    2011-10-01

    Full Text Available It is known that Bambusa vulgaris var. vulgaris is a species that protects the soil and has many other applications. Identifying the microorganisms in their plantations, including bacteria that play a key role are required to demonstrate their impacts on the environment. This work was aimed to quantify, characterize and identify soil bacteria associated to plantations of Bambusa vulgaris var. vulgaris. Soil samples were taken from a plantation of B. vulgaris var. vulgaris with 4 years of culture, Cecropia peltata L. and uncultivated soil as control. To quantify the number of cultivable bacteria present, the plate count method was used in selective culture media for bacteria that fix nitrogen and solubilise phosphorus. Colonies with different cultural characteristics were isolated and a morphological, physiological and cultural characterization was done. As a result, we verified the presence of bacterial communities in similar orders to those found in other species and uncultivated soil. In addition, growth of bacterial colonies was observed in selective culture medium for fixing nitrogen and solubilising phosphorus. Seven strains were identified as Bacillus. The results achieved are a starting point to work on microbial ecology in B. vulgaris var. vulgaris. Keywords: bamboo, microorganism quantification, rhizosphere.

  18. Geographical and Botanical Origin of Apis mellifera (Apidae) Honey in four Colombian Departments

    International Nuclear Information System (INIS)

    Nates Parra, Guiomar; Montoya, Paula Maria; Chamorro, Fermin J; Ramirez, Nedy; Giraldo, Catalina; Obregon, Diana

    2013-01-01

    The aim of this work was to find palynological markers which permit differentiate honeys from the departments of Boyaca, Cundinamarca, Santander and Magdalena, by its geographical and botanical origin. Melissopalynological analyses were made of 184 honey samples obtained from 131 localities. A discriminant analysis and comparisons between the species composition of honey samples were made to find geo-graphical and botanical origin differences. A total of 297 pollen species distributed in 69 families was found, being Mimosa sp., Cecropia sp., Eucalyptus sp., Piper sp. and Quercus humboldtii the most representatives. The major families were Fabaceae, Asteraceae, Myrtaceae, Rubiaceae, Fagaceae and Melastomataceae. Six honey groups differentiated by its geographical origin were found: Altiplano Cundiboyacense, Medio Chicamocha, Sumapaz, Bajo Chicamocha, Sierra Nevada de Santa Marta and Comunera Province. In a broader scale, honeys from the Andean and sub-Andean regions could be differentiated as well. Between the honey types differentiated by its botanical origin, the most important were monofloral honeys of Trifolium pratense, Coffea arabica, Eucalyptus sp., Inga sp. and Heliocarpus americanus, Asteraceae oligofloral honeys and mixtures of Q. humboldtii honeydew and floral nectar (Eucalyptussp., Brassicaceae Type, Asteraceae). This information in addition to the obtained by physico-chemical and sensorial analysis, may be the basis to acquire honeys' origin denomination.

  19. PHYSICOCHEMICAL AND PALYNOLOGYC ANALYSIS OF Apis mellifera l. HONEYBEE COLLECTED FROM SOME EASTERN AND SOUTHWESTERN MUNICIPALITIES OF ANTIOQUIA (COLOMBIA

    Directory of Open Access Journals (Sweden)

    César Augusto Velásquez-Ruiz

    2016-07-01

    Full Text Available In order to determine the honey quality of the species Apis meliferae subspecies scutellata, from some of the Southwestern and Eastern municipalities of Antioquia Department (Colombia, during 2013 and 2015, physicochemical and palynological studies were made in 18 samples. The physicochemical analysis revealed that all analyzed parameters agreed to the established values of the Colombian laws, with few exceptions. Overall the total honeys samples were considered of good quality and minor variations in the analyzed parameters were attributed to the honeys botanical or geographic origin and also errors in the handling processes.  From the palynological view point, most of the samples from southwestern region were unifloral and the Eastern ones were multifloral; total pollen richness was highly variable in both regions, ranging from very poor to very rich samples. The most common taxon in the Eastern region was Asteraceae, followed by Fabaceae, Solanaceae, Myrtaceae (mainly Eucalyptus, Hypochaeris, Borreria and Hedyosmum and in the Southwest, the most abundant taxa were Coffea arabica and Cecropia agustifolia followed by Mimosa, Fabaceae, Cordia, Mangifera indica and Acalypha.

  20. Resistência Natural de Quatro Espécies Florestais Submetidas a Ensaio com Fungos Apodrecedores

    Directory of Open Access Journals (Sweden)

    Douglas Edson Carvalho

    Full Text Available Este estudo teve como objetivo avaliar a durabilidade natural das madeiras de Eucalyptus dunnii, Eucalyptus robusta, Eucalyptus tereticornis e Hovenia dulcis submetidas ao ensaio de apodrecimento acelerado em laboratório com os fungos Gloeophyllum trabeum, causador de podridão parda; e Trametes versicolor, causador de podridão branca. As amostras permaneceram durante 12 semanas em contato com os fungos e após calcularam-se as porcentagens de perda de massa, classificadas quanto ao grau de resistência natural e avaliadas quanto ao índice de susceptibilidade ao ataque. As médias dos resultados foram comparadas pelo teste de Tukey a 5% de significância. A madeira de Eucalyptus robusta foi classificada como resistente e Hovenia dulcis como não resistente para ambos os fungos. O índice de susceptibilidade ao ataque indicou que as espécies estudadas apresentaram valores aceitáveis, sendo mais resistentes ao ataque dos fungos em relação às espécies de referência (Pinus sp.; Cecropia sp..

  1. CARACTERIZACIÓN PALINOLÓGICA DE MIELES DEL APIARIO DEL LABORATORIO DE INVESTIGACIONES MELITOLÓGICAS Y APÍCOLAS DE LA UNIVERSIDAD NACIONAL DE COLOMBIA SEDE MEDELLÍN

    Directory of Open Access Journals (Sweden)

    LUZ OMAIRA VALENCIA CARDONA

    2014-01-01

    Full Text Available Este trabajo presenta la caracterización palinológica de diez (10 muestras de miel de la abeja Apis mellifera de diferentes cosechas de miel del año 2011, tomadas del apiario asociado al Laboratorio de Investigaciones Melitológicas y Apícolas (LIMA de la Universidad Nacional de Colombia, sede Medellín. Las muestras fueron sometidas a tratamiento de acetolisis y montadas en gelatina glicerinada, de acuerdo con procedimientos estándar. El análisis cualitativo y cuantitativo del espectro polínico permitió identificar el 16% del total de los taxa a nivel de especie, 37% fue asociado a un género, 42% a familia y 5% a subfamilia. Los tipos polínicos encontrados en mayor abundancia fueron Eucalyptus spp. (28,7%, Myrtaceae (16%, Lamiaceae/Fraxinus spp (16%, Mimosa spp. (10%, Arecaceae (6,3%, Bignoniaceae (6,3% y Cecropia spp (4,2%. Las mieles del apiario LIMA se consideran multiflorales.

  2. The mode of action of juvenile hormone and ecdysone: towards an epi-endocrinological paradigm?

    Science.gov (United States)

    De Loof, Arnold; Boerjan, Bart; Ernst, Ulrich R; Schoofs, Liliane

    2013-07-01

    In some insect species, two sites of juvenile hormone (JH) synthesis have been reported: the very well documented corpora allata that secrete JH for "general use", and the reproductive system, in particular the male accessory glands, in which the function of the sometimes huge amounts of JH (e.g. in Hyalophora cecropia) remains to be clarified. A recent finding in Schistocerca gregaria, namely that suppression of the ecdysteroid peak preceding a molt by RNAi of the Halloween genes spook, phantom and shade does not impede normal molting, challenges the (never experimentally proven) classical concept that such a peak is causally linked to a molt. Recent developments in epigenetic control of gene expression in both the honey bee and in locusts suggest that, in addition to the classical scheme of hormone-receptor (membrane- and/or nuclear) mode of action, there may be a third way. Upon combining these and other orphan data that do not fit in the commonly accepted textbook schemes, we here advance the working hypothesis that both JH and ecdysone might be important but overlooked players in epigenetic control of gene expression, in particular at extreme concentrations (peak values or total absence). In this review, we put forward how epi-endocrinology can complement classical arthropod endocrinology. Copyright © 2013 Elsevier Inc. All rights reserved.

  3. Medicinal and ethnoveterinary remedies of hunters in Trinidad

    Directory of Open Access Journals (Sweden)

    Georges Karla

    2001-11-01

    Full Text Available Abstract Background Ethnomedicines are used by hunters for themselves and their hunting dogs in Trinidad. Plants are used for snakebites, scorpion stings, for injuries and mange of dogs and to facilitate hunting success. Results Plants used include Piper hispidum, Pithecelobium unguis-cati, Bauhinia excisa, Bauhinia cumanensis, Cecropia peltata, Aframomum melegueta, Aristolochia rugosa, Aristolochia trilobata, Jatropha curcas, Jatropha gossypifolia, Nicotiana tabacum, Vernonia scorpioides, Petiveria alliacea, Renealmia alpinia, Justicia secunda, Phyllanthus urinaria,Phyllanthus niruri,Momordica charantia, Xiphidium caeruleum, Ottonia ovata, Lepianthes peltata, Capsicum frutescens, Costus scaber, Dendropanax arboreus, Siparuma guianensis, Syngonium podophyllum, Monstera dubia, Solanum species, Eclipta prostrata, Spiranthes acaulis, Croton gossypifolius, Barleria lupulina, Cola nitida, Acrocomia ierensis (tentative ID. Conclusion Plant use is based on odour, and plant morphological characteristics and is embedded in a complex cultural context based on indigenous Amerindian beliefs. It is suggested that the medicinal plants exerted a physiological action on the hunter or his dog. Some of the plants mentioned contain chemicals that may explain the ethnomedicinal and ethnoveterinary use. For instance some of the plants influence the immune system or are effective against internal and external parasites. Plant baths may contribute to the health and well being of the hunting dogs.

  4. Medicinal and ethnoveterinary remedies of hunters in Trinidad.

    Science.gov (United States)

    Lans, C; Harper, T; Georges, K; Bridgewater, E

    2001-01-01

    Ethnomedicines are used by hunters for themselves and their hunting dogs in Trinidad. Plants are used for snakebites, scorpion stings, for injuries and mange of dogs and to facilitate hunting success. Plants used include Piper hispidum, Pithecelobium unguis-cati, Bauhinia excisa, Bauhinia cumanensis, Cecropia peltata, Aframomum melegueta, Aristolochia rugosa, Aristolochia trilobata, Jatropha curcas, Jatropha gossypifolia, Nicotiana tabacum, Vernonia scorpioides, Petiveria alliacea, Renealmia alpinia, Justicia secunda, Phyllanthus urinaria,Phyllanthus niruri,Momordica charantia, Xiphidium caeruleum, Ottonia ovata, Lepianthes peltata, Capsicum frutescens, Costus scaber, Dendropanax arboreus, Siparuma guianensis, Syngonium podophyllum, Monstera dubia, Solanum species, Eclipta prostrata, Spiranthes acaulis, Croton gossypifolius, Barleria lupulina, Cola nitida, Acrocomia ierensis (tentative ID). Plant use is based on odour, and plant morphological characteristics and is embedded in a complex cultural context based on indigenous Amerindian beliefs. It is suggested that the medicinal plants exerted a physiological action on the hunter or his dog. Some of the plants mentioned contain chemicals that may explain the ethnomedicinal and ethnoveterinary use. For instance some of the plants influence the immune system or are effective against internal and external parasites. Plant baths may contribute to the health and well being of the hunting dogs.

  5. Correlação entre as atividades antiradical, antiacetilcolinesterase e teor de fenóis totais de extratos de plantas medicinais de farmácias vivas

    Directory of Open Access Journals (Sweden)

    S.M Morais

    2013-01-01

    Full Text Available O objetivo deste trabalho foi avaliar a correlação entre o conteúdo de fenóis de extratos de 18 plantas medicinais comuns nas Farmácias Vivas com a atividade sequestradora do radical livre DPPH e com a inibição da enzima acetilcolinesterase. Maiores conteúdos de fenóis totais foram encontrados nas plantas: Eugenia uniflora, Lippia alba, Lippia microphylla, Mentha x villosa, Ocimum gratissimum e Ocimum selloi. As espécies que apresentaram maior atividade antioxidante, semelhante a quercetina, foram: Spondias mombim, Malphigia glabra, L. alba e Croton zenhtneri,. As plantas Cecropia pachystachia, L. alba, L. microphylla, M. glabra, O. gratissimum e Plectranthus ornatus mostraram maiores halos de inibição da enzima acetilcolinesterase. Combinando as duas ações, as plantas mais ativas foram a M. glabra e a L. alba e somente a segunda correlaciona-se diretamente com o maior teor de fenóis totais. Através deste estudo, M. glabra e L. alba foram consideradas as plantas mais promissoras para estudos subsequentes a fim de encontrar novos compostos com ação potencial contra a doença de Alzheimer.

  6. Arboreal ants use the "Velcro(R principle" to capture very large prey.

    Directory of Open Access Journals (Sweden)

    Alain Dejean

    2010-06-01

    Full Text Available Plant-ants live in a mutualistic association with host plants known as "myrmecophytes" that provide them with a nesting place and sometimes with extra-floral nectar (EFN and/or food bodies (FBs; the ants can also attend sap-sucking Hemiptera for their honeydew. In return, plant-ants, like most other arboreal ants, protect their host plants from defoliators. To satisfy their nitrogen requirements, however, some have optimized their ability to capture prey in the restricted environment represented by the crowns of trees by using elaborate hunting techniques. In this study, we investigated the predatory behavior of the ant Azteca andreae which is associated with the myrmecophyte Cecropia obtusa. We noted that up to 8350 ant workers per tree hide side-by-side beneath the leaf margins of their host plant with their mandibles open, waiting for insects to alight. The latter are immediately seized by their extremities, and then spread-eagled; nestmates are recruited to help stretch, carve up and transport prey. This group ambush hunting technique is particularly effective when the underside of the leaves is downy, as is the case for C. obtusa. In this case, the hook-shaped claws of the A. andreae workers and the velvet-like structure of the underside of the leaves combine to act like natural Velcro that is reinforced by the group ambush strategy of the workers, allowing them to capture prey of up to 13,350 times the mean weight of a single worker.

  7. Palynological Origin, Phenolic Content, and Antioxidant Properties of Honeybee-Collected Pollen from Bahia, Brazil

    Directory of Open Access Journals (Sweden)

    Francisco A. R. Santos

    2012-02-01

    Full Text Available The aim of this study was to determine the palynological origin, phenolic and flavonoid content, and antioxidant properties of twenty-five samples of bee pollen harvested during a nine-month period (February–November from the Canavieiras municipality (northeastern Brazil. Of the 25 samples analyzed, only two (February 01 and 02 were heterofloral. The predominant pollens in the samples analyzed during that month were: Cecropia, Eucalyptus, Elaeis, Mimosa pudica, Eupatorium, and Scoparia. Ethyl acetate fractions were analyzed by HPLC-DAD. The flavonoids isoquercetin, myricetin, tricetin, quercetin, luteolin, selagin, kaempferol, and isorhamnetin were detected. The flavonoid present in all 22 samples was isolated and identified as isorhamnetin 3-O-b-neohesperidoside. The total phenolic contents determined using the Folin-Ciocalteu reagent ranged from 41.5 to 213.2 mg GAE/g. Antioxidant activities based on the 1,1-diphenyl-2-picryl hydrazyl (DPPH, 2,2-azinobis 3-ethylbenzothiozoline-6-sulfonic acid (ABTS, and Fe2+ ion chelating activity assays were observed for all extracts, and correlated with the total phenolic content.

  8. Seed Dispersal by Bats Over Successional Gradients in the Colombian Orinoquia (San Martin, Meta, Colombia

    Directory of Open Access Journals (Sweden)

    Diego Casallas-Pabón

    2017-09-01

    Full Text Available Faunal seed dispersal plays a fundamental role in plant reproduction. Bats are one of the most important seed dispersers in Neotropical ecosystems. The objective of this research was to describe the bat community and seeds that are potentially dispersed in a successional gradient (savanna, woods, forest edge and riparian forest in a locality of the Colombian Altillanura. We measured abundance, richness, and diversity of bats and the seeds found in their feces. 534 individuals belonging to four families and 39 species were captured. The most abundant species were Carollia perspicillata, Artibeus obscurus and Molossus molossus. C. perspicillata and A. obscurus presented the highest values in the seed dispersion index (DII. The records belong to six guilds, the most abundant being frugivores (sedentary and nomadic. The habitat with the greatest bat abundance and richness of species was the forest edge. A total of 11808 seeds with Cecropia engleriana were collected as the most abundant species. Successional states differed significantly in seed abundance but not in wealth, and certain genera showed dominance. Shrubs were highlighted for their dynamic succession and a potential flow of diverse seeds. Here bats play a fundamental role in seed dispersal since those flying over open areas have the same seed load for dispersal as those found in forest, exhibiting a regeneration potential that is contributed to by a bat community having a diverse structure in trophic groups and species.

  9. A LDA-based approach to promoting ranking diversity for genomics information retrieval.

    Science.gov (United States)

    Chen, Yan; Yin, Xiaoshi; Li, Zhoujun; Hu, Xiaohua; Huang, Jimmy Xiangji

    2012-06-11

    In the biomedical domain, there are immense data and tremendous increase of genomics and biomedical relevant publications. The wealth of information has led to an increasing amount of interest in and need for applying information retrieval techniques to access the scientific literature in genomics and related biomedical disciplines. In many cases, the desired information of a query asked by biologists is a list of a certain type of entities covering different aspects that are related to the question, such as cells, genes, diseases, proteins, mutations, etc. Hence, it is important of a biomedical IR system to be able to provide relevant and diverse answers to fulfill biologists' information needs. However traditional IR model only concerns with the relevance between retrieved documents and user query, but does not take redundancy between retrieved documents into account. This will lead to high redundancy and low diversity in the retrieval ranked lists. In this paper, we propose an approach which employs a topic generative model called Latent Dirichlet Allocation (LDA) to promoting ranking diversity for biomedical information retrieval. Different from other approaches or models which consider aspects on word level, our approach assumes that aspects should be identified by the topics of retrieved documents. We present LDA model to discover topic distribution of retrieval passages and word distribution of each topic dimension, and then re-rank retrieval results with topic distribution similarity between passages based on N-size slide window. We perform our approach on TREC 2007 Genomics collection and two distinctive IR baseline runs, which can achieve 8% improvement over the highest Aspect MAP reported in TREC 2007 Genomics track. The proposed method is the first study of adopting topic model to genomics information retrieval, and demonstrates its effectiveness in promoting ranking diversity as well as in improving relevance of ranked lists of genomics search

  10. The impact of immunosenescence on humoral immune response variation after influenza A/H1N1 vaccination in older subjects.

    Directory of Open Access Journals (Sweden)

    Iana H Haralambieva

    Full Text Available Although influenza causes significant morbidity and mortality in the elderly, the factors underlying the reduced vaccine immunogenicity and efficacy in this age group are not completely understood. Age and immunosenescence factors, and their impact on humoral immunity after influenza vaccination, are of growing interest for the development of better vaccines for the elderly.We assessed associations between age and immunosenescence markers (T cell receptor rearrangement excision circles - TREC content, peripheral white blood cell telomerase - TERT expression and CD28 expression on T cells and influenza A/H1N1 vaccine-induced measures of humoral immunity in 106 older subjects at baseline and three timepoints post-vaccination.TERT activity (TERT mRNA expression was significantly positively correlated with the observed increase in the influenza-specific memory B cell ELISPOT response at Day 28 compared to baseline (p-value=0.025. TREC levels were positively correlated with the baseline and early (Day 3 influenza A/H1N1-specific memory B cell ELISPOT response (p-value=0.042 and p-value=0.035, respectively. The expression and/or expression change of CD28 on CD4+ and/or CD8+ T cells at baseline and Day 3 was positively correlated with the influenza A/H1N1-specific memory B cell ELISPOT response at baseline, Day 28 and Day 75 post-vaccination. In a multivariable analysis, the peak antibody response (HAI and/or VNA at Day 28 was negatively associated with age, the percentage of CD8+CD28 low T cells, IgD+CD27- naïve B cells, and percentage overall CD20- B cells and plasmablasts, measured at Day 3 post-vaccination. The early change in influenza-specific memory B cell ELISPOT response was positively correlated with the observed increase in influenza A/H1N1-specific HAI antibodies at Day 28 and Day 75 relative to baseline (p-value=0.007 and p-value=0.005, respectively.Our data suggest that influenza-specific humoral immunity is significantly influenced by

  11. PPARgamma Deficiency Counteracts Thymic Senescence

    Directory of Open Access Journals (Sweden)

    David Ernszt

    2017-11-01

    Full Text Available Thymic senescence contributes to increased incidence of infection, cancer and autoimmunity at senior ages. This process manifests as adipose involution. As with other adipose tissues, thymic adipose involution is also controlled by PPARgamma. This is supported by observations reporting that systemic PPARgamma activation accelerates thymic adipose involution. Therefore, we hypothesized that decreased PPARgamma activity could prevent thymic adipose involution, although it may trigger metabolic adverse effects. We have confirmed that both human and murine thymic sections show marked staining for PPARgamma at senior ages. We have also tested the thymic lobes of PPARgamma haplo-insufficient and null mice. Supporting our working hypothesis both adult PPARgamma haplo-insufficient and null mice show delayed thymic senescence by thymus histology, thymocyte mouse T-cell recombination excision circle qPCR and peripheral blood naive T-cell ratio by flow-cytometry. Delayed senescence showed dose–response with respect to PPARgamma deficiency. Functional immune parameters were also evaluated at senior ages in PPARgamma haplo-insufficient mice (null mice do not reach senior ages due to metabolic adverse affects. As expected, sustained and elevated T-cell production conferred oral tolerance and enhanced vaccination efficiency in senior PPARgamma haplo-insufficient, but not in senior wild-type littermates according to ELISA IgG measurements. Of note, humans also show increased oral intolerance issues and decreased protection by vaccines at senior ages. Moreover, PPARgamma haplo-insufficiency also exists in human known as a rare disease (FPLD3 causing metabolic adverse effects, similar to the mouse. When compared to age- and metabolic disorder-matched other patient samples (FPLD2 not affecting PPARgamma activity, FPLD3 patients showed increased human Trec (hTrec values by qPCR (within healthy human range suggesting delayed thymic senescence, in accordance with

  12. Measuring the Interestingness of Articles in a Limited User Environment

    Energy Technology Data Exchange (ETDEWEB)

    Pon, Raymond K. [Univ. of California, Los Angeles, CA (United States)

    2008-01-01

    Search engines, such as Google, assign scores to news articles based on their relevancy to a query. However, not all relevant articles for the query may be interesting to a user. For example, if the article is old or yields little new information, the article would be uninteresting. Relevancy scores do not take into account what makes an article interesting, which varies from user to user. Although methods such as collaborative filtering have been shown to be effective in recommendation systems, in a limited user environment, there are not enough users that would make collaborative filtering effective. A general framework, called iScore, is presented for defining and measuring the 'interestingness' of articles, incorporating user-feedback. iScore addresses various aspects of what makes an article interesting, such as topic relevancy, uniqueness, freshness, source reputation, and writing style. It employs various methods to measure these features and uses a classifier operating on these features to recommend articles. The basic iScore configuration is shown to improve recommendation results by as much as 20%. In addition to the basic iScore features, additional features are presented to address the deficiencies of existing feature extractors, such as one that tracks multiple topics, called MTT, and a version of the Rocchio algorithm that learns its parameters online as it processes documents, called eRocchio. The inclusion of both MTT and eRocchio into iScore is shown to improve iScore recommendation results by as much as 3.1% and 5.6%, respectively. Additionally, in TREC11 Adaptive Filter Task, eRocchio is shown to be 10% better than the best filter in the last run of the task. In addition to these two major topic relevancy measures, other features are also introduced that employ language models, phrases, clustering, and changes in topics to improve recommendation results. These additional features are shown to improve recommendation results by iScore by

  13. Thermoregulatory and Perceptual Effects of a Percooling Garment Worn Underneath an American Football Uniform.

    Science.gov (United States)

    Keen, Megan L; Miller, Kevin C; Zuhl, Micah N

    2017-11-01

    Keen, ML, Miller, KC, and Zuhl, MN. Thermoregulatory and perceptual effects of a percooling garment worn underneath an American football uniform. J Strength Cond Res 31(11): 2983-2991, 2017-American football athletes are at the highest risk of developing exertional heat illness (EHI). We investigated whether percooling (i.e., cooling during exercise) garments affected perceptual or physiological variables in individuals exercising in the heat while wearing football uniforms. Twelve male participants (age = 24 ± 4 year, mass = 80.1 ± 8.5 kg, height = 182.5 ± 10.4 cm) completed this cross-over, counterbalanced study. On day 1, we measured peak oxygen consumption (V[Combining Dot Above]O2). On days 2 and 3, participants wore percooling garments with (ICE) or without (CON) ice packs over the femoral and brachial arteries. They donned a football uniform and completed 3, 20-minute bouts of treadmill exercise at ∼50% of peak V[Combining Dot Above]O2 (∼33° C, ∼42% relative humidity) followed by a 10-minute rest period. Ice packs were replaced every 20 minutes. Rating of perceived exertion (RPE), thermal sensation, and thirst sensation were measured before and after each exercise bout. Environmental symptoms questionnaire (ESQ) responses and urine specific gravity (Usg) were measured pretesting and after the last exercise bout. V[Combining Dot Above]O2, change in heart rate (ΔHR), and change in rectal temperature (ΔTrec) were measured every 5 minutes. Sweat rate, sweat volume, and percent hypohydration were calculated. No interactions (F17,187 ≤ 1.6, p ≥ 0.1) or main effect of cooling condition (F1,11 ≤ 1.4, p ≥ 0.26) occurred for ΔTrec, ΔHR, thermal sensation, thirst, RPE, ESQ, or Usg. No differences between conditions occurred for sweat volume, sweat rate, or percent hypohydration (t11 ≤ 0.7, p ≥ 0.25). V[Combining Dot Above]O2 differed between conditions over time (F15,165 = 3.3, p football athletes.

  14. Frutos e sementes consumidos pelo tambaqui, Colossoma macrompum (Cuvier, 1818 incorporados em rações: digestibilidade e velocidade de trânsito pelo trato gastrointestinal Fruits and seeds consumed by tambaqui (Colossoma macropomum, CUVIER, 1818 incorporated in the diets: gastrointestinal tract digestibility and transit velocity

    Directory of Open Access Journals (Sweden)

    Jorge Antonio Moreira da Silva

    2003-12-01

    Full Text Available O objetivo do presente trabalho foi estudar o efeito da incorporação de duas espécies de frutos e de duas espécies de sementes em uma dieta referência sobre a digestibilidade dos nutrientes e a velocidade de trânsito do alimento pelo trato gastrointestinal do tambaqui. Utilizando-se uma dieta de referência, 55% do fubá de milho foi substituído, em igual proporção, por farinhas elaboradas a partir do frutos jauari (Astrocaryum jauari e embaúba (Cecropia sp. e das sementes de munguba (Pseudobombax munguba e seringa barriguda (Hevea spruceana. Foram utilizados 15 tanques redondos de cimento amianto de 250 L, com circulação contínua de água e aeração permanente. Sessenta peixes de 1627±112,8 g de peso médio foram distribuídos nas unidades experimentais em grupos de quatro peixes. O delineamento experimental foi o inteiramente casualizado, com cinco tratamentos e três repetições. Os peixes receberam, durante o período experimental, duas refeições diárias, 9 e 16 h, até a saciedade. O tempo de trânsito foi calculado tomando-se o tempo de início da ingestão da dieta (T0 e o tempo do início do aparecimento das primeiras fezes com coloração verde (Tfinal, devido à presença de óxido de cromo (Cr2O3 incluído na ração como indicador inerte. Os peixes foram sacrificados por choque térmico a 4ºC. As amostras foram coletadas no estômago e em três partes do intestino. A incorporação de frutos e sementes alterou significativamente os teores dos nutrientes e os coeficientes de digestibilidade de todas as dietas experimentais. A composição das dietas influenciou significativamente o tempo de trânsito do alimento pelo trato gastrointestinal.A feeding trial was carried out to evaluate nutrient gastrointestinal digestibility and transit velocity in tambaqui fed two species of fruits and two species of seeds incorporated in a reference diet. In the reference diet, 55% of the yellow corn grain was replaced, in equal

  15. Polliniferous plants aud foraging strategles Of Apis mellifera (Hyínenoptera: Apidae in the Yucatán Peninsula, Mexico

    Directory of Open Access Journals (Sweden)

    Rogel Villanueva-G

    2002-12-01

    Full Text Available A study of the most important polliniferous plants for European and Africanized honeybees (Apis mellifera L. was made in Quintana Roo state. Comparisons were made between the plants visited by both bee types in order to determine whether there were qualitative or quantitative differences in their choice of plant species. Also some foraging strategies of the honeybees were analysed. Pollen from pollen load samples was acetolysed and mounted on slides. Subsequently the polien grains were identified, counted and photographed. A total of 206 pollen load samples were collected at Palmas and St. Teresa during two years. The most frequent species in the ponen load samples from European and Africanized honeyhees were Cecropia peltata, Metopium brownei, Lonchocarpus sp. 2, Viguiera dentata, Eragrostis sp. 1, Bursera simaruba and Eupatorium albicaule. Both types of honey bees show a high reliance on pollen from only a few species, the first five named above comprised around 50% of all the mean percentage frequencies. Families that contributed with the largest number of polien species were Fabaceae, Asteraceac, Boraginaceae, Convolvulaecae, Euphorbiaceae, Sapindaceae, Poaceac, Myrtaceae, Sapotaceae and Tiliaceae. C. peltata, Trema micrantha, B. simaruba, Eugenia sp. 1, Thouinia canesceras, Pouteria sp. 1, Mimosa bahamensis and V. dentata, were the pollen species with the largest percentages of oceurrence in both European and Africanized bee pollen load samples, and also represent a "long-term" food resources during the year.Un estudio de las plantas poliníferas más importantes para las abejas europeas y africanizadas (Apis melifera L. se realizó en el estado de Quintana Roo. Se hicieron comparaciones entre plantas visitadas por ambos tipos de abejas, con el objetivo de determinar si hay diferencias cualitativas o cuantitativas en la elección de la especie de planta. Adicionalmente, se analizaron algunas estrategias de forrajeo de las abejas. Muestras

  16. Banco de sementes de remanescentes naturais e de áreas reflorestadas em uma várzea do Rio Mogi-Guaçu - SP Seed bank of natural forest remainders and reforestation areas in a Mogi-Guaçu river floodplain, Luiz Antônio County, São Paulo State, Brazil

    Directory of Open Access Journals (Sweden)

    Assíria Maria Ferreira da Nóbrega

    2009-06-01

    Full Text Available Este estudo avaliou qualitativa e quantitativamente o banco de sementes de dois remanescentes florestais, de um povoamento de Eucalyptus robusta e de três áreas de reflorestamento com espécies nativas, localizados em uma várzea do rio Mogi-Guaçu, Luiz Antônio (21°31´S e 47°55´W, Estado de São Paulo, Brasil. Foram usadas 12 parcelas de 10 x 10 m distribuídas sistematicamente em cada área de estudo. Em cada parcela foram distribuídas aleatoriamente quatro subparcelas de 0,5 m x 0,5 m. Duas subparcelas foram usadas para coletar a serapilheira e duas para coletar o solo a 0-5 cm de profundidade. A amostragem foi realizada em setembro de 2001, nos remanescentes naturais e no povoamento de eucalipto e, em setembro de 2002, nas áreas reflorestadas. As amostras foram acondicionadas em vasos de plástico e incubadas com irrigações periódicas para a germinação das sementes por um período de sete meses, em dois ambientes de casa de vegetação: um a 100% de luz solar e outro sob tela com 70% de redução de luz solar. Na composição do banco de sementes de todas as áreas amostradas, houve predominância de espécies pioneiras dos primeiros estádios de sucessão. As espécies arbóreas mais importantes foram Aloysia virgata e Cecropia hololeuca. Os reflorestamentos com espécies nativas proporcionaram um banco de sementes com maior diversidade de espécies arbóreas nativas do que o povoamento de eucalipto. Este estudo indicou que a similaridade entre as florestas plantadas e as nativas deverá aumentar ao longo do tempo.The objective of this study was to evaluate qualitative and quantitatively the seed bank of two natural forest remainders, one Eucalyptus robusta plantation and three reforestation areas with native species, located in a riparian area of Mogi-Guaçu River floodplain, in Luiz Antonio County (21°31´S and 47°55´W, São Paulo State, Brazil. The evaluation was carried out in 12 plots of 10 x 10 m systematically

  17. Revision of the Neotropical spider genus Gephyroctenus (Araneae: Ctenidae: Calocteninae Revisão do gênero de aranhas neotropicais Gephyroctenus Mello-Leitão (Araneae: Ctenidae: Calocteninae

    Directory of Open Access Journals (Sweden)

    Daniele Polotow

    2008-12-01

    Full Text Available Gephyroctenus Mello-Leitão, 1936 (type species G. philodromoides Mello-Leitão, 1936 is revised. Three species formerly described in this genus are synonymized with species from other genera: G. kolosvaryi Caporiacco, 1947, with Acanthoctenus spinipes Keyserling, 1877, G. parvus Caporiacco, 1947, with Phymatoctenus comosus Simon, 1897, and G. vachoni Caporiacco, 1955, with Caloctenus gracilitarsis Simon, 1897. Eight new species are described: G. portovelho sp. nov., from the States of Rondônia and Amazonas, Brazil; G. divisor sp. nov. and G. acre sp. nov., from the State of Acre, Brazil; G. atininga sp. nov., G. esteio sp. nov. and G. mapia sp. nov., from the State of Amazonas, Brazil; G. juruti sp. nov., from the Department of Loreto, Peru and the State of Pará, Brazil; G. panguana sp. nov., from the Department of Huanuco, Peru. The genus can be distinguished by the presence of a cymbial retrolateral groove, retrolateral origin of embolus, embolus long and thin, median apophysis with a subdistal hook, and hyaline projection close to the embolus base in the male palp and by the fused median and lateral fields in a single epigynal plate, copulatory opening located dorsally in an atrium, and elongated copulatory ducts surrounding the spermathecae in the female epigynum. Field observations on the hunting behavior on ants in trumpet trees (Cecropia are provided for two species, G. philodromoides and G. mapia sp. nov.Gephyroctenus Mello-Leitão, 1936 (espécie-tipo G. philodromoides Mello-Leitão, 1936, é revisado. Três espécies descritas neste gênero são sinonimizadas com espécies de outros gêneros: G. kolosvaryi Caporiacco, 1947, com Acanthoctenus spinipes Keyserling, 1877, G. parvus Caporiacco, 1947, com Phymatoctenus comosus Simon, 1897, e G. vachoni Caporiacco, 1955, com Caloctenus gracilitarsis Simon, 1897. Oito novas espécies são descritas: G. portovelho sp. nov., dos Estados de Rondônia e Amazonas, Brasil; G. divisor sp. nov. e G

  18. Late-glacial and Holocene history of the dry forest area in the south Colombian Cauca Valley

    Science.gov (United States)

    Berrío, Juan Carlos; Hooghiemstra, Henry; Marchant, Robert; Rangel, Orlando

    2002-10-01

    Two sedimentary cores with pollen, charcoal and radiocarbon data are presented. These records document the Late-glacial and Holocene dry forest vegetation, fire and environmental history of the southern Cauca Valley in Colombia (1020 m). Core Quilichao-1 (640 cm; 3° 6N, 76° 31W) represents the periods of 13 150-7720 14C yr BP and, following a hiatus, from 2880 14C yr BP to modern. Core La Teta-2 (250 cm; 3° 5N, 76° 32W) provides a continuous record from 8700 14C yr BP to modern.Around 13 150 14C yr BP core Quilichao-1 shows an active Late-glacial drainage system and presence of dry forest. From 11 465 to 10 520 14C yr BP dry forest consists mainly of Crotalaria, Moraceae/Urticaceae, Melastomataceae/Combretaceae, Piper and low stature trees, such as Acalypha, Alchornea, Cecropia and Celtis. At higher elevation Andean forest comprising Alnus, Hedyosmum, Quercus and Myricacrop taxa (a.o.

  19. INVASIVE WEEDS IN BOGOR BOTANIC GARDENS, INDONESIA AND ITS IMPLICATION ON SURROUNDING LANDSCAPES

    Directory of Open Access Journals (Sweden)

    Edi Santosa

    2014-07-01

    Full Text Available Conservation areas with the objective for collection and exchange plant materials have been speculated as weed bank for surrounding areas. Objective of this study was to identify and characterize ruderal invasive weeds in the Bogor Botanic Gardens (BBG. Observations were conducted in all vak (collection blocks in the BBG in order to identify the weeds species, determine their invasiveness, dominance and distribution. Weeds associations with host plants were observed. Current weed control program and data of dead trees collection were analyzed in relevant to weed. Distribution of weeds outside BBG was observed by transects method following river and road directions. Results showed that there were seven invasive weeds, i.e., Cecropia adenopus (Cecropiaceae, Cissus nodosa Blume (Vitaceae, Cissus sicyoides Blume (Vitaceae, Dioscorea bulbifera L. (Dioscoreaceae, Ficus elastica Roxb. (Moraceae, Mikania micrantha H.B.K. (Asteraceae and Paraserianthes falcataria (L. Nielsen (Fabaceae. These seven weeds species invaded 41 out of 215 plant families in BBG. Six species of weeds, i.e., C. adenopus, C. nodosa Blume., C. sicyoides Blume., D. bulbifera L., M. micrantha H.B.K. and P. falcataria (L. Nielsen, were introduced as BBG collections for the first time while the F. elastica Roxb was considered as native. It is most likely that the weeds dispersal agents are the wind, birds, bats, visitors, and waters. All of these weeds existed in surrounding areas outside BBG. Given the detrimental impact of invasive weeds on the plant collection in BBG, it is necessary to develop long–term comprehensive control measures both inside and neighboring areas by involving other government authorities beyond BBG.

  20. Recovery after 25 years of the tree and palms species diversity on a selectively logged forest in a Venezuelan lowland ecosystem

    Energy Technology Data Exchange (ETDEWEB)

    Lozada, J.R.; Arends, E.; Sánchez, D.; Villarreal, A.; Guevara, J.; Soriano, P.; Costa, M.

    2016-07-01

    Aim of the study: We evaluate palm and tree species diversity in a floodplain forest and the changes affecting the plots subjected to different intensities of selective logging. Area of study: The western alluvial plains of Venezuela. Materials and Methods: A randomized complete blocks design was established 25 years ago with three felling treatments (trees with diameter greater than 20 cm, 40 cm and 60 cm). Each treatment had three replications, using 1 ha permanent plots. We have measured all trees and palms bigger than over 10 cm in diameter. The data set was used to calculate the Importance Value Index of each species, the Shannon-Wiener index, the Hill Numbers and the Chao-Sørensen index. Main results: Disturbance increases the importance value index of pioneer species like Cecropia peltata, Ochroma pyramidale and Triplaris americana. All treatments produce changes on the floristic diversity but most of them are not significant. Only the high impact treatment causes a decrease in the species richness, but after 5 year of recovery this parameter is close to its previous levels (N0= 43.5). In logged forests, species loss (9.2%) is lower than in the control plots (11.7%) and is also lower than the rate of occurrence of species input (14.6%). Research highlights: In these logged forests restoration of diversity is acceptable because is higher than 91% (Chao-Sørensen index). Selective logging, with low and medium intensity, is a disturbance that works in a similar way to natural disturbances. All the diversity indexes recovered the pre-harvest level values. (Author)

  1. Aspectos estructurales y tipos de vegetación de la isla Mocagua, río Amazonas

    Directory of Open Access Journals (Sweden)

    Prieto Adriana

    1995-06-01

    Full Text Available An analysis of some parameters of vegetation structure (coberture -%-, density and specific diversity is presented for plant formations in the Mocagua island (Colombian Amazonia. The structure of the vegetation types ranging from simple river beach zone, aquatic and floodplain environments, to complex arrangement in forest formations. The average number of individuals with DAP > 10 cm (58/0.1 ha is lower than other similar regions. In addition, we describe the types of vegetation founded according with floristic affinities, wich is related to the water content in the sustrata.Tha natural vegetation comprise from aquatic communities of Oxyearyum eubense - Pontederia rotundifolia, to continental ones of Rheedia madruno- Palieourea eroeea, Triehilia pallida - Sommera sabiceoides, phases of Montriehardia arboreseens and Ceeropia latíloba, Paspalum repens and Ceeropia latíloba, and Leptochloa seabra and Torulinium maeroeephalum.Se presentan los resultados de los análisis sobre parámetros estructurales de la vegetación (cobertura-%-, densidad y diversidad específica de las formaciones vegetales de la isla Mocagua (Amazonas, Colombia. La estructura de los tipos de vegetación diferenciados cubre desde los arreglos simples como la de las zonas de playa, ambientes lacustres e inundables, hasta arreglos complejos con diferentes estratos en formaciones boscosas. El número de individuos con DAP > 10 cm (prom.=58/0.1 ha en comparación con los valores en otras zonas es bajo. Los tipos de vegetación descritos obedecen en su distribución esencialmente al contenido de agua en el sustrato; la vegetación natural comprende desde comunidades acuáticas de Oxycaryum cubense - Pontederia rotundifolia, hasta las continentales de Rheedia. madruno - Palieourea eroeea, Triehilia pallida - Sommera sabieeoides y las fases de Montriehardia arboreseens y Ceeropia latiloba, Paspalum repens y Cecropia latiloba, y la de Leptochloa scabra y Torulinium maerocephalum.

  2. ORIGEN GEOGRÁFICO Y BOTÁNICO DE MIELES DE Apis mellifera (APIDAE EN CUATRO DEPARTAMENTOS DE COLOMBIA

    Directory of Open Access Journals (Sweden)

    Guiomar Nates Parra

    2013-09-01

    Full Text Available El objetivo de este trabajo fue determinar marcadores palinológicos que permitieran caracterizar el origen geográfico y botánico de mieles provenientes de los departamentos de Boyacá, Cundinamarca, Santander y Magdalena. Se realizaron análisis melisopalinológicos de 184 muestras de miel procedentes de 131 apiarios. Se determinaron diferencias significativas entre tipos de mieles mediante un análisis discriminante y comparando la composición de especies entre las muestras. En total se encontraron 297 especies distribuidas en 69 familias, dentro de las cuales las más representativas fueron Mimosa sp., Cecropia sp., Eucalyptus sp., Piper sp. y Quercus humboldtii. Las familias más importantes fueron Fabaceae, Asteraceae,Myrtaceae, Rubiaceae, Fagaceae, y Melastomataceae. Se lograron determinar seis grupos de mieles diferenciadas por su origen geográfico: Altiplano Cundiboyacense, Medio Chicamocha, Sumapaz, Bajo Chicamocha, Sierra Nevada de Santa Marta y Provincia Comunera; también se encontraron diferencias entre las mieles de las regiones andinas y subandinas. Dentro de los tipos de mieles diferenciadas por origen botánico predominaron las mieles monoflorales de Trifolium pratense, Coffea arabica, Eucalyptus sp., Inga sp.y Heliocarpus americanus, mieles oligoflorales de asteráceas y mezclas de mielato de Q. humboldtii y néctar floral (Eucalyptus sp. tipo Brassicaceae, asteráceas. La información de este trabajo junto con la obtenida en análisis fisicoquímicos y sensoriales servirá de base para que los apicultores puedan solicitar la denominación de origen de estas mieles.

  3. Holocene History of the Chocó Rain Forest from Laguna Piusbi, Southern Pacific Lowlands of Colombia

    Science.gov (United States)

    Behling, Hermann; Hooghiemstra, Henry; Negret, Alvaro José

    1998-11-01

    A high-resolution pollen record from a 5-m-long sediment core from the closed-lake basin Laguna Piusbi in the southern Colombian Pacific lowlands of Chocó, dated by 11 AMS 14C dates that range from ca. 7670 to 220 14C yr B.P., represents the first Holocene record from the Chocó rain forest area. The interval between 7600 and 6100 14C yr B.P. (500-265 cm), composed of sandy clays that accumulated during the initial phase of lake formation, is almost barren of pollen. Fungal spores and the presence of herbs and disturbance taxa suggest the basin was at least temporarily inundated and the vegetation was open. The closed lake basin might have formed during an earthquake, probably about 4400 14C yr B.P. From the interval of about 6000 14C yr B.P. onwards, 200 different pollen and spore types were identified in the core, illustrating a diverse floristic composition of the local rain forest. Main taxa are Moraceae/Urticaceae, Cecropia,Melastomataceae/Combretaceae, Acalypha, Alchornea,Fabaceae, Mimosa, Piper, Protium, Sloanea, Euterpe/Geonoma, Socratea,and Wettinia.Little change took place during that time interval. Compared to the pollen records from the rain forests of the Colombian Amazon basin and adjacent savannas, the Chocó rain forest ecosystem has been very stable during the late Holocene. Paleoindians probably lived there at least since 3460 14C yr B.P. Evidence of agricultural activity, shown by cultivation of Zea maissurrounding the lake, spans the last 1710 yr. Past and present very moist climate and little human influence are important factors in maintaining the stable ecosystem and high biodiversity of the Chocó rain forest.

  4. Modern pollen-rain characteristics of tall terra firme moist evergreen forest, southern Amazonia

    Science.gov (United States)

    Gosling, William D.; Mayle, Francis E.; Tate, Nicholas J.; Killeen, Timothy J.

    2005-11-01

    The paucity of modern pollen-rain data from Amazonia constitutes a significant barrier to understanding the Late Quaternary vegetation history of this globally important tropical forest region. Here, we present the first modern pollen-rain data for tall terra firme moist evergreen Amazon forest, collected between 1999 and 2001 from artificial pollen traps within a 500 × 20 m permanent study plot (14°34'50″S, 60°49'48″W) in Noel Kempff Mercado National Park (NE Bolivia). Spearman's rank correlations were performed to assess the extent of spatial and inter-annual variability in the pollen rain, whilst statistically distinctive taxa were identified using Principal Components Analysis (PCA). Comparisons with the floristic and basal area data of the plot (stems ≥10 cm d.b.h.) enabled the degree to which taxa are over/under-represented in the pollen rain to be assessed (using R-rel values). Moraceae/Urticaceae dominates the pollen rain (64% median abundance) and is also an important constituent of the vegetation, accounting for 16% of stems ≥10 cm d.b.h. and ca. 11% of the total basal area. Other important pollen taxa are Arecaceae (cf. Euterpe), Melastomataceae/Combretaceae, Cecropia, Didymopanax, Celtis, and Alchornea. However, 75% of stems and 67% of the total basal area of the plot ≥10 cm d.b.h. belong to species which are unidentified in the pollen rain, the most important of which are Phenakospermum guianensis (a banana-like herb) and the key canopy-emergent trees, Erisma uncinatum and Qualea paraensis.

  5. Will rising atmospheric CO2affect leaf litter quality and in situ decomposition rates in native plant communities?

    Science.gov (United States)

    Hirschel, G; Körner, C; Arnone Iii, J A

    1997-04-01

    Though field data for naturally senesced leaf litter are rare, it is commonly assumed that rising atmospheric CO 2 concentrations will reduce leaf litter quality and decomposition rates in terrestrial ecosystems and that this will lead to decreased rates of nutrient cycling and increased carbon sequestration in native ecosystems. We generally found that the quality of␣naturally senesced leaf litter (i.e. concentrations of C, N and lignin; C:N, lignin:N) of a variety of native plant species produced in alpine, temperate and tropical communities maintained at elevated CO 2 (600-680 μl l -1 ) was not significantly different from that produced in similar communities maintained at current ambient CO 2 concentrations (340-355 μl l -1 ). When this litter was allowed to decompose in situ in a humid tropical forest in Panama (Cecropia peltata, Elettaria cardamomum, and Ficus benjamina, 130 days exposure) and in a lowland temperate calcareous grassland in Switzerland (Carex flacca and a graminoid species mixture; 261 days exposure), decomposition rates of litter produced under ambient and elevated CO 2 did not differ significantly. The one exception to this pattern occurred in the high alpine sedge, Carex curvula, growing in the Swiss Alps. Decomposition of litter produced in situ under elevated CO 2 was significantly slower than that of litter produced under ambient CO 2 (14% vs. 21% of the initial litter mass had decomposed over a 61-day exposure period, respectively). Overall, our results indicate that relatively little or no change in leaf litter quality can be expected in plant communities growing under soil fertilities common in many native ecosystems as atmospheric CO 2 concentrations continue to rise. Even in situations where small reductions in litter quality do occur, these may not necessarily lead to significantly slower rates of decomposition. Hence in many native species in situ litter decomposition rates, and the time course of decomposition, may

  6. Leaf litter breakdown rates and associated fauna of native and exotic trees used in Neotropical Riparia Reforestation

    International Nuclear Information System (INIS)

    Gutierrez Isaza, Nataly; Blanco, Juan Felipe

    2014-01-01

    A signature of globalization is the prevalence of exotic trees along reforested urban and rural riparian zones in the neotropics, but little is known about the instream processing of its leaf litter. In this study, leaf litter breakdown rates were measured during 35 days using mesh bags within a reference headwater stream for seven exotic and three native tree species commonly used in urban and rural reforestation. Artocarpus altilis, Schefflera actinophylla and Terminalia catappa scored the highest mass loss rates (>85 %; mean life: t50 <15 d), while Cecropia sp. and Cespedesia macrophylla (mass loss =36 and 15 %; t50 =58 and 172 d, respectively) scored the lowest rates. However, a broad range of rates was observed among the ten species studied. The carbon to phosphorus ratio (c:p) and toughness of the leaf litter were the best predictors of breakdown rates. However, these leaf properties were not correlated with the very low values of macro invertebrates abundance and diversity, and the few morpho classified as shredders. Therefore physical rather than biological controls seem to best explain the observed variability of mass loss rates, and thus slow decomposing leaf litter species seems to provide a habitat rather than a food resource, particularly to collectors. This study suggests that riparian reforestation will propagate species-specific ecological influences on instream processes such as leaf litter processing depending on leaf quality properties, therefore ecosystem-wide influences should be considered for improving reforestation strategies. Future studies should test for differences in breakdown rates and colonization by macro invertebrates relative for leaf litter species origin (native vs. exotic).

  7. Beneficial effect of medicinal plants on the contractility of post-hypoxic isolated guinea pig atria - Potential implications for the treatment of ischemic-reperfusion injury.

    Science.gov (United States)

    Bipat, Robbert; Toelsie, Jerry R; Magali, Indira; Soekhoe, Rubaina; Stender, Karin; Wangsawirana, Angelique; Oedairadjsingh, Krishan; Pawirodihardjo, Jennifer; Mans, Dennis R A

    2016-08-01

    Context Ischemic-reperfusion injury is accompanied by a decreased contractility of the myocardium. Positive-inotropic agents have proven useful for treating this condition but may exert serious side-effects. Objective In this study, aqueous preparations from Abelmoschus esculentus L. Moench (Malvaceae), Annona muricata L. (Annonaceae), Bixa orellana L. (Bixaceae), Cecropia peltata L. (Moraceae), Erythrina fusca Lour. (Fabaceae), Psidium guajava L. (Myrtaceae) and Terminalia catappa L. (Combretaceae) were evaluated for their ability to improve the decreased contractility of isolated guinea pig atria after hypoxic stress. Materials and methods Guinea pig atria isolated in Ringer-Locke buffer gassed with 100% O2 at 30 °C were exposed for 5 min to hypoxia, then allowed to recover in oxygenated buffer alone or containing a single plant extract (0.001-1 mg/mL). The contractility (g/s) and beating frequency (beats/min), as well as troponin C contents of the bathing solution (ng/mL), were determined and expressed as means ± SDs. Results The extracts of A. muricata, B. orellana, C. peltata and T. catappa caused an increase in the contractility compared to untreated atria of 340 ± 102%, 151 ± 13%, 141 ± 14% and 238 ± 44%, respectively. However, the latter two preparations increased the troponin C contents of the bathing solution to 36 ± 11 and 69 ± 33, compared to the value of 11 ± 3 ng/mL found with untreated atria. Conclusions Preparations from A. muricata and B. orellana may possess positive-inotropic properties which may improve the contractility of the post-hypoxic myocardium. Studies to assess their usefulness in ischemic-reperfusion injury are warranted.

  8. Vegetation changes and human impact inferred from an oxbow lake in southwestern Amazonia, Brazil since the 19th century

    Science.gov (United States)

    Rodríguez-Zorro, Paula A.; Enters, Dirk; Hermanowski, Barbara; da Costa, Marcondes Lima; Behling, Hermann

    2015-10-01

    Pollen and X-ray fluorescence spectrometry (XRF) analyses from a 272 cm-long sediment core of Lago Amapá, an oxbow lake in western Amazonia, reveal the first palaeoecological investigation of late Holocene sediments in Acre state, Brazil. Radiocarbon dating of older sediments failed due to re-deposition of organic material but a historical map suggests that lacustrine deposition started at 1900 AD. We detected two periods of changes in sediment and vegetation, dominated by pioneer taxa especially Cecropia. The first period around 1900 AD is documenting an initial oxbow lake, with regular fluvial input (high Ti) and low accumulation of organic matter (low inc/coh ratio). During that period Andean pollen taxa originating from Peruvian Andean headwaters were deposited. A fully lacustrine phase started about 1950 AD and is characterized by prolonged periods of stagnant water (low Fe/Mn ratio). The increase of pioneer taxa, sedimentation rates and a reduction of most of the XRF element counts point to a period during which Lago Amapá was a more isolated lake which was flooded only during exceptional severe flood events and is catching mainly anthropogenic disturbances. The extensive human influence during this period was assumed by 1) the high occurrence of pioneer taxa and the absence of charcoal which could indicate changes in vegetation possibly as a result of logging, 2) the Ca and Ti/K ratio which reflect changes to a local sediment source, and 3) comparison of Landsat images from the last 30 years which shows broad changes in vegetation cover and land transformation in the peripheral areas of the oxbow lake.

  9. Floristic composition and soil fertility in gold mining of Lavrinha, Pontes and Lacerda, MT, Brazil

    Directory of Open Access Journals (Sweden)

    Tatiani Botini Pires

    2011-12-01

    Full Text Available The mining activities cause intense environmental degradation, especially to the soil and vegetation. This study evaluated attributes of floristic composition and soil fertility in areas of open gold mining areas. One hundred plots of 10 × 10 m were distributed in the area effectively mined and in its surroundings. Stem circunference measures (AGC of all identified woody individuals with greater than or equal to 9 cm were taken at 0.3 m height above the ground. In all plots soil samples at 0-20 cm depth were collected for analysis of fertility attributes that are routinely evaluated. In total we observed the occurrence of 92 species and 43 families. The most abundant families were Myrtaceae, Fabaceae and Dilleniaceae; and families that had the greatest numbers of species were Fabaceae (10, Malpighiaceae (7 and Vochysiaceae (5. In the area effectively mined the species with higher importance value index (IVI were Curatella americana (89.1 Cecropia hololeuca (40.9, Roupala montana (12.5 and Pouteria ramiflora (10.2 while in surrounding of the mined area the species with the highest IVI were Myrcia multiflora (25.6, Caryocar brasiliense (15.7, Magonia pubescens (14.8 and Vatareia macrocarpa (14.4. In both areas, the soil had low pH, low availability of P, K+, Ca2+ and Mg2+ and high Al3+ saturation. In spite of the low soil fertility of the studied area, it was able to maintain an overall density of vegetation with AGC > 9 cm of 430 individuals per hectare in the effectively mined area and of 2,220 individuals per hectare in their surroundings.

  10. Measurements of volatile organic compounds emitted from plants in the metropolitan area of São Paulo City , Brazil.

    Science.gov (United States)

    Carvalho, L.; Pisani, S.; Pool, C.; Vasconcellos, P.

    2003-04-01

    The presence of the biogenic hydrocarbons in an NO_x-containing atmosphere can enhance ozone generation and the impact of volatile organic compounds (VOCs) emitted from vegetation on atmospheric chemistry has been investigated. No study of VOC emission rates from plant species has been carried out in São Paulo City, Brazil, prior to this work. This study is part of a three-years project on biogenic volatile organic compounds emissions from species of plants found in the vegetation of the São Paulo metropolitan area. Typical plants (Alchornea sidifolia, Cupania oblongifolia, Cecropia pachystachia, Casearia sylvestris, Machaerium villosum, Croton floribundus, Myrcia rostrata, Solanum erianthum and Ficus insípida) were selected and identical species were studied in urban, sub-urban and forest regions. Biogenic hydrocarbons were determined placing branches of plants in enclosures and measuring the accumulation of emitted compounds in an all-Teflon chamber, the cuvette system. Measuring ambient VOC concentration adsorptive preconcentration, followed by GC-MS after thermal desorption of the sample, was employed to determine components heavier than C_5. Collection of carbonyl compounds on 2, 4-dinitrophenylhydrazine coated particles followed by HPLC-UV was used to analyze low molecular weight carbonyl compounds. Emissions rates of isoprene, a-pinene, camphene and limonene ranged from 0.01 to 2.16 μg C/h.g and emissions rates of aldehydes (C_1 - C_6), acrolein, methacrolein, 2-butanone and acetone ranged from 0.04 to 4.20 μg C/h.g. Ambient and chamber temperatures, relative humidity, light intensity, O_3 and NO_x were monitored during experiments.

  11. Local ecological knowledge and its relationship with biodiversity conservation among two Quilombola groups living in the Atlantic Rainforest, Brazil

    Science.gov (United States)

    Ticktin, Tamara; Fonseca, Amanda Surerus; Macedo, Arthur Ladeira; Orsi, Timothy Ongaro; Chedier, Luciana Moreira; Rodrigues, Eliana; Pimenta, Daniel Sales

    2017-01-01

    Information on the knowledge, uses, and abundance of natural resources in local communities can provide insight on conservation status and conservation strategies in these locations. The aim of this research was to evaluate the uses, knowledge and conservation status of plants in two Quilombolas (descendants of slaves of African origin) communities in the Atlantic rainforest of Brazil, São Sebastião da Boa Vista (SSBV) and São Bento (SB). We used a combination of ethnobotanical and ecological survey methods to ask: 1) What ethnobotanical knowledge do the communities hold? 2) What native species are most valuable to them? 3) What is the conservation status of the native species used? Thirteen local experts described the names and uses of 212 species in SSBV (105 native species) and 221 in SB (96 native species). Shannon Wiener diversity and Pielou’s Equitability indices of ethnobotanical knowledge of species were very high (5.27/0.96 and 5.28/0.96, respectively). Species with the highest cultural significance and use-value indexes in SSBV were Dalbergia hortensis (26/2.14), Eremanthus erythropappus (6.88/1), and Tibouchina granulosa (6.02/1); while Piptadenia gonoacantha (3.32/1), Sparattosperma leucanthum (3.32/1) and Cecropia glaziovii (3.32/0.67) were the highest in SB. Thirty-three native species ranked in the highest conservation priority category at SSBV and 31 at SB. D. hortensis was noteworthy because of its extremely high cultural importance at SSBV, and its categorization as a conservation priority in both communities. This information can be used towards generating sustainable use and conservation plans that are appropriate for the local communities. PMID:29182637

  12. Biodiversidad florística del Jardín Botánico de la Universidad Nacional de Ucayali

    Directory of Open Access Journals (Sweden)

    Víctor Araujo Abanto

    2015-12-01

    Full Text Available El objetivo fue la clasificación taxonómica y descripciones botánicas de 36 especies (23 familias y 33 géneros, árboles, arbustos, lianas y hierbas en el Jardín Botánico y Campus de la Universidad Nacional de Ucayali. De las 36 especies, 6 son ornamentales: Sanchezia tigrina, Crinum augustum, Sansevieria trifasciata, Dracaena fragans, Costus guanaiensis y Vitex cymosa; Rhynchosia phaseoloides cuyas semillas son cotizadas como artesanal; 7 podrían tener uso ornamental: Tabernaemontana heteropylla, Sparattosperma leucanthum, Cayaponia ophthalmica, Gurania eriantha, Gurania spinulosa, Stigmaphyllon florosum y Capirona decorticans; 3 son medicinales: Euphorbia umbellata (tratamiento del cáncer y otros males, Uncaria guianensis (refuerza el sistema inmunológico y Pilocarpus peruvianus contiene Pilocarpina de uso oftalmológico; Pourouma guianensis tiene fuerte olor a mentol; 3 con frutos alimenticios Tamarindus indica, Bunchosia armeniaca y Physalis angulata, conteniendo este último alto contenido en pro vitamina A; 10 son maderables: Dipteryx odorata, Vitex cymosa, Tectona grandis, Ocotea bofo, Perebea xanthochyma, Virola pavonis, Calycophyllum spruceanum, Capirona decorticans, Guazuma ulmifolia y Bambusa arundinacea; Pueraria phaseoloides usado como forraje, en el Jardín Botánico está como maleza al igual que Davilla nítida y Urena lobata, que podría servir como ornamental, su corteza tiene propiedades similares al yute verdadero; Cecropia membranácea, C. concolor, C. sciadophylla y Gouania lupuloides que pueden servir como alimento de la fauna silvestre.

  13. Local ecological knowledge and its relationship with biodiversity conservation among two Quilombola groups living in the Atlantic Rainforest, Brazil.

    Science.gov (United States)

    Conde, Bruno Esteves; Ticktin, Tamara; Fonseca, Amanda Surerus; Macedo, Arthur Ladeira; Orsi, Timothy Ongaro; Chedier, Luciana Moreira; Rodrigues, Eliana; Pimenta, Daniel Sales

    2017-01-01

    Information on the knowledge, uses, and abundance of natural resources in local communities can provide insight on conservation status and conservation strategies in these locations. The aim of this research was to evaluate the uses, knowledge and conservation status of plants in two Quilombolas (descendants of slaves of African origin) communities in the Atlantic rainforest of Brazil, São Sebastião da Boa Vista (SSBV) and São Bento (SB). We used a combination of ethnobotanical and ecological survey methods to ask: 1) What ethnobotanical knowledge do the communities hold? 2) What native species are most valuable to them? 3) What is the conservation status of the native species used? Thirteen local experts described the names and uses of 212 species in SSBV (105 native species) and 221 in SB (96 native species). Shannon Wiener diversity and Pielou's Equitability indices of ethnobotanical knowledge of species were very high (5.27/0.96 and 5.28/0.96, respectively). Species with the highest cultural significance and use-value indexes in SSBV were Dalbergia hortensis (26/2.14), Eremanthus erythropappus (6.88/1), and Tibouchina granulosa (6.02/1); while Piptadenia gonoacantha (3.32/1), Sparattosperma leucanthum (3.32/1) and Cecropia glaziovii (3.32/0.67) were the highest in SB. Thirty-three native species ranked in the highest conservation priority category at SSBV and 31 at SB. D. hortensis was noteworthy because of its extremely high cultural importance at SSBV, and its categorization as a conservation priority in both communities. This information can be used towards generating sustainable use and conservation plans that are appropriate for the local communities.

  14. Variation in crown light utilization characteristics among tropical canopy trees.

    Science.gov (United States)

    Kitajima, Kaoru; Mulkey, Stephen S; Wright, S Joseph

    2005-02-01

    Light extinction through crowns of canopy trees determines light availability at lower levels within forests. The goal of this paper is the exploration of foliage distribution and light extinction in crowns of five canopy tree species in relation to their shoot architecture, leaf traits (mean leaf angle, life span, photosynthetic characteristics) and successional status (from pioneers to persistent). Light extinction was examined at three hierarchical levels of foliage organization, the whole crown, the outermost canopy and the individual shoots, in a tropical moist forest with direct canopy access with a tower crane. Photon flux density and cumulative leaf area index (LAI) were measured at intervals of 0.25-1 m along multiple vertical transects through three to five mature tree crowns of each species to estimate light extinction coefficients (K). Cecropia longipes, a pioneer species with the shortest leaf life span, had crown LAI <0.5. Among the remaining four species, crown LAI ranged from 2 to 8, and species with orthotropic terminal shoots exhibited lower light extinction coefficients (0.35) than those with plagiotropic shoots (0.53-0.80). Within each type, later successional species exhibited greater maximum LAI and total light extinction. A dense layer of leaves at the outermost crown of a late successional species resulted in an average light extinction of 61% within 0.5 m from the surface. In late successional species, leaf position within individual shoots does not predict the light availability at the individual leaf surface, which may explain their slow decline of photosynthetic capacity with leaf age and weak differentiation of sun and shade leaves. Later-successional tree crowns, especially those with orthotropic branches, exhibit lower light extinction coefficients, but greater total LAI and total light extinction, which contribute to their efficient use of light and competitive dominance.

  15. Cardiovascular responses to locomotor activity and feeding in unrestrained three-toed sloths, Bradypus variegatus

    Directory of Open Access Journals (Sweden)

    D.P.F. Duarte

    2004-10-01

    Full Text Available Heart rate (HR and systolic (SBP, diastolic (DBP and mean (MBP blood pressure were recorded by biotelemetry in nine conscious unrestrained sloths for 1 min every 15 min over a 24-h period. The animals were allowed to freely move in an acoustically isolated and temperature-controlled (24 ± 1ºC experimental room with light-dark cycle (12/12 h. Behavior was closely monitored through a unidirectional visor and classified as resting (sitting or suspended, feeding (chewing and swallowing embauba leaves, Cecropia adenops, or locomotor activity around the tree trunk or on the room floor. Locomotor activity caused statistically significant increases in SBP (+8%, from 121 ± 22 to 131 ± 18 mmHg, DBP (+7%, from 86 ± 17 to 92 ± 10 mmHg, MBP (+8%, from 97 ± 19 to 105 ± 12 mmHg, and HR (+14%, from 84 ± 15 to 96 ± 15 bpm compared to resting values, indicating a possible major influence of the autonomic nervous system on the modulation of cardiac function during this behavior. During feeding, the increase in blood pressure was even higher (SBP +27%, from 119 ± 21 to 151 ± 21 mmHg; DBP +21%, from 85 ± 16 to 103 ± 15 mmHg; MBP +24%, from 96 ± 17 to 119 ± 17 mmHg, while HR remained at 14% (from 84 ± 15 to 96 ± 10 bpm above resting values. The proportionally greater increase in blood pressure than in HR during feeding suggests an increase in peripheral vascular resistance as part of the overall response to this behavior.

  16. Effects of insect and decapod exclusion and leaf litter species identity on breakdown rates in a tropical headwater stream

    Directory of Open Access Journals (Sweden)

    José Rincón

    2014-04-01

    Full Text Available La gran variedad de especies vegetales junto a los ríos tropicales afecta la diversidad de detritos orgánicos que llegan a los arroyos, creando variaciones temporales en cantidad y calidad de hojarasca. Examinamos la influencia de las especies vegetales y de la exclusión de macroinvertebrados sobre la descomposición de hojarasca en la parte alta de un arroyo en las montañas Luquillo de Puerto Rico. Incubamos hojarasca de Dacryodes excelsa (Burseraceae, Guarea guidonia (Meliaceae, Cecropia scheberiana (Moraceae, Manilkara bidentata (Sapotaceae y Prestoea acuminata (Palmae en bolsas descomposición que colocamos en una poza de Quebrada Prieta. Usamos bolsas de malla fina para excluir los macroinvertebrados y de malla gruesa para permitir la entrada a crustáceos decápodos (camarones y cangrejos jóvenes e insectos acuáticos (principalmente efemerópteros, quironómidos y tricópteros. D. excelsa y G. guidonia (en ambos tipos de malla tuvieron tasas de descomposición más altas que C. scheberiana, M. bidentata y P. acuminata. La descomposición fue más rápida para todas las especies de hoja con la malla gruesa, resaltando el papel de los descomponedores en este hábitat. Tras 42 días de esta incubación, las densidades totales de invertebrados, efemerópteros y tricópteros fueron mayores en las bolsas con hojas de D. excelsa y G. guidonia, e inferiores en P. acuminata, C. scheberiana y M. bidentata. A mayor densidad de insectos hubo mayor tasa de descomposición. Nuestros resultados indican la importancia de la especie de las hojas y de la presencia de macroinvertebrados en el proceso de descomposición de hojarasca en partes altas de arroyos tropicales.

  17. Secrets of the Sediments: Using ANDRILL's Scientific Adventure on Ice to Transfer Climate Change Science to K-12 Audiences

    Science.gov (United States)

    Huffman, L. T.; Dahlman, L.; Frisch-Gleason, R.; Harwood, D.; Pound, K.; Rack, F.; Riesselman, C.; Trummel, E.; Tuzzi, E.; Winter, D.

    2008-12-01

    Antarctica's harsh environment and the compelling story of living and working there, provides the backdrop for hooking the interest of young learners on science research and the nature of science. By using the adventure stories of today's researcher-explorers, teachers accompanying the ANDRILL team have taken the technical science of drilling rock cores to understand the history of climate change and the advance and retreat of the Antarctic ice sheet, and translated it for non-technical audiences from K-12 school children, to adult community groups. In order to understand the important issues surrounding global climate change, members of the public need access to accurate and relevant information, high quality educational materials, and a variety of learning opportunities in different learning environments. By taking lessons learned from early virtual polar adventure learning expeditions like Will Steger's Trans-Antarctic Expedition, coupled with educators-in-the-field programs like TEA (Teachers Experiencing Antarctica and the Arctic), ARMADA and Polar Trec, ANDRILL's Education and Outreach Program has evolved into successful and far-reaching integrated education projects including 1) the ARISE (ANDRILL Research Immersion for Science Educators) Program, 2) Climate Change Student Summits, 3) the development of Flexhibit (flexible exhibit) teaching resources, 4) virtual online learning communities, and 5) partnering young researchers with teachers and classrooms. Formal evaluations indicate lasting interest in science studies on the part of students and an increase in teachers' scientific background knowledge.

  18. The physical activity climate in Minnesota middle and high schools.

    Science.gov (United States)

    Samuelson, Anne; Lytle, Leslie; Pasch, Keryn; Farbakhsh, Kian; Moe, Stacey; Sirard, John Ronald

    2010-11-01

    This article describes policies, practices, and facilities that form the physical activity climate in Minneapolis/St. Paul, Minnesota metro area middle and high schools and examines how the physical activity climate varies by school characteristics, including public/private, school location and grade level. Surveys examining school physical activity practices, policies and environment were administered to principals and physical education department heads from 115 middle and high schools participating in the Transdisciplinary Research on Energetics and Cancer-Identifying Determinants of Eating and Activity (TREC-IDEA) study. While some supportive practices were highly prevalent in the schools studied (such as prohibiting substitution of other classes for physical education); other practices were less common (such as providing opportunity for intramural (noncompetitive) sports). Public schools vs. private schools and schools with a larger school enrollment were more likely to have a school climate supportive of physical activity. Although schools reported elements of positive physical activity climates, discrepancies exist by school characteristics. Of note, public schools were more than twice as likely as private schools to have supportive physical activity environments. Establishing more consistent physical activity expectations and funding at the state and national level is necessary to increase regular school physical activity.

  19. Paclitaxel stimulates chromosomal fusion and instability in cells with dysfunctional telomeres: Implication in multinucleation and chemosensitization

    Energy Technology Data Exchange (ETDEWEB)

    Park, Jeong-Eun [Division of Radiation Cancer Research, Korea Institute of Radiological and Medical Sciences, Seoul 139-706 (Korea, Republic of); Woo, Seon Rang [Division of Radiation Cancer Research, Korea Institute of Radiological and Medical Sciences, Seoul 139-706 (Korea, Republic of); Department of Biochemistry, College of Medicine, Korea University, Seoul 136-705 (Korea, Republic of); Kang, Chang-Mo [Laboratory of Cytogenetics and Tissue Regeneration, Korea Institute of Radiological and Medical Sciences, Seoul 139-706 (Korea, Republic of); Juhn, Kyoung-Mi; Ju, Yeun-Jin; Shin, Hyun-Jin; Joo, Hyun-Yoo; Park, Eun Ran; Park, In-chul; Hong, Sung Hee; Hwang, Sang-Gu [Division of Radiation Cancer Research, Korea Institute of Radiological and Medical Sciences, Seoul 139-706 (Korea, Republic of); Lee, Jung-Kee [Department of Life Science and Genetic Engineering, Paichai University, Daejeon 302-735 (Korea, Republic of); Kim, Hae Kwon [Department of Biotechnology, Seoul Woman' s University, Seoul 139-774 (Korea, Republic of); Cho, Myung-Haing [Laboratory of Toxicology, College of Veterinary Medicine, Seoul National University, Seoul 151-74-2 (Korea, Republic of); Park, Gil Hong [Department of Biochemistry, College of Medicine, Korea University, Seoul 136-705 (Korea, Republic of); Lee, Kee-Ho, E-mail: khlee@kirams.re.kr [Division of Radiation Cancer Research, Korea Institute of Radiological and Medical Sciences, Seoul 139-706 (Korea, Republic of)

    2011-01-14

    Research highlights: {yields} Paclitaxel serves as a stimulator of chromosomal fusion in cells in which telomeres are dysfunctional. {yields} Typical fusions involve p-arms, but paclitaxel-induced fusions occur between both q- and p-arms. {yields} Paclitaxel-stimulated fusions in cells in which telomeres are dysfunctional evoke prolonged G2/M cell cycle arrest and delay multinucleation. {yields} Upon telomere erosion, paclitaxel promotes chromosomal instability and subsequent apoptosis. {yields} Chromosomal fusion enhances paclitaxel chemosensitivity under telomere dysfunction. -- Abstract: The anticancer effect of paclitaxel is attributable principally to irreversible promotion of microtubule stabilization and is hampered upon development of chemoresistance by tumor cells. Telomere shortening, and eventual telomere erosion, evoke chromosomal instability, resulting in particular cellular responses. Using telomerase-deficient cells derived from mTREC-/-p53-/- mice, here we show that, upon telomere erosion, paclitaxel propagates chromosomal instability by stimulating chromosomal end-to-end fusions and delaying the development of multinucleation. The end-to-end fusions involve both the p- and q-arms in cells in which telomeres are dysfunctional. Paclitaxel-induced chromosomal fusions were accompanied by prolonged G2/M cell cycle arrest, delayed multinucleation, and apoptosis. Telomere dysfunctional cells with mutlinucleation eventually underwent apoptosis. Thus, as telomere erosion proceeds, paclitaxel stimulates chromosomal fusion and instability, and both apoptosis and chemosensitization eventually develop.

  20. A multiple relevance feedback strategy with positive and negative models.

    Directory of Open Access Journals (Sweden)

    Yunlong Ma

    Full Text Available A commonly used strategy to improve search accuracy is through feedback techniques. Most existing work on feedback relies on positive information, and has been extensively studied in information retrieval. However, when a query topic is difficult and the results from the first-pass retrieval are very poor, it is impossible to extract enough useful terms from a few positive documents. Therefore, the positive feedback strategy is incapable to improve retrieval in this situation. Contrarily, there is a relatively large number of negative documents in the top of the result list, and it has been confirmed that negative feedback strategy is an important and useful way for adapting this scenario by several recent studies. In this paper, we consider a scenario when the search results are so poor that there are at most three relevant documents in the top twenty documents. Then, we conduct a novel study of multiple strategies for relevance feedback using both positive and negative examples from the first-pass retrieval to improve retrieval accuracy for such difficult queries. Experimental results on these TREC collections show that the proposed language model based multiple model feedback method which is generally more effective than both the baseline method and the methods using only positive or negative model.

  1. Eukaryotic expression system Pichia pastoris affects the lipase catalytic properties: a monolayer study.

    Directory of Open Access Journals (Sweden)

    Madiha Bou Ali

    Full Text Available Recombinant DNA methods are being widely used to express proteins in both prokaryotic and eukaryotic cells for both fundamental and applied research purposes. Expressed protein must be well characterized to be sure that it retains the same properties as the native one, especially when expressed protein will be used in the pharmaceutical field. In this aim, interfacial and kinetic properties of native, untagged recombinant and tagged recombinant forms of a pancreatic lipase were compared using the monomolecular film technique. Turkey pancreatic lipase (TPL was chosen as model. A kinetic study on the dependence of the stereoselectivity of these three forms on the surface pressure was performed using three dicaprin isomers spread in the form of monomolecular films at the air-water interface. The heterologous expression and the N-His-tag extension were found to modify the pressure preference and decrease the catalytic hydrolysis rate of three dicaprin isomers. Besides, the heterologous expression was found to change the TPL regioselectivity without affecting its stereospecificity contrary to the N-tag extension which retained that regioselectivity and changed the stereospecificity at high surface pressures. The study of parameters, termed Recombinant expression Effects on Catalysis (REC, N-Tag Effects on Catalysis (TEC, and N-Tag and Recombinant expression Effects on Catalysis (TREC showed that the heterologous expression effects on the catalytic properties of the TPL were more deleterious than the presence of an N-terminal tag extension.

  2. Monitoring every last trace

    CERN Multimedia

    CERN Bulletin

    2014-01-01

    The LHC is set to reach a record energy of 6.5 TeV per beam next year and will therefore be producing high energy radiation, as will the injectors supplying it. When exposed to this radiation, some equipment could potentially become radioactive and must therefore be carefully identified and monitored... this is where TREC comes in: software developed by CERN and currently being deployed in our accelerators.   If it becomes slightly radioactive, some of the equipment that makes up CERN’s accelerators may potentially become a hazard to the people who handle or work near it. Even though the risk is usually very low, CERN is obliged to record the location of this equipment, identify it and deal with it in an appropriate manner. During LS1 for example, almost 30,000 radiation protection checks were carried out on more than 2,500 tonnes of equipment! In 2009, going one step further in monitoring this equipment and making the Laboratory even safer, Luca Bruno, then the Radiation Safety Of...

  3. A novel deletion mutation in IL2RG gene results in X-linked severe combined immunodeficiency with an atypical phenotype.

    Science.gov (United States)

    Mou, Wenjun; He, Jianxin; Chen, Xi; Zhang, Hui; Ren, Xiaoya; Wu, Xunyao; Ni, Xin; Xu, Baoping; Gui, Jingang

    2017-01-01

    Severe combined immunodeficiency (SCID) is the most serious disorder among primary immunodeficiency diseases threatening children's life. Atypical SCID variant, presenting with mild reduced T cells subsets, is often associated with infection susceptibility but poor clinical diagnosis. The atypical X-SCID patient in the present study showed a mild clinical presentation with a T low NK + B + immunophenotype. The patient has reduced T- cell subpopulations with a subdued thymic output measured by sjTRECs. Further analysis showed that T cells maintained a normal proliferation and a broad Vβ repertoire. NK cells, however, exhibited a skewed development toward immature CD3 - CD16 + CD56 - cells. Genetic analysis revealed a novel deletion at nucleotide 52 in exon 1 of IL2RG gene. Sequence alignment predicted a truncated IL2RG protein missing signal peptide derived from a possible alternative reading frame. The novel mutation in IL2RG gene identified in our study may help the early diagnosis of atypical X-SCID.

  4. Detection of Sp110 by Flow Cytometry and Application to Screening Patients for Veno-occlusive Disease with Immunodeficiency.

    Science.gov (United States)

    Marquardsen, Florian A; Baldin, Fabian; Wunderer, Florian; Al-Herz, Waleed; Mikhael, Raymond; Lefranc, Gérard; Baz, Zeina; Rezaee, Fariba; Hanna, Rabi; Kfir-Erenfeld, Shlomit; Stepensky, Polina; Meyer, Benedikt; Jauch, Annaise; Bigler, Marc B; Burgener, Anne-Valérie; Higgins, Rebecca; Navarini, Alexander A; Church, Joeseph A; Chou, Janet; Geha, Raif; Notarangelo, Luigi D; Hess, Christoph; Berger, Christoph T; Bloch, Donald B; Recher, Mike

    2017-10-01

    Mutations in Sp110 are the underlying cause of veno-occlusive disease with immunodeficiency (VODI), a combined immunodeficiency that is difficult to treat and often fatal. Because early treatment is critically important for patients with VODI, broadly usable diagnostic tools are needed to detect Sp110 protein deficiency. Several factors make establishing the diagnosis of VODI challenging: (1) Current screening strategies to identify severe combined immunodeficiency are based on measuring T cell receptor excision circles (TREC). This approach will fail to identify VODI patients because the disease is not associated with severe T cell lymphopenia at birth; (2) the SP110 gene contains 17 exons, making it a challenge for Sanger sequencing. The recently developed next-generation sequencing (NGS) platforms that can rapidly determine the sequence of all 17 exons are available in only a few laboratories; (3) there is no standard functional assay to test for the effects of novel mutations in Sp110; and (4) it has been difficult to use flow cytometry to identify patients who lack Sp110 because of the low level of Sp110 protein in peripheral blood lymphocytes. We report here a novel flow cytometric assay that is easily performed in diagnostic laboratories and might thus become a standard assay for the evaluation of patients who may have VODI. In addition, the assay will facilitate investigations directed at understanding the function of Sp110.

  5. Impaired progenitor cell function in HIV-negative infants of HIV-positive mothers results in decreased thymic output and low CD4 counts

    DEFF Research Database (Denmark)

    Nielsen, S. D.; Jeppesen, D. L.; Kolte, L.

    2001-01-01

    Hematologic and immunologic functions were examined in 19 HIV-negative infants of HIV-positive mothers and 19 control infants of HIV-negative mothers. Control infants were selected to match for gestational age, weight, and mode of delivery. Cord blood was obtained from all infants and used for flow...... and fetal thymic organ cultures (FTOCs). Lower naive CD4 counts (459.3 +/- 68.9 vs 1128.9 +/- 146.8 cells/microL, P HIV-positive mothers were found (frequency of CD4(+) cells with TRECs was 3.6% +/- 0.7% compared with 14.3% +/- 2.2% in controls, P ...). In combination with lower red blood cell counts in infants of HIV-positive mothers, this finding suggested impairment of progenitor cell function. Indeed, progenitors from infants of HIV-positive mothers had decreased cloning efficiency (15.7% +/- 2.6% vs 55.8% +/- 15.9%, P =.009) and seemed to generate fewer T...

  6. Improve Biomedical Information Retrieval using Modified Learning to Rank Methods.

    Science.gov (United States)

    Xu, Bo; Lin, Hongfei; Lin, Yuan; Ma, Yunlong; Yang, Liang; Wang, Jian; Yang, Zhihao

    2016-06-14

    In these years, the number of biomedical articles has increased exponentially, which becomes a problem for biologists to capture all the needed information manually. Information retrieval technologies, as the core of search engines, can deal with the problem automatically, providing users with the needed information. However, it is a great challenge to apply these technologies directly for biomedical retrieval, because of the abundance of domain specific terminologies. To enhance biomedical retrieval, we propose a novel framework based on learning to rank. Learning to rank is a series of state-of-the-art information retrieval techniques, and has been proved effective in many information retrieval tasks. In the proposed framework, we attempt to tackle the problem of the abundance of terminologies by constructing ranking models, which focus on not only retrieving the most relevant documents, but also diversifying the searching results to increase the completeness of the resulting list for a given query. In the model training, we propose two novel document labeling strategies, and combine several traditional retrieval models as learning features. Besides, we also investigate the usefulness of different learning to rank approaches in our framework. Experimental results on TREC Genomics datasets demonstrate the effectiveness of our framework for biomedical information retrieval.

  7. Anaerobic performance when rehydrating with water or commercially available sports drinks during prolonged exercise in the heat.

    Science.gov (United States)

    Coso, Juan Del; Estevez, Emma; Baquero, Raúl Antonio; Mora-Rodriguez, Ricardo

    2008-04-01

    The effects that rehydrating drinks ingested during exercise may have on anaerobic exercise performance are unclear. This study aimed to determine which of four commercial rehydrating drinks better maintains leg power and force during prolonged cycling in the heat. Seven endurance-trained and heat-acclimatized cyclists pedaled for 120 min at 63% maximum oxygen consumption in a hot, dry environment (36 degrees C; 29% humidity, 1.9 m.s-1 airflow). In five randomized trials, during exercise, subjects drank 2.4 +/- 0.1 L of (i) mineral water (WAT; San Benedetto), (ii) 6% carbohydrate-electrolyte solution (Gatorade lemon), (iii) 8% carbohydrate-electrolyte solution (Powerade Citrus Charge), (iv) 8% carbohydrate-electrolyte solution with lower sodium concentration than other sports drinks (Aquarius orange), or (v) did not ingest any fluid (DEH). Fluid balance, rectal temperature (Trec), maximal cycling power (Pmax), and leg maximal voluntary isometric contraction (MVC) were measured. During DEH, subjects lost 3.7 +/- 0.2% of initial body mass, whereas subjects lost only 0.8% +/- 0.1% in the other trials (p sports drinks during prolonged exercise in the heat preserves leg force, whereas rehydrating with water does not. However, low sodium concentration in a sports drink seems to preclude its ergogenic effects on force.

  8. VizieR Online Data Catalog: Mid-infrared-X-ray correlation for local AGNs (Asmus+, 2015)

    Science.gov (United States)

    Asmus, D.; Gandhi, P.; Honig, S. F.; Smette, A.; Duschl, W. J.

    2018-01-01

    We start with the total sample from the AGN MIR atlas of 253 objects (Asmus et al. 2014, J/MNRAS/439/1648). Note that sample is a combination of a hard X-ray (14-195 keV) selected and a quasi-MIR selected sample as explained in Asmus et al. (2014, J/MNRAS/439/1648). The MIR continuum fluxes are the unresolved nuclear fluxes extracted from ground-based multifilter photometry obtained with the instruments VISIR (Lagage et al. 2004Msngr.117...12L), T-ReCS (Telesco et al. 1998SPIE.3354..534T), Michelle (Glasse, Atad-Ettedgui & Harris 1997SPIE.2871.1197G), and COMICS; (Kataza et al. 2000SPIE.4008.1144K). We collect observed 14-195 keV fluxes, Fobs(14-195 keV), measured with Swift/BAT (Burst Alert Telescope) by combining the data of the 54 and 70 month source catalogues with preference for the latter (Cusumano et al. 2010, J/A+A/524/A64; Baumgartner et al. 2013, J/ApJS/207/19). (2 data files).

  9. Deinococcus gobiensis cold shock protein improves salt stress tolerance of escherichia coli

    International Nuclear Information System (INIS)

    Jiang Shijie; Wang Jin; Yang Mingkun; Chen Ming; Zhang Wei; Luo Xuegang

    2013-01-01

    The Deinococcus gobiensis I-0, an extremely radiation-resistant bacterium, isolated from the Gobi, has superior resistance to abiotic stress (e.g radiation, oxidation, dehydration and so on). The two cold-shock proteins encoded by csp1 (Dgo C A1136) and csp2 (Dgo P A0041) were identified in the complete genome sequence of D. gobiensis. In this study, we showed that D. gobiensis Csp1 protected Escherichia coli cells against cold shock and other abiotic stresses such as salt and osmotic shocks. The quantitative real-time PCR assay shows that the expression of trehalose synthase (otsA, otsB) was up-regulated remarkably under salt stress in the csp1-expressing strain, while no difference in the expression of the genes involved in trehalose degradation (treB and treC). The results suggested that Csp1 caused the accumulation of the trehalose was a major feature for improving tolerance to salt stress in E. coli. (authors)

  10. The Impact of Scientist-Educator Collaborations: an early-career scientist's perspective

    Science.gov (United States)

    Roop, H. A.

    2017-12-01

    A decade ago, a forward-thinking faculty member exposed a group of aspiring scientists to the impacts and career benefits of working directly with K-12 students and educators. Ten years later, as one of those young scientists, it is clear that the relationships born out of this early experience can transform a researcher's impact and trajectory in science. Connections with programs like the NSF-funded PolarTREC program, the teacher-led Scientists in the Classroom effort, and through well-coordinated teacher training opportunities there are clear ways in which these partnerships can a) transform student learning; b) serve as a powerful and meaningful way to connect students to authentic research and researchers; and c) help researchers become more effective communicators by expanding their ability to connect their work to society. The distillation of science to K-12 students, with the expert eye of educators, makes scientists better at their work with tangible benefits to skills that matter in academia - securing funding, writing and communicating clearly and having high-value broader impacts. This invited abstract is submitted as part of this session's panel discussion and will explore in detail, with concrete examples, the mutual benefits of educator-scientist partnerships and how sustained engagement can transform the reach, connection and application of research science.

  11. Newborn Screening for Severe Combined Immunodeficiency in Israel

    Directory of Open Access Journals (Sweden)

    Erez Rechavi

    2017-06-01

    Full Text Available Newborn screening (NBS programs for severe combined immunodeficiency (SCID, the most severe type of primary immunodeficiency, are being implemented in more and more countries with every passing year. Since October 2015, SCID screening via T cell receptor excision circle (TREC quantification in dried blood spots (DBS has been part of the Israeli NBS program. As an NBS program in its infancy, SCID screening is still evolving, making gathering input from the various programs crucial for compiling an ideal screening algorithm. The relatively high rate of consanguineous marriages in Israel, especially among non-Jews, correlates with an increased incidence of SCID. The Israeli algorithm uses a commercial kit and consists of a two-Guthrie card confirmation system prior to referral to a national immunology center. Preliminary data from the first year and a half of SCID screening in Israel has identified a surprisingly high prevalence of DNA cross-link repair protein 1c (DCLRE1C; ARTEMIS mutations as the cause of SCID in Israel. The clinically unbiased nature of SCID screening helps unearth mild/leaky SCID phenotypes, resulting in a better understanding of true SCID prevalence and etiology.

  12. Tracking Multiple Topics for Finding Interesting Articles

    Energy Technology Data Exchange (ETDEWEB)

    Pon, R K; Cardenas, A F; Buttler, D J; Critchlow, T J

    2008-01-03

    We introduce multiple topic tracking (MTT) for iScore to better recommend news articles for users with multiple interests and to address changes in user interests over time. As an extension of the basic Rocchio algorithm, traditional topic detection and tracking, and single-pass clustering, MTT maintains multiple interest profiles to identify interesting articles for a specific user given user-feedback. Focusing on only interesting topics enables iScore to discard useless profiles to address changes in user interests and to achieve a balance between resource consumption and classification accuracy. iScore is able to achieve higher quality results than traditional methods such as the Rocchio algorithm. We identify several operating parameters that work well for MTT. Using the same parameters, we show that MTT alone yields high quality results for recommending interesting articles from several corpora. The inclusion of MTT improves iScore's performance by 25% in recommending news articles from the Yahoo! News RSS feeds and the TREC11 adaptive filter article collection. And through a small user study, we show that iScore can still perform well when only provided with little user feedback.

  13. What Can Pictures Tell Us About Web Pages? Improving Document Search Using Images.

    Science.gov (United States)

    Rodriguez-Vaamonde, Sergio; Torresani, Lorenzo; Fitzgibbon, Andrew W

    2015-06-01

    Traditional Web search engines do not use the images in the HTML pages to find relevant documents for a given query. Instead, they typically operate by computing a measure of agreement between the keywords provided by the user and only the text portion of each page. In this paper we study whether the content of the pictures appearing in a Web page can be used to enrich the semantic description of an HTML document and consequently boost the performance of a keyword-based search engine. We present a Web-scalable system that exploits a pure text-based search engine to find an initial set of candidate documents for a given query. Then, the candidate set is reranked using visual information extracted from the images contained in the pages. The resulting system retains the computational efficiency of traditional text-based search engines with only a small additional storage cost needed to encode the visual information. We test our approach on one of the TREC Million Query Track benchmarks where we show that the exploitation of visual content yields improvement in accuracies for two distinct text-based search engines, including the system with the best reported performance on this benchmark. We further validate our approach by collecting document relevance judgements on our search results using Amazon Mechanical Turk. The results of this experiment confirm the improvement in accuracy produced by our image-based reranker over a pure text-based system.

  14. Improving the text classification using clustering and a novel HMM to reduce the dimensionality.

    Science.gov (United States)

    Seara Vieira, A; Borrajo, L; Iglesias, E L

    2016-11-01

    In text classification problems, the representation of a document has a strong impact on the performance of learning systems. The high dimensionality of the classical structured representations can lead to burdensome computations due to the great size of real-world data. Consequently, there is a need for reducing the quantity of handled information to improve the classification process. In this paper, we propose a method to reduce the dimensionality of a classical text representation based on a clustering technique to group documents, and a previously developed Hidden Markov Model to represent them. We have applied tests with the k-NN and SVM classifiers on the OHSUMED and TREC benchmark text corpora using the proposed dimensionality reduction technique. The experimental results obtained are very satisfactory compared to commonly used techniques like InfoGain and the statistical tests performed demonstrate the suitability of the proposed technique for the preprocessing step in a text classification task. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  15. Energy extraction and water treatment in one system: The idea of using a desalination battery in a cooling tower

    Science.gov (United States)

    Shapira, Barak; Cohen, Izaak; Penki, Tirupathi Rao; Avraham, Eran; Aurbach, Doron

    2018-02-01

    The use of sodium manganese oxide as an intercalation electrode for water treatment was recently explored, and referred to as a "desalination battery" and "hybrid capacitive deionization". Here, we examine the feasibility of using such a desalination battery, comprising crystalline Na4Mn9O18 as the cathode and Ag/AgCl/Cl- electrode as the anode, to extract energy from low-grade waste heat sources. Sodium manganese oxide electrode's material was produced via a solid-state synthesis. Electrodes were produced by spray-coated onto graphite foils, and showed a temperature dependence of the electrode potential, namely, ∂ E / ∂ T , of -0.63 mV/K (whereas, the Ag/AgCl/Cl- mesh electrode showed much lower temperature dependence, energy conversion, a flow battery system was constructed. Thermally regenerative electrochemical cycles (TREC) were constructed for the flow battery cell. The thermal energy conversion, in this particular system, was shown to be feasible at relatively low C-rate (C/19) with temperatures varying between 30 °C and 70 °C.

  16. A multiple relevance feedback strategy with positive and negative models.

    Science.gov (United States)

    Ma, Yunlong; Lin, Hongfei

    2014-01-01

    A commonly used strategy to improve search accuracy is through feedback techniques. Most existing work on feedback relies on positive information, and has been extensively studied in information retrieval. However, when a query topic is difficult and the results from the first-pass retrieval are very poor, it is impossible to extract enough useful terms from a few positive documents. Therefore, the positive feedback strategy is incapable to improve retrieval in this situation. Contrarily, there is a relatively large number of negative documents in the top of the result list, and it has been confirmed that negative feedback strategy is an important and useful way for adapting this scenario by several recent studies. In this paper, we consider a scenario when the search results are so poor that there are at most three relevant documents in the top twenty documents. Then, we conduct a novel study of multiple strategies for relevance feedback using both positive and negative examples from the first-pass retrieval to improve retrieval accuracy for such difficult queries. Experimental results on these TREC collections show that the proposed language model based multiple model feedback method which is generally more effective than both the baseline method and the methods using only positive or negative model.

  17. SoTRE's Speak Up: Students Share the Benefits of Teacher Researcher Experiences

    Science.gov (United States)

    Eubanks, E.; Allen, S.; Farmer, S.; Jones, K.

    2016-12-01

    Being Students of Teacher Researcher Experiences (SoTRE) gives students special advantages that most students do not get. Teachers Elizabeth Eubanks and Steve Allen share their knowledge gained via partnerships with Teacher Researcher Experiences (TRE's) such as the National Oceanographic and Atmospheric Administration Teacher at Sea program (NOAA- TAS), Polar TREC (Teachers and Researchers & Exploring & Collaboration), National Science Foundation (NSF) funded researchers, (EARTH) Education and Research: Testing Hypothesis, the RJ Dunlap Marine Conservation Program, C-DEBI (Center for Dark Energy Biosphere Investigations and (STARS) Sending Teachers Aboard Research Ships, The Maury Project and Mate. Students gain special privileges such as understanding unique research ideas, tracking tagged sharks, following daily journals written on location, taking part in cross-continental experiments, tracking real time data, exploring current research via posters or visiting universities. Furthermore, contacts made by a TRE give students an added set of resources. When doing experiments for class or advancing their education or career goals Eubanks and Allen help students connect with scientists. Many students have felt so strongly about the TRE relationship that they have presented at several local and international science conferences. Their message is to encourage scientists to partner with teachers. The benefits of participation in such conferences have included abstract writing and submission, travel, poster creation, oral presentation, networking and personal research presentation, all tools that they will carry with them for a lifetime.

  18. Cognitiva (TC de Beck en una muestra costarricense

    Directory of Open Access Journals (Sweden)

    Hannia Cabezas Pizarro

    2006-01-01

    Full Text Available En este estudio se explora una posible relación empírica entre la terapia racional emotivoconductual (TREC de Ellis y la terapia cognitiva (TC de Beck, dos de los modelos más conspicuos en el campo de la psicoterapia cognitiva actual. Si bien este modelo utiliza el término “cognitivo” en forma tal que se encuentra asociado con el afecto, la fisiología y la conducta (Dobson, 1986, sostiene que las perturbaciones emocionales, en esencia, son causadas por el proceso cognitivo del individuo. En esta investigación, se trabajó con una muestra de 200 estudiantes de la Universidad de Costa Rica de diferentes áreas a quienes se les aplicaron las escalas de: Attitudes and Beliefs Inventory (ABI [Escala de Actitudes y Creencias], y el Beck Depression Inventory, 2ª edición (BDI-II [Inventario de Depresión de Beck], escalas que fueron adaptadas al español. El análisis estadístico de los datos confirma empíricamente la relación entre ambos modelos.

  19. Augmenting performance feedback does not affect 4 km cycling time-trials in the heat.

    Science.gov (United States)

    Waldron, Mark; Villerius, Vincent; Murphy, Aron

    2015-01-01

    We compared the effects of (1) accurate and (2) surreptitiously augmented performance feedback on power output and physiological responses to a 4000 m time-trial in the heat. Nine cyclists completed a baseline (BaseL) 4000 m time-trial in ambient temperatures of 30°C, followed by two further 4000 m time-trials at the same temperature, randomly assigning the participants to an accurate (ACC; accurate feedback of baseline) or deceived (DEC; 2% increase above baseline) feedback group. The total power output (PO) and aerobic (Paer) and anaerobic (Pan) contributions were determined at 0.4 km stages during the time-trials, alongside measurements of rectal (Trec) and skin (Tskin) temperatures. There were no differences (P > 0.05) in any of the variables between BaseL, ACC and DEC, despite increases (P 0.05) between feedback condition and time-trial stage. Providing surreptitiously augmented performance feedback to well-trained cyclists did not alter their performance or physiological responses to a 4000 m time-trial in a hot environment. The assumed influence of augmented performance feedback was nullified in the heat, perhaps reflecting a central down-regulation of exercise intensity in response to an increased body temperature.

  20. PageRank without hyperlinks: Reranking with PubMed related article networks for biomedical text retrieval

    Directory of Open Access Journals (Sweden)

    Lin Jimmy

    2008-06-01

    Full Text Available Abstract Background Graph analysis algorithms such as PageRank and HITS have been successful in Web environments because they are able to extract important inter-document relationships from manually-created hyperlinks. We consider the application of these techniques to biomedical text retrieval. In the current PubMed® search interface, a MEDLINE® citation is connected to a number of related citations, which are in turn connected to other citations. Thus, a MEDLINE record represents a node in a vast content-similarity network. This article explores the hypothesis that these networks can be exploited for text retrieval, in the same manner as hyperlink graphs on the Web. Results We conducted a number of reranking experiments using the TREC 2005 genomics track test collection in which scores extracted from PageRank and HITS analysis were combined with scores returned by an off-the-shelf retrieval engine. Experiments demonstrate that incorporating PageRank scores yields significant improvements in terms of standard ranked-retrieval metrics. Conclusion The link structure of content-similarity networks can be exploited to improve the effectiveness of information retrieval systems. These results generalize the applicability of graph analysis algorithms to text retrieval in the biomedical domain.

  1. PageRank without hyperlinks: reranking with PubMed related article networks for biomedical text retrieval.

    Science.gov (United States)

    Lin, Jimmy

    2008-06-06

    Graph analysis algorithms such as PageRank and HITS have been successful in Web environments because they are able to extract important inter-document relationships from manually-created hyperlinks. We consider the application of these techniques to biomedical text retrieval. In the current PubMed(R) search interface, a MEDLINE(R) citation is connected to a number of related citations, which are in turn connected to other citations. Thus, a MEDLINE record represents a node in a vast content-similarity network. This article explores the hypothesis that these networks can be exploited for text retrieval, in the same manner as hyperlink graphs on the Web. We conducted a number of reranking experiments using the TREC 2005 genomics track test collection in which scores extracted from PageRank and HITS analysis were combined with scores returned by an off-the-shelf retrieval engine. Experiments demonstrate that incorporating PageRank scores yields significant improvements in terms of standard ranked-retrieval metrics. The link structure of content-similarity networks can be exploited to improve the effectiveness of information retrieval systems. These results generalize the applicability of graph analysis algorithms to text retrieval in the biomedical domain.

  2. Preparation of High Modulus Poly(Ethylene Terephthalate: Influence of Molecular Weight, Extrusion, and Drawing Parameters

    Directory of Open Access Journals (Sweden)

    Jian Min Zhang

    2017-01-01

    Full Text Available Poly(ethylene terephthalate (PET which is one of the most commercially important polymers, has for many years been an interesting candidate for the production of high performance fibres and tapes. In current study, we focus on investigating the effects of the various processing variables on the mechanical properties of PET produced by a distinctive process of melt spinning and uniaxial two-stage solid-state drawing (SSD. These processing variables include screw rotation speed during extrusion, fibre take-up speed, molecular weight, draw-ratio, and drawing temperature. As-spun PET production using a single-screw extrusion process was first optimized to induce an optimal polymer microstructure for subsequent drawing processes. It was found that less crystallization which occurred during this process would lead to better drawability, higher draw-ratio, and mechanical properties in the subsequent SSD process. Then the effect of drawing temperature (DT in uniaxial two-stage SSD process was studied to understand how DT (Trec would affect the crystallization, draw-ratio, and final mechanical properties of PET. The designed process in current work is simulated to an industrial production process for PET fibres; therefore, results and analysis in this paper have significant importance for industrial production.

  3. Biomarkers to assess potential developmental immunotoxicity in children

    International Nuclear Information System (INIS)

    Luster, Michael I.; Johnson, Victor J.; Yucesoy, Berran; Simeonova, Petia P.

    2005-01-01

    Clinical tests are readily available for assessing severe loss of immune function in children with diseases such as AIDS or primary immunodeficiency. However tests that could reliably identify subtle immune changes, as might be expected to result from exposure to developmental immunotoxic agents, are not readily available. A number of tests are described which we believe have potential applicability for epidemiological studies involving developmental immunotoxicity. Several of the tests, such as T cell receptor rearrangement excision circles (TRECs) and cytokine measurements, while highly relevant from a biological standpoint, may be precluded from use at the current time, for either technical issues or insufficient validation. Immunophenotyping and measurement of serum immunoglobulin levels, on the other hand, are well validated. Yet they may require extraordinary care in experimental design and technical performance in order to obtain data that would consistently detect subtle changes, as these tests are not generally considered highly sensitive. Quantification of the immune response to childhood vaccine, while up to the present used sparingly, may represent an excellent indicator for developmental immunotoxicity when conducted under appropriate conditions

  4. [Two families of X-linked lymphoproliferative disease type 1 characterized by agammaglobulinemia].

    Science.gov (United States)

    Li, W Y; Chen, J S; Zhao, Q; Dai, R X; Wang, Y P; Zhao, H Y; Chen, X M; Xue, X H; Sun, X Y; Tang, X M; Zhang, Y; Ding, Y; Zhao, X D; Zhang, Z Y

    2017-05-04

    Objective: To investigate the clinical and immunological laboratory features, mutations in SH2D1A gene and SAP protein expression in four children of two families with X-linked lymphoproliferative disease type 1(XLP-1). Method: Four patients (Family A including Patient 1 and Patient 2, Family B including Patient 3 and Patient 4) and their maternal relatives were enrolled in this study. The clinical manifestation, EBV infection status and chest CT scan were analyzed. The absolute and relative numbers of lymphocyte subsets, T lymphocyte proliferative response, SAP protein expression were assessed by flow cytometry. Quantification of signal joint TCR rearrangementexcision circle (sjTRECs), CDR3 spectratyping of TCRvβ and gene mutation of SH2D1A were detected by PCR based on genomic DNA or cDNA. Result: Four male patients from two families were diagnosed with XLP-1. The ages of disease onset were more than 1 year, more than 1 year, more than 1 month and 6 months. The ages at diagnosis were nine years and ten months, sixteen years and eight months, fourteen years and ten months, four years and nine months. All patients had recurrent infections and EBV infection. Patients 1, 2, and 3 had agammaglobulinemia and Patient 4 had hypogammaglobulinemia. Chest CT scan showed all patients had atelectasis and pneumonia, and Patient 3 had bronchiectasis. Patient 3 was diagnosised as Burkitt lymphoma. For immunological function, all patients exhibited reduced CD4/CD8 ratios, increased numbers of exhausted T lymphocyte, decreased number of NK cell. The numbers of total B lymphocyte and naïve B lymphocyte were normal, but the number of memory B lymphocyte declined in all cases. Four patients' copy numbers of sjTRECs were low and CDR3 spectratypings of TCRvβ showed mildly skewed. But their T lymphocyte proliferative response was normal. SAP protein expression in four cases were measured by flow cytometry. Two patients from Family A were absent and two patients from Family B showed

  5. Resultados da associação trabeculotomia-trabeculectomia em pacientes não idosos Results of trabeculotomy-trabeculectomy in not elderly patients

    Directory of Open Access Journals (Sweden)

    Angelo Ferreira Passos

    2009-08-01

    Full Text Available Objetivo: Avaliar os resultados da associação trabeculotomia-trabeculectomia (Tro-Trec em pacientes de 12 a 50 anos, com glaucoma moderado ou avançado. Métodos: estudo prospectivo de 19 olhos de 13 pacientes, de 12 a 50 anos (média de 33,77 ± 11,43, submetidos à Tro-Trec e seguidos por 21,6 ± 7,2 (5,1 a 29,7 meses. Resultados: A pressão intraocular, (PIO média inicial de 32,03 ± 10,01 mmHg (variando de 12 a 50, foi reduzida para 9,42 mmHg ± 3,50 (2 e 16, com redução da medicação tópica de 1,47 ± 1,54 (0 a 4 para 0,16 ± 0,37 (0 a 1 medicamentos. A PIO alvo foi atingida em 15 (78,94% olhos. Houve acentuada redução da PIO mesmo em olhos sem bolhas significativas. O procedimento resultou em hipotonia persistente em três olhos. Conclusão: A cirurgia proposta foi eficaz. A acentuada redução da PIO em olhos sem bolhas significativas sugere que, na faixa etária analisada, a trabeculotomia isolada pode ser suficiente para controle da PIO em alguns pacientes. A incidência de hipotonia foi significativa, porém não superior à relacionada à trabeculectomia isolada, para a mesma faixa etária.Purpose: To evaluate the results of the trabeculotomy-trabeculectomy combined procedure in 12 to 50 years old patients with moderate and advanced glaucoma. Methods: Nineteen eyes of thirteen patients underwent a trabeculotomy-trabeculectomy procedure and were prospectively analyzed and followed up for 21,6 ± 7,2 (5,1 a 29,7 months. Results: IOP was reduced from 32,03 ± 10,01 (12 to 50 mmHg to 9,42 ± 3,50 (2 e 16 mmHg with the number of topical medications being reduced from 1,47 ± 1,54 (0 a 4 to 0,16 ± 0,37 (0 a 1. The target IOP was obtained in 15 of the eyes (78,94%. A great IOP reduction was obtained in eyes without significant blebs. Three eyes developed persistent hipotony. Conclusion: The procedure proved to be effective. The IOP reduction in eyes without significant blebs make us to infer that isolated trabeculotomy should be

  6. Different profiles of immune reconstitution in children and adults with HIV-infection after highly active antiretroviral therapy

    Directory of Open Access Journals (Sweden)

    Leal Manuel

    2006-07-01

    Full Text Available Abstract Background Recent advances in characterizing the immune recovery of HIV-1-infected people have highlighted the importance of the thymus for peripheral T-cell diversity and function. The aim of this study was to investigate differences in immune reconstitution profiles after highly active antiretroviral therapy (HAART between HIV-children and adults. Methods HIV patients were grouped according to their previous clinical and immunological status: 9 HIV-Reconstituting-adults (HIV-Rec-adults and 10 HIV-Reconstituting-children (HIV-Rec-children on HAART with viral load (VL ≤400 copies/ml and CD4+ ≥500 cells/μL at least during 6 months before the study and CD4+ ≤300 cells/μL anytime before. Fifteen healthy-adults and 20 healthy-children (control subjects were used to calculate Z-score values to unify value scales between children and adults to make them comparable. Results HIV-Rec-children had higher T-cell receptor excision circles (TREC and lower interleukin (IL-7 levels than HIV-Rec-adults (p + (CD4+CD45RA hi+CD27+, naïve CD8+ (CD8+CD45RA hi+CD27+, and memory CD8+ (CD8+CD45RO+ cells/μl than HIV-Rec-adults, but similar memory CD4+ (CD4+CD45RO+ counts. HIV-Rec-children had lower naïve CD8+ Z-score values than HIV-Rec-adults (p = 0.05. Conclusion Our data suggest that HIV-Rec-children had better thymic function than HIV-Rec-adults and this fact affects the peripheral T-cell subsets. Thus, T-cell recovery after HAART in HIV-Rec-adults could be the consequence of antigen-independent peripheral T-cell expansion while in HIV-Rec-children thymic output could play a predominant role in immune reconstitution.

  7. Everybody Wins: How the IceCube Collaboration Capitalizes Teacher Deployments to the South Pole

    Science.gov (United States)

    Madsen, J.

    2017-12-01

    Over the last fifteen years, the IceCube Collaboration and its predecessor AMANDA have hosted eight teachers at South Pole with the ninth scheduled to deploy in the upcoming 2017-18 season. These deployments have been organized in conjunction with NSF funded programs that pair polar researchers with teachers. Teachers Experiencing the Arctic and Antarctica in the early years, and now PolarTREC, provide valuable structure, general training, build community among polar researchers and teachers, and archive resources developed by participants. The IceCube Collaboration has developed a successful team building approach for newly selected teachers that utilizes past polar teachers. For about a decade, we have provided a two week summer residential science course for a diverse group of ninth to twelve grade students in the University of Wisconsin-River Falls Upward Bound program. An authentic research experience is delivered by focusing on the process of science using a different accessible and meaningful project each year. For example, this summer students learned about design and construction by creating their own LED-embedded clothing. They programmed a microcontroller so the LEDs responded to an external input such as motion or sound. This panel presentation in the K-12 Education/Outreach: Effective Partnerships between Scientists and K-12 Teachers/Informal Educators including Authentic Student Research session will describe how this is a win for all involved. It gives the new teacher extensive opportunities to learn about living and working at the South Pole from past teachers, experience integrating into to an established team as they will do when they deploy, and lets them see creative ways to incorporate IceCube research into the classroom. It also provides a rich active learning experience for the UWRF Upward Bound students, and a way to keep engaged with teachers who have deployed in the past.

  8. Semantic concept-enriched dependence model for medical information retrieval.

    Science.gov (United States)

    Choi, Sungbin; Choi, Jinwook; Yoo, Sooyoung; Kim, Heechun; Lee, Youngho

    2014-02-01

    In medical information retrieval research, semantic resources have been mostly used by expanding the original query terms or estimating the concept importance weight. However, implicit term-dependency information contained in semantic concept terms has been overlooked or at least underused in most previous studies. In this study, we incorporate a semantic concept-based term-dependence feature into a formal retrieval model to improve its ranking performance. Standardized medical concept terms used by medical professionals were assumed to have implicit dependency within the same concept. We hypothesized that, by elaborately revising the ranking algorithms to favor documents that preserve those implicit dependencies, the ranking performance could be improved. The implicit dependence features are harvested from the original query using MetaMap. These semantic concept-based dependence features were incorporated into a semantic concept-enriched dependence model (SCDM). We designed four different variants of the model, with each variant having distinct characteristics in the feature formulation method. We performed leave-one-out cross validations on both a clinical document corpus (TREC Medical records track) and a medical literature corpus (OHSUMED), which are representative test collections in medical information retrieval research. Our semantic concept-enriched dependence model consistently outperformed other state-of-the-art retrieval methods. Analysis shows that the performance gain has occurred independently of the concept's explicit importance in the query. By capturing implicit knowledge with regard to the query term relationships and incorporating them into a ranking model, we could build a more robust and effective retrieval model, independent of the concept importance. Copyright © 2013 Elsevier Inc. All rights reserved.

  9. Sviluppi di Ricevitori E di Componentistica Per Banda 3 mm Ad INAF-OA Cagliari

    Science.gov (United States)

    Navarrini, Alessandro

    2017-11-01

    L'INAF-OA Cagliari (OACa) sta sviluppando un ricevitore criogenico a basso rumore basato su un mixer SSB (Single Side Band) a superconduttore SIS (Superconductor-Insulator-Superconductor) per la banda 3 mm. Il ricevitore, acquistato da IRAM, è stato fortemente modificato per essere adattato al fuoco Gregoriano di SRT (Sardinia Radio Telescope). Lo strumento è caratterizzato da una nuova criogenia a ciclo chiuso 4 K (per evitare l'uso di elio liquido in antenna), da un nuovo oscillatore locale (di tipo ALMA Banda 3) e da un nuovo sistema di controllo e di monitoraggio basato su schede Raspberry ed Arduino sviluppato ad OACa. Verranno presentati i recenti sviluppi sul ricevitore, inclusi i risultati preliminari della misura della temperatura di rumore, che raggiunge un valore pari a Trec=66 K alla frequenza di 86 GHz, nonostante la criogenia non sia ancora ottimizzata. L'INAF-OACa è coinvolto nel progetto AETHRA (Advanced European Technologies for Heterodyne Receivers for Astronomy) nel quadro del programma Radionet/Horizon2020 per il quale sta contribuendo al WP1 (Work Package 1). Lo scopo del WP1 è di sviluppare e costruire un dimostratore di un array di ricevitori a doppia polarizzazione per la banda 3 mm basato su amplificatori criogenici a basso rumore (LNA) in tecnologia a semiconduttore MMIC. Nell'ambito del WP1 l'OACa ha in carico il progetto di un OrthomodeTransducer (OMT) in guida d'onda o in tecnologia planare per la banda 72-116 GHz che sia integrabile con amplificatori MMICs ed adatto all'integrazione in un array da installare nel piano focale di un radiotelescopio. Verranno presentati i design preliminari degli OMT per AETHRA, che sono basati su prototipi sviluppati in passato da OACa.

  10. Automatic Decision Support for Clinical Diagnostic Literature Using Link Analysis in a Weighted Keyword Network.

    Science.gov (United States)

    Li, Shuqing; Sun, Ying; Soergel, Dagobert

    2017-12-23

    We present a novel approach to recommending articles from the medical literature that support clinical diagnostic decision-making, giving detailed descriptions of the associated ideas and principles. The specific goal is to retrieve biomedical articles that help answer questions of a specified type about a particular case. Based on the filtered keywords, MeSH(Medical Subject Headings) lexicon and the automatically extracted acronyms, the relationship between keywords and articles was built. The paper gives a detailed description of the process of by which keywords were measured and relevant articles identified based on link analysis in a weighted keywords network. Some important challenges identified in this study include the extraction of diagnosis-related keywords and a collection of valid sentences based on the keyword co-occurrence analysis and existing descriptions of symptoms. All data were taken from medical articles provided in the TREC (Text Retrieval Conference) clinical decision support track 2015. Ten standard topics and one demonstration topic were tested. In each case, a maximum of five articles with the highest relevance were returned. The total user satisfaction of 3.98 was 33% higher than average. The results also suggested that the smaller the number of results, the higher the average satisfaction. However, a few shortcomings were also revealed since medical literature recommendation for clinical diagnostic decision support is so complex a topic that it cannot be fully addressed through the semantic information carried solely by keywords in existing descriptions of symptoms. Nevertheless, the fact that these articles are actually relevant will no doubt inspire future research.

  11. Oral supplementation with Lactobacillus delbrueckii subsp. bulgaricus 8481 enhances systemic immunity in elderly subjects.

    Science.gov (United States)

    Moro-García, Marco Antonio; Alonso-Arias, Rebeca; Baltadjieva, Maria; Fernández Benítez, Carlos; Fernández Barrial, Manuel Amadeo; Díaz Ruisánchez, Enrique; Alonso Santos, Ricardo; Alvarez Sánchez, Magdalena; Saavedra Miján, Juan; López-Larrea, Carlos

    2013-08-01

    Throughout life, there is an aging of the immune system that causes impairment of its defense capability. Prevention or delay of this deterioration is considered crucial to maintain general health and increase longevity. We evaluated whether dietary supplementation with Lactobacillus delbrueckii subsp. bulgaricus 8481 could enhance the immune response in the elderly. This multi-center, double-blind, and placebo controlled study enrolled 61 elderly volunteers who were randomly assigned to receive either placebo or probiotics. Each capsule of probiotics contained at least 3 × 10(7)  L. delbrueckii subsp. bulgaricus 8481. Individuals in the study were administered three capsules per day for 6 months. Blood samples were obtained at baseline (time 0), end of month 3, and month 6. We characterized cell subpopulations, measured cytokines by flow cytometry, quantified T cell receptor excision circle (TREC) by real-time PCR (RT-PCR), and determined human β-defensin-2 (hBD-2) concentrations and human cytomegalovirus (CMV) titers by enzyme-linked immunosorbent assay (ELISA). Elderly responded to the intake of probiotic with an increase in the percentage of NK cells, an improvement in the parameters defining the immune risk profile (IRP), and an increase in the T cell subsets that are less differentiated. The probiotic group also showed decreased concentrations of the pro-inflammatory cytokine IL-8 but increased antimicrobial peptide hBD-2. These effects disappeared within 6 months of stopping the probiotic intake. Immunomodulation induced by L. delbrueckii subsp. bulgaricus 8481 could favor the maintenance of an adequate immune response, mainly by slowing the aging of the T cell subpopulations and increasing the number of immature T cells which are potential responders to new antigens.

  12. Energy scaling of the "heartbeat" pulse width of GRS 1915+105, IGR J17091-3624, and MXB 1730-335 from Rossi-XTE observations

    Science.gov (United States)

    Maselli, A.; Capitanio, F.; Feroci, M.; Massa, F.; Massaro, E.; Mineo, T.

    2018-04-01

    We investigate some key aspects of the "heartbeat" variability consisting of series of bursts with a slow rise and a fast decay, thus far detected only in GRS 1915+105, IGR J17091-3624, and MXB 1730-335. A previous analysis based on BeppoSAX data of GRS 1915+105 revealed a hard-X delay (HXD), that is a lag of the burst rise at higher energies with respect to lower ones; this leads to narrower pulse widths, w, at higher energies. We here use some light curves of Rossi-XTE observations of GRS 1915+105 for a deeper analysis of this effect and search for its presence in those extracted from some IGR J17091-3624 and MXB 1730-335 observations performed with the same satellite. Our results show that, at variance with GRS 1915+105, no HXD is evident in the light curves of MXB 1730-335 and only a marginal HXD may be argued for IGR J17091-3624. For GRS 1915+105 we find a decreasing trend of the pulse width with energy following a power law w = A ṡ E-s with an index s ≈ 0.8. Furthermore, we confirm the increase of the HXD with the recurrence time Trec of the bursts in each series that was already found in previous works using BeppoSAX data. Based on a spectral analysis of these three sources we conclude that the differences highlighted in the properties of the "heartbeat" variability are probably related to the different accreting compact object and the eventual presence of a corona in these binary interacting systems.

  13. THE MINERALOGY AND STRUCTURE OF THE INNER DEBRIS DISK OF β PICTORIS

    International Nuclear Information System (INIS)

    Li Dan; Telesco, Charles M.; Wright, Christopher M.

    2012-01-01

    We observed the edge-on, planet-bearing disk of β Pictoris using T-ReCS at Gemini to clarify and extend previous observations and conclusions about this unique system. Our spectroscopy and spectral modeling of the 10 μm silicate feature constrain the spatial distributions of three representative dust components (0.1 μm/2.0 μm glassy olivine and crystalline forsterite) across the inner 20 AU of the disk. We confirm that the 2.0 μm glassy olivine is strongly peaked in the disk center and that the 0.1 μm glassy olivine does not show this concentration, but rather is double peaked, with the peaks on either side of the star. However, we do not see the strong difference in brightness between those two peaks reported in a previous study. Although the spatial distribution of the 0.1 μm dust is consistent with the scenario of a dust-replenishing planetesimal belt embedded in the disk, we note an alternative interpretation that can explain the spatial distributions of the 0.1 μm and 2.0 μm grains simultaneously and does not require the planetesimal belt. In addition to the spectroscopy, we also obtained a new 11.7 μm image of the β Pic disk. By comparing this image with that acquired in 2003, we confirm the existence and overall shape of the dusty clump at 52 AU in the SW disk. We speculate that the clump's projected spatial displacement of ∼2.0 AU, a 3.6σ result, between two epochs separated by seven years is due to the Keplerian motion of the clump at an orbital radius of 54.3 +2.0 –1.2 AU.

  14. MeSH: a window into full text for document summarization.

    Science.gov (United States)

    Bhattacharya, Sanmitra; Ha-Thuc, Viet; Srinivasan, Padmini

    2011-07-01

    Previous research in the biomedical text-mining domain has historically been limited to titles, abstracts and metadata available in MEDLINE records. Recent research initiatives such as TREC Genomics and BioCreAtIvE strongly point to the merits of moving beyond abstracts and into the realm of full texts. Full texts are, however, more expensive to process not only in terms of resources needed but also in terms of accuracy. Since full texts contain embellishments that elaborate, contextualize, contrast, supplement, etc., there is greater risk for false positives. Motivated by this, we explore an approach that offers a compromise between the extremes of abstracts and full texts. Specifically, we create reduced versions of full text documents that contain only important portions. In the long-term, our goal is to explore the use of such summaries for functions such as document retrieval and information extraction. Here, we focus on designing summarization strategies. In particular, we explore the use of MeSH terms, manually assigned to documents by trained annotators, as clues to select important text segments from the full text documents. Our experiments confirm the ability of our approach to pick the important text portions. Using the ROUGE measures for evaluation, we were able to achieve maximum ROUGE-1, ROUGE-2 and ROUGE-SU4 F-scores of 0.4150, 0.1435 and 0.1782, respectively, for our MeSH term-based method versus the maximum baseline scores of 0.3815, 0.1353 and 0.1428, respectively. Using a MeSH profile-based strategy, we were able to achieve maximum ROUGE F-scores of 0.4320, 0.1497 and 0.1887, respectively. Human evaluation of the baselines and our proposed strategies further corroborates the ability of our method to select important sentences from the full texts. sanmitra-bhattacharya@uiowa.edu; padmini-srinivasan@uiowa.edu.

  15. Multilevel predictors of adolescent physical activity: a longitudinal analysis

    Directory of Open Access Journals (Sweden)

    Hearst Mary O

    2012-02-01

    Full Text Available Abstract Background To examine how factors from a social ecologic model predict physical activity (PA among adolescents using a longitudinal analysis. Methods Participants in this longitudinal study were adolescents (ages 10-16 at baseline and one parent enrolled in the Transdisciplinary Research on Energetics and Cancer-Identifying Determinants of Eating and Activity (TREC-IDEA and the Etiology of Childhood Obesity (ECHO. Both studies were designed to assess a socio-ecologic model of adolescent obesity risk. PA was collected using ActiGraph activity monitors at two time points 24 months apart. Other measures included objective height and weight, adolescent and parent questionnaires on multilevel psychological, behavioral and social determinants of PA, and a home PA equipment inventory. Analysis was conducted using SAS, including descriptive characteristics, bivariate and stepped multivariate mixed models, using baseline adjustment. Models were stratified by gender. Results There were 578 adolescents with complete data. Results suggest few statistically significant longitudinal associations with physical activity measured as minutes of MVPA or total counts from accelerometers. For boys, greater self-efficacy (B = 0.75, p = 0.01 and baseline MVPA (B = 0.55, p p = 0.01 and barriers (B = -0.32, p = 0.05 significantly predicted MVPA at follow-up in the full model. The full multilevel model explained 30% of the variance in PA among boys and 24% among girls. Conclusions PA change in adolescents is a complex issue that is not easily understood. Our findings suggest early PA habits are the most important predictor of PA levels in adolescence. Intervention may be necessary prior to middle school to maintain PA through adolescence.

  16. Connecting polar research to NGSS STEM classroom lessons

    Science.gov (United States)

    Brinker, R.; Kast, D.

    2016-12-01

    Next Generation Science Standards (NGSS) are designed to bring consistent, rigorous science teaching across the United States. Topics are categorized as Performance Expectations (PE), Disciplinary Core Ideas (DCI), Cross-Cutting Concepts (CCC), and Science and Engineering Practices (SEP). NGSS includes a focus on environmental science and climate change across grade levels. Earth and planetary sciences are required at the high school level. Integrating polar science lessons into NGSS classrooms brings relevant, rigorous climate change curriculum across grade levels. Polar science provides opportunities for students to use current data during lessons, conduct their own field work, and collaborate with scientists. Polar science provides a framework of learning that is novel to most students. Inquiry and engagement are high with polar science lessons. Phenomenon related to polar science provide an excellent tool for science teachers to use to engage students in a lesson, stimulate inquiry, and promote critical thinking. When taught effectively, students see the connections between their community, polar regions and climate change, regardless of where on the planet students live. This presentation describes examples of how to effectively implement NGSS lessons by incorporating polar science lessons and field research. Examples of introductory phenomenon and aligned PEs, CCCs, DCIs, and SEPs are given. Suggested student activities, assessments, examples of student work, student research, labs, and PolarTREC fieldwork, use of current science data, and connections to scientists in the field are provided. The goals of the presentation are to give teachers a blueprint to follow when implementing NGSS lessons, and give scientists an understanding of the basics of NGSS so they may be better able to relate their work to U.S. science education and be more effective communicators of their science findings.

  17. Persistent low thymic activity and non-cardiac mortality in children with chromosome 22q11.2 microdeletion and partial DiGeorge syndrome.

    Science.gov (United States)

    Eberle, P; Berger, C; Junge, S; Dougoud, S; Büchel, E Valsangiacomo; Riegel, M; Schinzel, A; Seger, R; Güngör, T

    2009-02-01

    A subgroup of patients with 22q11.2 microdeletion and partial DiGeorge syndrome (pDGS) appears to be susceptible to non-cardiac mortality (NCM) despite sufficient overall CD4(+) T cells. To detect these patients, 20 newborns with 22q11.2 microdeletion and congenital heart disease were followed prospectively for 6 years. Besides detailed clinical assessment, longitudinal monitoring of naive CD4(+) and cytotoxic CD3(+)CD8(+) T cells (CTL) was performed. To monitor thymic activity, we analysed naive platelet endothelial cell adhesion molecule-1 (CD31(+)) expressing CD45RA(+)RO(-)CD4(+) cells containing high numbers of T cell receptor excision circle (T(REC))-bearing lymphocytes and compared them with normal values of healthy children (n = 75). Comparing two age periods, low overall CD4(+) and naive CD4(+) T cell numbers were observed in 65%/75%, respectively, of patients in period A ( 1/< 7 years). The percentage of patients with low CTLs (< P10) remained robust until school age (period A: 60%; period B: 50%). Low numbers of CTLs were associated with abnormally low naive CD45RA(+)RO(-)CD4(+) T cells. A high-risk (HR) group (n = 11) and a standard-risk (SR) (n = 9) group were identified. HR patients were characterized by low numbers of both naive CD4(+) and CTLs and were prone to lethal infectious and lymphoproliferative complications (NCM: four of 11; cardiac mortality: one of 11) while SR patients were not (NCM: none of nine; cardiac mortality: two of nine). Naive CD31(+)CD45RA(+)RO(-)CD4(+), naive CD45RA(+)RO(-)CD4(+) T cells as well as T(RECs)/10(6) mononuclear cells were abnormally low in HR and normal in SR patients. Longitudinal monitoring of naive CD4(+) and cytotoxic T cells may help to discriminate pDGS patients at increased risk for NCM.

  18. A COMPREHENSIVE DUST MODEL APPLIED TO THE RESOLVED BETA PICTORIS DEBRIS DISK FROM OPTICAL TO RADIO WAVELENGTHS

    Energy Technology Data Exchange (ETDEWEB)

    Ballering, Nicholas P.; Su, Kate Y. L.; Rieke, George H.; Gáspár, András, E-mail: ballerin@email.arizona.edu [Steward Observatory, University of Arizona, 933 North Cherry Avenue, Tucson, AZ 85721 (United States)

    2016-06-01

    We investigate whether varying the dust composition (described by the optical constants) can solve a persistent problem in debris disk modeling—the inability to fit the thermal emission without overpredicting the scattered light. We model five images of the β Pictoris disk: two in scattered light from the Hubble Space Telescope ( HST )/Space Telescope Imaging Spectrograph at 0.58 μ m and HST /Wide Field Camera 3 (WFC 3) at 1.16 μ m, and three in thermal emission from Spitzer /Multiband Imaging Photometer for Spitzer (MIPS) at 24 μ m, Herschel /PACS at 70 μ m, and Atacama Large Millimeter/submillimeter Array at 870 μ m. The WFC3 and MIPS data are published here for the first time. We focus our modeling on the outer part of this disk, consisting of a parent body ring and a halo of small grains. First, we confirm that a model using astronomical silicates cannot simultaneously fit the thermal and scattered light data. Next, we use a simple generic function for the optical constants to show that varying the dust composition can improve the fit substantially. Finally, we model the dust as a mixture of the most plausible debris constituents: astronomical silicates, water ice, organic refractory material, and vacuum. We achieve a good fit to all data sets with grains composed predominantly of silicates and organics, while ice and vacuum are, at most, present in small amounts. This composition is similar to one derived from previous work on the HR 4796A disk. Our model also fits the thermal spectral energy distribution, scattered light colors, and high-resolution mid-IR data from T-ReCS for this disk. Additionally, we show that sub-blowout grains are a necessary component of the halo.

  19. Multi-dimensional classification of biomedical text: toward automated, practical provision of high-utility text to diverse users.

    Science.gov (United States)

    Shatkay, Hagit; Pan, Fengxia; Rzhetsky, Andrey; Wilbur, W John

    2008-09-15

    Much current research in biomedical text mining is concerned with serving biologists by extracting certain information from scientific text. We note that there is no 'average biologist' client; different users have distinct needs. For instance, as noted in past evaluation efforts (BioCreative, TREC, KDD) database curators are often interested in sentences showing experimental evidence and methods. Conversely, lab scientists searching for known information about a protein may seek facts, typically stated with high confidence. Text-mining systems can target specific end-users and become more effective, if the system can first identify text regions rich in the type of scientific content that is of interest to the user, retrieve documents that have many such regions, and focus on fact extraction from these regions. Here, we study the ability to characterize and classify such text automatically. We have recently introduced a multi-dimensional categorization and annotation scheme, developed to be applicable to a wide variety of biomedical documents and scientific statements, while intended to support specific biomedical retrieval and extraction tasks. The annotation scheme was applied to a large corpus in a controlled effort by eight independent annotators, where three individual annotators independently tagged each sentence. We then trained and tested machine learning classifiers to automatically categorize sentence fragments based on the annotation. We discuss here the issues involved in this task, and present an overview of the results. The latter strongly suggest that automatic annotation along most of the dimensions is highly feasible, and that this new framework for scientific sentence categorization is applicable in practice.

  20. Optimisation and validation of a remote monitoring system (Onco-TreC) for home-based management of oral anticancer therapies: an Italian multicentre feasibility study.

    Science.gov (United States)

    Passardi, Alessandro; Rizzo, Mimma; Maines, Francesca; Tondini, Carlo; Zambelli, Alberto; Vespignani, Roberto; Andreis, Daniele; Massa, Ilaria; Dianti, Marco; Forti, Stefano; Piras, Enrico Maria; Eccher, Claudio

    2017-05-29

    Despite the growing number of oral agents available for cancer treatment, their efficacy may be reduced due to the lack of adherence, inappropriate adverse event self-management and arbitrary dose adjustment. The management of anticancer therapies could exponentially benefit from the introduction of mobile health technologies in a highly integrated electronic oncology system. We plan to customise and fine-tune an existing monitoring TreC platform used in different chronic diseases in the oncology setting. This project follows a multistep approach with two major purposes: 1. participatory design techniques driven by Health Literacy and Patient Reported Outcomes principles in order to adapt the system to the oncology setting involving patients and healthcare providers; 2. a prospective training-validation, interventional, non-pharmacological, multicentre study on a series of consecutive patients with cancer (20 and 60 patients in the training and validation steps, respectively) in order to assess system capability, usability and acceptability. The novel Onco-TreC 2.0 is expected to contribute to improving the adherence and safety of cancer care, promoting patient empowerment and patient-doctor communication. Ethical approval was obtained from the Independent Ethics Committees of the participating institutions (CEIIAV protocol Number 2549/2015; reference Number 1315-PU). Informed consent will be obtained from all study participants. Findings will be disseminated through peer-reviewed journals, conferences and event presentations. ClinicalTrials.gov (NCT02921724); (Pre-results). Other study ID Number: IRST100.18. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  1. IceBridge: Bringing a Field Campaign Home

    Science.gov (United States)

    Woods, J.; Beck, J.; Bartholow, S.

    2015-12-01

    IceBridge, a six-year NASA mission, is the largest airborne survey of Earth's polar ice ever flown. It will yield an unprecedented three-dimensional view of Arctic and Antarctic ice sheets, ice shelves and sea ice. These flights will provide a yearly, multi-instrument look at the behavior of the rapidly changing features of the Greenland and Antarctic ice. Data collected during IceBridge will help scientists bridge the gap in polar observations between NASA's Ice, Cloud and Land Elevation Satellite (ICESat) -- in orbit since 2003 -- and ICESat-2, planned for 2017. ICESat stopped collecting science data in 2009, making IceBridge critical for ensuring a continuous series of observations. IceBridge will use airborne instruments to map Arctic and Antarctic areas once a year at a minimum, with new campaigns being developed during the Arctic melt season. IceBridge flights are conducted in the spring and summer for the Arctic and in the fall over Antarctica. Other smaller airborne surveys around the world are also part of the IceBridge campaign. IceBridge actively engages the public and educators through a variety of outlets ranging from communications strategies through social media outlets, to larger organized efforts such as PolarTREC. In field activities include blog posts, photo updates, in flight chat sessions, and more intensive live events to include google hangouts, where field team members can interact with the public during a scheduled broadcast. The IceBridge team provides scientists and other team members with the training and support to become communicators in their own right. There is an exciting new initiative where IceBridge will be collaborating with Undergraduate and Graduate students to integrate the next generation of scientists and communicators into the Science Teams. This will be explored through partnerships with institutions that are interested in mentoring through project based initiatives.

  2. Deficient innate immunity, thymopoiesis, and gene expression response to radiation in survivors of childhood acute lymphoblastic leukemia.

    Science.gov (United States)

    Leung, Wing; Neale, Geoffrey; Behm, Fred; Iyengar, Rekha; Finkelstein, David; Kastan, Michael B; Pui, Ching-Hon

    2010-06-01

    Survivors of childhood acute lymphoblastic leukemia (ALL) are at an increased risk of developing secondary malignant neoplasms. Radiation and chemotherapy can cause mutations and cytogenetic abnormalities and induce genomic instability. Host immunity and appropriate DNA damage responses are critical inhibitors of carcinogenesis. Therefore, we sought to determine the long-term effects of ALL treatment on immune function and response to DNA damage. Comparative studies on 14 survivors in first complete remission and 16 siblings were conducted. In comparison to siblings on the cells that were involved in adaptive immunity, the patients had either higher numbers (CD19+ B cells and CD4+CD25+ T regulatory cells) or similar numbers (alphabetaT cells and CD45RO+/RA- memory T cells) in the blood. In contrast, patients had lower numbers of all lymphocyte subsets involved in innate immunity (gammadeltaT cells and all NK subsets, including KIR2DL1+ cells, KIR2DL2/L3+ cells, and CD16+ cells), and lower natural cytotoxicity against K562 leukemia cells. Thymopoiesis was lower in patients, as demonstrated by less CD45RO-/RA+ naïve T cell and less SjTREC levels in the blood, whereas the Vbeta spectratype complexity score was similar. Array of gene expression response to low-dose radiation showed that about 70% of the probesets had a reduced response in patients. One of these genes, SCHIP-1, was also among the top-ranked single nucleotide polymorphisms (SNPs) during the whole-genome scanning by SNP microarray analysis. ALL survivors were deficient in innate immunity, thymopoiesis, and DNA damage responses to radiation. These defects may contribute to their increased likelihood of second malignancy. Copyright (c) 2010 Elsevier Ltd. All rights reserved.

  3. Screening for antimicrobial activity of ten medicinal plants used in Colombian folkloric medicine: A possible alternative in the treatment of non-nosocomial infections

    Directory of Open Access Journals (Sweden)

    Ocampo Saul A

    2006-02-01

    Full Text Available Abstract Background The antimicrobial activity and Minimal Inhibitory Concentration (MIC of the extracts of Bidens pilosa L., Bixa orellana L., Cecropia peltata L., Cinchona officinalis L., Gliricidia sepium H.B. & K, Jacaranda mimosifolia D.Don, Justicia secunda Vahl., Piper pulchrum C.DC, P. paniculata L. and Spilanthes americana Hieron were evaluated against five bacteria (Staphylococcus aureus, Streptococcus β hemolític, Bacillus cereus, Pseudomonas aeruginosa, and Escherichia coli, and one yeast (Candida albicans. These plants are used in Colombian folk medicine to treat infections of microbial origin. Methods Plants were collected by farmers and traditional healers. The ethanol, hexane and water extracts were obtained by standard methods. The antimicrobial activity was found by using a modified agar well diffusion method. All microorganisms were obtained from the American Type Culture Collection (ATCC. MIC was determined in the plant extracts that showed some efficacy against the tested microorganisms. Gentamycin sulfate (1.0 μg/ml, clindamycin (0.3 μg/ml and nystatin (1.0 μg/ml were used as positive controls. Results The water extracts of Bidens pilosa L., Jacaranda mimosifolia D.Don, and Piper pulchrum C.DC showed a higher activity against Bacillus cereus and Escherichia coli than gentamycin sulfate. Similarly, the ethanol extracts of all species were active against Staphylococcus aureus except for Justicia secunda. Furthermore, Bixa orellana L, Justicia secunda Vahl. and Piper pulchrum C.DC presented the lowest MICs against Escherichia coli (0.8, 0.6 and 0.6 μg/ml, respectively compared to gentamycin sulfate (0.9 8g/ml. Likewise, Justicia secunda and Piper pulchrum C.DC showed an analogous MIC against Candida albicans (0.5 and 0.6 μg/ml, respectively compared to nystatin (0.6 μg/ml. Bixa orellana L, exhibited a better MIC against Bacillus cereus (0.2 μg/ml than gentamycin sulfate (0.5 μg/ml. Conclusion This in vitro study

  4. Florística e estrutura da comunidade arbórea de uma floresta estacional semidecidual secundária em Viçosa, MG

    Directory of Open Access Journals (Sweden)

    Antonio Jorge Tourinho Braga

    2011-06-01

    Full Text Available Este trabalho teve como objetivo estudar a composição florística e a estrutura da comunidade arbórea, bem como a distribuição das espécies em diferentes grupos ecológicos e os solos dos estádios inicial e avançado, de uma Floresta Estacional Semidecidual localizada no campus da Universidade Federal de Viçosa, em Viçosa, MG (20°46' S e 42°52' W. O levantamento foi realizado em meio hectare, onde foram alocadas 10 parcelas de 25 x 10 m em cada trecho, sendo amostrados todos os indivíduos com circunferência do tronco a 1,30 m do solo (CAP > 15 cm. Registraram-se 820 indivíduos, sendo 440 no trecho de floresta inicial e 380 no de floresta avançada. No levantamento florístico da floresta inicial foram amostradas 76 espécies, pertencentes a 28 famílias, destacando-se como as de maior número de indivíduos Fabaceae (137, Urticaceae (45 e Sapindaceae (41 e, as com os maiores valores de importância, Cecropia glaziovii Snethl., Anadenanthera peregrina (L. Speng., Piptadenia gonoacantha (Mart. Macbr., Allophylus sericeus Radlk., Siparuna guianensis Aubl. e Maclura tinctoria (L. Don ex Steud. O índice de diversidade de Shannon (H' foi de 3,57 nat.ind.-1 e a equabilidade (J', de 0,82. Já na floresta avançada foram amostradas 59 espécies, distribuídas em 26 famílias, das quais Fabaceae (103, Meliaceae (49 e Flacourtiaceae (34 sobressaíram com maior número de indivíduos. Por sua vez, as espécies com os maiores valores de importância foram A. peregrina, Trichilia pallida Swartz, Cariniana estrellensis (Raddi Kuntze., P. gonoacantha, Rollinia silvatica Mart. e S. guianensi. O índice de diversidade de Shannon (H' foi de 3,49 nat.ind.-1 e a equabilidade (J', de 0,85. No contínuo, o índice de Shannon (H' e a equabilidade (J' foram de 3,82 nat.ind.-1 e 0,84, respectivamente. Cada floresta apresentou distinta identidade florística e estrutural, tendendo a ser minimizada com o avanço da sucessão.

  5. Comparando técnicas de nucleação utilizadas na restauração de áreas degradadas na Amazônia brasileira

    Directory of Open Access Journals (Sweden)

    Niwton Leal Filho

    2013-08-01

    Full Text Available A exploração de petróleo na Amazônia, em geral, implica na abertura de clareiras. No plantio tradicional de mudas de espécies arbóreas nessas áreas remotas degradadas, usam-se os transportes aéreo e fluvial de máquinas e insumos, o que encarece o processo de restauração. Objetivando o desenvolvimento de técnicas de nucleação de baixo custo baseadas na aplicação de elementos naturais disponíveis localmente, o que permite a regeneração natural de espécies pioneiras arbóreas, na região de Urucu, AM, foram testados cinco tratamentos com cinco repetições, distribuídos em quadrado latino de 25 x 25 m: T0 (controle, T1 (aplicação de "topsoil" sobre canteiros de solo escarificado manualmente, adubado e com laterais protegidas por troncos de Cecropia spp., T2 (aplicação de "topsoil" sobre canteiros adubados e sem proteção lateral, T3 (aplicação de "topsoil" diretamente sobre a superfície adubada da área degradada e T4 (aplicação de "topsoil" por hidrossemeadura sobre canteiros. Foram avaliados os efeitos sobre a densidade aparente e a fertilidade do solo e a densidade de plântulas emergidas e seu crescimento. Após 18 meses, os tratamentos T1, T2 e T3 apresentaram, respectivamente, o estabelecimento de 3, 1, 1 ind. m-2, com altura similar, provenientes do "topsoil". Os tratamentos T0 e T4 não apresentaram emergência de plântulas. A densidade do solo foi mais elevada nos tratamentos (>1,3 g cm-3 que na floresta (0,95 cm-3, enquanto a aplicação de fertilizante e calcário promoveu aumento na fertilidade do solo nos tratamentos, exceto de N e matéria orgânica, com teores mais elevados na floresta.

  6. The soil-plant relationship of nitrogen use in three tropical tree species

    Directory of Open Access Journals (Sweden)

    E. F. L. Pereira-Silva

    2012-10-01

    Full Text Available We characterized and compared the use of nitrate (N-NO3, in three recognized pioneer and secondary tropical species, analyzing their relationships with the availability of inorganic nitrogen in the soil of a riparian forest. We tested the hypothesis that pioneer species of the ecological succession (Cecropia glaziovi – Cgl would be more responsive to N-NO3 available and would have high nitrate reductase activity (NRA in leaves while secondary species (Inga marginata – Ima and Hymenaea courbaril – Hco would have less responsiveness and would have lower levels of this enzyme on its leaves. We evaluated, tested and compared the NRA and N-NO3 content in leaves and xylem sap of each species. We measured N-NO3 and N-NH4+ content in the soil. The results for Cgl showed an N-NO3 content of xylem sap that met the demand of NRA and were correlated with inorganic soil nitrogen, showing the responsiveness of species to N-NO3. Hco was verified as less responsive to assimilation and high N-NO3 content in leaves. The species Ima showed an intermediate behaviour, which suggests the possibility of use of other nitrogen forms. The ecophysiological behaviours of the plants were related to the seasonal variation and indicate that these plants use strategies with different responsiveness to the use of soil N-NO3. In this sense and considering that these species are typically used in ecological restoration projects in Brazil, the knowledge of a strategy for nitrogen use specific to each of them can assist in choosing the species appropriate to the edaphic conditions of the environment.

  7. Fatores edáficos e as variações florísticas de um trecho de Mata Ciliar do Rio Gualaxo do Norte, Mariana, MG

    Directory of Open Access Journals (Sweden)

    Iolanda de Sena Gonçalves

    2011-12-01

    Full Text Available Este trabalho teve como objetivo verificar a correlação entre a distribuição de espécies arbóreas ciliares do rio Gualaxo do Norte (S20°16'31,9" W43°26'15,3" e S20°16'30,6" W43°26'07,3" com fatores edáficos, assim como se existem espécies de ocorrência restrita à área de depleção ciliar que possam ser indicadas para recuperação de matas ciliares. As parcelas foram alocadas em 1 ha dividido em três blocos com declividades distintas. Todos os indivíduos com circunferência do tronco a 1,30 m do solo igual ou superior a 15 cm foram registrados e identificados. Foram coletadas cinco amostras simples de solo em cada parcela para análises químicas de fertilidade. A ordenação dos dados de solo e vegetação foi realizada pela análise de correspondência canônica (CCA, que indicou que variações na fertilidade, na acidez do solo e na altitude estavam influenciando a distribuição da vegetação arbórea ao longo do gradiente topográfico. Albizia hassleri, Bathysa meridionalis, Cariniana estrelensis, Casearia gossypiosperma, Casearia sp., Cecropia hololeuca, Himatanthus lancifolius, Luehea grandiflora, Picramnia sp., Platypodium elegans, Pseudopiptadenia contorta, Tibouchina candoleana e Virola oleifera são espécies adaptadas a condições edáficas com elevada acidez e fertilidade muito baixa, apresentando potencial para utilização em projetos de recuperação de áreas degradadas, principalmente de encostas e topo de morros. Já Casearia sylvestris, Dalbergia villosa, Dendropanax cuneatus, Machaerium aculeatum, Machaerium stiptatum, Ocotea odorifera, Ocotea pulchella, Rollinea longifolia, Schinus terebinthifolius, Tibouchina granulosa, Vernonia piptocarphoides e Vismia sp. estavam correlacionadas com solos menos ácidos, mais férteis e mais próximos ao rio, apresentando potencial para a restauração florestal em áreas ciliares.

  8. Measurements of biogenic hydrocarbons and carbonyl compounds emitted by trees from temperate warm Atlantic rainforest, Brazil.

    Science.gov (United States)

    Carvalho, Lilian R F; Vasconcellos, Perola C; Mantovani, Waldir; Pool, Cristina S; Pisani, Silvana O

    2005-05-01

    This study is part of a three-year project on biogenic volatile organic compound (VOC) emissions from trees of the temperate warm Atlantic rainforest found in the metropolitan area of Sao Paulo City (MASP). No study of VOC emission rates from plant species has been carried out in the temperate warm Atlantic rainforest of Brazil prior to this work. Eleven species were selected (Alchornea sidifolia, Cupania oblongifolia, Cecropia pachystachia, Syagrus romanzoffiana, Casearia sylvestris, Machaerium villosum, Trema micrantha, Croton floribundus, Myrcia rostrata, Solanum erianthum and Ficus insipida) and some of them were studied in urban, sub-urban and forest areas inside the MASP in order to evaluate biogenic VOC composition at sites characterized by different emission sources. Biogenic VOC emissions were determined by placing branches of plants in a dynamic enclosure system, an all-Teflon cuvette, and by sampling the compounds in the air leaving the cuvette. Pre-concentration using adsorbents to retain the VOC, followed by GC-MS after thermal desorption of the sample, was employed to determine the amount of biogenic hydrocarbons. The collection of carbonyl compounds on a 2,4-dinitrophenylhydrazine coated silica followed by HPLC-UV was used to analyze low molecular weight carbonyl compounds. Emission rates of isoprene, alpha-pinene, camphene and limonene ranged from 0.01 to 2.16 microg C h(-1) g(-1) and emission rates of aldehydes (C(2)-C(6)), acrolein, methacrolein and 2-butanone ranged from 1.5 x 10(-2) to 2.3 micro g C h(-1) g (-1). Ambient and leaf temperatures, relative humidity, light intensity, O(3) and NO(x) levels in the local atmosphere were monitored during experiments. It was possible to identify different biogenic VOCs emitted from typical plants of temperate warm Atlantic rainforest. The emission rates were reported as a function of the type of site investigated and were only provided for compounds for which quantification was feasible. Other biogenic

  9. Mid-Holocene to Present Climate Transition in Tropical South America

    Science.gov (United States)

    Turcq, B.; Cordeiro, R.; Sifeddine, A.; Braconnot, P.; Dias, P. S.; Costa, R.; Jorgetti, T.

    2008-12-01

    The classical illustration of Holocene climate changes in tropical South America is the huge rising of Titicaca lake level from 4400 to 4000 cal BP. Because the Amazon basin is the source of Andean rainfalls we have explored Amazonian data of climate changes during the Holocene to better understand the cause of this abrupt transition. Amazonian data confirm the existence of mid-Holocene dryness: (1) lacustrine level studies show a lower precipitation/evaporation budget than present, with the lowest lake levels between 8500 and 6800 cal BP; (2) although the dominant Holocene vegetation has always been the rainforest in the heart of Amazonia, this forest expanded towards the northwestern and southwestern regions from 6800 to 1550 cal BP, moreover, pioneer elements of the rainforest developed during the mid-Holocene and the best example is those of Cecropia, between 9000 and 5000 cal BP. (3) soil d13C indicates a forest expansion over savannas areas in Roraima (north), Mato Grosso and Rondonia (southwest), during the Holocene. (4) the mid-Holocene (8000- 4000 cal BP) is characterized by repeated occurrences of forest fires, marked by the presence of charcoals in soils and lacustrine sediments. However these different records are not characterized by abrupt transitions at the end of the Middle Holocene in Amazonia. In the Andean records there is a clear north-south shift in the timing of the transition. Analysis of coupled Ocean Atmosphere Model simulations suggest that convection in Amazon basin is directly controlled by insolation leading to an almost linear response of local climate to the global forcing. Differently, in the eastern and south-western regions where the rain is brought by the South American Monsoon, the climate transition appears more abrupt. It may be because the involved climate mechanisms are more complex and depend on Ocean/Atmosphere/Vegetation coupled process (ITCZ position, ZCAS formation, etc.). Tectonic movements or threshold links to

  10. Bosques montanos-relictos en Kañaris (Lambayeque, Perú

    Directory of Open Access Journals (Sweden)

    Santos Llatas-Quiroz

    2013-05-01

    Full Text Available En Kañaris (Lambayeque se encuentran grandes bosques relictos, probablemente los mayores de la vertiente occidental de los Andes peruanos. Actualmente están muy bien conservados, pero al mismo tiempo es la zona botánicamente menos estudiada de todos los bosques relictos de la zona. Estos bosques se ubican en las alturas de Upaypiteq y adyacentes a los flancos de la cordillera occidental de los Andes en la vertiente del Atlántico: Shin Shin, San Lorenzo, Huacapampa, Pandachí, Gramalote, Walte, Mollepampa; entre los 1500 a 3000 m sobre el nivel del mar, en el distrito de Kañaris (2300 m y los bosques de Chiñama y Luto en la vertiente del Pacífico. La presente investigación se emprendió con el objeto de estudiar científicamente, mediante muestreos florísticos, la vida y estructura de los componentes de los bosques de Upaypiteq. Las muestras conducen a un avance de la investigación, determinando que los principales componentes arbóreos corresponden a las Lauráceas: Persea, Ocotea y Nectandra, Cunoniáceas: Weinmannia, Podocarpáceas: Podocarpus, Cecropiáceas: Cecropia, Mirtáceas: Myrcianthes, Moráceas: Ficus, Rubiáceas: Cinchona, Bignoniáceas: Tabebuia, Arecáceas: Ceroxylon y, helechos arborescentes del género Nephelea. Circundantes a la masa boscosa se encuentran varias especies de arbustos, de los géneros Miconia, Munnozia, Baccharis, Senna, Colignonia, Gaiadendron, Oreopanax, etc.; también en la estructura es muy frecuente las epífitas y lianas ascendentes: Bromeliáceas, Orquídeas, Heliconias, Aráceas, musgos. Los helechos herbáceos, hongos, líquenes gelatinosos, hepáticas, Balanoforáceas y Begonias, tapizan por completo el piso boscoso. La composición florística es similar al bosque de Cutervo y los bosques de la Vertiente Oriental de los Andes, que a los demás bosques relictos en la Vertiente Occidental. La presencia de estos bosques se debe preservar, por su importancia en los procesos ecológicos para la

  11. Diversity and evolutionary origins of fungi associated with seeds of a neotropical pioneer tree: a case study for analysing fungal environmental samples.

    Science.gov (United States)

    U'ren, Jana M; Dalling, James W; Gallery, Rachel E; Maddison, David R; Davis, E Christine; Gibson, Cara M; Arnold, A Elizabeth

    2009-04-01

    Fungi associated with seeds of tropical trees pervasively affect seed survival and germination, and thus are an important, but understudied, component of forest ecology. Here, we examine the diversity and evolutionary origins of fungi isolated from seeds of an important pioneer tree (Cecropia insignis, Cecropiaceae) following burial in soil for five months in a tropical moist forest in Panama. Our approach, which relied on molecular sequence data because most isolates did not sporulate in culture, provides an opportunity to evaluate several methods currently used to analyse environmental samples of fungi. First, intra- and interspecific divergence were estimated for the nu-rITS and 5.8S gene for four genera of Ascomycota that are commonly recovered from seeds. Using these values we estimated species boundaries for 527 isolates, showing that seed-associated fungi are highly diverse, horizontally transmitted, and genotypically congruent with some foliar endophytes from the same site. We then examined methods for inferring the taxonomic placement and phylogenetic relationships of these fungi, evaluating the effects of manual versus automated alignment, model selection, and inference methods, as well as the quality of BLAST-based identification using GenBank. We found that common methods such as neighbor-joining and Bayesian inference differ in their sensitivity to alignment methods; analyses of particular fungal genera differ in their sensitivity to alignments; and numerous and sometimes intricate disparities exist between BLAST-based versus phylogeny-based identification methods. Lastly, we used our most robust methods to infer phylogenetic relationships of seed-associated fungi in four focal genera, and reconstructed ancestral states to generate preliminary hypotheses regarding the evolutionary origins of this guild. Our results illustrate the dynamic evolutionary relationships among endophytic fungi, pathogens, and seed-associated fungi, and the apparent

  12. Temporal and spatial resource use by female three-toed sloths and their young in an agricultural landscape in Costa Rica

    Directory of Open Access Journals (Sweden)

    Oscar Ramirez

    2011-12-01

    Full Text Available The information on ecological behavior of wild sloths is very scarce. In this study we determined the home ranges and resources used by three adult female three-toed sloths (Bradypus variegatus and their four young in an agricultural matrix of cacao (Theobroma cacao, pasture, riparian forests and living fencerows in Costa Rica. Births occurred during November-December and the young became independent at five to seven months of age. Initially, mothers remained fixed in one or a few trees, but expanded their use of resources as young sloths became independent from them. Mothers initially guided the young to preferred food and cover resources, but they gradually left their young in small nucleus areas and colonized new areas for themselves. Home range sizes for young sloths (up to seven months of age varied between 0.04-0.6 hectares, while home range sizes for mothers varied from 0.04-25.0 hectares. During the maternal care period, 22 tree species were used, with the most common being Cecropia obtusifolia (30.9%, Coussapoa villosa (25.6%, Nectandra salicifolia (12.1%, Pterocarpus officinalis (5.8% and Samanea saman (5.4%. However, young sloths used only 20 tree species, with the most common being C. villosa (18.4%, S. saman (18.5 % and N. salicifolia (16.7%. The cacao agroforest was used only by mother sloths and never by their young following separation. However, in the riparian forest, both mother sloths and young used the tree species. A total of 28 tree species were used by the mother sloth; including the food species: C. obtusifolia, C. villosa, N. salicifolia and P. officinalis. However, the young used 18 trees species in this habitat with N. salicifolia and S. saman most commonly used, although they rested and fed during the day in C. obtusifolia, C. villosa and O. sinnuata. The cacao agroforest with adjacent riparian forests and fencerows provides an important habitat type that links the smaller secondary forests and other patches. Rev

  13. Temporal and spatial resource use by female three-toed sloths and their young in an agricultural landscape in Costa Rica

    Directory of Open Access Journals (Sweden)

    Oscar Ramirez

    2011-12-01

    Full Text Available The information on ecological behavior of wild sloths is very scarce. In this study we determined the home ranges and resources used by three adult female three-toed sloths (Bradypus variegatus and their four young in an agricultural matrix of cacao (Theobroma cacao, pasture, riparian forests and living fencerows in Costa Rica. Births occurred during November-December and the young became independent at five to seven months of age. Initially, mothers remained fixed in one or a few trees, but expanded their use of resources as young sloths became independent from them. Mothers initially guided the young to preferred food and cover resources, but they gradually left their young in small nucleus areas and colonized new areas for themselves. Home range sizes for young sloths (up to seven months of age varied between 0.04-0.6 hectares, while home range sizes for mothers varied from 0.04-25.0 hectares. During the maternal care period, 22 tree species were used, with the most common being Cecropia obtusifolia (30.9%, Coussapoa villosa (25.6%, Nectandra salicifolia (12.1%, Pterocarpus officinalis (5.8% and Samanea saman (5.4%. However, young sloths used only 20 tree species, with the most common being C. villosa (18.4%, S. saman (18.5 % and N. salicifolia (16.7%. The cacao agroforest was used only by mother sloths and never by their young following separation. However, in the riparian forest, both mother sloths and young used the tree species. A total of 28 tree species were used by the mother sloth; including the food species: C. obtusifolia, C. villosa, N. salicifolia and P. officinalis. However, the young used 18 trees species in this habitat with N. salicifolia and S. saman most commonly used, although they rested and fed during the day in C. obtusifolia, C. villosa and O. sinnuata. The cacao agroforest with adjacent riparian forests and fencerows provides an important habitat type that links the smaller secondary forests and other patches. Rev

  14. Fontes e concentrações de águas de fumaça na germinação de sementes e no vigor de plântulas de tomate Sources and concentrations of smoke-water on the seed germination and seedling vigor of tomato

    Directory of Open Access Journals (Sweden)

    Yêda Maria BC Arruda

    2012-06-01

    Full Text Available A fumaça e a fumaça diluída em água, conhecida como água de fumaça, podem ser utilizadas como estimuladores tanto da germinação das sementes quanto do vigor das plântulas de várias espécies silvestres e cultivadas. O objetivo neste trabalho foi verificar a eficácia de águas de fumaça, oriundas de diferentes matérias-primas e concentrações, na germinação de sementes e vigor de plântulas de tomate. Foram usadas 10 matérias-primas e para cada uma foram testados um controle (água destilada e oito concentrações da água de fumaça (1:5.000, 1:2.500, 1:1.000, 1:100, 1:50, 1:25, 1:10 e 1:2,5 v:v, constituindo nove tratamentos, que foram repetidos oito vezes e distribuídos seguindo o delineamento experimental inteiramente casualizado. Os testes germinativos foram conduzidos no laboratório e as variáveis foram avaliadas após cinco dias da semeadura. Com a exceção de uma fonte, todas as matérias-primas testadas causaram, com a maior concentração testada (1:2,5, inibição na germinação das sementes de tomate. Efeito estimulador foi observado principalmente em águas de fumaça produzidas com matérias-primas de folhas de palmeira (Euterpe precatoria e de milho (Zea mays, com madeira leve de uma espécie pioneira (Cecropia palmata; serragem de espécies madeireiras amazônicas (Diniziaexcelsa, Sextonia sp., Licania spp. e Aniba spp. e de papel de germinação. Esse efeito foi mais expressivo no comprimento de raiz e no índice de vigor, nas concentrações de 1:25 a 1:5.000, de acordo com a fonte; a concentração de 1:25 sobressaiu na maioria das matérias-primas testadas.Smoke and smoke diluted in water, known as smoke-water, can be used to promote both seed germination and seedling vigor of several wild and cultivated species. The objective of this study was to assess the effectiveness of smoke-water produced with different sources (raw materials and concentrations on seed germination and seedling vigor of tomato

  15. Recuperação inteligente de jurisprudência: uma avaliação do raciocínio baseado em casos aplicado a recuperação de jurisprudências no Tribunal Regional Eleitoral do Distrito Federal

    Directory of Open Access Journals (Sweden)

    Symball Rufino de Oliveira

    2011-04-01

    Full Text Available Trata-se de uma pesquisa cujo objeto é avaliar a medida de precisão de um sistema de recuperação de informação jurídica (jurisprudência que utiliza técnica de inteligência artificial conhecida como Raciocínio Baseado em Casos (RBC. Nesse modelo as jurisprudências são organizadas sob a forma de casos jurídicos concretos. O raciocínio baseado em casos tem como princípio a idéias de que um caso jurídico passado pode ser útil para resolver um problema atual, desde que exista entre eles algum grau de semelhança. Para estabelecer semelhanças entre casos atuais e passados o modelo estudado propõe o uso de cálculo de similaridade que é realizado com base na comparação de índices temáticos obtidos a partir do processo de indexação realizado por especialistas utilizando-se como apoio um tesauro jurídico. Esta pesquisa utiliza como universo as jurisprudências produzidas pelo Tribunal Regional Eleitoral do Distrito Federal. A amostra foi composta, considerando o recorte dado à pesquisa, por jurisprudências eleitorais produzidas nas eleições gerais de 2006 no Distrito Federal. Para realizar a avaliação do modelo, foi construído um protótipo do sistema de recuperação de informação baseado em casos. Em seguida, avaliou-se o protótipo quanto ao grau de precisão obtido no resultado de um conjunto de buscas. O método adotado para as avaliações foi o mesmo utilizado na Text REtrieval Conference (TREC de 2007, tarefa Legal Track. Após a coleta dos dados foi elaborado um relatório discutindo a possibilidade do sistema de recuperação de informação baseado em casos ser considerado um paradigma para a recuperação de informação jurídica eleitoral.

  16. CryptoDex: a randomised, double-blind, placebo-controlled phase III trial of adjunctive dexamethasone in HIV-infected adults with cryptococcal meningitis: study protocol for a randomised control trial.

    Science.gov (United States)

    Day, Jeremy; Imran, Darma; Ganiem, Ahmed Rizal; Tjahjani, Natriana; Wahyuningsih, Retno; Adawiyah, Robiatul; Dance, David; Mayxay, Mayfong; Newton, Paul; Phetsouvanh, Rattanaphone; Rattanavong, Sayaphet; Chan, Adrienne K; Heyderman, Robert; van Oosterhout, Joep J; Chierakul, Wirongrong; Day, Nick; Kamali, Anatoli; Kibengo, Freddie; Ruzagira, Eugene; Gray, Alastair; Lalloo, David G; Beardsley, Justin; Binh, Tran Quang; Chau, Tran Thi Hong; Chau, Nguyen Van Vinh; Cuc, Ngo Thi Kim; Farrar, Jeremy; Hien, Tran Tinh; Van Kinh, Nguyen; Merson, Laura; Phuong, Lan; Tho, Loc Truong; Thuy, Pham Thanh; Thwaites, Guy; Wertheim, Heiman; Wolbers, Marcel

    2014-11-12

    . Ethical approval has been obtained from Oxford University's Tropical Research Ethics Committee (OxTREC), and as locally mandated at each site. International Standard Randomised Controlled Trial Number: ISRCTN59144167 26-July-2012.

  17. Nasa's Operation Icebridge and Remote Sensing Techniques in the K-12 Classroom as a STEM Integration Project

    Science.gov (United States)

    McCarthy, K.

    2017-12-01

    NASA's Operation IceBridge (OIB), the largest airborne survey of Earth's polar ice uses remote sensing methods to collect data on changing sea and land ice. PolarTREC teacher Kelly McCarthy joined the team during the 2016 Spring Arctic Campaign. This presentation explores ways in which k-12 students were engaged in the work being done by OIB through classroom learning experiences, digital communications, and independent research. Initially, digital communication including chats via NASA's Mission Tools Suite for Education (MTSE) platform was leveraged to engage students in the daily work of OIB. Two lessons were piloted with student groups during the 2016-2017 academic year both for students who actively engaged in communications with the team during the expedition and those who had no prior connections to the field. All of the data collected on OIB missions is stored for public use in a digital portal on the National Snow and Ice Data Center (NSIDC) website. In one lesson, 10th-12th grade students were guided through a tutorial to learn how to access data and begin to develop a story about Greenland's Jakobshavn Glacier using pre-selected data sets, Google's MyMaps app, and independent research methods. In the second lesson, 8th grade students were introduced to remote sensing, first through a discussion on vocabulary using productive talk moves and then via a demonstration using Vernier motion detectors and a graph matching simulation. Students worked in groups to develop procedures to map a hidden surface region (boxed assortment of miscellaneous objects) using a Vernier motion sensor to simulate sonar. Students translated data points collected from the motion sensor into a vertical profile of the simulated surface region. Both lessons allowed students a way to engage in two of the most important components of OIB. The ability to work with real data collected by the OIB team provided a unique context through which students gained skill and overcame challenges in

  18. Expanding Horizons Teachers and Scientists Collabortaing

    Science.gov (United States)

    Teres, A.

    2017-12-01

    As a participant in PolarTrec, I joined the crew of NASA's Operation IceBridge in Greenland for the month of April 2017. As an active member of the team I learned the ins and outs of field research, and I learned about the work done by Operation IceBridge. As a result of participating in this project, I grew as a teacher and a scientist. I took my experiences and shared them with my classroom through stories, pictures, videos, and my lesson plans. By seeing the Artic through my experiences the class became enraptured by the subject matter. I was no longer talking about a distant or abstract place instead I was talking about an experience. This enabled my students to take an active part in the discussion and to feel like the cryosphere was part of their life too. Not only did I learn about the science but I leaned about logistics of field research. I reached out to my community and local communications outlets before and after my trip to Greenland to familiarize whomever I could connect with about my experience. I contacted a local news station and they did an interview with me about my trip. I emailed a local newspaper about my trip and was interviewed before I left and after I returned. Due to the newscast, I was contacted by my college sorority and was interviewed for the sorority's national newsletter which is distributed throughout the United States. Each connection helped to spread the word. I'm continuing to spread the word by volunteering to present my experience to schools throughout Broward County in Florida. I've already connected with teachers and schools to set up my presentation in the calendar. Having these types of experiences is critical for teachers to continue their growth within the scientific field and education. Effective teachers are those not constrained by the walls of their classroom. Having the opportunity to work with scientists and do research in the field has expanded my horizons. The people I met I am still in contact with and I am

  19. Importanţa testului de transformare limfoblastică – indicator al imunităţii celulare

    Directory of Open Access Journals (Sweden)

    GOLBAN Rita

    2015-12-01

    Full Text Available This paper includes scientific research results related to the lymphoblastic transformation test (LTT “in vitro” under the action of anticarburising antigens and purified protein derivative, as a result of stimulation of lymphocytes which are central cells of the immune system. It was studied the mechanism of the stimulated lymphocytes blastization, which proliferates due to their mitosis and it was practically determined a cellular population, which corresponds numerically and functionally to an immune high quality answer. At the same time, it was stated that due to blast transformations, lymphocytes leave the stage of immunological inactivity and pass to the kinetic stage, being capable to produce specific effects, both on other cells they cooperate with and on the antigenic substrate, which causes immunological reactions. We have also observed activated macrophage changes after the re-vaccination in young animals with 15.5 % of blasts, compared to the reference sample where stimulation indices were 3.5 %. Modifications of the nonspecific blast are necessary to evaluate the functional capacity of lymphocytes. Rezumat. În lucrare sunt redate rezultatele investigaţiilor ştiinţifice cu privire la efectuarea testului de transformare limfoblastică (LTT „ in vitro” sub acţiunea antigenilor anticarbunos şi protein purified derivative, ca rezultat al stimulării limfocitelor, celule centrale ale sistemului imunitar. S-a studiat mecanismul blastizării limfocitelor stimulate care proliferează datorită mitozelor acestora şi s-a determinat practic o populaţie celulară ce corespunde numeric şi funcţional unui răspuns imun de un nivel înalt calitativ. De asemenea s-a constatat că, graţie transformărilor blastice, limfocitele părăsesc starea de inactivitate imunologică şi trec în starea cinetică, devenind capabile să producă efecte specifice atât asupra altor celule cu care cooperează, cât şi asupra substratului

  20. Allogeneic stem cell transplantation for X-linked agammaglobulinemia using reduced intensity conditioning as a model of the reconstitution of humoral immunity.

    Science.gov (United States)

    Ikegame, Kazuhiro; Imai, Kohsuke; Yamashita, Motoi; Hoshino, Akihiro; Kanegane, Hirokazu; Morio, Tomohiro; Kaida, Katsuji; Inoue, Takayuki; Soma, Toshihiro; Tamaki, Hiroya; Okada, Masaya; Ogawa, Hiroyasu

    2016-02-13

    peripheral blood (PB) of the patient on day 279 showed sufficient proliferation after a CD40L and IL-21 or CD40L and CpG stimulation. Effective immunoglobulin production and class switching were also observed after a CD40L and IL-21 or CpG stimulation. Signal joint kappa-deleting recombination excision circles (sjKRECs) became positive 16 days post-SCT, increased to 6300 copies/μg DNA at 42 days, and were maintained at a high level thereafter. The recovery of T-cell receptor excision circles (TRECs) was slow, but became detectable 1 year post-hematopoietic stem cell transplantation (HSCT).

  1. UNCOVERING THE NUCLEUS CANDIDATE FOR NGC 253

    Energy Technology Data Exchange (ETDEWEB)

    Günthardt, G. I.; Camperi, J. A. [Observatorio Astronómico, Universidad Nacional de Córdoba (Argentina); Agüero, M. P. [Observatorio Astronómico, Universidad Nacional de Córdoba, and CONICET (Argentina); Díaz, R. J.; Gomez, P. L.; Schirmer, M. [Gemini Observatory, AURA (United States); Bosch, G., E-mail: gunth@oac.uncor.edu, E-mail: camperi@oac.uncor.edu, E-mail: mpaguero@oac.uncor.edu, E-mail: rdiaz@gemini.edu, E-mail: pgomez@gemini.edu, E-mail: mschirmer@gemini.edu, E-mail: guille@fcaglp.unlp.edu.ar [Instituto de Astrofísica de La Plata (CONICET-UNLP) (Argentina)

    2015-11-15

    NGC 253 is the nearest spiral galaxy with a nuclear starburst that becomes the best candidate for studying the relationship between starburst and active galactic nucleus activity. However, this central region is veiled by large amounts of dust, and it has been so far unclear which is the true dynamical nucleus to the point that there is no strong evidence that the galaxy harbors a supermassive black hole co-evolving with the starburst as was supposed earlier. Near-infrared (NIR) spectroscopy, especially NIR emission line analysis, could be advantageous in shedding light on the true nucleus identity. Using Flamingos-2 at Gemini South we have taken deep K-band spectra along the major axis of the central structure and through the brightest infrared source. In this work, we present evidence showing that the brightest NIR and mid-infrared source in the central region, already known as radio source TH7 and so far considered just a large stellar supercluster, in fact presents various symptoms of a genuine galactic nucleus. Therefore, it should be considered a valid nucleus candidate. Mentioning some distinctive aspects, it is the most massive compact infrared object in the central region, located at 2.″0 of the symmetry center of the galactic bar, as measured in the K-band emission. Moreover, our data indicate that this object is surrounded by a large circumnuclear stellar disk and it is also located at the rotation center of the large molecular gas disk of NGC 253. Furthermore, a kinematic residual appears in the H{sub 2} rotation curve with a sinusoidal shape consistent with an outflow centered in the candidate nucleus position. The maximum outflow velocity is located about 14 pc from TH7, which is consistent with the radius of a shell detected around the nucleus candidate, observed at 18.3 μm (Qa) and 12.8 μm ([Ne ii]) with T-ReCS. Also, the Brγ emission line profile shows a pronounced blueshift and this emission line also has the highest equivalent width at this

  2. Thymic function and T cell parameters in a natural human experimental model of seasonal infectious diseases and nutritional burden

    Directory of Open Access Journals (Sweden)

    Morgan Gareth

    2011-06-01

    Full Text Available Abstract Background The study exploits a natural human experimental model of subsistence farmers experiencing chronic and seasonally modified food shortages and infectious burden. Two seasons existed, one of increased deprivation and infections (Jul-Dec, another of abundance and low infections (Jan-Jun; referred to as the hungry/high infection and harvest/low infection seasons respectively. Prior analysis showed a 10-fold excess in infectious disease associated mortality in young adults born in the hungry/high infection versus harvest/low infection season, and reduced thymic output and T cell counts in infancy. Here we report findings on the role of early life stressors as contributors to the onset of T cell immunological defects in later life. Methods We hypothesised that season of birth effects on thymic function and T cell immunity would be detectable in young adults since Kaplan-Meier survival curves indicated this to be the time of greatest mortality divergence. T cell subset analyses by flow-cytometry, sjTRECs, TCRVβ repertoire and telomere length by PCR, were performed on samples from 60 males (18-23 y selected to represent births in the hungry/high infection and harvest/low infection Results Total lymphocyte counts were normal and did not differ by birth season. CD3+ and CD4+ but not CD8+ counts were lower for those born during the hungry/high infection season. CD8+ telomere length also tended to be shorter. Overall, CD8+ TCRVβ repertoire skewing was observed with 'public' expressions and deletions seen in TCRVβ12/22 and TCRVβ24, respectively but no apparent effect of birth season. Conclusions We conclude that, although thymic function was unchanged, the CD4+ and CD3+ counts, and CD8+ telomere length results suggested that aspects of adult T cell immunity were under the influence of early life stressors. The endemicity of CMV and HBV suggested that chronic infections may modulate immunity through T cell repertoire development. The

  3. Soil and biomass carbon pools in model communities of tropical plants under elevated CO2.

    Science.gov (United States)

    Arnone, J A; Körner, Ch

    1995-09-01

    plant-derived soil organic matter)-averaged 815 and 910 g m -2 year -1 at ambient and elevated CO 2 , respectively. These NPPs are remarkably similar to those of many natural moist tropical forested ecosystems. At the same time net productivity of soil organic matter reached 7000 g dry matter equivalent per m 2 and year (i.e. 3500 g C m -2 year -1 ). Very slight yet statistically significant CO 2 -induced shifts in the abundance of groups of species occurred by the end of the experiment, with one group of species (Elettaria cardamomum, Ficus benjamina, F. pumila, Epipremnum pinnatum) gaining slightly, and another group (Ctenanthe lubbersiana, Heliconia humilis, Cecropia peltata) losing. Our results show that: (1) enormous amounts of C can be deposited in the ground which are normally not accounted for in estimates of NPP and net ecosystem productivity; (2) any enhancement of C sequestration under elevated atmospheric CO 2 may be substantially smaller than is believed will occur (yet still very important), especially under growth conditions which permit close to natural NPP; and (3) species dominance in plant communities is likely to change under elevated CO 2 , but that changes may occur rather slowly.

  4. COMPOSIÇÃO E DENSIDADE DO BANCO DE SEMENTES EM UMA FLORESTA DE VÁRZEA, ILHA DO COMBU, BELÉM-PA, BRASIL

    Directory of Open Access Journals (Sweden)

    Arthur Viana Lau

    2014-10-01

    Full Text Available Este estudo teve como objetivo caracterizar a composição e densidade do banco de sementes de um trecho de floresta de várzea localizada na Área de Proteção Ambiental (APA Ilha do Combu, no município de Belém, PA, Brasil. Foram alocadas sistematicamente 6 parcelas de 20 x 20m em três áreas da floresta distante 100m uma da outra perfazendo um total de 0,24ha. Em cada parcela foi utilizado um gabarito de madeira medindo 50 x 50 cm para a padronização e coleta de 20 amostras do banco de sementes do solo a 20 cm de profundidade desprezando-se a serapilheira. As 120 amostras foram depositadas em sacos plásticos de 30 litros e transportadas para o Horto Botânico localizado no campus de pesquisa do Museu Paraense Emílio Goeldi (MPEG. As amostras foram distribuídas em recipientes plásticos medindo 36 cm x 5 cm de profundidade em um viveiro suspenso com sombrite a 50%. O experimento foi conduzido de maio a agosto de 2013 com a quantificação das plântulas a partir de 10 cm de altura e identificadas em nível de família, gênero, espécie e calculada a densidade média de plântulas. Para comparar a diversidade de espécies foram utilizados o índice de diversidade de Shannon-Wiener (H' e o índice de similaridade de Sorensen (S. Foram registradas 26 famílias, 38 gêneros e 41 espécies. As famílias mais representativas foram Poaceae, Asteraceae e Cyperaceae com quatro espécies cada e as espécies com maiores densidades foram Polybotrya caudata Kunze, Cecropia palmata Willd., Cyperus difformis L., Alternanthera tenella, Clidemia hirta (L. D. Don, Commelina erecta L. e Phyllanthus niruri L. A forma de crescimento herbácea foi dominante em todas as áreas. Foi registrado o índice de H'=0,86 nat-3ind para a área 1; H'=1,91 nats-3ind para a área 2 e H'=1,35 nats-3ind para a área 3 e a similaridade de S'=0,50 para a área 1; S'=0,48 para a área 2 e S'=0,50 para a área 3. A composição florística do banco de sementes foi

  5. 跨語言資訊檢索:理論、技術與應用 | Cross-Language Information Retrieval: Theories and Technologies

    Directory of Open Access Journals (Sweden)

    陳信希 Hsin-His Chen

    2002-04-01

    Full Text Available

    頁次:19-32

    多語性是網路社會的重要特徵之一,如何將網路資源,介紹給不同語言的使用者,同時吸收其他語言所呈現的資訊,都是資訊國際化不能忽略的重要課題。跨語言資訊檢索,提供使用者以某種語言檢索另外一種語言表達的文件,為近年來很活躍的研究題目之一。本文嘗試將這個研究主題相關的理論和技術,介紹給有興趣的讀者。首先探討詢問翻譯、文件翻譯、和不翻譯等三類基本方法。接著考慮翻譯歧義性和目標多義性,以及專有名詞音譯等進階方法。評估是促進技術進步的必要工作,本文最後也介紹跨語言資訊檢索三大評比:TREC CLEF、與 NTCIR

    Multilinguality is one

  6. Existing data sources in clinical epidemiology: the Scandinavian Thrombosis and Cancer Cohort

    Directory of Open Access Journals (Sweden)

    Jensvoll H

    2015-09-01

    Full Text Available Hilde Jensvoll,1,2 Marianne T Severinsen,3,4 Jens Hammerstrøm,5 Sigrid K Brækkan,1,2 Søren R Kristensen,4,6 Suzanne C Cannegieter,7 Kristine Blix,1,2 Anne Tjønneland,8 Frits R Rosendaal,1,7,9 Olga Dziewiecka,1 Kim Overvad,10,11 Inger Anne Næss,12 John-Bjarne Hansen1,21Department of Clinical Medicine, KG Jebsen – Thrombosis Research and Expertise Center (TREC, UiT – The Arctic University of Norway, 2Division of Internal Medicine, University Hospital of North Norway, Tromsø, Norway; 3Department of Hematology, Aalborg University Hospital, 4Department of Clinical Medicine, Aalborg University, Aalborg, Denmark; 5Department of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway; 6Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark; 7Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands; 8Diet, Genes and Environment, Danish Cancer Society Research Center, Copenhagen, Denmark; 9Department of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, the Netherlands; 10Department of Cardiology, Aalborg University Hospital, Aalborg, 11Department of Public Health, Section for Epidemiology, Aarhus University, Aarhus, Denmark; 12Department of Hematology, Trondheim University Hospital, Trondheim, NorwayBackground: Although venous thromboembolism (VTE is a known common complication in cancer patients, there is limited knowledge on patient-related and cancer-specific risk factors in the general population. The Scandinavian Thrombosis and Cancer (STAC Cohort was established by merging individual data from three large Scandinavian cohorts (The Tromsø Study, the second Nord-Trøndelag Health Study, and the Danish Diet, Cancer and Health Study. Here, we present the profile of the STAC cohort and provide age-specific incidence rates of VTE and cancerMethods: The STAC cohort includes 144,952 subjects aged 19–101 years

  7. Allogeneic stem cell transplantation for X-linked agammaglobulinemia using reduced intensity conditioning as a model of the reconstitution of humoral immunity

    Directory of Open Access Journals (Sweden)

    Kazuhiro Ikegame

    2016-02-01

    -cells were observed between the patient and healthy control. B-cells in the peripheral blood (PB of the patient on day 279 showed sufficient proliferation after a CD40L and IL-21 or CD40L and CpG stimulation. Effective immunoglobulin production and class switching were also observed after a CD40L and IL-21 or CpG stimulation. Signal joint kappa-deleting recombination excision circles (sjKRECs became positive 16 days post-SCT, increased to 6300 copies/μg DNA at 42 days, and were maintained at a high level thereafter. The recovery of T-cell receptor excision circles (TRECs was slow, but became detectable 1 year post-hematopoietic stem cell transplantation (HSCT.

  8. Spectroscopic Evidence for the Asteroidal Nature of the July 2009 Jovian Impactor

    Science.gov (United States)

    Lisse, Carey; Orton, Glenn; Yanamandra-Fisher, Padma; Fletcher, Leigh; Depater, Imke; Hammel, Heidi

    2010-05-01

    The collision of a large object with Jupiter on July 19, 2009, heated its atmosphere, modified its composition and generated a prominent field of deposited particulate debris. Low-resolution 7-24 μm spectroscopy of the impact field obtained using the T-ReCS mid-infrared camera/spectrometer on Gemini/South on 24 July 2009 has revealed an excess 9-μm absorption in the impact debris in addition to that supplied by hot ammonia created in the impact. We have searched for candidate materials that would best fit the spectral feature near 9 μm, and find that the feature cannot be matched with candidate materials in Jupiter's atmosphere. A search through a large suite of gaseous and solid absorption spectra (c.f Lisse et al. 2008, 2009) revealed that the major competent matches were for (a) obsidian, a glassy silica, and (b) quartz and cristobalite, crystalline silicas, kinetic alteration products of primitive body ferromagnesian silicates formed at high pressures and temperatures over 1500 K. There are also weak features at 10 - 11 um consistent with olivine absorptions. While the high temperatures required to create silicas are also high enough to destroy the non-refractory water and organics dominating icy cometary bodies, and thus destroy their spectral signal, there was no detectable absorption due to pyroxene materials, which, along with olivines in roughly equal measure, comprise the majority of refractory silicaceous species found in comets (Lisse et al. 2007). This suggests that the impacting body was not a comet, but an olivine-rich differentiated body similar to asteroids that are abundant in the outer regions of the main asteroid belt (Lodders and Fegley 1998). We speculate that the weak structural strength of bulk cometary material causes a comet impactor to catastrophically disrupt at higher altitudes and lower temperatures than a strong, dense asteroidal body, so that the cometary refractory dust component remains relatively cold and unaltered through

  9. Editorial

    Directory of Open Access Journals (Sweden)

    André Luis Calado Araújo

    2010-07-01

    alternativa (georremediação aditivada, GAD para melhorar substancialmente a degradação da matéria orgânica recalcitrante contida no chorume, associada a uma redução significativa nas concentrações de alguns metais pesados do efluente. O quinto trabalho, elaborado por pesquisadores da UFOPA, discorre sobre os Cepropiais nativos formados pela espécie Cecropia palmata, dentre outras, que, acumulando fósforo (P em tecidos foliares e cascas, podem prestar um serviço ecológico em paisagens amazônicas com deficiência desse elemento químico. De autoria de pesquisadores do IFRN, o artigo de número seis trata do diagnóstico da qualidade sanitária de plantas medicinais comercializadas em Currais Novos/RN. Os resultados mostram contaminações por grupos, contagens de bactérias do grupo dos coliformes totais, e os níveis de contaminação registrados apontam o material analisado como potencialmente danoso à saúde humana. O sétimo artigo, por sua vez, é fruto de uma cooperação entre pesquisadores do IFRN e da UFPE, que apresentam resultados de estudos no controle ambiental de perfuração de poços de petróleo no Campo de Porto Carão, Carnaubais/RN. O trabalho analisa as limitações do Relatório de Controle Ambiental. Voltado para o desenvolvimento sustentável do turismo, o oitavo artigo discute o tema e verifica que a atividade turística de Natal se constitui em alternativa viável de desenvolvimento, observando, no entanto, que o novo poder local deve desempenhar o seu papel de fomentador e protagonista do desenvolvimento socioeconômico. O artigo seguinte traz uma discussão sobre os resíduos eletrônicos de computadores nas Instituições de ensino superior em Natal/RN, observando que sua gestão é incipiente. Os autores são oriundos da UFRN, da UnP e da UNESP. Apresentado por pesquisadores da UFRN, o décimo artigo examinam conceitos e aspectos da Gerência do Conhecimento que possam contribuir no desenvolvimento de ferramentas mais adaptadas para