Enhancing Your CD-ROM Services with Signage Systems.

Science.gov (United States)

Ekhaml, Leticia

1994-01-01

Describes how to use effective signage, or visual guidance, for more efficient use of CD-ROM technology in elementary and secondary school library media centers. Setting CD-ROM policies and procedures is considered; the use of posters, brochures, flowcharts, and other formats is discussed; and examples are included. (LRW)

CD-ROM storing JENDL-3.2 plots and data

Energy Technology Data Exchange (ETDEWEB)

Fukahori, Tokio; Iwamoto, Osamu; Nakagawa, Tsuneo; Shibata, Keiichi; Narita, Tsutomu; Katakura, Jun-ichi; Hasegawa, Akira [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

1998-01-01

Numerical data and graphs of Japanese Evaluated Nuclear Data Library, Version 3, Revision 2 (JENDL-3.2) have been stored into CD-ROM. JENDL-3.2 is an evaluated nuclear data library which is highly rated in the world, and consists of neutron nuclear data and secondary gamma-ray data for 340 nuclides. JENDL-3.2 has been already released through World Wide Web (WWW, http://cracker.tokai.jaeri.go.jp). For users` convenience and to promote further utilization, this CD-ROM has been produced. The data stored in CD-ROM are the original data and point-wise data (0 K and 300 K) of JENDL-3.2 and graphs of cross sections in gif, PostScript and PDF formats. These data can be retrieved by users` personal computers and engineering workstations, and also can be seen by using WWW browsers. This CD-ROM makes user completely free from downloading, which takes a lot of time, and tedious management such a treating big amount of data. (author)

Scaffolding or Distracting: CD-ROM Storybooks and Young Readers

Science.gov (United States)

Pearman, Cathy J.; Chang, Ching-Wen

2010-01-01

CD-ROM storybooks, often referred to as electronic texts, e-books, and interactive stories, are learning tools with supplemental features such as automatic reading of text, sound effects, word pronunciations, and graphic animations which support the development of reading skills and comprehension in beginning readers. Some CD-ROM storybooks also…

Review of CD Rom

African Journals Online (AJOL)

"The Virtual Surgeon consists of a ground breaking series of CD-ROMs, which aims to provide surgeons with a new and powerful training tool. It provides surgeons with the most accurate and realistic model of the knee available, and our developments in animation allow them to see all aspects of the surgical procedure.

OCONUS Compliance Assessment Protocols - Qatar (Army Version) (CD-ROM)

National Research Council Canada - National Science Library

Krooks, David A

2004-01-01

...: 1 CD-ROM; 4 3/4 in.; 578 KB. ABSTRACT: This environmental compliance assessment manual is based on the Final Governing Standards for Environmental Security of United States Forces in the State of Qatar, 21 May 1999, and the Overseas...

The systems prioritization method (SPM) CD-ROM demonstration for Waste Management '96

International Nuclear Information System (INIS)

Harris, C.L.; Boak, D.M.; Prindle, N.H.; Beyeler, W.

1996-01-01

In March 1994, the Department of Energy Carlsbad Area Office (DOE/CAO) implemented a performance-based planning method to assist in prioritization within the Waste Isolation Pilot Plant (WIPP). Probabilistic performance calculations were required for the Systems Prioritization Method (SPM) and roughly 46,700 combinations of activities were analyzed, generating a large volume of information to be documented, analyzed, and communicated. A self-contained information management system consisting of a relational database on a 600-megabyte CD-ROM was built to meet this need. The CD-ROM was used to store performance assessment results, data analysis and visualization tools, information about the activities, electronic copies of 40 ILFR 191 and 40 CFR 268, technical reference papers, and the final SPM report. Copies of the CD-ROM were distributed to interested members of the public, WIPP participants, and the Environmental Protection Agency (EPA)

Natural Tasking of Robots Based on Human Interaction Cues (CD-ROM)

National Research Council Canada - National Science Library

Brooks, Rodney A

2005-01-01

...: 1 CD-ROM; 4 3/4 in.; 207 MB. ABSTRACT: We proposed developing the perceptual and intellectual abilities of robots so that in the field, war-fighters can interact with them in the same natural ways as they do with their human cohorts...

New Access Points to ERIC--CD-ROM Versions. ERIC Digest.

Science.gov (United States)

McLaughlin, Pamela W.

This digest reviews three CD-ROM (compact disc-read only memory) versions of the ERIC (Educational Resources Information Center) database currently being delivered or tested and provides information for comparison. However, no attempt is made to recommend any one product. The advantages and disadvantages of the acquisition of CD-ROM databases are…

Data on the environment. Accompanying brochure of the CD ROM; Daten zur Umwelt. Begleitbroschuere zur CD-ROM

Energy Technology Data Exchange (ETDEWEB)

NONE

2009-07-15

During the past 25 years, the Federal Environmental Office (UBA) has been publishing annual data on the environmental situation in Germany. This is the most recent publication; it contains data on climate protection, resources management, environment, health and quality of life, natural cycles and environmental media, and the economic importance of environmental protection. The CD-ROM contains data and facts on all of these subjects. It provides detailed and comprehensive information on the current condition of the environment in Germany, strategies and goals of environmental policy, books and other publications for further reading, and links. The CD-ROM also contains a system of key environmental indicators which illustrates successful activities and needs for action of environmental policy. Integrated internet access ensures access to current information on the internet. (orig.)

A condensed review of the manageral aspects of CD-ROM network system

Energy Technology Data Exchange (ETDEWEB)

Choi, Kwang

2001-10-01

This report discussed manageral aspects of CD-ROM Network system to reduce executing errors and to provide effective information services to users. The results of this study are follows. 1) Library has to decide the type fo cd-rom network system compatible to the library. 2) A way of acquiring of system purchasing budget is commom utility budgets and has to include system maintenance budget. 3) When decides a provider, it is needed to review price, maintenance ability, statistics s/w, anti-virus functions.4) System manager would be a one wide-range of knowledge about network, equipment, s/w and needs continuous education about system. 5) The system users are required to have more basic knowledge than general users other users, library has to provide various user educations and minute user manuals. 6) Purchasing of CD-ROM for network use is essential and cost-benefit analysis between on-line DB and cd-rom for one user are needed. 7) when constructing Local DB using CD-RM NETWORK SYSTEM, library give attention to copyrigths of the cd-rom. 8) To provide good services through the system, cross cooperation between library and related departments is required.

SCUTREA Conference Proceedings, 1970-1997. 25th Anniversary CD-ROM.

Science.gov (United States)

Standing Conference on Univ. Teaching and Research in the Education of Adults.

This CD-ROM contains 693 papers on university teaching and research in the education of adults that were presented during the 27-year period from 1970 through 1997. The CD-ROM is designed to be used with the Macintosh, Windows 95, and Windows 3.1 operating systems and Adobe Acrobat Portable Document Format (version 3), which is included along with…

Qualitative evaluation of a colorectal cancer education CD-ROM for Community Health Aides/practitioners in Alaska.

Science.gov (United States)

Cueva, Melany; Dignan, Mark; Lanier, Anne; Kuhnley, Regina

2014-12-01

Colorectal cancer (CRC) is an important contributor to the cancer burden among Alaska Native people. CRC is the leading incident cancer and the second leading cause of cancer mortality among Alaska Native people. Completing recommended CRC screening procedures has the potential to reduce both CRC incidence and mortality. "Taking Action Colorectal Health," a multidimensional audiovisual, interactive CD-ROM, incorporates adult education learning principles to provide Alaska's Community Health Aides/Practitioners with timely, medically accurate, and culturally relevant CRC place-based education. Providing this resource on CD-ROM empowers learning within communities and places where people live or choose to learn. The dynamic process of developing, implementing, and evaluating this CRC CD-ROM was informed by a sociocultural approach to share health messages. Within this approach, cultural values, beliefs, and behaviors are affirmed as a place of wisdom and resilience and built upon to provide context and meaning for health messaging. Alaska Native values that honor family, relationships, the land, storytelling, and humor were included in CD-ROM content. Between January and May 2012, 20 interviews were conducted with individuals who had used the CD-ROM. Four categorical themes emerged from analysis of interview transcripts: likeability, utilization, helpfulness, and behavior change. As a result of self-paced learning through stories, movies, and interactive games, respondents reported healthy behavior changes they were making for themselves, with their families and in their patient care practices. This CD-ROM is a culturally based practical course that increased knowledge and activities around colorectal cancer screening by Community Health Aides/Practitioners in Alaska.

Type 1 Diabetes in Children: A Passport to Knowledge. [CD-ROM].

Science.gov (United States)

2001

This educational CD-ROM is designed to provide a working knowledge of diabetes and its effect on children. It is intended for parents, health care professionals, pharmacists, teachers, coaches, and child care providers. The CD-ROM examines issues related to diabetes management (food, insulin, monitoring, hypoglycemia, and illness); lifestyle; and…

NODC Standard Product: NODC Taxonomic Code on CD-ROM (NODC Accession 0050418)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — The content of the NODC Taxonomic Code, Version 8 CD-ROM (CD-ROM NODC-68) distributed by NODC is archived in this accession. Version 7 of the NODC Taxonomic Code...

Development and Evaluation of a Multimedia CD-ROM for Exercise During Pregnancy and Postpartum

Science.gov (United States)

Hausenblas, Heather A.; Brewer, Britton W.; Van Raalte, Judy L.; Cook, Brian; Downs, Danielle Symons; Weis, Carol Ann; Nigg, Claudio; Cruz, Amelia

2008-01-01

Objective To meet the need for an interactive product on exercise during pregnancy and postpartum, we developed and evaluated a personally-tailored multimedia CD-ROM. Methods Pregnant and postpartum women, who were randomly assigned to either the experimental group (PregXercise™ CD-ROM) or the control group (CD-ROM with neutral content), navigated through the CD-ROM for 1 hour. Main outcomes were exercise self-efficacy and knowledge. Results In analyses of covariance, compared with the control group, the experimental group had significant increases in self-efficacy and knowledge. Conclusion The multimedia CD-ROM delivering information about exercise motivation, guidelines, and prescription was effective in improving exercise self-efficacy and knowledge. Practice Implications Our preliminary results illustrate that healthcare professionals and researchers may use interactive multimedia for improving exercise behavior and related outcomes with pregnant and postpartum women. PMID:18068940

Reta'maxik Qatzij--Conociendo Nuestro Idioma (Knowing Our Language). [CD-ROM].

Science.gov (United States)

Academy for Educational Development, Washington, DC.

This CD-ROM is part of an interactive and dynamic multimedia package of information and games for learning K'iche' and Ixil. This CD-ROM includes six books in electronic format with interactive exercises that support improved bilingual and intercultural education and teacher training, specifically in the languages of K'iche' and Ixil. Books…

An x ray archive on your desk: The Einstein CD-ROM's

Science.gov (United States)

Prestwich, A.; Mcdowell, J.; Plummer, D.; Manning, K.; Garcia, M.

1992-01-01

Data from the Einstein Observatory imaging proportional counter (IPC) and high resolution imager (HRI) were released on several CD-ROM sets. The sets released so far include pointed IPC and HRI observations in both simple image and detailed photon event list format, as well as the IPC slew survey. With the data on these CD-ROMS's the user can perform spatial analysis (e.g., surface brightness distributions), spectral analysis (with the IPC event lists), and timing analysis (with the IPC and HRI event lists). The next CD-ROM set will contain IPC unscreened data, allowing the user to perform custom screening to recover, for instance, data during times of lost aspect data or high particle background rates.

Pricing Strategies for CD-ROM Products.

Science.gov (United States)

Rowley, J. E.

1994-01-01

Pricing strategies for subscriptions and licenses for CD-ROMs are different for single users and networks. The basic components of pricing strategies are charges for subscription, connect line, display/print, telecommunication, session rate, special commands, and special services. Highlights selected supplier pricing strategies for single users…

The Virtual Man Project's CD-ROM "Voice Assessment: Speech-Language Pathology and Audiology & Medicine", Vol.1

Directory of Open Access Journals (Sweden)

Millena Maria Ramalho Matta Vieira

2009-01-01

contents after studying the CD-ROM. Based on this, it is assumed that this didactic material is an effective instrument for self-learning of this population.

OCONUS Compliance Assessment Protocols (OCAP) - Saudi Arabia (Army Version) (CD-ROM)

National Research Council Canada - National Science Library

Krooks, David A; Schell, Donna J

2004-01-01

...: 1 CD-ROM; 4 3/4 in.; 670 KB. ABSTRACT: This environmental compliance assessment manual is based on the Final Governing Standards for Environmental Security by United States Forces in the Kingdom of Saudi Arabia (FGS-SA...

CD-ROM technology at the EROS data center

Science.gov (United States)

Madigan, Michael E.; Weinheimer, Mary C.

1993-01-01

The vast amount of digital spatial data often required by a single user has created a demand for media alternatives to 1/2" magnetic tape. One such medium that has been recently adopted at the U.S. Geological Survey's EROS Data Center is the compact disc (CD). CD's are a versatile, dynamic, and low-cost method for providing a variety of data on a single media device and are compatible with various computer platforms. CD drives are available for personal computers, UNIX workstations, and mainframe systems, either directly connected, or through a network. This medium furnishes a quick method of reproducing and distributing large amounts of data on a single CD. Several data sets are already available on CD's, including collections of historical Landsat multispectral scanner data and biweekly composites of Advanced Very High Resolution Radiometer data for the conterminous United States. The EROS Data Center intends to provide even more data sets on CD's. Plans include specific data sets on a customized disc to fulfill individual requests, and mass production of unique data sets for large-scale distribution. Requests for a single compact disc-read only memory (CD-ROM) containing a large volume of data either for archiving or for one-time distribution can be addressed with a CD-write once (CD-WO) unit. Mass production and large-scale distribution will require CD-ROM replication and mastering.

Networking CD-ROMs: The Decision Maker's Guide to Local Area Network Solutions.

Science.gov (United States)

Elshami, Ahmed M.

In an era when patrons want access to CD-ROM resources but few libraries can afford to buy multiple copies, CD-ROM local area networks (LANs) are emerging as a cost-effective way to provide shared access. To help librarians make informed decisions, this manual offers information on: (1) the basics of LANs, a "local area network primer";…

Adventures in Evaluation: Reviewing a CD-ROM Based Adventure Game Designed for Young People Recovering from Psychosis

Science.gov (United States)

Shrimpton, Bradley; Hurworth, Rosalind

2005-01-01

Recently the Centre for Program Evaluation (CPE) at the University of Melbourne was approached by a mental health agency to undertake the unique and challenging task of evaluating a prototype CD-ROM based adventure game designed for young people recovering from psychosis. This unusual and inventive game, titled Pogo's Pledge, used…

Marketing and Selling CD-ROM Products on the World-Wide Web.

Science.gov (United States)

Walker, Becki

1995-01-01

Describes three companies' approaches to marketing and selling CD-ROM products on the World Wide Web. Benefits include low overhead for Internet-based sales, allowance for creativity, and ability to let customers preview products online. Discusses advertising, information delivery, content, information services, and security. (AEF)

Planning and Preparation for CD-ROM Implementation: The Citadel Library.

Science.gov (United States)

Maynard, J. Edmund

Management guidelines for library planning and a strategic planning program profile based on the literature were used in the planning process for implementing access to databases on CD-ROM at the Daniel Library of the Citadel, Military College of South Carolina. According to this model, the planning process would consist of five stages: (1)…

The Basic Economics of CD-ROM Pricing.

Science.gov (United States)

Erkkila, John E.

1991-01-01

This explanation of how the basic economic model of pricing applies to the CD-ROM industry considers the supply and demand sides of the market and compares three distinct pricing strategies: (1) pricing to maximize profits; (2) average cost pricing; and (3) marginal cost pricing. (EAM)

Ionospheric data available on CD-ROM and on NDADS

International Nuclear Information System (INIS)

Bilitza, D.

1996-01-01

Information is provided on two CD-ROMs (for PCs) with ionospheric data: the ionosonde CD issued by NGDC/WDC-A-STP/NOAA/Boulder and the Atmosphere Explorer CD produced by NSSDC/WDC-A-R and S/NASA/Greenbelt. We also briefly describe the ionospheric/thermospheric data available through NSSDC's automated mail retrieval system (NDADS) and explain the procedure for obtaining NDADS data. (author). 3 figs

Computer Based Radiation Protection- A New Cd-Rom

International Nuclear Information System (INIS)

Geringer, T.; Bammer, M.; Ablber, M.

2004-01-01

Within the next few years, there'll be a lot of new challenges required from radiation protection. According to EU regulation[1] and the new austrian radiation protection law [2] regular additional training are requested. Patients protection in diagnostic and therapeutic usage of ionising radiation gains also more and more importance.[3] Not really surprisingly, the general population is definitely highly aware of the risks coming with the usage of radionuclides and x-rays in medicine. Furthermore, the nuclear power plant in Temelin, near the austrian border initiated a lively discussion about risks, necessity and use of ionising radiation in medicine and industry. It turned out to be a really hard job handling these topics in public. A brilliant didactics based on independent information and viewpoints was required. ARC Seibersdorf Research GmbH, represented by the department of medical technical applications and the radiation protection academy, developed an interactive CD-ROM covering several applications: Basics on radiation protection for medical and technical personnel ; preparation for a radiation protection training. Repetition of the main topics for graduates of a radiation protection training. Basics on radiation protection and emergency management for medical staff as well as for the general public. (Author)

Review of Cornaline de l'Inde/Carnelian in India CD-Rom.

Directory of Open Access Journals (Sweden)

Peter Grave

2002-10-01

Full Text Available The CD-Rom format has been around for some time now with CD-Rom readers a standard fitting on even the most basic PC. The strength of this technology is that it enables large amounts of data to be stored (650-700 MB on a reliable, portable and economical medium. The character of data stored is virtually only dependant on developments in the hardware and software used to generate and manage datasets, whether numeric arrays, databases, digital imagery or multimedia. These features have made it a popular mode for a diverse range of interactive educational, reference and entertainment software. As a medium that can hold thousand of 'pages' of text, spreadsheets, colour images, animations and digital movies, CD-Rom technology also offers obvious benefits for the delivery of the diversity of data produced by archaeological research. It is surprising then that projects such as the bilingual Cornaline de l'Inde/Carnelian in India are few and far between.

Studi Korelasi Motivasi Pengguna Dengan Pemanfaatan Koleksi CD-ROM Di UPT Pusat Perpustakaan UII Yogyakarta (Study on Correlation Between The Motivation of Users and The Use of CD-ROM Collection At The Main Library of Indonesia Islamic University of Yogyakarta

Directory of Open Access Journals (Sweden)

Keni Hesti Handayani

2015-12-01

Full Text Available The research addresses three main issues: student motivation of Indonesia Islamic University of Yogyakarta, the use of CD-ROM collection at the main library of Indonesia Islamic University of Yogyakarta, and the correlation between student motivation and the use of CD-ROM collection at the library. The study uses a field research. The sample is accidental sampling which involves students using the collection of CD-ROM at the library. In the term of data collection, the writer uses some techniques those of which are documentation, observation, interview and questionnaire. The result of the research shows that, there are correlation between the motivation and the use of CD-ROM collection at the main library of Indonesia Islamic University of Yogyakarta. The research is hoped to contribute to the improvement of services of CD-ROM collection at library in particular and to the development of through collection at the library. Keyword: user motivation, the use of CD-ROM collection

Use of CD-Rom databases by staff and students in the University of ...

African Journals Online (AJOL)

The focus of this study is the use of CD-ROM databases by staff and students in the university of Jos library. This is of interest as CD-ROM database services is in consonant with the vision of providing excellent and effective information services to all staff and students of university of Jos. The study was guided by six ...

Public census data on CD-ROM at Lawrence Berkeley Laboratory

Energy Technology Data Exchange (ETDEWEB)

Merrill, D.W.

1992-07-02

In connection with the Comprehensive Epidemiologic Data Resource (CEDR) and Populations at Risk to Environmental Pollution (PAREP) projects, of the Information and Computing Sciences Division (ICSD) at Lawrence Berkeley Laboratory (LBL), are using public socioeconomic and geographic data files which are available to CEDR and PAREP collaborators via LBL's computing network. At this time 67 CD-ROM diskettes (approximately 35 gigabytes) are on line via the Unix file server cedrcd.lbl.gov. Most of the files are from the US Bureau of the Census, and most pertain to the 1990 Census of Population and Housing. This paper contains a list of the CD-ROMs available.

Dea Computrix - another deity for the Roman Pantheon? Journeys in the Roman Empire CD-Rom

Directory of Open Access Journals (Sweden)

T. Sam N. Moorhead

2002-08-01

Full Text Available This article outlines a personal view on the content and production of a CD-Rom on the Roman world produced by The British Museum, Channel 4, Verulamium Museum and Braunarts: Journeys in the Roman Empire. I discuss some of the benefits of and problems with multimedia production and outline feedback from various evaluation projects of the CD-Rom. I also briefly discuss the future of CD-Roms in the face of a rapidly expanding internet with reference to other multimedia projects at The British Museum.

Evaluation of the acceptability of a CD-Rom as a health promotion tool for Inuit in Ottawa.

Science.gov (United States)

McShane, Kelly E; Smylie, Janet K; Hastings, Paul D; Prince, Conrad; Siedule, Connie

2013-01-01

There are few health promotion tools for urban Inuit, and there is a specific dearth of evaluations on such tools. The current study used a community-specific approach in the evaluation of a health promotion tool, based on an urban Inuit community's preferences of health knowledge sources and distribution strategies. In partnership with the Tungasuvvingat Inuit Family Health Team in Ottawa, a CD-Rom was developed featuring an Inuk Elder presenting prenatal health messages in both Inuktitut and English. Also, relevant evaluation materials were developed. Using a mixed methods approach, 40 participants completed interviews prior to viewing the CD-Rom and participated in a focus group at follow-up. Questionnaires were also completed pre- and post-viewing to assess changes between expectations and reactions in order to document acceptability. Significant increases were found on satisfaction, acceptability of medium and relevance of content ratings. Qualitative findings also included (a) interest, uncertainty and conditional interest prior to viewing; and (b) positive evaluations of the CD-Rom. This suggests that CD-Rom technology has the potential for health promotion for urban Inuit, and the community-specific evaluation approach yielded useful information.

Utilizing the Evaluation Process in CD-ROM Development.

Science.gov (United States)

Crews, Tena B.; Chalupa, Marilyn R.

1999-01-01

While a CD-ROM on network topologies was being developed, it was evaluated formatively by 14 office systems teachers and summatively by 23 students using it in class. Improvements in ease of use, performance, and the accuracy and clarity of content were made. (SK)

Development and testing of a CD-ROM program for improving adolescent knowledge of inflammatory bowel disease.

Science.gov (United States)

Boamah, Lynelle M; Bohren, Janet R; Pentiuk, Scott; Baker, Raymond; Yi, Michael; Moyer, M Susan

2010-05-01

The aim of this study was to design a theory-based educational program for adolescents with inflammatory bowel disease (IBD) using an interactive multimedia CD-ROM and to test its effectiveness in improving knowledge in IBD. Curriculum-based instruction using educational theory and principles was designed for adolescents on an interactive multimedia CD-ROM. Twenty subjects completed summative evaluation of the CD-ROM measuring gain in knowledge about IBD immediately and 9 months after instruction. Subjects found the CD-ROM to be informative, appealing, and easy to use. The mean baseline score of the adolescents on the Crohn's and Colitis Knowledge questionnaire was 12.2 (standard deviation 5.14, range 3-24). After an average of 30 minutes of self-directed learning, adolescent subjects increased their posttest score to a mean of 19.8, a gain of 7.6 points over baseline (95% confidence interval 5.2-10.1, P < 0.0001). Knowledge of medications, disease complications, and gastrointestinal structure and function was gained and retained upon retesting at 9 months with a mean Crohn's and Colitis Knowledge questionnaire score of 17.5 (standard deviation 3.9, range 12-26), which was still an improvement over the mean pretest knowledge score of 12.2 (P < 0.001). Adolescents with IBD have low baseline knowledge about their disease. A rigorously developed interactive educational tool is now available for instructing adolescent patients about their IBD.

Public census data on CD-ROM at Lawrence Berkeley Laboratory

Energy Technology Data Exchange (ETDEWEB)

Merrill, D.W.

1993-01-16

The Comprehensive Epidemiologic Data Resource (CEDR) and Populations at Risk to Environmental Pollution (PAREP) projects, of the Information and Computing Sciences Division (ICSD) at Lawrence Berkeley Laboratory (LBL), are using public socioeconomic and geographic data files which are available to CEDR and PAREP collaborators via LBL's computing network. At this time 72 CD-ROM diskettes (approximately 37 gigabytes) are on line via the Unix file server cedrcd.lbl.gov''. Most of the files are from the US Bureau of the Census, and many of these pertain to the 1990 Census of Population and Housing. All the CD-ROM diskettes contain documentation in the form of ASCII text files. In addition, printed documentation for most files is available for inspection at University of California Data and Technical Assistance (UC DATA), tel. (510) 642-6571, or the UC Documents Library, tel. (510) 642-2569, both located on the UC Berkeley Campus. Many of the CD-ROM diskettes distributed by the Census Bureau contain software for PC compatible computers, for easily accessing the data. Shared access to the data is maintained through a collaboration among the CEDR and PAREP projects at LBL, and UC DATA, and the UC Documents Library. LBL is grateful to UC DATA and the UC Documents Library for the use of their CD-ROM diskettes. Shared access to LBL facilities may be restricted in the future if costs become prohibitive. Via the Sun Network File System (NFS), these data can be exported to Internet computers for direct access by the user's application program(s). Due to the size of the files, this access method is preferred over File Transfer Protocol (FTP) access. Please contact Deane Merrill (dwmerrill lbl.gov) if you wish to make use of the data.

CD roms and multimedia projector as complimentary educational ...

African Journals Online (AJOL)

This paper examines the potentials of utilizing Compact Disk Read Only Memory (CD-ROM) and the multimedia projector as complimentary educational technology for teaching music in colleges of education in Nigeria. While recognizing the problem of ineffective methods of teaching in Nigeria's educational system, the ...

Public census data on CD-ROM at Lawrence Berkeley Laboratory

Energy Technology Data Exchange (ETDEWEB)

Merrill, D.W.

1992-10-01

The Comprehensive Epidemiologic Data Resource (CEDR) and Populations at Risk to Environmental Pollution (PAREP) projects, of the Information and Computing Sciences Division (ICSD) at Lawrence Berkeley Laboratory (LBL), are using public socio-economic and geographic data files which are available to CEDR and PAREP collaborators via LBL's computing network. At this time 70 CD-ROM diskettes (approximately 36 gigabytes) are on line via the Unix file server cedrcd. lbl. gov. Most of the files are from the US Bureau of the Census, and most pertain to the 1990 Census of Population and Housing. All the CD-ROM diskettes contain documentation in the form of ASCII text files. Printed documentation for most files is available for inspection at University of California Data and Technical Assistance (UC DATA), or the UC Documents Library. Many of the CD-ROM diskettes distributed by the Census Bureau contain software for PC compatible computers, for easily accessing the data. Shared access to the data is maintained through a collaboration among the CEDR and PAREP projects at LBL, and UC DATA, and the UC Documents Library. Via the Sun Network File System (NFS), these data can be exported to Internet computers for direct access by the user's application program(s).

Public census data on CD-ROM at Lawrence Berkeley Laboratory

Energy Technology Data Exchange (ETDEWEB)

Merrill, D.W.

1992-10-01

The Comprehensive Epidemiologic Data Resource (CEDR) and Populations at Risk to Environmental Pollution (PAREP) projects, of the Information and Computing Sciences Division (ICSD) at Lawrence Berkeley Laboratory (LBL), are using public socio-economic and geographic data files which are available to CEDR and PAREP collaborators via LBL`s computing network. At this time 70 CD-ROM diskettes (approximately 36 gigabytes) are on line via the Unix file server cedrcd. lbl. gov. Most of the files are from the US Bureau of the Census, and most pertain to the 1990 Census of Population and Housing. All the CD-ROM diskettes contain documentation in the form of ASCII text files. Printed documentation for most files is available for inspection at University of California Data and Technical Assistance (UC DATA), or the UC Documents Library. Many of the CD-ROM diskettes distributed by the Census Bureau contain software for PC compatible computers, for easily accessing the data. Shared access to the data is maintained through a collaboration among the CEDR and PAREP projects at LBL, and UC DATA, and the UC Documents Library. Via the Sun Network File System (NFS), these data can be exported to Internet computers for direct access by the user`s application program(s).

Conserving Earth's Biodiversity. [CD-ROM and] Instructor's Manual.

Science.gov (United States)

2000

This CD-ROM is designed as an interactive learning tool to support teaching in highly interdisciplinary fields such as conservation of biodiversity. Topics introduced in the software include the impact of humans on natural landscapes, threats to biodiversity, methods and theories of conservation biology, environmental laws, and relevant economic…

Cd-Rom and Access to Information

OpenAIRE

Chacón Alvarado, Lucía

2011-01-01

The scientific and technological advances in the world and its application in different areas of knowledge have developed a new electronic age.Computers and telecommunications have created a new scenario for libraries and information centers leading to further changes in the use of its collections and its services increased. Libraries and information centers must address these changes because users demand access to information quickly and efficiently.The CD-ROM is a new technology that has be...

Data base management system and display software for the National Geophysical Data Center geomagnetic CD-ROM's

Science.gov (United States)

Papitashvili, N. E.; Papitashvili, V. O.; Allen, J. H.; Morris, L. D.

1995-01-01

The National Geophysical Data Center has the largest collection of geomagnetic data from the worldwide network of magnetic observatories. The data base management system and retrieval/display software have been developed for the archived geomagnetic data (annual means, monthly, daily, hourly, and 1-minute values) and placed on the center's CD-ROM's to provide users with 'user-oriented' and 'user-friendly' support. This system is described in this paper with a brief outline of provided options.

Effects of Using Human Patient Simulator (HPS versus a CD-ROM on Cognition and Critical Thinking

Directory of Open Access Journals (Sweden)

Don Johnson, PhD

2008-01-01

Full Text Available Background: Very little prospective randomized experimental research exists on the use of simulation as a teaching method, and no studies have compared the two strategies of using the HPS and a CD-ROM. In addition, no researchers have investigated the effects of simulation on various levels of cognition, specifically lower-level and higher-level cognition or critical thinking.Objectives: A prospective pretest-posttest experimental mixed design (within and between was used to determine if there were statistically significant differences in HPS and CD-ROM educational strategies in lower-level, higher-level cognition and critical thinking.Results: A repeated measures multivariate analysis of variance (RMANOVA with LSD post-hoc tests were used to analyze the data. There were no significant differences between the HPS and CD-ROM groups on lower-level cognition scores. The HPS group did significantly better than the CD-ROM group on higher-level cognition and critical thinking scores.Conclusion: This study demonstrated that the choice of teaching strategies for lower-level cognition does not make a statistically significant difference in outcome. However, the HPS is superior to using CD-ROM and should be considered as the choice in teaching.

CD ROM 'Natural heritage of Slovakia'

International Nuclear Information System (INIS)

Uradnikova, B.

2005-01-01

Centre of Environmental Education Geopark ('Centre') applied environmental education into school and out-of-school institutions. The 'Centre' is working in the fields: environmental education, eco-tourism development, presentation of the cultural landscape and world heritage. The CD ROM 'Natural heritage of Slovakia' was created with aim enhancement of environmental awareness, pedagogy, education and development of eco-tourism on the Slovakia. It abets general review about environment, its components, legislative, history and the present day of nature and landscape protection

A Look at Dialog's First CD-ROM Product.

Science.gov (United States)

Duggan, Mary Kay

1987-01-01

Discusses reasons for selecting ERIC with the Dialog OnDisc software for training information professionals in online searching at the University of California, Berkeley, and analyzes some of the features of the CD-ROM software. Pros and cons of online and OnDisc access are summarized, and three references are listed. (Author/MES)

Lab Manual & Resources for Materials Science, Engineering and Technology on CD-Rom

Science.gov (United States)

Jacobs, James A.; McKenney, Alfred E.

2001-01-01

The National Educators' Workshop (NEW:Update) series of workshops has been in existence since 1986. These annual workshops focus on technical updates and laboratory experiments for materials science, engineering and technology, involving new and traditional content in the field. Scores of educators and industrial and national laboratory personnel have contributed many useful experiments and demonstrations which were then published as NASA Conference Proceedings. This "out poring of riches" creates an ever-expanding shelf of valuable teaching tools for college, university, community college and advanced high school instruction. Now, more than 400 experiments and demonstrations, representing the first thirteen years of NEW:Updates have been selected and published on a CD-ROM, through the collaboration of this national network of materials educators, engineers, and scientists. The CD-ROM examined in this document utilizes the popular Adobe Acrobat Reader format and operates on most popular computer platforms. This presentation provides an overview of the second edition of Experiments in Materials Science, Engineering and Technology (EMSET2) CD-ROM, ISBN 0-13-030534-0.

The Market Place: An Internal View of the Future of CD-ROM--The Perspective of the H. W. Wilson Company.

Science.gov (United States)

Miller, Frank W.; Loeding, Deborah Voigt

1989-01-01

Discussion of technological developments in library reference services focuses on contributions of the H. W. Wilson Company and highlights CD-ROM technology. Topics discussed include online access; menu-driven systems; CD-ROM hardware and software concerns; user response to CD-ROM; quality control of databases; pricing considerations; and future…

The Writing Process for "Edutaining" CD-ROM Adventures.

Science.gov (United States)

Mountain, Lee

2000-01-01

Describes a CD-ROM adventure story written by the author to educate her students about the word relationships of synonyms and antonyms. Discusses how this interactive medium put a different twist on each of the stages of the writing process itself. Relates how two students enthusiastically used the program, and were inspired to write one of their…

Multimedia CD-Rom on hydrogen and fuel cells. 2. rev. ed.; Die Multimedia CD-Rom zum Thema Wasserstoff und Brennstoffzellen

Energy Technology Data Exchange (ETDEWEB)

Anon.

2007-07-01

This CD-Rom contains well-presented information with informative illustrations, as well as a large download section with publications, reports, and presentations in.pdf form for in-depth studies. There is also a list of links to selected websites, with short explanations. [German] Die CD zum Thema ''Wasserstoff und Brennstoffzellen'' bietet sowohl gut gegliederte Informationen mit anschaulichen Bildern fuer die Lektuere am Monitor als auch eine grosse Download-Rubrik, in der zahlreiche Publikationen, Fachberichte, Praesentationen als PDF-Dateien abgelegt sind und fuers Studium bereitstehen. Ausserdem gibt es ein Link-Verzeichnis mit Verweisen und Erlaeuterungen zu ausgewaehlten Internet-Seiten.

Land and Marine Gravity Data on CD-ROM - 1999 Edition

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — The Land and Marine Gravity 1999 Edition 2-volume CD-ROM set contains observed and derived land and marine gravity data contributed by many national and...

Whole Language, Computers and CD-ROM Technology: A Kindergarten Unit on "Benjamin Bunny."

Science.gov (United States)

Balajthy, Ernest

A kindergarten teacher, two preservice teachers, and a college consultant on educational computer technology designed and developed a 10-day whole-language integrated unit on the theme of Beatrix Potter's "Benjamin Bunny." The project was designed as a demonstration of the potential of integrating the CD-ROM-based version of…

Nanotechnology Aerospace Applications (Applications aerospatiales de la nanotechnologie) (CD-ROM)

National Research Council Canada - National Science Library

2007-01-01

...: 1 CD-ROM; 4 3/4 in.; 116 MB. ABSTRACT: The Educational Notes contain the abstracts and the lecture material of ten presentations, which provide a general introduction into nanotechnologies with selected topics, such as nanotechnology...

Nanotechnology Aerospace Applications (Applications aerospatiales de la nanotechnologie) (CD-ROM)

National Research Council Canada - National Science Library

2005-01-01

...: 1 CD-ROM; 4 3/4 in.; 59.1 MB. ABSTRACT: The Educational Notes contain the abstracts and the lecture material of ten presentations, which provide a general introduction into nanotechnologies with selected topics, such as nanotechnology...

Management of CD-ROM Resources in Nigeria Academic Libraries ...

African Journals Online (AJOL)

The study is on management of CD-ROM resources in Nigerian academic libraries with reference to Federal Polytechnic Nekede Library, Owerri. A descriptive survey method was adopted random sampling technique was used in selecting twenty five (25) staff from the library under study. The questionnaire was the major ...

Stretching & Flexibility: An Interactive Encyclopedia of Stretching. [CD-ROM].

Science.gov (United States)

2002

This CD-ROM offers 140 different stretches in full-motion video sequences. It focuses on the proper techniques for overall physical fitness, injury prevention and rehabilitation, and 23 different sports (e.g., golf, running, soccer, skiing, climbing, football, and baseball). Topics include stretching for sports; stretching awareness and education…

Guide Structures in CD-ROM Dic- tionaries, with Specific Reference ...

African Journals Online (AJOL)

Not all the search options in CD-ROM dictionaries necessarily maintain the boundaries ... In this article all derivatives of lase are highlighted in the microstructure, ... searches frustrates the user and should be addressed in future editions of the.

Public census data on CD-ROM at Lawrence Berkeley Laboratory. Revision 4

Energy Technology Data Exchange (ETDEWEB)

Merrill, D.W.

1993-03-12

The Comprehensive Epidemiologic Data Resource (CEDR) and Populations at Risk to Environmental Pollution (PAREP) projects, of the Information and Computing sciences Division (ICSD) at Lawrence Berkeley Laboratory (LBL), are using public socioeconomic and geographic data files which are available to CEDR and PAREP collaborators via LBL`s computing network. At this time 89 CD-ROM diskettes (approximately 45 gigabytes) are on line via the Unix file server cedrcd.lbl.gov. Most of the files are from the US Bureau of the Census, and many of these pertain to the 1990 Census of Population and Housing. All the CD-ROM diskettes contain documentation in the form of ASCII text files. In addition, printed documentation for most files is available for inspection at University of California Data and Technical Assistance (UC DATA), tel. (510) 642-6571, or the UC Documents Library, tel. (510) 642-2569, both located on the UC Berkeley Campus. Many of the CD-ROM diskettes distributed by the Census Bureau contain software for PC compatible computers, for easily accessing the data. Shared access to the data is maintained through a collaboration among the CEDR and PAREP projects at LBL, and UC DATA, and the UC Documents Library. LBL is grateful to UC DATA and the UC Documents Library for the use of their CD-ROM diskettes. Shared access to LBL facilities may be restricted in the future if costs become prohibitive. Via the Sun Network File System (NFS), these data can be exported to Internet computers for direct access by the user`s application program(s). Due to the size of the files, this access method is preferred over File Transfer Protocol (FTP) access.

Public census data on CD-ROM at Lawrence Berkeley Laboratory. Revision 1

Energy Technology Data Exchange (ETDEWEB)

Merrill, D.W.

1992-07-02

In connection with the Comprehensive Epidemiologic Data Resource (CEDR) and Populations at Risk to Environmental Pollution (PAREP) projects, of the Information and Computing Sciences Division (ICSD) at Lawrence Berkeley Laboratory (LBL), are using public socioeconomic and geographic data files which are available to CEDR and PAREP collaborators via LBL`s computing network. At this time 67 CD-ROM diskettes (approximately 35 gigabytes) are on line via the Unix file server cedrcd.lbl.gov. Most of the files are from the US Bureau of the Census, and most pertain to the 1990 Census of Population and Housing. This paper contains a list of the CD-ROMs available.

Effects of using simulation versus CD-ROM in the performance of ultrasound-guided regional anesthesia.

Science.gov (United States)

Gasko, John; Johnson, Arthur; Sherner, John; Craig, John; Gegel, Brian; Burgert, James; Sama, Samuel; Franzen, Thomas

2012-08-01

The purpose of this study was to determine which method of teaching, CD-ROM, simulation, or a combination of both, was more effective in increasing the performance of ultrasound-guided regional anesthesia. No studies have investigated these methods. The framework for this study was critical thinking. The study was a prospective, mixed (between and within) subjects, experimental design. The sample consisted of 29 student registered nurse anesthetists randomly assigned to 1 of 3 groups: CD-ROM (n = 11), simulation (n = 11), and combination (n = 7). All groups were evaluated by the use of cadavers before and 2 months after the intervention using a valid and reliable instrument of performance. A repeated-measures analysis of variance indicated that the combination was significantly better than the CD-ROM and simulation (P teaching ultrasound-guided regional anesthesia techniques.

CD-ROM for the PGAA-IAEA database

International Nuclear Information System (INIS)

Firestone, R.B.; Zerking, V.

2007-01-01

Both the database of prompt gamma rays from slow neutron capture for elemental analysis and the results of this CRP are available on the accompanying CD-ROM. The file index.html is the home page for the CD-ROM, and provides links to the following information: (a) The CRP - General information, papers and reports relevant to this CRP. (b) The PGAA-IAEA database viewer - An interactive program to display and search the PGAA database by isotope, energy or capture cross-section. (c) The Database of Prompt Gamma Rays from Slow Neutron Capture for Elemental Analysis - This report. (d) The PGAA database files - Adopted PGAA database and associated files in EXCEL, PDF and Text formats. The archival databases by Lone et al. and by Reedy and Frankle are also available. (e) The Evaluated Gamma-Ray Activation File (EGAF) - The adopted PGAA database in ENSDF format. Data can be viewed with the Isotope Explorer 2.2 ENSDF Viewer. (f) The PGAA database evaluation - ENSDF format versions of the adopted PGAA database, and the Budapest and ENSDF isotopic input files. Decay scheme balance and statistical analysis summaries are provided. (g) The Isotope Explorer 2.2 ENSDF viewer - Windows software for viewing the level scheme drawings and tables provided in ENSDF format. The complete ENSDF database is included, as of December 2002. The databases and viewers are discussed in greater detail in the following sections

Reservoir and civil engineering geophysics (CD-Rom); Geophysique de gisement et de genie civil (CD-Rom)

Energy Technology Data Exchange (ETDEWEB)

Mari, J.L.; Chapellier, D.

1999-07-01

This CD-Rom is a pedagogical tool developed from the book 'field and civil engineering geophysics' (Technip ed., 1998). It presents the geophysical methods (surface and well geophysical surveys, radar surveys and well logging) and their application in the study of oil fields and also in civil engineering. Several cartoons illustrate the principle of methods, their domain of use and their limitations. It covers the following topics: surface seismic surveys (waves propagation, equipments, reflexion and refraction seismic surveys, surface waves); well seismic surveys (operation, data processing, imaging); well logging (acoustic, nuclear,electrical and others, methods of interpretation); radar surveys (principle, surface, wells, possibilities and limitations). (J.S.)

Managing nuclear knowledge: IAEA activities and international coordination. Including resource material full text CD-ROM

International Nuclear Information System (INIS)

2005-06-01

The present CD-ROM summarizes some activities carried out by the Departments of Nuclear Energy and Nuclear Safety and Security in the area of nuclear knowledge management in the period 2003-2005. It comprises, as open resource, most of the relevant documents in full text, including policy level documents, reports, presentation material by Member States and meeting summaries. The collection starts with a reprint of the report to the IAEA General Conference 2004 on Nuclear Knowledge [GOV/2004/56-GC(48)/12] summarizing the developments in nuclear knowledge management since the 47th session of the General Conference in 2003 and covers Managing Nuclear Knowledge including safety issues and Information and Strengthening Education and Training for Capacity Building. It contains an excerpt on Nuclear Knowledge from the General Conference Resolution [GC(48)/RES/13] on Strengthening the Agency's Activities Related to Nuclear Science, Technology and Applications. On the CD-ROM itself, all documents can easily be accessed by clicking on their titles on the subject pages (also printed at the end of this Working Material). Part 1 of the CD-ROM covers the activities in the period 2003-2005 and part 2 presents a resource material full text CD-ROM on Managing Nuclear Knowledge issued in October 2003

Public census data on CD-ROM at Lawrence Berkeley Laboratory. Revision 3

Energy Technology Data Exchange (ETDEWEB)

Merrill, D.W.

1993-01-16

The Comprehensive Epidemiologic Data Resource (CEDR) and Populations at Risk to Environmental Pollution (PAREP) projects, of the Information and Computing Sciences Division (ICSD) at Lawrence Berkeley Laboratory (LBL), are using public socioeconomic and geographic data files which are available to CEDR and PAREP collaborators via LBL`s computing network. At this time 72 CD-ROM diskettes (approximately 37 gigabytes) are on line via the Unix file server ``cedrcd.lbl.gov``. Most of the files are from the US Bureau of the Census, and many of these pertain to the 1990 Census of Population and Housing. All the CD-ROM diskettes contain documentation in the form of ASCII text files. In addition, printed documentation for most files is available for inspection at University of California Data and Technical Assistance (UC DATA), tel. (510) 642-6571, or the UC Documents Library, tel. (510) 642-2569, both located on the UC Berkeley Campus. Many of the CD-ROM diskettes distributed by the Census Bureau contain software for PC compatible computers, for easily accessing the data. Shared access to the data is maintained through a collaboration among the CEDR and PAREP projects at LBL, and UC DATA, and the UC Documents Library. LBL is grateful to UC DATA and the UC Documents Library for the use of their CD-ROM diskettes. Shared access to LBL facilities may be restricted in the future if costs become prohibitive. Via the Sun Network File System (NFS), these data can be exported to Internet computers for direct access by the user`s application program(s). Due to the size of the files, this access method is preferred over File Transfer Protocol (FTP) access. Please contact Deane Merrill (dwmerrill@lbl.gov) if you wish to make use of the data.

Operating Experience with Nuclear Power Stations in Member States. 2016 Edition (CD-ROM)

International Nuclear Information System (INIS)

2016-06-01

This CD-ROM contains the 47th edition of the IAEA’s series of annual reports on operating experience with nuclear power plants in Member States. It is a direct output from the IAEA’s Power Reactor Information System (PRIS) and contains information on electricity production and overall performance of individual plants during 2015. In addition to annual information, the report contains a historical summary of performance during the lifetime of individual plants and figures illustrating worldwide performance of the nuclear industry. The CD-ROM contains also an overview of design characteristics and dashboards of all operating nuclear power plants worldwide

Investigating the use of CD-Rom CBT for bulimia nervosa and binge eating disorder in an NHS adult outpatient eating disorders service.

Science.gov (United States)

Graham, Lisa; Walton, Mark

2011-07-01

Many patients who experience bulimia nervosa (BN) and binge eating disorder (BED) find it hard to access evidence-based treatments. Rates of failure to enter outpatient services following initial assessment are high, as are dropout rates from specialist outpatient eating disorders services. To offer CD-Rom CBT, a cognitive-behavioural multi-media supported self-help treatment, in a locality-based outpatient NHS Eating Disorders Service to patients who have binge eating disorder and bulimia nervosa. Patients referred to a catchment-based NHS outpatient eating disorders service who were assessed and had an eating disorder with a binge-eating component were offered CD-Rom based CBT (Overcoming Bulimia) whilst on the waiting list for individual CBT. Forty patients completed the 8 sessions and attended the evaluation appointment (13 had BN, 27 had BED). For both groups, there were significant improvements in well-being and functioning, as well as significant reductions in problems and risk. There was also a significant reduction on the "Bulimic Subscale" of the EDI. These results were comparable with the original study findings (Schmidt, Treasure and Williams, 2001). Dropouts from the CD-Rom reflected rates common to other EDS treatments suggesting that CD-Rom did not directly impact upon service dropout rates. Computer assisted CBT for Eating Disorders offers a promising, feasible and acceptable first step for patients who have bulimia nervosa or binge eating disorder and access treatment from specialist eating disorders services.

Experience teaching CD-ROM-based course on CANDU nuclear-power-plant systems and operation

International Nuclear Information System (INIS)

Rouben, Benjamin

2008-01-01

This paper presents personal experience garnered from teaching a CD-ROM-based course on CANDU Power-Plant Systems and Operation. This course was originally developed by Prof. G.T. Bereznai as research in distance-learning techniques when he was directing the Thai-Canadian Human Resources Development Project at Chulalongkorn University in Bangkok. The course has been offered in a number of universities, including McMaster University and the University of Ontario Institute of Technology. All the course material, including lectures, assignments, and a simulator, is provided on a CD-ROM. Lectures include a spoken soundtrack covering the material. The class often includes both undergraduate and graduate students. I found that most students appreciate having the material on electronic format, which they can view and review at will and on their own time. Students find this course quite intensive - it covers all major systems in the CANDU reactor and power plant in detail. A very important component of the course is the simulator, which teaches students how systems operate in normal operation, in power manoeuvres, and during process-system malfunctions. Effort in absorbing the material and performing assignments can often exceed 10 hours per week. Some of the simulator assignments involve tricky manoeuvres, requiring several tries to achieve the expected result. Some assignments may take several hours, especially if the manoeuvres requiring repetition take 30 minutes or more in real time. I found that some instruction in the basic theory of reactor physics and systems is appreciated by students. A few possible enhancements to the simulator model were identified. Graduate students taking the course are required to do an additional project; I assigned an investigation of the effects of xenon-concentration changes during 1 week of load cycling. In summary, this course provides to students the opportunity to learn a great deal about the workings of CANDU-plant systems. (author)

NODC Standard Product: World Ocean Circulation Experiment (WOCE) Global Data Resource (GDR), versions 1-3, on CD-ROM and DVD

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — NODC produced twelve (12) CD-ROMs containing WOCE Version 1 project data in the summer of 1998. NODC produced fifteen (15) CD-ROMs containing WOCE Version 2 project...

Method for a dummy CD mirror server based on NAS

Science.gov (United States)

Tang, Muna; Pei, Jing

2002-09-01

With the development of computer network, information sharing is becoming the necessity in human life. The rapid development of CD-ROM and CD-ROM driver techniques makes it possible to issue large database online. After comparing many designs of dummy CD mirror database, which are the embodiment of a main product in CD-ROM database now and in near future, we proposed and realized a new PC based scheme. Our system has the following merits, such as, supporting all kinds of CD format; supporting many network protocol; the independence of mirror network server and the main server; low price, super large capacity, without the need of any special hardware. Preliminarily experiments have verified the validity of the proposed scheme. Encouraged by the promising application future, we are now preparing to put it into market. This paper discusses the design and implement of the CD-ROM server detailedly.

Canister Design for Deep Borehole Disposal of Nuclear Waste (CD-ROM)

National Research Council Canada - National Science Library

Hoag, Christopher I

2006-01-01

...: 1 CD-ROM; 4 3/4 in.; 28.7 MB. ABSTRACT: The objective of this thesis was to design a canister for the disposal of spent nuclear fuel and other high-level waste in deep borehole repositories using currently available and proven oil, gas...

Air Force Research Laboratorv Success Stories: A Review of 2004 (CD-ROM)

National Research Council Canada - National Science Library

2004-01-01

...). PHYSICAL DESCRIPTION: 1 CD-ROM; 4 3/4 in.; 43.5 MB. ABSTRACT: The Air Force Science and Technology Success Stories herein often represent the combined effort of several scientists and engineers working as a team...

Students' Attitudes toward ABI/INFORM on CD-ROM: A Factor Analysis.

Science.gov (United States)

Wang, Vicky; Lau, Shuk-fong

Two years after the introduction of CD-ROM bibliographic database searching in the Memphis State University libraries (Tennessee), a survey was conducted to examine students' attitudes toward the business database, ABI/INFORM. ABI/INFORM contains indexes and abstracts of articles from over 800 journals on management, accounting, banking, human…

Energy-Smart Choices for Schools. An HVAC Comparison Tool. [CD-ROM].

Science.gov (United States)

Geothermal Heat Pump Consortium, Inc., Washington, DC.

A CD ROM program provides comparison construction cost capabilities for heating, ventilation, and air conditioning (HVAC) systems in educational facilities. The program combines multiple types of systems with square footage data on low and high construction cost and school size to automatically calculate HVAC comparative construction costs. (GR)

In Praise of Mr. S. Platter and His Marvelous, Magnificent CD ROM Laser Disc Index for ERIC and PSYCHLIT.

Science.gov (United States)

Huffman, Robert F.

These instructions are designed to help patrons of the University of Missouri-Columbia library perform searches on PSYCHLIT, a CD-ROM (compact disc, read only memory) version of the Psych Abstracts database, and a CD-ROM version of the ERIC database, both produced by SilverPlatter Information Services. Basic information is provided about the disk…

Operating Experience with Nuclear Power Stations in Member States in 2014. 2015 Edition (CD-ROM)

International Nuclear Information System (INIS)

2015-01-01

This CD-ROM contains the 46th edition of the IAEA’s series of annual reports on operating experience with nuclear power plants in Member States. It is a direct output from the IAEA’s Power Reactor Information System (PRIS) and contains information on electricity production and overall performance of individual plants during 2014. In addition to annual information, the report contains a historical summary of performance during the lifetime of individual plants and figures illustrating worldwide performance of the nuclear industry. The CD-ROM contains also an overview of design characteristics and dashboards of all operating nuclear power plants worldwide

CD-ROM training course in quality assurance in diagnostic imaging

International Nuclear Information System (INIS)

Khoury, H.J.; Machado, P.; Drexler, G.

2001-01-01

This paper discusses the CD-ROM elaborated to provide a continuous professional formation and a practical guidance on the implementation and operation of routine quality assurance (QA) programme for medical physicists, regulator authorities and for those personnel concerned with the daily provision of diagnostic radiology services. The CD-ROM contains topics on the basic concepts of QA in radiodiagnostic, and it also allows the user to visualise effects on the variation of technical parameters (tube potential (kV) and current (mA), filtration) in the quality of the image. This possibility will contribute to the better understanding of the phenomena associated with the quality of the image. Besides, the program contains the procedures for the execution of the tests of the equipment and the route of implantation of program of quality assurance. It is interactive with the user, it fills a gap in the medical physics area and it allows the student's continuous formation because it assists the beginner, with the basic concepts, and the professional, with the aid in the implantation of the program of QA. The presentation is in the Portuguese language. (author)

經由校園網路存取圖書館光碟資料庫之研究 Studies on Multiuser Access Library CD-ROM Database via Campus Network

Directory of Open Access Journals (Sweden)

Ruey-shun Chen

1992-06-01

Full Text Available 無Library CD-ROM with its enormous storage, retrieval capabilities and reasonable price. It has been gradually replacing some of its printed counterpart. But one of the greatest limitation on the use of stand-alone CD-ROM workstation is that only one user can access the CD-ROM database at a time. This paper is proposed a new method to solve this problem. The method use personal computer via standard network system Ethernet high speed fiber network FADDY and standard protocol TCP/IP can access library CD-ROM database and perform a practical CD-ROM campus network system. Its advantage reduce redundant CD-ROM purchase fee and reduce damage by handed in and out and allows multiuser to access the same CD-ROM disc simultaneously.

Operating Experience with Nuclear Power Stations in Member States in 2013. 2014 Edition (CD-ROM)

International Nuclear Information System (INIS)

2014-07-01

This CD-ROM contains the 45th edition of the IAEA's series of annual reports on operating experience with nuclear power plants in Member States. It is a direct output from the IAEA's Power Reactor Information System (PRIS) and contains information on electricity production and overall performance of individual plants during 2013. In addition to annual information, the report contains a historical summary of performance during the lifetime of individual plants and figures illustrating worldwide performance of the nuclear industry. The CD-ROM contains also an overview of design characteristics and dashboards (not included into the web version) of all operating nuclear power plants worldwide

Car Builder: Design, Construct and Test Your Own Cars. School Version with Lesson Plans. [CD-ROM].

Science.gov (United States)

Highsmith, Joni Bitman

Car Builder is a scientific CD-ROM-based simulation program that lets students design, construct, modify, test, and compare their own cars. Students can design sedans, four-wheel-drive vehicles, vans, sport cars, and hot rods. They may select for aerodynamics, power, and racing ability, or economic and fuel efficiency. It is a program that teaches…

The New York Trade Publishers and CD-ROM: Where Are They Heading?

Science.gov (United States)

Newmark, Eileen

1994-01-01

Discusses the strategies top trade publishers, including Putnam New Media, Paramount Communications, Random House, Penguin USA, and Reader's Digest, are taking toward CD-ROM publishing. Strategies include purchasing electronic media companies; setting up an independent business; and building a new media business by integrating new efforts into the…

Factors Affecting Pre-Service TESOL Teachers' Attitudes towards Using CD-ROM Dictionary

Science.gov (United States)

Issa, Jinan Hatem; Jamil, Hazri

2011-01-01

Rapid technological advances in communication technologies and computational power are altering the nature of knowledge, skills, talents and the know-how of individuals. A CD-ROM dictionary is an interesting and effective teaching tool, which captures pre-service teachers' interest and does much more than just translates especially with the…

In company pre-intermediate student's book with CD-ROM

CERN Document Server

Clarke, Simon; Sharma, Pete

2009-01-01

In Company has established itself as the Business English course for professionals because of its immediate results through topic-based content, active skills, and real-world tasks that are instantly relevant to everyday business English development. In Company Second Edition builds on the success of the original but is now updated and improved with a host of new features. For extra online practice for your students, take a look at the new Second Edition In Company Practice Online solution. Accompanying the popular In Company series in British English, these online courses provide carefully designed resources to supplement the Student's Books at all levels. Units are clearly defined as Topic or Skills based NEW phrase banks with useful phrases for reference and revision 5 NEW case studies, within the Student's Book reflect real-life business scenarios Second Edition CD-ROM now includes a new interactive glossary and the class audio as a donwloadable MP3.

Guide Structures in CD-ROM Dictionaries, with Specific Reference to the EWED and the ELHAT

Directory of Open Access Journals (Sweden)

Philip Louw

2011-10-01

Full Text Available

macro- and microstructural information. In order to evaluate the methods which lexicographers employ to improve dictionary accessibility, the concept of guide structures was introduced by Hausmann and Wiegand (1989. Since the appearance of that article, various academics have written articles and read papers on guide structures in print dictionaries, but few studies have focussed on the tremendous potential of guide structures in electronic dictionaries. In this article it will be shown that electronic dictionaries add dimensions to the implementation of guide structures not possible in print versions. The role of two of the guide structures in the transfer of infonnation in CD-ROM dictionaries will be discussed. The access and mediostructures of the Microsoft Encarta World English Dictionary and the Elektroniese Handwoordeboek van die Afrikaanse Taal will be analysed and critically evaluated to illustrate the advantages of electronic dictionaries over print dictionaries and the urgent need for metalexicographical discussion of this publication medium.

Keywords: ACCESS STRUCTURE; ACTIVE CROSS-REFERENCES; CD-ROM DICTIONARY; DICTIONARY ACCESSIBILITY; ENCYCLOPAEDIC DICTIONARY; GUIDE STRUCTURES; INNER ACCESS STRUCTURE; INNER SEARCH PATH; INTERNET; MEDIOSTRUCTURE; MULTIMEDIA; OUTER ACCESS STRUCTURE; OUTER SEARCH PATH; PASSIVE CROSSREFERENCING; USER-FRIENDLINESS

Opsomming: Gidsstrukture in CD-ROM-woordeboeke, met spesifieke verwysingna EWED en ELHA T. Die sukses van modeme woordeboeke hang grootliles af vandie toeganklikheid van hulle makro- en mikrostrukturele inligting. Hausmann en Wiegand (1989het die konsep van gidsstrukture ingevoer om die metodes te evalueer wat leksikograwe gebruikom woordeboektoeganklikheid Ie verbeter. Sedert hierdie artikel verskyn het, het verskeie akademic:i artikels gepubliseer en referate gelewer oor gidsstrukture in gedrukte woordeboeke, maarmin studies het gefokus op die geweldige potensiaal van

Advanced grammar in use a self-study reference and practice book for advanced students of English : with answers and CD-ROM

CERN Document Server

Hewings, Martin

2013-01-01

An updated version of the highly successful Advanced Grammar in Use. This third edition, with answers and CD-ROM, is ideal for self-study. The book contains 100 units of grammar reference and practice materials, with illustrations in full colour and a user-friendly layout. It is ideal for learners preparing for the Cambridge Advanced, Proficiency or IELTS examinations, and is informed by the Cambridge International Corpus, which ensures the language is authentic and up-to-date. The CD-ROM includes 200 interactive exercises to reinforce the language learned in the book, plus customised tests and audio recordings to accompany the main exercises. Versions without answers and without the CD-ROM are available to purchase separately.

Occupational Analysis Products: Space Systems Operations - AFSC 1C6X1 (CD-ROM)

National Research Council Canada - National Science Library

Boerstler, Robert E

2004-01-01

...: 1 CD-ROM; 4 3/4 in.; 30.4 MB. SYSTEMS DETAIL NOTE: ABSTRACT: The Space Systems Operations career ladder was surveyed to obtain current task and equipment data for use in evaluating current training programs...

Analysis of User Need with CD-ROM Databases: A Case Study Based on Work Sampling at One University Library.

Science.gov (United States)

Wells, Amy Tracy

Analysis of the needs of users of Compact Disk-Read Only Memory (CD-ROM) was performed at the Tampa campus of the University of South Florida. A review of the literature indicated that problems associated with selecting the appropriate database, searching, and requiring technical assistance were the probable areas of user need. The library has 17…

Caspian Sea Energy: Oil, Politics and Development in the Caspian Sea Region (CD-ROM)

National Research Council Canada - National Science Library

Light, Chris

2004-01-01

...: 1 CD-ROM; 4 3/4 in.; 5.0 MB. ABSTRACT: The purpose of this paper is to present the major issues impacting Caspian hydrocarbon development Specifically, a number of topics including the regions geography, history, governments, politics...

Year 5 Pupils Reading an "Interactive Storybook" on CD-ROM: Losing the Plot?

Science.gov (United States)

Trushell, John; Burrell, Clare; Maitland, Amanda

2001-01-01

This study examined whether small groups of grade 5 students in a London primary school, without teacher supervision, progressed linearly through an interactive storybook on CD-ROM, and whether such diversions as cued animations affected pupil comprehension. Results showed students' recall of the storyline was poor. (Author/LRW)

Setting Up CD-ROM Work Areas. Part I: Ergonomic Considerations, User Furniture, Location.

Science.gov (United States)

Vasi, John; LaGuardia, Cheryl

1992-01-01

The first of a two-part series on design of CD-ROM work areas in libraries discusses (1) space and location considerations; (2) ergonomics, including work surface, chairs, lighting, printers, other accessories, and security; and (3) other considerations, including staff assistance, reference tools, literature racks, and promotional materials. (MES)

Helping Family Physicians Improve Their Cardiac Auscultation Skills with an Interactive CD-ROM.

Science.gov (United States)

Roy, Douglas; Sargeant, Joan; Gray, Jean; Hoyt, Brian; Allen, Michael; Fleming, Michael

2002-01-01

Physicians (n=42) studied cardiac auscultation using a 15-hour CD-ROM program. Nine months later, 21 who completed a posttest showed significant improvement in identifying heart sounds. CDs were valued for opportunities to review material at an individual pace. Lack of computer skills hindered use. (Contains 26 references.) (SK)

How To Use the SilverPlatter Software To Search the ERIC CD ROM.

Science.gov (United States)

Merrill, Paul F.

This manual provides detailed instructions for using SilverPlatter software to search the ERIC CD ROM (Compact Disk Read Only Memory), a large bibliographic database relating to education which contains reference information on numerous journal articles from over 750 journals cited in the "Current Index to Journals in Education" (CIJE),…

Occupational Analysis Products: Operations Management- AFSC 3E6X1 (CD-ROM)

Science.gov (United States)

computer laser optical disc (CD-ROM); 4 3/4 in.; 23.4 MB. SYSTEMS DETAIL NOTE: ABSTRACT: This is a report of an occupational survey of the Operations ... Management (AFSC 3E6X1, OSSN 2560, Feb 04) career ladder, conducted by the Occupational Analysis Flight, AFOMS. The OSR reports the findings of current

Evaluation of the use of CD-ROM upload into the PACS or institutional web server

NARCIS (Netherlands)

van Ooijen, P. M. A.; Roosjen, R.; de Blecourt, M. J.; van Dam, R.; Broekema, A.; Oudkerk, M.

2006-01-01

Purpose: Patient data are increasingly distributed between hospitals using CD-ROMs instead of actual films. This introduces problems because different viewers from different vendors are provided, and sometimes viewers are unusable because local software installation is not allowed. In 2004, we

DICOM storage into PACS of out-hospital CD-ROMs - a half year experience report

NARCIS (Netherlands)

van Ooijen, PMA; ten Bhomer, PJM; Blecourt, MJ; Roosjen, R; van Dam, R; Oudkerk, A; Lemke, HU; Inamura, K; Doi, K; Vannier, MW; Farman, AG

2005-01-01

With the advance of digitalization of radiology departments, the interchange of data between institutions is shifting towards shipment of CD-ROMs instead of physical film. Although this is a positive change in terms of costs, it also has its downsides. One of the main problems is how to integrate

Recovery of Data from the Narragansett Bay Project, 1985-1992: User's Manual and CD-ROM

Science.gov (United States)

Data from the 1985-1992 era of the Narragansett Bay Project, an estuary of the National Estuary Program, were recovered from numerous storage media, updated to modern software, and burned to CD-ROM. The data will be used by, among others, EPA researchers working on long-term tren...

Exploiting the Potential of CD-ROM Databases: Staff Induction at the University of East Anglia.

Science.gov (United States)

Guillot, Marie-Noelle; Kenning, Marie-Madeleine

1995-01-01

Overviews a project exploring the possibility of using CD-ROM applications and the design of exploratory didactic materials to introduce academic staff to the field of computer-assisted instruction. The project heightened the staff's awareness of electronic resources and their potential as research, teaching, and learning aids, with particular…

Flight Experiments for Hypersonic Vehicle Development (Experimentations envol pour le developpement d'un vehicule hypersonique) (CD-ROM)

National Research Council Canada - National Science Library

2007-01-01

...: 1 CD-ROM; 4 3/4 in.; 124 MB. ABSTRACT: This RTO-AVT/VKI Lecture Series brought together specialists from Europe, USA, and Russia to discuss flight experiments that pertain to the development of hypersonic vehicles...

The Impact of Animation in CD-ROM Books on Students' Reading Behaviors and Comprehension.

Science.gov (United States)

Okolo, Cindy; Hayes, Renee

This study evaluated the use of children's literature presented via one of three conditions: an adult reading a book to the child; the child reading a CD-ROM version of a book on the computer but without animation; and the child reading the book on the computer with high levels of animation. The study, in one primary grade classroom, involved 10…

[Medical knowledge in immunological security of red blood cells transfusion in Tunisia: evaluation of a CD-ROM of auto-learning].

Science.gov (United States)

Ben Salah, N; El Borgi, W; Aounallah Skhiri, H; Ben Lakhal, F; Mouelhi, H; Zoueri, B; Gouider, E; Hafsia, R

2013-09-01

In Tunisia, red blood cells (RBC) transfusion joins in a statutory frame but remains subject to failures because of the misunderstanding of legislation and regulations. Our purpose is to estimate the knowledge of the medical staff in the immunological safety of RBC transfusion before and after reading an auto-education CD-ROM. It is a study of evaluation of an intervention. Eighty physicians participated to the study. The evaluation was done using an anonymous questionnaire, containing seven questions with multiple choices (QMC) relating to several items. The rate of good answers (RGA) calculated by questions and by items took into account the impact of the CD-ROM on the improvement of the answers after reading. The global average mark is 2.9/7. The RGA to questions varies from 22.5 % to 76.3%. All participants answered correctly to more than 50% of all items. Two answered correctly to all items. Among the participants, 31.3% answered to all "important" items, concerning ABO blood groups compatibility and ultimate bedside test. The rate of participation to the final evaluation was 83%. The impact of the CD-ROM was important and statistically significant. In the final evaluation, the global mark raised from 2.9 to 5.8/7, 31.5% (vs 2%) answered correctly all the questions and 95.5% (vs 31.3%) answered correctly all "important" items. This study revealed a misunderstanding of the doctors in immunological safety of RBC transfusions. Auto-teaching by CD-ROM was efficient. An improvement of the knowledge by continuous training is necessary in our country. Copyright © 2013 Elsevier Masson SAS. All rights reserved.

Defense Information for All: DTIC 2007 Conference Held in Alexandria, Virginia on March 26-28, 2007 (CD-ROM)

National Research Council Canada - National Science Library

2007-01-01

...: 1 CD-ROM; 4 3/4 in.; 88.6 MB. ABSTRACT: The conference will bring together information professionals from the science, technology, research and development, and acquisition communities who create, disseminate and use DoD scientific...

Analysis of Users' Searches of CD-ROM Databases in the National and University Library in Zagreb.

Science.gov (United States)

Jokic, Maja

1997-01-01

Investigates the search behavior of CD-ROM database users in Zagreb (Croatia) libraries: one group needed a minimum of technical assistance, and the other was completely independent. Highlights include the use of questionnaires and transaction log analysis and the need for end-user education. The questionnaire and definitions of search process…

The Lunar Source Disk: Old Lunar Datasets on a New CD-ROM

Science.gov (United States)

Hiesinger, H.

1998-01-01

A compilation of previously published datasets on CD-ROM is presented. This Lunar Source Disk is intended to be a first step in the improvement/expansion of the Lunar Consortium Disk, in order to create an "image-cube"-like data pool that can be easily accessed and might be useful for a variety of future lunar investigations. All datasets were transformed to a standard map projection that allows direct comparison of different types of information on a pixel-by pixel basis. Lunar observations have a long history and have been important to mankind for centuries, notably since the work of Plutarch and Galileo. As a consequence of centuries of lunar investigations, knowledge of the characteristics and properties of the Moon has accumulated over time. However, a side effect of this accumulation is that it has become more and more complicated for scientists to review all the datasets obtained through different techniques, to interpret them properly, to recognize their weaknesses and strengths in detail, and to combine them synoptically in geologic interpretations. Such synoptic geologic interpretations are crucial for the study of planetary bodies through remote-sensing data in order to avoid misinterpretation. In addition, many of the modem datasets, derived from Earth-based telescopes as well as from spacecraft missions, are acquired at different geometric and radiometric conditions. These differences make it challenging to compare or combine datasets directly or to extract information from different datasets on a pixel-by-pixel basis. Also, as there is no convention for the presentation of lunar datasets, different authors choose different map projections, depending on the location of the investigated areas and their personal interests. Insufficient or incomplete information on the map parameters used by different authors further complicates the reprojection of these datasets to a standard geometry. The goal of our efforts was to transfer previously published lunar

Mars Navigator: An Interactive Multimedia Program about Mars, Aerospace Engineering, Astronomy, and the JPL Mars Missions. [CD-ROM

Science.gov (United States)

Gramoll, Kurt

This CD-ROM introduces basic astronomy and aerospace engineering by examining the Jet Propulsion Laboratory's (JPL) Mars Pathfinder and Mars Global Surveyor missions to Mars. It contains numerous animations and narrations in addition to detailed graphics and text. Six interactive laboratories are included to help understand topics such as the…

Diffusivity database (DDB) system for major rocks (Version of 2006/specification and CD-ROM)

International Nuclear Information System (INIS)

Tochigi, Yoshikatsu; Sasamoto, Hirosi; Shibata, Masahiro; Sato, Haruo; Yui, Mikazu

2006-03-01

The development of the database system has been started to manage with the generally used. The database system has been constructed based on datasheets of the effective diffusion coefficient of the nuclides in the rock matrix in order to be applied on the 'H12: Project to Establish the Scientific and Technical Basis for HLW Disposal in Japan'. In this document, the examination and expansion of the datasheet structure and the process of construction of the database system and conversion of all data existing on datasheets are described. As the first step of the development of the database, this database system and its data will continue to be updated and the interface will be revised to improve the availability. The developed database system is attached on the CD-ROM as the file format of Microsoft Access. (author)

Nuclides 2000: an electronic chart of the nuclides on CD-ROM

International Nuclear Information System (INIS)

Magill, J.

2000-01-01

The 'Nuclides 2000' software package is an electronic chart of the nuclides, available on CD-ROM for Microsoft Windows operating systems, which offers extensive basic information on physics and radiology of the familiar nuclides. Moreover, 'Nuclides 2000' contains codes for a number of applications which allow the required data to be computed quickly and reliably by means of interactive user guidance. The data and codes are supplemented by information in the format of contributions on the history of radioactivity and radiochemistry, and on subjects of interest in physics, such as C-14 dating and the generation of Ti-44 in a supernova, and by a link collection of Internet addresses. As a detailed database, 'Nuclides 2000' can be used for teaching, research, and for practical applications. (orig.) [de

History, Development and Future of TRIGA Research Reactors. Companion CD-ROM

International Nuclear Information System (INIS)

2016-01-01

Due to its particular fuel design and resulting enhanced inherent safety features, TRIGA reactors (Training, Research, Isotopes, General Atomics) constitute a ‘class of their own’ among the large variety of research reactors built world-wide. This publication summarizes in a single document the information on the past and present of TRIGA research reactors and presents an outlook in view of potential issues to be solved by TRIGA operating organizations in the near future. It covers the historical development and basic TRIGA characteristics, followed by utilization, fuel conversion and ageing management of TRIGA research reactors. It continues with issues and challenges, introduction to the global TRIGA research reactor network and concludes with future perspectives. This CD-ROM illustrates the historical developments of TRIGA research reactors through individual facility examples and experiences

Effects of the CD-Rom Version of the "Self-Advocacy Strategy" on Quality of Contributions in IEP Meetings of High School Students with Intellectual Disability

Science.gov (United States)

Cease-Cook, Jennifer; Test, David W.; Scroggins, La' Shawndra

2013-01-01

This study used a multiple-probe across participants design to examine the effects of the CD-Rom version of the "Self-Advocacy Strategy" on quality of contributions in Individual Education Plan (IEP) meetings of five high school students with intellectual disability. Results indicated a functional relationship between using the CD-Rom…

Review of World of Money CD-ROM for PC/Mac [CD-ROM

Directory of Open Access Journals (Sweden)

Philip de Jersey

1998-12-01

Full Text Available Following on from the impressive development of the new HSBC Money Gallery in 1997, the British Museum has launched into the world of electronic publishing with the World of Money, an "interactive exploration of money worldwide from ancient times to the present day". Intended for ages ten to adult, the CD promises "a mine of information about the use, form, history and importance of money around the globe", and "fun and information for all the family". Reviewing in a Mac-unfriendly environment, I have been able to run the CD only on a PC. On a 166Mhz MMX with 32Mb RAM and a 12x CD it runs impressively quickly, with no more than two or three seconds of the "loading new page" display when switching between different parts of the program. Minimum requirements are listed as a 486 with 8Mb RAM, 40Mb free hard disk space, Windows 3.11 or Windows 95, 4x CD drive, 1Mb 256 colours graphics card, 16-bit Sound Blaster compatible sound card, and a VGA monitor. Minimum requirements for the Mac are listed as System 7, 603e processor, 16Mb RAM, 40MB free hard disk space, 6x CD drive, 1Mb video card and Apple monitor or Multisync with adaptor. The CD opens with an image of the British Museum portico, through which we are taken into the foyer, complete with the sound effects of massed ranks of tourists. We have four options available on a lectern, or by turning left, right or going upstairs: History of Money, Information Centre, Activities, and Options. Clicking on a large question mark brings up the Help screens (Figure 1.

Proceedings of the High Performance Embedded Computing Workshop (HPEC 2006) (10th). Held in Lexington, Massachusetts on September 19-21, 2006 (CD-ROM)

National Research Council Canada - National Science Library

Kepner, Jeremy

2007-01-01

...: 1 CD-ROM; 4 3/4 in.; 78.3 MB. ABSTRACT: The High-Performance Embedded Computing (HPEC) technical committee announced the tenth annual HPEC Workshop held in September 2006 at MIT Lincoln Laboratory in Lexington, MA...

School Survey on Crime and Safety (SSOCS) 2000 Public-Use Data Files, User's Manual, and Detailed Data Documentation. [CD-ROM].

Science.gov (United States)

National Center for Education Statistics (ED), Washington, DC.

This CD-ROM contains the raw, public-use data from the 2000 School Survey on Crime and Safety (SSOCS) along with a User's Manual and Detailed Data Documentation. The data are provided in SAS, SPSS, STATA, and ASCII formats. The User's Manual and the Detailed Data Documentation are provided as .pdf files. (Author)

FPGA Based Low Power ROM Design Using Capacitance Scaling

DEFF Research Database (Denmark)

Bansal, Meenakshi; Bansal, Neha; Saini, Rishita

2015-01-01

An ideal capacitor will not dissipate any power, but a real capacitor wil l have some power dissipation. In this work, we are going to design capacitance scaling based low power ROM design. In order to test the compatibility of this ROM design with latest i7 Processor, we are operating this ROM w...... in I/O Power, saving of 0.2% occur in Leakage Power, there will be a saving of 11.54% occur in Total Power. This design is implemented on Virtex-5 FPGA using Xilinx ISE and Verilog....

Quality Management Audits in Nuclear Medicine Practices. 2. Ed. Companion CD-ROM

International Nuclear Information System (INIS)

2015-01-01

Quality management systems are essential and should be maintained with the intent to continuously improve effectiveness and efficiency, enabling nuclear medicine to achieve the expectations of its quality policy, satisfy its customers and improve professionalism. The quality management (QM) audit methodology in nuclear medicine practice, introduced in this publication, is designed to be applied to a variety of economic circumstances. A key outcome is a culture of reviewing all processes of the clinical service for continuous improvement in nuclear medicine practice. Regular quality audits and assessments are vital for modern nuclear medicine services. More importantly, the entire QM and audit process has to be systematic, patient oriented and outcome based. The management of services should also take into account the diversity of nuclear medicine services around the world and multidisciplinary contributions. The latter include clinical, technical, radiopharmaceutical, medical physics and radiation safety procedures. This companion CD-ROM is attached to the printed STI/PUB/1683 and contains the full-text of STI/PUB/1683 as well as checklists in PDF and Excel format and a table with the contents of a standardized audit report

Effects of Contract Delivery Method on the LEED(trademark) Score of U.S. Navy Military Construction Projects (Fiscal Years 2004-2006) (CD-ROM)

National Research Council Canada - National Science Library

Carpenter, Deanna S

2005-01-01

...: 1 CD-ROM; 4 3/4 in.; 484 KB. ABSTRACT: This research study focused on determining the effects that the two major contract delivery methods had on the LEED score of projects over the design and construction time horizon...

NODC Standard Product: Coastal Change Analysis Program (C-CAP) Chesapeake Bay Region Data from 1984 to 1989 on CD-ROM (NODC Accession 9200303)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — The data set on this CD-ROM shows changes in land cover for the Chesapeake Bay region over the 5-year interval from 1984 to 1988-89. The data set was produced...

The use of U.S. Geological Survey CD-ROM-based petroleum assessments in undergraduate geology laboratories

Science.gov (United States)

Eves, R.L.; Davis, L.E.; Dyman, T.S.; Takahashi, K.I.

2002-01-01

Domestic oil production is declining and United States reliance on imported oil is increasing. America will be faced with difficult decisions that address the strategic, economic, and political consequences of its energy resources shortage. The geologically literate under-graduate student needs to be aware of current and future United States energy issues. The U.S. Geological Survey periodically provides energy assessment data via digitally-formatted CD-ROM publications. These publications are free to the public, and are well suited for use in undergraduate geology curricula. The U.S. Geological Survey (USGS) 1995 National Assessment of United States Oil and Gas Resources (Digital Data Series or DDS-30) (Gautier and others, 1996) is an excellent resource for introducing students to the strategies of hydrocarbon exploration and for developing skills in problem-solving and evaluating real data. This paper introduces the reader to DDS-30, summarizes the essential terminology and methodology of hydrocarbon assessment, and offers examples of exercises or questions that might be used in the introductory classroom. The USGS contact point for obtaining DDS-30 and other digital assessment volumes is also provided. Completing the sample exercises in this report requires a copy of DDS-30.

The use of CD-ROMs for storage and document delivery at the British Library Document Supply Centre

International Nuclear Information System (INIS)

Bradbury, D.

1990-05-01

The British Library Document Supply Centre (BLDSC) has been in the forefront of international document delivery for 20 years. During the last 5 years it has been very actively involved in the ADONIS Project, through which the full text of some 200 journals in the life sciences have been stored, accessed, and delivered through the medium of CD-ROM. The BLDSC's involvement in this project is described and indications of the lessons learned and of the implications for international document delivery systems in the future are given. (author)

The use of CD-ROMs for storage and document delivery at the British Library Document Supply Centre

Energy Technology Data Exchange (ETDEWEB)

Bradbury, D [British Library Document Supply Centre, Boston SPA (United Kingdom)

1990-05-01

The British Library Document Supply Centre (BLDSC) has been in the forefront of international document delivery for 20 years. During the last 5 years it has been very actively involved in the ADONIS Project, through which the full text of some 200 journals in the life sciences have been stored, accessed, and delivered through the medium of CD-ROM. The BLDSC`s involvement in this project is described and indications of the lessons learned and of the implications for international document delivery systems in the future are given. (author).

Students' and teachers' perceptions of motivation and learning through the use in schools of multimedia encyclopaedias on CD-ROM

OpenAIRE

Wishart , Jocelyn

2000-01-01

This article is the result of interviews with teachers, students, and school librarians in eight UK secondary schools regarding their use of multimedia encyclopaedias on CD-ROM. It focuses on a content analysis of their comments on how having access to multimedia encyclopaedias changes the way students work and learn in school, how they perceive it enhances their learning, and how it hinders it. Teachers reported that they used multimedia encyclopaedias as an additional information resource, ...

On-line vs DC-ROM delivery of information

NARCIS (Netherlands)

Waaijers, L.

1992-01-01

Considers the use of new technologies in library information delivery systems. Discusses the virtues of paper, CD-ROM, and online media in terms of accessibility, timeliness, compactness, searchability, preservability, authenticity, and appearance, as well as end user benefit. Surmises that

Review of The Earl of Abergavenny. Historical Record and Wreck Excavation CD-Rom

Directory of Open Access Journals (Sweden)

David Petts

2003-06-01

Full Text Available In early February 1805 a small fleet of East Indiamen accompanied by the frigate Weymouth set sail from Portsmouth heading first for Bengal and ultimately for China. However, barely had the voyage began when, following bad weather and confusion, one of the boats, the Earl of Abergavenny, struck the Shambles bank just off Portland Bill. Although the crew managed to free it, it was so badly damaged it sank while trying to make for the safety of Weymouth. Over 250 crew and passengers drowned. The wreck has until now been best known for causing the death of John Wordsworth, the ship's commander and brother of the poet William Wordsworth. This excellent CD report of archaeological investigations on the wreck site carried out since 1980 by the Weymouth Underwater Archaeological Group (WUAG brings us the full picture of the events leading up to the wreck, and a record of the remains found by the team of divers (Fig.1. The complex campaigns of diving have been carried out alongside extensive documentary and historical work. The huge amount of data created by this project has inevitably led to challenges for the WUAG regarding its publication (Cumming 2002. The decision to publish via a CD-ROM has allowed very large quantities of data and discussion to be published. The current version of the CD contains over 100,000 words of text, 1560 files and over 1000 illustrations (JPEGS. All for the grand price of 10 GBP. The volume can be browsed using a commercially available browser but is also supplied as compiled file using Web Compiler, which has the advantage of a search facility.

Processing of Irradiated Graphite to Meet Acceptance Criteria for Waste Disposal. Results of a Coordinated Research Project. Companion CD-ROM

International Nuclear Information System (INIS)

2016-05-01

Graphite is widely used in the nuclear industry and in research facilities and this has led to increasing amounts of irradiated graphite residing in temporary storage facilities pending disposal. This publication arises from a coordinated research project (CRP) on the processing of irradiated graphite to meet acceptance criteria for waste disposal. It presents the findings of the CRP, the general conclusions and recommendations. The topics covered include, graphite management issues, characterization of irradiated graphite, processing and treatment, immobilization and disposal. Included on the attached CD-ROM are formal reports from the participants

Technical and Scientific Support Organizations Providing Support to Regulatory Functions. Companion CD-ROM

International Nuclear Information System (INIS)

2018-01-01

This publication introduces the general principles underlying the provision of technical and scientific support to a regulatory body and the characteristics of organizations providing such support. It describes the services provided to support regulatory functions as well as the associated activities and processes to maintain the needed level of expertise, state of the art tools and equipment. The publication is intended for use primarily by organizations that provide technical and scientific support in the field of nuclear and radiation safety. This also includes organizations that acquire such support, and regulatory bodies and governments, as they make decisions on the model of technical and scientific support to be developed at the national level, for example in the case of a country embarking on the development of a nuclear power programme. It is the first IAEA publication dedicated to the specific practices and challenges to be met by the technical and scientific support organizations. This CD-ROM includes the annexes to the printed publication of examples of TSOs and their interactions with key stakeholders.

Ionospheric Electron/Ion Densities Temperatures on CD-ROM and WWW

Science.gov (United States)

Bilitza, Dieter; Papitashvili, Natasha; Schar, Bill; Grebowsky, Joseph

2002-01-01

As part of this project a large volume of ionospheric satellite insitu data from the sixties, seventies and early eighties were made accessible online in ASCII format for public use. This includes 14 data sets from the BE-B, Alouette 2, DME-A, AE-B, ISIS-1, ISIS-2, OGO-6, DE-2, AEROS-A, AE-C, AE-D, AE-E, and Hinotori satellites. The original data existed in various machine-specific, highly compressed, binary encoding on 7-, or 9-track magnetic tapes. The data were decoded and converted to a common ASCII data format, solar and magnetic indices were added, and some quality control measures were taken. The original intent of producing CD-ROMs with these data was overtaken by the rapid development of the Internet. Most users now prefer to obtain the data directly online and greatly value WWW-interfaces to browse, plot and subset the data. Accordingly the data were made available online on the anonymous ftp site of NASA's National Space Science Data Center (NSSDC) at ftp://nssdcftp.gsfc.nasa.gov/spacecraft data/ and on NSSDC's ATMOWeb (http://nssdc.gsfc.nasa.gov/atmoweb/), a WWW-interface for plotting, subsetting, and downloading the data. Several new features were implemented into ATMOWeb as part of this project including a filtering and scatter plot capability. The availability of this new database and WWW system was announced through several electronic mailer (AGU, CEDAR, IRI, etc) and through talks and posters during scientific meetings.

CD-ROM nutrient analysis database assists self-monitoring behavior of active duty Air Force personnel receiving nutrition counseling for weight loss.

Science.gov (United States)

Heetderks-Cox, M J; Alford, B B; Bednar, C M; Heiss, C J; Tauai, L A; Edgren, K K

2001-09-01

This study observed the effect of using a computerized vs manual method of self-monitoring among Air Force personnel receiving nutrition counseling for weight loss. Subjects who enrolled during the first 2 weeks of the 4-week recruitment period completed food records for 6 weeks using a CD-ROM nutrient database (intervention group) whereas those who enrolled during the last 2 weeks used a food record booklet (comparison group). Of the 42 subjects (n = 23 intervention group and n = 19 comparison group), only 113 intervention and 11 comparison group subjects (57% of study enrollees) submitted at least 1 food record during the study and were included in the analysis, which included review of pre- and poststudy questionnaires, food records, and focus group data. There were no significant differences between the number of days per week documented or average number of items recorded daily. All 9 intervention as compared to 2 comparison group subjects who completed a poststudy questionnaire searched for lower-energy and lower-fat items and reported changing their dietary intake as a result. All intervention group subjects who participated in a focus group (n=6) had favorable comments about using the CD-ROM for monitoring and changing eating habits, indicating that it is a beneficial self-monitoring tool. Participants enjoyed the immediate dietary feedback, and computerized food records may be easier to interpret by nutrition counselors. A number of computerized nutrient databases are available to assist patients and consumers in managing nutritional concerns.

Volcanoes of México: An Interactive CD-ROM From the Smithsonian's Global Volcanism Program

Science.gov (United States)

Siebert, L.; Kimberly, P.; Calvin, C.; Luhr, J. F.; Kysar, G.

2002-12-01

The Smithsonian Institution's Global Volcanism Program is nearing completion of an interactive CD-ROM, the Volcanoes of México. This CD is the second in a series sponsored by the U.S. Department of Energy Office of Geothermal Technologies to collate Smithsonian data on Quaternary volcanism as a resource for the geothermal community. It also has utility for those concerned with volcanic hazard and risk mitgation as well as an educational tool for those interested in Mexican volcanism. We acknowledge the significant contributions of many Mexican volcanologists to the eruption reports, data, and images contained in this CD, in particular those contributions of the Centro Nacional de Prevencion de Desastres (CENAPRED), the Colima Volcano Observatory of the University of Colima, and the Universidad Nacional Autónoma de México (UNAM). The Volcanoes of México CD has a format similar to that of an earlier Smithsonian CD, the Volcanoes of Indonesia, but also shows Pleistocene volcanic centers and additional data on geothermal sites. A clickable map of México shows both Holocene and Pleistocene volcanic centers and provides access to individual pages on 67 volcanoes ranging from Cerro Prieto in Baja California to Tacaná on the Guatemalan border. These include geographic and geologic data on individual volcanoes (as well as a brief paragraph summarizing the geologic history) along with tabular eruption chronologies, eruptive characteristics, and eruptive volumes, when known. Volcano data are accessible from both geographical and alphabetical searches. A major component of the CD is more than 400 digitized images illustrating the morphology of volcanic centers and eruption processes and deposits, providing a dramatic visual primer to the country's volcanoes. Images of specific eruptions can be directly linked to from the eruption chronology tables. The Volcanoes of México CD includes monthly reports and associated figures and tables cataloging volcanic activity in M�

English grammar in use a self-study reference and practice book for intermediate learners of English : with answers and CD-ROM

CERN Document Server

Murphy, Raymond

2012-01-01

English Grammar in Use Fourth edition is an updated version of the world's best-selling grammar title. It has a fresh, appealing new design and clear layout, with revised and updated examples, but retains all the key features of clarity and accessibility that have made the book popular with millions of learners and teachers around the world. The CD-ROM contains lots of additional practice exercises to consolidate learning, ideal for self-study but also suitable for reinforcement work in the classroom. An online version and book without answers are available separately.

Genetics, mental illness, and complex disease: development and distribution of an interactive CD-ROM for genetic counselors. Final report for period 15 August 2000 - 31 December 2002

Energy Technology Data Exchange (ETDEWEB)

McInerney, Joseph D.

2003-03-31

"Genetics and Major Psychiatric Disorders: A Program for Genetic Counselors" provides an introduction to psychiatric genetics, with a focus on the genetics of common complex disease, for genetics professionals. The program is available as a CD-ROM and an online educational resource. The on-line version requires a direct internet connection. Each educational module begins with an interactive case study that raises significant issues addressed in each module. In addition, case studies provided throughout the educational materials support teaching of major concepts. Incorporated throughout the content are expert video clips, video clips from individuals affected by psychiatric illness, and optional "learn more" materials that offer greater depth about a particular topic. The structure of the CD-ROM permits self-navigation, but we have suggested a sequence that allows materials to build upon each other. At any point in the materials, users may pause and look up terms in the glossary or review the DSM-IV criteria for selected psychiatric disorders. A detailed site map is available for those who choose to self navigate through the content.

Earth in Space: A CD-ROM Version for Pre-College Teachers

Science.gov (United States)

Pedigo, P.

2003-12-01

Earth in Space, a magazine about the Earth and space sciences for pre-college science teachers, was published by AGU between 1987 and 2001 (9 issues each year). The goal of Earth in Space was to make research at the frontiers of the geosciences accessible to teachers and students and engage them in thinking about scientific careers. Each issue contained two or three recent research articles, rewritten for a high school level audience from the original version published in peer-reviewed AGU journals, which were supplemented with short news items and biographic information about the authors. As part of a 2003 summer internship with AGU, sponsored by the AGU Committee on Education and Human Resources (CEHR) and the American Institute of Physics, this collection of Earth in Space magazines was converted into an easily accessible electronic resource for K-12 teachers and students. Every issue was scanned into a PDF file. The entire collection of articles was cataloged in a database indexed to key topic terms (e.g., volcanoes, global climate change, space weather). A front-page was designed in order to facilitate rapid access to articles concerning specific topics within the Earth and space sciences of particular interest to high school students. A compact CD-ROM version of this resource will be distributed to science teachers at future meetings of the National Science Teachers Association and will be made available through AGU's Outreach and Research Support program.

Analysis of potential energy saving strategies in a Bangkok school building. With CD-ROM; Analyse von Energieeinsparpotentialen am Beispiel einer Schule in Bangkok

Energy Technology Data Exchange (ETDEWEB)

Temming, H.V.

2000-05-01

In cooperation with the Gesellschaft fuer technische Zusammenarbeit GTZ, a school building in Thailand was selected for an analysis of potentials for energy saving. The selected school was the New International School of Thailand (NIST) in Bangkok. Energy-relevant data were acquired by measurements, and solutions for more efficient energy supply were developed. Recommendations were made on this basis. This dissertation is also available on CD-ROM. [German] In Zusammenarbeit mit der Gesellschaft fuer technische Zusammenarbeit GTZ wurde als Beispielobjekt eine thailaendische Schule, die New International School of Thailand (NIST) in Bangkok ausgewaehlt. An diesem Objekt wurden die verschiedenen energetischen Messungen durchgefuehrt. Diese wurden bedarfsgerecht ausgewertet. Auf der Basis der Ergebnisse wurden Loesungsmoeglichkeiten fuer eine effizientere Energieversorgung der Schule konstruiert und diese Alternativen wie oben beschrieben bewertet, woraus sich entsprechende Empfehlungen ergeben. Der Aufbau dieser Arbeit stellt sich nun folgendermassen dar: Nachdem in einem ersten Schritt die fuer diesen Kontext wichtigsten Parameter Thailands und des Untersuchungsobjektes dargestellt werden, schliesst sich hieran die Vorstellung verschiedener technische Alternativen zur Erzeugung von Kaelte an, da hier ein Fokus fuer moegliche Energieeinsparungen gesetzt wird. Anschliessend werden einige in der Arbeit verwandte Berechnungsverfahren fuer energetische oder wirtschaftliche Zuammenhaenge sowie eine ausfuehrliche Beschreibung der energetischen 1st-Situation des Untersuchungsobjektes dargestellt. Darauf aufbauend folgt nun die Vorstellung der verschiedenen Energieeinsparpotentiale durch technische und verhaltensinduzierte Optimierungsmassnahmen. Diese Arbeit endet mit der Bewertung aller aufgedeckten Potentiale und einem Gesamtfazit aus der Untersuchung. (Diese Diplomarbeit liegt auch in Form einer CD-ROM vor.) (orig./AKF)

Meteonorm. Global meteorological database for solar energy and applied climatology. Version 4.0: edition 2000. Software and data on CD-ROM

International Nuclear Information System (INIS)

1999-01-01

This is a comprehensive meteorological planning tool for system design, targeted at engineers, architects, teachers, planners and anyone interested in solar energy and climatology. METEONORM includes data from 2400 meteorological stations worldwide. Version V4.0 is based on over 15 years in the development of meteorological databases for energy. It may be used for solar applications at any desired location in the world, as an interpolation model of solar radiation and additional parameters for any site in the world is included. Also, with up-to-date algorithms, solar radiation incident on surfaces of arbitrary orientation may be calculated at the touch of a button. The local skyline profile may be specified. Five languages are supported: English, French, German, Italian, Spanish. Sites may be selected on map by means of a graphical interface. User data may be imported. 16 different output formats are available. Data, programme, manual, maps and illustrations are incorporated on the CD-ROM which is available for sale

Nuclear medicine installations supervisors interactive course (CD-ROM)

International Nuclear Information System (INIS)

Williart, A.; Shaw, M.; Tellez, M.

2000-01-01

The professionals who work as Nuclear Medicine Installations Supervisors need a suitable training. This training must be based on the guidelines of the C.S.N. (the Spanish Agency for Nuclear Safety). The traditional training courses must comply with a set of requirements, that not always is possible to get: They are given in a settled place. They are developed during a time, more or less lengthy. This time is pre-established. However, the persons willing to follow these courses have some difficulties with the place and the time. Many of them do not live near the places where the courses are given, in general in big cities, while there are Nuclear Medicine Installations scattered through all Spain. Moreover in some occasions they have not available time to attend the courses. Many times, faced with so many obstacles, the option is not to do the suitable training course. In order to solve this kind of problems we offer an Interactive Training Course (supported by CD-ROM). The course contents are based on Spanish Regulations and on the Safety Guide, established by C.S.N., for approval Radioactive Installations Supervisors Training Courses. This guide includes General Topics for Radioactive Installations and Specific Subjects for Nuclear Medicine. (General topics) Basic knowledge on the fundamental concepts on the action and nature of Ionizing Radiations, their risks and preventions. The ionizing radiations. Biological effects of ionizing radiations. Radiological protection. Legislation on radioactive installations. (Specific Subjects) Knowledge on the radiological risks associated to the proper techniques in the specific field of application. In our case the specific field is Nuclear Medicine Installations, where the radioactive sources are used for diagnostic or for therapy. Specific legal and administrative aspects. Non-encapsulated radioactive sources. Associated radiological risks to the use of non-encapsulated sources. Installations design. Operative procedures

The Cerefy registered clinical brain atlas on CD-ROM. Based on the classic Talairach-Tournoux and Schaltenbrand-Wahren brain atlases. 2. ed.

International Nuclear Information System (INIS)

Nowinski, W.L.; Thirunavuukarasuu, A.

2001-01-01

This remarkable CD-ROM provides enhanced and extended versions of three world-famous Thieme atlases, (Schaltenbrand and Wahren's Atlas for Stereotaxy of the Human Brain, Talairach and Tournoux's Co-Planar Stereotaxis Atlas of the Human Brain and Referentially Oriented Cerebral MRI Anatomy). It contains the electronic atlases as well as an easy navigation system to facilitate searching for and displaying more than 525 anatomical structures. Revolutionizing the field of brain anatomy, the authors have segmented, labeled, and cross referenced all the information contained in the books, and created contours for all three atlases. The Cerefy registered Clinical Brain Atlas now allows you to electronically navigate these atlases simultaneously on axial, coronal, and sagittal planes, and enjoy the ability to: 1. Access 210 high-quality, fully segmented, and labeled atlas images with corresponding contours, 2. Display and manipulate spatially co-registered atlases, 3. Dynamically label images with structure names and descriptions, and then highlight selected structures in the atlas image, 4. Image zoom in five different levels, mensurate, search, set triplanar, get coordinates, save, and print, 5. Access on-line help, glossary, and supportive atlas materials. (orig.)

The database system for the management of technical documentations of PWR fuel design project using CD-ROM

International Nuclear Information System (INIS)

Park, Bong Sik; Lee, Won Jae; Ryu, Jae Kwon; Jo, In Hang; Chang, Jong Hwa.

1996-12-01

In this report, the database system developed for the management of technical documentation of PWR fuel design project using CD-ROM (compact disk - read only memory) is described. The database system, KIRDOCM (KAERI Initial and Reload Fuel project technical documentation management), is developed and installed on PC using Visual Foxpro 3.0. Descriptions are focused on the user interface of the KIRDOCM. Introduction addresses the background and concept of the development. The main chapter describes the user requirements, the analysis of computing environment, the design of KIRDOCM, the implementation of the KIRDOCM, user's manual of KIRDOCM and the maintenance of the KIRDOCM for future improvement. The implementation of KIRDOCM system provides the efficiency in the management, maintenance and indexing of the technical documents. And, it is expected that KIRDOCM may be a good reference in applying Visual Foxpro for the development of information management system. (author). 2 tabs., 13 figs., 8 refs

The Virtual 3D Reconstruction of the East Pediment of the Temple of Zeus at Olympia – Presentation of an Interactive CD-ROM

Directory of Open Access Journals (Sweden)

András PATAY-HORVÁTH Patay-Horváth

2011-12-01

Full Text Available The paper gives an overview of a two-years project concerning a major monument of ancient Greek art and presents the interactive, bilingual (English/Hungarian CD-ROM, which is intended to summarize and visualize its final results. The presented project approaches a century-old controversy in a new way by producing a virtual 3D reconstruction of a monumental marble group. Digital models of the statues were produced by scanning the original fragments and by reconstructing them virtually. The virtual model of the pediment surrounding the sculptures was prepared on the basis of the latest architectural studies and afterwards the reconstructed models were inserted in this frame, in order to test the technical feasibility and aesthetic effects the four possible arrangements. The resulting models enable easy and very instructive experimentation, which would be otherwise impossible with the originals and/or very expensive and not very practicable with traditional tools (e.g. real-size plaster models. The complete model can effectively be used to verify the results of earlier or more recent reconstructions presented only in simple drawings. In addition, the 3D models of the individual fragments can be used for further research and for visualization.  The documentary CD-ROM presenting the full background, the methods and the conclusions of the project contains beside a comprehensive text various kinds of supporting documents (images, 3D models, papers, broadcasts, audiovisual material. It is addressed to a mixed audience: a picture gallery, a short documentary movie some other attachments including a selected bibliography is intended for the general public, but scholarly publications, presentations on related problems are also included for specialists interested in certain details.

Arkitekturen, Roms moderne bygningsværker

DEFF Research Database (Denmark)

Hansen, Peter Mandal

2012-01-01

Artikel om Roms moderne og nutidige arkitektur med beskrivelse og analyse af et udvalg af Roms markante bygningsværker.......Artikel om Roms moderne og nutidige arkitektur med beskrivelse og analyse af et udvalg af Roms markante bygningsværker....

The development and pilot testing of a multimedia CD-ROM for diabetes education.

Science.gov (United States)

Castaldini, M; Saltmarch, M; Luck, S; Sucher, K

1998-01-01

The multimedia CD-ROM program, Take Charge of Diabetes, was found to be accurate, easy to use, and enjoyable by the clients and health professionals who completed the pilot study. Participants perceived an increase in knowledge after completing the five modules. Two of the participants verbally stated that the program clarified information for them and they wished they had had such a program when they were first diagnosed with diabetes. Further evaluation is needed to generalize the effect of the program on knowledge of diabetes because the pilot study was not designed to fully evaluate the effectiveness of the program on knowledge level or behavior change. Behavior change resulting in better control of blood sugar levels and hemoglobin A1c within normal range is the goal for diabetes education. The person who lives with diabetes must learn self-care methods. To accomplish that, the person must be able to comprehend the material presented. CAI programs provide an individualized, interactive, and interesting way to learn about diabetes and self-care, using visual effects and audio to support the written text. CAI can provide an element of excitement that is not available with other conventional methods. Providing prompt reinforcement of correct answers in quiz sections and including positive written messages can increase patients' self-confidence and self-esteem. Computer-assisted instruction is not intended to replace personal contact with physicians and diabetes educators, but rather complement this contact, reinforce learning, and possibly increase self-motivation to take charge of one's diabetes.

Cern DD4424 ROM Diode Matrix

CERN Multimedia

A diode matrix is an extremely low-density form of read-only memory. It's one of the earliest forms of ROMs (dating back to the 1950s). Each bit in the ROM is represented by the presence or absence of one diode. The ROM is easily user-writable using a soldering iron and pair of wire cutters.This diode matrix board is a floppy disk boot ROM for a PDP-11, and consists of 32 16-bit words. When you access an address on the ROM, the circuit returns the represented data from that address.

A, B, CD, DVD: Marketing Higher Education to the Millennial Generation

Science.gov (United States)

Furbeck, Lee F.; Harding, Marc L.; Wohlgemuth, Darin R.; Bousquet, David R.

2003-01-01

Based on compelling financial and strategic reasons, Iowa State University replaced its paper viewbook with a CD-ROM digital viewbook following the Fall 1998 recruiting cycle. The first interactive DVD viewbook debuted for the Fall 2003 recruiting cycle, following a qualitative research study designed to gauge the effectiveness of the medium.…

GeomarCD project; an educational CD-Rom about marine geophysics

Science.gov (United States)

Diaz, J.; Rubio, E.; Gómez, M.; Gallart, J.

2009-04-01

This project aims to introduce the main aspects of marine geophysics experiments to the high school students. We have chosen to present the information in the form an interactive game in which, taking care of the scientific objectives and the technological and logistic resources, the player must found the best strategy to make one of the 3 research projects proposed. Along the game, the player is introduced to the main aspects of the plate tectonics theory and the crustal structure as well as to the main methodologies available (seismics, potencial fields, cores). Rather than being based in theoretical aspects, largely covered by other outreach projects, this work focuses in how a realistic problem can be solved through a field experiment. The game takes place in the researcher's desk and in an oceanographic vessel as the BIO Hesperides and includes the choice of the research project, the design and development of the field work and the interpretation of the results. At the end, the player must complete a questionnaire to elaborate the final report. The correct choice of the appropriate methodologies and its interpretation is necessary to succeed. CD copies in Spanish are freely available upon request.

SOFTWARE REVIEW: Multimedia Motion II. CD-ROM and Teacher's Guide

Science.gov (United States)

Scaife, Jon A.

2000-05-01

expect. This is an issue that is in the teacher's hands; the package is flexible enough to accommodate a wide range of learning aims. Audio clips are brief and to the point, with both female and male speakers. The commentary goes beyond the descriptive, raising interesting questions and issues and setting challenges for the user. The optional screen text is pitched at A-level. Video clips can be viewed at full screen, which is a big improvement over the first edition. There are some new clips and a few omissions from the first edition; further CDs of movie data are planned. Clips may be played forwards or backwards at various speeds using a scroll bar. This allows close control and analysis, which is useful for critical events in which changes are rapid, such as collisions. Printing of data and graphs is straightforward and the results are clear. Unlike the first edition, Multimedia Motion II only gives direct support to graphs with time as the abscissa. For graphs such as v(x) versus v(y), however, it is a simple matter to save the data directly into Excel or another spreadsheet. I encountered only one snag in using the CD: if I forgot to save my data before moving to a new clip I could not recover it. This failing could be mine, but I did try hard. The Teacher's Guide contains photocopiable worksheets and detailed discussion and graphs of the video clips. For each clip there is a section of `useful data and formulae'. The guide is not a necessity for using the CD-ROM but it would be a very handy A-level teaching resource, allowing the option of independent use by students. It is accompanied by a floppy disc containing sets of experimental data for the video clips, a useful option for quick demonstrations. In addition, the guide explains the interesting and creative option of making your own movie sequences from videotape, though access to a video card would be needed to do this. Imagine the motivational value of students recording themselves playing various sports, or

School Library Supplement. Putting Your Library Automation System to Work [and] Using Videodiscs in Research Projects [and] Library Security: What to Look For [and] Expanding Library/Media Services with Media Retrieval [and] How to Network CD-ROMs (and) The School Library Resource Directory.

Science.gov (United States)

Karpisek, Marian; And Others

1995-01-01

Presents five articles and a company resource directory to help librarians successfully incorporate technology into school libraries. Discusses actual situations, examines student needs, and gives advice to help librarians with library automation systems, videodiscs, library security systems, media retrieval, networking CD-ROMs, and locating…

Nonlinear Aerodynamic ROM-Structural ROM Methodology for Inflatable Aeroelasticity in Hypersonic Atmospheric Entry, Phase I

Data.gov (United States)

National Aeronautics and Space Administration — ZONA Technology proposes to develop an innovative nonlinear structural reduced order model (ROM) - nonlinear aerodynamic ROM methodology for the inflatable...

Kodak's New Photo CD Portfolio: Multimedia for the Rest of Us.

Science.gov (United States)

Bonime, Andrew

1994-01-01

Describes Photo CD Portfolio, an Eastman Kodak product that provides interactive multimedia CD-ROM production capability. The article focuses on the capabilities of the tool's simplest authoring system, Create It, which allows users to work with Photo CD, PICT, or TIFF images, add graphics, text and audio, and create menus with branching. (KRN)

Numerical Recipes in C++: The Art of Scientific Computing (2nd edn). Numerical Recipes Example Book (C++) (2nd edn). Numerical Recipes Multi-Language Code CD ROM with LINUX or UNIX Single-Screen License Revised Version

International Nuclear Information System (INIS)

Borcherds, P

2003-01-01

(C++), the authors point out some of the problems in the use of C++ in scientific computing. I have not found any mention of parallel computing in NR(C++). Fortran has quite a lot going for it. As someone who has used it in most of its versions from Fortran II, I have seen it develop and leave behind other languages promoted by various enthusiasts: who now uses Algol or Pascal? I think it unlikely that C++ will disappear: it was devised as a systems language, and can also be used for other purposes such as scientific computing. It is possible that Fortran will disappear, but Fortran has the strengths that it can develop, that there are extensive Fortran subroutine libraries, and that it has been developed for parallel computing. To argue with programmers as to which is the best language to use is sterile. If you wish to use C++, then buy NR(C++), but you should also look at volume 2 of NR(F). If you are a Fortran programmer, then make sure you have NR(F), volumes 1 and 2. But whichever language you use, make sure you have one version or the other, and the CD ROM. The Example Book provides listings of complete programs to run nearly all the routines in NR, frequently based on cases where an analytical solution is available. It is helpful when developing a new program incorporating an unfamiliar routine to see that routine actually working, and this is what the programs in the Example Book achieve. I started teaching computational physics before Numerical Recipes was published. If I were starting again, I would make heavy use of both The Art of Scientific Computing and of the Example Book. Every computational physics teaching laboratory should have both volumes: the programs in the Example Book are included on the CD ROM, but the extra commentary in the book itself is of considerable value. (book review: Press, William H; Teukolsky, Saul A; Vettering, William T; Flannery, Brian P - ISBN 0-521-75034-4; ISBN 0-521-75034-2; ISBN 0-521-75036-9)

ROM a primera vista = ROM at first sight

Directory of Open Access Journals (Sweden)

Hugo Ricardo, D

2006-09-01

Full Text Available RESUMEN Objetivo:Es por todos conocida la importancia en la medición delROM (Range of motion: Rango de movimiento de una articulación, como elemento diagnóstico y evolutivo, pero, falta de uniformidad existe respecto a como debería ser registrado el ROM, de manera tal que otros profesionales pudieran interpretar los mismos resultados. Es objetivo de este trabajo, presentar una nueva técnica, rápida y eficaz para medir el ROM activo de las articulaciones de muñeca y dedos, sin necesidad de recurrir a un goniómetro o sistema similar.Material y métodos: La técnica se basa en darle a cada rango articular, desde la posición extrema, un valor máximo de 1 y un mínimo de 0 . Por ejemplo, si la extensión de muñeca es total, entonces corresponde valor 1; si la extensión de muñeca, no existe, entonces corresponde un valor de 0. Si la extensión llega a un 25% , se considera valor¼. Si la extensión llega a un 50%, se considera valor ½ .Si la extensión llega a un 75%, se considera valor ¾. Además, si al valor del ROM obtenido, le adosamos luego de un guión el valor 0, indicaráausencia de dolor. Si adosamos el valor 1, indicará presencia de dolor.Discusión: Esta técnica tiene evidentemente ciertas ventajas respecto a los métodos convencionales: Es más rápida, más cómoda, más simple, más fácil de aprender y recordar, y otros profesionales pueden apropiadamente interpretar los mismos resultados ABSTRACTObjective: we all are aware of the importance of the measuring of ROM in an articulation, as an element for diagnosis and evolution. Notwithstanding, there is a lack of uniformity concerning its registration to facilitate theinterpretation of the same results by other professionals.So that, the aim of this work is presenting a new, quick and effective technique to measure the active ROM of wrist and fingers joints without resorting to a goniometer or similar device.Material and methods: this technique consists of giving each

Development of a CD-ROM on written language for the continuing education of elementary school teachers

Directory of Open Access Journals (Sweden)

Thaís dos Santos Gonçalves

2011-12-01

Full Text Available Distance education has emerged to minimize the anxiety of many professionals who need to update their knowledge, but do not have the time and opportunity to travel to educational centers. Objectives: To describe the development of a CD-ROM to provide distance continuing education to basic school teachers that addresses issues related to written language. Material and Methods: Previously, a script was developed with themes related to the acquisition and development of written language. Subsequently, a technical team transformed the texts in multimedia language. Results: The titles of each content area addressed are available on buttons and links. The files can be viewed in a linear sequence, allowing the teacher to start learning at the desired moment and go straight to the file that he or she wants to access. Videos that show practical applications of the concepts available in text are included. Conclusions: Brazil is a developing country. The use of technologies for education reduces cultural isolation among education professionals. It is necessary to focus on making teaching materials for distance education. In order to provide an effective learning environment, the learners reality should be considered. A multidisciplinary team should prepare the materials. The development of educational material for distance education on the acquisition and development of written language seems not only appropriate, but also warranted to provide professional growth opportunity for teachers who need time flexibility and/or live far away from academic centers.

Wind Resource Atlas of Oaxaca (CD-ROM)

Energy Technology Data Exchange (ETDEWEB)

Elliott, D.; Schwartz, M.; Scott, G.; Haymes, S.; Heimiller, D.; George, R.

2003-08-01

The CD version of the Oaxaca Wind Resource Atlas, produced by the National Renewable Energy Laboratory's (NREL's) wind resource group, is the result of an extensive mapping study for the Mexican State of Oaxaca. This atlas identifies the wind characteristics and distribution of the wind resource in Oaxaca. The detailed wind resource maps and other information contained in the atlas facilitate the identification of prospective areas for use of wind energy technologies, both for utility-scale power generation and off-grid wind energy applications.

A multimedia case based approach to the study of office ergonomics.

Science.gov (United States)

August-Dalfen, Sharon; Snider, Laurie

2003-01-01

Multimedia technology has the capacity to provide students with an interactive approach to problem based learning and to bridge the gap between theoretical knowledge and clinical practice. The present paper describes the design and development of the program ErgoROM, a CD which presents a case study to assist occupational therapy students in their studies of office ergonomics. A pilot study showed that overall, 91% of respondents rated the ErgoROM as either "Excellent" or "Very Good". Additionally they reported that ErgoROM had a positive impact on active learning and critical thinking.

Status and trends of nuclear technologies - Report of the International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO). Additional information (Companion CD-ROM)

International Nuclear Information System (INIS)

2009-09-01

The International Project on Innovative Nuclear Reactors and Fuel Cycles (INPRO) was launched in the year 2000, based on a resolution by the IAEA General Conference (GC(44)/RES/21). INPRO intends to help to ensure that nuclear energy is available in the 21st century in a sustainable manner, and seeks to bring together all interested Member States, both technology holders and technology users, to consider, jointly, actions to achieve desired innovations. INPRO is taking care of the specific needs of developing countries. This IAEA publication is part of Phase 1 of INPRO. It intends to provide an overview on history, present situation and future perspectives of nuclear fuel cycle technologies. While this overview focuses on technical issues, nevertheless, the aspects of economics, environment, and safety and proliferation resistance are important background issues for this study. After a brief description about the INPRO project and an evaluation of existing and future reactor designs the publication covers nuclear fuel cycle issues in detail. It is expected that this documentation will provide IAEA Member States and their nuclear engineers and designers, as well as policy makers with useful information on status and trends of future nuclear fuel cycle technologies. Due to the size of the full report it was decided to attach a CD-ROM in the back of the summary report

Acceptability and preliminary feasibility of an internet/CD-ROM-based education and decision program for early-stage prostate cancer patients: randomized pilot study.

Science.gov (United States)

Diefenbach, Michael A; Mohamed, Nihal E; Butz, Brian P; Bar-Chama, Natan; Stock, Richard; Cesaretti, Jamie; Hassan, Waleed; Samadi, David; Hall, Simon J

2012-01-13

Prostate cancer is the most common cancer affecting men in the United States. Management options for localized disease exist, yet an evidence-based criterion standard for treatment still has to emerge. Although 5-year survival rates approach 98%, all treatment options carry the possibility for significant side effects, such as erectile dysfunction and urinary incontinence. It is therefore recommended that patients be actively involved in the treatment decision process. We have developed an Internet/CD-ROM-based multimedia Prostate Interactive Educational System (PIES) to enhance patients' treatment decision making. PIES virtually mirrors a health center to provide patients with information about prostate cancer and its treatment through an intuitive interface, using videos, animations, graphics, and texts. (1) To examine the acceptability and feasibility of the PIES intervention and to report preliminary outcomes of the program in a pilot trial among patients with a new prostate cancer diagnosis, and (2) to explore the potential impact of tailoring PIES treatment information to participants' information-seeking styles on study outcomes. Participants (n = 72) were patients with newly diagnosed localized prostate cancer who had not made a treatment decision. Patients were randomly assigned to 3 experimental conditions: (1) control condition (providing information through standard National Cancer Institute brochures; 26%), and PIES (2) with tailoring (43%) and (3) without tailoring to a patient's information-seeking style (31%). Questionnaires were administrated before (t1) and immediately after the intervention (t2). Measurements include evaluation and acceptability of the PIES intervention, monitoring/blunting information-seeking style, psychological distress, and decision-related variables (eg, decisional confidence, feeling informed about prostate cancer and treatment, and treatment preference). The PIES program was well accepted by patients and did not interfere

A CD-ROM About Radiation Protection Aspects of a Nuclear Accident: Towards more Openness and Transparency

International Nuclear Information System (INIS)

Oudiz, Andre

2003-01-01

Many players are involved in managing a nuclear accident apart from radiation protection and nuclear safety experts. In an emergency response situation, the decision making process involves many non-technical players who nonetheless have a major role to play: in France these may include the 'Prefet', the emergency and civil defence services, the health services, the police, the 'gendarmerie' and local councillors, with advice from the safety and radiological protection authorities and expert evaluation organisations. Within the post-accident response, other players will be involved alongside those already described : professional bodies, particularly farming organisations, residents' associations, those responsible for environmental decontamination, agencies responsible for compensating victims, etc., etc. In both the short and the long-term phases of the crisis management process, it is essential to enable participants who may have very different -backgrounds and professional experience to work together with co-operation and mutual understanding. If non-technical players are to contribute effectively, there needs to be a minimum level of mutual understanding between them and the technical. players on what the nuclear risk really is and what is the rationale of the short and long term counter-measures aimed at protecting the public and restoring the contaminated environment. Local communities also need to share this basic understanding because their cooperation is required in order to implement the countermeasures properly. Conversely, if the experts are to advise the local authorities properly, they need to understand the criteria on which these local authorities and communities base their decisions: what psycho sociological factors apply, what logistical support is needed, what are the concerns of the local communities? The CD-ROM should help in gradually building up a shared interpretation or culture of the nuclear risk. This forum should promote debate that is

Mawul Rom Project: Openness, obligation and reconciliation

NARCIS (Netherlands)

Brigg, M.; Tonnaer, A.A.C.

2008-01-01

Aboriginal Australian initiatives to restore balanced relationships with White Australians have recently become part of reconciliation efforts. This paper provides a contextualised report on one such initiative, the Mawul Rom cross-cultural mediation project. Viewing Mawul Rom as a diplomatic

Review of Excavating Occaneechi Town: Archaeology of an Eighteenth-Century Indian Village in North Carolina. 1998, edited by R.P. Stephen Davis Jr., Patrick C. Livingood, Trawick Ward, and Vincas P. Steponaitis. University of North Carolina Press. ISBN 0-8078-6503-6 [CD-ROM

Directory of Open Access Journals (Sweden)

Jonathan Bateman

1999-05-01

Full Text Available The CD-ROM Excavating Occaneechi Town: Archaeology of an Eighteenth-Century Indian Village in North Carolina has become a familiar site on my desk in the last few months. Not, I admit, because I have been avidly scouring its content on a regular basis, but because I have been putting off writing this review. A wealth of information can be an intimidating thing.

Development of an Integrated Approach to Routine Automation of Neutron Activation Analysis. Results of a Coordinated Research Project. Companion CD-ROM. Annex II: Country Reports

International Nuclear Information System (INIS)

2018-04-01

Neutron activation analysis (NAA) is a powerful technique for determining bulk composition of major and trace elements. Automation may contribute significantly to keep NAA competitive for end-users. It provides opportunities for a larger analytical capacity and a shorter overall turnaround time if large series of samples have to be analysed. This publication documents and disseminates the expertise generated on automation in NAA during a coordinated research project (CRP). The CRP participants presented different cost-effective designs of sample changers for gamma-ray spectrometry as well as irradiation devices, and were able to construct and successfully test these systems. They also implemented, expanded and improved quality control and quality assurance as cross-cutting topical area of their automated NAA procedures. The publication serves as a reference of interest to NAA practitioners, experts, and research reactor personnel, but also to various stakeholders and users interested in basic research and/or services provided by NAA. This CD-ROM contains the individual country reports

Comment scolariser les enfants Roms? Les enfants Roms dans les dispositifs mis en place à Bordeaux Métropole.

OpenAIRE

Øhlund, Ida

2016-01-01

Dans ce mémoire, je m intéresse à la scolarisation des enfants Roms en France. Je présente la place des enfants Roms dans la scolarisation en Europe et en France. Je discute les efforts qu on fait en France pour scolariser ces enfants, et je prends comme exemple les mesures d intégration prises par les autorités de Bordeaux Métropole en expliquant les rôles des différents acteurs locaux. Dans la première partie, j essaye de présenter le groupe minoritaire européen appelé « Rom ». J aborde l h...

Ambient Temperature Based Thermal Aware Energy Efficient ROM Design on FPGA

DEFF Research Database (Denmark)

Saini, Rishita; Bansal, Neha; Bansal, Meenakshi

2015-01-01

Thermal aware design is currently gaining importance in VLSI research domain. In this work, we are going to design thermal aware energy efficient ROM on Virtex-5 FPGA. Ambient Temperature, airflow, and heat sink profile play a significant role in thermal aware hardware design life cycle. Ambient...

Noziegums un sods Grama Svifta romānā "Dienas gaisma" un Fjodora Dostojevska romānā "Noziegums un sods"

OpenAIRE

Hohlova, Marija

2008-01-01

Šis bakalaura darbs pēta nozieguma un soda tēmu Fjodora Dostojevska romānā "Noziegums un sods" un Grema Svifta romānā "Dienas gaisma". Darbs sastāv no četrām nodaļām. Pirmajā nodaļā, kura pamatīgi aplūko nozieguma folozofiju, autore piemin integrēto pieeju nozieguma parādībai folozofijas skatījumā, kā arī analīzē nozieguma metafiziskās un socioloģiskās īpatnības uz Fjodora Dostojevska romāna "Noziegums un sods" pamata. Otrā nodaļa apraksta Fjodora Dostojevska romāna "Noziegums un sods" un Gre...

Advances in Neutron Activation Analysis of Large Objects with Emphasis on Archaeological Examples. Results of a Coordinated Research Project. Annex II. Companion CD-ROM

International Nuclear Information System (INIS)

2018-03-01

This publication is a compilation of the main results and findings of an IAEA coordinated research project (CRP). In particular, it discusses an innovative variation of neutron activation analysis (NAA) known as large sample NAA (LSNAA). There is no other way to measure the bulk mass fractions of the elements present in a large sample (up to kilograms in mass) non-destructively. Examples amenable to LSNAA include irregularly shaped archaeological artefacts, excavated rock samples, large samples of assorted ore, and finished products, such as nuclear reactor components. Advantages of LSNAA applications, limitations and scientific and technological requirements are described in this publication, which serves as a reference of interest not only to the NAA experts, research reactor personnel, and those considering this technique, but also to various stakeholders and users such as researchers, industrialists, environmental and legal experts, and administrators. The county reports given in this companion CD-ROM (Annex II) give a global overview of all the accomplishments achieved by the participants during the CRP. However, in several cases common procedures were employed by several participating laboratories, constituting one general approach.

ChemSkill Builder 2000, Version 6.1 [CD-ROM] (by James D. Spain and Harold J. Peters)

Science.gov (United States)

Keeney-Kennicutt, Reviewed By Wendy L.

2000-07-01

One of the major challenges for faculty teaching general chemistry is how to encourage students to practice solving problems. We know that for students to develop chemical intuition and problem-solving skills, they must "get their hands dirty" as they decipher and unravel problems inherent to our discipline. One tool that I've used since its release in 1996 is the ChemSkill Builder, an electronic homework package. The latest version, ChemSkill Builder (CSB) 2000, version 6.1, is an excellent, effective integration of teaching and testing most quantitative and conceptual learning objectives in an interactive way. It is inexpensive and easy to use for both students and faculty. The CSB 2000 package of personalized problem sets, specifically designed to complement most general chemistry courses, is a program on CD-ROM for PC Windows users (3.1, 95, or 98), with more than 1500 questions and a 3 1/2-in. record-management disk. There is a separate grade-management disk for the instructor. It has 24 gradable chapters, each with 5 or 6 sections, plus two new chapters that are not graded: Polymer Chemistry and an Appendix of Chemical Skills. Each section begins with a short review of the topic and many have interactive explanations. If students miss an answer, they are given a second chance for 70% credit. If they still miss, the worked-out solution is presented in detail. Students can work each section as many times as they wish to improve their scores. Periodically, the students download their data directly into a PC set up by the instructor. The data can be easily converted into an ASCII file and merged with a spreadsheet. The use of CD-ROM solves the sporadic problems associated with previous versions on 3 1/2-in. disks: software glitches, failed disks, and system incompatibilities. The quality and number of graphics and interactive exercises are much improved in this latest version. I particularly enjoyed the interactive explanations of significant figures and

IDC Reengineering Phase 2 & 3 Rough Order of Magnitude (ROM) Cost Estimate Summary (Leveraged NDC Case).

Energy Technology Data Exchange (ETDEWEB)

Harris, James M.; Prescott, Ryan; Dawson, Jericah M.; Huelskamp, Robert M.

2014-11-01

Sandia National Laboratories has prepared a ROM cost estimate for budgetary planning for the IDC Reengineering Phase 2 & 3 effort, based on leveraging a fully funded, Sandia executed NDC Modernization project. This report provides the ROM cost estimate and describes the methodology, assumptions, and cost model details used to create the ROM cost estimate. ROM Cost Estimate Disclaimer Contained herein is a Rough Order of Magnitude (ROM) cost estimate that has been provided to enable initial planning for this proposed project. This ROM cost estimate is submitted to facilitate informal discussions in relation to this project and is NOT intended to commit Sandia National Laboratories (Sandia) or its resources. Furthermore, as a Federally Funded Research and Development Center (FFRDC), Sandia must be compliant with the Anti-Deficiency Act and operate on a full-cost recovery basis. Therefore, while Sandia, in conjunction with the Sponsor, will use best judgment to execute work and to address the highest risks and most important issues in order to effectively manage within cost constraints, this ROM estimate and any subsequent approved cost estimates are on a 'full-cost recovery' basis. Thus, work can neither commence nor continue unless adequate funding has been accepted and certified by DOE.

Reactive oxygen metabolites (ROMs) are associated with cardiovascular disease in chronic hemodialysis patients.

Science.gov (United States)

Bossola, Maurizio; Vulpio, Carlo; Colacicco, Luigi; Scribano, Donata; Zuppi, Cecilia; Tazza, Luigi

2012-02-11

The aim of our study was to measure reactive oxygen metabolites (ROMs) in chronic hemodialysis (HD) patients and evaluate the possible association with cardiovascular disease (CVD) and mortality. We measured ROMs in 76 HD patients and correlated with CVD, cardiovascular (CV) events in the follow-up and all-cause and CVD-related mortality. The levels of ROMs presented a median value of 270 (238.2-303.2) CARR U (interquartile range). We created a ROC curve (ROMs levels vs. CVD) and we identified a cut-off point of 273 CARR U. Patients with ROMs levels ≥273 CARR U were significantly older, had higher C-reactive protein levels and lower creatinine concentrations. The prevalence of CVD was higher in patients with ROMs levels ≥273 (87.1%) than in those with ROMs levels <273 CARR U (17.7%; p<0.0001). ROMs levels were significantly higher in patients with CVD (317±63.8) than in those without (242.7±49.1; p<0.0001). At multiple regression analysis, age, creatinine and C-reactive protein were independent factors associated with ROMs. At multiple logistic regression analysis the association between ROMs and CVD was independent (OR: 1.02, 95% CI: 1.00-1.05; p=0.03). Twenty six patients developed cardiovascular (CV) events during the follow-up. Of these, seven were in the group with ROMs levels <273 CARR U and 19 in the group with ROMs levels ≥273 CARR U. The logistic regression analysis showed that both age (OR: 1.06, 95% CI: 1.01-1.12; p=0.013) and ROMs levels (OR: 1.10, 95% CI: 1.00-1.02; p=0.045) were independently associated with CV events in the follow-up. ROMs are independently associated with CVD and predict CV events in chronic HD patients.

Syd for Rom

DEFF Research Database (Denmark)

Frandsen, Steen Bo

Bogen fortæller historien om et af Europas mest berømte vildnisser, De Pontinske Sumpe, der strakte sig i kystlandet umiddelbart syd for Rom fra romertiden til tørlægningen og forvandlingen til landbrugsland i 1930'erne. Allerede under romerne vandt sumpen uophørligt terræn og forvandlede det fla...

ROMS/TOMS Tangent Linear and Adjoint Models: Testing and Applications

National Research Council Canada - National Science Library

Miller, Arthur J; Cornuelle, Bruce D

2004-01-01

... (Regional Ocean Modeling System/Terrain-Following Ocean Modeling System) that is suitable for general use by the ROMS/TOMS community and to develop computational platforms based on the TLM and ADM for 4D variational data assimilation (4DVar...

Deutsche Literatur von Frauen – Jetzt auch digital! Literature by German Women—Now on CD!

Directory of Open Access Journals (Sweden)

Corinna Heipcke

2002-07-01

Full Text Available Die Digitale Bibliothek hat eine CD-Rom ediert, auf der ein Querschnitt durch die Werke von Autorinnen aus vier Jahrhunderten enthalten ist. Die Volltexte sind integriert in ein Bearbeitungsprogramm, das quellentreues Zitieren und Volltextrecherchen ermöglicht. Damit ist ein ausgesprochen praktisches Hilfsmittel für Germanistinnen und Germanisten entstanden. An ihre Grenzen gelangt die Sammlung allerdings bei der nicht unproblematischen Textauswahl.The editors of the Digital Library have tackled the task of creating a library which enables one to find any work that one may be interested in looking up or reading. Five years ago, a CD Rom entitled German Literature from Lessing to Kafka which present the complete works of select authors together with a programme that assists the user in better understanding their works. In so doing, however, women were almost completely omitted, as the entire CD only featured the works of four women authors. In order to overcome this shortcoming, Mark Lehmstedt edited the above-mentioned CD which contains the select works of 62 women authors from the baroque period to the Weimar Republic. Their works are accompanied by the latest software version of the Digital Library.

Our God is Gold: Vlashika Rom at a Crossroads?

Directory of Open Access Journals (Sweden)

Andrš Zbyněk

2016-12-01

Full Text Available This article explicates the sociocultural dynamics in the changing lives of the Vlashika Rom group in the Czech and Slovak Republics and contemplates the prospective development of this Roma subculture. To provide a better insight into the endeavour of the Vlashika Rom to maintain their integrity and into their adaptation strategies, the author outlines the genesis of this subethnic group, pointing out the historical circumstances that have formed them in the past. Contrary to former descriptions, the author provides an entirely new concept for dividing the Vlashika Rom into subgroups, identifying three distinct levels that create social boundaries within this community. He describes the way of living of this subgroup in the past as well as the relationships between the Vlashika Rom and the dominant society. Frequently antagonistic, these relationships depend on their way of life, substantially determined by the way they earn their living. The author analyses the inner resources that keep sustaining the contemporary Vlashika Rom culture and, drawing on his own experience and impulses from literature, inquires how long this anachronistic yet at the same time very adaptable culture will be able to resist the assimilation pressures deriving from the very nature of the modern national state.

Near-Horizontal, Two-Phase Flow Patterns of Nitrogen and Hydrogen at Low Mass Heat and Flux (on CD-ROM)

Science.gov (United States)

VanDresar, N. T.; Siegwarth, J. D.

2001-01-01

One reason for NASA's interest in cryogenic two-phase flow with low mass and heat flux is the need to design spacecraft heat exchangers used for vaporizing cryogenic propellants. The CD-ROM provides digitized movies of particular flow patterns observed in experimental work. The movies have been provided in (QuickTime9Trademark) format, encoded at 320w x 240h pixels, 15 fps, using the Sorenson(Trademark) Video Codec for compression. Experiments were conducted to obtain data on the two-phase (liquid and vapor) flow behavior of cryogenic nitrogen and hydrogen under low mass and heat flux conditions. Tests were performed in normal gravity with a 1.5 degree up flow configuration. View ports in the apparatus permitted visual observation of the two-phase flow patterns. Computer codes to predict flow patterns were developed from theoretical/empirical models reported in the literature. Predictions from the computer codes were compared with experimental flow pattern observations. Results are presented employing the traditional two-dimensional flow pattern map format using the liquid and gas superficial velocities as coordinates. In general, the agreement between the experimental results and the analytical predictive methods is reasonably good. Small regions of the flow pattern maps are identified where the models are deficient as a result of neglecting phase change phenomena. Certain regions of the maps were beyond the range of the experiments and could not be completely validated. Areas that could benefit from further work include modeling of the transition from separated flow, collection of additional data in the bubble and annular flow regimes, and collection of experimental data at other inclination angles, tube diameters and high heat flux.

[Benchmarking and other functions of ROM: back to basics].

Science.gov (United States)

Barendregt, M

2015-01-01

Since 2011 outcome data in the Dutch mental health care have been collected on a national scale. This has led to confusion about the position of benchmarking in the system known as routine outcome monitoring (rom). To provide insight into the various objectives and uses of aggregated outcome data. A qualitative review was performed and the findings were analysed. Benchmarking is a strategy for finding best practices and for improving efficacy and it belongs to the domain of quality management. Benchmarking involves comparing outcome data by means of instrumentation and is relatively tolerant with regard to the validity of the data. Although benchmarking is a function of rom, it must be differentiated form other functions from rom. Clinical management, public accountability, research, payment for performance and information for patients are all functions of rom which require different ways of data feedback and which make different demands on the validity of the underlying data. Benchmarking is often wrongly regarded as being simply a synonym for 'comparing institutions'. It is, however, a method which includes many more factors; it can be used to improve quality and has a more flexible approach to the validity of outcome data and is less concerned than other rom functions about funding and the amount of information given to patients. Benchmarking can make good use of currently available outcome data.

Thoracic ROM measurement system with visual bio-feedback: system design and biofeedback evaluation.

Science.gov (United States)

Ando, Takeshi; Kawamura, Kazuya; Fujitani, Junko; Koike, Tomokazu; Fujimoto, Masashi; Fujie, Masakatsu G

2011-01-01

Patients with diseases such as chronic obstructive pulmonary disease (COPD) need to improve their thorax mobility. Thoracic ROM is one of the simplest and most useful indexes to evaluate the respiratory function. In this paper, we have proposed the prototype of a simple thoracic ROM measurement system with real-time visual bio-feedback in the chest expansion test. In this system, the thoracic ROM is measured using a wire-type linear encoder whose wire is wrapped around the thorax. In this paper, firstly, the repeatability and reliability of measured thoracic ROM was confirmed as a first report of the developed prototype. Secondly, we analyzed the effect of the bio-feedback system on the respiratory function. The result of the experiment showed that it was easier to maintain a large and stable thoracic ROM during deep breathing by using the real-time visual biofeedback system of the thoracic ROM.

[Cost-effectiveness in Dutch mental health care: future because of ROM?

NARCIS (Netherlands)

Agthoven, M. van; Kolk, A. van der; Knegtering, H.; Delespaul, P.A.; Arends, J.; Jeurissen, P.P.T.; Krabbe, P.F.M.; Huijsman, R.; Luijk, R.; Beurs, E. de; Hakkaart-van Roijen, L.; Bruggeman, R.

2015-01-01

BACKGROUND: The document reporting Dutch mental health care negotiations for 2014 - 2017 calls for a cost decrease based on cost-effectiveness. Thanks to rom, the Dutch mental health care seems well prepared for cost-effectiveness research.
AIM: Evaluate how valid cost-effectiveness research

Regional Ocean Modeling System (ROMS): CNMI

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Regional Ocean Modeling System (ROMS) 7-day, 3-hourly forecast for the region surrounding the Commonwealth of the Northern Mariana Islands (CNMI) at approximately...

Regional Ocean Modeling System (ROMS): Samoa

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Regional Ocean Modeling System (ROMS) 7-day, 3-hourly forecast for the region surrounding the islands of Samoa at approximately 3-km resolution. While considerable...

Regional Ocean Modeling System (ROMS): Guam

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Regional Ocean Modeling System (ROMS) 6-day, 3-hourly forecast for the region surrounding Guam at approximately 2-km resolution. While considerable effort has been...

Regional Ocean Modeling System (ROMS): Oahu

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Regional Ocean Modeling System (ROMS) 7-day, 3-hourly forecast for the region surrounding the island of Oahu at approximately 1-km resolution. While considerable...

Nanomechanical recognition of prognostic biomarker suPAR with DVD-ROM optical technology

DEFF Research Database (Denmark)

Bache, Michael; Bosco, Filippo; Brøgger, Anna Line

2013-01-01

In this work the use of a high-throughput nanomechanical detection system based on a DVD-ROM optical drive and cantilever sensors is presented for the detection of urokinase plasminogen activator receptor inflammatory biomarker (uPAR). Several large scale studies have linked elevated levels...

Fabrication of CdS/CdTe-Based Thin Film Solar Cells Using an Electrochemical Technique

Directory of Open Access Journals (Sweden)

I. M. Dharmadasa

2014-06-01

Full Text Available Thin film solar cells based on cadmium telluride (CdTe are complex devices which have great potential for achieving high conversion efficiencies. Lack of understanding in materials issues and device physics slows down the rapid progress of these devices. This paper combines relevant results from the literature with new results from a research programme based on electro-plated CdS and CdTe. A wide range of analytical techniques was used to investigate the materials and device structures. It has been experimentally found that n-, i- and p-type CdTe can be grown easily by electroplating. These material layers consist of nano- and micro-rod type or columnar type grains, growing normal to the substrate. Stoichiometric materials exhibit the highest crystallinity and resistivity, and layers grown closer to these conditions show n → p or p → n conversion upon heat treatment. The general trend of CdCl2 treatment is to gradually change the CdTe material’s n-type electrical property towards i-type or p-type conduction. This work also identifies a rapid structural transition of CdTe layer at 385 ± 5 °C and a slow structural transition at higher temperatures when annealed or grown at high temperature. The second transition occurs after 430 °C and requires more work to understand this gradual transition. This work also identifies the existence of two different solar cell configurations for CdS/CdTe which creates a complex situation. Finally, the paper presents the way forward with next generation CdTe-based solar cells utilising low-cost materials in their columnar nature in graded bandgap structures. These devices could absorb UV, visible and IR radiation from the solar spectrum and combine impact ionisation and impurity photovoltaic (PV effect as well as making use of IR photons from the surroundings when fully optimised.

Validation of accuracy and reliability of a simple measurement device for the lumber range of motion (SMD-L-ROM)

International Nuclear Information System (INIS)

Kato, Nakayuki; Fujiwara, Atsushi; Honda, Toshio; Taneichi, Hiroshi

2007-01-01

It is important to evaluate mobility of the lumbar spine for assessment of lumbar spinal disorders and their therapeutic effects. We developed a simple measurement device for the lumbar range of motion (SMD-L-ROM) which can be installed on the trunk. SMD-L-ROM allows to evaluate mobility of the lumbar spine without x-ray exposure. Accuracy and reliability of the measurement device was assessed in this article. SMD-L-ROM comprises two metallic immobilization plates (IPs) with a vertically installed bar and a rubber band for fixation of IP to the trunk. Two IPs were installed at the level of Th12 and the sacrum. Range of motion (ROM) of the lumbar spine was measured by using SMD-L-ROM and radiographic modalities (X-ray and CT). Consistency of the measured values by both of SMD-L-ROM and radiographic modalities was evaluated. Furthermore, inter- and intra-observer agreement of measured values by SMD-L-ROM was assessed. Regarding measurement of ROM, there was a high correlation between SMD-L-ROM and X-ray/CT especially in the sagittal and axial plane. There was no significant difference in the average values of ROM between the two methods. On the other hand, SMD-L-ROM did not detect accurate position of the lumbar spine in all dimensions. There were no inter- and intra-observer errors of measured values by SMD-L-ROM. ROM of the lumbar spine was simply and economically measured with SMD-L-ROM. Accuracy and reliability of SMD-L-ROM was good enough for ROM measurement in the lumbar spine. (author)

An Interactive Multimedia Based Instruction in Experimental Modelling

DEFF Research Database (Denmark)

Knudsen, Morten; Nielsen, J.N.; Østergaard, J.

1997-01-01

A CD-ROM based interactive multimedia instruction in experimental modelling for Danish Engineering School teachers is described. The content is based on a new sensitivity approach for direct estimation of physical parameters in linear and nonlinear dynamic systems. The presentation is inspired of...... of Solomans=s inventory of learning styles. To enhance active learning and motivation by real life problems, the simulation tool Matlab is integrated in the authoring program Medi8or....

CARA MUDAH MENYIAPKAN MATERI PEMBELAJARAN BERBASIS WEB DAN CD UNTUK BAHASA INDONESIA

Directory of Open Access Journals (Sweden)

Yusring Sanusi Baso

2015-04-01

Full Text Available Revolution of Information and Communication Technology (ICT has changed the various areas of human life, including the revolution in education. Revolution of education occurs since people migrate their way of learning from conventional to digital learning, face-to-face at a certain time and place into a meeting from anywhere and anytime. In the past we used paper, now we already headed to paperless era. Several years ago, teachers and lecturers is the source of knowledge, it is the source of knowledge can be through a variety of media, such as CD-ROMs and the Internet. The way we learn is change to distant learning with free study hour. Then, it results the term e-learning, knowledge server and knowledge based society. This article discusses how to prepare simple e-learning material (web and cd-based about Bahasa Indonesian. The program that employs to elaborate and modify the material is Hot Potatoes which is published by the University of Victoria and the Half-Baked Software. The material of Bahasa Indonesian use in this program is a set of questions on National Examination for Selection Admissions (SPMB. These questions will create an interactive multimedia material, especially web-based and CD-based material. Modules that are discussed in this article including input of data (questions, answers, etc., output configuration (modification of the display and apperance, as well as techniques to publish on the website. In addition, it will also discuss how to keep the material in the web and cd. The final result (output or material output from this program is the material that can be used as in learning Bahasa Indonesian, especially for self training and test. The Output will be in the form of website and CDs. Keywords: e-learning, Hot Potatoes, web and cd.

Nanoscale Relationship Between CD4 and CD25 of T Cells Visualized with NSOM/QD-Based Dual-Color Imaging System

Science.gov (United States)

Fan, Jinping; Lu, Xiaoxu; Liu, Shengde; Zhong, Liyun

2015-10-01

In this study, by using of near-field scanning optical microscopy (NSOM)/immune-labeling quantum dot (QD)-based dual-color imaging system, we achieved the direct visualization of nanoscale profiles for distribution and organization of CD4 and CD25 molecules in T cells. A novel and interesting finding was that though CD25 clustering as nanodomains were observed on the surface of CD4+CD25high regulatory T cells, these CD25 nanodomains were not co-localized with CD4 nanodomains. This result presented that the formation of these CD25 nanodomains on the surface of CD4+CD25high T cells were not associated with the response of T cell receptor (TCR)/CD3-dependent signal transduction. In contrast, on the surface of CD4+CD25low T cells, CD25 molecules distributed randomly without forming nanodomains while CD4 clustering as nanodomains can be observed; on the surface of CD8+CD25+ T cells, CD25 clustering as nanodomains and co-localization with CD8 nanodomains were observed. Collectively, above these results exhibited that TCR/CD3-based microdomains were indeed required for TCR/CD3-mediated T cells activation and enhanced the immune activity of CD4+CD25low T cells or CD8+CD25+ T cells. In particular, it was found that the formation of CD25 nanodomains and their segregation from TCR/CD3 microdomains were the intrinsic capability of CD4+CD25high T cells, suggesting this specific imaging feature of CD25 should be greatly associated with the regulatory activity of CD4+CD25high T cells. Importantly, this novel NSOM/QD-based dual-color imaging system will provide a useful tool for the research of distribution-function relationship of cell-surface molecules.

Molecular Cloning, Expression and Characterization of Plasmid Encoding Rhomboid 4 (ROM4 of Tachyzoite of Toxoplasma gondii RH Strain

Directory of Open Access Journals (Sweden)

Mohammad Taghi RAHIMI

2017-12-01

Full Text Available AbstractBackground: The objective of this study was to clone, express and characterize the gene encoding rhomboid 4 (ROM4 proteins, a vital gene in surface adhesion and host cell invasion process of tachyzoite of T. gondii in an appropriate expression vector and eukaryotic cell for production of recombinant protein.Methods: Toxoplasma RNA was isolated from tachyzoites (RH strain and complementary DNA was synthesized. Oligonucleotide primer pair was designed based on Toxoplasma ROM4 gene sequence with XhoI and EcoRI restriction sites at 5´ end of forward and reverse primers, respectively. ROM4 gene was amplified by PCR, cloned into pTG19-T vector and the recombinant plasmid was sequenced. The gene was subcloned into pcDNA3 plasmid and expressed in CHO cells as eukaryotic cell. SDS-PAGE and western blotting were performed for protein determination and verification.Results: Cloning of ROM4 gene in pTG19-T vector was confirmed by colony-PCR and enzymatic digestion. The results of enzymatic digestion and gene sequencing confirmed successful cloning and subcloning procedures. The nucleotide sequence of the cloned ROM4 gene showed 99% homology compared to the corresponding sequences of original gene. SDS-PAGE and western blotting analyses of the purified protein revealed a single band having expected size of 65 kDa.Conclusion: This eukaryotic expression system is an appropriate system for high-level recombinant protein production of ROM4 gene from T. gondii tachyzoites used as antigenic component for serological assay and vaccine development.

A multimedia package for particle technology

International Nuclear Information System (INIS)

Mathers, B.; Rhodes, M.; Iveson, S.

2002-01-01

A CD-ROM-based package is being prepared for Particle Technology education. It is based on the textbook 'Introduction to Particle Technology' by Martin Rhodes, and aims to expand on the information given in the text by making best possible use of the advantages offered by the CD-ROM format, including use of videos, animations and interactive functions. The CD-ROM will be divided into the same twelve sections as the text. Each section will have subsections of: 1) Industrial Relevance (showing a video and/or photos and explanation of how the subject matter is used in industry). 2) Experiment/Demonstration (a video where measurements can be taken by the user, or explanatory video and raw data provided. The user will be given directions on how to carry out the experiment and the necessary calculations). 3) Quiz (multiple choice format testing the knowledge gained in the previous sections). 4) Calculators (allowing the user to easily make important particle technology calculations) The CD-ROM will allow users the opportunity to observe particulate processes and operations without the necessity of participating in laboratories or site visits, and will therefore be a useful tool for distance education, for users learning on an individual basis or as an addition to institutionally based particle technology courses

Operating Experience with Nuclear Power Stations in Member States in 2011. 2012 Edition (CD-ROM)

International Nuclear Information System (INIS)

2012-08-01

This CD contains the 43rd edition of the IAEA's series of annual reports on operating experience with nuclear power plants in Member States. It is a direct output from the IAEA's Power Reactor Information System (PRIS) and contains information on electricity production and overall performance of individual operational plants during 2011. In addition to annual information, the report contains a historical summary of performance during the lifetime of individual plants and figures illustrating worldwide performance of the nuclear industry. The CD contains also an overview of design characteristics and dashboards of all operating nuclear power plants worldwide.

Novel CD7-specific nanobody-based immunotoxins potently enhanced apoptosis of CD7-positive malignant cells.

Science.gov (United States)

Tang, Jinle; Li, Jialu; Zhu, Xuejun; Yu, Yuan; Chen, Dan; Yuan, Lei; Gu, Zhenyang; Zhang, Xingding; Qi, Lin; Gong, Zhishu; Jiang, Pengjun; Yu, Juhua; Meng, Huimin; An, Gangli; Zheng, Huyong; Yang, Lin

2016-06-07

Various CD7-targeting immunotoxins have been tested for its potential in treating CD7+ malignant patients but none of those immunotoxins was approved clinically because of lacking enough efficacy and safety. Here we successfully constructed the monovalent and bivalent CD7 nanobody-based immunotoxins PG001 and PG002, both conjugated with a truncated derivative of Pseudomonas exotoxin A respectively. The prokaryotic system expressed immunotoxins not only maintained their binding specificity for CD7-positive cells with a Kd of 16.74 nM and 3.6 nM for PG001 and PG002 respectively, but also efficiently promoted antigen-restricted apoptosis of the CD7-positive leukemia cell lines Jurkat and CEM, and primary T-cell acute lymphoblastic leukemia (T-ALL) and acute myeloid leukemia (AML) cells with an in vitro cytotoxic activity (EC50) in the range of 23-30 pM for PG002. In NOD/SCID mice transplanted with CEM cells, PG001 and PG002 prevented engraftment of the cells and markedly prolonged mouse survival. Owing to the efficient antigen-restricted anti-leukemic activity of PG002, this CD7 nanobody-based immunotoxin exhibited a superior anti-CD7 positive malignancies activity than previously reported immunotoxins, and may represent a promising therapeutic strategy in treating CD7-positive leukemia and lymphoma, which still remain a significant clinical challenge.

Intertekstualitāte Dž.K. Roulingas "Harija Potera" romānu serijā

OpenAIRE

Strunga-Raude, Aija

2009-01-01

Šī bakalaura darba tēma ir „Intertekstualitāte Dž. K. Roulingas "Harija Potera" romānu sērijā”. Es izvēlējos šo tēmu, jo 2008. gadā tika izdota pēdējā septītā grāmata šajā romānu sērijā un šīs grāmatas jau ir izraisījušas plašas diskusijas dažādās sabiedrības grupās. Šī ir lieliska iespēja izpētīt ko tieši Džoanna Ketlīna Roulinga ir izmantojusi savā romānā “Harijs Poters”. Šī darba mērķis ir ilustrēt kā Dž. K. Roulinga, rakstot „Harija Potera” romānu sēriju, ir izmantojusi intertekstualit...

Comparative investigation of toxicity and bioaccumulation of Cd-based quantum dots and Cd salt in freshwater plant Lemna minor L.

Science.gov (United States)

Modlitbová, Pavlína; Novotný, Karel; Pořízka, Pavel; Klus, Jakub; Lubal, Přemysl; Zlámalová-Gargošová, Helena; Kaiser, Jozef

2018-01-01

The purpose of this study was to determine the toxicity of two different sources of cadmium, i.e. CdCl 2 and Cd-based Quantum Dots (QDs), for freshwater model plant Lemna minor L. Cadmium telluride QDs were capped with two coating ligands: glutathione (GSH) or 3-mercaptopropionic acid (MPA). Growth rate inhibition and final biomass inhibition of L. minor after 168-h exposure were monitored as toxicity endpoints. Dose-response curves for Cd toxicity and EC50 168h values were statistically evaluated for all sources of Cd to uncover possible differences among the toxicities of tested compounds. Total Cd content and its bioaccumulation factors (BAFs) in L. minor after the exposure period were also determined to distinguish Cd bioaccumulation patterns with respect to different test compounds. Laser-Induced Breakdown Spectroscopy (LIBS) with lateral resolution of 200µm was employed in order to obtain two-dimensional maps of Cd spatial distribution in L. minor fronds. Our results show that GSH- and MPA-capped Cd-based QDs have similar toxicity for L. minor, but are significantly less toxic than CdCl 2 . However, both sources of Cd lead to similar patterns of Cd bioaccumulation and distribution in L. minor fronds. Our results are in line with previous reports that the main mediators of Cd toxicity and bioaccumulation in aquatic plants are Cd 2+ ions dissolved from Cd-based QDs. Copyright © 2017 Elsevier Inc. All rights reserved.

Regional Ocean Modeling System (ROMS): Main Hawaiian Islands

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Regional Ocean Modeling System (ROMS) 7-day, 3-hourly forecast for the region surrounding the main Hawaiian islands at approximately 4-km resolution. While...

Regional Ocean Modeling System (ROMS): CNMI: Data Assimilating

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Regional Ocean Modeling System (ROMS) 3-day, 3-hourly data assimilating hindcast for the region surrounding the Commonwealth of the Northern Mariana Islands (CNMI)...

Regional Ocean Modeling System (ROMS): Samoa: Data Assimilating

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Regional Ocean Modeling System (ROMS) 3-day, 3-hourly data assimilating hindcast for the region surrounding the islands of Samoa at approximately 3-km resolution....

Regional Ocean Modeling System (ROMS): Oahu: Data Assimilating

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Regional Ocean Modeling System (ROMS) 2-day, 3-hourly data assimilating hindcast for the region surrounding the island of Oahu at approximately 1-km resolution....

A. Moerdijk en R. Tempelaars (redactie). Van A tot Z en verder ...

African Journals Online (AJOL)

rbr

op CD-ROM en elektroniese databasisse as redes vir sy optimistiese toekoms- perspektief. Volgens Moerdijk kan die leemtes wat in die gedrukte weergawe van die. WNT voorkom, aangevul word met die elektroniese weergawe wat in 1995 op. CD-ROM verskyn het. Deur gebruik te maak van die CD-ROM is aanvullende.

Regional Ocean Modeling System (ROMS): Oahu South Shore

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Regional Ocean Modeling System (ROMS) 2-day, 3-hourly forecast for the region surrounding the south shore of the island of Oahu at approximately 200-m resolution....

Between Freedom and Constraint: ROM Hacking of Pokémon Games

OpenAIRE

Barnabé, Fanny

2018-01-01

This paper aims to study a creative practice widespread in video game cultures: “ROM hacking”. By examining with the tools of rhetoric a defined corpus of ROM hacks derived from 『Pokémon』 games, the presentation will show that the formal construction of these derivative works demonstrates less a free or subversive transformation than a fairly strict respect for the original games’ conventions. By reproducing the structure of official 『Pokémon 』games, these fan productions become mirrors revea...

Admittance of MIS-Structures Based on HgCdTe with a Double-Layer CdTe/Al2O3 Insulator

Science.gov (United States)

Dzyadukh, S. M.; Voitsekhovskii, A. V.; Nesmelov, S. N.; Sidorov, G. Yu.; Varavin, V. S.; Vasil'ev, V. V.; Dvoretsky, S. A.; Mikhailov, N. N.; Yakushev, M. V.

2018-03-01

Admittance of MIS structures based on n( p)- Hg1-xCdxTe (at x from 0.22 to 0.40) with SiO2/Si3N4, Al2O3, and CdTe/Al2O3 insulators is studied experimentally at 77 K. Growth of an intermediate CdTe layer during epitaxy results in the almost complete disappearance of the hysteresis of electrophysical characteristics of MIS structures based on graded-gap n-HgCdTe for a small range of the voltage variation. For a wide range of the voltage variation, the hysteresis of the capacitance-voltage characteristics appears for MIS structures based on n-HgCdTe with the CdTe/Al2O3 insulator. However, the hysteresis mechanism differs from that in case of a single-layer Al2O3 insulator. For MIS structures based on p-HgCdTe, introduction of an additional CdTe layer does not lead to a significant decrease of the hysteresis phenomena, which may be due to the degradation of the interface properties when mercury leaves the film as a result of low-temperature annealing changing the conductivity type of the semiconductor.

Development and Utilization of Regional Oceanic Modeling System (ROMS) & Delicacy, Imprecision, and Uncertainty of Oceanic Simulations: An Investigation with ROMS

Science.gov (United States)

2010-09-30

and Ecosystems: An important community use for ROMS is biogeochemisty: chemical cycles, water quality, blooms , micro-nutrients, larval dispersal... Chile current system. J. Climate, submitted. Colas, F., X. Capet, and J. McWilliams, 2010b: Mesoscale eddy buoyancy flux and eddy-induced

Ģimene Mārgaretas Atvudas romānos

OpenAIRE

Voitiņa, Laura

2009-01-01

Mūsdienās diskusijas par ģimeni, tās vērtībām, mainīgo uzbūvi un problēmām, kas ietekmē šo institūtu, ir sastopamas ne tikai mutvārdu runā, bet arī rakstos. Dotā pētījuma mērķis bija veikt saturisku analīzi par ģimenes aprakstiem Margaretas Atvudas romānos “Istabenes Stāsts” un “Oriksa un Kreiks”, lai identificētu romānos aprakstītos ģimenes modeļus, vērtības, paražas un notikumus, kas ietekmē šo institūtu. Tika izmantotas gan teorētiskas, gan empīriskas pētījuma metodes. Lai sniegtu teorētis...

Recent state of CdTe-based radiation detectors

International Nuclear Information System (INIS)

Ohno, R.

2004-01-01

Recent state for development of CdTe-based radiation detectors is reviewed. The progress of the technologies such as the crystal growth of CdTe and CdZnTe, the deposition of electrodes on the crystal, the design of read out ASIC, and the bonding between crystal and ASIC, opened the way for the development of imaging devices for practical uses. A X-ray imager for non destructive inspections and a gamma ray imager for small animal radioisotope experiments or nuclear medicine are presented as examples. (author)

Fluorescence turn-on sensing of trace cadmium ions based on EDTA-etched CdTe@CdS quantum dot.

Science.gov (United States)

Wang, Si-Nan; Zhu, Jian; Li, Xin; Li, Jian-Jun; Zhao, Jun-Wu

2018-05-01

Cadmium-caused environmental pollution and diseases have always been worldwide problems. Thus it is extremely urgent to establish a cheap, rapid, simple and selective detection method for trace cadmium in drinking water. In this study, a fluorescence "turn-on" method based on ethylene diamine tetraacetic acid (EDTA)-etched CdTe@CdS quantum dots (QDs) was designed to detect Cd 2+ . High resolution transmission electron microscopy (HRTEM) and X-ray photoelectron spectroscopy (XPS) were utilized for chemical and structural characterization of the as-prepared QDs. Based on chemical etching of EDTA on the surface of CdTe@CdS QDs, specific Cd 2+ recognition sites were produced, and then results in fluorescence quenching. The introduction of Cd 2+ could identify these sites and restore the fluorescence of the EDTA-QDs system. Under the optimum conditions, the nanoprobe shows a linear response range from 0.05 to 9 μM with a very low detection limit of 0.032 μM. In addition, the reported fluorescence probe in this work displays a good selectivity for trace Cd 2+ over other metal ions and an admirable practicability in real water samples. Copyright © 2018 Elsevier B.V. All rights reserved.

SSTL I/O Standard Based Environment Friendly Energy Efficient ROM Design on FPGA

DEFF Research Database (Denmark)

Bansal, Neha; Bansal, Meenakshi; Saini, Rishita

2014-01-01

are operating ROM with the highest operating frequency of 4th generation i7 processor to test the compatibility of this design with the latest hardware in use. When there is no demand of peak performance, then we can save 74.5% clock power, 75% signal power, and 30.83% I/O power by operating our device with 1......Stub Series Terminated Logic (SSTL) is an Input/output standard. It is used to match the impedance of line, port and device of our design under consideration. Therefore, selection of energy efficient SSTL I/O standard among available different class of SSTL logic family in FPGA, plays a vital role...

En teoretisk utdyping av rom og materialitet som pedagogisk ressurs i barnehagen

Directory of Open Access Journals (Sweden)

Solveig Nordtømme

2015-07-01

Full Text Available Abstract: This article is a theoretical exploration with the aim of discussing an ontological basis for space and materiality as educational resources in kindergarten. Attention is directed on children’s play experiences interacting with space and materiality, and how children use and create space. The metaphors front stage, space in between, and backstage (inspired from Erving Goffman, 1969, which form the study's main findings, are used as the backdrop for the issue and analyzes. The empirical material used in this exploration has been collected with an ethnographic methodological approach in two kindergartens. Maurice Merleau-Ponty’s (1962 focus on bodily experience and presence in space, along with concepts from Latour’s (2005 actor-network theory, is used to explore the data. The article contributes with theoretical tools for professionals in kindergarten teaching, to shed light on the importance of space, materiality and play in children's everyday life in kindergarten.Sammendrag: Denne artikkelen diskuterer et ontologisk grunnlag og er en teoretisk utforskning av rom og materialitet som en pedagogisk ressurs i barnehagen. Oppmerksomheten er rettet mot barns lekeerfaringer i samspill med rom og materialitet, og hvordan barn bruker og skaper rom. Metaforene hovedrom, mellomrom, og bakrom (inspirert fra Erving Goffman, 1969, som danner studiens hovedfunn, blir brukt som et bakteppe for problemstilling og analyser av det empiriske materialet fra to barnehager. Maurice Merleau-Ponty publikasjoner The Phenomenology of Perception (Merleau-Ponty, 1962 med sitt fokus på kroppslig erfaring i levd rom, blir brukt sammen med begreper fra Latours aktør-nettverksteori (Latour 2005 til å utforske hvordan rom og materialitet kan være pedagogiske ressurser. Artikkelens kunnskapsbidrag er å presentere et teoretisk verktøy for barnehageprofesjonen og kunnskaper om lekens betydning i barns hverdag i barnehagen.

Is there a role for rifampicin, ofloxacin and minocycline (ROM) therapy in the treatment of leprosy? Systematic review and meta-analysis.

Science.gov (United States)

Setia, Maninder S; Shinde, Santosh S; Jerajani, Hemangi R; Boivin, Jean-François

2011-12-01

A combination of rifampicin, ofloxacin and minocycline (ROM) is one of the newer recommendations for treatment of leprosy. We performed a systematic review and a meta-analysis of studies that had evaluated the efficacy of ROM therapy in treatment of paucibacillary and multibacillary leprosy patients. Studies were identified by searching the PubMed, Embase, LILACS and Cochrane databases. Data were abstracted from all relevant studies, and fixed effects models were used to calculate the summary estimate of effect in paucibacillary and multibacillary leprosy patients. Six studies comparing ROM therapy to multidrug therapy and eight studies that evaluated the effect of ROM therapy alone (no comparison group) were included in the review and meta-analysis. The combined estimate for single dose ROM vs. multidrug therapy in paucibacillary leprosy patients suggested that ROM was less effective than multidrug therapy in these patients [relative risk: 0.91, 95% confidence intervals (CI): 0.86-0.97]. However, the combined estimate for multiple doses of ROM vs. multidrug therapy in multibacillary leprosy patients suggested that ROM was as effective as multidrug therapy in reducing bacillary indices in these patients (proportion change: -4%, 95% CI -31% to 23%). No major side effects were reported in either the ROM or the multidrug treatment groups. Single-dose ROM therapy was less effective than multidrug therapy in paucibacillary patients. However, there are insufficient data to come to a valid conclusion on the efficacy of multidose ROM therapy in multibacillary leprosy, and additional studies with ROM therapy in multibacillary leprosy are needed. Furthermore, multiple doses may be considered as another alternative even for paucibacillary patients, and randomised controlled trials of this therapy may be useful to understand its contribution in the treatment and control of leprosy. © 2011 Blackwell Publishing Ltd.

Calculation method of passive tracer using regional ocean modeling system (ROMS)

International Nuclear Information System (INIS)

Tubono, Takaki; Tsumune, Daisuke; Misumi, Kazuhiro; Yoshida, Yoshikatsu

2010-01-01

A dose assessments method for packages shipping radioactive materials was developed to calculate concentrations of radioactive materials discharged from the hypothetically sinking point using Regional Ocean Modeling System (ROMS). The programs of ROMS were improved for simultaneously calculating the flow fields around Japan and the concentrations discharged from several bottom points in the continental shelf. The model domain covered the northeast pacific region around Japan, 20degN-65degN, 120degE-165degE, with 1/10 degree horizontal resolution and 30 sigma-levels. The ROMS model captured main features such as Kuroshio currents, including the separation location and the Kuroshio extension, and Oyashio currents. The calculated volume transports through the main straits such as Tokara strait, Tsushima strait and Tsugaru strait were compared well to the measured or estimated that. The calculated concentrations discharged from 12 bottom points showed mixing associated with the eddies of ocean currents. This method is available to evaluate effectively the concentrations of radioactive materials only by setting the subsidence location and the concentrations and volume discharged. (author)

Fine mapping of Best`s macular dystrophy localises the gene in close proximity to, but distinct from, the D115480/ROM1

Energy Technology Data Exchange (ETDEWEB)

Graff, C.; Ahlbom, B.E.; Anneren, G. [University Hospital, Uppsala (Sweden)] [and others

1994-09-01

Best`s macular dystrophy (BMD) is an autosomal dominant disease characterized by accumulation of lipofuscin beneath the pigment epithelium of the macula, leading to early-onset impairment of central vision. The gene has previously been mapped to 11q13. Based on DNA from 191 people from a large 12-generation family, the gene now has been mapped to a 1.5 cM interval between the markers Fc{epsilon}RI and D11S480/ROM1. By disequilibrium analysis the gene was estimated to be 0.321 cM centromeric to the marker D11S480. Since this on average corresponds to 300 kb, the gene may be at a distance contained in YAC molecules. To physically characterize this region, YAC clones positive for markers flanking BMD have been identified. Sequence analysis of the candidate gene ROM1 did not reveal any mutation. However, one recombination between intragenic ROM1 polymorphisms and BMD was detected, which make it highly unlikely that mutations in ROM1 are causing BMD.

The Application of a Modified d-ROMs Test for Measurement of Oxidative Stress and Oxidized High-Density Lipoprotein

Directory of Open Access Journals (Sweden)

Fumiaki Ito

2017-02-01

Full Text Available Reactive oxygen species (ROS are involved in the initiation and progression of atherosclerosis. ROS-derived hydroperoxides, as an indicator of ROS production, have been measured by using the diacron reactive oxygen metabolites (d-ROMs test, which requires iron-containing transferrin in the reaction mixture. In this study we developed a modified d-ROMs test, termed the Fe-ROMs test, where iron ions were exogenously added to the reaction mixture. This modification is expected to exclude the assay variation that comes from different blood iron levels in individuals. In addition, this Fe-ROMs test was helpful for determining the class of plasma lipoproteins that are hydroperoxidized. Low-density lipoprotein/very low-density lipoprotein (LDL/VLDL and high-density lipoprotein (HDL were purified by use of an LDL/VLDL purification kit and the dextran sulfate-Mg2+ precipitation method, respectively; their hydroperoxide contents were assessed by performing the Fe-ROMs test. The majority of the hydroperoxides were detected only in the HDL fraction, not in the LDL/VLDL. Further detailed analysis of HDLs by size-exclusion high-performance liquid chromatography revealed that the hydroperoxide-containing molecules were small-sized HDLs. Because HDL was shown to be the principal vehicle for the plasma hydroperoxides, this Fe-ROMs test is a beneficial method for the assessment of oxidized-HDL levels. Indeed, Fe-ROMs levels were strongly associated with the levels of oxidized HDL, which were determined by performing the malondialdehyde-modified HDL enzyme immunoassay. In conclusion, the Fe-ROMs test using plasma itself or the HDL fraction after dextran sulfate-Mg2+ precipitation is useful to assess the functionality of HDL, because the oxidation of HDL impairs its antiatherogenic capacity.

CD20-based Immunotherapy of B-cell Derived Hematologic Malignancies.

Science.gov (United States)

Shanehbandi, Dariush; Majidi, Jafar; Kazemi, Tohid; Baradaran, Behzad; Aghebati-Maleki, Leili

2017-01-01

CD20 is a surface antigen, which is expressed at certain stages of B-cell differentiation. Targeting the CD20-positive B-cells with therapeutic monoclonal antibodies (MAbs) has been an effectual strategy in the treatment of hematologic malignancies such as non-Hodgkin's lymphoma (NHL) and chronic lymphocytic leukemia (CLL). Initial success with Rituximab (RTX) has encouraged the creation and development of more effective CD20 based therapeutics. However, treatment with conventional MAbs has not been adequate to overcome the problems such as refractory/ relapsed disease. In this regard, new generations of MAbs with enhanced affinity or improved anti-tumor properties have been developed. CD20 directed therapeutics have heterogeneous features and mechanisms of action. Hence, having sufficient knowledge on the immunological and molecular aspects of CD20 based cancer therapy is necessary for predicting the clinical outcomes and taking the necessary measures. An extensive search was performed in PubMed and similar databases for peer-reviewed articles concerning the biology, function and characteristics of CD20 molecule as well as the mechanisms of action and evolutionary process of CD20 targeting agents. This review provides information about the current situation of CD20 targeting immunotherapeutics including MAbs, bispecific antibodies (which exert multiple functions or involve Tcells in tumor elimination) and CAR T-cells (engineered T-cells armed with chimeric antigen receptors). Moreover, limitations, challenges and available solutions regarding the application of CD20 targeting treatments are addressed. Utilization of CD20-targeted therapeutics, due to their diverse properties, requires special considerations. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Manufacturing process of rewritable CD and DVD; Kakikae gata CD, DVD no seizo process

Energy Technology Data Exchange (ETDEWEB)

Horie, M. [Mitsubishi Chemical Corp., Tokyo (Japan)

1998-11-05

Development of rewritable DVD is desired which has feedback compatibility with the existing players and ROM drives. The DVD is formed on a substrate with a thickness of 0.6 mm (dummy plate), and is composed of the multilayer film, i.e., protective coating made of UV hardening resin, reflective layer, dielectric protective layer, phase change type recording layer, and polycarbonate layer from the lower in order. A pair of dummy plates are pasted to enhance the mechanical strength, which has the same thickness of 1.2 mm as CD. Since the grooves and prepits are very fine, injection molding is more difficult compared with CD. Since a great stress change occurs during the formation and initialization processes of multilayer of phase change recording medium layer which is particular to DVD manufacturing process, control of warping is significant. Control of warping of the substrate is also significant, which affects the pasting and the whole process. The recording layer, dielectric protective layer and reflective layer are formed by the discharge spattering. The initialization is a particular process to the phase change medium. Complete non-recording state can be obtained by crystallizing the amorphous recording layer after the film formation. 3 figs.

Adolescencia, relaciones románticas y actividad sexual: una revisión

OpenAIRE

Vargas Trujillo, Elvia; Barrera, Fernando

2008-01-01

Se presenta una revisión de algunas de las investigaciones más recientes sobre la adolescencia y los factores asociados a las relaciones románticas y la actividad sexual durante la adolescencia. Se parte de la premisa de que el análisis de la iniciación romántica y sexual durante la adolescencia requiere de modelos de causalidad múltiple que permitan dar cuenta, conjuntamente, de los factores que se encuentran en los contextos individual, familiar y social asociados con estos dos procesos. Se...

Experimental study on x-rays dose enhancement effects for floating gate ROMs

CERN Document Server

Guo Hong Xia; Chen Yu Sheng; Han Fu Bin; He Chao Hui; Zhao Hui

2002-01-01

Experimental results of x-ray dose enhancement effects are given for floating gate read-only memory (ROMs) irradiated in the Beijing Synchrotron Radiation Facility. The wrong byte numbers vs. total irradiation dose have been tested and the equivalent relation of total dose damage is provided compared the response of devices irradiated with sup 6 sup 0 Co gamma-ray source. The x-ray dose enhancement factors for floating gate ROMs are obtained firstly in China. These results can be an effective evaluation data for x-rays radiation hardening technology

CD-SEM real time bias correction using reference metrology based modeling

Science.gov (United States)

Ukraintsev, V.; Banke, W.; Zagorodnev, G.; Archie, C.; Rana, N.; Pavlovsky, V.; Smirnov, V.; Briginas, I.; Katnani, A.; Vaid, A.

2018-03-01

Accuracy of patterning impacts yield, IC performance and technology time to market. Accuracy of patterning relies on optical proximity correction (OPC) models built using CD-SEM inputs and intra die critical dimension (CD) control based on CD-SEM. Sub-nanometer measurement uncertainty (MU) of CD-SEM is required for current technologies. Reported design and process related bias variation of CD-SEM is in the range of several nanometers. Reference metrology and numerical modeling are used to correct SEM. Both methods are slow to be used for real time bias correction. We report on real time CD-SEM bias correction using empirical models based on reference metrology (RM) data. Significant amount of currently untapped information (sidewall angle, corner rounding, etc.) is obtainable from SEM waveforms. Using additional RM information provided for specific technology (design rules, materials, processes) CD extraction algorithms can be pre-built and then used in real time for accurate CD extraction from regular CD-SEM images. The art and challenge of SEM modeling is in finding robust correlation between SEM waveform features and bias of CD-SEM as well as in minimizing RM inputs needed to create accurate (within the design and process space) model. The new approach was applied to improve CD-SEM accuracy of 45 nm GATE and 32 nm MET1 OPC 1D models. In both cases MU of the state of the art CD-SEM has been improved by 3x and reduced to a nanometer level. Similar approach can be applied to 2D (end of line, contours, etc.) and 3D (sidewall angle, corner rounding, etc.) cases.

Associative conceptual space-based information retrieval systems

NARCIS (Netherlands)

M.J. Schuemie (Martijn); J.H. van den Berg (Jan)

1998-01-01

textabstractIn this `Information Era' with the availability of large collections of books, articles, journals, CD-ROMs, video films and so on, there exists an increasing need for intelligent information retrieval systems that enable users to find the information desired easily. Many attempts have

Regional Ocean Modeling System (ROMS): Main Hawaiian Islands: Data Assimilating

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — Regional Ocean Modeling System (ROMS) 3-day, 3-hourly data assimilating hindcast for the region surrounding the main Hawaiian islands at approximately 4-km...

An end-to-end coupled model ROMS-N 2 P 2 Z 2 D 2 -OSMOSE of ...

African Journals Online (AJOL)

An end-to-end coupled model ROMS-N 2 P 2 Z 2 D 2 -OSMOSE of the southern Benguela foodweb: parameterisation, calibration and pattern-oriented validation. ... We also highlight the capacity of this model for tracking indicators at various hierarchical levels. Keywords: individual-based model, model validation, ...

Tidal simulation using regional ocean modeling systems (ROMS)

Science.gov (United States)

Wang, Xiaochun; Chao, Yi; Li, Zhijin; Dong, Changming; Farrara, John; McWilliams, James C.; Shum, C. K.; Wang, Yu; Matsumoto, Koji; Rosenfeld, Leslie K.;

ZnS-Passivated CdSe/CdS Co-sensitized Mesoporous Zn2SnO4 Based Solar Cells

International Nuclear Information System (INIS)

Kim, Kyungho; Park, Ji Eun; Park, Eun Su; Park, Yun Chang; Kim, Joosun; Im, Chan; Lee, Man-Jong

2014-01-01

Graphical abstract: - Highlights: • Mesoporous Zn 2 SnO 4 sensitized by CdSe/CdS QDs were synthesized via a two-step sequential process. • Assembled QDs were characterized by HRTEM and STEM mapping. • Efficiency increase in CdSe/CdS co-sensitized Zn 2 SnO 4 DSSCs is discussed. • The role of ZnS passivation layer is discussed by impedance spectroscopy. - Abstract: CdS and CdSe/CdS quantum dot (QD) sensitizers were assembled onto mesoporous ternary Zn 2 SnO 4 photoanodes using a two-step sequential process of successive ionic layer absorption and reaction (SILAR) and chemical bath deposition (CBD) for QD-cosensitized solar cell applications. The assembled CdS and CdSe QDs were observed using high-angle annular dark-field scanning transmission electron microscopy (HAADF-STEM), high-resolution TEM (HRTEM), and STEM/energy-dispersive X-ray spectroscopy (EDS) elemental mapping. CdSe/CdS cosensitized Zn 2 SnO 4 -based cells showed a higher absorption onset position, a stepwise band-edge level alignment, and, thereby, an improved power conversion efficiency (PCE) of 1.628% under one-sun conditions, which is the best result obtained using mesoporous Zn 2 SnO 4 reported to date. In addition, the effect of a ZnS passivation layer on the photovoltaic performance and aging behavior has been investigated. Electrochemical impedance spectroscopy (EIS) showed that the main role of the ZnS layer is to enhance the aging behavior of the CdSe/CdS/Zn 2 SnO 4 cells by improving the electron lifetime and charge recombination

Significance of measuring oxidative stress in lifestyle-related diseases from the viewpoint of correlation between d-ROMs and BAP in Japanese subjects

International Nuclear Information System (INIS)

Fukui, Toshiki; Yamauchi, Kazuhiro; Maruyama, Mie; Yasuda, Tadashi; Abe, Youichi; Kohno, Masakazu

2011-01-01

In recent years, oxidative stress has been postulated to be an important factor in the pathogenesis and development of lifestyle-related diseases. In this study, we investigated the association between the derivatives of reactive oxygen metabolites (d-ROMs), as an index of products of reactive oxygen species (ROS), and biological antioxidant potential (BAP), as an index of antioxidant potential. We also investigated the associations between d-ROMs or BAP and the risk factors for lifestyle-related diseases or metabolic syndrome-associated factors to evaluate their usefulness in preventive medicine. There were 442 subjects who underwent health checkup examination in our facilities. In addition to standard medical checkup items, we analyzed d-ROMs, BAP, brachial-ankle pulse wave velocity, high-sensitivity C-reactive protein level and visceral fat area (VFA) visualized on a computed tomography scan. The mean d-ROM value in females was significantly higher than that in males. There was a positive correlation between the d-ROM and VFA levels. On correlation analysis, there was a negative correlation between the d-ROM and creatinine levels. As factors that influence d-ROMs, the level of VFA was selected, suggesting the significance of oxidative stress measurement with d-ROMs. In addition, there was a positive correlation between d-ROMs and BAP values. Further research is required to resolve whether increased production of ROS or the antioxidant potential that can compensate for such an increase of ROS is more important in vivo. (author)

Alois Riegl, Die Entstehung der Barockkunst in Rom, 1908

NARCIS (Netherlands)

Witte, A.; Bacchi, A.; Barroero, L.

2017-01-01

In 1908, Alois Riegl's unfinished text on the Italian Baroque was published by Max Dvorak and Arthur Burda; they edited part of his notes for three consecutive series of lectures at Vienna University. Riegl's book title aply reads Entstehung der Barockkunst in Rom: Akademische Vorlesungen and deals

CO-CD base management model of Universitas Terbuka community service program

Science.gov (United States)

Kridasakti, S. W.; Sudirah; Siregar, H.

2018-03-01

These studies were to respond whether the UT social-aid management had been executed under CO-CD principles (Ife J. 1995) and what CO-CD base community service management model can be built. The goals of these evaluational studies were UT social-aid managerial performance profile (2011-2013) and CO-CD management model development. The methods used were Survey and FGD. For data collection were involving the UT officers, the counterparts, and the documents. The analysis used combination between the Performance Analysis (Irawan P., 2003) and the CIPP (Stuffelbeam, D, L., & Shinkfield, A, J., 1985). The findings showed that the quantitative targeting in program completion was credible in achievement (85%). However, the “qulitative targeting” of the management goals was indicating far from a good-stage (≤5.0_Interval-Force: 1-10 Scale). The “Gap” was due to the absent of socialization_needs-analysis_maintenance_release factors on the UT social-service grand-policy. The trial of CO-CD Base Management Model had been imposed to the community that turned out to be very effective to self-help, and the ensuing SOP had been successfully defined. Conclusion, ‘CO-CD Principles’ were not designed in UT community service programs management. However, if efficiency and effectivity likely to be achieved, the SOP of ‘CO-CD Base Management Model has to be adopted.

[Does routine outcome monitoring have a promising future? An investigation into the use of shared decision-making combined with ROM for patients with a combination of physical and psychiatric symptoms].

Science.gov (United States)

van der Feltz-Cornelis, C M; Andrea, H; Kessels, E; Duivenvoorden, H J; Biemans, H; Metz, M

2014-01-01

Although routine outcome monitoring (ROM) has been developed and widely used in the course of patient centered outcome research in the Netherlands, so far the technique has hardly ever been used to improve the treatment of individual patients. To describe how a rom technique based on the principles of shared decision-making (SDM) was developed and evaluated at the Center for Body, Mind and Health at GGz Breburg, a specialised mental health institution in the Netherlands. We have developed a conceptual model for SDM that involves patient participation and the use of evidence-based decision-aids with cut-off scores. According to the conceptual model for SDM that we developed, the patient and the health professional involved took 'shared' decisions in three phases; the decisions related to triage, the drawing-up of a treatment plan and a follow-up treatment course. At the end of the 6 month intake-phase 7 of the 67 patients who were deemed eligible for ROM/SDM were dropped from the study because they were incapable of performing ROM assessments. Due to diagnostic advice and referral at the end of the intake-phase, 25 patients did not require further treatment. Of the remaining 35 patients, 33 delivered at least one follow-up ROM assessment during the subsequent treatment phases. In these patients somatic and psychiatric symptoms were found to be significantly reduced. ROM combined with sdm can be used successfully with patients who have a combination of physical and psychiatric symptoms and the technique can be applied by the professional in charge. Very few patients dropped out of the follow-up measurements and somatic as well as depressive or psychiatric symptoms diminished significantly. These findings indicate that a Randomised Clinical Trial is warranted in order to test the effectiveness of sdm combined with ROM as a decision-making instrument.

Low-Cost Lattice Matching Si Based Composite Substrates for HgCdTe

Science.gov (United States)

2013-09-01

211). ..............................................5 Figure 3. Relationship between calculated alloy compositions based on Se/CdTe BEP ratio and...Se:CdTe beam equivalent pressure ( BEP ) ratios. During CdSeTe growth, Se and Te are in competition for the same nucleation sites. If we assume that all...therefore, x(cal) = ΦSe/ΦCd = 2ΦSe/ΦCdTe, where Φ is the BEP of the material, measured by the nude ion gauge at the substrate position. Figure 3 shows the

Electrochemiluminescence Biosensor Based on Thioglycolic Acid-Capped CdSe QDs for Sensing Glucose

Directory of Open Access Journals (Sweden)

Eun-Young Jung

2016-01-01

Full Text Available In order to detect low level glucose concentration, an electrochemiluminescence (ECL biosensor based on TGA-capped CdSe quantum dots (QDs was fabricated by the immobilization of CdSe QDs after modifying the surface of a glassy carbon electrode (GCE with 4-aminothiophenol diazonium salts by the electrochemical method. For the detection of glucose concentration, glucose oxidase (GOD was immobilized onto the fabricated CdSe QDs-modified electrode. The fabricated ECL biosensor based on TGA-capped CdSe QDs was characterized using a scanning electron microscope (SEM, UV-vis spectrophotometry, transmission electron microscopy (TEM, a fluorescence spectrometer (PL, and cyclic voltammetry (CV. The fabricated ECL biosensor based on TGA-capped CdSe QDs is suitable for the detection of glucose concentrations in real human blood samples.

Polarographic study of Cd(II)-Schiff base complexes and d.m.e. menthanol-water medium

International Nuclear Information System (INIS)

Patel, M.S.; Trivedi, T.; Vyas, D.N.

1978-01-01

Three Schiff base complexes of Cd 2+ have been investigated polarographically in 60% menthanol-water medium at 26 0 C. The Schiff bases used are salicyladehyde tris buffer (ST), benzaldehydetris buffer (BT) and vanillin tris buffer (VT). Cd-ST and Cd-VT complexes produce reversible reduction wave at dme, while Cd-BT gives a quasi reversible wave. Stability constants of the complexes have been determined and the standard overall electrode reaction rate constant (ksub(e)sup(o)) B of the Cd-BT complex is determined by three different methods. The log β values of complexes are : Cd-ST, 2.72; Cd-VT, 4.90; and Cd-BT, 4.41. (author)

The Correlation of Exercise and Range of Motion (ROM on Elderly Knee Observasional Study on Elderly People in Pedurungan Semarang

Directory of Open Access Journals (Sweden)

Adhitya Putra Widyantoro

2012-06-01

Design and Method: Observastional study with a cross sectional design 80 elderly men and women were divided into 2 groups: gymnastics group in the Social Rehabilitation Unit Of Pucang Gading (n=40 and unexcercises group in the Penggaron village (n=40. In both groups, the degree of ROM of knee was assessed using the Goniometer. To evaluate the value of its significance, the data were analyzed using the Mann Withney test followed by Spearmann’s rho test. Result: ROM for gymnastic(exercised group and unexercised group were 115.50°±11.591°, 95.38°±12.780° respectively with p<0. 001. Resuts showed that doing exercise was useful for maintaining ROM of knee in elderly people. Spearmann’s rho test resulted in a strong correlation between ROM and exercise with r value of 0.652. Conclusion: exercise correlates with ROM of knee in elderly (Sains Medika, 4(1:39-45.

Laser-induced luminescence of multilayer structures based on polyimides and CdSe and CdSe/ZnS nanocrystals

International Nuclear Information System (INIS)

Chistyakov, A A; Dayneko, S V; Zakharchenko, K V; Kolesnikov, V A; Tedoradze, M G; Mochalov, K E; Oleinikov, V A

2009-01-01

Laser-induced luminescence of multilayer structures based on the solids of CdSe and CdSe/ZnS nanocrystals, different organic semiconductors and on the layers of organic semiconductors with embedded nanocrystals has been investigated. Drastic decrease of luminescence quantum yield is observed in the films of CdSe nanocrystals on organic semiconductors compared to those on optical glasses. The luminescence of the nanocrystals in the matrices of organic semiconductors and in multilayer structures is shown to be suppressed. The effects observed are explained by the transfer of photogenerated carriers from the nanocrystals to the molecules of organic semiconductors. The presence of the charge transfer is confirmed by a drastic increase in the conductivity (by 2 – 4 orders of magnitude) and in photovoltaic effect at the presence of CdSe and CdSe/ZnS nanocrystals in the structures under investigation. The prospects of using the multilayer structures for development new materials for solar cells are discussed

NODC Standard Product: Atlas of surface marine data 1994 (9 disc set) (NCEI Accession 0101474)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — A set of 9 CD-ROMs were produced to accompany the analog publication Atlas of Surface Marine Data, 1994. Each CD-ROM contains monthly mean objectively analyzed...

Development and Utilization of Regional Oceanic Modeling System (ROMS). Delicacy, Imprecision, and Uncertainty of Oceanic Simulations: An Investigation with the Regional Oceanic Modeling System (ROMS). Mixing in the Ocean Surface Layer Using the Regional Oceanic Modeling System (ROMS).

Science.gov (United States)

2011-09-30

community use for ROMS is biogeochemisty: chemical cycles, water quality, blooms , micro-nutrients, larval dispersal, biome transitions, and coupling to...J.C. McWilliams, X. Capet, and J. Kurian, 2010: Heat balance and eddies in the Peru- Chile Current System. Climate Dynamics, 37, in press. doi10.1007

Biblioteca Naţională a României: obiective şi perspective în valorificarea patrimoniului cultural

Directory of Open Access Journals (Sweden)

Elena Tîrziman

2008-01-01

Biblioteca Naţională a României este implicată în proiecte internaţionale care au ca scop crearea de conţinut digital relevant pentru memoria culturală europeană: The European Library – TEL (Biblioteca europeană, Manuscriptorium şi ENRICH – European Networking Resources and Information concerning Cultural Heritage, proiecte coordonate de Biblioteca Naţională a Cehiei. Biblioteca Naţională a României a contribuit la proiectele Manuscriptorium / ENRICH prin carte românească veche din perioada corespunzătoare secolelor XVI-XVII.

IAEA fast reactor knowledge preservation initiative. Project focus: KNK-II reactor, Karlsruhe, Germany

International Nuclear Information System (INIS)

2004-08-01

This Working Material (including the attached CD-ROM) documents progress made in the IAEA's initiative to preserve knowledge in the fast reactor domain. The brochure describes briefly the context of the initiative and gives an introduction to the contents of the CD-ROM. In 2003/2004 a first focus of activity was concentrated on the preservation of knowledge related to the KNK-II experimental fast reactor in Karlsruhe, Germany. The urgency of this project was given by the impending physical destruction of the installation, including the office buildings. Important KNK-II documentation was brought to safety and preserved just in time. The CD-ROM contains the full texts of 264 technical and scientific documents describing research, development and operating experience gained with the KNK-II installation over a period of time from 1965 to 2002, extending through initial investigations, 17 years of rich operating experience, and final shutdown and decommissioning. The index to the documents on the CD-ROM is printed at the end of this booklet in chronological order and is accessible on the CD by subject index and chronological index. The CD-ROM contains in its root directory also the document 'fr c lassification.pdf' which describes the classification system used for the present collection of documents on the fast reactor KNK-II

"Reagent-free" L-asparaginase activity assay based on CD spectroscopy and conductometry.

Science.gov (United States)

Kudryashova, Elena V; Sukhoverkov, Kirill V

2016-02-01

A new method to determine the catalytic parameters of L-asparaginase using circular dichroism spectroscopy (CD spectroscopy) has been developed. The assay is based on the difference in CD signal between the substrate (L-asparagine) and the product (L-aspartic acid) of enzymatic reaction. CD spectroscopy, being a direct method, enables continuous measurement, and thus differentiates from multistage and laborious approach based on Nessler's method, and overcomes limitations of conjugated enzymatic reaction methods. In this work, we show robust measurements of L-asparaginase activity in conjugates with PEG-chitosan copolymers, which otherwise would not have been possible. The main limitation associated with the CD method is that the analysis should be performed at substrate saturation conditions (V max regime). For K M measurement, the conductometry method is suggested, which can serve as a complimentary method to CD spectroscopy. The activity assay based on CD spectroscopy and conductometry was successfully implicated to examine the catalytic parameters of L-asparaginase conjugates with chitosan and its derivatives, and for optimization of the molecular architecture and composition of such conjugates for improving biocatalytic properties of the enzyme in the physiological conditions. The approach developed is potentially applicable to other enzymatic reactions where the spectroscopic properties of substrate and product do not enable direct measurement with absorption or fluorescence spectroscopy. This may include a number of amino acid or glycoside-transforming enzymes.

Electro chemiluminescence Biosensor Based on Thioglycolic Acid-Capped Cd Se QDs for Sensing Glucose

International Nuclear Information System (INIS)

Jung, E. Y.; Ye, J. H.; Choi, S. H.; Jung, S. H.

2016-01-01

In order to detect low level glucose concentration, an electro chemiluminescence (ECL) biosensor based on TGA-capped Cd Se quantum dots (QDs) was fabricated by the immobilization of Cd Se QDs after modifying the surface of a glassy carbon electrode (GCE) with 4-amino thiophenol diazonium salts by the electrochemical method. For the detection of glucose concentration, glucose oxidase (GOD) was immobilized onto the fabricated Cd Se QDs-modified electrode. The fabricated ECL biosensor based on TGA-capped Cd Se QDs was characterized using a scanning electron microscope (SEM), UV-vis spectrophotometry, transmission electron microscopy (TEM), a fluorescence spectrometer (PL), and cyclic voltammetry (CV). The fabricated ECL biosensor based on TGA-capped Cd Se QDs is suitable for the detection of glucose concentrations in real human blood samples.

Geology and resource assessment of Costa Rica at 1:500,000 scale; a digital representation of maps of the U.S. Geological Survey's 1987 folio I-1865

Science.gov (United States)

Schruben, Paul G.

1997-01-01

This CD-ROM contains digital versions of the geology and resource assessment maps of Costa Rica originally published in USGS Folio I-1865 (U.S. Geological Survey, the Direccion General de Geologia, Minas e Hidrocarburos, and the Universidad de Costa Rica, 1987) at a scale of 1:500,000. The following layers are available on the CD-ROM: geology and faults; favorable domains for selected deposit types; Bouguer gravity data; isostatic gravity contours; mineral deposits, prospects, and occurrences; and rock geochemistry sample points. For DOS users, the CD-ROM contains MAPPER, a user-friendly map display program. Some of the maps are also provided in the following additional formats on the CD-ROM: (1) ArcView 1 and 3, (2) ARC/INFO 6.1.2 Export, (3) Digital Line Graph (DLG) Optional, and (4) Drawing Exchange File (DXF.)

An ultrasensitive hydrogen peroxide biosensor based on electrocatalytic synergy of graphene-gold nanocomposite, CdTe-CdS core-shell quantum dots and gold nanoparticles

International Nuclear Information System (INIS)

Gu Zhiguo; Yang Shuping; Li Zaijun; Sun Xiulan; Wang Guangli; Fang Yinjun; Liu Junkang

2011-01-01

Graphical abstract: We first reported an ultrasensitive hydrogen peroxide biosensor in this work, which was fabricated by coating graphene-gold nanocomposite, CdTe-CdS core-shell quantum dots, gold nanoparticles and horseradish peroxidase in sequence on the surface of gold electrode. Since a promising their electrocatalytic synergy towards hydrogen peroxide was achieved, the biosensor displayed very high sensitivity, low detection limit (S/N = 3) (3.2 x 10 -11 M) and good long-term stability (20 weeks). Highlights: · We for the first time integrated novel hydrogen peroxide biosensor based on G-AuNP, CdTe-CdS and AuNPs. · Three nanomaterials show remarkable synergistic electrocatalysis towards hydrogen peroxide. · The biosensor provides the best sensitivity in all biosensors based on graphene for detection of glucose up to now. - Abstract: We first reported an ultrasensitive hydrogen peroxide biosensor in this work. The biosensor was fabricated by coating graphene-gold nanocomposite (G-AuNP), CdTe-CdS core-shell quantum dots (CdTe-CdS), gold nanoparticles (AuNPs) and horseradish peroxidase (HRP) in sequence on the surface of gold electrode (GE). Cyclic voltammetry and differential pulse voltammetry were used to investigate electrochemical performances of the biosensor. Since promising electrocatalytic synergy of G-AuNP, CdTe-CdS and AuNPs towards hydrogen peroxide was achieved, the biosensor displayed a high sensitivity, low detection limit (S/N = 3) (3.2 x 10 -11 M), wide calibration range (from 1 x 10 -10 M to 1.2 x 10 -8 M) and good long-term stability (20 weeks). Moreover, the effects of omitting G-AuNP, CdTe-CdS and AuNP were also examined. It was found that sensitivity of the biosensor is more 11-fold better if G-AuNP, CdTe-CdS and AuNPs are used. This could be ascribed to improvement of the conductivity between graphene nanosheets in the G-AuNP due to introduction of the AuNPs, ultrafast charge transfer from CdTe-CdS to the graphene sheets and AuNP due to

Solar cells based on electrodeposited thin films of ZnS, CdS, CdSSe and CdTe

Science.gov (United States)

Weerasinghe, Ajith R.

The motivations of this research were to produce increased efficiency and low-cost solar cells. The production efficiency of Si solar cells has almost reached their theoretical limit, and reducing the manufacturing cost of Si solar cells is difficult to achieve due to the high-energy usage in material purifying and processing stages. Due to the low usage of materials and input energy, thin film solar cells have the potential to reduce the costs. CdS/CdTe thin film solar cells are already the cheapest on $/W basis. The cost of CdTe solar cells can be further reduced if all the semiconducting layers are fabricated using the electrodeposition (ED) method. ED method is scalable, low in the usage of energy and raw materials. These benefits lead to the cost effective production of semiconductors. The conventional method of fabricating CdS layers produces Cd containing waste solutions routinely, which adds to the cost of solar cells.ZnS, CdS and CdS(i-X)Sex buffer and window layers and CdTe absorber layers have been successfully electrodeposited and explored under this research investigation. These layers were fully characterised using complementary techniques to evaluate the material properties. Photoelectrochemical (PEC) studies, optical absorption, X-ray diffraction (XRD), X-ray fluorescence (XRF), scanning electron microscopy (SEM), energy-dispersive X-ray (EDX) spectroscopy, atomic force microscopy (AFM) and Raman spectroscopy were utilised to evaluate the material properties of these solid thin film layers. ZnS and CdS thin film layers were electrodeposited from Na-free chemical precursors to avoid the group I element (Na) to reduce deterioration of CdTe devices. Deposition parameters such as, growth substrates, temperature, pH, growth cathodic voltage, stirring rate, time and chemical concentrations were identified to fabricate the above semiconductors. To further optimise these layers, a heat treatment process specific to the material was developed. In addition

Improved photoluminescence quantum yield and stability of CdSe-TOP, CdSe-ODA-TOPO, CdSe/CdS and CdSe/EP nanocomposites

Science.gov (United States)

Wei, Shutian; Zhu, Zhilin; Wang, Zhixiao; Wei, Gugangfen; Wang, Pingjian; Li, Hai; Hua, Zhen; Lin, Zhonghai

2016-07-01

Size-controllable monodisperse CdSe nanocrystals with different organic capping were prepared based on the hot-injection method. The effective separation of nucleation and growth was achieved by rapidly mixing two highly reactive precursors. As a contrast, we prepared CdSe/CdS nanocrystals (NCs) successfully based on the selective ion layer adsorption and reaction (SILAR) technique. This inorganic capping obtained higher photoluminescence quantum yield (PLQY) of 59.3% compared with organic capping of 40.8%. Furthermore, the CdSe-epoxy resin (EP) composites were prepared by adopting a flexible ex situ method, and showed excellent stability in the ambient environment for one year. So the composites with both high PLQY of nanocrystals and excellent stability are very promising to device application.

A Community Terrain-Following Ocean Modeling System (ROMS)

Science.gov (United States)

2015-09-30

funded NOPP project titled: Toward the Development of a Coupled COAMPS-ROMS Ensemble Kalman filter and adjoint with a focus on the Indian Ocean and the...surface temperature and surface salinity daily averages for 31-Jan-2014. Similarly, Figure 3 shows the sea surface height averaged solution for 31-Jan... temperature (upper panel; Celsius) and surface salinity (lower panel) for 31-Jan-2014. The refined solution for the Hudson Canyon grid is overlaid on

DICOM-compliant PACS with CD-based image archival

Science.gov (United States)

Cox, Robert D.; Henri, Christopher J.; Rubin, Richard K.; Bret, Patrice M.

1998-07-01

This paper describes the design and implementation of a low- cost PACS conforming to the DICOM 3.0 standard. The goal was to provide an efficient image archival and management solution on a heterogeneous hospital network as a basis for filmless radiology. The system follows a distributed, client/server model and was implemented at a fraction of the cost of a commercial PACS. It provides reliable archiving on recordable CD and allows access to digital images throughout the hospital and on the Internet. Dedicated servers have been designed for short-term storage, CD-based archival, data retrieval and remote data access or teleradiology. The short-term storage devices provide DICOM storage and query/retrieve services to scanners and workstations and approximately twelve weeks of 'on-line' image data. The CD-based archival and data retrieval processes are fully automated with the exception of CD loading and unloading. The system employs lossless compression on both short- and long-term storage devices. All servers communicate via the DICOM protocol in conjunction with both local and 'master' SQL-patient databases. Records are transferred from the local to the master database independently, ensuring that storage devices will still function if the master database server cannot be reached. The system features rules-based work-flow management and WWW servers to provide multi-platform remote data access. The WWW server system is distributed on the storage, retrieval and teleradiology servers allowing viewing of locally stored image data directly in a WWW browser without the need for data transfer to a central WWW server. An independent system monitors disk usage, processes, network and CPU load on each server and reports errors to the image management team via email. The PACS was implemented using a combination of off-the-shelf hardware, freely available software and applications developed in-house. The system has enabled filmless operation in CT, MR and ultrasound within

Planar heterojunction perovskite solar cell based on CdS electron transport layer

KAUST Repository

Abulikemu, Mutalifu

2017-07-02

We report on planar heterojunction perovskite solar cells employing a metal chalcogenide (CdS) electron transport layer with power conversion efficiency up to 10.8%. The CdS layer was deposited via solution-process chemical bath deposition at low-temperature (60°C). Pinhole-free and uniform thin films were obtained with good structural, optical and morphological properties. An optimal layer thickness of 60nm yielded an improved open-circuit voltage and fill factor compared to the standard TiO2-based solar cells. Devices showed a higher reproducibility of the results compared to TiO2-based ones. We also tested the effect of annealing temperature on the CdS film and the effect of CdCl2 treatment followed by high temperature annealing (410°C) that is expected to passivate the surface, thus eliminating eventual trap-states inducing recombination.

Planar heterojunction perovskite solar cell based on CdS electron transport layer

KAUST Repository

Abulikemu, Mutalifu; Barbe, Jeremy; El Labban, Abdulrahman; Eid, Jessica; Del Gobbo, Silvano

2017-01-01

We report on planar heterojunction perovskite solar cells employing a metal chalcogenide (CdS) electron transport layer with power conversion efficiency up to 10.8%. The CdS layer was deposited via solution-process chemical bath deposition at low-temperature (60°C). Pinhole-free and uniform thin films were obtained with good structural, optical and morphological properties. An optimal layer thickness of 60nm yielded an improved open-circuit voltage and fill factor compared to the standard TiO2-based solar cells. Devices showed a higher reproducibility of the results compared to TiO2-based ones. We also tested the effect of annealing temperature on the CdS film and the effect of CdCl2 treatment followed by high temperature annealing (410°C) that is expected to passivate the surface, thus eliminating eventual trap-states inducing recombination.

Arquitectura románica en la provincia de Soria, 1856-2014. Marco historiográfico y metodológico

Directory of Open Access Journals (Sweden)

Lorenzo Arribas, Josemi

2014-12-01

Full Text Available The historiography of Romanesque in the province of Soria has three different stages. The former one begins with Eduardo Saavedra’s researches (1856 and it extends until 1934, when Gaya Nuño defends his PhD Thesis (La arquitectura románica en la provincia de Soria, which will not be published until 1946. The Spanish Civil War and the post-war period mark the beginning of the second stage, which is merely transitional, lacking any important contribution. The last stage begins with the publication of the three volumes of the Enciclopedia del Románico en Castilla y León (2002. These works have largely improved the knowledge of Romanesque architectural heritage, enhanced besides by the task undertaken by the technical office of the Cultural Project Soria Románica (2007- 2012, responsible for studying and restoring more than thirty Romanesque buildings in the Southern part of province. It is within this working frame that the building recording of the churches here presented must be understood. This historiographical assessment about provincial Romanesque does not include those buildings sited in the capital city, the Cathedral of El Burgo de Osma, the Monastery of Santa Maria de Huerta and the hermitage of San Baudelio (Casillas de Berlanga.La historiografía del Románico en la provincia de Soria tiene tres etapas diferenciadas. Una inicial, que parte de los estudios de Eduardo Saavedra (1856 y se extiende hasta 1934, fecha de la lectura de la tesis doctoral de Gaya Nuño (La arquitectura románica en la provincia de Soria, cuya publicación, no obstante, se demora hasta 1946. La Guerra Civil y posguerra marcan el comienzo de la segunda etapa, transicional y sin grandes aportaciones. La última etapa se inaugura con la publicación de los tres volúmenes sorianos de la Enciclopedia del Románico en Castilla y León (2002. Esta obra ha multiplicado el conocimiento del patrimonio edilicio románico, acrecentado, después, por la labor de la

Fabrication of fluorescence-based biosensors from functionalized CdSe and CdTe quantum dots for pesticide detection

International Nuclear Information System (INIS)

Chi Tran, Thi Kim; Vu, Duc Chinh; Thuy Ung, Thi Dieu; Nguyen, Hai Yen; Nguyen, Ngoc Hai; Dao, Tran Cao; Pham, Thu Nga; Nguyen, Quang Liem

2012-01-01

This paper presents the results on the fabrication of highly sensitive fluorescence biosensors for pesticide detection. The biosensors are actually constructed from the complex of quantum dots (QDs), acetylcholinesterase (AChE) and acetylthiocholine (ATCh). The biosensor activity is based on the change of luminescence from CdSe and CdTe QDs with pH, while the pH is changed with the hydrolysis rate of ATCh catalyzed by the enzyme AChE, whose activity is specifically inhibited by pesticides. Two kinds of QDs were used to fabricate our biosensors: (i) CdSe QDs synthesized in high-boiling non-polar organic solvent and then functionalized by shelling with two monolayers (2-ML) of ZnSe and eight monolayers (8-ML) of ZnS and finally capped with 3-mercaptopropionic acid (MPA) to become water soluble; and (ii) CdTe QDs synthesized in aqueous phase then shelled with CdS. For normal checks the fabricated biosensors could detect parathion methyl (PM) pesticide at very low contents of ppm with the threshold as low as 0.05 ppm. The dynamic range from 0.05 ppm to 1 ppm for the pesticide detection could be expandable by increasing the AChE amount in the biosensor. (paper)

Uudiseid ja meeldetuletusi raamatukogult / Karin Tulve

Index Scriptorium Estoniae

Tulve, Karin

2000-01-01

2000. aastast on TPÜ raamatukokku ostetud EBSCO online andmebaasid, augustist on võimalik kasutada referaat- ja täistekstandmebaasi Academic Search FullText International 15 CD-ROM-il ja septembrist humanitaarteaduste bibliograafilist andmebaasi Sophia : European Databases in the Humanities CD-ROM-il

NODC Standard Product: International ocean atlas Volume 11 - Climatic atlas of the Sea of Azov 2008 (1 disc set) (NODC Accession 0098574)

Data.gov (United States)

National Oceanic and Atmospheric Administration, Department of Commerce — This Atlas, Climatic Atlas of the Sea of Azov 2008 on CD-ROM, is an update to Volume 10, Climatic Atlas of the Sea of Azov 2006 on CD-ROM (NODC Accession 0098572),...

Experimental study on gamma irradiation effects of floating gate ROMs The ROM is stated for Read-only Memory

CERN Document Server

He Chao Hui; Chen Xiao Hua; Wang Yan Ping; Peng Hong Lun

2002-01-01

Experimental results of gamma irradiation effects are given for Floating gate ROMs. There is an accumulated dose threshold. Errors occur when accumulated dose is above the threshold, no error occurs when below the threshold. The errors go up with the increase of the accumulated dose. Errors occur in devices that are measured during irradiation and irradiated in power on, moreover, new data cannot be written in these devices with programmer. However, under more accumulated dose, there is no error in devices in power off mode and new data can be written in these devices with programmer

Task-shifting of CD4 T cell count monitoring by the touchscreen-based Muse™ Auto CD4/CD4% single-platform system for CD4 T cell numeration: Implication for decentralization in resource-constrained settings.

Science.gov (United States)

Kouabosso, André; Mossoro-Kpinde, Christian Diamant; Bouassa, Ralph-Sydney Mboumba; Longo, Jean De Dieu; Mbeko Simaleko, Marcel; Grésenguet, Gérard; Bélec, Laurent

2018-04-01

The accuracy of CD4 T cell monitoring by the recently developed flow cytometry-based CD4 T cell counting Muse™ Auto CD4/CD4% Assay analyzer (EMD Millipore Corporation, Merck Life Sciences, KGaA, Darmstadt, Germany) was evaluated in trained lay providers against laboratory technicians. After 2 days of training on the Muse™ Auto CD4/CD4% analyzer, EDTA-blood samples from 6 HIV-positive and 4 HIV-negative individuals were used for CD4 T cell counting in triplicate in parallel by 12 trained lay providers as compared to 10 lab technicians. Mean number of CD4 T cells in absolute number was 829 ± 380 cells/μl by lay providers and 794 ± 409 cells/μl by technicians (P > 0.05); and in percentage 36.2 ± 14.8%CD4 by lay providers and 36.1 ± 15.0%CD4 by laboratory technician (P > 0.05). The unweighted linear regression and Passing-Bablok regression analyses on CD4 T cell results expressed in absolute count revealed moderate correlation between CD4 T cell counts obtained by lay providers and lab technicians. The mean absolute bias measured by Bland-Altman analysis between CD4 T cell/μl obtained by lay providers and lab technicians was -3.41 cells/μl. Intra-assay coefficient of variance (CV) of Muse™ Auto CD4/CD4% in absolute number was 10.1% by lay providers and 8.5% by lab technicians (P > 0.05), and in percentage 5.5% by lay providers and 4.4% by lab technicians (P > 0.05). The inter-assay CV of Muse™ Auto CD4/CD4% in absolute number was 13.4% by lay providers and 10.3% by lab technicians (P > 0.05), and in percentage 7.8% by lay providers and 6.9% by lab technicians (P > 0.05). The study demonstrates the feasibility of CD4 T cell counting using the alternative flow cytometer Muse™ Auto CD4/CD4% analyzer by trained lay providers and therefore the practical possibility of decentralization CD4 T cell counting to health community centers. Copyright © 2018. Published by Elsevier B.V.

Fabrication and characterization of Ag-Cd/CdO materials produced by incorporation of CdO particles to liquid Ag-Cd alloys; Fabricacion y caracterizacion de materiales Ag-Cd/CdO producidos mediante incorporacion de particulas de CdO en aleaciones Ag-Cd liquidas

Energy Technology Data Exchange (ETDEWEB)

Equihua-Guillen, F.; Ruiz-Mondragon, J.; Servin-Castaneda, R.; Orozco-Gonzalez, P.; Zaldivar-Cadena, A.; Martinez-Villafane, F.; Villarreal-Garza, E. J.

2014-04-01

In the present work it has been investigated the kinetic behavior of internal oxidation processes of strips of Ag-Cd/CdO materials fabricated by adding CdO particles (size of 5 and 20 {mu}m) in liquid Ag-Cd alloys. It has been established the metallurgical mechanism that controls the formation of the thickness covered with CdO particles produced by internal oxidation of the Ag-Cd/CdO material. It has been developed, successfully, a metallographic preparation technique for characterizing the morphology, size and distribution of CdO particles produced by heat treatment of internal oxidation on the surface of each sample based on the distance from the original surface to the boundary of dispersed CdO particles. The material strips were sequentially roughed on its surface and the roughing thickness was measured in the cross section of each new surface to determine the number of particles per area and average particle size. (Author)

Optical sensor based on a single CdS nanobelt.

Science.gov (United States)

Li, Lei; Yang, Shuming; Han, Feng; Wang, Liangjun; Zhang, Xiaotong; Jiang, Zhuangde; Pan, Anlian

2014-04-23

In this paper, an optical sensor based on a cadmium sulfide (CdS) nanobelt has been developed. The CdS nanobelt was synthesized by the vapor phase transportation (VPT) method. X-Ray Diffraction (XRD) and Transmission Electron Microscopy (TEM) results revealed that the nanobelt had a hexagonal wurtzite structure of CdS and presented good crystal quality. A single nanobelt Schottky contact optical sensor was fabricated by the electron beam lithography (EBL) technique, and the device current-voltage results showed back-to-back Schottky diode characteristics. The photosensitivity, dark current and the decay time of the sensor were 4 × 10⁴, 31 ms and 0.2 pA, respectively. The high photosensitivity and the short decay time were because of the exponential dependence of photocurrent on the number of the surface charges and the configuration of the back to back Schottky junctions.

Training project on Radiological Protection in medicine. Use of new technologies

International Nuclear Information System (INIS)

Ruis-Cruces, R.; Perez-Martinez, M.; Pastor Vega, J. M.; Diez de los Rios Delgado, A.

2003-01-01

Radiological protection training addressed to physicians should start during the teaching graduate and postgraduate studies, and a third phase only for those physicians using X rays and radioactive sources in diagnosis and treatment of diseases. To show a training project addressed to the teaching graduate students based on the new technologies, such as web online and interactive CD-ROM. Development of a web-online including information in.pdf (adobe acrobat) format and additional tools (as data bases, videos, news and class meetings, FAQ, tutorials). Moreover, we propose to development an interactive CD-ROM which will be used as a practical tool to complete the obligatory subject on radiological protection in the University of Malaga (Spain). We show the preliminary phase of the project. The web-online is being developed with the Microsoft FrontPage software. The first version of the CR-ROM is being developed in html format. These tools based on new technologies will be a very important support for radiological protection training, which is recommended by International Organizations (EC Report R116 and IAE Action Plan 2002-2006). (Author) 4 refs

Rapid assay of intrinsic radiosensitivity based on apoptosis in human CD4 and CD8 T-lymphocytes

International Nuclear Information System (INIS)

Ozsahin, Mahmut; Ozsahin, Huelya; Yuquan, Shi; Larsson, Boerje; Wuergler, Friedrich E.; Crompton, Nigel E. A.

1997-01-01

Purpose: An assay for radiosensitivity has numerous applications in the clinic. Avoidance of acute responses, prediction of normal tissue toxicity, and individualization of patient radiotherapy are included among these. We have developed a rapid assay (about 24 h) able to predict intrinsic radiosensitivity of CD4 and CD8 T-lymphocytes based on radiation-induced apoptosis. Methods and Materials: Fresh blood samples (1-2 ml in heparinized tubes) were irradiated with 0-, 2-, and 8-Gy X rays at a dose rate of approximately 3 Gy/min. Following irradiation, the cells were collected and prepared for flow-cytometric analysis and cell sorting. In conjunction with the CellQuest software available with the FACSVantage cell sorter (Becton-Dickinson), two T-lymphocyte types were analyzed on the basis of their cell-specific antigens (CD4 and CD8), and DNA was stained with DAPI. Following the separation of these cell types, radiation-induced cell death was assessed. Cytotoxicity was characterized by gradual degradation of internucleosomal DNA which results in a sub-G1 peak on the DNA histogram, and by the associated loss of surface antigens causing an intermediate positive peak in the antibody histogram. Using the assay, we investigated the interdonor variation in a cohort of 45 healthy adult blood donors and 5 children [one had immunodeficiency, centromeric instability, and facial anomalies syndrome (ICF), and one had ataxia telangiectasia (AT)]. Intradonor variation was assessed with 10 different experiments from a single donor. Results: CD4 and CD8 T-lymphocyte radiosensitivities were correlated (r 0.63 and 0.65 for 2 and 8 Gy, respectively) in 45 adult donors. Both for CD4 and CD8 cells, 2 and 8 Gy irradiation responses showed a good correlation (r 0.77 for both). Interdonor variation was significantly higher than intradonor variation (p < 0.0005) for all CD4 and CD8 data. We observed a decrease in the antigen fluorescence of dying cells, a phenomenon referred to as antigen

Evaluating an Interactive, Multimedia Education and Decision Program for Early-Stage Prostate Cancer Patients in a Randomized Controlled Trial

National Research Council Canada - National Science Library

Diefenbach, Michael A

2005-01-01

...). To educate patients about prostate cancer and its treatment and to ease their decisional burden, we have developed an innovative CD-ROM based multimedia prostate cancer interactive education system...

Micromechanical aptasensor-based protein detection using a compact-disc format microfluidics system

DEFF Research Database (Denmark)

Bosco, Filippo; Yang, J.; Chen, C. H.

2012-01-01

by optical readout heads from a DVD-ROM. The improved sensing platform facilitates measurements in continuous liquid flow with temperature control. Also, the wobbling of the CD platform has been reduced to a minimum and the scanning system has been optimized in order to detect cantilever deflections...

[Modern referral-information service in the Central Medical Library of the University of Zagreb Medical School].

Science.gov (United States)

Hadjina, G; Granić, D; Bekavac, A

1990-01-01

New technologies in information and retrieval services of the Central Medical Library are presented, as well as comparison between traditional search of biomedical literature and search of biomedical bases available on CD-ROM and on-line. MeSH thesaurus represents the basis for all modes of searches, either through published indexes (Index Medicus, Biomedicina Iugoslavica), searches through on-line, or via CD-ROM technology. Experience in indexing according to MeSH structure helps us to search and retrieve biomedical literature on new media too. Great interest in new media for search and retrieval of biomedical literature among our users (100%) justifies their introduction into the Library. In the period of four months, 75% of our users chose CD-ROM technology in their search, 25% chose on-line search, and both technologies were combined by 33% of the users. Having these new media in our library we have reached the point from which we join the world biomedical information network and successfully meet the growing need for information in the field of biomedicine.

Multimedia Materials for Language and Literacy Learning.

Science.gov (United States)

Hallett, Terry L.

1999-01-01

Introduces educators to inexpensive, commercially-available CD-ROM software that combines speech, text, graphics, sound, video, animation, and special effects that may be incorporated into classroom activities for both normally developing and language learning disabled children. Discusses three types of multimedia CD-ROM products: (1) virtual…

Expression of CD147 in advanced non-small cell lung cancer correlated with cisplatin-based chemotherapy resistance.

Science.gov (United States)

Zeng, H Z; Qu, Y Q; Liang, A B; Deng, A M; Zhang, W J; Xiu, B; Wang, H; Wang, H

2011-01-01

CD147, a widely expressed cell surface glycoprotein in cancer, is associated with tumor invasiveness and chemotherapy resistance. Recently, CD147 is also regarded as a potential therapeutic target for cancer therapy. The aim of the study was to investigate CD147 expression in non-small cell lung cancer (NSCLC), and evaluate its correlation with cisplatin-based chemotherapy resistance. In this study, we examined immunohistochemically the expression of CD147 in 118 advanced NSCLC cases treated with cisplatin-based chemotherapy, and then the association of CD147 expression with clinicopathological characteristics was analyzed. Furthermore, RNA interference approach was used to silence CD147 expression in a cisplatin-resistant human lung cancer cell line A549/DDP, and the inhibition effect of cisplatin on tumor cells was assayed by MTT. In the overall series, positive CD147 expression was observed in 101/118 (85.6%) cases. A membranous CD147 pattern was identified in 76/101 (75.2%) of CD147 positive tumors. CD147 membranous expression,but not the overall CD147 expression, was associated with poor response to cisplatin-based chemotherapies and a poor prognosis in advanced NSCLC patients. In vitro results showed that silencing CD147 increased the proliferation inhibitory effect of cisplatin to A549/DDP cells. In conclusion, our study indicated that membranous CD147 expression is a predictive factor of the response to cisplatin-based chemotherapies, and the use of CD147-targeted therapeutic adjuvants might be considered in the treatment of advanced NSCLC patients.

Optical Sensor Based on a Single CdS Nanobelt

Directory of Open Access Journals (Sweden)

Lei Li

2014-04-01

Full Text Available In this paper, an optical sensor based on a cadmium sulfide (CdS nanobelt has been developed. The CdS nanobelt was synthesized by the vapor phase transportation (VPT method. X-Ray Diffraction (XRD and Transmission Electron Microscopy (TEM results revealed that the nanobelt had a hexagonal wurtzite structure of CdS and presented good crystal quality. A single nanobelt Schottky contact optical sensor was fabricated by the electron beam lithography (EBL technique, and the device current-voltage results showed back-to-back Schottky diode characteristics. The photosensitivity, dark current and the decay time of the sensor were 4 × 104, 31 ms and 0.2 pA, respectively. The high photosensitivity and the short decay time were because of the exponential dependence of photocurrent on the number of the surface charges and the configuration of the back to back Schottky junctions.

Supraphysiologic control over HIV-1 replication mediated by CD8 T cells expressing a re-engineered CD4-based chimeric antigen receptor.

Directory of Open Access Journals (Sweden)

Rachel S Leibman

2017-10-01

Full Text Available HIV is adept at avoiding naturally generated T cell responses; therefore, there is a need to develop HIV-specific T cells with greater potency for use in HIV cure strategies. Starting with a CD4-based chimeric antigen receptor (CAR that was previously used without toxicity in clinical trials, we optimized the vector backbone, promoter, HIV targeting moiety, and transmembrane and signaling domains to determine which components augmented the ability of T cells to control HIV replication. This re-engineered CAR was at least 50-fold more potent in vitro at controlling HIV replication than the original CD4 CAR, or a TCR-based approach, and substantially better than broadly neutralizing antibody-based CARs. A humanized mouse model of HIV infection demonstrated that T cells expressing optimized CARs were superior at expanding in response to antigen, protecting CD4 T cells from infection, and reducing viral loads compared to T cells expressing the original, clinical trial CAR. Moreover, in a humanized mouse model of HIV treatment, CD4 CAR T cells containing the 4-1BB costimulatory domain controlled HIV spread after ART removal better than analogous CAR T cells containing the CD28 costimulatory domain. Together, these data indicate that potent HIV-specific T cells can be generated using improved CAR design and that CAR T cells could be important components of an HIV cure strategy.

Tool-ply friction in thermoplastic composite forming (CD-rom)

NARCIS (Netherlands)

ten Thije, R.H.W.; Akkerman, Remko; van der Meer, L.; Ubbink, M.P.; Boisse, P.

2008-01-01

Friction is an important phenomenon that can dominate the resulting product geometry of thermoplastic composites upon forming. A model was developed that predicts the friction between a thermoplastic laminate and a rigid tool. The mesoscopic model, based on the Reynolds’ equation for thin film

Mechanic waves in sand: Effect of polydispersity (CD-rom)

NARCIS (Netherlands)

Luding, Stefan; Mouraille, O.J.P.; Peukert, W.; Schreglmann, C.

2008-01-01

The sound propagation mechanisms inside dense granular matter are challenging the attempts to describe it because of the discrete nature of the material. Phenomena like dissipation, scattering, and dispersion are hard to predict based on the material state and/or properties and vice-versa. We

An electrically reprogrammable 1024 bits MNOS ROM using MNOS-SOS e/d technology

International Nuclear Information System (INIS)

Mackowiak, E.; Le Goascoz, V.

1976-01-01

A 1024 bits fully decoded electrically writable and erasable non volatile ROM is described. Memory cells and peripheral circuits are made using P channel silicon on sapphire enhancement depletion technology [fr

Isopleths of surface air concentration and surface air kerma rate due to a radioactive cloud released from a stack (3)

International Nuclear Information System (INIS)

Tachibana, Haruo; Kikuchi, Masamitsu; Sekita, Tsutomu; Yamaguchi, Takenori

2004-06-01

This report is a revised edition of 'Isopleths of Surface Air Concentration and Surface Air Absorbed Dose Rate due to a Radioactive Cloud Released from a Stack(II) '(JAERI-M 90-206) and based on the revised Nuclear Safety Guidelines reflected the ICRP1990 Recommendation. Characteristics of this report are the use of Air Karma Rate (Gy/h) instead of Air Absorbed Dose Rate (Gy/h), and the record of isopleths of surface air concentration and surface air karma rate on CD-ROM. These recorded data on CD-ROM can be printed out on paper and/or pasted on digital map by personal computer. (author)

Images of Kilauea East Rift Zone eruption, 1983-1993

Science.gov (United States)

Takahashi, Taeko Jane; Abston, C.C.; Heliker, C.C.

1995-01-01

This CD-ROM disc contains 475 scanned photographs from the U.S. Geological Survey Hawaii Observatory Library. The collection represents a comprehensive range of the best photographic images of volcanic phenomena for Kilauea's East Rift eruption, which continues as of September 1995. Captions of the images present information on location, geologic feature or process, and date. Short documentations of work by the USGS Hawaiian Volcano Observatory in geology, seismology, ground deformation, geophysics, and geochemistry are also included, along with selected references. The CD-ROM was produced in accordance with the ISO 9660 standard; however, it is intended for use only on DOS-based computer systems.

An optimized multilayer structure of CdS layer for CdTe solar cells application

International Nuclear Information System (INIS)

Han Junfeng; Liao Cheng; Jiang Tao; Spanheimer, C.; Haindl, G.; Fu, Ganhua; Krishnakumar, V.; Zhao Kui; Klein, A.; Jaegermann, W.

2011-01-01

Research highlights: → Two different methods to prepare CdS films for CdTe solar cells. → A new multilayer structure of window layer for the CdTe solar cell. → Thinner CdS window layer for the solar cell than the standard CdS layer. → Higher performance of solar cells based on the new multilayer structure. - Abstract: CdS layers grown by 'dry' (close space sublimation) and 'wet' (chemical bath deposition) methods are deposited and analyzed. CdS prepared with close space sublimation (CSS) has better crystal quality, electrical and optical properties than that prepared with chemical bath deposition (CBD). The performance of CdTe solar cell based on the CSS CdS layer has higher efficiency than that based on CBD CdS layer. However, the CSS CdS suffers from the pinholes. And consequently it is necessary to prepare a 150 nm thin film for CdTe/CdS solar cell. To improve the performance of CdS/CdTe solar cells, a thin multilayer structure of CdS layer (∼80 nm) is applied, which is composed of a bottom layer (CSS CdS) and a top layer (CBD CdS). That bi-layer film can allow more photons to pass through it and significantly improve the short circuit current of the CdS/CdTe solar cells.

SM-ROM-GL (Strong Motion Romania Ground Level Database

Directory of Open Access Journals (Sweden)

Ioan Sorin BORCIA

2015-07-01

Full Text Available The SM-ROM-GL database includes data obtained by the processing of records performed at ground level by the Romanian seismic networks, namely INCERC, NIEP, NCSRR and ISPH-GEOTEC, during recent seismic events with moment magnitude Mw ≥ 5 and epicenters located in Romania. All the available seismic records were re-processed using the same basic software and the same procedures and options (filtering and baseline correction, in order to obtain a consistent dataset. The database stores computed parameters of seismic motions, i.e. peak values: PGA, PGV, PGD, effective peak values: EPA, EPV, EPD, control periods, spectral values of absolute acceleration, relative velocity and relative displacement, as well as of instrumental intensity (as defined bz Sandi and Borcia in 2011. The fields in the database include: coding of seismic events, stations and records, a number of associated fields (seismic event source parameters, geographical coordinates of seismic stations, links to the corresponding ground motion records, charts of the response spectra of absolute acceleration, relative velocity, relative displacement and instrumental intensity, as well as some other representative parameters of seismic motions. The conception of the SM-ROM-GL database allows for an easy maintenance; such that elementary knowledge of Microsoft Access 2000 is sufficient for its operation.

The effects of neural mobilization on cervical radiculopathy patients' pain, disability, ROM, and deep flexor endurance.

Science.gov (United States)

Kim, Dong-Gyu; Chung, Sin Ho; Jung, Ho Bal

2017-09-22

Cervical radiculopathy (CR) is a disease of the cervical spine and a space-occupying lesion that occurs because of pathological problems with cervical nerve roots. Nerve root injury to produce functional disability. The purpose of this study was to examine the effects of neural mobilization with manual cervical traction (NMCT) compared with manual cervical traction (MCT) on pain, functional disability, muscle endurance, and range of motion (ROM) in individuals with CR patients. A blinded randomized clinical trial was conducted. Thirty CR patients were divided into two groups - those who received NMCT and those who received MCT. The intervention was applied three times per week for eight weeks. It was measured in order to determine the pain and functional disability in patients with CR. The numeric pain rating scale (NPRS), neck disability index (NDI), ROM, and deep flexor endurance of patients were measured prior to the experiment, four weeks, and eight weeks after the experiment to compare the time points. A repeated-measures analysis of variance was used to compare differences within each group prior to the experiment. And Bonferroni test was performed to examine the significance of each time point. There were significant differences within each group prior to the intervention, four weeks after the intervention, and eight weeks after the intervention in NPRS, NDI, ROM, and deep flexor endurance (Ppain relief, recovery from neck disability, ROM, and deep flexor endurance for patients with CR.

CdS-based p-i-n diodes using indium and copper doped CdS films by pulsed laser deposition

International Nuclear Information System (INIS)

Hernandez-Como, N; Berrellez-Reyes, F; Mizquez-Corona, R; Ramirez-Esquivel, O; Mejia, I; Quevedo-Lopez, M

2015-01-01

In this work we report a method to dope cadmium sulfide (CdS) thin films using pulsed laser deposition. Doping is achieved during film growth at substrate temperatures of 100 °C by sequential deposition of the CdS and the dopant material. Indium sulfide and copper disulfide targets were used as the dopant sources for n-type and p-type doping, respectively. Film resistivities as low as 0.2 and 1 Ω cm were achieved for indium and copper doped films, respectively. Hall effect measurements demonstrated the change in conductivity type from n-type to p-type when the copper dopants are incorporated into the film. The controlled incorporation of indium or copper, in the undoped CdS film, results in substitutional defects in the CdS, which increases the electron and hole concentration up to 4 × 10 18 cm −3 and 3 × 10 20 cm −3 , respectively. The results observed with CdS doping can be expanded to other chalcogenides material compounds by just selecting different targets. With the optimized doped films, CdS-based p-i-n diodes were fabricated yielding an ideality factor of 4, a saturation current density of 2 × 10 −6 A cm −2 and a rectification ratio of three orders of magnitude at ±3 V. (paper)

Clean focus, dose and CD metrology for CD uniformity improvement

Science.gov (United States)

Lee, Honggoo; Han, Sangjun; Hong, Minhyung; Kim, Seungyoung; Lee, Jieun; Lee, DongYoung; Oh, Eungryong; Choi, Ahlin; Kim, Nakyoon; Robinson, John C.; Mengel, Markus; Pablo, Rovira; Yoo, Sungchul; Getin, Raphael; Choi, Dongsub; Jeon, Sanghuck

2018-03-01

Lithography process control solutions require more exacting capabilities as the semiconductor industry goes forward to the 1x nm node DRAM device manufacturing. In order to continue scaling down the device feature sizes, critical dimension (CD) uniformity requires continuous improvement to meet the required CD error budget. In this study we investigate using optical measurement technology to improve over CD-SEM methods in focus, dose, and CD. One of the key challenges is measuring scanner focus of device patterns. There are focus measurement methods based on specially designed marks on scribe-line, however, one issue of this approach is that it will report focus of scribe line which is potentially different from that of the real device pattern. In addition, scribe-line marks require additional design and troubleshooting steps that add complexity. In this study, we investigated focus measurement directly on the device pattern. Dose control is typically based on using the linear correlation behavior between dose and CD. The noise of CD measurement, based on CD-SEM for example, will not only impact the accuracy, but also will make it difficult to monitor dose signature on product wafers. In this study we will report the direct dose metrology result using an optical metrology system which especially enhances the DUV spectral coverage to improve the signal to noise ratio. CD-SEM is often used to measure CD after the lithography step. This measurement approach has the advantage of easy recipe setup as well as the flexibility to measure critical feature dimensions, however, we observe that CD-SEM metrology has limitations. In this study, we demonstrate within-field CD uniformity improvement through the extraction of clean scanner slit and scan CD behavior by using optical metrology.

Purchasing an Encyclopedia: 12 Points To Consider. Fifth Edition.

Science.gov (United States)

American Library Association, Chicago, IL.

This book discusses issues to consider when purchasing an encyclopedia and provides reviews of eight print encyclopedias, six CD-ROM encyclopedias, and one online encyclopedia. Each review provides an address and discusses the history, scope and treatment, and quality and currency of the encyclopedia; for CD-ROM encyclopedias, the database…

Fusion energy 2002. 19th conference proceedings

International Nuclear Information System (INIS)

2003-01-01

This CD-ROM contains the proceedings of the 19th International Conference on Fusion energy 2002, held in Lyon, France, on 14-19 October 2002. The CD-Rom contains HTML files for navigation via WEB brouser, the papers in PDF and Acrobat Reader 5 for Windows, Mac-OS and UNIX

CdS loaded on coal based activated carbon nanofibers with enhanced photocatalytic property

Science.gov (United States)

Guo, Jixi; Guo, Mingxi; Jia, Dianzeng; Song, Xianli; Tong, Fenglian

2016-08-01

The coal based activated carbon nanofibers (CBACFs) were prepared by electrospinning a mixture of polyacrylonitrile (PAN) and acid treated coal. Cadmium sulfide (CdS) nanoparticles loaded on CBACFs were fabricated by solvothermal method. The obtained samples were characterized by FESEM, TEM, and XRD. The results reveal that the CdS nanoparticles are homogeneously dispersed on the surfaces of CBACFs. The CdS/CBACFs nanocomposites exhibited higher photoactivity for photodegradation of methyl blue (MB) under visible light irradiation than pure CdS nanoparticles. CBACFs can be used as low cost support materials for the preparation of nanocomposites with high photocatalytic activity.

Adolescencia, relaciones románticas y actividad sexual: una revisión

Directory of Open Access Journals (Sweden)

Elvia Vargas

2002-01-01

Full Text Available Se presenta una revisión de algunas de las investigaciones más recientes sobre la adolescencia y los factores asociados a las relaciones románticas y la actividad sexual durante la adolescencia. Se parte de la premisa de que el análisis de la iniciación romántica y sexual durante la adolescencia requiere de modelos de causalidad múltiple que permitan dar cuenta, conjuntamente, de los factores que se encuentran en los contextos individual, familiar y social asociados con estos dos procesos. Se destaca el papel de los padres en el desarrollo de hijos adolescentes autónomos, capaces de manejar la influencia negativa del grupo de pares. Se hacen algunas recomendaciones a los responsables de diseñar programas de prevención y a los interesados en el estudio de la adolescencia y en el desarrollo de la disciplina

First-principles-based analysis of the influence of Cu on CdTe electronic properties

International Nuclear Information System (INIS)

Krasikov, D.; Knizhnik, A.; Potapkin, B.; Selezneva, S.; Sommerer, T.

2013-01-01

The maximum voltage of CdTe solar cells is limited by low majority carrier concentration and doping difficulty. Copper that enters from the back contact can form both donors and acceptors in CdTe. It is empirically known that the free carrier concentration is several orders lower than the total Cu concentration. Simplified thermodynamic models of defect compensation after Cu introduction can be found in literature. We present a first-principles-based analysis of kinetics of defect formation upon Cu introduction, and show that Cu i is mobile at room temperature. Calculations of properties of Cu i –V Cd and Cu i –Cu Cd complexes show that the neutral Cu i –Cu Cd complex is mobile at elevated temperatures, while formation of the V Cd –Cu i complex is unlikely because it transforms into the Cu Cd defect. - Highlights: ► First-principles calculations of copper defects in CdTe are performed. ► Formation of Cd vacancy + Cu interstitial(Cu i ) complex is unlikely. ► Cu i defect is mobile at room temperature. ► Cu i + Cu on Cd-site (Cu Cd ) complex is mobile at elevated temperature. ► Cu Cd defect forms by kicking-out of the regular lattice Cd by Cu i

A reduced order aerothermodynamic modeling framework for hypersonic vehicles based on surrogate and POD

Directory of Open Access Journals (Sweden)

Chen Xin

2015-10-01

Full Text Available Aerothermoelasticity is one of the key technologies for hypersonic vehicles. Accurate and efficient computation of the aerothermodynamics is one of the primary challenges for hypersonic aerothermoelastic analysis. Aimed at solving the shortcomings of engineering calculation, computation fluid dynamics (CFD and experimental investigation, a reduced order modeling (ROM framework for aerothermodynamics based on CFD predictions using an enhanced algorithm of fast maximin Latin hypercube design is developed. Both proper orthogonal decomposition (POD and surrogate are considered and compared to construct ROMs. Two surrogate approaches named Kriging and optimized radial basis function (ORBF are utilized to construct ROMs. Furthermore, an enhanced algorithm of fast maximin Latin hypercube design is proposed, which proves to be helpful to improve the precisions of ROMs. Test results for the three-dimensional aerothermodynamic over a hypersonic surface indicate that: the ROMs precision based on Kriging is better than that by ORBF, ROMs based on Kriging are marginally more accurate than ROMs based on POD-Kriging. In a word, the ROM framework for hypersonic aerothermodynamics has good precision and efficiency.

The Distribution of Information: The Role for Online Public Access Catalogs.

Science.gov (United States)

Matthews, Joseph R.

1994-01-01

Describes the Online Public Access Catalog (OPAC) and the inclusion of abstracting and indexing industry databases in OPACs. Topics addressed include the implications of including abstracting and indexing tape and CD-ROM products in OPACs; the need for standards allowing library systems to communicate with dissimilar CD-ROM products; and computer,…

Looking Up: Multimedia about Space and Flight.

Science.gov (United States)

Walter, Virginia A.

1998-01-01

The best CD-ROMs for young people about space and flight exploit the promise of hypermedia to create informative simulations. This article provides an annotated bibliography of CD-ROMs on astronomy and flight for K-12 students; suggests book and Internet connections; and highlights poetry for astronomers, science fiction, a biography of Charles…

T cell receptor zeta allows stable expression of receptors containing the CD3gamma leucine-based receptor-sorting motif

DEFF Research Database (Denmark)

Dietrich, J; Geisler, C

1998-01-01

The leucine-based motif in the T cell receptor (TCR) subunit CD3gamma constitutes a strong internalization signal. In fully assembled TCR this motif is inactive unless phosphorylated. In contrast, the motif is constitutively active in CD4/CD3gamma and Tac/CD3gamma chimeras independently of phosph......The leucine-based motif in the T cell receptor (TCR) subunit CD3gamma constitutes a strong internalization signal. In fully assembled TCR this motif is inactive unless phosphorylated. In contrast, the motif is constitutively active in CD4/CD3gamma and Tac/CD3gamma chimeras independently...... of phosphorylation and leads to rapid internalization and sorting of these chimeras to lysosomal degradation. Because the TCRzeta chain rescues incomplete TCR complexes from lysosomal degradation and allows stable surface expression of fully assembled TCR, we addressed the question whether TCRzeta has the potential...... to mask the CD3gamma leucine-based motif. By studying CD4/CD3gamma and CD16/CD3gamma chimeras, we found that CD16/CD3gamma chimeras associated with TCRzeta. The CD16/CD3gamma-TCRzeta complexes were stably expressed at the cell surface and had a low spontaneous internalization rate, indicating...

White light emitting device based on single-phase CdS quantum dots

Science.gov (United States)

Li, Feng; Nie, Chao; You, Lai; Jin, Xiao; Zhang, Qin; Qin, Yuancheng; Zhao, Feng; Song, Yinglin; Chen, Zhongping; Li, Qinghua

2018-05-01

White light emitting diodes (WLEDs) based on quantum dots (QDs) are emerging as robust candidates for white light sources, however they are suffering from the problem of energy loss resulting from the re-absorption and self-absorption among the employed QDs of different peak wavelengths. It still remains a challenging task to construct WLEDs based on single-phase QD emitters. Here, CdS QDs with short synthesis times are introduced to the fabrication of WLEDs. With a short synthesis time, on one hand, CdS QDs with a small diameter with blue emission can be obtained. On the other hand, surface reconstruction barely has time to occur, and the surface is likely defect-ridden, which enables the existence of a broad emission covering the range of green, yellow and red regions. This is essential for the white light emission of CdS QDs, and is very important for WLED applications. The temporal evolution of the PL spectra for CdS QDs was obtained to investigate the influence of growth time on the luminescent properties. The CdS QDs with a growth time of 0.5 min exhibited a colour rendering index (CRI) of 79.5 and a correlated colour temperature (CCT) of 6238 K. With increasing reaction time, the colour coordinates of the CdS QDs will move away from the white light region in the CIE 1931 chromaticity diagram. By integrating the as prepared white light emission CdS QDs with a violet GaN chip, WLEDs were fabricated. The fabricated WLEDs exhibited a CRI of 87.9 and a CCT of 4619 K, which satisfy the demand of general illumination. The luminous flux and the luminous efficiency of the fabricated WLEDs, being less advanced than current commercial white light sources, can be further improved, meaning there is a need for much more in-depth studies on white light emission CdS QDs.

Pitfalls in the Assessment, Analysis, and Interpretation of Routine Outcome Monitoring (ROM) Data : Results from an Outpatient Clinic for Integrative Mental Health

NARCIS (Netherlands)

Hoenders, Rogier H. J.; Bos, Elisabeth H.; Bartels-Velthuis, Agna A.; Vollbehr, Nina K.; van der Ploeg, Karen; de Jonge, Peter; de Jong, Joop T. V. M.

There is considerable debate about routine outcome monitoring (ROM) for scientific or benchmarking purposes. We discuss pitfalls associated with the assessment, analysis, and interpretation of ROM data, using data of 376 patients. 206 patients (55 %) completed one or more follow-up measurements.

Provocarea Facebook pentru bibliotecile publice din România

Directory of Open Access Journals (Sweden)

Octavia-Luciana Madge

2014-01-01

Full Text Available Reţelele sociale şi-au câştigat rapid un loc în viaţa noastră şi în activitatea multor organizaţii şi instituţii publice şi private. La nivelul bibliotecilor, reţelele sociale şi-au demonstrat utilitatea şi rolul în calitate de instrumente de marketing pentru o mai bună comunicare cu utilizatorii. Bibliotecile publice din România au cunoscut în ultimul timp transformări mari în ceea ce priveşte modul de abordare a relaţiei cu utilizatorii şi îmbunătăţirea activităţii lor. Au lansat, de asemenea, o serie de noi servicii pentru a răspunde nevoilor comunităţii pe care o servesc şi pentru a atrage noi utilizatori. Implementarea şi utilizarea de noi aplicaţii precum reţelele de socializare online, mai exact Facebook, a fost una dintre aceste dezvoltări recente. Această lucrare analizează modul în care reţelele sociale sunt utilizate la nivelul bibliotecilor publice din România prin exemplul a trei biblioteci publice mari şi a modului în care aceste biblioteci îşi promovează serviciile prin intermediul reţelei Facebook.

Phase diagram of SnTe-CdSe cross-section of SnTe+CdSe reversible SnSe+CdTe ternary reciprocal system

International Nuclear Information System (INIS)

Dubrovin, I.V.; Budennaya, L.D.; Mizetskaya, I.B.; Sharkina, Eh.V.

1986-01-01

Phase equilibrium diagram of SnTe-CdSe cross-section of Sn, Cd long Te, Se ternary reciprocal system is investigated using the methods of differential thermal, X-ray phase, and microstructural analyses. Maximum length of solid solutions on the base of SnTe corresponds to approximately 14 mol.% at 1050 K and approximately 3 mol.% of CdSe at 670 K. Region of solid solutions on the base of CdSe corresponds to less than 1 mol.% of SnTe at room temperature. SnTe-CdSe cross-section is not a quasibinar one. Equilibrium is shifted to the left in the SnTe+CdSe reversible SnSe+CdTe reciprocal system

Executive Summaries: CIL '90.

Science.gov (United States)

Elsweiler, John A., Jr.; And Others

1990-01-01

Presents summaries of 12 papers presented at the 1990 Computers in Libraries Conference. Topics discussed include online searching; microcomputer-based serials management; microcomputer-based workstations; online public access catalogs (OPACs); multitype library networking; CD-ROM searches; locally mounted online databases; collection evaluation;…

Computer aided systems human engineering: A hypermedia tool

Science.gov (United States)

Boff, Kenneth R.; Monk, Donald L.; Cody, William J.

1992-01-01

The Computer Aided Systems Human Engineering (CASHE) system, Version 1.0, is a multimedia ergonomics database on CD-ROM for the Apple Macintosh II computer, being developed for use by human system designers, educators, and researchers. It will initially be available on CD-ROM and will allow users to access ergonomics data and models stored electronically as text, graphics, and audio. The CASHE CD-ROM, Version 1.0 will contain the Boff and Lincoln (1988) Engineering Data Compendium, MIL-STD-1472D and a unique, interactive simulation capability, the Perception and Performance Prototyper. Its features also include a specialized data retrieval, scaling, and analysis capability and the state of the art in information retrieval, browsing, and navigation.

CdCl2 passivation of polycrystalline CdMgTe and CdZnTe absorbers for tandem photovoltaic cells

Science.gov (United States)

Swanson, Drew E.; Reich, Carey; Abbas, Ali; Shimpi, Tushar; Liu, Hanxiao; Ponce, Fernando A.; Walls, John M.; Zhang, Yong-Hang; Metzger, Wyatt K.; Sampath, W. S.; Holman, Zachary C.

2018-05-01

As single-junction silicon solar cells approach their theoretical limits, tandems provide the primary path to higher efficiencies. CdTe alloys can be tuned with magnesium (CdMgTe) or zinc (CdZnTe) for ideal tandem pairing with silicon. A II-VI/Si tandem holds the greatest promise for inexpensive, high-efficiency top cells that can be quickly deployed in the market using existing polycrystalline CdTe manufacturing lines combined with mature silicon production lines. Currently, all high efficiency polycrystalline CdTe cells require a chloride-based passivation process to passivate grain boundaries and bulk defects. This research examines the rich chemistry and physics that has historically limited performance when extending Cl treatments to polycrystalline 1.7-eV CdMgTe and CdZnTe absorbers. A combination of transmittance, quantum efficiency, photoluminescence, transmission electron microscopy, and energy-dispersive X-ray spectroscopy clearly reveals that during passivation, Mg segregates and out-diffuses, initially at the grain boundaries but eventually throughout the bulk. CdZnTe exhibits similar Zn segregation behavior; however, the onset and progression is localized to the back of the device. After passivation, CdMgTe and CdZnTe can render a layer that is reduced to predominantly CdTe electro-optical behavior. Contact instabilities caused by inter-diffusion between the layers create additional complications. The results outline critical issues and paths for these materials to be successfully implemented in Si-based tandems and other applications.

Data base for early postfire succession in Northern Rocky Mountain forests

Science.gov (United States)

Peter F. Stickney; Robert B. Campbell

2000-01-01

Web site and CD-ROM include 21 pages of text plus electronic data for 55 succession sites including color plates, tables, and figures. Provides data on quantitative postfire changes of plant species and forest vegetation components for up to the first 25 years of secondary plant succession for 55 forest sites in northern Idaho and northwestern Montana. Cover (aerial...

MoKS teistes koostööprojektides / John Grzinich

Index Scriptorium Estoniae

Grzinich, John

2005-01-01

13. III Genfis toimunud helikunstiüritusest "VernalFLUX / Kevadvool", millest Eestist võtsid osa MoKS'i koordinaatorid John Grzinich ja Evelyn Müürsepp, nende performance'ist "Maaheli. Unustatud unistused". Uuest organisatsioonist Claudmirror, mis on välja andnud seitse CD-ROM-i, nende seas John Grzinichi CD-ROM-i "Võrdsed ja kauged jooned"

75 FR 9380 - Cooperative Conservation Partners Initiative; Wetlands Reserve Enhancement Program

Science.gov (United States)

2010-03-02

... paper) of the written proposal and one electronic copy on CD-ROM in MS WORD or PDF. If submitting more... proposal and one electronic copy on CD-ROM in MS WORD or PDF. If submitting more than one project proposal... Mexico. Stretching 2,350 miles from its headwaters at Lake Itasca, Minnesota, to the mouth of the Gulf of...

Artificial Intelligence-Explosive Ordnance Disposal Information Search, Retrieval, and Delivery System

Science.gov (United States)

1992-04-01

megabytes greater than required to store the operating system and X-Windows. * CD-ROM Player. Standard CD-ROM player using ISO 9660 file format...CAVGERRO 235 .4596 . 8583 .0000 4.0000 42 CAVGFOUN 235 3.9362 .3700 .0000 4.0000 43 SlIT 235 172.3106 207.4205 .0000 1039.0000 44 S2T 235 122.0638

Support-Vector-Machine-Based Reduced-Order Model for Limit Cycle Oscillation Prediction of Nonlinear Aeroelastic System

Directory of Open Access Journals (Sweden)

Gang Chen

2012-01-01

Full Text Available It is not easy for the system identification-based reduced-order model (ROM and even eigenmode based reduced-order model to predict the limit cycle oscillation generated by the nonlinear unsteady aerodynamics. Most of these traditional ROMs are sensitive to the flow parameter variation. In order to deal with this problem, a support vector machine- (SVM- based ROM was investigated and the general construction framework was proposed. The two-DOF aeroelastic system for the NACA 64A010 airfoil in transonic flow was then demonstrated for the new SVM-based ROM. The simulation results show that the new ROM can capture the LCO behavior of the nonlinear aeroelastic system with good accuracy and high efficiency. The robustness and computational efficiency of the SVM-based ROM would provide a promising tool for real-time flight simulation including nonlinear aeroelastic effects.

Şcoli şi biserici româneşti din Peninsula Balcanică 1864-1948. Documente de arhivă

Directory of Open Access Journals (Sweden)

Adina Berciu-Drăghicescu

2006-01-01

Full Text Available Articolul de faţă privind şcolile şi bisericile româneşti din Peninsula Balcanică în perioada 1918-1948 este realizat pe baza unor documente identificate în fonduri păstrate la Arhivele Diplomatice ale Ministerului Afacerilor Externe şi la Direcţia Arhivelor Naţioanle Istorice Centrale din Bucureşti. Au fost studiate şi selectate documente de cea mai mare semnificaţie în scopul prezentării evoluţiei situaţiei şcolilor şi bisericilor comunităţilor româneşti situate la sud de Dunăre începând cu anul 1864, când a fost înfiinţată prima şcoală în Târnova (Macedonia şi până în 1948 când statul român a abandonat acţiunea iniţiată de conducătorul Al. Ioan Cuza. Articolul prezintă această situaţie, foarte dramatică, a comunităţilor româneşti din Balcani pe baza documentelor de arhivă.

Chip-based magnetic solid phase microextraction coupled with ICP-MS for the determination of Cd and Se in HepG2 cells incubated with CdSe quantum dots.

Science.gov (United States)

Yu, Xiaoxiao; Chen, Beibei; He, Man; Wang, Han; Hu, Bin

2018-03-01

The quantification of trace Cd and Se in cells incubated with CdSe quantum dots (QDs) is critical to investigate the cytotoxicity of CdSe QDs. In this work, a miniaturized platform, namely chip-based magnetic solid phase microextraction (MSPME) packing with sulfhydryl group functionalized magnetic nanoparticles, was fabricated and combined with inductively coupled plasma mass spectrometry (ICP-MS) for the determination of trace Cd and Se in cells. Under the optimized conditions, the limits of detection (LOD) of the developed chip-based MSPME-ICP-MS system are 2.2 and 21ngL -1 for Cd and Se, respectively. The proposed method is applied successfully to the analysis of total and released small molecular fraction of Cd and Se in Human hepatocellular carcinoma cells (HepG2 cells) incubated with CdSe QDs, and the recoveries for the spiked samples are in the range of 86.0-109%. This method shows great promise to analyze cell samples and the obtained results are instructive to explore the cytotoxicity mechanism of CdSe QDs in cells. Copyright © 2017 Elsevier B.V. All rights reserved.

Biomes and Natural Cycles. [CD-ROM].

Science.gov (United States)

1996

This interactive multimedia software illustrates and explains life on planet Earth through colorful and dynamic representations. Clear explanations and animation elucidate a variety of subjects such as the organization of the ecosphere, the flux of energy, water cycles, climates, and characteristics of regions across the globe. Five animated films…

Chinese Language Video Clips. [CD-ROM].

Science.gov (United States)

Fleming, Stephen; Hipley, David; Ning, Cynthia

This compact disc includes video clips covering six topics for the learner of Chinese: personal information, commercial transactions, travel and leisure, health and sports, food and school. Filmed on location in Beijing, these naturalistic video clips consist mainly of unrehearsed interviews of ordinary people. The learner is lead through a series…

Lineage determination of CD7+ CD5- CD2- and CD7+ CD5+ CD2- lymphoblasts: studies on phenotype, genotype, and gene expression of myeloperoxidase, CD3 epsilon, and CD3 delta.

Science.gov (United States)

Yoneda, N; Tatsumi, E; Teshigawara, K; Nagata, S; Nagano, T; Kishimoto, Y; Kimura, T; Yasunaga, K; Yamaguchi, N

1994-04-01

The gene expression of myeloperoxidase (MPO), CD3 epsilon, and CD3 delta molecules, the gene rearrangement of T-cell receptor (TCR) delta, gamma, and beta and immunoglobulin heavy (IgH) chain, and the expression of cell-surface antigens were investigated in seven cases of CD7+ CD5- CD2- and four cases of CD7+ CD5+ CD2- acute lymphoblastic leukemia or lymphoblastic lymphoma (ALL/LBL) blasts, which were negative for cytochemical myeloperoxidase (cyMPO). More mature T-lineage blasts were also investigated in a comparative manner. In conclusion, the CD7+ CD5- CD2- blasts included four categories: undifferentiated blasts without lineage commitment, T-lineage blasts, T-/myeloid lineage blasts, and cyMPO-negative myeloblasts. The CD7+ CD5+ CD2- blasts included two categories; T-lineage and T-/myeloid lineage blasts. The 11 cases were of the germ-line gene (G) for TCR beta and IgH. Four cases were G for TCR delta and TCR gamma. The others were of the monoclonally rearranged gene (R) for TCR delta and G for TCR gamma or R for both TCR delta and TCR gamma. The expression or in vitro induction of CD13 and/or CD33 antigens correlated with the immaturity of these neoplastic T cells, since it was observed in all 11 CD7+ CD5- CD2- and CD7+ CD5+ CD2-, and some CD7+ CD5+ CD2+ (CD3- CD4- CD8-) cases, but not in CD3 +/- CD4+ CD8+ or CD3+ CD4+ CD8- cases. CD3 epsilon mRNA, but not CD3 delta mRNA, was detected in two CD7+ CD5- CD2- cases, while mRNA of neither of the two CD3 molecules was detected in the other tested CD7+ CD5- CD2- cases. In contrast, mRNA of both CD3 epsilon and CD3 delta were detected in all CD7+ CD5+ CD2- cases, indicating that CD7+ CD5- CD2- blasts at least belong to T-lineage. The blasts of two CD7+ CD5- CD2- cases with entire germ-line genes and without mRNA of the three molecules (MPO, CD3 epsilon, and CD3 delta) were regarded as being at an undifferentiated stage prior to their commitment to either T- or myeloid-lineage. The co-expression of the genes of MPO

Polymeric membrane sensors based on Cd(II) Schiff base complexes for selective iodide determination in environmental and medicinal samples.

Science.gov (United States)

Singh, Ashok Kumar; Mehtab, Sameena

2008-01-15

The two cadmium chelates of schiff bases, N,N'-bis(salicylidene)-1,4-diaminobutane, (Cd-S(1)) and N,N'-bis(salicylidene)-3,4-diaminotoluene (Cd-S(2)), have been synthesized and explored as ionophores for preparing PVC-based membrane sensors selective to iodide(I) ion. Potentiometric investigations indicate high affinity of these receptors for iodide ion. Polyvinyl chloride (PVC)-based membranes of Cd-S(1) and Cd-S(2) using as hexadecyltrimethylammonium bromide (HTAB) cation discriminator and o-nitrophenyloctyl ether (o-NPOE), dibutylphthalate (DBP), acetophenone (AP) and tributylphosphate (TBP) as plasticizing solvent mediators were prepared and investigated as iodide-selective sensors. The best performance was shown by the membrane of composition (w/w) of (Cd-S(1)) (7%):PVC (31%):DBP (60%):HTAB (2%). The sensor works well over a wide concentration range 5.3x10(-7) to 1.0x10(-2)M with Nernstian compliance (59.2mVdecade(-1) of activity) within pH range 2.5-9.0 with a response time of 11s and showed good selectivity for iodide ion over a number of anions. The sensor exhibits adequate life (3 months) with good reproducibility (S.D.+/-0.24mV) and could be used successfully for the determination of iodide content in environmental water samples and mouth wash samples.

Introducing students to ocean modeling via a web-based implementation for the Regional Ocean Modeling System (ROMS) river plume case study

Science.gov (United States)

Harris, C. K.; Overeem, I.; Hutton, E.; Moriarty, J.; Wiberg, P.

2016-12-01

Numerical models are increasingly used for both research and applied sciences, and it is important that we train students to run models and analyze model data. This is especially true within oceanographic sciences, many of which use hydrodynamic models to address oceanographic transport problems. These models, however, often require a fair amount of training and computer skills before a student can run the models and analyze the large data sets produced by the models. One example is the Regional Ocean Modeling System (ROMS), an open source, three-dimensional primitive equation hydrodynamic ocean model that uses a structured curvilinear horizontal grid. It currently has thousands of users worldwide, and the full model includes modules for sediment transport and biogeochemistry, and several options for turbulence closures and numerical schemes. Implementing ROMS can be challenging to students, however, in part because the code was designed to provide flexibility for the choice of model parameterizations and processes, and to run on a variety of High Performance Computing (HPC) platforms. To provide a more accessible tool for classroom use, we have modified an existing idealized ROMS implementation to be run on a High Performance Computer (HPC) via the WMT (Web Modeling Toolkit), and developed a series of lesson plans that explore sediment transport within the idealized model domain. This has addressed our goal to provide a relatively easy introduction to the numerical modeling process that can be used within upper level undergraduate and graduate classes to explore sediment transport on continental shelves. The model implementation includes wave forcing, along-shelf currents, a riverine source, and suspended sediment transport. The model calculates suspended transport and deposition of sediment delivered to the continental shelf by a riverine flood. Lesson plans lead the students through running the model on a remote HPC, modifying the standard model. The lesson

64nm pitch metal1 double patterning metrology: CD and OVL control by SEMCD, image based overlay and diffraction based overlay

Science.gov (United States)

Ducoté, Julien; Dettoni, Florent; Bouyssou, Régis; Le-Gratiet, Bertrand; Carau, Damien; Dezauzier, Christophe

2015-03-01

Patterning process control of advanced nodes has required major changes over the last few years. Process control needs of critical patterning levels since 28nm technology node is extremely aggressive showing that metrology accuracy/sensitivity must be finely tuned. The introduction of pitch splitting (Litho-Etch-Litho-Etch) at 14FDSOInm node requires the development of specific metrologies to adopt advanced process control (for CD, overlay and focus corrections). The pitch splitting process leads to final line CD uniformities that are a combination of the CD uniformities of the two exposures, while the space CD uniformities are depending on both CD and OVL variability. In this paper, investigations of CD and OVL process control of 64nm minimum pitch at Metal1 level of 14FDSOI technology, within the double patterning process flow (Litho, hard mask etch, line etch) are presented. Various measurements with SEMCD tools (Hitachi), and overlay tools (KT for Image Based Overlay - IBO, and ASML for Diffraction Based Overlay - DBO) are compared. Metrology targets are embedded within a block instanced several times within the field to perform intra-field process variations characterizations. Specific SEMCD targets were designed for independent measurement of both line CD (A and B) and space CD (A to B and B to A) for each exposure within a single measurement during the DP flow. Based on those measurements correlation between overlay determined with SEMCD and with standard overlay tools can be evaluated. Such correlation at different steps through the DP flow is investigated regarding the metrology type. Process correction models are evaluated with respect to the measurement type and the intra-field sampling.

Study and development of new CdTe and CdZnTe detection structures for X and {gamma} imagery; Etude et realisation de nouvelles structures de detection a base de CdTe et CdZnTe pour l`imagerie X et {gamma}

Energy Technology Data Exchange (ETDEWEB)

Rosaz, M

1997-10-24

The aim of this study is to show the interest of applying cadmium telluride (CdTe) for X- and {gamma}- ray imaging applications, with specific technological (via contact nature) and geometric (via Frisch grids) structures suited for each application. This work is divided into three different but complementary parts: the first part describes a simulation model which allows a better understanding of CdTe based {gamma}- ray detectors. The new feature of this model compared to previous ones, is that it is able to take into account the electric field`s non uniform spatial distribution inside the detector s. The results enable us to de-convolute the influence of material and contact parameters on the spectrometric performances (energy resolution and peak/valley ratio) of CdTe based detectors; the second part presents different technological structures deposited upon CdTe, (grown by two different methods, i.e Bridgman and High Pressure Bridgman). These structures were characterised in X- and {gamma}- ray detection; theoretical models are developed which allow a certain insight into the detection properties of each couple (material + contact); the third part deals with new contact geometries which allow a screening effect of the bulk (analogous to the Frisch grid effect in gaseous detectors) resulting in improved energy resolution and peak/valley ratios; encouraging first results on prototypes are presented and discussed. This work has allowed a better understanding of physical behaviour of CdTe based detectors, coupled with advances in technological issues to upgrade the overall performances of these detectors for application in X- and {gamma}- ray imaging. (author) 93 refs.

Tumor-Targeted Human T Cells Expressing CD28-Based Chimeric Antigen Receptors Circumvent CTLA-4 Inhibition.

Directory of Open Access Journals (Sweden)

Maud Condomines

Full Text Available Adoptive T cell therapy represents a promising treatment for cancer. Human T cells engineered to express a chimeric antigen receptor (CAR recognize and kill tumor cells in a MHC-unrestricted manner and persist in vivo when the CAR includes a CD28 costimulatory domain. However, the intensity of the CAR-mediated CD28 activation signal and its regulation by the CTLA-4 checkpoint are unknown. We investigated whether T cells expressing an anti-CD19, CD3 zeta and CD28-based CAR (19-28z displayed the same proliferation and anti-tumor abilities than T cells expressing a CD3 zeta-based CAR (19z1 costimulated through the CD80/CD28, ligand/receptor pathway. Repeated in vitro antigen-specific stimulations indicated that 19-28z+ T cells secreted higher levels of Th1 cytokines and showed enhanced proliferation compared to those of 19z1+ or 19z1-CD80+ T cells. In an aggressive pre-B cell leukemia model, mice treated with 19-28z+ T cells had 10-fold reduced tumor progression compared to those treated with 19z1+ or 19z1-CD80+ T cells. shRNA-mediated CTLA-4 down-regulation in 19z1-CD80+ T cells significantly increased their in vivo expansion and anti-tumor properties, but had no effect in 19-28z+ T cells. Our results establish that CTLA-4 down-regulation may benefit human adoptive T cell therapy and demonstrate that CAR design can elude negative checkpoints to better sustain T cell function.

Anti-proliferative effects of T cells expressing a ligand-based chimeric antigen receptor against CD116 on CD34+ cells of juvenile myelomonocytic leukemia

Directory of Open Access Journals (Sweden)

Yozo Nakazawa

2016-03-01

Full Text Available Abstract Background Juvenile myelomonocytic leukemia (JMML is a fatal, myelodysplastic/myeloproliferative neoplasm of early childhood. Patients with JMML have mutually exclusive genetic abnormalities in granulocyte-macrophage colony-stimulating factor (GM-CSF receptor (GMR, CD116 signaling pathway. Allogeneic hematopoietic stem cell transplantation is currently the only curative treatment option for JMML; however, disease recurrence is a major cause of treatment failure. We investigated adoptive immunotherapy using GMR-targeted chimeric antigen receptor (CAR for JMML. Methods We constructed a novel CAR capable of binding to GMR via its ligand, GM-CSF, and generated piggyBac transposon-based GMR CAR-modified T cells from three healthy donors and two patients with JMML. We further evaluated the anti-proliferative potential of GMR CAR T cells on leukemic CD34+ cells from six patients with JMML (two NRAS mutations, three PTPN11 mutations, and one monosomy 7, and normal CD34+ cells. Results GMR CAR T cells from healthy donors suppressed the cytokine-dependent growth of MO7e cells, but not the growth of K562 and Daudi cells. Co-culture of healthy GMR CAR T cells with CD34+ cells of five patients with JMML at effector to target ratios of 1:1 and 1:4 for 2 days significantly decreased total colony growth, regardless of genetic abnormality. Furthermore, GMR CAR T cells from a non-transplanted patient and a transplanted patient inhibited the proliferation of respective JMML CD34+ cells at onset to a degree comparable to healthy GMR CAR T cells. Seven-day co-culture of GMR CAR T cells resulted in a marked suppression of JMML CD34+ cell proliferation, particularly CD34+CD38− cell proliferation stimulated with stem cell factor and thrombopoietin on AGM-S3 cells. Meanwhile, GMR CAR T cells exerted no effects on normal CD34+ cell colony growth. Conclusions Ligand-based GMR CAR T cells may have anti-proliferative effects on stem and progenitor cells in JMML.

Galvenais varonis Dž.K.Roulingas romānu sērijā "Harijs Poters"

OpenAIRE

Kalsone, Ineta

2012-01-01

Dotā bakalaura darba temats ir "Galvenais varonis Dž.K. Roulingas romānu sērijā "Harijs Poters". Pirmajā nodaļā es analizēju sērijas popularitāti, publicēšanas datus un apbalvojumus, ko saņēmusi Dž.K. Roulinga. Otrajā nodaļā tiek analizēti dažādi raksturojuma veidi. Sīkāk tiek pētīta galvenā varoņa un citu nozīmīgāko tēlu loma. Meklējuma literatūras elementi,kas dod pamatu galvenā varoņa izaugsmei, tika analizēti detalizēti. Trešajā nodaļā tiek analizēta galvenā varoņa izaugsme šajā romānu sē...

Electrodeposition of CdTe thin film from acetate-based ionic liquid bath

Science.gov (United States)

Waldiya, Manmohansingh; Bhagat, Dharini; Mukhopadhyay, Indrajit

2018-05-01

CdTe being a direct band gap semiconductor, is mostly used in photovoltaics. Here we present, the synthesis of CdTe thin film on fluorine doped tin oxide (FTO) substrate potentiostatically using 1-butyl-3-methylimidazolium acetate ([Bmim][Ac]) ionic liquid (IL) bath at 90 °C. Major advantages of using electrodeposition involves process simplicity, large scalability & economic viability. Some of the benefits offered by IL electrolytic bath are low vapour pressure, wide electrochemical window, and good ionic mobility. Cd(CH3COO)2 (anhydrous) and TeO2 were used as the source precursors. The IL electrolytic bath temperature was kept at 90 °C for deposition, owing to the limited solubility of TeO2 in [Bmim][Ac] IL at room temperature. Cathodic electrodeposition was carried out using a three electrode cell setup at a constant potential of -1.20 V vs. platinum (Pt) wire. The CdTe/FTO thin film were annealed in argon (Ar) atmosphere. Optical study of nanostructured CdTe film were done using UV-Vis-IR and Raman spectroscopy. Raman analysis confirms the formation of CdTe having surface optics (SO) mode at 160.6 cm-1 and transverse optics (TO) mode at 140.5 cm-1. Elemental Te peaks at 123, 140.5 and 268 cm-1 were also observed. The optical band gap of Ar annealed CdTe thin film were found to be 1.47 eV (absorbance band edge ˜ 846 nm). The optimization of deposition parameters using acetate-based IL electrolytic bath to get nearly stoichiometric CdTe thin film is currently being explored.

Nuclear data retrieval for PC applications, PCNuDat

International Nuclear Information System (INIS)

Kinsey, R.R.

1996-01-01

The PCNuDat program for IBM-PC compatibles is similar to the NuDat program available through the NNDC Online Nuclear Data Service. They provide a user with access to nuclear data in a convenient and menu driven system. This data is useful in both basic and applied research. The nuclear base used by NuDat is extracted from several data bases maintained at the National Nuclear Data Center (NNDC). The program is an extended DOS program which uses 32 bit addressing. It can run in a DOS window on all the current Windows operating systems. The program and its data base are currently available on both a CD-ROM or electronically over the Internet. Electronic access can be made through the NNDC's Web home page. The files may also be FTP'd from the public area under the [pc prog] directory on bnlnd2.dne.bnl.gov. The CD-ROM version also contains the Nuclear Science References (NSR) data base and its retrieval program, Papyrus NSR

BOREAS Level-3a Landsat TM Imagery: Scaled At-sensor Radiance in BSQ Format

Science.gov (United States)

Nickerson, Jaime; Hall, Forrest G. (Editor); Knapp, David; Newcomer, Jeffrey A.; Cihlar, Josef

2000-01-01

For BOREAS, the level-3a Landsat TM data, along with the other remotely sensed images, were collected in order to provide spatially extensive information over the primary study areas. This information includes radiant energy, detailed land cover, and biophysical parameter maps such as FPAR and LAI. Although very similar in content to the level-3s Landsat TM products, the level-3a images were created to provide users with a more usable BSQ format and to provide information that permitted direct determination of per-pixel latitude and longitude coordinates. Geographically, the level-3a images cover the BOREAS NSA and SSA. Temporally, the images cover the period of 22-Jun-1984 to 30-Jul-1996. The images are available in binary, image-format files. With permission from CCRS and RSI, several of the full-resolution images are included on the BOREAS CD-ROM series. Due to copyright issues, the images not included on the CD-ROM may not be publicly available. See Sections 15 and 16 for information about how to acquire the data. Information about the images not on the CD-ROMs is provided in an inventory listing on the CD-ROMs.

COPPER RESISTANT STRAIN CANDIDA TROPICALIS RomCu5 INTERACTION WITH SOLUBLE AND INSOLUBLE COPPER COMPOUNDS

Directory of Open Access Journals (Sweden)

Ie. P. Prekrasna

2015-10-01

Full Text Available The focus of the study was interaction of Candida tropicalis RomCu5 isolated from highland Ecuador ecosystem with soluble and insoluble copper compounds. Strain C. tropicalis RomCu5 was cultured in a liquid medium of Hiss in the presence of soluble (copper citrate and CuCl2 and insoluble (CuO and CuCO3 copper compounds. The biomass growth was determined by change in optical density of culture liquid, composition of the gas phase was measured on gas chromatograph, redox potential and pH of the culture fluid was defined potentiometrically. The concentration of soluble copper compounds was determined colorimetrically. Maximal permissible concentration of Cu2+ for C. tropicalis RomCu5 was 30 000 ppm of Cu2+ in form of copper citrate and 500 ppm of Cu2+ in form of CuCl2. C. tropicalis was metabolically active at super high concentrations of Cu2+, despite the inhibitory effect of Cu2+. C. tropicalis immobilized Cu2+ in the form of copper citrate and CuCl2 by it accumulation in the biomass. Due to medium acidification C. tropicalis dissolved CuO and CuCO3. High resistance of C. tropicalis to Cu2+ and ability to interact with soluble and insoluble copper compounds makes it biotechnologically perspective.

INIS - International Nuclear Information System. CEA-users relations. Nuclear information in total freedom; INIS - International Nuclear Information System. Relations CEA utilisateurs. L'information nucleaire en toute liberte

Energy Technology Data Exchange (ETDEWEB)

Surmont, J.; Paillard, M.D.; Constant, A.; Guille, N.; Le Blanc, A.; Mouffron, O.; Anguise, P.; Jouve, J.J.; Lilin, A

2009-07-01

This poster, prepared for the seventh edition of the meetings of scientific and technical information professionals (RPIST, Nancy (France)), presents the principle of operation of the INIS system, based on a cooperative and decentralized preparation of the data which are centralized by the IAEA for the preparation of the INIS products: the database (on Internet and on CD/DVD-Rom), the collection of grey literature documents in full text (microfiches and CD/DVD-roms), and the multilingual thesaurus available in 7 different languages and under various formats. The poster presents these different products, and the role of the INIS members in the distribution of these products towards their national users. One insert presents the French INIS team of the CEA-Saclay and its daily work. (J.S.)

INIS - International Nuclear Information System. CEA-users relations. Nuclear information in total freedom

International Nuclear Information System (INIS)

Surmont, J.; Paillard, M.D.; Constant, A.; Guille, N.; Le Blanc, A.; Mouffron, O.; Anguise, P.; Jouve, J.J.; Lilin, A.

2009-01-01

This poster, prepared for the seventh edition of the meetings of scientific and technical information professionals (RPIST, Nancy (France)), presents the principle of operation of the INIS system, based on a cooperative and decentralized preparation of the data which are centralized by the IAEA for the preparation of the INIS products: the database (on Internet and on CD/DVD-Rom), the collection of grey literature documents in full text (microfiches and CD/DVD-roms), and the multilingual thesaurus available in 7 different languages and under various formats. The poster presents these different products, and the role of the INIS members in the distribution of these products towards their national users. One insert presents the French INIS team of the CEA-Saclay and its daily work. (J.S.)

Real-time high-resolution PC-based system for measurement of errors on compact disks

Science.gov (United States)

Tehranchi, Babak; Howe, Dennis G.

1994-10-01

Hardware and software utilities are developed to directly monitor the Eight-to-Fourteen (EFM) demodulated data bytes at the input of a CD player's Cross-Interleaved Reed-Solomon Code (CIRC) block decoder. The hardware is capable of identifying erroneous data with single-byte resolution in the serial data stream read from a Compact Disc by a CDD 461 Philips CD-ROM drive. In addition, the system produces graphical maps that show the physical location of the measured errors on the entire disc, or via a zooming and planning feature, on user selectable local disc regions.

Diffraction-based BioCD biosensor for point-of-care diagnostics

Science.gov (United States)

Choi, H.; Chang, C.; Savran, C.; Nolte, D.

2018-02-01

The BioCD platform technology uses spinning-disk interferometry to detect molecular binding to target molecular probes in biological samples. Interferometric configurations have included differential phase contrast and in-line quadrature detection. For the detection of extremely low analyte concentrations, nano- or microparticles can enhance the signal through background-free diffraction detection. Diffraction signal measurements on BioCD biosensors are achieved by forming gratings on a disc surface. The grating pattern was printed with biotinylated bovine serum albumin (BSA) and streptavidin coated beads were deployed. The diameter of the beads was 1 micron and strong protein bonding occurs between BSA and streptavidin-coated beads at the printed location. The wavelength for the protein binding detection was 635 nm. The periodic pattern on the disc amplified scattered light into the first-order diffraction position. The diffracted signal contains Mie scattering and a randomly-distributed-bead noise contributions. Variation of the grating pattern periodicity modulates the diffraction efficiency. To test multiple spatial frequencies within a single scan, we designed a fan-shaped grating to perform frequency filter multiplexing on a diffraction-based BioCD.

Spectrophotometry (by Barbara Sawrey and Gabriele Wienhausen)

Science.gov (United States)

Pringle, David L.

1998-08-01

Science Media: San Diego, 1997. 1-10 copies, 99 each; 11-20 copies, 69 each; 21+ copies, $49 each. (Note: CD operates with both Mac and PC.) Spectrophotometry is an interactive CD-ROM which introduces the basics of UV-visible spectrophotometry with some mention of infrared and other forms of spectrophotometry. A Macintosh System 7.5 or higher, CPU 68040 or Power PC processor, 6 megabytes of free RAM, 2.6 megabytes of free disk space, and 4X CD-ROM or faster are required.

Synthesis of CdS nanoparticles based on DNA network templates

International Nuclear Information System (INIS)

Yao Yong; Song Yonghai; Wang Li

2008-01-01

CdS nanoparticles have been successfully synthesized by using DNA networks as templates. The synthesis was carried out by first dropping a mixture of cadmium acetate and DNA on a mica surface for the formation of the DNA network template and then transferring the sample into a heated thiourea solution. The Cd 2+ reacted with thiourea at high temperature and formed CdS nanoparticles on the DNA network template. UV-vis spectroscopy, photoluminescence, x-ray diffraction and atomic force microscopy (AFM) were used to characterize the CdS nanoparticles in detail. AFM results showed that the resulted CdS nanoparticles were directly aligned on the DNA network templates and that the synthesis and assembly of CdS nanoparticles was realized in one step. CdS nanoparticles fabricated with this method were smaller than those directly synthesized in a thiourea solution and were uniformly aligned on the DNA networks. By adjusting the density of the DNA networks and the concentration of Cd 2+ , the size and density of the CdS nanoparticles could be effectively controlled and CdS nanoparticles could grow along the DNA chains into nanowires. The possible growth mechanism has also been discussed in detail

Scanner qualification with IntenCD based reticle error correction

Science.gov (United States)

Elblinger, Yair; Finders, Jo; Demarteau, Marcel; Wismans, Onno; Minnaert Janssen, Ingrid; Duray, Frank; Ben Yishai, Michael; Mangan, Shmoolik; Cohen, Yaron; Parizat, Ziv; Attal, Shay; Polonsky, Netanel; Englard, Ilan

2010-03-01

Scanner introduction into the fab production environment is a challenging task. An efficient evaluation of scanner performance matrices during factory acceptance test (FAT) and later on during site acceptance test (SAT) is crucial for minimizing the cycle time for pre and post production-start activities. If done effectively, the matrices of base line performance established during the SAT are used as a reference for scanner performance and fleet matching monitoring and maintenance in the fab environment. Key elements which can influence the cycle time of the SAT, FAT and maintenance cycles are the imaging, process and mask characterizations involved with those cycles. Discrete mask measurement techniques are currently in use to create across-mask CDU maps. By subtracting these maps from their final wafer measurement CDU map counterparts, it is possible to assess the real scanner induced printed errors within certain limitations. The current discrete measurement methods are time consuming and some techniques also overlook mask based effects other than line width variations, such as transmission and phase variations, all of which influence the final printed CD variability. Applied Materials Aera2TM mask inspection tool with IntenCDTM technology can scan the mask at high speed, offer full mask coverage and accurate assessment of all masks induced source of errors simultaneously, making it beneficial for scanner qualifications and performance monitoring. In this paper we report on a study that was done to improve a scanner introduction and qualification process using the IntenCD application to map the mask induced CD non uniformity. We will present the results of six scanners in production and discuss the benefits of the new method.

Dāvida Lodža „Mazā pasaule” un „Paradīzes jaunumi” kā piedzīvojumu romāni

OpenAIRE

Kaušakīte, Inessa

2007-01-01

Maģistra darbā „Deivida Lodža „Mazā pasaule” un „Paradīzes Jaunumi” kā piedzīvojumu romāni” mērķis ir pievērst uzmanību piedzīvojuma žanra dažādām īpatnībām mūsdienu angļu romānista darbos. Darbs arī atklāj postmodernā piedzīvojumu romāna varoņa rakstura īpatnības. Pirmā nodaļa izceļ klasiskā 16. gadsimta spāņu literatūras piedzīvojumu romāna svarīgākās īpatnības. Šī nodaļa pēta apstākļus, kas palīdzējuši žanra attīstībai Anglijā. Otrā nodaļa pievērš uzmanību Deivida Lodža liktenim, kas kā...

Quantitative variations of CD4 + CD25 + cells in Peking duckwhite ...

African Journals Online (AJOL)

Quantitative variations of CD4 + CD25 + cells in Peking duckwhite leghorn chimeras based on bone marrow mesenchymal stem cells. ... Tropical Journal of Pharmaceutical Research. Journal Home · ABOUT THIS JOURNAL · Advanced ...

[Five years of ROM in substance abuse treatment centres in the Netherlands].

Science.gov (United States)

Oudejans, S C C; Schippers, G M; Spits, M E; Stollenga, M; van den Brink, W

2012-01-01

Three substance abuse treatment centres set up a benchmarking project for routine outcome management (ROM) of structured cognitive behavioral treatments for outpatients with a substance use disorder. To present the results of five years benchmarking. All patients were included at intake and the follow-up assessment was performed by a call-center nine months later. Twice a year aggregated data were fed back to management and treatment teams. Since 2005, clinical outcome data, including substance abuse data, have been collected for more than half of all 15.786 treated patients. At follow-up, nine months after intake, 23% was abstinent, 28% reported moderate substance use and 49% reported excessive substance use. The Dutch centres for the treatment of substance abuse were successful in setting up ROM projects to monitor and compare the development and the effects of outpatient addiction treatments. The clinical results are acceptable and correspond to the results of the American project called match. It is not yet clear whether the biannual feedback of aggregated outcomes to management and treatment teams has contributed to the creation of learning organisations, but it has provided transparency and has made it possible for teams to learn from the outcomes.

LOYALTY – THE NUCLEUS OF BRAND CAPITAL. CASE STUDY: ROM CHOCOLATE BAR

Directory of Open Access Journals (Sweden)

Brindusa Mariana Amalancei

2013-12-01

Full Text Available It is considered that loyalty to the brand of some primary customers is the core of the brand capital. A brand, however, may have substantial value, which is given to it by its symbol and slogans, if it is continued with the purchase of a brand after the buyers have made a comparison with the competing products that have superior characteristics. Structured on several levels, which are each a different marketing challenge, the loyalty to the brand consists of many factors, among which the most important is the user experience. The paper aims to highlight, starting from a series of articles in online media, the manner in which a traditional Romanian brand, ROM chocolate bar, continuously repositions itself, attempting to maintain and even increase the loyalty of its consumers, as well as to answer the consumer’s authenticity, accessibility, credibility and modernity needs. Even though in specialized literature there are opinions according to which traditional brands are commonly old-fashioned or dull, ROM chocolate bar shows the opposite view, being considered a successful brand which is appreciated both at national and international levels.

CdTe Quantum Dots Embedded in Multidentate Biopolymer Based on Salep: Characterization and Optical Properties

Directory of Open Access Journals (Sweden)

Ghasem Rezanejade Bardajee

2013-01-01

Full Text Available This paper describes a novel method for surface modification of water soluble CdTe quantum dots (QDs by using poly(acrylic acid grafted onto salep (salep-g-PAA as a biopolymer. As-prepared CdTe-salep-g-PAA QDs were characterized by Fourier transform infrared (FT-IR spectrum, thermogravimetric (TG analysis, and transmission electron microscopy (TEM. The absorption and fluorescence emission spectra were measured to investigate the effect of salep-g-PAA biopolymer on the optical properties of CdTe QDs. The results showed that the optical properties of CdTe QDs were significantly enhanced by using salep-g-PAA-based biopolymer.

Using multimedia to link experts' views and derive common conclusions

DEFF Research Database (Denmark)

Howard, Rob

1997-01-01

Introductory paper to an issue of Automation in Construction edited by the author with papers from several contributors to the Building IT 2005 multimedia CD-ROM on the future of IT in the construction industry......Introductory paper to an issue of Automation in Construction edited by the author with papers from several contributors to the Building IT 2005 multimedia CD-ROM on the future of IT in the construction industry...

Fine-tuning of T-cell development by the CD3γ di-leucine-based TCR-sorting motif

DEFF Research Database (Denmark)

Lauritsen, Jens Peter Holst; Boding, Lasse; Buus, Terkild B

2015-01-01

The CD3γ di-leucine-based (diL) receptor-sorting motif plays a central role in TCR down-regulation and in clonal expansion of virus-specific T cells. However, the role of the CD3γ diL motif in T-cell development is not known. In this study, we show that protein kinase C-induced TCR down-regulatio......The CD3γ di-leucine-based (diL) receptor-sorting motif plays a central role in TCR down-regulation and in clonal expansion of virus-specific T cells. However, the role of the CD3γ diL motif in T-cell development is not known. In this study, we show that protein kinase C-induced TCR down...

Diagnostic instrumentation aboard ISS: just-in-time training for non-physician crewmembers

Science.gov (United States)

Foale, C. Michael; Kaleri, Alexander Y.; Sargsyan, Ashot E.; Hamilton, Douglas R.; Melton, Shannon; Martin, David; Dulchavsky, Scott A.

2005-01-01

INTRODUCTION: The performance of complex tasks on the International Space Station (ISS) requires significant preflight crew training commitments and frequent skill and knowledge refreshment. This report documents a recently developed "just-in-time" training methodology, which integrates preflight hardware familiarization and procedure training with an on-orbit CD-ROM-based skill enhancement. This "just-in-time" concept was used to support real-time remote expert guidance to complete ultrasound examinations using the ISS Human Research Facility (HRF). METHODS: An American and Russian ISS crewmember received 2 h of "hands on" ultrasound training 8 mo prior to the on-orbit ultrasound exam. A CD-ROM-based Onboard Proficiency Enhancement (OPE) interactive multimedia program consisting of memory enhancing tutorials, and skill testing exercises, was completed by the crewmember 6 d prior to the on-orbit ultrasound exam. The crewmember was then remotely guided through a thoracic, vascular, and echocardiographic examination by ultrasound imaging experts. RESULTS: Results of the CD-ROM-based OPE session were used to modify the instructions during a complete 35-min real-time thoracic, cardiac, and carotid/jugular ultrasound study. Following commands from the ground-based expert, the crewmember acquired all target views and images without difficulty. The anatomical content and fidelity of ultrasound video were adequate for clinical decision making. CONCLUSIONS: Complex ultrasound experiments with expert guidance were performed with high accuracy following limited preflight training and multimedia based in-flight review, despite a 2-s communication latency. In-flight application of multimedia proficiency enhancement software, coupled with real-time remote expert guidance, facilitates the successful performance of ultrasound examinations on orbit and may have additional terrestrial and space applications.

A new photoelectric ink based on nanocellulose/CdS quantum dots for screen-printing.

Science.gov (United States)

Tang, Aimin; Liu, Yuan; Wang, Qinwen; Chen, Ruisong; Liu, Wangyu; Fang, Zhiqiang; Wang, Lishi

2016-09-05

CdS quantum dots with excellent photoelectrical properties embedded in nanocellulose could be exploited for use in photoelectrical ink. In this work, nanocellulose/CdS quantum dot composites were fabricated by controlling the carboxylate content of the nanocellulose and the molar ratio of Cd(2+)/-COOH. New photoelectric inks were prepared based on the composites, in which the CdS quantum dots acted as the pigment and the nanocellulose as the binder. The results of the photocurrent of the composites showed that the photocurrent could be tailored by the carboxylate content and the molar ratio of Cd(2+)/-COOH. And the photocurrent could be as high as 2μA. The surface tension of the photoelectric ink was 27.80±0.03mN/m and its viscosity was 30.3mPas. The photoelectric ink was stable with excellent fluidity and rheology, it could therefore be applied to screen-printing and three-dimensional (3D) printing. Copyright © 2016 Elsevier Ltd. All rights reserved.

SEM REGRA NEM FREIOS - Loucura e criação na discussão romântica em torno do gênio

Directory of Open Access Journals (Sweden)

Yuri Cerqueira dos Anjos

2014-12-01

Full Text Available A relação entre genialidade e loucura, tópos bastante antigo, parece ganhar contornos peculiares no pensamento romântico. Inspirado, ultrassensível, isolado e visionário, o gênio romântico transita com certa frequência no campo semântico da loucura. Entre oráculo, profeta e louco, ele se caracteriza pela sua capacidade de transgredir o estado atual das coisas e criar um novo mundo de possibilidades e experiências. Nesse sentido, exploraremos no presente artigo alguns aspectos dessa relação entre o gênio e o louco no contexto do debate romântico francês do início do século XIX e no livro William Shakespeare, de Victor Hugo.

CdS nanobubbles and Cd-DMS nanosheets: solvothermal synthesis and formation mechanism.

Science.gov (United States)

Feng, Miao; Zhan, Hongbing

2013-02-01

CdS nanobubbles and Cd-DMS nanosheets have been prepared by a solvothermal method from a solution of Cd2+ in dimethyl sulfoxide in the absence of elemental S. A formation mechanism for the nanobubble morphology arising during the CdS nanocrystal growth has been proposed, based on the results of transmission electron microscopy and photoluminescence spectrophotometry. The correlation of the morphology with reaction time was also suggested, and may be applicable to the solvothermal synthesis of other nanomaterials.

Feasibility of a CdTe-based SPECT for high-resolution low-dose small animal imaging: a Monte Carlo simulation study

International Nuclear Information System (INIS)

Park, S-J; Yu, A R; Lee, Y-J; Kim, Y-S; Kim, H-J

2014-01-01

Dedicated single-photon-emission computed tomography (SPECT) systems based on pixelated semiconductors such as cadmium telluride (CdTe) are in development to study small animal models of human disease. In an effort to develop a high-resolution, low-dose system for small animal imaging, we compared a CdTe-based SPECT system and a conventional NaI(Tl)-based SPECT system in terms of spatial resolution, sensitivity, contrast, and contrast-to-noise ratio (CNR). In addition, we investigated the radiation absorbed dose and calculated a figure of merit (FOM) for both SPECT systems. Using the conventional NaI(Tl)-based SPECT system, we achieved a spatial resolution of 1.66 mm at a 30 mm source-to-collimator distance, and a resolution of 2.4-mm hot-rods. Using the newly-developed CdTe-based SPECT system, we achieved a spatial resolution of 1.32 mm FWHM at a 30 mm source-to-collimator distance, and a resolution of 1.7-mm hot-rods. The sensitivities at a 30 mm source-to-collimator distance were 115.73 counts/sec/MBq and 83.38 counts/sec/MBq for the CdTe-based SPECT and conventional NaI(Tl)-based SPECT systems, respectively. To compare quantitative measurements in the mouse brain, we calculated the CNR for images from both systems. The CNR from the CdTe-based SPECT system was 4.41, while that from the conventional NaI(Tl)-based SPECT system was 3.11 when the injected striatal dose was 160 Bq/voxel. The CNR increased as a function of injected dose in both systems. The FOM of the CdTe-based SPECT system was superior to that of the conventional NaI(Tl)-based SPECT system, and the highest FOM was achieved with the CdTe-based SPECT at a dose of 40 Bq/voxel injected into the striatum. Thus, a CdTe-based SPECT system showed significant improvement in performance compared with a conventional system in terms of spatial resolution, sensitivity, and CNR, while reducing the radiation dose to the small animal subject. Herein, we discuss the feasibility of a CdTe-based SPECT system for high

Nanomechanical recognition of prognostic biomarker suPAR with DVD-ROM optical technology

International Nuclear Information System (INIS)

Bache, Michael; Bosco, Filippo G; Brøgger, Anna L; Frøhling, Kasper B; Boisen, Anja; Alstrøm, Tommy Sonne; Hwu, En-Te; Chen, Ching-Hsiu; Hwang, Ing-Shouh; Eugen-Olsen, Jesper

2013-01-01

In this work the use of a high-throughput nanomechanical detection system based on a DVD-ROM optical drive and cantilever sensors is presented for the detection of urokinase plasminogen activator receptor inflammatory biomarker (uPAR). Several large scale studies have linked elevated levels of soluble uPAR (suPAR) to infectious diseases, such as HIV, and certain types of cancer. Using hundreds of cantilevers and a DVD-based platform, cantilever deflection response from antibody–antigen recognition is investigated as a function of suPAR concentration. The goal is to provide a cheap and portable detection platform which can carry valuable prognostic information. In order to optimize the cantilever response the antibody immobilization and unspecific binding are initially characterized using quartz crystal microbalance technology. Also, the choice of antibody is explored in order to generate the largest surface stress on the cantilevers, thus increasing the signal. Using optimized experimental conditions the lowest detectable suPAR concentration is currently around 5 nM. The results reveal promising research strategies for the implementation of specific biochemical assays in a portable and high-throughput microsensor-based detection platform. (paper)

Perspective on One Decade of Laser Propulsion Research at the Air Force Research Laboratory, November 1995-2005 (DVD)

National Research Council Canada - National Science Library

2007-01-01

.... PHYSICAL DESCRIPTION: 1 DVD-ROM and 1 CD-ROM; 4 3/4 in.; 395 MB. ABSTRACT: A short film and presentation on laser propulsion research at the Air Force Research Laboratory, spanning November 1995 through October 2005...

Photovoltaic performance of a Cd1−xMgxTe/CdS top-cell structure

International Nuclear Information System (INIS)

Martinez, Omar S.; Regalado-Pérez, E.; Mathews, N.R.; Morales, Erik R.; Reyes-Coronado, David; Galvez, Geovanni Hernández; Mathew, Xavier

2015-01-01

In this paper we report the progress in developing a wide band gap alloy material based on CdTe to use as the top-cell absorber in tandem solar cells. High photovoltaic performance for a Cd 1−x Mg x Te/CdS top-cell was achieved by tuning the composition of the Cd 1−x Mg x Te film, and optimizing the device processing. We have carried out studies on the effect of vapor chloride treatment of the Cd 1−x Mg x Te/CdS device and the thermal annealing of the Cu/Au contacts on the opto-electronic properties of the device. With improved contact processing and post deposition treatments, we were able to achieve 9.3% efficiency for a 1.6 eV band gap top-cell; Cd 1−x Mg x Te/CdS on conductive glass substrate. - Highlights: • Cd 1−x Mg x Te films obtained by co-evaporation of CdTe and Mg • Band gap of Cd 1−x Mg x Te can be easily tuned by verifying x. • Band gap of Cd 1−x Mg x Te is stable only for short annealing durations. • Obtained efficiency of a Cd 1−x Mg x Te based device with a band gap of 1.6 eV is 9.3%

A pixellated gamma-camera based on CdTe detectors clinical interests and performances

CERN Document Server

Chambron, J; Eclancher, B; Scheiber, C; Siffert, P; Hage-Ali, M; Regal, R; Kazandjian, A; Prat, V; Thomas, S; Warren, S; Matz, R; Jahnke, A; Karman, M; Pszota, A; Németh, L

2000-01-01

A mobile gamma camera dedicated to nuclear cardiology, based on a 15 cmx15 cm detection matrix of 2304 CdTe detector elements, 2.83 mmx2.83 mmx2 mm, has been developed with a European Community support to academic and industrial research centres. The intrinsic properties of the semiconductor crystals - low-ionisation energy, high-energy resolution, high attenuation coefficient - are potentially attractive to improve the gamma-camera performances. But their use as gamma detectors for medical imaging at high resolution requires production of high-grade materials and large quantities of sophisticated read-out electronics. The decision was taken to use CdTe rather than CdZnTe, because the manufacturer (Eurorad, France) has a large experience for producing high-grade materials, with a good homogeneity and stability and whose transport properties, characterised by the mobility-lifetime product, are at least 5 times greater than that of CdZnTe. The detector matrix is divided in 9 square units, each unit is composed ...

Rojas Zorrilla ante la crítica romántica

Directory of Open Access Journals (Sweden)

Pedraza Jiménez, Felipe B

2007-06-01

Full Text Available To Romantic Criticism, Rojas Zorrilla’s fame becomed obscure by the figure of his contemporary, friend and collaborator, Pedro Calderón de la Barca. This logical situation is clearly evident in the great german critics: Rojas Zorrilla is scarcely mentioned by the Schlegel brothers. To other historians he occupied a secondary place and the only exception was Johann Ludwig Tieck, who exalted his works even above Calderón masterpieces. It can be affirmed that Rojas Zorrilla reception was irregular. If we examine Musso Valiente’s library, Agustín Durán’s Discurso, and the romantic period editions, we will find some interest in his figure and that it was situated in a secondary place in relation to our great theater. It seems clear that Martínez de la Rosa and Alberto Lista were the critics who pay more attention to him. Martínez de la Rosa established an approach based in the neoclassic topics about our writer, meanwhile Alberto Lista developed a closer and original reading, specially centered in the poet’s tragic dimension and elements that, from his point of view, anticipated romantic Aesthetics. Rojas Zorrilla inclusion in romantic Literary Histories, and his edition in the «Biblioteca de Autores Españoles», prepared by Mesonero Romanos, make him enter the canon among the «six great stars» in Spanish Golden Age Theater.Para la crítica romántica, la fama de Rojas Zorrilla quedó oscurecida, de forma perfectamente lógica, por la de su coetáneo, amigo y colaborador don Pedro Calderón de la Barca. Esta situación es muy patente en los grandes críticos alemanes. Los hermanos Schlegel apenas citan a nuestro dramaturgo. Otros historiadores le conceden un lugar secundario, con la excepción de Johann Ludwig Tieck, que lo exaltó incluso por encima del autor de La vida es sueño. La recepción de su obra en España fue irregular. Del análisis de la biblioteca y escritos de Musso Valiente, del discurso de Agustín Durán, de las

Evaluation of Stem Cell Markers, CD44/CD24 in Breast Cancer Cell Lines

Directory of Open Access Journals (Sweden)

Masoud Hashemi Arabi

2014-05-01

Four breast cancer cell lines, MCF-7 ، T47D ، MDA-MB231 and MDA-MB468 were purchased from National cell Bank of Iran based in Iran Pasture Institute and were cultured in high glucose DMEM supplemented with 10% FCS. Cells were stained with antiCD44-PE and antiCD24-FITC antibodies and Status of CD44 and CD24 as markers of breast cancer stem cells were evaluated using flow cytometer and fluorescent microscopy.Evaluation of CD44 and CD24 as markers of breast cancer stem cells showed that MDA-MB231 with 97±1.2% CD44+/CD24-/low cells is significantly different from the others that they were mainly CD44 and CD24 positive cells(p

Toward the optimization of PC-based training

Science.gov (United States)

Cho, Kohei; Murai, Shunji

Since 1992, the National Space Development Agency of Japan (NASDA) and the Economic and Social Commission for Asia and the Pacific (ESCAP) have been co-organising the Regional Remote Sensing Seminar on Tropical Ecosystem Management (Program Chairman: Prof. Shunji Murai) every year in some country in Asia. In these seminars, the members of the ISPRS Working Group VI/2 'Computer Assisted Teaching' have been performing a PC-based hands-on-training on remote sensing and GIS for beginners. The main objective of the training was to transfer not only knowledge but also the technology of remote sensing and GIS to the beginners. The software and CD-ROM data set provided at the training were well designed not only for training but also for practical data analysis. This paper presents an outline of the training and discusses the optimisation of PC-based training for remote sensing and GIS.

Abordagens do amor romântico: aspectos históricos, sociais e literários

Directory of Open Access Journals (Sweden)

Luana Grasiela Schonarth

2015-06-01

Full Text Available O presente estudo vincula-se ao projeto de pesquisa Narrativas e conhecimentos: especificidades teóricas e constituição de sentido, coordenado pela Prof.ª Dra. Eunice Terezinha Piazza Gai. Considerando os caminhos cursados no desenvolvimento da pesquisa, utilizamos o tema do amor para refletir sobre os possíveis conhecimentos que o processo narrativo propicia, os aspectos históricos e sociais nos quais a temática foi abordada na literatura, assim como um resgate de informações acerca das origens do tema e personagens consolidados nos romances românticos. Nessa perspectiva, delimitamos o estudo entre os amores irrealizados, os impasses responsáveis pelos impedimentos amorosos, bem como os conflitos entre a paixão e o casamento nas narrativas românticas. Para bem fundamentar esta pesquisa, tomamos o mito considerado matriz das histórias de amor, o próprio nascimento da paixão na literatura ocidental: Tristão e Isolda. O mito apresenta a visão do amor cortês e as contradições que se manifestaram desde a segunda metade do século XII entre a regra cavalheiresca e os costumes feudais. Diante da teoria do amor, abstraída do mito do amor romântico, partimos para a literatura do século XIX, considerando a presença dos amores não correspondidos. Nesta etapa, analisamos o romance de Balzac, Eugênia Grandet, que se torna exemplo da irrealização amorosa na literatura, vivida de modo mais contundente pela personagem que intitula a obra. A escolha dessa narrativa, para a análise do amor-paixão, deve-se ao fato de que o casamento é tratado como mero interesse financeiro, desconsiderando todo e qualquer envolvimento amoroso entre o casal em questão: Eugênia e Charles. Tratamos, pois, desta pluralidade significativa, deste amplo caminho trilhado não só pela literatura, mas por todos aqueles que se deixam despertar pela eternidade e fascínio dos romances românticos.

A DNA vaccine encoding multiple HIV CD4 epitopes elicits vigorous polyfunctional, long-lived CD4+ and CD8+ T cell responses.

Directory of Open Access Journals (Sweden)

Daniela Santoro Rosa

Full Text Available T-cell based vaccines against HIV have the goal of limiting both transmission and disease progression by inducing broad and functionally relevant T cell responses. Moreover, polyfunctional and long-lived specific memory T cells have been associated to vaccine-induced protection. CD4(+ T cells are important for the generation and maintenance of functional CD8(+ cytotoxic T cells. We have recently developed a DNA vaccine encoding 18 conserved multiple HLA-DR-binding HIV-1 CD4 epitopes (HIVBr18, capable of eliciting broad CD4(+ T cell responses in multiple HLA class II transgenic mice. Here, we evaluated the breadth and functional profile of HIVBr18-induced immune responses in BALB/c mice. Immunized mice displayed high-magnitude, broad CD4(+/CD8(+ T cell responses, and 8/18 vaccine-encoded peptides were recognized. In addition, HIVBr18 immunization was able to induce polyfunctional CD4(+ and CD8(+ T cells that proliferate and produce any two cytokines (IFNγ/TNFα, IFNγ/IL-2 or TNFα/IL-2 simultaneously in response to HIV-1 peptides. For CD4(+ T cells exclusively, we also detected cells that proliferate and produce all three tested cytokines simultaneously (IFNγ/TNFα/IL-2. The vaccine also generated long-lived central and effector memory CD4(+ T cells, a desirable feature for T-cell based vaccines. By virtue of inducing broad, polyfunctional and long-lived T cell responses against conserved CD4(+ T cell epitopes, combined administration of this vaccine concept may provide sustained help for CD8(+ T cells and antibody responses- elicited by other HIV immunogens.

A Fuel-Sensitive Reduced-Order Model (ROM) for Piston Engine Scaling Analysis

Science.gov (United States)

2017-09-29

of high Reynolds number nonreacting and reacting JP-8 sprays in a constant pressure flow vessel with a detailed chemistry approach . J Energy Resour...for rapid grid generation applied to in-cylinder diesel engine simulations. Society of Automotive Engineers ; 2007 Apr. SAE Technical Paper No.: 2007...ARL-TR-8172 ● Sep 2017 US Army Research Laboratory A Fuel-Sensitive Reduced-Order Model (ROM) for Piston Engine Scaling Analysis

Performance evaluation of a hand-held, semiconductor (CdZnTe)-based gamma camera

CERN Document Server

Abe, A; Lee, J; Oka, T; Shizukuishi, K; Kikuchi, T; Inoue, T; Jimbo, M; Ryuo, H; Bickel, C

2003-01-01

We have designed and developed a small field of view gamma camera, the eZ SCOPE, based on use of a CdZnTe semiconductor. This device utilises proprietary signal processing technology and an interface to a computer-based imaging system. The purpose of this study was to evaluate the performance of the eZ scope in comparison with currently employed gamma camera technology. The detector is a single wafer of 5-mm-thick CdZnTe that is divided into a 16 x 16 array (256 pixels). The sensitive area of the detector is a square of dimension 3.2 cm. Two parallel-hole collimators are provided with the system and have a matching (256 hole) pattern to the CdZnTe detector array: a low-energy, high-resolution parallel-hole (LEHR) collimator fabricated of lead and a low-energy, high-sensitivity parallel-hole (LEHS) collimator fabricated of tungsten. Performance measurements and the data analysis were done according to the procedures of the NEMA standard. We also studied the long-term stability of the system with continuous use...

Multifunctional Analysis of CD4+ T-Cell Response as Immune-Based Model for Tuberculosis Detection

Directory of Open Access Journals (Sweden)

Miriam Lichtner

2015-01-01

Full Text Available Mono- and multifunctional specific CD4+ and CD8+ T-cell responses were evaluated to improve the immune-based detection of active tuberculosis (TB and latent infection (LTBI. We applied flow cytometry to investigate cytokines profile (IFN-γ, TNF-α, and IL-2 of T cells after stimulation with TB antigens in 28 TB-infected subjects (18 active TB and 10 LTBI and 10 uninfected controls. Cytokines production by CD4+ T cells at single-cell levels was higher in TB-infected subjects than uninfected controls P0.45%, it was possible to differentiate TB-infected (>0.45% by uninfected subjects (0.182%. The magnitude of CD8+ T-cell responses showed no differences between active TB and LTBI. Multifunctional CD4+ T-cell responses could have the potential to identify at single time point subjects without TB infection and patients having active or latent TB.

A viral long terminal repeat expressed in CD4+CD8+ precursors is downregulated in mature peripheral CD4-CD8+ or CD4+CD8- T cells.

OpenAIRE

Paquette, Y; Doyon, L; Laperrière, A; Hanna, Z; Ball, J; Sekaly, R P; Jolicoeur, P

1992-01-01

The long terminal repeat from a thymotropic mouse mammary tumor virus variant, DMBA-LV, was used to drive the expression of two reporter genes, murine c-myc and human CD4, in transgenic mice. Expression was observed specifically in thymic immature cells. Expression of c-myc in these cells induced oligoclonal CD4+ CD8+ T-cell thymomas. Expression of human CD4 was restricted to thymic progenitor CD4- CD8- and CD4+ CD8+ T cells and was shut off in mature CD4+ CD8- and CD4- CD8+ T cells, known to...

Volcanoes of the Wrangell Mountains and Cook Inlet region, Alaska: selected photographs

Science.gov (United States)

Neal, Christina A.; McGimsey, Robert G.; Diggles, Michael F.

2001-01-01

Alaska is home to more than 40 active volcanoes, many of which have erupted violently and repeatedly in the last 200 years. This CD-ROM contains 97 digitized color 35-mm images which represent a small fraction of thousands of photographs taken by Alaska Volcano Observatory scientists, other researchers, and private citizens. The photographs were selected to portray Alaska's volcanoes, to document recent eruptive activity, and to illustrate the range of volcanic phenomena observed in Alaska. These images are for use by the interested public, multimedia producers, desktop publishers, and the high-end printing industry. The digital images are stored in the 'images' folder and can be read across Macintosh, Windows, DOS, OS/2, SGI, and UNIX platforms with applications that can read JPG (JPEG - Joint Photographic Experts Group format) or PCD (Kodak's PhotoCD (YCC) format) files. Throughout this publication, the image numbers match among the file names, figure captions, thumbnail labels, and other references. Also included on this CD-ROM are Windows and Macintosh viewers and engines for keyword searches (Adobe Acrobat Reader with Search). At the time of this publication, Kodak's policy on the distribution of color-management files is still unresolved, and so none is included on this CD-ROM. However, using the Universal Ektachrome or Universal Kodachrome transforms found in your software will provide excellent color. In addition to PhotoCD (PCD) files, this CD-ROM contains large (14.2'x19.5') and small (4'x6') screen-resolution (72 dots per inch; dpi) images in JPEG format. These undergo downsizing and compression relative to the PhotoCD images.

Transcriptomic changes during maize roots development responsive to Cadmium (Cd) pollution using comparative RNAseq-based approach

International Nuclear Information System (INIS)

Peng, Hua; He, Xiujing; Gao, Jian; Ma, Haixia; Zhang, Zhiming; Shen, Yaou; Pan, Guangtang; Lin, Haijian

2015-01-01

The heavy metal cadmium (Cd), acts as a widespread environmental contaminant, which has shown to adversely affect human health, food safety and ecosystem safety in recent years. However, research on how plant respond to various kinds of heavy metal stress is scarcely reported, especially for understanding of complex molecular regulatory mechanisms and elucidating the gene networks of plant respond to Cd stress. Here, transcriptomic changes during Mo17 and B73 seedlings development responsive to Cd pollution were investigated and comparative RNAseq-based approach in both genotypes were performed. 115 differential expression genes (DEGs) with significant alteration in expression were found co-modulated in both genotypes during the maize seedling development; of those, most of DGEs were found comprised of stress and defense responses proteins, transporters, as well as transcription factors, such as thaumatin-like protein, ZmOPR2 and ZmOPR5. More interestingly, genotype-specific transcriptional factors changes induced by Cd stress were found contributed to the regulatory mechanism of Cd sensitivity in both different genotypes. Moreover, 12 co-expression modules associated with specific biological processes or pathways (M1 to M12) were identified by consensus co-expression network. These results will expand our understanding of complex molecular mechanism of response and defense to Cd exposure in maize seedling roots. - Highlights: • Transcriptomic changes responsive to Cd pollution using comparative RNAseq-based approach. • 115 differential expression genes (DEGs) were found co-modulated in both genotypes. • Most of DGEs belong to stress and defense responses proteins, transporters, transcription factors. • 12 co-expression modules associated with specific biological processes or pathways. • Genotype-specific transcriptional factors changes induced by Cd stress were found

Transcriptomic changes during maize roots development responsive to Cadmium (Cd) pollution using comparative RNAseq-based approach

Energy Technology Data Exchange (ETDEWEB)

Peng, Hua [Key Laboratory of Biology and Genetic Improvement of Maize in Southwest Region, Ministry of Agriculture, Maize Research Institute, Sichuan Agricultural University, Wenjiang, Sichuan, 611130 (China); Sichuan Tourism College, Chengdu, 610000, Sichuan (China); He, Xiujing [Key Laboratory of Biology and Genetic Improvement of Maize in Southwest Region, Ministry of Agriculture, Maize Research Institute, Sichuan Agricultural University, Wenjiang, Sichuan, 611130 (China); Gao, Jian [Institute of Pathology and Southwest Cancer Center, Southwest Hospital, Third Military Medical University, Key Laboratory of Tumor Immunopathology, Ministry of Education of China, Chongqing (China); Ma, Haixia; Zhang, Zhiming; Shen, Yaou [Key Laboratory of Biology and Genetic Improvement of Maize in Southwest Region, Ministry of Agriculture, Maize Research Institute, Sichuan Agricultural University, Wenjiang, Sichuan, 611130 (China); Pan, Guangtang, E-mail: pangt@sicau.edu.cn [Key Laboratory of Biology and Genetic Improvement of Maize in Southwest Region, Ministry of Agriculture, Maize Research Institute, Sichuan Agricultural University, Wenjiang, Sichuan, 611130 (China); Lin, Haijian, E-mail: linhj521@gmail.com [Key Laboratory of Biology and Genetic Improvement of Maize in Southwest Region, Ministry of Agriculture, Maize Research Institute, Sichuan Agricultural University, Wenjiang, Sichuan, 611130 (China)

2015-09-04

The heavy metal cadmium (Cd), acts as a widespread environmental contaminant, which has shown to adversely affect human health, food safety and ecosystem safety in recent years. However, research on how plant respond to various kinds of heavy metal stress is scarcely reported, especially for understanding of complex molecular regulatory mechanisms and elucidating the gene networks of plant respond to Cd stress. Here, transcriptomic changes during Mo17 and B73 seedlings development responsive to Cd pollution were investigated and comparative RNAseq-based approach in both genotypes were performed. 115 differential expression genes (DEGs) with significant alteration in expression were found co-modulated in both genotypes during the maize seedling development; of those, most of DGEs were found comprised of stress and defense responses proteins, transporters, as well as transcription factors, such as thaumatin-like protein, ZmOPR2 and ZmOPR5. More interestingly, genotype-specific transcriptional factors changes induced by Cd stress were found contributed to the regulatory mechanism of Cd sensitivity in both different genotypes. Moreover, 12 co-expression modules associated with specific biological processes or pathways (M1 to M12) were identified by consensus co-expression network. These results will expand our understanding of complex molecular mechanism of response and defense to Cd exposure in maize seedling roots. - Highlights: • Transcriptomic changes responsive to Cd pollution using comparative RNAseq-based approach. • 115 differential expression genes (DEGs) were found co-modulated in both genotypes. • Most of DGEs belong to stress and defense responses proteins, transporters, transcription factors. • 12 co-expression modules associated with specific biological processes or pathways. • Genotype-specific transcriptional factors changes induced by Cd stress were found.

Regulatory function of cytomegalovirus-specific CD4+CD27-CD28- T cells

International Nuclear Information System (INIS)

Tovar-Salazar, Adriana; Patterson-Bartlett, Julie; Jesser, Renee; Weinberg, Adriana

2010-01-01

CMV infection is characterized by high of frequencies of CD27 - CD28 - T cells. Here we demonstrate that CMV-specific CD4 + CD27 - CD28 - cells are regulatory T cells (T R ). CD4 + CD27 - CD28 - cells sorted from CMV-stimulated PBMC of CMV-seropositive donors inhibited de novo CMV-specific proliferation of autologous PBMC in a dose-dependent fashion. Compared with the entire CMV-stimulated CD4 + T-cell population, higher proportions of CD4 + CD27 - CD28 - T R expressed FoxP3, TGFβ, granzyme B, perforin, GITR and PD-1, lower proportions expressed CD127 and PD1-L and similar proportions expressed CD25, CTLA4, Fas-L and GITR-L. CMV-CD4 + CD27 - CD28 - T R expanded in response to IL-2, but not to CMV antigenic restimulation. The anti-proliferative effect of CMV-CD4 + CD27 - CD28 - T R significantly decreased after granzyme B or TGFβ inhibition. The CMV-CD4 + CD27 - CD28 - T R of HIV-infected and uninfected donors had similar phenotypes and anti-proliferative potency, but HIV-infected individuals had higher proportions of CMV-CD4 + CD27 - CD28 - T R . The CMV-CD4 + CD27 - CD28 - T R may contribute to the downregulation of CMV-specific and nonspecific immune responses of CMV-infected individuals.

Home Learning, Technology, and Tomorrow's Workplace.

Science.gov (United States)

Rieseberg, Rhonda L.

1995-01-01

Discusses characteristics and trends of home schools and workplaces. Use of computers and computer applications (CD-ROMS, interactive software, and networking) in home schooling provides a compatible environment for future home-based businesses and telecommuting trends. Sidebars include information on home schools on line; standardized test…

Studies in CdSe/CdS nanophosphors

International Nuclear Information System (INIS)

Chander, Harish

2006-01-01

Nanophosphors, also known as quantum dots, are being studied vigorously as these show enhanced efficiency and performance with great potential for tailoring properties. Nano size of these materials is responsible for opening novel applications everyday. Thin film light emitting devices, high definition TV, non-linear optical devices, ultra sensitive detectors and new white light sources are just few to mention. A lot of effort is being put in for using nanophosphors as fluorescent labels in biological applications. Many nanophosphors (quantum dots - QDs) of CdSe, CdS and combinations thereof exhibiting very high quality have been synthesised and studied. Quantum yield as high as 85% and a peaked emission have been reported. The potential of these materials has convinced the world that future belongs to them and serious attention needs to be diverted in research and development of these. In the present work, an attempt is made to review important studies made in the field of CdS/CdSe based nanophosphors with significant observations and results. Various upcoming applications of the family are highlighted. (author)

Norma Z39.50, actualidad, posibilidades. ¿Es necesario un cambio de actitud?

Directory of Open Access Journals (Sweden)

de la Rosa Piñero, A.

1998-12-01

Full Text Available Z39.50 standard based systems technology offers many quite promising possibilities for the future: systems connectivity, retrieval of high structured information, redefinition of applications (as search engines, agents and so forth, integration within proprietary software, online or CD-ROM publishing systems, protocols... However, the situation nowadays is very little advantageous in order to develop Z39.50 based systems. This paper analyses the range of possibilities offered by the mentioned standard

La tecnología de los sistemas basados en la norma Z39.50 ofrece numerosas posibilidades, a priori bastante prometedoras. Conectividad de sistemas, recuperación de información muy estructurada, redefinición de aplicaciones (robots de búsqueda, agentes..., integración con sistemas propietarios, edición online y CD-ROM, protocolos... Sin embargo, en la actualidad se está favoreciendo muy poco el desarrollo de sistemas basados en esta norma. En este artículo se analizan las diversas posibilidades que ofrece la misma.

Research and development of CdTe based thin film PV solar cells

Science.gov (United States)

Diso, Dahiru Garba

The motivation behind this research is to bring cheap, low-cost and clean energy technologies to the society. Colossal use of fossil fuel has created noticeable pollution problems contributing to climate change and health hazards. Silicon based solar cells have dominated the market but it is cost is high due to the manufacturing process. Therefore, the way forward is to develop thin films solar cells using low-cost attractive materials, grown by cheaper, scalable and manufacturable techniques.The aim and objectives of this work is to develop low-cost, high efficiency solar cell using electrodeposition (ED) technique. The material layers include CdS and ZnTe as the window materials, while the absorber material is CdTe. Fabricating a suitable devices for solar energy conversion (i.e. glass/conducting glass/window material/absorber material/metal) structure. Traditional way of fabricating this structure is to grow window material (CdS) using chemical bath deposition (CBD) and absorber material (CdTe) using electrodeposition. However, CBD is a batch process and therefore creates large volumes of Cd-containing waste solutions each time adding high cost in manufacturing process. This research programme is therefore on development of an "All ED-solar cells" structure.Material studies were carried out using photoelectrochemical (PEC) studies, UV-Vis spectrophotometry, X-ray diffraction (XRD), X-ray fluorescence (XRF), scanning electron microscopy (SEM), atomic force microscopy (AFM), Raman spectroscopy and X-ray photoelectron spectroscopy (XPS). Furthermore, the electrical characterisation of fully fabricated devices was performed using current-voltage (I-V) and capacitance-voltage (C-V) measurements.This research programme has demonstrated that CdS and ZnTe window materials can be electrodeposited and used in thin film solar cell devices. The CdS electrolytic bath can be used for a period of 7 months without discarding it like in the CBD process which usually has life

Marketing of Online and CD-ROM Databases.

Science.gov (United States)

King, Carol; Oppenheim, Charles

1994-01-01

A survey of 20 British electronic information vendors found that 95% considered marketing important and suggested that it is likely to become more intensive and aggressive as competition increases in the information industry. Analyzed advertisements from professional journals and direct mail literature for readability, structure, and information…

Pricing Software and Information on CD-ROM.

Science.gov (United States)

Gibbins, Patrick

1987-01-01

Examines the relationships between purchases of optical data disk products, publishers, and software suppliers. The discussion covers current pricing strategies for optical data disk software and information products, and possible future developments in marketing and pricing. (CLB)

The Collection Menasseh Ben Israel, CD-rom

NARCIS (Netherlands)

Haas, de J.J.M.; Offenberg, A.K.; Ootjers, M.G.

1998-01-01

The Bibliotheca Rosenthaliana, Department of Judaica and Hebraica, Amsterdam University Library, harbours many unique research collections. One of the most prominent consists of the editions printed in the seventeenth century by Menasseh Ben Israel (1604), who established the first Hebrew printing

Braiding simulation for TRM preforms (CD-ROM)

NARCIS (Netherlands)

Akkerman, Remko; Villa Rodriguez, B.H.

2006-01-01

Braiding is a manufacturing process that is increasingly being used to manufacture pre-forms for Resin Transfer Moulding. A fast simulation method is presented for the prediction of the fibre distribution on complex braided parts and complex kinetic situations (e.g. changes in velocity,

Korelasi Kadar Feritin dengan Jumlah CD4, CD8, dan Rasio CD4/CD8 pada Penyandang Talasemia Mayor Anak

Directory of Open Access Journals (Sweden)

Bonnie Arseno

2017-11-01

Hasil. Didapatkan jumlah CD4 absolut, CD4%, CD8 absolut dan rasio CD4/CD8 menurun. Selain itu, terdapat jumlah CD4 absolut, CD8 absolut dan CD8% meningkat. Pada kelompok usia ≤5 tahun, korelasi kadar feritin dengan CD8 absolut, CD8%, dan rasio CD4/CD8 berturut-turut menghasilkan koefisien korelasi 0,691, 0,557, -0,680, dan p<0,05. Sementara pada kelompok lama terapi ≤5 tahun korelasi kadar feritin dengan CD8 absolut, CD8%, dan rasio CD4/CD8 menghasilkan koefisien korelasi 0,709, 0,571, -0,726 dengan p<0,05. Kesimpulan. Tidak terdapat korelasi antara kadar feritin dengan jumlah CD4, CD8, rasio CD4/CD8. Peningkatan kadar feritin akan diikuti dengan peningkatan jumlah CD8 absolut dan CD8%, serta penurunan rasio CD4/CD8 pada penyandang talasemia mayor anak berdasar atas usia dan lama terapi ≤5 tahun.

Asociación entre relaciones románticas y la calidad de sueño percibida por jóvenes universitarios

OpenAIRE

EcheverrÍa-Palacio, Carlos-Mario

2013-01-01

Introducción: Uno de los aspectos con mayor variación durante la adolescencia es el sueño, el cual se ve afectado por factores biológicos así como por los estados afectivos y emocionales. En esta etapa, los individuos establecen sus primeras relaciones sentimentales románticas, vínculos esenciales para la maduración de las relaciones sociales y psicosexuales. Este trabajo busca determinar la asociación existente entre las relaciones sentimentales románticas y sus características, con la calid...

Multi-terminal Two-color ZnCdSe/ZnCdMgSe Based Quantum-well Infrared Photodetector

Science.gov (United States)

Kaya, Yasin; Ravikumar, Arvind; Chen, Guopeng; Tamargo, Maria C.; Shen, Aidong; Gmachl, Claire

Target recognition and identification applications benefits from two-color infrared (IR) detectors in the mid and long-wavelength IR regions. Currently, InGaAs/AlGaAs and GaAs/AlGaAs multiple quantum wells (QWs) grown on GaAs substrate are the most commonly used two-color QW IR photodetectors (QWIPs). However, the lattice-mismatch and the buildup of strain limit the number of QWs that can be grown, in turn increasing the dark current noise, and limiting the device detectivity.In this work, we report on two-color QWIPs based on the large conduction band offset (~1.12ev) ZnCdSe/ZnCdMgSe material system lattice matched to InP. QWIPs were designed based on a bound to quasi-bound transition, centered at 4 μm and 7 μm and each QW is repeated 50 times to eliminate the high dark current and a contact layer is inserted between the two stacks of QWs for independent electrical contacts. Wafers are processed into two step rectangular mesas by lithography and wet etching. Experiments showed absorption spectra centered at 4.9 μm and 7.6 μm at 80 K and the full width at half maximums were Δλ / λ = 21 % and Δλ / λ = 23 % , respectively. Current work studies the Johnson and the background noise limited detectivities of these QWIPs. Current address: School of Earth, Energy and Environmental Sciences, Stanford, CA 94305, USA.

Heterogeneity of Human Neutrophil CD177 Expression Results from CD177P1 Pseudogene Conversion.

Directory of Open Access Journals (Sweden)

Zuopeng Wu

2016-05-01

Full Text Available Most humans harbor both CD177neg and CD177pos neutrophils but 1-10% of people are CD177null, placing them at risk for formation of anti-neutrophil antibodies that can cause transfusion-related acute lung injury and neonatal alloimmune neutropenia. By deep sequencing the CD177 locus, we catalogued CD177 single nucleotide variants and identified a novel stop codon in CD177null individuals arising from a single base substitution in exon 7. This is not a mutation in CD177 itself, rather the CD177null phenotype arises when exon 7 of CD177 is supplied entirely by the CD177 pseudogene (CD177P1, which appears to have resulted from allelic gene conversion. In CD177 expressing individuals the CD177 locus contains both CD177P1 and CD177 sequences. The proportion of CD177hi neutrophils in the blood is a heritable trait. Abundance of CD177hi neutrophils correlates with homozygosity for CD177 reference allele, while heterozygosity for ectopic CD177P1 gene conversion correlates with increased CD177neg neutrophils, in which both CD177P1 partially incorporated allele and paired intact CD177 allele are transcribed. Human neutrophil heterogeneity for CD177 expression arises by ectopic allelic conversion. Resolution of the genetic basis of CD177null phenotype identifies a method for screening for individuals at risk of CD177 isoimmunisation.

Adding-point strategy for reduced-order hypersonic aerothermodynamics modeling based on fuzzy clustering

Science.gov (United States)

Chen, Xin; Liu, Li; Zhou, Sida; Yue, Zhenjiang

2016-09-01

Reduced order models(ROMs) based on the snapshots on the CFD high-fidelity simulations have been paid great attention recently due to their capability of capturing the features of the complex geometries and flow configurations. To improve the efficiency and precision of the ROMs, it is indispensable to add extra sampling points to the initial snapshots, since the number of sampling points to achieve an adequately accurate ROM is generally unknown in prior, but a large number of initial sampling points reduces the parsimony of the ROMs. A fuzzy-clustering-based adding-point strategy is proposed and the fuzzy clustering acts an indicator of the region in which the precision of ROMs is relatively low. The proposed method is applied to construct the ROMs for the benchmark mathematical examples and a numerical example of hypersonic aerothermodynamics prediction for a typical control surface. The proposed method can achieve a 34.5% improvement on the efficiency than the estimated mean squared error prediction algorithm and shows same-level prediction accuracy.

Computer-Assisted CBT for Child Anxiety: The Coping Cat CD-ROM

Science.gov (United States)

Khanna, Muniya S.; Kendall, Philip C.

2008-01-01

Empirical data support the efficacy of cognitive-behavioral therapy (CBT) for child anxiety, but there is need and merit in the development and evaluation of cost-effective and transportable CBT approaches. Relatedly, a widely endorsed goal is the dissemination of evidence-based treatments from research clinics to community settings.…

[Digitalization, archival storage and use of image documentation in the GastroBase-II system].

Science.gov (United States)

Kocna, P

1997-05-14

"GastroBase-II" is a module of the clinical information system "KIS-ComSyD"; The main part is represented by structured data-text with an expert system including on-line image digitalization in gastroenterology (incl. endoscopic, X-ray and endosonography pictures). The hardware and software of the GastroBase are described as well as six-years experiences with application of digitalized image data. An integration of a picture into text, reports, slides for a lecture or an electronic atlas is documented with examples. Briefly are reported out experiences with graphic editors (PhotoStyler), text editor (WordPerfect) and slide preparation for lecturing with the presentation software PowerPoint. The multimedia applications on the CD-ROM illustrate a modern trend using digitalized image documentation for pregradual and postgradual education.

Teaching Literature Using Multimedia. Final Report: Fund for the Improvement of Postsecondary Education.

Science.gov (United States)

Stalker, Sandra

"Journey Home," an interactive CD-ROM program about Homer's "Odyssey," was produced at North Shore Community College (Massachusetts) to create an innovative method for teaching literature. Based on a prototype developed on an Apple II, the program incorporates video, text, graphics, music, and artwork related to the Odyssey and…

A one-step selective fluorescence turn-on detection of cysteine and homocysteine based on a facile CdTe/CdS quantum dots–phenanthroline system

Energy Technology Data Exchange (ETDEWEB)

Chen, Sheng; Tian, Jianniao, E-mail: tianjn58@yahoo.com.cn; Jiang, Yixuan; Zhao, Yanchun; Zhang, Juanni; Zhao, Shulin

2013-07-17

Graphical abstract: A simple, selective, sensitive and low-cost turn-on photoluminescent sensor for cysteine and homocysteine based on the fluorescence recovery of the CdTe/CdS quantum dots (QDs)–phenanthroline (Phen) system was developed. -- Highlights: •A new label-free approach for determination of cysteine and homocysteine was developed. •The fluorescence turn-on method has sensitivity, high selectivity, low-cost and easy operation. •The method could be applied in rapid semiquantitative determination by digital visualization. -- Abstract: In this paper, we report a simple, selective, sensitive and low-cost turn-on photoluminescent sensor for cysteine and homocysteine based on the fluorescence recovery of the CdTe/CdS quantum dots (QDs)–phenanthroline (Phen) system. In the presence of Phen, the fluorescence of QDs could be quenched effectively due to the formation of the non-fluorescent complexes between water-soluble thioglycolic acid (TGA)-capped QDs and Phen. Subsequently, upon addition of cysteine and homocysteine, the strong affinity of cysteine and homocysteine to QDs enables Phen to be dissociated from the surface of QDs and to form stable and luminescent complexes with cysteine and homocysteine in solution. Thus, the fluorescence of CdTe/CdS QDs was recovered gradually. A good linear relationship was obtained from 1.0 to 70.0 μM for cysteine and from 1.0 to 90.0 μM for homocysteine, respectively. The detection limits of cysteine and homocysteine were 0.78 and 0.67 μM, respectively. In addition, the method exhibited a high selectivity for cysteine and homocysteine over the other substances, such as amino acids, thiols, proteins, carbohydrates, etc. More importantly, the sensing system can not only achieve quantitative detection of cysteine and homocysteine but also could be applied in semiquantitative cysteine and homocysteine determination by digital visualization. Therefore, as a proof-of-concept, the proposed method has potential

A one-step selective fluorescence turn-on detection of cysteine and homocysteine based on a facile CdTe/CdS quantum dots–phenanthroline system

International Nuclear Information System (INIS)

Chen, Sheng; Tian, Jianniao; Jiang, Yixuan; Zhao, Yanchun; Zhang, Juanni; Zhao, Shulin

2013-01-01

Graphical abstract: A simple, selective, sensitive and low-cost turn-on photoluminescent sensor for cysteine and homocysteine based on the fluorescence recovery of the CdTe/CdS quantum dots (QDs)–phenanthroline (Phen) system was developed. -- Highlights: •A new label-free approach for determination of cysteine and homocysteine was developed. •The fluorescence turn-on method has sensitivity, high selectivity, low-cost and easy operation. •The method could be applied in rapid semiquantitative determination by digital visualization. -- Abstract: In this paper, we report a simple, selective, sensitive and low-cost turn-on photoluminescent sensor for cysteine and homocysteine based on the fluorescence recovery of the CdTe/CdS quantum dots (QDs)–phenanthroline (Phen) system. In the presence of Phen, the fluorescence of QDs could be quenched effectively due to the formation of the non-fluorescent complexes between water-soluble thioglycolic acid (TGA)-capped QDs and Phen. Subsequently, upon addition of cysteine and homocysteine, the strong affinity of cysteine and homocysteine to QDs enables Phen to be dissociated from the surface of QDs and to form stable and luminescent complexes with cysteine and homocysteine in solution. Thus, the fluorescence of CdTe/CdS QDs was recovered gradually. A good linear relationship was obtained from 1.0 to 70.0 μM for cysteine and from 1.0 to 90.0 μM for homocysteine, respectively. The detection limits of cysteine and homocysteine were 0.78 and 0.67 μM, respectively. In addition, the method exhibited a high selectivity for cysteine and homocysteine over the other substances, such as amino acids, thiols, proteins, carbohydrates, etc. More importantly, the sensing system can not only achieve quantitative detection of cysteine and homocysteine but also could be applied in semiquantitative cysteine and homocysteine determination by digital visualization. Therefore, as a proof-of-concept, the proposed method has potential

Submesoscale Flows and Mixing in the Oceanic Surface Layer Using the Regional Oceanic Modeling System (ROMS)

Science.gov (United States)

2014-09-30

IMPACT/APPLICATIONS Geochemistry and Ecosystems: An important community use for ROMS is biogeochemisty: chemical cycles, water quality, blooms ...published, refereed] Colas, F., J.C. McWilliams, X. Capet, and J. Kurian, 2012: Heat balance and eddies in the Peru- Chile Current System. Climate

Empowering African scientists - an investigation into a CD-based installer for scubuntu

CSIR Research Space (South Africa)

Van Zyl, P

2008-11-01

Full Text Available . The refinement of these profiles and package collections is an ongoing activity that will be driven by the scubuntu user community. Investigative work was undertaken to determine the suitability of a CD-based installation program for scubuntu. An experimental...

CD4+ T cell effects on CD8+ T cell location defined using bioluminescence.

Directory of Open Access Journals (Sweden)

Mitra Azadniv

2011-01-01

Full Text Available T lymphocytes of the CD8+ class are critical in delivering cytotoxic function and in controlling viral and intracellular infections. These cells are "helped" by T lymphocytes of the CD4+ class, which facilitate their activation, clonal expansion, full differentiation and the persistence of memory. In this study we investigated the impact of CD4+ T cells on the location of CD8+ T cells, using antibody-mediated CD4+ T cell depletion and imaging the antigen-driven redistribution of bioluminescent CD8+ T cells in living mice. We documented that CD4+ T cells influence the biodistribution of CD8+ T cells, favoring their localization to abdominal lymph nodes. Flow cytometric analysis revealed that this was associated with an increase in the expression of specific integrins. The presence of CD4+ T cells at the time of initial CD8+ T cell activation also influences their biodistribution in the memory phase. Based on these results, we propose the model that one of the functions of CD4+ T cell "help" is to program the homing potential of CD8+ T cells.

T-x-y diagrams for reciprocal systems PbX + CdI2 = CdX + PbI2 (X=S, Se, Te)

International Nuclear Information System (INIS)

Odin, I.N.

2001-01-01

The present research is undertaken in search of the new complex phases with interesting physical properties. The synthesized samples was analyzed by differential thermal, X-ray diffraction and microstructural methods. The diagonal cross-section CdTe - PbI 2 of the mutual PbTe + CdI 2 = CdTe + PbI 2 system is stable. The T-x phase diagram of the CdTe - PbI 2 system possess eutectic type, the coordinates of eutectic point is 657 ± 2 K, 15 ± 1 mol. % of CdTe. The lead iodide based solid solutions with the mixed structure and the CdTe based solid solutions take place in the equilibria. Solid CdTe dissolves 0.2 mol. % PbI 2 . The fields of the primary crystallization of the CdTe, Pb 1-x Cd x I 2 , PbTe based solid solutions are on the liquidus surface [ru

CdTe QDs-based prostate-specific antigen probe for human prostate cancer cell imaging

International Nuclear Information System (INIS)

Dong Wei; Guo Li; Wang Meng; Xu Shukun

2009-01-01

L-glutathione (GSH) stabilized CdTe quantum dots (QDs) were directly prepared in aqueous solution. The as-prepared QDs were linked to prostate-specific antigen (PSA) for the direct labeling and linked to immunoglobulin G (IgG) for the indirect labeling of fixed prostate cancer cells. The results indicated that QD-based probes were ideal fluorescent markers with excellent spectral properties and photostability and much better than organic dyes making them very suitable in target detection. Meanwhile, the indirect labeling showed much better specificity than the direct labeling. Furthermore, the prepared CdTe QDs did not show detectable effect on cell growth after having cultured for three days, which suggested that the L-glutathione capped CdTe had scarcely cytotoxicity.

Electronic publishing of SPE papers

International Nuclear Information System (INIS)

Perdue, J.M.

1992-01-01

This paper reports that the SPE is creating an electronic index to over 25,000 technical papers and will produce a CD-ROM as an initial product. This SPE CD-ROM Masterdisc will be available at the SPE Annual Meeting in Washington, D.C. on October 4-7, 1992. The SPE Board has appointed an Ad Hoc Committee on Electronic Publishing to coordinate and oversee this project and to recommend authoring standards for submitting SPE papers electronically in the future

CdTe and CdSe quantum dots: synthesis, characterizations and applications in agriculture

International Nuclear Information System (INIS)

Ung, Thi Dieu Thuy; Tran, Thi Kim Chi; Pham, Thu Nga; Nguyen, Quang Liem; Nguyen, Duc Nghia; Dinh, Duy Khang

2012-01-01

This paper highlights the results of the whole work including the synthesis of highly luminescent quantum dots (QDs), characterizations and testing applications of them in different kinds of sensors. Concretely, it presents: (i) the successful synthesis of colloidal CdTe and CdSe QDs, their core/shell structures with single- and/or double-shell made by CdS, ZnS or ZnSe/ZnS; (ii) morphology, structural and optical characterizations of the synthesized QDs; and (iii) testing examples of QDs as the fluorescence labels for agricultural-bio-medical objects (for tracing residual pesticide in agricultural products, residual clenbuterol in meat/milk and for detection of H5N1 avian influenza virus in breeding farms). Overall, the results show that the synthesized QDs have very good crystallinity, spherical shape and strongly emit at the desired wavelengths between ∼500 and 700 nm with the luminescence quantum yield (LQY) of 30–85%. These synthesized QDs were used in fabrication of the three testing fluorescence QD-based sensors for the detection of residual pesticides, clenbuterol and H5N1 avian influenza virus. The specific detection of parathion methyl (PM) pesticide at a content as low as 0.05 ppm has been realized with the biosensors made from CdTe/CdS and CdSe/ZnSe/ZnS QDs and the acetylcholinesterase (AChE) enzymes. Fluorescence resonance energy transfer (FRET)-based nanosensors using CdTe/CdS QDs conjugated with 2-amino-8-naphthol-6-sulfonic acid were fabricated that enable detection of diazotized clenbuterol at a content as low as 10 pg ml −1 . For detection of H5N1 avian influenza virus, fluorescence biosensors using CdTe/CdS QDs bound on the surface of chromatophores extracted and purified from bacteria Rhodospirillum rubrum were prepared and characterized. The specific detection of H5N1 avian influenza virus in the range of 3–50 ng μl −1 with a detection limit of 3 ng μL −1 has been performed based on the antibody-antigen recognition. (review)

Delicacy, Imprecision, and Uncertainty of Oceanic Simulations: An Investigation with the Regional Oceanic Modeling System (ROMS)

Science.gov (United States)

2013-09-30

Geochemistry and Ecosystems: An important community use for ROMS is biogeochemisty: chemical cycles, water quality, blooms , micro-nutrients, larval...Sci., submitted. Colas, F., J.C. McWilliams, X. Capet, and J. Kurian, 2012: Heat balance and eddies in the Peru- Chile Current System. Climate

All-integrated and highly sensitive paper based device with sample treatment platform for Cd2+ immunodetection in drinking/tap waters.

Science.gov (United States)

López Marzo, Adaris M; Pons, Josefina; Blake, Diane A; Merkoçi, Arben

2013-04-02

Nowadays, the development of systems, devices, or methods that integrate several process steps into one multifunctional step for clinical, environmental, or industrial purposes constitutes a challenge for many ongoing research projects. Here, we present a new integrated paper based cadmium (Cd(2+)) immunosensing system in lateral flow format, which integrates the sample treatment process with the analyte detection process. The principle of Cd(2+) detection is based on competitive reaction between the cadmium-ethylenediaminetetraacetic acid-bovine serum albumin-gold nanoparticles (Cd-EDTA-BSA-AuNP) conjugate deposited on the conjugation pad strip and the Cd-EDTA complex formed in the analysis sample for the same binding sites of the 2A81G5 monoclonal antibody (mAb), specific to Cd-EDTA but not Cd(2+) free, which is immobilized onto the test line. This platform operates without any sample pretreatment step for Cd(2+) detection thanks to an extra conjugation pad that ensures Cd(2+) complexation with EDTA and interference masking through ovalbumin (OVA). The detection and quantification limits found for the device were 0.1 and 0.4 ppb, respectively, these being the lowest limits reported up to now for metal sensors based on paper. The accuracy of the device was evaluated by addition of known quantities of Cd(2+) to different drinking water samples and subsequent Cd(2+) content analysis. Sample recoveries ranged from 95 to 105% and the coefficient of variation for the intermediate precision assay was less than 10%. In addition, the results obtained here were compared with those obtained with the well-established inductively coupled plasma emission spectroscopy (ICPES) and the analysis of certificate standard samples.

Evolución de las bases de datos jurídicas en España

Directory of Open Access Journals (Sweden)

María Luisa Alvite Díez

2004-01-01

Full Text Available Se presenta el camino recorrido en el desarrollo de las bases de datos jurídicas en España, un sector de indudable relevancia en el mercado de la información. Desde los primeros intentos de finales de los años sesenta del pasado siglo por aplicar proyectos de automatización en el tratamiento de la documentación jurídica, pasando por las escasas tentativas de bases de datos en línea, hasta el desarrollo espectacular del CD-ROM a partir del año 1991. Se revisa la consolidación del mercado en formato óptico y la adaptación de la industria al entorno web. Se tratan, por último, aspectos relacionados con la globalización y la protección jurídica de estas bases de datos.

Different thresholds of T cell activation regulate FIV infection of CD4+CD25+ and CD4+CD25- cells

International Nuclear Information System (INIS)

Joshi, Anjali; Garg, Himanshu; Tompkins, Mary B.; Tompkins, Wayne A.

2005-01-01

Cellular activation plays an important role in retroviral replication. Previously, we have shown that CD4 + CD25 + T cells by the virtue of their partially activated phenotype represent ideal candidates for a productive feline immunodeficiency virus (FIV) infection. In the present study, we extended our previous observations with regard to FIV replication in CD4 + CD25 + and CD4 + CD25 - cells under different stimulation conditions. Both CD4 + CD25 + and CD4 + CD25 - cells remain latently infected in the absence of IL-2 or concanvalinA (ConA), respectively; harboring a replication competent provirus capable of reactivation several days post-infection. While CD4 + CD25 + cells require low levels of exogenous IL-2 and virus inputs for an efficient FIV replication, CD4 + CD25 - T cells can only be productively infected in the presence of either high concentrations of IL-2 or high virus titers, even in the absence of mitogenic stimulation. Interestingly, while high virus input activates CD4 + CD25 - cells to replicate FIV, it induces apoptosis in a high percentage of CD4 + CD25 + T cells. High IL-2 concentrations but not high virus inputs lead to surface upregulation of CD25 and significant cellular proliferation in CD4 + CD25 - cells. These results suggest that CD4 + CD25 + and CD4 + CD25 - T cells have different activation requirements which can be modulated by both viral and cytokine stimuli to reach threshold activation levels in order to harbor a productive FIV infection. This holds implications in vivo for CD4 + CD25 + and CD4 + CD25 - cells to serve as potential reservoirs of a productive and latent FIV infection

Effect of Ankle Range of Motion (ROM) and Lower-Extremity Muscle Strength on Static Balance Control Ability in Young Adults: A Regression Analysis

Science.gov (United States)

Kim, Seong-Gil

2018-01-01

Background The purpose of this study was to investigate the effect of ankle ROM and lower-extremity muscle strength on static balance control ability in young adults. Material/Methods This study was conducted with 65 young adults, but 10 young adults dropped out during the measurement, so 55 young adults (male: 19, female: 36) completed the study. Postural sway (length and velocity) was measured with eyes open and closed, and ankle ROM (AROM and PROM of dorsiflexion and plantarflexion) and lower-extremity muscle strength (flexor and extensor of hip, knee, and ankle joint) were measured. Pearson correlation coefficient was used to examine the correlation between variables and static balance ability. Simple linear regression analysis and multiple linear regression analysis were used to examine the effect of variables on static balance ability. Results In correlation analysis, plantarflexion ROM (AROM and PROM) and lower-extremity muscle strength (except hip extensor) were significantly correlated with postural sway (pregression analysis, plantar flexion PROM with eyes open significantly influenced sway length (B=0.681) and sway velocity (B=0.011). Conclusions Lower-extremity muscle strength and ankle plantarflexion ROM influenced static balance control ability, with ankle plantarflexion PROM showing the greatest influence. Therefore, both contractile structures and non-contractile structures should be of interest when considering static balance control ability improvement. PMID:29760375

Are you dyslexic?

CERN Multimedia

2003-01-01

If so, read this article. You may be able to help children with the same disability as you. The BBC and the charity Dyslexia International Tools and Technologies (DITT) are currently producing a CD-ROM for dyslexic children aged 9 to 14. One of the aims is to offer them encouragement by showing them that people with dyslexia have made successes of their lives. The BBC is therefore looking for people from all over Europe who have succeeded despite their condition. The CD-ROM will be translated into several different languages and distributed throughout Europe. If you are a high-level physicist with dyslexia, you could take part in the making of this CD-Rom. The BBC will be coming to film 10-minute interviews about people's experience with dyslexia and the advice they can offer to young people suffering from the same condition. Please send an e-mail to James.Gillies@cern.ch as soon as possible.

EOSDIS Terra Data Sampler #1: Western US Wildfires 2000. 1.1

Science.gov (United States)

Perkins, Dorothy C. (Technical Monitor)

2000-01-01

This CD-ROM contains sample data in HDF-EOS format from the instruments on board the Earth Observing System (EOS) Terra satellite: (1) Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER); (2) Clouds and the Earth's Radiant Energy System (CERES); (3) Multi-angle Imaging Spectroradiometer (MISR); and (4) Moderate Resolution Imaging Spectroradiometer (MODIS). Data from the Measurements of Pollution in the Troposphere (MOPITT) instrument were not available for distribution (as of October 17, 2000). The remotely sensed, coincident data for the Western US wildfires were acquired August 30, 2000. This CD-ROM provides information about the Terra mission, instruments, data, and viewing tools. It also provides the Collage tool for viewing data, and links to Web sites containing other digital data processing software. Full granules of the data on this CD-ROM and other EOS Data and Information System (EOSDIS) data products are available from the NASA Distributed Active Archive Centers (DAACs).

CdS/CdSe quantum dot shell decorated vertical ZnO nanowire arrays by spin-coating-based SILAR for photoelectrochemical cells and quantum-dot-sensitized solar cells.

Science.gov (United States)

Zhang, Ran; Luo, Qiu-Ping; Chen, Hong-Yan; Yu, Xiao-Yun; Kuang, Dai-Bin; Su, Cheng-Yong

2012-04-23

A CdS/CdSe composite shell is assembled onto the surface of ZnO nanowire arrays with a simple spin-coating-based successive ionic layer adsorption and reaction method. The as-prepared photoelectrode exhibit a high photocurrent density in photoelectrochemical cells and also generates good power conversion efficiency in quantum-dot-sensitized solar cells. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Single crystalline multi-petal Cd nanoleaves prepared by thermal reduction of CdO

International Nuclear Information System (INIS)

Khan, Waheed S.; Cao, Chuanbao; Aslam, Imran; Ali, Zulfiqar; Butt, Faheem K.; Mahmood, Tariq; Nabi, Ghulam; Ihsan, Ayesha; Usman, Zahid; Rehman, Asma

2013-01-01

Highlights: ► Cd nanoleaves are obtained on abraded Cu substrate by thermal reduction of CdO. ► Vapour solid (VS) growth mechanism governs the formation of Cd nanoleaves (CdNLs). ► PL spectrum for CdNLs exhibits a strong ultraviolet (UV) emission band at 353 nm. ► UV band is attributed to interband radiative recombination under Xe illumination. -- Abstract: Multi-petal cadmium metal nanoleaves with 30–40 nm thickness were fabricated on abraded copper substrate by simple thermal reduction of cadmium oxide (CdO) powder at 1050 °C inside horizontal tube furnace (HTF) under nitrogen gas flow. The structural, compositional and morphological characterizations of the as-prepared cadmium nanoleaves (CdNLs) were performed by X-ray diffraction, energy dispersive X-ray spectroscopy, scanning electron microscopy, high resolution transmission electron microscopy and selected area electron diffraction. Non-catalytic vapour–solid (VS) process based growth mechanism governing the formation of CdNLs has been proposed and discussed briefly. Photoluminescence (PL) spectrum for CdNLs measured at room temperature exhibited a single prominent emission band at 353 nm which may either be ascribed to surface oxidation effects or interband radiative recombination under Xe light illumination.

Single crystalline multi-petal Cd nanoleaves prepared by thermal reduction of CdO

Energy Technology Data Exchange (ETDEWEB)

Khan, Waheed S. [Research Centre of Materials Science, School of Materials Science and Engineering, Beijing Institute of Technology, Beijing 100081 (China); National Institute for Biotechnology and Genetic Engineering (NIBGE), P.O. Box No. 577, Jhang Road, Faisalabad (Pakistan); Cao, Chuanbao, E-mail: cbcao@bit.edu.cn [Research Centre of Materials Science, School of Materials Science and Engineering, Beijing Institute of Technology, Beijing 100081 (China); Aslam, Imran; Ali, Zulfiqar; Butt, Faheem K.; Mahmood, Tariq; Nabi, Ghulam [Research Centre of Materials Science, School of Materials Science and Engineering, Beijing Institute of Technology, Beijing 100081 (China); Ihsan, Ayesha [National Institute for Biotechnology and Genetic Engineering (NIBGE), P.O. Box No. 577, Jhang Road, Faisalabad (Pakistan); Usman, Zahid [Research Centre of Materials Science, School of Materials Science and Engineering, Beijing Institute of Technology, Beijing 100081 (China); Rehman, Asma [National Institute for Biotechnology and Genetic Engineering (NIBGE), P.O. Box No. 577, Jhang Road, Faisalabad (Pakistan)

2013-02-15

Highlights: ► Cd nanoleaves are obtained on abraded Cu substrate by thermal reduction of CdO. ► Vapour solid (VS) growth mechanism governs the formation of Cd nanoleaves (CdNLs). ► PL spectrum for CdNLs exhibits a strong ultraviolet (UV) emission band at 353 nm. ► UV band is attributed to interband radiative recombination under Xe illumination. -- Abstract: Multi-petal cadmium metal nanoleaves with 30–40 nm thickness were fabricated on abraded copper substrate by simple thermal reduction of cadmium oxide (CdO) powder at 1050 °C inside horizontal tube furnace (HTF) under nitrogen gas flow. The structural, compositional and morphological characterizations of the as-prepared cadmium nanoleaves (CdNLs) were performed by X-ray diffraction, energy dispersive X-ray spectroscopy, scanning electron microscopy, high resolution transmission electron microscopy and selected area electron diffraction. Non-catalytic vapour–solid (VS) process based growth mechanism governing the formation of CdNLs has been proposed and discussed briefly. Photoluminescence (PL) spectrum for CdNLs measured at room temperature exhibited a single prominent emission band at 353 nm which may either be ascribed to surface oxidation effects or interband radiative recombination under Xe light illumination.

Mi-spillet

DEFF Research Database (Denmark)

Larsen, Lea Lund; Hejlesen, Stine

2003-01-01

MI-spillet er et undervisningsspil til folkeskolens mellemtrin og udskolingen. Spillet omformer Howard Gardners teori om de mange intelligenser til et praktisk og håndgribeligt værktøj til brug i folkeskolen. Spillet indeholder et undervisningsmateriale bestående af lærervejledning og kopimappe...... emnebaseret eller tværfagligt arbejde. Alt materialet ligger samlet på en cd-rom, hvorfra materialet printes. Skolen kan derfor ved køb af én cd-rom printe og producere et ubegrænset antal spil. Cd-rommen indeholder: 1. Lærervejledning 2. MI-spillet * Gulvpladerne * Spørgsmål til spillet * Bilag til...

Snapshots: Marimba Magic; Rediscovering Coyote and Raven; New Life for an Old War; Good Health, Good Heart; Winds of Change; What the Forest Gives; Lessons in the Loop; a Talking Book.

Science.gov (United States)

Reed, Bracken; Linik, Joyce Riha; Muir, Maya; Fisher, Amy

2002-01-01

Applications of project-based learning are illustrated by examples of projects involving music, art, history, a partnership with a hospital, Native American plant remedies, roller coaster design, and making a "talking book" (CD-ROM) in English and Lushootseed (language of the Tulalip Tribes). Project learning can meet standards while involving…

Gender-Specific HIV Prevention with Urban Early-Adolescent Girls: Outcomes of the Keepin' It Safe Program

Science.gov (United States)

Di Noia, Jennifer; Schinke, Steven P.

2007-01-01

This study evaluates the efficacy of Keepin' It Safe, a theory-based, gender-specific, CD-ROM-mediated HIV prevention program for urban, early adolescent girls. Intervention effects were examined in a randomized, pretest-posttest wait-list control-group design. Changes in HIV/AIDS knowledge, protective attitudes, and skills for reducing HIV…

Quantum dot sensitized solar cell based on TiO2/CdS/Ag2S heterostructure

Science.gov (United States)

Pawar, Sachin A.; Patil, Dipali S.; Kim, Jin Hyeok; Patil, Pramod S.; Shin, Jae Cheol

2017-04-01

Quantum dot sensitized solar cell (QDSSC) is fabricated based on a stepwise band structure of TiO2/CdS/Ag2S to improve the photoconversion efficiency of TiO2/CdS system by incorporating a low band gap Ag2S QDs. Vertically aligned TiO2 nanorods assembly is prepared by a simple hydrothermal technique. The formation of CdS and Ag2S QDs over TiO2 nanorods assembly as a photoanode is carried out by successive ionic layer adsorption and reaction (SILAR) technique. The synthesized electrode materials are characterized by XRD, XPS, field emission scanning electron microscopy (FE-SEM), Optical, solar cell and electrochemical performances. The results designate that the QDs of CdS and Ag2S have efficiently covered exterior surfaces of TiO2 nanorods assembly. A cautious evaluation between TiO2/CdS and TiO2/CdS/Ag2S sensitized cells tells that CdS and Ag2S synergetically helps to enhance the light harvesting ability. Under AM 1.5G illumination, the photoanodes show an improved power conversion efficiency of 1.87%, in an aqueous polysulfide electrolyte with short-circuit photocurrent density of 7.03 mA cm-2 which is four fold higher than that of a TiO2/CdS system.

Development and prospects of CdS/CdTe solar cell

International Nuclear Information System (INIS)

Vaillant, L.

2008-01-01

Based on the n-CdS/p-CdTe heterojunction solar cell to thin films, both polycrystalline materials, started to be studied at beginning of the 1970s. However, since the 1960s were structures in which the active material was CdTe. Since then, in almost all proposed cell designs, the main problems encountered related to two important points: recombination losses associated with the main interface and the difficulty to obtain a low resistance ohmic contact with the p-CdTe. For decades, the efficiency of the cell was to rise as I studied and perfected the same from a macroscopic view of the device. Slowly they proposed, manufactured and studied structures responding with higher conversion efficiency. However, in recent years emphasis has been on the need to understand the microscopic mechanisms responsible for the transformations that occur in the device during the manufacturing process of the same. This fact has caused a deepening in the study of polycrystalline nature of the materials making up the cell, using techniques for solving micro and Nano. Special attention have been the borders of grain in the CdTe and studies related to the main junction between CdTe and CdS. This article will attempt to reflect an analysis of the evolution in the design of this type of cell, from its beginnings up to our times.

Elevated Temperature Photophysical Properties and Morphological Stability of CdSe and CdSe/CdS Nanoplatelets

Energy Technology Data Exchange (ETDEWEB)

Rowland, Clare E. [Department; Center; Fedin, Igor [Department; Diroll, Benjamin T. [Center; Liu, Yuzi [Center; Talapin, Dmitri V. [Center; Department; Schaller, Richard D. [Department; Center

2018-01-03

Elevated temperature optoelectronic performance of semiconductor nanomaterials remains an important issue for applications. Here we examine two-dimensional CdSe nanoplatelets (NPs) and CdS/CdSe/CdS shell/core/shell sandwich NPs at temperatures ranging from 300-700 K using static and transient spectroscopies as well as in-situ transmission electron microscopy. NPs exhibit reversible changes in PL intensity, spectral position, and emission linewidth with temperature elevation up to ~500 K, losing a factor of ~8 to 10 in PL intensity at 400 K relative to ambient. Temperature elevation above ~500 K yields thickness dependent, irreversible degradation in optical properties. Electron microscopy relates stability of the NP morphology up to near 600 K followed by sintering and evaporation at still higher temperatures. The mechanism of reversible PL loss, based on differences in decay dynamics between time-resolved photoluminescence and transient absorption, arise primarily from hole trapping in both NPs and sandwich NPs.

Total hip arthroplasty (S-ROM stem and subtrochanteric osteotomy for Crowe type IV developmental dysplasia of the hip

Directory of Open Access Journals (Sweden)

Liangtao Li

2016-01-01

Conclusions: In the primary THA for the treatment of irreducible DDH, subtrochanteric oblique osteotomy combined with the freely-rotatable S-ROM stem provided favorable short term outcomes by affording both morphological and functional advantages.

High-Efficiency Photochemical Water Splitting of CdZnS/CdZnSe Nanostructures

Directory of Open Access Journals (Sweden)

Chen-I Wang

2013-01-01

Full Text Available We have prepared and employed TiO2/CdZnS/CdZnSe electrodes for photochemical water splitting. The TiO2/CdZnS/CdZnSe electrodes consisting of sheet-like CdZnS/CdZnSe nanostructures (8–10 μm in length and 5–8 nm in width were prepared through chemical bath deposition on TiO2 substrates. The TiO2/CdZnS/CdZnSe electrodes have light absorption over the wavelength 400–700 nm and a band gap of 1.87 eV. Upon one sun illumination of 100 mW cm−2, the TiO2/CdZnS/CdZnSe electrodes provide a significant photocurrent density of 9.7 mA cm−2 at −0.9 V versus a saturated calomel electrode (SCE. Incident photon-to-current conversion efficiency (IPCE spectrum of the electrodes displays a maximum IPCE value of 80% at 500 nm. Moreover, the TiO2/CdZnS/CdZnSe electrodes prepared from three different batches provide a remarkable photon-to-hydrogen efficiency of 7.3 ± 0.1% (the rate of the photocatalytically produced H2 by water splitting is about 172.8 mmol·h−1·g−1, which is the most efficient quantum-dots-based photocatalysts used in solar water splitting.

IAEA eLearning Program: The Use of Radiation Detection Instruments

International Nuclear Information System (INIS)

2010-01-01

This CD-ROM contains a computer based training on Radiation Detection Techniques for Nuclear Security Applications. The IAEA Nuclear Security eLearning tool offers computer based training to Frontline Officers to improve their understanding about key elements of the use of radiation detection instruments. The eLearning program prepares Frontline Officers for the IAEA Detection and Response Frontline Officer course

Flexible pressure sensor based on graphene aerogel microstructures functionalized with CdS nanocrystalline thin film

Science.gov (United States)

Plesco, Irina; Dragoman, Mircea; Strobel, Julian; Ghimpu, Lidia; Schütt, Fabian; Dinescu, Adrian; Ursaki, Veaceslav; Kienle, Lorenz; Adelung, Rainer; Tiginyanu, Ion

2018-05-01

In this paper, we report on functionalization of graphene aerogel with a CdS thin film deposited by magnetron sputtering and on the development of flexible pressure sensors based on ultra-lightweight CdS-aerogel nanocomposite. Analysis by scanning electron microscopy, transmission electron microscopy and energy dispersive X-ray analysis disclose the uniform deposition of nanocrystalline CdS films with quasi-stoichiometric composition. The piezoresistive response of the aforementioned nanocomposite in the pressure range from 1 to 5 atm is found to be more than one order of magnitude higher than that inherent to suspended graphene membranes, leading to an average sensitivity as high as 3.2 × 10-4 kPa-1.

The development of drift-strip detectors based on CdZnTe

DEFF Research Database (Denmark)

Gostilo, V.; Budtz-Jørgensen, Carl; Kuvvetli, Irfan

2002-01-01

The design and technological development of a CdZnTe drift strip detector is described. The device is based on a monocrystal of dimensions 10 x 10 x 3 mm(3) and has a pitch of 200 mum and a strip width of 100 mum. The strip length is 9.5 mm. The distribution of the leakage currents of the strips...

Reprocessing of multi-channel seismic-reflection data collected in the Chukchi Sea

Science.gov (United States)

Agena, W.F.; Lee, M.W.; Hart, P.E.

2001-01-01

Contained on this set of two CD-ROMs are stacked and migrated multi-channel seismic-reflection data for 44 lines recorded in the Chukchi Sea, northern Alaska, by the United States Geological Survey in 1977, 1978, and 1980. All data were reprocessed by the USGS in 2000 using updated methods. The resulting final data have both increased temporal and spatial resolution thus providing improved interpretability. An added benefit of these CD-ROMs is that they are a more stable, long-term archival medium for the data.

Determination of normal expression patterns of CD86, CD210a, CD261, CD262, CD264, CD358, and CD361 in peripheral blood and bone marrow cells by flow cytometry.

Science.gov (United States)

Rudolf-Oliveira, Renata Cristina Messores; Auat, Mariangeles; Cardoso, Chandra Chiappin; Santos-Pirath, Iris Mattos; Lange, Barbara Gil; Pires-Silva, Jéssica; Moraes, Ana Carolina Rabello de; Dametto, Gisele Cristina; Pirolli, Mayara Marin; Colombo, Maria Daniela Holthausen Périco; Santos-Silva, Maria Claudia

2018-02-01

In 2010, new monoclonal antibodies were submitted to the 9th International Workshop on Human Leukocyte Differentiation Antigens, and there are few studies demonstrating normal expression patterns of these markers. Thus, the objective of this study was to determine the normal patterns of cell expression of CD86, CD210a, CD261, CD262, CD264, CD358, and CD361 in peripheral blood (PB) and bone marrow (BM) samples by flow cytometry. In the present study, CD86 was expressed only in monocytes and B lymphocytes in PB and in monocytes and plasma cells in BM. Regarding CD210a expression, in PB samples, monocytes and NK cells showed weak expression, while neutrophils, B and T lymphocytes, and basophils showed weak and partial expression. In BM samples, expression of CD210a was observed in eosinophils, monocytes, and B and T/NK lymphocytes. Weak expression of CD210a was also observed in neutrophilic cells and plasma cells. All B cell maturation stages had weak expression of CD210a except for immature B cells, which did not express this marker. In the present study, no cell type in PB samples showed positivity for CD261 and, in BM samples, there was very weak expression in neutrophilic series, monocytes, and B lymphocytes. Conversely, plasma cells showed positivity for CD261 with a homogeneous expression. For CD262, there was weak expression in monocytes, neutrophils, and B lymphocytes in PB samples and weak expression in monocytes, B lymphocytes, and plasma cells in BM samples. The evaluation of CD264 showed very weak expression in B cells in PB samples and no expression in BM cells. Very weak expression of CD358 was observed in neutrophils, monocytes, and B lymphocytes in PB and BM samples. In addition, in BM samples, plasma cells and T lymphocytes showed weak expression of CD358. In relation to the maturation stages of B cells, there was weak expression in pro-B cel, pre-B cell, and mature B cell. In the present study, it was possible to observe expression of CD361 in all

OLED-polypropylene bio-CD sensor

Science.gov (United States)

Vengasandra, Srikanth; Cai, Yuankun; Grewell, David; Shinar, Joseph; Shinar, Ruth

2008-08-01

With the goal of developing microfluidic platforms for sensing applications, flash-free micro patterns were embossed in polypropylene surfaces with ultrasonic heating for a biosensing lab-on-CD application. The embossed features were designed to act as reservoirs, valves, and reaction chambers to allow, in combination with a compact sensing platform, the monitoring of analyte levels using a standard PC-CD player. To generate the compact sensor, as an example, we chose the photoluminescence (PL)-based detection of lactate and glucose using an OLED-based sensing platform. Once embossed, the surface energy of the plastic substrate was chemically modified to make it hydrophilic. Reagents, placed in separate reservoirs, were directed through burst valves towards a reaction chamber via CD rotation. Lactate or glucose were monitored by measuring the effect of the related dissolved oxygen level on the PL decay time of an oxygen-sensitive dye, following analyte oxidation catalyzed by a suitable specific oxidase enzyme. The results demonstrate the potential of integrating OLEDs as excitation sources in PL-based sensors with microfluidic CD-based platforms, including for simultaneous multiple analyses.

CdSe white quantum dots-based white light-emitting diodes with high color rendering index

Science.gov (United States)

Su, Yu-Sheng; Hsiao, Chih-Chun; Chung, Shu-Ru

2016-09-01

A white light emission CdSe quantum dots (QDs) can be prepared by chemical route under 180°C. An organic oleic acid (OA) is used to react with CdO to form Cd-OA complex. Hexadecylamine (HDA) and 1-Octadecene (ODE) were used as co-surfactants. By controlling the reaction time, a white light emission CdSe QDs can be obtained after reacts for 3 to 10 min. The luminescence spectra compose two obvious emission peaks and entire visible light ranges from 400 to 650 nm. Based on TEM measurement result, spherical morphologies with particle size 2.39+/-0.27 nm can be obtained. The quantum yields (QYs) of white CdSe QD are between 20 and 60 %, which depends on reaction time. A white CdSe QDs were mixed with UV cured gel (OPAS-226) with weight ratios 50.0 wt. %, and putted the mixture into reflective cup (3020, 13 mil) as convert type. The white LEDs have controllable CIE coordinates and correlated color temperature (CCT). The luminous efficacy of the device is less than 3 lm/W, but the color rendering index (CRI) for all devices are higher than 80. Since the luminous efficacy of hybrid devices has a direct dependence on the external QY of the UV-LED as well, the luminous efficacy can be improved by well dispersion of CdSe QDs in UV gel matrix and using optimized LED chips. Therefore, in this study, we provide a new and simple method to prepare high QY of white CdSe QDs and its have a potential to applicate in solid-state lighting.

Usability Design Strategies for Children: Developing Children's Learning and Knowledge in Decreasing Their Dental Anxiety

Science.gov (United States)

Yahaya, Wan Ahmad Jaafar Wan; Salam, Sobihatun Nur Abdul

2010-01-01

This paper presents an example of how usability design strategies for children can be designed into educational material using CD-ROM based multimedia application for assisting parents and teachers to develop children's learning and knowledge in decreasing as well as motivate children aged 7-9 years old to reduce their anxious feelings towards…

Inventory of Innovative Learning Materials in Marine Science and Technology. UNESCO Reports in Marine Science 60.

Science.gov (United States)

Richards, Adrian F.; Richards, Efrosine A.

The Inventory of Innovative Learning Materials in Marine Science and Technology includes 32 computer-, 148 video-, 16 film-, and 11 CD-ROM-based entries. They concern materials in biosciences (67), chemistry (5), geosciences (16), physics (23), technology (76) and other (20). This first, initial compilations is conceived as the basis for more…

Providing Electronic Writing Resources for Academic Purposes: Issues of Control and Flexibility.

Science.gov (United States)

Bruce, Nigel

2001-01-01

Reviews "Academic Writing: An Interactive Language Based CD-ROM for Teaching Academic Writing Skills to University Students." Suggests language teachers in the tertiary sector are required to accommodate the specific disciplinary needs of their students, and that it is rare for most commercial textbooks to find their way into an English for…

Hybrid nanocrystal/polymer solar cells based on tetrapod-shaped CdSexTe1-x nanocrystals

International Nuclear Information System (INIS)

Zhou Yi; Li Yunchao; Zhong Haizheng; Hou Jianhui; Ding Yuqin; Yang Chunhe; Li Yongfang

2006-01-01

A series of ternary tetrapodal nanocrystals of CdSe x Te 1-x with x = 0 (CdTe), 0.23, 0.53, 0.78, 1 (CdSe) were synthesized and used to fabricate hybrid nanocrystal/polymer solar cells. Herein, the nanocrystals acted as electron acceptors, and poly(2-methoxy-5-(2'-ethyl-hexyloxy)-1,4-phenylene vinylene) (MEH-PPV) was used as an electron donor. It was found that the open circuit voltage (V oc ), short-circuit current (J sc ) and power conversion efficiency (η) of the devices all increased with increasing Se content in the CdSe x Te 1-x nanocrystals under identical experimental conditions. The solar cell based on the blend of tetrapodal CdSe nanocrystals and MEH-PPV (9:1 w/w) showed the highest power conversion efficiency of 1.13% under AM 1.5, 80 mW cm -2 , and the maximum incident photon to converted current efficiency (IPCE) of the device reached 47% at 510 nm. The influence of nanocrystal composition on the photovoltaic properties of the hybrid solar cells was explained by the difference of the band level positions between MEH-PPV and the nanocrystals

Enumeration of antigen-specific CD8+ T lymphocytes by single-platform, HLA tetramer-based flow cytometry: a European multicenter evaluation.

Science.gov (United States)

Heijnen, Ingmar A F M; Barnett, David; Arroz, Maria J; Barry, Simon M; Bonneville, Marc; Brando, Bruno; D'hautcourt, Jean-Luc; Kern, Florian; Tötterman, Thomas H; Marijt, Erik W A; Bossy, David; Preijers, Frank W M B; Rothe, Gregor; Gratama, Jan W

2004-11-01

HLA class I peptide tetramers represent powerful diagnostic tools for detection and monitoring of antigen-specific CD8(+) T cells. The impetus for the current multicenter study is the critical need to standardize tetramer flow cytometry if it is to be implemented as a routine diagnostic assay. Hence, the European Working Group on Clinical Cell Analysis set out to develop and evaluate a single-platform tetramer-based method that used cytomegalovirus (CMV) as the antigenic model. Absolute numbers of CMV-specific CD8(+) T cells were obtained by combining the percentage of tetramer-binding cells with the absolute CD8(+) T-cell count. Six send-outs of stabilized blood from healthy individuals or CMV-carrying donors with CMV-specific CD8(+) T-cell counts of 3 to 10 cells/microl were distributed to 7 to 16 clinical sites. These sites were requested to enumerate CD8(+) T cells and, in the case of CMV-positive donors, CMV-specific subsets on three separate occasions using the standard method. Between-site coefficients of variation of less than 10% (absolute CD8(+) T-cell counts) and approximately 30% (percentage and absolute numbers of CMV-specific CD8(+) T cells) were achieved. Within-site coefficients of variation were approximately 5% (absolute CD8(+) T-cell counts), approximately 9% (percentage CMV-specific CD8(+) T cells), and approximately 17% (absolute CMV-specific CD8(+) T-cell counts). The degree of variation tended to correlate inversely with the proportion of CMV-specific CD8(+) T-cell subsets. The single-platform MHC tetramer-based method for antigen-specific CD8(+) T-cell counting has been evaluated by a European group of laboratories and can be considered a reproducible assay for routine enumeration of antigen-specific CD8(+) T cells. (c) 2004 Wiley-Liss, Inc.

Photovoltaic performance of a Cd{sub 1−x}Mg{sub x}Te/CdS top-cell structure

Energy Technology Data Exchange (ETDEWEB)

Martinez, Omar S. [Instituto de Energías Renovables, Universidad Nacional Autónoma de México, Temixco, Morelos 62580 (Mexico); Centro del Cambio Global y la Sustentabilidad en el Sureste, Villahermosa, Tabasco 86080 (Mexico); Regalado-Pérez, E.; Mathews, N.R. [Instituto de Energías Renovables, Universidad Nacional Autónoma de México, Temixco, Morelos 62580 (Mexico); Morales, Erik R. [División Académica de Ingeniería y Arquitectura, Universidad Juárez Autónoma de Tabasco, Cunduacán, Tabasco 86690 (Mexico); Reyes-Coronado, David [Unidad Académica Playa del Carmen, Universidad de Quintana Roo, Playa del Carmen, Quintana Roo 77710 (Mexico); Galvez, Geovanni Hernández [Centro del Cambio Global y la Sustentabilidad en el Sureste, Villahermosa, Tabasco 86080 (Mexico); Mathew, Xavier, E-mail: xm@ier.unam.mx [Instituto de Energías Renovables, Universidad Nacional Autónoma de México, Temixco, Morelos 62580 (Mexico)

2015-05-01

In this paper we report the progress in developing a wide band gap alloy material based on CdTe to use as the top-cell absorber in tandem solar cells. High photovoltaic performance for a Cd{sub 1−x}Mg{sub x}Te/CdS top-cell was achieved by tuning the composition of the Cd{sub 1−x}Mg{sub x}Te film, and optimizing the device processing. We have carried out studies on the effect of vapor chloride treatment of the Cd{sub 1−x}Mg{sub x}Te/CdS device and the thermal annealing of the Cu/Au contacts on the opto-electronic properties of the device. With improved contact processing and post deposition treatments, we were able to achieve 9.3% efficiency for a 1.6 eV band gap top-cell; Cd{sub 1−x}Mg{sub x}Te/CdS on conductive glass substrate. - Highlights: • Cd{sub 1−x}Mg{sub x}Te films obtained by co-evaporation of CdTe and Mg • Band gap of Cd{sub 1−x}Mg{sub x}Te can be easily tuned by verifying x. • Band gap of Cd{sub 1−x}Mg{sub x}Te is stable only for short annealing durations. • Obtained efficiency of a Cd{sub 1−x}Mg{sub x}Te based device with a band gap of 1.6 eV is 9.3%.

Validation of Microcapillary Flow Cytometry for Community-Based CD4+ T Lymphocyte Enumeration in Remote Burkina Faso

Science.gov (United States)

Renault, Cybèle A; Traore, Arouna; Machekano, Rhoderick N; Israelski, Dennis M

2010-01-01

Background: CD4+ T lymphocyte enumeration plays a critical role in the initiation and monitoring of HIV-infected patients on antiretroviral therapy. There is an urgent need for low-cost CD4+ enumeration technologies, particularly for use in dry, dusty climates characteristic of many small cities in Sub-Saharan Africa. Design: Cross-sectional study. Methods: Blood samples from 98 HIV-infected patients followed in a community HIV clinic in Ouahigouya, Burkina Faso were obtained for routine CD4+ T lymphocyte count monitoring. The blood samples were divided into two aliquots, on which parallel CD4+ measurements were performed using microcapillary (Guava EasyCD4) and dedicated (Becton Dickinson FACSCount) CD4+ enumeration systems. Spearman rank correlation coefficient was calculated, and the sensitivity, specificity and positive predictive value (PPV) for EasyCD4 <200 cells/µL were determined compared to the reference standard FACSCount CD4 <200 cells/µL. Results: Mean CD4 counts for the EasyCD4 and FACSCount were 313.75 cells/µL and 303.47 cells/µL, respectively. The Spearman rank correlation coefficient was 0.92 (p<0.001). Median values using EasyCD4 were higher than those with the FACSCount (p=0.004). For a CD4<350 cells/uL, sensitivity of the EasyCD4 was 93.9% (95%CI 85.2-98.3%), specificity was 90.6% (95% CI 75.0-98.0%), and PPV was 95.4% (95%CI 87.1-99.0%). Conclusion: Use of the EasyCD4 system was feasible and highly accurate in the harsh conditions of this remote city in Sub-Saharan Africa, demonstrating acceptable sensitivity and specificity compared to a standard operating system. Microcapillary flow cytometry offers a cost-effective alternative for community-based, point-of-care CD4+ testing and could play a substantial role in scaling up HIV care in remote, resource-limited settings. PMID:21253463

A Cd(II)-based metal-organic framework as a luminance sensor to nitrobenzene and Tb(III) ion.

Science.gov (United States)

Qu, Xiang-Long; Gui, Di; Zheng, Xiao-Li; Li, Rui; Han, Hong-Liang; Li, Xia; Li, Pei-Zhou

2016-04-28

A Cd(II)-based metal-organic framework, [Cd2(DPDC)2(BTB)]∞ (Cd-MOF, DPDC = 2,2'-diphenyldicarboxylate and BTB = 1,4-bis(1,2,4-triazol-1-yl)butane) was successfully constructed via a hydrothermal reaction. Structural analysis shows that the synthesized Cd-MOF is a three-dimensional (3D) architecture crystallized in the hexagonal system with a chiral space group P61. Powder X-ray diffraction experiments and thermogravimetric analysis reveal that the constructed Cd-MOF has a high chemical and thermal stability. A study of additional mechanical properties indicates that it exhibits a moderate stiffness with the average values of Young's modulus (E) and H as 11.3(2) and 0.9(7) GPa, respectively. The luminescence properties of the Cd-MOF were further studied. The result shows that it could be an effective sensor to the organic nitrobenzene molecule via a strong quenching effect, and also to the inorganic Tb(III) ion by a strong green emission effect. Moreover, when loading bimetal ions (Eu(III) and Tb(III) into the Cd-MOF/methanol suspension, tunable visible luminescence can also be achieved by carefully adjusting the excitation wavelengths.

Asymptomatic memory CD8+ T cells

Science.gov (United States)

Khan, Arif Azam; Srivastava, Ruchi; Lopes, Patricia Prado; Wang, Christine; Pham, Thanh T; Cochrane, Justin; Thai, Nhi Thi Uyen; Gutierrez, Lucas; BenMohamed, Lbachir

2014-01-01

Generation and maintenance of high quantity and quality memory CD8+ T cells determine the level of protection from viral, bacterial, and parasitic re-infections, and hence constitutes a primary goal for T cell epitope-based human vaccines and immunotherapeutics. Phenotypically and functionally characterizing memory CD8+ T cells that provide protection against herpes simplex virus type 1 and type 2 (HSV-1 and HSV-2) infections, which cause blinding ocular herpes, genital herpes, and oro-facial herpes, is critical for better vaccine design. We have recently categorized 2 new major sub-populations of memory symptomatic and asymptomatic CD8+ T cells based on their phenotype, protective vs. pathogenic function, and anatomical locations. In this report we are discussing a new direction in developing T cell-based human herpes vaccines and immunotherapeutics based on the emerging new concept of “symptomatic and asymptomatic memory CD8+ T cells.” PMID:24499824

Diastereoselective Synthesis of Novel Heterocyclic Scaffolds through Tandem Petasis 3-Component/Intramolecular Diels-Alder and ROM-RCM Reactions

DEFF Research Database (Denmark)

Ishøy, Mette; Petersen, Rico; Petersen, Michael Åxman

2017-01-01

A high-yielding, stereoselective and extraordinarily complexity generatingPetasis 3-component/intramolecular Diels-Alderreaction has been developed. In combination with ROM-RCM, rapid access to complex sp3-rich heterocyclic scaffolds amenableto subsequent functionalization and library synthesis...

Fabrication of transparent TiO2 nanotube-based photoanodes for CdS/CdTe quantum co-sensitized solar cells

Science.gov (United States)

Gualdrón-Reyes, A. F.; Cárdenas-Arenas, A.; Martínez, C. A.; Kouznetsov, V. V.; Meléndez, A. M.

2017-01-01

In order to fabricate a solar cell, ordered TiO2 nanotube (TNT) arrays were prepared by double anodization. TNT arrays with variable lengths were obtained by changing the duration of the anodizing process of up to 3h. TNT membranes were transferred to indium tin oxide substrates and attached with a B-TiO2 sol. TNT photoanode with the best photoelectrochemical performance was sensitized with CdS by SILAR method. On other hand, CdTe quantum dots prepared via colloidal synthesis were deposited on TNT photoanodes for 2h, 4h and 6h. In addition, TNT/CdS was loaded with CdTe quantum dots for 4 h. Morphology and chemical modification of TiO2 were characterized by FESEM and XPS, while their photoelectrochemical performance was measured by open-circuit photopotential and photovoltammetry under visible light. TiO2 nanotubes grown during 2.5h showed the highest photocurrent due to presence of Ti3+ donor states by N and F co-doping, increasing the number of photogenerated electrons transported to back collector. TNT/CdS/CdTe photoanode reach the highest conversion efficiency under AM 1.5G simulated solar illumination.

Using a Multimedia Tool to Improve Cardiac Auscultation Knowledge and Skills

Science.gov (United States)

Stern, David T; Mangrulkar, Rajesh S; Gruppen, Larry D; Lang, Angela L; Grum, Cyril M; Judge, Richard D

2001-01-01

OBJECTIVE Today's medical school graduates have significant deficits in physical examination skills. Medical educators have been searching for methods to effectively teach and maintain these skills in students. The objective of this study was to determine if an auscultation curriculum centered on a portable multimedia CD-ROM was effective in producing and maintaining significant gains in cardiac auscultatory skills. DESIGN Controlled cohort study PARTICIPANTS All 168 third-year medical students at 1 medical school in an academic medical center. INTERVENTIONS Students were tested before and after exposure to 1 or more elements of the auscultation curriculum: teaching on ward/clinic rotations, CD-ROM comprehensive cases with follow-up seminars, and a CD-ROM 20-case miniseries. The primary outcome measures were student performance on a 10-item test of auscultation skill (listening and identifying heart sound characteristics) and a 30-item test of auscultation knowledge (factual questions about auscultation). A subset of students was tested for attenuation effects 9 or 12 months after the intervention. RESULTS Compared with the control group (1 month clinical rotation alone), students who were also exposed to the CD-ROM 20-case miniseries had significant improvements in auscultation skills scores (P auscultation knowledge beyond the miniseries alone (P auscultation skills. Students' auscultation knowledge diminished one year after the intervention, but auscultation skills did not. CONCLUSION In addition to the standard curriculum of ward and conference teaching, portable multimedia tools may help improve quality of physical examination skills. PMID:11722691

Effect of Ankle Range of Motion (ROM) and Lower-Extremity Muscle Strength on Static Balance Control Ability in Young Adults: A Regression Analysis.

Science.gov (United States)

Kim, Seong-Gil; Kim, Wan-Soo

2018-05-15

BACKGROUND The purpose of this study was to investigate the effect of ankle ROM and lower-extremity muscle strength on static balance control ability in young adults. MATERIAL AND METHODS This study was conducted with 65 young adults, but 10 young adults dropped out during the measurement, so 55 young adults (male: 19, female: 36) completed the study. Postural sway (length and velocity) was measured with eyes open and closed, and ankle ROM (AROM and PROM of dorsiflexion and plantarflexion) and lower-extremity muscle strength (flexor and extensor of hip, knee, and ankle joint) were measured. Pearson correlation coefficient was used to examine the correlation between variables and static balance ability. Simple linear regression analysis and multiple linear regression analysis were used to examine the effect of variables on static balance ability. RESULTS In correlation analysis, plantarflexion ROM (AROM and PROM) and lower-extremity muscle strength (except hip extensor) were significantly correlated with postural sway (psimple correlation analysis, all variables that passed the correlation analysis procedure had significant influence (plinear regression analysis, plantar flexion PROM with eyes open significantly influenced sway length (B=0.681) and sway velocity (B=0.011). CONCLUSIONS Lower-extremity muscle strength and ankle plantarflexion ROM influenced static balance control ability, with ankle plantarflexion PROM showing the greatest influence. Therefore, both contractile structures and non-contractile structures should be of interest when considering static balance control ability improvement.

Exploring the Tuolumne River:An Interactive CD ROM on Fluvial Processes

Science.gov (United States)

Reid, J. B.; Murray, D. D.; Sammons, J. I.; Woolf, B.; Kidder, J.

2001-12-01

We have created an electronic field investigation to help students discover the dynamics of river processes using the example of the Tuolumne River, in Yosemite National Park. The experience simulates a field trip to Tuolumne Meadows, where the students make a series of visual observations based on ground and aerial photographs. We want them to build as full a set of objective observations as possible before they engage in interpretation. The program records the specific locations in the photographs where the observations have been made, allowing an electronic assessment of the diversity of the students' descriptions. Students also "acquire" real field data (bathymetry, flow and grain size distributions, and the outer bank position through time) in a two stage process: (1) they predict the bathymetry, the flow patterns, etc. based on a careful scrutiny of the photographs and (2) they "do the experiments" to get the real field data. The computer then evaluates the match in each case, and asks a series of tailored socratic questions to lead the students to a richer understanding. When the "observations" are complete, we help them organize a logically sequential Results Section, and then a self-consistent hypothesis. Finally, for further investigation, we provide a set of photographs of other ivers, each of which has a rich "story" of its own. Our goals for this project are: (1) to have students discover for themselves how rivers "work" at their own pace and level of sophistication, and (2) to model the scientific method so that it can applied to other geologic investigations.

CD4+/CD8+ double-positive T cells

DEFF Research Database (Denmark)

Overgaard, Nana H; Jung, Ji-Won; Steptoe, Raymond J

2015-01-01

CD4(+)/CD8(+) DP thymocytes are a well-described T cell developmental stage within the thymus. However, once differentiated, the CD4(+) lineage or the CD8(+) lineage is generally considered to be fixed. Nevertheless, mature CD4(+)/CD8(+) DP T cells have been described in the blood and peripheral...... cells, CD4(+)/CD8(+) T cell populations, outside of the thymus, have recently been described to express concurrently ThPOK and Runx3. Considerable heterogeneity exists within the CD4(+)/CD8(+) DP T cell pool, and the function of CD4(+)/CD8(+) T cell populations remains controversial, with conflicting...... reports describing cytotoxic or suppressive roles for these cells. In this review, we describe how transcriptional regulation, lineage of origin, heterogeneity of CD4 and CD8 expression, age, species, and specific disease settings influence the functionality of this rarely studied T cell population....

Proceedings of the 4th European conference on protection against radon at home and at work. Conference programme and session presentations

International Nuclear Information System (INIS)

2004-01-01

The conference was divided into 6 sections as follows (the numbers of PDF files included in the CD-ROM are given in parentheses): 1. Radon measurement in dwellings (7); 2. Radon measurement at workplaces (14); 3. Methods of measurement and devices (16); 4. Remedial measures and techniques (5); 5. Preventive measures and techniques (10); and 6. National radon programmes (6). In addition, the CD-ROM contains 3, 11, 9, 5, 6, and 6 PowerPoint presentations shown in the six sections, respectively, plus a total of 93 abstracts, mostly of posters. (P.A.)

Magnetismo 2000

Science.gov (United States)

Cardús, J. O.; Curto, J. J.; Sanclement, E.; Torta, J. M.

This CD-ROM presents the digital version of the Boletin del Observatorio del Ebro Magnetismo. It contains data obtained in the Magnetic Station of the Ebre Observatory during the year 2000. The structure of the CD-ROM consists of one directory numbered with the year of the measurement. There, it could be found the bulletin as printable sheets (Year.pdf) generate with Adobe Acrobat and data files in plain ASCII text (Year.wdc) readable with any text editor. These data files were compiled according to the data exchange format recommended by the IAGA-2002.

Magnetismo 2002

Science.gov (United States)

Cardús, J. O.; Curto, J. J.; Sanclement, E.; Torta, J. M.

This CD-ROM presents the digital version of the Boletin del Observatorio del Ebro Magnetismo. It contains data obtained in the Magnetic Station of the Ebre Observatory during the year 2002. The structure of the CD-ROM consists of one directory numbered with the year of the measurement. There, it could be found the bulletin as printable sheets (Year.pdf) generate with Adobe Acrobat and data files in plain ASCII text (Year.wdc) readable with any text editor. These data files were compiled according to the data exchange format recommended by the IAGA-2002.

Magnetismo 2003

Science.gov (United States)

Cardús, J. O.; Curto, J. J.; Sanclement, E.; Torta, J. M.

This CD-ROM presents the digital version of the Boletin del Observatorio del Ebro Magnetismo. It contains data obtained in the Magnetic Station of the Ebre Observatory during the year 2003. The structure of the CD-ROM consists of one directory numbered with the year of the measurement. There, it could be found the bulletin as printable sheets (Year.pdf) generate with Adobe Acrobat and data files in plain ASCII text (Year.wdc) readable with any text editor. These data files were compiled according to the data exchange format recommended by the IAGA-2002.

Magnetismo 2001

Science.gov (United States)

Cardús, J. O.; Curto, J. J.; Sanclement, E.; Torta, J. M.

This CD-ROM presents the digital version of the Boletin del Observatorio del Ebro Magnetismo. It contains data obtained in the Magnetic Station of the Ebre Observatory during the year 2001. The structure of the CD-ROM consists of one directory numbered with the year of the measurement. There, it could be found the bulletin as printable sheets (Year.pdf) generate with Adobe Acrobat and data files in plain ASCII text (Year.wdc) readable with any text editor. These data files were compiled according to the data exchange format recommended by the IAGA-2002.

NSOM/QD-Based Visualization of GM1 Serving as Platforms for TCR/CD3 Mediated T-Cell Activation

Directory of Open Access Journals (Sweden)

Liyun Zhong

2013-01-01

Full Text Available Direct molecular imaging of nanoscale relationship between T-cell receptor complexes (TCR/CD3 and gangliosidosis GM1 before and after T-cell activation has not been reported. In this study, we made use of our expertise of near-field scanning optical microscopy(NSOM/immune-labeling quantum dots- (QD-based dual-color imaging system to visualize nanoscale profiles for distribution and organization of TCR/CD3, GM1, as well as their nanospatial relationship and their correlation with PKCθ signaling cascade during T-cell activation. Interestingly, after anti-CD3/anti-CD28 Ab co-stimulation, both TCR/CD3 and GM1 were clustered to form nanodomains; moreover, all of TCR/CD3 nanodomains were colocalized with GM1 nanodomains, indicating that the formation of GM1 nanodomains was greatly correlated with TCR/CD3 mediated signaling. Specially, while T-cells were pretreated with PKCθ signaling inhibitor rottlerin to suppress IL-2 cytokine production, no visible TCR/CD3 nanodomains appeared while a lot of GM1 nanodomains were still observed. However, while T-cells are pretreated with PKCαβ signaling inhibitor GÖ6976 to suppress calcium-dependent manner, all of TCR/CD3 nanodomains were still colocalized with GM1 nanodomains. These findings possibly support the notion that the formation of GM1 nanodomains indeed serves as platforms for the recruitment of TCR/CD3 nanodomains, and TCR/CD3 nanodomains are required for PKCθ signaling cascades and T-cell activation

Human CD56bright NK Cells

DEFF Research Database (Denmark)

Michel, Tatiana; Poli, Aurélie; Cuapio, Angelica

2016-01-01

Human NK cells can be subdivided into various subsets based on the relative expression of CD16 and CD56. In particular, CD56(bright)CD16(-/dim) NK cells are the focus of interest. They are considered efficient cytokine producers endowed with immunoregulatory properties, but they can also become c...... NK cell subsets is not fully defined, nor is their precise hematopoietic origin. In this article, we summarize recent studies about CD56(bright) NK cells in health and disease and briefly discuss the current controversies surrounding them....

Diseño y propuesta de implementación de perfiles por competencias, valoración y clasificación; como base para un esquema de compensaciones caso Empresa Pública Metropolitana de Agua Potable y Saneamiento - EPMAPS de la ciudad de Quito

OpenAIRE

Cruz Mena, Lorena Margarita; Lara Carrera, César Eduardo

2013-01-01

203 hojas : ilustraciones, 29 x 21 cm + CD-ROM 5060 Esta investigación propone para la Empresa Pública Metropolitana de Agua Potable y Saneamiento "EPMAPS" de La ciudad de Quito, un modelo de levantamiento, administración, valoración y clasificación de puestos como base para la estructuración de puestos y salariales. Para la aplicación del Reglamento Interno de Gestión y Administración del Talento Humano, "RIATH", que dispone esta Empresa es necesario, el desarrollo de políticas, normas, m...

Tech Notebook: E-Reference Tools.

Science.gov (United States)

Sassman, Charlotte

1999-01-01

Two resources to help students conduct research are the new CD-ROM versions of the Encarta Encyclopedia Deluxe 2000 (for strong readers, grades 5-8) and the Year 2000 Grolier Multimedia Encyclopedia (for strong readers, grades 3 and up). By supplementing traditional text-based information with specialized features (e.g., virtual tours and video…

CD8{sup +}CD25{sup +} T cells reduce atherosclerosis in apoE(−/−) mice

Energy Technology Data Exchange (ETDEWEB)

Zhou, Jianchang; Dimayuga, Paul C.; Zhao, Xiaoning; Yano, Juliana; Lio, Wai Man; Trinidad, Portia; Honjo, Tomoyuki; Cercek, Bojan; Shah, Prediman K.; Chyu, Kuang-Yuh, E-mail: Chyuk@cshs.org

2014-01-17

Highlights: •The role of a sub-population of CD8{sup +} T cells with suppressor functions was investigated in atherosclerosis. •CD8{sup +}CD25{sup +} T cells from adult apoE(−/−) mice had phenotype characteristics of T suppressor cells. •These CD8{sup +}CD25{sup +} T cells reduced CD4{sup +} T cell proliferation and CD8{sup +} cytotoxic activity in vitro. •Adoptive transfer of CD8{sup +}CD25{sup +} T cells significantly reduced atherosclerosis. •CD8{sup +}CD25{sup +} T cells have a suppressive function in atherosclerosis. -- Abstract: Background: It is increasingly evident that CD8{sup +} T cells are involved in atherosclerosis but the specific subtypes have yet to be defined. CD8{sup +}CD25{sup +} T cells exert suppressive effects on immune signaling and modulate experimental autoimmune disorders but their role in atherosclerosis remains to be determined. The phenotype and functional role of CD8{sup +}CD25{sup +} T cells in experimental atherosclerosis were investigated in this study. Methods and results: CD8{sup +}CD25{sup +} T cells were observed in atherosclerotic plaques of apoE(−/−) mice fed hypercholesterolemic diet. Characterization by flow cytometric analysis and functional evaluation using a CFSE-based proliferation assays revealed a suppressive phenotype and function of splenic CD8{sup +}CD25{sup +} T cells from apoE(−/−) mice. Depletion of CD8{sup +}CD25{sup +} from total CD8{sup +} T cells rendered higher cytolytic activity of the remaining CD8{sup +}CD25{sup −} T cells. Adoptive transfer of CD8{sup +}CD25{sup +} T cells into apoE(−/−) mice suppressed the proliferation of splenic CD4{sup +} T cells and significantly reduced atherosclerosis in recipient mice. Conclusions: Our study has identified an athero-protective role for CD8{sup +}CD25{sup +} T cells in experimental atherosclerosis.

Dificultăți de traducere în limba română a Aforismelor lui Arthur Schopenhauer. O analiză contrastiv-diacronică (I

Directory of Open Access Journals (Sweden)

Cecilia-Iuliana Vârlan

2016-02-01

Full Text Available Lucrarea de față se concentrează asupra unei opere de maturitate a filozofului german Arthur Schopenhauer, Aforisme asupra înțelepciunii în viață, și asupra singurei versiuni românești a acesteia, realizate de Titu Maiorescu la sfîrșitul secolului al XIX-lea. Existența a cinci variante ale versiunii românești, publicate de traducătorul însuși de-a lungul a patru decenii, reprezintă o dovadă clară a faptului că transpunerea în românește a acestui text de filozofie practică a incumbat o serie întreagă de dificultăți de traducere. Urmărind modul în care Titu Maiorescu a încercat să rezolve aceste dificultăți, prin adoptarea anumitor soluții traductologice, am realizat o analiză a acestora, din perspectivă lingvistică, cercetarea urmînd concomitent două direcții: contrastivă (rezultată din supra- punerea textului-sursă și a textului-țintă și diacronică (urmărind intervențiile realizate de același traducător asupra propriului text, la intervale de timp diferite. Demersul de analiză lingvistică a traducerii unui text filozofic ni s-a părut util nu doar studiului nostru, ci și viitorilor eventuali traducători ai Aforismelor, a căror intenție ar putea fi aceea de a adapta discursul versiunii românești a lui Titu Maiorescu la limba română contemporană, ținînd seama de evoluția evidentă a acesteia și, mai ales, a componentei sale de limbaj filozofic.

Diseño de un sistema de gestión de seguridad de la información para Cooperativas de Ahorro y Crédito en base a la norma ISO 27001

OpenAIRE

Mantilla Guerra, Aníbal Rubén

2009-01-01

209 hojas : ilustraciones, 29 x 21 cm + CD-ROM 2254 En esta Tesis se diseñó un Sistema de Gestión de Seguridad de la Información para Cooperativas de Ahorro y Crédito, en base a la norma ISO 27001, la Ley de la Superintendencia de Bancos y Seguros, la Ley de Cooperativas de Ahorro y Crédito, considerando además, su evolución y problemática en el Sistema Financiero Nacional. De manera metodológica, científica y objetiva, se muestra como identificar, evaluar y gestionar el riesgo, en Coopera...

Selection of Shared and Neoantigen-Reactive T Cells for Adoptive Cell Therapy Based on CD137 Separation

Directory of Open Access Journals (Sweden)

Sivan Seliktar-Ofir

2017-10-01

Full Text Available Adoptive cell therapy (ACT of autologous tumor infiltrating lymphocytes (TIL is an effective immunotherapy for patients with solid tumors, yielding objective response rates of around 40% in refractory patients with metastatic melanoma. Most clinical centers utilize bulk, randomly isolated TIL from the tumor tissue for ex vivo expansion and infusion. Only a minor fraction of the administered T cells recognizes tumor antigens, such as shared and mutation-derived neoantigens, and consequently eliminates the tumor. Thus, there are many ongoing effects to identify and select tumor-specific TIL for therapy; however, those approaches are very costly and require months, which is unreasonable for most metastatic patients. CD137 (4-1BB has been identified as a co-stimulatory marker, which is induced upon the specific interaction of T cells with their target cell. Therefore, CD137 can be a useful biomarker and an important tool for the selection of tumor-reactive T cells. Here, we developed and validated a simple and time efficient method for the selection of CD137-expressing T cells for therapy based on magnetic bead separation. CD137 selection was performed with clinical grade compliant reagents, and TIL were expanded in a large-scale manner to meet cell numbers required for the patient setting in a GMP facility. For the first time, the methodology was designed to comply with both clinical needs and limitations, and its feasibility was assessed. CD137-selected TIL demonstrated significantly increased antitumor reactivity and were enriched for T cells recognizing neoantigens as well as shared tumor antigens. CD137-based selection enabled the enrichment of tumor-reactive T cells without the necessity of knowing the epitope specificity or the antigen type. The direct implementation of the CD137 separation method to the cell production of TIL may provide a simple way to improve the clinical efficiency of TIL ACT.

Nanocrystalline CdSnO3 Based Room Temperature Methanol Sensor

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Shanabhau BAGUL

2017-04-01

Full Text Available Synthesis of nanocrystalline CdSnO3 powder by ultrasonic atomizer assisted wet chemical method is reported in this paper. Synthesized CdSnO3 powder was characterized by X-Ray Diffraction (XRD, Field Emission Scanning Electron Microscopy (FESEM and Transmission Electron Microscopy (TEM to examine phase and microstructure. FESEM and TEM analysis reveals that the CdSnO3 powder prepared here is porous monodisperse nanocrystalline in nature, with average particle size of approximately 17 nm or smaller. The material is also characterized by UV-Visible and Photoluminescence (PL spectroscopy. Thick films of synthesized CdSnO3 powder fired at 850 0C are made by using screen printing method. The films surface is modified by using dipping method. CuCl2 (0.005 M dipped (for 2 min thick film shows high response (R= 477 to 100 ppm methanol at room temperature (35 0C. The sensor shows good selectivity and fast response recovery time to methanol. The excellent methanol sensing performance, particularly high response values is observed to be mainly due to porous CdSnO3 surface.

Read-only-memory-based quantum computation: Experimental explorations using nuclear magnetic resonance and future prospects

International Nuclear Information System (INIS)

Sypher, D.R.; Brereton, I.M.; Wiseman, H.M.; Hollis, B.L.; Travaglione, B.C.

2002-01-01

Read-only-memory-based (ROM-based) quantum computation (QC) is an alternative to oracle-based QC. It has the advantages of being less 'magical', and being more suited to implementing space-efficient computation (i.e., computation using the minimum number of writable qubits). Here we consider a number of small (one- and two-qubit) quantum algorithms illustrating different aspects of ROM-based QC. They are: (a) a one-qubit algorithm to solve the Deutsch problem; (b) a one-qubit binary multiplication algorithm; (c) a two-qubit controlled binary multiplication algorithm; and (d) a two-qubit ROM-based version of the Deutsch-Jozsa algorithm. For each algorithm we present experimental verification using nuclear magnetic resonance ensemble QC. The average fidelities for the implementation were in the ranges 0.9-0.97 for the one-qubit algorithms, and 0.84-0.94 for the two-qubit algorithms. We conclude with a discussion of future prospects for ROM-based quantum computation. We propose a four-qubit algorithm, using Grover's iterate, for solving a miniature 'real-world' problem relating to the lengths of paths in a network

CD4+ Primary T Cells Expressing HCV-Core Protein Upregulate Foxp3 and IL-10, Suppressing CD4 and CD8 T Cells

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Aguado, Enrique; Garcia-Cozar, Francisco

2014-01-01

Adaptive T cell responses are critical for controlling HCV infection. While there is clinical evidence of a relevant role for regulatory T cells in chronic HCV-infected patients, based on their increased number and function; mechanisms underlying such a phenomena are still poorly understood. Accumulating evidence suggests that proteins from Hepatitis C virus can suppress host immune responses. We and others have shown that HCV is present in CD4+ lymphocytes from chronically infected patients and that HCV-core protein induces a state of unresponsiveness in the CD4+ tumor cell line Jurkat. Here we show that CD4+ primary T cells lentivirally transduced with HCV-core, not only acquire an anergic phenotype but also inhibit IL-2 production and proliferation of bystander CD4+ or CD8+ T cells in response to anti-CD3 plus anti-CD28 stimulation. Core-transduced CD4+ T cells show a phenotype characterized by an increased basal secretion of the regulatory cytokine IL-10, a decreased IFN-γ production upon stimulation, as well as expression of regulatory T cell markers, CTLA-4, and Foxp3. A significant induction of CD4+CD25+CD127lowPD-1highTIM-3high regulatory T cells with an exhausted phenotype was also observed. Moreover, CCR7 expression decreased in HCV-core expressing CD4+ T cells explaining their sequestration in inflamed tissues such as the infected liver. This work provides a new perspective on de novo generation of regulatory CD4+ T cells in the periphery, induced by the expression of a single viral protein. PMID:24465502

CD4+ primary T cells expressing HCV-core protein upregulate Foxp3 and IL-10, suppressing CD4 and CD8 T cells.

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Cecilia Fernandez-Ponce

Full Text Available Adaptive T cell responses are critical for controlling HCV infection. While there is clinical evidence of a relevant role for regulatory T cells in chronic HCV-infected patients, based on their increased number and function; mechanisms underlying such a phenomena are still poorly understood. Accumulating evidence suggests that proteins from Hepatitis C virus can suppress host immune responses. We and others have shown that HCV is present in CD4+ lymphocytes from chronically infected patients and that HCV-core protein induces a state of unresponsiveness in the CD4+ tumor cell line Jurkat. Here we show that CD4+ primary T cells lentivirally transduced with HCV-core, not only acquire an anergic phenotype but also inhibit IL-2 production and proliferation of bystander CD4+ or CD8+ T cells in response to anti-CD3 plus anti-CD28 stimulation. Core-transduced CD4+ T cells show a phenotype characterized by an increased basal secretion of the regulatory cytokine IL-10, a decreased IFN-γ production upon stimulation, as well as expression of regulatory T cell markers, CTLA-4, and Foxp3. A significant induction of CD4+CD25+CD127(lowPD-1(highTIM-3(high regulatory T cells with an exhausted phenotype was also observed. Moreover, CCR7 expression decreased in HCV-core expressing CD4+ T cells explaining their sequestration in inflamed tissues such as the infected liver. This work provides a new perspective on de novo generation of regulatory CD4+ T cells in the periphery, induced by the expression of a single viral protein.

Immunotherapy of non-Hodgkin lymphoma with a defined ratio of CD8+ and CD4+ CD19-specific chimeric antigen receptor-modified T cells

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Turtle, Cameron J.; Hanafi, Laïla-Aïcha; Berger, Carolina; Hudecek, Michael; Pender, Barbara; Robinson, Emily; Hawkins, Reed; Chaney, Colette; Cherian, Sindhu; Chen, Xueyan; Soma, Lorinda; Wood, Brent; Li, Daniel; Heimfeld, Shelly; Riddell, Stanley R.; Maloney, David G.

2016-01-01

CD19-specific chimeric antigen receptor (CAR)-modified T cells have antitumor activity in B cell malignancies, but factors that impact toxicity and efficacy have been difficult to define because of differences in lymphodepletion regimens and heterogeneity of CAR-T cells administered to individual patients. We conducted a clinical trial in which CD19 CAR-T cells were manufactured from defined T cell subsets and administered in a 1:1 CD4+:CD8+ ratio of CAR-T cells to 32 adults with relapsed and/or refractory B cell non-Hodgkin lymphoma after cyclophosphamide (Cy)-based lymphodepletion chemotherapy with or without fludarabine (Flu). Patients who received Cy/Flu lymphodepletion had markedly increased CAR-T cell expansion and persistence, and higher response rates (50% CR, 72% ORR, n=20) than patients who received Cy-based lymphodepletion without Flu (8% CR, 50% ORR, n=12). The complete response (CR) rate in patients treated with Cy/Flu at the maximally tolerated dose was 64% (82% ORR, n=11). Cy/Flu minimized the effects of an immune response to the murine scFv component of the CAR, which limited CAR-T cell expansion, persistence, and clinical efficacy in patients who received Cy-based lymphodepletion without Flu. Severe cytokine release syndrome (sCRS) and grade ≥ 3 neurotoxicity were observed in 13% and 28% of all patients, respectively. Serum biomarkers one day after CAR-T cell infusion correlated with subsequent development of sCRS and neurotoxicity. Immunotherapy with CD19 CAR-T cells in a defined CD4+:CD8+ ratio allowed identification of correlative factors for CAR-T cell expansion, persistence, and toxicity, and facilitated optimization of a lymphodepletion regimen that improved disease response and overall and progression-free survival. PMID:27605551

High-resolution Compton cameras based on Si/CdTe double-sided strip detectors

International Nuclear Information System (INIS)

Odaka, Hirokazu; Ichinohe, Yuto; Takeda, Shin'ichiro; Fukuyama, Taro; Hagino, Koichi; Saito, Shinya; Sato, Tamotsu; Sato, Goro; Watanabe, Shin; Kokubun, Motohide; Takahashi, Tadayuki; Yamaguchi, Mitsutaka

2012-01-01

We have developed a new Compton camera based on silicon (Si) and cadmium telluride (CdTe) semiconductor double-sided strip detectors (DSDs). The camera consists of a 500-μm-thick Si-DSD and four layers of 750-μm-thick CdTe-DSDs all of which have common electrode configuration segmented into 128 strips on each side with pitches of 250μm. In order to realize high angular resolution and to reduce size of the detector system, a stack of DSDs with short stack pitches of 4 mm is utilized to make the camera. Taking advantage of the excellent energy and position resolutions of the semiconductor devices, the camera achieves high angular resolutions of 4.5° at 356 keV and 3.5° at 662 keV. To obtain such high resolutions together with an acceptable detection efficiency, we demonstrate data reduction methods including energy calibration using Compton scattering continuum and depth sensing in the CdTe-DSD. We also discuss imaging capability of the camera and show simultaneous multi-energy imaging.

CdS decorated rGO containing PVDF electrospun fiber based piezoelectric nanogenerator for mechanical energy harvesting application

Science.gov (United States)

Roy, Krittish; Mandal, Dipankar

2018-04-01

In this work, we demonstrate a simple and facile route ofcadmium sulfide (CdS) nanoparticle (NPs) grafted reduced graphene oxide (rGO) synthesis. It is found that a pinch (0.25 wt%) of as synthesisedCdS/rGOnanocompositecan induce more than 90% of electroactive phases in the electrospunpoly(vinylidene fluoride) (PVDF) nanofiber. Moreover, CdS/rGO nanocomposite doped PVDF nanofiber based nanogenerator (NG) can generate an output voltage of approximately 4 V upon repetitive finger imparting. Thus, the NG can be used as a mechanical energy harvester and power source for portable electronic and optoelectronic wearable devices.

Downregulation of CD44 reduces doxorubicin resistance of CD44+CD24- breast cancer cells

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Phuc PV

2011-06-01

Full Text Available Pham Van Phuc, Phan Lu Chinh Nhan, Truong Hai Nhung, Nguyen Thanh Tam, Nguyen Minh Hoang, Vuong Gia Tue, Duong Thanh Thuy, Phan Kim NgocLaboratory of Stem Cell Research and Application, University of Science, Vietnam National University, Ho Chi Minh, VietnamBackground: Cells within breast cancer stem cell populations have been confirmed to have a CD44+CD24- phenotype. Strong expression of CD44 plays a critical role in numerous types of human cancers. CD44 is involved in cell differentiation, adhesion, and metastasis of cancer cells.Methods: In this study, we reduced CD44 expression in CD44+CD24- breast cancer stem cells and investigated their sensitivity to an antitumor drug. The CD44+CD24- breast cancer stem cells were isolated from breast tumors; CD44 expression was downregulated with siRNAs followed by treatment with different concentrations of the antitumor drug.Results: The proliferation of CD44 downregulated CD44+CD24- breast cancer stem cells was decreased after drug treatment. We noticed treated cells were more sensitive to doxorubicin, even at low doses, compared with the control groups.Conclusions: It would appear that expression of CD44 is integral among the CD44+CD24- cell population. Reducing the expression level of CD44, combined with doxorubicin treatment, yields promising results for eradicating breast cancer stem cells in vitro. This study opens a new direction in treating breast cancer through gene therapy in conjunction with chemotherapy.Keywords: antitumor drugs, breast cancer stem cells, CD44, CD44+CD24- cells, doxorubicin

Percentages of CD4+CD161+ and CD4−CD8−CD161+ T Cells in the Synovial Fluid Are Correlated with Disease Activity in Rheumatoid Arthritis

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Jinlin Miao

2015-01-01

Full Text Available Objective. CD161 has been identified as a marker of human IL-17-producing T cells that are implicated in the pathogenesis of rheumatoid arthritis (RA. This study aimed to investigate the potential link between the percentage of CD161+ T cells and disease activity in RA patients. Methods. Peripheral blood (PB from 54 RA patients and 21 healthy controls was evaluated. Paired synovial fluid (SF (n = 17 was analyzed. CD161 expression levels on CD4+, CD8+, and CD4−CD8− T cells were assessed by flow cytometry. Results. The percentage of CD4+CD161+ T cells in RA SF was higher than RA PB, and it was positively correlated with DAS28, erythrocyte sedimentation rate (ESR, and C-reactive protein (CRP. CD4−CD8−CD161+ T cell percentage was decreased in RA PB and was further reduced in RA SF, and its level in SF was inversely correlated with DAS28, ESR, and CRP. However, CD8+CD161+ T cell percentage was neither changed in RA PB and SF nor correlated with disease activity indices. Conclusion. An increased CD4+CD161+ T cell percentage and a decreased CD4−CD8−CD161+ T cell percentage are present in RA SF and are associated with disease activity, and the accumulation of CD4+CD161+ T cells in SF may contribute to the local inflammation of RA.

Differential number of CD34+, CD133+ and CD34+/CD133+ cells in peripheral blood of patients with congestive heart failure

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Fritzenwanger M

2009-03-01

Full Text Available Abstract Background Endothelial progenitor cells (EPC which are characterised by the simulateous expression of CD34, CD133 and vascular endothelial growth receptor 2 (VEGF 2 are involved in the pathophysiology of congestive heart failure (CHF and their number and function is reduced in CHF. But so far our knowledge about the number of circulating hematopoietic stem/progenitor cells (CPC expressing the early hematopoietic marker CD133 and CD34 in CHF is spares and therefore we determined their number and correlated them with New York Heart Association (NYHA functional class. Methods CD34 and CD133 surface expression was quantified by flow cytometry in the peripheral venous blood of 41 healthy adults and 101 patients with various degrees of CHF. Results CD34+, CD133+ and CD34+/CD133+ cells correlated inversely with age. Both the number of CD34+ and of CD34+/CD133+ cells inversely correlated with NYHA functional class. The number of CD133+ cells was not affected by NYHA class. Furthermore the number of CD133+ cells did not differ between control and CHF patients. Conclusion In CHF the release of CD34+, CD133+ and CD34+/CD133+ cells from the bone marrow seems to be regulated differently. Modulating the releasing process in CHF may be a tool in CHF treatment.

A Survey of Recent Advances in Optical and Multimedia Information Technologies.

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Jessop, Deborah

1997-01-01

Examines developments in multimedia technologies and in the World Wide Web. Discusses CD-recordable, CD-rewritable, cable modems, personal digital assistants, digital video discs, interactivity and virtual worlds, advertising on the Web, and Intranets and CD-ROM networks. Eight tables and figures show costs, download time, estimated sales, storage…

High Efficiency Thin Film CdTe and a-Si Based Solar Cells: Final Technical Report, 4 March 1998--15 October 2001

Energy Technology Data Exchange (ETDEWEB)

Compaan, A. D.; Deng, X.; Bohn, R. G.

2003-10-01

This is the final report covering about 42 months of this subcontract for research on high-efficiency CdTe-based thin-film solar cells and on high-efficiency a-Si-based thin-film solar cells. Phases I and II have been extensively covered in two Annual Reports. For this Final Report, highlights of the first two Phases will be provided and then detail will be given on the last year and a half of Phase III. The effort on CdTe-based materials is led by Prof. Compaan and emphasizes the use of sputter deposition of the semiconductor layers in the fabrication of CdS/CdTe cells. The effort on high-efficiency a-Si materials is led by Prof. Deng and emphasizes plasma-enhanced chemical vapor deposition for cell fabrication with major efforts on triple-junction devices.

Photovoltaic efficiency of intermediate band solar cells based on CdTe/CdMnTe coupled quantum dots

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Prado, Silvio J.; Marques, Gilmar E.; Alcalde, Augusto M.

2017-11-01

In this work we show the calculation of optimized efficiencies of intermediate band solar cells (IBSCs) based on Mn-doped II-VI CdTe/CdMnTe coupled quantum dot (QD) structures. We focus our attention on the combined effects of geometrical and Mn-doping parameters on optical properties and solar cell efficiency. In the framework of {k \\cdot p} theory, we accomplish detailed calculations of electronic structure, transition energies, optical selection rules and their corresponding intra- and interband oscillator strengths. With these results and by following the intermediate band model, we have developed a strategy which allows us to find optimal photovoltaic efficiency values. We also show that the effects of band admixture which can lead to degradation of optical transitions and reduction of efficiency can be partly minimized by a careful selection of the structural parameters and Mn-concentration. Thus, the improvement of band engineering is mandatory for any practical implementation of QD systems as IBSC hardware. Finally, our calculations show that it is possible to reach significant efficiency, up to  ∼26%, by selecting a restricted space of parameters such as quantum dot size and shape and Mn-concentration effects, to improve the modulation of optical absorption in the structures.

Photovoltaic efficiency of intermediate band solar cells based on CdTe/CdMnTe coupled quantum dots.

Science.gov (United States)

Prado, Silvio J; Marques, Gilmar E; Alcalde, Augusto M

2017-11-08

In this work we show the calculation of optimized efficiencies of intermediate band solar cells (IBSCs) based on Mn-doped II-VI CdTe/CdMnTe coupled quantum dot (QD) structures. We focus our attention on the combined effects of geometrical and Mn-doping parameters on optical properties and solar cell efficiency. In the framework of [Formula: see text] theory, we accomplish detailed calculations of electronic structure, transition energies, optical selection rules and their corresponding intra- and interband oscillator strengths. With these results and by following the intermediate band model, we have developed a strategy which allows us to find optimal photovoltaic efficiency values. We also show that the effects of band admixture which can lead to degradation of optical transitions and reduction of efficiency can be partly minimized by a careful selection of the structural parameters and Mn-concentration. Thus, the improvement of band engineering is mandatory for any practical implementation of QD systems as IBSC hardware. Finally, our calculations show that it is possible to reach significant efficiency, up to  ∼26%, by selecting a restricted space of parameters such as quantum dot size and shape and Mn-concentration effects, to improve the modulation of optical absorption in the structures.

Changes in Reactivity In Vitro of CD4+CD25+ and CD4+CD25− T Cell Subsets in Transplant Tolerance

Science.gov (United States)

Hall, Bruce M.; Robinson, Catherine M.; Plain, Karren M.; Verma, Nirupama D.; Tran, Giang T.; Nomura, Masaru; Carter, Nicole; Boyd, Rochelle; Hodgkinson, Suzanne J.

2017-01-01

Transplant tolerance induced in adult animals is mediated by alloantigen-specific CD4+CD25+ T cells, yet in many models, proliferation of CD4+ T cells from hosts tolerant to specific-alloantigen in vitro is not impaired. To identify changes that may diagnose tolerance, changes in the patterns of proliferation of CD4+, CD4+CD25+, and CD4+CD25− T cells from DA rats tolerant to Piebald Virol Glaxo rat strain (PVG) cardiac allografts and from naïve DA rats were examined. Proliferation of CD4+ T cells from both naïve and tolerant hosts was similar to both PVG and Lewis stimulator cells. In mixed lymphocyte culture to PVG, proliferation of naïve CD4+CD25− T cells was greater than naïve CD4+ T cells. In contrast, proliferation of CD4+CD25− T cells from tolerant hosts to specific-donor PVG was not greater than CD4+ T cells, whereas their response to Lewis and self-DA was greater than CD4+ T cells. Paradoxically, CD4+CD25+ T cells from tolerant hosts did not proliferate to PVG, but did to Lewis, whereas naïve CD4+CD25+ T cells proliferate to both PVG and Lewis but not to self-DA. CD4+CD25+ T cells from tolerant, but not naïve hosts, expressed receptors for interferon (IFN)-γ and IL-5 and these cytokines promoted their proliferation to specific-alloantigen PVG but not to Lewis or self-DA. We identified several differences in the patterns of proliferation to specific-donor alloantigen between cells from tolerant and naïve hosts. Most relevant is that CD4+CD25+ T cells from tolerant hosts failed to proliferate or suppress to specific donor in the absence of either IFN-γ or IL-5. The proliferation to third-party and self of each cell population from tolerant and naïve hosts was similar and not affected by IFN-γ or IL-5. Our findings suggest CD4+CD25+ T cells that mediate transplant tolerance depend on IFN−γ or IL-5 from alloactivated Th1 and Th2 cells. PMID:28878770

Grafiskā stāstījuma uzbūve un trauma Hāleda Hoseinī grafiskajā romānā “Pūķa ķērājs”

OpenAIRE

Vanaga, Alīna

2016-01-01

Hāleda Hoseinī grafiskais romāns “Pūķa ķērājs”demonstrē grafisko romānu spēju vienlaicīgi uzrunāt lielu cilvēku daudzumu un tajā pašā laikā izteikt neaprakstāmo, kas apliecina to, ka grafiskie romāni ļoti labi prot darīt saprotamas tādas neaprakstāmas tēmas, kā trauma. Tādēļ, šī maģistra darba mērķis ir noteikt, kā grafiskā stāstījuma uzbūve attēlo traumu Hāleda Hoseinī grafiskajā romāna “Pūķa ķērājs” un kādu rezultātu tas rada. Iepriekš minētā mērķa sasniegšanai tika izvēlētas divas pētīšana...

Report on the EMBER Project--A European Multimedia Bioinformatics Educational Resource

Science.gov (United States)

Attwood, Terri K.; Selimas, Ioannis; Buis, Rob; Altenburg, Ruud; Herzog, Robert; Ledent, Valerie; Ghita, Viorica; Fernandes, Pedro; Marques, Isabel; Brugman, Marc

2005-01-01

EMBER was a European project aiming to develop bioinformatics teaching materials on the Web and CD-ROM to help address the recognised skills shortage in bioinformatics. The project grew out of pilot work on the development of an interactive web-based bioinformatics tutorial and the desire to repackage that resource with the help of a professional…

Poemele homerice în veșminte românești. O analiză diacronică (I

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Petre Gheorghe Bârlea

2015-07-01

Full Text Available Lucrarea pe care o propunem vizează istoria traducerilor românești ale poemelor homerice, din perspectiva evoluției limbii române literare. Pornim de la premisa că orice asemenea traducere reprezintă o probă de virtuozitate nu numai pentru traducătorul în cauză, ci și pentru limba și cultura modernă respectivă, așa încît este interesant de studiat modul în care dezvoltarea exegezei homerice și a teoriilor traductologice se manifestă în paralel cu etapele evoluției limbilor moderne. Grila de analiză va include, așadar, principii, metode și instrumente de lucru ale domeniilor amintite aici (istoria limbii, traductologie, dar și elemente împrumutate din gramatica constrastiv-tipologică, din filologie, în sensul restrîns al conceptului, din teoria mentalităților, istoria culturală ș.a. Demersul nostru evidențiază faptul că evoluția istorică a actului traducerii este marcată, în mod firesc, de personalitatea traducătorului (opțiuni teoretice, ideologice, pe lîngă competențe lingvistice, har poetic etc., dar și de contextul cultural al epocii și al spațiului respectiv. Pentru cultura română, cel puțin, putem constata că, în ansamblu, versiunea cea mai recentă este și cea mai reușită.

CDC staging based on absolute CD4 count and CD4 percentage in an HIV-1-infected Indian population: treatment implications

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Vajpayee, M; Kaushik, S; Sreenivas, V; Wig, N; Seth, P

2005-01-01

CD4+ T-cell levels are an important criterion for categorizing HIV-related clinical conditions according to the CDC classification system and are therefore important in the management of HIV by initiating antiretroviral therapy and prophylaxis for opportunistic infections due to HIV among HIV-infected individuals. However, it has been observed that the CD4 counts are affected by the geographical location, race, ethnic origin, age, gender and changes in total and differential leucocyte counts. In the light of this knowledge, we classified 600 HIV seropositive antiretroviral treatment (ART)-naïve Indian individuals belonging to different CDC groups A, B and C on the basis of CDC criteria of both CD4% and CD4 counts and receiver operating characteristic (ROC) curves were generated. Importantly, CDC staging on the basis of CD4% indicated significant clinical implications, requiring an early implementation of effective antiretroviral treatment regimen in HIV-infected individuals deprived of treatment when classified on the basis of CD4 counts. PMID:16045738

Effect of curcumin on the cell surface markers CD44 and CD24 in breast cancer.

Science.gov (United States)

Calaf, Gloria M; Ponce-Cusi, Richard; Abarca-Quinones, Jorge

2018-04-20

Human breast cell lines are often characterized based on the expression of the cell surface markers CD44 and CD24. CD44 is a type I transmembrane glycoprotein that regulates cell adhesion and cell-cell, as well as cell-extracellular matrix interactions. CD24 is expressed in benign and malignant solid tumors and is also involved in cell adhesion and metastasis. The aim of the present study was to investigate the effects of curcumin on the surface expression of CD44 and CD24 in breast epithelial cell lines. An established breast cancer model derived from the MCF-10F cell line was used. The results revealed that curcumin decreased CD44 and CD24 gene and protein expression levels in MCF-10F (normal), Alpha5 (premalignant) and Tumor2 (malignant) cell lines compared with the levels in their counterpart control cells. Flow cytometry revealed that the CD44+/CD24+ cell subpopulation was greater than the CD44+/CD24- subpopulation in these three cell lines. Curcumin increased CD44+/CD24+ to a greater extent and decreased CD44+/CD24- subpopulations in the normal MCF-10F and the pre-tumorigenic Alpha5 cells, but had no significant effect on Tumor2 cells compared with the corresponding control cells. Conversely, curcumin increased CD44 and decreased CD24 gene expression in MCF-7 breast cancer cells, and decreased CD44 gene expression in MDA-MB-231 cell line, while CD24 was not present in these cells. Curcumin did not alter the CD44+/CD24+ or CD44+/CD24- subpopulations in the MCF-7 cell line. However, it increased CD44+/CD24+ and decreased CD44+/CD24- subpopulations in MDA-MB-231 cells. In breast cancer specimens from patients, normal tissues were negative for CD44 and CD24 expression, while benign lesions were positive for both markers, and malignant tissues were found to be negative for CD44 and positive for CD24 in most cases. In conclusion, these results indicated that curcumin may be used to improve the proportion of CD44+/CD24+ cells and decrease the proportion of CD44

Changes and clinical significance of CD4+CD25+CD127- regulatory T cells in Graves disease

International Nuclear Information System (INIS)

Zou Jintao; Yu Peiling; Dong Jingwei; Liao Qihong; Liu Dongliang; Zeng Hongyi

2012-01-01

Objective: To investigate the mechanism of Graves disease by observing the changes of CD4 + CD25 + CD127 - regulatory T cells (Treg) population in the patients. Methods: Flow cytometry was used to detect the proportion of CD4 + CD25 + CD127 - Treg of CD4 + T cells in 90 Graves disease patients (Graves disease group) and 50 healthy adults (control group). Thyroid function and autoantibody levels were determined simultaneously. The t test was adopted for comparison between groups. The relationship between CD4 + CD25 + CD127 - Treg and thyroid function was analyzed by linear correlation analysis. Results: The percentages of CD4 + CD25 + CD127 - Treg in Graves disease group and control group were 1.39%±1.09% and 4.59%±1.14% separately. There was significant difference between the two groups (t=16.4, P<0.01). There were negative correlation between CD4 + CD25 + CD127 - Treg percentages and total triiodothyronine, total thyroxine,free triiodothyronine, free thyroxine and thyrotropin receptor antibody,thyroglobulin antibody, thyroid microsomal antibody (r=-0.62, -0.65, -0.56, -0.71, -0.50, -0.15, all P<0.01). Conclusions: The reduction of CD4 + CD25 + CD127 - Treg percentages in Graves disease group and close relations of CD4 + CD25 + CD127 - Treg with thyroid function and thyroid autoantibody levels suggest that CD4 + CD25 + CD127 - Treg decrease in the number may be associated with the onset of Graves disease. CD4 + CD25 + CD127 - may be the specific marker of Treg. (authors)

Enciclopédia eletrônica: semelhanças e diferenças com o documento tradicional 10.5007/1518-2924.2002v7n14p19

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Magda Chagas Teixeira

2002-01-01

Full Text Available Acreditando que o estudo aprofundado dos documentos eletrônicos poderá contribuir para o seu aperfeiçoamento enquanto ferramentas importantes que são na disseminação e recuperação de informações, realiza-se, neste trabalho, uma análise do Almanaque Abril CD-ROM 98, procurando conhecer suas características e potencialidades, bem como suas semelhanças e diferenças com a enciclopédia tradicional. Para tanto, toma-se como base o trabalho desenvolvido por Hoey (1986 com relação às obras de referência, por ele denominadas de Colônias de Discursos. Após a análise, foi possível perceber que todas as características apresentadas pelo autor podem ser encontradas no Almanaque Abril CD-ROM 98, sendo que muitas delas aparecem de forma acentuada devido aos recursos oferecidos pela recuperação eletrônica de informações.

CdSe-based quantum dot nanostructures: MBE growth, properties and applications

International Nuclear Information System (INIS)

Ivanov, S.V.

2004-01-01

The paper presents an overview of the recent results of novel CdSe quantum dot (QD) fabrication techniques with the main emphasis on a stressor-controlled self-organization process resulting in nucleation of the optically active up to room temperature real CdSe QDs with a narrower size distribution, a higher density and a high Cd content. The main idea of the stressor-controlled epitaxy is the intentional introduction of a super-strained fractional monolayer of a much higher lattice-mismatch compound - stressor - to create strong local stress fields on the growth surface which govern self-assembling of the main QD material. The studies were performed on a type-II non-common atom CdSe/BeTe system, where CdTe (Δa/a∼14%) and BeSe (Δa/a∼-10%) interface bonds play the role of intrinsic stressors. Both experimental data (growth, structural and optical characterization) and Monte Carlo simulation of the growth process are presented

Interactive CD based training on NDA instruments for facility operators and international inspectors

International Nuclear Information System (INIS)

Horley, E.C.; Smith, H.A.

1996-01-01

Interactive multimedia training is rapidly becoming a popular and highly effective medium for learning. An interactive CD based training module on the Active Well Coincidence counter is being developed for on-site training at nuclear facility, including foreign facilities. The training module incorporates interactive text, graphics and video that demonstrate the operating principles, and the use and set-up of the instrument. The user is in control of the pace of learning and of the directions taken to acquire information based on personal need. By being in control, the user stays highly motivated. A mix of visuals (text and graphics), audio clips (in different languages), and video (with audio) clips also keeps the interest level high. Skill reviews and evaluations can be incorporated into the training to provide feedback to the student. In addition, general background information is provided on gamma and neutron based MC and A measurements. This material serves as a condensed MC and A encyclopedia. By supplying an interactive CD with an NDA instrument, nuclear facilities will have greater assurance operators are properly trained in the set-up and operation of the NDA-equipment

The next generation CdTe technology- Substrate foil based solar cells

Energy Technology Data Exchange (ETDEWEB)

Ferekides, Chris [Univ. of South Florida, Tampa, FL (United States)

2017-03-22

The main objective of this project was the development of one of the most promising Photovoltaic (PV) materials CdTe into a versatile, cost effective, and high throughput technology, by demonstrating substrate devices on foil substrates using high throughput fabrication conditions. The typical CdTe cell is of the superstrate configuration where the solar cell is fabricated on a glass superstrate by the sequential deposition of a TCO, n-type heterojunction partner, p-CdTe absorber, and back contact. Large glass modules are heavy and present significant challenges during manufacturing (uniform heating, etc.). If a substrate CdTe cell could be developed (the main goal of this project) a roll-to-toll high throughput technology could be developed.

Phenotyping and Target Expression Profiling of CD34+/CD38− and CD34+/CD38+ Stem- and Progenitor cells in Acute Lymphoblastic Leukemia

Directory of Open Access Journals (Sweden)

Katharina Blatt

2018-06-01

Full Text Available Leukemic stem cells (LSCs are an emerging target of curative anti-leukemia therapy. In acute lymphoblastic leukemia (ALL, LSCs frequently express CD34 and often lack CD38. However, little is known about markers and targets expressed in ALL LSCs. We have examined marker- and target expression profiles in CD34+/CD38− LSCs in patients with Ph+ ALL (n = 22 and Ph− ALL (n = 27 by multi-color flow cytometry and qPCR. ALL LSCs expressed CD19 (B4, CD44 (Pgp-1, CD123 (IL-3RA, and CD184 (CXCR4 in all patients tested. Moreover, in various subgroups of patients, LSCs also displayed CD20 (MS4A1 (10/41 = 24%, CD22 (12/20 = 60%, CD33 (Siglec-3 (20/48 = 42%, CD52 (CAMPATH-1 (17/40 = 43%, IL-1RAP (13/29 = 45%, and/or CD135 (FLT3 (4/20 = 20%. CD25 (IL-2RA and CD26 (DPPIV were expressed on LSCs in Ph+ ALL exhibiting BCR/ABL1p210, whereas in Ph+ ALL with BCR/ABL1p190, LSCs variably expressed CD25 but did not express CD26. In Ph− ALL, CD34+/CD38− LSCs expressed IL-1RAP in 6/18 patients (33%, but did not express CD25 or CD26. Normal stem cells stained negative for CD25, CD26 and IL-1RAP, and expressed only low amounts of CD52. In xenotransplantation experiments, CD34+/CD38− and CD34+/CD38+ cells engrafted NSG mice after 12–20 weeks, and targeting with antibodies against CD33 and CD52 resulted in reduced engraftment. Together, LSCs in Ph+ and Ph− ALL display unique marker- and target expression profiles. In Ph+ ALL with BCR/ABL1p210, the LSC-phenotype closely resembles the marker-profile of CD34+/CD38− LSCs in chronic myeloid leukemia, confirming the close biologic relationship of these neoplasms. Targeting of LSCs with specific antibodies or related immunotherapies may facilitate LSC eradication in ALL.

The impact of multimedia on teaching tropical medicine

Directory of Open Access Journals (Sweden)

M. F. Sarmento e Souza

2004-01-01

Full Text Available This study evaluated the impact of multimedia in the information transfer of subjects specific to Tropical Diseases - Tetanus and Snake Envenoming. We evaluated the autonomous learning process of 76 fourth-year medical students at Botucatu School of Medicine of UNESP, using printed matter, video, and CD-ROM. The students were submitted to a specific test, which was repeated approximately one week later. They were divided into groups and received a kit containing a textbook, a video, and a CD-ROM. These materials were used for out-of-class study. Before the second test, the students gave a seminar,where they discussed and resolved their doubts with their professor. The results of the first test showed averagesbetween 4.27±1.41 and 6.41±1.61. The second test, given after the seminar, presented averages that increased to 8.41±0.76 and 9.52±0.42, significance a = 5%. At the end of the course, the students answered a questionnaire, which evaluated the material quality and acquired knowledge. The students concluded that multimedia was a more efficient and quick means for knowledge building than traditional teaching materials. They said that the active participation and interactivity with the CD-ROM were the major differences. The authors continue to study the associated use of printed matter, video, and CD-ROM as a faster alternative to the traditional method of information transfer, which may be of help in the knowledge building process in medical education.

Fluorescence biosensor based on CdTe quantum dots for specific detection of H5N1 avian influenza virus

Science.gov (United States)

Hoa Nguyen, Thi; Dieu Thuy Ung, Thi; Hien Vu, Thi; Tran, Thi Kim Chi; Quyen Dong, Van; Khang Dinh, Duy; Liem Nguyen, Quang

2012-09-01

This report highlights the fabrication of fluorescence biosensors based on CdTe quantum dots (QDs) for specific detection of H5N1 avian influenza virus. The core biosensor was composed of (i) the highly luminescent CdTe/CdS QDs, (ii) chromatophores extracted from bacteria Rhodospirillum rubrum, and (iii) the antibody of β-subunit. This core part was linked to the peripheral part of the biosensor via a biotin-streptavidin-biotin bridge and finally connected to the H5N1 antibody to make it ready for detecting H5N1 avian influenza virus. Detailed studies of each constituent were performed showing the image of QDs-labeled chromatophores under optical microscope, proper photoluminescence (PL) spectra of CdTe/CdS QDs, chromatophores and the H5N1 avian influenza viruses.

In situ identification of CD44+/CD24- cancer cells in primary human breast carcinomas.

Directory of Open Access Journals (Sweden)

Giuseppe Perrone

Full Text Available Breast cancer cells with the CD44+/CD24- phenotype have been reported to be tumourigenic due to their enhanced capacity for cancer development and their self-renewal potential. The identification of human tumourigenic breast cancer cells in surgical samples has recently received increased attention due to the implications for prognosis and treatment, although limitations exist in the interpretation of these studies. To better identify the CD44+/CD24- cells in routine surgical specimens, 56 primary breast carcinoma cases were analysed by immunofluorescence and confocal microscopy, and the results were compared using flow cytometry analysis to correlate the amount and distribution of the CD44+/CD24- population with clinicopathological features. Using these methods, we showed that the breast carcinoma cells displayed four distinct sub-populations based on the expression pattern of CD44 and CD24. The CD44+/CD24- cells were found in 91% of breast tumours and constituted an average of 6.12% (range, 0.11%-21.23% of the tumour. A strong correlation was found between the percentage of CD44+/CD24- cells in primary tumours and distant metastasis development (p = 0.0001; in addition, there was an inverse significant association with ER and PGR status (p = 0.002 and p = 0.001, respectively. No relationship was evident with tumour size (T and regional lymph node (N status, differentiation grade, proliferative index or HER2 status. In a multivariate analysis, the percentage of CD44+/CD24- cancer cells was an independent factor related to metastasis development (p = 0.004. Our results indicate that confocal analysis of fluorescence-labelled breast cancer samples obtained at surgery is a reliable method to identify the CD44+/CD24- tumourigenic cell population, allowing for the stratification of breast cancer patients into two groups with substantially different relapse rates on the basis of CD44+/CD24- cell percentage.