WorldWideScience

Sample records for cd-rom periodical indexes

  1. HRM Cd-ROM

    NARCIS (Netherlands)

    drs. C.A.G. Huijsmans; ir. R.B. Opsteeg; drs. H.J.J.L. Seegers

    2006-01-01

    De cd-rom HRM biedt een compleet en actueel overzicht van het totale HRM-gebied. Het bevat een unieke verzameling informatie over personeelsmanagement en sociaal beleid. Deze cd-rom geeft richtlijnen, maatregelen en handige tips op het gebied van personeelsmanagement. Het is samen met het zakboek de

  2. Creating Virtual CD-ROM Collections

    Directory of Open Access Journals (Sweden)

    Kam Woods

    2009-10-01

    Full Text Available Over the past 20 years, more than 100,000 CD-ROM titles have been published including thousands of collections of government documents and data. CD-ROMs present preservation challenges at the bit level and in ensuring usability of the preserved artifact. We present techniques we have developed to archive and support user access to a collection of approximately 2,900 CD-ROMs published under the Federal Depository Library Program (FDLP by the United States Government Printing Office (GPO. The project provides web-based access to CD-ROM contents using both migration and emulation and supports remote execution of the raw CD-ROM images. Our project incorporates off-the-shelf, primarily open-source software. The raw data and (METS metadata are made available through AFS, a standard distributed file system, to encourage sharing among libraries.

  3. CD-ROMs in Astronomy

    Science.gov (United States)

    Robertson, K.

    The CD-ROM has become a major data storage medium in astronomy. The release of the Digitized Sky Survey is the most recent example of this phenomena. I will summarize the large scale jukebox technologies available for making the DSS available over LANs (Local Area Networks). I will also give an overview of the developments in disciplines such as medicine, chemistry and business, where CD-ROMs have been used to distribute the full text of journals. These factors may give us insights into the future role of CD-ROMs.

  4. CD-ROM-aided Databases

    Science.gov (United States)

    Masuyama, Keiichi

    CD-ROM has rapidly evolved as a new information medium with large capacity, In the U.S. it is predicted that it will become two hundred billion yen market in three years, and thus CD-ROM is strategic target of database industry. Here in Japan the movement toward its commercialization has been active since this year. Shall CD-ROM bussiness ever conquer information market as an on-disk database or electronic publication? Referring to some cases of the applications in the U.S. the author views marketability and the future trend of this new optical disk medium.

  5. Getting the Most from Your CD-ROM Dollars: The CD-ROM Bundle [and] The Pros and Cons of CD-ROM Bundling.

    Science.gov (United States)

    Sarjeant, Eric W.; O'Connor, Mary Ann

    1992-01-01

    Discusses and reviews CD-ROM bundles--i.e., hardware, software and CD-ROM kits--including their features, specifications, drawbacks, and prices. Recommends buying through mail order for the best selection and price. The pros and cons of bundling as a marketing strategy are discussed and a list of vendors is provided. (EA)

  6. CD-RW/DVD-ROM drive SD-R1002; CD-RW/DVD-ROM drive SD-R1002

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    With the availability of DVD programs increasing at a rapid rate, it has become a general practice to equip a personal computer with a DVD-ROM drive. Toshiba, with a view to meeting the sharp increase in the demand for CD-R/RW (Recordable/ReWritable) recording these days, has commercialized a CD-R/RW drive capable of DVD-ROM reproduction and thereby newly entered into the CD-R/RW drive market. The new product is characterized by (1) the height halved to 41.5mm, (2) quad-speed CD-R/RW recording, (3) 24-speed CD-ROM playback at the maximum, (4) 4.8-speed DVD-ROM playback at the maximum, (5) ATAPI (AT Packet Interface) interface, and (6) access at high speeds, 160ms for DVD and 110ms for CD. (translated by NEDO)

  7. Annelids. A Multimedia CD-ROM. [CD-ROM].

    Science.gov (United States)

    2001

    This CD-ROM is designed for classroom and individual use to teach and learn about annelids. Integrated animations, custom graphics, three-dimensional representations, photographs, and sound are featured for use in user-controlled activities. Interactive lessons are available to reinforce the subject material. Pre- and post-testing sections are…

  8. The Nuclear CD-Rom

    International Nuclear Information System (INIS)

    James, J.Z.

    1993-01-01

    September 1992 will see the publication of the first open-quotes Nuclear CD-ROMclose quotes-a Compact Disk Read-Only Memory (CD-ROM) containing both the entire Evaluated Nuclear Data Files (ENDF) library and the Evaluated Nuclear Structure Data Files (ENSDF) library. The CD-ROM will also contain codes for processing and visualizing the data, and some nuclear physics codes to use the ENDF data. Finally, the data and program files will be accompanied by fully-formatted documentation that can be read on many different workstations and microcomputers

  9. SCUTREA Conference Proceedings, 1970-1997. 25th Anniversary CD-ROM.

    Science.gov (United States)

    Standing Conference on Univ. Teaching and Research in the Education of Adults.

    This CD-ROM contains 693 papers on university teaching and research in the education of adults that were presented during the 27-year period from 1970 through 1997. The CD-ROM is designed to be used with the Macintosh, Windows 95, and Windows 3.1 operating systems and Adobe Acrobat Portable Document Format (version 3), which is included along with…

  10. The Novice User and CD-ROM Database Services. ERIC Digest.

    Science.gov (United States)

    Schamber, Linda

    This digest answers the following questions that beginning or novice users may have about CD-ROM (a compact disk with read-only memory) database services: (1) What is CD-ROM? (2) What databases are available? (3) Is CD-ROM difficult to use? (4) How much does CD-ROM cost? and (5) What is the future of CD-ROM? (15 references) (MES)

  11. Distributing the Wealth: Sliding CD-ROM into the Consumer Channel.

    Science.gov (United States)

    Bowers, Richard A.

    1994-01-01

    Examines retail sales of CD-ROMs. Topics addressed include the current situation in CD-ROM retailing; channel distribution options; myths and realities of CD-ROM distribution; the distributor; affiliate labels; sales representatives; copublishers; distribution options; distributing resources; and recommendations for new CD-ROM publishers. (LRW)

  12. Food Chains & Webs. A Multimedia CD-ROM. [CD-ROM].

    Science.gov (United States)

    2001

    This CD-ROM is designed for classroom and individual use to teach and learn about food chains and food webs. Integrated animations, custom graphics, three-dimensional representations, photographs, and sound are featured for use in user-controlled activities. Interactive lessons are available to reinforce the subject material. Pre- and post-testing…

  13. The planetary data system educational CD-ROM

    Science.gov (United States)

    Guinness, E. A.; Arvidson, R. E.; Martin, M.; Dueck, S.

    1993-01-01

    The Planetary Data System (PDS) is producing a special educational CD-ROM that contains samples of PDS datasets and is expected to be released in 1993. The CD-ROM will provide university-level instructors with PDS-compatible materials and information that can be used to construct student problem sets using real datasets. The main purposes of the CD-ROM are to facilitate wide use of planetary data and to introduce a large community to the PDS. To meet these objectives the Educational CD-ROM will also contain software to manipulate the data, background discussions about scientific questions that can be addressed with the data, and a suite of exercises that illustrate analysis techniques. Students will also be introduced to the SPICE concept, which is a new way of maintaining geometry and instrument information. The exercises will be presented at the freshman through graduate student levels. With simplification, some of the material should also be of use at the high school level.

  14. CD-ROM Stress.

    Science.gov (United States)

    Bunge, Charles A.

    1991-01-01

    Discussion of stress in library reference departments focuses on stress caused by CD-ROM reference tools. Topics discussed include work overload; nonreference duties; patron attitudes and behavior; staff attitudes; the need for proper staff training; and the need for library administrators to be sensitive to reference staff needs. (LRW)

  15. Educational use of World Wide Web pages on CD-ROM.

    Science.gov (United States)

    Engel, Thomas P; Smith, Michael

    2002-01-01

    The World Wide Web is increasingly important for medical education. Internet served pages may also be used on a local hard disk or CD-ROM without a network or server. This allows authors to reuse existing content and provide access to users without a network connection. CD-ROM offers several advantages over network delivery of Web pages for several applications. However, creating Web pages for CD-ROM requires careful planning. Issues include file names, relative links, directory names, default pages, server created content, image maps, other file types and embedded programming. With care, it is possible to create server based pages that can be copied directly to CD-ROM. In addition, Web pages on CD-ROM may reference Internet served pages to provide the best features of both methods.

  16. CD-ROM-aided Databases

    Science.gov (United States)

    Kusama, Hideo; Matsumoto, Toshiaki

    The CD-ROM system can be used independently or as a compliment to an on-line data system. It has many of the same features as an on-line system. Nippan developed the CD-NOCS system as a reinforcement or substitute for the on-line systems of the customers (bookstores). CD-NOCS is not necessarily designed just for bookstores, it is also applicable to libraries and companies. Authors would also like to emphasize that it is important to understand the development and background of the CD-NOCS system, as well as its operations.

  17. Energy & Environmental Issues Interactive CD-ROM. Version 2.0. [CD-ROM].

    Science.gov (United States)

    Florida State Univ., Tallahassee.

    This CD-ROM presents various energy and environmental topics. "Great Energy Debate" uses video clips to explore the pros and cons of solar, coal, nuclear, and oil energy sources. "Energy Plant Tour" presents a virtual tour through a plant that converts solid waste into energy. "How Stuff Works" explains energy…

  18. DNA: The Molecule of Life. A Multimedia CD-ROM. [CD-ROM].

    Science.gov (United States)

    2001

    This CD-ROM is designed for classroom and individual use to teach and learn about DNA. Integrated animations, custom graphics, three-dimensional representations, photographs, and sound are featured for use in user-controlled activities. Interactive lessons are available to reinforce the subject material. Pre- and post-testing sections are also…

  19. CD-ROM: towards a strategy for teaching and learning.

    Science.gov (United States)

    Aarvold, J; Walton, G

    1992-12-01

    Compact Disc Read Only Memory (CD-ROM) represents an exciting innovation in nurse education yet paradoxically has a potential to induce disillusionment and frustration. Purchasers of systems may well find that their investment does not bring the benefits they had been lead to expect. CD-ROM systems have the capacity to generate huge quantities of data on an equally large number of nursing topics. Arguably this very capability ensures certain 'built-in' problems. The purpose of this articles is to provide nurse teachers with information about CD-ROM, to highlight the resource implications of CD-ROM use and to consider the relative merits of various teaching and learning methods. To be worthwhile, strategies developed must be part of an information retrieval skills programme.

  20. Enhancing Your CD-ROM Services with Signage Systems.

    Science.gov (United States)

    Ekhaml, Leticia

    1994-01-01

    Describes how to use effective signage, or visual guidance, for more efficient use of CD-ROM technology in elementary and secondary school library media centers. Setting CD-ROM policies and procedures is considered; the use of posters, brochures, flowcharts, and other formats is discussed; and examples are included. (LRW)

  1. Students' Attitudes toward ABI/INFORM on CD-ROM: A Factor Analysis.

    Science.gov (United States)

    Wang, Vicky; Lau, Shuk-fong

    Two years after the introduction of CD-ROM bibliographic database searching in the Memphis State University libraries (Tennessee), a survey was conducted to examine students' attitudes toward the business database, ABI/INFORM. ABI/INFORM contains indexes and abstracts of articles from over 800 journals on management, accounting, banking, human…

  2. In Praise of Mr. S. Platter and His Marvelous, Magnificent CD ROM Laser Disc Index for ERIC and PSYCHLIT.

    Science.gov (United States)

    Huffman, Robert F.

    These instructions are designed to help patrons of the University of Missouri-Columbia library perform searches on PSYCHLIT, a CD-ROM (compact disc, read only memory) version of the Psych Abstracts database, and a CD-ROM version of the ERIC database, both produced by SilverPlatter Information Services. Basic information is provided about the disk…

  3. CD-ROM storing JENDL-3.2 plots and data

    Energy Technology Data Exchange (ETDEWEB)

    Fukahori, Tokio; Iwamoto, Osamu; Nakagawa, Tsuneo; Shibata, Keiichi; Narita, Tsutomu; Katakura, Jun-ichi; Hasegawa, Akira [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1998-01-01

    Numerical data and graphs of Japanese Evaluated Nuclear Data Library, Version 3, Revision 2 (JENDL-3.2) have been stored into CD-ROM. JENDL-3.2 is an evaluated nuclear data library which is highly rated in the world, and consists of neutron nuclear data and secondary gamma-ray data for 340 nuclides. JENDL-3.2 has been already released through World Wide Web (WWW, http://cracker.tokai.jaeri.go.jp). For users` convenience and to promote further utilization, this CD-ROM has been produced. The data stored in CD-ROM are the original data and point-wise data (0 K and 300 K) of JENDL-3.2 and graphs of cross sections in gif, PostScript and PDF formats. These data can be retrieved by users` personal computers and engineering workstations, and also can be seen by using WWW browsers. This CD-ROM makes user completely free from downloading, which takes a lot of time, and tedious management such a treating big amount of data. (author)

  4. Scaffolding or Distracting: CD-ROM Storybooks and Young Readers

    Science.gov (United States)

    Pearman, Cathy J.; Chang, Ching-Wen

    2010-01-01

    CD-ROM storybooks, often referred to as electronic texts, e-books, and interactive stories, are learning tools with supplemental features such as automatic reading of text, sound effects, word pronunciations, and graphic animations which support the development of reading skills and comprehension in beginning readers. Some CD-ROM storybooks also…

  5. Review of CD Rom

    African Journals Online (AJOL)

    "The Virtual Surgeon consists of a ground breaking series of CD-ROMs, which aims to provide surgeons with a new and powerful training tool. It provides surgeons with the most accurate and realistic model of the knee available, and our developments in animation allow them to see all aspects of the surgical procedure.

  6. Managing nuclear knowledge: IAEA activities and international coordination. Including resource material full text CD-ROM

    International Nuclear Information System (INIS)

    2005-06-01

    The present CD-ROM summarizes some activities carried out by the Departments of Nuclear Energy and Nuclear Safety and Security in the area of nuclear knowledge management in the period 2003-2005. It comprises, as open resource, most of the relevant documents in full text, including policy level documents, reports, presentation material by Member States and meeting summaries. The collection starts with a reprint of the report to the IAEA General Conference 2004 on Nuclear Knowledge [GOV/2004/56-GC(48)/12] summarizing the developments in nuclear knowledge management since the 47th session of the General Conference in 2003 and covers Managing Nuclear Knowledge including safety issues and Information and Strengthening Education and Training for Capacity Building. It contains an excerpt on Nuclear Knowledge from the General Conference Resolution [GC(48)/RES/13] on Strengthening the Agency's Activities Related to Nuclear Science, Technology and Applications. On the CD-ROM itself, all documents can easily be accessed by clicking on their titles on the subject pages (also printed at the end of this Working Material). Part 1 of the CD-ROM covers the activities in the period 2003-2005 and part 2 presents a resource material full text CD-ROM on Managing Nuclear Knowledge issued in October 2003

  7. Environmental awareness -- An interactive multimedia CD-ROM

    Energy Technology Data Exchange (ETDEWEB)

    Huntelmann, A.; Petruk, M.W.

    1998-07-01

    As corporations move to new and innovative ways of structuring high-performance work teams, effective training is being recognized as a key to insuring success. Time and scheduling constraints tend to limit the effectiveness of traditional approaches to training. This has led Edmonton Power Inc. to explore the use of CD-ROM based multimedia as a means of delivering individualized instruction in an effective and timely manner. This session will demonstrate a multimedia CD-ROM based course on Environmental Awareness designed for workers in the electrical utilities industry. The objective of the course is to make workers aware of their roles and responsibilities with respect to their impact on the environment. This session will also describe the instructional design strategy underlying this approach to training and will present some preliminary findings with respect to the effectiveness of this approach. Individuals who are interested in improving the effectiveness of their environmental training program as well as individuals who are interested in understanding the strengths of multimedia CD-ROM based training will find this session useful and informative.

  8. CD-ROM for the PGAA-IAEA database

    International Nuclear Information System (INIS)

    Firestone, R.B.; Zerking, V.

    2007-01-01

    Both the database of prompt gamma rays from slow neutron capture for elemental analysis and the results of this CRP are available on the accompanying CD-ROM. The file index.html is the home page for the CD-ROM, and provides links to the following information: (a) The CRP - General information, papers and reports relevant to this CRP. (b) The PGAA-IAEA database viewer - An interactive program to display and search the PGAA database by isotope, energy or capture cross-section. (c) The Database of Prompt Gamma Rays from Slow Neutron Capture for Elemental Analysis - This report. (d) The PGAA database files - Adopted PGAA database and associated files in EXCEL, PDF and Text formats. The archival databases by Lone et al. and by Reedy and Frankle are also available. (e) The Evaluated Gamma-Ray Activation File (EGAF) - The adopted PGAA database in ENSDF format. Data can be viewed with the Isotope Explorer 2.2 ENSDF Viewer. (f) The PGAA database evaluation - ENSDF format versions of the adopted PGAA database, and the Budapest and ENSDF isotopic input files. Decay scheme balance and statistical analysis summaries are provided. (g) The Isotope Explorer 2.2 ENSDF viewer - Windows software for viewing the level scheme drawings and tables provided in ENSDF format. The complete ENSDF database is included, as of December 2002. The databases and viewers are discussed in greater detail in the following sections

  9. How To Use the SilverPlatter Software To Search the ERIC CD ROM.

    Science.gov (United States)

    Merrill, Paul F.

    This manual provides detailed instructions for using SilverPlatter software to search the ERIC CD ROM (Compact Disk Read Only Memory), a large bibliographic database relating to education which contains reference information on numerous journal articles from over 750 journals cited in the "Current Index to Journals in Education" (CIJE),…

  10. New Access Points to ERIC--CD-ROM Versions. ERIC Digest.

    Science.gov (United States)

    McLaughlin, Pamela W.

    This digest reviews three CD-ROM (compact disc-read only memory) versions of the ERIC (Educational Resources Information Center) database currently being delivered or tested and provides information for comparison. However, no attempt is made to recommend any one product. The advantages and disadvantages of the acquisition of CD-ROM databases are…

  11. Data on the environment. Accompanying brochure of the CD ROM; Daten zur Umwelt. Begleitbroschuere zur CD-ROM

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-07-15

    During the past 25 years, the Federal Environmental Office (UBA) has been publishing annual data on the environmental situation in Germany. This is the most recent publication; it contains data on climate protection, resources management, environment, health and quality of life, natural cycles and environmental media, and the economic importance of environmental protection. The CD-ROM contains data and facts on all of these subjects. It provides detailed and comprehensive information on the current condition of the environment in Germany, strategies and goals of environmental policy, books and other publications for further reading, and links. The CD-ROM also contains a system of key environmental indicators which illustrates successful activities and needs for action of environmental policy. Integrated internet access ensures access to current information on the internet. (orig.)

  12. A condensed review of the manageral aspects of CD-ROM network system

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Kwang

    2001-10-01

    This report discussed manageral aspects of CD-ROM Network system to reduce executing errors and to provide effective information services to users. The results of this study are follows. 1) Library has to decide the type fo cd-rom network system compatible to the library. 2) A way of acquiring of system purchasing budget is commom utility budgets and has to include system maintenance budget. 3) When decides a provider, it is needed to review price, maintenance ability, statistics s/w, anti-virus functions.4) System manager would be a one wide-range of knowledge about network, equipment, s/w and needs continuous education about system. 5) The system users are required to have more basic knowledge than general users other users, library has to provide various user educations and minute user manuals. 6) Purchasing of CD-ROM for network use is essential and cost-benefit analysis between on-line DB and cd-rom for one user are needed. 7) when constructing Local DB using CD-RM NETWORK SYSTEM, library give attention to copyrigths of the cd-rom. 8) To provide good services through the system, cross cooperation between library and related departments is required.

  13. Type 1 Diabetes in Children: A Passport to Knowledge. [CD-ROM].

    Science.gov (United States)

    2001

    This educational CD-ROM is designed to provide a working knowledge of diabetes and its effect on children. It is intended for parents, health care professionals, pharmacists, teachers, coaches, and child care providers. The CD-ROM examines issues related to diabetes management (food, insulin, monitoring, hypoglycemia, and illness); lifestyle; and…

  14. NODC Standard Product: NODC Taxonomic Code on CD-ROM (NODC Accession 0050418)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The content of the NODC Taxonomic Code, Version 8 CD-ROM (CD-ROM NODC-68) distributed by NODC is archived in this accession. Version 7 of the NODC Taxonomic Code...

  15. Development and Evaluation of a Multimedia CD-ROM for Exercise During Pregnancy and Postpartum

    Science.gov (United States)

    Hausenblas, Heather A.; Brewer, Britton W.; Van Raalte, Judy L.; Cook, Brian; Downs, Danielle Symons; Weis, Carol Ann; Nigg, Claudio; Cruz, Amelia

    2008-01-01

    Objective To meet the need for an interactive product on exercise during pregnancy and postpartum, we developed and evaluated a personally-tailored multimedia CD-ROM. Methods Pregnant and postpartum women, who were randomly assigned to either the experimental group (PregXercise™ CD-ROM) or the control group (CD-ROM with neutral content), navigated through the CD-ROM for 1 hour. Main outcomes were exercise self-efficacy and knowledge. Results In analyses of covariance, compared with the control group, the experimental group had significant increases in self-efficacy and knowledge. Conclusion The multimedia CD-ROM delivering information about exercise motivation, guidelines, and prescription was effective in improving exercise self-efficacy and knowledge. Practice Implications Our preliminary results illustrate that healthcare professionals and researchers may use interactive multimedia for improving exercise behavior and related outcomes with pregnant and postpartum women. PMID:18068940

  16. Design issues and caching strategies for CD-ROM-based multimedia storage

    Science.gov (United States)

    Shastri, Vijnan; Rajaraman, V.; Jamadagni, H. S.; Venkat-Rangan, P.; Sampath-Kumar, Srihari

    1996-03-01

    CD-ROMs have proliferated as a distribution media for desktop machines for a large variety of multimedia applications (targeted for a single-user environment) like encyclopedias, magazines and games. With CD-ROM capacities up to 3 GB being available in the near future, they will form an integral part of Video on Demand (VoD) servers to store full-length movies and multimedia. In the first section of this paper we look at issues related to the single- user desktop environment. Since these multimedia applications are highly interactive in nature, we take a pragmatic approach, and have made a detailed study of the multimedia application behavior in terms of the I/O request patterns generated to the CD-ROM subsystem by tracing these patterns. We discuss prefetch buffer design and seek time characteristics in the context of the analysis of these traces. We also propose an adaptive main-memory hosted cache that receives caching hints from the application to reduce the latency when the user moves from one node of the hyper graph to another. In the second section we look at the use of CD-ROM in a VoD server and discuss the problem of scheduling multiple request streams and buffer management in this scenario. We adapt the C-SCAN (Circular SCAN) algorithm to suit the CD-ROM drive characteristics and prove that it is optimal in terms of buffer size management. We provide computationally inexpensive relations by which this algorithm can be implemented. We then propose an admission control algorithm which admits new request streams without disrupting the continuity of playback of the previous request streams. The algorithm also supports operations such as fast forward and replay. Finally, we discuss the problem of optimal placement of MPEG streams on CD-ROMs in the third section.

  17. Reta'maxik Qatzij--Conociendo Nuestro Idioma (Knowing Our Language). [CD-ROM].

    Science.gov (United States)

    Academy for Educational Development, Washington, DC.

    This CD-ROM is part of an interactive and dynamic multimedia package of information and games for learning K'iche' and Ixil. This CD-ROM includes six books in electronic format with interactive exercises that support improved bilingual and intercultural education and teacher training, specifically in the languages of K'iche' and Ixil. Books…

  18. An x ray archive on your desk: The Einstein CD-ROM's

    Science.gov (United States)

    Prestwich, A.; Mcdowell, J.; Plummer, D.; Manning, K.; Garcia, M.

    1992-01-01

    Data from the Einstein Observatory imaging proportional counter (IPC) and high resolution imager (HRI) were released on several CD-ROM sets. The sets released so far include pointed IPC and HRI observations in both simple image and detailed photon event list format, as well as the IPC slew survey. With the data on these CD-ROMS's the user can perform spatial analysis (e.g., surface brightness distributions), spectral analysis (with the IPC event lists), and timing analysis (with the IPC and HRI event lists). The next CD-ROM set will contain IPC unscreened data, allowing the user to perform custom screening to recover, for instance, data during times of lost aspect data or high particle background rates.

  19. Pricing Strategies for CD-ROM Products.

    Science.gov (United States)

    Rowley, J. E.

    1994-01-01

    Pricing strategies for subscriptions and licenses for CD-ROMs are different for single users and networks. The basic components of pricing strategies are charges for subscription, connect line, display/print, telecommunication, session rate, special commands, and special services. Highlights selected supplier pricing strategies for single users…

  20. CD-ROM technology at the EROS data center

    Science.gov (United States)

    Madigan, Michael E.; Weinheimer, Mary C.

    1993-01-01

    The vast amount of digital spatial data often required by a single user has created a demand for media alternatives to 1/2" magnetic tape. One such medium that has been recently adopted at the U.S. Geological Survey's EROS Data Center is the compact disc (CD). CD's are a versatile, dynamic, and low-cost method for providing a variety of data on a single media device and are compatible with various computer platforms. CD drives are available for personal computers, UNIX workstations, and mainframe systems, either directly connected, or through a network. This medium furnishes a quick method of reproducing and distributing large amounts of data on a single CD. Several data sets are already available on CD's, including collections of historical Landsat multispectral scanner data and biweekly composites of Advanced Very High Resolution Radiometer data for the conterminous United States. The EROS Data Center intends to provide even more data sets on CD's. Plans include specific data sets on a customized disc to fulfill individual requests, and mass production of unique data sets for large-scale distribution. Requests for a single compact disc-read only memory (CD-ROM) containing a large volume of data either for archiving or for one-time distribution can be addressed with a CD-write once (CD-WO) unit. Mass production and large-scale distribution will require CD-ROM replication and mastering.

  1. Networking CD-ROMs: The Decision Maker's Guide to Local Area Network Solutions.

    Science.gov (United States)

    Elshami, Ahmed M.

    In an era when patrons want access to CD-ROM resources but few libraries can afford to buy multiple copies, CD-ROM local area networks (LANs) are emerging as a cost-effective way to provide shared access. To help librarians make informed decisions, this manual offers information on: (1) the basics of LANs, a "local area network primer";…

  2. The Basic Economics of CD-ROM Pricing.

    Science.gov (United States)

    Erkkila, John E.

    1991-01-01

    This explanation of how the basic economic model of pricing applies to the CD-ROM industry considers the supply and demand sides of the market and compares three distinct pricing strategies: (1) pricing to maximize profits; (2) average cost pricing; and (3) marginal cost pricing. (EAM)

  3. Ionospheric data available on CD-ROM and on NDADS

    International Nuclear Information System (INIS)

    Bilitza, D.

    1996-01-01

    Information is provided on two CD-ROMs (for PCs) with ionospheric data: the ionosonde CD issued by NGDC/WDC-A-STP/NOAA/Boulder and the Atmosphere Explorer CD produced by NSSDC/WDC-A-R and S/NASA/Greenbelt. We also briefly describe the ionospheric/thermospheric data available through NSSDC's automated mail retrieval system (NDADS) and explain the procedure for obtaining NDADS data. (author). 3 figs

  4. Review of Cornaline de l'Inde/Carnelian in India CD-Rom.

    Directory of Open Access Journals (Sweden)

    Peter Grave

    2002-10-01

    Full Text Available The CD-Rom format has been around for some time now with CD-Rom readers a standard fitting on even the most basic PC. The strength of this technology is that it enables large amounts of data to be stored (650-700 MB on a reliable, portable and economical medium. The character of data stored is virtually only dependant on developments in the hardware and software used to generate and manage datasets, whether numeric arrays, databases, digital imagery or multimedia. These features have made it a popular mode for a diverse range of interactive educational, reference and entertainment software. As a medium that can hold thousand of 'pages' of text, spreadsheets, colour images, animations and digital movies, CD-Rom technology also offers obvious benefits for the delivery of the diversity of data produced by archaeological research. It is surprising then that projects such as the bilingual Cornaline de l'Inde/Carnelian in India are few and far between.

  5. Studi Korelasi Motivasi Pengguna Dengan Pemanfaatan Koleksi CD-ROM Di UPT Pusat Perpustakaan UII Yogyakarta (Study on Correlation Between The Motivation of Users and The Use of CD-ROM Collection At The Main Library of Indonesia Islamic University of Yogyakarta

    Directory of Open Access Journals (Sweden)

    Keni Hesti Handayani

    2015-12-01

    Full Text Available The research addresses three main issues: student motivation of Indonesia Islamic University of Yogyakarta, the use of CD-ROM collection at the main library of Indonesia Islamic University of Yogyakarta, and the correlation between student motivation and the use of CD-ROM collection at the library. The study uses a field research. The sample is accidental sampling which involves students using the collection of CD-ROM at the library. In the term of data collection, the writer uses some techniques those of which are documentation, observation, interview and questionnaire. The result of the research shows that, there are correlation between the motivation and the use of CD-ROM collection at the main library of Indonesia Islamic University of Yogyakarta. The research is hoped to contribute to the improvement of services of CD-ROM collection at library in particular and to the development of through collection at the library. Keyword: user motivation, the use of CD-ROM collection

  6. The systems prioritization method (SPM) CD-ROM demonstration for Waste Management '96

    International Nuclear Information System (INIS)

    Harris, C.L.; Boak, D.M.; Prindle, N.H.; Beyeler, W.

    1996-01-01

    In March 1994, the Department of Energy Carlsbad Area Office (DOE/CAO) implemented a performance-based planning method to assist in prioritization within the Waste Isolation Pilot Plant (WIPP). Probabilistic performance calculations were required for the Systems Prioritization Method (SPM) and roughly 46,700 combinations of activities were analyzed, generating a large volume of information to be documented, analyzed, and communicated. A self-contained information management system consisting of a relational database on a 600-megabyte CD-ROM was built to meet this need. The CD-ROM was used to store performance assessment results, data analysis and visualization tools, information about the activities, electronic copies of 40 ILFR 191 and 40 CFR 268, technical reference papers, and the final SPM report. Copies of the CD-ROM were distributed to interested members of the public, WIPP participants, and the Environmental Protection Agency (EPA)

  7. Use of CD-Rom databases by staff and students in the University of ...

    African Journals Online (AJOL)

    The focus of this study is the use of CD-ROM databases by staff and students in the university of Jos library. This is of interest as CD-ROM database services is in consonant with the vision of providing excellent and effective information services to all staff and students of university of Jos. The study was guided by six ...

  8. Public census data on CD-ROM at Lawrence Berkeley Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Merrill, D.W.

    1992-07-02

    In connection with the Comprehensive Epidemiologic Data Resource (CEDR) and Populations at Risk to Environmental Pollution (PAREP) projects, of the Information and Computing Sciences Division (ICSD) at Lawrence Berkeley Laboratory (LBL), are using public socioeconomic and geographic data files which are available to CEDR and PAREP collaborators via LBL's computing network. At this time 67 CD-ROM diskettes (approximately 35 gigabytes) are on line via the Unix file server cedrcd.lbl.gov. Most of the files are from the US Bureau of the Census, and most pertain to the 1990 Census of Population and Housing. This paper contains a list of the CD-ROMs available.

  9. Dea Computrix - another deity for the Roman Pantheon? Journeys in the Roman Empire CD-Rom

    Directory of Open Access Journals (Sweden)

    T. Sam N. Moorhead

    2002-08-01

    Full Text Available This article outlines a personal view on the content and production of a CD-Rom on the Roman world produced by The British Museum, Channel 4, Verulamium Museum and Braunarts: Journeys in the Roman Empire. I discuss some of the benefits of and problems with multimedia production and outline feedback from various evaluation projects of the CD-Rom. I also briefly discuss the future of CD-Roms in the face of a rapidly expanding internet with reference to other multimedia projects at The British Museum.

  10. Utilizing the Evaluation Process in CD-ROM Development.

    Science.gov (United States)

    Crews, Tena B.; Chalupa, Marilyn R.

    1999-01-01

    While a CD-ROM on network topologies was being developed, it was evaluated formatively by 14 office systems teachers and summatively by 23 students using it in class. Improvements in ease of use, performance, and the accuracy and clarity of content were made. (SK)

  11. The Virtual Man Project's CD-ROM "Voice Assessment: Speech-Language Pathology and Audiology & Medicine", Vol.1

    Directory of Open Access Journals (Sweden)

    Millena Maria Ramalho Matta Vieira

    2009-01-01

    Full Text Available The CD-ROM "Voice Assessment: Speech-Language Pathology and Audiology & Medicine" was developed as a teaching tool for people interested in the production of the spoken or sung human voice. Its content comprises several subjects concerning the anatomy and physiology of spoken and sung voice. A careful assessment becomes necessary in order to ensure the effectiveness of teaching and learning educational materials, whether related to education or health, within the proposal of education mediated by technology. OBJECTIVE: This study aimed to evaluate the efficacy of the Virtual Man Project's CD-ROM "Voice Assessment: Speech-Language Pathology and Audiology & Medicine", as a self-learning material, in two different populations: Speech-Language Pathology and Audiology students and Lyrical Singing students. The participants were instructed to study the CD-ROM during 1 month and answer two questionnaires: one before and another one after studying the CD-ROM. The quantitative results were compared statistically by the Student's t-test at a significance level of 5%. RESULTS: Seventeen out of the 28 students who completed the study, were Speech-Language Pathology and Audiology students, while 11 were Lyrical Singing students (dropout rate of 44%. Comparison of the answers to the questionnaires before and after studying the CD-ROM showed a statistically significant increase of the scores for the questionnaire applied after studying the CD-ROM for both Speech-Language Pathology and Audiology and Lyrical Singing students, with p<0.001 and p<0.004, respectively. There was also a statistically significant difference in all topics of this questionnaire for both groups of students. CONCLUSION: The results concerning the evaluation of the Speech-Language Pathology and Audiology and Lyrical Singing students' knowledge before and after learning from the CD-ROM allowed concluding that the participants made significant improvement in their knowledge of the proposed

  12. Public census data on CD-ROM at Lawrence Berkeley Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Merrill, D.W.

    1993-01-16

    The Comprehensive Epidemiologic Data Resource (CEDR) and Populations at Risk to Environmental Pollution (PAREP) projects, of the Information and Computing Sciences Division (ICSD) at Lawrence Berkeley Laboratory (LBL), are using public socioeconomic and geographic data files which are available to CEDR and PAREP collaborators via LBL's computing network. At this time 72 CD-ROM diskettes (approximately 37 gigabytes) are on line via the Unix file server cedrcd.lbl.gov''. Most of the files are from the US Bureau of the Census, and many of these pertain to the 1990 Census of Population and Housing. All the CD-ROM diskettes contain documentation in the form of ASCII text files. In addition, printed documentation for most files is available for inspection at University of California Data and Technical Assistance (UC DATA), tel. (510) 642-6571, or the UC Documents Library, tel. (510) 642-2569, both located on the UC Berkeley Campus. Many of the CD-ROM diskettes distributed by the Census Bureau contain software for PC compatible computers, for easily accessing the data. Shared access to the data is maintained through a collaboration among the CEDR and PAREP projects at LBL, and UC DATA, and the UC Documents Library. LBL is grateful to UC DATA and the UC Documents Library for the use of their CD-ROM diskettes. Shared access to LBL facilities may be restricted in the future if costs become prohibitive. Via the Sun Network File System (NFS), these data can be exported to Internet computers for direct access by the user's application program(s). Due to the size of the files, this access method is preferred over File Transfer Protocol (FTP) access. Please contact Deane Merrill (dwmerrill lbl.gov) if you wish to make use of the data.

  13. CD roms and multimedia projector as complimentary educational ...

    African Journals Online (AJOL)

    This paper examines the potentials of utilizing Compact Disk Read Only Memory (CD-ROM) and the multimedia projector as complimentary educational technology for teaching music in colleges of education in Nigeria. While recognizing the problem of ineffective methods of teaching in Nigeria's educational system, the ...

  14. Public census data on CD-ROM at Lawrence Berkeley Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Merrill, D.W.

    1992-10-01

    The Comprehensive Epidemiologic Data Resource (CEDR) and Populations at Risk to Environmental Pollution (PAREP) projects, of the Information and Computing Sciences Division (ICSD) at Lawrence Berkeley Laboratory (LBL), are using public socio-economic and geographic data files which are available to CEDR and PAREP collaborators via LBL's computing network. At this time 70 CD-ROM diskettes (approximately 36 gigabytes) are on line via the Unix file server cedrcd. lbl. gov. Most of the files are from the US Bureau of the Census, and most pertain to the 1990 Census of Population and Housing. All the CD-ROM diskettes contain documentation in the form of ASCII text files. Printed documentation for most files is available for inspection at University of California Data and Technical Assistance (UC DATA), or the UC Documents Library. Many of the CD-ROM diskettes distributed by the Census Bureau contain software for PC compatible computers, for easily accessing the data. Shared access to the data is maintained through a collaboration among the CEDR and PAREP projects at LBL, and UC DATA, and the UC Documents Library. Via the Sun Network File System (NFS), these data can be exported to Internet computers for direct access by the user's application program(s).

  15. Public census data on CD-ROM at Lawrence Berkeley Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Merrill, D.W.

    1992-10-01

    The Comprehensive Epidemiologic Data Resource (CEDR) and Populations at Risk to Environmental Pollution (PAREP) projects, of the Information and Computing Sciences Division (ICSD) at Lawrence Berkeley Laboratory (LBL), are using public socio-economic and geographic data files which are available to CEDR and PAREP collaborators via LBL`s computing network. At this time 70 CD-ROM diskettes (approximately 36 gigabytes) are on line via the Unix file server cedrcd. lbl. gov. Most of the files are from the US Bureau of the Census, and most pertain to the 1990 Census of Population and Housing. All the CD-ROM diskettes contain documentation in the form of ASCII text files. Printed documentation for most files is available for inspection at University of California Data and Technical Assistance (UC DATA), or the UC Documents Library. Many of the CD-ROM diskettes distributed by the Census Bureau contain software for PC compatible computers, for easily accessing the data. Shared access to the data is maintained through a collaboration among the CEDR and PAREP projects at LBL, and UC DATA, and the UC Documents Library. Via the Sun Network File System (NFS), these data can be exported to Internet computers for direct access by the user`s application program(s).

  16. Conserving Earth's Biodiversity. [CD-ROM and] Instructor's Manual.

    Science.gov (United States)

    2000

    This CD-ROM is designed as an interactive learning tool to support teaching in highly interdisciplinary fields such as conservation of biodiversity. Topics introduced in the software include the impact of humans on natural landscapes, threats to biodiversity, methods and theories of conservation biology, environmental laws, and relevant economic…

  17. Cd-Rom and Access to Information

    OpenAIRE

    Chacón Alvarado, Lucía

    2011-01-01

    The scientific and technological advances in the world and its application in different areas of knowledge have developed a new electronic age.Computers and telecommunications have created a new scenario for libraries and information centers leading to further changes in the use of its collections and its services increased. Libraries and information centers must address these changes because users demand access to information quickly and efficiently.The CD-ROM is a new technology that has be...

  18. Effects of Using Human Patient Simulator (HPS versus a CD-ROM on Cognition and Critical Thinking

    Directory of Open Access Journals (Sweden)

    Don Johnson, PhD

    2008-01-01

    Full Text Available Background: Very little prospective randomized experimental research exists on the use of simulation as a teaching method, and no studies have compared the two strategies of using the HPS and a CD-ROM. In addition, no researchers have investigated the effects of simulation on various levels of cognition, specifically lower-level and higher-level cognition or critical thinking.Objectives: A prospective pretest-posttest experimental mixed design (within and between was used to determine if there were statistically significant differences in HPS and CD-ROM educational strategies in lower-level, higher-level cognition and critical thinking.Results: A repeated measures multivariate analysis of variance (RMANOVA with LSD post-hoc tests were used to analyze the data. There were no significant differences between the HPS and CD-ROM groups on lower-level cognition scores. The HPS group did significantly better than the CD-ROM group on higher-level cognition and critical thinking scores.Conclusion: This study demonstrated that the choice of teaching strategies for lower-level cognition does not make a statistically significant difference in outcome. However, the HPS is superior to using CD-ROM and should be considered as the choice in teaching.

  19. OCONUS Compliance Assessment Protocols - Qatar (Army Version) (CD-ROM)

    National Research Council Canada - National Science Library

    Krooks, David A

    2004-01-01

    ...: 1 CD-ROM; 4 3/4 in.; 578 KB. ABSTRACT: This environmental compliance assessment manual is based on the Final Governing Standards for Environmental Security of United States Forces in the State of Qatar, 21 May 1999, and the Overseas...

  20. CD ROM 'Natural heritage of Slovakia'

    International Nuclear Information System (INIS)

    Uradnikova, B.

    2005-01-01

    Centre of Environmental Education Geopark ('Centre') applied environmental education into school and out-of-school institutions. The 'Centre' is working in the fields: environmental education, eco-tourism development, presentation of the cultural landscape and world heritage. The CD ROM 'Natural heritage of Slovakia' was created with aim enhancement of environmental awareness, pedagogy, education and development of eco-tourism on the Slovakia. It abets general review about environment, its components, legislative, history and the present day of nature and landscape protection

  1. A Look at Dialog's First CD-ROM Product.

    Science.gov (United States)

    Duggan, Mary Kay

    1987-01-01

    Discusses reasons for selecting ERIC with the Dialog OnDisc software for training information professionals in online searching at the University of California, Berkeley, and analyzes some of the features of the CD-ROM software. Pros and cons of online and OnDisc access are summarized, and three references are listed. (Author/MES)

  2. Qualitative evaluation of a colorectal cancer education CD-ROM for Community Health Aides/practitioners in Alaska.

    Science.gov (United States)

    Cueva, Melany; Dignan, Mark; Lanier, Anne; Kuhnley, Regina

    2014-12-01

    Colorectal cancer (CRC) is an important contributor to the cancer burden among Alaska Native people. CRC is the leading incident cancer and the second leading cause of cancer mortality among Alaska Native people. Completing recommended CRC screening procedures has the potential to reduce both CRC incidence and mortality. "Taking Action Colorectal Health," a multidimensional audiovisual, interactive CD-ROM, incorporates adult education learning principles to provide Alaska's Community Health Aides/Practitioners with timely, medically accurate, and culturally relevant CRC place-based education. Providing this resource on CD-ROM empowers learning within communities and places where people live or choose to learn. The dynamic process of developing, implementing, and evaluating this CRC CD-ROM was informed by a sociocultural approach to share health messages. Within this approach, cultural values, beliefs, and behaviors are affirmed as a place of wisdom and resilience and built upon to provide context and meaning for health messaging. Alaska Native values that honor family, relationships, the land, storytelling, and humor were included in CD-ROM content. Between January and May 2012, 20 interviews were conducted with individuals who had used the CD-ROM. Four categorical themes emerged from analysis of interview transcripts: likeability, utilization, helpfulness, and behavior change. As a result of self-paced learning through stories, movies, and interactive games, respondents reported healthy behavior changes they were making for themselves, with their families and in their patient care practices. This CD-ROM is a culturally based practical course that increased knowledge and activities around colorectal cancer screening by Community Health Aides/Practitioners in Alaska.

  3. Lab Manual & Resources for Materials Science, Engineering and Technology on CD-Rom

    Science.gov (United States)

    Jacobs, James A.; McKenney, Alfred E.

    2001-01-01

    The National Educators' Workshop (NEW:Update) series of workshops has been in existence since 1986. These annual workshops focus on technical updates and laboratory experiments for materials science, engineering and technology, involving new and traditional content in the field. Scores of educators and industrial and national laboratory personnel have contributed many useful experiments and demonstrations which were then published as NASA Conference Proceedings. This "out poring of riches" creates an ever-expanding shelf of valuable teaching tools for college, university, community college and advanced high school instruction. Now, more than 400 experiments and demonstrations, representing the first thirteen years of NEW:Updates have been selected and published on a CD-ROM, through the collaboration of this national network of materials educators, engineers, and scientists. The CD-ROM examined in this document utilizes the popular Adobe Acrobat Reader format and operates on most popular computer platforms. This presentation provides an overview of the second edition of Experiments in Materials Science, Engineering and Technology (EMSET2) CD-ROM, ISBN 0-13-030534-0.

  4. The Market Place: An Internal View of the Future of CD-ROM--The Perspective of the H. W. Wilson Company.

    Science.gov (United States)

    Miller, Frank W.; Loeding, Deborah Voigt

    1989-01-01

    Discussion of technological developments in library reference services focuses on contributions of the H. W. Wilson Company and highlights CD-ROM technology. Topics discussed include online access; menu-driven systems; CD-ROM hardware and software concerns; user response to CD-ROM; quality control of databases; pricing considerations; and future…

  5. The Writing Process for "Edutaining" CD-ROM Adventures.

    Science.gov (United States)

    Mountain, Lee

    2000-01-01

    Describes a CD-ROM adventure story written by the author to educate her students about the word relationships of synonyms and antonyms. Discusses how this interactive medium put a different twist on each of the stages of the writing process itself. Relates how two students enthusiastically used the program, and were inspired to write one of their…

  6. Multimedia CD-Rom on hydrogen and fuel cells. 2. rev. ed.; Die Multimedia CD-Rom zum Thema Wasserstoff und Brennstoffzellen

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    2007-07-01

    This CD-Rom contains well-presented information with informative illustrations, as well as a large download section with publications, reports, and presentations in.pdf form for in-depth studies. There is also a list of links to selected websites, with short explanations. [German] Die CD zum Thema ''Wasserstoff und Brennstoffzellen'' bietet sowohl gut gegliederte Informationen mit anschaulichen Bildern fuer die Lektuere am Monitor als auch eine grosse Download-Rubrik, in der zahlreiche Publikationen, Fachberichte, Praesentationen als PDF-Dateien abgelegt sind und fuers Studium bereitstehen. Ausserdem gibt es ein Link-Verzeichnis mit Verweisen und Erlaeuterungen zu ausgewaehlten Internet-Seiten.

  7. Land and Marine Gravity Data on CD-ROM - 1999 Edition

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Land and Marine Gravity 1999 Edition 2-volume CD-ROM set contains observed and derived land and marine gravity data contributed by many national and...

  8. Nanotechnology Aerospace Applications (Applications aerospatiales de la nanotechnologie) (CD-ROM)

    National Research Council Canada - National Science Library

    2007-01-01

    ...: 1 CD-ROM; 4 3/4 in.; 116 MB. ABSTRACT: The Educational Notes contain the abstracts and the lecture material of ten presentations, which provide a general introduction into nanotechnologies with selected topics, such as nanotechnology...

  9. Nanotechnology Aerospace Applications (Applications aerospatiales de la nanotechnologie) (CD-ROM)

    National Research Council Canada - National Science Library

    2005-01-01

    ...: 1 CD-ROM; 4 3/4 in.; 59.1 MB. ABSTRACT: The Educational Notes contain the abstracts and the lecture material of ten presentations, which provide a general introduction into nanotechnologies with selected topics, such as nanotechnology...

  10. Management of CD-ROM Resources in Nigeria Academic Libraries ...

    African Journals Online (AJOL)

    The study is on management of CD-ROM resources in Nigerian academic libraries with reference to Federal Polytechnic Nekede Library, Owerri. A descriptive survey method was adopted random sampling technique was used in selecting twenty five (25) staff from the library under study. The questionnaire was the major ...

  11. Stretching & Flexibility: An Interactive Encyclopedia of Stretching. [CD-ROM].

    Science.gov (United States)

    2002

    This CD-ROM offers 140 different stretches in full-motion video sequences. It focuses on the proper techniques for overall physical fitness, injury prevention and rehabilitation, and 23 different sports (e.g., golf, running, soccer, skiing, climbing, football, and baseball). Topics include stretching for sports; stretching awareness and education…

  12. Guide Structures in CD-ROM Dic- tionaries, with Specific Reference ...

    African Journals Online (AJOL)

    Not all the search options in CD-ROM dictionaries necessarily maintain the boundaries ... In this article all derivatives of lase are highlighted in the microstructure, ... searches frustrates the user and should be addressed in future editions of the.

  13. Public census data on CD-ROM at Lawrence Berkeley Laboratory. Revision 4

    Energy Technology Data Exchange (ETDEWEB)

    Merrill, D.W.

    1993-03-12

    The Comprehensive Epidemiologic Data Resource (CEDR) and Populations at Risk to Environmental Pollution (PAREP) projects, of the Information and Computing sciences Division (ICSD) at Lawrence Berkeley Laboratory (LBL), are using public socioeconomic and geographic data files which are available to CEDR and PAREP collaborators via LBL`s computing network. At this time 89 CD-ROM diskettes (approximately 45 gigabytes) are on line via the Unix file server cedrcd.lbl.gov. Most of the files are from the US Bureau of the Census, and many of these pertain to the 1990 Census of Population and Housing. All the CD-ROM diskettes contain documentation in the form of ASCII text files. In addition, printed documentation for most files is available for inspection at University of California Data and Technical Assistance (UC DATA), tel. (510) 642-6571, or the UC Documents Library, tel. (510) 642-2569, both located on the UC Berkeley Campus. Many of the CD-ROM diskettes distributed by the Census Bureau contain software for PC compatible computers, for easily accessing the data. Shared access to the data is maintained through a collaboration among the CEDR and PAREP projects at LBL, and UC DATA, and the UC Documents Library. LBL is grateful to UC DATA and the UC Documents Library for the use of their CD-ROM diskettes. Shared access to LBL facilities may be restricted in the future if costs become prohibitive. Via the Sun Network File System (NFS), these data can be exported to Internet computers for direct access by the user`s application program(s). Due to the size of the files, this access method is preferred over File Transfer Protocol (FTP) access.

  14. Public census data on CD-ROM at Lawrence Berkeley Laboratory. Revision 1

    Energy Technology Data Exchange (ETDEWEB)

    Merrill, D.W.

    1992-07-02

    In connection with the Comprehensive Epidemiologic Data Resource (CEDR) and Populations at Risk to Environmental Pollution (PAREP) projects, of the Information and Computing Sciences Division (ICSD) at Lawrence Berkeley Laboratory (LBL), are using public socioeconomic and geographic data files which are available to CEDR and PAREP collaborators via LBL`s computing network. At this time 67 CD-ROM diskettes (approximately 35 gigabytes) are on line via the Unix file server cedrcd.lbl.gov. Most of the files are from the US Bureau of the Census, and most pertain to the 1990 Census of Population and Housing. This paper contains a list of the CD-ROMs available.

  15. Effects of using simulation versus CD-ROM in the performance of ultrasound-guided regional anesthesia.

    Science.gov (United States)

    Gasko, John; Johnson, Arthur; Sherner, John; Craig, John; Gegel, Brian; Burgert, James; Sama, Samuel; Franzen, Thomas

    2012-08-01

    The purpose of this study was to determine which method of teaching, CD-ROM, simulation, or a combination of both, was more effective in increasing the performance of ultrasound-guided regional anesthesia. No studies have investigated these methods. The framework for this study was critical thinking. The study was a prospective, mixed (between and within) subjects, experimental design. The sample consisted of 29 student registered nurse anesthetists randomly assigned to 1 of 3 groups: CD-ROM (n = 11), simulation (n = 11), and combination (n = 7). All groups were evaluated by the use of cadavers before and 2 months after the intervention using a valid and reliable instrument of performance. A repeated-measures analysis of variance indicated that the combination was significantly better than the CD-ROM and simulation (P teaching ultrasound-guided regional anesthesia techniques.

  16. Reservoir and civil engineering geophysics (CD-Rom); Geophysique de gisement et de genie civil (CD-Rom)

    Energy Technology Data Exchange (ETDEWEB)

    Mari, J.L.; Chapellier, D.

    1999-07-01

    This CD-Rom is a pedagogical tool developed from the book 'field and civil engineering geophysics' (Technip ed., 1998). It presents the geophysical methods (surface and well geophysical surveys, radar surveys and well logging) and their application in the study of oil fields and also in civil engineering. Several cartoons illustrate the principle of methods, their domain of use and their limitations. It covers the following topics: surface seismic surveys (waves propagation, equipments, reflexion and refraction seismic surveys, surface waves); well seismic surveys (operation, data processing, imaging); well logging (acoustic, nuclear,electrical and others, methods of interpretation); radar surveys (principle, surface, wells, possibilities and limitations). (J.S.)

  17. Public census data on CD-ROM at Lawrence Berkeley Laboratory. Revision 3

    Energy Technology Data Exchange (ETDEWEB)

    Merrill, D.W.

    1993-01-16

    The Comprehensive Epidemiologic Data Resource (CEDR) and Populations at Risk to Environmental Pollution (PAREP) projects, of the Information and Computing Sciences Division (ICSD) at Lawrence Berkeley Laboratory (LBL), are using public socioeconomic and geographic data files which are available to CEDR and PAREP collaborators via LBL`s computing network. At this time 72 CD-ROM diskettes (approximately 37 gigabytes) are on line via the Unix file server ``cedrcd.lbl.gov``. Most of the files are from the US Bureau of the Census, and many of these pertain to the 1990 Census of Population and Housing. All the CD-ROM diskettes contain documentation in the form of ASCII text files. In addition, printed documentation for most files is available for inspection at University of California Data and Technical Assistance (UC DATA), tel. (510) 642-6571, or the UC Documents Library, tel. (510) 642-2569, both located on the UC Berkeley Campus. Many of the CD-ROM diskettes distributed by the Census Bureau contain software for PC compatible computers, for easily accessing the data. Shared access to the data is maintained through a collaboration among the CEDR and PAREP projects at LBL, and UC DATA, and the UC Documents Library. LBL is grateful to UC DATA and the UC Documents Library for the use of their CD-ROM diskettes. Shared access to LBL facilities may be restricted in the future if costs become prohibitive. Via the Sun Network File System (NFS), these data can be exported to Internet computers for direct access by the user`s application program(s). Due to the size of the files, this access method is preferred over File Transfer Protocol (FTP) access. Please contact Deane Merrill (dwmerrill@lbl.gov) if you wish to make use of the data.

  18. Operating Experience with Nuclear Power Stations in Member States. 2016 Edition (CD-ROM)

    International Nuclear Information System (INIS)

    2016-06-01

    This CD-ROM contains the 47th edition of the IAEA’s series of annual reports on operating experience with nuclear power plants in Member States. It is a direct output from the IAEA’s Power Reactor Information System (PRIS) and contains information on electricity production and overall performance of individual plants during 2015. In addition to annual information, the report contains a historical summary of performance during the lifetime of individual plants and figures illustrating worldwide performance of the nuclear industry. The CD-ROM contains also an overview of design characteristics and dashboards of all operating nuclear power plants worldwide

  19. OCONUS Compliance Assessment Protocols (OCAP) - Saudi Arabia (Army Version) (CD-ROM)

    National Research Council Canada - National Science Library

    Krooks, David A; Schell, Donna J

    2004-01-01

    ...: 1 CD-ROM; 4 3/4 in.; 670 KB. ABSTRACT: This environmental compliance assessment manual is based on the Final Governing Standards for Environmental Security by United States Forces in the Kingdom of Saudi Arabia (FGS-SA...

  20. Natural Tasking of Robots Based on Human Interaction Cues (CD-ROM)

    National Research Council Canada - National Science Library

    Brooks, Rodney A

    2005-01-01

    ...: 1 CD-ROM; 4 3/4 in.; 207 MB. ABSTRACT: We proposed developing the perceptual and intellectual abilities of robots so that in the field, war-fighters can interact with them in the same natural ways as they do with their human cohorts...

  1. Evaluation of the acceptability of a CD-Rom as a health promotion tool for Inuit in Ottawa.

    Science.gov (United States)

    McShane, Kelly E; Smylie, Janet K; Hastings, Paul D; Prince, Conrad; Siedule, Connie

    2013-01-01

    There are few health promotion tools for urban Inuit, and there is a specific dearth of evaluations on such tools. The current study used a community-specific approach in the evaluation of a health promotion tool, based on an urban Inuit community's preferences of health knowledge sources and distribution strategies. In partnership with the Tungasuvvingat Inuit Family Health Team in Ottawa, a CD-Rom was developed featuring an Inuk Elder presenting prenatal health messages in both Inuktitut and English. Also, relevant evaluation materials were developed. Using a mixed methods approach, 40 participants completed interviews prior to viewing the CD-Rom and participated in a focus group at follow-up. Questionnaires were also completed pre- and post-viewing to assess changes between expectations and reactions in order to document acceptability. Significant increases were found on satisfaction, acceptability of medium and relevance of content ratings. Qualitative findings also included (a) interest, uncertainty and conditional interest prior to viewing; and (b) positive evaluations of the CD-Rom. This suggests that CD-Rom technology has the potential for health promotion for urban Inuit, and the community-specific evaluation approach yielded useful information.

  2. NODC Standard Product: World Ocean Circulation Experiment (WOCE) Global Data Resource (GDR), versions 1-3, on CD-ROM and DVD

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NODC produced twelve (12) CD-ROMs containing WOCE Version 1 project data in the summer of 1998. NODC produced fifteen (15) CD-ROMs containing WOCE Version 2 project...

  3. Planning and Preparation for CD-ROM Implementation: The Citadel Library.

    Science.gov (United States)

    Maynard, J. Edmund

    Management guidelines for library planning and a strategic planning program profile based on the literature were used in the planning process for implementing access to databases on CD-ROM at the Daniel Library of the Citadel, Military College of South Carolina. According to this model, the planning process would consist of five stages: (1)…

  4. Canister Design for Deep Borehole Disposal of Nuclear Waste (CD-ROM)

    National Research Council Canada - National Science Library

    Hoag, Christopher I

    2006-01-01

    ...: 1 CD-ROM; 4 3/4 in.; 28.7 MB. ABSTRACT: The objective of this thesis was to design a canister for the disposal of spent nuclear fuel and other high-level waste in deep borehole repositories using currently available and proven oil, gas...

  5. Marketing and Selling CD-ROM Products on the World-Wide Web.

    Science.gov (United States)

    Walker, Becki

    1995-01-01

    Describes three companies' approaches to marketing and selling CD-ROM products on the World Wide Web. Benefits include low overhead for Internet-based sales, allowance for creativity, and ability to let customers preview products online. Discusses advertising, information delivery, content, information services, and security. (AEF)

  6. Air Force Research Laboratorv Success Stories: A Review of 2004 (CD-ROM)

    National Research Council Canada - National Science Library

    2004-01-01

    ...). PHYSICAL DESCRIPTION: 1 CD-ROM; 4 3/4 in.; 43.5 MB. ABSTRACT: The Air Force Science and Technology Success Stories herein often represent the combined effort of several scientists and engineers working as a team...

  7. Energy-Smart Choices for Schools. An HVAC Comparison Tool. [CD-ROM].

    Science.gov (United States)

    Geothermal Heat Pump Consortium, Inc., Washington, DC.

    A CD ROM program provides comparison construction cost capabilities for heating, ventilation, and air conditioning (HVAC) systems in educational facilities. The program combines multiple types of systems with square footage data on low and high construction cost and school size to automatically calculate HVAC comparative construction costs. (GR)

  8. Operating Experience with Nuclear Power Stations in Member States in 2014. 2015 Edition (CD-ROM)

    International Nuclear Information System (INIS)

    2015-01-01

    This CD-ROM contains the 46th edition of the IAEA’s series of annual reports on operating experience with nuclear power plants in Member States. It is a direct output from the IAEA’s Power Reactor Information System (PRIS) and contains information on electricity production and overall performance of individual plants during 2014. In addition to annual information, the report contains a historical summary of performance during the lifetime of individual plants and figures illustrating worldwide performance of the nuclear industry. The CD-ROM contains also an overview of design characteristics and dashboards of all operating nuclear power plants worldwide

  9. Development and testing of a CD-ROM program for improving adolescent knowledge of inflammatory bowel disease.

    Science.gov (United States)

    Boamah, Lynelle M; Bohren, Janet R; Pentiuk, Scott; Baker, Raymond; Yi, Michael; Moyer, M Susan

    2010-05-01

    The aim of this study was to design a theory-based educational program for adolescents with inflammatory bowel disease (IBD) using an interactive multimedia CD-ROM and to test its effectiveness in improving knowledge in IBD. Curriculum-based instruction using educational theory and principles was designed for adolescents on an interactive multimedia CD-ROM. Twenty subjects completed summative evaluation of the CD-ROM measuring gain in knowledge about IBD immediately and 9 months after instruction. Subjects found the CD-ROM to be informative, appealing, and easy to use. The mean baseline score of the adolescents on the Crohn's and Colitis Knowledge questionnaire was 12.2 (standard deviation 5.14, range 3-24). After an average of 30 minutes of self-directed learning, adolescent subjects increased their posttest score to a mean of 19.8, a gain of 7.6 points over baseline (95% confidence interval 5.2-10.1, P < 0.0001). Knowledge of medications, disease complications, and gastrointestinal structure and function was gained and retained upon retesting at 9 months with a mean Crohn's and Colitis Knowledge questionnaire score of 17.5 (standard deviation 3.9, range 12-26), which was still an improvement over the mean pretest knowledge score of 12.2 (P < 0.001). Adolescents with IBD have low baseline knowledge about their disease. A rigorously developed interactive educational tool is now available for instructing adolescent patients about their IBD.

  10. CD-ROM training course in quality assurance in diagnostic imaging

    International Nuclear Information System (INIS)

    Khoury, H.J.; Machado, P.; Drexler, G.

    2001-01-01

    This paper discusses the CD-ROM elaborated to provide a continuous professional formation and a practical guidance on the implementation and operation of routine quality assurance (QA) programme for medical physicists, regulator authorities and for those personnel concerned with the daily provision of diagnostic radiology services. The CD-ROM contains topics on the basic concepts of QA in radiodiagnostic, and it also allows the user to visualise effects on the variation of technical parameters (tube potential (kV) and current (mA), filtration) in the quality of the image. This possibility will contribute to the better understanding of the phenomena associated with the quality of the image. Besides, the program contains the procedures for the execution of the tests of the equipment and the route of implantation of program of quality assurance. It is interactive with the user, it fills a gap in the medical physics area and it allows the student's continuous formation because it assists the beginner, with the basic concepts, and the professional, with the aid in the implantation of the program of QA. The presentation is in the Portuguese language. (author)

  11. 經由校園網路存取圖書館光碟資料庫之研究 Studies on Multiuser Access Library CD-ROM Database via Campus Network

    Directory of Open Access Journals (Sweden)

    Ruey-shun Chen

    1992-06-01

    Full Text Available 無Library CD-ROM with its enormous storage, retrieval capabilities and reasonable price. It has been gradually replacing some of its printed counterpart. But one of the greatest limitation on the use of stand-alone CD-ROM workstation is that only one user can access the CD-ROM database at a time. This paper is proposed a new method to solve this problem. The method use personal computer via standard network system Ethernet high speed fiber network FADDY and standard protocol TCP/IP can access library CD-ROM database and perform a practical CD-ROM campus network system. Its advantage reduce redundant CD-ROM purchase fee and reduce damage by handed in and out and allows multiuser to access the same CD-ROM disc simultaneously.

  12. Operating Experience with Nuclear Power Stations in Member States in 2013. 2014 Edition (CD-ROM)

    International Nuclear Information System (INIS)

    2014-07-01

    This CD-ROM contains the 45th edition of the IAEA's series of annual reports on operating experience with nuclear power plants in Member States. It is a direct output from the IAEA's Power Reactor Information System (PRIS) and contains information on electricity production and overall performance of individual plants during 2013. In addition to annual information, the report contains a historical summary of performance during the lifetime of individual plants and figures illustrating worldwide performance of the nuclear industry. The CD-ROM contains also an overview of design characteristics and dashboards (not included into the web version) of all operating nuclear power plants worldwide

  13. The New York Trade Publishers and CD-ROM: Where Are They Heading?

    Science.gov (United States)

    Newmark, Eileen

    1994-01-01

    Discusses the strategies top trade publishers, including Putnam New Media, Paramount Communications, Random House, Penguin USA, and Reader's Digest, are taking toward CD-ROM publishing. Strategies include purchasing electronic media companies; setting up an independent business; and building a new media business by integrating new efforts into the…

  14. Factors Affecting Pre-Service TESOL Teachers' Attitudes towards Using CD-ROM Dictionary

    Science.gov (United States)

    Issa, Jinan Hatem; Jamil, Hazri

    2011-01-01

    Rapid technological advances in communication technologies and computational power are altering the nature of knowledge, skills, talents and the know-how of individuals. A CD-ROM dictionary is an interesting and effective teaching tool, which captures pre-service teachers' interest and does much more than just translates especially with the…

  15. Guide Structures in CD-ROM Dictionaries, with Specific Reference to the EWED and the ELHAT

    Directory of Open Access Journals (Sweden)

    Philip Louw

    2011-10-01

    Full Text Available

    macro- and microstructural information. In order to evaluate the methods which lexicographers employ to improve dictionary accessibility, the concept of guide structures was introduced by Hausmann and Wiegand (1989. Since the appearance of that article, various academics have written articles and read papers on guide structures in print dictionaries, but few studies have focussed on the tremendous potential of guide structures in electronic dictionaries. In this article it will be shown that electronic dictionaries add dimensions to the implementation of guide structures not possible in print versions. The role of two of the guide structures in the transfer of infonnation in CD-ROM dictionaries will be discussed. The access and mediostructures of the Microsoft Encarta World English Dictionary and the Elektroniese Handwoordeboek van die Afrikaanse Taal will be analysed and critically evaluated to illustrate the advantages of electronic dictionaries over print dictionaries and the urgent need for metalexicographical discussion of this publication medium.

    Keywords: ACCESS STRUCTURE; ACTIVE CROSS-REFERENCES; CD-ROM DICTIONARY; DICTIONARY ACCESSIBILITY; ENCYCLOPAEDIC DICTIONARY; GUIDE STRUCTURES; INNER ACCESS STRUCTURE; INNER SEARCH PATH; INTERNET; MEDIOSTRUCTURE; MULTIMEDIA; OUTER ACCESS STRUCTURE; OUTER SEARCH PATH; PASSIVE CROSSREFERENCING; USER-FRIENDLINESS

    Opsomming: Gidsstrukture in CD-ROM-woordeboeke, met spesifieke verwysingna EWED en ELHA T. Die sukses van modeme woordeboeke hang grootliles af vandie toeganklikheid van hulle makro- en mikrostrukturele inligting. Hausmann en Wiegand (1989het die konsep van gidsstrukture ingevoer om die metodes te evalueer wat leksikograwe gebruikom woordeboektoeganklikheid Ie verbeter. Sedert hierdie artikel verskyn het, het verskeie akademic:i artikels gepubliseer en referate gelewer oor gidsstrukture in gedrukte woordeboeke, maarmin studies het gefokus op die geweldige potensiaal van

  16. Advanced grammar in use a self-study reference and practice book for advanced students of English : with answers and CD-ROM

    CERN Document Server

    Hewings, Martin

    2013-01-01

    An updated version of the highly successful Advanced Grammar in Use. This third edition, with answers and CD-ROM, is ideal for self-study. The book contains 100 units of grammar reference and practice materials, with illustrations in full colour and a user-friendly layout. It is ideal for learners preparing for the Cambridge Advanced, Proficiency or IELTS examinations, and is informed by the Cambridge International Corpus, which ensures the language is authentic and up-to-date. The CD-ROM includes 200 interactive exercises to reinforce the language learned in the book, plus customised tests and audio recordings to accompany the main exercises. Versions without answers and without the CD-ROM are available to purchase separately.

  17. Occupational Analysis Products: Space Systems Operations - AFSC 1C6X1 (CD-ROM)

    National Research Council Canada - National Science Library

    Boerstler, Robert E

    2004-01-01

    ...: 1 CD-ROM; 4 3/4 in.; 30.4 MB. SYSTEMS DETAIL NOTE: ABSTRACT: The Space Systems Operations career ladder was surveyed to obtain current task and equipment data for use in evaluating current training programs...

  18. Caspian Sea Energy: Oil, Politics and Development in the Caspian Sea Region (CD-ROM)

    National Research Council Canada - National Science Library

    Light, Chris

    2004-01-01

    ...: 1 CD-ROM; 4 3/4 in.; 5.0 MB. ABSTRACT: The purpose of this paper is to present the major issues impacting Caspian hydrocarbon development Specifically, a number of topics including the regions geography, history, governments, politics...

  19. Year 5 Pupils Reading an "Interactive Storybook" on CD-ROM: Losing the Plot?

    Science.gov (United States)

    Trushell, John; Burrell, Clare; Maitland, Amanda

    2001-01-01

    This study examined whether small groups of grade 5 students in a London primary school, without teacher supervision, progressed linearly through an interactive storybook on CD-ROM, and whether such diversions as cued animations affected pupil comprehension. Results showed students' recall of the storyline was poor. (Author/LRW)

  20. Setting Up CD-ROM Work Areas. Part I: Ergonomic Considerations, User Furniture, Location.

    Science.gov (United States)

    Vasi, John; LaGuardia, Cheryl

    1992-01-01

    The first of a two-part series on design of CD-ROM work areas in libraries discusses (1) space and location considerations; (2) ergonomics, including work surface, chairs, lighting, printers, other accessories, and security; and (3) other considerations, including staff assistance, reference tools, literature racks, and promotional materials. (MES)

  1. Helping Family Physicians Improve Their Cardiac Auscultation Skills with an Interactive CD-ROM.

    Science.gov (United States)

    Roy, Douglas; Sargeant, Joan; Gray, Jean; Hoyt, Brian; Allen, Michael; Fleming, Michael

    2002-01-01

    Physicians (n=42) studied cardiac auscultation using a 15-hour CD-ROM program. Nine months later, 21 who completed a posttest showed significant improvement in identifying heart sounds. CDs were valued for opportunities to review material at an individual pace. Lack of computer skills hindered use. (Contains 26 references.) (SK)

  2. Whole Language, Computers and CD-ROM Technology: A Kindergarten Unit on "Benjamin Bunny."

    Science.gov (United States)

    Balajthy, Ernest

    A kindergarten teacher, two preservice teachers, and a college consultant on educational computer technology designed and developed a 10-day whole-language integrated unit on the theme of Beatrix Potter's "Benjamin Bunny." The project was designed as a demonstration of the potential of integrating the CD-ROM-based version of…

  3. Occupational Analysis Products: Operations Management- AFSC 3E6X1 (CD-ROM)

    Science.gov (United States)

    computer laser optical disc (CD-ROM); 4 3/4 in.; 23.4 MB. SYSTEMS DETAIL NOTE: ABSTRACT: This is a report of an occupational survey of the Operations ... Management (AFSC 3E6X1, OSSN 2560, Feb 04) career ladder, conducted by the Occupational Analysis Flight, AFOMS. The OSR reports the findings of current

  4. Evaluation of the use of CD-ROM upload into the PACS or institutional web server

    NARCIS (Netherlands)

    van Ooijen, P. M. A.; Roosjen, R.; de Blecourt, M. J.; van Dam, R.; Broekema, A.; Oudkerk, M.

    2006-01-01

    Purpose: Patient data are increasingly distributed between hospitals using CD-ROMs instead of actual films. This introduces problems because different viewers from different vendors are provided, and sometimes viewers are unusable because local software installation is not allowed. In 2004, we

  5. DICOM storage into PACS of out-hospital CD-ROMs - a half year experience report

    NARCIS (Netherlands)

    van Ooijen, PMA; ten Bhomer, PJM; Blecourt, MJ; Roosjen, R; van Dam, R; Oudkerk, A; Lemke, HU; Inamura, K; Doi, K; Vannier, MW; Farman, AG

    2005-01-01

    With the advance of digitalization of radiology departments, the interchange of data between institutions is shifting towards shipment of CD-ROMs instead of physical film. Although this is a positive change in terms of costs, it also has its downsides. One of the main problems is how to integrate

  6. Genetics, mental illness, and complex disease: development and distribution of an interactive CD-ROM for genetic counselors. Final report for period 15 August 2000 - 31 December 2002

    Energy Technology Data Exchange (ETDEWEB)

    McInerney, Joseph D.

    2003-03-31

    "Genetics and Major Psychiatric Disorders: A Program for Genetic Counselors" provides an introduction to psychiatric genetics, with a focus on the genetics of common complex disease, for genetics professionals. The program is available as a CD-ROM and an online educational resource. The on-line version requires a direct internet connection. Each educational module begins with an interactive case study that raises significant issues addressed in each module. In addition, case studies provided throughout the educational materials support teaching of major concepts. Incorporated throughout the content are expert video clips, video clips from individuals affected by psychiatric illness, and optional "learn more" materials that offer greater depth about a particular topic. The structure of the CD-ROM permits self-navigation, but we have suggested a sequence that allows materials to build upon each other. At any point in the materials, users may pause and look up terms in the glossary or review the DSM-IV criteria for selected psychiatric disorders. A detailed site map is available for those who choose to self navigate through the content.

  7. Recovery of Data from the Narragansett Bay Project, 1985-1992: User's Manual and CD-ROM

    Science.gov (United States)

    Data from the 1985-1992 era of the Narragansett Bay Project, an estuary of the National Estuary Program, were recovered from numerous storage media, updated to modern software, and burned to CD-ROM. The data will be used by, among others, EPA researchers working on long-term tren...

  8. Exploiting the Potential of CD-ROM Databases: Staff Induction at the University of East Anglia.

    Science.gov (United States)

    Guillot, Marie-Noelle; Kenning, Marie-Madeleine

    1995-01-01

    Overviews a project exploring the possibility of using CD-ROM applications and the design of exploratory didactic materials to introduce academic staff to the field of computer-assisted instruction. The project heightened the staff's awareness of electronic resources and their potential as research, teaching, and learning aids, with particular…

  9. Flight Experiments for Hypersonic Vehicle Development (Experimentations envol pour le developpement d'un vehicule hypersonique) (CD-ROM)

    National Research Council Canada - National Science Library

    2007-01-01

    ...: 1 CD-ROM; 4 3/4 in.; 124 MB. ABSTRACT: This RTO-AVT/VKI Lecture Series brought together specialists from Europe, USA, and Russia to discuss flight experiments that pertain to the development of hypersonic vehicles...

  10. The Impact of Animation in CD-ROM Books on Students' Reading Behaviors and Comprehension.

    Science.gov (United States)

    Okolo, Cindy; Hayes, Renee

    This study evaluated the use of children's literature presented via one of three conditions: an adult reading a book to the child; the child reading a CD-ROM version of a book on the computer but without animation; and the child reading the book on the computer with high levels of animation. The study, in one primary grade classroom, involved 10…

  11. [Medical knowledge in immunological security of red blood cells transfusion in Tunisia: evaluation of a CD-ROM of auto-learning].

    Science.gov (United States)

    Ben Salah, N; El Borgi, W; Aounallah Skhiri, H; Ben Lakhal, F; Mouelhi, H; Zoueri, B; Gouider, E; Hafsia, R

    2013-09-01

    In Tunisia, red blood cells (RBC) transfusion joins in a statutory frame but remains subject to failures because of the misunderstanding of legislation and regulations. Our purpose is to estimate the knowledge of the medical staff in the immunological safety of RBC transfusion before and after reading an auto-education CD-ROM. It is a study of evaluation of an intervention. Eighty physicians participated to the study. The evaluation was done using an anonymous questionnaire, containing seven questions with multiple choices (QMC) relating to several items. The rate of good answers (RGA) calculated by questions and by items took into account the impact of the CD-ROM on the improvement of the answers after reading. The global average mark is 2.9/7. The RGA to questions varies from 22.5 % to 76.3%. All participants answered correctly to more than 50% of all items. Two answered correctly to all items. Among the participants, 31.3% answered to all "important" items, concerning ABO blood groups compatibility and ultimate bedside test. The rate of participation to the final evaluation was 83%. The impact of the CD-ROM was important and statistically significant. In the final evaluation, the global mark raised from 2.9 to 5.8/7, 31.5% (vs 2%) answered correctly all the questions and 95.5% (vs 31.3%) answered correctly all "important" items. This study revealed a misunderstanding of the doctors in immunological safety of RBC transfusions. Auto-teaching by CD-ROM was efficient. An improvement of the knowledge by continuous training is necessary in our country. Copyright © 2013 Elsevier Masson SAS. All rights reserved.

  12. Investigating the use of CD-Rom CBT for bulimia nervosa and binge eating disorder in an NHS adult outpatient eating disorders service.

    Science.gov (United States)

    Graham, Lisa; Walton, Mark

    2011-07-01

    Many patients who experience bulimia nervosa (BN) and binge eating disorder (BED) find it hard to access evidence-based treatments. Rates of failure to enter outpatient services following initial assessment are high, as are dropout rates from specialist outpatient eating disorders services. To offer CD-Rom CBT, a cognitive-behavioural multi-media supported self-help treatment, in a locality-based outpatient NHS Eating Disorders Service to patients who have binge eating disorder and bulimia nervosa. Patients referred to a catchment-based NHS outpatient eating disorders service who were assessed and had an eating disorder with a binge-eating component were offered CD-Rom based CBT (Overcoming Bulimia) whilst on the waiting list for individual CBT. Forty patients completed the 8 sessions and attended the evaluation appointment (13 had BN, 27 had BED). For both groups, there were significant improvements in well-being and functioning, as well as significant reductions in problems and risk. There was also a significant reduction on the "Bulimic Subscale" of the EDI. These results were comparable with the original study findings (Schmidt, Treasure and Williams, 2001). Dropouts from the CD-Rom reflected rates common to other EDS treatments suggesting that CD-Rom did not directly impact upon service dropout rates. Computer assisted CBT for Eating Disorders offers a promising, feasible and acceptable first step for patients who have bulimia nervosa or binge eating disorder and access treatment from specialist eating disorders services.

  13. Defense Information for All: DTIC 2007 Conference Held in Alexandria, Virginia on March 26-28, 2007 (CD-ROM)

    National Research Council Canada - National Science Library

    2007-01-01

    ...: 1 CD-ROM; 4 3/4 in.; 88.6 MB. ABSTRACT: The conference will bring together information professionals from the science, technology, research and development, and acquisition communities who create, disseminate and use DoD scientific...

  14. Analysis of Users' Searches of CD-ROM Databases in the National and University Library in Zagreb.

    Science.gov (United States)

    Jokic, Maja

    1997-01-01

    Investigates the search behavior of CD-ROM database users in Zagreb (Croatia) libraries: one group needed a minimum of technical assistance, and the other was completely independent. Highlights include the use of questionnaires and transaction log analysis and the need for end-user education. The questionnaire and definitions of search process…

  15. Car Builder: Design, Construct and Test Your Own Cars. School Version with Lesson Plans. [CD-ROM].

    Science.gov (United States)

    Highsmith, Joni Bitman

    Car Builder is a scientific CD-ROM-based simulation program that lets students design, construct, modify, test, and compare their own cars. Students can design sedans, four-wheel-drive vehicles, vans, sport cars, and hot rods. They may select for aerodynamics, power, and racing ability, or economic and fuel efficiency. It is a program that teaches…

  16. Adventures in Evaluation: Reviewing a CD-ROM Based Adventure Game Designed for Young People Recovering from Psychosis

    Science.gov (United States)

    Shrimpton, Bradley; Hurworth, Rosalind

    2005-01-01

    Recently the Centre for Program Evaluation (CPE) at the University of Melbourne was approached by a mental health agency to undertake the unique and challenging task of evaluating a prototype CD-ROM based adventure game designed for young people recovering from psychosis. This unusual and inventive game, titled Pogo's Pledge, used…

  17. Earth in Space: A CD-ROM Version for Pre-College Teachers

    Science.gov (United States)

    Pedigo, P.

    2003-12-01

    Earth in Space, a magazine about the Earth and space sciences for pre-college science teachers, was published by AGU between 1987 and 2001 (9 issues each year). The goal of Earth in Space was to make research at the frontiers of the geosciences accessible to teachers and students and engage them in thinking about scientific careers. Each issue contained two or three recent research articles, rewritten for a high school level audience from the original version published in peer-reviewed AGU journals, which were supplemented with short news items and biographic information about the authors. As part of a 2003 summer internship with AGU, sponsored by the AGU Committee on Education and Human Resources (CEHR) and the American Institute of Physics, this collection of Earth in Space magazines was converted into an easily accessible electronic resource for K-12 teachers and students. Every issue was scanned into a PDF file. The entire collection of articles was cataloged in a database indexed to key topic terms (e.g., volcanoes, global climate change, space weather). A front-page was designed in order to facilitate rapid access to articles concerning specific topics within the Earth and space sciences of particular interest to high school students. A compact CD-ROM version of this resource will be distributed to science teachers at future meetings of the National Science Teachers Association and will be made available through AGU's Outreach and Research Support program.

  18. The database system for the management of technical documentations of PWR fuel design project using CD-ROM

    International Nuclear Information System (INIS)

    Park, Bong Sik; Lee, Won Jae; Ryu, Jae Kwon; Jo, In Hang; Chang, Jong Hwa.

    1996-12-01

    In this report, the database system developed for the management of technical documentation of PWR fuel design project using CD-ROM (compact disk - read only memory) is described. The database system, KIRDOCM (KAERI Initial and Reload Fuel project technical documentation management), is developed and installed on PC using Visual Foxpro 3.0. Descriptions are focused on the user interface of the KIRDOCM. Introduction addresses the background and concept of the development. The main chapter describes the user requirements, the analysis of computing environment, the design of KIRDOCM, the implementation of the KIRDOCM, user's manual of KIRDOCM and the maintenance of the KIRDOCM for future improvement. The implementation of KIRDOCM system provides the efficiency in the management, maintenance and indexing of the technical documents. And, it is expected that KIRDOCM may be a good reference in applying Visual Foxpro for the development of information management system. (author). 2 tabs., 13 figs., 8 refs

  19. In company pre-intermediate student's book with CD-ROM

    CERN Document Server

    Clarke, Simon; Sharma, Pete

    2009-01-01

    In Company has established itself as the Business English course for professionals because of its immediate results through topic-based content, active skills, and real-world tasks that are instantly relevant to everyday business English development. In Company Second Edition builds on the success of the original but is now updated and improved with a host of new features. For extra online practice for your students, take a look at the new Second Edition In Company Practice Online solution. Accompanying the popular In Company series in British English, these online courses provide carefully designed resources to supplement the Student's Books at all levels. Units are clearly defined as Topic or Skills based NEW phrase banks with useful phrases for reference and revision 5 NEW case studies, within the Student's Book reflect real-life business scenarios Second Edition CD-ROM now includes a new interactive glossary and the class audio as a donwloadable MP3.

  20. Mars Navigator: An Interactive Multimedia Program about Mars, Aerospace Engineering, Astronomy, and the JPL Mars Missions. [CD-ROM

    Science.gov (United States)

    Gramoll, Kurt

    This CD-ROM introduces basic astronomy and aerospace engineering by examining the Jet Propulsion Laboratory's (JPL) Mars Pathfinder and Mars Global Surveyor missions to Mars. It contains numerous animations and narrations in addition to detailed graphics and text. Six interactive laboratories are included to help understand topics such as the…

  1. Computer Based Radiation Protection- A New Cd-Rom

    International Nuclear Information System (INIS)

    Geringer, T.; Bammer, M.; Ablber, M.

    2004-01-01

    Within the next few years, there'll be a lot of new challenges required from radiation protection. According to EU regulation[1] and the new austrian radiation protection law [2] regular additional training are requested. Patients protection in diagnostic and therapeutic usage of ionising radiation gains also more and more importance.[3] Not really surprisingly, the general population is definitely highly aware of the risks coming with the usage of radionuclides and x-rays in medicine. Furthermore, the nuclear power plant in Temelin, near the austrian border initiated a lively discussion about risks, necessity and use of ionising radiation in medicine and industry. It turned out to be a really hard job handling these topics in public. A brilliant didactics based on independent information and viewpoints was required. ARC Seibersdorf Research GmbH, represented by the department of medical technical applications and the radiation protection academy, developed an interactive CD-ROM covering several applications: Basics on radiation protection for medical and technical personnel ; preparation for a radiation protection training. Repetition of the main topics for graduates of a radiation protection training. Basics on radiation protection and emergency management for medical staff as well as for the general public. (Author)

  2. CD-ROM nutrient analysis database assists self-monitoring behavior of active duty Air Force personnel receiving nutrition counseling for weight loss.

    Science.gov (United States)

    Heetderks-Cox, M J; Alford, B B; Bednar, C M; Heiss, C J; Tauai, L A; Edgren, K K

    2001-09-01

    This study observed the effect of using a computerized vs manual method of self-monitoring among Air Force personnel receiving nutrition counseling for weight loss. Subjects who enrolled during the first 2 weeks of the 4-week recruitment period completed food records for 6 weeks using a CD-ROM nutrient database (intervention group) whereas those who enrolled during the last 2 weeks used a food record booklet (comparison group). Of the 42 subjects (n = 23 intervention group and n = 19 comparison group), only 113 intervention and 11 comparison group subjects (57% of study enrollees) submitted at least 1 food record during the study and were included in the analysis, which included review of pre- and poststudy questionnaires, food records, and focus group data. There were no significant differences between the number of days per week documented or average number of items recorded daily. All 9 intervention as compared to 2 comparison group subjects who completed a poststudy questionnaire searched for lower-energy and lower-fat items and reported changing their dietary intake as a result. All intervention group subjects who participated in a focus group (n=6) had favorable comments about using the CD-ROM for monitoring and changing eating habits, indicating that it is a beneficial self-monitoring tool. Participants enjoyed the immediate dietary feedback, and computerized food records may be easier to interpret by nutrition counselors. A number of computerized nutrient databases are available to assist patients and consumers in managing nutritional concerns.

  3. Nuclides 2000: an electronic chart of the nuclides on CD-ROM

    International Nuclear Information System (INIS)

    Magill, J.

    2000-01-01

    The 'Nuclides 2000' software package is an electronic chart of the nuclides, available on CD-ROM for Microsoft Windows operating systems, which offers extensive basic information on physics and radiology of the familiar nuclides. Moreover, 'Nuclides 2000' contains codes for a number of applications which allow the required data to be computed quickly and reliably by means of interactive user guidance. The data and codes are supplemented by information in the format of contributions on the history of radioactivity and radiochemistry, and on subjects of interest in physics, such as C-14 dating and the generation of Ti-44 in a supernova, and by a link collection of Internet addresses. As a detailed database, 'Nuclides 2000' can be used for teaching, research, and for practical applications. (orig.) [de

  4. History, Development and Future of TRIGA Research Reactors. Companion CD-ROM

    International Nuclear Information System (INIS)

    2016-01-01

    Due to its particular fuel design and resulting enhanced inherent safety features, TRIGA reactors (Training, Research, Isotopes, General Atomics) constitute a ‘class of their own’ among the large variety of research reactors built world-wide. This publication summarizes in a single document the information on the past and present of TRIGA research reactors and presents an outlook in view of potential issues to be solved by TRIGA operating organizations in the near future. It covers the historical development and basic TRIGA characteristics, followed by utilization, fuel conversion and ageing management of TRIGA research reactors. It continues with issues and challenges, introduction to the global TRIGA research reactor network and concludes with future perspectives. This CD-ROM illustrates the historical developments of TRIGA research reactors through individual facility examples and experiences

  5. Data base management system and display software for the National Geophysical Data Center geomagnetic CD-ROM's

    Science.gov (United States)

    Papitashvili, N. E.; Papitashvili, V. O.; Allen, J. H.; Morris, L. D.

    1995-01-01

    The National Geophysical Data Center has the largest collection of geomagnetic data from the worldwide network of magnetic observatories. The data base management system and retrieval/display software have been developed for the archived geomagnetic data (annual means, monthly, daily, hourly, and 1-minute values) and placed on the center's CD-ROM's to provide users with 'user-oriented' and 'user-friendly' support. This system is described in this paper with a brief outline of provided options.

  6. Analysis of User Need with CD-ROM Databases: A Case Study Based on Work Sampling at One University Library.

    Science.gov (United States)

    Wells, Amy Tracy

    Analysis of the needs of users of Compact Disk-Read Only Memory (CD-ROM) was performed at the Tampa campus of the University of South Florida. A review of the literature indicated that problems associated with selecting the appropriate database, searching, and requiring technical assistance were the probable areas of user need. The library has 17…

  7. Effects of the CD-Rom Version of the "Self-Advocacy Strategy" on Quality of Contributions in IEP Meetings of High School Students with Intellectual Disability

    Science.gov (United States)

    Cease-Cook, Jennifer; Test, David W.; Scroggins, La' Shawndra

    2013-01-01

    This study used a multiple-probe across participants design to examine the effects of the CD-Rom version of the "Self-Advocacy Strategy" on quality of contributions in Individual Education Plan (IEP) meetings of five high school students with intellectual disability. Results indicated a functional relationship between using the CD-Rom…

  8. Review of World of Money CD-ROM for PC/Mac [CD-ROM

    Directory of Open Access Journals (Sweden)

    Philip de Jersey

    1998-12-01

    Full Text Available Following on from the impressive development of the new HSBC Money Gallery in 1997, the British Museum has launched into the world of electronic publishing with the World of Money, an "interactive exploration of money worldwide from ancient times to the present day". Intended for ages ten to adult, the CD promises "a mine of information about the use, form, history and importance of money around the globe", and "fun and information for all the family". Reviewing in a Mac-unfriendly environment, I have been able to run the CD only on a PC. On a 166Mhz MMX with 32Mb RAM and a 12x CD it runs impressively quickly, with no more than two or three seconds of the "loading new page" display when switching between different parts of the program. Minimum requirements are listed as a 486 with 8Mb RAM, 40Mb free hard disk space, Windows 3.11 or Windows 95, 4x CD drive, 1Mb 256 colours graphics card, 16-bit Sound Blaster compatible sound card, and a VGA monitor. Minimum requirements for the Mac are listed as System 7, 603e processor, 16Mb RAM, 40MB free hard disk space, 6x CD drive, 1Mb video card and Apple monitor or Multisync with adaptor. The CD opens with an image of the British Museum portico, through which we are taken into the foyer, complete with the sound effects of massed ranks of tourists. We have four options available on a lectern, or by turning left, right or going upstairs: History of Money, Information Centre, Activities, and Options. Clicking on a large question mark brings up the Help screens (Figure 1.

  9. Proceedings of the High Performance Embedded Computing Workshop (HPEC 2006) (10th). Held in Lexington, Massachusetts on September 19-21, 2006 (CD-ROM)

    National Research Council Canada - National Science Library

    Kepner, Jeremy

    2007-01-01

    ...: 1 CD-ROM; 4 3/4 in.; 78.3 MB. ABSTRACT: The High-Performance Embedded Computing (HPEC) technical committee announced the tenth annual HPEC Workshop held in September 2006 at MIT Lincoln Laboratory in Lexington, MA...

  10. School Survey on Crime and Safety (SSOCS) 2000 Public-Use Data Files, User's Manual, and Detailed Data Documentation. [CD-ROM].

    Science.gov (United States)

    National Center for Education Statistics (ED), Washington, DC.

    This CD-ROM contains the raw, public-use data from the 2000 School Survey on Crime and Safety (SSOCS) along with a User's Manual and Detailed Data Documentation. The data are provided in SAS, SPSS, STATA, and ASCII formats. The User's Manual and the Detailed Data Documentation are provided as .pdf files. (Author)

  11. The Lunar Source Disk: Old Lunar Datasets on a New CD-ROM

    Science.gov (United States)

    Hiesinger, H.

    1998-01-01

    A compilation of previously published datasets on CD-ROM is presented. This Lunar Source Disk is intended to be a first step in the improvement/expansion of the Lunar Consortium Disk, in order to create an "image-cube"-like data pool that can be easily accessed and might be useful for a variety of future lunar investigations. All datasets were transformed to a standard map projection that allows direct comparison of different types of information on a pixel-by pixel basis. Lunar observations have a long history and have been important to mankind for centuries, notably since the work of Plutarch and Galileo. As a consequence of centuries of lunar investigations, knowledge of the characteristics and properties of the Moon has accumulated over time. However, a side effect of this accumulation is that it has become more and more complicated for scientists to review all the datasets obtained through different techniques, to interpret them properly, to recognize their weaknesses and strengths in detail, and to combine them synoptically in geologic interpretations. Such synoptic geologic interpretations are crucial for the study of planetary bodies through remote-sensing data in order to avoid misinterpretation. In addition, many of the modem datasets, derived from Earth-based telescopes as well as from spacecraft missions, are acquired at different geometric and radiometric conditions. These differences make it challenging to compare or combine datasets directly or to extract information from different datasets on a pixel-by-pixel basis. Also, as there is no convention for the presentation of lunar datasets, different authors choose different map projections, depending on the location of the investigated areas and their personal interests. Insufficient or incomplete information on the map parameters used by different authors further complicates the reprojection of these datasets to a standard geometry. The goal of our efforts was to transfer previously published lunar

  12. Environmental Sensitivity Index (ESI) Atlas: Upper Texas Coast (NODC Accession 0046089)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This CD-ROM product from the NOAA National Ocean Service Hazardous Materials Response and Assessment Division contains the Environmental Sensitivity Index (ESI) data...

  13. Effects of Contract Delivery Method on the LEED(trademark) Score of U.S. Navy Military Construction Projects (Fiscal Years 2004-2006) (CD-ROM)

    National Research Council Canada - National Science Library

    Carpenter, Deanna S

    2005-01-01

    ...: 1 CD-ROM; 4 3/4 in.; 484 KB. ABSTRACT: This research study focused on determining the effects that the two major contract delivery methods had on the LEED score of projects over the design and construction time horizon...

  14. NODC Standard Product: Coastal Change Analysis Program (C-CAP) Chesapeake Bay Region Data from 1984 to 1989 on CD-ROM (NODC Accession 9200303)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The data set on this CD-ROM shows changes in land cover for the Chesapeake Bay region over the 5-year interval from 1984 to 1988-89. The data set was produced...

  15. Experience teaching CD-ROM-based course on CANDU nuclear-power-plant systems and operation

    International Nuclear Information System (INIS)

    Rouben, Benjamin

    2008-01-01

    This paper presents personal experience garnered from teaching a CD-ROM-based course on CANDU Power-Plant Systems and Operation. This course was originally developed by Prof. G.T. Bereznai as research in distance-learning techniques when he was directing the Thai-Canadian Human Resources Development Project at Chulalongkorn University in Bangkok. The course has been offered in a number of universities, including McMaster University and the University of Ontario Institute of Technology. All the course material, including lectures, assignments, and a simulator, is provided on a CD-ROM. Lectures include a spoken soundtrack covering the material. The class often includes both undergraduate and graduate students. I found that most students appreciate having the material on electronic format, which they can view and review at will and on their own time. Students find this course quite intensive - it covers all major systems in the CANDU reactor and power plant in detail. A very important component of the course is the simulator, which teaches students how systems operate in normal operation, in power manoeuvres, and during process-system malfunctions. Effort in absorbing the material and performing assignments can often exceed 10 hours per week. Some of the simulator assignments involve tricky manoeuvres, requiring several tries to achieve the expected result. Some assignments may take several hours, especially if the manoeuvres requiring repetition take 30 minutes or more in real time. I found that some instruction in the basic theory of reactor physics and systems is appreciated by students. A few possible enhancements to the simulator model were identified. Graduate students taking the course are required to do an additional project; I assigned an investigation of the effects of xenon-concentration changes during 1 week of load cycling. In summary, this course provides to students the opportunity to learn a great deal about the workings of CANDU-plant systems. (author)

  16. IAEA fast reactor knowledge preservation initiative. Project focus: KNK-II reactor, Karlsruhe, Germany

    International Nuclear Information System (INIS)

    2004-08-01

    This Working Material (including the attached CD-ROM) documents progress made in the IAEA's initiative to preserve knowledge in the fast reactor domain. The brochure describes briefly the context of the initiative and gives an introduction to the contents of the CD-ROM. In 2003/2004 a first focus of activity was concentrated on the preservation of knowledge related to the KNK-II experimental fast reactor in Karlsruhe, Germany. The urgency of this project was given by the impending physical destruction of the installation, including the office buildings. Important KNK-II documentation was brought to safety and preserved just in time. The CD-ROM contains the full texts of 264 technical and scientific documents describing research, development and operating experience gained with the KNK-II installation over a period of time from 1965 to 2002, extending through initial investigations, 17 years of rich operating experience, and final shutdown and decommissioning. The index to the documents on the CD-ROM is printed at the end of this booklet in chronological order and is accessible on the CD by subject index and chronological index. The CD-ROM contains in its root directory also the document 'fr c lassification.pdf' which describes the classification system used for the present collection of documents on the fast reactor KNK-II

  17. The use of CD-ROMs for storage and document delivery at the British Library Document Supply Centre

    International Nuclear Information System (INIS)

    Bradbury, D.

    1990-05-01

    The British Library Document Supply Centre (BLDSC) has been in the forefront of international document delivery for 20 years. During the last 5 years it has been very actively involved in the ADONIS Project, through which the full text of some 200 journals in the life sciences have been stored, accessed, and delivered through the medium of CD-ROM. The BLDSC's involvement in this project is described and indications of the lessons learned and of the implications for international document delivery systems in the future are given. (author)

  18. The use of CD-ROMs for storage and document delivery at the British Library Document Supply Centre

    Energy Technology Data Exchange (ETDEWEB)

    Bradbury, D [British Library Document Supply Centre, Boston SPA (United Kingdom)

    1990-05-01

    The British Library Document Supply Centre (BLDSC) has been in the forefront of international document delivery for 20 years. During the last 5 years it has been very actively involved in the ADONIS Project, through which the full text of some 200 journals in the life sciences have been stored, accessed, and delivered through the medium of CD-ROM. The BLDSC`s involvement in this project is described and indications of the lessons learned and of the implications for international document delivery systems in the future are given. (author).

  19. The use of U.S. Geological Survey CD-ROM-based petroleum assessments in undergraduate geology laboratories

    Science.gov (United States)

    Eves, R.L.; Davis, L.E.; Dyman, T.S.; Takahashi, K.I.

    2002-01-01

    Domestic oil production is declining and United States reliance on imported oil is increasing. America will be faced with difficult decisions that address the strategic, economic, and political consequences of its energy resources shortage. The geologically literate under-graduate student needs to be aware of current and future United States energy issues. The U.S. Geological Survey periodically provides energy assessment data via digitally-formatted CD-ROM publications. These publications are free to the public, and are well suited for use in undergraduate geology curricula. The U.S. Geological Survey (USGS) 1995 National Assessment of United States Oil and Gas Resources (Digital Data Series or DDS-30) (Gautier and others, 1996) is an excellent resource for introducing students to the strategies of hydrocarbon exploration and for developing skills in problem-solving and evaluating real data. This paper introduces the reader to DDS-30, summarizes the essential terminology and methodology of hydrocarbon assessment, and offers examples of exercises or questions that might be used in the introductory classroom. The USGS contact point for obtaining DDS-30 and other digital assessment volumes is also provided. Completing the sample exercises in this report requires a copy of DDS-30.

  20. Students' and teachers' perceptions of motivation and learning through the use in schools of multimedia encyclopaedias on CD-ROM

    OpenAIRE

    Wishart , Jocelyn

    2000-01-01

    This article is the result of interviews with teachers, students, and school librarians in eight UK secondary schools regarding their use of multimedia encyclopaedias on CD-ROM. It focuses on a content analysis of their comments on how having access to multimedia encyclopaedias changes the way students work and learn in school, how they perceive it enhances their learning, and how it hinders it. Teachers reported that they used multimedia encyclopaedias as an additional information resource, ...

  1. Diffusivity database (DDB) system for major rocks (Version of 2006/specification and CD-ROM)

    International Nuclear Information System (INIS)

    Tochigi, Yoshikatsu; Sasamoto, Hirosi; Shibata, Masahiro; Sato, Haruo; Yui, Mikazu

    2006-03-01

    The development of the database system has been started to manage with the generally used. The database system has been constructed based on datasheets of the effective diffusion coefficient of the nuclides in the rock matrix in order to be applied on the 'H12: Project to Establish the Scientific and Technical Basis for HLW Disposal in Japan'. In this document, the examination and expansion of the datasheet structure and the process of construction of the database system and conversion of all data existing on datasheets are described. As the first step of the development of the database, this database system and its data will continue to be updated and the interface will be revised to improve the availability. The developed database system is attached on the CD-ROM as the file format of Microsoft Access. (author)

  2. On-line vs DC-ROM delivery of information

    NARCIS (Netherlands)

    Waaijers, L.

    1992-01-01

    Considers the use of new technologies in library information delivery systems. Discusses the virtues of paper, CD-ROM, and online media in terms of accessibility, timeliness, compactness, searchability, preservability, authenticity, and appearance, as well as end user benefit. Surmises that

  3. Review of The Earl of Abergavenny. Historical Record and Wreck Excavation CD-Rom

    Directory of Open Access Journals (Sweden)

    David Petts

    2003-06-01

    Full Text Available In early February 1805 a small fleet of East Indiamen accompanied by the frigate Weymouth set sail from Portsmouth heading first for Bengal and ultimately for China. However, barely had the voyage began when, following bad weather and confusion, one of the boats, the Earl of Abergavenny, struck the Shambles bank just off Portland Bill. Although the crew managed to free it, it was so badly damaged it sank while trying to make for the safety of Weymouth. Over 250 crew and passengers drowned. The wreck has until now been best known for causing the death of John Wordsworth, the ship's commander and brother of the poet William Wordsworth. This excellent CD report of archaeological investigations on the wreck site carried out since 1980 by the Weymouth Underwater Archaeological Group (WUAG brings us the full picture of the events leading up to the wreck, and a record of the remains found by the team of divers (Fig.1. The complex campaigns of diving have been carried out alongside extensive documentary and historical work. The huge amount of data created by this project has inevitably led to challenges for the WUAG regarding its publication (Cumming 2002. The decision to publish via a CD-ROM has allowed very large quantities of data and discussion to be published. The current version of the CD contains over 100,000 words of text, 1560 files and over 1000 illustrations (JPEGS. All for the grand price of 10 GBP. The volume can be browsed using a commercially available browser but is also supplied as compiled file using Web Compiler, which has the advantage of a search facility.

  4. Method for a dummy CD mirror server based on NAS

    Science.gov (United States)

    Tang, Muna; Pei, Jing

    2002-09-01

    With the development of computer network, information sharing is becoming the necessity in human life. The rapid development of CD-ROM and CD-ROM driver techniques makes it possible to issue large database online. After comparing many designs of dummy CD mirror database, which are the embodiment of a main product in CD-ROM database now and in near future, we proposed and realized a new PC based scheme. Our system has the following merits, such as, supporting all kinds of CD format; supporting many network protocol; the independence of mirror network server and the main server; low price, super large capacity, without the need of any special hardware. Preliminarily experiments have verified the validity of the proposed scheme. Encouraged by the promising application future, we are now preparing to put it into market. This paper discusses the design and implement of the CD-ROM server detailedly.

  5. Processing of Irradiated Graphite to Meet Acceptance Criteria for Waste Disposal. Results of a Coordinated Research Project. Companion CD-ROM

    International Nuclear Information System (INIS)

    2016-05-01

    Graphite is widely used in the nuclear industry and in research facilities and this has led to increasing amounts of irradiated graphite residing in temporary storage facilities pending disposal. This publication arises from a coordinated research project (CRP) on the processing of irradiated graphite to meet acceptance criteria for waste disposal. It presents the findings of the CRP, the general conclusions and recommendations. The topics covered include, graphite management issues, characterization of irradiated graphite, processing and treatment, immobilization and disposal. Included on the attached CD-ROM are formal reports from the participants

  6. Quality Management Audits in Nuclear Medicine Practices. 2. Ed. Companion CD-ROM

    International Nuclear Information System (INIS)

    2015-01-01

    Quality management systems are essential and should be maintained with the intent to continuously improve effectiveness and efficiency, enabling nuclear medicine to achieve the expectations of its quality policy, satisfy its customers and improve professionalism. The quality management (QM) audit methodology in nuclear medicine practice, introduced in this publication, is designed to be applied to a variety of economic circumstances. A key outcome is a culture of reviewing all processes of the clinical service for continuous improvement in nuclear medicine practice. Regular quality audits and assessments are vital for modern nuclear medicine services. More importantly, the entire QM and audit process has to be systematic, patient oriented and outcome based. The management of services should also take into account the diversity of nuclear medicine services around the world and multidisciplinary contributions. The latter include clinical, technical, radiopharmaceutical, medical physics and radiation safety procedures. This companion CD-ROM is attached to the printed STI/PUB/1683 and contains the full-text of STI/PUB/1683 as well as checklists in PDF and Excel format and a table with the contents of a standardized audit report

  7. Technical and Scientific Support Organizations Providing Support to Regulatory Functions. Companion CD-ROM

    International Nuclear Information System (INIS)

    2018-01-01

    This publication introduces the general principles underlying the provision of technical and scientific support to a regulatory body and the characteristics of organizations providing such support. It describes the services provided to support regulatory functions as well as the associated activities and processes to maintain the needed level of expertise, state of the art tools and equipment. The publication is intended for use primarily by organizations that provide technical and scientific support in the field of nuclear and radiation safety. This also includes organizations that acquire such support, and regulatory bodies and governments, as they make decisions on the model of technical and scientific support to be developed at the national level, for example in the case of a country embarking on the development of a nuclear power programme. It is the first IAEA publication dedicated to the specific practices and challenges to be met by the technical and scientific support organizations. This CD-ROM includes the annexes to the printed publication of examples of TSOs and their interactions with key stakeholders.

  8. Ionospheric Electron/Ion Densities Temperatures on CD-ROM and WWW

    Science.gov (United States)

    Bilitza, Dieter; Papitashvili, Natasha; Schar, Bill; Grebowsky, Joseph

    2002-01-01

    As part of this project a large volume of ionospheric satellite insitu data from the sixties, seventies and early eighties were made accessible online in ASCII format for public use. This includes 14 data sets from the BE-B, Alouette 2, DME-A, AE-B, ISIS-1, ISIS-2, OGO-6, DE-2, AEROS-A, AE-C, AE-D, AE-E, and Hinotori satellites. The original data existed in various machine-specific, highly compressed, binary encoding on 7-, or 9-track magnetic tapes. The data were decoded and converted to a common ASCII data format, solar and magnetic indices were added, and some quality control measures were taken. The original intent of producing CD-ROMs with these data was overtaken by the rapid development of the Internet. Most users now prefer to obtain the data directly online and greatly value WWW-interfaces to browse, plot and subset the data. Accordingly the data were made available online on the anonymous ftp site of NASA's National Space Science Data Center (NSSDC) at ftp://nssdcftp.gsfc.nasa.gov/spacecraft data/ and on NSSDC's ATMOWeb (http://nssdc.gsfc.nasa.gov/atmoweb/), a WWW-interface for plotting, subsetting, and downloading the data. Several new features were implemented into ATMOWeb as part of this project including a filtering and scatter plot capability. The availability of this new database and WWW system was announced through several electronic mailer (AGU, CEDAR, IRI, etc) and through talks and posters during scientific meetings.

  9. Volcanoes of México: An Interactive CD-ROM From the Smithsonian's Global Volcanism Program

    Science.gov (United States)

    Siebert, L.; Kimberly, P.; Calvin, C.; Luhr, J. F.; Kysar, G.

    2002-12-01

    The Smithsonian Institution's Global Volcanism Program is nearing completion of an interactive CD-ROM, the Volcanoes of México. This CD is the second in a series sponsored by the U.S. Department of Energy Office of Geothermal Technologies to collate Smithsonian data on Quaternary volcanism as a resource for the geothermal community. It also has utility for those concerned with volcanic hazard and risk mitgation as well as an educational tool for those interested in Mexican volcanism. We acknowledge the significant contributions of many Mexican volcanologists to the eruption reports, data, and images contained in this CD, in particular those contributions of the Centro Nacional de Prevencion de Desastres (CENAPRED), the Colima Volcano Observatory of the University of Colima, and the Universidad Nacional Autónoma de México (UNAM). The Volcanoes of México CD has a format similar to that of an earlier Smithsonian CD, the Volcanoes of Indonesia, but also shows Pleistocene volcanic centers and additional data on geothermal sites. A clickable map of México shows both Holocene and Pleistocene volcanic centers and provides access to individual pages on 67 volcanoes ranging from Cerro Prieto in Baja California to Tacaná on the Guatemalan border. These include geographic and geologic data on individual volcanoes (as well as a brief paragraph summarizing the geologic history) along with tabular eruption chronologies, eruptive characteristics, and eruptive volumes, when known. Volcano data are accessible from both geographical and alphabetical searches. A major component of the CD is more than 400 digitized images illustrating the morphology of volcanic centers and eruption processes and deposits, providing a dramatic visual primer to the country's volcanoes. Images of specific eruptions can be directly linked to from the eruption chronology tables. The Volcanoes of México CD includes monthly reports and associated figures and tables cataloging volcanic activity in M

  10. English grammar in use a self-study reference and practice book for intermediate learners of English : with answers and CD-ROM

    CERN Document Server

    Murphy, Raymond

    2012-01-01

    English Grammar in Use Fourth edition is an updated version of the world's best-selling grammar title. It has a fresh, appealing new design and clear layout, with revised and updated examples, but retains all the key features of clarity and accessibility that have made the book popular with millions of learners and teachers around the world. The CD-ROM contains lots of additional practice exercises to consolidate learning, ideal for self-study but also suitable for reinforcement work in the classroom. An online version and book without answers are available separately.

  11. [Modern referral-information service in the Central Medical Library of the University of Zagreb Medical School].

    Science.gov (United States)

    Hadjina, G; Granić, D; Bekavac, A

    1990-01-01

    New technologies in information and retrieval services of the Central Medical Library are presented, as well as comparison between traditional search of biomedical literature and search of biomedical bases available on CD-ROM and on-line. MeSH thesaurus represents the basis for all modes of searches, either through published indexes (Index Medicus, Biomedicina Iugoslavica), searches through on-line, or via CD-ROM technology. Experience in indexing according to MeSH structure helps us to search and retrieve biomedical literature on new media too. Great interest in new media for search and retrieval of biomedical literature among our users (100%) justifies their introduction into the Library. In the period of four months, 75% of our users chose CD-ROM technology in their search, 25% chose on-line search, and both technologies were combined by 33% of the users. Having these new media in our library we have reached the point from which we join the world biomedical information network and successfully meet the growing need for information in the field of biomedicine.

  12. Analysis of potential energy saving strategies in a Bangkok school building. With CD-ROM; Analyse von Energieeinsparpotentialen am Beispiel einer Schule in Bangkok

    Energy Technology Data Exchange (ETDEWEB)

    Temming, H.V.

    2000-05-01

    In cooperation with the Gesellschaft fuer technische Zusammenarbeit GTZ, a school building in Thailand was selected for an analysis of potentials for energy saving. The selected school was the New International School of Thailand (NIST) in Bangkok. Energy-relevant data were acquired by measurements, and solutions for more efficient energy supply were developed. Recommendations were made on this basis. This dissertation is also available on CD-ROM. [German] In Zusammenarbeit mit der Gesellschaft fuer technische Zusammenarbeit GTZ wurde als Beispielobjekt eine thailaendische Schule, die New International School of Thailand (NIST) in Bangkok ausgewaehlt. An diesem Objekt wurden die verschiedenen energetischen Messungen durchgefuehrt. Diese wurden bedarfsgerecht ausgewertet. Auf der Basis der Ergebnisse wurden Loesungsmoeglichkeiten fuer eine effizientere Energieversorgung der Schule konstruiert und diese Alternativen wie oben beschrieben bewertet, woraus sich entsprechende Empfehlungen ergeben. Der Aufbau dieser Arbeit stellt sich nun folgendermassen dar: Nachdem in einem ersten Schritt die fuer diesen Kontext wichtigsten Parameter Thailands und des Untersuchungsobjektes dargestellt werden, schliesst sich hieran die Vorstellung verschiedener technische Alternativen zur Erzeugung von Kaelte an, da hier ein Fokus fuer moegliche Energieeinsparungen gesetzt wird. Anschliessend werden einige in der Arbeit verwandte Berechnungsverfahren fuer energetische oder wirtschaftliche Zuammenhaenge sowie eine ausfuehrliche Beschreibung der energetischen 1st-Situation des Untersuchungsobjektes dargestellt. Darauf aufbauend folgt nun die Vorstellung der verschiedenen Energieeinsparpotentiale durch technische und verhaltensinduzierte Optimierungsmassnahmen. Diese Arbeit endet mit der Bewertung aller aufgedeckten Potentiale und einem Gesamtfazit aus der Untersuchung. (Diese Diplomarbeit liegt auch in Form einer CD-ROM vor.) (orig./AKF)

  13. Thoracic ROM measurement system with visual bio-feedback: system design and biofeedback evaluation.

    Science.gov (United States)

    Ando, Takeshi; Kawamura, Kazuya; Fujitani, Junko; Koike, Tomokazu; Fujimoto, Masashi; Fujie, Masakatsu G

    2011-01-01

    Patients with diseases such as chronic obstructive pulmonary disease (COPD) need to improve their thorax mobility. Thoracic ROM is one of the simplest and most useful indexes to evaluate the respiratory function. In this paper, we have proposed the prototype of a simple thoracic ROM measurement system with real-time visual bio-feedback in the chest expansion test. In this system, the thoracic ROM is measured using a wire-type linear encoder whose wire is wrapped around the thorax. In this paper, firstly, the repeatability and reliability of measured thoracic ROM was confirmed as a first report of the developed prototype. Secondly, we analyzed the effect of the bio-feedback system on the respiratory function. The result of the experiment showed that it was easier to maintain a large and stable thoracic ROM during deep breathing by using the real-time visual biofeedback system of the thoracic ROM.

  14. A Novel Index Using Soluble CD36 Is Associated with the Prevalence of Type 2 Diabetes Mellitus: Comparison Study with Triglyceride-Glucose Index.

    Science.gov (United States)

    Kim, Ho Jin; Moon, Jun Sung; Park, Il Rae; Kim, Joong Hee; Yoon, Ji Sung; Won, Kyu Chang; Lee, Hyoung Woo

    2017-09-01

    Plasma soluble cluster determinant 36 (sCD36) level is closely related with insulin resistance and atherosclerosis, but little is known whether it could be a surrogate for estimating risk of developing diabetes or not. To address this, we evaluated association between sCD36 index, the product of sCD36 and fasting plasma glucose (FPG), and the prevalence of type 2 diabetes mellitus (T2DM), and then compared with triglyceride-glucose (TyG) index which has been suggested simple index for insulin resistance. This was cross-sectional study, and participants were classified as normal glucose tolerance (NGT), prediabetes, and T2DM according to glucose tolerance. The formula of TyG index was 'ln [FPG (mg/dL)×triglyceride (mg/dL)/2],' and the sCD36 index was 'ln [sCD36 (pg/mL)×FPG (mg/dL)/2].' One hundred and fifty-five subjects (mean age, 55.2 years) were enrolled, and patients with T2DM were 75. Both indexes were significantly increased in prediabetes and T2DM rather than NGT, and sCD36 index was positively correlated with both glycosylated hemoglobin and homeostasis model assessment of insulin resistance (r=0.767 and r=0.453, respectively; Pindex for T2DM was 4.39 (95% confidential interval, 1.51 to 12.77) after adjusting age, gender, blood pressure, smoking, alcohol, non-high density lipoprotein cholesterol and high-sensitivity C-reactive protein. However, OR of TyG index did not remained significance after adjustment. sCD36 index has an independent association with the risk of T2DM, and showed better correlation than TyG index. These results suggest sCD36 index might be useful surrogate marker for the risk of diabetes. Copyright © 2017 Korean Endocrine Society

  15. Neutrophil and Monocyte CD64 and CD163 Expression in Critically Ill Neonates and Children with Sepsis: Comparison of Fluorescence Intensities and Calculated Indexes

    Directory of Open Access Journals (Sweden)

    Mojca Groselj-Grenc

    2008-01-01

    Full Text Available Objective. To evaluate the expression of CD64 and CD163 on neutrophils and monocytes in SIRS with/without sepsis and to compare the diagnostic accuracy of CD64 and CD163 molecules expression determined as (1 mean fluorescence intensities (MFI of CD64 and CD163; and (2 the ratio (index of linearized MFI to the fluorescence signal of standardized beads. Patients and methods. Fifty-six critically ill neonates and children with systemic inflammatory response syndrome (SIRS and suspected sepsis, classified into two groups: SIRS with sepsis (n=29 and SIRS without sepsis (n=27. Results. CD64 and CD163 MFI measured on neutrophils and monocytes were elevated in patients with SIRS with sepsis. Diagnostic accuracy of indexes was equal to diagnostic accuracy of MFI for CD64 on neutrophils (0.833 versus 0.854 for day 0 and 0.975 versus 0.983 for day 1 and monocytes (0.811 versus 0.865 for day 0 and 0.825 versus 0.858 for day 1, and CD163 on neutrophils (0.595 versus 0.655 for day 0 and 0.677 versus 0.750 for day 1, but not for CD163 on monocytes. Conclusion. CD64 MFI, CD163 MFI, CD64 indexes for neutrophils and monocytes, and CD163 index for neutrophils can all be used for discrimination of SIRS and sepsis in critically ill neonates and children. CD64 index for neutrophils, however, is superior to all other markers.

  16. Indexing of Popular Periodicals: The State of the Art

    Science.gov (United States)

    Aveney, Brian; Slade, Rod

    1978-01-01

    Nine indexing services of popular periodicals are discussed in terms of content, coverage, and characteristics: Access, Consumers Index, Index to Free Periodicals, New York Times Information Bank, Magazine Index, Monthly Periodicals Index, New Periodicals Index, Popular Periodical Index, and Readers Guide. A table indicates coverage for each index…

  17. The Distribution of Information: The Role for Online Public Access Catalogs.

    Science.gov (United States)

    Matthews, Joseph R.

    1994-01-01

    Describes the Online Public Access Catalog (OPAC) and the inclusion of abstracting and indexing industry databases in OPACs. Topics addressed include the implications of including abstracting and indexing tape and CD-ROM products in OPACs; the need for standards allowing library systems to communicate with dissimilar CD-ROM products; and computer,…

  18. The Virtual 3D Reconstruction of the East Pediment of the Temple of Zeus at Olympia – Presentation of an Interactive CD-ROM

    Directory of Open Access Journals (Sweden)

    András PATAY-HORVÁTH Patay-Horváth

    2011-12-01

    Full Text Available The paper gives an overview of a two-years project concerning a major monument of ancient Greek art and presents the interactive, bilingual (English/Hungarian CD-ROM, which is intended to summarize and visualize its final results. The presented project approaches a century-old controversy in a new way by producing a virtual 3D reconstruction of a monumental marble group. Digital models of the statues were produced by scanning the original fragments and by reconstructing them virtually. The virtual model of the pediment surrounding the sculptures was prepared on the basis of the latest architectural studies and afterwards the reconstructed models were inserted in this frame, in order to test the technical feasibility and aesthetic effects the four possible arrangements. The resulting models enable easy and very instructive experimentation, which would be otherwise impossible with the originals and/or very expensive and not very practicable with traditional tools (e.g. real-size plaster models. The complete model can effectively be used to verify the results of earlier or more recent reconstructions presented only in simple drawings. In addition, the 3D models of the individual fragments can be used for further research and for visualization.  The documentary CD-ROM presenting the full background, the methods and the conclusions of the project contains beside a comprehensive text various kinds of supporting documents (images, 3D models, papers, broadcasts, audiovisual material. It is addressed to a mixed audience: a picture gallery, a short documentary movie some other attachments including a selected bibliography is intended for the general public, but scholarly publications, presentations on related problems are also included for specialists interested in certain details.

  19. Deutsche Literatur von Frauen – Jetzt auch digital! Literature by German Women—Now on CD!

    Directory of Open Access Journals (Sweden)

    Corinna Heipcke

    2002-07-01

    Full Text Available Die Digitale Bibliothek hat eine CD-Rom ediert, auf der ein Querschnitt durch die Werke von Autorinnen aus vier Jahrhunderten enthalten ist. Die Volltexte sind integriert in ein Bearbeitungsprogramm, das quellentreues Zitieren und Volltextrecherchen ermöglicht. Damit ist ein ausgesprochen praktisches Hilfsmittel für Germanistinnen und Germanisten entstanden. An ihre Grenzen gelangt die Sammlung allerdings bei der nicht unproblematischen Textauswahl.The editors of the Digital Library have tackled the task of creating a library which enables one to find any work that one may be interested in looking up or reading. Five years ago, a CD Rom entitled German Literature from Lessing to Kafka which present the complete works of select authors together with a programme that assists the user in better understanding their works. In so doing, however, women were almost completely omitted, as the entire CD only featured the works of four women authors. In order to overcome this shortcoming, Mark Lehmstedt edited the above-mentioned CD which contains the select works of 62 women authors from the baroque period to the Weimar Republic. Their works are accompanied by the latest software version of the Digital Library.

  20. A Novel Index Using Soluble CD36 Is Associated with the Prevalence of Type 2 Diabetes Mellitus: Comparison Study with Triglyceride-Glucose Index

    OpenAIRE

    Kim, Ho Jin; Moon, Jun Sung; Park, Il Rae; Kim, Joong Hee; Yoon, Ji Sung; Won, Kyu Chang; Lee, Hyoung Woo

    2017-01-01

    Background Plasma soluble cluster determinant 36 (sCD36) level is closely related with insulin resistance and atherosclerosis, but little is known whether it could be a surrogate for estimating risk of developing diabetes or not. To address this, we evaluated association between sCD36 index, the product of sCD36 and fasting plasma glucose (FPG), and the prevalence of type 2 diabetes mellitus (T2DM), and then compared with triglyceride-glucose (TyG) index which has been suggested simple index ...

  1. ChemSkill Builder 2000, Version 6.1 [CD-ROM] (by James D. Spain and Harold J. Peters)

    Science.gov (United States)

    Keeney-Kennicutt, Reviewed By Wendy L.

    2000-07-01

    One of the major challenges for faculty teaching general chemistry is how to encourage students to practice solving problems. We know that for students to develop chemical intuition and problem-solving skills, they must "get their hands dirty" as they decipher and unravel problems inherent to our discipline. One tool that I've used since its release in 1996 is the ChemSkill Builder, an electronic homework package. The latest version, ChemSkill Builder (CSB) 2000, version 6.1, is an excellent, effective integration of teaching and testing most quantitative and conceptual learning objectives in an interactive way. It is inexpensive and easy to use for both students and faculty. The CSB 2000 package of personalized problem sets, specifically designed to complement most general chemistry courses, is a program on CD-ROM for PC Windows users (3.1, 95, or 98), with more than 1500 questions and a 3 1/2-in. record-management disk. There is a separate grade-management disk for the instructor. It has 24 gradable chapters, each with 5 or 6 sections, plus two new chapters that are not graded: Polymer Chemistry and an Appendix of Chemical Skills. Each section begins with a short review of the topic and many have interactive explanations. If students miss an answer, they are given a second chance for 70% credit. If they still miss, the worked-out solution is presented in detail. Students can work each section as many times as they wish to improve their scores. Periodically, the students download their data directly into a PC set up by the instructor. The data can be easily converted into an ASCII file and merged with a spreadsheet. The use of CD-ROM solves the sporadic problems associated with previous versions on 3 1/2-in. disks: software glitches, failed disks, and system incompatibilities. The quality and number of graphics and interactive exercises are much improved in this latest version. I particularly enjoyed the interactive explanations of significant figures and

  2. Arkitekturen, Roms moderne bygningsværker

    DEFF Research Database (Denmark)

    Hansen, Peter Mandal

    2012-01-01

    Artikel om Roms moderne og nutidige arkitektur med beskrivelse og analyse af et udvalg af Roms markante bygningsværker.......Artikel om Roms moderne og nutidige arkitektur med beskrivelse og analyse af et udvalg af Roms markante bygningsværker....

  3. The development and pilot testing of a multimedia CD-ROM for diabetes education.

    Science.gov (United States)

    Castaldini, M; Saltmarch, M; Luck, S; Sucher, K

    1998-01-01

    The multimedia CD-ROM program, Take Charge of Diabetes, was found to be accurate, easy to use, and enjoyable by the clients and health professionals who completed the pilot study. Participants perceived an increase in knowledge after completing the five modules. Two of the participants verbally stated that the program clarified information for them and they wished they had had such a program when they were first diagnosed with diabetes. Further evaluation is needed to generalize the effect of the program on knowledge of diabetes because the pilot study was not designed to fully evaluate the effectiveness of the program on knowledge level or behavior change. Behavior change resulting in better control of blood sugar levels and hemoglobin A1c within normal range is the goal for diabetes education. The person who lives with diabetes must learn self-care methods. To accomplish that, the person must be able to comprehend the material presented. CAI programs provide an individualized, interactive, and interesting way to learn about diabetes and self-care, using visual effects and audio to support the written text. CAI can provide an element of excitement that is not available with other conventional methods. Providing prompt reinforcement of correct answers in quiz sections and including positive written messages can increase patients' self-confidence and self-esteem. Computer-assisted instruction is not intended to replace personal contact with physicians and diabetes educators, but rather complement this contact, reinforce learning, and possibly increase self-motivation to take charge of one's diabetes.

  4. Quantitative Characterization of the Toxicities of Cd-Ni and Cd-Cr Binary Mixtures Using Combination Index Method

    Directory of Open Access Journals (Sweden)

    Lingyun Mo

    2016-01-01

    Full Text Available Direct equipartition ray design was used to construct Cd-Ni and Cd-Cr binary mixtures. Microplate toxicity analysis was used to evaluate the toxicity of individual substance and the Cd-Ni and Cd-Cr mixtures on Chlorella pyrenoidosa and Selenastrum capricornutum. The interacting toxicity of the mixture was analyzed with concentration addition (CA model. In addition, combination index method (CI was proposed and used to quantitatively characterize the toxicity of the binary mixtures of Cd-Ni and Cd-Cr observed in experiment and find the degree of deviation from the predicted outcome of the CA model, that is, the intensity of interacting toxicity. Results indicate that most of the 20 binary mixtures exhibit enhancing and synergistic effect, and only Cd-Cr-R4 and Cd-Cr-R5 mixtures have relatively high antagonistic effects against C. pyrenoidosa. Based on confidence interval, CI can compare the intensities of interaction of the mixtures under varying levels of effect. The characterization methods are applicable for analyzing binary mixture with complex interaction.

  5. Cern DD4424 ROM Diode Matrix

    CERN Multimedia

    A diode matrix is an extremely low-density form of read-only memory. It's one of the earliest forms of ROMs (dating back to the 1950s). Each bit in the ROM is represented by the presence or absence of one diode. The ROM is easily user-writable using a soldering iron and pair of wire cutters.This diode matrix board is a floppy disk boot ROM for a PDP-11, and consists of 32 16-bit words. When you access an address on the ROM, the circuit returns the represented data from that address.

  6. Significance of measuring oxidative stress in lifestyle-related diseases from the viewpoint of correlation between d-ROMs and BAP in Japanese subjects

    International Nuclear Information System (INIS)

    Fukui, Toshiki; Yamauchi, Kazuhiro; Maruyama, Mie; Yasuda, Tadashi; Abe, Youichi; Kohno, Masakazu

    2011-01-01

    In recent years, oxidative stress has been postulated to be an important factor in the pathogenesis and development of lifestyle-related diseases. In this study, we investigated the association between the derivatives of reactive oxygen metabolites (d-ROMs), as an index of products of reactive oxygen species (ROS), and biological antioxidant potential (BAP), as an index of antioxidant potential. We also investigated the associations between d-ROMs or BAP and the risk factors for lifestyle-related diseases or metabolic syndrome-associated factors to evaluate their usefulness in preventive medicine. There were 442 subjects who underwent health checkup examination in our facilities. In addition to standard medical checkup items, we analyzed d-ROMs, BAP, brachial-ankle pulse wave velocity, high-sensitivity C-reactive protein level and visceral fat area (VFA) visualized on a computed tomography scan. The mean d-ROM value in females was significantly higher than that in males. There was a positive correlation between the d-ROM and VFA levels. On correlation analysis, there was a negative correlation between the d-ROM and creatinine levels. As factors that influence d-ROMs, the level of VFA was selected, suggesting the significance of oxidative stress measurement with d-ROMs. In addition, there was a positive correlation between d-ROMs and BAP values. Further research is required to resolve whether increased production of ROS or the antioxidant potential that can compensate for such an increase of ROS is more important in vivo. (author)

  7. SOFTWARE REVIEW: Multimedia Motion II. CD-ROM and Teacher's Guide

    Science.gov (United States)

    Scaife, Jon A.

    2000-05-01

    expect. This is an issue that is in the teacher's hands; the package is flexible enough to accommodate a wide range of learning aims. Audio clips are brief and to the point, with both female and male speakers. The commentary goes beyond the descriptive, raising interesting questions and issues and setting challenges for the user. The optional screen text is pitched at A-level. Video clips can be viewed at full screen, which is a big improvement over the first edition. There are some new clips and a few omissions from the first edition; further CDs of movie data are planned. Clips may be played forwards or backwards at various speeds using a scroll bar. This allows close control and analysis, which is useful for critical events in which changes are rapid, such as collisions. Printing of data and graphs is straightforward and the results are clear. Unlike the first edition, Multimedia Motion II only gives direct support to graphs with time as the abscissa. For graphs such as v(x) versus v(y), however, it is a simple matter to save the data directly into Excel or another spreadsheet. I encountered only one snag in using the CD: if I forgot to save my data before moving to a new clip I could not recover it. This failing could be mine, but I did try hard. The Teacher's Guide contains photocopiable worksheets and detailed discussion and graphs of the video clips. For each clip there is a section of `useful data and formulae'. The guide is not a necessity for using the CD-ROM but it would be a very handy A-level teaching resource, allowing the option of independent use by students. It is accompanied by a floppy disc containing sets of experimental data for the video clips, a useful option for quick demonstrations. In addition, the guide explains the interesting and creative option of making your own movie sequences from videotape, though access to a video card would be needed to do this. Imagine the motivational value of students recording themselves playing various sports, or

  8. School Library Supplement. Putting Your Library Automation System to Work [and] Using Videodiscs in Research Projects [and] Library Security: What to Look For [and] Expanding Library/Media Services with Media Retrieval [and] How to Network CD-ROMs (and) The School Library Resource Directory.

    Science.gov (United States)

    Karpisek, Marian; And Others

    1995-01-01

    Presents five articles and a company resource directory to help librarians successfully incorporate technology into school libraries. Discusses actual situations, examines student needs, and gives advice to help librarians with library automation systems, videodiscs, library security systems, media retrieval, networking CD-ROMs, and locating…

  9. Nonlinear Aerodynamic ROM-Structural ROM Methodology for Inflatable Aeroelasticity in Hypersonic Atmospheric Entry, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — ZONA Technology proposes to develop an innovative nonlinear structural reduced order model (ROM) - nonlinear aerodynamic ROM methodology for the inflatable...

  10. Kodak's New Photo CD Portfolio: Multimedia for the Rest of Us.

    Science.gov (United States)

    Bonime, Andrew

    1994-01-01

    Describes Photo CD Portfolio, an Eastman Kodak product that provides interactive multimedia CD-ROM production capability. The article focuses on the capabilities of the tool's simplest authoring system, Create It, which allows users to work with Photo CD, PICT, or TIFF images, add graphics, text and audio, and create menus with branching. (KRN)

  11. Nuclear medicine installations supervisors interactive course (CD-ROM)

    International Nuclear Information System (INIS)

    Williart, A.; Shaw, M.; Tellez, M.

    2000-01-01

    The professionals who work as Nuclear Medicine Installations Supervisors need a suitable training. This training must be based on the guidelines of the C.S.N. (the Spanish Agency for Nuclear Safety). The traditional training courses must comply with a set of requirements, that not always is possible to get: They are given in a settled place. They are developed during a time, more or less lengthy. This time is pre-established. However, the persons willing to follow these courses have some difficulties with the place and the time. Many of them do not live near the places where the courses are given, in general in big cities, while there are Nuclear Medicine Installations scattered through all Spain. Moreover in some occasions they have not available time to attend the courses. Many times, faced with so many obstacles, the option is not to do the suitable training course. In order to solve this kind of problems we offer an Interactive Training Course (supported by CD-ROM). The course contents are based on Spanish Regulations and on the Safety Guide, established by C.S.N., for approval Radioactive Installations Supervisors Training Courses. This guide includes General Topics for Radioactive Installations and Specific Subjects for Nuclear Medicine. (General topics) Basic knowledge on the fundamental concepts on the action and nature of Ionizing Radiations, their risks and preventions. The ionizing radiations. Biological effects of ionizing radiations. Radiological protection. Legislation on radioactive installations. (Specific Subjects) Knowledge on the radiological risks associated to the proper techniques in the specific field of application. In our case the specific field is Nuclear Medicine Installations, where the radioactive sources are used for diagnostic or for therapy. Specific legal and administrative aspects. Non-encapsulated radioactive sources. Associated radiological risks to the use of non-encapsulated sources. Installations design. Operative procedures

  12. Meteonorm. Global meteorological database for solar energy and applied climatology. Version 4.0: edition 2000. Software and data on CD-ROM

    International Nuclear Information System (INIS)

    1999-01-01

    This is a comprehensive meteorological planning tool for system design, targeted at engineers, architects, teachers, planners and anyone interested in solar energy and climatology. METEONORM includes data from 2400 meteorological stations worldwide. Version V4.0 is based on over 15 years in the development of meteorological databases for energy. It may be used for solar applications at any desired location in the world, as an interpolation model of solar radiation and additional parameters for any site in the world is included. Also, with up-to-date algorithms, solar radiation incident on surfaces of arbitrary orientation may be calculated at the touch of a button. The local skyline profile may be specified. Five languages are supported: English, French, German, Italian, Spanish. Sites may be selected on map by means of a graphical interface. User data may be imported. 16 different output formats are available. Data, programme, manual, maps and illustrations are incorporated on the CD-ROM which is available for sale

  13. Nonlinearity of the refractive index due to an excitonic molecule resonance state in CdS

    International Nuclear Information System (INIS)

    Baumert, R.; Broser, I.; Buschick, K.

    1986-01-01

    The authors report the observation of an intensity-dependent refractive-index nonlinearity in CdS due to a resonance state where an excitonic molecule is created by induced absorption of light. The refractive index n as a function of the incident laser photon energy E is measured directly by light refraction in thin crystal prisms. A renormalized dielectric function describes the measured n(E) spectra well. This strong refractive-index nonlinearity is well suited to produce an optical bistability and to further strengthen the evidence of CdS to be an important material for laser-induced dynamic gratings

  14. ROM a primera vista = ROM at first sight

    Directory of Open Access Journals (Sweden)

    Hugo Ricardo, D

    2006-09-01

    Full Text Available RESUMEN Objetivo:Es por todos conocida la importancia en la medición delROM (Range of motion: Rango de movimiento de una articulación, como elemento diagnóstico y evolutivo, pero, falta de uniformidad existe respecto a como debería ser registrado el ROM, de manera tal que otros profesionales pudieran interpretar los mismos resultados. Es objetivo de este trabajo, presentar una nueva técnica, rápida y eficaz para medir el ROM activo de las articulaciones de muñeca y dedos, sin necesidad de recurrir a un goniómetro o sistema similar.Material y métodos: La técnica se basa en darle a cada rango articular, desde la posición extrema, un valor máximo de 1 y un mínimo de 0 . Por ejemplo, si la extensión de muñeca es total, entonces corresponde valor 1; si la extensión de muñeca, no existe, entonces corresponde un valor de 0. Si la extensión llega a un 25% , se considera valor¼. Si la extensión llega a un 50%, se considera valor ½ .Si la extensión llega a un 75%, se considera valor ¾. Además, si al valor del ROM obtenido, le adosamos luego de un guión el valor 0, indicaráausencia de dolor. Si adosamos el valor 1, indicará presencia de dolor.Discusión: Esta técnica tiene evidentemente ciertas ventajas respecto a los métodos convencionales: Es más rápida, más cómoda, más simple, más fácil de aprender y recordar, y otros profesionales pueden apropiadamente interpretar los mismos resultados ABSTRACTObjective: we all are aware of the importance of the measuring of ROM in an articulation, as an element for diagnosis and evolution. Notwithstanding, there is a lack of uniformity concerning its registration to facilitate theinterpretation of the same results by other professionals.So that, the aim of this work is presenting a new, quick and effective technique to measure the active ROM of wrist and fingers joints without resorting to a goniometer or similar device.Material and methods: this technique consists of giving each

  15. Development of a CD-ROM on written language for the continuing education of elementary school teachers

    Directory of Open Access Journals (Sweden)

    Thaís dos Santos Gonçalves

    2011-12-01

    Full Text Available Distance education has emerged to minimize the anxiety of many professionals who need to update their knowledge, but do not have the time and opportunity to travel to educational centers. Objectives: To describe the development of a CD-ROM to provide distance continuing education to basic school teachers that addresses issues related to written language. Material and Methods: Previously, a script was developed with themes related to the acquisition and development of written language. Subsequently, a technical team transformed the texts in multimedia language. Results: The titles of each content area addressed are available on buttons and links. The files can be viewed in a linear sequence, allowing the teacher to start learning at the desired moment and go straight to the file that he or she wants to access. Videos that show practical applications of the concepts available in text are included. Conclusions: Brazil is a developing country. The use of technologies for education reduces cultural isolation among education professionals. It is necessary to focus on making teaching materials for distance education. In order to provide an effective learning environment, the learners reality should be considered. A multidisciplinary team should prepare the materials. The development of educational material for distance education on the acquisition and development of written language seems not only appropriate, but also warranted to provide professional growth opportunity for teachers who need time flexibility and/or live far away from academic centers.

  16. Wind Resource Atlas of Oaxaca (CD-ROM)

    Energy Technology Data Exchange (ETDEWEB)

    Elliott, D.; Schwartz, M.; Scott, G.; Haymes, S.; Heimiller, D.; George, R.

    2003-08-01

    The CD version of the Oaxaca Wind Resource Atlas, produced by the National Renewable Energy Laboratory's (NREL's) wind resource group, is the result of an extensive mapping study for the Mexican State of Oaxaca. This atlas identifies the wind characteristics and distribution of the wind resource in Oaxaca. The detailed wind resource maps and other information contained in the atlas facilitate the identification of prospective areas for use of wind energy technologies, both for utility-scale power generation and off-grid wind energy applications.

  17. Mid-term periodicities and heliospheric modulation of coronal index and solar flare index during solar cycles 22-23

    Science.gov (United States)

    Singh, Prithvi Raj; Saxena, A. K.; Tiwari, C. M.

    2018-04-01

    We applied fast Fourier transform techniques and Morlet wavelet transform on the time series data of coronal index, solar flare index, and galactic cosmic ray, for the period 1986-2008, in order to investigate the long- and mid-term periodicities including the Rieger ({˜ }130 to {˜ }190 days), quasi-period ({˜ }200 to {˜ }374 days), and quasi-biennial periodicities ({˜ }1.20 to {˜ }3.27 years) during the combined solar cycles 22-23. We emphasize the fact that a lesser number of periodicities are found in the range of low frequencies, while the higher frequencies show a greater number of periodicities. The rotation rates at the base of convection zone have periods for coronal index of {˜ }1.43 years and for solar flare index of {˜ }1.41 year, and galactic cosmic ray, {˜ }1.35 year, during combined solar cycles 22-23. In relation to these two solar parameters (coronal index and solar flare index), for the solar cycles 22-23, we found that galactic cosmic ray modulation at mid cut-off rigidity (Rc = 2.43GV) is anti-correlated with time-lag of few months.

  18. Formulating CdSe quantum dots for white light-emitting diodes with high color rendering index

    International Nuclear Information System (INIS)

    Li, Fei; Li, Wan-Nan; Fu, Shao-Yun; Xiao, Hong-Mei

    2015-01-01

    Generation of white light using CdSe quantum dots (QDs) alone presents exciting possibilities for solid state lighting technology. In this work, Cd(Ac) 2 ·2H 2 O and Na 2 SeSO 3 are used as precursors to synthesize CdSe-QDs with an average diameter ranging from 2.77 to 4.65 nm at the low temperature from 60 to 180 °C. Smaller CdSe-QDs with an average diameter of 2.29 nm are got by an oxidation etching process using H 2 O 2 as oxidant. The structural and optical properties of these QDs are investigated and proper formulation of CdSe QDs with various sizes is carefully designed to achieve white light with a high color rendering index (CRI). It is observed for the first time that the as-prepared white light-emitting diodes from single CdSe-QDs show the Commission Inernationale del’Eclairage coordinate (CIE) of (0.30,0.34) very close to that (0.33,0.33) of pure white light and a high CRI of 84. Owing to these advantages, the as-prepared white light-emitting diodes from a single compound are promising for lighting applications. - Highlights: • CdSe-quantum dots (QDs) with a continuously changing size from 2.31 to 4.74 nm are prepared. • The obtained CdSe-QDs emit lights with tunable colors in the whole visible range. • The obtained mixture sample generates white light with a high color rendering index of 84. • The sample yields white light with the CIE coordinate (0.30, 0.34) very close to that of pure white light

  19. Numerical Recipes in C++: The Art of Scientific Computing (2nd edn). Numerical Recipes Example Book (C++) (2nd edn). Numerical Recipes Multi-Language Code CD ROM with LINUX or UNIX Single-Screen License Revised Version

    International Nuclear Information System (INIS)

    Borcherds, P

    2003-01-01

    The two Numerical Recipes books are marvellous. The principal book, The Art of Scientific Computing, contains program listings for almost every conceivable requirement, and it also contains a well written discussion of the algorithms and the numerical methods involved. The Example Book provides a complete driving program, with helpful notes, for nearly all the routines in the principal book. The first edition of Numerical Recipes: The Art of Scientific Computing was published in 1986 in two versions, one with programs in Fortran, the other with programs in Pascal. There were subsequent versions with programs in BASIC and in C. The second, enlarged edition was published in 1992, again in two versions, one with programs in Fortran (NR(F)), the other with programs in C (NR(C)). In 1996 the authors produced Numerical Recipes in Fortran 90: The Art of Parallel Scientific Computing as a supplement, called Volume 2, with the original (Fortran) version referred to as Volume 1. Numerical Recipes in C++ (NR(C++)) is another version of the 1992 edition. The numerical recipes are also available on a CD ROM: if you want to use any of the recipes, I would strongly advise you to buy the CD ROM. The CD ROM contains the programs in all the languages. When the first edition was published I bought it, and have also bought copies of the other editions as they have appeared. Anyone involved in scientific computing ought to have a copy of at least one version of Numerical Recipes, and there also ought to be copies in every library. If you already have NR(F), should you buy the NR(C++) and, if not, which version should you buy? In the preface to Volume 2 of NR(F), the authors say 'C and C++ programmers have not been far from our minds as we have written this volume, and we think that you will find that time spent in absorbing its principal lessons will be amply repaid in the future as C and C++ eventually develop standard parallel extensions'. In the preface and introduction to NR

  20. Mawul Rom Project: Openness, obligation and reconciliation

    NARCIS (Netherlands)

    Brigg, M.; Tonnaer, A.A.C.

    2008-01-01

    Aboriginal Australian initiatives to restore balanced relationships with White Australians have recently become part of reconciliation efforts. This paper provides a contextualised report on one such initiative, the Mawul Rom cross-cultural mediation project. Viewing Mawul Rom as a diplomatic

  1. Review of Excavating Occaneechi Town: Archaeology of an Eighteenth-Century Indian Village in North Carolina. 1998, edited by R.P. Stephen Davis Jr., Patrick C. Livingood, Trawick Ward, and Vincas P. Steponaitis. University of North Carolina Press. ISBN 0-8078-6503-6 [CD-ROM

    Directory of Open Access Journals (Sweden)

    Jonathan Bateman

    1999-05-01

    Full Text Available The CD-ROM Excavating Occaneechi Town: Archaeology of an Eighteenth-Century Indian Village in North Carolina has become a familiar site on my desk in the last few months. Not, I admit, because I have been avidly scouring its content on a regular basis, but because I have been putting off writing this review. A wealth of information can be an intimidating thing.

  2. Development of an Integrated Approach to Routine Automation of Neutron Activation Analysis. Results of a Coordinated Research Project. Companion CD-ROM. Annex II: Country Reports

    International Nuclear Information System (INIS)

    2018-04-01

    Neutron activation analysis (NAA) is a powerful technique for determining bulk composition of major and trace elements. Automation may contribute significantly to keep NAA competitive for end-users. It provides opportunities for a larger analytical capacity and a shorter overall turnaround time if large series of samples have to be analysed. This publication documents and disseminates the expertise generated on automation in NAA during a coordinated research project (CRP). The CRP participants presented different cost-effective designs of sample changers for gamma-ray spectrometry as well as irradiation devices, and were able to construct and successfully test these systems. They also implemented, expanded and improved quality control and quality assurance as cross-cutting topical area of their automated NAA procedures. The publication serves as a reference of interest to NAA practitioners, experts, and research reactor personnel, but also to various stakeholders and users interested in basic research and/or services provided by NAA. This CD-ROM contains the individual country reports

  3. Comment scolariser les enfants Roms? Les enfants Roms dans les dispositifs mis en place à Bordeaux Métropole.

    OpenAIRE

    Øhlund, Ida

    2016-01-01

    Dans ce mémoire, je m intéresse à la scolarisation des enfants Roms en France. Je présente la place des enfants Roms dans la scolarisation en Europe et en France. Je discute les efforts qu on fait en France pour scolariser ces enfants, et je prends comme exemple les mesures d intégration prises par les autorités de Bordeaux Métropole en expliquant les rôles des différents acteurs locaux. Dans la première partie, j essaye de présenter le groupe minoritaire européen appelé « Rom ». J aborde l h...

  4. Periodicities observed on solar flux index (F10.7) during geomagnetic disturbances

    Science.gov (United States)

    Adhikari, B.; Narayan, C.; Chhatkuli, D. N.

    2017-12-01

    Solar activities change within the period of 11 years. Sometimes the greatest event occurs in the period of solar maxima and the lowest activity occurs in the period of solar minimum. During the time period of solar activity sunspots number will vary. A 10.7 cm solar flux measurement is a determination of the strength of solar radio emission. The solar flux index is more often used for the prediction and monitoring of the solar activity. This study mainly focused on the variation on solar flux index and amount of electromagnetic wave in the atmosphere. Both seasonal and yearly variation on solar F10.7 index. We also analyzed the dataset obatained from riometer.Both instruments show seasonal and yearly variations. We also observed the solar cycle dependence on solar flux index and found a strong dependence on solar activity. Results also show that solar intensities higher during the rising phase of solar cycle. We also observed periodicities on solar flux index using wavelet analysis. Through this analysis, it was found that the power intensities of solar flux index show a high spectral variability.

  5. The Cerefy registered clinical brain atlas on CD-ROM. Based on the classic Talairach-Tournoux and Schaltenbrand-Wahren brain atlases. 2. ed.

    International Nuclear Information System (INIS)

    Nowinski, W.L.; Thirunavuukarasuu, A.

    2001-01-01

    This remarkable CD-ROM provides enhanced and extended versions of three world-famous Thieme atlases, (Schaltenbrand and Wahren's Atlas for Stereotaxy of the Human Brain, Talairach and Tournoux's Co-Planar Stereotaxis Atlas of the Human Brain and Referentially Oriented Cerebral MRI Anatomy). It contains the electronic atlases as well as an easy navigation system to facilitate searching for and displaying more than 525 anatomical structures. Revolutionizing the field of brain anatomy, the authors have segmented, labeled, and cross referenced all the information contained in the books, and created contours for all three atlases. The Cerefy registered Clinical Brain Atlas now allows you to electronically navigate these atlases simultaneously on axial, coronal, and sagittal planes, and enjoy the ability to: 1. Access 210 high-quality, fully segmented, and labeled atlas images with corresponding contours, 2. Display and manipulate spatially co-registered atlases, 3. Dynamically label images with structure names and descriptions, and then highlight selected structures in the atlas image, 4. Image zoom in five different levels, mensurate, search, set triplanar, get coordinates, save, and print, 5. Access on-line help, glossary, and supportive atlas materials. (orig.)

  6. GeomarCD project; an educational CD-Rom about marine geophysics

    Science.gov (United States)

    Diaz, J.; Rubio, E.; Gómez, M.; Gallart, J.

    2009-04-01

    This project aims to introduce the main aspects of marine geophysics experiments to the high school students. We have chosen to present the information in the form an interactive game in which, taking care of the scientific objectives and the technological and logistic resources, the player must found the best strategy to make one of the 3 research projects proposed. Along the game, the player is introduced to the main aspects of the plate tectonics theory and the crustal structure as well as to the main methodologies available (seismics, potencial fields, cores). Rather than being based in theoretical aspects, largely covered by other outreach projects, this work focuses in how a realistic problem can be solved through a field experiment. The game takes place in the researcher's desk and in an oceanographic vessel as the BIO Hesperides and includes the choice of the research project, the design and development of the field work and the interpretation of the results. At the end, the player must complete a questionnaire to elaborate the final report. The correct choice of the appropriate methodologies and its interpretation is necessary to succeed. CD copies in Spanish are freely available upon request.

  7. Noziegums un sods Grama Svifta romānā "Dienas gaisma" un Fjodora Dostojevska romānā "Noziegums un sods"

    OpenAIRE

    Hohlova, Marija

    2008-01-01

    Šis bakalaura darbs pēta nozieguma un soda tēmu Fjodora Dostojevska romānā "Noziegums un sods" un Grema Svifta romānā "Dienas gaisma". Darbs sastāv no četrām nodaļām. Pirmajā nodaļā, kura pamatīgi aplūko nozieguma folozofiju, autore piemin integrēto pieeju nozieguma parādībai folozofijas skatījumā, kā arī analīzē nozieguma metafiziskās un socioloģiskās īpatnības uz Fjodora Dostojevska romāna "Noziegums un sods" pamata. Otrā nodaļa apraksta Fjodora Dostojevska romāna "Noziegums un sods" un Gre...

  8. Advances in Neutron Activation Analysis of Large Objects with Emphasis on Archaeological Examples. Results of a Coordinated Research Project. Annex II. Companion CD-ROM

    International Nuclear Information System (INIS)

    2018-03-01

    This publication is a compilation of the main results and findings of an IAEA coordinated research project (CRP). In particular, it discusses an innovative variation of neutron activation analysis (NAA) known as large sample NAA (LSNAA). There is no other way to measure the bulk mass fractions of the elements present in a large sample (up to kilograms in mass) non-destructively. Examples amenable to LSNAA include irregularly shaped archaeological artefacts, excavated rock samples, large samples of assorted ore, and finished products, such as nuclear reactor components. Advantages of LSNAA applications, limitations and scientific and technological requirements are described in this publication, which serves as a reference of interest not only to the NAA experts, research reactor personnel, and those considering this technique, but also to various stakeholders and users such as researchers, industrialists, environmental and legal experts, and administrators. The county reports given in this companion CD-ROM (Annex II) give a global overview of all the accomplishments achieved by the participants during the CRP. However, in several cases common procedures were employed by several participating laboratories, constituting one general approach.

  9. Electronic publishing of SPE papers

    International Nuclear Information System (INIS)

    Perdue, J.M.

    1992-01-01

    This paper reports that the SPE is creating an electronic index to over 25,000 technical papers and will produce a CD-ROM as an initial product. This SPE CD-ROM Masterdisc will be available at the SPE Annual Meeting in Washington, D.C. on October 4-7, 1992. The SPE Board has appointed an Ad Hoc Committee on Electronic Publishing to coordinate and oversee this project and to recommend authoring standards for submitting SPE papers electronically in the future

  10. Mid-term periodicities and heliospheric modulation of coronal index ...

    Indian Academy of Sciences (India)

    PRITHVI RAJ SINGH

    2018-03-06

    Mar 6, 2018 ... long-term periodicity of ∼11 years, with different solar activities. The physical processes that occur inside the. Sun are reflected by a periodic character in terms of coronal index of coronal emission (Fe XIV 530.3 nm) during solar activity cycles. Recently, a link between the strength of photospheric magnetic ...

  11. Reactive oxygen metabolites (ROMs) are associated with cardiovascular disease in chronic hemodialysis patients.

    Science.gov (United States)

    Bossola, Maurizio; Vulpio, Carlo; Colacicco, Luigi; Scribano, Donata; Zuppi, Cecilia; Tazza, Luigi

    2012-02-11

    The aim of our study was to measure reactive oxygen metabolites (ROMs) in chronic hemodialysis (HD) patients and evaluate the possible association with cardiovascular disease (CVD) and mortality. We measured ROMs in 76 HD patients and correlated with CVD, cardiovascular (CV) events in the follow-up and all-cause and CVD-related mortality. The levels of ROMs presented a median value of 270 (238.2-303.2) CARR U (interquartile range). We created a ROC curve (ROMs levels vs. CVD) and we identified a cut-off point of 273 CARR U. Patients with ROMs levels ≥273 CARR U were significantly older, had higher C-reactive protein levels and lower creatinine concentrations. The prevalence of CVD was higher in patients with ROMs levels ≥273 (87.1%) than in those with ROMs levels <273 CARR U (17.7%; p<0.0001). ROMs levels were significantly higher in patients with CVD (317±63.8) than in those without (242.7±49.1; p<0.0001). At multiple regression analysis, age, creatinine and C-reactive protein were independent factors associated with ROMs. At multiple logistic regression analysis the association between ROMs and CVD was independent (OR: 1.02, 95% CI: 1.00-1.05; p=0.03). Twenty six patients developed cardiovascular (CV) events during the follow-up. Of these, seven were in the group with ROMs levels <273 CARR U and 19 in the group with ROMs levels ≥273 CARR U. The logistic regression analysis showed that both age (OR: 1.06, 95% CI: 1.01-1.12; p=0.013) and ROMs levels (OR: 1.10, 95% CI: 1.00-1.02; p=0.045) were independently associated with CV events in the follow-up. ROMs are independently associated with CVD and predict CV events in chronic HD patients.

  12. The effects of neural mobilization on cervical radiculopathy patients' pain, disability, ROM, and deep flexor endurance.

    Science.gov (United States)

    Kim, Dong-Gyu; Chung, Sin Ho; Jung, Ho Bal

    2017-09-22

    Cervical radiculopathy (CR) is a disease of the cervical spine and a space-occupying lesion that occurs because of pathological problems with cervical nerve roots. Nerve root injury to produce functional disability. The purpose of this study was to examine the effects of neural mobilization with manual cervical traction (NMCT) compared with manual cervical traction (MCT) on pain, functional disability, muscle endurance, and range of motion (ROM) in individuals with CR patients. A blinded randomized clinical trial was conducted. Thirty CR patients were divided into two groups - those who received NMCT and those who received MCT. The intervention was applied three times per week for eight weeks. It was measured in order to determine the pain and functional disability in patients with CR. The numeric pain rating scale (NPRS), neck disability index (NDI), ROM, and deep flexor endurance of patients were measured prior to the experiment, four weeks, and eight weeks after the experiment to compare the time points. A repeated-measures analysis of variance was used to compare differences within each group prior to the experiment. And Bonferroni test was performed to examine the significance of each time point. There were significant differences within each group prior to the intervention, four weeks after the intervention, and eight weeks after the intervention in NPRS, NDI, ROM, and deep flexor endurance (Ppain relief, recovery from neck disability, ROM, and deep flexor endurance for patients with CR.

  13. Syd for Rom

    DEFF Research Database (Denmark)

    Frandsen, Steen Bo

    Bogen fortæller historien om et af Europas mest berømte vildnisser, De Pontinske Sumpe, der strakte sig i kystlandet umiddelbart syd for Rom fra romertiden til tørlægningen og forvandlingen til landbrugsland i 1930'erne. Allerede under romerne vandt sumpen uophørligt terræn og forvandlede det fla...

  14. FPGA Based Low Power ROM Design Using Capacitance Scaling

    DEFF Research Database (Denmark)

    Bansal, Meenakshi; Bansal, Neha; Saini, Rishita

    2015-01-01

    An ideal capacitor will not dissipate any power, but a real capacitor wil l have some power dissipation. In this work, we are going to design capacitance scaling based low power ROM design. In order to test the compatibility of this ROM design with latest i7 Processor, we are operating this ROM w...... in I/O Power, saving of 0.2% occur in Leakage Power, there will be a saving of 11.54% occur in Total Power. This design is implemented on Virtex-5 FPGA using Xilinx ISE and Verilog....

  15. Our God is Gold: Vlashika Rom at a Crossroads?

    Directory of Open Access Journals (Sweden)

    Andrš Zbyněk

    2016-12-01

    Full Text Available This article explicates the sociocultural dynamics in the changing lives of the Vlashika Rom group in the Czech and Slovak Republics and contemplates the prospective development of this Roma subculture. To provide a better insight into the endeavour of the Vlashika Rom to maintain their integrity and into their adaptation strategies, the author outlines the genesis of this subethnic group, pointing out the historical circumstances that have formed them in the past. Contrary to former descriptions, the author provides an entirely new concept for dividing the Vlashika Rom into subgroups, identifying three distinct levels that create social boundaries within this community. He describes the way of living of this subgroup in the past as well as the relationships between the Vlashika Rom and the dominant society. Frequently antagonistic, these relationships depend on their way of life, substantially determined by the way they earn their living. The author analyses the inner resources that keep sustaining the contemporary Vlashika Rom culture and, drawing on his own experience and impulses from literature, inquires how long this anachronistic yet at the same time very adaptable culture will be able to resist the assimilation pressures deriving from the very nature of the modern national state.

  16. A, B, CD, DVD: Marketing Higher Education to the Millennial Generation

    Science.gov (United States)

    Furbeck, Lee F.; Harding, Marc L.; Wohlgemuth, Darin R.; Bousquet, David R.

    2003-01-01

    Based on compelling financial and strategic reasons, Iowa State University replaced its paper viewbook with a CD-ROM digital viewbook following the Fall 1998 recruiting cycle. The first interactive DVD viewbook debuted for the Fall 2003 recruiting cycle, following a qualitative research study designed to gauge the effectiveness of the medium.…

  17. Near-Horizontal, Two-Phase Flow Patterns of Nitrogen and Hydrogen at Low Mass Heat and Flux (on CD-ROM)

    Science.gov (United States)

    VanDresar, N. T.; Siegwarth, J. D.

    2001-01-01

    One reason for NASA's interest in cryogenic two-phase flow with low mass and heat flux is the need to design spacecraft heat exchangers used for vaporizing cryogenic propellants. The CD-ROM provides digitized movies of particular flow patterns observed in experimental work. The movies have been provided in (QuickTime9Trademark) format, encoded at 320w x 240h pixels, 15 fps, using the Sorenson(Trademark) Video Codec for compression. Experiments were conducted to obtain data on the two-phase (liquid and vapor) flow behavior of cryogenic nitrogen and hydrogen under low mass and heat flux conditions. Tests were performed in normal gravity with a 1.5 degree up flow configuration. View ports in the apparatus permitted visual observation of the two-phase flow patterns. Computer codes to predict flow patterns were developed from theoretical/empirical models reported in the literature. Predictions from the computer codes were compared with experimental flow pattern observations. Results are presented employing the traditional two-dimensional flow pattern map format using the liquid and gas superficial velocities as coordinates. In general, the agreement between the experimental results and the analytical predictive methods is reasonably good. Small regions of the flow pattern maps are identified where the models are deficient as a result of neglecting phase change phenomena. Certain regions of the maps were beyond the range of the experiments and could not be completely validated. Areas that could benefit from further work include modeling of the transition from separated flow, collection of additional data in the bubble and annular flow regimes, and collection of experimental data at other inclination angles, tube diameters and high heat flux.

  18. [Benchmarking and other functions of ROM: back to basics].

    Science.gov (United States)

    Barendregt, M

    2015-01-01

    Since 2011 outcome data in the Dutch mental health care have been collected on a national scale. This has led to confusion about the position of benchmarking in the system known as routine outcome monitoring (rom). To provide insight into the various objectives and uses of aggregated outcome data. A qualitative review was performed and the findings were analysed. Benchmarking is a strategy for finding best practices and for improving efficacy and it belongs to the domain of quality management. Benchmarking involves comparing outcome data by means of instrumentation and is relatively tolerant with regard to the validity of the data. Although benchmarking is a function of rom, it must be differentiated form other functions from rom. Clinical management, public accountability, research, payment for performance and information for patients are all functions of rom which require different ways of data feedback and which make different demands on the validity of the underlying data. Benchmarking is often wrongly regarded as being simply a synonym for 'comparing institutions'. It is, however, a method which includes many more factors; it can be used to improve quality and has a more flexible approach to the validity of outcome data and is less concerned than other rom functions about funding and the amount of information given to patients. Benchmarking can make good use of currently available outcome data.

  19. Periodical rocking long period gratings in PANDA fibers for high temperature and refractive index sensing

    Science.gov (United States)

    Jin, Wa; Bi, Wei-hong; Fu, Xing-hu; Fu, Guang-wei

    2017-09-01

    We report periodical rocking long period gratings (PR-LPGs) in PANDA fibers fabricated with CO2 laser. The PR-LPGs achieve very high coupling efficiency of 19 dB with 12 periods and a 3.5° twist angle in just one scanning cycle, which is much more effective than the conventional CO2 laser fabrication technique. This type of LPGs exhibits polarization-selective resonance dips which demonstrate different sensitivities to environmental parameters. The high temperature and external refractive index sensitivities are measured simultaneously, so it can be used as a wavelength-selective polarization filter and sensor.

  20. A CD-ROM About Radiation Protection Aspects of a Nuclear Accident: Towards more Openness and Transparency

    International Nuclear Information System (INIS)

    Oudiz, Andre

    2003-01-01

    Many players are involved in managing a nuclear accident apart from radiation protection and nuclear safety experts. In an emergency response situation, the decision making process involves many non-technical players who nonetheless have a major role to play: in France these may include the 'Prefet', the emergency and civil defence services, the health services, the police, the 'gendarmerie' and local councillors, with advice from the safety and radiological protection authorities and expert evaluation organisations. Within the post-accident response, other players will be involved alongside those already described : professional bodies, particularly farming organisations, residents' associations, those responsible for environmental decontamination, agencies responsible for compensating victims, etc., etc. In both the short and the long-term phases of the crisis management process, it is essential to enable participants who may have very different -backgrounds and professional experience to work together with co-operation and mutual understanding. If non-technical players are to contribute effectively, there needs to be a minimum level of mutual understanding between them and the technical. players on what the nuclear risk really is and what is the rationale of the short and long term counter-measures aimed at protecting the public and restoring the contaminated environment. Local communities also need to share this basic understanding because their cooperation is required in order to implement the countermeasures properly. Conversely, if the experts are to advise the local authorities properly, they need to understand the criteria on which these local authorities and communities base their decisions: what psycho sociological factors apply, what logistical support is needed, what are the concerns of the local communities? The CD-ROM should help in gradually building up a shared interpretation or culture of the nuclear risk. This forum should promote debate that is

  1. SM-ROM-GL (Strong Motion Romania Ground Level Database

    Directory of Open Access Journals (Sweden)

    Ioan Sorin BORCIA

    2015-07-01

    Full Text Available The SM-ROM-GL database includes data obtained by the processing of records performed at ground level by the Romanian seismic networks, namely INCERC, NIEP, NCSRR and ISPH-GEOTEC, during recent seismic events with moment magnitude Mw ≥ 5 and epicenters located in Romania. All the available seismic records were re-processed using the same basic software and the same procedures and options (filtering and baseline correction, in order to obtain a consistent dataset. The database stores computed parameters of seismic motions, i.e. peak values: PGA, PGV, PGD, effective peak values: EPA, EPV, EPD, control periods, spectral values of absolute acceleration, relative velocity and relative displacement, as well as of instrumental intensity (as defined bz Sandi and Borcia in 2011. The fields in the database include: coding of seismic events, stations and records, a number of associated fields (seismic event source parameters, geographical coordinates of seismic stations, links to the corresponding ground motion records, charts of the response spectra of absolute acceleration, relative velocity, relative displacement and instrumental intensity, as well as some other representative parameters of seismic motions. The conception of the SM-ROM-GL database allows for an easy maintenance; such that elementary knowledge of Microsoft Access 2000 is sufficient for its operation.

  2. Fast computation of the Maslov index for hyperbolic linear systems with periodic coefficients

    International Nuclear Information System (INIS)

    Chardard, F; Dias, F; Bridges, T J

    2006-01-01

    The Maslov index is a topological property of periodic orbits of finite-dimensional Hamiltonian systems that is widely used in semiclassical quantization, quantum chaology, stability of waves and classical mechanics. The Maslov index is determined from the analysis of a linear Hamiltonian system with periodic coefficients. In this paper, a numerical scheme is devised to compute the Maslov index for hyperbolic linear systems when the phase space has a low dimension. The idea is to compute on the exterior algebra of the ambient vector space, where the Lagrangian subspace representing the unstable subspace is reduced to a line. When the exterior algebra is projectified the Lagrangian subspace always forms a closed loop. The idea is illustrated by application to Hamiltonian systems on a phase space of dimension 4. The theory is used to compute the Maslov index for the spectral problem associated with periodic solutions of the fifth-order Korteweg de Vries equation

  3. CdSe white quantum dots-based white light-emitting diodes with high color rendering index

    Science.gov (United States)

    Su, Yu-Sheng; Hsiao, Chih-Chun; Chung, Shu-Ru

    2016-09-01

    A white light emission CdSe quantum dots (QDs) can be prepared by chemical route under 180°C. An organic oleic acid (OA) is used to react with CdO to form Cd-OA complex. Hexadecylamine (HDA) and 1-Octadecene (ODE) were used as co-surfactants. By controlling the reaction time, a white light emission CdSe QDs can be obtained after reacts for 3 to 10 min. The luminescence spectra compose two obvious emission peaks and entire visible light ranges from 400 to 650 nm. Based on TEM measurement result, spherical morphologies with particle size 2.39+/-0.27 nm can be obtained. The quantum yields (QYs) of white CdSe QD are between 20 and 60 %, which depends on reaction time. A white CdSe QDs were mixed with UV cured gel (OPAS-226) with weight ratios 50.0 wt. %, and putted the mixture into reflective cup (3020, 13 mil) as convert type. The white LEDs have controllable CIE coordinates and correlated color temperature (CCT). The luminous efficacy of the device is less than 3 lm/W, but the color rendering index (CRI) for all devices are higher than 80. Since the luminous efficacy of hybrid devices has a direct dependence on the external QY of the UV-LED as well, the luminous efficacy can be improved by well dispersion of CdSe QDs in UV gel matrix and using optimized LED chips. Therefore, in this study, we provide a new and simple method to prepare high QY of white CdSe QDs and its have a potential to applicate in solid-state lighting.

  4. Proceedings of 2009 international congress on advances in nuclear power plants

    International Nuclear Information System (INIS)

    2009-01-01

    This CD-ROM is the collection of the paper presented at the 2009 International Congress on Advances in Nuclear Power Plants (ICAPP'09) . The 365 of the presented papers are indexed individually. (J.P.N.)

  5. Regional Ocean Modeling System (ROMS): CNMI

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Regional Ocean Modeling System (ROMS) 7-day, 3-hourly forecast for the region surrounding the Commonwealth of the Northern Mariana Islands (CNMI) at approximately...

  6. Regional Ocean Modeling System (ROMS): Samoa

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Regional Ocean Modeling System (ROMS) 7-day, 3-hourly forecast for the region surrounding the islands of Samoa at approximately 3-km resolution. While considerable...

  7. Regional Ocean Modeling System (ROMS): Guam

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Regional Ocean Modeling System (ROMS) 6-day, 3-hourly forecast for the region surrounding Guam at approximately 2-km resolution. While considerable effort has been...

  8. Regional Ocean Modeling System (ROMS): Oahu

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Regional Ocean Modeling System (ROMS) 7-day, 3-hourly forecast for the region surrounding the island of Oahu at approximately 1-km resolution. While considerable...

  9. Air University Library Index to Military Periodicals. Cumulative Issue January - December 1972. Volume 23, Number 4

    National Research Council Canada - National Science Library

    Rucks, Frances

    1972-01-01

    The Air University Library Index to Military Periodicals is a subject index to significant articles, news items and editorials appearing in 65 English language military and aeronautical periodicals...

  10. Air University Library Index to Military Periodicals. Cumulative Issue January-December 1980. Volume 31, Number 4

    National Research Council Canada - National Science Library

    Rucks, Frances

    1980-01-01

    The Air University Library Index to Military Periodicals is a subject index to significant articles, news items and editorials appearing in 73 English language military and aeronautical periodicals...

  11. Air University Library Index to Military Periodicals. Cumulative Issue January - December 1979. Volume 30, Number 4

    National Research Council Canada - National Science Library

    1979-01-01

    The Air University Library Index to Military Periodicals is a subject index to significant articles, news items and editorials appearing in 68 English language military and aeronautical periodicals...

  12. Air University Library Index to Military Periodicals. Cumulative Issue January - December 1985. Volume 36, Number 4

    National Research Council Canada - National Science Library

    Goodman, A

    1985-01-01

    The Air University Library Index to Military Periodicals is a subject index to significant articles, news items, and editorials appearing in 76 English language military and aeronautical periodicals...

  13. Air University Library Index to Military Periodicals. Cumulative Issue January - December 1982. Volume 33, Number 4

    National Research Council Canada - National Science Library

    Hatton, Jackie

    1982-01-01

    The Air University Library Index to Military Periodicals is a subject index to significant articles, news items, and editorials appearing in 76 English language military and aeronautical periodicals...

  14. Air University Library Index to Military Periodicals. Cumulative Issue January - December 1975. Volume 26, Number 4

    National Research Council Canada - National Science Library

    Rucks, Frances

    1975-01-01

    The Air University Library Index to Military Periodicals is a subject index to significant articles, news items and editorials appearing in 67 English language military and aeronautical periodicals...

  15. Air University Library Index to Military Periodicals. Cumulative Issue January-December 1981. Volume 32, Number 4

    National Research Council Canada - National Science Library

    1981-01-01

    The Air University Library Index to Military Periodicals is a subject index to significant articles, news items and editorials appearing in 72 English language military and aeronautical periodicals...

  16. Air University Library Index to Military Periodicals. Cumulative Issue January - December 1974. Volume 25, Number 4

    National Research Council Canada - National Science Library

    Rucks, Frances

    1974-01-01

    The Air University Library Index to Military Periodicals is a subject index to significant articles, news items and editorials appearing in 65 English language military and aeronautical periodicals...

  17. Air University Library Index to Military Periodicals. Cumulative Issue January-December 1978. Volume 29, Number 4

    National Research Council Canada - National Science Library

    Rucks, Frances

    1978-01-01

    The Air University Library Index to Military Periodicals is a subject index to significant articles, news items and editorials appearing in 68 English language military and aeronautical periodicals...

  18. Air University Library Index to Military Periodicals. Cumulative Issue January - December 1988. Volume 39, Number 4

    National Research Council Canada - National Science Library

    Adams, Emily

    1988-01-01

    The Air University Library Index to Military Periodicals is a subject index to significant articles, news items, and editorials appearing in 77 English language military and aeronautical periodicals...

  19. Status and trends of nuclear technologies - Report of the International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO). Additional information (Companion CD-ROM)

    International Nuclear Information System (INIS)

    2009-09-01

    The International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO) was launched in the year 2000, based on a resolution by the IAEA General Conference (GC(44)/RES/21). INPRO intends to help to ensure that nuclear energy is available in the 21st century in a sustainable manner, and seeks to bring together all interested Member States, both technology holders and technology users, to consider, jointly, actions to achieve desired innovations. INPRO is taking care of the specific needs of developing countries. This IAEA publication is part of Phase 1 of INPRO. It intends to provide an overview on history, present situation and future perspectives of nuclear fuel cycle technologies. While this overview focuses on technical issues, nevertheless, the aspects of economics, environment, and safety and proliferation resistance are important background issues for this study. After a brief description about the INPRO project and an evaluation of existing and future reactor designs the publication covers nuclear fuel cycle issues in detail. It is expected that this documentation will provide IAEA Member States and their nuclear engineers and designers, as well as policy makers with useful information on status and trends of future nuclear fuel cycle technologies. Due to the size of the full report it was decided to attach a CD-ROM in the back of the summary report

  20. Prediction of acute renal allograft rejection in early post-transplantation period by soluble CD30.

    Science.gov (United States)

    Dong, Wang; Shunliang, Yang; Weizhen, Wu; Qinghua, Wang; Zhangxin, Zeng; Jianming, Tan; He, Wang

    2006-06-01

    To evaluate the feasibility of serum sCD30 for prediction of acute graft rejection, we analyzed clinical data of 231 patients, whose serum levels of sCD30 were detected by ELISA before and after transplantation. They were divided into three groups: acute rejection group (AR, n = 49), uncomplicated course group (UC, n = 171) and delayed graft function group (DGF, n = 11). Preoperative sCD30 levels of three groups were 183 +/- 74, 177 +/- 82 and 168 +/- 53 U/ml, respectively (P = 0.82). Significant decrease of sCD30 was detected in three groups on day 5 and 10 post-transplantation respectively (52 +/- 30 and 9 +/- 5 U/ml respectively, P sCD30 values on day 5 post-transplantation (92 +/- 27 U/ml vs. 41 +/- 20 U/ml and 48 +/- 18 U/ml, P sCD30 levels on day 10 post-transplantation were virtually similar in patients of three groups (P = 0.43). Receiver operating characteristic (ROC) curve demonstrated that sCD30 level on day 5 post-transplantation could differentiate patients who subsequently suffered acute allograft rejection from others (area under ROC curve 0.95). According to ROC curve, 65 U/ml may be the optimal operational cut-off level to predict impending graft rejection (specificity 91.8%, sensitivity 87.1%). Measurement of soluble CD30 on day 5 post-transplantation might offer a noninvasive means to recognize patients at risk of impending acute graft rejection during early post-transplantation period.

  1. Accurate Computation of Periodic Regions' Centers in the General M-Set with Integer Index Number

    Directory of Open Access Journals (Sweden)

    Wang Xingyuan

    2010-01-01

    Full Text Available This paper presents two methods for accurately computing the periodic regions' centers. One method fits for the general M-sets with integer index number, the other fits for the general M-sets with negative integer index number. Both methods improve the precision of computation by transforming the polynomial equations which determine the periodic regions' centers. We primarily discuss the general M-sets with negative integer index, and analyze the relationship between the number of periodic regions' centers on the principal symmetric axis and in the principal symmetric interior. We can get the centers' coordinates with at least 48 significant digits after the decimal point in both real and imaginary parts by applying the Newton's method to the transformed polynomial equation which determine the periodic regions' centers. In this paper, we list some centers' coordinates of general M-sets' k-periodic regions (k=3,4,5,6 for the index numbers α=−25,−24,…,−1 , all of which have highly numerical accuracy.

  2. Correlations among visual analogue scale, neck disability index, shoulder joint range of motion, and muscle strength in young women with forward head posture.

    Science.gov (United States)

    Shin, Young Jun; Kim, Won Hyo; Kim, Seong Gil

    2017-08-01

    This study investigated the correlation between the neck disability index (NDI) and visual analogue scale (VAS), which are indicators of neck pain, shoulder joint range of motion (ROM), and muscle strength in women with a slight forward head posture. This study was carried out on 42 female college students attending Uiduk University in Gyeongju, Korea. The neck pain and disability index for each subject was measured using VAS and NDI, respectively. Two physiotherapists measured the shoulder joint ROM and muscle strengths of the subjects using a goniometer and a dynamometer, respectively. External rotation, internal rotation, and abduction of the shoulder joint were measured for each subject. A significant negative correlation between neck pain and shoulder joint ROM in external rotation and the muscle strength of the shoulder joint in abduction was found in the subjects. In addition, a significant positive correlation was observed between ROM in external rotation and muscle strength in abduction. This study showed a significant negative correlation between neck pain and ROM in external rotation as well as between neck pain and the muscle strength in abduction.

  3. BOREAS Level-3a Landsat TM Imagery: Scaled At-sensor Radiance in BSQ Format

    Science.gov (United States)

    Nickerson, Jaime; Hall, Forrest G. (Editor); Knapp, David; Newcomer, Jeffrey A.; Cihlar, Josef

    2000-01-01

    For BOREAS, the level-3a Landsat TM data, along with the other remotely sensed images, were collected in order to provide spatially extensive information over the primary study areas. This information includes radiant energy, detailed land cover, and biophysical parameter maps such as FPAR and LAI. Although very similar in content to the level-3s Landsat TM products, the level-3a images were created to provide users with a more usable BSQ format and to provide information that permitted direct determination of per-pixel latitude and longitude coordinates. Geographically, the level-3a images cover the BOREAS NSA and SSA. Temporally, the images cover the period of 22-Jun-1984 to 30-Jul-1996. The images are available in binary, image-format files. With permission from CCRS and RSI, several of the full-resolution images are included on the BOREAS CD-ROM series. Due to copyright issues, the images not included on the CD-ROM may not be publicly available. See Sections 15 and 16 for information about how to acquire the data. Information about the images not on the CD-ROMs is provided in an inventory listing on the CD-ROMs.

  4. Effect of probucol combined with atorvastatin adjuvant therapy on serum indexes of acute cerebral infarction patients during rehabilitation period

    Directory of Open Access Journals (Sweden)

    Li Zhang

    2016-06-01

    Full Text Available Objective: To analyze the effect of probucol combined with atorvastatin adjuvant therapy on serum indexes of acute cerebral infarction patients in rehabilitation period. Methods: A total of 102 patients with acute cerebral infarction were treated in our hospital from August 2011 to June 2015, were confirmed by magnetic resonance imaging and were randomly divided into observation group 51 cases and control group 51 cases according to the order of hospitalization. Control group received atorvastatin treatment alone, observation group received probucol combined with atorvastatin adjuvant therapy, and then differences in levels of serum CXCL16, HMGB1, CD40L and Fibulin-5, P-selectin, NPY, CGRP, visfatin and others, chemokines and inflammation-related factors, vascular endothelial cells and fibrinolytic function, etc were compared between two groups after treatment. Results: Serum CXCL16, HMGB1, CD40L and Fibulin-5 levels of observation group after treatment were lower than those of control group; serum P-selectin, NPY, visfatin, UCH-L1, sVCAM-1 and SAA levels of observation group after treatment were lower than those of control group while CGRP level was higher than that of control group; serum CCL-19, CCL-21, YKL-40, IL-33 and IL- 18 values of observation group after treatment were lower than those of control group; serum vWF, PAI-1 and plasminogen levels of observation group after treatment were lower than those of control group while 6-K-PGF1α and tPA levels were higher than those of control group. Conclusions: Probucol combined with atorvastatin adjuvant therapy for acute cerebral infarction patients in rehabilitation period can effectively optimize patients’ general status and avoid re-infarction in recovery period, and it has positive clinical significance.

  5. PERIODS OF VERTEBRAL COLUMN SENSITIVITY TO BORIC ACID TREATMENT IN CD-1 MICE IN UTERO

    Science.gov (United States)

    Periods of vertebral column sensitivity to boric acid treatment in CD-1 mice in utero.Cherrington JW, Chernoff N.Department of Toxicology, North Carolina State University, Raleigh, NC 27695, USA. jana_cherrington@hotmail.comBoric acid (BA) has many uses as...

  6. Management of waste from French nuclear fuel cycle: what are the key issues?

    International Nuclear Information System (INIS)

    Londres, V.; Do Quang, R.; FOURNIER, P.

    2001-01-01

    The publication on 2 CD-ROMs and includes 145 presentations delivered at the congress. In the work of the International Youth Nuclear Congress 2000 participated 288 young scientific works from over 30 countries. The address discusses the following sessions: Young Generation Session Nuclear Education and Transfer of Know-How; Nuclear Technology I; Political Aspects; Nuclear Technology II; Environment and Safety; Communication and Public Perception I; Communication and Public Perception II; Nuclear Programs and Technical Cooperation; Economics; Fuel Cycle Challenges. Each paper has been indexed separately. Before of full papers the first CD contains next chapters: Introduction (in 19 languages); General Information; Day by Day; Y-Notes Session Results; Sponsors; Media Album, and Conclusions. The second CD-ROM contains 28 minutes of video-film about programme of International Youth Nuclear Congress 2000. (authors)

  7. International Youth Nuclear Congress 2000: Youth, Future, Nuclear. Proceedings and Multimedia Presentation

    International Nuclear Information System (INIS)

    2001-01-01

    The publication on CD-ROM and includes 145 presentations delivered at the congress. In the work of the International Youth Nuclear Congress 2000 participated 288 young scientific works from over 30 countries. The address discusses the following sessions: Young Generation Session Nuclear Education and Transfer of Know-How; Nuclear Technology I; Political Aspects; Nuclear Technology II; Environment and Safety; Communication and Public Perception I; Communication and Public Perception II; Nuclear Programs and Technical Cooperation; Economics; Fuel Cycle Challenges. Each paper has been indexed separately. Before of full papers the first CD contains next chapters: Introduction (in 19 languages); General Information; Day by Day; Y-Notes Session Results; Sponsors; Media Album, and Conclusions. The second CD-ROM contains 28 minutes of video-film about programme of International Youth Nuclear Congress 2000

  8. HAEA NEPO tools used in nuclear emergency response

    International Nuclear Information System (INIS)

    Horvath, K.; Koblinger, L.

    2001-01-01

    The publication on 2 CD-ROMs and includes 145 presentations delivered at the congress. In the work of the International Youth Nuclear Congress 2000 participated 288 young scientific works from over 30 countries. The address discusses the following sessions: Young Generation Session Nuclear Education and Transfer of Know-How; Nuclear Technology I; Political Aspects; Nuclear Technology II; Environment and Safety; Communication and Public Perception I; Communication and Public Perception II; Nuclear Programs and Technical Cooperation; Economics; Fuel Cycle Challenges. Each paper has been indexed separately. Before of full papers the first CD contains next chapters: Introduction (in 19 languages); General Information; Day by Day; Y-Notes Session Results; Sponsors; Media Album, and Conclusions. The second CD-ROM contains 28 minutes of video-film about programme of International Youth Nuclear Congress 2000. (authors)

  9. Validation of accuracy and reliability of a simple measurement device for the lumber range of motion (SMD-L-ROM)

    International Nuclear Information System (INIS)

    Kato, Nakayuki; Fujiwara, Atsushi; Honda, Toshio; Taneichi, Hiroshi

    2007-01-01

    It is important to evaluate mobility of the lumbar spine for assessment of lumbar spinal disorders and their therapeutic effects. We developed a simple measurement device for the lumbar range of motion (SMD-L-ROM) which can be installed on the trunk. SMD-L-ROM allows to evaluate mobility of the lumbar spine without x-ray exposure. Accuracy and reliability of the measurement device was assessed in this article. SMD-L-ROM comprises two metallic immobilization plates (IPs) with a vertically installed bar and a rubber band for fixation of IP to the trunk. Two IPs were installed at the level of Th12 and the sacrum. Range of motion (ROM) of the lumbar spine was measured by using SMD-L-ROM and radiographic modalities (X-ray and CT). Consistency of the measured values by both of SMD-L-ROM and radiographic modalities was evaluated. Furthermore, inter- and intra-observer agreement of measured values by SMD-L-ROM was assessed. Regarding measurement of ROM, there was a high correlation between SMD-L-ROM and X-ray/CT especially in the sagittal and axial plane. There was no significant difference in the average values of ROM between the two methods. On the other hand, SMD-L-ROM did not detect accurate position of the lumbar spine in all dimensions. There were no inter- and intra-observer errors of measured values by SMD-L-ROM. ROM of the lumbar spine was simply and economically measured with SMD-L-ROM. Accuracy and reliability of SMD-L-ROM was good enough for ROM measurement in the lumbar spine. (author)

  10. Arquitectura románica en la provincia de Soria, 1856-2014. Marco historiográfico y metodológico

    Directory of Open Access Journals (Sweden)

    Lorenzo Arribas, Josemi

    2014-12-01

    Full Text Available The historiography of Romanesque in the province of Soria has three different stages. The former one begins with Eduardo Saavedra’s researches (1856 and it extends until 1934, when Gaya Nuño defends his PhD Thesis (La arquitectura románica en la provincia de Soria, which will not be published until 1946. The Spanish Civil War and the post-war period mark the beginning of the second stage, which is merely transitional, lacking any important contribution. The last stage begins with the publication of the three volumes of the Enciclopedia del Románico en Castilla y León (2002. These works have largely improved the knowledge of Romanesque architectural heritage, enhanced besides by the task undertaken by the technical office of the Cultural Project Soria Románica (2007- 2012, responsible for studying and restoring more than thirty Romanesque buildings in the Southern part of province. It is within this working frame that the building recording of the churches here presented must be understood. This historiographical assessment about provincial Romanesque does not include those buildings sited in the capital city, the Cathedral of El Burgo de Osma, the Monastery of Santa Maria de Huerta and the hermitage of San Baudelio (Casillas de Berlanga.La historiografía del Románico en la provincia de Soria tiene tres etapas diferenciadas. Una inicial, que parte de los estudios de Eduardo Saavedra (1856 y se extiende hasta 1934, fecha de la lectura de la tesis doctoral de Gaya Nuño (La arquitectura románica en la provincia de Soria, cuya publicación, no obstante, se demora hasta 1946. La Guerra Civil y posguerra marcan el comienzo de la segunda etapa, transicional y sin grandes aportaciones. La última etapa se inaugura con la publicación de los tres volúmenes sorianos de la Enciclopedia del Románico en Castilla y León (2002. Esta obra ha multiplicado el conocimiento del patrimonio edilicio románico, acrecentado, después, por la labor de la

  11. Environmental Sensitivity Index (ESI) Atlases: A sampling of digital data for geographic information systems, South Carolina, California, Hawaii, Oregon, Washington (NODC Accession 0046075)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This CD-ROM product from the NOAA National Ocean Service Hazardous Materials Response and Assessment Division contains a collection of Environmental Sensitivity...

  12. Periodic refractive index modifications inscribed in polymer optical fibre by focussed IR femtosecond pulses

    DEFF Research Database (Denmark)

    Stecher, Matthias; Williams, Robert J.; Bang, Ole

    Focussed femtosecond laser pulses were used to inscribe a periodic array of modifications in the core of a polymer optical fibre. Structural and refractive-index modifications have been observed at different pulse energies using DIC microscopy.......Focussed femtosecond laser pulses were used to inscribe a periodic array of modifications in the core of a polymer optical fibre. Structural and refractive-index modifications have been observed at different pulse energies using DIC microscopy....

  13. Christina Isajiw. Negotiating Human Rights: In Defence of Dissidents during the Soviet Era. A Memoir.

    Directory of Open Access Journals (Sweden)

    Barbara Martin

    2015-09-01

    Full Text Available Christina Isajiw. Negotiating Human Rights: In Defence of Dissidents during the Soviet Era. A Memoir. Edmonton and Toronto: Canadian Institute of Ukrainian Studies Press, 2014. xxx, 407 pp. Foreword by Bohdan Nahaylo. Introduction. Illustrations. Appendices on separate CD-Rom. Index. Paper.

  14. IDC Reengineering Phase 2 & 3 Rough Order of Magnitude (ROM) Cost Estimate Summary (Leveraged NDC Case).

    Energy Technology Data Exchange (ETDEWEB)

    Harris, James M.; Prescott, Ryan; Dawson, Jericah M.; Huelskamp, Robert M.

    2014-11-01

    Sandia National Laboratories has prepared a ROM cost estimate for budgetary planning for the IDC Reengineering Phase 2 & 3 effort, based on leveraging a fully funded, Sandia executed NDC Modernization project. This report provides the ROM cost estimate and describes the methodology, assumptions, and cost model details used to create the ROM cost estimate. ROM Cost Estimate Disclaimer Contained herein is a Rough Order of Magnitude (ROM) cost estimate that has been provided to enable initial planning for this proposed project. This ROM cost estimate is submitted to facilitate informal discussions in relation to this project and is NOT intended to commit Sandia National Laboratories (Sandia) or its resources. Furthermore, as a Federally Funded Research and Development Center (FFRDC), Sandia must be compliant with the Anti-Deficiency Act and operate on a full-cost recovery basis. Therefore, while Sandia, in conjunction with the Sponsor, will use best judgment to execute work and to address the highest risks and most important issues in order to effectively manage within cost constraints, this ROM estimate and any subsequent approved cost estimates are on a 'full-cost recovery' basis. Thus, work can neither commence nor continue unless adequate funding has been accepted and certified by DOE.

  15. Operating Experience with Nuclear Power Stations in Member States in 2011. 2012 Edition (CD-ROM)

    International Nuclear Information System (INIS)

    2012-08-01

    This CD contains the 43rd edition of the IAEA's series of annual reports on operating experience with nuclear power plants in Member States. It is a direct output from the IAEA's Power Reactor Information System (PRIS) and contains information on electricity production and overall performance of individual operational plants during 2011. In addition to annual information, the report contains a historical summary of performance during the lifetime of individual plants and figures illustrating worldwide performance of the nuclear industry. The CD contains also an overview of design characteristics and dashboards of all operating nuclear power plants worldwide.

  16. Responsiveness of the Shoulder Pain and Disability Index in patients with adhesive capsulitis

    Directory of Open Access Journals (Sweden)

    Juel Niels

    2008-12-01

    Full Text Available Abstract Background Instruments designed to measure the subjective impact of painful shoulder conditions have become essential in shoulder research. The Shoulder Pain and Disability Index (SPADI is one of the most extensively used scales of this type. The objective of this study was to investigate reproducibility and responsiveness of the SPADI in patients with adhesive capsulitis. Methods SPADI test-retest reproducibility was estimated by the "intraclass correlation coefficient" (ICC and the "smallest detectable difference" (SDD. Responsiveness was assessed by exploring baseline and follow-up data recorded in a recently reported clinical trial regarding hydrodilatation and corticosteroid injections in 76 patients with adhesive capsulitis. "Standardized response mean" (SRM and "reliable change proportion" (RCP for SPADI were compared with corresponding figures for shoulder range-of-motion (ROM. The relationship between SPADI and ROM change scores was investigated through correlation and linear regression analyses. Results Results for test-retest reproducibility indicated a smallest detectable difference of 17 points on the 0–100 scale, and an intraclass correlation coefficient of 0.89. The SPADI was generally more responsive than ROM. Weak to moderately strong associations were identified between SPADI and ROM change scores. According to the regression model, the three variables baseline SPADI, baseline active ROM and change in active ROM together explained 60% of the variance in SPADI improvement. Conclusion This study supports the use of SPADI as an outcome measure in similar settings.

  17. Frequency Adaptive Control Technique for Periodic Runout and Wobble Cancellation in Optical Disk Drives

    Directory of Open Access Journals (Sweden)

    Yee-Pien Yang

    2006-10-01

    Full Text Available Periodic disturbance occurs in various applications on the control of the rotational mechanical systems. For optical disk drives, the spirally shaped tracks are usually not perfectly circular and the assembly of the disk and spindle motor is unavoidably eccentric. The resulting periodic disturbance is, therefore, synchronous with the disk rotation, and becomes particularly noticeable for the track following and focusing servo system. This paper applies a novel adaptive controller, namely Frequency Adaptive Control Technique (FACT, for rejecting the periodic runout and wobble effects in the optical disk drive with dual actuators. The control objective is to attenuate adaptively the specific frequency contents of periodic disturbances without amplifying its rest harmonics. FACT is implemented in a plug-in manner and provides a suitable framework for periodic disturbance rejection in the cases where the fundamental frequencies of the disturbance are alterable. It is shown that the convergence property of parameters in the proposed adaptive algorithm is exponentially stable. It is applicable to both the spindle modes of constant linear velocity (CLV and constant angular velocity (CAV for various operation speeds. The experiments showed that the proposed FACT has successful improvement on the tracking and focusing performance of the CD-ROM, and is extended to various compact disk drives.

  18. Intertekstualitāte Dž.K. Roulingas "Harija Potera" romānu serijā

    OpenAIRE

    Strunga-Raude, Aija

    2009-01-01

    Šī bakalaura darba tēma ir „Intertekstualitāte Dž. K. Roulingas "Harija Potera" romānu sērijā”. Es izvēlējos šo tēmu, jo 2008. gadā tika izdota pēdējā septītā grāmata šajā romānu sērijā un šīs grāmatas jau ir izraisījušas plašas diskusijas dažādās sabiedrības grupās. Šī ir lieliska iespēja izpētīt ko tieši Džoanna Ketlīna Roulinga ir izmantojusi savā romānā “Harijs Poters”. Šī darba mērķis ir ilustrēt kā Dž. K. Roulinga, rakstot „Harija Potera” romānu sēriju, ir izmantojusi intertekstualit...

  19. Combination of VP3 and CD147-knockdown enhance apoptosis and tumor growth delay index in colorectal tumor allograft

    International Nuclear Information System (INIS)

    Ismail, Ruzila; Allaudin, Zeenathul Nazariah; Abdullah, Rasedee; Mohd Lila, Mohd-Azmi; Rahman, Nik-Mohd-Afizan Nik Abd.; Abdul Rahman, Sheikh-Omar

    2016-01-01

    Cancer therapies that kill cancer cells without affecting normal cells is the ultimate mode of treating cancers. The VP3, an avian virus-derived protein, can specifically initiate cell death through several signal transduction pathways leading to apoptosis. In cancer, chemoresistance and cell survivability implicate the cell surface protein, CD147. In this study, transfection of VP3 and silencing of CD147 genes was achieved through the treatment of tumors with pVIVO1-GFP/VP3 (VP3), psiRNA-CD147/2 (shCD147/2), and their combination of CT26 colon cancer cell-induced in mice. The effectiveness of tumor-treatment was ascertained by electrophoresis, TUNEL assay, and flow cytometry analysis. While histopathological and biochemical analysis were used as toxic side effect identification. The tumor growth delay index (TGDI) after treatment with VP3, shCD147/2, and their combination treatments increased by 1.3-, 1.2-, 2.0- and 2.3-fold respectively, over untreated control. The VP3-shCD147/2 combination treatment was more efficacious then either VP3 or shCD147/2 alone in the retardation of mouse CT26 colorectal cell tumor allograft. The antitumor effect of the combination treatment is the result of synergistic effects of VP3 and shCD147/2 on the tumor cells resulting in apoptosis. Thus, the study shows that combination of VP3 and shCD147/2 treatment can be developed into a potential approach for anticolorectal cancer treatment regimen. The online version of this article (doi:10.1186/s12885-016-2530-8) contains supplementary material, which is available to authorized users

  20. Regional Ocean Modeling System (ROMS): Main Hawaiian Islands

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Regional Ocean Modeling System (ROMS) 7-day, 3-hourly forecast for the region surrounding the main Hawaiian islands at approximately 4-km resolution. While...

  1. Regional Ocean Modeling System (ROMS): CNMI: Data Assimilating

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Regional Ocean Modeling System (ROMS) 3-day, 3-hourly data assimilating hindcast for the region surrounding the Commonwealth of the Northern Mariana Islands (CNMI)...

  2. Proceedings of the distribution automation seminar. CD-ROM ed.

    International Nuclear Information System (INIS)

    2003-01-01

    Electric utilities are being driven to improve the utilization of their distribution system assets while reducing life cycle costs. This seminar provided an opportunity for electric utilities to share their experience and knowledge about the constantly evolving technologies that apply to distributed automation. Customers and their representatives place increased priority on regulatory commissions to achieve reliability and push the conventional use of distribution automation into rural areas. Various options are under consideration by managers to incorporate a variety of distributed generation resources. Several papers highlighted technical aspects as they relate to applications to meet the changing needs of utilities. The latest products and technologies in the field were on display. The seminar sessions included: business cases; utility experience and applications; utility experience and projects; and, technology and equipment. Eight presentations were indexed separately for inclusion in this database

  3. How can journal impact factors be normalized across fields of science? An assessment in terms of percentile ranks and fractional counts

    NARCIS (Netherlands)

    Leydesdorff, L.; Zhou, P.; Bornmann, L.

    2013-01-01

    Using the CD-ROM version of the Science Citation Index 2010 (N = 3,705 journals), we study the (combined) effects of (a) fractional counting on the impact factor (IF) and (b) transformation of the skewed citation distributions into a distribution of 100 percentiles and six percentile rank classes

  4. Regional Ocean Modeling System (ROMS): Samoa: Data Assimilating

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Regional Ocean Modeling System (ROMS) 3-day, 3-hourly data assimilating hindcast for the region surrounding the islands of Samoa at approximately 3-km resolution....

  5. Regional Ocean Modeling System (ROMS): Oahu: Data Assimilating

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Regional Ocean Modeling System (ROMS) 2-day, 3-hourly data assimilating hindcast for the region surrounding the island of Oahu at approximately 1-km resolution....

  6. Propagation Properties of Airy Beam through Periodic Slab System with Negative Index Materials

    Directory of Open Access Journals (Sweden)

    Long Jin

    2018-01-01

    Full Text Available Based on light transfer matrix and electric field vector equation, the evolution of Airy beam propagating in periodic slab system with three negative index materials (NIMs and its transmission mechanism are investigated. The intensity profiles on emergent surface of periodic slab system and side view of Airy beam propagating in each right handed material (RHM and double negative material (DNM unit including lossless and losses DNMs are discussed. It is revealed that the self-recovery Airy beam can be achieved in long distance by using lossless periodic slab system as long as the negative refractive index nl=-nr and each unit length L=Z. As to losses slab system contained DNMs, the smaller the collision frequencies are, the better the Airy beam quality is formed. It is expected that the proposed manner of beam transmission and corresponding conclusions can be useful for extension applications of optical control, especially for optical communication and optical encryption technique.

  7. A. Moerdijk en R. Tempelaars (redactie). Van A tot Z en verder ...

    African Journals Online (AJOL)

    rbr

    op CD-ROM en elektroniese databasisse as redes vir sy optimistiese toekoms- perspektief. Volgens Moerdijk kan die leemtes wat in die gedrukte weergawe van die. WNT voorkom, aangevul word met die elektroniese weergawe wat in 1995 op. CD-ROM verskyn het. Deur gebruik te maak van die CD-ROM is aanvullende.

  8. Regional Ocean Modeling System (ROMS): Oahu South Shore

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Regional Ocean Modeling System (ROMS) 2-day, 3-hourly forecast for the region surrounding the south shore of the island of Oahu at approximately 200-m resolution....

  9. Between Freedom and Constraint: ROM Hacking of Pokémon Games

    OpenAIRE

    Barnabé, Fanny

    2018-01-01

    This paper aims to study a creative practice widespread in video game cultures: “ROM hacking”. By examining with the tools of rhetoric a defined corpus of ROM hacks derived from 『Pokémon』 games, the presentation will show that the formal construction of these derivative works demonstrates less a free or subversive transformation than a fairly strict respect for the original games’ conventions. By reproducing the structure of official 『Pokémon 』games, these fan productions become mirrors revea...

  10. Weight gain in different periods of pregnancy and offspring's body mass index at 7 years of age

    DEFF Research Database (Denmark)

    Andersen, Camilla Schou; Gamborg, Michael; Sørensen, Thorkild I A

    2011-01-01

    We investigated how average weekly gestational weight gain rates during three periods of pregnancy were related to the offspring's body mass index (BMI) at 7 years of age.......We investigated how average weekly gestational weight gain rates during three periods of pregnancy were related to the offspring's body mass index (BMI) at 7 years of age....

  11. Lunar and Planetary Science XXXII

    Science.gov (United States)

    2001-01-01

    This CD-ROM publication contains the extended abstracts that were accepted for presentation at the 32nd Lunar and Planetary Science Conference held at Houston, TX, March 12-16, 2001. The papers are presented in PDF format and are indexed by author, keyword, meteorite, program and samples for quick reference.

  12. Development and Utilization of Regional Oceanic Modeling System (ROMS) & Delicacy, Imprecision, and Uncertainty of Oceanic Simulations: An Investigation with ROMS

    Science.gov (United States)

    2010-09-30

    and Ecosystems: An important community use for ROMS is biogeochemisty: chemical cycles, water quality, blooms , micro-nutrients, larval dispersal... Chile current system. J. Climate, submitted. Colas, F., X. Capet, and J. McWilliams, 2010b: Mesoscale eddy buoyancy flux and eddy-induced

  13. Ģimene Mārgaretas Atvudas romānos

    OpenAIRE

    Voitiņa, Laura

    2009-01-01

    Mūsdienās diskusijas par ģimeni, tās vērtībām, mainīgo uzbūvi un problēmām, kas ietekmē šo institūtu, ir sastopamas ne tikai mutvārdu runā, bet arī rakstos. Dotā pētījuma mērķis bija veikt saturisku analīzi par ģimenes aprakstiem Margaretas Atvudas romānos “Istabenes Stāsts” un “Oriksa un Kreiks”, lai identificētu romānos aprakstītos ģimenes modeļus, vērtības, paražas un notikumus, kas ietekmē šo institūtu. Tika izmantotas gan teorētiskas, gan empīriskas pētījuma metodes. Lai sniegtu teorētis...

  14. Fabrication of highly luminescent InP/Cd and InP/CdS quantum dots

    International Nuclear Information System (INIS)

    Park, Jaehyun; Kim, Sunghoon; Kim, Sungwoo; Yu, Seung Tack; Lee, Bunyeoul; Kim, Sang-Wook

    2010-01-01

    Highly luminescent InP/Cd and InP/CdS core-shell QDs were fabricated by sequential addition of cadmium acetylacetonate and dodecanethiol to InP core solutions, which showed a red-shift in absorption and emission. ICP measurement revealed the existence of cadmium and TEM images showed the increased size of InP/CdS QDs. PXRD data identified zinc blend structures of InP and InP/CdS QDs, which indexed to the (1 1 1), (2 2 0) and (3 1 1) planes. The slight shift of peaks between InP and InP/CdS QDs can demonstrate the existence of CdS shell structures.

  15. En teoretisk utdyping av rom og materialitet som pedagogisk ressurs i barnehagen

    Directory of Open Access Journals (Sweden)

    Solveig Nordtømme

    2015-07-01

    Full Text Available Abstract: This article is a theoretical exploration with the aim of discussing an ontological basis for space and materiality as educational resources in kindergarten. Attention is directed on children’s play experiences interacting with space and materiality, and how children use and create space. The metaphors front stage, space in between, and backstage (inspired from Erving Goffman, 1969, which form the study's main findings, are used as the backdrop for the issue and analyzes. The empirical material used in this exploration has been collected with an ethnographic methodological approach in two kindergartens. Maurice Merleau-Ponty’s (1962 focus on bodily experience and presence in space, along with concepts from Latour’s (2005 actor-network theory, is used to explore the data. The article contributes with theoretical tools for professionals in kindergarten teaching, to shed light on the importance of space, materiality and play in children's everyday life in kindergarten.Sammendrag: Denne artikkelen diskuterer et ontologisk grunnlag og er en teoretisk utforskning av rom og materialitet som en pedagogisk ressurs i barnehagen. Oppmerksomheten er rettet mot barns lekeerfaringer i samspill med rom og materialitet, og hvordan barn bruker og skaper rom. Metaforene hovedrom, mellomrom, og bakrom (inspirert fra Erving Goffman, 1969, som danner studiens hovedfunn, blir brukt som et bakteppe for problemstilling og analyser av det empiriske materialet fra to barnehager. Maurice Merleau-Ponty publikasjoner The Phenomenology of Perception (Merleau-Ponty, 1962 med sitt fokus på kroppslig erfaring i levd rom, blir brukt sammen med begreper fra Latours aktør-nettverksteori (Latour 2005 til å utforske hvordan rom og materialitet kan være pedagogiske ressurser. Artikkelens kunnskapsbidrag er å presentere et teoretisk verktøy for barnehageprofesjonen og kunnskaper om lekens betydning i barns hverdag i barnehagen.

  16. Is there a role for rifampicin, ofloxacin and minocycline (ROM) therapy in the treatment of leprosy? Systematic review and meta-analysis.

    Science.gov (United States)

    Setia, Maninder S; Shinde, Santosh S; Jerajani, Hemangi R; Boivin, Jean-François

    2011-12-01

    A combination of rifampicin, ofloxacin and minocycline (ROM) is one of the newer recommendations for treatment of leprosy. We performed a systematic review and a meta-analysis of studies that had evaluated the efficacy of ROM therapy in treatment of paucibacillary and multibacillary leprosy patients. Studies were identified by searching the PubMed, Embase, LILACS and Cochrane databases. Data were abstracted from all relevant studies, and fixed effects models were used to calculate the summary estimate of effect in paucibacillary and multibacillary leprosy patients. Six studies comparing ROM therapy to multidrug therapy and eight studies that evaluated the effect of ROM therapy alone (no comparison group) were included in the review and meta-analysis. The combined estimate for single dose ROM vs. multidrug therapy in paucibacillary leprosy patients suggested that ROM was less effective than multidrug therapy in these patients [relative risk: 0.91, 95% confidence intervals (CI): 0.86-0.97]. However, the combined estimate for multiple doses of ROM vs. multidrug therapy in multibacillary leprosy patients suggested that ROM was as effective as multidrug therapy in reducing bacillary indices in these patients (proportion change: -4%, 95% CI -31% to 23%). No major side effects were reported in either the ROM or the multidrug treatment groups. Single-dose ROM therapy was less effective than multidrug therapy in paucibacillary patients. However, there are insufficient data to come to a valid conclusion on the efficacy of multidose ROM therapy in multibacillary leprosy, and additional studies with ROM therapy in multibacillary leprosy are needed. Furthermore, multiple doses may be considered as another alternative even for paucibacillary patients, and randomised controlled trials of this therapy may be useful to understand its contribution in the treatment and control of leprosy. © 2011 Blackwell Publishing Ltd.

  17. Calculation method of passive tracer using regional ocean modeling system (ROMS)

    International Nuclear Information System (INIS)

    Tubono, Takaki; Tsumune, Daisuke; Misumi, Kazuhiro; Yoshida, Yoshikatsu

    2010-01-01

    A dose assessments method for packages shipping radioactive materials was developed to calculate concentrations of radioactive materials discharged from the hypothetically sinking point using Regional Ocean Modeling System (ROMS). The programs of ROMS were improved for simultaneously calculating the flow fields around Japan and the concentrations discharged from several bottom points in the continental shelf. The model domain covered the northeast pacific region around Japan, 20degN-65degN, 120degE-165degE, with 1/10 degree horizontal resolution and 30 sigma-levels. The ROMS model captured main features such as Kuroshio currents, including the separation location and the Kuroshio extension, and Oyashio currents. The calculated volume transports through the main straits such as Tokara strait, Tsushima strait and Tsugaru strait were compared well to the measured or estimated that. The calculated concentrations discharged from 12 bottom points showed mixing associated with the eddies of ocean currents. This method is available to evaluate effectively the concentrations of radioactive materials only by setting the subsidence location and the concentrations and volume discharged. (author)

  18. Comparative Study of Periodical Literature Indexing: Print versus Electronic Access. Final Report.

    Science.gov (United States)

    Lowry, Charles B.

    This 2-year project at the University of Texas at Arlington (UTA) was conducted to determine the feasibility of providing online periodical indexing to the journal holdings of the UTA libraries by demonstrating an extended use of the libraries' NOTIS Online Public Access Catalog (OPAC) to provide better access to local resources. Three approaches…

  19. Influence of Body Mass Index on Sagittal Knee Range of Motion and Gait Speed Recovery 1-Year After Total Knee Arthroplasty.

    Science.gov (United States)

    Bonnefoy-Mazure, Alice; Martz, Pierre; Armand, Stéphane; Sagawa, Yoshimasa; Suva, Domizio; Turcot, Katia; Miozzari, Hermes H; Lübbeke, Anne

    2017-08-01

    The purpose of this prospective study was to investigate the influence of body mass index (BMI) on gait parameters preoperatively and 1 year after total knee arthroplasty (TKA). Seventy-nine patients were evaluated before and 1 year after TKA using clinical gait analysis. The gait velocity, the knee range of motion (ROM) during gait, their gains (difference between baseline and 1 year after TKA), the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), quality of life, and patient satisfaction were assessed. Nonobese (BMI gait speed and ROM gains. Adjustment was performed for gender, age, and WOMAC pain improvement. At baseline, gait velocity and knee ROM were significantly lower in obese compared with those in the nonobese patients (0.99 ± 0.27 m/s vs 1.11 ± 0.18 m/s; effect size, 0.53; P = .021; and ROM, 41.33° ± 9.6° vs 46.05° ± 8.39°; effect size, 0.52; P = .022). Univariate and multivariate linear regressions did not show any significant relation between gait speed gain or knee ROM gain and BMI. At baseline, obese patients were more symptomatic than nonobese (WOMAC pain: 36.1 ± 14.0 vs 50.4 ± 16.9; effect size, 0.9; P < .001), and their improvement was significantly higher (WOMAC pain gain, 44.5 vs 32.3; effect size, 0.59; P = .011). These findings show that all patients improved biomechanically and clinically, regardless of their BMI. Copyright © 2017 Elsevier Inc. All rights reserved.

  20. NODC Standard Product: International ocean atlas Volume 2 - Biological atlas of the Arctic Seas 2000 - Plankton of the Barents and Kara Seas (1 disc set) (NODC Accession 0098568)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Presented in this CD-ROM are physical and biological data for the region extending from the Barents Sea to the Kara Sea during 158 scientific cruises for the period...

  1. The Application of a Modified d-ROMs Test for Measurement of Oxidative Stress and Oxidized High-Density Lipoprotein

    Directory of Open Access Journals (Sweden)

    Fumiaki Ito

    2017-02-01

    Full Text Available Reactive oxygen species (ROS are involved in the initiation and progression of atherosclerosis. ROS-derived hydroperoxides, as an indicator of ROS production, have been measured by using the diacron reactive oxygen metabolites (d-ROMs test, which requires iron-containing transferrin in the reaction mixture. In this study we developed a modified d-ROMs test, termed the Fe-ROMs test, where iron ions were exogenously added to the reaction mixture. This modification is expected to exclude the assay variation that comes from different blood iron levels in individuals. In addition, this Fe-ROMs test was helpful for determining the class of plasma lipoproteins that are hydroperoxidized. Low-density lipoprotein/very low-density lipoprotein (LDL/VLDL and high-density lipoprotein (HDL were purified by use of an LDL/VLDL purification kit and the dextran sulfate-Mg2+ precipitation method, respectively; their hydroperoxide contents were assessed by performing the Fe-ROMs test. The majority of the hydroperoxides were detected only in the HDL fraction, not in the LDL/VLDL. Further detailed analysis of HDLs by size-exclusion high-performance liquid chromatography revealed that the hydroperoxide-containing molecules were small-sized HDLs. Because HDL was shown to be the principal vehicle for the plasma hydroperoxides, this Fe-ROMs test is a beneficial method for the assessment of oxidized-HDL levels. Indeed, Fe-ROMs levels were strongly associated with the levels of oxidized HDL, which were determined by performing the malondialdehyde-modified HDL enzyme immunoassay. In conclusion, the Fe-ROMs test using plasma itself or the HDL fraction after dextran sulfate-Mg2+ precipitation is useful to assess the functionality of HDL, because the oxidation of HDL impairs its antiatherogenic capacity.

  2. CD147-mediated chemotaxis of CD4+CD161+ T cells may contribute to local inflammation in rheumatoid arthritis.

    Science.gov (United States)

    Lv, Minghua; Miao, Jinlin; Zhao, Peng; Luo, Xing; Han, Qing; Wu, Zhenbiao; Zhang, Kui; Zhu, Ping

    2018-01-01

    CD161 is used as a surrogate marker for Th17 cells, which are implicated in the pathogenesis of rheumatoid arthritis (RA). In this study, we evaluated the percentage, clinical significance, and CD98 and CD147 expression of CD4 + CD161 + T cells. The potential role of CD147 and CD98 in cyclophilin A-induced chemotaxis of CD4 + CD161 + T cells was analyzed. Thirty-seven RA patients, 15 paired synovial fluid (SF) of RA, and 22 healthy controls were recruited. The cell populations and surface expression of CD98 and CD147 were analyzed by flow cytometry. Spearman's rank correlation coefficient and multiple linear regression were applied to calculate the correlations. Chemotaxis assay was used to investigate CD4 + CD161 + T cell migration. We found that the percentage of CD4 + CD161 + T cells and their expression of CD147 and CD98 in SF were higher than in the peripheral blood of RA patients. Percentage of SF CD4 + CD161 + T cells was positively correlated with 28-Joint Disease Activity Score (DAS28). CD147 monoclonal antibody (HAb18) attenuated the chemotactic ability of CD4 + CD161 + T cells. An increased CD4 + CD161 + T cell percentage and expression of CD147 and CD98 were shown in RA SF. Percentage of SF CD4 + CD161 + T cells can be used as a predictive marker of disease activity in RA. CD147 block significantly decreased the chemotactic index of CD4 + CD161 + cells induced by cyclophilin A (CypA). These results imply that the accumulation of CD4 + CD161 + T cells in SF and their high expression of CD147 may be associated with CypA-mediated chemotaxis and contribute to local inflammation in RA.

  3. Manufacturing process of rewritable CD and DVD; Kakikae gata CD, DVD no seizo process

    Energy Technology Data Exchange (ETDEWEB)

    Horie, M. [Mitsubishi Chemical Corp., Tokyo (Japan)

    1998-11-05

    Development of rewritable DVD is desired which has feedback compatibility with the existing players and ROM drives. The DVD is formed on a substrate with a thickness of 0.6 mm (dummy plate), and is composed of the multilayer film, i.e., protective coating made of UV hardening resin, reflective layer, dielectric protective layer, phase change type recording layer, and polycarbonate layer from the lower in order. A pair of dummy plates are pasted to enhance the mechanical strength, which has the same thickness of 1.2 mm as CD. Since the grooves and prepits are very fine, injection molding is more difficult compared with CD. Since a great stress change occurs during the formation and initialization processes of multilayer of phase change recording medium layer which is particular to DVD manufacturing process, control of warping is significant. Control of warping of the substrate is also significant, which affects the pasting and the whole process. The recording layer, dielectric protective layer and reflective layer are formed by the discharge spattering. The initialization is a particular process to the phase change medium. Complete non-recording state can be obtained by crystallizing the amorphous recording layer after the film formation. 3 figs.

  4. Adolescencia, relaciones románticas y actividad sexual: una revisión

    OpenAIRE

    Vargas Trujillo, Elvia; Barrera, Fernando

    2008-01-01

    Se presenta una revisión de algunas de las investigaciones más recientes sobre la adolescencia y los factores asociados a las relaciones románticas y la actividad sexual durante la adolescencia. Se parte de la premisa de que el análisis de la iniciación romántica y sexual durante la adolescencia requiere de modelos de causalidad múltiple que permitan dar cuenta, conjuntamente, de los factores que se encuentran en los contextos individual, familiar y social asociados con estos dos procesos. Se...

  5. Experimental study on x-rays dose enhancement effects for floating gate ROMs

    CERN Document Server

    Guo Hong Xia; Chen Yu Sheng; Han Fu Bin; He Chao Hui; Zhao Hui

    2002-01-01

    Experimental results of x-ray dose enhancement effects are given for floating gate read-only memory (ROMs) irradiated in the Beijing Synchrotron Radiation Facility. The wrong byte numbers vs. total irradiation dose have been tested and the equivalent relation of total dose damage is provided compared the response of devices irradiated with sup 6 sup 0 Co gamma-ray source. The x-ray dose enhancement factors for floating gate ROMs are obtained firstly in China. These results can be an effective evaluation data for x-rays radiation hardening technology

  6. The Periodic Table CD.

    Science.gov (United States)

    Banks, Alton J.; Holmes, Jon L.

    1995-01-01

    Describes the characteristics of the digitized version of The Periodic Table Videodisc. Provides details about the organization of information and access to the data via Macintosh and Windows computers. (DDR)

  7. Proyecto de un servicio funcional a prestar en una biblioteca universitaria: "El Servicio de Información Departamental" de la Biblioteca Max von Buch (Universidad de San Andrés

    Directory of Open Access Journals (Sweden)

    Moira Guppy

    2001-06-01

    Full Text Available Este trabajo -elaborado para el Seminario "La organización de los Servicios al Público en la Biblioteca" (UBA, 1998- describe el proyecto de un servicio a desarrollar en la Biblioteca Max von Buch de la Universidad de San Andrés. El "Servicio de Información Departamental" ofrecerá a los docentes e investigadores acceso a los recursos disponibles dentro de su área temática (Internet, bases de datos, índices de artículos de publicaciones periódicas, revistas en texto completo, series estadísticas, etc. Estará elaborado en dos formatos: un cd-rom actualizado periódicamente, y una página Web en línea especialmente diseñada. Con la implementación de este servicio se logrará un gran ahorro de tiempo en la búsqueda, análisis, tratamiento y difusión de la información destinada a la investigación académica.This paper -presented at the seminary "Public Services Organization at the Library"- describes a project to be developed at the Max von Buch Library, Universidad de San Andrés. The "Academic Information Service" would be design to provide access to researchers and faculty to all the resources available whithin each discipline and research area in the Internet, databases, periodical indexes, full text periodicals, statistical data, etc. They will gain access to it from a cd-rom which would be updated periodically, and a web page specially designed. The implementation of this project would provide faculty with qualified information along with considerable time saving in their researches.

  8. Proyecto de un servicio funcional a prestar en una biblioteca universitaria: “El Servicio de Información Departamental” de la Biblioteca Max von Buch (Universidad de San Andrés = Project of a functional service to be provided in an university library: "The Departmental Information Service" of the Max von Buch Library (Universidad de San Andrés

    Directory of Open Access Journals (Sweden)

    Moira Guppy

    2001-06-01

    Full Text Available Este trabajo –elaborado para el Seminario “La organización de los Servicios al Público en la Biblioteca” (UBA, 1998- describe el proyecto de un servicio a desarrollar en la Biblioteca Max von Buch de la Universidad de San Andrés. El “Servicio de Información Departamental” ofrecerá a los docentes e investigadores acceso a los recursos disponibles dentro de su área temática (Internet, bases de datos, índices de artículos de publicaciones periódicas, revistas en texto completo, series estadísticas, etc. Estará elaborado en dos formatos: un cd-rom actualizado periódicamente, y una página Web en línea especialmente diseñada. Con la implementación de este servicio se logrará un gran ahorro de tiempo en la búsqueda, análisis, tratamiento y difusión de la información destinada a la investigación académica = This paper –presented at the seminary “Public Services Organization at the Library”- describes a project to be developed at the Max von Buch Library, Universidad de San Andrés. The “Academic Information Service” would be design to provide access to researchers and faculty to all the resources available whithin each discipline and research area in the Internet, databases, periodical indexes, full text periodicals, statistical data, etc. They will gain access to it from a cd-rom which would be updated periodically, and a web page specially designed. The implementation of this project would provide faculty with qualified information along with considerable time saving in their researches.

  9. Oswestry Disability Index is a better indicator of lumbar motion than the Visual Analogue Scale.

    Science.gov (United States)

    Ruiz, Ferrin K; Bohl, Daniel D; Webb, Matthew L; Russo, Glenn S; Grauer, Jonathan N

    2014-09-01

    Lumbar pathology is often associated with axial pain or neurologic complaints. It is often presumed that such pain is associated with decreased lumbar motion; however, this correlation is not well established. The utility of various outcome measures that are used in both research and clinical practice have been studied, but the connection with range of motion (ROM) has not been well documented. The current study was performed to assess objectively the postulated correlation of lumbar complaints (based on standardized outcome measures) with extremes of lumbar ROM and functional ROM (fROM) with activities of daily living (ADLs) as assessed with an electrogoniometer. This study was a clinical cohort study. Subjects slated to undergo a lumbar intervention (injection, decompression, and/or fusion) were enrolled voluntarily in the study. The two outcome measures used in the study were the Visual Analogue Scale (VAS) for axial extremity, lower extremity, and combined axial and lower extremity, as well as the Oswestry Disability Index (ODI). Pain and disability scores were assessed with the VAS score and ODI. A previously validated electrogoniometer was used to measure ROM (extremes of motion in three planes) and fROM (functional motion during 15 simulated activities of daily living). Pain and disability scores were analyzed for statistically significant association with the motion assessments using linear regression analyses. Twenty-eight men and 39 women were enrolled, with an average age of 55.6 years (range, 18-79 years). The ODI and VAS were associated positively (p<.001). Combined axial and lower extremity VAS scores were associated with lateral and rotational ROM (p<.05), but not with flexion/extension or any fROM. Similar findings were noted for separately analyzed axial and lower extremity VAS scores. On the other hand, the ODI correlated inversely with ROM in all planes, and fROM in at least one plane for 10 of 15 ADLs (p<.05). Extremes of lumbar motion and

  10. Regional Ocean Modeling System (ROMS): Main Hawaiian Islands: Data Assimilating

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — Regional Ocean Modeling System (ROMS) 3-day, 3-hourly data assimilating hindcast for the region surrounding the main Hawaiian islands at approximately 4-km...

  11. Tidal simulation using regional ocean modeling systems (ROMS)

    Science.gov (United States)

    Wang, Xiaochun; Chao, Yi; Li, Zhijin; Dong, Changming; Farrara, John; McWilliams, James C.; Shum, C. K.; Wang, Yu; Matsumoto, Koji; Rosenfeld, Leslie K.; hide

    2006-01-01

    The purpose of our research is to test the capability of ROMS in simulating tides. The research also serves as a necessary exercise to implement tides in an operational ocean forecasting system. In this paper, we emphasize the validation of the model tide simulation. The characteristics and energetics of tides of the region will be reported in separate publications.

  12. Alois Riegl, Die Entstehung der Barockkunst in Rom, 1908

    NARCIS (Netherlands)

    Witte, A.; Bacchi, A.; Barroero, L.

    2017-01-01

    In 1908, Alois Riegl's unfinished text on the Italian Baroque was published by Max Dvorak and Arthur Burda; they edited part of his notes for three consecutive series of lectures at Vienna University. Riegl's book title aply reads Entstehung der Barockkunst in Rom: Akademische Vorlesungen and deals

  13. Implications of gluten exposure period, CD clinical forms, and HLA typing in the association between celiac disease and dental enamel defects in children. A case-control study.

    Science.gov (United States)

    Majorana, Alessandra; Bardellini, Elena; Ravelli, Alberto; Plebani, Alessandro; Polimeni, Antonella; Campus, Guglielmo

    2010-03-01

    The association between coeliac disease (CD) and dental enamel defects (DED) is well known. The aim of this study was to investigate the prevalence of DED in children with CD and to specifically find the association of DED and gluten exposure period, CD clinical forms, HLA class II haplotype. This study was designed as a matched case-control study: 250 children were enrolled (125 coeliac children - 79 female and 46 male, 7.2 +/- 2.8 years and 125 healthy children). Data about age at CD diagnosis, CD clinical form, and HLA haplotype were recorded. Dental enamel defects were detected in 58 coeliac subjects (46.4%) against seven (5.6%) controls (P < 0.005). We found an association between DED and gluten exposure period, as among CD subjects the mean age at CD diagnosis was significantly (P = 0.0004) higher in the group with DED (3.41 +/- 1.27) than without DED (1.26 +/- 0.7). DED resulted more frequent (100%) in atypical and silent CD forms than in the typical one (30.93%). The presence of HLA DR 52-53 and DQ7antigens significantly increased the risk of DED (P = 0.0017) in coeliac children. Our results confirmed a possible correlation between HLA antigens and DED.

  14. The noncommutative index theorem and the periodic table for disordered topological insulators and superconductors

    Science.gov (United States)

    Katsura, Hosho; Koma, Tohru

    2018-03-01

    We study a wide class of topological free-fermion systems on a hypercubic lattice in spatial dimensions d ≥ 1. When the Fermi level lies in a spectral gap or a mobility gap, the topological properties, e.g., the integral quantization of the topological invariant, are protected by certain symmetries of the Hamiltonian against disorder. This generic feature is characterized by a generalized index theorem which is a noncommutative analog of the Atiyah-Singer index theorem. The noncommutative index defined in terms of a pair of projections gives a precise formula for the topological invariant in each symmetry class in any dimension (d ≥ 1). Under the assumption on the nonvanishing spectral or mobility gap, we prove that the index formula reproduces Bott periodicity and all of the possible values of topological invariants in the classification table of topological insulators and superconductors. We also prove that the indices are robust against perturbations that do not break the symmetry of the unperturbed Hamiltonian.

  15. ROMS/TOMS Tangent Linear and Adjoint Models: Testing and Applications

    National Research Council Canada - National Science Library

    Miller, Arthur J; Cornuelle, Bruce D

    2004-01-01

    ... (Regional Ocean Modeling System/Terrain-Following Ocean Modeling System) that is suitable for general use by the ROMS/TOMS community and to develop computational platforms based on the TLM and ADM for 4D variational data assimilation (4DVar...

  16. The Correlation of Exercise and Range of Motion (ROM on Elderly Knee Observasional Study on Elderly People in Pedurungan Semarang

    Directory of Open Access Journals (Sweden)

    Adhitya Putra Widyantoro

    2012-06-01

    Design and Method: Observastional study with a cross sectional design 80 elderly men and women were divided into 2 groups: gymnastics group in the Social Rehabilitation Unit Of Pucang Gading (n=40 and unexcercises group in the Penggaron village (n=40. In both groups, the degree of ROM of knee was assessed using the Goniometer. To evaluate the value of its significance, the data were analyzed using the Mann Withney test followed by Spearmann’s rho test. Result: ROM for gymnastic(exercised group and unexercised group were 115.50°±11.591°, 95.38°±12.780° respectively with p<0. 001. Resuts showed that doing exercise was useful for maintaining ROM of knee in elderly people. Spearmann’s rho test resulted in a strong correlation between ROM and exercise with r value of 0.652. Conclusion: exercise correlates with ROM of knee in elderly (Sains Medika, 4(1:39-45.

  17. NODC Standard Product: Atlas of surface marine data 1994 (9 disc set) (NCEI Accession 0101474)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — A set of 9 CD-ROMs were produced to accompany the analog publication Atlas of Surface Marine Data, 1994. Each CD-ROM contains monthly mean objectively analyzed...

  18. Development and Utilization of Regional Oceanic Modeling System (ROMS). Delicacy, Imprecision, and Uncertainty of Oceanic Simulations: An Investigation with the Regional Oceanic Modeling System (ROMS). Mixing in the Ocean Surface Layer Using the Regional Oceanic Modeling System (ROMS).

    Science.gov (United States)

    2011-09-30

    community use for ROMS is biogeochemisty: chemical cycles, water quality, blooms , micro-nutrients, larval dispersal, biome transitions, and coupling to...J.C. McWilliams, X. Capet, and J. Kurian, 2010: Heat balance and eddies in the Peru- Chile Current System. Climate Dynamics, 37, in press. doi10.1007

  19. Biblioteca Naţională a României: obiective şi perspective în valorificarea patrimoniului cultural

    Directory of Open Access Journals (Sweden)

    Elena Tîrziman

    2008-01-01

    Biblioteca Naţională a României este implicată în proiecte internaţionale care au ca scop crearea de conţinut digital relevant pentru memoria culturală europeană: The European Library – TEL (Biblioteca europeană, Manuscriptorium şi ENRICH – European Networking Resources and Information concerning Cultural Heritage, proiecte coordonate de Biblioteca Naţională a Cehiei. Biblioteca Naţională a României a contribuit la proiectele Manuscriptorium / ENRICH prin carte românească veche din perioada corespunzătoare secolelor XVI-XVII.

  20. Index of CD34+ Cells and Mononuclear Cells in the Bone Marrow of Spinal Cord Injury Patients of Different Age Groups: A Comparative Analysis

    Directory of Open Access Journals (Sweden)

    Vidyasagar Devaprasad Dedeepiya

    2012-01-01

    Full Text Available Introduction. Recent evidence of safety and efficacy of Bone Marrow Mononuclear Cells (BMMNC in spinal cord injury makes the Bone Marrow (BM CD34+ percentage and the BMMNC count gain significance. The indices of BM that change with body mass index and aging in general population have been reported but seldom in Spinal Cord Injury (SCI victims, whose parameters of relevance differ from general population. Herein, we report the indices of BMMNC in SCI victims. Materials and Methods. BMMNCs of 332 SCI patients were isolated under GMP protocols. Cell count by Trypan blue method and CD34+ cells by flow cytometry were documented and analysed across ages and gender. Results. The average BMMNC per ml in the age groups 0–20, 21–40, 41–60, and 61–80 years were 4.71, 4.03, 3.67, and 3.02 million and the CD34+ were 1.05%, 1.04%, 0.94%, and 0.93% respectively. The decline in CD34+ was sharp between 20–40 and 40–60 age groups. Females of reproductive age group had lesser CD34+. Conclusion. The BMMNC and CD34+ percentages decline with aging in SCI victims. Their lower values in females during reproductive age should be analysed for relevance to hormonal influence. This study offers reference values of BMMNC and CD34+ of SCI victims for successful clinical application.

  1. Geology and resource assessment of Costa Rica at 1:500,000 scale; a digital representation of maps of the U.S. Geological Survey's 1987 folio I-1865

    Science.gov (United States)

    Schruben, Paul G.

    1997-01-01

    This CD-ROM contains digital versions of the geology and resource assessment maps of Costa Rica originally published in USGS Folio I-1865 (U.S. Geological Survey, the Direccion General de Geologia, Minas e Hidrocarburos, and the Universidad de Costa Rica, 1987) at a scale of 1:500,000. The following layers are available on the CD-ROM: geology and faults; favorable domains for selected deposit types; Bouguer gravity data; isostatic gravity contours; mineral deposits, prospects, and occurrences; and rock geochemistry sample points. For DOS users, the CD-ROM contains MAPPER, a user-friendly map display program. Some of the maps are also provided in the following additional formats on the CD-ROM: (1) ArcView 1 and 3, (2) ARC/INFO 6.1.2 Export, (3) Digital Line Graph (DLG) Optional, and (4) Drawing Exchange File (DXF.)

  2. An exploration of advanced X-divertor scenarios on ITER

    Science.gov (United States)

    Covele, B.; Valanju, P.; Kotschenreuther, M.; Mahajan, S.

    2014-07-01

    It is found that the X-divertor (XD) configuration (Kotschenreuther et al 2004 Proc. 20th Int. Conf. on Fusion Energy (Vilamoura, Portugal, 2004) (Vienna: IAEA) CD-ROM file [IC/P6-43] www-naweb.iaea.org/napc/physics/fec/fec2004/datasets/index.html, Kotschenreuther et al 2006 Proc. 21st Int. Conf. on Fusion Energy 2006 (Chengdu, China, 2006) (Vienna: IAEA), CD-ROM file [IC/P7-12] www-naweb.iaea.org/napc/physics/FEC/FEC2006/html/index.htm, Kotschenreuther et al 2007 Phys. Plasmas 14 072502) can be made with the conventional poloidal field (PF) coil set on ITER (Tomabechi et al and Team 1991 Nucl. Fusion 31 1135), where all PF coils are outside the TF coils. Starting from the standard divertor, a sequence of desirable XD configurations are possible where the PF currents are below the present maximum design limits on ITER, and where the baseline divertor cassette is used. This opens the possibility that the XD could be tested and used to assist in high-power operation on ITER, but some further issues need examination. Note that the increased major radius of the super-X-divertor (Kotschenreuther et al 2007 Bull. Am. Phys. Soc. 53 11, Valanju et al 2009 Phys. Plasmas 16 5, Kotschenreuther et al 2010 Nucl. Fusion 50 035003, Valanju et al 2010 Fusion Eng. Des. 85 46) is not a feature of the XD geometry. In addition, we present an XD configuration for K-DEMO (Kim et al 2013 Fusion Eng. Des. 88 123) to demonstrate that it is also possible to attain the XD configuration in advanced tokamak reactors with all PF coils outside the TF coils. The results given here for the XD are far more encouraging than recent calculations by Lackner and Zohm (2012 Fusion Sci. Technol. 63 43) for the Snowflake (Ryutov 2007 Phys. Plasmas 14 064502, Ryutov et al 2008 Phys. Plasmas 15 092501), where the required high PF currents represent a major technological challenge. The magnetic field structure in the outboard divertor SOL (Kotschenreuther 2013 Phys. Plasmas 20 102507) in the recently created

  3. A sonographic lesion index for Crohn's disease helps monitor changes in transmural bowel damage during therapy.

    Science.gov (United States)

    Zorzi, Francesca; Stasi, Elisa; Bevivino, Gerolamo; Scarozza, Patrizio; Biancone, Livia; Zuzzi, Sara; Rossi, Carla; Pallone, Francesco; Calabrese, Emma

    2014-12-01

    Therapeutic antibodies against tumor necrosis factor α (anti-TNF) are effective in patients with Crohn's disease (CD). Mucosal healing is a surrogate marker of efficacy, but little is known about the effects of anti-TNF agents on structural damage in the intestine. Small-intestine contrast ultrasonography (SICUS) is a valuable tool for assessing CD lesions. A new sonographic quantitative index (the sonographic lesion index for CD [SLIC]) was developed to quantify changes in CD lesions detected by SICUS. We explored whether the SLIC can be used to monitor transmural bowel damage in CD patients during anti-TNF therapy. We performed a prospective study of 29 patients with ileal or ileocolonic CD treated with anti-TNF agents; patients underwent SICUS before and after scheduled induction and maintenance therapy. To determine whether changes that can be detected by SICUS occur independently of anti-TNF therapy, 7 patients with ileal CD treated with mesalamine were enrolled as controls. A clinical response was defined as steroid-free remission, with CD activity index scores less than 150. We observed significant improvements in SLIC scores and subscores after induction and maintenance therapy with anti-TNFs, compared with before therapy. SLIC scores and subscores and index classes were improved significantly in patients with vs without clinical responses. Controls had no improvements in terms of CD activity index or SLIC scores, or index classes. Sonographic assessment using the quantitative index SLIC can be used to monitor changes in transmural bowel damage during anti-TNF therapy for CD. Copyright © 2014 AGA Institute. Published by Elsevier Inc. All rights reserved.

  4. Dissection of a circulating CD3+ CD20+ T cell subpopulation in patients with psoriasis.

    Science.gov (United States)

    Niu, J; Zhai, Z; Hao, F; Zhang, Y; Song, Z; Zhong, H

    2018-05-01

    CD3 + CD20 + T cells are a population of CD3 + T cells that express CD20 and identified in healthy donors and autoimmune diseases. However, the nature and role of these cells in patients with psoriasis remain unclear. In this study, we aimed to investigate the level, phenotype, functional and clinical relevance of CD3 + CD20 + T cells in the peripheral blood of patients with psoriasis. We found that a small subset of CD3 + T cells expressed CD20 molecule in the peripheral blood of patients with psoriasis, and their levels were similar to those in healthy donors. Circulating CD3 + CD20 + T cells in patients with psoriasis were enriched in CD4 + cells and displayed an activated effector phenotype, as these cells contained fewer CD45RA + -naive and CCR7 + cells with increased activity than those of CD3 + T cells lacking CD20. In addition, compared with healthy donors, circulating CD3 + CD20 + T cells in patients with psoriasis produced more cytokines, interleukin (IL)-17A, tumour necrosis factor (TNF)-α and IL-21, but not IL-4 and IFN-γ. Furthermore, a significantly positive correlation was found between the levels of IL-17A, TNF-α and IL-21-production CD3 + CD20 + T cells with Psoriasis Area and Severity Index scores. Our findings suggest that CD3 + CD20 + T cells may play a role in the pathogenesis of psoriasis. © 2018 British Society for Immunology.

  5. A Community Terrain-Following Ocean Modeling System (ROMS)

    Science.gov (United States)

    2015-09-30

    funded NOPP project titled: Toward the Development of a Coupled COAMPS-ROMS Ensemble Kalman filter and adjoint with a focus on the Indian Ocean and the...surface temperature and surface salinity daily averages for 31-Jan-2014. Similarly, Figure 3 shows the sea surface height averaged solution for 31-Jan... temperature (upper panel; Celsius) and surface salinity (lower panel) for 31-Jan-2014. The refined solution for the Hudson Canyon grid is overlaid on

  6. Molecular Cloning, Expression and Characterization of Plasmid Encoding Rhomboid 4 (ROM4 of Tachyzoite of Toxoplasma gondii RH Strain

    Directory of Open Access Journals (Sweden)

    Mohammad Taghi RAHIMI

    2017-12-01

    Full Text Available AbstractBackground: The objective of this study was to clone, express and characterize the gene encoding rhomboid 4 (ROM4 proteins, a vital gene in surface adhesion and host cell invasion process of tachyzoite of T. gondii in an appropriate expression vector and eukaryotic cell for production of recombinant protein.Methods: Toxoplasma RNA was isolated from tachyzoites (RH strain and complementary DNA was synthesized. Oligonucleotide primer pair was designed based on Toxoplasma ROM4 gene sequence with XhoI and EcoRI restriction sites at 5´ end of forward and reverse primers, respectively. ROM4 gene was amplified by PCR, cloned into pTG19-T vector and the recombinant plasmid was sequenced. The gene was subcloned into pcDNA3 plasmid and expressed in CHO cells as eukaryotic cell. SDS-PAGE and western blotting were performed for protein determination and verification.Results: Cloning of ROM4 gene in pTG19-T vector was confirmed by colony-PCR and enzymatic digestion. The results of enzymatic digestion and gene sequencing confirmed successful cloning and subcloning procedures. The nucleotide sequence of the cloned ROM4 gene showed 99% homology compared to the corresponding sequences of original gene. SDS-PAGE and western blotting analyses of the purified protein revealed a single band having expected size of 65 kDa.Conclusion: This eukaryotic expression system is an appropriate system for high-level recombinant protein production of ROM4 gene from T. gondii tachyzoites used as antigenic component for serological assay and vaccine development.

  7. Reduced Number of CD8+ Cells in Tonsillar Germinal Centres in Children with the Periodic Fever, Aphthous Stomatitis, Pharyngitis and Cervical Adenitis Syndrome.

    Science.gov (United States)

    Førsvoll, J; Janssen, E A M; Møller, I; Wathne, N; Skaland, I; Klos, J; Kristoffersen, E K; Øymar, K

    2015-07-01

    The syndrome of periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA) is an autoinflammatory disorder of unknown aetiology. Tonsillectomy may cause a prompt resolution of the syndrome. The aim was to study the histologic and immunological aspects of the palatine tonsils in PFAPA, to help understand the pathophysiology of the syndrome. Tonsils from children with PFAPA (n = 11) and children with tonsillar hypertrophy (n = 16) were evaluated histologically after haematoxylin and eosin staining. The number of different cell types was identified immunohistochemically by cluster of differentiation (CD) markers: CD3 (T cells), CD4 (T helper cells), CD8 (cytotoxic T cells), CD15 (neutrophils), CD20 (B cells), CD45 (all leucocytes), CD57 (NK cells) and CD163 (monocytes and macrophages). Tonsils from children with PFAPA showed reactive lymphoid hyperplasia dominated by well-developed germinal centres with many tingible body macrophages. The histologic findings were unspecific, and a similar morphologic appearance was also found in the tonsils from controls. The number of CD8+ cells in germinal centres differed between children with PFAPA [median 9 cells (quartiles: 5, 15)] and controls [18 cells (12, 33) (P = 0.001)] and between children with PFAPA with (median 14 cells; 9, 16) and without (4 cells; 3, 8) aphthous stomatitis (P = 0.015). For the other cell types, no differences in germinal centres were found between children with PFAPA and controls. In conclusion, a lower number of CD8+ cells were found in germinal centres of tonsils in children with PFAPA compared to controls, which may be a feature linked to the aetiology of the syndrome. © 2015 John Wiley & Sons Ltd.

  8. Uudiseid ja meeldetuletusi raamatukogult / Karin Tulve

    Index Scriptorium Estoniae

    Tulve, Karin

    2000-01-01

    2000. aastast on TPÜ raamatukokku ostetud EBSCO online andmebaasid, augustist on võimalik kasutada referaat- ja täistekstandmebaasi Academic Search FullText International 15 CD-ROM-il ja septembrist humanitaarteaduste bibliograafilist andmebaasi Sophia : European Databases in the Humanities CD-ROM-il

  9. NODC Standard Product: International ocean atlas Volume 11 - Climatic atlas of the Sea of Azov 2008 (1 disc set) (NODC Accession 0098574)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This Atlas, Climatic Atlas of the Sea of Azov 2008 on CD-ROM, is an update to Volume 10, Climatic Atlas of the Sea of Azov 2006 on CD-ROM (NODC Accession 0098572),...

  10. Hydrothermal synthesis of CdWO nanorods and their ...

    African Journals Online (AJOL)

    NICO

    CdWO4 has a high refractive index, a high X-ray absorption coefficient, low radiation damage, high luminescence intensity and low afterglow to .... atomic number ratio of the elements of Cd, W and O is approxi- mately 1:1:4 and is consistent ...

  11. Experimental study on gamma irradiation effects of floating gate ROMs The ROM is stated for Read-only Memory

    CERN Document Server

    He Chao Hui; Chen Xiao Hua; Wang Yan Ping; Peng Hong Lun

    2002-01-01

    Experimental results of gamma irradiation effects are given for Floating gate ROMs. There is an accumulated dose threshold. Errors occur when accumulated dose is above the threshold, no error occurs when below the threshold. The errors go up with the increase of the accumulated dose. Errors occur in devices that are measured during irradiation and irradiated in power on, moreover, new data cannot be written in these devices with programmer. However, under more accumulated dose, there is no error in devices in power off mode and new data can be written in these devices with programmer

  12. The CD4+/CD8+ Ratio in Pulmonary Tuberculosis: Systematic and Meta-Analysis Article.

    Science.gov (United States)

    Yin, Yongmei; Qin, Jie; Dai, Yaping; Zeng, Fanwei; Pei, Hao; Wang, Jun

    2015-02-01

    The ratio of CD4+/CD8+ has been used as a clinically index to evaluate patients' immunity. Numerous researchers have studied CD4+/CD8+ ratio in pulmonary tuberculosis (PTB) patients. However, the change of CD4+/CD8+ ratio remains controversial. We present a meta-analysis of 15 case-control studies to identify the change of CD4+/CD8+ ratio in PTB patients. We assessed heterogeneity of effect estimates within each group using I(2) test. Subgroup analysis was performed to explore the potential source of heterogeneity. To investigate further the potential publication bias, we visually examined the funnel plots. For robustness of results, we performed sensitivity analysis by removing studies. Data entry and analyses were carried out with RevMan 5.2 (The Nordic Cochrane Centre). Twelve peripheral blood studies were categorized into two subgroups. Eight studies presented a significant decrease of CD4+/CD8+ ratio in PTB cases compared to healthy subjects (SMD: -0.45; 95% CI -0.65--0.25; I(2) = 7%). Other four studies researched on the newly diagnosed patients presented a more seriously and significantly decrease (SMD: -2.17; 95% CI -2.61--1.74; I(2) = 37%). The pooled analysis of bronchoalveolar lavage fluid (BALF) studies showed a significant increase of CD4+/CD8+ ratio using Flow Cytometry (FCM) (SMD: 4.75; 95% CI 3.44-6.05; I(2) =0%). The present meta-analysis indicated that there was a synthetic evidence for the reduced CD4+/CD8+ ratio in peripheral blood of PTB patients, especially newly diagnosed cases. However, the CD4+/CD8+ ratio in BALF was increased using method of FCM.

  13. Analisis Portofolio Optimal Saham Syariah Menggunakan Multi Index Models (Periode: 04 Januari 2010 – 1 Juli 2013

    Directory of Open Access Journals (Sweden)

    Mulat Arja’i

    2013-10-01

    Full Text Available The portfolio is a combination or aggregation of two or more individual stock and concern for investors is to form the optimum portfolio and one of the ways that can be used are Multi-Index Models (MIM. This Model is a development of the Single Index Models (SIM, if on a SIM only consider one factor that affects the value of the stock, then return at MIM considers more than one factor. This study discusses the optimal portfolio analysis using Multi-Index Models with a case study on the stock of the Sharia Jakarta Islamic Index (JII period 4 January 2010 – 1 July 2013 by using composite stock price index (IHSG, index Dow Jones Industrial Average (DJIA and index the Hang Seng Index as a factor in MIM. The results of this research were obtained that the optimum portfolio is a portfolio that was created based on the stocks that had the highest positive return value, i.e. UNVR 41,40%, SMGR 40.66%, KLBF 11.01, and LPKR 6,93% with a value of expected return portfolio amounted to 2.55% and risk of a portfolio of 0,29%.

  14. [Cost-effectiveness in Dutch mental health care: future because of ROM?

    NARCIS (Netherlands)

    Agthoven, M. van; Kolk, A. van der; Knegtering, H.; Delespaul, P.A.; Arends, J.; Jeurissen, P.P.T.; Krabbe, P.F.M.; Huijsman, R.; Luijk, R.; Beurs, E. de; Hakkaart-van Roijen, L.; Bruggeman, R.

    2015-01-01

    BACKGROUND: The document reporting Dutch mental health care negotiations for 2014 - 2017 calls for a cost decrease based on cost-effectiveness. Thanks to rom, the Dutch mental health care seems well prepared for cost-effectiveness research.
    AIM: Evaluate how valid cost-effectiveness research

  15. Use of Multimedia tools for Training in Radiation Protection for Interventional Radiology

    International Nuclear Information System (INIS)

    Guibelalde, E.; Vano, E.

    2003-01-01

    The European Commission has published and distributed cost free in the main European languages and interactive CD-ROM for Radiation Protection Training in Interventional Radiology (MARTIR project-Radiation Protection Series N. 119-EC 2002). The CD-ROM allows: a) To select different levels of training; b) To follow a training programme as a regular course (step by step) or looking only for the topics of interest; c) To do some auto evaluation multiple choice questions at the end of the different sections or topics; d) To perform a final examination at the end of the course and to have a certification with the total time dedicated to the training programme and the obtained score in final examination. During 2001 and 2002 the MARTIR material has been distributed for evaluation purpose to different experts and it has been used in different pilot courses. In this paper the experience of using this interactive CD-ROM is discussed. The University Complutense of Madrid offers an optional specific training on Radiation Protection for the students of Medicine during their clinical period (4th to 6th year). About 100 hundred students are enrolled per year, 10% of these students follow the MARTIR CD at home as a pilot course. All of them used the CD at Least during 40 hours, completed the low level step-by-step course and pass the exam (score over 75% for 60 multiple choice questions. 87% of the students after finishing the course stated that this education methodology was very suitable for them. (Author)

  16. An index with improved diagnostic accuracy for the diagnosis of Crohn's disease derived from the Lennard-Jones criteria.

    Science.gov (United States)

    Reinisch, S; Schweiger, K; Pablik, E; Collet-Fenetrier, B; Peyrin-Biroulet, L; Alfaro, I; Panés, J; Moayyedi, P; Reinisch, W

    2016-09-01

    The Lennard-Jones criteria are considered the gold standard for diagnosing Crohn's disease (CD) and include the items granuloma, macroscopic discontinuity, transmural inflammation, fibrosis, lymphoid aggregates and discontinuous inflammation on histology. The criteria have never been subjected to a formal validation process. To develop a validated and improved diagnostic index based on the items of Lennard-Jones criteria. Included were 328 adult patients with long-standing CD (median disease duration 10 years) from three centres and classified as 'established', 'probable' or 'non-CD' by Lennard-Jones criteria at time of diagnosis. Controls were patients with ulcerative colitis (n = 170). The performance of each of the six diagnostic items of Lennard-Jones criteria was modelled by logistic regression and a new index based on stepwise backward selection and cut-offs was developed. The diagnostic value of the new index was analysed by comparing sensitivity, specificity and accuracy vs. Lennard-Jones criteria. By Lennard-Jones criteria 49% (n = 162) of CD patients would have been diagnosed as 'non-CD' at time of diagnosis (sensitivity/specificity/accuracy, 'established' CD: 0.34/0.99/0.67; 'probable' CD: 0.51/0.95/0.73). A new index was derived from granuloma, fibrosis, transmural inflammation and macroscopic discontinuity, but excluded lymphoid aggregates and discontinuous inflammation on histology. Our index provided improved diagnostic accuracy for 'established' and 'probable' CD (sensitivity/specificity/accuracy, 'established' CD: 0.45/1/0.72; 'probable' CD: 0.8/0.85/0.82), including the subgroup isolated colonic CD ('probable' CD, new index: 0.73/0.85/0.79; Lennard-Jones criteria: 0.43/0.95/0.69). We developed an index based on items of Lennard-Jones criteria providing improved diagnostic accuracy for the differential diagnosis between CD and UC. © 2016 John Wiley & Sons Ltd.

  17. Multimedia Materials for Language and Literacy Learning.

    Science.gov (United States)

    Hallett, Terry L.

    1999-01-01

    Introduces educators to inexpensive, commercially-available CD-ROM software that combines speech, text, graphics, sound, video, animation, and special effects that may be incorporated into classroom activities for both normally developing and language learning disabled children. Discusses three types of multimedia CD-ROM products: (1) virtual…

  18. Ambient Temperature Based Thermal Aware Energy Efficient ROM Design on FPGA

    DEFF Research Database (Denmark)

    Saini, Rishita; Bansal, Neha; Bansal, Meenakshi

    2015-01-01

    Thermal aware design is currently gaining importance in VLSI research domain. In this work, we are going to design thermal aware energy efficient ROM on Virtex-5 FPGA. Ambient Temperature, airflow, and heat sink profile play a significant role in thermal aware hardware design life cycle. Ambient...

  19. Influence of radiotherapy on CD4+ CD25high regulatory cells in peripheral blood of NPC patients

    International Nuclear Information System (INIS)

    Liu Li; Ding Qian; Song Yingqiu; Cao Rubo; Yao Junxia; Huang Shiang

    2006-01-01

    Objective: The current study was designed to investigate the changes in peripheral CD4 + CD25 high regulatory T (CD4 + CD25 high Tr) cells in patients with nasopharyngeal carcinoma (NPC) and the influence of radiotherapy on immunity function. Methods: The peripheral blood was collected from 36 patients with NPC and 30 healthy controls. By using monoclonal antibodies, the blood samples were evaluated with flow cytometry for lymphocyte subsets and Tr cells. Results: The ratio of CD4 + /CD8 + in the NPC group was not significantly less than that in the healthy controls (P>0.05), but the prevalence of the CD4 + CD25 high Tr cells was significantly higher than that of the healthy group [(2.76 ± 1.06)% versus (2.06 ± 0.98)%, P + CD25 high Tr cells was higher than before it [(4.88 ± 1.02)%, P + CD25 high Tr cells in peripheral blood of NPC patients with or without radiotherapy was significantly higher than those in healthy controls, which may be related to immunosupression and tumor progression in such patients. This finding suggests that CD4 + CD25 high Tr cells in peripheral blood of NPC patients can be a useful index for monitoring the immunity function. (authors)

  20. Investigation of shift in decay hazard (Scheffer) index values over the period 1969-2008 in the conterminous United States

    Science.gov (United States)

    Patricia K. Lebow; Charles G. Carll

    2010-01-01

    A statistical analysis was performed that identified time trends in the Scheffer Index value for 167 locations in the conterminous United States over the period 1969-2008. Year-to-year variation in Index values was found to be larger than year-to-year variation in most other weather parameters. Despite the substantial yearly variation, regression equations, with time (...

  1. An electrically reprogrammable 1024 bits MNOS ROM using MNOS-SOS e/d technology

    International Nuclear Information System (INIS)

    Mackowiak, E.; Le Goascoz, V.

    1976-01-01

    A 1024 bits fully decoded electrically writable and erasable non volatile ROM is described. Memory cells and peripheral circuits are made using P channel silicon on sapphire enhancement depletion technology [fr

  2. Cd pollution and ecological risk assessment for mining activity zone in Karst Area

    Science.gov (United States)

    Yang, B.; He, J. L.; Wen, X. M.; Tan, H.

    2017-08-01

    The monitored soil samples were collected from farmland in the area with mining activity in Karst area in Liupanshui. In this article, moss bag technology and TSP were used simultaneously for Cd transportation and deposition in the study area. Geostatistics and GIS were then used for the spatial distribution of Cd in the soil. Afterwards, Cd pollution to the soil environment and human health was studied by using the geo-accumulation index and potential ecological risk index methods. The results indicated that atmospheric deposition is the major route of Cd pollution. A moderate to strong pollution of Cd in the area and the degree of potential ecological risk was in a high level in the study area. Furthermore, Cd pollution in Liupanshui may originate from mining activity and atmospheric deposition.

  3. [Study on dynamic accumulation of index components from Bupleurum chinense in various collecting periods].

    Science.gov (United States)

    Wang, Qi-shuai; Li, Xiao-kun; Yang, Yun; Xiao, Gong-sheng; Feng, Wei-sheng

    2010-08-01

    To study the dynamic change law of volatile oil, saikosaponin a, d and alcohol-extract from Bupleurum chinense at Songxian region in Henan province, and to explore the optimal harvest period of Bupleurum chinense. With the contents of saikosaponin a and d, absorbance of volatile oil and percentage of alcohol-extract as indexes, HPLC-ELSD and ultraviolet spectrophotometry were successively used to analyze them. There are obvious differences among the contents of volatile oil, saikosaponin a, d and alcohol-extract in various collecting periods sample, the absorption of volatile oil in distillation was the highest in October, the content of saikosaponin a was the highest in September, the saikosaponin d in December and the percentage of alcohol-extract in October. The optimal harvest period of Bupleurum chinense at Songxian region in Henan is identified, which can provide scientific basis for crude drug production and processing.

  4. Existence and stability of periodic solutions of an impulsive differential equation and application to CD8 T-cell differentiation.

    Science.gov (United States)

    Girel, Simon; Crauste, Fabien

    2018-06-01

    Unequal partitioning of the molecular content at cell division has been shown to be a source of heterogeneity in a cell population. We propose to model this phenomenon with the help of a scalar, nonlinear impulsive differential equation (IDE). To study the effect of molecular partitioning at cell division on the effector/memory cell-fate decision in a CD8 T-cell lineage, we study an IDE describing the concentration of the protein Tbet in a CD8 T-cell, where impulses are associated to cell division. We discuss how the degree of asymmetry of molecular partitioning can affect the process of cell differentiation and the phenotypical heterogeneity of a cell population. We show that a moderate degree of asymmetry is necessary and sufficient to observe irreversible differentiation. We consider, in a second part, a general autonomous IDE with fixed times of impulse and a specific form of impulse function. We establish properties of the solutions of that equation, most of them obtained under the hypothesis that impulses occur periodically. In particular, we show how to investigate the existence of periodic solutions and their stability by studying the flow of an autonomous differential equation. Then we apply those properties to prove the results presented in the first part.

  5. Monitoring of high refractive index edible oils using coated long period fiber grating sensors

    Science.gov (United States)

    Coelho, Luís.; Viegas, Diana; Santos, José Luís.; de Almeida, Jose Manuel M. M.

    2015-05-01

    Monitoring the quality of high refractive index edible oils is of great importance for the human health. Uncooked edible oils in general are healthy foodstuff, olive oil in particular, however, they are frequently used for baking and cooking. High quality edible oils are made from seeds, nuts or fruits by mechanical processes. Nevertheless, once the mechanical extraction is complete, up to 15% of the oil remains in oil pomace and in the mill wastewater, which can be extracted using organic solvents, often hexane. Optical fiber sensors based on long period fiber gratings (LPFG) have very low wavelength sensitivity when the surround refractive index is higher than the refractive index of the cladding. Titanium dioxide (TiO2) coated LPFG could lead to the realization of high sensitivity chemical sensor for the food industry. In this work LPFG coated with a TiO2 thin film were successfully used for to detect small levels of hexane diluted in edible oils and for real time monitoring the thermal deterioration of edible oils. For a TiO2 coating of 30 nm a wavelength sensitivity of 1361.7 nm/RIU (or 0.97 nm / % V/V) in the 1.4610-1.4670 refractive index range was achieved, corresponding to 0 to 12 % V/V of hexane in olive oil. A sensitivity higher than 638 nm/RIU at 225 ºC was calculated, in the 1.4670-1.4735 refractive index range with a detection limit of thermal deterioration of about 1 minute.

  6. Optical studies of CdSe/PVA nanocomposite films

    Science.gov (United States)

    Kushwaha, Kamal Kumar; Ramrakhaini, Meera

    2018-05-01

    The nanocomposite films of CdSe nanocrystals in polyvinyl alcohol (PVA) matrix were synthesized by environmental friendly chemical method. These composites were characterized by X-ray diffraction which indicates the hexagonal crystalline structure of CdSe with crystal size up to a few nm. The crystal size is found to decrease by increasing PVA Concentration. The photoluminescence (PL) characteristics of these composite films with varying concentration of PVA as well as Cd2+ content have been investigated. The PL peak of CdSe was observed at 510 nm and higher intensity is observed by increasing PVA concentration without any change in position of PL peak. Due to proper passivation of surface states non-radiative transition are reduced which enhance the PL intensity. By increasing concentration of Cd2+ content in the CdSe/PVA nanocomposite films, smaller CdSe nanocrystals were obtained giving higher intensity and blue shift in the PL peak due to enhanced oscillator strength and quantum confinement effect. The PL peak in green and blue region makes these composite films promising materials for optical display devices. The Refractive index of these composites was also measured at sodium line with the help of Abee's refractometer and was found in the range of 2.20-2.45. It is seen that refractive index varies with polymer concentration. This may be useful for their potential application in anti-reflection coating, display devices and optical sensors.

  7. Purchasing an Encyclopedia: 12 Points To Consider. Fifth Edition.

    Science.gov (United States)

    American Library Association, Chicago, IL.

    This book discusses issues to consider when purchasing an encyclopedia and provides reviews of eight print encyclopedias, six CD-ROM encyclopedias, and one online encyclopedia. Each review provides an address and discusses the history, scope and treatment, and quality and currency of the encyclopedia; for CD-ROM encyclopedias, the database…

  8. Fusion energy 2002. 19th conference proceedings

    International Nuclear Information System (INIS)

    2003-01-01

    This CD-ROM contains the proceedings of the 19th International Conference on Fusion energy 2002, held in Lyon, France, on 14-19 October 2002. The CD-Rom contains HTML files for navigation via WEB brouser, the papers in PDF and Acrobat Reader 5 for Windows, Mac-OS and UNIX

  9. Pathological significance and prognostic roles of densities of CD57+ cells, CD68+ cells, and mast cells, and their ratios in clear cell renal cell carcinoma.

    Science.gov (United States)

    Nakanishi, Hiromi; Miyata, Yasuyoshi; Mochizuki, Yasushi; Yasuda, Takuji; Nakamura, Yuichiro; Araki, Kyohei; Sagara, Yuji; Matsuo, Tomohiro; Ohba, Kojiro; Sakai, Hideki

    2018-05-19

    The immune system is closely associated with malignant behavior in renal cell carcinoma (RCC). Therefore, understanding the pathological roles of immune cells in tumor stroma is essential to discuss the pathological characteristics of RCC. In this study, the clinical significance of densities of CD57+ cells, CD68+ cells, and mast cells, and their ratios were investigated in patients with clear cell RCC. The densities of CD57+, CD68+, and mast cells were evaluated by immunohistochemical techniques in 179 patients. Proliferation index (PI), apoptotic index (AI), and microvessel density (MVD) were evaluated by using anti-Ki-67, anti-cleaved caspase-3, and anti-CD31 antibodies, respectively. The density of CD57+ cell was negatively correlated with grade, pT stage, and metastasis, although densities of CD68+ cell and mast cell were positively correlated. Ratios of CD68+ cell/CD57+ cell and mast cell/CD57+ cell were significantly correlated with grade, pT stage, and metastasis. Survival analyses showed that the CD68+ cell/CD57+ cell ratio was a significant predictor for cause-specific survival by multi-variate analyses (hazard ratio=1.41, 95% confidential interval=1.03-1.93, P=.031), and was significantly correlated with PI, AI, and MVD (r=.47; P <. 001, r=-.31, P<.001, and r=.40, P<.001, respectively). In conclusion, CD57+ cell, CD68+ cell, and mast cell played important roles in malignancy in clear cell RCC. The CD68+ cell/CD57+ cell ratio was strongly correlated with pathological features and prognosis in these patients because this ratio reflected the status of cancer cell proliferation, apoptosis, and angiogenesis. Copyright © 2018. Published by Elsevier Inc.

  10. ANALISIS BEBERAPA FAKTOR YANG MEMPENGARUHI HOLDING PERIOD SAHAM BIASA PADA PERUSAHAAN GO PUBLIC YANG TERCATAT DALAM INDEX LQ45

    Directory of Open Access Journals (Sweden)

    Vinus - Maulina

    2012-05-01

    Full Text Available ABSTRACT   There are many factors influencing the decision making of investors in holding their possession on security especially common stock. Monetary crisis condition has proved to be able to influence the investors’ attitude in Jakarta Stock Market in investing their capital especially about the long/short of holding a security. This study is conducted based on the differentiation of conclusion/result of study from previous studies about decision to hold security in the long/short term. The aim of this study is to analyze variables influencing holding period of common stock on public firm listed in LQ 45 Index, that are firms generally have good performance assessed based on both market performance and firm fundamental, then analyzing the dominance influencing variable. This study is conducted in Jakarta Stock Exchange with population of stocks listed in LQ 45 index in period of 2000 – 2001 with the total of 64 firms. The Sample Taking Method is purposive sampling with the criteria that the firms at least listed twice in LQ45 index on the study period. The analysis method used to analyze independent variables: spread, market value, variance return, and dividend pay out ratio and dependent variable: holding period is two stage least squares multiple regression model,  since there is possibility that the correlation of bid-ask spread from the current period and bid-ask spread and holding period from the previous period for every stock take place simultaneously. Results of the study showed that, partially, bid-ask spread variable that constitutes the different value between the highest price provided paid by buyer with the lowest price offered by seller has significance positive correlation on holding period of common stock and there is inverse correlation/significance negative between variance return variable that reflect the risk rate from stock effected by fluctuation of stock price and holding period of common stock. While

  11. Adolescencia, relaciones románticas y actividad sexual: una revisión

    Directory of Open Access Journals (Sweden)

    Elvia Vargas

    2002-01-01

    Full Text Available Se presenta una revisión de algunas de las investigaciones más recientes sobre la adolescencia y los factores asociados a las relaciones románticas y la actividad sexual durante la adolescencia. Se parte de la premisa de que el análisis de la iniciación romántica y sexual durante la adolescencia requiere de modelos de causalidad múltiple que permitan dar cuenta, conjuntamente, de los factores que se encuentran en los contextos individual, familiar y social asociados con estos dos procesos. Se destaca el papel de los padres en el desarrollo de hijos adolescentes autónomos, capaces de manejar la influencia negativa del grupo de pares. Se hacen algunas recomendaciones a los responsables de diseñar programas de prevención y a los interesados en el estudio de la adolescencia y en el desarrollo de la disciplina

  12. Enhanced Cadmium (Cd Phytoextraction from Contaminated Soil using Cd-Resistant Bacterium

    Directory of Open Access Journals (Sweden)

    Kunchaya Setkit

    2014-01-01

    Full Text Available A cadmium (Cd-resistant bacterium, Micrococcus sp. MU1, is able to produce indole-3-acetic acid and promotes root elongation and plant growth. The potential of this bacterium on enhancement of Cd uptake and bioaccumulation of Cd in Helianthus annuus L. planted in Cd-contaminated soil was evaluated in greenhouse condition. The results showed that Micrococcus sp. MU1promoted the growth of H. annuus L. by increasing the root length, stem height, dry biomass, root to shoot ratio and also significantly increased Cd accumulation in the root and above-ground tissues of H. annuus L. compared to uninoculated control. Re-inoculation with Micrococcus sp. MU1in contaminated soil helped in promoting plant growth and Cd phytoextraction throughout the cultivation period. In addition, phytoextraction coefficient and translocation factor (TF of H. annuus L. inoculated with Micrococcus sp. MU1were higher than that of uninoculated control and TF continuously increased with time. Our results suggested that Micrococcus sp. MU1 has an ability to enhance plant growth and Cd uptake in H. annuus L. Synergistic interaction between Micrococcus sp. MU1 and H. annuus L. could be further applied for Cd phytoextraction in polluted areas.

  13. Influence of refraction index strength on the light propagation in dielectrics material with periodic refraction index

    International Nuclear Information System (INIS)

    Hidayat, Arif; Latifah, Eny; Kurniati, Diana; Wisodo, Hari

    2016-01-01

    This study investigated the influence of refraction index strength on the light propagation in refraction index-varied dielectric material. This dielectric material served as photonic lattice. The behavior of light propagation influenced by variation of refraction index in photonic lattice was investigated. Modes of the guiding light were determined numerically using squared-operator iteration method. It was found that the greater the strength of refraction index, the smaller the guiding modes.

  14. Proceedings of the CERI 2005 Oil Conference : What's next? CD-ROM ed.

    International Nuclear Information System (INIS)

    2005-01-01

    Recent developments in the international petroleum industry were discussed, including events unfolding in the world such as rising oil prices, world oil demand and booming oil markets. The changes reflect both fundamental and geopolitical issues such as OPEC's potential productive capacity. The presentations addressed whether these developments in the petroleum industry represent a structural shift in the market or if they are merely another cyclical movement. In addition to the outlook for world energy markets and prospects for oil supply and reserves, this conference included discussions about oil price differentials, markets for Canadian oil, geopolitical hotspots for exporting countries, enhanced recovery for conventional resources and an oil sands outlook. The role that non-conventional oil play will play in the current marketplace was also addressed. The conference featured 18 presentations, of which 6 have been indexed separately for inclusion in this database. tabs., figs

  15. Looking Up: Multimedia about Space and Flight.

    Science.gov (United States)

    Walter, Virginia A.

    1998-01-01

    The best CD-ROMs for young people about space and flight exploit the promise of hypermedia to create informative simulations. This article provides an annotated bibliography of CD-ROMs on astronomy and flight for K-12 students; suggests book and Internet connections; and highlights poetry for astronomers, science fiction, a biography of Charles…

  16. Nanomechanical recognition of prognostic biomarker suPAR with DVD-ROM optical technology

    DEFF Research Database (Denmark)

    Bache, Michael; Bosco, Filippo; Brøgger, Anna Line

    2013-01-01

    In this work the use of a high-throughput nanomechanical detection system based on a DVD-ROM optical drive and cantilever sensors is presented for the detection of urokinase plasminogen activator receptor inflammatory biomarker (uPAR). Several large scale studies have linked elevated levels...

  17. How indexes have changed

    International Nuclear Information System (INIS)

    Farrar, G.L.

    1993-01-01

    The accompanying table compares refinery construction and operating wages monthly for the years 1990 and 1991. The Nelson-Farrar refinery construction cost indexes are inflation indexes, while the operating indexes incorporate a productivity which shows improvement with experience and the increasing size of operations. The refinery construction wage indexes in the table show a steady advance over the 2-year period. Common labor indexes moved up faster than skilled indexes. Refinery operating wages showed a steady increase, while productivities averaged higher near the end of the period. Net result is that labor costs remained steady for the period

  18. Entrepreneurship in the World: The Analysis of the Global Entrepreneurship Index in the Period 2015-2017

    Directory of Open Access Journals (Sweden)

    Grădinaru Cătălin

    2017-01-01

    Full Text Available The last decades have witnessed the rapid spread of entrepreneurship all over the world. Consequently, the state of entrepreneurship has significantly improved. The aim of the paper is to present the evolution of the top ten countries in the world according to the Global Entrepreneurship Index in the period 2015-2017. The research methodology is based on a quantitative method. The paper shows that the top ten countries in the world according to this index in the last three years were the same in a high proportion and demonstrates the absolute domination of the United States of America and the growing presence of the European countries.

  19. [Analysis on acupuncture literature in Science Citation Index (SCI) periodicals in 2007].

    Science.gov (United States)

    Gao, Liang; Tian, Li-xin; Guo, Yi

    2009-06-01

    To grasp the international developing tendency of acupuncture research and provide some references for promoting acupuncture and moxibustion internationalization process, the articles about acupuncture in Science Citation Index (SCI) periodicals in 2007 were retrieved by adopting the retrieval tactics on line in combination with database searching. Results indicate that 257 articles about acupuncture had been retrived from the SCI Web databases. These articles were published in 125 journals respectively, most of which were Euramerican journals. Among these journals, the impact factor of the Journal of the American Medical Association (JAMA), 25. 547, is the highest one. It is shown that the impact factors of the SCI periodicals, in which acupuncture articles embodied are increased, the quality of these articles are improved obviously and the types of the articles are various in 2007, but there is obvious difference in the results of these studies due to the difference of experimental methods, the subjects of these experiments and acupuncture manipulations. Therefore, standardization of many problems arising from the researches on acupuncture is extremely imminent.

  20. Annual seminar on electronic sources of information

    International Nuclear Information System (INIS)

    Ravichandra Rao, I.K.

    2000-03-01

    With the rapid development in IT and the emergence of Internet, a multitude of information sources are now available on electronic media. They include e-journals and other electronic publications - online databases, reference documents, newspapers, magazines, etc. In addition to these online sources, there are thousands of CD-ROM databases. The CD-ROM databases and the online sources are collectively referred to as electronic sources of information. Libraries in no part of the world can afford to ignore these sources. Emergence of these new sources has resulted into a change in the traditional library functions including collection development, acquisitions, cataloguing, user instructions, etc. It is inevitable that in the next five to ten years, special libraries may have to allocate considerable amount towards subscription of e-journals and other e-publications. The papers in this seminar volume discuss several aspects related the theme of the seminar and cover e-journals, different sources available in the Net, classification of electronic sources, online public access catalogues, and different aspects of Internet. Papers relevant to INIS are indexed separately

  1. Rojas Zorrilla ante la crítica romántica

    Directory of Open Access Journals (Sweden)

    Pedraza Jiménez, Felipe B

    2007-06-01

    Full Text Available To Romantic Criticism, Rojas Zorrilla’s fame becomed obscure by the figure of his contemporary, friend and collaborator, Pedro Calderón de la Barca. This logical situation is clearly evident in the great german critics: Rojas Zorrilla is scarcely mentioned by the Schlegel brothers. To other historians he occupied a secondary place and the only exception was Johann Ludwig Tieck, who exalted his works even above Calderón masterpieces. It can be affirmed that Rojas Zorrilla reception was irregular. If we examine Musso Valiente’s library, Agustín Durán’s Discurso, and the romantic period editions, we will find some interest in his figure and that it was situated in a secondary place in relation to our great theater. It seems clear that Martínez de la Rosa and Alberto Lista were the critics who pay more attention to him. Martínez de la Rosa established an approach based in the neoclassic topics about our writer, meanwhile Alberto Lista developed a closer and original reading, specially centered in the poet’s tragic dimension and elements that, from his point of view, anticipated romantic Aesthetics. Rojas Zorrilla inclusion in romantic Literary Histories, and his edition in the «Biblioteca de Autores Españoles», prepared by Mesonero Romanos, make him enter the canon among the «six great stars» in Spanish Golden Age Theater.Para la crítica romántica, la fama de Rojas Zorrilla quedó oscurecida, de forma perfectamente lógica, por la de su coetáneo, amigo y colaborador don Pedro Calderón de la Barca. Esta situación es muy patente en los grandes críticos alemanes. Los hermanos Schlegel apenas citan a nuestro dramaturgo. Otros historiadores le conceden un lugar secundario, con la excepción de Johann Ludwig Tieck, que lo exaltó incluso por encima del autor de La vida es sueño. La recepción de su obra en España fue irregular. Del análisis de la biblioteca y escritos de Musso Valiente, del discurso de Agustín Durán, de las

  2. Pitfalls in the Assessment, Analysis, and Interpretation of Routine Outcome Monitoring (ROM) Data : Results from an Outpatient Clinic for Integrative Mental Health

    NARCIS (Netherlands)

    Hoenders, Rogier H. J.; Bos, Elisabeth H.; Bartels-Velthuis, Agna A.; Vollbehr, Nina K.; van der Ploeg, Karen; de Jonge, Peter; de Jong, Joop T. V. M.

    There is considerable debate about routine outcome monitoring (ROM) for scientific or benchmarking purposes. We discuss pitfalls associated with the assessment, analysis, and interpretation of ROM data, using data of 376 patients. 206 patients (55 %) completed one or more follow-up measurements.

  3. Provocarea Facebook pentru bibliotecile publice din România

    Directory of Open Access Journals (Sweden)

    Octavia-Luciana Madge

    2014-01-01

    Full Text Available Reţelele sociale şi-au câştigat rapid un loc în viaţa noastră şi în activitatea multor organizaţii şi instituţii publice şi private. La nivelul bibliotecilor, reţelele sociale şi-au demonstrat utilitatea şi rolul în calitate de instrumente de marketing pentru o mai bună comunicare cu utilizatorii. Bibliotecile publice din România au cunoscut în ultimul timp transformări mari în ceea ce priveşte modul de abordare a relaţiei cu utilizatorii şi îmbunătăţirea activităţii lor. Au lansat, de asemenea, o serie de noi servicii pentru a răspunde nevoilor comunităţii pe care o servesc şi pentru a atrage noi utilizatori. Implementarea şi utilizarea de noi aplicaţii precum reţelele de socializare online, mai exact Facebook, a fost una dintre aceste dezvoltări recente. Această lucrare analizează modul în care reţelele sociale sunt utilizate la nivelul bibliotecilor publice din România prin exemplul a trei biblioteci publice mari şi a modului în care aceste biblioteci îşi promovează serviciile prin intermediul reţelei Facebook.

  4. In situ identification of CD44+/CD24- cancer cells in primary human breast carcinomas.

    Directory of Open Access Journals (Sweden)

    Giuseppe Perrone

    Full Text Available Breast cancer cells with the CD44+/CD24- phenotype have been reported to be tumourigenic due to their enhanced capacity for cancer development and their self-renewal potential. The identification of human tumourigenic breast cancer cells in surgical samples has recently received increased attention due to the implications for prognosis and treatment, although limitations exist in the interpretation of these studies. To better identify the CD44+/CD24- cells in routine surgical specimens, 56 primary breast carcinoma cases were analysed by immunofluorescence and confocal microscopy, and the results were compared using flow cytometry analysis to correlate the amount and distribution of the CD44+/CD24- population with clinicopathological features. Using these methods, we showed that the breast carcinoma cells displayed four distinct sub-populations based on the expression pattern of CD44 and CD24. The CD44+/CD24- cells were found in 91% of breast tumours and constituted an average of 6.12% (range, 0.11%-21.23% of the tumour. A strong correlation was found between the percentage of CD44+/CD24- cells in primary tumours and distant metastasis development (p = 0.0001; in addition, there was an inverse significant association with ER and PGR status (p = 0.002 and p = 0.001, respectively. No relationship was evident with tumour size (T and regional lymph node (N status, differentiation grade, proliferative index or HER2 status. In a multivariate analysis, the percentage of CD44+/CD24- cancer cells was an independent factor related to metastasis development (p = 0.004. Our results indicate that confocal analysis of fluorescence-labelled breast cancer samples obtained at surgery is a reliable method to identify the CD44+/CD24- tumourigenic cell population, allowing for the stratification of breast cancer patients into two groups with substantially different relapse rates on the basis of CD44+/CD24- cell percentage.

  5. Index of nuclear data libraries available from the IAEA Nuclear Data Section

    International Nuclear Information System (INIS)

    Lemmel, H.D.; Schwerer, O.

    1997-01-01

    This document lists more than 100 nuclear data libraries together with references that give more detailed information about these libraries. The data libraries include neutron cross-sections, resonance parameters, fission-product yields, nuclear structure and decay data, gamma-rays from radionuclides, data of nuclear reactions induced by charged particles or heavy ions, photonuclear data, photoatomic interaction data, and many others, partly with related data processing computer codes. All data and documentation references are available upon request from the IAEA Nuclear Data Section, free of charge on magnetic tape, PC diskettes, CD-ROM or online through WWW, Telnet (menu driven within the Nuclear Data Information System NDIS), or through FTP file transfer. (author)

  6. Computer aided systems human engineering: A hypermedia tool

    Science.gov (United States)

    Boff, Kenneth R.; Monk, Donald L.; Cody, William J.

    1992-01-01

    The Computer Aided Systems Human Engineering (CASHE) system, Version 1.0, is a multimedia ergonomics database on CD-ROM for the Apple Macintosh II computer, being developed for use by human system designers, educators, and researchers. It will initially be available on CD-ROM and will allow users to access ergonomics data and models stored electronically as text, graphics, and audio. The CASHE CD-ROM, Version 1.0 will contain the Boff and Lincoln (1988) Engineering Data Compendium, MIL-STD-1472D and a unique, interactive simulation capability, the Perception and Performance Prototyper. Its features also include a specialized data retrieval, scaling, and analysis capability and the state of the art in information retrieval, browsing, and navigation.

  7. Assessment of Cd, Cr and Pb Pollution in Sediment and Water of Gheshlagh River, Iran, in September 2013

    Directory of Open Access Journals (Sweden)

    Farshid Majnoni

    2015-03-01

    Full Text Available Background: This study aimed to evaluate the pollution levels of surface water with heavy metals including Pb, Cd and Cr in Gheshlagh River, western Iran. Methods: Water and sediment were sampled in five monitoring stations with three replicates in time along the river. The concentration of Cr, Pb and Cd in both water and sediment samples were measured with graphite furnace atomic absorption spectrometer (Australia, Varian 220. The Geoaccumulation Index and Pollution Load Index were employed to assess the pollution level of sediments with heavy metals. Results: The mean value of Cd, Cr, Pb in sediment samples were 0.69, 17.19 and 10.69 µgg-1 per dry weight, respectively. Water samples contained Cd, Cr and Pb concentration of 1.99, 1.45 and 12.92 µgL-1, respectively. The Geoaccumulation Index and Pollution Load Index indicates that the sediments were not polluted with Pb and Cr, and unpolluted to moderately contaminated with Cd in Gheshlagh River. Conclusion: This study concludes that the Gheshlagh River is threatened by heavy metals particularly Cd and Pb.

  8. Synthesis, optical, structural, and electrical properties of single-crystalline CdS nanobelts

    Energy Technology Data Exchange (ETDEWEB)

    Alqahtani, Mohammed S. [King Saud University, Department of Physics and Astronomy, Riyadh (Saudi Arabia); Hadia, N.M.A.; Mohamed, S.H. [Sohag University, Physics Department, Faculty of Science, Sohag (Egypt)

    2017-04-15

    CdS nanobelts (NBs) were synthesized by vapor transport of CdS powders. The growth was carried out without any catalyst on quartz and Si (100) substrates. The synthesized CdS NBs were examined by transmission electron microscopy (TEM), field emission scanning electron microscopy (FE-SEM) and selected area electron diffraction (SAED), high-resolution transmission electron microscopy (HR-TEM), X-ray powder diffraction (XRD), energy dispersion analysis of X-ray (EDAX), spectrophotometer, and photoluminescence spectroscopy. CdS NBs were indexed as hexagonal wurtzite structure. The growth was via vapor-solid growth mechanism and along the [100] direction. The refractive index was evaluated in the transparent region, as suggested by Swanepoel, using the envelope method. The refractive index values and the extinction coefficient were decreased by increasing the wavelength. The calculated optical band gap was 2.50 eV. The photoluminescence (PL) spectrum of the synthesized CdS NBs exhibited a green emission peak at 510 nm and a broad red emission peak at 696 nm. The conductivity measurements were achieved, in the temperature range from 300 to 600 K, using the conventional two-probe technique. Two different slopes with different activation energies of 0.618 and 0.215 eV were obtained. The CdS NBs are likely being novel functional materials. Thus, they can be used in the manufacture of innovative optoelectronic nanodevices. (orig.)

  9. MoKS teistes koostööprojektides / John Grzinich

    Index Scriptorium Estoniae

    Grzinich, John

    2005-01-01

    13. III Genfis toimunud helikunstiüritusest "VernalFLUX / Kevadvool", millest Eestist võtsid osa MoKS'i koordinaatorid John Grzinich ja Evelyn Müürsepp, nende performance'ist "Maaheli. Unustatud unistused". Uuest organisatsioonist Claudmirror, mis on välja andnud seitse CD-ROM-i, nende seas John Grzinichi CD-ROM-i "Võrdsed ja kauged jooned"

  10. 75 FR 9380 - Cooperative Conservation Partners Initiative; Wetlands Reserve Enhancement Program

    Science.gov (United States)

    2010-03-02

    ... paper) of the written proposal and one electronic copy on CD-ROM in MS WORD or PDF. If submitting more... proposal and one electronic copy on CD-ROM in MS WORD or PDF. If submitting more than one project proposal... Mexico. Stretching 2,350 miles from its headwaters at Lake Itasca, Minnesota, to the mouth of the Gulf of...

  11. Artificial Intelligence-Explosive Ordnance Disposal Information Search, Retrieval, and Delivery System

    Science.gov (United States)

    1992-04-01

    megabytes greater than required to store the operating system and X-Windows. * CD-ROM Player. Standard CD-ROM player using ISO 9660 file format...CAVGERRO 235 .4596 . 8583 .0000 4.0000 42 CAVGFOUN 235 3.9362 .3700 .0000 4.0000 43 SlIT 235 172.3106 207.4205 .0000 1039.0000 44 S2T 235 122.0638

  12. Nonlinear optical behaviour of absorbing CdSxSe1-x interference filters

    International Nuclear Information System (INIS)

    Ferencz, K.; Szipoecs, R.

    1988-01-01

    First experimental results of nonlinear, thin film interference filter wedges with mixed CdS x Se 1-x as spacer material at the 633 nm wavelength of He-Ne laser are reported. Optical bistability is observed with less than 7.5 mW of optical power in single-cavity structures. The change in refractive index is found to be positive which is in accordance with the thermal mechanism of nonlinearity. Producing a double-cavity structure a device is obtained which works as an optical astable multivibrator having periodical change of transmission as the function of time. (author)

  13. Introduction and application of non-stationary standardized precipitation index considering probability distribution function and return period

    Science.gov (United States)

    Park, Junehyeong; Sung, Jang Hyun; Lim, Yoon-Jin; Kang, Hyun-Suk

    2018-05-01

    The widely used meteorological drought index, the Standardized Precipitation Index (SPI), basically assumes stationarity, but recent changes in the climate have led to a need to review this hypothesis. In this study, a new non-stationary SPI that considers not only the modified probability distribution parameter but also the return period under the non-stationary process was proposed. The results were evaluated for two severe drought cases during the last 10 years in South Korea. As a result, SPIs considered that the non-stationary hypothesis underestimated the drought severity than the stationary SPI despite that these past two droughts were recognized as significantly severe droughts. It may be caused by that the variances of summer and autumn precipitation become larger over time then it can make the probability distribution wider than before. This implies that drought expressions by statistical index such as SPI can be distorted by stationary assumption and cautious approach is needed when deciding drought level considering climate changes.

  14. High-intensity preoperative training improves physical and functional recovery in the early post-operative periods after total knee arthroplasty

    DEFF Research Database (Denmark)

    Calatayud, Joaquin; Casaña, Jose; Ezzatvar, Yasmin

    2017-01-01

    the preoperative period reduces pain and improves lower limb muscle strength, ROM and functional task performance before surgery, resulting in a reduced length of stay at the hospital and a faster physical and functional recovery after TKA. The present training programme can be used by specialists to speed up......-four subjects (7 men, 37 women) scheduled for unilateral TKA for osteoarthritis (OA) during 2014 participated in this randomized controlled trial. Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), the Physical Functioning Scale of the Short Form-36 questionnaire (SF-36), a 10-cm visual...... analogue scale (VAS), isometric knee flexion, isometric knee extension, isometric hip abduction, active knee range of motion and functional tasks (Timed Up and Go test and Stair ascent-descent test) were assessed at 8 weeks before surgery (T1), after 8 weeks of training (T2), 1 month after TKA (T3...

  15. Synthesis and structural characterization of CdS nanoparticles using nitrogen adducts of mixed diisopropylthiourea and dithiolate derivatives of Cd(II) complexes

    Science.gov (United States)

    Osuntokun, Jejenija; Ajibade, Peter A.

    2015-07-01

    [Cd(diptu)2(ced)], [Cd(diptu)2(ced)(bpy)], [Cd(diptu)2(ced)(phen)], (where diptu = diisopropyl thiourea; ced = 1-cyano-1-carboethoxylethylene-2,2‧-dithiolate; bpy = 2,2‧-bipyridine and phen = 1,10-phenanthroline) have been prepared and used as single source precursors for the preparation of hexadecylamine capped CdS nanoparticles. The precursor complexes were characterized by elemental analysis, FTIR and TGA. The structural properties of the nanoparticles were investigated using powder X-ray diffraction (XRD), transmission electron microscopy (TEM), scanning electron microscopy techniques (SEM). The optical properties of the nanoparticles were studied using UV-Visible and photoluminescence spectroscopy. The XRD analysis showed that the nanoparticles were indexed to the hexagonal phase of CdS and the TEM results showed CdS nanoparticles with average crystallite sizes of 4.00-8.80 nm.

  16. Şcoli şi biserici româneşti din Peninsula Balcanică 1864-1948. Documente de arhivă

    Directory of Open Access Journals (Sweden)

    Adina Berciu-Drăghicescu

    2006-01-01

    Full Text Available Articolul de faţă privind şcolile şi bisericile româneşti din Peninsula Balcanică în perioada 1918-1948 este realizat pe baza unor documente identificate în fonduri păstrate la Arhivele Diplomatice ale Ministerului Afacerilor Externe şi la Direcţia Arhivelor Naţioanle Istorice Centrale din Bucureşti. Au fost studiate şi selectate documente de cea mai mare semnificaţie în scopul prezentării evoluţiei situaţiei şcolilor şi bisericilor comunităţilor româneşti situate la sud de Dunăre începând cu anul 1864, când a fost înfiinţată prima şcoală în Târnova (Macedonia şi până în 1948 când statul român a abandonat acţiunea iniţiată de conducătorul Al. Ioan Cuza. Articolul prezintă această situaţie, foarte dramatică, a comunităţilor româneşti din Balcani pe baza documentelor de arhivă.

  17. Biomes and Natural Cycles. [CD-ROM].

    Science.gov (United States)

    1996

    This interactive multimedia software illustrates and explains life on planet Earth through colorful and dynamic representations. Clear explanations and animation elucidate a variety of subjects such as the organization of the ecosphere, the flux of energy, water cycles, climates, and characteristics of regions across the globe. Five animated films…

  18. Chinese Language Video Clips. [CD-ROM].

    Science.gov (United States)

    Fleming, Stephen; Hipley, David; Ning, Cynthia

    This compact disc includes video clips covering six topics for the learner of Chinese: personal information, commercial transactions, travel and leisure, health and sports, food and school. Filmed on location in Beijing, these naturalistic video clips consist mainly of unrehearsed interviews of ordinary people. The learner is lead through a series…

  19. Lineage determination of CD7+ CD5- CD2- and CD7+ CD5+ CD2- lymphoblasts: studies on phenotype, genotype, and gene expression of myeloperoxidase, CD3 epsilon, and CD3 delta.

    Science.gov (United States)

    Yoneda, N; Tatsumi, E; Teshigawara, K; Nagata, S; Nagano, T; Kishimoto, Y; Kimura, T; Yasunaga, K; Yamaguchi, N

    1994-04-01

    The gene expression of myeloperoxidase (MPO), CD3 epsilon, and CD3 delta molecules, the gene rearrangement of T-cell receptor (TCR) delta, gamma, and beta and immunoglobulin heavy (IgH) chain, and the expression of cell-surface antigens were investigated in seven cases of CD7+ CD5- CD2- and four cases of CD7+ CD5+ CD2- acute lymphoblastic leukemia or lymphoblastic lymphoma (ALL/LBL) blasts, which were negative for cytochemical myeloperoxidase (cyMPO). More mature T-lineage blasts were also investigated in a comparative manner. In conclusion, the CD7+ CD5- CD2- blasts included four categories: undifferentiated blasts without lineage commitment, T-lineage blasts, T-/myeloid lineage blasts, and cyMPO-negative myeloblasts. The CD7+ CD5+ CD2- blasts included two categories; T-lineage and T-/myeloid lineage blasts. The 11 cases were of the germ-line gene (G) for TCR beta and IgH. Four cases were G for TCR delta and TCR gamma. The others were of the monoclonally rearranged gene (R) for TCR delta and G for TCR gamma or R for both TCR delta and TCR gamma. The expression or in vitro induction of CD13 and/or CD33 antigens correlated with the immaturity of these neoplastic T cells, since it was observed in all 11 CD7+ CD5- CD2- and CD7+ CD5+ CD2-, and some CD7+ CD5+ CD2+ (CD3- CD4- CD8-) cases, but not in CD3 +/- CD4+ CD8+ or CD3+ CD4+ CD8- cases. CD3 epsilon mRNA, but not CD3 delta mRNA, was detected in two CD7+ CD5- CD2- cases, while mRNA of neither of the two CD3 molecules was detected in the other tested CD7+ CD5- CD2- cases. In contrast, mRNA of both CD3 epsilon and CD3 delta were detected in all CD7+ CD5+ CD2- cases, indicating that CD7+ CD5- CD2- blasts at least belong to T-lineage. The blasts of two CD7+ CD5- CD2- cases with entire germ-line genes and without mRNA of the three molecules (MPO, CD3 epsilon, and CD3 delta) were regarded as being at an undifferentiated stage prior to their commitment to either T- or myeloid-lineage. The co-expression of the genes of MPO

  20. Acceptability and preliminary feasibility of an internet/CD-ROM-based education and decision program for early-stage prostate cancer patients: randomized pilot study.

    Science.gov (United States)

    Diefenbach, Michael A; Mohamed, Nihal E; Butz, Brian P; Bar-Chama, Natan; Stock, Richard; Cesaretti, Jamie; Hassan, Waleed; Samadi, David; Hall, Simon J

    2012-01-13

    Prostate cancer is the most common cancer affecting men in the United States. Management options for localized disease exist, yet an evidence-based criterion standard for treatment still has to emerge. Although 5-year survival rates approach 98%, all treatment options carry the possibility for significant side effects, such as erectile dysfunction and urinary incontinence. It is therefore recommended that patients be actively involved in the treatment decision process. We have developed an Internet/CD-ROM-based multimedia Prostate Interactive Educational System (PIES) to enhance patients' treatment decision making. PIES virtually mirrors a health center to provide patients with information about prostate cancer and its treatment through an intuitive interface, using videos, animations, graphics, and texts. (1) To examine the acceptability and feasibility of the PIES intervention and to report preliminary outcomes of the program in a pilot trial among patients with a new prostate cancer diagnosis, and (2) to explore the potential impact of tailoring PIES treatment information to participants' information-seeking styles on study outcomes. Participants (n = 72) were patients with newly diagnosed localized prostate cancer who had not made a treatment decision. Patients were randomly assigned to 3 experimental conditions: (1) control condition (providing information through standard National Cancer Institute brochures; 26%), and PIES (2) with tailoring (43%) and (3) without tailoring to a patient's information-seeking style (31%). Questionnaires were administrated before (t1) and immediately after the intervention (t2). Measurements include evaluation and acceptability of the PIES intervention, monitoring/blunting information-seeking style, psychological distress, and decision-related variables (eg, decisional confidence, feeling informed about prostate cancer and treatment, and treatment preference). The PIES program was well accepted by patients and did not interfere

  1. Increased CD19+CD24+CD27+ B regulatory cells are associated with insulin resistance in patients with type I Hashimoto's thyroiditis.

    Science.gov (United States)

    Yang, Min; Du, Changji; Wang, Yinping; Liu, Jun

    2017-06-01

    Hashimoto's thyroiditis (HT) is characterized by dysregulated immune responses and is commonly associated with insulin resistance. However, the mechanism of insulin resistance in HT remains to be fully elucidated. The aim of the present study was to investigate the correlation between the percentage of B regulatory lymphocytes (Bregs) and insulin resistance in patients with HT but with normal thyroid function (type I). A total of 59 patients with type I HT and 38 healthy volunteers were enrolled in the study. An oral glucose tolerance test was performed to measure insulin secretion and assess β‑cell functions. Flow cytometry was performed to examine the percentages of lymphocyte populations. The patients with HT exhibited normal fasting and postprandial glucose and fasting insulin secretion, but increased secretion of early‑phase and total insulin. The patients with HT also had insufficient β‑cell compensation for insulin resistance, indicated by a reduced disposition index, in the fasting state. An elevation in the percentage of CD19+CD24+CD27+ Bregs was also observed, which correlated positively with insulin secretion and insulin resistance in the fasting state. The patients with type I HT had postprandial insulin resistance and insufficient β‑cell compensation for fasting insulin resistance. Therefore, the increase in CD19+CD24+CD27+ Bregs was closely associated with fasting insulin secretion. These results provide novel insight into the mechanism of insulin resistance in HT.

  2. CARA MUDAH MENYIAPKAN MATERI PEMBELAJARAN BERBASIS WEB DAN CD UNTUK BAHASA INDONESIA

    Directory of Open Access Journals (Sweden)

    Yusring Sanusi Baso

    2015-04-01

    Full Text Available Revolution of Information and Communication Technology (ICT has changed the various areas of human life, including the revolution in education. Revolution of education occurs since people migrate their way of learning from conventional to digital learning, face-to-face at a certain time and place into a meeting from anywhere and anytime. In the past we used paper, now we already headed to paperless era. Several years ago, teachers and lecturers is the source of knowledge, it is the source of knowledge can be through a variety of media, such as CD-ROMs and the Internet. The way we learn is change to distant learning with free study hour. Then, it results the term e-learning, knowledge server and knowledge based society. This article discusses how to prepare simple e-learning material (web and cd-based about Bahasa Indonesian. The program that employs to elaborate and modify the material is Hot Potatoes which is published by the University of Victoria and the Half-Baked Software. The material of Bahasa Indonesian use in this program is a set of questions on National Examination for Selection Admissions (SPMB. These questions will create an interactive multimedia material, especially web-based and CD-based material. Modules that are discussed in this article including input of data (questions, answers, etc., output configuration (modification of the display and apperance, as well as techniques to publish on the website. In addition, it will also discuss how to keep the material in the web and cd. The final result (output or material output from this program is the material that can be used as in learning Bahasa Indonesian, especially for self training and test. The Output will be in the form of website and CDs. Keywords: e-learning, Hot Potatoes, web and cd.

  3. Galvenais varonis Dž.K.Roulingas romānu sērijā "Harijs Poters"

    OpenAIRE

    Kalsone, Ineta

    2012-01-01

    Dotā bakalaura darba temats ir "Galvenais varonis Dž.K. Roulingas romānu sērijā "Harijs Poters". Pirmajā nodaļā es analizēju sērijas popularitāti, publicēšanas datus un apbalvojumus, ko saņēmusi Dž.K. Roulinga. Otrajā nodaļā tiek analizēti dažādi raksturojuma veidi. Sīkāk tiek pētīta galvenā varoņa un citu nozīmīgāko tēlu loma. Meklējuma literatūras elementi,kas dod pamatu galvenā varoņa izaugsmei, tika analizēti detalizēti. Trešajā nodaļā tiek analizēta galvenā varoņa izaugsme šajā romānu sē...

  4. Fine mapping of Best`s macular dystrophy localises the gene in close proximity to, but distinct from, the D115480/ROM1

    Energy Technology Data Exchange (ETDEWEB)

    Graff, C.; Ahlbom, B.E.; Anneren, G. [University Hospital, Uppsala (Sweden)] [and others

    1994-09-01

    Best`s macular dystrophy (BMD) is an autosomal dominant disease characterized by accumulation of lipofuscin beneath the pigment epithelium of the macula, leading to early-onset impairment of central vision. The gene has previously been mapped to 11q13. Based on DNA from 191 people from a large 12-generation family, the gene now has been mapped to a 1.5 cM interval between the markers Fc{epsilon}RI and D11S480/ROM1. By disequilibrium analysis the gene was estimated to be 0.321 cM centromeric to the marker D11S480. Since this on average corresponds to 300 kb, the gene may be at a distance contained in YAC molecules. To physically characterize this region, YAC clones positive for markers flanking BMD have been identified. Sequence analysis of the candidate gene ROM1 did not reveal any mutation. However, one recombination between intragenic ROM1 polymorphisms and BMD was detected, which make it highly unlikely that mutations in ROM1 are causing BMD.

  5. Hesperidin Inhibits Inflammatory Response Induced by Aeromonas hydrophila Infection and Alters CD4+/CD8+ T Cell Ratio

    Directory of Open Access Journals (Sweden)

    Abdelaziz S. A. Abuelsaad

    2014-01-01

    Full Text Available Background. Aeromonas hydrophila is an opportunistic bacterial pathogen that is associated with a number of human diseases. Hesperidin (HES has been reported to exert antioxidant and anti-inflammatory activities. Objectives. The aim of this study was to investigate the potential effect of HES treatment on inflammatory response induced by A. hydrophila infection in murine. Methods. A. hydrophila-infected mice were treated with HES at 250 mg/kg b.wt./week for 4 consecutive weeks. Phagocytosis, reactive oxygen species production, CD4+/CD8+ T cell ratio, and CD14 expression on intestinal infiltrating monocytes were evaluated. The expression of E-selectin and intercellular adhesion molecule 1 on stimulated HUVECs and RAW macrophage was evaluated. Results. Percentage of CD4+ T cells in the intestinal tissues of infected treated mice was highly significantly increased; however, phagocytic index, ROS production, CD8+ T cells percentage, and CD14 expression on monocytes were significantly reduced. On the other hand, HES significantly inhibited A-LPS- and A-ECP-induced E-selectin and ICAM-1 expression on HUVECs and ICAM-1 expression on RAW macrophage. Conclusion. Present data indicated that HES has a potential role in the suppression of inflammatory response induced by A. hydrophila toxins through downmodulation of ROS production and CD14 and adhesion molecules expression, as well as increase of CD4+/CD8+ cell ratio.

  6. COPPER RESISTANT STRAIN CANDIDA TROPICALIS RomCu5 INTERACTION WITH SOLUBLE AND INSOLUBLE COPPER COMPOUNDS

    Directory of Open Access Journals (Sweden)

    Ie. P. Prekrasna

    2015-10-01

    Full Text Available The focus of the study was interaction of Candida tropicalis RomCu5 isolated from highland Ecuador ecosystem with soluble and insoluble copper compounds. Strain C. tropicalis RomCu5 was cultured in a liquid medium of Hiss in the presence of soluble (copper citrate and CuCl2 and insoluble (CuO and CuCO3 copper compounds. The biomass growth was determined by change in optical density of culture liquid, composition of the gas phase was measured on gas chromatograph, redox potential and pH of the culture fluid was defined potentiometrically. The concentration of soluble copper compounds was determined colorimetrically. Maximal permissible concentration of Cu2+ for C. tropicalis RomCu5 was 30 000 ppm of Cu2+ in form of copper citrate and 500 ppm of Cu2+ in form of CuCl2. C. tropicalis was metabolically active at super high concentrations of Cu2+, despite the inhibitory effect of Cu2+. C. tropicalis immobilized Cu2+ in the form of copper citrate and CuCl2 by it accumulation in the biomass. Due to medium acidification C. tropicalis dissolved CuO and CuCO3. High resistance of C. tropicalis to Cu2+ and ability to interact with soluble and insoluble copper compounds makes it biotechnologically perspective.

  7. Bioelectric and Morphological Response of Liquid-Covered Human Airway Epithelial Calu-3 Cell Monolayer to Periodic Deposition of Colloidal 3-Mercaptopropionic-Acid Coated CdSe-CdS/ZnS Core-Multishell Quantum Dots.

    Directory of Open Access Journals (Sweden)

    Aizat Turdalieva

    Full Text Available Lung epithelial cells are extensively exposed to nanoparticles present in the modern urban environment. Nanoparticles, including colloidal quantum dots (QDs, are also considered to be potentially useful carriers for the delivery of drugs into the body. It is therefore important to understand the ways of distribution and the effects of the various types of nanoparticles in the lung epithelium. We use a model system of liquid-covered human airway epithelial Calu-3 cell cultures to study the immediate and long-term effects of repeated deposition of colloidal 3-mercaptopropionic-acid coated CdSe-CdS/ZnS core-multishell QDs on the lung epithelial cell surface. By live confocal microscope imaging and by QD fluorescence measurements we show that the QD permeation through the mature epithelial monolayers is very limited. At the time of QD deposition, the transepithelial electrical resistance (TEER of the epithelial monolayers transiently decreased, with the decrement being proportional to the QD dose. Repeated QD deposition, once every six days for two months, lead to accumulation of only small amounts of the QDs in the cell monolayer. However, it did not induce any noticeable changes in the long-term TEER and the molecular morphology of the cells. The colloidal 3-mercaptopropionic-acid coated CdSe-CdS/ZnS core-multishell QDs could therefore be potentially used for the delivery of drugs intended for the surface of the lung epithelia during limited treatment periods.

  8. Nutritional status, quality of life and CD4 cell count of adults living ...

    African Journals Online (AJOL)

    Keywords: CD4 cell count; Quality of Life; adults; nutritional status; nutritional intake. Nutritional status .... used to calculate the Body Mass Index (BMI). BMI was ... fat consumption as a percentage of the total food energy intake, and component ..... except when the CD4 counts fall very low.5,27 The CD4 cell count may offer a ...

  9. Proceedings of the CERI 2004 Oil Conference : Insecurity of supply? CD-ROM ed.

    International Nuclear Information System (INIS)

    2004-01-01

    The 21 presentations at this conference reflected recent developments in the international petroleum industry with particular focus on the outlook of world energy markets and prospects for oil supply and reserves. Topics of discussion included an outlook for world oil prices, geopolitical hotspots for oil exporting countries, and geopolitical warm spots for the former Soviet Union. The conference also featured a debate on oil supply, prices and markets for Canadian oil. The significant potential of the Western Canadian oil sands reserves was also discussed with reference to oil sands supply outlook and development issues. Several presentations reviewed environmental issues such as climate change and the responsible use of water. The conference also provided an opportunity for participants to discuss the role that non-conventional oil play will play in the current marketplace. Thirteen papers were indexed separately for inclusion in the database. tabs., figs

  10. Spectrophotometry (by Barbara Sawrey and Gabriele Wienhausen)

    Science.gov (United States)

    Pringle, David L.

    1998-08-01

    Science Media: San Diego, 1997. 1-10 copies, 99 each; 11-20 copies, 69 each; 21+ copies, $49 each. (Note: CD operates with both Mac and PC.) Spectrophotometry is an interactive CD-ROM which introduces the basics of UV-visible spectrophotometry with some mention of infrared and other forms of spectrophotometry. A Macintosh System 7.5 or higher, CPU 68040 or Power PC processor, 6 megabytes of free RAM, 2.6 megabytes of free disk space, and 4X CD-ROM or faster are required.

  11. Effect of Three Calmodulin Antagonists on Subpopulations of CD44 ...

    African Journals Online (AJOL)

    Tropical Journal of Pharmaceutical Research is indexed by Science Citation Index (SciSearch), Scopus,. International Pharmaceutical ... cancer stem cells. It is not known, however, whether targeting CD44 can alter the fate of cancer stem cells themselves. In this study, the effect of the calmodulin antagonists (N-(10-.

  12. A macrophage activation switch (MAcS)-index for assessment of monocyte/macrophage activation

    DEFF Research Database (Denmark)

    Maniecki, Maciej Bogdan; Lauridsen, Mette; Knudsen, Troels Bygum

    2008-01-01

    , simplified by the M1-M2 dichotomy of classically activated (M1), pro-inflammatory cells and alternatively activated (M2), anti-inflammatory cells. Macrophages, however, display a large degree of flexibility and are able to switch between activation states (1). The hemoglobin scavenger receptor CD163...... is expressed exclusively on monocytes and macrophages, and its expression is strongly induced by anti-inflammatory stimuli like IL10 and glucocorticoid, making CD163 an ideal M2 macrophage marker (2). Furthermore a soluble variant of CD163 (sCD163) is shed from the cell surface to plasma by protease mediated.......058-5139) (panti-inflammatory state.   CONCLUSION: We present a CD163-derived macrophage activation switch (MAcS)-index, which seems able to differentiate between (predominantly) pro-inflammatory and anti-inflammatory macrophage activation. The index needs...

  13. Proceedings of the CERI 2004 petrochemical conference : Positioning for recovery. CD-ROM ed.

    International Nuclear Information System (INIS)

    2004-01-01

    This conference provided a networking opportunity for those involved in Canada's petrochemical industry. The conditions that affect the industry were discussed along with opportunities for maintaining a competitive position in a global context. Topics of discussion included supply shortages, high costs and major shifts in international trade. It was emphasized that innovation is the key for the industry to maintain its market in a strengthening world economy. The conference featured the following 6 sessions: (1) petrochemicals in a strengthening world economy, (2) twenty-first century natural gas, the other energy crisis, (3) electricity, (4) the feedstock future, upgrading and integration opportunities, (5) adding value to resources, and (6) innovation and opportunity, prospects for new processes. Investment growth and implications for Canada were also outlined along with the challenge of product movement, including new approaches to pipeline shipments, rail transport and maritime transport. The conference featured 23 presentations, of which 9 have been indexed separately for inclusion in this database. tabs., figs

  14. Dāvida Lodža „Mazā pasaule” un „Paradīzes jaunumi” kā piedzīvojumu romāni

    OpenAIRE

    Kaušakīte, Inessa

    2007-01-01

    Maģistra darbā „Deivida Lodža „Mazā pasaule” un „Paradīzes Jaunumi” kā piedzīvojumu romāni” mērķis ir pievērst uzmanību piedzīvojuma žanra dažādām īpatnībām mūsdienu angļu romānista darbos. Darbs arī atklāj postmodernā piedzīvojumu romāna varoņa rakstura īpatnības. Pirmā nodaļa izceļ klasiskā 16. gadsimta spāņu literatūras piedzīvojumu romāna svarīgākās īpatnības. Šī nodaļa pēta apstākļus, kas palīdzējuši žanra attīstībai Anglijā. Otrā nodaļa pievērš uzmanību Deivida Lodža liktenim, kas kā...

  15. [Expression and clinical significance of CD147 in parathyroid carcinoma].

    Science.gov (United States)

    Du, X M; Wang, L L; Chang, H; Meng, W; Zhang, J Y; Shen, B

    2016-06-08

    To study the expression and clinical significance of CD147 in the patients of parathyroid carcinoma. Fourteen cases of parathyroid carcinoma encountered during the period from 2012 to 2015 were enrolled. Thirty three cases of parathyroid adenoma encountered during the same period were enrolled. The expression of CD147 in parathyroid carcinoma and parathyroid adenoma was studied by means of immunohistochemistry (EnVision method). CD147 positive color was brown and yellow, and positive position was located mainly in the cytomembrane, and a small amount of cytoplasm was appeared. Among 14 cases of parathyroid carcinoma, 11 cases of CD147 positive score was 3+ , 3 cases of CD147 positive score was 2+ ; Among 33 cases of parathyroid adenoma , 8 cases of CD147 positive score was 2+ , 15 cases of it was 1+ , 10 cases of it was negative. CD147 was highly expressed in parathyroid carcinoma tissues, and the expression of CD147 was significantly different from the expression of parathyroid adenoma(PCD147 immunohistochemical staining can help to diagnose parathyroid carcinoma.

  16. Diagnostic Performance of Bronchoalveolar Lavage Fluid CD4/CD8 Ratio for Sarcoidosis: A Meta-analysis.

    Science.gov (United States)

    Shen, Yongchun; Pang, Caishuang; Wu, Yanqiu; Li, Diandian; Wan, Chun; Liao, Zenglin; Yang, Ting; Chen, Lei; Wen, Fuqiang

    2016-06-01

    The usefulness of bronchoalveolar lavage fluid (BALF) CD4/CD8 ratio for diagnosing sarcoidosis has been reported in many studies with variable results. Therefore, we performed a meta-analysis to estimate the overall diagnostic accuracy of BALF CD4/CD8 ratio based on the bulk of published evidence. Studies published prior to June 2015 and indexed in PubMed, OVID, Web of Science, Scopus and other databases were evaluated for inclusion. Data on sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), and diagnostic odds ratio (DOR) were pooled from included studies. Summary receiver operating characteristic (SROC) curves were used to summarize overall test performance. Deeks's funnel plot was used to detect publication bias. Sixteen publications with 1885 subjects met our inclusion criteria and were included in this meta-analysis. Summary estimates of the diagnostic performance of the BALF CD4/CD8 ratio were as follows: sensitivity, 0.70 (95%CI 0.64-0.75); specificity, 0.83 (95%CI 0.78-0.86); PLR, 4.04 (95%CI 3.13-5.20); NLR, 0.36 (95%CI 0.30-0.44); and DOR, 11.17 (95%CI 7.31-17.07). The area under the SROC curve was 0.84 (95%CI 0.81-0.87). There was no evidence of publication bias. Measuring the BALF CD4/CD8 ratio may assist in the diagnosis of sarcoidosis when interpreted in parallel with other diagnostic factors. Copyright © 2016 The Authors. Published by Elsevier B.V. All rights reserved.

  17. EFFECT OF LIPOSOMAL CLODRONATE-DEPENDENT DEPLETION OF PROFESSIONAL ANTIGEN PRESENTING CELLS ON NUMBERS AND PHENOTYPE OF CANINE CD4+CD25+FOXP3+ REGULATORY T CELLS

    Science.gov (United States)

    Weaver, Kriston F.; Stokes, John V.; Gunnoe, Sagen A.; Follows, Joyce S.; Shafer, Lydia; Ammari, Mais G.; Archer, Todd M.; Thomason, John M.; Mackin, Andrew J.; Pinchuk, Lesya M.

    2015-01-01

    Regulatory T cells (Tregs) are known to control autoreactivity during and subsequent to the development of the peripheral immune system. Professional antigen presenting cells (APCs), dendritic cells (DCs) and monocytes, have an important role in inducing Tregs. For the first time, this study evaluated proportions and phenotypes of Tregs in canine peripheral blood depleted of professional APCs, utilizing liposomal clodronate (LC) and multicolor flow cytometry analysis. Our results demonstrate that LC exposure promoted short term decreases followed by significant increases in the proportions or absolute numbers of CD4+CD25+FOXP3+ Tregs in dogs. In general, the LC-dependent Treg fluctuations were similar to the changes in the levels of CD14+ monocytes in Walker hounds. However, the proportions of monocytes showed more dramatic changes compared to the proportions of Tregs that were visually unchanged after LC treatment over the study period. At the same time, absolute Treg numbers showed, similarly to the levels of CD14+ monocytes, significant compensatory gains as well as the recovery during the normalization period. We confirm the previous data that CD4+ T cells with the highest CD25 expression were highly enriched for FOXP3. Furthermore, for the first time, we report that CD4+CD25lowFOXP3+ is the major regulatory T cell subset affected by LC exposure. The increases within the lowest CD25 expressers of CD4+FOXP3+ cells together with compensatory gains in the proportion of CD14+ monocytes during compensatory and normalization periods suggest the possible direct or indirect roles of monocytes in active recruitment and generation of Tregs from naïve CD4+ T cells. PMID:25950023

  18. Future directions in nuclear data publication

    International Nuclear Information System (INIS)

    Firestone, R.B.; Chu, S.Y.F.; Ekstroem, L.P.; Nordberg, H.

    1997-01-01

    Rapid advances in computer based technologies provide enormous opportunities and great challenges to the way nuclear data is disseminated. Simple text databases and linear, command driven software are giving way to more complex, indexed databases and object-oriented, menu-driven applications. The Internet will clearly dominate dissemination of nuclear data in for foreseeable future, and CD-ROM technology (or similar high-density media) will replace hard-copy publication. The Isotopes Project has released Version 1.0 of VuENSDF, a versatile, 32-bit, C ++ , Internet enabled application for disseminating nuclear data. VuENSDF can automatically retrieve data over Internet; display decay scheme drawings, level tables, and references; and perform limited database searching of nuclear bands, transition coincidences, and reference authors. Version 2.0 of VuENSDF is being developed and will offer more complete database searches, plotting, and data entry utilities. The Isotopes Project has established a series of home pages on the WWW to provide data for various topics of nuclear physics. The group has also published a CD-ROM version of the Table of Isotopes using Adobe Acrobat software. Updated, Internet versions of the Table of Isotopes are planned. (author)

  19. [Five years of ROM in substance abuse treatment centres in the Netherlands].

    Science.gov (United States)

    Oudejans, S C C; Schippers, G M; Spits, M E; Stollenga, M; van den Brink, W

    2012-01-01

    Three substance abuse treatment centres set up a benchmarking project for routine outcome management (ROM) of structured cognitive behavioral treatments for outpatients with a substance use disorder. To present the results of five years benchmarking. All patients were included at intake and the follow-up assessment was performed by a call-center nine months later. Twice a year aggregated data were fed back to management and treatment teams. Since 2005, clinical outcome data, including substance abuse data, have been collected for more than half of all 15.786 treated patients. At follow-up, nine months after intake, 23% was abstinent, 28% reported moderate substance use and 49% reported excessive substance use. The Dutch centres for the treatment of substance abuse were successful in setting up ROM projects to monitor and compare the development and the effects of outpatient addiction treatments. The clinical results are acceptable and correspond to the results of the American project called match. It is not yet clear whether the biannual feedback of aggregated outcomes to management and treatment teams has contributed to the creation of learning organisations, but it has provided transparency and has made it possible for teams to learn from the outcomes.

  20. LOYALTY – THE NUCLEUS OF BRAND CAPITAL. CASE STUDY: ROM CHOCOLATE BAR

    Directory of Open Access Journals (Sweden)

    Brindusa Mariana Amalancei

    2013-12-01

    Full Text Available It is considered that loyalty to the brand of some primary customers is the core of the brand capital. A brand, however, may have substantial value, which is given to it by its symbol and slogans, if it is continued with the purchase of a brand after the buyers have made a comparison with the competing products that have superior characteristics. Structured on several levels, which are each a different marketing challenge, the loyalty to the brand consists of many factors, among which the most important is the user experience. The paper aims to highlight, starting from a series of articles in online media, the manner in which a traditional Romanian brand, ROM chocolate bar, continuously repositions itself, attempting to maintain and even increase the loyalty of its consumers, as well as to answer the consumer’s authenticity, accessibility, credibility and modernity needs. Even though in specialized literature there are opinions according to which traditional brands are commonly old-fashioned or dull, ROM chocolate bar shows the opposite view, being considered a successful brand which is appreciated both at national and international levels.

  1. Using multimedia to link experts' views and derive common conclusions

    DEFF Research Database (Denmark)

    Howard, Rob

    1997-01-01

    Introductory paper to an issue of Automation in Construction edited by the author with papers from several contributors to the Building IT 2005 multimedia CD-ROM on the future of IT in the construction industry......Introductory paper to an issue of Automation in Construction edited by the author with papers from several contributors to the Building IT 2005 multimedia CD-ROM on the future of IT in the construction industry...

  2. Effect of age and latent CMV infection on CD8+ CD56+ T cells (NKT-like) frequency and functionality.

    Science.gov (United States)

    Hassouneh, Fakhri; Campos, Carmen; López-Sejas, Nelson; Alonso, Corona; Tarazona, Raquel; Solana, Rafael; Pera, Alejandra

    2016-09-01

    Changes in the T cell pool caused by CMV infection have been proposed to contribute to immunosenescence, but it has been postulated that CMV can also have some beneficial effects in young individuals improving the immune response to other pathogens. T cells expressing CD56 (NKT-like cells) are cytotoxic effector cells with a significant role in the immune response against cancer. We have studied how age and latent CMV infection affect the frequency of NKT-like cells (CD8+ CD56+ T cells) and their response to Staphylococcal Enterotoxin B (SEB) in the context of CMV and ageing. NKT-like cell percentage increases with the combination of both CMV and age. The response to SEB and the polyfunctional index of NKT-like cells also increase with age in CMV-seropositive individuals. In young individuals, CMV infection induces a shift on the polyfunctional profile of CD8+ CD56- T cells not observed on the NKT-like cells response. NKT-like cells expressing CD57 are expanded in CMV-seropositive individuals and are more polyfunctional than their CD57-  counterpart. In addition CD57- NKT-like cells are more polyfunctional than CD8+ CD56- CD57- T cells. The results support that the expansion of polyfunctional NKT-cells may have a beneficial effect on the immune response against pathogens. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  3. Assessment of soil contamination by potentially toxic trace elements (PTSD) (As, Cd, Cu, Hg, Pb, Zn) in a lower plain of the Hron River according to Law no. 219/2008 Coll., by geo-accumulation index, anthropogenic factor and Tomlinson index; Zhodnotenie kontaminacie pod potencialne toxickymi stopovymi prvkami (PTSP) (As, Cd, Cu, Hg, Pb, Zn) v dolnej casti nivy Hrona podla zakona c. 219/2008 Z.z., indexu geoakumulacie, antropogenneho faktora a Tomlinsonovho indexu

    Energy Technology Data Exchange (ETDEWEB)

    Hlodak, M [Univerzita Komenskeho v Bratislave, Prirodovedecka fakulta, Ustav laboratorneho vyskumu geomaterialov, 84215 Bratislava (Slovakia)

    2012-04-25

    Soil contamination by different PTSD may have different geogenic and anthropogenic origin and occurs in all countries of the world. The aim of this paper is to evaluate the soils contamination of a lower plain of the Hron River. This paper used the results of the thesis Soil contamination of the Hron River floodplain by trace elements (As, Cd, Cu, Hg, Pb, Zn) [1]. Soil contamination was evaluated by: Act. 219/2008 Coll. on the protection and use of agricultural land, by anthropogenic factor (AF), geo-accumulation index (IgeoE) and Tomlinson index - the index of the pollution load (PLI). (author)

  4. Poverty index with time-varying consumption and income distributions

    Science.gov (United States)

    Chattopadhyay, Amit K.; Kumar, T. Krishna; Mallick, Sushanta K.

    2017-03-01

    Starting from a stochastic agent-based model to represent market exchange in a developing economy, we study time variations of the probability density function of income with simultaneous variation of the consumption deprivation (CD), where CD represents the shortfall in consumption from the saturation level of an essential commodity, cereal. Together, these two models combine income-expenditure-based market dynamics with time variations in consumption due to income. In this new unified theoretical structure, exchange of trade in assets is only allowed when the income exceeds consumption-deprivation while CD itself is endogenously obtained from a separate kinetic model. Our results reveal that the nature of time variation of the CD function leads to a downward trend in the threshold level of consumption of basic necessities, suggesting a possible dietary transition in terms of lower saturation level of food-grain consumption, possibly through an improvement in the level of living. The new poverty index, defined as CD, is amenable to approximate probabilistic prediction within a short time horizon. A major achievement of this work is the intrinsic independence of the poverty index from an exogenous poverty line, making it more objective for policy formulation as opposed to existing poverty indices in the literature.

  5. SEM REGRA NEM FREIOS - Loucura e criação na discussão romântica em torno do gênio

    Directory of Open Access Journals (Sweden)

    Yuri Cerqueira dos Anjos

    2014-12-01

    Full Text Available A relação entre genialidade e loucura, tópos bastante antigo, parece ganhar contornos peculiares no pensamento romântico. Inspirado, ultrassensível, isolado e visionário, o gênio romântico transita com certa frequência no campo semântico da loucura. Entre oráculo, profeta e louco, ele se caracteriza pela sua capacidade de transgredir o estado atual das coisas e criar um novo mundo de possibilidades e experiências. Nesse sentido, exploraremos no presente artigo alguns aspectos dessa relação entre o gênio e o louco no contexto do debate romântico francês do início do século XIX e no livro William Shakespeare, de Victor Hugo.

  6. Optical, structural and surface characterization of ultrasonically sprayed CdO:F films

    International Nuclear Information System (INIS)

    Akyuz, I.; Kose, S.; Ketenci, E.; Bilgin, V.; Atay, F.

    2011-01-01

    Research highlights: → The effect of F doping on the optical, structural and surface properties of ultrasonically sprayed CdO films has been investigated. F doping affected each of these properties. → The low cost of the production system is an advantage for potential applications of these films. CF4 film caused the transmittance values to increase which is a desired development for transparent conducting oxide industry. → Low reflectance value of CF2 film makes this sample a promising material for anti-reflection coatings. → F doping has found to be an alternative solution to increase the narrow band gap of CdO films. This is an other development of CdO:F films for optoelectronic and photovoltaic solar cell applications. → Rough samples may be an alternative in single-junction μc-Si solar cells having superstrate configuration. When we take into account the refractive index and rough surface of the samples, rough interface between a low refractive index material (CdO:F, n ∼ 1.6) and a high refractive index material (for Si n ∼ 3.7) results in reduced reflection due to gradual refractive index matching. In order to increase this effect high rms roughness (R q ) values needed. Also this will allow light trapping into Si layer and cause back and forth scattering at the interfaces increasing the optical path within the Si layer. - Abstract: In this work, we report the effect of F doping on some physical properties of CdO films. Ultrasonic spray pyrolysis technique has been used to obtain the films. Thicknesses, refractive indices and extinction coefficients of the films have been determined by spectroscopic ellipsometry technique using Cauchy-Urbach model for fitting. Transmission and reflectance spectra have been taken by UV spectrophotometer, and band gap values have been determined by optical method. X-ray diffraction patterns have been used to study the structural properties such as crystallinity level, texture coefficient, crystallite size and

  7. Proceedings of the CERI 2003 electricity conference : electricity restructuring in transition. CD-ROM ed.

    International Nuclear Information System (INIS)

    2003-01-01

    The restructuring of the electric power industry was reviewed from a North American perspective. This conference focused on how current market structures can be improved to benefit all participants. The current issues for future development of power generation and transmission were discussed. The conference was divided into seven sessions as follows: (1) market design issues, (2) Federal Energy Regulatory Commission's (FERC's) wholesale market platform, (3) does retail competition make sense, (4) the future direction of the Alberta market, (5) the status of restructured electricity markets, (6) resource mix in a greenhouse gas (GHG)-constrained world, and (7) electricity supply from oil sands cogeneration. A total of eleven papers were selected and indexed separately for inclusion in this database. refs., tabs., figs

  8. Perspective on One Decade of Laser Propulsion Research at the Air Force Research Laboratory, November 1995-2005 (DVD)

    National Research Council Canada - National Science Library

    2007-01-01

    .... PHYSICAL DESCRIPTION: 1 DVD-ROM and 1 CD-ROM; 4 3/4 in.; 395 MB. ABSTRACT: A short film and presentation on laser propulsion research at the Air Force Research Laboratory, spanning November 1995 through October 2005...

  9. Self-assembly of charged microclusters of CdSe/ZnS core/shell nanodots and nanorods into hierarchically ordered colloidal arrays

    International Nuclear Information System (INIS)

    Sukhanova, Alyona; Baranov, Alexander V; Klinov, Dmitriy; Oleinikov, Vladimir; Berwick, Kevin; Cohen, Jacques H M; Pluot, Michel; Nabiev, Igor

    2006-01-01

    A thermodynamically driven self-organization of microclusters of semiconductor nanocrystals with a narrow size distribution into periodic two-dimensional (2D) arrays is an attractive low-cost technique for the fabrication of 2D photonic crystals. We have found that CdSe/ZnS core/shell quantum dots or quantum rods, transferred in aqueous phase after capping with the bifunctional surface-active agent DL-cysteine, form on a poly-L-lysine coated surface homogeneously sized micro-particles, droplet-like spheroid clusters and hexagon-like colloidal crystals self-organized into millimetre-sized 2D hexagonal assemblies. The presence of an organic molecular layer around the micro-particles prevents immediate contact between them, forming an interstitial space which may be varied in thickness by changing the origin of the molecular layer capping nanocrystals. Due to the high refractive index of CdSe and the low refractive index of the interstitial spaces, these structures are expected to have deep gaps in their photonic band, forming hierarchically ordered 2D arrays of potentially photonic materials

  10. A multimedia package for particle technology

    International Nuclear Information System (INIS)

    Mathers, B.; Rhodes, M.; Iveson, S.

    2002-01-01

    A CD-ROM-based package is being prepared for Particle Technology education. It is based on the textbook 'Introduction to Particle Technology' by Martin Rhodes, and aims to expand on the information given in the text by making best possible use of the advantages offered by the CD-ROM format, including use of videos, animations and interactive functions. The CD-ROM will be divided into the same twelve sections as the text. Each section will have subsections of: 1) Industrial Relevance (showing a video and/or photos and explanation of how the subject matter is used in industry). 2) Experiment/Demonstration (a video where measurements can be taken by the user, or explanatory video and raw data provided. The user will be given directions on how to carry out the experiment and the necessary calculations). 3) Quiz (multiple choice format testing the knowledge gained in the previous sections). 4) Calculators (allowing the user to easily make important particle technology calculations) The CD-ROM will allow users the opportunity to observe particulate processes and operations without the necessity of participating in laboratories or site visits, and will therefore be a useful tool for distance education, for users learning on an individual basis or as an addition to institutionally based particle technology courses

  11. CD4 Counts at Entry to HIV Care in Mexico for Patients under the "Universal Antiretroviral Treatment Program for the Uninsured Population," 2007-2014.

    Science.gov (United States)

    Hernández-Romieu, Alfonso C; del Rio, Carlos; Hernández-Ávila, Juan Eugenio; Lopez-Gatell, Hugo; Izazola-Licea, José Antonio; Uribe Zúñiga, Patricia; Hernández-Ávila, Mauricio

    2016-01-01

    In Mexico, public health services have provided universal access to antiretroviral therapy (ART) since 2004. For individuals receiving HIV care in public healthcare facilities, the data are limited regarding CD4 T-lymphocyte counts (CD4e) at the time of entry into care. Relevant population-based estimates of CD4e are needed to inform strategies to maximize the impact of Mexico's national ART program, and may be applicable to other countries implementing universal HIV treatment programs. For this study, we retrospectively analyzed the CD4e of persons living with HIV and receiving care at state public health facilities from 2007 to 2014, comparing CD4e by demographic characteristics and the marginalization index of the state where treatment was provided, and assessing trends in CD4e over time. Our sample included 66,947 individuals who entered into HIV care between 2007 and 2014, of whom 79% were male. During the study period, the male-to-female ratio increased from 3.0 to 4.3, reflecting the country's HIV epidemic; the median age at entry decreased from 34 years to 32 years. Overall, 48.6% of individuals entered care with a CD4≤200 cells/μl, ranging from 42.2% in states with a very low marginalization index to 52.8% in states with a high marginalization index, and from 38.9% among individuals aged 18-29 to 56.5% among those older than 50. The adjusted geometric mean (95% confidence interval) CD4e increased among males from 135 (131,142) cells/μl in 2007 to 148 (143,155) cells/μl in 2014 (p-valuewomen, with a geometric mean of 178 (171,186) and 171 (165,183) in 2007 and 2014, respectively. There have been important gains in access to HIV care and treatment; however, late entry into care remains an important barrier in achieving optimal outcomes of ART in Mexico. The geographic, socioeconomic, and demographic differences observed reflect important inequities in timely access to HIV prevention, care, and treatment services, and highlight the need to develop

  12. CD4 Counts at Entry to HIV Care in Mexico for Patients under the "Universal Antiretroviral Treatment Program for the Uninsured Population," 2007-2014.

    Directory of Open Access Journals (Sweden)

    Alfonso C Hernández-Romieu

    Full Text Available In Mexico, public health services have provided universal access to antiretroviral therapy (ART since 2004. For individuals receiving HIV care in public healthcare facilities, the data are limited regarding CD4 T-lymphocyte counts (CD4e at the time of entry into care. Relevant population-based estimates of CD4e are needed to inform strategies to maximize the impact of Mexico's national ART program, and may be applicable to other countries implementing universal HIV treatment programs. For this study, we retrospectively analyzed the CD4e of persons living with HIV and receiving care at state public health facilities from 2007 to 2014, comparing CD4e by demographic characteristics and the marginalization index of the state where treatment was provided, and assessing trends in CD4e over time. Our sample included 66,947 individuals who entered into HIV care between 2007 and 2014, of whom 79% were male. During the study period, the male-to-female ratio increased from 3.0 to 4.3, reflecting the country's HIV epidemic; the median age at entry decreased from 34 years to 32 years. Overall, 48.6% of individuals entered care with a CD4≤200 cells/μl, ranging from 42.2% in states with a very low marginalization index to 52.8% in states with a high marginalization index, and from 38.9% among individuals aged 18-29 to 56.5% among those older than 50. The adjusted geometric mean (95% confidence interval CD4e increased among males from 135 (131,142 cells/μl in 2007 to 148 (143,155 cells/μl in 2014 (p-value<0.0001; no change was observed among women, with a geometric mean of 178 (171,186 and 171 (165,183 in 2007 and 2014, respectively. There have been important gains in access to HIV care and treatment; however, late entry into care remains an important barrier in achieving optimal outcomes of ART in Mexico. The geographic, socioeconomic, and demographic differences observed reflect important inequities in timely access to HIV prevention, care, and treatment

  13. Abordagens do amor romântico: aspectos históricos, sociais e literários

    Directory of Open Access Journals (Sweden)

    Luana Grasiela Schonarth

    2015-06-01

    Full Text Available O presente estudo vincula-se ao projeto de pesquisa Narrativas e conhecimentos: especificidades teóricas e constituição de sentido, coordenado pela Prof.ª Dra. Eunice Terezinha Piazza Gai. Considerando os caminhos cursados no desenvolvimento da pesquisa, utilizamos o tema do amor para refletir sobre os possíveis conhecimentos que o processo narrativo propicia, os aspectos históricos e sociais nos quais a temática foi abordada na literatura, assim como um resgate de informações acerca das origens do tema e personagens consolidados nos romances românticos. Nessa perspectiva, delimitamos o estudo entre os amores irrealizados, os impasses responsáveis pelos impedimentos amorosos, bem como os conflitos entre a paixão e o casamento nas narrativas românticas. Para bem fundamentar esta pesquisa, tomamos o mito considerado matriz das histórias de amor, o próprio nascimento da paixão na literatura ocidental: Tristão e Isolda. O mito apresenta a visão do amor cortês e as contradições que se manifestaram desde a segunda metade do século XII entre a regra cavalheiresca e os costumes feudais. Diante da teoria do amor, abstraída do mito do amor romântico, partimos para a literatura do século XIX, considerando a presença dos amores não correspondidos. Nesta etapa, analisamos o romance de Balzac, Eugênia Grandet, que se torna exemplo da irrealização amorosa na literatura, vivida de modo mais contundente pela personagem que intitula a obra. A escolha dessa narrativa, para a análise do amor-paixão, deve-se ao fato de que o casamento é tratado como mero interesse financeiro, desconsiderando todo e qualquer envolvimento amoroso entre o casal em questão: Eugênia e Charles. Tratamos, pois, desta pluralidade significativa, deste amplo caminho trilhado não só pela literatura, mas por todos aqueles que se deixam despertar pela eternidade e fascínio dos romances românticos.

  14. The development of a magnetic resonance imaging index for fistulising Crohn's disease

    NARCIS (Netherlands)

    Samaan, M. A.; Puylaert, C. A. J.; Levesque, B. G.; Zou, G. Y.; Stitt, L.; Taylor, S. A.; Shackelton, L. M.; Vandervoort, M. K.; Khanna, R.; Santillan, C.; Rimola, J.; Hindryckx, P.; Nio, C. Y.; Sandborn, W. J.; D'Haens, G.; Feagan, B. G.; Jairath, V.; Stoker, J.

    2017-01-01

    Magnetic resonance imaging (MRI) is the gold standard for assessment of perianal fistulising Crohn's disease (CD). The Van Assche index is the most commonly used MRI fistula index. To assess the reliability of the Van Assche index, and to modify the instrument to improve reliability and create a

  15. A Fuel-Sensitive Reduced-Order Model (ROM) for Piston Engine Scaling Analysis

    Science.gov (United States)

    2017-09-29

    of high Reynolds number nonreacting and reacting JP-8 sprays in a constant pressure flow vessel with a detailed chemistry approach . J Energy Resour...for rapid grid generation applied to in-cylinder diesel engine simulations. Society of Automotive Engineers ; 2007 Apr. SAE Technical Paper No.: 2007...ARL-TR-8172 ● Sep 2017 US Army Research Laboratory A Fuel-Sensitive Reduced-Order Model (ROM) for Piston Engine Scaling Analysis

  16. CD4 T lymphocyte counts in patients undergoing splenectomy during living donor liver transplantation.

    Science.gov (United States)

    Natsuda, Koji; Eguchi, Susumu; Takatsuki, Mistuhisa; Soyama, Akihiko; Hidaka, Masaaki; Hara, Takanobu; Kugiyama, Tota; Baimakhanov, Zhassulan; Ono, Shinichiro; Kitasato, Amane; Fujita, Fumihiko; Kanetaka, Kengo; Kuroki, Tamotsu

    2016-02-01

    The role of splenectomy in increasing the CD4-positive T lymphocyte counts (hereafter: CD4 counts) and the CD4 to CD8 ratio have not yet been fully investigated, especially in the case of HIV-positive patients undergoing liver transplantation (LT). The change in the total lymphocyte counts of 32 patients who underwent one-stage splenectomy with living donor (LD) LT with (n=13) or without rituximab (RTX, n=19) therapy were examined to validate our cohort of ABO-incompatible LDLT with RTX. Subsequently, perioperative changes in CD4 counts and the CD 4 to CD8 ratio were measured in 13 patients who underwent ABO-incompatible LDLT/RTX with splenectomy. (1) The administration of RTX did not significantly affect the total lymphocyte counts of patients after LDLT/splenectomy in any of the observation periods. (2) The CD4 counts were significantly higher at 2years after LDLT in comparison to the perioperative CD4 counts but not within the 3-month period (p=0.039). The CD4/CD8 ratio gradually decreased after LDLT/splenectomy under RTX treatment. An immediate increase in the CD4 counts therefore cannot be expected after LDLT with splenectomy. The total lymphocyte and CD4 counts were rather stable in the peritransplant period even in ABO incompatible LDLT with RTX. Copyright © 2015 Elsevier B.V. All rights reserved.

  17. A viral long terminal repeat expressed in CD4+CD8+ precursors is downregulated in mature peripheral CD4-CD8+ or CD4+CD8- T cells.

    OpenAIRE

    Paquette, Y; Doyon, L; Laperrière, A; Hanna, Z; Ball, J; Sekaly, R P; Jolicoeur, P

    1992-01-01

    The long terminal repeat from a thymotropic mouse mammary tumor virus variant, DMBA-LV, was used to drive the expression of two reporter genes, murine c-myc and human CD4, in transgenic mice. Expression was observed specifically in thymic immature cells. Expression of c-myc in these cells induced oligoclonal CD4+ CD8+ T-cell thymomas. Expression of human CD4 was restricted to thymic progenitor CD4- CD8- and CD4+ CD8+ T cells and was shut off in mature CD4+ CD8- and CD4- CD8+ T cells, known to...

  18. Volcanoes of the Wrangell Mountains and Cook Inlet region, Alaska: selected photographs

    Science.gov (United States)

    Neal, Christina A.; McGimsey, Robert G.; Diggles, Michael F.

    2001-01-01

    Alaska is home to more than 40 active volcanoes, many of which have erupted violently and repeatedly in the last 200 years. This CD-ROM contains 97 digitized color 35-mm images which represent a small fraction of thousands of photographs taken by Alaska Volcano Observatory scientists, other researchers, and private citizens. The photographs were selected to portray Alaska's volcanoes, to document recent eruptive activity, and to illustrate the range of volcanic phenomena observed in Alaska. These images are for use by the interested public, multimedia producers, desktop publishers, and the high-end printing industry. The digital images are stored in the 'images' folder and can be read across Macintosh, Windows, DOS, OS/2, SGI, and UNIX platforms with applications that can read JPG (JPEG - Joint Photographic Experts Group format) or PCD (Kodak's PhotoCD (YCC) format) files. Throughout this publication, the image numbers match among the file names, figure captions, thumbnail labels, and other references. Also included on this CD-ROM are Windows and Macintosh viewers and engines for keyword searches (Adobe Acrobat Reader with Search). At the time of this publication, Kodak's policy on the distribution of color-management files is still unresolved, and so none is included on this CD-ROM. However, using the Universal Ektachrome or Universal Kodachrome transforms found in your software will provide excellent color. In addition to PhotoCD (PCD) files, this CD-ROM contains large (14.2'x19.5') and small (4'x6') screen-resolution (72 dots per inch; dpi) images in JPEG format. These undergo downsizing and compression relative to the PhotoCD images.

  19. Regulatory function of cytomegalovirus-specific CD4+CD27-CD28- T cells

    International Nuclear Information System (INIS)

    Tovar-Salazar, Adriana; Patterson-Bartlett, Julie; Jesser, Renee; Weinberg, Adriana

    2010-01-01

    CMV infection is characterized by high of frequencies of CD27 - CD28 - T cells. Here we demonstrate that CMV-specific CD4 + CD27 - CD28 - cells are regulatory T cells (T R ). CD4 + CD27 - CD28 - cells sorted from CMV-stimulated PBMC of CMV-seropositive donors inhibited de novo CMV-specific proliferation of autologous PBMC in a dose-dependent fashion. Compared with the entire CMV-stimulated CD4 + T-cell population, higher proportions of CD4 + CD27 - CD28 - T R expressed FoxP3, TGFβ, granzyme B, perforin, GITR and PD-1, lower proportions expressed CD127 and PD1-L and similar proportions expressed CD25, CTLA4, Fas-L and GITR-L. CMV-CD4 + CD27 - CD28 - T R expanded in response to IL-2, but not to CMV antigenic restimulation. The anti-proliferative effect of CMV-CD4 + CD27 - CD28 - T R significantly decreased after granzyme B or TGFβ inhibition. The CMV-CD4 + CD27 - CD28 - T R of HIV-infected and uninfected donors had similar phenotypes and anti-proliferative potency, but HIV-infected individuals had higher proportions of CMV-CD4 + CD27 - CD28 - T R . The CMV-CD4 + CD27 - CD28 - T R may contribute to the downregulation of CMV-specific and nonspecific immune responses of CMV-infected individuals.

  20. Enerdata statistical yearbook. ''the key-data of energy worldwide''. 1999 data

    International Nuclear Information System (INIS)

    2000-01-01

    The new edition of the Enerdata statistical yearbook provides the most recent statistical data on energy (oil, gas, coal and power production) and CO 2 emissions worldwide for the 1994-1999 period of time. These data cover 52 countries and 12 geographic areas and are presented in the form of tables and graphs (production, foreign exchanges, consumptions, market shares, sectoral consumption, 1999 energy status, long-term tendencies). More data for a longer period (1970-1999) and for all countries worldwide are available on the CD-Rom version of the yearbook. (J.S.)

  1. Proceedings of the CIB World Building Congress 2004 : Building for the future. CD-ROM ed.

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    This conference provided an opportunity to exchange information on recent building and construction research. The main issues were arranged into the following sessions: building techniques; buildings and the environment; building processes; sustainable construction; performance based buildings and regulatory systems; revaluing construction; and, construction in developing countries. The presentations evaluated best practices in construction with reference to a wide range of topics, including heat, air and moisture transfer in buildings, roofing materials, energy conservation, building economics, urban sustainability and the future needs of the construction industry. The conference featured 40 presentations, of which 6 have been indexed separately for inclusion in this database. refs., tabs. ,figs.

  2. Cryosphere-hydrosphere interactions: numerical modeling using the Regional Ocean Modeling System (ROMS) at different scales

    Science.gov (United States)

    Bergamasco, A.; Budgell, W. P.; Carniel, S.; Sclavo, M.

    2005-03-01

    Conveyor belt circulation controls global climate through heat and water fluxes with atmosphere and from tropical to polar regions and vice versa. This circulation, commonly referred to as thermohaline circulation (THC), seems to have millennium time scale and nowadays--a non-glacial period--appears to be as rather stable. However, concern is raised by the buildup of CO2 and other greenhouse gases in the atmosphere (IPCC, Third assessment report: Climate Change 2001. A contribution of working group I, II and III to the Third Assessment Report of the Intergovernmental Panel on Climate Change (Cambridge Univ. Press, UK) 2001, http://www.ipcc.ch) as these may affect the THC conveyor paths. Since it is widely recognized that dense-water formation sites act as primary sources in strengthening quasi-stable THC paths (Stommel H., Tellus131961224), in order to simulate properly the consequences of such scenarios a better understanding of these oceanic processes is needed. To successfully model these processes, air-sea-ice-integrated modelling approaches are often required. Here we focus on two polar regions using the Regional Ocean Modeling System (ROMS). In the first region investigated, the North Atlantic-Arctic, where open-ocean deep convection and open-sea ice formation and dispersion under the intense air-sea interactions are the major engines, we use a new version of the coupled hydrodynamic-ice ROMS model. The second area belongs to the Antarctica region inside the Southern Ocean, where brine rejections during ice formation inside shelf seas origin dense water that, flowing along the continental slope, overflow becoming eventually abyssal waters. Results show how nowadays integrated-modelling tasks have become more and more feasible and effective; numerical simulations dealing with large computational domains or challenging different climate scenarios can be run on multi-processors platforms and on systems like LINUX clusters, made of the same hardware as PCs, and

  3. Cryosphere-hydrosphere interactions: Numerical modeling using the Regional Ocean Modeling System (ROMS) at different scales

    International Nuclear Information System (INIS)

    Bergamasco, A.; Carniel, S.; Sclavo, M.; Budgell, W.P.

    2005-01-01

    Conveyor belt circulation controls global climate through heat and water fluxes with atmosphere and from tropical to polar regions and vice versa. This circulation, commonly referred to as thermohaline circulation (THC), seems to have millennium time scale and nowadays-a non-glacial period-appears to be as rather stable. However, concern is raised by the buildup of CO 2 and other greenhouse gases in the atmosphere (IPCC, Third assessment report: Climate Change 2001. A contribution 01 working group I, n and In to the Third Assessment Report of the intergovernmental Panel on Climate Change (Cambridge Univ. Press, UK) 2001, http://www.ipcc.ch) as these may affect the THC conveyor paths. Since it is widely recognized that dense water formation sites ad as primary sources in strengthening quasi-stable THC paths (Stommel H., Tellus, 13 (1961) 224), in order to simulate properly the consequences of such scenarios a better understanding of these oceanic processes is needed. To successfully model these processes, air sea-ice-integrated modelling approaches are often required. Here we focus on two polar regions using the Regional Ocean Modeling System (ROMS). In the first region investigated, the North Atlantic-Arctic, where open-ocean Jeep convection and open-sea ire formation and dispersion under the intense air-sea interactions are the major engines, we use a new version of the coupled hydrodynamic-ice ROMS model. The second area belongs to the Antarctica region inside the Southern Ocean, where brine rejections during ice formation inside shelf seas origin dense water that, flowing along the continental slope, overflow becoming eventually abyssal waters. Results show how nowadays integrated-modelling tasks have become more and more feasible and effective; numerical simulations dealing with large computational domains or challenging different climate scenarios can be run on multi-processors platforms and on systems like LINUX clusters, made of the same hardware as PCs, and

  4. Construction and properties of a topological index for periodically driven time-reversal invariant 2D crystals

    Directory of Open Access Journals (Sweden)

    D. Carpentier

    2015-07-01

    Full Text Available We present mathematical details of the construction of a topological invariant for periodically driven two-dimensional lattice systems with time-reversal symmetry and quasienergy gaps, which was proposed recently by some of us. The invariant is represented by a gap-dependent Z2-valued index that is simply related to the Kane–Mele invariants of quasienergy bands but contains an extra information. As a byproduct, we prove new expressions for the two-dimensional Kane–Mele invariant relating the latter to Wess–Zumino amplitudes and the boundary gauge anomaly.

  5. Role of P-glycoprotein on CD69+CD4+ cells in the pathogenesis of proliferative lupus nephritis and non-responsiveness to immunosuppressive therapy.

    Science.gov (United States)

    Tsujimura, Shizuyo; Adachi, Tomoko; Saito, Kazuyoshi; Tanaka, Yoshiya

    2017-01-01

    P-glycoprotein (P-gp) expression on activated lymphocytes in systemic lupus erythematosus (SLE) plays a role in active efflux of intracellular drugs, resulting in drug resistance. The role of P-gp-expressing lymphocytes in the pathogenesis of SLE remains unclear. The aim of this study was to determine the importance of P-gp + CD4 + cells in organ manifestations in refractory SLE. The proportion of P-gp + CD4 + cells was determined by flow cytometry in peripheral blood of patients with SLE (n=116) and healthy adults (n=10). Renal biopsy specimens were examined by immunohistochemistry for P-gp expression. CD69 is a marker of CD4 cell activation. The proportion of both P-gp-expressing CD4 + cells and CD69-expressing CD4 + cells in peripheral blood was higher in SLE than control. The proportion of P-gp + CD69 + CD4 + cells correlated with Systemic Lupus Erythematosus Disease Activity Index and was higher in poor responders to corticosteroids. Furthermore, the proportion of P-gp + CD69 + CD4 + cells was significantly higher in proliferative lupus nephritis (LN) with poor response to corticosteroids. The efficacy of immunosuppressive therapy depended on the regulation of the proportion of P-gp + CD69 + CD4 + cells. Marked accumulation of P-gp + CD4 + cells in renal interstitial tissue and high proportion of peripheral P-gp + CD69 + CD4 + cells were noted in patients with proliferative LN. The results showed high proportion of P-gp + CD69 + CD4 + cells in peripheral blood and their accumulation in renal tissue in patients with proliferative LN refractory to CS therapy, suggesting that P-gp expression on activated CD4 + T cells is a potentially useful marker for refractoriness to treatment and a novel target for treatment.

  6. Marketing of Online and CD-ROM Databases.

    Science.gov (United States)

    King, Carol; Oppenheim, Charles

    1994-01-01

    A survey of 20 British electronic information vendors found that 95% considered marketing important and suggested that it is likely to become more intensive and aggressive as competition increases in the information industry. Analyzed advertisements from professional journals and direct mail literature for readability, structure, and information…

  7. Pricing Software and Information on CD-ROM.

    Science.gov (United States)

    Gibbins, Patrick

    1987-01-01

    Examines the relationships between purchases of optical data disk products, publishers, and software suppliers. The discussion covers current pricing strategies for optical data disk software and information products, and possible future developments in marketing and pricing. (CLB)

  8. The Collection Menasseh Ben Israel, CD-rom

    NARCIS (Netherlands)

    Haas, de J.J.M.; Offenberg, A.K.; Ootjers, M.G.

    1998-01-01

    The Bibliotheca Rosenthaliana, Department of Judaica and Hebraica, Amsterdam University Library, harbours many unique research collections. One of the most prominent consists of the editions printed in the seventeenth century by Menasseh Ben Israel (1604), who established the first Hebrew printing

  9. Braiding simulation for TRM preforms (CD-ROM)

    NARCIS (Netherlands)

    Akkerman, Remko; Villa Rodriguez, B.H.

    2006-01-01

    Braiding is a manufacturing process that is increasingly being used to manufacture pre-forms for Resin Transfer Moulding. A fast simulation method is presented for the prediction of the fibre distribution on complex braided parts and complex kinetic situations (e.g. changes in velocity,

  10. Korelasi Kadar Feritin dengan Jumlah CD4, CD8, dan Rasio CD4/CD8 pada Penyandang Talasemia Mayor Anak

    Directory of Open Access Journals (Sweden)

    Bonnie Arseno

    2017-11-01

    Hasil. Didapatkan jumlah CD4 absolut, CD4%, CD8 absolut dan rasio CD4/CD8 menurun. Selain itu, terdapat jumlah CD4 absolut, CD8 absolut dan CD8% meningkat. Pada kelompok usia ≤5 tahun, korelasi kadar feritin dengan CD8 absolut, CD8%, dan rasio CD4/CD8 berturut-turut menghasilkan koefisien korelasi 0,691, 0,557, -0,680, dan p<0,05. Sementara pada kelompok lama terapi ≤5 tahun korelasi kadar feritin dengan CD8 absolut, CD8%, dan rasio CD4/CD8 menghasilkan koefisien korelasi 0,709, 0,571, -0,726 dengan p<0,05. Kesimpulan. Tidak terdapat korelasi antara kadar feritin dengan jumlah CD4, CD8, rasio CD4/CD8. Peningkatan kadar feritin akan diikuti dengan peningkatan jumlah CD8 absolut dan CD8%, serta penurunan rasio CD4/CD8 pada penyandang talasemia mayor anak berdasar atas usia dan lama terapi ≤5 tahun.

  11. Asociación entre relaciones románticas y la calidad de sueño percibida por jóvenes universitarios

    OpenAIRE

    EcheverrÍa-Palacio, Carlos-Mario

    2013-01-01

    Introducción: Uno de los aspectos con mayor variación durante la adolescencia es el sueño, el cual se ve afectado por factores biológicos así como por los estados afectivos y emocionales. En esta etapa, los individuos establecen sus primeras relaciones sentimentales románticas, vínculos esenciales para la maduración de las relaciones sociales y psicosexuales. Este trabajo busca determinar la asociación existente entre las relaciones sentimentales románticas y sus características, con la calid...

  12. Optical properties of Cd Se thin films obtained by pyrolytic dew; Propiedades opticas de peliculas delgadas de CdSe obtenidas por rocio pirolitico

    Energy Technology Data Exchange (ETDEWEB)

    Perez G, A.M. [UPAEP, 72160 Puebla (Mexico); Tepantlan, C.S. [UPT, 43626 Tulancingo, Hidalgo (Mexico); Renero C, F. [INAOE, 72840 Puebla (Mexico)

    2006-07-01

    In this paper the optical properties of Cd Se thin films obtained by spray pyrolysis are presented. The films are prepared by Sodium Seleno sulphate (Na{sub 2}SSeO{sub 3}) and Cadmium Chloride (CdC{sub 12}) mixing in aqueous environment. Optical parameters of the films (refractive index, absorption coefficient and optical ban gap) were calculated from transmittance spectra. The obtained values of the optical ban gap are compared with the result obtained by other deposition method. (Author)

  13. The Clinical Significance of the MIF Homolog D-Dopachrome Tautomerase (MIF-2) and its Circulating Receptor (sCD74) in Burn Injury

    Science.gov (United States)

    Kim, Bong-Sung; Stoppe, Christian; Grieb, Gerrit; Leng, Lin; Sauler, Maor; Assis, David; Simons, David; Boecker, Arne Hendrick; Schulte, Wibke; Piecychna, Marta; Hager, Stephan; Bernhagen, Jürgen; Pallua, Norbert; Bucala, Richard

    2016-01-01

    Background We reported earlier that the cytokine macrophage migration inhibitory factor (MIF) is a potential biomarker in burn injury. In the present study, we investigated the clinical significance in severely burned patients of expression levels the newly discovered MIF family member D-dopachrome tautomerase (DDT or MIF-2) and their common soluble receptor CD74 (sCD74). Methods DDT and sCD74 serum levels were measured 20 severely burned patients and 20 controls. Serum levels were correlated to the abbreviated burn severity index (ABSI) and TBSA followed by receiver operating characteristic (ROC) analysis. Data were supported by gene expression dataset analysis of 31 burn patients and 28 healthy controls. Results CD74 and DDT were increased in burn patients. Furthermore, CD74 and DDT also were elevated in septic non-survivors when compared to survivors. Serum levels of DDT showed a positive correlation with the ABSI and TBSA in the early stage after burn injury, and the predictive character of DDT was strongest at 24 hrs. Serum levels of CD74 only correlated with the ABSI five days post-injury. Conclusions DDT may assist in the monitoring of clinical outcome and prediction of sepsis during the early post-burn period. sCD74 and MIF, by contrast, have limited value as an early predictor of death due to their delayed response to burn injury. PMID:27209369

  14. A simple model for yield prediction of rice based on vegetation index derived from satellite and AMeDAS data during ripening period

    International Nuclear Information System (INIS)

    Wakiyama, Y.; Inoue, K.; Nakazono, K.

    2003-01-01

    The present study was conducted to show a simple model for rice yield predicting by using a vegetation index (NDVI) derived from satellite and meteorological data. In a field experiment, the relationship between the vegetation index and radiation absorbed by the rice canopy was investigated from transplanting to maturity. Their correlation held. This result revealed that the vegetation index could be used as a measure of absorptance of solar radiation by rice canopy. NDVI multiplied by solar radiation (SR) every day was accumulated (Σ(SR·NDVI)) from the field experiment. Σ(SR·NDVI) was plotted against above ground dry matter. It was obvious that they had a strong relationship. Rice yield largely depends on solar radiation and air temperature during the ripening period. Air temperature affects dry matter production. Relationships between Y SR -1 (Y: rice yield, SR: solar radiation) and mean air temperature were investigated from meteorological data and statistical data on rice yield. There was an optimum air temperature, 21.3°C, for ripening. When it was near 21.3°C in the ripening period, the rice yield was higher. We proposed a simple model for yield prediction of rice based on these results. The model is composed with SR·NDVI and the optimum air temperature. Vegetation index was derived from 3 years, LANDSAT TM data in Toyama, Ishikawa, Fukui and Nagano prefectures at heading. The meteorological data was used from AMeDAS data. The model was described as follows: Y = 0.728 SR·NDVI−2.04(T−21.3) 2 + 282 (r 2 = 0.65, n = 43) where Y is rice yield (kg 10a -1 ), SR is solar radiation (MJ m -2 ) during the ripening period (from 10 days before heading to 30 days after heading), T is mean air temperature (°C) during the ripening period. RMSE was 33.7kg 10a -1 . The model revealed good precision. (author)

  15. Submesoscale Flows and Mixing in the Oceanic Surface Layer Using the Regional Oceanic Modeling System (ROMS)

    Science.gov (United States)

    2014-09-30

    IMPACT/APPLICATIONS Geochemistry and Ecosystems: An important community use for ROMS is biogeochemisty: chemical cycles, water quality, blooms ...published, refereed] Colas, F., J.C. McWilliams, X. Capet, and J. Kurian, 2012: Heat balance and eddies in the Peru- Chile Current System. Climate

  16. Proceedings of the CERI 2003 World Oil Conference : What lies beneath? CD-ROM ed.

    International Nuclear Information System (INIS)

    2003-01-01

    The 22 presentations at this conference reflected recent developments in the international petroleum industry with particular focus on the outlook of world energy markets and prospects for oil supply and reserves. Topics of discussion included the industry structure, development and operating costs, international spending, the expansion of world oil markets, market access, as well as new technology development and application. The papers also covered environmental issues such as climate change and the responsible use of water. The conference provided an opportunity for participants to discuss issues regarding oil supply and demand, oil prices, Canada's oil sands, and what role non-conventional oil plays in the current marketplace. The conference was divided into 7 sessions entitled: (1) outlook for oil prices, (2) global oil supplies, (3) oil and money, (4) downstream issues, (5) markets for Canadian bitumen and synthetics, (6) Canada's east coast, and (7) the geopolitical landscape. Three papers were indexed separately for inclusion in the database. tabs., figs

  17. CD4 Counts at Entry to HIV Care in Mexico for Patients under the “Universal Antiretroviral Treatment Program for the Uninsured Population,” 2007–2014

    Science.gov (United States)

    Hernández-Romieu, Alfonso C.; del Rio, Carlos; Hernández-Ávila, Juan Eugenio; Lopez-Gatell, Hugo; Izazola-Licea, José Antonio; Uribe Zúñiga, Patricia; Hernández-Ávila, Mauricio

    2016-01-01

    In Mexico, public health services have provided universal access to antiretroviral therapy (ART) since 2004. For individuals receiving HIV care in public healthcare facilities, the data are limited regarding CD4 T-lymphocyte counts (CD4e) at the time of entry into care. Relevant population-based estimates of CD4e are needed to inform strategies to maximize the impact of Mexico’s national ART program, and may be applicable to other countries implementing universal HIV treatment programs. For this study, we retrospectively analyzed the CD4e of persons living with HIV and receiving care at state public health facilities from 2007 to 2014, comparing CD4e by demographic characteristics and the marginalization index of the state where treatment was provided, and assessing trends in CD4e over time. Our sample included 66,947 individuals who entered into HIV care between 2007 and 2014, of whom 79% were male. During the study period, the male-to-female ratio increased from 3.0 to 4.3, reflecting the country's HIV epidemic; the median age at entry decreased from 34 years to 32 years. Overall, 48.6% of individuals entered care with a CD4≤200 cells/μl, ranging from 42.2% in states with a very low marginalization index to 52.8% in states with a high marginalization index, and from 38.9% among individuals aged 18–29 to 56.5% among those older than 50. The adjusted geometric mean (95% confidence interval) CD4e increased among males from 135 (131,142) cells/μl in 2007 to 148 (143,155) cells/μl in 2014 (p-valuewomen, with a geometric mean of 178 (171,186) and 171 (165,183) in 2007 and 2014, respectively. There have been important gains in access to HIV care and treatment; however, late entry into care remains an important barrier in achieving optimal outcomes of ART in Mexico. The geographic, socioeconomic, and demographic differences observed reflect important inequities in timely access to HIV prevention, care, and treatment services, and highlight the need to develop

  18. Refractive-index determination of solids from first- and second-order critical diffraction angles of periodic surface patterns

    International Nuclear Information System (INIS)

    Meichner, Christoph; Kador, Lothar; Schedl, Andreas E.; Neuber, Christian; Kreger, Klaus; Schmidt, Hans-Werner

    2015-01-01

    We present two approaches for measuring the refractive index of transparent solids in the visible spectral range based on diffraction gratings. Both require a small spot with a periodic pattern on the surface of the solid, collimated monochromatic light, and a rotation stage. We demonstrate the methods on a polydimethylsiloxane film (Sylgard ® 184) and compare our data to those obtained with a standard Abbe refractometer at several wavelengths between 489 and 688 nm. The results of our approaches show good agreement with the refractometer data. Possible error sources are analyzed and discussed in detail; they include mainly the linewidth of the laser and/or the angular resolution of the rotation stage. With narrow-band light sources, an angular accuracy of ±0.025 ∘ results in an error of the refractive index of typically ±5 ⋅ 10 −4 . Information on the sample thickness is not required

  19. Regulatory T Cells Show Dynamic Behavior During Late Pregnancy, Delivery, and the Postpartum Period.

    Science.gov (United States)

    Lima, Jorge; Martins, Catarina; Nunes, Glória; Sousa, Maria-José; Branco, Jorge C; Borrego, Luís-Miguel

    2017-07-01

    Regulatory T cells (Tregs) are critical immunomodulators during early pregnancy by preventing maternal T-cell activation against fetal cells. However, how populations of maternal Tregs vary during and after pregnancy in humans is still unclear. Therefore, we investigated Treg subsets in the peripheral blood of pregnant women from late pregnancy through the postpartum period. To accomplish this, the following circulating Treg subsets were analyzed in 43 healthy pregnant women and 35 nonpregnant women by flow cytometry during the third trimester, on the day of delivery, and postpartum: CD4 Dim CD25 Hi , CD4 + CD25 Hi Foxp3 + , and CD4 + CD25 Hi CD127 -/dim . Additionally, the expression levels of the transcription factor Foxp3 in CD4 Dim CD25 Hi Treg were analyzed. We have found that CD4 Dim CD25 Hi Treg subset significantly decreased in the pregnant women on the day of delivery relative to the third trimester ( P postpartum compared to the third trimester and the day of delivery ( P postpartum compared to the third trimester and the day of delivery ( P postpartum period. Our results offer an explanation for the possible effects of pregnancy on the clinical outcomes of some autoimmune diseases during the postpartum period.

  20. Delicacy, Imprecision, and Uncertainty of Oceanic Simulations: An Investigation with the Regional Oceanic Modeling System (ROMS)

    Science.gov (United States)

    2013-09-30

    Geochemistry and Ecosystems: An important community use for ROMS is biogeochemisty: chemical cycles, water quality, blooms , micro-nutrients, larval...Sci., submitted. Colas, F., J.C. McWilliams, X. Capet, and J. Kurian, 2012: Heat balance and eddies in the Peru- Chile Current System. Climate

  1. Prospectus 2000

    Science.gov (United States)

    Holmes, Jon L.; Gettys, Nancy S.

    2000-01-01

    We begin 2000 with a message about our plans for JCE Software and what you will be seeing in this column as the year progresses. Floppy Disk --> CD-ROM Most software today is distributed on CD-ROM or by downloading from the Internet. Several new computers no longer include a floppy disk drive as "standard equipment". Today's software no longer fits on one or two floppies (the installation software alone can require two disks) and the cost of reproducing and distributing several disks is prohibitive. In short, distribution of software on floppy disks is no longer practical. Therefore, JCE Software will distribute all new software publications on CD-ROM rather than on disks. Regular Issues --> Collections Distribution of all our software on CD-ROM allows us to extend our concept of software collections that we started with the General Chemistry Collection. Such collections will contain all the previously published software that is still "in print" (i.e., is compatible with current operating systems and hardware) and any new programs that fall under the topic of the collection. Proposed topics in addition to General Chemistry currently include Advanced Chemistry, Instrument and Laboratory Simulations, and Spectroscopy. Eventually, all regular issues will be replaced by these collections, which will be updated annually or semiannually with new programs and updates to existing programs. Abstracts for all new programs will continue to appear in this column when a collection or its update is ready for publication. We will continue to offer special issues of single larger programs (e.g. Periodic Table Live!, Chemistry Comes Alive! volumes) on CD-ROM and video on videotape. Connect with Your Students outside Class JCE Software has always offered network licenses to allow instructors to make our software available to students in computer labs, but that model no longer fits the way many instructors and students work with computers. Many students (or their families) own a

  2. Different thresholds of T cell activation regulate FIV infection of CD4+CD25+ and CD4+CD25- cells

    International Nuclear Information System (INIS)

    Joshi, Anjali; Garg, Himanshu; Tompkins, Mary B.; Tompkins, Wayne A.

    2005-01-01

    Cellular activation plays an important role in retroviral replication. Previously, we have shown that CD4 + CD25 + T cells by the virtue of their partially activated phenotype represent ideal candidates for a productive feline immunodeficiency virus (FIV) infection. In the present study, we extended our previous observations with regard to FIV replication in CD4 + CD25 + and CD4 + CD25 - cells under different stimulation conditions. Both CD4 + CD25 + and CD4 + CD25 - cells remain latently infected in the absence of IL-2 or concanvalinA (ConA), respectively; harboring a replication competent provirus capable of reactivation several days post-infection. While CD4 + CD25 + cells require low levels of exogenous IL-2 and virus inputs for an efficient FIV replication, CD4 + CD25 - T cells can only be productively infected in the presence of either high concentrations of IL-2 or high virus titers, even in the absence of mitogenic stimulation. Interestingly, while high virus input activates CD4 + CD25 - cells to replicate FIV, it induces apoptosis in a high percentage of CD4 + CD25 + T cells. High IL-2 concentrations but not high virus inputs lead to surface upregulation of CD25 and significant cellular proliferation in CD4 + CD25 - cells. These results suggest that CD4 + CD25 + and CD4 + CD25 - T cells have different activation requirements which can be modulated by both viral and cytokine stimuli to reach threshold activation levels in order to harbor a productive FIV infection. This holds implications in vivo for CD4 + CD25 + and CD4 + CD25 - cells to serve as potential reservoirs of a productive and latent FIV infection

  3. Expansion of CD14+CD16+ monocytes producing TNF-α in complication-free diabetes type 1 juvenile onset patients.

    Science.gov (United States)

    Myśliwska, Jolanta; Smardzewski, Marcin; Marek-Trzonkowska, Natalia; Myśliwiec, Małgorzata; Raczyńska, Krystyna

    2012-10-01

    We concentrated on the complication-free phase of juvenile onset type 1 diabetes mellitus (T1DM) searching for associations between concentration of inflammatory factors TNF-α, CRP and VEGF and two monocyte subsets the CD14(++)CD16(-) and CD14(+)CD16(+). We analysed a randomly selected group of 150 patients without complications (disease duration 2.74 ± 2.51 years) at the start of the project and 5 years later. They were compared with 24 patients with retinopathy (6.53 ± 3.39 years of disease) and 30 healthy volunteers. Our results indicate that in the complication-free period the concentration of TNF-α significantly increased and continued to increase after retinopathy was established. After 5 years the percentage and absolute number of CD14(+)CD16(+) monocytes doubled in complication-free patients. Our study indicates that the size of CD14(+)CD16(+) monocyte subset may be used alternatively to CRP values as an indicator of inflammation grade. Our results imply the necessity of trials using anti-TNF-α therapy in the complication-free phase of the disease. Copyright © 2012 Elsevier Ltd. All rights reserved.

  4. 24-hour immunologic assessment of CD4+ and CD8+ lymphocytes in renal transplant recipients receiving chronic methylprednisolone.

    Science.gov (United States)

    Tornatore, K M; Reed, K; Venuto, R

    1995-11-01

    Glucocorticoids are commonly prescribed in the post transplant period as a component of combination immunosuppressive regimens. However, the daily 24-hour pattern of helper lymphocytes (CD4+) and suppressor cells (CD8+) during chronic methylprednisolone therapy has not been examined in renal transplant recipients in relation to glucocorticoid exposure and time post-transplant. The response of total lymphocytes, CD4+ and CD8+ lymphocytes was examined in 23 stable renal transplant recipients who received methylprednisolone for at least 8 months post-transplant. The patient's prescribed oral methylprednisolone dose (mean daily dose = 9.7 +/- 2.6 mg) was given intravenously and whole blood was sampled periodically over 24 h for lymphocyte counts and methylprednisolone concentrations. A complete blood count with differential was determined via an automated hemocytometer with CD4+ and CD8+ lymphocytes determined using flow cytometry. Methylprednisolone area under the concentration versus time curve (AUC) was determined and normalized for each patient's respective dose. A general lymphopenia resulted in all patients with a mean decrease of 61 +/- 15% and an average nadir time occurring at 6 h. The decline from baseline was 76 +/- 17% for absolute number of CD4+ and 59 +/- 18% for CD8+ lymphocytes with an average nadir time at 6 h. Twelve patients exhibited a baseline CD4+ count to be less than 688 cells/mm3 (the low end of the reference range) and the lymphocyte count of all the patients fell below this value at the nadir. Six patients had a CD8+ lymphocyte count below 380 cells/mm3 (low end of the reference range) at baseline with 21 of the 23 patients exhibiting less than 380 cells/mm3 at the nadir time. At the time of nadir, the mean CD4+ and CD8+ counts were 156 +/- 105 cells/mm3 and 256 +/- 270 cells/mm3, respectively. In 17 of the 23 patients, the CD4+ count was below 200 cells/mm3 at the time of nadir. The dose-normalized AUC of methylprednisolone ranged from 22

  5. Distribution of intrahepatic T, NK and CD3(+)CD56(+)NKT cells alters after liver transplantation: Shift from innate to adaptive immunity?

    Science.gov (United States)

    Werner, Jens M; Lang, Corinna; Scherer, Marcus N; Farkas, Stefan A; Geissler, Edward K; Schlitt, Hans J; Hornung, Matthias

    2011-07-01

    The liver is an immunological organ containing a large number of T, NK and NKT cells, but little is known about intrahepatic immunity after LTx. Here, we investigated whether the distribution of T, NK and CD3(+)CD56(+)NKT cells is altered in transplanted livers under different circumstances. Core biopsies of transplanted livers were stained with antibodies against CD3 and CD56. Several cell populations including T (CD3(+)CD56(-)), NK (CD3(-)CD56(+)) and NKT cells (CD3(+)CD56(+)) were studied by fluorescence microscopy. Cell numbers were analyzed in relation to the time interval after LTx, immunosuppressive therapy and stage of acute graft rejection (measured with the rejection activity index: RAI) compared to tumor free liver tissue from patients after liver resection due to metastatic disease as control. Recruitment of CD3(+)CD56(+)NKT cells revealed a significant decrease during high RAI scores in comparison to low and middle RAI scores (RAI 7-9: 0.03±0.01/HPF vs. RAI 4-6: 0.1±0.005/HPF). CD3(+)CD56(+)NKT cells were also lower during immunosuppressive therapy with tacrolimus (0.03±0.01/HPF) than with cyclosporine (0.1±0.003/HPF), cyclosporine/MMF (0.1±0.003/HPF) or sirolimus (0.1±0.01/HPF) treatment. Intrahepatic T cell numbers increased significantly 50days after LTx compared to control liver tissue (4.5±0.2/HPF vs. 1.9±0.1/HPF). In contrast, NK cells (0.3±0.004/HPF) were significantly fewer in all biopsies after LTx compared to the control (0.7±0.04/HPF). These data indicate significant alterations in the hepatic recruitment of T, NK and CD3(+)CD56(+)NKT cells after LTx. The increase in T cells and the decrease in NK and CD3(+)CD56(+)NKT cells suggest a shift from innate to adaptive hepatic immunity in the liver graft. Copyright © 2011 Elsevier B.V. All rights reserved.

  6. Effect of Ankle Range of Motion (ROM) and Lower-Extremity Muscle Strength on Static Balance Control Ability in Young Adults: A Regression Analysis

    Science.gov (United States)

    Kim, Seong-Gil

    2018-01-01

    Background The purpose of this study was to investigate the effect of ankle ROM and lower-extremity muscle strength on static balance control ability in young adults. Material/Methods This study was conducted with 65 young adults, but 10 young adults dropped out during the measurement, so 55 young adults (male: 19, female: 36) completed the study. Postural sway (length and velocity) was measured with eyes open and closed, and ankle ROM (AROM and PROM of dorsiflexion and plantarflexion) and lower-extremity muscle strength (flexor and extensor of hip, knee, and ankle joint) were measured. Pearson correlation coefficient was used to examine the correlation between variables and static balance ability. Simple linear regression analysis and multiple linear regression analysis were used to examine the effect of variables on static balance ability. Results In correlation analysis, plantarflexion ROM (AROM and PROM) and lower-extremity muscle strength (except hip extensor) were significantly correlated with postural sway (pregression analysis, plantar flexion PROM with eyes open significantly influenced sway length (B=0.681) and sway velocity (B=0.011). Conclusions Lower-extremity muscle strength and ankle plantarflexion ROM influenced static balance control ability, with ankle plantarflexion PROM showing the greatest influence. Therefore, both contractile structures and non-contractile structures should be of interest when considering static balance control ability improvement. PMID:29760375

  7. Are you dyslexic?

    CERN Multimedia

    2003-01-01

    If so, read this article. You may be able to help children with the same disability as you. The BBC and the charity Dyslexia International Tools and Technologies (DITT) are currently producing a CD-ROM for dyslexic children aged 9 to 14. One of the aims is to offer them encouragement by showing them that people with dyslexia have made successes of their lives. The BBC is therefore looking for people from all over Europe who have succeeded despite their condition. The CD-ROM will be translated into several different languages and distributed throughout Europe. If you are a high-level physicist with dyslexia, you could take part in the making of this CD-Rom. The BBC will be coming to film 10-minute interviews about people's experience with dyslexia and the advice they can offer to young people suffering from the same condition. Please send an e-mail to James.Gillies@cern.ch as soon as possible.

  8. EOSDIS Terra Data Sampler #1: Western US Wildfires 2000. 1.1

    Science.gov (United States)

    Perkins, Dorothy C. (Technical Monitor)

    2000-01-01

    This CD-ROM contains sample data in HDF-EOS format from the instruments on board the Earth Observing System (EOS) Terra satellite: (1) Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER); (2) Clouds and the Earth's Radiant Energy System (CERES); (3) Multi-angle Imaging Spectroradiometer (MISR); and (4) Moderate Resolution Imaging Spectroradiometer (MODIS). Data from the Measurements of Pollution in the Troposphere (MOPITT) instrument were not available for distribution (as of October 17, 2000). The remotely sensed, coincident data for the Western US wildfires were acquired August 30, 2000. This CD-ROM provides information about the Terra mission, instruments, data, and viewing tools. It also provides the Collage tool for viewing data, and links to Web sites containing other digital data processing software. Full granules of the data on this CD-ROM and other EOS Data and Information System (EOSDIS) data products are available from the NASA Distributed Active Archive Centers (DAACs).

  9. Optical properties of P3HT:tributylphosphine oxide-capped CdSe nanocomposites

    Energy Technology Data Exchange (ETDEWEB)

    Benchaabane, A. [Faculte des Sciences d' Amiens, Laboratoire de Physique de la Matiere Condensee, Amiens (France); Universite Tunis El-Manar, Laboratoire de Materiaux avances et phenomenes quantiques, Faculte des Sciences de Tunis El Manar, Tunis (Tunisia); Universite Arabe des Sciences, Ecole Superieure d' Ingenieurs et des Etudes Technologiques, Tunis (Tunisia); Ben Hamed, Z.; Kouki, F.; Bouchriha, H. [Universite Tunis El-Manar, Laboratoire de Materiaux avances et phenomenes quantiques, Faculte des Sciences de Tunis El Manar, Tunis (Tunisia); Lahmar, A.; Zellama, K.; Zeinert, A. [Faculte des Sciences d' Amiens, Laboratoire de Physique de la Matiere Condensee, Amiens (France); Sanhoury, M.A. [Laboratoire de Chimie Organique Structurale, Synthese et Etudes Physicochimiques, Tunis (Tunisia)

    2016-08-15

    The optical properties of nanocomposite layers prepared by incorporation of tributylphosphine oxide (TBPO)-capped CdSe nanocrystals (NCs) in a P3HT polymer matrix are studied using different nanocrystal concentrations. Reflection spectra analyzed through Kim oscillator model lead to the determination of optical constants such as refractive index n, extinction coefficient k, dielectric permittivity ε and absorption coefficient α. Using the common Cauchy, Drude-Lorentz, Tauc and single-effective-oscillator theoretical models, we have determined the values of static refractive index n{sub s} and permittivity ε{sub s}, plasma frequency ω{sub p}, carrier density N, optical band gap E{sub g} and oscillator and dispersion energies E{sub 0} and E{sub d}, respectively. It is found that TBPO-capped CdSe NCs concentration affects the optoelectronic parameters of the nanocomposite thin films. Moreover, the disorder of this hybrid system is also studied by the determination of Urbach energy, which increases with TBPO-capped CdSe concentration. (orig.)

  10. Mi-spillet

    DEFF Research Database (Denmark)

    Larsen, Lea Lund; Hejlesen, Stine

    2003-01-01

    MI-spillet er et undervisningsspil til folkeskolens mellemtrin og udskolingen. Spillet omformer Howard Gardners teori om de mange intelligenser til et praktisk og håndgribeligt værktøj til brug i folkeskolen. Spillet indeholder et undervisningsmateriale bestående af lærervejledning og kopimappe...... emnebaseret eller tværfagligt arbejde. Alt materialet ligger samlet på en cd-rom, hvorfra materialet printes. Skolen kan derfor ved køb af én cd-rom printe og producere et ubegrænset antal spil. Cd-rommen indeholder: 1. Lærervejledning 2. MI-spillet * Gulvpladerne * Spørgsmål til spillet * Bilag til...

  11. Comparative investigation of toxicity and bioaccumulation of Cd-based quantum dots and Cd salt in freshwater plant Lemna minor L.

    Science.gov (United States)

    Modlitbová, Pavlína; Novotný, Karel; Pořízka, Pavel; Klus, Jakub; Lubal, Přemysl; Zlámalová-Gargošová, Helena; Kaiser, Jozef

    2018-01-01

    The purpose of this study was to determine the toxicity of two different sources of cadmium, i.e. CdCl 2 and Cd-based Quantum Dots (QDs), for freshwater model plant Lemna minor L. Cadmium telluride QDs were capped with two coating ligands: glutathione (GSH) or 3-mercaptopropionic acid (MPA). Growth rate inhibition and final biomass inhibition of L. minor after 168-h exposure were monitored as toxicity endpoints. Dose-response curves for Cd toxicity and EC50 168h values were statistically evaluated for all sources of Cd to uncover possible differences among the toxicities of tested compounds. Total Cd content and its bioaccumulation factors (BAFs) in L. minor after the exposure period were also determined to distinguish Cd bioaccumulation patterns with respect to different test compounds. Laser-Induced Breakdown Spectroscopy (LIBS) with lateral resolution of 200µm was employed in order to obtain two-dimensional maps of Cd spatial distribution in L. minor fronds. Our results show that GSH- and MPA-capped Cd-based QDs have similar toxicity for L. minor, but are significantly less toxic than CdCl 2 . However, both sources of Cd lead to similar patterns of Cd bioaccumulation and distribution in L. minor fronds. Our results are in line with previous reports that the main mediators of Cd toxicity and bioaccumulation in aquatic plants are Cd 2+ ions dissolved from Cd-based QDs. Copyright © 2017 Elsevier Inc. All rights reserved.

  12. Interferometric investigation and simulation of refractive index in glass matrixes containing nanoparticles of varying sizes

    Energy Technology Data Exchange (ETDEWEB)

    Feeney, Michael Gerard; Ince, Rabia; Yukselici, Mehmet Hikmet; Allahverdi, Cagdas

    2011-07-01

    The relationship between refractive index and nanoparticle radii of cadmium selenide (CdSe) nanoparticles embedded within glass matrixes was investigated experimentally and by simulations. A homemade automated Michelson interferometer arrangement employing a rotating table and a He-Ne laser source at a wavelength of 632.8 nm determined the refractive index versus nanoparticle radii of embedded cadmium selenide (CdSe) nanoparticles. The refractive index was found to decrease linearly with nanoparticle radius increase. However, one sample showed a step increase in refractive index; on spectroscopic analysis, it was found that its resonant wavelength matched that of the He-Ne source wavelength. The simulations showed that two conditions caused the step increase in refractive index: low plasma frequency and matched sample and source resonances. This simple interferometer setup defines a new method of determining the radii of nanoparticles embedded in substrates and enables refractive index tailoring by modification of exact annealing conditions.

  13. [Does routine outcome monitoring have a promising future? An investigation into the use of shared decision-making combined with ROM for patients with a combination of physical and psychiatric symptoms].

    Science.gov (United States)

    van der Feltz-Cornelis, C M; Andrea, H; Kessels, E; Duivenvoorden, H J; Biemans, H; Metz, M

    2014-01-01

    Although routine outcome monitoring (ROM) has been developed and widely used in the course of patient centered outcome research in the Netherlands, so far the technique has hardly ever been used to improve the treatment of individual patients. To describe how a rom technique based on the principles of shared decision-making (SDM) was developed and evaluated at the Center for Body, Mind and Health at GGz Breburg, a specialised mental health institution in the Netherlands. We have developed a conceptual model for SDM that involves patient participation and the use of evidence-based decision-aids with cut-off scores. According to the conceptual model for SDM that we developed, the patient and the health professional involved took 'shared' decisions in three phases; the decisions related to triage, the drawing-up of a treatment plan and a follow-up treatment course. At the end of the 6 month intake-phase 7 of the 67 patients who were deemed eligible for ROM/SDM were dropped from the study because they were incapable of performing ROM assessments. Due to diagnostic advice and referral at the end of the intake-phase, 25 patients did not require further treatment. Of the remaining 35 patients, 33 delivered at least one follow-up ROM assessment during the subsequent treatment phases. In these patients somatic and psychiatric symptoms were found to be significantly reduced. ROM combined with sdm can be used successfully with patients who have a combination of physical and psychiatric symptoms and the technique can be applied by the professional in charge. Very few patients dropped out of the follow-up measurements and somatic as well as depressive or psychiatric symptoms diminished significantly. These findings indicate that a Randomised Clinical Trial is warranted in order to test the effectiveness of sdm combined with ROM as a decision-making instrument.

  14. Oil and Gas field code master list 1995

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-12-01

    This is the fourteenth annual edition of the Energy Information Administration`s (EIA) Oil and Gas Field Code Master List. It reflects data collected through October 1995 and provides standardized field name spellings and codes for all identified oil and/or gas fields in the US. The Field Code Index, a listing of all field names and the States in which they occur, ordered by field code, has been removed from this year`s publications to reduce printing and postage costs. Complete copies (including the Field Code Index) will be available on the EIA CD-ROM and the EIA World-Wide Web Site. Future editions of the complete Master List will be available on CD-ROM and other electronic media. There are 57,400 field records in this year`s Oil and Gas Field Code Master List. As it is maintained by EIA, the Master List includes the following: field records for each State and county in which a field resides; field records for each offshore area block in the Gulf of Mexico in which a field resides; field records for each alias field name (see definition of alias below); and fields crossing State boundaries that may be assigned different names by the respective State naming authorities. Taking into consideration the double-counting of fields under such circumstances, EIA identifies 46,312 distinct fields in the US as of October 1995. This count includes fields that no longer produce oil or gas, and 383 fields used in whole or in part for oil or gas Storage. 11 figs., 6 tabs.

  15. Total hip arthroplasty (S-ROM stem and subtrochanteric osteotomy for Crowe type IV developmental dysplasia of the hip

    Directory of Open Access Journals (Sweden)

    Liangtao Li

    2016-01-01

    Conclusions: In the primary THA for the treatment of irreducible DDH, subtrochanteric oblique osteotomy combined with the freely-rotatable S-ROM stem provided favorable short term outcomes by affording both morphological and functional advantages.

  16. Managing nuclear knowledge: IAEA activities and international coordination. Asian Network for Education in Nuclear Technology (ANENT)

    International Nuclear Information System (INIS)

    2007-07-01

    This CD-ROM is attached to the booklet 'Managing nuclear knowledge: IAEA activities and international coordination. Asian Network for Education in Nuclear Technology (ANENT)'. It contains the background material with regard to ANENT in full text, including policy level papers, reports, presentation material made by Member States, and meeting summaries during the period 2002-2005. Further information on the current ANENT activities and related IAEA activities is available at 'http://anent-iaea.org' and 'http://iaea.org/inisnkm'

  17. Reprocessing of multi-channel seismic-reflection data collected in the Chukchi Sea

    Science.gov (United States)

    Agena, W.F.; Lee, M.W.; Hart, P.E.

    2001-01-01

    Contained on this set of two CD-ROMs are stacked and migrated multi-channel seismic-reflection data for 44 lines recorded in the Chukchi Sea, northern Alaska, by the United States Geological Survey in 1977, 1978, and 1980. All data were reprocessed by the USGS in 2000 using updated methods. The resulting final data have both increased temporal and spatial resolution thus providing improved interpretability. An added benefit of these CD-ROMs is that they are a more stable, long-term archival medium for the data.

  18. The comparison of heavy metals (Pb and Cd) in the water and sediment during spring and neap tide tidal periods in Popoh Bay, Indonesia

    Science.gov (United States)

    Yona, D.; Febriana, R.; Handayani, M.

    2018-04-01

    This study attempted to investigate different concentration of lead (Pb) dan cadmium (Cd) in the water and sediment during spring and neap tidal periods in the Popoh Bay, Indonesia. Water and sediment samples were taken during spring and neap tides from eight sampling stations in the study area. The result shows higher concentration of Pb than the concentration of Cd in both spring and neap tides due to higher input of Pb from the oil pollution by boat and fisheries activities. Pb concentrations were doubled during neap tide in both water and sediments with the value of 0.51 and 0.28 ml/L in the water during neap and spring tide, respectively; and 0.27 ppm and 0.16 mg/kg in the sediment during neap and spring tide, respectively. On the other hand, Cd concentrations in the water were found in almost similar values between spring and neap tide (0.159 and 0.165 ml/L in spring tide and neap tide, respectively), but in the sediment, the concentration was a little higher during spring tide (0.09 and 0.05 mg/kg during spring and neap tide, respectively). This study shows that water movement during spring and neap tides has significant effect on the distribution of heavy metals.

  19. Determination of normal expression patterns of CD86, CD210a, CD261, CD262, CD264, CD358, and CD361 in peripheral blood and bone marrow cells by flow cytometry.

    Science.gov (United States)

    Rudolf-Oliveira, Renata Cristina Messores; Auat, Mariangeles; Cardoso, Chandra Chiappin; Santos-Pirath, Iris Mattos; Lange, Barbara Gil; Pires-Silva, Jéssica; Moraes, Ana Carolina Rabello de; Dametto, Gisele Cristina; Pirolli, Mayara Marin; Colombo, Maria Daniela Holthausen Périco; Santos-Silva, Maria Claudia

    2018-02-01

    In 2010, new monoclonal antibodies were submitted to the 9th International Workshop on Human Leukocyte Differentiation Antigens, and there are few studies demonstrating normal expression patterns of these markers. Thus, the objective of this study was to determine the normal patterns of cell expression of CD86, CD210a, CD261, CD262, CD264, CD358, and CD361 in peripheral blood (PB) and bone marrow (BM) samples by flow cytometry. In the present study, CD86 was expressed only in monocytes and B lymphocytes in PB and in monocytes and plasma cells in BM. Regarding CD210a expression, in PB samples, monocytes and NK cells showed weak expression, while neutrophils, B and T lymphocytes, and basophils showed weak and partial expression. In BM samples, expression of CD210a was observed in eosinophils, monocytes, and B and T/NK lymphocytes. Weak expression of CD210a was also observed in neutrophilic cells and plasma cells. All B cell maturation stages had weak expression of CD210a except for immature B cells, which did not express this marker. In the present study, no cell type in PB samples showed positivity for CD261 and, in BM samples, there was very weak expression in neutrophilic series, monocytes, and B lymphocytes. Conversely, plasma cells showed positivity for CD261 with a homogeneous expression. For CD262, there was weak expression in monocytes, neutrophils, and B lymphocytes in PB samples and weak expression in monocytes, B lymphocytes, and plasma cells in BM samples. The evaluation of CD264 showed very weak expression in B cells in PB samples and no expression in BM cells. Very weak expression of CD358 was observed in neutrophils, monocytes, and B lymphocytes in PB and BM samples. In addition, in BM samples, plasma cells and T lymphocytes showed weak expression of CD358. In relation to the maturation stages of B cells, there was weak expression in pro-B cel, pre-B cell, and mature B cell. In the present study, it was possible to observe expression of CD361 in all

  20. Post-mortal changes in blood Cd levels in consideration of Cd levels in organs. Postmortale Veraenderung der Cadmiumkonzentration im Blut unter Beruecksichtigung der Organcadmiumkonzentrationen

    Energy Technology Data Exchange (ETDEWEB)

    Goetz, D.

    1987-09-04

    After a detailed introduction, in which the properties and occurrence of Cd, the Cd metabolism and the Cd concentration in blood and organs, and the effects of smoking are discussed, the author presents the results of Cd concentration measurements in the biological materials of a collective of patients who died in the intensive care unit of an internal ward. In all cases, the postmortal Cd concentration in venal blood was much higher than the in-vivo concentration. The concentration increase is not noticeable in the first two hours post mortem; from the forensic view, it is therefore recommended to sample blood as early as possible in case of suspected Cd poisoning. After a latency period of 38 to 92 h, intracardial blood Cd concentrations will be high enough to suspect Cd intoxication, or at least a very high Cd exposure. This tentative diagnosis of Cd intoxication can be proved or disproved only by the rather tedions measurement of Cd concentrations in organs. Postmortal toxicological blood screening should, therefore, not lead to hasty conclusions. The contribution of smoking to Cd concentrations was clearly proved by comparisons of blood Cd concentrations and organ Cd concentrations of smokers and nonsmokers.

  1. Slow-release nitrogen fertilizers can improve yield and reduce Cd concentration in pakchoi (Brassica chinensis L.) grown in Cd-contaminated soil.

    Science.gov (United States)

    Zhang, Ran-Ran; Liu, Yue; Xue, Wan-Lei; Chen, Rong-Xin; Du, Shao-Ting; Jin, Chong-Wei

    2016-12-01

    Cadmium (Cd) pollution in vegetable crops has become a serious problem in recent years. Owing to the limited availability of arable land resources, large areas of Cd-contaminated lands are inevitably being used for the production of vegetables, posing great risks to human health via the food chain. However, strategies to improve yield and reduce Cd concentration in crops grown in contaminated soils are being developed. In the present study, using pot experiments, we investigated the effects of two slow-release nitrogen fertilizers (SRNFs), resin-coated ammonium nitrate (Osmocote 313s ), and resin-coated urea (urea 620 ), on the growth and Cd concentration of the Cd-contaminated pakchoi. The results showed that pakchoi grown in soil containing 5 mg kg -1 of Cd-induced oxidative stress (indicated by malondialdehyde (MDA), H 2 O 2 , and O 2 ·- ) and photosynthesis inhibition, which in turn was restored with the application of SRNFs. However, pakchoi grown in Cd-contaminated soil supplied with Osmocote 313s and urea 620 showed 103 and 203 % increase in fresh weight and 51-55 % and 44-56 % decrease in Cd concentration, respectively, as compared with their controls (pakchoi treated with instant soluble nitrogen fertilizers). On the basis of an increase in their tolerance index (47-238 %) and a decrease in their translocation factor (7.5-21.6 %), we inferred that the plants treated with SRNFs have a stronger tolerance to Cd and a lower efficiency of Cd translocation to edible parts than those treated with instant soluble nitrogen fertilizers. Therefore, in terms of both crop production and food safety, application of SRNFs could be an effective strategy for improving both biomass production and quality in pakchoi grown under Cd stress.

  2. Serum CD73 and apelin levels in patients with diabetic retinopathy and the clinical significance

    Institute of Scientific and Technical Information of China (English)

    Wei-Qiang Du

    2017-01-01

    Objective:To study the serum ecto-5'-nucleotidase (CD73) and apelin levels in patients with diabetic retinopathy (DR) and the clinical significance.Methods:A total of 108 patients with type 2 diabetes treated in our hospital between April 2013 and February 2016 were collected and divided into non-diabetic retinopathy (NDR) group (n=51), background diabetic retinopathy (BDR) group (n=40) and proliferative diabetic retinopathy (PDR) group (n=17) based on the results of fundus fluorescence angiography. Enzyme-linked immunosorbent assay (ELISA) was used to determine CD73 and apelin level immediately after admission; thiobarbituric acid method and xanthine oxidase method were used to determine the serum levels of oxidative stress indicators; ELISA method was used to determine the levels of angiogenesis indexes and inflammatory factors; Pearson test was used to analyze the correlation of serum CD73 and apelin levels with the illness-related indexes in patients with DR.Results:Serum CD73 and apelin levels of BDR group and PDR group were significantly higher than those of NDR group, and serum CD73 and apelin levels of PDR group were significantly higher than those of BDR group; serum malondialdehyde (MDA), advanced oxidation protein products (AOPP), interleukin-2 (IL-2), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), hypersensitive C-reactive protein (hs-CRP), vascular endothelial growth factor (VEGF), angiogenin-2 (Ang-2) and hypoxia-inducible factor 1α (HIF-1α) levels of BDR group and PDR group were significantly higher than those of NDR group while total antioxidant capacity (TAOC), superoxide dismutase (SOD) and interleukin-10 (IL-10) levels were lower than those of NDR group, and the changes in above indexes of PDR group were more significant; Pearson test showed that serum CD73 and apelin levels in patients with DR were directly correlated with the levels of illness-related indexes.Conclusion:CD73 and apelin expression are abnormally high in patients with

  3. Serum CD73 and apelin levels in patients with diabetic retinopathy and the clinical significance

    Directory of Open Access Journals (Sweden)

    Wei-Qiang Du

    2017-04-01

    Full Text Available Objective: To study the serum ecto-5'-nucleotidase (CD73 and apelin levels in patients with diabetic retinopathy (DR and the clinical significance. Methods: A total of 108 patients with type 2 diabetes treated in our hospital between April 2013 and February 2016 were collected and divided into non-diabetic retinopathy (NDR group (n=51, background diabetic retinopathy (BDR group (n=40 and proliferative diabetic retinopathy (PDR group (n=17 based on the results of fundus fluorescence angiography. Enzyme-linked immunosorbent assay (ELISA was used to determine CD73 and apelin level immediately after admission; thiobarbituric acid method and xanthine oxidase method were used to determine the serum levels of oxidative stress indicators; ELISA method was used to determine the levels of angiogenesis indexes and inflammatory factors; Pearson test was used to analyze the correlation of serum CD73 and apelin levels with the illness-related indexes in patients with DR. Results: Serum CD73 and apelin levels of BDR group and PDR group were significantly higher than those of NDR group, and serum CD73 and apelin levels of PDR group were significantly higher than those of BDR group; serum malondialdehyde (MDA, advanced oxidation protein products (AOPP, interleukin-2 (IL-2, interleukin-6 (IL-6, tumor necrosis factor-毩 (TNF- 毩, hypersensitive C-reactive protein (hs-CRP, vascular endothelial growth factor (VEGF, angiogenin-2 (Ang-2 and hypoxia-inducible factor 1毩 (HIF-1毩 levels of BDR group and PDR group were significantly higher than those of NDR group while total antioxidant capacity (TAOC, superoxide dismutase (SOD and interleukin-10 (IL-10 levels were lower than those of NDR group, and the changes in above indexes of PDR group were more significant; Pearson test showed that serum CD73 and apelin levels in patients with DR were directly correlated with the levels of illness-related indexes. Conclusion: CD73 and apelin expression are abnormally high in

  4. The Importance of CD56 and CD98 Levels in Patients with Recurrent Implantation Failure

    Directory of Open Access Journals (Sweden)

    Tevfik Berk Bildaci

    2017-05-01

    Full Text Available Aim: Despite major advances in assisted reproductive techniques, clinical pregnancy rates remain around 31% with fresh embryo transfer and around 41% with oocyte donations. We also know that the implantation process itself and the window period defined as the %u2018%u2019implantation phase%u2019%u2019 are significantly important for successful in-vitro fertilization (IVF cycles. With this study we have tried to determine any differences in immunohistochemical staining for CD56 and CD98 within the implantation phase endometrium of patients with recurrent implantation failure and of a control group that eventually had a successful IVF cycle. Material and Method: This study was retrospectively performed on a total of 36 patients selected out of a database of 6260 patients who received their IVF cycles from 2004 to 2010. Patients were defined as implantation failure if they did not have a positive result for b-HCG testing following at least 3 IVF cycles with a total of at least 8 embryo transfers. The control group was formed with patients who had success (positive b-HCG testing on their first IVF treatment. Results: Comparison of means for CD 56 staining percentages, CD 98 staining percentages, CD 98 staining power, and CD 98 staining score showed significant difference between the control group and the study group (p

  5. Solar, interplanetary and terrestrial features associated with periods of prolonged positive and negative Dst index

    International Nuclear Information System (INIS)

    Rajaram, G.

    1989-01-01

    From a survey of the published final values of the geomagnetic index D st for the period 1958-1972, we found long time intervals of over 25-30 days, during which this index remained consistently positive (D st +) or negative (D st -). A study is made of relevant parameters on the ground, in the magnetosphere, in the solar wind and on the Sun to seek out systematic features associated with the two conditions. In order to eliminate factors arising from seasonal and solar cycle variations, we selected pairs of D st + and D st - which involve successive months of the same year, or the same month of two successive years. Three parameters which show a systematic difference between D st + and D st - intervals are found to be 1) the state of solar photospheric magnetic fields 2) the flux density of solar MeV protons measured in the magnetosphere and 3) the southward component of the interplanetary magnetic field. While the effect of the last on geomagnetic activity has been well-discussed in the literature, it is suggested that the correlations of the first two to the conditions of D st + and D st - demand a careful scrutiny of the solar-terrestrial relationship. (author)

  6. Diastereoselective Synthesis of Novel Heterocyclic Scaffolds through Tandem Petasis 3-Component/Intramolecular Diels-Alder and ROM-RCM Reactions

    DEFF Research Database (Denmark)

    Ishøy, Mette; Petersen, Rico; Petersen, Michael Åxman

    2017-01-01

    A high-yielding, stereoselective and extraordinarily complexity generatingPetasis 3-component/intramolecular Diels-Alderreaction has been developed. In combination with ROM-RCM, rapid access to complex sp3-rich heterocyclic scaffolds amenableto subsequent functionalization and library synthesis...

  7. CD80 and CD86 Costimulatory Molecules Differentially Regulate OT-II CD4+ T Lymphocyte Proliferation and Cytokine Response in Cocultures with Antigen-Presenting Cells Derived from Pregnant and Pseudopregnant Mice

    Directory of Open Access Journals (Sweden)

    Tomasz Maj

    2014-01-01

    Full Text Available Immune phenomena during the preimplantation period of pregnancy are poorly understood. The aim of our study was to assess the capacity for antigen presentation of splenic antigen-presenting cells (APCs derived from pregnant and pseudopregnant mice in in vitro conditions. Therefore, sorted CD11c+ dendritic cells and macrophages F4/80+ and CD11b+ presenting ovalbumin (OVA were cocultured with CD4+ T cells derived from OT-II mice’s (C57BL6/J-Tg(TcraTcrb1100Mjb/J spleen. After 132 hours of cell culture, proliferation of lymphocytes (ELISA-BrdU, activation of these cells (flow cytometry, cytokine profile (ELISA, and influence of costimulatory molecules blocking on these parameters were measured. We did not detect any differences in regulation of Th1/Th2 cytokine balance. CD86 seems to be the main costimulatory molecule involved in the proliferation response but CD80 is the main costimulatory molecule influencing cytokine secretion in pregnant mice. In conclusion, this study showed that CD80 and CD86 costimulatory molecules regulate OT-II CD4+ T lymphocyte proliferation and cytokine response in cocultures with antigen-presenting cells derived from pregnant and pseudopregnant mice. The implications of these changes still remain unclear.

  8. Using a Multimedia Tool to Improve Cardiac Auscultation Knowledge and Skills

    Science.gov (United States)

    Stern, David T; Mangrulkar, Rajesh S; Gruppen, Larry D; Lang, Angela L; Grum, Cyril M; Judge, Richard D

    2001-01-01

    OBJECTIVE Today's medical school graduates have significant deficits in physical examination skills. Medical educators have been searching for methods to effectively teach and maintain these skills in students. The objective of this study was to determine if an auscultation curriculum centered on a portable multimedia CD-ROM was effective in producing and maintaining significant gains in cardiac auscultatory skills. DESIGN Controlled cohort study PARTICIPANTS All 168 third-year medical students at 1 medical school in an academic medical center. INTERVENTIONS Students were tested before and after exposure to 1 or more elements of the auscultation curriculum: teaching on ward/clinic rotations, CD-ROM comprehensive cases with follow-up seminars, and a CD-ROM 20-case miniseries. The primary outcome measures were student performance on a 10-item test of auscultation skill (listening and identifying heart sound characteristics) and a 30-item test of auscultation knowledge (factual questions about auscultation). A subset of students was tested for attenuation effects 9 or 12 months after the intervention. RESULTS Compared with the control group (1 month clinical rotation alone), students who were also exposed to the CD-ROM 20-case miniseries had significant improvements in auscultation skills scores (P auscultation knowledge beyond the miniseries alone (P auscultation skills. Students' auscultation knowledge diminished one year after the intervention, but auscultation skills did not. CONCLUSION In addition to the standard curriculum of ward and conference teaching, portable multimedia tools may help improve quality of physical examination skills. PMID:11722691

  9. Effect of Ankle Range of Motion (ROM) and Lower-Extremity Muscle Strength on Static Balance Control Ability in Young Adults: A Regression Analysis.

    Science.gov (United States)

    Kim, Seong-Gil; Kim, Wan-Soo

    2018-05-15

    BACKGROUND The purpose of this study was to investigate the effect of ankle ROM and lower-extremity muscle strength on static balance control ability in young adults. MATERIAL AND METHODS This study was conducted with 65 young adults, but 10 young adults dropped out during the measurement, so 55 young adults (male: 19, female: 36) completed the study. Postural sway (length and velocity) was measured with eyes open and closed, and ankle ROM (AROM and PROM of dorsiflexion and plantarflexion) and lower-extremity muscle strength (flexor and extensor of hip, knee, and ankle joint) were measured. Pearson correlation coefficient was used to examine the correlation between variables and static balance ability. Simple linear regression analysis and multiple linear regression analysis were used to examine the effect of variables on static balance ability. RESULTS In correlation analysis, plantarflexion ROM (AROM and PROM) and lower-extremity muscle strength (except hip extensor) were significantly correlated with postural sway (psimple correlation analysis, all variables that passed the correlation analysis procedure had significant influence (plinear regression analysis, plantar flexion PROM with eyes open significantly influenced sway length (B=0.681) and sway velocity (B=0.011). CONCLUSIONS Lower-extremity muscle strength and ankle plantarflexion ROM influenced static balance control ability, with ankle plantarflexion PROM showing the greatest influence. Therefore, both contractile structures and non-contractile structures should be of interest when considering static balance control ability improvement.

  10. Optical properties of Cd Se thin films obtained by pyrolytic dew

    International Nuclear Information System (INIS)

    Perez G, A.M.; Tepantlan, C.S.; Renero C, F.

    2006-01-01

    In this paper the optical properties of Cd Se thin films obtained by spray pyrolysis are presented. The films are prepared by Sodium Seleno sulphate (Na 2 SSeO 3 ) and Cadmium Chloride (CdC 12 ) mixing in aqueous environment. Optical parameters of the films (refractive index, absorption coefficient and optical ban gap) were calculated from transmittance spectra. The obtained values of the optical ban gap are compared with the result obtained by other deposition method. (Author)

  11. CD4+/CD8+ double-positive T cells

    DEFF Research Database (Denmark)

    Overgaard, Nana H; Jung, Ji-Won; Steptoe, Raymond J

    2015-01-01

    CD4(+)/CD8(+) DP thymocytes are a well-described T cell developmental stage within the thymus. However, once differentiated, the CD4(+) lineage or the CD8(+) lineage is generally considered to be fixed. Nevertheless, mature CD4(+)/CD8(+) DP T cells have been described in the blood and peripheral...... cells, CD4(+)/CD8(+) T cell populations, outside of the thymus, have recently been described to express concurrently ThPOK and Runx3. Considerable heterogeneity exists within the CD4(+)/CD8(+) DP T cell pool, and the function of CD4(+)/CD8(+) T cell populations remains controversial, with conflicting...... reports describing cytotoxic or suppressive roles for these cells. In this review, we describe how transcriptional regulation, lineage of origin, heterogeneity of CD4 and CD8 expression, age, species, and specific disease settings influence the functionality of this rarely studied T cell population....

  12. Increased Range of Motion Is Important for Functional Outcome and Satisfaction After Total Knee Arthroplasty in Asian Patients.

    Science.gov (United States)

    Ha, Chul-Won; Park, Yong-Beom; Song, Young-Suk; Kim, Jun-Ho; Park, Yong-Geun

    2016-06-01

    Although range of motion (ROM) is considered as an important factor for good outcome after total knee arthroplasty (TKA), the association of the degree of ROM with functional outcome and patient satisfaction is debated. We, therefore, investigated whether increased ROM would affect functional outcome and patient satisfaction after TKA in Asian patients. We reviewed 630 patients who underwent primary TKA with minimum 2-year follow-up. Clinical outcomes were evaluated by Knee Society (KS) score, Western Ontario and McMaster Universities osteoarthritis index, and high-flexion knee score. Patient satisfaction was evaluated using a validated questionnaire. The association of ROM and change in ROM (cROM) with clinical outcomes and satisfaction were analyzed using partial correlation analysis and multiple median regression analysis. All functional scores showed significant correlation with postoperative ROM (r = 0.129, P = .001 in Knee Society score; r = -0.101, P = .012 in Western Ontario and McMaster Universities osteoarthritis index; r = 0.183, P satisfaction (r = 0.192, P = .005). Postoperative ROM and cROM were revealed as predisposing factors affecting function outcome using multivariable regression analysis. cROM was found as a predisposing factor affecting satisfaction. Based on the results of this study, ROM positively associated with functional outcome and cROM positively associated with patient satisfaction after TKA. These findings suggest that increased ROM after TKA is an important factor for functional outcome and satisfaction in Asian patients. Copyright © 2015 Elsevier Inc. All rights reserved.

  13. Analysis of changes in the percentage of B (CD19) and T (CD3) lymphocytes, nk cells, subsets CD4, CD8 in differentiated thyroid cancer patients treated with iodine-131

    International Nuclear Information System (INIS)

    Luo Quanyong; Yu Yongli; Chen Libo; Lu Hankui; Zhu Ruisen

    2004-01-01

    reduction in the CD4+/CD8+ ratio at day 30 (P=0.007). At day 90, in all patients there are no significant reduction compared to the baseline in the percentage of B and T lymphocytes, NK cells, subsets CD4, CD8 and CD4+/CD8+ ratios. However, neither group showed any clinical sign of immunosuppression during the follow-up period. Conclusions: In DTC patients, the sensitivity of lymphocytes to the effects of iodine-131 internal radiation largely depends upon lymphocyte phenotype and iodine-131 activity. NK cells and B lymphocytes seem to be the most radiosensitive cells. At higher iodine-131 activity B and T lymphocytes, NK cells, subsets CD4, CD8 are all affected. However, the immunosuppression effects are generally temporary and reversible. (authors)

  14. Automatic oscillator frequency control system

    Science.gov (United States)

    Smith, S. F. (Inventor)

    1985-01-01

    A frequency control system makes an initial correction of the frequency of its own timing circuit after comparison against a frequency of known accuracy and then sequentially checks and corrects the frequencies of several voltage controlled local oscillator circuits. The timing circuit initiates the machine cycles of a central processing unit which applies a frequency index to an input register in a modulo-sum frequency divider stage and enables a multiplexer to clock an accumulator register in the divider stage with a cyclical signal derived from the oscillator circuit being checked. Upon expiration of the interval, the processing unit compares the remainder held as the contents of the accumulator against a stored zero error constant and applies an appropriate correction word to a correction stage to shift the frequency of the oscillator being checked. A signal from the accumulator register may be used to drive a phase plane ROM and, with periodic shifts in the applied frequency index, to provide frequency shift keying of the resultant output signal. Interposition of a phase adder between the accumulator register and phase plane ROM permits phase shift keying of the output signal by periodic variation in the value of a phase index applied to one input of the phase adder.

  15. Proceedings of the 4th European conference on protection against radon at home and at work. Conference programme and session presentations

    International Nuclear Information System (INIS)

    2004-01-01

    The conference was divided into 6 sections as follows (the numbers of PDF files included in the CD-ROM are given in parentheses): 1. Radon measurement in dwellings (7); 2. Radon measurement at workplaces (14); 3. Methods of measurement and devices (16); 4. Remedial measures and techniques (5); 5. Preventive measures and techniques (10); and 6. National radon programmes (6). In addition, the CD-ROM contains 3, 11, 9, 5, 6, and 6 PowerPoint presentations shown in the six sections, respectively, plus a total of 93 abstracts, mostly of posters. (P.A.)

  16. Magnetismo 2000

    Science.gov (United States)

    Cardús, J. O.; Curto, J. J.; Sanclement, E.; Torta, J. M.

    This CD-ROM presents the digital version of the Boletin del Observatorio del Ebro Magnetismo. It contains data obtained in the Magnetic Station of the Ebre Observatory during the year 2000. The structure of the CD-ROM consists of one directory numbered with the year of the measurement. There, it could be found the bulletin as printable sheets (Year.pdf) generate with Adobe Acrobat and data files in plain ASCII text (Year.wdc) readable with any text editor. These data files were compiled according to the data exchange format recommended by the IAGA-2002.

  17. Magnetismo 2002

    Science.gov (United States)

    Cardús, J. O.; Curto, J. J.; Sanclement, E.; Torta, J. M.

    This CD-ROM presents the digital version of the Boletin del Observatorio del Ebro Magnetismo. It contains data obtained in the Magnetic Station of the Ebre Observatory during the year 2002. The structure of the CD-ROM consists of one directory numbered with the year of the measurement. There, it could be found the bulletin as printable sheets (Year.pdf) generate with Adobe Acrobat and data files in plain ASCII text (Year.wdc) readable with any text editor. These data files were compiled according to the data exchange format recommended by the IAGA-2002.

  18. Magnetismo 2003

    Science.gov (United States)

    Cardús, J. O.; Curto, J. J.; Sanclement, E.; Torta, J. M.

    This CD-ROM presents the digital version of the Boletin del Observatorio del Ebro Magnetismo. It contains data obtained in the Magnetic Station of the Ebre Observatory during the year 2003. The structure of the CD-ROM consists of one directory numbered with the year of the measurement. There, it could be found the bulletin as printable sheets (Year.pdf) generate with Adobe Acrobat and data files in plain ASCII text (Year.wdc) readable with any text editor. These data files were compiled according to the data exchange format recommended by the IAGA-2002.

  19. Magnetismo 2001

    Science.gov (United States)

    Cardús, J. O.; Curto, J. J.; Sanclement, E.; Torta, J. M.

    This CD-ROM presents the digital version of the Boletin del Observatorio del Ebro Magnetismo. It contains data obtained in the Magnetic Station of the Ebre Observatory during the year 2001. The structure of the CD-ROM consists of one directory numbered with the year of the measurement. There, it could be found the bulletin as printable sheets (Year.pdf) generate with Adobe Acrobat and data files in plain ASCII text (Year.wdc) readable with any text editor. These data files were compiled according to the data exchange format recommended by the IAGA-2002.

  20. The Effect of Trichoderma harzianum and Cadmium on Tolerance Index and Yield of Barley (Hordeum vulgare L.

    Directory of Open Access Journals (Sweden)

    F. Taghavi Ghasemkheyli

    2015-01-01

    Full Text Available To investigate the effect of Trichoderma harzianum, as a bioabsorbant to ameliorate the harmful effects of cadmium (Cd on growth and yield of barley (Hordeum vulgare L. variety ‘Sahra’, a factorial pot experiment based on completely randomized design with three replicates was conducted. Trichoderma harzianum withtwo levels (with and without inoculation and cadmium nitrate with four levels (0, 50, 100 and 150 mg.L-1 were the treatments. Results of ANOVA revealed that there was a significant interaction between Trichoderma and cadmium nitrate in terms of biological yield, straw yield, harvest index, spike number per plant and seed number per spike. Mean comparisons showed that Trichoderma inoculation at all Cd levels significantly improved both biological and straw yields. Trichoderma at 50 and 100 mg.L-1 of Cd also increased the spike number per plant (up to 120 and 66%, respectively significantly. Increasing Cd levels decreased seed yield (19%, 1000 seed weight (18%, partitioning coefficient (57% and tolerance index (23% significantly. Inoculation of Trichoderma into growth medium had a significant effect on seed yield and tolerance index (up to 17 and 22%, respectively. In conclusion, Trichoderma harzianum inoculation at lower concentrations of Cd (50 and 100 mg.L-1 could be effective to improve growth parameters of barley plant.

  1. [Oxidative damage effects induced by CdTe quantum dots in mice].

    Science.gov (United States)

    Xie, G Y; Chen, W; Wang, Q K; Cheng, X R; Xu, J N; Huang, P L

    2017-07-20

    Objective: To investigate Oxidative damage effects induced by CdTe Quantum Dots (QDs) in mice. Methods: 40 ICR mice were randomly divided into 5 groups: one control group (normal saline) ; four CdTe QDs (exposed by intravenous injection of 0.2 ml of CdTe QDs at the concentration of 0、0.5、5.0、50.0 and 500.0 nmol/ml respectively) . After 24 h, the mice were decapitated and the blood was collected for serum biochemically indexes、hematology indexes, the activities of SOD、GSH-Px and the concentration of MDA were all detected. Results: The results showed in the four CdTe QDs exposure groups, the level of CRE、PLT and the concentration of MDA were all significantly lower than those of the control group ( P control group ( P <0.01) . Conclusion: It was suggested that CdTe QDs at 0.5 nmol/ml could induce Oxidative damage effects in mice.

  2. Dificultăți de traducere în limba română a Aforismelor lui Arthur Schopenhauer. O analiză contrastiv-diacronică (I

    Directory of Open Access Journals (Sweden)

    Cecilia-Iuliana Vârlan

    2016-02-01

    Full Text Available Lucrarea de față se concentrează asupra unei opere de maturitate a filozofului german Arthur Schopenhauer, Aforisme asupra înțelepciunii în viață, și asupra singurei versiuni românești a acesteia, realizate de Titu Maiorescu la sfîrșitul secolului al XIX-lea. Existența a cinci variante ale versiunii românești, publicate de traducătorul însuși de-a lungul a patru decenii, reprezintă o dovadă clară a faptului că transpunerea în românește a acestui text de filozofie practică a incumbat o serie întreagă de dificultăți de traducere. Urmărind modul în care Titu Maiorescu a încercat să rezolve aceste dificultăți, prin adoptarea anumitor soluții traductologice, am realizat o analiză a acestora, din perspectivă lingvistică, cercetarea urmînd concomitent două direcții: contrastivă (rezultată din supra- punerea textului-sursă și a textului-țintă și diacronică (urmărind intervențiile realizate de același traducător asupra propriului text, la intervale de timp diferite. Demersul de analiză lingvistică a traducerii unui text filozofic ni s-a părut util nu doar studiului nostru, ci și viitorilor eventuali traducători ai Aforismelor, a căror intenție ar putea fi aceea de a adapta discursul versiunii românești a lui Titu Maiorescu la limba română contemporană, ținînd seama de evoluția evidentă a acesteia și, mai ales, a componentei sale de limbaj filozofic.

  3. Downregulation of CD44 reduces doxorubicin resistance of CD44+CD24- breast cancer cells

    Directory of Open Access Journals (Sweden)

    Phuc PV

    2011-06-01

    Full Text Available Pham Van Phuc, Phan Lu Chinh Nhan, Truong Hai Nhung, Nguyen Thanh Tam, Nguyen Minh Hoang, Vuong Gia Tue, Duong Thanh Thuy, Phan Kim NgocLaboratory of Stem Cell Research and Application, University of Science, Vietnam National University, Ho Chi Minh, VietnamBackground: Cells within breast cancer stem cell populations have been confirmed to have a CD44+CD24- phenotype. Strong expression of CD44 plays a critical role in numerous types of human cancers. CD44 is involved in cell differentiation, adhesion, and metastasis of cancer cells.Methods: In this study, we reduced CD44 expression in CD44+CD24- breast cancer stem cells and investigated their sensitivity to an antitumor drug. The CD44+CD24- breast cancer stem cells were isolated from breast tumors; CD44 expression was downregulated with siRNAs followed by treatment with different concentrations of the antitumor drug.Results: The proliferation of CD44 downregulated CD44+CD24- breast cancer stem cells was decreased after drug treatment. We noticed treated cells were more sensitive to doxorubicin, even at low doses, compared with the control groups.Conclusions: It would appear that expression of CD44 is integral among the CD44+CD24- cell population. Reducing the expression level of CD44, combined with doxorubicin treatment, yields promising results for eradicating breast cancer stem cells in vitro. This study opens a new direction in treating breast cancer through gene therapy in conjunction with chemotherapy.Keywords: antitumor drugs, breast cancer stem cells, CD44, CD44+CD24- cells, doxorubicin

  4. Percentages of CD4+CD161+ and CD4−CD8−CD161+ T Cells in the Synovial Fluid Are Correlated with Disease Activity in Rheumatoid Arthritis

    Directory of Open Access Journals (Sweden)

    Jinlin Miao

    2015-01-01

    Full Text Available Objective. CD161 has been identified as a marker of human IL-17-producing T cells that are implicated in the pathogenesis of rheumatoid arthritis (RA. This study aimed to investigate the potential link between the percentage of CD161+ T cells and disease activity in RA patients. Methods. Peripheral blood (PB from 54 RA patients and 21 healthy controls was evaluated. Paired synovial fluid (SF (n = 17 was analyzed. CD161 expression levels on CD4+, CD8+, and CD4−CD8− T cells were assessed by flow cytometry. Results. The percentage of CD4+CD161+ T cells in RA SF was higher than RA PB, and it was positively correlated with DAS28, erythrocyte sedimentation rate (ESR, and C-reactive protein (CRP. CD4−CD8−CD161+ T cell percentage was decreased in RA PB and was further reduced in RA SF, and its level in SF was inversely correlated with DAS28, ESR, and CRP. However, CD8+CD161+ T cell percentage was neither changed in RA PB and SF nor correlated with disease activity indices. Conclusion. An increased CD4+CD161+ T cell percentage and a decreased CD4−CD8−CD161+ T cell percentage are present in RA SF and are associated with disease activity, and the accumulation of CD4+CD161+ T cells in SF may contribute to the local inflammation of RA.

  5. Differential number of CD34+, CD133+ and CD34+/CD133+ cells in peripheral blood of patients with congestive heart failure

    Directory of Open Access Journals (Sweden)

    Fritzenwanger M

    2009-03-01

    Full Text Available Abstract Background Endothelial progenitor cells (EPC which are characterised by the simulateous expression of CD34, CD133 and vascular endothelial growth receptor 2 (VEGF 2 are involved in the pathophysiology of congestive heart failure (CHF and their number and function is reduced in CHF. But so far our knowledge about the number of circulating hematopoietic stem/progenitor cells (CPC expressing the early hematopoietic marker CD133 and CD34 in CHF is spares and therefore we determined their number and correlated them with New York Heart Association (NYHA functional class. Methods CD34 and CD133 surface expression was quantified by flow cytometry in the peripheral venous blood of 41 healthy adults and 101 patients with various degrees of CHF. Results CD34+, CD133+ and CD34+/CD133+ cells correlated inversely with age. Both the number of CD34+ and of CD34+/CD133+ cells inversely correlated with NYHA functional class. The number of CD133+ cells was not affected by NYHA class. Furthermore the number of CD133+ cells did not differ between control and CHF patients. Conclusion In CHF the release of CD34+, CD133+ and CD34+/CD133+ cells from the bone marrow seems to be regulated differently. Modulating the releasing process in CHF may be a tool in CHF treatment.

  6. An end-to-end coupled model ROMS-N 2 P 2 Z 2 D 2 -OSMOSE of ...

    African Journals Online (AJOL)

    An end-to-end coupled model ROMS-N 2 P 2 Z 2 D 2 -OSMOSE of the southern Benguela foodweb: parameterisation, calibration and pattern-oriented validation. ... We also highlight the capacity of this model for tracking indicators at various hierarchical levels. Keywords: individual-based model, model validation, ...

  7. A Survey of Recent Advances in Optical and Multimedia Information Technologies.

    Science.gov (United States)

    Jessop, Deborah

    1997-01-01

    Examines developments in multimedia technologies and in the World Wide Web. Discusses CD-recordable, CD-rewritable, cable modems, personal digital assistants, digital video discs, interactivity and virtual worlds, advertising on the Web, and Intranets and CD-ROM networks. Eight tables and figures show costs, download time, estimated sales, storage…

  8. Fabrication and characterization of Ag-Cd/CdO materials produced by incorporation of CdO particles to liquid Ag-Cd alloys; Fabricacion y caracterizacion de materiales Ag-Cd/CdO producidos mediante incorporacion de particulas de CdO en aleaciones Ag-Cd liquidas

    Energy Technology Data Exchange (ETDEWEB)

    Equihua-Guillen, F.; Ruiz-Mondragon, J.; Servin-Castaneda, R.; Orozco-Gonzalez, P.; Zaldivar-Cadena, A.; Martinez-Villafane, F.; Villarreal-Garza, E. J.

    2014-04-01

    In the present work it has been investigated the kinetic behavior of internal oxidation processes of strips of Ag-Cd/CdO materials fabricated by adding CdO particles (size of 5 and 20 {mu}m) in liquid Ag-Cd alloys. It has been established the metallurgical mechanism that controls the formation of the thickness covered with CdO particles produced by internal oxidation of the Ag-Cd/CdO material. It has been developed, successfully, a metallographic preparation technique for characterizing the morphology, size and distribution of CdO particles produced by heat treatment of internal oxidation on the surface of each sample based on the distance from the original surface to the boundary of dispersed CdO particles. The material strips were sequentially roughed on its surface and the roughing thickness was measured in the cross section of each new surface to determine the number of particles per area and average particle size. (Author)

  9. Genome-wide expression profiling analysis to identify key genes in the anti-HIV mechanism of CD4+ and CD8+ T cells.

    Science.gov (United States)

    Gao, Lijie; Wang, Yunqi; Li, Yi; Dong, Ya; Yang, Aimin; Zhang, Jie; Li, Fengying; Zhang, Rongqiang

    2018-07-01

    Comprehensive bioinformatics analyses were performed to explore the key biomarkers in response to HIV infection of CD4 + and CD8 + T cells. The numbers of CD4 + and CD8 + T cells of HIV infected individuals were analyzed and the GEO database (GSE6740) was screened for differentially expressed genes (DEGs) in HIV infected CD4 + and CD8 + T cells. Gene Ontology enrichment, KEGG pathway analyses, and protein-protein interaction (PPI) network were performed to identify the key pathway and core proteins in anti-HIV virus process of CD4 + and CD8 + T cells. Finally, we analyzed the expressions of key proteins in HIV-infected T cells (GSE6740 dataset) and peripheral blood mononuclear cells(PBMCs) (GSE511 dataset). 1) CD4 + T cells counts and ratio of CD4 + /CD8 + T cells decreased while CD8 + T cells counts increased in HIV positive individuals; 2) 517 DEGs were found in HIV infected CD4 + and CD8 + T cells at acute and chronic stage with the criterial of P-value T cells. The main biological processes of the DEGs were response to virus and defense response to virus. At chronic stage, ISG15 protein, in conjunction with IFN-1 pathway might play key roles in anti-HIV responses of CD4 + T cells; and 4) The expression of ISG15 increased in both T cells and PBMCs after HIV infection. Gene expression profile of CD4 + and CD8 + T cells changed significantly in HIV infection, in which ISG15 gene may play a central role in activating the natural antiviral process of immune cells. © 2018 Wiley Periodicals, Inc.

  10. Changes in Reactivity In Vitro of CD4+CD25+ and CD4+CD25− T Cell Subsets in Transplant Tolerance

    Science.gov (United States)

    Hall, Bruce M.; Robinson, Catherine M.; Plain, Karren M.; Verma, Nirupama D.; Tran, Giang T.; Nomura, Masaru; Carter, Nicole; Boyd, Rochelle; Hodgkinson, Suzanne J.

    2017-01-01

    Transplant tolerance induced in adult animals is mediated by alloantigen-specific CD4+CD25+ T cells, yet in many models, proliferation of CD4+ T cells from hosts tolerant to specific-alloantigen in vitro is not impaired. To identify changes that may diagnose tolerance, changes in the patterns of proliferation of CD4+, CD4+CD25+, and CD4+CD25− T cells from DA rats tolerant to Piebald Virol Glaxo rat strain (PVG) cardiac allografts and from naïve DA rats were examined. Proliferation of CD4+ T cells from both naïve and tolerant hosts was similar to both PVG and Lewis stimulator cells. In mixed lymphocyte culture to PVG, proliferation of naïve CD4+CD25− T cells was greater than naïve CD4+ T cells. In contrast, proliferation of CD4+CD25− T cells from tolerant hosts to specific-donor PVG was not greater than CD4+ T cells, whereas their response to Lewis and self-DA was greater than CD4+ T cells. Paradoxically, CD4+CD25+ T cells from tolerant hosts did not proliferate to PVG, but did to Lewis, whereas naïve CD4+CD25+ T cells proliferate to both PVG and Lewis but not to self-DA. CD4+CD25+ T cells from tolerant, but not naïve hosts, expressed receptors for interferon (IFN)-γ and IL-5 and these cytokines promoted their proliferation to specific-alloantigen PVG but not to Lewis or self-DA. We identified several differences in the patterns of proliferation to specific-donor alloantigen between cells from tolerant and naïve hosts. Most relevant is that CD4+CD25+ T cells from tolerant hosts failed to proliferate or suppress to specific donor in the absence of either IFN-γ or IL-5. The proliferation to third-party and self of each cell population from tolerant and naïve hosts was similar and not affected by IFN-γ or IL-5. Our findings suggest CD4+CD25+ T cells that mediate transplant tolerance depend on IFN−γ or IL-5 from alloactivated Th1 and Th2 cells. PMID:28878770

  11. Effector T-cells are expanded in systemic lupus erythematosus patients with high disease activity and damage indexes.

    Science.gov (United States)

    Piantoni, S; Regola, F; Zanola, A; Andreoli, L; Dall'Ara, F; Tincani, A; Airo', P

    2018-01-01

    Background and objectives T-cell activation may be one of the pathogenic mechanisms of systemic lupus erythematosus (SLE). After repeated antigenic stimulation, T-cells undergo different modifications, leading to the differentiation into effector memory T-cells (CCR7-CD45RA-) and terminally differentiated effector memory (TDEM) T-cells (CCR7-CD45RA+). Similarly, down-modulation of CD28 may lead to the expansion of the CD28- T-cells, a subpopulation with peculiar effector activities. The aim of this study was the characterization of T-cell phenotype in a cohort of patients with SLE according to disease activity and damage index. Materials and methods Phenotypic analysis of peripheral blood T lymphocytes of 51 SLE patients and 21 healthy controls was done by flow-cytometry. SLE disease activity was evaluated by SLE Disease Activity Index-2000 (SLEDAI-2K) and damage by the Systemic Lupus International Collaborating Clinics/American College of Rheumatology damage index (SDI). The variations between different groups were evaluated by Mann-Whitney test. Bonferroni correction was applied to adjust for multiple comparisons ( p adj ). Spearman rank test was used to evaluate the correlations between quantitative variables. Results CD4+ lymphopenia was found among SLE patients. Patients showed a trend for a higher percentage of TDEM among the CD4+ T-cell subpopulation in comparison with healthy controls ( p = .04). SLE patients were divided into two groups according to disease activity: patients with SLEDAI-2K ≥ 6 ( n = 13) had a higher percentage of circulating CD4+ T-cells with CD28- phenotype ( p adj  = .005) as well as those with an effector memory ( p adj  = .004) and TDEM ( p adj  = .002) phenotype and a trend of decrease of regulatory T-cells (TREGs) ( p = .02), in comparison with patients with low disease activity ( n = 38). Patients with damage (SDI ≥ 1) tended to show an expansion of TDEM among CD4+ T-cells as compared with

  12. Grafiskā stāstījuma uzbūve un trauma Hāleda Hoseinī grafiskajā romānā “Pūķa ķērājs”

    OpenAIRE

    Vanaga, Alīna

    2016-01-01

    Hāleda Hoseinī grafiskais romāns “Pūķa ķērājs”demonstrē grafisko romānu spēju vienlaicīgi uzrunāt lielu cilvēku daudzumu un tajā pašā laikā izteikt neaprakstāmo, kas apliecina to, ka grafiskie romāni ļoti labi prot darīt saprotamas tādas neaprakstāmas tēmas, kā trauma. Tādēļ, šī maģistra darba mērķis ir noteikt, kā grafiskā stāstījuma uzbūve attēlo traumu Hāleda Hoseinī grafiskajā romāna “Pūķa ķērājs” un kādu rezultātu tas rada. Iepriekš minētā mērķa sasniegšanai tika izvēlētas divas pētīšana...

  13. Evaluation of pretransplant immunologic status in kidney-transplant recipients by panel reactive antibody and soluble CD30 determinations.

    Science.gov (United States)

    Cinti, Paola; Pretagostini, Renzo; Arpino, Alessia; Tamburro, Maria Luisa; Mengasini, Sonia; Lattanzi, Roberto; De Simone, Paolo; Berloco, Pasquale; Molajoni, Elvira Renna

    2005-05-15

    To retrospectively compare the accuracy of pretransplant panel of reactivity antibodies (PRA) and serum level of soluble CD30 (sCD30) in predicting early (acute rejection (AR) in living-donor and deceased-donor kidney-transplant (KT) patients. Pretransplant sera of 24 KT recipients were retrospectively tested for sCD30 and compared with PRA. Inclusion criteria were de novo graft patients on calcineurin-inhibitor-based immunosuppression, minimum follow-up of 1 year, alive with a functioning graft, and stable renal function over the last 12 months. Objective measures were incidence of biopsy-proven AR (BPAR) within 6 months of KT and sCD30 and PRA diagnostic indexes. The relative risk (RR) of BPAR for each test was also obtained. Fourteen (58.3%) patients presented at least one episode of BPAR within 6 months of KT. All rejection episodes were responsive to steroid treatment. PRA was positive in six (25%) patients, and four (66.7%) of them presented at least one episode of BPAR. sCD30 tested positive in nine (37.5%) patients, and all these later presented at least one episode of BPAR. sCD30 and PRA diagnostic indexes in predicting early (sCD30-positive group. Pretransplant sCD30 is a more accurate predictor of AR when compared with PRA. These results support its use in the pretransplant work-up of kidney-graft recipients.

  14. Poemele homerice în veșminte românești. O analiză diacronică (I

    Directory of Open Access Journals (Sweden)

    Petre Gheorghe Bârlea

    2015-07-01

    Full Text Available Lucrarea pe care o propunem vizează istoria traducerilor românești ale poemelor homerice, din perspectiva evoluției limbii române literare. Pornim de la premisa că orice asemenea traducere reprezintă o probă de virtuozitate nu numai pentru traducătorul în cauză, ci și pentru limba și cultura modernă respectivă, așa încît este interesant de studiat modul în care dezvoltarea exegezei homerice și a teoriilor traductologice se manifestă în paralel cu etapele evoluției limbilor moderne. Grila de analiză va include, așadar, principii, metode și instrumente de lucru ale domeniilor amintite aici (istoria limbii, traductologie, dar și elemente împrumutate din gramatica constrastiv-tipologică, din filologie, în sensul restrîns al conceptului, din teoria mentalităților, istoria culturală ș.a. Demersul nostru evidențiază faptul că evoluția istorică a actului traducerii este marcată, în mod firesc, de personalitatea traducătorului (opțiuni teoretice, ideologice, pe lîngă competențe lingvistice, har poetic etc., dar și de contextul cultural al epocii și al spațiului respectiv. Pentru cultura română, cel puțin, putem constata că, în ansamblu, versiunea cea mai recentă este și cea mai reușită.

  15. Uptake pathways and toxicity of Cd and Zn in the earthworm Eisenia fetida.

    NARCIS (Netherlands)

    Li, L.-Z.; Zhou, D.-M.; Peijnenburg, W.J.G.M.; Wang, P.; van Gestel, C.A.M.; Jin, S.-Y.; Wang, Q.-Y.

    2010-01-01

    The uptake of Cd and Zn by the earthworm Eisenia fetida was determined at varying Ca concentrations and with pre-exposure to different metabolic inhibitors in simulated soil solutions over a 48-h period. The presence of Ca in the solution had complex actions on Cd uptake. At a low Cd concentration

  16. Changes and clinical significance of CD4+CD25+CD127- regulatory T cells in Graves disease

    International Nuclear Information System (INIS)

    Zou Jintao; Yu Peiling; Dong Jingwei; Liao Qihong; Liu Dongliang; Zeng Hongyi

    2012-01-01

    Objective: To investigate the mechanism of Graves disease by observing the changes of CD4 + CD25 + CD127 - regulatory T cells (Treg) population in the patients. Methods: Flow cytometry was used to detect the proportion of CD4 + CD25 + CD127 - Treg of CD4 + T cells in 90 Graves disease patients (Graves disease group) and 50 healthy adults (control group). Thyroid function and autoantibody levels were determined simultaneously. The t test was adopted for comparison between groups. The relationship between CD4 + CD25 + CD127 - Treg and thyroid function was analyzed by linear correlation analysis. Results: The percentages of CD4 + CD25 + CD127 - Treg in Graves disease group and control group were 1.39%±1.09% and 4.59%±1.14% separately. There was significant difference between the two groups (t=16.4, P<0.01). There were negative correlation between CD4 + CD25 + CD127 - Treg percentages and total triiodothyronine, total thyroxine,free triiodothyronine, free thyroxine and thyrotropin receptor antibody,thyroglobulin antibody, thyroid microsomal antibody (r=-0.62, -0.65, -0.56, -0.71, -0.50, -0.15, all P<0.01). Conclusions: The reduction of CD4 + CD25 + CD127 - Treg percentages in Graves disease group and close relations of CD4 + CD25 + CD127 - Treg with thyroid function and thyroid autoantibody levels suggest that CD4 + CD25 + CD127 - Treg decrease in the number may be associated with the onset of Graves disease. CD4 + CD25 + CD127 - may be the specific marker of Treg. (authors)

  17. Validation of the All Patient Refined Diagnosis Related Group (APR-DRG) Risk of Mortality and Severity of Illness Modifiers as a Measure of Perioperative Risk.

    Science.gov (United States)

    McCormick, Patrick J; Lin, Hung-Mo; Deiner, Stacie G; Levin, Matthew A

    2018-03-22

    The All Patient Refined Diagnosis Related Group (APR-DRG) is an inpatient visit classification system that assigns a diagnostic related group, a Risk of Mortality (ROM) subclass and a Severity of Illness (SOI) subclass. While extensively used for cost adjustment, no study has compared the APR-DRG subclass modifiers to the popular Charlson Comorbidity Index as a measure of comorbidity severity in models for perioperative in-hospital mortality. In this study we attempt to validate the use of these subclasses to predict mortality in a cohort of surgical patients. We analyzed all adult (age over 18 years) inpatient non-cardiac surgery at our institution between December 2005 and July 2013. After exclusions, we split the cohort into training and validation sets. We created prediction models of inpatient mortality using the Charlson Comorbidity Index, ROM only, SOI only, and ROM with SOI. Models were compared by receiver-operator characteristic (ROC) curve, area under the ROC curve (AUC), and Brier score. After exclusions, we analyzed 63,681 patient-visits. Overall in-hospital mortality was 1.3%. The median number of ICD-9-CM diagnosis codes was 6 (Q1-Q3 4-10). The median Charlson Comorbidity Index was 0 (Q1-Q3 0-2). When the model was applied to the validation set, the c-statistic for Charlson was 0.865, c-statistic for ROM was 0.975, and for ROM and SOI combined the c-statistic was 0.977. The scaled Brier score for Charlson was 0.044, Brier for ROM only was 0.230, and Brier for ROM and SOI was 0.257. The APR-DRG ROM or SOI subclasses are better predictors than the Charlson Comorbidity Index of in-hospital mortality among surgical patients.

  18. CD3 Positive Gastric Plasmablastic Lymphoma in A HIV Negative Patient: A Case Report

    Directory of Open Access Journals (Sweden)

    Betül Bolat Küçükzeybek,

    2017-03-01

    Full Text Available Plasmablastic lymphoma is a rare and aggressive lymphoma characterized by the diffuse proliferation of large neoplastic cells resembling immunoblasts with an immunophenotype of plasma cells. A 47-year-old male was referred to our hospital with gastrointestinal bleeding, and a mass 10 cm in diameter, was detected. An endoscopic biopsy was performed subsequently. Histopathological examination of the biopsy material revealed ulcer, alterations associated with ulcer, and further presented a diffuse infiltration of atypical cells with abundant cytoplasm and pleomorphic nuclei, some with crush artifacts in lamina propria. Immunohistochemically, the tumor cells were negative for cytokeratin, CD2, CD20, and PAX5; but they were positive for CD3, MUM1, CD38 and CD138. Ki67 proliferation index was as high as 95%. The case was signed out as CD3-positive plasmablastic lymphoma with clinical, histopathological and immunohisto-chemical findings. The plasmablastic lymphoma case with an aberrant CD3 expression has been presented here, which is rarely observed in stomach.

  19. Phenotyping and Target Expression Profiling of CD34+/CD38− and CD34+/CD38+ Stem- and Progenitor cells in Acute Lymphoblastic Leukemia

    Directory of Open Access Journals (Sweden)

    Katharina Blatt

    2018-06-01

    Full Text Available Leukemic stem cells (LSCs are an emerging target of curative anti-leukemia therapy. In acute lymphoblastic leukemia (ALL, LSCs frequently express CD34 and often lack CD38. However, little is known about markers and targets expressed in ALL LSCs. We have examined marker- and target expression profiles in CD34+/CD38− LSCs in patients with Ph+ ALL (n = 22 and Ph− ALL (n = 27 by multi-color flow cytometry and qPCR. ALL LSCs expressed CD19 (B4, CD44 (Pgp-1, CD123 (IL-3RA, and CD184 (CXCR4 in all patients tested. Moreover, in various subgroups of patients, LSCs also displayed CD20 (MS4A1 (10/41 = 24%, CD22 (12/20 = 60%, CD33 (Siglec-3 (20/48 = 42%, CD52 (CAMPATH-1 (17/40 = 43%, IL-1RAP (13/29 = 45%, and/or CD135 (FLT3 (4/20 = 20%. CD25 (IL-2RA and CD26 (DPPIV were expressed on LSCs in Ph+ ALL exhibiting BCR/ABL1p210, whereas in Ph+ ALL with BCR/ABL1p190, LSCs variably expressed CD25 but did not express CD26. In Ph− ALL, CD34+/CD38− LSCs expressed IL-1RAP in 6/18 patients (33%, but did not express CD25 or CD26. Normal stem cells stained negative for CD25, CD26 and IL-1RAP, and expressed only low amounts of CD52. In xenotransplantation experiments, CD34+/CD38− and CD34+/CD38+ cells engrafted NSG mice after 12–20 weeks, and targeting with antibodies against CD33 and CD52 resulted in reduced engraftment. Together, LSCs in Ph+ and Ph− ALL display unique marker- and target expression profiles. In Ph+ ALL with BCR/ABL1p210, the LSC-phenotype closely resembles the marker-profile of CD34+/CD38− LSCs in chronic myeloid leukemia, confirming the close biologic relationship of these neoplasms. Targeting of LSCs with specific antibodies or related immunotherapies may facilitate LSC eradication in ALL.

  20. The impact of multimedia on teaching tropical medicine

    Directory of Open Access Journals (Sweden)

    M. F. Sarmento e Souza

    2004-01-01

    Full Text Available This study evaluated the impact of multimedia in the information transfer of subjects specific to Tropical Diseases - Tetanus and Snake Envenoming. We evaluated the autonomous learning process of 76 fourth-year medical students at Botucatu School of Medicine of UNESP, using printed matter, video, and CD-ROM. The students were submitted to a specific test, which was repeated approximately one week later. They were divided into groups and received a kit containing a textbook, a video, and a CD-ROM. These materials were used for out-of-class study. Before the second test, the students gave a seminar,where they discussed and resolved their doubts with their professor. The results of the first test showed averagesbetween 4.27±1.41 and 6.41±1.61. The second test, given after the seminar, presented averages that increased to 8.41±0.76 and 9.52±0.42, significance a = 5%. At the end of the course, the students answered a questionnaire, which evaluated the material quality and acquired knowledge. The students concluded that multimedia was a more efficient and quick means for knowledge building than traditional teaching materials. They said that the active participation and interactivity with the CD-ROM were the major differences. The authors continue to study the associated use of printed matter, video, and CD-ROM as a faster alternative to the traditional method of information transfer, which may be of help in the knowledge building process in medical education.

  1. THE EFFECT OF INTELLECTUAL CAPITAL AND ISLAMICITY PERFORMANCE INDEX TO THE PERFORMANCE OF ISLAMIC BANK IN INDONESIA 2010-2014 PERIODS

    Directory of Open Access Journals (Sweden)

    Pandu Dewanata

    2016-09-01

    Full Text Available The purpose of this research is to know the influence of intellectual capital and islamicity performance index by proxy is profit-sharing ratio, zakat performance ratio, and equitable distribution ratio on performance of Islamic bank in Indonesia in the period 2010-2014. The data used in this research is financial statement of 11 Islamic bank in Indonesia 2010-2014 periods. Regression model using panel data with Fixed Effect Model. The result of this research is intellectual capital and zakat performance ratio has significant and positif impact on ROA, while equitable distribution ratio has not significant impact on ROA, and profit sharing ratio has significant and positif impact on ROA.

  2. MCT4 surpasses the prognostic relevance of the ancillary protein CD147 in clear cell renal cell carcinoma.

    Science.gov (United States)

    Fisel, Pascale; Stühler, Viktoria; Bedke, Jens; Winter, Stefan; Rausch, Steffen; Hennenlotter, Jörg; Nies, Anne T; Stenzl, Arnulf; Scharpf, Marcus; Fend, Falko; Kruck, Stephan; Schwab, Matthias; Schaeffeler, Elke

    2015-10-13

    Cluster of differentiation 147 (CD147/BSG) is a transmembrane glycoprotein mediating oncogenic processes partly through its role as binding partner for monocarboxylate transporter MCT4/SLC16A3. As demonstrated for MCT4, CD147 is proposed to be associated with progression in clear cell renal cell carcinoma (ccRCC). In this study, we evaluated the prognostic relevance of CD147 in comparison to MCT4/SLC16A3 expression and DNA methylation. CD147 protein expression was assessed in two independent ccRCC-cohorts (n = 186, n = 59) by immunohistochemical staining of tissue microarrays and subsequent manual as well as automated software-supported scoring (Tissue Studio, Definien sAG). Epigenetic regulation of CD147 was investigated using RNAseq and DNA methylation data of The Cancer Genome Atlas. These results were validated in our cohort. Relevance of prognostic models for cancer-specific survival, comprising CD147 and MCT4 expression or SLC16A3 DNA methylation, was compared using chi-square statistics. CD147 protein expression generated with Tissue Studio correlated significantly with those from manual scoring (P CD147 in ccRCC. Association of CD147 expression with patient outcome differed between cohorts. DNA methylation in the CD147/BSG promoter was not associated with expression. Comparison of prognostic relevance of CD147/BSG and MCT4/SLC16A3, showed higher significance for MCT4 expression and superior prognostic power for DNA methylation at specific CpG-sites in the SLC16A3 promoter (e.g. CD147 protein: P = 0.7780,Harrell's c-index = 53.7% vs. DNA methylation: P = 0.0076, Harrell's c-index = 80.0%). Prognostic significance of CD147 protein expression could not surpass that of MCT4, especially of SLC16A3 DNA methylation, corroborating the role of MCT4 as prognostic biomarker for ccRCC.

  3. Impacts of rapeseed dregs on Cd availability in contaminated acid soil and Cd translocation and accumulation in rice plants.

    Science.gov (United States)

    Yang, Wen-Tao; Gu, Jiao-Feng; Zou, Jia-Ling; Zhou, Hang; Zeng, Qing-Ru; Liao, Bo-Han

    2016-10-01

    The objective of the present study was to investigate the effects of rapeseed dregs (RSD, a commonly organic fertilizer in rural China) at application rates of 0, 0.75, 1.5, and 3.0 % on Cd availability in soil and its accumulation in rice plants (Oryza sativa L., Xiangwanxian 12 # , and Weiyou 46 # ) by means of a pot experiment. The results showed that application of RSD resulted in a sharp decrease in the soil TCLP-extractable Cd content. However, the soil TCLP-extractable Cd content in amended soil gradually increased during the rice growing period. Application of RSD significantly increased Cd transport from root to shoot and the amount of Cd accumulated in the aerial part. RSD was an effective organic additive for increasing rice grain yield, but total Cd content in rice grain was also increased. At an application rate of 1.5-3.0 % RSD, the total Cd content in Weiyou 46 # brown rice was 0.27-0.31 mg kg -1 , which exceeded the standard safe limit (0.2 mg kg -1 ) and was also higher than that of Xiangwanxian 12 # (0.04-0.14 mg kg -1 ). Therefore, Weiyou 46 # had a higher dietary risk than Xiangwanxian 12 # with RSD application. We do not recommend planting Weiyou 46 # and applying more than 0.75 % RSD in Cd-contaminated paddy fields.

  4. CD3+CD8+CD161high Tc17 cells are depleted in HIV-infection

    DEFF Research Database (Denmark)

    Gaardbo, Julie Christine; Hartling, Hans Jakob; Thorsteinsson, Kristina

    2012-01-01

    CD8+ Tc17 cells with pro-inflammatory properties have only recently been acknowledged, and Tc17 cells in HIV-infection are undescribed. CD3+CD8+CD161 Tc17 cells and the production of Interleukin-17 were examined in untreated and treated HIV-infected patients, HIV-HCV co-infected patients...... and healthy controls. Depletion of CD3+CD8+CD161 Tc17 cells and diminished production of Interleukin-17 in HIV-infected patients was found. The level of Tc17 cells was associated with the level of the CD4+ count in treated patients....

  5. EMMPRIN/CD147 is an independent prognostic biomarker in cutaneous melanoma.

    Science.gov (United States)

    Caudron, Anne; Battistella, Maxime; Feugeas, Jean-Paul; Pages, Cécile; Basset-Seguin, Nicole; Mazouz Dorval, Sarra; Funck Brentano, Elisa; Sadoux, Aurélie; Podgorniak, Marie-Pierre; Menashi, Suzanne; Janin, Anne; Lebbé, Céleste; Mourah, Samia

    2016-08-01

    CD147 has been implicated in melanoma invasion and metastasis mainly through increasing metalloproteinase synthesis and regulating VEGF/VEGFR signalling. In this study, the prognostic value of CD147 expression was investigated in a cohort of 196 cutaneous melanomas including 136 consecutive primary malignant melanomas, 30 lymph nodes, 16 in-transit and 14 visceral metastases. A series of 10 normal skin, 10 blue nevi and 10 dermal nevi was used as control. CD147 expression was assessed by immunohistochemistry, and the association of its expression with the clinicopathological characteristics of patients and survival was evaluated using univariate and multivariate statistical analyses. Univariate analysis showed that high CD147 expression was significantly associated with metastatic potential and with a reduced overall survival (P CD147 expression level was correlated with histological factors which were associated with prognosis: Clark level, ulceration status and more particularly with Breslow index (r = 0.7, P CD147 expression level and ulceration status as predicting factors for metastasis and overall survival (P CD147 emerges as an important factor in the aggressive behaviour of melanoma and deserves further evaluation as an independent prognostic biomarker. © 2016 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  6. The Bibliography of Articles of the Republican Era 1923-1999: A Critical Review

    Directory of Open Access Journals (Sweden)

    Yaşar Tonta

    2013-11-01

    Full Text Available The Turkish National Library has recently published the Bibliography of Articles of the Republican Era 1923-1999 (BARE on CD-ROM. BARE is the most comprehensive bibliography that indexes the articles contained in Turkish journals received by the Library through “legal depot”. It contains bibliographic information on a total of566,627 articles that appeared in 4,418 Turkish journals andperiodicals. This paper critically reviews the Bibliography on the basis of its user interface, database design and data quality. Human-computer interaction (HCI issues and the usability criteria seem to have not been taken into account when designing the user interface of the BARE CD-ROM. The user interface is not intuitive. It appears that a comprehensive systems analysis study was not carried out before designing the database and the principles of database management design seem to have been ignored. Bibliographic data listed in the printed copies of the Bibliography was simply transferred to a flat table, which resulted in data redundancy and waste of space. Boolean searches cannot be performed on author and article titles. Nine percent of the records contained errors in article and journal titles as well as authors’ names. Used through the web site of the Turkish National Library, the Bibliography and its interface should be redesigned and improved, and the functions of the search engine should be increased.

  7. Medical radiation physics training EMERALD

    International Nuclear Information System (INIS)

    Tabakov, S.; Roberts, C.; Lamm, I.L.; Milano, F.; Lewis, C.; Smith, D.; Litchev, A.; Jonsson, B.A.; Ljungberg, M.; Strand, S.E.; Jonsson, L.; Riccardi, L.; Benini, A.; Silva, G. da; Teixeira, N.; Pascoal, A.; Noel, A.; Smith, P.; Musilek, L.; Sheahan, N.

    2001-01-01

    Training of young medical physicists is an essential part of the framework of measures for Radiological Protection of Patients. The paper describes the Medical Radiation Physics Training Scheme EMERALD, developed by an European Project Consortium. EMERALD Training covers the Physics of X-ray Diagnostic Radiology, Nuclear Medicine and Radiotherapy. Each of these 3 modules covers 4 months training period. The EMERALD training materials are 3 Workbooks with tasks and a Teachers' Guide (total volume approx 700 pages) and 3 CD-ROMs with image database. (author)

  8. Refractive index and temperature sensors based on no-core fiber cascaded with long period fiber grating

    Science.gov (United States)

    Zhang, Jianming; Pu, Shengli; Rao, Jie; Yao, Tianjun

    2018-05-01

    A kind of compact fibre-optic sensor based on no-core fibre (NCF) cascaded with a strong coupling long-period fibre grating (LPFG) is proposed and experimentally demonstrated. The sensing mechanism is based on the Mach-Zehnder-like interference between the core fundamental mode and cladding mode of the fibre structure. The NCF and LPFG are used as the mode exciter and combiner, respectively. Due to the particular properties of the strong coupling LPFG, the measurements of refractive index (RI) and temperature with high sensitivity are realized by monitoring the transmission spectrum with intensity and wavelength interrogation techniques, respectively. The achieved RI sensitivity reaches -580.269 dB/RIU in the range of 1.436-1.454 and the temperature sensitivity reaches 27.2 pm/°C.

  9. MEDALIST: Communication Drills for Distributed Coaching (CD-ROM)

    National Research Council Canada - National Science Library

    Graves, Christopher R; Jenkins, Samuel N; Flynn, Michael R; Shadrick, Scott B

    2005-01-01

    .... The MEDALIST approach comprises a notional structure of communication drills with varying difficulty levels and scenario settings, targeted training audiences, a distributed performance coaching...

  10. Commercialization of Navy Advanced Wood Composites (CD-ROM)

    National Research Council Canada - National Science Library

    2005-01-01

    .... This work also demonstrated their useful application in marine structures. These research products solve many problems that the US Navy currently face with repairing and building timber structures on their waterfront...

  11. Book Reviews in Periodicals.

    Science.gov (United States)

    Ettelt, Harold J.

    All recent issues of periodicals found which contain indexed book reviews are listed in this compilation from Drake Memorial Library at the New York State University at Brockport. The periodicals are listed by 29 subject headings in this informal guide designed to be used at Drake Library. The number of reviews in the periodical in a recent year…

  12. Peripheral Blood CD64 Levels Decrease in Crohn’s Disease following Granulocyte and Monocyte Adsorptive Apheresis

    Directory of Open Access Journals (Sweden)

    Toshimi Chiba

    2011-12-01

    Full Text Available Granulocyte and monocyte adsorptive apheresis (GMA is reportedly useful as induction therapy for Crohn’s disease (CD. However, the effects of GMA on CD64 have not been well characterized. We report here our assessment of CD64 expression on neutrophils before and after treatment with GMA in two patients with CD. The severity of CD was assessed with the CD activity index (CDAI. The duration of each GMA session was 60 min at a flow rate of 30 ml/min as per protocol. CD64 expression on neutrophils was measured by analyzing whole blood with a FACScan flow cytometer. In case 1, CD64 levels after each session of GMA tended to decrease compared to pretreatment levels, whereas in case 2, CD64 levels dropped significantly after treatment. The CDAI decreased after GMA in both cases 1 and 2. A significant correlation was noted between CDAI scores and CD64 levels in both cases. In conclusion, GMA reduced blood CD64 levels, which would be an important factor for the decrease of CDAI scores.

  13. Relative frequency of immature CD34+/CD90+ subset in peripheral blood following mobilization correlates closely and inversely with the absolute count of harvested stem cells in multiple myeloma patients

    Directory of Open Access Journals (Sweden)

    Balint Bela

    2017-01-01

    Full Text Available Background/Aim. Stem cells (SCs guarantee complete/longterm bone marrow (BM repopulation after SC-transplants. The aim of the study was to evaluate absolute count of total SCs (determined by ISHAGE-sequential-gating protocol – SCish and relative frequency of immature CD34+/CD90+ (CD90+SCish subset in peripheral blood (PB as predictive factors of mobilization and apheresis product (AP quality. Methods. Mobilization included chemotherapy and granulocytegrowth- factor (G-CSF. Harvesting was performed by Spectra- Optia-IDL-system. The SCsish were determined as a constitutional part of CD34+ cells in the “stem-cell-region” using FC- 500 flow-cytometer. In this study, the original ISHAGEsequential- gating protocol was modified by introduction of anti-CD90-PE monoclonal-antibody into the analysis of CD90 expression on SCish (CD90+SCish. The results were presented as a percentage of SCish per nucleated-cell count, absolute SCish count in μL of the PB or the AP, percentage of the CD90+SCish expressed to SCish and absolute CD90+SCish count in μL of the PB or the AP. Results. The absolute count of total SCish and CD90+SCish was significantly higher (p = 0.0007 and p = 0.0266, respectively in the AP than in the PB samples. The CD90+SCish/total SCish indexes from PB were higher than indexes from the AP (p = 0.039. The relative frequency of CD90+SCish showed a highly significant inverse correlation with the absolute count of total SCish in both, the PB and AP (p = 0.0003 and p = 0.0013 respectively. The relative frequency of CD90+SCish from the PB also showed a significant (p = 0.0002 inverse relationship with total SCish count in the AP. Patients with less than 10% CD90+SCish in the PB had evidently higher (p = 0.0025 total SCish count in the AP. Conclusion. We speculate that lower CD90+SCish yield in the AP is not a consequence of an inferior collection efficacy, but most likely a result of several still not fully resolved immature SC

  14. Photonuclear data index 1986-1990

    Energy Technology Data Exchange (ETDEWEB)

    Varlamov, V A; Stepanov, M E; Sapunenko, V V [Moscow State University, Institute of Nuclear Physics, Centre for Photonuclear Experimental Data, Moscow (Russian Federation)

    1992-07-01

    This issue presents a bibliographic index to experimental photonuclear data published in periodical scientific literature during the years 1986-1990. The main tabulation is sorted by nucleus and reaction. It is supplemented by a reference index, an author index, explanatory tables of terms and abbreviations used, and a table of isotopic abundances and nucleon separation energies. The index is in English with an introduction in Russian and English. (author)

  15. Testing an mHealth momentary assessment Routine Outcome Monitoring application: a focus on restoration of daily life positive mood states.

    Directory of Open Access Journals (Sweden)

    Jim van Os

    Full Text Available Routine Outcome Monitoring (ROM is used as a means to enrich the process of treatment with feedback on patient outcomes, facilitating patient involvement and shared decision making. While traditional ROM measures focus on retrospective accounts of symptoms, novel mHealth technology makes it possible to collect real life, in-the-moment ambulatory data that allow for an ecologically valid assessment of personalized and contextualized emotional and behavioural adjustment in the flow daily life (mROM.In a sample of 34 patients with major depressive disorder, treated with antidepressants, the combined effect of treatment and natural course was examined over a period of 18 weeks with Ecological Momentary Assessment (EMA. EMA consisted of repeated, within-subject, mini-measurements of experience (eg positive affect, negative affect, medication side effects and context (eg stressors, situations, activities at 10 unselected semi-random moments per day, for a period of six days, repeated three times over the 18-week period (baseline, week 6 and week 18.EMA measures of emotional and behavioural adjustment were sensitive to the effects of treatment and natural course over the 18-week period, particularly EMA measures focussing on positive mood states and the ability to use natural rewards (impact of positive events on positive mood states, with standardized effect sizes of 0.4-0.5. EMA measures of activities, social interaction, stress-sensitivity and negative mood states were also sensitive to change over time.This study supports the use of mROM as a means to involve the patient in the process of needs assessment and treatment. EMA data are meaningful to the patient, as they reflect daily life circumstances. Assessment of treatment response with mROM data allows for an interpretation of the effect of treatment at the level of daily life emotional and social adjustment--as an index of health, obviating the need for an exclusive focus on traditional measures

  16. Impact of nurse-delivered community-based CD4 services on facilitating pre-ART care in rural South Africa.

    Science.gov (United States)

    Kompala, T; Moll, A P; Mtungwa, N; Brooks, R P; Friedland, G H; Shenoi, S V

    2016-08-11

    HIV testing, diagnosis and treatment programs have expanded globally, particularly in resource-limited settings. Diagnosis must be followed by determination of treatment eligibility and referral to care prior to initiation of antiretroviral treatment (ART). However, barriers and delays along these early steps in the treatment cascade may impede successful ART initiation. New strategies are needed to facilitate the treatment cascade. We evaluated the role of on site CD4+ T cell count phlebotomy services by nurses in facilitating pre-ART care in a community-based voluntary counseling and testing program (CBVCT) in rural South Africa. We retrospectively evaluated CBVCT services during five continuous time periods over three years: three periods when a nurse was present on site, and two periods when the nurse was absent. When a nurse was present, CD4 count phlebotomy was performed immediately after HIV testing to determine ART eligibility. When a nurse was absent, patients were referred to their local primary care clinic for CD4 testing. For each period, we determined the proportion of HIV-positive community members who completed CD4 testing, received notification of CD4 count results, as well as the time to test completion and result notification. Between 2010 and 2013, 7213 individuals accessed CBVCT services; of these, 620 (8.6 %) individuals were HIV-positive, 205 (33.1 %) were eligible for ART according to South African national CD4 count criteria, and 78 (38.0 % of those eligible) initiated ART. During the periods when a professional nurse was available to provide CD4 phlebotomy services, HIV-positive clients were significantly more likely to complete CD4 testing than during periods when these services were not available (85.5 % vs. 37.3 %, p ART care cascade and facilitate timely entry into HIV care.

  17. Antiplaque and antigingivitis effects of a gel containing Punica granatum Linn extract: a double-blind clinical study in humans Efeito antiplaca e antiinflamatório de um gel contendo extrato de romã: estudo clínico duplo-cego em humanos

    Directory of Open Access Journals (Sweden)

    Alexandre Daher Yunes Salgado

    2006-06-01

    Full Text Available OBJECTIVES: The antiplaque and antigingivitis effects of a gel containing 10% Punica granatum Linn extract were evaluated using a 21-day partial-mouth experimental model of gingivitis. METHODS: 23 volunteers participated in this cross-over, double-blind study, carried out in 2 phases of 21 days each. For each period of the experiment, an acrylic toothshield was made for each volunteer to carry the test or placebo gel as well as to avoid brushing of the 4 experimental teeth (posterior teeth in the lower left quadrant. The subjects were randomly assigned to use either the placebo gel (control group or the test gel (experimental group and were instructed to brush the remaining teeth normally 3 times a day. On days 0 and 21, the visible plaque index (VPI and gingival bleeding index (GBI were recorded. RESULTS: The results did not show statistically significant difference between control and experimental groups for either of the indices (VPI and GBI. CONCLUSION: The gel containing 10% Punica granatum Linn extract was not efficient in preventing supragingival dental plaque formation and gingivitis.OBJETIVOS: O efeito antiplaca e antigengivite de um gel contendo extrato de romã a 10% foi avaliado utilizando um modelo de gengivite experimental parcial em humanos. MÉTODOS: 23 indivíduos participaram voluntariamente deste estudo cruzado, duplo-cego, compreendendo dois períodos de 21 dias cada um. Uma moldeira de acrílico foi confeccionada para cada participante, a qual foi utilizada como carreadora dos géis sobre a área a ser avaliada (hemiarco inferior esquerdo. Os sujeitos foram aleatoriamente designados para usar o gel placebo (grupo controle ou o gel teste (grupo experimental, sendo instruídos a colocar o gel na moldeira e esta sobre os dentes teste, escovando os outros normalmente três vezes ao dia. No dia 0 e dia 21 os índices de placa visível (IPV e índice de sangramento gengival (ISG foram registrados. RESULTADOS: Os resultados n

  18. Proceedings of a workshop on dealing with uncertainties in the hydroelectric energy business. CD-ROM ed.

    International Nuclear Information System (INIS)

    2004-01-01

    This workshop was attended by experts in Canadian and international hydroelectric utilities to exchange information on current practices and opportunities for improvement or future cooperation. The discussions focused on reducing the uncertainties associated with hydroelectric power production. Although significant improvements have been made in the efficiency, reliability and safety of hydroelectric power production, the sector is still challenged by the uncertainty of water supply which depends greatly on weather conditions. Energy markets pose another challenge to power producers in terms of energy supply, energy demand and energy prices. The workshop focused on 3 themes: (1) weather and hydrologic uncertainty, (2) market uncertainty, and (3) decision making models using uncertainty principles surrounding water resource planning and operation. The workshop featured 22 presentations of which 11 have been indexed separately for inclusion in this database. refs., tabs., figs

  19. The elastic constants and anisotropy of superconducting MgCNi3 and CdCNi3 under different pressure

    KAUST Repository

    Feng, Huifang

    2013-11-23

    The second-order elastic constants (SOECs) and third-order elastic constants (TOECs) of MgCNi3 and CdCNi3 are presented by using first-principles methods combined with homogeneous deformation theory. The Voigt-Reuss-Hill (VRH) approximation are used to calculate the bulk modulus B, shear modulus G, averaged Young\\'s modulus E and Poisson\\'s ratio ν for polycrystals and these effective modulus are consistent with the experiments. The SOECs under different pressure of MgCNi3 and CdCNi3 are also obtained based on the TOECs. Furthermore, the Zener anisotropy factor, Chung-Buessem anisotropy index, and the universal anisotropy index are used to describe the anisotropy of MgCNi3 and CdCNi3. The anisotropy of Young\\'s modulus of single-crystal under different pressure is also presented. © 2013 Springer Science+Business Media New York.

  20. Synthesis of Monodisperse CdSe QDs using Controlled Growth Temperatures

    International Nuclear Information System (INIS)

    Noor Razinah Rahmat; Akrajas Ali Umar; Muhammad Yahya; Muhamad Mat Salleh; Mohammad Hafizuddin Jumali

    2011-01-01

    The effect of growth temperatures on size of CdSe quantum dots (QDs) has been investigated. CdSe QDs were synthesized using thermolysis of organometallics precursor route using wet chemical method. The growth temperature was varied from 260-310 degree Celsius with growth period fixed at 60 s. As the growth temperature increased, the monodispersed CdSe QDs with diameter in the range 3-7 nm were obtained. Both absorption and PL spectra of the QDs revealed a strong red-shift supporting the increment size of QDs with the rise of growth temperature. (author)

  1. Long-term Mortality in HIV-Positive Individuals Virally Suppressed for >3 Years With Incomplete CD4 Recovery

    DEFF Research Database (Denmark)

    Engsig, Frederik N; Zangerle, Robert; Katsarou, Olga

    2014-01-01

    BACKGROUND: Some human immunodeficiency virus (HIV)-infected individuals initiating combination antiretroviral therapy (cART) with low CD4 counts achieve viral suppression but not CD4 cell recovery. We aimed to identify (1) risk factors for failure to achieve CD4 count >200 cells/µL after 3 years...... of the suppressed period. Logistic regression was used to identify risk factors for incomplete CD4 recovery (≤200 cells/µL) and Cox regression to identify associations with mortality. RESULTS: Of 5550 eligible individuals, 835 (15%) did not reach a CD4 count >200 cells/µL after 3 years of suppression. Increasing...... age, lower initial CD4 count, male heterosexual and injection drug use transmission, cART initiation after 1998, and longer time from initiation of cART to start of the virally suppressed period were risk factors for not achieving a CD4 count >200 cells/µL. Individuals with CD4 ≤200 cells/µL after 3...

  2. Critical role for thymic CD19+CD5+CD1dhiIL-10+ regulatory B cells in immune homeostasis.

    Science.gov (United States)

    Xing, Chen; Ma, Ning; Xiao, He; Wang, Xiaoqian; Zheng, Mingke; Han, Gencheng; Chen, Guojiang; Hou, Chunmei; Shen, Beifen; Li, Yan; Wang, Renxi

    2015-03-01

    This study tested the hypothesis that besides the spleen, LNs, peripheral blood, and thymus contain a regulatory IL-10-producing CD19(+)CD5(+)CD1d(high) B cell subset that may play a critical role in the maintenance of immune homeostasis. Indeed, this population was identified in the murine thymus, and furthermore, when cocultured with CD4(+) T cells, this population of B cells supported the maintenance of CD4(+)Foxp3(+) Tregs in vitro, in part, via the CD5-CD72 interaction. Mice homozygous for Cd19(Cre) (CD19(-/-)) express B cells with impaired signaling and humoral responses. Strikingly, CD19(-/-) mice produce fewer CD4(+)Foxp3(+) Tregs and a greater percentage of CD4(+)CD8(-) and CD4(-)CD8(+) T cells. Consistent with these results, transfer of thymic CD19(+)CD5(+)CD1d(hi) B cells into CD19(-/-) mice resulted in significantly up-regulated numbers of CD4(+)Foxp3(+) Tregs with a concomitant reduction in CD4(+)CD8(-) and CD4(-)CD8(+) T cell populations in the thymus, spleen, and LNs but not in the BM of recipient mice. In addition, thymic CD19(+)CD5(+)CD1d(hi) B cells significantly suppressed autoimmune responses in lupus-like mice via up-regulation of CD4(+)Foxp3(+) Tregs and IL-10-producing Bregs. This study suggests that thymic CD19(+)CD5(+)CD1d(hi)IL-10(+) Bregs play a critical role in the maintenance of immune homeostasis. © Society for Leukocyte Biology.

  3. A multimedia case based approach to the study of office ergonomics.

    Science.gov (United States)

    August-Dalfen, Sharon; Snider, Laurie

    2003-01-01

    Multimedia technology has the capacity to provide students with an interactive approach to problem based learning and to bridge the gap between theoretical knowledge and clinical practice. The present paper describes the design and development of the program ErgoROM, a CD which presents a case study to assist occupational therapy students in their studies of office ergonomics. A pilot study showed that overall, 91% of respondents rated the ErgoROM as either "Excellent" or "Very Good". Additionally they reported that ErgoROM had a positive impact on active learning and critical thinking.

  4. La iglesia de San Miguel en Caltojar. El Románico en transición

    Directory of Open Access Journals (Sweden)

    Utrero Agudo, María de los Ángeles

    2014-12-01

    Full Text Available The church of San Miguel in Caltojar belongs to a large group of Romanesque architecture sited in the province of Soria. Simple in form and scale, only the sculpture of its southern main door has been approached by those few researchers engaged in its study. However, this building owns a sequence with two original building phases, dated to the late 12th and early 13th centuries, and numerous later modifications, standing out the vaults of the naves introduced in the modern period, not in the medieval one as it had been hitherto thought.La iglesia de San Miguel en Caltojar forma parte del amplio conjunto de arquitectura románica que puebla la provincia de Soria. De forma y escala sencillas, únicamente la decoración de su portada meridional ha llamado la atención de los escasos investigadores que se han ocupado de ella. Sin embargo, este edificio encierra una secuencia con dos fases originales de obra, atribuibles a finales del siglo XII e inicios del XIII, y un número importante de modificaciones posteriores, entre las cuales destacan las cubiertas abovedadas de las naves introducidas en época moderna, y no en época medieval como se había propuesto hasta hoy.

  5. EFFECTS OF POSTEROANTERIOR LUMBAR SPINE MOBILIZATIONS ON PAIN, ROM AND FUNCTIONAL DISABILITY IN FEMALE SUBJECTS WITH CHRONIC NONSPECIFIC LOW BACK PAIN

    Directory of Open Access Journals (Sweden)

    C. Shanthi

    2014-12-01

    Full Text Available Background: Chronic nonspecific low back pain (CNSLBP i.e., low back pain of at least 12 weeks duration without a specific cause is a major cause of activity limitation, absenteeism , and high health care expenses. The prevalence of CNSLBP is estimated approximately 23% and activity limitation due to LBP have been found to be 11% to 12% of the population. Previous studies comparing the efficacy of postero-anterior mobilisation and prone-press ups were done and revealed statistically significant improvements in extension ranges but not clinical relevant improvements. This is possibly attributable to single session of interventions. So long term gains in pain reduction and lumbar extension cannot be assumed. Hence this study would be intending to prove the effect of postero-anterior mobilisation and prone press ups on chronic non-specific low back pain after 6 weeks and their clinical application. Method: 30 subjects who met the inclusion criteria were selected randomly from the department of physiotherapy, SVIMS and BIRRD, Tirupati. The study conducted for a period of 6 weeks.2 groups were formed with 15 in each group. PA lumbar glide and prone press up's was given to group I and only prone press up's was given to group II. Subjects were evaluated pre and post treatment for VAS, extension ROM of lumbar spine and functional disability. Result: Results showed that there exists a statistical significance between the groups in all the 3 parameters. Present randomized clinical trial provided evidence to support the use of postero-anterior mobilisation and prone press-ups in relieving pain, improving ROM and reducing disability in subjects with non-specific low back pain. In addition, results supported that postero-anterior mobilisation was more effective than prone press-ups.

  6. Highly Sensitive Cadmium Concentration Sensor Using Long Period Grating

    Directory of Open Access Journals (Sweden)

    A. S. Lalasangi

    2011-08-01

    Full Text Available In this paper we have proposed a simple and effective Long Period Grating chemical sensor for detecting the traces of Cadmium (Cd++ in drinking water at ppm level. Long Period gratings (LPG were fabricated by point-by-point technique with CO2 laser. We have characterized the LPG concentration sensor sensitivity for different solutions of Cd concentrations varying from 0.01 ppm to 0.04 ppm by injecting white Light source and observed transmitted spectra using Optical Spectrum Analyzer (OSA. Proper reagents have been used in the solutions for detection of the Cd species. The overall shift in wavelength is 10 nm when surrounding medium gradually changed from water to 0.04 ppm of cadmium concentrations. A comparative study has been done using sophisticated spectroscopic atomic absorption spectrometer (AAS and Inductively Coupled Plasma (ICP instruments. The spectral sensitivity enhancement was done by modifying grating surface with gold nanoparticles.

  7. In ovo injection of anti-chicken CD25 monoclonal antibodies depletes CD4+CD25+ T cells in chickens.

    Science.gov (United States)

    Shanmugasundaram, Revathi; Selvaraj, Ramesh K

    2013-01-01

    The CD4(+)CD25(+) cells have T regulatory cell properties in chickens. This study investigated the effect of in ovo injection of anti-chicken CD25 monoclonal antibodies (0.5 mg/egg) on CD4(+)CD25(+) cell depletion and on amounts of interleukin-2 mRNA and interferon-γ mRNA in CD4(+)CD25(-) cells posthatch. Anti-chicken CD25 or PBS (control) was injected into 16-d-old embryos. Chicks hatched from eggs injected with anti-chicken CD25 antibodies had a lower CD4(+)CD25(+) cell percentage in the blood until 25 d posthatch. The anti-chicken CD25 antibody injection nearly depleted CD4(+)CD25(+) cells in the blood until 16 d posthatch. At 30 d posthatch, the CD4(+)CD25(+) cell percentage in the anti-CD25-antibody-injected group was comparable with the percentage in the control group. At 16 d posthatch, the anti-chicken CD25 antibody injection decreased CD4(+)CD25(+) cell percentages in the thymus, spleen, and cecal tonsils. Chickens hatched from anti-CD25-antibody-injected eggs had approximately 25% of CD4(+)CD25(+) cells in the cecal tonsils and thymus compared with those in the cecal tonsils and thymus of the control group. The CD4(+)CD25(-) cells from the spleen and cecal tonsils of chicks hatched from anti-chicken-CD25-injected eggs had higher amounts of interferon-γ and interleukin-2 mRNA than CD4(+)CD25(-) cells from the control group. It could be concluded that injecting anti-chicken CD25 antibodies in ovo at 16 d of incubation nearly depleted the CD4(+)CD25(+) cells until 25 d posthatch.

  8. Combined effects of elevated CO_2 and Cd-contaminated water on growth, photosynthetic response, Cd accumulation and thiolic components status in Lemna minor L

    International Nuclear Information System (INIS)

    Pietrini, F.; Bianconi, D.; Massacci, A.; Iannelli, M.A.

    2016-01-01

    Highlights: • Elevated CO_2 did not affect the ability of L. minor plants to accumulate Cd in their tissues. • Elevated CO_2 decreased Cd toxicity in L. minor plants by increasing photosynthesis. • Elevated CO_2 reduced Cd toxicity in duckweed by enhancing antioxidant system. - Abstract: The objective of this study was to investigate the combined effects of elevated CO_2 and cadmium (Cd) treatments on growth, photosynthetic efficiency and phytoremediation ability in Lemna minor L. Plants of L. minor were exposed to different Cd concentrations (0, 1.5, 2.5 and 5 mg L"−"1 Cd) for periods of 24, 48 and 72 h at ambient (AC) and at elevated (EC) CO_2 (350 and 700 ppm, respectively). Cadmium concentration, bioconcentration factor, enzyme activities and thiols content enhanced in plants with the increase of Cd treatments, time of exposure and at both CO_2 levels. Glutathione levels increased only at AC. Growth, photosynthetic and chlorophyll fluorescence parameters, and the reduced glutathione to oxidized glutathione ratio declined in plants with increasing exposure time, Cd treatments and at both CO_2 levels. Our results suggested that the alleviation of toxicity, at low Cd doses, observed in L. minor grown at EC is dependent on both increased photosynthesis and an enhanced antioxidant capacity.

  9. Distinct and overlapping effector functions of expanded human CD4+, CD8α+ and CD4-CD8α- invariant natural killer T cells.

    Directory of Open Access Journals (Sweden)

    Vincent O'Reilly

    Full Text Available CD1d-restricted invariant natural killer T (iNKT cells have diverse immune stimulatory/regulatory activities through their ability to release cytokines and to kill or transactivate other cells. Activation of iNKT cells can protect against multiple diseases in mice but clinical trials in humans have had limited impact. Clinical studies to date have targeted polyclonal mixtures of iNKT cells and we proposed that their subset compositions will influence therapeutic outcomes. We sorted and expanded iNKT cells from healthy donors and compared the phenotypes, cytotoxic activities and cytokine profiles of the CD4(+, CD8α(+ and CD4(-CD8α(- double-negative (DN subsets. CD4(+ iNKT cells expanded more readily than CD8α(+ and DN iNKT cells upon mitogen stimulation. CD8α(+ and DN iNKT cells most frequently expressed CD56, CD161 and NKG2D and most potently killed CD1d(+ cell lines and primary leukemia cells. All iNKT subsets released Th1 (IFN-γ and TNF-α and Th2 (IL-4, IL-5 and IL-13 cytokines. Relative amounts followed a CD8α>DN>CD4 pattern for Th1 and CD4>DN>CD8α for Th2. All iNKT subsets could simultaneously produce IFN-γ and IL-4, but single-positivity for IFN-γ or IL-4 was strikingly rare in CD4(+ and CD8α(+ fractions, respectively. Only CD4(+ iNKT cells produced IL-9 and IL-10; DN cells released IL-17; and none produced IL-22. All iNKT subsets upregulated CD40L upon glycolipid stimulation and induced IL-10 and IL-12 secretion by dendritic cells. Thus, subset composition of iNKT cells is a major determinant of function. Use of enriched CD8α(+, DN or CD4(+ iNKT cells may optimally harness the immunoregulatory properties of iNKT cells for treatment of disease.

  10. Characterization of primary cutaneous CD8+/CD30+ lymphoproliferative disorders.

    Science.gov (United States)

    Martires, Kathryn J; Ra, Seong; Abdulla, Farah; Cassarino, David S

    2015-11-01

    CD30 primary cutaneous lymphoproliferative diseases include both lymphomatoid papulosis (LyP) and primary cutaneous anaplastic large cell lymphoma (PCALCL). The neoplastic cell of most primary CD30 lymphoproliferative disorders is CD4 positive. The terminology LyP "type D" has been used to describe a growing number of cases of LyP with a predominantly CD8 infiltrate. PCALCL with a CD8 phenotype has also been described, which presents a particularly difficult diagnostic and management challenge, given the difficulty in distinguishing it histologically from other cytotoxic lymphomas such as primary cutaneous aggressive epidermotropic CD8 cytotoxic T-cell lymphoma and CD8 gamma/delta and natural killer/T-cell lymphoma. We report 7 additional cases of these rare cutaneous CD8/CD30 lymphoproliferative disorders. We also present a unique case of CD8/CD30 LyP with histologic similarities to LyP type B. In all 7 of our cases of CD8 LyP and CD8 anaplastic large cell lymphoma, we found focal to diffuse MUM-1 positivity. We propose that MUM-1 may represent an adjunctive marker for CD8 lymphoproliferative disease. Finally, we review the current literature on cases of CD8 LyP and PCALCL. For the 106 cases examined, we found similar clinical and histologic features to those reported for traditional CD4CD30 LyP and PCALCL.

  11. Increased Numbers of CD4+CD25+ and CD8+CD25+ T-Cells in Peripheral Blood of Patients with Rheumatoid Arthritis with Parvovirus B19 Infection.

    Science.gov (United States)

    Naciute, Milda; Maciunaite, Gabriele; Mieliauskaite, Diana; Rugiene, Rita; Zinkeviciene, Aukse; Mauricas, Mykolas; Murovska, Modra; Girkontaite, Irute

    2017-01-01

    To investigate T-cell subpopulations in peripheral blood of human parvovirus B19 DNA-positive (B19 + ) and -negative (B19 - ) patients with rheumatoid arthritis (RA) and healthy persons. Blood samples were collected from 115 patients with RA and 47 healthy volunteers; 27 patients with RA and nine controls were B19 + Cluster of differentiation (CD) 4, 8, 25 and 45RA were analyzed on blood cells. CD25 expression on CD4 + CD45RA + , CD4 + CD45RA - , CD8 + CD45RA + , CD8 + CD45RA - subsets were analyzed by flow cytometry. The percentage of CD25 low and CD25 hi cells was increased on CD4 + CD45RA + , CD4 + CD45RA - T-cells and the percentage of CD25 + cells was increased on CD8 + CD45RA + , CD8 + CD45RA - T-cells of B19 + patients with RA in comparison with B19 - patients and controls. Raised levels of CD4 and CD8 regulatory T-cells in B19 + RA patients could cause down-regulation of antiviral clearance mechanisms and lead to activation of persistent human parvovirus B19 infection in patients with RA. Copyright© 2017, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.

  12. Electrical properties of CdS/CdTe heterojunctions

    International Nuclear Information System (INIS)

    Chu, T.L.; Chu, S.S.; Ang, S.T.

    1988-01-01

    The electrical properties of n-CdS/p-CdTe heterojunctions depend strongly on the cleanliness of the interface region. In this work, CdTe films were deposited on CdS/glass substrates by close-spaced sublimation (CSS) under various conditions. The dark current-voltage characteristics of the resulting heterojunctions were measured over a wide temperature range, and the capacitance-voltage characteristics were measured in the dark and under illumination. When the CdS surface is in situ cleaned prior to the deposition of the CdTe film, the current transport across the junction is controlled by a thermally activated process. Tunneling makes an important contribution to the interface recombination at temperatures below room temperature when the in situ cleaning of CdS is not used. The dark capacitance of CdS/CdTe heterojunctions prepared with in situ etching is essentially independent of the reverse bias due to intrinsic interface states. Under white light illumination, the 1/C 2 vs V relation is nearly linear. The CdS/CdTe heterojunctions without in situ cleaning showed different 1/C 2 vs V relations due to higher density of interface states. The in situ cleaning also has pronounced effects on the frequency dependence of dark and illuminated capacitances. Using the in situ cleaning technique, solar cells of about 1 cm 2 area have achieved an AM 1.5 (global) efficiency of about 10.5%

  13. Flow Cytometry Assessment of In Vitro Generated CD138+ Human Plasma Cells

    Directory of Open Access Journals (Sweden)

    Rayelle Itoua Maïga

    2014-01-01

    Full Text Available The in vitro CD40-CD154 interaction promotes human B lymphocytes differentiation into plasma cells. Currently, CD138 is the hallmark marker enabling the detection of human plasma cells, both in vitro and in vivo; its presence can be monitored by flow cytometry using a specific antibody. We have developed a culture system allowing for the differentiation of memory B lymphocytes. In order to detect the newly formed plasma cells, we have compared their staining using five anti-CD138 monoclonal antibodies (mAbs. As a reference, we also tested human cell lines, peripheral blood mononuclear cells, and bone marrow samples. The five anti-CD138 mAbs stained RPMI-8226 cells (>98% with variable stain index (SI. The highest SI was obtained with B-A38 mAb while the lowest SI was obtained with DL-101 and 1D4 mAbs. However, the anti-CD138 mAbs were not showing equivalent CD138+ cells frequencies within the generated plasma cells. B-A38, B-B4, and MI-15 were similar (15–25% while DL-101 mAb stained a higher proportion of CD138-positive cells (38–42%. DL-101 and B-A38 mAbs stained similar populations in bone marrow samples but differed in their capacity to bind to CD138high and CD138lo cell lines. In conclusion, such cellular fluctuations suggest heterogeneity in human plasma cell populations and/or in CD138 molecules.

  14. CD4/CD8/Dendritic cell complexes in the spleen: CD8+ T cells can directly bind CD4+ T cells and modulate their response

    Science.gov (United States)

    Barinov, Aleksandr; Galgano, Alessia; Krenn, Gerald; Tanchot, Corinne; Vasseur, Florence

    2017-01-01

    CD4+ T cell help to CD8+ T cell responses requires that CD4+ and CD8+ T cells interact with the same antigen presenting dendritic cell (Ag+DC), but it remains controversial whether helper signals are delivered indirectly through a licensed DC and/or involve direct CD4+/CD8+ T cell contacts and/or the formation of ternary complexes. We here describe the first in vivo imaging of the intact spleen, aiming to evaluate the first interactions between antigen-specific CD4+, CD8+ T cells and Ag+DCs. We show that in contrast to CD4+ T cells which form transient contacts with Ag+DC, CD8+ T cells form immediate stable contacts and activate the Ag+DC, acquire fragments of the DC membranes by trogocytosis, leading to their acquisition of some of the DC properties. They express MHC class II, and become able to present the specific Marilyn peptide to naïve Marilyn CD4+ T cells, inducing their extensive division. In vivo, these CD8+ T cells form direct stable contacts with motile naïve CD4+ T cells, recruiting them to Ag+DC binding and to the formation of ternary complexes, where CD4+ and CD8+ T cells interact with the DC and with one another. The presence of CD8+ T cells during in vivo immune responses leads to the early activation and up-regulation of multiple functions by CD4+ T lymphocytes. Thus, while CD4+ T cell help is important to CD8+ T cell responses, CD8+ T cells can interact directly with naïve CD4+ T cells impacting their recruitment and differentiation. PMID:28686740

  15. Synthesis, structures and electroluminescence properties of CdS:In/Si nanoheterostructure array

    Energy Technology Data Exchange (ETDEWEB)

    Yan, Ling Ling; Cai, Hong Xin; Chen, Liang [Henan Polytechnic University, School of Physics and Electronic Information Engineering, Jiaozuo (China)

    2017-10-15

    An In-doped CdS/Si nanoheterojunction (CdS:In/Si-NPA) is prepared by depositing an In-doped CdS thin film onto a Si nanoporous pillar array (Si-NPA) via a successive ionic layer adsorption and reaction method. Based on the measured J-V characteristic curve, the nanoheterojunction exhibits a good rectifying behavior with a low forward turn-on voltage (2.2 V), a small leakage current density (0.5 mA/cm{sup 2} at - 3 V) and a high reverse breakdown voltage (> 8 V). The electroluminescence (EL) measurements reveal that a broadband emerges between 400 and 700 nm, and this band is confirmed as a white light emission based on the value of the chromaticity coordinate. The EL properties, including the CIE chromaticity coordinates, Colour Rendering Index and correlated color temperature, can be tuned by the applied voltage. The generation mechanism of the EL can be well interpreted depending on the energy band structure of CdS:In/Si-NPA. The green band should be attributed to the band-edge emission of CdS and the yellow emission may be related to Cd interstitial. These results highlight the potential of CdS:In/Si-NPA as a light source for future white light emitting devices. (orig.)

  16. Expressão citofotométrica dos marcadores tumorais Ki-67 e CD34 no adenocarcinoma de estômago Citophotometric expression of tumoral markers: Ki67 and CD34 in stomach adenocarcinoma

    Directory of Open Access Journals (Sweden)

    José Augusto Menezes Freitas de Campos

    2007-09-01

    ,000 inhabitants. AIM: To describe the cytophotometric expression of Ki-67 and CD-34 with comparison to their expression in stomach adenocarcinomas. METHODS: 60 paraffin blocks containing specimens of gastric adenocarcinomas, were initially selected in the Pathology services of the Gama Hospital - Brasília, DF an at the Dom Orione Hospital - Araguaiana, TO. The immunohistochemistry process using Ki-67 and CD-34 was performed at the Laboratório de Citologia e Histopatologia Ltda. -CITOLAB, Curitiba, PR. A total of 35 paraffin blocks were selected among the other 60 previously selected, being used in histological studies as well as for the immunohistochemistry process. These were analyzed using the computerized image cytophotometric system (SAMBA 4000 at the Institute of Medical Research of the Hospital Universitário Evangélico de Curitiba. The parameters studies and analyzed through this system were the labeling index and optical density for both of the tumoral markers being independently analyzed and latter compared with each other. RESULTS: Of the 35 slides, 15(42,85% showed the expression of Ki-67; 26 (74,28% of CD-34 and 12 slides (34,28% showed the expression of both markers. When the labeling indexes between Ki-67 and CD-34 were compared, a significant difference was observed (P<0,001 favoring CD-34. When the optical density of the two markers was compared, a significant difference (P<0,001 was also observed, favoring CD-34. CONCLUSIONS: The average labeling index for Ki-67 was of 36,85%, where as the optical density was of 29,33 pixels. CD-34 showed a labeling index of 84,86% and an average 49,84 pixels regarding the optical density. When the labeling index and optical density were compared between both of the markers, a significant difference was established favoring CD-34 in both of the parameters analyzed.

  17. Metal pollution (Cd, Pb, Zn, and As) in agricultural soils and soybean, Glycine max, in southern China.

    Science.gov (United States)

    Zhao, Yunyun; Fang, Xiaolong; Mu, Yinghui; Cheng, Yanbo; Ma, Qibin; Nian, Hai; Yang, Cunyi

    2014-04-01

    Crops produced on metal-polluted agricultural soils may lead to chronic toxicity to humans via the food chain. To assess metal pollution in agricultural soils and soybean in southern China, 30 soybean grain samples and 17 soybean-field soil samples were collected from 17 sites in southern China, and metal concentrations of samples were analyzed by graphite furnace atomic absorption spectrophotometer. The integrated pollution index was used to evaluate if the samples were contaminated by Cd, Pb, Zn and As. Results showed that Cd concentration of 12 samples, Pb concentration of 2 samples, Zn concentration of 2 samples, and As concentrations of 2 samples were above the maximum permissible levels in soils. The integrated pollution index indicated that 11 of 17 soil samples were polluted by metals. Metal concentrations in soybean grain samples ranged from 0.11 to 0.91 mg kg(-1) for Cd; 0.34 to 2.83 mg kg(-1) for Pb; 42 to 88 mg kg(-1) for Zn; and 0.26 to 5.07 mg kg(-1) for As, which means all 30 soybean grain samples were polluted by Pb, Pb/Cd, Cd/Pb/As or Pb/As. Taken together, our study provides evidence that metal pollution is an important concern in agricultural soils and soybeans in southern China.

  18. CdS/CdSSe quantum dots in glass matrix

    Indian Academy of Sciences (India)

    CdSSe and melted at 1200–1300°C. The glass samples were transparent and pale yellow in colour due to presence of CdS/CdSSe tiny nano crystal (Q-dots). in situ growth of CdS/CdSSe nano crystals imparts the yellow/orange/red colour to ...

  19. CD133 expression in well-differentiated pancreatic neuroendocrine tumors: a potential predictor of progressive clinical courses.

    Science.gov (United States)

    Sakai, Yasuhiro; Hong, Seung-Mo; An, Soyeon; Kim, Joo Young; Corbeil, Denis; Karbanová, Jana; Otani, Kyoko; Fujikura, Kohei; Song, Ki-Byung; Kim, Song Cheol; Akita, Masayuki; Nanno, Yoshihide; Toyama, Hirochika; Fukumoto, Takumi; Ku, Yonson; Hirose, Takanori; Itoh, Tomoo; Zen, Yoh

    2017-03-01

    The present study aimed to elucidate whether the stemness molecule, CD133, is expressed in well-differentiated pancreatic neuroendocrine tumors (PanNETs; World Health Organization grades 1 and 2) and establish its clinical relevance using 2 separate cohorts. In the first series (n = 178) in which tissue microarrays were available, immunohistochemistry revealed that CD133 was expressed in 14 cases (8%). CD133+ PanNETs had higher TNM stages (P < .01), more frequent lymphovascular invasion (P = .01), and higher recurrence rates (P = .01). In the second cohort (n = 56), the expression of CD133 and CK19 was examined in whole tissue sections. CD133 and CK19 were positive in 10 (18%) and 36 (64%) cases, respectively. CD133 expression correlated with higher pT scores (P < .01), the presence of microscopic venous infiltration (P = .03), and shorter disease-free periods (P < .01). When cases were divided into grade 1 and 2 neoplasms, patients with CD133+ PanNET continued to have shorter disease-free periods than did those with CD133- tumors in both groups (P < .01 and P = .02, respectively). Although CK19+ cases had shorter disease-free periods than did CK19- cases in the whole cohort (P = .02), this difference was less apparent in subanalyses of grade 1 and 2 cases. CD133 expression also appeared to be an independent predictive factor for tumor recurrence in a multivariate analysis (P = .018). The CD133 phenotype was identical between primary and metastatic foci in 17 of 18 cases from which tissues of metastatic deposits were available. In conclusion, the combination of CD133 phenotyping and World Health Organization grading may assist in stratifying patients in terms of the risk of progressive clinical courses. Copyright © 2016 Elsevier Inc. All rights reserved.

  20. Standing Wave Field Distribution in Graded-Index Antireflection Coatings

    Directory of Open Access Journals (Sweden)

    Hongxiang Deng

    2018-01-01

    Full Text Available Standing wave field distributions in three classic types of graded-index antireflection coatings are studied. These graded-index antireflection coatings are designed at wavelengths from 200 nm to 1200 nm, which is the working wavelength range of high energy laser system for inertial-fusion research. The standing wave field distributions in these coatings are obtained by the numerical calculation of electromagnetic wave equation. We find that standing wave field distributions in these three graded-index anti-reflection coatings are quite different. For the coating with linear index distribution, intensity of standing wave field decreases periodically from surface to substrate with narrow oscillation range and the period is proportional to the incident wavelength. For the coating with exponential index distribution, intensity of standing wave field decreases periodically from surface to substrate with large oscillation range and the period is also proportional to the incident wavelength. Finally, for the coating with polynomial index, intensity of standing wave field is quickly falling down from surface to substrate without an obvious oscillation. We find that the intensity of standing wave field in the interface between coating and substrate for linear index, exponential index and polynomial index are about 0.7, 0.9 and 0.7, respectively. Our results indicate that the distributions of standing wave field in linear index coating and polynomial index coating are better than that in exponential index coating for the application in high energy laser system. Moreover, we find that the transmittance of linear index coating and polynomial index coating are also better than exponential index coating at the designed wavelength range. Present simulation results are useful for the design and application of graded-index antireflection coating in high energy laser system.