WorldWideScience

Sample records for ccd-based image acquiring

  1. Evaluation of a CCD-based tissue imaging system

    International Nuclear Information System (INIS)

    A digital tissue imaging system based on a cooled charge coupled device (CCD) has been developed at the Physics Department of the Institute of Cancer Research. The system images low energy X-ray emissions and β particle emissions from a variety of isotopes, with a position resolution approaching 20μm and sensitivity approaching 100%. Because of the frame-by-frame composite way in which images are constructed, the dynamic range of the system is 16 bit, limited only by the microcomputer used to acquire and store the images. Images have been obtained of isotope distributions in tissue with radioactivity levels which were too low to be detected using conventional technology. Room temperature operation of the CCD in the inverted mode has been investigated

  2. The research and development of CCD-based slab continuous casting mold copper surface imaging system

    Science.gov (United States)

    Wang, Xingdong; Zhang, Liugang; Xie, Haihua; Long, Liaosha; Yu, Wenyong

    2011-11-01

    An imaging system for the continuous casting mold copper surface is researched and developed, to replace the on-line manual measuring method, which is used to checking Copper defects such as wearing, scratches and coating loss and other phenomena. Method: The imaging system proposes a special optical loop formed by three Mirrors, selects light source, CCD camera and lens type, designs mechanical transmission system and installation platform. Result: the optical loop and light source can insure imaging large-format object in narrow space. The CCD camera and lens determine the accuracy of horizontal scanning, and the mechanical transmission system ensures accuracy of the vertical scan. The installation platform supplies base and platform for the system. Conclusions: CCD-based copper surface imaging system effectively prevent defects such as missed measuring and low efficiency, etc. It can automatically and accurately shoot copper surface images on-line, and supply basis for image processing, defects identification and copper changing in the late.

  3. NIR area array CCD-based singlet oxygen luminescence imaging for photodynamic therapy

    International Nuclear Information System (INIS)

    In this work, a near-infrared CCD-based singlet oxygen luminescence two-dimensional imaging method is proposed to detect singlet oxygen by its 1270nm luminescence. Two-dimensional singlet oxygen images with its near-infrared luminescence during photosensitization could be obtained with a CCD integration time of 1s, without scanning. The data presented shows a linear relationship between the singlet oxygen luminescence intensity and sample concentration. This method provides a detection sensitivity of 0.00189mg/ml (Hematoporphyrin monomethyl Ether dissolved in ethanol) and a spatial resolution better than 100μm. We applied this method in vivo to demonstrate its potential in monitoring photodynamic therapy.

  4. A pnCCD-based, fast direct single electron imaging camera for TEM and STEM

    International Nuclear Information System (INIS)

    We report on a new camera that is based on a pnCCD sensor for applications in scanning transmission electron microscopy. Emerging new microscopy techniques demand improved detectors with regards to readout rate, sensitivity and radiation hardness, especially in scanning mode. The pnCCD is a 2D imaging sensor that meets these requirements. Its intrinsic radiation hardness permits direct detection of electrons. The pnCCD is read out at a rate of 1,150 frames per second with an image area of 264 x 264 pixel. In binning or windowing modes, the readout rate is increased almost linearly, for example to 4000 frames per second at 4× binning (264 x 66 pixel). Single electrons with energies from 300 keV down to 5 keV can be distinguished due to the high sensitivity of the detector. Three applications in scanning transmission electron microscopy are highlighted to demonstrate that the pnCCD satisfies experimental requirements, especially fast recording of 2D images. In the first application, 65536 2D diffraction patterns were recorded in 70 s. STEM images corresponding to intensities of various diffraction peaks were reconstructed. For the second application, the microscope was operated in a Lorentz-like mode. Magnetic domains were imaged in an area of 256 x 256 sample points in less than 37 seconds for a total of 65536 images each with 264 x 132 pixels. Due to information provided by the two-dimensional images, not only the amplitude but also the direction of the magnetic field could be determined. In the third application, millisecond images of a semiconductor nanostructure were recorded to determine the lattice strain in the sample. A speed-up in measurement time by a factor of 200 could be achieved compared to a previously used camera system

  5. A pnCCD-based, fast direct single electron imaging camera for TEM and STEM

    Science.gov (United States)

    Ryll, H.; Simson, M.; Hartmann, R.; Holl, P.; Huth, M.; Ihle, S.; Kondo, Y.; Kotula, P.; Liebel, A.; Müller-Caspary, K.; Rosenauer, A.; Sagawa, R.; Schmidt, J.; Soltau, H.; Strüder, L.

    2016-04-01

    We report on a new camera that is based on a pnCCD sensor for applications in scanning transmission electron microscopy. Emerging new microscopy techniques demand improved detectors with regards to readout rate, sensitivity and radiation hardness, especially in scanning mode. The pnCCD is a 2D imaging sensor that meets these requirements. Its intrinsic radiation hardness permits direct detection of electrons. The pnCCD is read out at a rate of 1,150 frames per second with an image area of 264 x 264 pixel. In binning or windowing modes, the readout rate is increased almost linearly, for example to 4000 frames per second at 4× binning (264 x 66 pixel). Single electrons with energies from 300 keV down to 5 keV can be distinguished due to the high sensitivity of the detector. Three applications in scanning transmission electron microscopy are highlighted to demonstrate that the pnCCD satisfies experimental requirements, especially fast recording of 2D images. In the first application, 65536 2D diffraction patterns were recorded in 70 s. STEM images corresponding to intensities of various diffraction peaks were reconstructed. For the second application, the microscope was operated in a Lorentz-like mode. Magnetic domains were imaged in an area of 256 x 256 sample points in less than 37 seconds for a total of 65536 images each with 264 x 132 pixels. Due to information provided by the two-dimensional images, not only the amplitude but also the direction of the magnetic field could be determined. In the third application, millisecond images of a semiconductor nanostructure were recorded to determine the lattice strain in the sample. A speed-up in measurement time by a factor of 200 could be achieved compared to a previously used camera system.

  6. Fast neutron fields imaging with a CCD-based luminescent detector

    International Nuclear Information System (INIS)

    The paper considers some questions concerned with the development of an imaging system based on a CCD-detector for visualising fast neutron fields. From those the most important are: development of fast neutron screens, detector resistance to irradiation fields, and feasibility of fast neutron radiography and tomography at various neutron sources

  7. Fast neutron fields imaging with a CCD-based luminescent detector

    CERN Document Server

    Mikerov, V

    1999-01-01

    The paper considers some questions concerned with the development of an imaging system based on a CCD-detector for visualising fast neutron fields. From those the most important are: development of fast neutron screens, detector resistance to irradiation fields, and feasibility of fast neutron radiography and tomography at various neutron sources.

  8. Use of a speckle reduction technique to improve the reconstruction image quality of CCD-based optical computed tomography scanner

    International Nuclear Information System (INIS)

    This study proposed a speckle reduction technique (SRT) that employs a rotating diffuser in the parallel beam optical computed tomography (CT). Results showed that the mean and standard deviation of the gray level are 89.79±4.53 and 89.16±2.88 for reconstruction images without SRT and with SRT, respectively. The proposed SRT effectively removed ring artifacts. In addition, two image processing techniques, namely, the mean and Wiener filters, were also used to improve the reconstructed images. The image processing technique alone effectively reduced ring artifacts, but some fluctuations were still observed in the line profiles of the reconstructed images. Results proved that the proposed SRT is a simple method that is easily implemented to improve image quality for parallel beam optical CT. The combination of SRT and image filters was suggested to achieve the best image reconstruction quality through the full removal of ring artifacts. - Highlights: • Speckle reduction technique is effective to remove ring artifacts. • The fluctuation in reconstruction image can be reduced using speckle reduction technique. • The image processing technique can reduce the ring artifacts effectively, but few fluctuations can still be observed in line profiles. • The combination speckle reduction technique and image filters can achieve the best quality of reconstruction image

  9. Real-time detection of DNA hybridization on microarray using a CCD-based imaging system equipped with a rotated microlens array disk.

    Science.gov (United States)

    Mogi, Takeyuki; Hatakeyama, Keiichi; Taguchi, Tomoyuki; Wake, Hitoshi; Tanaami, Takeo; Hosokawa, Masahito; Tanaka, Tsuyoshi; Matsunaga, Tadashi

    2011-01-15

    This work describes a novel charge-coupled device (CCD)-based imaging system (MB Biochip Reader™) for real-time detection of DNA hybridization to DNA microarrays. The MB Biochip Reader™ consisted of a laser light source (532 nm), a microlens array for generation of a multi-beam laser, and a CCD for 2-D signal imaging. The MB Biochip Reader™ with a rotated microlens array, allowed large-field imaging (6.2 mm × 7.6 mm with 6.45 μm resolution) with fast time-resolution at 0.2 s without speckle noise. Furthermore, real-time detection of DNA hybridization, which is sufficient to obtain accurate data from tens of thousands of array element per field, was successfully performed without the need for laser scanning. The performance of the MB Biochip Reader™ for DNA microarray imaging was similar to the commercially available photomultiplier tube (PMT)-based microarray scanner, ScanArray Lite. The system potentially could be applied toward real-time analysis in many other fluorescent techniques in addition to real-time DNA microarray analysis. PMID:20951567

  10. CCD-based thermoreflectance microscopy: principles and applications

    International Nuclear Information System (INIS)

    CCD-based thermoreflectance microscopy has emerged as a high resolution, non-contact imaging technique for thermal profiling and performance and reliability analysis of numerous electronic and optoelectronic devices at the micro-scale. This thermography technique, which is based on measuring the relative change in reflectivity of the device surface as a function of change in temperature, provides high-resolution thermal images that are useful for hot spot detection and failure analysis, mapping of temperature distribution, measurement of thermal transient, optical characterization of photonic devices and measurement of thermal conductivity in thin films. In this paper we review the basic physical principle behind thermoreflectance as a thermography tool, discuss the experimental setup, resolutions achieved, signal processing procedures and calibration techniques, and review the current applications of CCD-based thermoreflectance microscopy in various devices. (topical review)

  11. CCD-based optical CT scanning of highly attenuating phantoms

    Energy Technology Data Exchange (ETDEWEB)

    Al-Nowais, Shamsa [Department of Physics, University of Surrey, Guildford (United Kingdom); Doran, Simon J [CRUK Clinical MR Research Group, Institute of Cancer Research, Sutton (United Kingdom)], E-mail: Simon.Doran@icr.ac.uk

    2009-05-01

    The introduction of optical computed tomography (optical-CT) offers economic and easy to use 3-D optical readout for gel dosimeters. However, previous authors have noted some challenges regarding the accuracy of such imaging techniques at high values of optical density. In this paper, we take a closer look at the 'cupping' artefact evident in both light-scattering polymer systems and highly light absorbing phantoms using our CCD-based optical scanner. In addition, a technique is implemented whereby the maximum measurable optical absorbance is extended to correct for any errors that may have occurred in the estimated value of the dark current or ambient light reaching the detector. The results indicate that for absorbance values up to 2.0, the optical scanner results have good accuracy, whereas this is not the case at high absorbance values for reasons yet to be explained.

  12. Radionuclide brain imaging in acquired immunodeficiency syndrome (AIDS)

    International Nuclear Information System (INIS)

    Infection with the Human Immunodeficiency Virus type 1 (HIV-1) may produce a variety of central nervous system (CNS) symptoms and signs. CNS involvement in patients with the Acquired Immunodeficiency Syndrome (AIDS) includes AIDS dementia complex or HIV-1 associated cognitive/motor complex (widely known as HIV encephalopathy), progressive multifocal leucoencephalopathy (PML), opportunistic infections such as Toxoplasma gondii, TB, Cryptococcus and infiltration by non-Hodgkin's B cell lymphoma. High resolution structural imaging investigations, either X-ray Computed Tomography (CT scan) or Magnetic Resonance Imaging (MRI) have contributed to the understanding and definition of cerebral damage caused by HIV encephalopathy. Atrophy and mainly high signal scattered white matter abnormalities are commonly seen with MRI. PML produces focal white matter high signal abnormalities due to multiple foci of demyelination. However, using structural imaging techniques there are no reliable parameters to distinguish focal lesions due to opportunistic infection (Toxoplasma gondii abscess) from neoplasm (lymphoma infiltration). It is studied the use of radionuclide brain imaging techniques in the investigation of HIV infected patients. Brain perfusion Single Photon Emission Tomography (SPET), neuroreceptor and Positron Emission Tomography (PET) studies are reviewed. Greater emphasis is put on the potential of some radiopharmaceuticals, considered to be brain tumour markers, to distinguish intracerebral lymphoma infiltration from Toxoplasma infection. SPET with 201Tl using quantification (tumour to non-tumour radioactivity ratios) appears a very promising technique to identify intracerebral lymphoma

  13. Radionuclide brain imaging in acquired immunodeficiency syndrome (AIDS)

    Energy Technology Data Exchange (ETDEWEB)

    Costa, D.C.; Gacinovic, S.; Miller, R.F. [London University College Medical School, Middlesex Hospital, London (United Kingdom)

    1995-09-01

    Infection with the Human Immunodeficiency Virus type 1 (HIV-1) may produce a variety of central nervous system (CNS) symptoms and signs. CNS involvement in patients with the Acquired Immunodeficiency Syndrome (AIDS) includes AIDS dementia complex or HIV-1 associated cognitive/motor complex (widely known as HIV encephalopathy), progressive multifocal leucoencephalopathy (PML), opportunistic infections such as Toxoplasma gondii, TB, Cryptococcus and infiltration by non-Hodgkin`s B cell lymphoma. High resolution structural imaging investigations, either X-ray Computed Tomography (CT scan) or Magnetic Resonance Imaging (MRI) have contributed to the understanding and definition of cerebral damage caused by HIV encephalopathy. Atrophy and mainly high signal scattered white matter abnormalities are commonly seen with MRI. PML produces focal white matter high signal abnormalities due to multiple foci of demyelination. However, using structural imaging techniques there are no reliable parameters to distinguish focal lesions due to opportunistic infection (Toxoplasma gondii abscess) from neoplasm (lymphoma infiltration). It is studied the use of radionuclide brain imaging techniques in the investigation of HIV infected patients. Brain perfusion Single Photon Emission Tomography (SPET), neuroreceptor and Positron Emission Tomography (PET) studies are reviewed. Greater emphasis is put on the potential of some radiopharmaceuticals, considered to be brain tumour markers, to distinguish intracerebral lymphoma infiltration from Toxoplasma infection. SPET with {sup 201}Tl using quantification (tumour to non-tumour radioactivity ratios) appears a very promising technique to identify intracerebral lymphoma.

  14. Self-acquired patient images: the promises and the pitfalls.

    Science.gov (United States)

    Damanpour, Shadi; Srivastava, Divya; Nijhawan, Rajiv I

    2016-03-01

    Self-acquired patient images, also known as selfies, are increasingly utilized in the practice of dermatology; however, research on their utility is somewhat limited. While the implementation of selfies has yet to be universally accepted, their role in triage appears to be especially useful. The potential for reducing office wait times, expediting referrals, and providing dermatologic services to patients with limited access to care is promising. In addition, as technology advances, the number of smartphone applications related to dermatology that are available to the general public has risen exponentially. With appropriate standardization, regulation, and confidentiality measures, these tools can be feasible adjuncts in clinical practice, dermatologic surgery, and teledermatology. Selfies likely will have a large role in dermatologic practice and delivery in the future. PMID:26963112

  15. An image-guided tool to prevent hospital acquired infections

    Science.gov (United States)

    Nagy, Melinda; Szilágyi, László; Lehotsky, Ákos; Haidegger, Tamás; Benyó, Balázs

    2011-03-01

    Hospital Acquired Infections (HAI) represent the fourth leading cause of death in the United States, and claims hundreds of thousands of lives annually in the rest of the world. This paper presents a novel low-cost mobile device|called Stery-Hand|that helps to avoid HAI by improving hand hygiene control through providing an objective evaluation of the quality of hand washing. The use of the system is intuitive: having performed hand washing with a soap mixed with UV re ective powder, the skin appears brighter in UV illumination on the disinfected surfaces. Washed hands are inserted into the Stery-Hand box, where a digital image is taken under UV lighting. Automated image processing algorithms are employed in three steps to evaluate the quality of hand washing. First, the contour of the hand is extracted in order to distinguish the hand from the background. Next, a semi-supervised clustering algorithm classies the pixels of the hand into three groups, corresponding to clean, partially clean and dirty areas. The clustering algorithm is derived from the histogram-based quick fuzzy c-means approach, using a priori information extracted from reference images, evaluated by experts. Finally, the identied areas are adjusted to suppress shading eects, and quantied in order to give a verdict on hand disinfection quality. The proposed methodology was validated through tests using hundreds of images recorded in our laboratory. The proposed system was found robust and accurate, producing correct estimation for over 98% of the test cases. Stery-Hand may be employed in general practice, and it may also serve educational purposes.

  16. Aerial Image over Flint Hills National Wildlife Refuge, Acquired on March 22, 1950 (Frame 1686)

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Georeferenced image, acquired on March 22, 1950, over a portion of the Flint Hills National Wildlife Refuge. Image covers the central and western portions of the...

  17. Aerial Image over Flint Hills National Wildlife Refuge, Acquired on March 22, 1950 (Frame 1656)

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Georeferenced image, acquired on March 22, 1950, over a portion of the Flint Hills National Wildlife Refuge. Image covers the eastern portion of the refuge...

  18. Aerial Image over Flint Hills National Wildlife Refuge, Acquired on March 22, 1950 (Frame 1685)

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Georeferenced image, acquired on March 22, 1950, over a portion of the Flint Hills National Wildlife Refuge. Image covers the central portion of the refuge...

  19. Aerial Image over Flint Hills National Wildlife Refuge, Acquired on March 22, 1950 (Frame 1655)

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Georeferenced image, acquired on March 22, 1950, over a portion of the Flint Hills National Wildlife Refuge. Image covers the eastern portion of the refuge...

  20. Aerial Image over Flint Hills National Wildlife Refuge, Acquired on April 14, 1948 (Frame 1154)

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Georeferenced image, acquired on April 14, 1948, over a portion of the Flint Hills National Wildlife Refuge. Image covers the eastern portion of the refuge...

  1. Aerial Image over Flint Hills National Wildlife Refuge, Acquired on April 14, 1948 (Frame 1155)

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Georeferenced image, acquired on April 14, 1948, over a portion of the Flint Hills National Wildlife Refuge. Image covers the eastern portion of the refuge...

  2. Aerial Image over Ouray National Wildlife Refuge, Acquired on August 27, 1965 (Frame 131)

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Georeferenced image, acquired on August 27, 1965 over a portion of the Ouray National Wildlife Refuge. Image covers the northern portion of the refuge including...

  3. High-sensitivity CCD-based x-ray detector

    International Nuclear Information System (INIS)

    The detector is designed for imaging measurements requiring relatively high sensitivity and high spatial resolution. The detector can discriminate single X-ray photons, yet has the wide dynamic range (∼10000:1) associated with integrating detectors. A GdO2S2 phosphor screen converts the incoming X-ray image into an optical image. The optical image is coupled (without demagnification) to the CCD image sensor using a fiber optic faceplate. The CCD (Philips Semiconductors) has an area of 4.9 x 8.6 cm with 4000 x 7000 12 μm pixels. A single 12 keV X-ray photon produces a signal of 100 e-. With 2 x 2 pixel binning, the total noise per 24 μm pixel in a 100 s image is ∼30 e-, the detective quantum efficiency is >0.6 at 1 X-ray photon per pixel, and the full image can be read out in <4 s. The spatial resolution is 50 μm. The CCD readout system is fully computer-controlled, allowing flexible operation in time-resolved experiments. The detector has been characterized using visible-light images, X-ray images and time-resolved muscle diffraction measurements.

  4. Methods for identification of images acquired with digital cameras

    Science.gov (United States)

    Geradts, Zeno J.; Bijhold, Jurrien; Kieft, Martijn; Kurosawa, Kenji; Kuroki, Kenro; Saitoh, Naoki

    2001-02-01

    From the court we were asked whether it is possible to determine if an image has been made with a specific digital camera. This question has to be answered in child pornography cases, where evidence is needed that a certain picture has been made with a specific camera. We have looked into different methods of examining the cameras to determine if a specific image has been made with a camera: defects in CCDs, file formats that are used, noise introduced by the pixel arrays and watermarking in images used by the camera manufacturer.

  5. Building Extraction from DSM Acquired by Airborne 3D Image

    Institute of Scientific and Technical Information of China (English)

    YOU Hongjian; LI Shukai

    2003-01-01

    Segmentation and edge regulation are studied deeply to extract buildings from DSM data produced in this paper. Building segmentation is the first step to extract buildings, and a new segmentation method-adaptive iterative segmentation considering ratio mean square-is proposed to extract the contour of buildings effectively. A sub-image (such as 50× 50 pixels )of the image is processed in sequence,the average gray level and its ratio mean square are calculated first, then threshold of the sub-image is selected by using iterative threshold segmentation. The current pixel is segmented according to the threshold, the aver-age gray level and the ratio mean square of the sub-image. The edge points of the building are grouped according to the azimuth of neighbor points, and then the optimal azimuth of the points that belong to the same group can be calculated by using line interpolation.

  6. Image fusion based on images of SPECT and CT modalities acquired in separated scanners

    International Nuclear Information System (INIS)

    Full text: Developing countries have several limitations to acquire the new high cost hybrid devices such as SPECT-CT or PET-CT for combined clinical diagnosis, due to the very limited budget most hospitals currently have. However, the information that combined diagnostic modalities offer to physicians is very helpful in determining the exact site of radiopharmaceutical concentration both in physiological or pathological situations, leading to a more accurate treatment for patients. Moreover, the information obtained from the electronic density from X rays on CT images gives the information that radiologists need for morphologic diagnosis. In our experience combined imaging modalities (metabolic and structural) gives usually more information that the sum of individual modalities. This opinion is based on performing co-registered PET-CT imaging over thousands of patients. In this paper, we propose an Acquisition Protocol to obtain SPECT and CT images from already existent dedicated devices in a hospital, in an appropriate condition allowing to be used for co-registration and later on, fusion and interpretation. Since the patient must move from one scanner to the other, we set the following conditions in both scanners: - Planar bed, which is accomplished by putting an insert over the conventional bed. This append must have a very low attenuation correction, such as MDF, wood, polycarbonate, or glass fibber, strong enough to support the patient weight. -Head and neck support, to fix head and neck, depending on the region studied. - Thermoplastic mask fixed to the head and neck support, in the same way that is used for radiotherapy planning. -Angle guide to place the patient's head in the most accurate position. This setting is also used in radiotherapy. - Belts to properly fix arms and legs. -Pillows, cushions and blankets to assure patients comfort, avoiding the risk of involuntary movements due to cramps and pain. Depending on the clinical case under study, patient

  7. Series of Aerial Images over Flint Hills National Wildlife Refuge, Acquired on November 20, 1969.

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This data set includes 19 Georeferenced images, acquired on November 20, 1969, over Flint Hills National Wildlife Refuge. The frames were downloaded from Earth...

  8. Series of aerial images over Bear River Migratory Bird Refuge, acquired in 1937

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This dataset includes 40 georeferenced images, acquired on September 25th, October 12th-13th, November 10th and December 1st, 1937 over portions of Bear River...

  9. Lensless CCD-based fluorometer using a micromachined optical Soller collimator

    NARCIS (Netherlands)

    Balsam, Joshua; Ossandon, Miguel; Kostov, Yordan; Bruck, Hugh Alan; Rasooly, Avraham

    2011-01-01

    In this paper, we describe a simple charge-coupled device (CCD) based lensless fluorometer with sensitivity in the range of current ELISA plate readers. In our lensfree fluorometer, a multi-wavelength LED light source was used for fluorophore excitation. To collimate the light, we developed a simple

  10. RF Device for Acquiring Images of the Human Body

    Science.gov (United States)

    Gaier, Todd C.; McGrath, William R.

    2010-01-01

    A safe, non-invasive method for forming images through clothing of large groups of people, in order to search for concealed weapons either made of metal or not, has been developed. A millimeter wavelength scanner designed in a unique, ring-shaped configuration can obtain a full 360 image of the body with a resolution of less than a millimeter in only a few seconds. Millimeter waves readily penetrate normal clothing, but are highly reflected by the human body and concealed objects. Millimeter wave signals are nonionizing and are harmless to human tissues when used at low power levels. The imager (see figure) consists of a thin base that supports a small-diameter vertical post about 7 ft (=2.13 m) tall. Attached to the post is a square-shaped ring 2 in. (=5 cm) wide and 3 ft (=91 cm) on a side. The ring is oriented horizontally, and is supported halfway along one side by a connection to a linear bearing on the vertical post. A planar RF circuit board is mounted to the inside of each side of the ring. Each circuit board contains an array of 30 receivers, one transmitter, and digitization electronics. Each array element has a printed-circuit patch antenna coupled to a pair of mixers by a 90 coupler. The mixers receive a reference local oscillator signal to a subharmonic of the transmitter frequency. A single local oscillator line feeds all 30 receivers on the board. The resulting MHz IF signals are amplified and carried to the edge of the board where they are demodulated and digitized. The transmitted signal is derived from the local oscillator at a frequency offset determined by a crystal oscillator. One antenna centrally located on each side of the square ring provides the source illumination power. The total transmitted power is less than 100 mW, resulting in an exposure level that is completely safe to humans. The output signals from all four circuit boards are fed via serial connection to a data processing computer. The computer processes the approximately 1-MB

  11. Hounsfield unit recovery in clinical cone beam CT images of the thorax acquired for image guided radiation therapy

    DEFF Research Database (Denmark)

    Slot Thing, Rune; Bernchou, Uffe; Mainegra-Hing, Ernesto;

    2016-01-01

    A comprehensive artefact correction method for clinical cone beam CT (CBCT) images acquired for image guided radiation therapy (IGRT) on a commercial system is presented. The method is demonstrated to reduce artefacts and recover CT-like Hounsfield units (HU) in reconstructed CBCT images of five ...

  12. LED characterization for development of on-board calibration unit of CCD-based advanced wide-field sensor camera of Resourcesat-2A

    Science.gov (United States)

    Chatterjee, Abhijit; Verma, Anurag

    2016-05-01

    The Advanced Wide Field Sensor (AWiFS) camera caters to high temporal resolution requirement of Resourcesat-2A mission with repeativity of 5 days. The AWiFS camera consists of four spectral bands, three in the visible and near IR and one in the short wave infrared. The imaging concept in VNIR bands is based on push broom scanning that uses linear array silicon charge coupled device (CCD) based Focal Plane Array (FPA). On-Board Calibration unit for these CCD based FPAs is used to monitor any degradation in FPA during entire mission life. Four LEDs are operated in constant current mode and 16 different light intensity levels are generated by electronically changing exposure of CCD throughout the calibration cycle. This paper describes experimental setup and characterization results of various flight model visible LEDs (λP=650nm) for development of On-Board Calibration unit of Advanced Wide Field Sensor (AWiFS) camera of RESOURCESAT-2A. Various LED configurations have been studied to meet dynamic range coverage of 6000 pixels silicon CCD based focal plane array from 20% to 60% of saturation during night pass of the satellite to identify degradation of detector elements. The paper also explains comparison of simulation and experimental results of CCD output profile at different LED combinations in constant current mode.

  13. Imaging of community-acquired pneumonia: Roles of imaging examinations, imaging diagnosis of specific pathogens and discrimination from noninfectious diseases

    Institute of Scientific and Technical Information of China (English)

    Atsushi; Nambu; Katsura; Ozawa; Noriko; Kobayashi; Masao; Tago

    2014-01-01

    This article reviews roles of imaging examinations in the management of community-acquired pneumonia(CAP), imaging diagnosis of specific CAP and discrimination between CAP and noninfectious diseases. Chest radiography is usually enough to confirm the diagnosis of CAP, whereas computed tomography is required to suggest specific pathogens and to discriminate from noninfectious diseases. Mycoplasma pneumoniae pneumonia, tuberculosis, Pneumocystis jirovecii pneumonia and some cases of viral pneumonia sometimes show specific imaging findings. Peribronchial nodules, especially tree-in-bud appearance, are fairly specific for infection. Evidences of organization, such as concavity of the opacities, traction bronchiectasis, visualization of air bronchograms over the entire length of the bronchi, or mild parenchymal distortion are suggestive of organizing pneumonia. We will introduce tips to effectively make use of imaging examinations in the management of CAP.

  14. Hounsfield unit recovery in clinical cone beam CT images of the thorax acquired for image guided radiation therapy

    Science.gov (United States)

    Slot Thing, Rune; Bernchou, Uffe; Mainegra-Hing, Ernesto; Hansen, Olfred; Brink, Carsten

    2016-08-01

    A comprehensive artefact correction method for clinical cone beam CT (CBCT) images acquired for image guided radiation therapy (IGRT) on a commercial system is presented. The method is demonstrated to reduce artefacts and recover CT-like Hounsfield units (HU) in reconstructed CBCT images of five lung cancer patients. Projection image based artefact corrections of image lag, detector scatter, body scatter and beam hardening are described and applied to CBCT images of five lung cancer patients. Image quality is evaluated through visual appearance of the reconstructed images, HU-correspondence with the planning CT images, and total volume HU error. Artefacts are reduced and CT-like HUs are recovered in the artefact corrected CBCT images. Visual inspection confirms that artefacts are indeed suppressed by the proposed method, and the HU root mean square difference between reconstructed CBCTs and the reference CT images are reduced by 31% when using the artefact corrections compared to the standard clinical CBCT reconstruction. A versatile artefact correction method for clinical CBCT images acquired for IGRT has been developed. HU values are recovered in the corrected CBCT images. The proposed method relies on post processing of clinical projection images, and does not require patient specific optimisation. It is thus a powerful tool for image quality improvement of large numbers of CBCT images.

  15. CT and MR imaging of acquired abnormalities of the inner ear and cerebellopontine angle

    International Nuclear Information System (INIS)

    Introduction: Several entities of acquired lesions may affect the inner ear and cerebellopontine angle. The imaging of these lesions depends on the clinical history, and should be adapted to the lesion searched for and suspected by the otolaryngologist. In this paper, the modality of CT and MR imaging which is suited to delineate the acquired lesions of this region will be presented. Materials and methods: CT and/or MR imaging of the inner ear and cerebellopontine angle was performed in all cases in which an acquired lesion of this region was suspected by the otolaryngologist. CT was performed in the axial and coronal plane with the use of a high-resolution bone-window-level-setting. MRI was performed in the axial plane using high-resolution 3D T2-weighted fast spin echo sequences and 3D T1-weighted gradient echo sequences before and after the i.v. application of gadopentate dimeglumine. The obtained images were evaluated for the depiction of the acquired lesions. Results: CT best depicted osseous lesions such as traumatic affections or lesions leading to ossification of the inner ear. Tumorous lesions were delineated in those cases in which they yielded to bony changes. Inflammatory or tumorous lesions not yielding to bony changes or intralabyrintine calicifications were not depicted. MRI delineated very well all lesions leading to soft tissue changes, and moderately depicted traumatic changes yielding to less severe fractures affecting the investigated region. Conclusion: CT and MR imaging are suited differently to delineate the acquired lesions of the inner ear and cerebellopontine angle. CT is excellently suited to depict osseous lesions, while MRI is excellently suited to delineate lesions affecting the soft tissue structures. These two imaging modalities should be used depending on the clinical question, and are supposed to be complementary methods

  16. Precision Agriculture: Using Low-Cost Systems to Acquire Low-Altitude Images.

    Science.gov (United States)

    Ponti, Moacir; Chaves, Arthur A; Jorge, Fabio R; Costa, Gabriel B P; Colturato, Adimara; Branco, Kalinka R L J C

    2016-01-01

    Low cost remote sensing imagery has the potential to make precision farming feasible in developing countries. In this article, the authors describe image acquisition from eucalyptus, bean, and sugarcane crops acquired by low-cost and low-altitude systems. They use different approaches to handle low-altitude images in both the RGB and NIR (near-infrared) bands to estimate and quantify plantation areas. PMID:27514030

  17. Dynamic Linear Model Analysis of Optical Imaging Data Acquired from the Human Neocortex

    OpenAIRE

    Lavine, Michael; Haglund, Michael M.; Hochman, Daryl W.

    2011-01-01

    The amount of light absorbed and scattered by neocortical tissue is altered by neuronal activity. Imaging of intrinsic optical signals (ImIOS), a technique for mapping these activity-evoked optical changes with an imaging detector, has the potential to be useful for both clinical and experimental investigations of the human neocortex. However, its usefulness for human studies is currently limited because intraoperatively acquired ImIOS data is noisy. To improve the reliability and usefulness ...

  18. STRIPING NOISE REMOVAL OF IMAGES ACQUIRED BY CBERS 2 CCD CAMERA SENSOR

    Directory of Open Access Journals (Sweden)

    E. Amraei

    2014-10-01

    Full Text Available CCD Camera is a multi-spectral sensor that is carried by CBERS 2 satellite. Imaging technique in this sensor is push broom. In images acquired by the CCD Camera, some vertical striping noise can be seen. This is due to the detectors mismatch, inter detector variability, improper calibration of detectors and low signal-to-noise ratio. These noises are more profound in images acquired from the homogeneous surfaces, which are processed at level 2. However, the existence of these noises render the interpretation of the data and extracting information from these images difficult. In this work, spatial moment matching method is proposed to modify these images. In this method, the statistical moments such as mean and standard deviation of columns in each band are used to balance the statistical specifications of the detector array to those of reference values. After the removal of the noise, some periodic diagonal stripes remain in the image where their removal by using the aforementioned method seems impossible. Therefore, to omit them, frequency domain Butterworth notch filter was applied. Finally to evaluate the results, the image statistical moments such as the mean and standard deviation were deployed. The study proves the effectiveness of the method in noise removal.

  19. SU-E-J-186: Acquiring and Assessing Upright CBCT Images for Future Treatment Planning

    International Nuclear Information System (INIS)

    Purpose: To acquire upright CBCT images using the onboard imager of a Varian TrueBeam. An easy to implement upright imaging protocol could allow for widespread upright radiation therapy which would greatly benefit certain patients. These include thoracic cancer patients (because lung volume increases in a seated position) and patients who experience substantial discomfort during supine treatment. Methods: To acquire upright CBCT images, the gantry head remained stationary at 0 degrees with the KV imager arms extended to their lateral positions. Phantoms were placed upright at the end of the treatment couch. During a scan, the couch rotated from 270 to 90 degrees while continuous fluoroscopic projections were taken by the onboard imager. To extend the field-of-view, this sequence was performed twice: once with the KV detector longitudinally offset +14.5cm and once with it longitudinally offset −14.5cm. The resulting two image sets were stitched together before reconstruction. The imaging beam parameters were chosen to deliver a dose similar to that given during a simulation CT. Image quality was evaluated for spatial linearity, high and low contrast resolution, and HU linearity using CatPhan and anthropomorphic phantoms. A deformable registration technique was used to evaluate HU mapping from a simulation CT. Results: Spatial linearity and high contrast resolution were maintained in upright CBCT when compared to simulation CT. However, low contrast resolution and HU linearity degraded. Streak artifacts were caused by the limited 180 degree arc of the couch, and the stitching process created a sharp artifact at the center of the reconstruction. The deformable registration was robust in the HU mapping even with these artifacts and the loss of HU linearity. Conclusions: The image quality obtained from upright CBCT was sufficient for treatment planning. The success of this novel technique is an important step towards a future clinical protocol. This project was funded

  20. Estimating plant traits of grasslands from UAV-acquired hyperspectral images

    OpenAIRE

    Capolupo, Alessandra; Kooistra, Lammert; Berendonk, Clara; Boccia, Lorenzo; Suomalainen, Juha

    2015-01-01

    Grassland ecosystems cover around 40% of the entire Earth's surface. Therefore, it is necessary to guarantee good grassland management at field scale in order to improve its conservation and to achieve optimal growth. This study identified the most appropriate statistical strategy, between partial least squares regression (PLSR) and narrow vegetation indices, for estimating the structural and biochemical grassland traits from UAV-acquired hyperspectral images. Moreover, the influence of ferti...

  1. Estimating Plant Traits of Grasslands from UAV-Acquired Hyperspectral Images: A Comparison of Statistical Approaches

    OpenAIRE

    Alessandra Capolupo; Lammert Kooistra; Clara Berendonk; Lorenzo Boccia; Juha Suomalainen

    2015-01-01

    Grassland ecosystems cover around 40% of the entire Earth’s surface. Therefore, it is necessary to guarantee good grassland management at field scale in order to improve its conservation and to achieve optimal growth. This study identified the most appropriate statistical strategy, between partial least squares regression (PLSR) and narrow vegetation indices, for estimating the structural and biochemical grassland traits from UAV-acquired hyperspectral images. Moreover, the influence of ferti...

  2. Non-negative factor analysis supporting the interpretation of elemental distribution images acquired by XRF

    OpenAIRE

    Alfeld, Matthias; Wahabzada, Mirwaes; Bauckhage, Christian; Kersting, Kristian; Wellenreuther, Gerd; Falkenberg, Gerald

    2014-01-01

    Stacks of elemental distribution images acquired by XRF can be difficult to interpret, if they contain high degrees of redundancy and components differing in their quantitative but not qualitative elemental composition. Factor analysis, mainly in the form of Principal Component Analysis (PCA), has been used to reduce the level of redundancy and highlight correlations. PCA, however, does not yield physically meaningful representations as they often contain negative values. This limitation can ...

  3. Dynamic Linear Model Analysis of Optical Imaging Data Acquired from the Human Neocortex

    Science.gov (United States)

    Lavine, Michael; Haglund, Michael M.; Hochman, Daryl W.

    2011-01-01

    The amount of light absorbed and scattered by neocortical tissue is altered by neuronal activity. Imaging of intrinsic optical signals (ImIOS), a technique for mapping these activity-evoked optical changes with an imaging detector, has the potential to be useful for both clinical and experimental investigations of the human neocortex. However, its usefulness for human studies is currently limited because intraoperatively acquired ImIOS data is noisy. To improve the reliability and usefulness of ImIOS for human studies, it is desirable to find appropriate methods for the removal of noise artifacts and its statistical analysis. Here we develop a Bayesian, dynamic linear modeling approach that appears to address these problems. A dynamic linear model (DLM) was constructed that included cyclic components to model the heartbeat and respiration artifacts, and a local linear component to model the activity-evoked response. The robustness of the model was tested on a set of ImIOS data acquired from the exposed cortices of six human subjects illuminated with either 535 nm or 660 nm light. The DLM adequately reduced noise artifacts in these data while reliably preserving their activity-evoked optical responses. To demonstrate how these methods might be used for intraoperative neurosurgical mapping, optical data acquired from a single human subject during direct electrical stimulation of the cortex were quantitatively analyzed. This example showed that the DLM can be used to provide quantitative information about human ImIOS data that is not available through qualitative analysis alone. PMID:21640137

  4. Conductive resins improve charging and resolution of acquired images in electron microscopic volume imaging

    OpenAIRE

    Huy Bang Nguyen; Truc Quynh Thai; Sei Saitoh; Bao Wu; Yurika Saitoh; Satoshi Shimo; Hiroshi Fujitani; Hirohide Otobe; Nobuhiko Ohno

    2016-01-01

    Recent advances in serial block-face imaging using scanning electron microscopy (SEM) have enabled the rapid and efficient acquisition of 3-dimensional (3D) ultrastructural information from a large volume of biological specimens including brain tissues. However, volume imaging under SEM is often hampered by sample charging, and typically requires specific sample preparation to reduce charging and increase image contrast. In the present study, we introduced carbon-based conductive resins for 3...

  5. CT and MR imaging evaluation of the inherited and prenatally acquired migrational disorders of the brain

    International Nuclear Information System (INIS)

    The migrational disorders are a rare group of congenital malformations of the brain seen in children. They are primarily cortical and gray matter abnormalities. Forty patients, divided into two groups, were studied. In one group were patients with the classic migrational lesions of lissencephaly, pachygyria, schizencephaly, heterotopia, and polymicrogyria in which the underlying cause is genetic, chromosomal, or unknown. In the second group were patients with lesions caused by a prenatally acquired infection (toxoplasmosis or cytomegalic virus) or a metabolic abnormality. The CT and MR imaging findings in these two groups are discussed

  6. Image processing and classification procedures for analysis of sub-decimeter imagery acquired with an unmanned aircraft over arid rangelands

    Science.gov (United States)

    Using five centimeter resolution images acquired with an unmanned aircraft system (UAS), we developed and evaluated an image processing workflow that included the integration of resolution-appropriate field sampling, feature selection, object-based image analysis, and processing approaches for UAS i...

  7. A megavoltage scatter correction technique for cone-beam CT images acquired during VMAT delivery

    International Nuclear Information System (INIS)

    Kilovoltage cone-beam CT (kV CBCT) can be acquired during the delivery of volumetric modulated arc therapy (VMAT), in order to obtain an image of the patient during treatment. However, the quality of such CBCTs is degraded by megavoltage (MV) scatter from the treatment beam onto the imaging panel. The objective of this paper is to introduce a novel MV scatter correction method for simultaneous CBCT during VMAT, and to investigate its effectiveness when compared to other techniques. The correction requires the acquisition of a separate set of images taken during VMAT delivery, while the kV beam is off. These images—which contain only the MV scatter contribution on the imaging panel—are then used to correct the corresponding kV/MV projections. To test this method, CBCTs were taken of an image quality phantom during VMAT delivery and measurements of contrast to noise ratio were made. Additionally, the correction was applied to the datasets of three VMAT prostate patients, who also received simultaneous CBCTs. The clinical image quality was assessed using a validated scoring system, comparing standard CBCTs to the uncorrected simultaneous CBCTs and a variety of correction methods. Results show that the correction is able to recover some of the low and high-contrast signal to noise ratio lost due to MV scatter. From the patient study, the corrected CBCT scored significantly higher than the uncorrected images in terms of the ability to identify the boundary between the prostate and surrounding soft tissue. In summary, a simple MV scatter correction method has been developed and, using both phantom and patient data, is shown to improve the image quality of simultaneous CBCTs taken during VMAT delivery. (paper)

  8. CNN intelligent early warning for apple skin lesion image acquired by infrared video sensors

    Institute of Scientific and Technical Information of China (English)

    谭文学

    2016-01-01

    Video sensors and agricultural IoT ( internet of things) have been widely used in the informa-tionalized orchards.In order to realize intelligent-unattended early warning for disease-pest, this pa-per presents convolutional neural network ( CNN) early warning for apple skin lesion image, which is real-time acquired by infrared video sensor.More specifically, as to skin lesion image, a suite of processing methods is devised to simulate the disturbance of variable orientation and light condition which occurs in orchards.It designs a method to recognize apple pathologic images based on CNN, and formulates a self-adaptive momentum rule to update CNN parameters.For example, a series of experiments are carried out on the recognition of fruit lesion image of apple trees for early warning. The results demonstrate that compared with the shallow learning algorithms and other involved, well-known deep learning methods, the recognition accuracy of the proposal is up to 96.08%, with a fairly quick convergence, and it also presents satisfying smoothness and stableness after conver-gence.In addition, statistics on different benchmark datasets prove that it is fairly effective to other image patterns concerned.

  9. Series of Aerial Images over Bear River Migratory Bird Refuge, Acquired on November 7th and 9th, 1965.

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This data set includes 22 georeferenced images, acquired on November 7th and 9th, 1965, over portions of Bear River Migratory Bird Refuge, in Box Elder County,...

  10. Optimal imaging strategy for community-acquired Staphylococcus aureus musculoskeletal infections in children

    International Nuclear Information System (INIS)

    Invasive musculoskeletal infections from community-acquired methicillin-resistant and methicillin-susceptible Staphylococcus aureus (CA-SA) are increasingly encountered in children. Imaging is frequently requested in these children for diagnosis and planning of therapeutic interventions. To appraise the diagnostic efficacy of imaging practices performed for CA-SA osteomyelitis and its complications. A retrospective review was conducted of the clinical charts and imaging studies of CA-SA osteomyelitis cases since 2001 at a large children's hospital. Of 199 children diagnosed with CA-SA osteomyelitis, 160 underwent MRI examination and 35 underwent bone scintigraphy. The sensitivity of MRI and bone scintigraphy for CA-SA osteomyelitis was 98% and 53%, respectively. In all discordant cases, MRI was correct compared to bone scintigraphy. Extraosseous complications of CA-SA osteomyelitis detected only by MRI included subperiosteal abscesses (n = 77), pyomyositis (n = 43), septic arthritis (n = 31), and deep venous thrombosis (n = 12). MRI is the preferred imaging modality for the investigation of pediatric CA-SA musculoskeletal infection because it offers superior sensitivity for osteomyelitis compared to bone scintigraphy and detects extraosseous complications that occur in a substantial proportion of patients. (orig.)

  11. Optimal imaging strategy for community-acquired Staphylococcus aureus musculoskeletal infections in children

    Energy Technology Data Exchange (ETDEWEB)

    Browne, Lorna P.; Cassady, Christopher I.; Krishnamurthy, Rajesh; Guillerman, R.P. [Texas Children' s Hospital, Edward B. Singleton Department of Diagnostic Imaging, Houston, TX (United States); Mason, Edward O.; Kaplan, Sheldon L. [Texas Children' s Hospital, Department of Pediatrics, Baylor College of Medicine, Infectious Disease Service, Houston, TX (United States)

    2008-08-15

    Invasive musculoskeletal infections from community-acquired methicillin-resistant and methicillin-susceptible Staphylococcus aureus (CA-SA) are increasingly encountered in children. Imaging is frequently requested in these children for diagnosis and planning of therapeutic interventions. To appraise the diagnostic efficacy of imaging practices performed for CA-SA osteomyelitis and its complications. A retrospective review was conducted of the clinical charts and imaging studies of CA-SA osteomyelitis cases since 2001 at a large children's hospital. Of 199 children diagnosed with CA-SA osteomyelitis, 160 underwent MRI examination and 35 underwent bone scintigraphy. The sensitivity of MRI and bone scintigraphy for CA-SA osteomyelitis was 98% and 53%, respectively. In all discordant cases, MRI was correct compared to bone scintigraphy. Extraosseous complications of CA-SA osteomyelitis detected only by MRI included subperiosteal abscesses (n = 77), pyomyositis (n = 43), septic arthritis (n = 31), and deep venous thrombosis (n = 12). MRI is the preferred imaging modality for the investigation of pediatric CA-SA musculoskeletal infection because it offers superior sensitivity for osteomyelitis compared to bone scintigraphy and detects extraosseous complications that occur in a substantial proportion of patients. (orig.)

  12. Color calibration of swine gastrointestinal tract images acquired by radial imaging capsule endoscope

    Science.gov (United States)

    Ou-Yang, Mang; Jeng, Wei-De; Lai, Chien-Cheng; Wu, Hsien-Ming; Lin, Jyh-Hung

    2016-01-01

    The type of illumination systems and color filters used typically generate varying levels of color difference in capsule endoscopes, which influence medical diagnoses. In order to calibrate the color difference caused by the optical system, this study applied a radial imaging capsule endoscope (RICE) to photograph standard color charts, which were then employed to calculate the color gamut of RICE. Color gamut was also measured using a spectrometer in order to get a high-precision color information, and the results obtained using both methods were compared. Subsequently, color-correction methods, namely polynomial transform and conformal mapping, were used to improve the color difference. Before color calibration, the color difference value caused by the influences of optical systems in RICE was 21.45±1.09. Through the proposed polynomial transformation, the color difference could be reduced effectively to 1.53±0.07. Compared to another proposed conformal mapping, the color difference value was substantially reduced to 1.32±0.11, and the color difference is imperceptible for human eye because it is <1.5. Then, real-time color correction was achieved using this algorithm combined with a field-programmable gate array, and the results of the color correction can be viewed from real-time images.

  13. MaterialCloning: Acquiring Elasticity Parameters from Images for Medical Applications.

    Science.gov (United States)

    Yang, Shan; Lin, Ming C

    2016-09-01

    We present a practical approach for automatically estimating the material properties of soft bodies from two sets of images, taken before and after deformation. We reconstruct 3D geometry from the given sets of multiple-view images; we use a coupled simulation-optimization-identification framework to deform one soft body at its original, non-deformed state to match the deformed geometry of the same object in its deformed state. For shape correspondence, we use a distance-based error metric to compare the estimated deformation fields against the actual deformation field from the reconstructed geometry. The optimal set of material parameters is thereby determined by minimizing the error metric function. This method can simultaneously recover the elasticity parameters of multiple types of soft bodies using Finite Element Method-based simulation (of either linear or nonlinear materials undergoing large deformation) and particle-swarm optimization methods. We demonstrate this approach on real-time interaction with virtual organs in patient-specific surgical simulation, using parameters acquired from low-resolution medical images. We also highlight the results on physics-based animation of virtual objects using sketches from an artist's conception. PMID:26661471

  14. 99mTc-ECD brain SPECT imaging in patients with acquired immunodeficiency syndromes

    International Nuclear Information System (INIS)

    In order to investigate the changes of regional cerebral blood flow (rCBF) in patients with acquired immunodeficiency syndromes (AIDS), 99mTc-ECD brain SPECT imaging was performed in 5 patients with AIDS and 16 sex and age matched normal controls, and the rCBF percentages compared to the cerebellum were calculated using a semi-quantitative processing software. Hypo-perfusions in the right and left frontal, temporal, parietal lobe, basal ganglia and left thalamus were seen in 1 patient with dementia. Hypo-perfusions in the right and left frontal and temporal lobe were seen in 4 asymptomatic patients. The rCBF in the right and left frontal, temporal, parietal lobe, basal ganglia and thalamus, front and pons were decreased significantly in patients with AIDS than those of the control subjects (p < 0.005). It is concluded that there exists reduced cortico-subcortical rCBF in AIDS patients

  15. Non-negative factor analysis supporting the interpretation of elemental distribution images acquired by XRF

    International Nuclear Information System (INIS)

    Stacks of elemental distribution images acquired by XRF can be difficult to interpret, if they contain high degrees of redundancy and components differing in their quantitative but not qualitative elemental composition. Factor analysis, mainly in the form of Principal Component Analysis (PCA), has been used to reduce the level of redundancy and highlight correlations. PCA, however, does not yield physically meaningful representations as they often contain negative values. This limitation can be overcome, by employing factor analysis that is restricted to non-negativity. In this paper we present the first application of the Python Matrix Factorization Module (pymf) on XRF data. This is done in a case study on the painting Saul and David from the studio of Rembrandt van Rijn. We show how the discrimination between two different Co containing compounds with minimum user intervention and a priori knowledge is supported by Non-Negative Matrix Factorization (NMF).

  16. 99mTc-ECD brain SPECT imaging in patients with acquired immunodeficiency syndromes

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    In order to investigate the changes of regional cerebral blood flow(rCBF) in patients with acquired immunodeficiency syndromes (AIDS), 99mTc-ECDbrain SPECT imaging was performed in 5 patients with AIDS and 16 sex and agematched normal controls, and the rCBF percentages compared to the cerebellum werecalculated using a semi-quantitative processing software. Hypoperfusions in the rightand left frontal, temporal, porietal lobe, basal ganglia and left thalamus were seen in1 patient with dementia. Hypoperfusions in the right and left frontal and temporallobe were seen in 4 asymptomatic patients. The rCBF in the right and left frontal.temporal, porietal lobe, basal ganglia and thalamus, front and pons were decreasedsignificantly in patients with AIDS than those of the control subjects (p <0.005). Itis concluded that there exists reduced cortico-subcortical rCBF in AIDS patients.``

  17. Improvements to the three-color optical CCD-based pyrometer system

    International Nuclear Information System (INIS)

    We put forward an improved three-color measurement scheme with a color CCD sensor using the combination of effective wavelengths and blackbody calibrations. The process of effective wavelengths realizes the separation of the emissivity function from the measurement integral equation. This improved method not only effectively avoids errors arising from the traditional process adopting the basic wavelengths, but also simplifies the complex integral calculations. For a blackbody or graybody, the measurement performance of the pyrometer was experimentally investigated from the point of the temperature sensitivity. The results show that narrowing the spectrum bandwidth with different bandpass spectral filters may improve the temperature sensitivities. The spectrum adjustment not only makes the linear emissivity more suitable in the narrower waveband, but also reduces the numerical uncertainty of the effective wavelengths. For nongray objects, the effects of the numerical uncertainty of the effective wavelengths to measurements were quantificationally evaluated at different measurement conditions (different temperatures, emissivities, and spectrums). The results indicate that the reference values of 584, 555, and 511nm or 607, 560, and 506nm of the effective wavelengths are reasonable for the present system with the modified spectral response using Filter 1 or Filter 2. The maximum calculation errors arising from the reference effective wavelengths are less than 1.6%. In this paper, the technical realization steps of the improved method are also described. The measurement experiments of a metal sample in hot environments were carried out to further verify the applicability of this improved CCD-based pyrometer. The results agreed well with the spectrometer-based results.

  18. Traffic sign detection in MLS acquired point clouds for geometric and image-based semantic inventory

    Science.gov (United States)

    Soilán, Mario; Riveiro, Belén; Martínez-Sánchez, Joaquín; Arias, Pedro

    2016-04-01

    Nowadays, mobile laser scanning has become a valid technology for infrastructure inspection. This technology permits collecting accurate 3D point clouds of urban and road environments and the geometric and semantic analysis of data became an active research topic in the last years. This paper focuses on the detection of vertical traffic signs in 3D point clouds acquired by a LYNX Mobile Mapper system, comprised of laser scanning and RGB cameras. Each traffic sign is automatically detected in the LiDAR point cloud, and its main geometric parameters can be automatically extracted, therefore aiding the inventory process. Furthermore, the 3D position of traffic signs are reprojected on the 2D images, which are spatially and temporally synced with the point cloud. Image analysis allows for recognizing the traffic sign semantics using machine learning approaches. The presented method was tested in road and urban scenarios in Galicia (Spain). The recall results for traffic sign detection are close to 98%, and existing false positives can be easily filtered after point cloud projection. Finally, the lack of a large, publicly available Spanish traffic sign database is pointed out.

  19. Reliability of Calf Bioelectrical Impedance Spectroscopy and Magnetic-Resonance-Imaging-Acquired Skeletal Muscle Hydration Measures in Healthy People

    OpenAIRE

    Anuradha Sawant; House, Andrew A; Chesworth, Bert M.; Joseph Gati; Robert Lindsay; Connelly, Denise M.; Robert Bartha; Overend, Tom J.

    2013-01-01

    Purpose. The purpose of this study was to investigate the test-retest reliability, relative variability, and agreement between calf bioelectrical impedance-spectroscopy (cBIS) acquired extracellular fluid (ECF), intracellular fluid (ICF), total water and the ratio of ECF : ICF, magnetic-resonance-imaging (MRI) acquired transverse relaxation times (T2), and apparent diffusion coefficient (ADC) of calf muscles of the same segment in healthy individuals. Methods. Muscle hydration measures were c...

  20. Correlation of diagnostic imaging and autopsy findings of eight patients with acquired immune deficiency syndrome

    International Nuclear Information System (INIS)

    Objective: To investigate the imaging findings with pathologic correlation in patients with acquired immune deficiency syndrome (AIDS). Methods: Imaging findings, autopsy and pathological data were retrospectively analyzed in eight patients with AIDS. Routine CT scanning of different body parts was performed during their hospitalization. CT scanning was performed from the skull to the pelvis immediately following their death. After routine formalin fixing, 7 cadavers were cross sectioned for autopsy in freezing state and 1 for gross autopsy. Tissues were obtained from each sections and organs for pathological examinations. Results: The autopsy data showed parasitic infections (5 cases), bacterial infections (3 cases), fungal infections (2 cases), virus infections (2 cases), lymphoma (1 case) and cerebrovascular diseases (1 case)in eight patients with AIDS. The CT scanning demonstrated symmetrical ground glass liked shadows with pulmonary hilus as the center in 5 cases of pulmonary PCP infection; pulmonary patchy shadows, scattering distribution of nodular shadows, extensive military nodular shadows with even distribution and tuberculous pleurisy; cloudy shadows for 2 cases of fungi infection with multiple foci of chronic inflammation; pulmonary net-like parenchymal changes for 2 cases of pulmonary CMV infection; thickened intestinal wall and narrowed intestinal lumen for 1 case of intestinal tumor; low density shadows of brain tissue for 1 case of CMV encephalitis and MRI findings of high T1 and high T2 signals as well as MRA findings of broken vascular channels in liquefied areas of brain tissues; patchy low density areas inside a cyst of brain for one case of brain toxoplasmosis infection; multiple small patchy low density areas in cerebral basal ganglia for one case of brain cryptococcus infection. Conclusions: In AIDS patients, infection and tumor may occur in various organs resulting in complex symptoms, which makes it more complicated and difficult to make

  1. Estimating Plant Traits of Grasslands from UAV-Acquired Hyperspectral Images: A Comparison of Statistical Approaches

    Directory of Open Access Journals (Sweden)

    Alessandra Capolupo

    2015-12-01

    Full Text Available Grassland ecosystems cover around 40% of the entire Earth’s surface. Therefore, it is necessary to guarantee good grassland management at field scale in order to improve its conservation and to achieve optimal growth. This study identified the most appropriate statistical strategy, between partial least squares regression (PLSR and narrow vegetation indices, for estimating the structural and biochemical grassland traits from UAV-acquired hyperspectral images. Moreover, the influence of fertilizers on plant traits for grasslands was analyzed. Hyperspectral data were collected from an experimental field at the farm Haus Riswick, near Kleve in Germany, for two different flight campaigns in May and October. The collected image blocks were geometrically and radiometrically corrected for surface reflectance. Spectral signatures extracted for the plots were adopted to derive grassland traits by computing PLSR and the following narrow vegetation indices: the MERIS Terrestrial Chlorophyll Index (MTCI, the ratio of the Modified Chlorophyll Absorption in Reflectance and Optimized Soil-Adjusted Vegetation Index (MCARI/OSAVI modified by Wu, the Red-edge Chlorophyll Index (CIred-edge, and the Normalized Difference Red Edge (NDRE. PLSR showed promising results for estimating grassland structural traits and gave less satisfying outcomes for the selected chemical traits (crude ash, crude fiber, crude protein, Na, K, metabolic energy. Established relations are not influenced by the type and the amount of fertilization, while they are affected by the grassland health status. PLSR is found to be the best strategy, among the approaches analyzed in this paper, for exploring structural and biochemical features of grasslands. Using UAV-based hyperspectral sensing allows for the highly detailed assessment of grassland experimental plots.

  2. Road Signs Detection and Recognition Utilizing Images and 3d Point Cloud Acquired by Mobile Mapping System

    Science.gov (United States)

    Li, Y. H.; Shinohara, T.; Satoh, T.; Tachibana, K.

    2016-06-01

    High-definition and highly accurate road maps are necessary for the realization of automated driving, and road signs are among the most important element in the road map. Therefore, a technique is necessary which can acquire information about all kinds of road signs automatically and efficiently. Due to the continuous technical advancement of Mobile Mapping System (MMS), it has become possible to acquire large number of images and 3d point cloud efficiently with highly precise position information. In this paper, we present an automatic road sign detection and recognition approach utilizing both images and 3D point cloud acquired by MMS. The proposed approach consists of three stages: 1) detection of road signs from images based on their color and shape features using object based image analysis method, 2) filtering out of over detected candidates utilizing size and position information estimated from 3D point cloud, region of candidates and camera information, and 3) road sign recognition using template matching method after shape normalization. The effectiveness of proposed approach was evaluated by testing dataset, acquired from more than 180 km of different types of roads in Japan. The results show a very high success in detection and recognition of road signs, even under the challenging conditions such as discoloration, deformation and in spite of partial occlusions.

  3. Stigma models: Testing hypotheses of how images of Nevada are acquired and values are attached to them

    Energy Technology Data Exchange (ETDEWEB)

    Jenkins-Smith, H.C. [New Mexico Univ., Albuquerque, NM (United States)

    1994-12-01

    This report analyzes data from surveys on the effects that images associated with nuclear power and waste (i.e., nuclear images) have on people`s preference to vacation in Nevada. The analysis was stimulated by a model of imagery and stigma which assumes that information about a potentially hazardous facility generates signals that elicit negative images about the place in which it is located. Individuals give these images negative values (valences) that lessen their desire to vacation, relocate, or retire in that place. The model has been used to argue that the proposed Yucca Mountain high-level nuclear waste repository could elicit images of nuclear waste that would stigmatize Nevada and thus impose substantial economic losses there. This report proposes a revised model that assumes that the acquisition and valuation of images depend on individuals` ideological and cultural predispositions and that the ways in which new images will affect their preferences and behavior partly depend on these predispositions. The report tests these hypotheses: (1) individuals with distinct cultural and ideological predispositions have different propensities for acquiring nuclear images, (2) these people attach different valences to these images, (3) the variations in these valences are important, and (4) the valences of the different categories of images within an individual`s image sets for a place correlate very well. The analysis largely confirms these hypotheses, indicating that the stigma model should be revised to (1) consider the relevant ideological and cultural predispositions of the people who will potentially acquire and attach value to the image, (2) specify the kinds of images that previously attracted people to the host state, and (3) consider interactions between the old and potential new images of the place. 37 refs., 18 figs., 17 tabs.

  4. Stigma models: Testing hypotheses of how images of Nevada are acquired and values are attached to them

    International Nuclear Information System (INIS)

    This report analyzes data from surveys on the effects that images associated with nuclear power and waste (i.e., nuclear images) have on people's preference to vacation in Nevada. The analysis was stimulated by a model of imagery and stigma which assumes that information about a potentially hazardous facility generates signals that elicit negative images about the place in which it is located. Individuals give these images negative values (valences) that lessen their desire to vacation, relocate, or retire in that place. The model has been used to argue that the proposed Yucca Mountain high-level nuclear waste repository could elicit images of nuclear waste that would stigmatize Nevada and thus impose substantial economic losses there. This report proposes a revised model that assumes that the acquisition and valuation of images depend on individuals' ideological and cultural predispositions and that the ways in which new images will affect their preferences and behavior partly depend on these predispositions. The report tests these hypotheses: (1) individuals with distinct cultural and ideological predispositions have different propensities for acquiring nuclear images, (2) these people attach different valences to these images, (3) the variations in these valences are important, and (4) the valences of the different categories of images within an individual's image sets for a place correlate very well. The analysis largely confirms these hypotheses, indicating that the stigma model should be revised to (1) consider the relevant ideological and cultural predispositions of the people who will potentially acquire and attach value to the image, (2) specify the kinds of images that previously attracted people to the host state, and (3) consider interactions between the old and potential new images of the place. 37 refs., 18 figs., 17 tabs

  5. Association between muscle hydration measures acquired using bioelectrical impedance spectroscopy and magnetic resonance imaging in healthy and hemodialysis population

    OpenAIRE

    Sawant, Anuradha; House, Andrew A; Chesworth, Bert M.; Connelly, Denise M.; Lindsay, Robert; Gati, Joe; Bartha, Robert; Overend, Tom J.

    2015-01-01

    Abstract Establishing the effect of fluctuating extracellular fluid (ECF) volume on muscle strength in people with end‐stage renal disease (ESRD) on hemodialysis (HD) is essential, as inadequate hydration of the skeletal muscles impacts its strength and endurance. Bioelectrical impedance spectroscopy (BIS) has been a widely used method for estimating ECF volume of a limb or calf segment. Magnetic resonance imaging (MRI)‐acquired transverse relaxation times (T 2) has also been used for estimat...

  6. Radiometric Normalization of Large Airborne Image Data Sets Acquired by Different Sensor Types

    Science.gov (United States)

    Gehrke, S.; Beshah, B. T.

    2016-06-01

    Generating seamless mosaics of aerial images is a particularly challenging task when the mosaic comprises a large number of im-ages, collected over longer periods of time and with different sensors under varying imaging conditions. Such large mosaics typically consist of very heterogeneous image data, both spatially (different terrain types and atmosphere) and temporally (unstable atmo-spheric properties and even changes in land coverage). We present a new radiometric normalization or, respectively, radiometric aerial triangulation approach that takes advantage of our knowledge about each sensor's properties. The current implementation supports medium and large format airborne imaging sensors of the Leica Geosystems family, namely the ADS line-scanner as well as DMC and RCD frame sensors. A hierarchical modelling - with parameters for the overall mosaic, the sensor type, different flight sessions, strips and individual images - allows for adaptation to each sensor's geometric and radiometric properties. Additional parameters at different hierarchy levels can compensate radiome-tric differences of various origins to compensate for shortcomings of the preceding radiometric sensor calibration as well as BRDF and atmospheric corrections. The final, relative normalization is based on radiometric tie points in overlapping images, absolute radiometric control points and image statistics. It is computed in a global least squares adjustment for the entire mosaic by altering each image's histogram using a location-dependent mathematical model. This model involves contrast and brightness corrections at radiometric fix points with bilinear interpolation for corrections in-between. The distribution of the radiometry fixes is adaptive to each image and generally increases with image size, hence enabling optimal local adaptation even for very long image strips as typi-cally captured by a line-scanner sensor. The normalization approach is implemented in HxMap software. It has been

  7. Computed tomography and magnetic resonance imaging of acquired abnormalities of the inner ear and cerebello-pontine angle

    International Nuclear Information System (INIS)

    CT and MRI of acquired abnormalities of the inner ear and cerebello-pontine angle present themselves with very typical findings. The imaging should be adapted to the pathology looked for and either CT or MRI should be used alone or in combination.CT, especially high resolution CT (HRCT), provides an excellent bone contrast, while MRI has a much superior soft tissue contrast. Acute inflammatory changes of the inner ear are solely depicted by contrast-enhanced MRI. HRCT excellently depicts osseous changes of the inner ear and cerebellopontine angle such as chronic ossifying labyrinthitis occurring after acute labyrinthitis, otosclerotic or traumatic changes. Tumorous changes not yielding to bony changes are best delineated by MRI. Posttraumatic hemorrhage and chronic fibrotic changes within the labyrinth are depicted by MRI, only. In conclusion HRCT and MRI are excellent methods to delineate acquired abnormalities of the inner ear and cerebello-pontine angle. HRCT best depicts osseous changes while MRI best depicts soft tissue changes. HRCT and MRI are not concurrent methods but should better be used as complementary methods for imaging acquired abnormalities of inner ear and cerebellopontine angle. (orig.)

  8. Acquiring Double Images: White Preservice Teachers Locating Themselves in a Raced World

    Science.gov (United States)

    Seidl, Barbara L.; Hancock, Stephen D.

    2011-01-01

    In this article, Barbara Seidl and Stephen Hancock introduce the concept of a double image, which they argue is central to the development of a mature, antiracist identity for White people. Similar in some ways to Dubois's (1903) concept of "double consciousness," a double image is a sensibility or consciousness that gives White people a deeper…

  9. Development of CCD-based optical computed tomography and comparison with single-beam optical CT scanner

    International Nuclear Information System (INIS)

    This study reports on the development of CCD-based optical computed tomography (CT) CT-s2. A commercially available 10× fast optical computed tomography scanner (OCTOPUSTM-10X, MGS Research, Inc., Madison, CT, USA) was used for comparison. NIPAM polymer gel dosimeter was used to validate the performance of CT-s2. The gamma pass rate can reach 96.00% when using a 3% dose difference and 3 mm dose-to-agreement criteria. The results of CT-s2 are as good as those of the single-beam optical-CT scanner, but the scanning time of CT-s2 is only one-tenth of that of the single-beam optical-CT scanner

  10. Reliability of Calf Bioelectrical Impedance Spectroscopy and Magnetic-Resonance-Imaging-Acquired Skeletal Muscle Hydration Measures in Healthy People

    Directory of Open Access Journals (Sweden)

    Anuradha Sawant

    2013-01-01

    Full Text Available Purpose. The purpose of this study was to investigate the test-retest reliability, relative variability, and agreement between calf bioelectrical impedance-spectroscopy (cBIS acquired extracellular fluid (ECF, intracellular fluid (ICF, total water and the ratio of ECF : ICF, magnetic-resonance-imaging (MRI acquired transverse relaxation times (T2, and apparent diffusion coefficient (ADC of calf muscles of the same segment in healthy individuals. Methods. Muscle hydration measures were collected in 32 healthy individuals on two occasions and analyzed by a single rater. On both occasions, MRI measures were collected from tibialis anterior (TA, medial (MG, and lateral gastrocnemius (LG and soleus muscles following the cBIS data acquired using XiTRON Hydra 4200 BIS device. The intraclass correlation coefficients (ICC2,1, coefficient of variation (CV, and agreement between MRI and cBIS data were also calculated. Results. ICC2,1 values for cBIS, T2, and ADC ranged from 0.56 to 0.92, 0.96 to 0.99, and 0.05 to 0.56, respectively. Relative variability between measures (CV ranged from 14.6 to 25.6% for the cBIS data and 4.2 to 10.0% for the MRI-acquired data. The ratio of ECF : ICF could significantly predict T2 of TA and soleus muscles. Conclusion. MRI-acquired measures of T2 had the highest test-retest reliability of muscle hydration with the least error and variation on repeated testing. Hence, T2 of a muscle is the most reliable and stable outcome measure for evaluating individual muscle hydration.

  11. CCD-based high resolution digital radiography system for non destructive evaluation

    International Nuclear Information System (INIS)

    Film radiography has long served the aerospace industry as a principal method for hardware flaw detection. Although excellent in performance, this method is extremely time consuming, labor intensive, costly, and is unsuitable for real time inspections. Modem digital radiographic systems overcome some of these difficulties but are also limited in terms of speed of operation due to persistence of the sensor and a problematic tradeoff between the X-ray detection efficiency and spatial resolution. We are developing an innovative X-ray imaging detector consisting of a novel microstructured CsI scintillator coupled to a fiberoptic taper-based CCD. Thin-film deposition techniques, previously developed to produce thin, structured CsI screens have been extended to fabricate CsI screens, up to 450 mg/cm2 (1,000 μm) in thickness. These sensors are suitable to provide high detection efficiency with high image quality for NDE applications. A prototype high energy imaging system was constructed by integrating these screens into a fiber-optic-based CCD camera. The performance was compared to that of the same system using a standard polycrystalline phosphor for NDE imaging applications. The experimental evaluations were carried out at Scientific Measurement Systems, Inc., Austin, TX

  12. SU-E-J-176: Results of Images Acquired with Backscattered MV Radiation Using a Pinhole Collimator

    Energy Technology Data Exchange (ETDEWEB)

    Bernard, D; Turian, J; Wu, Z; Darwish, N; Chu, J; Bernard, D [Rush University Medical Center, Chicago, IL (United States)

    2014-06-01

    Purpose: To ascertain the feasibility of acquiring real time images of small lung tumors from scattered photons while undergoing radiation treatment.There are several methodologies currently used to track tumor location such as MV-cine acquisition and kV fluoroscopy. However, MVcine offers no information parallel to the beam axis while kV fluoroscopy offers little potential for soft tissue discernability while also increasing the patient dose. This study investigates the feasibility of observing an actual simulated tumor while exploring techniques that may improve image quality. Methods: A prototype imager consisting of a gamma camera pinhole collimator and a computed radiography (CR) plate were used in conjunction with a Varian TrueBeam linac. One study consisted of a 2.5 cm diameter solid water cylinder representing a solid tumor imbedded within a lung equivalent material slab. The cylinder with the lung slab was sandwiched between 1 cm lung equivalent slabs and these were sandwiched between 2 slabs of solid water. The top water slab was 1 cm thick. The other imaging study consisted of three different density plugs, 0.46, 1.09, and 1.82 g/cm3 placed on the accelerator couch. The gantry was orientated 70° relative to the CR plate. The slabs and plugs were irradiated with 2000 MU and 500 MU respectively using the 6FFF mode. Results: The solid water plug was visually discernible in the slab phantom. The ratio of the signal coming from the higher density plugs (placed on the treatment couch) to that between the plugs increased from 1.02 to about 3.0 after subtracting the background image acquired with no plugs present. Conclusion: Preliminary results indicate that a lung tumor could be visualized with scattered radiation during treatment. Improvements in discerning an object can be enhanced by filtering out the head leakage and background scattered radiation not emanating from the imaged object.

  13. Modelling temporal stability of EPI time series using magnitude images acquired with multi-channel receiver coils.

    Directory of Open Access Journals (Sweden)

    Chloe Hutton

    Full Text Available In 2001, Krueger and Glover introduced a model describing the temporal SNR (tSNR of an EPI time series as a function of image SNR (SNR(0. This model has been used to study physiological noise in fMRI, to optimize fMRI acquisition parameters, and to estimate maximum attainable tSNR for a given set of MR image acquisition and processing parameters. In its current form, this noise model requires the accurate estimation of image SNR. For multi-channel receiver coils, this is not straightforward because it requires export and reconstruction of large amounts of k-space raw data and detailed, custom-made image reconstruction methods. Here we present a simple extension to the model that allows characterization of the temporal noise properties of EPI time series acquired with multi-channel receiver coils, and reconstructed with standard root-sum-of-squares combination, without the need for raw data or custom-made image reconstruction. The proposed extended model includes an additional parameter κ which reflects the impact of noise correlations between receiver channels on the data and scales an apparent image SNR (SNR'(0 measured directly from root-sum-of-squares reconstructed magnitude images so that κ = SNR'(0/SNR(0 (under the condition of SNR(0>50 and number of channels ≤32. Using Monte Carlo simulations we show that the extended model parameters can be estimated with high accuracy. The estimation of the parameter κ was validated using an independent measure of the actual SNR(0 for non-accelerated phantom data acquired at 3T with a 32-channel receiver coil. We also demonstrate that compared to the original model the extended model results in an improved fit to human task-free non-accelerated fMRI data acquired at 7T with a 24-channel receiver coil. In particular, the extended model improves the prediction of low to medium tSNR values and so can play an important role in the optimization of high-resolution fMRI experiments at lower SNR levels.

  14. Series of aerial images over Quivira National Wildlife Refuge, acquired on June , 1985

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This data set is of nine georeferenced aerial images taken over Quivira National Wildlife Refuge on June 19th and 27th, 1985. This data set is a clipped,...

  15. Fully automated rodent brain MR image processing pipeline on a Midas server: from acquired images to region-based statistics.

    Science.gov (United States)

    Budin, Francois; Hoogstoel, Marion; Reynolds, Patrick; Grauer, Michael; O'Leary-Moore, Shonagh K; Oguz, Ipek

    2013-01-01

    Magnetic resonance imaging (MRI) of rodent brains enables study of the development and the integrity of the brain under certain conditions (alcohol, drugs etc.). However, these images are difficult to analyze for biomedical researchers with limited image processing experience. In this paper we present an image processing pipeline running on a Midas server, a web-based data storage system. It is composed of the following steps: rigid registration, skull-stripping, average computation, average parcellation, parcellation propagation to individual subjects, and computation of region-based statistics on each image. The pipeline is easy to configure and requires very little image processing knowledge. We present results obtained by processing a data set using this pipeline and demonstrate how this pipeline can be used to find differences between populations. PMID:23964234

  16. Fully automated rodent brain MR image processing pipeline on a Midas server: from acquired images to region-based statistics

    Directory of Open Access Journals (Sweden)

    Francois Budin

    2013-08-01

    Full Text Available Magnetic Resonance Imaging (MRI of rodent brains enables study of the development and the integrity of the brain under certain conditions (alcohol, drugs etc.. However, these images are difficult to analyze for biomedical researchers with limited image processing experience. In this paper we present an image processing pipeline running on a Midas server, a web-based data storage system. It is composed of the following steps: rigid registration, skull-stripping, average computation, average segmentation, segmentation propagation to individual subjects and computation of region-based statistics on each image. The pipeline is easy to configure and requires very little image processing knowledge. We present results obtained by processing a data set using this pipeline and demonstrate how this pipeline can be used to find differences between populations.

  17. ROPtool analysis of images acquired using a noncontact handheld fundus camera (Pictor)--a pilot study.

    Science.gov (United States)

    Vickers, Laura A; Freedman, Sharon F; Wallace, David K; Prakalapakorn, S Grace

    2015-12-01

    The presence of plus disease is the primary indication for treatment of retinopathy of prematurity (ROP), but its diagnosis is subjective and prone to error. ROPtool is a semiautomated computer program that quantifies vascular tortuosity and dilation. Pictor is an FDA-approved, noncontact, handheld digital fundus camera. This pilot study evaluated ROPtool's ability to analyze high-quality Pictor images of premature infants and its accuracy in diagnosing plus disease compared to clinical examination. In our small sample of images, ROPtool could trace and identify the presence of plus disease with high accuracy. PMID:26691046

  18. Three-dimensional imaging applications in Earth Sciences using video data acquired from an unmanned aerial vehicle

    Science.gov (United States)

    McLeod, Tara

    For three dimensional (3D) aerial images, unmanned aerial vehicles (UAVs) are cheaper to operate and easier to fly than the typical manned craft mounted with a laser scanner. This project explores the feasibility of using 2D video images acquired with a UAV and transforming them into 3D point clouds. The Aeryon Scout -- a quad-copter micro UAV -- flew two missions: the first at York University Keele campus and the second at the Canadian Wollastonite Mine Property. Neptec's ViDAR software was used to extract 3D information from the 2D video using structure from motion. The resulting point clouds were sparsely populated, yet captured vegetation well. They were used successfully to measure fracture orientation in rock walls. Any improvement in the video resolution would cascade through the processing and improve the overall results.

  19. Series of aerial images over Quivira National Wildlife Refuge, acquired October, 1938

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This data set is composite of original black and white series images obtained from Earth Explorer USGS on October 1st, 5th and 12th, 1938. The original photos were...

  20. Acquiring Multiview C-Arm Images to Assist Cardiac Ablation Procedures

    Directory of Open Access Journals (Sweden)

    Pascal Fallavollita

    2010-01-01

    Full Text Available CARTO XP is an electroanatomical cardiac mapping system that provides 3D color-coded maps of the electrical activity of the heart; however it is expensive and it can only use a single costly magnetic catheter for each patient intervention. Our approach consists of integrating fluoroscopic and electrical data from the RF catheters into the same image so as to better guide RF ablation, shorten the duration of this procedure, increase its efficacy, and decrease hospital cost when compared to CARTO XP. We propose a method that relies on multi-view C-arm fluoroscopy image acquisition for (1 the 3D reconstruction of the anatomical structure of interest, (2 the robust temporal tracking of the tip-electrode of a mapping catheter between the diastolic and systolic phases and (3 the 2D/3D registration of color coded isochronal maps directly on the 2D fluoroscopy image that would help the clinician guide the ablation procedure much more effectively. The method has been tested on canine experimental data.

  1. Fast Orientation of Video Images of Buildings Acquired from a UAV without Stabilization

    Directory of Open Access Journals (Sweden)

    Michal Kedzierski

    2016-06-01

    Full Text Available The aim of this research was to assess the possibility of conducting an absolute orientation procedure for video imagery, in which the external orientation for the first image was typical for aerial photogrammetry whereas the external orientation of the second was typical for terrestrial photogrammetry. Starting from the collinearity equations, assuming that the camera tilt angle is equal to 90°, a simplified mathematical model is proposed. The proposed method can be used to determine the X, Y, Z coordinates of points based on a set of collinearity equations of a pair of images. The use of simplified collinearity equations can considerably shorten the processing tine of image data from Unmanned Aerial Vehicles (UAVs, especially in low cost systems. The conducted experiments have shown that it is possible to carry out a complete photogrammetric project of an architectural structure using a camera tilted 85°–90° ( φ or ω and simplified collinearity equations. It is also concluded that there is a correlation between the speed of the UAV and the discrepancy between the established and actual camera tilt angles.

  2. Fast Orientation of Video Images of Buildings Acquired from a UAV without Stabilization.

    Science.gov (United States)

    Kedzierski, Michal; Delis, Paulina

    2016-01-01

    The aim of this research was to assess the possibility of conducting an absolute orientation procedure for video imagery, in which the external orientation for the first image was typical for aerial photogrammetry whereas the external orientation of the second was typical for terrestrial photogrammetry. Starting from the collinearity equations, assuming that the camera tilt angle is equal to 90°, a simplified mathematical model is proposed. The proposed method can be used to determine the X, Y, Z coordinates of points based on a set of collinearity equations of a pair of images. The use of simplified collinearity equations can considerably shorten the processing tine of image data from Unmanned Aerial Vehicles (UAVs), especially in low cost systems. The conducted experiments have shown that it is possible to carry out a complete photogrammetric project of an architectural structure using a camera tilted 85°-90° ( φ or ω) and simplified collinearity equations. It is also concluded that there is a correlation between the speed of the UAV and the discrepancy between the established and actual camera tilt angles. PMID:27347954

  3. Fast Orientation of Video Images of Buildings Acquired from a UAV without Stabilization

    Science.gov (United States)

    Kedzierski, Michal; Delis, Paulina

    2016-01-01

    The aim of this research was to assess the possibility of conducting an absolute orientation procedure for video imagery, in which the external orientation for the first image was typical for aerial photogrammetry whereas the external orientation of the second was typical for terrestrial photogrammetry. Starting from the collinearity equations, assuming that the camera tilt angle is equal to 90°, a simplified mathematical model is proposed. The proposed method can be used to determine the X, Y, Z coordinates of points based on a set of collinearity equations of a pair of images. The use of simplified collinearity equations can considerably shorten the processing tine of image data from Unmanned Aerial Vehicles (UAVs), especially in low cost systems. The conducted experiments have shown that it is possible to carry out a complete photogrammetric project of an architectural structure using a camera tilted 85°–90° (φ or ω) and simplified collinearity equations. It is also concluded that there is a correlation between the speed of the UAV and the discrepancy between the established and actual camera tilt angles. PMID:27347954

  4. A CCD-based system for the detection of DNA in electrophoresis gels by UV absorption

    International Nuclear Information System (INIS)

    A method and apparatus for the detection and quantification of large fragments of unlabelled nucleic acids in agarose gels is presented. The technique is based on ultraviolet (UV) absorption by nucleotides. A deuterium source illuminates individual sample lanes of an electrophoresis gel via an array of optical fibres. As DNA bands pass through the illuminated region of the gel the amount of UV light transmitted is reduced because of absorption by the DNA. During electrophoresis the regions of DNA are detected on-line using a UV-sensitive charge coupled device (CCD). As the absorption coefficient is proportional to the mass of DNA the technique is inherently quantitative. The mass of DNA in a region of the gel is approximately proportional to the integrated signal in the corresponding section of the CCD image. This system currently has a detection limit of less than 1.25 ng compared with 2-10 ng for the most popular conventional technique, ethidium bromide (EtBr) staining. In addition the DNA sample remains in its native state. The removal of the carcinogenic dye from the detection procedure greatly reduces associated biological hazards. (author)

  5. Large area high-resolution CCD-based X-ray detector for macromolecular crystallography

    CERN Document Server

    Pokric, M; Jorden, A R; Cox, M P; Marshall, A; Long, P G; Moon, K; Jerram, P A; Pool, P; Nave, C; Derbyshire, G E; Helliwell, J R

    2002-01-01

    An X-ray detector system for macromolecular crystallography based on a large area charge-coupled device (CCD) sensor has been developed as part of a large research and development programme for advanced X-ray sensor technology, funded by industry and the Particle Physics and Astronomy Research Council (PPARC) in the UK. The prototype detector consists of two large area three-sides buttable charge-coupled devices (CCD 46-62 EEV), where the single CCD area is 55.3 mmx41.5 mm. Overall detector imaging area is easily extendable to 85 mmx110 mm. The detector consists of an optically coupled X-ray sensitive phosphor, skewed fibre-optic studs and CCDs. The crystallographic measurement requirements at synchrotron sources are met through a high spatial resolution (2048x1536 pixel array), high dynamic range (approx 10 sup 5), a fast readout (approx 1 s), low noise (<10e sup -) and much reduced parallax error. Additionally, the prototype detector system has been optimised by increasing its efficiency at low X-ray ene...

  6. Maximum-likelihood scintillation detection for EM-CCD based gamma cameras

    International Nuclear Information System (INIS)

    Gamma cameras based on charge-coupled devices (CCDs) coupled to continuous scintillation crystals can combine a good detection efficiency with high spatial resolutions with the aid of advanced scintillation detection algorithms. A previously developed analytical multi-scale algorithm (MSA) models the depth-dependent light distribution but does not take statistics into account. Here we present and validate a novel statistical maximum-likelihood algorithm (MLA) that combines a realistic light distribution model with an experimentally validated statistical model. The MLA was tested for an electron multiplying CCD optically coupled to CsI(Tl) scintillators of different thicknesses. For 99mTc imaging, the spatial resolution (for perpendicular and oblique incidence), energy resolution and signal-to-background counts ratio (SBR) obtained with the MLA were compared with those of the MSA. Compared to the MSA, the MLA improves the energy resolution by more than a factor of 1.6 and the SBR is enhanced by more than a factor of 1.3. For oblique incidence (approximately 450), the depth-of-interaction corrected spatial resolution is improved by a factor of at least 1.1, while for perpendicular incidence the MLA resolution does not consistently differ significantly from the MSA result for all tested scintillator thicknesses. For the thickest scintillator (3 mm, interaction probability 66% at 141 keV) a spatial resolution (perpendicular incidence) of 147 μm full width at half maximum (FWHM) was obtained with an energy resolution of 35.2% FWHM. These results of the MLA were achieved without prior calibration of scintillations as is needed for many statistical scintillation detection algorithms. We conclude that the MLA significantly improves the gamma camera performance compared to the MSA.

  7. SU-C-BRD-06: Sensitivity Study of An Automated System to Acquire and Analyze EPID Exit Dose Images

    Energy Technology Data Exchange (ETDEWEB)

    Olch, A; Zhuang, A [University of Southern California, Los Angeles, CA (United States)

    2015-06-15

    Purpose: The dosimetric consequences of errors in patient setup or beam delivery and anatomical changes are not readily known. A new product, PerFRACTION (Sun Nuclear Corporation), is designed to detect these errors by comparing the EPID exit dose image from each field of each fraction to those from baseline fraction images. This work investigates the sensitivity of PerFRACTION to detect the deviation of induced errors in a variety of realistic scenarios. Methods: Eight plans were created mimicking potential delivery or setup errors. The plans consisted of a nominal field and the field with an induced error. These were used to irradiate the EPID simulating multiple fractions with and without the error. Integrated EPID images were acquired in clinical mode and saved in ARIA. PerFRACTION automatically pulls the images into its database and performs the user defined comparison. In some cases, images were manually pushed to PerFRACTION. We varied the distance-to-agreement or dose tolerance until PerFRACTION showed failing pixels in the affected region and recorded the values. We induced errors of 1mm and greater in jaw, MLC, and couch position, 2 degree collimation rotation (patient yaw), and 0.5% to 1.5% in machine output. Both static and arc fields with the rails in or out were also acquired and compared. Results: PerFRACTION detected position errors of the jaws, MLC, and couch with an accuracy of better than 0.5 mm, and 0.2 degrees for collimator and gantry error. PerFRACTION detected a machine output error within 0.2% and detected the change in rail position. Conclusion: A new automated system for monitoring daily treatments for machine or patient variations from the first fraction using integrated EPID images was found to be sensitive enough to detect small positional, angular, and dosimetric errors within 0.5mm, 0.2 degrees, and 0.2%, respectively. Sun Nuclear Corporation has provided a software license for the product described.

  8. Testing of gadolinium oxy-sulphide phosphors for use in CCD-based X-ray detectors for macromolecular crystallography

    CERN Document Server

    Pokric, M

    2002-01-01

    The resolution and detective quantum efficiency of CCD-based detectors used for X-ray diffraction is primarily affected by the layer of phosphor that converts incident X-ray photons into visible photons. The optimum thickness of this phosphor layer is strongly dependent on the fraction of absorbed incident X-ray photons and required spatial resolution. A range of terbium doped gadolinium oxy-sulphide (Gd sub 2 O sub 2 S : Tb) phosphor samples, provided by Applied Scintillation Technologies, have been evaluated for spatial resolution, light output and uniformity. The phosphor samples varied in coating weight (10-25 mg/cm sup 2), grain size (2.5, 4, 10 mu m), and applied coating (no coating, reflectors and absorbers). In addition, a non-uniform layer was introduced to some samples in order to provide an inherent diffusion layer. The experimental results showed that the introduction of a reflector increases the point spread function (PSF) and increases light yield up to 30%, while an absorber reduces the PSF tai...

  9. Process monitoring and control with CHEMIN, a miniaturized CCD-based instrument for simultaneous XRD/XRF analysis

    Science.gov (United States)

    Vaniman, David T.; Bish, D.; Guthrie, G.; Chipera, S.; Blake, David E.; Collins, S. Andy; Elliott, S. T.; Sarrazin, P.

    1999-10-01

    There is a large variety of mining and manufacturing operations where process monitoring and control can benefit from on-site analysis of both chemical and mineralogic constituents. CHEMIN is a CCD-based instrument capable of both X-ray fluorescence (XRF; chemical) and X-ray diffraction (XRD; mineralogic) analysis. Monitoring and control with an instrument like CHEMIN can be applied to feedstocks, intermediate materials, and final products to optimize production. Examples include control of cement feedstock, of ore for smelting, and of minerals that pose inhalation hazards in the workplace. The combined XRD/XRF capability of CHEMIN can be used wherever a desired commodity is associated with unwanted constituents that may be similar in chemistry or structure but not both (e.g., Ca in both gypsum and feldspar, where only the gypsum is desired to make wallboard). In the mining industry, CHEMIN can determine mineral abundances on the spot and enable more economical mining by providing the means to assay when is being mined, quickly and frequently, at minimal cost. In manufacturing, CHEMIN could be used to spot-check the chemical composition and crystalline makeup of a product at any stage of production. Analysis by CHEMIN can be used as feedback in manufacturing processes where rates of heating, process temperature, mixture of feedstocks, and other variables must be adjusted in real time to correct structure and/or chemistry of the product (e.g., prevention of periclase and alkali sulfate coproduction in cement manufacture).

  10. 3D reconstruction of hollow parts analyzing images acquired by a fiberscope

    International Nuclear Information System (INIS)

    A modified fiberscope used to reconstruct difficult-to-reach inner structures is presented. By substituting the fiberscope’s original illumination system, we can project a profile-revealing light line inside the object of study. The light line is obtained using a sandwiched power light-emitting diode (LED) attached to an extension arm on the tip of the fiberscope. Profile images from the interior of the object are then captured by a camera attached to the fiberscope’s eyepiece. Using a series of those images at different positions, the system is capable of generating a 3D reconstruction of the object with submillimeter accuracy. Also proposed is the use of a combination of known filters to remove the honeycomb structures produced by the fiberscope and the use of ring gages to obtain the extrinsic parameters of the camera attached to the fiberscope and the metrological traceability of the system. Several standard ring diameter measurements were compared against their certified values to improve the accuracy of the system. To exemplify an application, a 3D reconstruction of the interior of a refrigerator duct was conducted. This reconstruction includes accuracy assessment by comparing the measurements of the system to a coordinate measuring machine. The system, as described, is capable of 3D reconstruction of the interior of objects with uniform and non-uniform profiles from 10 to 60 mm in transversal dimensions and a depth of 1000 mm if the material of the walls of the object is translucent and allows the detection of the power LED light from the exterior through the wall. If this is not possible, we propose the use of a magnetic scale which reduces the working depth to 170 mm. The assessed accuracy is around ±0.15 mm in 2D cross-section reconstructions and ±1.3 mm in 1D position using a magnetic scale, and ±0.5 mm using a CCD camera. (paper)

  11. Detection of blood-related signal from a series of fingerprint images acquired during an input action

    Science.gov (United States)

    Fujieda, Ichiro; Hori, Atsushi; Kurita, Masashi

    2007-09-01

    When a finger is pressed against a flat plate and deformed, blood inside the finger moves away from the deformed area. This causes the finger to change its appearance from reddish to white. As the finger leaves the plate, the blood comes back and it looks reddish again. We have proposed to use this color change to distinguish genuine fingers from artificial ones for un-attended fingerprint identification systems. This blood-related signal may reflect the stiffness of the peripheral blood vessels and therefore it may be correlated with some health conditions such as blood pressure. In experiments, we used a fingerprint sensor based on scattered light detection. Because the spectra of the light scattered by the deformed fingers showed large changes mostly in the green portion, an LED emitting at 525 nm at peak strength was used. First, we compared series of fingerprint images acquired during a normal input action and those obtained while a rubber band occluded the blood flow. The occluded finger required a larger force to exhibit a similar change for these pixel values than the finger without the rubber band. Second, we analyzed fingerprint images recorded by six volunteers. We defined some indices based on the pixel values of the fingerprint images and the pressure applied to the fingers. The correlation coefficient of one of such indices and the average blood pressure of the participants was 0.86. Although the number of the subjects is small, this initial result is encouraging.

  12. Pulmonary cryptococcosis in rheumatoid arthritis (RA) patients: Comparison of imaging characteristics among RA, acquired immunodeficiency syndrome, and immunocompetent patients

    Energy Technology Data Exchange (ETDEWEB)

    Yanagawa, Noriyo, E-mail: noriyo_yana@ybb.ne.jp [Departments of Radiology, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, 3-8-22, Honkomagome, Bunkyo-ku, Tokyo 113-8677 (Japan); Sakai, Fumikazu [Department of Diagnostic Radiology, Saitama Medical University International Medical Center, 1397-1 Yamane, Hidaka-shi, Saitama 350-1298 (Japan); Takemura, Tamiko [Department of Pathology, Japanese Red Cross Medical Center, 4-1-22 Hiroo, Shibuya-ku, Tokyo 150-8935 (Japan); Ishikawa, Satoru [Department of Respiratory Medicine, National Hospital Organization Chiba-East-Hospital, 673 Nitona-cho, Chuo-ku, Chiba-shi, Chiba 260-8712 (Japan); Takaki, Yasunobu [Departments of Radiology, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, 3-8-22, Honkomagome, Bunkyo-ku, Tokyo 113-8677 (Japan); Hishima, Tsunekazu [Department of Pathology, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, 3-8-22, Honkomagome, Bunkyo-ku, Tokyo 113-8677 (Japan); Kamata, Noriko [Departments of Radiology, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, 3-8-22, Honkomagome, Bunkyo-ku, Tokyo 113-8677 (Japan)

    2013-11-01

    Purpose: The imaging characteristics of cryptococcosis in rheumatoid arthritis (RA) patients were analyzed by comparing them with those of acquired immunodeficiency syndrome (AIDS) and immunocompetent patients, and the imaging findings were correlated with pathological findings. Methods: Two radiologists retrospectively compared the computed tomographic (CT) findings of 35 episodes of pulmonary cryptococcosis in 31 patients with 3 kinds of underlying states (10 RA, 12 AIDS, 13 immunocompetent), focusing on the nature, number, and distribution of lesions. The pathological findings of 18 patients (8 RA, 2 AIDS, 8 immunocompetent) were analyzed by two pathologists, and then correlated with imaging findings. Results: The frequencies of consolidation and ground glass attenuation (GGA) were significantly higher, and the frequency of peripheral distribution was significantly lower in the RA group than in the immunocompetent group. Peripheral distribution was less common and generalized distribution was more frequent in the RA group than in the AIDS group. The pathological findings of the AIDS and immunocompetent groups reflected their immune status: There was lack of a granuloma reaction in the AIDS group, and a complete granuloma reaction in the immunocompetent group, while the findings of the RA group varied, including a complete granuloma reaction, a loose granuloma reaction and a hyper-immune reaction. Cases with the last two pathologic findings were symptomatic and showed generalized or central distribution on CT. Conclusion: Cryptococcosis in the RA group showed characteristic radiological and pathological findings compared with the other 2 groups.

  13. Practically acquired and modified cone-beam computed tomography images for accurate dose calculation in head and neck cancer

    International Nuclear Information System (INIS)

    On-line cone-beam computed tomography (CBCT) may be used to reconstruct the dose for geometric changes of patients and tumors during radiotherapy course. This study is to establish a practical method to modify the CBCT for accurate dose calculation in head and neck cancer. Fan-beam CT (FBCT) and Elekta's CBCT were used to acquire images. The CT numbers for different materials on CBCT were mathematically modified to match them with FBCT. Three phantoms were scanned by FBCT and CBCT for image uniformity, spatial resolution, and CT numbers, and to compare the dose distribution from orthogonal beams. A Rando phantom was scanned and planned with intensity-modulated radiation therapy (IMRT). Finally, two nasopharyngeal cancer patients treated with IMRT had their CBCT image sets calculated for dose comparison. With 360 acquisition of CBCT and high-resolution reconstruction, the uniformity of CT number distribution was improved and the otherwise large variations for background and high-density materials were reduced significantly. The dose difference between FBCT and CBCT was < 2% in phantoms. In the Rando phantom and the patients, the dose-volume histograms were similar. The corresponding isodose curves covering ≥ 90% of prescribed dose on FBCT and CBCT were close to each other (within 2 mm). Most dosimetric differences were from the setup errors related to the interval changes in body shape and tumor response. The specific CBCT acquisition, reconstruction, and CT number modification can generate accurate dose calculation for the potential use in adaptive radiotherapy.

  14. Pulmonary cryptococcosis in rheumatoid arthritis (RA) patients: Comparison of imaging characteristics among RA, acquired immunodeficiency syndrome, and immunocompetent patients

    International Nuclear Information System (INIS)

    Purpose: The imaging characteristics of cryptococcosis in rheumatoid arthritis (RA) patients were analyzed by comparing them with those of acquired immunodeficiency syndrome (AIDS) and immunocompetent patients, and the imaging findings were correlated with pathological findings. Methods: Two radiologists retrospectively compared the computed tomographic (CT) findings of 35 episodes of pulmonary cryptococcosis in 31 patients with 3 kinds of underlying states (10 RA, 12 AIDS, 13 immunocompetent), focusing on the nature, number, and distribution of lesions. The pathological findings of 18 patients (8 RA, 2 AIDS, 8 immunocompetent) were analyzed by two pathologists, and then correlated with imaging findings. Results: The frequencies of consolidation and ground glass attenuation (GGA) were significantly higher, and the frequency of peripheral distribution was significantly lower in the RA group than in the immunocompetent group. Peripheral distribution was less common and generalized distribution was more frequent in the RA group than in the AIDS group. The pathological findings of the AIDS and immunocompetent groups reflected their immune status: There was lack of a granuloma reaction in the AIDS group, and a complete granuloma reaction in the immunocompetent group, while the findings of the RA group varied, including a complete granuloma reaction, a loose granuloma reaction and a hyper-immune reaction. Cases with the last two pathologic findings were symptomatic and showed generalized or central distribution on CT. Conclusion: Cryptococcosis in the RA group showed characteristic radiological and pathological findings compared with the other 2 groups

  15. Practically acquired and modified cone-beam computed tomography images for accurate dose calculation in head and neck cancer

    Energy Technology Data Exchange (ETDEWEB)

    Hu, Chih-Chung [National Taiwan Univ. Hospital and College of Medicine, Taipei (China). Division of Radiation Oncology; Yuanpei Univ., Hsinchu (China). Dept. of Radiological Technology; Huang, Wen-Tao [Yuanpei Univ., Hsinchu (China). Dept. of Radiological Technology; Tsai, Chiao-Ling; Chao, Hsiao-Ling; Huang, Guo-Ming; Wang, Chun-Wei [National Taiwan Univ. Hospital and College of Medicine, Taipei (China). Division of Radiation Oncology; Wu, Jian-Kuen [National Taiwan Univ. Hospital and College of Medicine, Taipei (China). Division of Radiation Oncology; National Taiwan Normal Univ., Taipei (China). Inst. of Electro-Optical Science and Technology; Wu, Chien-Jang [National Taiwan Normal Univ., Taipei (China). Inst. of Electro-Optical Science and Technology; Cheng, Jason Chia-Hsien [National Taiwan Univ. Hospital and College of Medicine, Taipei (China). Division of Radiation Oncology; National Taiwan Univ. Taipei (China). Graduate Inst. of Oncology; National Taiwan Univ. Taipei (China). Graduate Inst. of Clinical Medicine; National Taiwan Univ. Taipei (China). Graduate Inst. of Biomedical Electronics and Bioinformatics

    2011-10-15

    On-line cone-beam computed tomography (CBCT) may be used to reconstruct the dose for geometric changes of patients and tumors during radiotherapy course. This study is to establish a practical method to modify the CBCT for accurate dose calculation in head and neck cancer. Fan-beam CT (FBCT) and Elekta's CBCT were used to acquire images. The CT numbers for different materials on CBCT were mathematically modified to match them with FBCT. Three phantoms were scanned by FBCT and CBCT for image uniformity, spatial resolution, and CT numbers, and to compare the dose distribution from orthogonal beams. A Rando phantom was scanned and planned with intensity-modulated radiation therapy (IMRT). Finally, two nasopharyngeal cancer patients treated with IMRT had their CBCT image sets calculated for dose comparison. With 360 acquisition of CBCT and high-resolution reconstruction, the uniformity of CT number distribution was improved and the otherwise large variations for background and high-density materials were reduced significantly. The dose difference between FBCT and CBCT was < 2% in phantoms. In the Rando phantom and the patients, the dose-volume histograms were similar. The corresponding isodose curves covering {>=} 90% of prescribed dose on FBCT and CBCT were close to each other (within 2 mm). Most dosimetric differences were from the setup errors related to the interval changes in body shape and tumor response. The specific CBCT acquisition, reconstruction, and CT number modification can generate accurate dose calculation for the potential use in adaptive radiotherapy.

  16. A preliminary report of 99Tcm-ECD brain SPECT imaging in patients with acquired immunodeficiency syndrome

    International Nuclear Information System (INIS)

    Objective: To investigate the changes of regional cerebral blood flow (rCBF) in patients with acquired immunodeficiency syndrome (AIDS). Methods: 99Tcm-ECD brain SPECT imaging was performed on 5 patients with AIDS and 16 sex- and age-matched normal controls. The rCBF percentages compared to the cerebellum were calculated using a semi-quantitative processing software. Results: Hypo-perfusions in the right and left frontal, temporal, parietal lobe, basal ganglia and left thalamus were seen in 1 patient with dementia. Hypo-perfusions in the right and left frontal and temporal lobe were seen in 4 patients without dementia. The rCBF in the right and left frontal, temporal, parietal lobe, basal ganglia and thalamus, straight gyri and pons decreased significantly in patients with AIDS than those of the control subjects (P < 0.01). Conclusion: There is reduced cortico-subcortical rCBF in patients with AIDS

  17. Use of Variogram Parameters in Analysis of Hyperspectral Imaging Data Acquired from Dual-Stressed Crop Leaves

    Directory of Open Access Journals (Sweden)

    Christian Nansen

    2012-01-01

    Full Text Available A detailed introduction to variogram analysis of reflectance data is provided, and variogram parameters (nugget, sill, and range values were examined as possible indicators of abiotic (irrigation regime and biotic (spider mite infestation stressors. Reflectance data was acquired from 2 maize hybrids (Zea mays L. at multiple time points in 2 data sets (229 hyperspectral images, and data from 160 individual spectral bands in the spectrum from 405 to 907 nm were analyzed. Based on 480 analyses of variance (160 spectral bands × 3 variogram parameters, it was seen that most of the combinations of spectral bands and variogram parameters were unsuitable as stress indicators mainly because of significant difference between the 2 data sets. However, several combinations of spectral bands and variogram parameters (especially nugget values could be considered unique indicators of either abiotic or biotic stress. Furthermore, nugget values at 683 and 775 nm responded significantly to abiotic stress, and nugget values at 731 nm and range values at 715 nm responded significantly to biotic stress. Based on qualitative characterization of actual hyperspectral images, it was seen that even subtle changes in spatial patterns of reflectance values can elicit several-fold changes in variogram parameters despite non-significant changes in average and median reflectance values and in width of 95% confidence limits. Such scattered stress expression is in accordance with documented within-leaf variation in both mineral content and chlorophyll concentration and therefore supports the need for reflectance-based stress detection at a high spatial resolution (many hyperspectral reflectance profiles acquired from a single leaf and may be used to explain or characterize within-leaf foraging patterns of herbivorous arthropods.

  18. Imaging of acquired non-traumatic cochlear lesions: iconographic essay; Avaliacao por imagem das lesoes cocleares adquiridas (nao-traumaticas): ensaio iconografico

    Energy Technology Data Exchange (ETDEWEB)

    Garcia, Marcelo de Mattos; Gonzaga, Juliana Gontijo [Clinica Axial - Centro de Imagem, Belo Horizonte, MG (Brazil)]. E-mail: cidbh@cidbh.com.br; marcelogarcia@superig.com.br

    2006-04-15

    Different non-traumatic acquired cochlear lesions are shown in this article with imaging methods. They may be responsible for neuro sensorial hearing loss or vertigo. The method of choice is computed tomography when evaluating the osseous labyrinth whereas magnetic resonance imaging has superior resolution in the studies of the membranaceous labyrinth. (author)

  19. Characterization and optimization of images acquired by a compact soft X-ray microscope based on a double stream gas-puff target source

    International Nuclear Information System (INIS)

    Using a table-top size soft X-ray (SXR) microscope, based on a laser plasma source with a double stream gas-puff target and a Fresnel zone plate objective, series of images of test samples were acquired. Characterization and optimization of the acquisition parameters were studied and evaluated in terms of signal to noise ratio (SNR). Conclusions for the optimization of SXR imaging were reached. Similar SNR measurements might be performed to characterize other SXR imaging systems as well. Software enabling live calculation of the SNR during the image acquisition might be introduced in future in the compact imaging systems for optimal image acquisition or for benchmarking purposes

  20. Characterization and optimization of images acquired by a compact soft X-ray microscope based on a double stream gas-puff target source

    Science.gov (United States)

    Torrisi, A.; Wachulak, P.; Fahad Nawaz, M.; Bartnik, A.; Węgrzyński, L.; Jancarek, A.; Fiedorowicz, H.

    2016-04-01

    Using a table-top size soft X-ray (SXR) microscope, based on a laser plasma source with a double stream gas-puff target and a Fresnel zone plate objective, series of images of test samples were acquired. Characterization and optimization of the acquisition parameters were studied and evaluated in terms of signal to noise ratio (SNR). Conclusions for the optimization of SXR imaging were reached. Similar SNR measurements might be performed to characterize other SXR imaging systems as well. Software enabling live calculation of the SNR during the image acquisition might be introduced in future in the compact imaging systems for optimal image acquisition or for benchmarking purposes.

  1. Magnetic resonance imaging depiction of acquired Dyke-Davidoff-Masson syndrome with crossed cerebro-cerebellar diaschisis: Report of two cases

    Directory of Open Access Journals (Sweden)

    Ranjana Gupta

    2015-01-01

    Full Text Available Acquired Dyke-Davidoff-Masson syndrome, also known as hemispheric atrophy, is characterized by loss of volume of one cerebral hemisphere from an insult in early life. Crossed cerebellar diaschisis refers to dysfunction/atrophy of cerebellar hemisphere which is secondary to contralateral supratentorial insult. We describe magnetic resonance imaging findings in two cases of acquired Dyke-Davidoff-Masson syndrome with crossed cerebro-cerebellar diaschisis.

  2. Development of a single-shot CCD-based data acquisition system for time-resolved X-ray photoelectron spectroscopy at an X-ray free-electron laser facility

    International Nuclear Information System (INIS)

    A single-shot CCD-based data acquisition system for time-resolved photoelectron spectroscopy using an X-ray free-electron laser has been developed. The basic performance of the system is demonstrated using XFEL-induced and synchrotron-radiation-induced Ti 1s core-level spectroscopy. In order to utilize high-brilliance photon sources, such as X-ray free-electron lasers (XFELs), for advanced time-resolved photoelectron spectroscopy (TR-PES), a single-shot CCD-based data acquisition system combined with a high-resolution hemispherical electron energy analyzer has been developed. The system’s design enables it to be controlled by an external trigger signal for single-shot pump–probe-type TR-PES. The basic performance of the system is demonstrated with an offline test, followed by online core-level photoelectron and Auger electron spectroscopy in ‘single-shot image’, ‘shot-to-shot image (image-to-image storage or block storage)’ and ‘shot-to-shot sweep’ modes at soft X-ray undulator beamline BL17SU of SPring-8. In the offline test the typical repetition rate for image-to-image storage mode has been confirmed to be about 15 Hz using a conventional pulse-generator. The function for correcting the shot-to-shot intensity fluctuations of the exciting photon beam, an important requirement for the TR-PES experiments at FEL sources, has been successfully tested at BL17SU by measuring Au 4f photoelectrons with intentionally controlled photon flux. The system has also been applied to hard X-ray PES (HAXPES) in ‘ordinary sweep’ mode as well as shot-to-shot image mode at the 27 m-long undulator beamline BL19LXU of SPring-8 and also at the SACLA XFEL facility. The XFEL-induced Ti 1s core-level spectrum of La-doped SrTiO3 is reported as a function of incident power density. The Ti 1s core-level spectrum obtained at low power density is consistent with the spectrum obtained using the synchrotron source. At high power densities the Ti 1s core-level spectra show

  3. Development of a single-shot CCD-based data acquisition system for time-resolved X-ray photoelectron spectroscopy at an X-ray free-electron laser facility

    Energy Technology Data Exchange (ETDEWEB)

    Oura, Masaki, E-mail: oura@spring8.or.jp; Wagai, Tatsuya; Chainani, Ashish [RIKEN SPring-8 Center, 1-1-1 Kouto, Sayo-cho, Sayo-gun, Hyogo 679-5148 (Japan); Miyawaki, Jun [RIKEN SPring-8 Center, 1-1-1 Kouto, Sayo-cho, Sayo-gun, Hyogo 679-5148 (Japan); The University of Tokyo, 1-1-1 Kouto, Sayo-cho, Sayo-gun, Hyogo 679-5198 (Japan); Sato, Hiromi [RIKEN SPring-8 Center, 1-1-1 Kouto, Sayo-cho, Sayo-gun, Hyogo 679-5148 (Japan); Matsunami, Masaharu [RIKEN SPring-8 Center, 1-1-1 Kouto, Sayo-cho, Sayo-gun, Hyogo 679-5148 (Japan); The University of Tokyo, Kashiwanoha 5-1-5, Kashiwa, Chiba 277-8581 (Japan); Institute for Molecular Science, Myodaiji, Okazaki, Aichi 444-8585 (Japan); Eguchi, Ritsuko [RIKEN SPring-8 Center, 1-1-1 Kouto, Sayo-cho, Sayo-gun, Hyogo 679-5148 (Japan); The University of Tokyo, Kashiwanoha 5-1-5, Kashiwa, Chiba 277-8581 (Japan); Okayama University, Okayama 700-8530 (Japan); Kiss, Takayuki; Yamaguchi, Takashi; Nakatani, Yasuhiro [Osaka University, Toyonaka, Osaka 560-8531 (Japan); Togashi, Tadashi; Katayama, Tetsuo [JASRI, 1-1-1 Kouto, Sayo-cho, Sayo-gun, Hyogo 679-5198 (Japan); Ogawa, Kanade; Yabashi, Makina; Tanaka, Yoshihito; Kohmura, Yoshiki; Tamasaku, Kenji [RIKEN SPring-8 Center, 1-1-1 Kouto, Sayo-cho, Sayo-gun, Hyogo 679-5148 (Japan); Shin, Shik [RIKEN SPring-8 Center, 1-1-1 Kouto, Sayo-cho, Sayo-gun, Hyogo 679-5148 (Japan); The University of Tokyo, Kashiwanoha 5-1-5, Kashiwa, Chiba 277-8581 (Japan); Ishikawa, Tetsuya [RIKEN SPring-8 Center, 1-1-1 Kouto, Sayo-cho, Sayo-gun, Hyogo 679-5148 (Japan)

    2013-12-10

    A single-shot CCD-based data acquisition system for time-resolved photoelectron spectroscopy using an X-ray free-electron laser has been developed. The basic performance of the system is demonstrated using XFEL-induced and synchrotron-radiation-induced Ti 1s core-level spectroscopy. In order to utilize high-brilliance photon sources, such as X-ray free-electron lasers (XFELs), for advanced time-resolved photoelectron spectroscopy (TR-PES), a single-shot CCD-based data acquisition system combined with a high-resolution hemispherical electron energy analyzer has been developed. The system’s design enables it to be controlled by an external trigger signal for single-shot pump–probe-type TR-PES. The basic performance of the system is demonstrated with an offline test, followed by online core-level photoelectron and Auger electron spectroscopy in ‘single-shot image’, ‘shot-to-shot image (image-to-image storage or block storage)’ and ‘shot-to-shot sweep’ modes at soft X-ray undulator beamline BL17SU of SPring-8. In the offline test the typical repetition rate for image-to-image storage mode has been confirmed to be about 15 Hz using a conventional pulse-generator. The function for correcting the shot-to-shot intensity fluctuations of the exciting photon beam, an important requirement for the TR-PES experiments at FEL sources, has been successfully tested at BL17SU by measuring Au 4f photoelectrons with intentionally controlled photon flux. The system has also been applied to hard X-ray PES (HAXPES) in ‘ordinary sweep’ mode as well as shot-to-shot image mode at the 27 m-long undulator beamline BL19LXU of SPring-8 and also at the SACLA XFEL facility. The XFEL-induced Ti 1s core-level spectrum of La-doped SrTiO{sub 3} is reported as a function of incident power density. The Ti 1s core-level spectrum obtained at low power density is consistent with the spectrum obtained using the synchrotron source. At high power densities the Ti 1s core-level spectra

  4. Pixel Color Clustering of Multi-Temporally Acquired Digital Photographs of a Rice Canopy by Luminosity-Normalization and Pseudo-Red-Green-Blue Color Imaging

    OpenAIRE

    Ryoichi Doi; Chusnul Arif; Budi Indra Setiawan; Masaru Mizoguchi

    2014-01-01

    Red-green-blue (RGB) channels of RGB digital photographs were loaded with luminosity-adjusted R, G, and completely white grayscale images, respectively (RGwhtB method), or R, G, and R + G (RGB yellow) grayscale images, respectively (RGrgbyB method), to adjust the brightness of the entire area of multi-temporally acquired color digital photographs of a rice canopy. From the RGwhtB or RGrgbyB pseudocolor image, cyan, magenta, CMYK yellow, black, L*, a*, and b* grayscale images were prepared. Us...

  5. Investigation and identification of etiologies involved in the development of acquired hydronephrosis in aged laboratory mice with the use of high-frequency ultrasound imaging

    Directory of Open Access Journals (Sweden)

    Danielle A. Springer

    2014-08-01

    Full Text Available Laboratory mice develop naturally occurring lesions that affect biomedical research. Hydronephrosis is a recognized pathologic abnormality of the mouse kidney. Acquired hydronephrosis can affect any mouse, as it is caused by any naturally occurring disease that impairs free urine flow. Many etiologies leading to this condition are of particular significance to aging mice. Non-invasive ultrasound imaging detects renal pelvic dilation, renal enlargement, and parenchymal loss for pre-mortem identification of this condition. High-frequency ultrasound transducers produce high-resolution images of small structures, ideal for detecting organ pathology in mice. Using a 40 MHz linear array transducer, we obtained high-resolution images of a diversity of pathologic lesions occurring within the abdomen of seven geriatric mice with acquired hydronephrosis that enabled a determination of the underlying etiology. Etiologies diagnosed from the imaging results include pyelonephritis, neoplasia, urolithiasis, mouse urologic syndrome, and spontaneous hydronephrosis, and were confirmed at necropsy. A retrospective review of abdominal scans from an additional 149 aging mice shows that the most common etiologies associated with acquired hydronephrosis are mouse urologic syndrome and abdominal neoplasia. This report highlights the utility of high-frequency ultrasound for surveying research mice for age-related pathology, and is the first comprehensive report of multiple cases of acquired hydronephrosis in mice.

  6. Accurate IMRT fluence verification for prostate cancer patients using 'in-vivo' measured EPID images and in-room acquired kilovoltage cone-beam CT scans

    NARCIS (Netherlands)

    A.S.A.M. Ali (Ali Sid Ahmed M.); M.L.P. Dirkx (Maarten); R.M. Cools (Ruud); B.J.M. Heijmen (Ben)

    2013-01-01

    textabstractBackground: To investigate for prostate cancer patients the comparison of 'in-vivo' measured portal dose images (PDIs) with predictions based on a kilovoltage cone-beam CT scan (CBCT), acquired during the same treatment fraction, as an alternative for pre-treatment verification. For eval

  7. A model-based approach for detection of runways and other objects in image sequences acquired using an on-board camera

    Science.gov (United States)

    Kasturi, Rangachar; Devadiga, Sadashiva; Tang, Yuan-Liang

    1994-08-01

    This research was initiated as a part of the Advanced Sensor and Imaging System Technology (ASSIST) program at NASA Langley Research Center. The primary goal of this research is the development of image analysis algorithms for the detection of runways and other objects using an on-board camera. Initial effort was concentrated on images acquired using a passive millimeter wave (PMMW) sensor. The images obtained using PMMW sensors under poor visibility conditions due to atmospheric fog are characterized by very low spatial resolution but good image contrast compared to those images obtained using sensors operating in the visible spectrum. Algorithms developed for analyzing these images using a model of the runway and other objects are described in Part 1 of this report. Experimental verification of these algorithms was limited to a sequence of images simulated from a single frame of PMMW image. Subsequent development and evaluation of algorithms was done using video image sequences. These images have better spatial and temporal resolution compared to PMMW images. Algorithms for reliable recognition of runways and accurate estimation of spatial position of stationary objects on the ground have been developed and evaluated using several image sequences. These algorithms are described in Part 2 of this report. A list of all publications resulting from this work is also included.

  8. Acquired Techniques

    DEFF Research Database (Denmark)

    Lunde Nielsen, Espen; Halse, Karianne

    2013-01-01

    Acquired Techniques - a Leap into the Archive, at Aarhus School of Architecture. In collaboration with Karianne Halse, James Martin and Mika K. Friis. Following the footsteps of past travelers this is a journey into tools and techniques of the architectural process. The workshop will focus upon...

  9. Acquired blepharoptosis

    NARCIS (Netherlands)

    Oosterhuis, HJGH

    1996-01-01

    A review is given of the aetiology and possible treatment of acquired (non-congenital) blepharoptosis, which is a common but not specific sign of neurological disease: The diagnostic categories of upper eyelid drooping are scheduled as (a) pseudo-ptosis due to a local process or overactivity of eye

  10. A Sequential Aerial Triangulation Algorithm for Real-time Georeferencing of Image Sequences Acquired by an Airborne Multi-Sensor System

    Directory of Open Access Journals (Sweden)

    Kyoungah Choi

    2012-12-01

    Full Text Available Real-time image georeferencing is essential to the prompt generation of spatial information such as orthoimages from the image sequence acquired by an airborne multi-sensor system. It is mostly based on direct georeferencing using a GPS/INS system, but its accuracy is limited by the quality of the GPS/INS data. More accurate results can be acquired using traditional aerial triangulation (AT combined with GPS/INS data, which can be performed only as a post-processing method due to intense computational requirements. In this study, we propose a sequential AT algorithm that can produce accurate results comparable to those from the simultaneous AT algorithm in real time. Whenever a new image is added, the proposed algorithm rapidly performs AT with minimal computation at the current stage using the computational results from the previous stage. The experimental results show that the georeferencing of an image sequence at any stage took less than 0.1 s and its accuracy was determined within ± 5 cm on the estimated ground points, which is comparable to the results of simultaneous AT. This algorithm may be used for applications requiring real-time image georeferencing such as disaster monitoring and image-based navigation.

  11. Pixel Color Clustering of Multi-Temporally Acquired Digital Photographs of a Rice Canopy by Luminosity-Normalization and Pseudo-Red-Green-Blue Color Imaging

    Directory of Open Access Journals (Sweden)

    Ryoichi Doi

    2014-01-01

    Full Text Available Red-green-blue (RGB channels of RGB digital photographs were loaded with luminosity-adjusted R, G, and completely white grayscale images, respectively (RGwhtB method, or R, G, and R + G (RGB yellow grayscale images, respectively (RGrgbyB method, to adjust the brightness of the entire area of multi-temporally acquired color digital photographs of a rice canopy. From the RGwhtB or RGrgbyB pseudocolor image, cyan, magenta, CMYK yellow, black, L*, a*, and b* grayscale images were prepared. Using these grayscale images and R, G, and RGB yellow grayscale images, the luminosity-adjusted pixels of the canopy photographs were statistically clustered. With the RGrgbyB and the RGwhtB methods, seven and five major color clusters were given, respectively. The RGrgbyB method showed clear differences among three rice growth stages, and the vegetative stage was further divided into two substages. The RGwhtB method could not clearly discriminate between the second vegetative and midseason stages. The relative advantages of the RGrgbyB method were attributed to the R, G, B, magenta, yellow, L*, and a* grayscale images that contained richer information to show the colorimetrical differences among objects than those of the RGwhtB method. The comparison of rice canopy colors at different time points was enabled by the pseudocolor imaging method.

  12. Pixel color clustering of multi-temporally acquired digital photographs of a rice canopy by luminosity-normalization and pseudo-red-green-blue color imaging.

    Science.gov (United States)

    Doi, Ryoichi; Arif, Chusnul; Setiawan, Budi Indra; Mizoguchi, Masaru

    2014-01-01

    Red-green-blue (RGB) channels of RGB digital photographs were loaded with luminosity-adjusted R, G, and completely white grayscale images, respectively (RGwhtB method), or R, G, and R + G (RGB yellow) grayscale images, respectively (RGrgbyB method), to adjust the brightness of the entire area of multi-temporally acquired color digital photographs of a rice canopy. From the RGwhtB or RGrgbyB pseudocolor image, cyan, magenta, CMYK yellow, black, L*, a*, and b* grayscale images were prepared. Using these grayscale images and R, G, and RGB yellow grayscale images, the luminosity-adjusted pixels of the canopy photographs were statistically clustered. With the RGrgbyB and the RGwhtB methods, seven and five major color clusters were given, respectively. The RGrgbyB method showed clear differences among three rice growth stages, and the vegetative stage was further divided into two substages. The RGwhtB method could not clearly discriminate between the second vegetative and midseason stages. The relative advantages of the RGrgbyB method were attributed to the R, G, B, magenta, yellow, L*, and a* grayscale images that contained richer information to show the colorimetrical differences among objects than those of the RGwhtB method. The comparison of rice canopy colors at different time points was enabled by the pseudocolor imaging method. PMID:25302325

  13. A moving blocker-based strategy for simultaneous megavoltage and kilovoltage scatter correction in cone-beam computed tomography image acquired during volumetric modulated arc therapy

    International Nuclear Information System (INIS)

    Purpose: To evaluate a moving blocker-based approach in estimating and correcting megavoltage (MV) and kilovoltage (kV) scatter contamination in kV cone-beam computed tomography (CBCT) acquired during volumetric modulated arc therapy (VMAT). Methods and materials: During the concurrent CBCT/VMAT acquisition, a physical attenuator (i.e., “blocker”) consisting of equally spaced lead strips was mounted and moved constantly between the CBCT source and patient. Both kV and MV scatter signals were estimated from the blocked region of the imaging panel, and interpolated into the unblocked region. A scatter corrected CBCT was then reconstructed from the unblocked projections after scatter subtraction using an iterative image reconstruction algorithm based on constraint optimization. Experimental studies were performed on a Catphan® phantom and an anthropomorphic pelvis phantom to demonstrate the feasibility of using a moving blocker for kV–MV scatter correction. Results: Scatter induced cupping artifacts were substantially reduced in the moving blocker corrected CBCT images. Quantitatively, the root mean square error of Hounsfield units (HU) in seven density inserts of the Catphan phantom was reduced from 395 to 40. Conclusions: The proposed moving blocker strategy greatly improves the image quality of CBCT acquired with concurrent VMAT by reducing the kV–MV scatter induced HU inaccuracy and cupping artifacts

  14. Modelling temporal stability of EPI time series using magnitude images acquired with multi-channel receiver coils.

    OpenAIRE

    Chloe Hutton; Evelyne Balteau; Antoine Lutti; Oliver Josephs; Nikolaus Weiskopf

    2012-01-01

    In 2001, Krueger and Glover introduced a model describing the temporal SNR (tSNR) of an EPI time series as a function of image SNR (SNR(0)). This model has been used to study physiological noise in fMRI, to optimize fMRI acquisition parameters, and to estimate maximum attainable tSNR for a given set of MR image acquisition and processing parameters. In its current form, this noise model requires the accurate estimation of image SNR. For multi-channel receiver coils, this is not straightforwar...

  15. Series of aerial images over Quivira National Wildlife Refuge, acquired on September 27th and 29th, 1981

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This data set is of seven georeferenced aerial images taken over Quivira National Wildlife Refuge on September 27th and 29th, 1981. This data set is a clipped,...

  16. X-ray image processing software for computing object size and object location coordinates from acquired optical and x-ray images

    International Nuclear Information System (INIS)

    X-ray and Visible image data processing software has been developed in Visual Basic for real time online and offline image information processing for NDT and Medical Applications. Software computes two dimension image size parameters from its sharp boundary lines by raster scanning the image contrast data. Code accepts bit map image data and hunts for multiple tumors of different sizes that may be present in the image definition and then computes size of each tumor and locates its approximate center for registering its location coordinates. Presence of foreign metal and glass balls industrial product such as chocolate and other food items imaged out using x-ray imaging technique are detected by the software and their size and position co-ordinates are computed by the software. Paper discusses ways and means to compute size and coordinated of air bubble like objects present in the x-ray and optical images and their multiple existences in image of interest. (author)

  17. Development of a single-shot CCD-based data acquisition system for time-resolved X-ray photoelectron spectroscopy at an X-ray free-electron laser facility.

    Science.gov (United States)

    Oura, Masaki; Wagai, Tatsuya; Chainani, Ashish; Miyawaki, Jun; Sato, Hiromi; Matsunami, Masaharu; Eguchi, Ritsuko; Kiss, Takayuki; Yamaguchi, Takashi; Nakatani, Yasuhiro; Togashi, Tadashi; Katayama, Tetsuo; Ogawa, Kanade; Yabashi, Makina; Tanaka, Yoshihito; Kohmura, Yoshiki; Tamasaku, Kenji; Shin, Shik; Ishikawa, Tetsuya

    2014-01-01

    In order to utilize high-brilliance photon sources, such as X-ray free-electron lasers (XFELs), for advanced time-resolved photoelectron spectroscopy (TR-PES), a single-shot CCD-based data acquisition system combined with a high-resolution hemispherical electron energy analyzer has been developed. The system's design enables it to be controlled by an external trigger signal for single-shot pump-probe-type TR-PES. The basic performance of the system is demonstrated with an offline test, followed by online core-level photoelectron and Auger electron spectroscopy in 'single-shot image', 'shot-to-shot image (image-to-image storage or block storage)' and `shot-to-shot sweep' modes at soft X-ray undulator beamline BL17SU of SPring-8. In the offline test the typical repetition rate for image-to-image storage mode has been confirmed to be about 15 Hz using a conventional pulse-generator. The function for correcting the shot-to-shot intensity fluctuations of the exciting photon beam, an important requirement for the TR-PES experiments at FEL sources, has been successfully tested at BL17SU by measuring Au 4f photoelectrons with intentionally controlled photon flux. The system has also been applied to hard X-ray PES (HAXPES) in `ordinary sweep' mode as well as shot-to-shot image mode at the 27 m-long undulator beamline BL19LXU of SPring-8 and also at the SACLA XFEL facility. The XFEL-induced Ti 1s core-level spectrum of La-doped SrTiO3 is reported as a function of incident power density. The Ti 1s core-level spectrum obtained at low power density is consistent with the spectrum obtained using the synchrotron source. At high power densities the Ti 1s core-level spectra show space-charge effects which are analysed using a known mean-field model for ultrafast electron packet propagation. The results successfully confirm the capability of the present data acquisition system for carrying out the core-level HAXPES studies of condensed matter induced by the XFEL. PMID:24365935

  18. REGION-BASED 3D SURFACE RECONSTRUCTION USING IMAGES ACQUIRED BY LOW-COST UNMANNED AERIAL SYSTEMS

    Directory of Open Access Journals (Sweden)

    Z. Lari

    2015-08-01

    Full Text Available Accurate 3D surface reconstruction of our environment has become essential for an unlimited number of emerging applications. In the past few years, Unmanned Aerial Systems (UAS are evolving as low-cost and flexible platforms for geospatial data collection that could meet the needs of aforementioned application and overcome limitations of traditional airborne and terrestrial mobile mapping systems. Due to their payload restrictions, these systems usually include consumer-grade imaging and positioning sensor which will negatively impact the quality of the collected geospatial data and reconstructed surfaces. Therefore, new surface reconstruction surfaces are needed to mitigate the impact of using low-cost sensors on the final products. To date, different approaches have been proposed to for 3D surface construction using overlapping images collected by imaging sensor mounted on moving platforms. In these approaches, 3D surfaces are mainly reconstructed based on dense matching techniques. However, generated 3D point clouds might not accurately represent the scanned surfaces due to point density variations and edge preservation problems. In order to resolve these problems, a new region-based 3D surface renostruction trchnique is introduced in this paper. This approach aims to generate a 3D photo-realistic model of individually scanned surfaces within the captured images. This approach is initiated by a Semi-Global dense Matching procedure is carried out to generate a 3D point cloud from the scanned area within the collected images. The generated point cloud is then segmented to extract individual planar surfaces. Finally, a novel region-based texturing technique is implemented for photorealistic reconstruction of the extracted planar surfaces. Experimental results using images collected by a camera mounted on a low-cost UAS demonstrate the feasibility of the proposed approach for photorealistic 3D surface reconstruction.

  19. Region-Based 3d Surface Reconstruction Using Images Acquired by Low-Cost Unmanned Aerial Systems

    Science.gov (United States)

    Lari, Z.; Al-Rawabdeh, A.; He, F.; Habib, A.; El-Sheimy, N.

    2015-08-01

    Accurate 3D surface reconstruction of our environment has become essential for an unlimited number of emerging applications. In the past few years, Unmanned Aerial Systems (UAS) are evolving as low-cost and flexible platforms for geospatial data collection that could meet the needs of aforementioned application and overcome limitations of traditional airborne and terrestrial mobile mapping systems. Due to their payload restrictions, these systems usually include consumer-grade imaging and positioning sensor which will negatively impact the quality of the collected geospatial data and reconstructed surfaces. Therefore, new surface reconstruction surfaces are needed to mitigate the impact of using low-cost sensors on the final products. To date, different approaches have been proposed to for 3D surface construction using overlapping images collected by imaging sensor mounted on moving platforms. In these approaches, 3D surfaces are mainly reconstructed based on dense matching techniques. However, generated 3D point clouds might not accurately represent the scanned surfaces due to point density variations and edge preservation problems. In order to resolve these problems, a new region-based 3D surface renostruction trchnique is introduced in this paper. This approach aims to generate a 3D photo-realistic model of individually scanned surfaces within the captured images. This approach is initiated by a Semi-Global dense Matching procedure is carried out to generate a 3D point cloud from the scanned area within the collected images. The generated point cloud is then segmented to extract individual planar surfaces. Finally, a novel region-based texturing technique is implemented for photorealistic reconstruction of the extracted planar surfaces. Experimental results using images collected by a camera mounted on a low-cost UAS demonstrate the feasibility of the proposed approach for photorealistic 3D surface reconstruction.

  20. First results for an image processing workflow for hyperspatial imagery acquired with a low-cost unmanned aerial vehicle (UAV).

    Science.gov (United States)

    Very high-resolution images from unmanned aerial vehicles (UAVs) have great potential for use in rangeland monitoring and assessment, because the imagery fills the gap between ground-based observations and remotely sensed imagery from aerial or satellite sensors. However, because UAV imagery is ofte...

  1. Simple luminosity normalization of greenness, yellowness and redness/greenness for comparison of leaf spectral profiles in multi-temporally acquired remote sensing images

    Indian Academy of Sciences (India)

    Ryoichi Doi

    2012-09-01

    Observation of leaf colour (spectral profiles) through remote sensing is an effective method of identifying the spatial distribution patterns of abnormalities in leaf colour, which enables appropriate plant management measures to be taken. However, because the brightness of remote sensing images varies with acquisition time, in the observation of leaf spectral profiles in multi-temporally acquired remote sensing images, changes in brightness must be taken into account. This study identified a simple luminosity normalization technique that enables leaf colours to be compared in remote sensing images over time. The intensity values of green and yellow (green+red) exhibited strong linear relationships with luminosity (R2 > 0.926) when various invariant rooftops in Bangkok or Tokyo were spectral-profiled using remote sensing images acquired at different time points. The values of the coefficient and constant or the coefficient of the formulae describing the intensity of green or yellow were comparable among the single Bangkok site and the two Tokyo sites, indicating the technique’s general applicability. For single rooftops, the values of the coefficient of variation for green, yellow, and red/green were 16% or less (n=6−11), indicating an accuracy not less than those of well-established remote sensing measures such as the normalized difference vegetation index. After obtaining the above linear relationships, raw intensity values were normalized and a temporal comparison of the spectral profiles of the canopies of evergreen and deciduous tree species in Tokyo was made to highlight the changes in the canopies’ spectral profiles. Future aspects of this technique are discussed herein.

  2. PET imaging of HSV1-tk mutants with acquired specificity toward pyrimidine- and acycloguanosine-based radiotracers

    International Nuclear Information System (INIS)

    The aim of this study was to create an alternative mutant of the herpes simplex virus type 1 thymidine kinase (HSV1-tk) reporter gene with reduced phosphorylation capacity for acycloguanosine derivatives, but not pyrimidine-based compounds that will allow for successful PET imaging. A new mutant of HSV1-tk reporter gene, suitable for PET imaging using pyrimidine-based radiotracers, was developed. The HSV1-tk mutant contains an arginine-to-glutamine substitution at position 176 (HSV1-R176Qtk) of the nucleoside binding region of the enzyme. The mutant-gene product showed favorable enzymatic characteristics toward pyrimidine-based nucleosides, while exhibiting reduced activity with acycloguanosine derivatives. In order to enhance HSV1-R176Qtk reporter activity with pyrimidine-based radiotracers, we introduced the R176Q substitution into the more active HSV1-sr39tk mutant. U87 human glioma cells transduced with the HSV1-R176Qsr39tk double mutant reporter gene showed high 3H-FEAU pyrimidine nucleoside and low 3H-penciclovir acycloguanosine analog uptake in vitro. PET imaging also demonstrated high 18F-FEAU and low 18F-FHBG accumulation in HSV1-R176Qsr39tk+ xenografts. The feasibility of imaging two independent nucleoside-specific HSV1-tk mutants in the same animal with PET was demonstrated. Two opposite xenografts expressing the HSV1-R176Qsr39tk reporter gene and the previously described acycloguanosine-specific mutant of HSV1-tk, HSV1-A167Ysr39tk reporter gene, were imaged using a short-lived pyrimidine-based 18F-FEAU and an acycloguanosine-based 18F-FHBG radiotracer, respectively, administered on 2 consecutive days. We conclude that in combination with acycloguanosine-specific HSV1-A167Ysr39tk reporter gene, a HSV1-tk mutant containing the R176Q substitution could be used for PET imaging of two different cell populations or concurrent molecular biological processes in the same living subject. (orig.)

  3. Crosstalk analysis of simultaneously acquired dual-isotope 201tl myocardial perfusion SPECT and 99Tcm-RBC equilibrium ventricle imaging

    International Nuclear Information System (INIS)

    Objective: To analysis the crosstalk between the 20'1Tl and 99Tcm while the myocardial SPECT imaging with 201Tl and the equilibrium ventricle imaging with 99Tcm-RBC are simultaneously acquired, and to search after a method to reduce the down scatter of 99Tcm in the 201Tl window. Methods: Myocardial perfusion images were acquired using a cardiac phantom, which can present various levels of ischemia. The pulse height analysis was performed before the SPECT acquisition. The down scatter ratio of different 201Tl doses was calculated on each project with variable acquisition energy window. After the raw data were reconstructed with Butterworth filter, the defect-to-myocardium count ratios from different 201Tl acquisition window and variable defect levels were compared. Results: During the dual-isotope acquisition with 201Tl and 99Tcm the main crosstalk was the down scatter of 99Tcm in 201Tl window, which was considerably reduced while using higher dosage of 201Tl. The down scatter was also inhibited by applying more specific energy window of 201Tl. The defect-to-myocardium ratio analysis showed that only the data acquired under 15% energy window were affected on the contrast of the defects in short axis slice. The window of 201Tl and the extent of the ischemia influenced the defect-to-myocardium ratios of mimic ischemia segments differently. The completely defect group appeared insensible to the change of acquisition window. Between the defect-to-myocardium ratio of 33% filled group and the 66% filled group considerable difference was demonstrated while the acquisition window of 20% was used. Conclusions: The down scatter of 99Tcm is the major factor which influences the simultaneous dual-isotope acquisition. The stain can be reduced either using more specific 201Tl energy acquisition window or applying higher dosage of 201Tl. But due to the long half-life of 201Tl, the authors can not increase the dosage discretionarily. As the more specific window of 201Tl can avoid

  4. Accurate IMRT fluence verification for prostate cancer patients using ‘in-vivo’ measured EPID images and in-room acquired kilovoltage cone-beam CT scans

    International Nuclear Information System (INIS)

    To investigate for prostate cancer patients the comparison of ‘in-vivo’ measured portal dose images (PDIs) with predictions based on a kilovoltage cone-beam CT scan (CBCT), acquired during the same treatment fraction, as an alternative for pre-treatment verification. For evaluation purposes, predictions were also performed using the patients’ planning CTs (pCT). To get reliable CBCT electron densities for PDI predictions, Hounsfield units from the pCT were mapped onto the CBCT, while accounting for non-rigidity in patient anatomy in an approximate way. PDI prediction accuracy was first validated for an anatomical phantom, using IMRT treatment plans of ten prostate cancer patients. Clinical performance was studied using data acquired for 50 prostate cancer patients. For each patient, 4–5 CBCTs were available, resulting in a total of 1413 evaluated images. Measured and predicted PDIs were compared using γ-analyses with 3% global dose difference and 3 mm distance to agreement as reference criteria. Moreover, the pass rate for automated PDI comparison was assessed. To quantify improvements in IMRT fluence verification accuracy results from multiple fractions were combined by generating a γ-image with values halfway the minimum and median γ values, pixel by pixel. For patients, CBCT-based PDI predictions showed a high agreement with measurements, with an average percentage of rejected pixels of 1.41% only. In spite of possible intra-fraction motion and anatomy changes, this was only slightly larger than for phantom measurements (0.86%). For pCT-based predictions, the agreement deteriorated (average percentage of rejected pixels 2.98%), due to an enhanced impact of anatomy variations. For predictions based on CBCT, combination of the first 2 fractions yielded gamma results in close agreement with pre-treatment analyses (average percentage of rejected pixels 0.63% versus 0.35%, percentage of rejected beams 0.6% versus 0%). For the pCT-based approach, only

  5. An automated computerized methodology for the segmentation of in vivo acquired DSA images: application in the New Zealand hindlimb ischemia model

    International Nuclear Information System (INIS)

    In-vivo dynamic visualization and accurate quantification of vascular networks is a prerequisite of crucial importance in both therapeutic angiogenesis and tumor anti-angiogenesis studies. A user independent computerized tool was developed, for the automated segmentation and quantitative assessment of in-vivo acquired DSA images. Automatic vessel assessment was performed employing the concept of image structural tensor. Initially, vasculature was estimated according to the largest eigenvalue of the structural tensor. The resulted eigenvalue matrix was treated as gray-matrix from which the vessels were gradually segmented and then categorized in three main sub-groups; large, medium and small-size vessels. The histogram percentiles, corresponding to 85%, 65% and 47% of prime eigenvalue gray-matrix were optimally found to give the thresholds T1, T2 and T3 respectively, for extracting vessels of different size. The proposed methodology was tested on a series of DSA images in both normal rabbits (group A) and in rabbits with experimental induced chronic hindlimb ischemia (group B). As a result an automated computerized tool was developed to process images without any user intervention in either experimental or clinical studies. Specifically, a higher total vascular area and length were calculated in group B compared to group A (p=0.0242 and p=0.0322 respectively), which is in accordance to the fact that significantly more collateral arteries are developed during the physiological response to the stimuli of ischemia.

  6. External scintigraphy in monitoring the behavior of pharmaceutical formulations in vivo I: technique for acquiring high-resolution images of tablets

    International Nuclear Information System (INIS)

    A new method for monitoring tablet disintegration in vivo was developed. In this method, the tablets were labeled with a short-lived radionuclide, technetium 99m, and monitored by a gamma camera. Several innovations were introduced with this method. First, computer reconstruction algorithms were used to enhance the scintigraphic images of the disintegrating tablet in vivo. Second, the use of a four-pinhole collimator to acquire multiple views of the tablet resulted in high count rates and reduced acquisition times of the scintigraphic images. Third, the magnification of the scintigraphic images achieved by pinhole collimation led to significant improvement in resolution. Fourth, the radioinuclide was incorporated into the granulation so that the whole mass of the tablet was uniformly labeled with high levels of activity. This technique allowed the continuous monitoring of the disintegration process of tablets in vivo in experimental animals. Multiple pinhole collimation and the labeling process permitted the acquisition of quality scintigraphic images of the labeled tablet every 30 sec. The resolution of the method was tested in vitro and in vivo

  7. Analysis of the quality of image data acquired by the LANDSAT-4 thematic mapper and multispectral scanners. [Central Valley, California

    Science.gov (United States)

    Colwell, R. N. (Principal Investigator)

    1983-01-01

    Image products and numeric data were extracted from both TM and MSS data in an effort to evaluate the quality of these data for interpreting major agricultural resources and conditions in California's Central Valley. The utility of TM data appears excellent for meeting most of the inventory objectives of the agricultural resource specialist. These data should be extremely valuable for crop type and area proportion estimation, for updating agricultural land use survey maps at 1:24,000-scale and smaller, for field boundary definition, and for determining the size and location of individual farmsteads.

  8. Analysis of the quality of image data acquired by the LANDSAT-4 thematic mapper and multispectral scanners. [Plumas County, California

    Science.gov (United States)

    Colwell, R. N. (Principal Investigator)

    1984-01-01

    A seven step procedure developed for evaluating the geometric properties of MSS and TM film produces is being implemented. Some 476 control points were selected of which 238 are being tested and edited for digitization and scaling errors. Tables show statistics established for assessing the spectral characteristics and variability, as well as the spatial resolution and radiometric sensitivity of TM data for a forest environment in an effort to determine the extent to which major forest cover type can be detected and identified on TM digital and image products. Results thus far show that the high quality obtained are more than sufficient for meeting most of the inventory objectives of the renewable resource specialist. The TM data should be extremely valuable for: (1) estimating forest cover types; (2) updating land use survey maps; and (3) determining the size and shape and location of individual forest clearings and water resources.

  9. Analysis of the quality of image data acquired by the LANDSAT-4 Thematic Mapper and Multispectral Scanners

    Science.gov (United States)

    Colwell, R. N. (Principal Investigator)

    1984-01-01

    The geometric quality of TM film and digital products is evaluated by making selective photomeasurements and by measuring the coordinates of known features on both the TM products and map products. These paired observations are related using a standard linear least squares regression approach. Using regression equations and coefficients developed from 225 (TM film product) and 20 (TM digital product) control points, map coordinates of test points are predicted. The residual error vectors and analysis of variance (ANOVA) were performed on the east and north residual using nine image segments (blocks) as treatments. Based on the root mean square error of the 223 (TM film product) and 22 (TM digital product) test points, users of TM data expect the planimetric accuracy of mapped points to be within 91 meters and within 117 meters for the film products, and to be within 12 meters and within 14 meters for the digital products.

  10. TU-C-12A-07: Characterization of Longitudinal Reproducibility of Quantitative Diffusion Imaging Data Acquired with Four Different Protocols Using a Phantom

    International Nuclear Information System (INIS)

    Purpose: To characterize and compare the longitudinal reproducibility of diffusion imaging data acquired with four different protocols using a phantom. Methods: The Diffusive Quantitative Imaging Phantom (DQIP) was constructed using fifteen cylindrical compartments within a larger compartment, filled with deionized water doped with CuSO4 and NaCl. The smaller compartments contained arrays of hexagonal or cylindrical glass capillaries of varying inner diameters, for differing restraint of water diffusion. The sensitivity of diffusion imaging metrics to signal-to-noise ratio (SNR) was probed by doping compartments with differing ratios of deuterium oxide to H2O. A cork phantom enclosure was constructed to increase thermal stability during scanning and a cork holder was made to reproduce scanner positioning. Four different protocols of DWI (diffusion weighted imaging) and DTI (Diffusion tensor imaging) imaging were assembled on a GE Excite HDx 3.0T MRI scanner to collect imaging data over 9-10 days. Data was processed with in-house software created in Matlab to obtain fractional anisotropy (FA) and apparent diffusion coefficient (ADC) values. Results: All DTI and DWI sequences showed good longitudinal stability of mean FA and ADC values per compartment, exhibiting low standard deviation ∼9%. A t-test was performed to compare mean FA values from the DTI clinical protocol to those of the DTI special protocol, indicating significantly different values in the majority of compartments. ANOVA performed on ADC values for all DTI and DWI sequences also showed significantly different values in a majority of compartments. Conclusion: This work has the potential for quantifying systemic variations between diffusion imaging sequences from different platforms. Characterization of DWI and DTI performance were done over four sequences with predictable results. This data suggests that the DQIP phantom may be a reliable method of monitoring day-to-day and scan-to-scan variation in

  11. Non-destructive assay employing 2D and 3D digital radiographic imaging acquired with thermal neutrons and reactor-produced radioisotopes

    International Nuclear Information System (INIS)

    The inner structure of some objects can only be visualized by using suitable techniques, when safety reasons or expensive costs preclude the application of invasive procedures. The kind of agent rendering an object partially transparent, unveiling thus its features, depends upon the object size and composition. As a rough rule of thumb, light materials are transparent to gamma and X-rays while the heavy ones are transparent to neutrons. When, after traversing an object, they hit a proper 2-D detector, a radiograph is produced representing a convoluted cross section, called projection, of that object. Taking a large number of such projections for different object attitudes, it is possible to obtain a 3-D tomography of the object as a map of attenuation coefficients. This procedure however, besides a time-consuming task, requires specially tailored equipment and software, not always available or affordable. Yet, in some circumstances it is feasible to replace the 3-D tomography by a stereoscopy, allowing one to visualize the spatial configuration of the object under analysis. In this work, 2-D and 3-D radiographic images have been acquired using thermal neutrons and reactor-produced radioisotopes and proper imaging plates as detectors. The stereographic vision has been achieved by taking two radiographs of the same object at different angles, from the detector point of view. After a treatment to render them red-white and green-white they were properly merged to yield a single image capable to be watched with red-green glasses. All the image treatment and rendering has been performed with the software ImageJ. (author)

  12. A comparison of the precision of three-dimensional images acquired by 2 digital intraoral scanners: effects of tooth irregularity and scanning direction

    Science.gov (United States)

    Anh, Ji-won; Park, Ji-Man; Chun, Youn-Sic; Kim, Miae

    2016-01-01

    Objective The purpose of this study was to compare the precision of three-dimensional (3D) images acquired using iTero® (Align Technology Inc., San Jose, CA, USA) and Trios® (3Shape Dental Systems, Copenhagen, Denmark) digital intraoral scanners, and to evaluate the effects of the severity of tooth irregularities and scanning sequence on precision. Methods Dental arch models were fabricated with differing degrees of tooth irregularity and divided into 2 groups based on scanning sequence. To assess their precision, images were superimposed and an optimized superimposition algorithm was employed to measure any 3D deviation. The t-test, paired t-test, and one-way ANOVA were performed (p < 0.05) for statistical analysis. Results The iTero® and Trios® systems showed no statistically significant difference in precision among models with differing degrees of tooth irregularity. However, there were statistically significant differences in the precision of the 2 scanners when the starting points of scanning were different. The iTero® scanner (mean deviation, 29.84 ± 12.08 µm) proved to be less precise than the Trios® scanner (22.17 ± 4.47 µm). Conclusions The precision of 3D images differed according to the degree of tooth irregularity, scanning sequence, and scanner type. However, from a clinical standpoint, both scanners were highly accurate regardless of the degree of tooth irregularity. PMID:26877977

  13. Acquired cystic kidney disease

    Energy Technology Data Exchange (ETDEWEB)

    Choyke, P.L. [National Institutes of Health, Bethesda, MD (United States). Dept. of Diagnostic Radiology

    2000-11-01

    Acquired cystic kidney disease (ACKD), also known as acquired renal cystic disease (ARCD,) occurs in patients who are on dialysis for end-stage renal disease. It is generally accepted that ACKD develops as a consequence of sustained uremia and can first manifest even before dialysis is initiated while the patient is still in chronic renal failure. The role of immune suppression, particularly in transplant recipients, in the development of ACKD, is still under investigation. The prevalence of ACKD is directly related to the duration of dialysis and the risk of cancer is directly related to the presence of cysts. Herein we review the current understanding of the pathophysiology and imaging implications of ACKD. (orig.)

  14. Acquired cystic kidney disease

    International Nuclear Information System (INIS)

    Acquired cystic kidney disease (ACKD), also known as acquired renal cystic disease (ARCD,) occurs in patients who are on dialysis for end-stage renal disease. It is generally accepted that ACKD develops as a consequence of sustained uremia and can first manifest even before dialysis is initiated while the patient is still in chronic renal failure. The role of immune suppression, particularly in transplant recipients, in the development of ACKD, is still under investigation. The prevalence of ACKD is directly related to the duration of dialysis and the risk of cancer is directly related to the presence of cysts. Herein we review the current understanding of the pathophysiology and imaging implications of ACKD. (orig.)

  15. Computed tomography and magnetic resonance imaging of acquired abnormalities of the inner ear and cerebello-pontine angle; CT und MRT erworbener Veraenderungen des Innenohrs und Kleinhirnbrueckenwinkels

    Energy Technology Data Exchange (ETDEWEB)

    Grampp, S.; Czerny, C.; Henk, C.B.; Imhof, H. [Abteilung fuer Osteologie, Univ.-Klinik fuer Radiodiagnostik, Wien (Austria); Gstoettner, W. [Univ.-Klinik fuer Hals-Nasen-Ohren-Heilkunde, Frankfurt/Main (Germany)

    2003-03-01

    CT and MRI of acquired abnormalities of the inner ear and cerebello-pontine angle present themselves with very typical findings. The imaging should be adapted to the pathology looked for and either CT or MRI should be used alone or in combination.CT, especially high resolution CT (HRCT), provides an excellent bone contrast, while MRI has a much superior soft tissue contrast. Acute inflammatory changes of the inner ear are solely depicted by contrast-enhanced MRI. HRCT excellently depicts osseous changes of the inner ear and cerebellopontine angle such as chronic ossifying labyrinthitis occurring after acute labyrinthitis, otosclerotic or traumatic changes. Tumorous changes not yielding to bony changes are best delineated by MRI. Posttraumatic hemorrhage and chronic fibrotic changes within the labyrinth are depicted by MRI, only. In conclusion HRCT and MRI are excellent methods to delineate acquired abnormalities of the inner ear and cerebello-pontine angle. HRCT best depicts osseous changes while MRI best depicts soft tissue changes. HRCT and MRI are not concurrent methods but should better be used as complementary methods for imaging acquired abnormalities of inner ear and cerebellopontine angle. (orig.) [German] Bei erworbenen Veraenderungen des Innenohrs und der Kleinhirnbrueckenwinkelregion zeigen CT und MRT typische Bildcharakteristika, wobei die Bildgebung der zu suchenden Veraenderung angepasst werden sollte. Die CT liefert hochaufloesend (HRCT) einen exzellenten Knochen-, die MRT einen hervorragenden Weichteilkontrast. Akute entzuendliche Veraenderungen sind in der HRCT nicht erkennbar, sondern nur in der kontrastmittelverstaerkten MRT. Die HRCT erfasst am besten knoecherne Veraenderungen wie Ossifikationen des membranoesen Labyrinths im Rahmen einer chronischen Entzuendung, otosklerotische und traumatische Veraenderungen - selbst wenn diese nur diskret sind. Tumoroese Veraenderungen, die zu keiner ossaeren Veraenderung fuehren wie kleine Schwannome sowie

  16. Enhancing the quality of radiographic images acquired with point-like gamma-ray sources through correction of the beam divergence and attenuation

    International Nuclear Information System (INIS)

    Radiographic images acquired with point-like gamma-ray sources exhibit a desirable low penumbra effects specially when positioned far away from the set object-detector. Such an arrangement frequently is not affordable due to the limited flux provided by a distant source. A closer source, however, has two main drawbacks, namely the degradation of the spatial resolution - as actual sources are only approximately punctual - and the non-homogeneity of the beam hitting the detector, which creates a false attenuation map of the object being inspected. This non-homogeneity is caused by the beam divergence itself and by the different thicknesses traversed the beam even if the object were an homogeneous flat plate. In this work, radiographic images of objects with different geometries, such as flat plates and pipes have undergone a correction of beam divergence and attenuation addressing the experimental verification of the capability and soundness of an algorithm formerly developed to generate and process synthetic images. The impact of other parameters, including source-detector gap, attenuation coefficient, ratio defective-to-main hull thickness and counting statistics have been assessed for specifically tailored test-objects aiming at the evaluation of the ability of the proposed method to deal with different boundary conditions. All experiments have been carried out with an X-ray sensitive Imaging Plate and reactor-produced 198Au and 165Dy sources. The results have been compared with other technique showing a better capability to correct the attenuation map of inspected objects unveiling their inner structure otherwise concealed by the poor contrast caused by the beam divergence and attenuation, in particular for those regions far apart from the vertical of the source

  17. Clinical Evaluation of Spatial Accuracy of a Fusion Imaging Technique Combining Previously Acquired Computed Tomography and Real-Time Ultrasound for Imaging of Liver Metastases

    International Nuclear Information System (INIS)

    Purpose: This study was designed to evaluate the spatial accuracy of matching volumetric computed tomography (CT) data of hepatic metastases with real-time ultrasound (US) using a fusion imaging system (VNav) according to different clinical settings. Methods: Twenty-four patients with one hepatic tumor identified on enhanced CT and US were prospectively enrolled. A set of three landmarks markers was chosen on CT and US for image registration. US and CT images were then superimposed using the fusion imaging display mode. The difference in spatial location between the tumor visible on the CT and the US on the overlay images (reviewer no. 1, comment no. 2) was measured in the lateral, anterior–posterior, and vertical axis. The maximum difference (Dmax) was evaluated for different predictive factors.CT performed 1–30 days before registration versus immediately before. Use of general anesthesia for CT and US versus no anesthesia.Anatomic landmarks versus landmarks that include at least one nonanatomic structure, such as a cyst or a calcificationResultsOverall, Dmax was 11.53 ± 8.38 mm. Dmax was 6.55 ± 7.31 mm with CT performed immediately before VNav versus 17.4 ± 5.18 with CT performed 1–30 days before (p < 0.0001). Dmax was 7.05 ± 6.95 under general anesthesia and 16.81 ± 6.77 without anesthesia (p < 0.0015). Landmarks including at least one nonanatomic structure increase Dmax of 5.2 mm (p < 0.0001). The lowest Dmax (1.9 ± 1.4 mm) was obtained when CT and VNav were performed under general anesthesia, one immediately after the other. Conclusions: VNav is accurate when adequate clinical setup is carefully selected. Only under these conditions (reviewer no. 2), liver tumors not identified on US can be accurately targeted for biopsy or radiofrequency ablation using fusion imaging.

  18. Borehole-explosion and air-gun data acquired in the 2011 Salton Seismic Imaging Project (SSIP), southern California: description of the survey

    Science.gov (United States)

    Rose, Elizabeth J.; Fuis, Gary S.; Stock, Joann M.; Hole, John A.; Kell, Annie M.; Kent, Graham; Driscoll, Neal W.; Goldman, Mark; Reusch, Angela M.; Han, Liang; Sickler, Robert R.; Catchings, Rufus D.; Rymer, Michael J.; Criley, Coyn J.; Scheirer, Daniel S.; Skinner, Steven M.; Slayday-Criley, Coye J.; Murphy, Janice M.; Jensen, Edward G.; McClearn, Robert; Ferguson, Alex J.; Butcher, Lesley A.; Gardner, Max A.; Emmons, Iain; Loughran, Caleb L.; Svitek, Joseph R.; Bastien, Patrick C.; Cotton, Joseph A.; Croker, David S.; Harding, Alistair J.; Babcock, Jeffrey M.; Harder, Steven H.; Rosa, Carla M.

    2013-01-01

    earthquake energy can travel through the sediments. All of these factors determine how hard the earth will shake during a major earthquake. If we can improve on our understanding of how and where earthquakes will occur, and how strong their resultant shaking will be, then buildings can be designed or retrofitted accordingly in order to resist damage and collapse, and emergency plans can be adequately prepared. In addition, SSIP will investigate the processes of rifting and magmatism in the Salton Trough in order to better understand this important plate-boundary region. The Salton Trough is a unique rift in that subsidence is accompanied by huge influxes of infilling sediment from the Colorado River. Volcanism that accompanies the subsidence here is muted by these influxes of sediment. The Salton Trough, in the central part of the Imperial Valley, is apparently made up of entirely new crust: young sediment in the upper crust and basaltic intrusive rocks in the mid-to-lower crust (Fuis and others, 1984). Similar to the ultrasound and computed tomography (CT) scans performed by the medical industry, seismic imaging is a collection of techniques that enable scientists to obtain a picture of what is underground. The petroleum industry routinely uses these techniques to search for oil and gas at relatively shallow depths; however, the scope of this project demanded that we image as much as 30 km into the Earth’s crust. This project generated and recorded seismic waves, similar to sound waves, which move downward into the Earth and are bent (refracted) or echoed (reflected) back to the surface. SSIP acquired data in a series of intersecting lines that cover key areas of the Salton Trough. The sources of sound waves were detonations (shots) in deep boreholes, designed to create energy equivalent to magnitude 1–2 earthquakes. The study region routinely experiences earthquakes of these magnitudes, but earthquakes are not located in such a way as to permit us to create the

  19. Hospital-acquired pneumonia

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/000146.htm Hospital-acquired pneumonia To use the sharing features on this page, please enable JavaScript. Hospital-acquired pneumonia is an infection of the lungs ...

  20. Full-waveform inversion of multi-offset GPR data acquired in a vineyard to image and monitor soil water content

    Science.gov (United States)

    Lambot, Sébastien; André, Frédéric; Saussez, Stéphanie; van Durmen, Renaud; Delvaux, Bruno; van Leeuwen, Cornelis; Vereecken, Harry

    2010-05-01

    Sustainable and optimal agricultural and environmental management of water and land resources particularly relies on the description and understanding of soil water distribution and dynamics at the field scale. Knowledge of soil water content is essential in a vineyard, where it plays a crucial role in determining the wine quality through adequate water stresses. Yet, the inherent spatiotemporal variability of soil water content makes it difficult to assess at relevant scales and resolutions. In that respect, ground penetrating radar (GPR) has proven to be a useful geophysical tool to image the shallow subsurface and estimate its water content at the field scale. Traditional GPR techniques for soil water content estimation are usually based on strongly simplifying assumptions regarding electromagnetic wave propagation phenomena, which inherently leads to estimation errors and does not permit to account for the whole information content in the radar data. We developed a multi-offset full-waveform GPR model, which resorts to an exact solution of Maxwell's equations for wave propagating in multilayered media and a transfer function model describing the radar-antenna system and its interactions with the soil. The model is iteratively inverted using the global multilevel coordinate search algorithm to reconstruct the soil property profiles. The method was applied in a vineyard in south of France (Saint-Emilion) over an area of about 30 ha during summer 2009, resulting in about 1 million waveforms. The GPR system consisted in a time-domain GPR with two bistatic ground-coupled antennas, thereby resulting in two simultaneous offsets, with a center frequency of 400 MHz. Time-lapse measurements were also acquired after a precipitation event, and the data were inverted by coupling the GPR model to a soil hydrodynamic model. The results were consistent with field observations and electromagnetic induction measurements, thereby demonstrating the promising perspectives of the

  1. Imaging of acquired cystic disease-associated renal cell carcinoma by contrast-enhanced ultrasonography with perflubutane microbubbles and positron emission tomography-computed tomography.

    Science.gov (United States)

    Ishikawa, Isao; Morita, Kyoko; Hayama, Satoshi; Nakazawa, Tetsuya; Araki, Ichiro; Higashi, Kotaro; Miyazawa, Katsuhito; Suzuki, Koji; Nojima, Takayuki

    2011-02-01

    The preoperative assessment of renal cell carcinoma (RCC) complicated with acquired renal cystic disease in a 63-year-old male patient on long-term hemodialysis (30 years and 8 months) that was difficult because of no or poor contrast enhancement by dynamic CT scan is reported. Contrast-enhanced ultrasonography with perflubutane microbubbles and positron emission tomography-computed tomography (PET-CT) with 18F-fluorodeoxy glucose (FDG) in addition to dynamic CT were effective and useful for preoperative assessment of this patient. The pathological subtype of RCC in this patient was acquired cystic disease-associated RCC (ACD-associated RCC), which has been newly defined by Tickoo et al. (Am J Surg Pathol 30:141-153, 2006). PMID:20824295

  2. Cardiovascular Magnetic Resonance Imaging in the Assessment of Myocardial Blood Flow, Viability, and Diffuse Fibrosis in Congenital and Acquired Heart Disease

    OpenAIRE

    Pham, Hoang Minh

    2014-01-01

    Myocardial ischemia may occur after surgical correction of congenital heart defects involving the coronary arteries, in patients with congenital coronary artery anomalies, or in acquired heart disease. To assess myocardial ischemia disease in children, we used cardiac MRI as a non-invasive and radiation-free method to evaluate myocardial perfusion, viability, diffuse myocardial fibrosis, and heart function, to guide further therapy and for a better understanding of the pathophysiology of the ...

  3. Point Cloud Generation from Aerial Image Data Acquired by a Quadrocopter Type Micro Unmanned Aerial Vehicle and a Digital Still Camera

    Science.gov (United States)

    Rosnell, Tomi; Honkavaara, Eija

    2012-01-01

    The objective of this investigation was to develop and investigate methods for point cloud generation by image matching using aerial image data collected by quadrocopter type micro unmanned aerial vehicle (UAV) imaging systems. Automatic generation of high-quality, dense point clouds from digital images by image matching is a recent, cutting-edge step forward in digital photogrammetric technology. The major components of the system for point cloud generation are a UAV imaging system, an image data collection process using high image overlaps, and post-processing with image orientation and point cloud generation. Two post-processing approaches were developed: one of the methods is based on Bae Systems’ SOCET SET classical commercial photogrammetric software and another is built using Microsoft®’s Photosynth™ service available in the Internet. Empirical testing was carried out in two test areas. Photosynth processing showed that it is possible to orient the images and generate point clouds fully automatically without any a priori orientation information or interactive work. The photogrammetric processing line provided dense and accurate point clouds that followed the theoretical principles of photogrammetry, but also some artifacts were detected. The point clouds from the Photosynth processing were sparser and noisier, which is to a large extent due to the fact that the method is not optimized for dense point cloud generation. Careful photogrammetric processing with self-calibration is required to achieve the highest accuracy. Our results demonstrate the high performance potential of the approach and that with rigorous processing it is possible to reach results that are consistent with theory. We also point out several further research topics. Based on theoretical and empirical results, we give recommendations for properties of imaging sensor, data collection and processing of UAV image data to ensure accurate point cloud generation. PMID:22368479

  4. Point cloud generation from aerial image data acquired by a quadrocopter type micro unmanned aerial vehicle and a digital still camera.

    Science.gov (United States)

    Rosnell, Tomi; Honkavaara, Eija

    2012-01-01

    The objective of this investigation was to develop and investigate methods for point cloud generation by image matching using aerial image data collected by quadrocopter type micro unmanned aerial vehicle (UAV) imaging systems. Automatic generation of high-quality, dense point clouds from digital images by image matching is a recent, cutting-edge step forward in digital photogrammetric technology. The major components of the system for point cloud generation are a UAV imaging system, an image data collection process using high image overlaps, and post-processing with image orientation and point cloud generation. Two post-processing approaches were developed: one of the methods is based on Bae Systems' SOCET SET classical commercial photogrammetric software and another is built using Microsoft(®)'s Photosynth™ service available in the Internet. Empirical testing was carried out in two test areas. Photosynth processing showed that it is possible to orient the images and generate point clouds fully automatically without any a priori orientation information or interactive work. The photogrammetric processing line provided dense and accurate point clouds that followed the theoretical principles of photogrammetry, but also some artifacts were detected. The point clouds from the Photosynth processing were sparser and noisier, which is to a large extent due to the fact that the method is not optimized for dense point cloud generation. Careful photogrammetric processing with self-calibration is required to achieve the highest accuracy. Our results demonstrate the high performance potential of the approach and that with rigorous processing it is possible to reach results that are consistent with theory. We also point out several further research topics. Based on theoretical and empirical results, we give recommendations for properties of imaging sensor, data collection and processing of UAV image data to ensure accurate point cloud generation. PMID:22368479

  5. Digital systems to acquire radiological imaging. Characteristics and quality control; Sistemas digitales de adquisicion de imagenes radiograficas. Caracteristicas y Control de Calidad

    Energy Technology Data Exchange (ETDEWEB)

    Torres Cabrera, R.; Hernando Gonzalez, I.

    2006-07-01

    Due to its special characteristics, quality control in digital radiographic systems is very important, even more than in conventional film-screen systems. Differences between digital and analogical images,a in terms of dynamics range, spatial and contrast resolution, and the flexibility of data post-processing require some actions to maintain clinical images in an optimum quality level. Revision 1 of the Spanish Protocol of Quality Control in Diagnostic Radiology includes a chapter dedicated to the quality control of these digital systems for the acquisition of radiographic images. In this paper the different parameters for quality control procedures are described. Also some difficulties to be concerned about (absence of levels of tolerance, access to the raw-data images and related information, availability of use anthropomorphic phantoms, etc, etc) are noted, as well as the most significant aspects of the differences in relation to the ana logical systems. (Author) 15 refs.

  6. Laboratory-acquired brucellosis

    DEFF Research Database (Denmark)

    Fabiansen, C.; Knudsen, J.D.; Lebech, A.M.

    2008-01-01

    Brucellosis is a rare disease in Denmark. We describe one case of laboratory-acquired brucellosis from an index patient to a laboratory technician following exposure to an infected blood culture in a clinical microbiology laboratory Udgivelsesdato: 2008/6/9......Brucellosis is a rare disease in Denmark. We describe one case of laboratory-acquired brucellosis from an index patient to a laboratory technician following exposure to an infected blood culture in a clinical microbiology laboratory Udgivelsesdato: 2008/6/9...

  7. Research on the System Error Analysis and Compensation Method for the 3-D Profile Measurement with CCD Based on Linear Structure Lighting

    International Nuclear Information System (INIS)

    For the 3-D profile measurement with CCD, the calibration of CCD measurement system is still the focus of the researchers' attention. Firstly taking no account of some factors, such as the CCD lens aberration, image process error, etc., the principle error of the CCD calibration method constructing the coordinates mapping relation from image coordinates to space coordinates based on the polynomial fitting solution is analyzed through the experimental data in the paper. Then the paper analyzes the device error and operation error that is mainly from CCD lens aberration and image process. By measuring the standard geometry element, the error value can be picked up on the different depth position of field. After filtering the noise, the system error can be got, and can be used to compensate and amend the measurement result. The experimental result shows that with the system error compensation method, the measurable depth of field can be increased efficiently and the precision of the measurement result can be control within ±50um with common table of which the simple axis machine precision is 15um and open-loop control driven by the stepper motor, which can meet the profile measuring requirements well

  8. Contribution to the tracking and the 3D reconstruction of scenes composed of torus from image sequences a acquired by a moving camera

    International Nuclear Information System (INIS)

    The three-dimensional perception of the environment is often necessary for a robot to correctly perform its tasks. One solution, based on the dynamic vision, consists in analysing time-varying monocular images to estimate the spatial geometry of the scene. This thesis deals with the reconstruction of torus by dynamic vision. Though this object class is restrictive, it enables to tackle the problem of reconstruction of bent pipes usually encountered in industrial environments. The proposed method is based on the evolution of apparent contours of objects in the sequence. Using the expression of torus limb boundaries, it is possible to recursively estimate the object three-dimensional parameters by minimising the error between the predicted projected contours and the image contours. This process, which is performed by a Kalman filter, does not need a precise knowledge of the camera displacement or any matching of the tow limbs belonging to the same object. To complete this work, temporal tracking of objects which deals with occlusion situations is proposed. The approach consists in modeling and interpreting the apparent motion of objects in the successive images. The motion interpretation, based on a simplified representation of the scene, allows to recover pertinent three-dimensional information which is used to manage occlusion situations. Experiments, on synthetic and real images, proves he validity of the tracking and the reconstruction processes. (author)

  9. [Indication of neuro-imaging for the initial management and the follow-up of acute community-acquired bacterial meningitis].

    Science.gov (United States)

    Béquet, D; de Broucker, T

    2009-01-01

    Lumbar puncture is the best way to prove bacterial meningitis. It should be performed without any delay if the diagnosis is suspected. Herniation is a rare complication of LP. CT is normal in most cases of purulent meningitis, including those complicated by a subsequent herniation; normal CT results does not mean that performing a LP is safe. Three main clinical features can help determine which patient is at risk of herniation and should have a CT before LP. This risk has to be determined rapidly in the emergency ward while assessing anamnestic data, localization signs or symptoms, and level of consciousness. Cranial imaging (mainly MRI) is useful in the course of bacterial meningitis. Patients who do not respond well to treatment or with atypical presentation, persistence of fever, or new neurological signs should undergo brain imaging; MRI and CT may identify subdural effusions, brain abscesses, empyemas, hydrocephaly, or brain parenchymal changes (cerebritis, infarction, hemorrhage). CT and MRI are useful to screen for an ENT cause of bacterial meningitis, and mandatory in case of pneumococcal meningitis. Numerous MRI sequences are useful to identify bacterial meningitis complications: SE T1 without and with gadolinium injection, SE T2, FLAIR, gradient-echo T2, diffusion weighted imaging, MR angiography. PMID:19398288

  10. Pneumonia - adults (community acquired)

    Science.gov (United States)

    ... breathing (respiratory) condition in which there is an infection of the lung. This article covers community-acquired pneumonia (CAP). This type of pneumonia is found in persons who have not recently been in the hospital or another health care facility such as a ...

  11. Etiopathology of acquired cholesteatoma

    Directory of Open Access Journals (Sweden)

    Prabodh Karnik

    2011-01-01

    Full Text Available The etiopathology of acquired cholesteatoma has undergone numerous changes over the past 150 years. However, certain facts stand out with clarity. The presence of cytokeratins in acquired cholesteatoma, which are akin to those found in the tympanic membrane and external auditory canal, shows that these are probably the site of origin of acquired cholesteatoma. The cholesteatoma sac also shows its greatest growth at its tympanic membrane attachment into the middle ear. Implantations of squamous epithelium due to trauma or surgery could be another originating factor. The basic pathology is the formation of papillary cones from the tympanic membrane or external auditory canal, which progress from microcholesteatoma to frank cholesteatoma with keratin collections. There is an altered matrix metalloproteinase pathway. Tumor necrosis factor activation with altered wound healing process contributes to the collateral destruction of bone. Trisomy and aneuploidy of chromosome 8 predispose to cholesteatoma formation in affected individuals. In this article, we present the etiopathology of acquired cholesteatoma as it stands today.

  12. SU-E-J-10: A Moving-Blocker-Based Strategy for Simultaneous Megavoltage and Kilovoltage Scatter Correction in Cone-Beam Computed Tomography Image Acquired During Volumetric Modulated Arc Therapy

    Energy Technology Data Exchange (ETDEWEB)

    Ouyang, L; Lee, H; Wang, J [UT Southwestern Medical Center, Dallas, TX (United States)

    2014-06-01

    Purpose: To evaluate a moving-blocker-based approach in estimating and correcting megavoltage (MV) and kilovoltage (kV) scatter contamination in kV cone-beam computed tomography (CBCT) acquired during volumetric modulated arc therapy (VMAT). Methods: XML code was generated to enable concurrent CBCT acquisition and VMAT delivery in Varian TrueBeam developer mode. A physical attenuator (i.e., “blocker”) consisting of equal spaced lead strips (3.2mm strip width and 3.2mm gap in between) was mounted between the x-ray source and patient at a source to blocker distance of 232mm. The blocker was simulated to be moving back and forth along the gantry rotation axis during the CBCT acquisition. Both MV and kV scatter signal were estimated simultaneously from the blocked regions of the imaging panel, and interpolated into the un-blocked regions. Scatter corrected CBCT was then reconstructed from un-blocked projections after scatter subtraction using an iterative image reconstruction algorithm based on constraint optimization. Experimental studies were performed on a Catphan 600 phantom and an anthropomorphic pelvis phantom to demonstrate the feasibility of using moving blocker for MV-kV scatter correction. Results: MV scatter greatly degrades the CBCT image quality by increasing the CT number inaccuracy and decreasing the image contrast, in addition to the shading artifacts caused by kV scatter. The artifacts were substantially reduced in the moving blocker corrected CBCT images in both Catphan and pelvis phantoms. Quantitatively, CT number error in selected regions of interest reduced from 377 in the kV-MV contaminated CBCT image to 38 for the Catphan phantom. Conclusions: The moving-blockerbased strategy can successfully correct MV and kV scatter simultaneously in CBCT projection data acquired with concurrent VMAT delivery. This work was supported in part by a grant from the Cancer Prevention and Research Institute of Texas (RP130109) and a grant from the American

  13. Simplificando a obtenção e a utilização de imagens digitais: scanners e câmeras digitais How to easily acquire and use digital images: scanners and digital cameras

    Directory of Open Access Journals (Sweden)

    André Wilson Machado

    2004-08-01

    Orthodontics, associated with the introduction of "Digital Photography" allows the clinician to acquire things ever imagined, facilitating the orthodontic diagnosis, improving the doctor/doctor and doctor/patient communication, illustrating scientific communications in speeches, conferences and articles, being thereby, an excellent tool for teaching and research. In order to take advantages of this new field, the orthodontic records including photographs, models and radiographs must be converted into digital images. Therefore, as we enter into the "digital world", the aim of this paper is to clarify some basic concepts regarding the digital imaging and try to answer the must common questions about this topic: How to convert digitally the orthodontic records with a scanner? How to acquire digital images with a digital camera? At what resolution in DPI (dot per inch or in Megapixel (MP, file size and file format should the images have to fulfill my usual demands? At what resolution should the images have in order to be used in the computer monitor? And what resolution should the images be imported into presentation programs in order to be displayed in multimedia projectors? And at last, how to easily acquire digital images that will be used in scientific papers?

  14. Data Extraction from Computer Acquired Images of a Given 3D Environment for Enhanced Computer Vision and its Applications in Kinematic Design of Robos

    Directory of Open Access Journals (Sweden)

    K. Selvaraj

    2010-01-01

    Full Text Available Problem statement: Literature review was mainly aiming at recognition of objects by the computer and to make explicit the information that is implicit in the attributes of 3D objects and their relative positioning in the 3D Environment (3DE as seen in the 2D images. However quantitative estimate of position of objects in the 3DE in terms of their x, y and z co-ordinates was not touched upon. This issue assumes important dimension in areas like Kinematic Design of Robos (KDR, while the Robo is negotiating with z field or Depth Field (DF. Approach: The existing methods such as pattern matching used by Robos for Depth Visualization (DV using a set of external commands, were reviewed in detail. A methodology was developed in this study to enable the Robo to quantify the depth by itself, instead of looking for external commands. Results: The Results are presented and discussed. The Results are presented and discussed. The major conclusions drawn based on the results were listed. Conclusion: The major contribution of the present study consists of computing the Depth (D1 corresponding to the depth (d measured from the photographic image of a 3DE. It had been concluded that, there exists an excellent agreement between the computed depth D1 and the corresponding actual Depth (D. The percent deviation of D1 from D (DP lies between ±2 over the entire region of the (DF. Through suitable interfacing of the developed equation with the kinematic design of Robos, the Robo can generate its own commands for DF negotiations.

  15. Dynamics of cell and tissue growth acquired by means of 25 mm2 to 10 cm2 lens-free imaging

    Science.gov (United States)

    Momey, F.; Coutard, J.-G.; Bordy, T.; Navarro, F.; Menneteau, M.; Dinten, J.-M.; Allier, C.

    2015-03-01

    In this paper, we discuss a new methodology based on lens-free imaging to perform wound healing assay with unprecedented statistics. Our video lens-free microscopy setup is a simple optical system featuring only a CMOS sensor and a semi coherent illumination system. Yet it is a powerful means for the real-time monitoring of cultivated cells. It presents several key advantages, e.g., integration into standard incubator, compatibility with standard cell culture protocol, simplicity and ease of use. It can perform the follow-up in a large field of view (25 mm2) of several crucial parameters during the culture of cells i.e. their motility, their proliferation rate or their death. Consequently the setup can gather large statistics both in space and time. But in the case of tissue growth experiments, the field of view of 25 mm2 remains not sufficient and results can be biased depending on the position of the device with respect to the recipient of the cell culture. Hence, to conduct exhaustive wound healing assay, here we propose to enlarge the field of view up to 10 cm2 through two different approaches. The first method consists in performing a scan of the cell culture by moving the source/sensor couple and then stitch the stack of images. The second is to make an acquisition by scanning with a line scan camera. The two approaches are compared in term of resolution, complexity and acquisition time. Next we have performed acquisitions of wound healing assay (keratinocytes HaCaT) both in real-time (25 mm2) and in final point (10 cm2) to assess the combination of these two complementary modalities. In the future, we aim at combining directly super wide field of view acquisitions (>10 cm2) with real time ability inside the incubator.

  16. Acquired epidermolysis bullosa

    OpenAIRE

    Maricel Sucar Batista; Yanier Serrano García; Taimí Miranda Vergara

    2015-01-01

    Epidermolysis bullosa is a group of diseases or skin disorders genetically transmitted and it is characterized by the appearance of bullae, ulcers and skin wounds. It usually appears at birth or in the first months of life. This is a case of a 72-year-old female patient who comes to the dermatology department with skin lesions of 6 months of evolution. A skin biopsy was performed, taking a sample for direct and indirect immunofluorescence. Acquired epidermolysis bullosa of unknown etiology wa...

  17. Acquired hypertrichosis lanuginosa

    Directory of Open Access Journals (Sweden)

    Kumar Pramod

    1993-01-01

    Full Text Available Acquired hypertirichosis lanuginose developed rapidly in a patient with no detectable malignancy. Soft, fine, downy hair growth was noticed on the face, ears, limbs and trunk. Bilaterally symmetrical vitiliginous macules were present on the ear and preauricular region. This case is reported because of its rarity, absence of any detectable malignancy and development of vitiligo, which to our knowledge has not been reported earlier.

  18. AIDS: acquired immunodeficiency syndrome

    OpenAIRE

    Gilmore, N. J.; Beaulieu, R.; Steben, M.; Laverdière, M.

    2002-01-01

    Acquired immunodeficiency syndrome, or AIDS, is a new illness that occurs in previously healthy individuals. It is characterized by immunodeficiency, opportunistic infections and unusual malignant diseases. Life-threatening single or multiple infections with viruses, mycobacteria, fungi or protozoa are common. A rare neoplasm, Kaposi's sarcoma, has developed in approximately one third of patients with AIDS. More than 800 cases of AIDS have been reported in North America, over 24 of them in Ca...

  19. Summary of results and conclusions based on analysis of volume imaging and high spectral resolution lidar data acquired during FIRE phase 1, part 1

    Science.gov (United States)

    Grund, Christian J.; Eloranta, E. W.

    1990-01-01

    The collection of long term global statistics on cloud cover may be most easily accomplished with satellite based observations; however, measurements derived from passive satellite retrieval methods must be calibrated and verified by in situ or ground based remote sensor observations. Verification is not straight forward, however, because the highly variable nature of cloud altitude, morphology, and optical characteristics complicates the scaling of point measurements to satellite footprint sized areas. This is particularly evident for cirrus clouds which may be organized on horizontal scales of 10's of meters to 8 km or more, and have optical depths ranging from less than .003 to greater than 3. Cirrus clouds can strongly influence earths' radiative balance, but, because they are often transmissive, cirrus clouds are difficult to detect and characterize from satellite measurements. Because of its precise ranging capabilities, spatial resolution and sensitivity, lidar observations have played an important role in the detection, depiction, and characterization of cirrus clouds. Some of the characteristics of cirrus clouds are summarized which observed the High Spectral Resolution and Volume Imaging Lidars during the phase 1 IFO and ETO periods.

  20. Spatial Co-Registration of Ultra-High Resolution Visible, Multispectral and Thermal Images Acquired with a Micro-UAV over Antarctic Moss Beds

    Directory of Open Access Journals (Sweden)

    Darren Turner

    2014-05-01

    Full Text Available In recent times, the use of Unmanned Aerial Vehicles (UAVs as tools for environmental remote sensing has become more commonplace. Compared to traditional airborne remote sensing, UAVs can provide finer spatial resolution data (up to 1 cm/pixel and higher temporal resolution data. For the purposes of vegetation monitoring, the use of multiple sensors such as near infrared and thermal infrared cameras are of benefit. Collecting data with multiple sensors, however, requires an accurate spatial co-registration of the various UAV image datasets. In this study, we used an Oktokopter UAV to investigate the physiological state of Antarctic moss ecosystems using three sensors: (i a visible camera (1 cm/pixel, (ii a 6 band multispectral camera (3 cm/pixel, and (iii a thermal infrared camera (10 cm/pixel. Imagery from each sensor was geo-referenced and mosaicked with a combination of commercially available software and our own algorithms based on the Scale Invariant Feature Transform (SIFT. The validation of the mosaic’s spatial co-registration revealed a mean root mean squared error (RMSE of 1.78 pixels. A thematic map of moss health, derived from the multispectral mosaic using a Modified Triangular Vegetation Index (MTVI2, and an indicative map of moss surface temperature were then combined to demonstrate sufficient accuracy of our co-registration methodology for UAV-based monitoring of Antarctic moss beds.

  1. Combined Spectral and Spatial Modeling of Corn Yield Based on Aerial Images and Crop Surface Models Acquired with an Unmanned Aircraft System

    Directory of Open Access Journals (Sweden)

    Jakob Geipel

    2014-10-01

    Full Text Available Precision Farming (PF management strategies are commonly based on estimations of within-field yield potential, often derived from remotely-sensed products, e.g., Vegetation Index (VI maps. These well-established means, however, lack important information, like crop height. Combinations of VI-maps and detailed 3D Crop Surface Models (CSMs enable advanced methods for crop yield prediction. This work utilizes an Unmanned Aircraft System (UAS to capture standard RGB imagery datasets for corn grain yield prediction at three early- to mid-season growth stages. The imagery is processed into simple VI-orthoimages for crop/non-crop classification and 3D CSMs for crop height determination at different spatial resolutions. Three linear regression models are tested on their prediction ability using site-specific (i unclassified mean heights, (ii crop-classified mean heights and (iii a combination of crop-classified mean heights with according crop coverages. The models show determination coefficients \\({R}^{2}\\ of up to 0.74, whereas model (iii performs best with imagery captured at the end of stem elongation and intermediate spatial resolution (0.04m\\(\\cdot\\px\\(^{-1}\\.Following these results, combined spectral and spatial modeling, based on aerial images and CSMs, proves to be a suitable method for mid-season corn yield prediction.

  2. Learning-By-Being-Acquired

    DEFF Research Database (Denmark)

    Colombo, Massimo G.; Moreira, Solon; Rabbiosi, Larissa

    -categorization theories, we argue that R&D team reorganization increases the acquired inventors’ use of the prior stock of technological knowledge of the acquiring firm after the acquisition. Furthermore, this effect is enhanced if acquired inventors have higher innovation ability relative to their acquiring peers but is...

  3. Acquired von Willebrand Syndrome

    Institute of Scientific and Technical Information of China (English)

    郭涛

    2005-01-01

    @@ Acquired von Willebrand syndrome (AvWS) is kind of bleeding disorder with laboratory findings similar to those in congenital yon Willebrand disease (vWD).AvWS doesn's have any personal or family history of bleeding, but is associated with certain diseases or abnormal conditions or drugs. Although AvWS is being stated as a rare disease, it has gained more and more attention during the past years. Not because of the severity of the disease, but it is more common than we thought and most patients don' t have a proper diagnosis.

  4. Acquired epidermolysis bullosa

    Directory of Open Access Journals (Sweden)

    Maricel Sucar Batista

    2015-12-01

    Full Text Available Epidermolysis bullosa is a group of diseases or skin disorders genetically transmitted and it is characterized by the appearance of bullae, ulcers and skin wounds. It usually appears at birth or in the first months of life. This is a case of a 72-year-old female patient who comes to the dermatology department with skin lesions of 6 months of evolution. A skin biopsy was performed, taking a sample for direct and indirect immunofluorescence. Acquired epidermolysis bullosa of unknown etiology was diagnosed. Treatment was started with low-dose colchicine to increase it later, according to the patient’s tolerance and disease progression.

  5. The role of high-resolution computed tomography (HRCT) and magnetic resonance imaging (MRI) in the diagnosis of preoperative and postoperative complications caused by acquired cholesteatomas; CT und MRT des erworbenen Cholesteatoms: Prae- und postoperative Bildgebung

    Energy Technology Data Exchange (ETDEWEB)

    Krestan, C.; Czerny, C. [Abteilung fuer Osteologie, Univ.-Klinik fuer Radiodiagnostik, Wien (Austria); Gstoettner, W. [Univ.-Klinik fuer Hals-Nasen-Ohren-Heilkunde, Frankfurt (Germany); Franz, P. [Univ.-Klinik fuer Hals-Nasen-Ohren-Heilkunde, Wien (Austria)

    2003-03-01

    The role of high-resolution computed tomography (HRCT) and magnetic resonance imaging (MRI) in the diagnosis of preoperative and postoperative complications caused by acquired cholesteatomas will be described in this paper. The pre- and postoperative imaging of the temporal bone was performed with HRCT and MRI. HRCT and MRI were performed in the axial and coronal plane. MRI was done with T2 weighted and T1 weighted sequences both before and after the intravenous application of contrast material. All imaging findings were confirmed clinically or surgically. The preoperative cholesteatoma-caused complications depicted by HRCT included bony erosions of the ossicles, scutum, facial canal in the middle ear, tympanic walls including the tegmen tympani, and of the labyrinth. The preoperative cholesteatoma-caused complications depicted by MRI included signs indicative for labyrinthitis, and brain abscess. Postoperative HRCT depicted bony erosions caused by recurrent cholesteatoma, bony defects of the facial nerve and of the labyrinth, and a defect of the tegmen tympani with a soft tissue mass in the middle ear. Postoperative MRI delineated neuritis of the facial nerve, labyrinthitis, and a meningo-encephalocele protruding into the middle ear. HRCT and MRI are excellent imaging tools to depict either bony or soft tissue complications or both if caused by acquired cholesteatomas. According to our findings and to the literature HRCT and MRI are complementary imaging methods to depict pre- or postoperative complications of acquired cholesteatomas if these are suspected by clinical examination. (orig.) [German] In dieser Arbeit wird die Rolle der hochaufloesenden Computertomographie (HRCT) und der Magnetresonanztomographie (MRT) zur Abklaerung prae- und postoperativ bedingter Komplikationen erworbener Cholesteatome beschrieben. Die Bildgebung wurde sowohl mit der HRCT als auch mit der MRT durchgefuehrt. Die HRCT und die MRT wurden in axialer und koronaler Ebene (auch

  6. Acquired Blaschkoid dermatitis

    Directory of Open Access Journals (Sweden)

    Mercy P

    2007-01-01

    Full Text Available Acquired Blaschkoid dermatitis characterised by unilateral relapsing inflammatory disease along the lines of Blaschko. A 40-year-old Indian male presented with unilateral erythematous, itchy grouped papules on the left side of the chest, abdomen, back and left arm of 15 days duration. The eruption stopped abruptly at the midline of the torso, completely sparing the right side of the body. The lesions were arranged in whorls and streaks corresponding to the lines of Blaschko. Skin biopsy showed hyperkeratosis and features suggestive of sub-acute spongiotic dermatitis with lymphocytic infiltrate around the blood vessels in the dermis. Patient was diagnosed as a case of Blaschkoid dermatitis. To the best of our knowledge, this is the first case of this condition being reported from India.

  7. A novel Region of Interest (ROI) imaging technique for biplane imaging in interventional suites: high-resolution small field-of-view imaging in the frontal plane and dose-reduced, large field-of-view standard-resolution imaging in the lateral plane

    Science.gov (United States)

    Swetadri Vasan, Setlur Nagesh; Ionita, C.; Bednarek, D. R.; Rudin, Stephen

    2014-03-01

    Endovascular-Image-Guided-Interventional (EIGI) treatment of neuro-vascular conditions such as aneurysms, stenosed arteries, and vessel thrombosis make use of treatment devices such as stents, coils, and balloons which have very small feature sizes, 10's of microns to a few 100's of microns, and hence demand a high resolution imaging system. The current state-of-the-art flat panel detector (FPD) has about a 200-um pixel size with the Nyquist of 2.5 lp/mm. For higher-resolution imaging a charge-coupled device (CCD) based Micro-Angio - Fluoroscope (MAF-CCD) with a pixel size of 35um (Nyquist of 11 lp/mm) was developed and previously reported. Although the detector addresses the high resolution needs, the Field-Of-View (FOV) is limited to 3.5 cm x 3.5 cm, which is much smaller than current FPDs. During the use of the MAF-CCD for delicate parts of the intervention, it may be desirable to have real-time monitoring outside the MAF FOV with a low dose, and lower, but acceptable, quality image. To address this need, a novel imaging technique for biplane imaging systems has been developed, using an MAFCCD in the frontal plane and a dose-reduced standard large FOV imager in the lateral plane. The dose reduction is achieved by using a combination of ROI fluoroscopy and spatially different temporal filtering, a technique that has been previously presented. In order to evaluate this technique, a simulation using images acquired during an actual EIGI treatment on a patient, followed by an actual implementation on phantoms is presented.

  8. Psychological issues in acquired facial trauma

    Directory of Open Access Journals (Sweden)

    De Sousa Avinash

    2010-01-01

    Full Text Available The face is a vital component of one′s personality and body image. There are a vast number of variables that influence recovery and rehabilitation from acquired facial trauma many of which are psychological in nature. The present paper presents the various psychological issues one comes across in facial trauma patients. These may range from body image issues to post-traumatic stress disorder symptoms accompanied by anxiety and depression. Issues related to facial and body image affecting social life and general quality of life are vital and the plastic surgeon should be aware of such issues and competent to deal with them in patients and families.

  9. Intercontrole acquiring by Framatome

    International Nuclear Information System (INIS)

    The Framatome group, as the worldwide leader in nuclear power plant construction, has reinforced his competences in nuclear services thanks to the acquiring of the Intercontrole company, specialized in non-destructive testing in nuclear and industrial environments. After a presentation of the functioning principle and of the safety aspects of a PWR reactor, this press dossier presents in a first part the role of nuclear services and in particular of non-destructive testing in nuclear power plants (in-service inspection, regulatory aspects, testing processes). This part is illustrated with some examples of inspection performed on some components of the primary coolant loop (steam generators, reactor vessel, pressurizer, pipes, primary pumps). A second part presents the technical centres and units of Framatome in charge of performing non-destructive inspections, while a third part describes the industrial policy and strategy of the group in this domain (market of nuclear park maintenance in France, in the USA and worldwide, creation of the 'inspection and control' centre of Framatome). A last part presents the activities of the Intercontrole company and of its daughter companies with some examples of actions realized in the nuclear and natural gas domains. (J.S.)

  10. Earth Knowledge Acquired by Middle School Students

    Science.gov (United States)

    Ride, Sally

    2008-01-01

    Earth Knowledge Acquired by Middle School Students (EarthKAM), an education activity, allows middle school students to program a digital camera on board the International Space Station to photograph a variety of geographical targets for study in the classroom. Photos are made available on the web for viewing and study by participating schools around the world. Educators use the images for projects involving Earth Science, geography, physics, and social science.

  11. Acquired CNS lesions in fetal MRI

    International Nuclear Information System (INIS)

    Acquired central nervous system (CNS) lesions are often subtle; therefore, the prenatal diagnosis of these lesions is extremely important. The fetal ultrasound examination and magnetic resonance imaging (MRI) are two important imaging methods that give an insight into these types lesions. The method of choice during pregnancy is still fetal ultrasound; however, fetal MRI is important when there are certain pathologies, e.g. periventricular leukomalacia (PVL) or malformations of the vein of Galen. In this manner clinicians can plan further therapy after childbirth in advance (e.g. cerebral angiography or embolization). (orig.)

  12. Analysis of the Imaging Speed of the CCD Based Neutron Digital Radiography System%基于CCD的中子数字照相系统成像速度分析

    Institute of Scientific and Technical Information of China (English)

    唐彬; 李西安; 霍合勇; 薛斌

    2007-01-01

    成像速度是中子冷阴极放电器(CCD)数字照相系统的主要性能参数.根据中子数字照相的原理、光学成像的基本关系式和CCD的特性,提出了一种基于CCD的中子数字照相系统的成像速度理论推算方法,对SPRR-300中子数字照相系统成像速度进行了计算,并与试验结果相比较证明,理论计算与试验基本吻合,计算方法可信.

  13. And the Winner is - Acquired

    DEFF Research Database (Denmark)

    Henkel, Joachim; Rønde, Thomas; Wagner, Marcus

    2015-01-01

    New entrants to a market tend to be superior to incumbents in originating radical innovations. We provide a new explanation for this phenomenon, based on markets for technology. It applies in industries where successful entrepreneurial firms, or their technologies, are acquired by incumbents that...... lower probability accompanies higher value in case of success—that is, a more radical innovation. In the second stage, successful entrants bid to be acquired by the incumbent. We assume that entrants cannot survive on their own, so being acquired amounts to a prize in a contest. We identify an...

  14. Pathology of the thoracic wall: congenital and acquired

    Energy Technology Data Exchange (ETDEWEB)

    Garcia-Pena, Pilar; Barber, Ignasi [Hospital Materno-Infantil, Pediatric Radiology, Barcelona (Spain)

    2010-06-15

    This review aims to cover the main congenital and acquired lesions that arise in the thoracic wall of infants and children. Imaging often plays an essential role in the evaluation of symptomatic and asymptomatic thoracic wall abnormalities. The use of appropriate imaging modalities for each condition will be addressed, as well as the range of benign and malignant conditions that can occur. (orig.)

  15. Sigmoid plate dehiscence: Congenital or acquired condition?

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Zhaohui, E-mail: lzhtrhos@163.com [Capital Medical University, Beijing Tongren Hospital, No 1 Dong Jiao Min Street, Dongcheng District, Beijing 100730 (China); Li, Jing, E-mail: lijingxbh@yahoo.com.cn [Capital Medical University, Beijing Tongren Hospital, No 1 Dong Jiao Min Street, Dongcheng District, Beijing 100730 (China); Zhao, Pengfei, E-mail: zhaopengf05@163.com [Capital Medical University, Beijing Friendship Hospital, No 95 Yongan Road, Xicheng District, Beijing 100050 (China); Lv, Han, E-mail: chrislvhan@126.com [Capital Medical University, Beijing Friendship Hospital, No 95 Yongan Road, Xicheng District, Beijing 100050 (China); Dong, Cheng, E-mail: derc007@sina.com [Capital Medical University, Beijing Friendship Hospital, No 95 Yongan Road, Xicheng District, Beijing 100050 (China); Liu, Wenjuan, E-mail: wenjuanliu@163.com [Jining No. 1 People' s Hospital, No. 6 Health Street, Jining 272100 (China); Wang, Zhenchang, E-mail: cjr.wzhch@vip.163.com [Capital Medical University, Beijing Friendship Hospital, No 95 Yongan Road, Xicheng District, Beijing 100050 (China)

    2015-05-15

    Highlights: • CT with multiplanar reformations can accurately display the sigmoid platet dehiscence. • The prevalence of sigmoid plate dehiscence was no significant difference among different age groups. • The size of sigmoid plate bony defects were not statistically different among different age groups. • The sigmoid plate dehiscence is more commonly a congenital than an acquired condition. - Abstract: Background and purpose: The imaging features of sigmoid plate dehiscence-induced pulsatile tinnitus have been presented. The origin of the sigmoid plate dehiscence, however, remains unclear. Our aim was to assess the prevalence and extent of sigmoid plate dehiscence on computed tomography (CT) images in multiple age groups to determine whether this condition is more likely to be congenital or acquired. Materials and methods: We retrospectively reviewed contrast-enhanced CT images of sigmoid plates of temporal bones in 504 patients. Each temporal bone was characterized as normal or dehiscent. Patients were then subcategorized into four age groups, and the prevalence and extent of dehiscent sigmoid plates in each group were calculated and compared. Results: Overall, 80 patients had sigmoid plate dehiscence, nine of whom had it bilaterally. In successively older age groups, the prevalences of sigmoid plate dehiscence were 18.9%, 20.1%, 14.5%, and 12.7%, respectively. Respective average anteroposterior bony defect diameters were 3.7 ± 1.7, 3.0 ± 1.3, 3.1 ± 1.5, and 3.0 ± 1.1 mm. Respective average vertical bony defect diameters were 3.6 ± 2.3, 2.6 ± 1.2, 3.2 ± 1.5, and 3.0 ± 1.7 mm. The prevalence and extent of sigmoid plate dehiscence were not statistically different among the four age groups. Conclusions: The similar radiologic prevalence and extent of dehiscent sigmoid plates among the age groups suggest that the dehiscence is more commonly a congenital than an acquired condition.

  16. Sigmoid plate dehiscence: Congenital or acquired condition?

    International Nuclear Information System (INIS)

    Highlights: • CT with multiplanar reformations can accurately display the sigmoid platet dehiscence. • The prevalence of sigmoid plate dehiscence was no significant difference among different age groups. • The size of sigmoid plate bony defects were not statistically different among different age groups. • The sigmoid plate dehiscence is more commonly a congenital than an acquired condition. - Abstract: Background and purpose: The imaging features of sigmoid plate dehiscence-induced pulsatile tinnitus have been presented. The origin of the sigmoid plate dehiscence, however, remains unclear. Our aim was to assess the prevalence and extent of sigmoid plate dehiscence on computed tomography (CT) images in multiple age groups to determine whether this condition is more likely to be congenital or acquired. Materials and methods: We retrospectively reviewed contrast-enhanced CT images of sigmoid plates of temporal bones in 504 patients. Each temporal bone was characterized as normal or dehiscent. Patients were then subcategorized into four age groups, and the prevalence and extent of dehiscent sigmoid plates in each group were calculated and compared. Results: Overall, 80 patients had sigmoid plate dehiscence, nine of whom had it bilaterally. In successively older age groups, the prevalences of sigmoid plate dehiscence were 18.9%, 20.1%, 14.5%, and 12.7%, respectively. Respective average anteroposterior bony defect diameters were 3.7 ± 1.7, 3.0 ± 1.3, 3.1 ± 1.5, and 3.0 ± 1.1 mm. Respective average vertical bony defect diameters were 3.6 ± 2.3, 2.6 ± 1.2, 3.2 ± 1.5, and 3.0 ± 1.7 mm. The prevalence and extent of sigmoid plate dehiscence were not statistically different among the four age groups. Conclusions: The similar radiologic prevalence and extent of dehiscent sigmoid plates among the age groups suggest that the dehiscence is more commonly a congenital than an acquired condition

  17. Cerebral involvement in acquired immunodeficiency syndrome (AIDS)

    International Nuclear Information System (INIS)

    Involvement of the central nervous system in acquired immune deficiency syndrome (AIDS) is usually due to opportunistic infections; these frequently offer a difficult differential diagnostic problem. Imaging methods play an important part in the elucidation of symptoms. CT and MR findings were analysed in 13 patients with AIDS and neurological symptoms. Some infections of the central nervous system (encephalitis of unknown aetiology, cytomegalic encephalitis, meningitis) may show cerebral atrophy or even no morphological changes. Toxoplasmosis and PML are the most common opportunistic infections typical changes on CT and MR may lead to diagnosis. MR offers advantages compared with CT in its higher sensitivity for the demonstration even of small lesions. (orig.)

  18. MRI of fetal acquired brain lesions

    International Nuclear Information System (INIS)

    Acquired fetal brain damage is suspected in cases of destruction of previously normally formed tissue, the primary cause of which is hypoxia. Fetal brain damage may occur as a consequence of acute or chronic maternal diseases, with acute diseases causing impairment of oxygen delivery to the fetal brain, and chronic diseases interfering with normal, placental development. Infections, metabolic diseases, feto-fetal transfusion syndrome, toxic agents, mechanical traumatic events, iatrogenic accidents, and space-occupying lesions may also qualify as pathologic conditions that initiate intrauterine brain damage. MR manifestations of acute fetal brain injury (such as hemorrhage or acute ischemic lesions) can easily be recognized, as they are hardly different from postnatal lesions. The availability of diffusion-weighted sequences enhances the sensitivity in recognizing acute ischemic lesions. Recent hemorrhages are usually readily depicted on T2 (*) sequences, where they display hypointense signals. Chronic fetal brain injury may be characterized by nonspecific changes that must be attributable to the presence of an acquired cerebral pathology. The workup in suspected acquired fetal brain injury also includes the assessment of extra-CNS organs that may be affected by an underlying pathology. Finally, the placenta, as the organ that mediates oxygen delivery from the maternal circulation to the fetus, must be examined on MR images

  19. MRI of fetal acquired brain lesions

    Energy Technology Data Exchange (ETDEWEB)

    Prayer, Daniela [Department of Radiodiagnostics, Medical University of Vienna (Austria)]. E-mail: daniela.prayer@meduniwien.ac.at; Brugger, Peter C. [Center of Anatomy and Cell Biology, Medical University of Vienna (Austria); Kasprian, Gregor [Department of Radiodiagnostics, Medical University of Vienna (Austria); Witzani, Linde [Department of Radiodiagnostics, Medical University of Vienna (Austria); Helmer, Hanns [Department of Obstetrics and Gynecology, Medical University of Vienna (Austria); Dietrich, Wolfgang [Department of Neurosurgery, Medical University of Vienna (Austria); Eppel, Wolfgang [Department of Obstetrics and Gynecology, Medical University of Vienna (Austria); Langer, Martin [Department of Obstetrics and Gynecology, Medical University of Vienna (Austria)

    2006-02-15

    Acquired fetal brain damage is suspected in cases of destruction of previously normally formed tissue, the primary cause of which is hypoxia. Fetal brain damage may occur as a consequence of acute or chronic maternal diseases, with acute diseases causing impairment of oxygen delivery to the fetal brain, and chronic diseases interfering with normal, placental development. Infections, metabolic diseases, feto-fetal transfusion syndrome, toxic agents, mechanical traumatic events, iatrogenic accidents, and space-occupying lesions may also qualify as pathologic conditions that initiate intrauterine brain damage. MR manifestations of acute fetal brain injury (such as hemorrhage or acute ischemic lesions) can easily be recognized, as they are hardly different from postnatal lesions. The availability of diffusion-weighted sequences enhances the sensitivity in recognizing acute ischemic lesions. Recent hemorrhages are usually readily depicted on T2 (*) sequences, where they display hypointense signals. Chronic fetal brain injury may be characterized by nonspecific changes that must be attributable to the presence of an acquired cerebral pathology. The workup in suspected acquired fetal brain injury also includes the assessment of extra-CNS organs that may be affected by an underlying pathology. Finally, the placenta, as the organ that mediates oxygen delivery from the maternal circulation to the fetus, must be examined on MR images.

  20. Acquiring taste in home economics?

    DEFF Research Database (Denmark)

    Stenbak Larsen, Christian

    2015-01-01

    that the pupils were encouraged to use their senses: listen to things frying, touch the meat to check if it was done and taste the food in the process of seasoning it. But while some children learned what the teachers expected: to produce well tasting food, others learned to cook very salty and hot food...... appreciated by the group of boys, and others again learned to stick with their idiosyncrasies when pressured by the teacher. Conclusions: Children were acquiring taste in the home economic lessons, but not only the kind of tastes that the teacher had planned for. This leads to reflections on the very complex...... process of taste acquiring and to a call for further research into taste acquiring in complex real life contexts as home economics lessons....

  1. Acquired Aplastic Anemia in Children

    OpenAIRE

    Hartung, Helge D.; Olson, Timothy S.; Bessler, Monica

    2013-01-01

    This article provides a practice-based and concise review of the etiology, diagnosis, and management of acquired aplastic anemia in children. Bone marrow transplantation, immunosuppressive therapy, and supportive care are discussed in detail. The aim is to provide the clinician with a better understanding of the disease and to offer guidelines for the management of children with this uncommon yet serious disorder.

  2. Acquired anhidrosis a case report

    Directory of Open Access Journals (Sweden)

    Nair Laxmi

    1992-01-01

    Full Text Available A 30-year -old man was seen for acquired anhidrosis. There was no systemic disease. Vasomotor functions were normal. Biopsy showed normal sweat glands and ducts. Intravenous injection of neostigmine could produce profuse sweating on the face, trunk and arms. The disorder is likely to be due to a peripheral dysautonomia selectively affecting the sudomotor function.

  3. Acquired anhidrosis a case report

    OpenAIRE

    Nair Laxmi; Beena D; Manohar S

    1992-01-01

    A 30-year -old man was seen for acquired anhidrosis. There was no systemic disease. Vasomotor functions were normal. Biopsy showed normal sweat glands and ducts. Intravenous injection of neostigmine could produce profuse sweating on the face, trunk and arms. The disorder is likely to be due to a peripheral dysautonomia selectively affecting the sudomotor function.

  4. Occupationally Acquired American Cutaneous Leishmaniasis

    Directory of Open Access Journals (Sweden)

    Maria Edileuza Felinto de Brito

    2012-01-01

    Full Text Available We report two occupationally acquired cases of American cutaneous leishmaniasis (ACL: one accidental laboratory autoinoculation by contaminated needlestick while handling an ACL lesion sample, and one acquired during field studies on bird biology. Polymerase chain reaction (PCR assays of patient lesions were positive for Leishmania, subgenus Viannia. One isolate was obtained by culture (from patient 2 biopsy samples and characterized as Leishmania (Viannia naiffi through an indirect immunofluorescence assay (IFA with species-specific monoclonal antibodies (mAbs and by multilocus enzyme electrophoresis (MLEE. Patients were successfully treated with N-methyl-glucamine. These two cases highlight the potential risks of laboratory and field work and the need to comply with strict biosafety procedures in daily routines. The swab collection method, coupled with PCR detection, has greatly improved ACL laboratory diagnosis.

  5. CNOOC Acquires Oversea Assets Successfully

    Institute of Scientific and Technical Information of China (English)

    Hu Senlin

    2006-01-01

    @@ After last year CNOOC's bidding for buy the US energy company Unocal Corp lost out to the Chevron Corporation, it conducted the crossing-border asset-acquirement again in the beginning of this year. On Jan. 9, 2006,CNOOC Ltd signed a definitive agreement with Nigeria South Atlantic Petroleum Limited (SAPETRO) to acquire a 45 % working interest in an offshore oil developing license OML 130 in Nigeria for US$2.268 billion cash. The purchase will be funded by the internal capital resources of CNOOC Ltd. In which, US$1.75 billion will pay for buying SAPETRO, and the remaining cash will be used to pay for the early operation cost.

  6. Cogema acquires TOTAL's uranium assets

    International Nuclear Information System (INIS)

    On April 28, France's nuclear fuel cycle conglomerate Cogema and petroleum group TOTAL announced a plan in which Cogema will assume ownership of TOTAL's uranium assets worldwide, and as part of the deal, each firm will acquire shares of the other. On June 2, the agreement will be submitted to shareholders and, assuming it is approved, will go into effect this year. The agreement calls for TOTAL to acquire a 10.8-percent share in Cogema, thus becoming its first private sector shareholder, by underwriting a reserve capital increase of FF1.5 billion (approximately US$283 million). In return, Cogema will pay FF2.52 billion for approximately 4.3 percent of TOTAL, as part of a reserve capital increase totalling FF4.07 billion

  7. Images

    Data.gov (United States)

    National Aeronautics and Space Administration — Images for the website main pages and all configurations. The upload and access points for the other images are: Website Template RSW images BSCW Images HIRENASD...

  8. Acquired causes of intestinal malabsorption.

    Science.gov (United States)

    van der Heide, F

    2016-04-01

    This review focuses on the acquired causes, diagnosis, and treatment of intestinal malabsorption. Intestinal absorption is a complex process that depends on many variables, including the digestion of nutrients within the intestinal lumen, the absorptive surface of the small intestine, the membrane transport systems, and the epithelial absorptive enzymes. Acquired causes of malabsorption are classified by focussing on the three phases of digestion and absorption: 1) luminal/digestive phase, 2) mucosal/absorptive phase, and 3) transport phase. Most acquired diseases affect the luminal/digestive phase. These include short bowel syndrome, extensive small bowel inflammation, motility disorders, and deficiencies of digestive enzymes or bile salts. Diagnosis depends on symptoms, physical examination, and blood and stool tests. There is no gold standard for the diagnosis of malabsorption. Further testing should be based on the specific clinical context and the suspected underlying disease. Therapy is directed at nutritional support by enteral or parenteral feeding and screening for and supplementation of deficiencies in vitamins and minerals. Early enteral feeding is important for intestinal adaptation in short bowel syndrome. Medicinal treatment options for diarrhoea in malabsorption include loperamide, codeine, cholestyramine, or antibiotics. PMID:27086886

  9. Inhibitors against the coagulation factors spontaneously acquired: Acquired B Hemophilia

    OpenAIRE

    Claudia Lucía Sossa Melo; Sara Inés Jiménez Sanguino; Pilar Rodríguez

    2003-01-01

    Spontaneously acquired inhibitors to factor IX, are extremely rare. A 70-year-old male, presented with major continuous post-orthopedic surgery bleeding. His initial APTT was 77.4 s (normal range, 25-36) and normal PT. Expanded APTT corrects, results in favor of deficit of factor IX, confirming the level of dose of IX factor: 52% (NR 70–125%) with normal factor VIII. It was realized with fresh frozen plasma, and by the fifth day of treatment, he presents a bruise in the surgery bed with radic...

  10. Knowledge transfer - Acquiring implicit knowledge

    International Nuclear Information System (INIS)

    Many organisations have recognised the problem of experts taking home a huge amount of specific knowledge, which they have gathered in their department, when they leave. The successor is capable only of acquiring explicit expertise because implicit experiences are not documented and therefore no more available. That is why we have started this pilot study in order to try to conserve the above mentioned tacit and implicit knowledge and to make it available to other colleagues. Using a semi-standardised interview we elicit tacit knowledge from the expert and summarise it in a report. This interview-guideline forms the basis of in-depth investigation for implicit knowledge. (author)

  11. Acquiring 4D Thoracic CT Scans Using Ciné CT Acquisition

    Science.gov (United States)

    Low, Daniel

    One method for acquiring 4D thoracic CT scans is to use ciné acquisition. Ciné acquisition is conducted by rotating the gantry and acquiring x-ray projections while keeping the couch stationary. After a complete rotation, a single set of CT slices, the number corresponding to the number of CT detector rows, is produced. The rotation period is typically sub second so each image set corresponds to a single point in time. The ciné image acquisition is repeated for at least one breathing cycle to acquire images throughout the breathing cycle. Once the images are acquired at a single couch position, the couch is moved to the abutting position and the acquisition is repeated. Post-processing of the images sets typically resorts the sets into breathing phases, stacking images from a specific phase to produce a thoracic CT scan at that phase. Benefits of the ciné acquisition protocol include, the ability to precisely identify the phase with respect to the acquired image, the ability to resort images after reconstruction, and the ability to acquire images over arbitrarily long times and for arbitrarily many images (within dose constraints).

  12. Pseudomona pseudomallei community acquired pneumonia

    International Nuclear Information System (INIS)

    This is the first published case report en Colombia about pseudomona pseudomallei community acquired pneumonia. This uncommon pathogen is from the epidemiological standpoint a very important one and medical community should be aware to look after it in those patients where no other etiological pathogen is recovered. A brief summary about epidemiology is showed, emphasizing those regions where it can be found. Likewise, comments about the differential diagnosis are important since it should be considered in those patients where tuberculosis is suspected. This is particularly representative for countries with high tuberculosis rates. Furthermore, a microbiological review is shown, emphasizing on isolation techniques, descriptions about therapeutics and other regarding treatment issues according international standards. Finally; a description about the clinical picture, laboratory findings, treatment and evolution of the case reported are shown for discussion

  13. Complement's participation in acquired immunity

    DEFF Research Database (Denmark)

    Nielsen, Claus Henrik; Leslie, Robert Graham Quinton

    2002-01-01

    B cell receptor for antigen (BCR), a complex composed of the iC3b/C3d fragment-binding complement type 2 receptor (CR2, CD21) and its signaling element CD19 and the IgG-binding receptor FcgammaRIIb (CD32). The positive or negative outcome of signaling through this triad is determined by the context...... in which antigen is seen, be it alone or in association with natural or induced antibodies and/or C3-complement fragments. The aim of this review is to describe the present status of our understanding of complement's participation in acquired immunity and the regulation of autoimmune responses.......The preliminary evidence for the involvement of complement in promoting primary humoral responses dates back over a quarter of a century. However, it is only in the course of the past decade or so that the detailed mechanisms underlying complement's influence have been characterized in depth. It is...

  14. Acquired pathology of the pediatric spine and spinal cord

    International Nuclear Information System (INIS)

    Pediatric spine pathology poses a diagnostic challenge for radiologists. Acquired spine pathology often yields nonspecific signs and symptoms in children, especially in the younger age groups, and diagnostic delay can carry significant morbidity. This review is focused on some of the more common diagnostic dilemmas we face when attempting to evaluate and diagnose acquired pediatric spine anomalies in daily practice. An understanding of some of the key differentiating features of these disease processes in conjunction with pertinent history, physical exam, and advanced imaging techniques can indicate the correct diagnosis. (orig.)

  15. Acquired pathology of the pediatric spine and spinal cord

    Energy Technology Data Exchange (ETDEWEB)

    Palasis, Susan; Hayes, Laura L. [Children' s Healthcare of Atlanta, Department of Radiology at Scottish Rite, Atlanta, GA (United States)

    2015-09-15

    Pediatric spine pathology poses a diagnostic challenge for radiologists. Acquired spine pathology often yields nonspecific signs and symptoms in children, especially in the younger age groups, and diagnostic delay can carry significant morbidity. This review is focused on some of the more common diagnostic dilemmas we face when attempting to evaluate and diagnose acquired pediatric spine anomalies in daily practice. An understanding of some of the key differentiating features of these disease processes in conjunction with pertinent history, physical exam, and advanced imaging techniques can indicate the correct diagnosis. (orig.)

  16. Acquired vulval lymphangiectases mimicking genital warts

    OpenAIRE

    Sharma Rajeev; Tomar Sudarshan; Chandra Mithilesh

    2002-01-01

    Acquired lymphangiectasia can sometimes occur on the vulva and cause diagnostic difficulties especially if they have a warty appearance. We report a case of acquired vulva I lymphangiectasia which mimicked genital warts.

  17. Acquired vulval lymphangiectases mimicking genital warts

    Directory of Open Access Journals (Sweden)

    Sharma Rajeev

    2002-01-01

    Full Text Available Acquired lymphangiectasia can sometimes occur on the vulva and cause diagnostic difficulties especially if they have a warty appearance. We report a case of acquired vulva I lymphangiectasia which mimicked genital warts.

  18. Infections Acquired in the Garden.

    Science.gov (United States)

    Cunha, Cheston B; Cunha, Burke A

    2015-10-01

    Gardening is a wonderful pastime, and the garden is a very peaceful place to enjoy one's vacation. However, the garden may be a treacherous place for very young or compromised hosts when one takes into account the infectious potential residing in the soil, as well as the insect vectors on plants and animals. Even normal hosts may acquire a variety of infections from the soil, animals, or animal-related insect bites. The location of the garden, its natural animal and insect inhabitants, and the characteristics of the soil play a part in determining its infectious potential. The most important factor making the garden an infectious and dangerous place is the number and interaction of animals, whether they are pets or wild, that temporarily use the garden for part of their daily activities. The clinician should always ask about garden exposure, which will help in eliminating the diagnostic possibilities for the patient. The diagnostic approach is to use epidemiological principles in concert with clinical clues, which together should suggest a reasonable list of diagnostic possibilities. Organ involvement and specific laboratory tests help further narrow the differential diagnosis and determine the specific tests necessary to make a definitive diagnosis. PMID:26542044

  19. Surface Sampler Arm Acquiring Sample

    Science.gov (United States)

    1976-01-01

    Operation of the surface sampler in obtaining Martian soil for Viking 2's molecular analysis experiment last Saturday (September 25) was closely monitored by one of the Lander cameras because of the precision required in trenching the small area--8 by 9 inches-surrounded by rocks. Dubbed 'Bonneville Salt Flats,' the exposure of thin crust appeared unique in contrast with surrounding materials and became a prime target for organic analysis in spite of potential hazards. Large rock in foreground is 8 inches high. At left, the sampler scoop has touched the surface, missing the rock at upper left by a comfortable 6 inches, and the backhoe has penetrated the surface about one-half inch. The scoop was then pulled back to sample the desired point and (second photo) the backhoe furrowed the surface pulling a piece of thin crust toward the spacecraft. The initial touchdown and retraction sequence was used to avoid a collision between a rock in the shadow of the arm and a plate joining the arm and scoop. The rock was cleared by 2 to 3 inches. The third picture was taken 8 minutes after the scoop touched the surface and shows that the collector head has acquired a quantity of soil. With surface sampler withdrawn (right), the foot-long trench is seen between the rocks. The trench is three inches wide and about 1 1/2 to 2 inches deep. The scoop reached to within 3 inches of the rock at far end of trench. Penetration appears to have left a cavernous opening roofed by the crust and only about one inch of undisturbed crust separates the deformed surface and the rock.

  20. 17 CFR 210.8-06 - Real estate operations acquired or to be acquired.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Real estate operations acquired or to be acquired. 210.8-06 Section 210.8-06 Commodity and Securities Exchanges SECURITIES AND... Statements of Smaller Reporting Companies § 210.8-06 Real estate operations acquired or to be acquired....

  1. Colour Image Represention of Multispectral Image Fusion

    OpenAIRE

    Preema Mole; Mathurakani, M

    2016-01-01

    The availability of imaging sensors operating in multiple spectral bands has led to the requirement of image fusion algorithms that would combine the image from these sensors in an efficient way to give an image that is more perceptible to human eye. Multispectral Image fusion is the process of combining images optically acquired in more than one spectral band. In this paper, we present a pixel-level image fusion that combines four images from four different spectral bands namely ...

  2. Epidural anesthesia as a cause of acquired spinal subarachnoid cysts

    International Nuclear Information System (INIS)

    Six patients with acquired spinal subarachnoid cysts secondary to epidural anesthesia were evaluated with MR imaging (seven patients) and intraoperative US (three patients). The cysts were located in the lower cervical and thoracic spine. Adhesions and irregularity of the cord surface were frequently noted. Associated intramedullary lesions, including intramedullary cysts and myelomalacia, were seen in two of the patients. Arachnoiditis was unsuspected clinically in three patients, and MR imaging proved to be the diagnostic examination that first suggested the cause of the patients symptoms. The underlying mechanism for the formation of these cysts is a chemically induced arachnoiditis

  3. Space acquired imagery, a versatile tool in the development of energy sources

    Science.gov (United States)

    Amsbury, D. L.

    1975-01-01

    The two-dimensional images acquired by satellite-borne instruments are continuous, they supplement surface data, subsurface data, and other geophysical data, and they can cut the amount of field work required for a given task by a whole order of magnitude. Images acquired with instruments mounted on the Apollo and Skylab orbiting spacecraft, and on the RB-57 and U-2 aircraft, are displayed and discussed.

  4. Optical imaging of alpha emitters: simulations, phantom, and in vivo results

    Science.gov (United States)

    Boschi, Federico; Meo, Sergio Lo; Rossi, Pier Luca; Calandrino, Riccardo; Sbarbati, Andrea; Spinelli, Antonello E.

    2011-12-01

    There has been growing interest in investigating both the in vitro and in vivo detection of optical photons from a plethora of beta emitters using optical techniques. In this paper we have investigated an alpha particle induced fluorescence signal by using a commercial CCD-based small animal optical imaging system. The light emission of a 241Am source was simulated using GEANT4 and tested in different experimental conditions including the imaging of in vivo tissue. We believe that the results presented in this work can be useful to describe a possible mechanism for the in vivo detection of alpha emitters used for therapeutic purposes.

  5. Acquired Zinc Deficiency in an Adult Female

    OpenAIRE

    Mohanan Saritha; Divya Gupta; Laxmisha Chandrashekar; Devinder M Thappa; Nachiappa G Rajesh

    2012-01-01

    Acrodermatitis enteropathica is an autosomal recessive inherited disorder of zinc absorption. Acquired cases are reported occasionally in patients with eating disorders or Crohn′s disease. We report a 24-year-old housewife with acquired isolated severe zinc deficiency with no other comorbidities to highlight the rare occurrence of isolated nutritional zinc deficiency in an otherwise normal patient.

  6. And the Winner is – Acquired

    DEFF Research Database (Denmark)

    Henkel, Joachim; Rønde, Thomas; Wagner, Marcus

    value in case of success—that is, a more radical innovation. In the second stage, successful entrants bid to be acquired by the incumbent. We assume that entrants cannot survive on their own, so being acquired amounts to a ‘prize’ in a contest. We identify an equilibrium in which the incumbent chooses...

  7. Acquired intrathoracic kidney in thoracic kyphosis

    International Nuclear Information System (INIS)

    Two cases of acquired intrathoracic kidney associated with thoracic kyphosis are reported, with emphasis on the radiographic manifestations. A search of the scientific literature disclosed that the acquired type of this abnormality is rare. The importance of recognizing this entity from a differential diagnostic standpoint is underscored. (author)

  8. Seeing the eyes in acquired prosopagnosia.

    Science.gov (United States)

    Pancaroglu, Raika; Hills, Charlotte S; Sekunova, Alla; Viswanathan, Jayalakshmi; Duchaine, Brad; Barton, Jason J S

    2016-08-01

    Case reports have suggested that perception of the eye region may be impaired more than that of other facial regions in acquired prosopagnosia. However, it is unclear how frequently this occurs, whether such impairments are specific to a certain anatomic subtype of prosopagnosia, and whether these impairments are related to changes in the scanning of faces. We studied a large cohort of 11 subjects with this rare disorder, who had a variety of occipitotemporal or anterior temporal lesions, both unilateral and bilateral. Lesions were characterized by functional and structural imaging. Subjects performed a perceptual discrimination test in which they had to discriminate changes in feature position, shape, or external contour. Test conditions were manipulated to stress focused or divided attention across the whole face. In a second experiment we recorded eye movements while subjects performed a face memory task. We found that greater impairment for eye processing was more typical of subjects with occipitotemporal lesions than those with anterior temporal lesions. This eye selectivity was evident for both eye position and shape, with no evidence of an upper/lower difference for external contour. A greater impairment for eye processing was more apparent under attentionally more demanding conditions. Despite these perceptual deficits, most subjects showed a normal tendency to scan the eyes more than the mouth. We conclude that occipitotemporal lesions are associated with a partially selective processing loss for eye information and that this deficit may be linked to loss of the right fusiform face area, which has been shown to have activity patterns that emphasize the eye region. PMID:27288649

  9. Congenital and acquired orthopedic abnormalities in patients with myelomeningocele.

    Science.gov (United States)

    Westcott, M A; Dynes, M C; Remer, E M; Donaldson, J S; Dias, L S

    1992-11-01

    This article presents a radiologic review of the spectrum of acquired and congenital orthopedic abnormalities found in patients with myelomeningocele. These abnormalities are caused predominantly by muscle imbalance, paralysis, and decreased sensation in the lower extremity. Iatrogenic injury, such as a postoperative tethered cord, may also cause bone abnormalities. Selected images were obtained from more than 800 children. Important entities presented include spinal curvatures such as kyphosis, scoliosis, and lordosis; subluxation and dislocation of the hip, coxa valga, contractures of the hip, and femoral torsion; knee deformities; rotational abnormalities of the lower extremity and external and internal torsion; ankle and foot abnormalities such as ankle valgus, calcaneus foot, congenital vertical talus (rocker-bottom deformity), and talipes equinovarus; and metaphyseal, diaphyseal, and physeal fractures. Familiarity with congenital abnormalities and an understanding of the pathogenesis of acquired disorders in patients with myelomeningocele are essential for proper radiologic interpretation and timely therapy. PMID:1439018

  10. Enhancing Medicares Hospital Acquired Conditions Policy

    Data.gov (United States)

    U.S. Department of Health & Human Services — The current Medicare policy of non-payment to hospitals for Hospital Acquired Conditions (HAC) seeks to avoid payment for preventable complications identified...

  11. Hospital-Acquired Condition Reduction Program

    Data.gov (United States)

    U.S. Department of Health & Human Services — In October 2014, CMS began reducing Medicare payments for subsection (d) hospitals that rank in the worst performing quartile with respect to hospital-acquired...

  12. Acquired Inventors’ Productivity after Horizontal Acquisition

    DEFF Research Database (Denmark)

    Colombo, Massimo G.; Moreira, Solon; Rabbiosi, Larissa

    Effective integration of the R&D functions of the acquired and acquiring firms is essential for knowledge recombination after acquisition. However, prior research suggests that the post-acquisition integration process often damages the inventive labor force. We argue that an examination of the mu......Effective integration of the R&D functions of the acquired and acquiring firms is essential for knowledge recombination after acquisition. However, prior research suggests that the post-acquisition integration process often damages the inventive labor force. We argue that an examination...... of the multifaceted nature of the integration process further enhances our understanding of which conditions will be more or less detrimental for corporate inventors. We focus on R&D teams which are the immediate organizational context in which inventors operate and drawing on insights from learning theory...

  13. Mariner 10 Image Archive

    Data.gov (United States)

    National Aeronautics and Space Administration — The Mariner 10 Image Archive includes tools to view shaded relief maps of the surface of Mercury, a 3D globe, and all images acquired by NASA's Mariner 10 mission.

  14. Infections acquired in clinical laboratories in Utah.

    OpenAIRE

    Jacobson, J.T.; Orlob, R B; Clayton, J L

    1985-01-01

    We reviewed laboratory-acquired infections occurring in Utah from 1978 through 1982. Written and telephone interviews of supervisors of 1,191 laboratorians revealed an estimated annual incidence of 3 laboratory-acquired infections per 1,000 employees. Infections, in order of frequency, included hepatitis B (clinical cases), shigellosis, pharyngitis, cellulitis, tuberculosis (skin test conversion), conjunctivitis, and non-A, non-B hepatitis. One-half of large laboratories (over 25 employees), ...

  15. The Acquired Immunodeficiency Syndrome: current status.

    OpenAIRE

    Quagliarello, V.

    1982-01-01

    A recently recognized syndrome of acquired immunodeficiency (Acquired Immunodeficiency Syndrome-AIDS) has arisen since June 1981. It has received international attention. The clinical spectrum consists of repeated opportunistic infections, rare malignancies, and autoimmune phenomena, occurring in previously healthy adults with no history of an immunologic disorder. The population subset at risk for this syndrome appears to be predominantly homosexual American males and intravenous drug abuser...

  16. ATF beam image monitor software

    International Nuclear Information System (INIS)

    We report about software for the beam image analysis at ATF. We developed image analysis software with a Linux computer. It acquire image data from a video and an IEEE1394 digital camera of the analog. (author)

  17. Surgical correction of acquired unilateral diaphragmatic paralysis by plication technique

    Directory of Open Access Journals (Sweden)

    Christos F. Kampolis

    2013-06-01

    Full Text Available Summary: Acquired diaphragmatic paralysis may compromise lung mechanics and cause dyspnoea and/or lead to respiratory failure in the long term. A 76 year-old female patient presented with progressive worsening of dyspnoea and spirometric indices, and imaging studies revealed elevation of the left hemidiaphragm. Surgical correction was carried out by diaphragmatic plication technique, through a mini-thoracotomy approach. Immediate alleviation (within days of her symptoms was observed, while improvement of radiological and pulmonary function tests occurred some weeks later. Pneumon 2013,26(2

  18. Do Acquirer Capabilities Affect Acquisition Performance? Examining Strategic and Effectiveness Capabilities in Acquirers

    OpenAIRE

    Mudde, Paul A.; Brush, Thomas

    2006-01-01

    This paper examines acquisition performance from the perspective of acquirer capabilities. It argues that the strategic capabilities underpinning a firm’s competitive strategy can be utilized to create economic value in acquisitions. Acquirers with strong cost leadership capabilities are expected to leverage these capabilities to reduce post-acquisition costs as they integrate acquisition targets. Acquirers with strong differentiation capabilities are expected to utilize their strategic capab...

  19. Small UAV-Acquired, High-resolution, Georeferenced Still Imagery

    Energy Technology Data Exchange (ETDEWEB)

    Ryan Hruska

    2005-09-01

    Currently, small Unmanned Aerial Vehicles (UAVs) are primarily used for capturing and down-linking real-time video. To date, their role as a low-cost airborne platform for capturing high-resolution, georeferenced still imagery has not been fully utilized. On-going work within the Unmanned Vehicle Systems Program at the Idaho National Laboratory (INL) is attempting to exploit this small UAV-acquired, still imagery potential. Initially, a UAV-based still imagery work flow model was developed that includes initial UAV mission planning, sensor selection, UAV/sensor integration, and imagery collection, processing, and analysis. Components to support each stage of the work flow are also being developed. Critical to use of acquired still imagery is the ability to detect changes between images of the same area over time. To enhance the analysts’ change detection ability, a UAV-specific, GIS-based change detection system called SADI or System for Analyzing Differences in Imagery is under development. This paper will discuss the associated challenges and approaches to collecting still imagery with small UAVs. Additionally, specific components of the developed work flow system will be described and graphically illustrated using varied examples of small UAV-acquired still imagery.

  20. Acquired angioedema secondary to hormone replacement therapy

    Directory of Open Access Journals (Sweden)

    Malani Kumar

    2005-10-01

    Full Text Available Angioedema is a potentially life threatening condition and may be either inherited or acquired. The latter is rare with only a handful of cases reported in the world literature. Presenting complaints are often vague. Those most commonly described include swelling in the subcutaneous and submucosal tissues. Patients presenting with laryngeal edema have high mortality, and high clinical suspicion is necessary to avoid instrumentation, which can precipitate laryngeal spasm. We present a review of reported cases of hormonally induced hereditary angioedema, along with a report of a patient with acquired angioedema secondary to hormone replacement therapy. To the best of our knowledge, this case probably represents the first reported case of acquired angioedema secondary to hormone replacement therapy.

  1. Photoreflectance imaging of a quasi one-dimensional ``thermal wave''

    Science.gov (United States)

    Tessier, G.; Jumel, J.; Rochais, D.; Enguehard, F.; Fournier, D.

    2005-06-01

    We propose a simple configuration to obtain images of the diffusion of a quasi 1-dimensional “thermal wave” in homogeneous or heterogeneous media. One side of the sample is broadly heated by a modulated CO2 laser beam, while the alternative temperature distribution is imaged on a perpendicular facet using a CCD-based thermoreflectance microscope. We validate the principle of this technique on a simple aluminium-coated glass substrate, in which amplitude and phase images of the reflectivity variations are measured. From these measurements, we derive a diffusivity of 10-2 cm-2s-1, which is close to that of glass. This measurement geometry should prove useful for the characterization of complex media in which micro scale heat diffusion is difficult to measure and model.

  2. The application of image quality measurements for digital angiography

    International Nuclear Information System (INIS)

    The image quality (IQ) evaluation of a charge-coupled device (CCD)-based digital angiography system was assessed with respect to modulation transfer function and noise power spectrum. These values were used to calculate the system's frequency-dependent detective quantum efficiency (DQE). The X-ray image detector was an image intensifier (II) lens coupled to a CCD camera. Two measurement setups were used. Setup A is standard IQ assessment, while Setup B more closely represented clinical conditions (polymethyl methacrylate (PMMA) of varying thickness placed between the X-ray tube and II, with test object positioned between PMMA slices 30 cm from the II). Exposure parameters varied according to automatic brightness control settings. Setup B included X-ray radiation scattered by the patient-PMMA. A clinical DQE, describing the transmission of the input signal-to-noise ratio associated with both primary and secondary X-ray spectra, was defined. (authors)

  3. Differential Protein Expression in Congenital and Acquired Cholesteatomas.

    Directory of Open Access Journals (Sweden)

    Seung-Ho Shin

    Full Text Available Congenital cholesteatomas are epithelial lesions that present as an epithelial pearl behind an intact eardrum. Congenital and acquired cholesteatomas progress quite differently from each other and progress patterns can provide clues about the unique origin and pathogenesis of the abnormality. However, the exact pathogenic mechanisms by which cholesteatomas develop remain unknown. In this study, key proteins that directly affect cholesteatoma pathogenesis are investigated with proteomics and immunohistochemistry. Congenital cholesteatoma matrices and retroauricular skin were harvested during surgery in 4 patients diagnosed with a congenital cholesteatoma. Tissue was also harvested from the retraction pocket in an additional 2 patients during middle ear surgery. We performed 2-dimensional (2D electrophoresis to detect and analyze spots that are expressed only in congenital cholesteatoma and matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF/MS to separate proteins by molecular weight. Protein expression was confirmed by immunohistochemical staining. The image analysis of 2D electrophoresis showed that 4 congenital cholesteatoma samples had very similar protein expression patterns and that 127 spots were exclusively expressed in congenital cholesteatomas. Of these 127 spots, 10 major spots revealed the presence of titin, forkhead transcription activator homolog (FKH 5-3, plectin 1, keratin 10, and leucine zipper protein 5 by MALDI-TOF/MS analysis. Immunohistochemical staining showed that FKH 5-3 and titin were expressed in congenital cholesteatoma matrices, but not in acquired cholesteatomas. Our study shows that protein expression patterns are completely different in congenital cholesteatomas, acquired cholesteatomas, and skin. Moreover, non-epithelial proteins, including FKH 5-3 and titin, were unexpectedly expressed in congenital cholesteatoma tissue. Our data indicates that congenital cholesteatoma origins

  4. Synthetic Aperture Ultrasound Imaging

    DEFF Research Database (Denmark)

    Jensen, Jørgen Arendt; Nikolov, Svetoslav; Gammelmark, Kim Løkke;

    2006-01-01

    The paper describes the use of synthetic aperture (SA) imaging in medical ultrasound. SA imaging is a radical break with today's commercial systems, where the image is acquired sequentially one image line at a time. This puts a strict limit on the frame rate and the possibility of acquiring a...... SA imaging. Due to the complete data set, it is possible to have both dynamic transmit and receive focusing to improve contrast and resolution. It is also possible to improve penetration depth by employing codes during ultrasound transmission. Data sets for vector flow imaging can be acquired using...... short imaging sequences, whereby both the correct velocity magnitude and angle can be estimated. A number of examples of both phantom and in-vivo SA images will be presented measured by the experimental ultrasound scanner RASMUS to demonstrate the many benefits of SA imaging....

  5. Group Treatment in Acquired Brain Injury Rehabilitation

    Science.gov (United States)

    Bertisch, Hilary; Rath, Joseph F.; Langenbahn, Donna M.; Sherr, Rose Lynn; Diller, Leonard

    2011-01-01

    The current article describes critical issues in adapting traditional group-treatment methods for working with individuals with reduced cognitive capacity secondary to acquired brain injury. Using the classification system based on functional ability developed at the NYU Rusk Institute of Rehabilitation Medicine (RIRM), we delineate the cognitive…

  6. Immunomodulation in community-acquired pneumonia

    NARCIS (Netherlands)

    Remmelts, H.H.F.

    2013-01-01

    Community-acquired pneumonia (CAP) is a common disease with considerable morbidity and mortality, despite effective antibiotic treatment. In this thesis, we showed that the major causative microorganisms in CAP trigger distinct inflammatory response profiles in the host. While an inflammatory respon

  7. Sexually acquired Salmonella Typhi urinary tract infection.

    Science.gov (United States)

    Wielding, Sally; Scott, Gordon

    2016-05-01

    We report a case of isolated urinarySalmonella entericaserotype Typhi in an HIV-positive man who has sex with men. He was clinically well and blood and stool cultures were negative, indicating that this may have been a sexually acquired urinary tract infection. PMID:25953964

  8. Acquired secondary Grynfeltt's hernia: a case report

    International Nuclear Information System (INIS)

    Lumbar hernia is a rare condition whose diagnosis is hardly achieved. The prevalence is higher in elderly men. The present case report describes the case of a male, 78-year-old patient who underwent pleural effusion drainage 17 years before presenting with clinical manifestations and tomographic findings compatible with acquired secondary Grynfeltt's hernia. (author)

  9. Prevention of hospital-acquired hyponatraemia

    DEFF Research Database (Denmark)

    Lunøe, Mathilde; Overgaard-Steensen, C

    2015-01-01

    prevention of hospital-acquired hyponatraemia is an understanding of what determines plasma sodium concentration (P-[Na(+) ]) in the individual patient. P-[Na(+) ] is determined by balances of water and cations according to Edelman. This paper discusses the mechanisms influencing water and cation balances...

  10. Support Network Responses to Acquired Brain Injury

    Science.gov (United States)

    Chleboun, Steffany; Hux, Karen

    2011-01-01

    Acquired brain injury (ABI) affects social relationships; however, the ways social and support networks change and evolve as a result of brain injury is not well understood. This study explored ways in which survivors of ABI and members of their support networks perceive relationship changes as recovery extends into the long-term stage. Two…

  11. Interviewing Children with Acquired Brain Injury (ABI)

    Science.gov (United States)

    Boylan, Anne-Marie; Linden, Mark; Alderdice, Fiona

    2009-01-01

    Research into the lives of children with acquired brain injury (ABI) often neglects to incorporate children as participants, preferring to obtain the opinions of the adult carer (e.g. McKinlay et al., 2002). There has been a concerted attempt to move away from this position by those working in children's research with current etiquette…

  12. Monitoring Agitated Behavior After acquired Brain Injury

    DEFF Research Database (Denmark)

    Aadal, Lena; Mortensen, Jesper; Nielsen, Jørgen Feldbaek

    2015-01-01

    Purpose: To describe the onset, duration, intensity, and nursing shift variation of agitated behavior in patients with acquired brain injury (ABI) at a rehabilitation hospital. Design: Prospective descriptive study. Methods: A total of 11 patients with agitated behavior were included. Agitated...

  13. Avaliação da qualidade das imagens digitais adquiridas com diferentes resoluções em um sistema de armazenamento de fósforo Evaluation of the quality of digital images acquired with different resolutions in a storage phosphor system

    Directory of Open Access Journals (Sweden)

    Solange Maria de ALMEIDA

    2000-09-01

    Full Text Available O objetivo do presente trabalho foi avaliar comparativamente a qualidade das imagens adquiridas, por meio da placa de fósforo, com três diferentes resoluções - 150, 300 e 600 dpi, e a eficiência de alguns recursos de manipulação disponíveis no software do sistema estudado. Os objetos de análise constituíram-se de quinze dentes com a lima 8 em seu interior, cujas mensurações endodônticas foram realizadas por cinco avaliadores. O sistema digital utilizado foi o DenOptix (Dentsply International/Gendex Dental X-Ray Division, Des Plaines, IL. Os resultados mostraram diferença estatística entre as diferentes resoluções empregadas, com as imagens adquiridas com 150 dpi apresentando-se de qualidade inferior às de 300 e 600 dpi, estas equivalentes. Os diferentes recursos digitais empregados não se apresentaram estatisticamente significantes entre si. Com base nos resultados, conclui-se que as imagens de 150 dpi apresentam-se com qualidade inferior àquelas adquiridas com 300 e 600 dpi, que oferecem similar nível de eficiência, imagens em condições satisfatórias para uma análise radiográfica. Quanto a aplicação dos diferentes recursos de manipulação estudados, pode-se concluir, em função dos resultados equivalentes que apresentaram, que, em mensurações endodônticas, a escolha de se trabalhar com um recurso isoladamente ou em associação fica ao encargo de um critério subjetivo de seleção.The aim of this paper was to evaluate the quality of the image acquired with the DenOptix storage phosphor plate (Dentsply International/Gendex Dental X-Ray Division, Des Plaines, IL, with three different resolutions - 150, 300 and 600 dpi, as well as the efficiency of some tools that are available in such a kind of software. The objects analyzed were 15 teeth containing a #8 endodontic file in their root canal. Endodontic measurements were performed by 5 examiners. The results showed a statistically significant difference between

  14. Contribution to the tracking and the 3D reconstruction of scenes composed of torus from image sequences a acquired by a moving camera; Contribution au suivi et a la reconstruction de scenes constituees d`objet toriques a partir de sequences d`images acquises par une camera mobile

    Energy Technology Data Exchange (ETDEWEB)

    Naudet, S

    1997-01-31

    The three-dimensional perception of the environment is often necessary for a robot to correctly perform its tasks. One solution, based on the dynamic vision, consists in analysing time-varying monocular images to estimate the spatial geometry of the scene. This thesis deals with the reconstruction of torus by dynamic vision. Though this object class is restrictive, it enables to tackle the problem of reconstruction of bent pipes usually encountered in industrial environments. The proposed method is based on the evolution of apparent contours of objects in the sequence. Using the expression of torus limb boundaries, it is possible to recursively estimate the object three-dimensional parameters by minimising the error between the predicted projected contours and the image contours. This process, which is performed by a Kalman filter, does not need a precise knowledge of the camera displacement or any matching of the tow limbs belonging to the same object. To complete this work, temporal tracking of objects which deals with occlusion situations is proposed. The approach consists in modeling and interpreting the apparent motion of objects in the successive images. The motion interpretation, based on a simplified representation of the scene, allows to recover pertinent three-dimensional information which is used to manage occlusion situations. Experiments, on synthetic and real images, proves he validity of the tracking and the reconstruction processes. (author) 127 refs.

  15. Enhancement of the low resolution image quality using randomly sampled data for multi-slice MR imaging

    OpenAIRE

    Pang, Yong; Yu, Baiying; Zhang, Xiaoliang

    2014-01-01

    Low resolution images are often acquired in in vivo MR applications involving in large field-of-view (FOV) and high speed imaging, such as, whole-body MRI screening and functional MRI applications. In this work, we investigate a multi-slice imaging strategy for acquiring low resolution images by using compressed sensing (CS) MRI to enhance the image quality without increasing the acquisition time. In this strategy, low resolution images of all the slices are acquired using multiple-slice imag...

  16. Processed pseudogenes acquired somatically during cancer development

    OpenAIRE

    Cooke, Susanna L.; Shlien, Adam; Marshall, John; Pipinikas, Christodoulos P; Martincorena, Inigo; Tubio, Jose M. C.; Li, Yilong; Menzies, Andrew; Mudie, Laura; Ramakrishna, Manasa; Yates, Lucy; Davies, Helen; Bolli, Niccolo; Bignell, Graham R; Tarpey, Patrick S.

    2014-01-01

    Cancer evolves by mutation, with somatic reactivation of retrotransposons being one such mutational process. Germline retrotransposition can cause processed pseudogenes, but whether this occurs somatically has not been evaluated. Here we screen sequencing data from 660 cancer samples for somatically acquired pseudogenes. We find 42 events in 17 samples, especially non-small cell lung cancer (5/27) and colorectal cancer (2/11). Genomic features mirror those of germline LINE element retrotransp...

  17. Brucella abortus Infection Acquired in Microbiology Laboratories

    OpenAIRE

    Fiori, Pier Luigi; Mastrandrea, Scilla; Rappelli, Paola; Cappuccinelli, Piero

    2000-01-01

    We report an outbreak of laboratory-acquired Brucella abortus infection originating in the accidental breakage of a centrifuge tube. A total of 12 laboratory workers were infected (attack rate of 31%), with an incubation time ranging from 6 weeks to 5 months. Antibody titers were evaluated weekly in all personnel exposed, allowing the diagnosis of the infection in most cases before the onset of clinical symptoms, so that specific therapy could be administrated.

  18. Acquired resistance to immunotherapy and future challenges.

    Science.gov (United States)

    Restifo, Nicholas P; Smyth, Mark J; Snyder, Alexandra

    2016-02-01

    Advances in immunotherapy have resulted in remarkable clinical responses in some patients. However, one of the biggest challenges in cancer therapeutics is the development of resistant disease and disease progression on or after therapy. Given that many patients have now received various types of immunotherapy, we asked three scientists to give their views on the current evidence for whether acquired resistance to immunotherapy exists in patients and the future challenges posed by immunotherapy. PMID:26822578

  19. Molecular biological aspects of acquired bullous diseases

    DEFF Research Database (Denmark)

    Dabelsteen, Erik

    1998-01-01

    genes have been cloned. The antigens which react with autoantibodies from patients with bullous pemphigoid, cicatricial pemphigoid, acquired epidermolysis bullosa, and linear IgA disease are all proteins of the hemidesmosome basement membrane complex. Interestingly, most of the antigens also appear to...... be the target for mutations seen in patients with the inherited type of epidermolysis bullosa in which bullous lesions are a prominent clinical feature....

  20. Economics and Preventing Hospital-acquired Infection

    OpenAIRE

    Graves, Nicholas

    2004-01-01

    The economics of preventing hospital-acquired infections is most often described in general terms. The underlying concepts and mechanisms are rarely made explicit but should be understood for research and policy-making. We define the key economic concepts and specify an illustrative model that uses hypothetical data to identify how two related questions might be addressed: 1) how much should be invested for infection control, and 2) what are the most appropriate infection-control programs? We...

  1. Immunological memory and acquired immunodeficiency syndrome pathogenesis.

    OpenAIRE

    Kaur, A; Rosenzweig, M; Johnson, R. P.

    2000-01-01

    Infection with the human immunodeficiency virus results in profound perturbations in immunological memory, ultimately resulting in increased susceptibility to opportunistic infections and acquired immunodeficiency syndrome (AIDS). We have used rhesus macaques infected with the simian immunodeficiency virus (SIV) as a model to understand better the effects of AIDS virus infection on immunological memory. Acute infection with SIV resulted in significant deficits in CD4+ helper responses to cyto...

  2. A CMA position. Acquired immunodeficiency syndrome.

    OpenAIRE

    1989-01-01

    The following general principles serve as guidelines for various bodies, health care professionals and the general public. Specific aspects of infection with human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS) that relate to physicians' ethical responsibilities as well as society's moral obligations are discussed. Such matters include the need for education, research and treatment resources; the patient's right to investigation and treatment and to refusal of eith...

  3. Clinicopathological correlation of acquired hyperpigmentary disorders

    OpenAIRE

    Anisha B Patel; Raj Kubba; Asha Kubba

    2013-01-01

    Acquired pigmentary disorders are group of heterogenous entities that share single, most significant, clinical feature, that is, dyspigmentation. Asians and Indians, in particular, are mostly affected. Although the classic morphologies and common treatment options of these conditions have been reviewed in the global dermatology literature, the value of histpathological evaluation has not been thoroughly explored. The importance of accurate diagnosis is emphasized here as the underlying diseas...

  4. Acquired Factor VIII Inhibitors: Three Cases

    Directory of Open Access Journals (Sweden)

    Tay Za Kyaw

    2013-03-01

    Full Text Available Acquired hemophilia A is a rare, but devastating bleeding disorder caused by spontaneous development of autoantibodies directed against coagulation factor VIII. In 40%-50% of patients it is associated with such conditions as the postpartum period, malignancy, use of medications, and autoimmune diseases; however, its cause is unknown in most cases. Acquired hemophilia A should be suspected in patients that present with a coagulation abnormality, and a negative personal and family history of bleeding. Herein we report 3 patients with acquired hemophilia A that had different underlying pathologies, clinical presentations, and therapeutic responses. Factor VIII inhibitor formation in case 1 occurred 6 months after giving birth; underlying disorders were not identified in cases 2 or 3. The bleeding phenotype in these patients’ ranged from no bleeding tendency with isolated prolongation of APTT (activated partial thromboplastin time to severe intramuscular hematoma and hemarthrosis necessitating recombinant activated factor VII infusion and blood components transfusion. Variable responses to immunosuppressive treatment were also observed.

  5. Method of assessing heterogeneity in images

    Energy Technology Data Exchange (ETDEWEB)

    Jacob, Richard E.; Carson, James P.

    2016-08-23

    A method of assessing heterogeneity in images is disclosed. 3D images of an object are acquired. The acquired images may be filtered and masked. Iterative decomposition is performed on the masked images to obtain image subdivisions that are relatively homogeneous. Comparative analysis, such as variogram analysis or correlogram analysis, is performed of the decomposed images to determine spatial relationships between regions of the images that are relatively homogeneous.

  6. Facility for low-dose digital scanning of a large-area image of ionizing radiation

    International Nuclear Information System (INIS)

    The facility scans the unreduced X-ray image by means of moving line sensors which work in parallel. The length of the sensors is much smaller than the width of the image. The facility comprises about 20 identical modules, owing to which the output of the serial manufacture can be increased, and CCD-based line sensors can be employed which are very sensitive and inexpensive. The X-ray image can be taken at the virtually lowest exposure possible, and owing to the parallelization of the scanning process, the scanning rate can be increased considerably as compared with the existing facilities. The facility consists of an ionizing radiation source against which are positioned a movable diaphragm fitted with slits and a movable support plate carrying the line sensors. The sensors make up the line detector whose length is equal to that of the image scanned, synchronously movable with the movable slit diaphragm. (M.D.). 3 figs

  7. Evaluation of Serratia and Pseudomonas in hospital acquired infection

    OpenAIRE

    Etemadi H; Zahedani Sh

    1996-01-01

    Hospital acquired infection have 2 origins: 1) Infections acquired from the hospitalization. 2) Infections that transmit from hospital personnel and those who referred to a hospital. According to the studies approximately half of hospital acquired infection is under the first group. Gram-negative bacilli is of prime importance from all bacteries that caused hospital acquired infection. There are 3 main ways spreading hospital acquired infections include: 1) Auto infections 2) Transmit infecti...

  8. Acquired prosopagnosia without word recognition deficits.

    Science.gov (United States)

    Susilo, Tirta; Wright, Victoria; Tree, Jeremy J; Duchaine, Bradley

    2015-01-01

    It has long been suggested that face recognition relies on specialized mechanisms that are not involved in visual recognition of other object categories, including those that require expert, fine-grained discrimination at the exemplar level such as written words. But according to the recently proposed many-to-many theory of object recognition (MTMT), visual recognition of faces and words are carried out by common mechanisms [Behrmann, M., & Plaut, D. C. ( 2013 ). Distributed circuits, not circumscribed centers, mediate visual recognition. Trends in Cognitive Sciences, 17, 210-219]. MTMT acknowledges that face and word recognition are lateralized, but posits that the mechanisms that predominantly carry out face recognition still contribute to word recognition and vice versa. MTMT makes a key prediction, namely that acquired prosopagnosics should exhibit some measure of word recognition deficits. We tested this prediction by assessing written word recognition in five acquired prosopagnosic patients. Four patients had lesions limited to the right hemisphere while one had bilateral lesions with more pronounced lesions in the right hemisphere. The patients completed a total of seven word recognition tasks: two lexical decision tasks and five reading aloud tasks totalling more than 1200 trials. The performances of the four older patients (3 female, age range 50-64 years) were compared to those of 12 older controls (8 female, age range 56-66 years), while the performances of the younger prosopagnosic (male, 31 years) were compared to those of 14 younger controls (9 female, age range 20-33 years). We analysed all results at the single-patient level using Crawford's t-test. Across seven tasks, four prosopagnosics performed as quickly and accurately as controls. Our results demonstrate that acquired prosopagnosia can exist without word recognition deficits. These findings are inconsistent with a key prediction of MTMT. They instead support the hypothesis that face

  9. Heterotopic ossification (myositis ossificans) in acquired immune deficiency syndrome. Detection by gallium scintigraphy

    International Nuclear Information System (INIS)

    A case of heterotopic ossification (myositis ossificans) secondary to the central nervous system complications of acquired immune deficiency syndrome (AIDS) is reported. Because of the overwhelming suspicion of infection in this patient, this diagnosis was not considered until a gallium scan revealed the typical findings of heterotopic ossification. Because of the increasing utilization of gallium imaging in the AIDS population, every imaging specialist should be aware of this potential disorder

  10. Nontropical pyomyositis as a cause of subacute, multifocal myalgia in the acquired immunodeficiency syndrome

    International Nuclear Information System (INIS)

    We report a case of nontropical pyomyositis in a patient with acquired immunodeficiency syndrome and disseminated Mycobacterium avium infection, in which severe myalgia was the presenting symptom over several weeks. Multifocal muscle lesions were identified by gallium scanning and magnetic resonance imaging techniques. The epidemiology, possible pathogenesis, clinical features, diagnostic imaging, and therapy are reviewed. Early suspicion of nontropical pyomyositis in severely immunocompromised patients with cryptic myalgia is recommended

  11. [Acquired immunodeficiency syndrome in pediatric patients].

    Science.gov (United States)

    Molina Moguel, J L; Ruiz Illezcas, R; Forsbach Sánchez, S; Carreño Alvarez, S; Picco Díaz, I

    1990-12-01

    The object of this study was to determine how many of the patients treated at the Pediatric Odontology Clinic, a branch of the Maxillo-Facial Surgery Service at the Veinte de Noviembre Regional Hospital, ISSSTE, are VIH-positive of show serious manifestations of Acquired Immuno-Deficiency Syndrome (AIDS). For such purpose, 100 pediatric patients suffering from different systemic or local diseases were evaluated, the most common being hematological alterations. Results evidenced the presence of VIH in the blood of five of the pediatric subjects, all suffering from Hemophilia. PMID:2132469

  12. Expert games: means to acquire expert knowledge

    Directory of Open Access Journals (Sweden)

    G. Ginkul

    1993-06-01

    Full Text Available This article describes the idea and use of non-traditional technique designed to acquire Expert's knowledge for Expert Systems. The procedures, called "Expert Games", look outwardly as well-known computer "playthings" and at the same time are strong means for Knowledge Acquisition. If Expert wants to succeed, he must to use his professional knowledge. After analyzing game operations of an Expert it is possible to resolve reverse problem - to define which what kind of knowledge have been used for making Expert's decision during the game.

  13. Acquired Congenital Malalignment of the Great Toenails

    Science.gov (United States)

    Decker, Ashley; Scher, Richard K.; Avarbock, Andrew

    2016-01-01

    Congenital malalignment is the lateral deviation of the nail plate along the longitudinal axis due to the lateral rotation of the nail matrix. The nail plate grows out in ridges caused by repeated microtrauma to the nail. Common complications include onychomycosis, Pseudomonas infection and acute or chronic paronychia. Treatment options range from conservative management to surgical options including realignment and nail matrixectomy. Congenital malalignment usually presents in infancy or childhood, but we present two cases of acquired malalignment occurring in the teenage years. PMID:27171597

  14. Performance evaluation of CCD- and mobile-phone-based near-infrared fluorescence imaging systems with molded and 3D-printed phantoms

    Science.gov (United States)

    Wang, Bohan; Ghassemi, Pejhman; Wang, Jianting; Wang, Quanzeng; Chen, Yu; Pfefer, Joshua

    2016-03-01

    Increasing numbers of devices are emerging which involve biophotonic imaging on a mobile platform. Therefore, effective test methods are needed to ensure that these devices provide a high level of image quality. We have developed novel phantoms for performance assessment of near infrared fluorescence (NIRF) imaging devices. Resin molding and 3D printing techniques were applied for phantom fabrication. Comparisons between two imaging approaches - a CCD-based scientific camera and an NIR-enabled mobile phone - were made based on evaluation of the contrast transfer function and penetration depth. Optical properties of the phantoms were evaluated, including absorption and scattering spectra and fluorescence excitation-emission matrices. The potential viability of contrastenhanced biological NIRF imaging with a mobile phone is demonstrated, and color-channel-specific variations in image quality are documented. Our results provide evidence of the utility of novel phantom-based test methods for quantifying image quality in emerging NIRF devices.

  15. Asian elephants acquire inaccessible food by blowing.

    Science.gov (United States)

    Mizuno, Kaori; Irie, Naoko; Hiraiwa-Hasegawa, Mariko; Kutsukake, Nobuyuki

    2016-01-01

    Many animals acquire otherwise inaccessible food with the aid of sticks and occasionally water. As an exception, some reports suggest that elephants manipulate breathing through their trunks to acquire inaccessible food. Here, we report on two female Asian elephants (Elephas maximus) in Kamine Zoo, Japan, who regularly blew to drive food within their reach. We experimentally investigated this behaviour by placing foods in inaccessible places. The elephants blew the food until it came within accessible range. Once the food was within range, the elephants were increasingly less likely to blow as the distance to the food became shorter. One subject manipulated her blowing duration based on food distance: longer when the food was distant. These results suggest that the elephants used their breath to achieve goals: that is, they used it not only to retrieve the food but also to fine-tune the food position for easy grasping. We also observed individual differences in the elephants' aptitude for this technique, which altered the efficiency of food acquisition. Thus, we added a new example of spontaneous behaviour for achieving a goal in animals. The use of breath to drive food is probably unique to elephants, with their dexterous trunks and familiarity with manipulating the act of blowing, which is commonly employed for self-comfort and acoustic communication. PMID:26541597

  16. Clinicopathological correlation of acquired hyperpigmentary disorders

    Directory of Open Access Journals (Sweden)

    Anisha B Patel

    2013-01-01

    Full Text Available Acquired pigmentary disorders are group of heterogenous entities that share single, most significant, clinical feature, that is, dyspigmentation. Asians and Indians, in particular, are mostly affected. Although the classic morphologies and common treatment options of these conditions have been reviewed in the global dermatology literature, the value of histpathological evaluation has not been thoroughly explored. The importance of accurate diagnosis is emphasized here as the underlying diseases have varying etiologies that need to be addressed in order to effectively treat the dyspigmentation. In this review, we describe and discuss the utility of histology in the diagnostic work of hyperpigmentary disorders, and how, in many cases, it can lead to targeted and more effective therapy. We focus on the most common acquired pigmentary disorders seen in Indian patients as well as a few uncommon diseases with distinctive histological traits. Facial melanoses, including mimickers of melasma, are thoroughly explored. These diseases include lichen planus pigmentosus, discoid lupus erythematosus, drug-induced melanoses, hyperpigmentation due to exogenous substances, acanthosis nigricans, and macular amyloidosis.

  17. Tetracycline resistance genes acquired at birth.

    Science.gov (United States)

    Alicea-Serrano, Angela M; Contreras, Mónica; Magris, Magda; Hidalgo, Glida; Dominguez-Bello, Maria G

    2013-06-01

    Newborns acquire their first microbiota at birth. Maternal vaginal or skin bacteria colonize newborns delivered vaginally or by C-section, respectively (Dominguez-Bello et al. 2010 #884). We aimed to determine differences in the presence of four tetracycline (tet) resistance genes, in the microbes of ten newborns and in the mouth and vagina of their mothers, at the time of birth. DNA was amplified by PCR with primers specific for [tet(M), tet(O), tet(Q), and tet(W)]. Maternal vaginas harbored all four tet resistance genes, but most commonly tet(M) and tet(O) (63 and 38 %, respectively). Genes coding for tet resistance differed by birth mode, with 50 % of vaginally delivered babies had tet(M) and tet(O) and 16 and 13 % of infants born by C-section had tet(O) and tet(W), respectively. Newborns acquire antibiotic resistance genes at birth, and the resistance gene profile varies by mode of delivery. PMID:23483141

  18. Clinicopathological correlation of acquired hyperpigmentary disorders.

    Science.gov (United States)

    Patel, Anisha B; Kubba, Raj; Kubba, Asha

    2013-01-01

    Acquired pigmentary disorders are group of heterogenous entities that share single, most significant, clinical feature, that is, dyspigmentation. Asians and Indians, in particular, are mostly affected. Although the classic morphologies and common treatment options of these conditions have been reviewed in the global dermatology literature, the value of histpathological evaluation has not been thoroughly explored. The importance of accurate diagnosis is emphasized here as the underlying diseases have varying etiologies that need to be addressed in order to effectively treat the dyspigmentation. In this review, we describe and discuss the utility of histology in the diagnostic work of hyperpigmentary disorders, and how, in many cases, it can lead to targeted and more effective therapy. We focus on the most common acquired pigmentary disorders seen in Indian patients as well as a few uncommon diseases with distinctive histological traits. Facial melanoses, including mimickers of melasma, are thoroughly explored. These diseases include lichen planus pigmentosus, discoid lupus erythematosus, drug-induced melanoses, hyperpigmentation due to exogenous substances, acanthosis nigricans, and macular amyloidosis. PMID:23619441

  19. The acquired hyperostosis syndrome. Pt. 2

    International Nuclear Information System (INIS)

    In the second part of this publication, we describe some additional findings in cases of sternocostoclavicular hyperostosis (SCCH). These include focal hyperostosis of the spine, in the pelvis and in the extremities and psoriatric skin lesions and severe forms of acne (acne conglobata, acne fulminans). An analysis of our 13 patients and of the relevant literature indicates that the hyperostosis is due to increased bone metabolism and heterotopic ossification of fibrous tissue and that these are the pathogenic bases of the changes in the axial skeleton, the pelvis and the bones of the extremities. We have suggested a scheme which would categorise the syndrom into complete, incomplete and possibly acquired forms. (orig./GDG)

  20. How to divest acquired physician practices.

    Science.gov (United States)

    O'Hare, P K

    1999-02-01

    When an integrated delivery system (IDS) determines it must divest itself of a previously acquired physician practice, it must manage the transaction with care. The IDS most likely will want to maintain a positive ongoing relationship with the physician practice, while avoiding concessions to the practice that could be construed as violations of state and Federal laws. Before proceeding, the IDS should evaluate the reasons for divesting the practice, assess legal issues involved in terminating contracts with the practice, decide how to deal with the practice's assets and office facilities, consider whether covenants not to compete should be enforced, ensure continued access to essential medical records, consider whether to incorporate a "non-disparagement" clause in the termination agreement, and determine what mutual general releases may be necessary. PMID:10345614

  1. Human temporal bone findings in acquired hypothyroidism.

    Science.gov (United States)

    Hald, J; Milroy, C M; Jensen, K D; Parving, A

    1991-11-01

    Histological studies of the auditory organ in patients with acquired hypothyroidism are scarce. Thus the aim of the present study was to examine the temporal bones and the brain in subjects with hypothyroidism. Four temporal bones and two brains from clinically and biochemically hypothyroid subjects were removed and evaluated by light microscopy determine to the morphological changes and deposition of neutral and acid glycosaminoglycans. An audiogram from one of the patients showed a sensorineural hearing loss, which could be ascribed to occupational noise exposure. The study revealed histological changes compatible with age and infectious disease. No accumulation of neutral or acid glycosaminoglycans could be demonstrated in the temporal bones, or in the brains. PMID:1761939

  2. Time dysperception perspective for acquired brain injury

    Directory of Open Access Journals (Sweden)

    Federica ePiras

    2014-01-01

    Full Text Available Distortions of time perception are presented by a number of neuropsychiatric disorders. Here we survey timing abilities in clinical populations with acquired brain injuries in key cerebral areas recently implicated in human studies of timing. We purposely analyzed the complex relationship between cognitive and contextual factors involved in time estimation, as to characterize the correlation between timed and other cognitive behaviors in each group. We assume that interval timing is a solid construct to study cognitive dysfunctions following brain injury, as timing performance is a sensitive metric of information processing, while temporal cognition has the potential of influencing a wide range of cognitive processes. Moreover, temporal performance is a sensitive assay of damage to the underlying neural substrate after a brain insult. Further research in neurological and psychiatric patients will definitively answer the question of whether time distortions are manifestations of cognitive and behavioral symptoms of brain damage and definitively clarify their mechanisms.

  3. Covalent targeting of acquired cysteines in cancer.

    Science.gov (United States)

    Visscher, Marieke; Arkin, Michelle R; Dansen, Tobias B

    2016-02-01

    The thiolate side chain of cysteine has a unique functionality that drug hunters and chemical biologists have begun to exploit. For example, targeting cysteine residues in the ATP-binding pockets of kinases with thiol-reactive molecules has afforded increased selectivity and potency to drugs like imbrutinib, which inhibits the oncogene BTK, and CO-1686 and AZD9291 that target oncogenic mutant EGFR. Recently, disulfide libraries and targeted GDP-mimetics have been used to selectively label the G12C oncogenic mutation in KRAS. We reasoned that other oncogenes contain mutations to cysteine, and thus screened the Catalog of Somatic Mutations in Cancer for frequently acquired cysteines. Here, we describe the most common mutations and discuss how these mutations could be potential targets for cysteine-directed personalized therapeutics. PMID:26629855

  4. Acquired methaemoglobinaemia related to phenazopyridine ingestion.

    Science.gov (United States)

    Shahani, Lokesh; Sattovia, Stacy

    2012-01-01

    Methaemoglobin is an altered state of haemoglobin in which the ferrous ions of haeme are oxidised to the ferric state. This results in increased affinity to the bound oxygen and decreasing its availability to tissues. Most cases of methaemoglobinaemia are acquired, resulting from an increased methaemoglobin formation by various exogenous agents. The authors report an elderly patient presenting to the emergency department with a 1-month history of shortness of breath. Around the same time she had started using over-the-counter (OTC) phenazopyridine tablets for urinary symptoms. The patient was hypoxic and cyanotic; however, lacked evidence of hypoxaemia on the arterial blood gas. The presence of abnormal haemoglobin was suspected and confirmed by elevated levels of methaemoglobin. Phenazopyridine was proposed to be the likely aetiology of the methaemoglobinaemia, which the patient was not aware of. This case highlights the importance of always inquiring the OTC drug use especially in geriatric population. PMID:22987905

  5. The acquired immunodeficiency syndrome in gay men.

    Science.gov (United States)

    Jaffe, H W; Hardy, A M; Morgan, W M; Darrow, W W

    1985-11-01

    The acquired immunodeficiency syndrome (AIDS) is a major health problem for gay men in the United States. About three fourths of all reported cases have occurred in this population, and the number is projected to double in the next year. In Manhattan and San Francisco, AIDS is now the leading cause of premature mortality in men aged 25 to 44 years who have never married. In a sample of a cohort of gay men enrolled in a San Francisco clinic, 2.7% of the men had the syndrome and 26% had related conditions in 1984. Antibody to human T-lymphotropic virus, type III/lymphadenopathy-associated virus was found in sera from 67% of the men, including 58% of asymptomatic men. Behavioral factors associated with an increased risk of AIDS include large numbers of sexual partners, receptive anal intercourse, and "fisting." The adoption of safer lifestyles is currently the basis of attempts to control the syndrome in gay men. PMID:2996396

  6. In vivo mechanisms of acquired thymic tolerance

    DEFF Research Database (Denmark)

    Chen, W; Issazadeh-Navikas, Shohreh; Sayegh, M H; Khoury, S J

    1997-01-01

    Injection of antigen into the thymus of adult animals induces specific systemic tolerance, but the mechanisms of acquired thymic tolerance are not well understood. To investigate these mechanisms we used a model of intrathymic injection of ovalbumin (OVA) in BALB/c mice. We show an antigen......-specific decrease in proliferative responses to OVA, as well as a significant decrease in antigen-specific IL-2 secretion and IFN-gamma production by splenocytes and lymph node cells of tolerant mice. Addition of recombinant IL-2 in vitro reversed the defect in IFN-gamma production by cells from OVA-tolerized...... expansion of transferred CD4+ TCR transgenic cells in tolerant mice in vivo. There was an increase in clonotype-positive T cells in the thymus after immunization, confirming that activated T cells circulate through the thymus. Furthermore, thymectomy after intrathymic injection abrogates the effect of...

  7. [Merits of acquiring ISO15189 accreditation].

    Science.gov (United States)

    Kitagawa, Masami

    2010-01-01

    In Japan, an ISO15189 accreditation system was started in 2005. To date, 47 hospitals have been accredited. In this session, I will present the merits of acquiring accreditation regarding ISO15189 based on our experience. Our hospital has 263 beds. The Clinical Examination Section consists of 12 staff (including 5 part-time workers): 7 in change of sample examination and 5 in charge of physiological examination. The annual number of samples is approximately 150,000. Samples collected on health checkups account for 90%. To improve the quality and service, assessment by third persons has been positively utilized in our hospital. Accreditation regarding ISO9001, ISO14001, ISO27001, privacy mark, hospital function assessment, the functional assessment of "ningen-dock"/health checkup hospitals, labor/hygiene service function assessment, and ISO15189 has been acquired. Patients may not recognize ISO. So, it must be utilized, considering that the acquisition of accreditation is not a goal but a starting point. Furthermore, cost-performance should be improved to achieve utilization-related merits. It is important to not only acquire accreditation but also help clinical staff and patients become aware of some changes/merits. Patients may consult a hospital for the following reasons: confidence in the hospital, and the staffs kind/polite attitudes. Long-term management strategies should be established without pursuing only short-term profits. I will introduce several merits of acquiring accreditation regarding ISO15189. Initially, incidental conditions for bids and appeal points include accreditation regarding ISO15189. Our corporation has participated in some competitive bids regarding health checkup business. In some companies, the bid conditions included ISO acquisition. In our hospital, clinical trials have been positively carried out. For participation in trials, hospitals must pass an institutional examination. However, ISO acquisition facilitates the preparation of

  8. Acquiring Correct Knowledge for Natural Language Generation

    CERN Document Server

    Reiter, E; Sripada, S G; 10.1613/jair.1176

    2011-01-01

    Natural language generation (NLG) systems are computer software systems that produce texts in English and other human languages, often from non-linguistic input data. NLG systems, like most AI systems, need substantial amounts of knowledge. However, our experience in two NLG projects suggests that it is difficult to acquire correct knowledge for NLG systems; indeed, every knowledge acquisition (KA) technique we tried had significant problems. In general terms, these problems were due to the complexity, novelty, and poorly understood nature of the tasks our systems attempted, and were worsened by the fact that people write so differently. This meant in particular that corpus-based KA approaches suffered because it was impossible to assemble a sizable corpus of high-quality consistent manually written texts in our domains; and structured expert-oriented KA techniques suffered because experts disagreed and because we could not get enough information about special and unusual cases to build robust systems. We bel...

  9. Guidelines for prevention of hospital acquired infections

    Directory of Open Access Journals (Sweden)

    Yatin Mehta

    2014-01-01

    Full Text Available These guidelines, written for clinicians, contains evidence-based recommendations for the prevention of hospital acquired infections Hospital acquired infections are a major cause of mortality and morbidity and provide challenge to clinicians. Measures of infection control include identifying patients at risk of nosocomial infections, observing hand hygiene, following standard precautions to reduce transmission and strategies to reduce VAP, CR-BSI, CAUTI. Environmental factors and architectural lay out also need to be emphasized upon. Infection prevention in special subsets of patients - burns patients, include identifying sources of organism, identification of organisms, isolation if required, antibiotic prophylaxis to be used selectively, early removal of necrotic tissue, prevention of tetanus, early nutrition and surveillance. Immunodeficient and Transplant recipients are at a higher risk of opportunistic infections. The post tranplant timetable is divided into three time periods for determining risk of infections. Room ventilation, cleaning and decontamination, protective clothing with care regarding food requires special consideration. Monitoring and Surveillance are prioritized depending upon the needs. Designated infection control teams should supervise the process and help in collection and compilation of data. Antibiotic Stewardship Recommendations include constituting a team, close coordination between teams, audit, formulary restriction, de-escalation, optimizing dosing, active use of information technology among other measure. The recommendations in these guidelines are intended to support, and not replace, good clinical judgment. The recommendations are rated by a letter that indicates the strength of the recommendation and a Roman numeral that indicates the quality of evidence supporting the recommendation, so that readers can ascertain how best to apply the recommendations in their practice environments.

  10. Does Acquired Hypothyroidism Affect the Hearing Functions?

    Directory of Open Access Journals (Sweden)

    Ayşe Arduç

    2015-12-01

    Full Text Available Purpose: It is well known that congenital hypothyroidism can cause hearing loss. However, conflicting results were found in studies investigating hearing functions in acquired hypothyroidism. Therefore, we evaluated the audiometric findings in patients with acquired hypothyroidism. Material and Method: The study included 58 patients with hypothyroidism and age- and gender-matched 34 healthy controls. Twenty eight (48.27% patients had subclinical hypothyroidism, and 30 (51.73% had obvious hypothyroidism. All subjects had a normal otoscopic examination and tympanometry. Pure tone audiometry at 250, 500, 1000, 2000, 4000, 6000, and 8000 Hertz (Hz was performed in both groups. Blood pressure measurements and the levels of plasma electrolytes, lipids and vitamin B12 were available in all subjects. Results: Hypothyroidism group and control group were similar with respect to systolic and diastolic blood pressures and plasma glucose, lipid, vitamin B12, calcium, sodium, potassium, and chloride levels. Significantly higher audiometric thresholds (dB at 250 (10 (0-45 vs. 5 (0-15, p<0.001 and 500 Hz (10 (0-40 vs. 10 (-5-15, p=0.003 were recorded in hypothyroid patients compared to that in healthy controls. Hearing thresholds at 250 and 500 Hz correlated positively with thyroid-stimulating hormone (TSH, and negatively with free triiodothyronine and free thyroxine. Subclinical hypothyroid patients had a higher hearing threshold at 250 Hz than healthy controls (p=0.001. Discussion: Our study demonstrated that hearing ability decreases in hypothyroidism, even in subclinical hypothyroidism. The changes in TSH and thyroid hormone levels seem to be directly related to the hearing loss in this population of patients.

  11. Focal parenchymal lesions in community-acquired bacterial meningitis in adults: a clinico-radiological study

    International Nuclear Information System (INIS)

    Here, we analyzed the frequency, morphological pattern, and imaging characteristics of focal lesions as a consequence of community-acquired bacterial meningitis. We hypothesized that diffusion-weighted imaging combined with contrast-enhanced imaging, serial scanning, and multimodal vascular studies would provide further insight into the pathological basis of such parenchymal lesions in bacterial meningitis. We reviewed clinical and imaging data (i.e., magnetic resonance tomography, magnetic resonance angiography, computed tomography angiography, digital subtraction angiography) of 68 adult patients admitted to our neurological intensive care unit between March 1998 and February 2009 with the diagnosis of community-acquired bacterial meningitis. We identified seven patients with parenchymal lesions. These lesions could be attributed to four morphological patterns: (1) territorial cerebral ischemia, (2) perforating vessels ischemia, (3) ischemia of presumed cardiac origin, and (4) isolated cortical lesions. Whereas the patterns (1) and (2) were associated with vasculopathy of large- and medium-sized vessels (as shown by cerebral vascular imaging), vessel imaging in (3) and (4) did not show abnormal findings. Our study implies that parenchymal lesions in acute bacterial meningitis are mainly ischemic and due to involvement of large-, medium-, and small-sized arteries of the brain. Diffusion-weighted imaging combined with conventional, CT-, or MR-based cerebral angiography revealed the underlying pathophysiological mechanisms in the majority of patients. Furthermore, we detected two patients with isolated bilateral cortical involvement and normal vessel imaging. These lesions might represent ischemia due to the involvement of small pial and intracortical arteries. (orig.)

  12. Focal parenchymal lesions in community-acquired bacterial meningitis in adults: a clinico-radiological study

    Energy Technology Data Exchange (ETDEWEB)

    Katchanov, Juri [Campus Charite Mitte, Charite, Department of Neurology, Berlin (Germany); University Hospital Charite, Campus Benjamin Franklin, Department of Neurology, Berlin (Germany); Siebert, Eberhard; Klingebiel, Randolf [Campus Charite Mitte, Charite, Department of Neuroradiology, Berlin (Germany); Endres, Matthias [Campus Charite Mitte, Charite, Department of Neurology, Berlin (Germany); Charite-Universitaetsmedizin Berlin, Center for Stroke Research Berlin, Berlin (Germany)

    2009-11-15

    Here, we analyzed the frequency, morphological pattern, and imaging characteristics of focal lesions as a consequence of community-acquired bacterial meningitis. We hypothesized that diffusion-weighted imaging combined with contrast-enhanced imaging, serial scanning, and multimodal vascular studies would provide further insight into the pathological basis of such parenchymal lesions in bacterial meningitis. We reviewed clinical and imaging data (i.e., magnetic resonance tomography, magnetic resonance angiography, computed tomography angiography, digital subtraction angiography) of 68 adult patients admitted to our neurological intensive care unit between March 1998 and February 2009 with the diagnosis of community-acquired bacterial meningitis. We identified seven patients with parenchymal lesions. These lesions could be attributed to four morphological patterns: (1) territorial cerebral ischemia, (2) perforating vessels ischemia, (3) ischemia of presumed cardiac origin, and (4) isolated cortical lesions. Whereas the patterns (1) and (2) were associated with vasculopathy of large- and medium-sized vessels (as shown by cerebral vascular imaging), vessel imaging in (3) and (4) did not show abnormal findings. Our study implies that parenchymal lesions in acute bacterial meningitis are mainly ischemic and due to involvement of large-, medium-, and small-sized arteries of the brain. Diffusion-weighted imaging combined with conventional, CT-, or MR-based cerebral angiography revealed the underlying pathophysiological mechanisms in the majority of patients. Furthermore, we detected two patients with isolated bilateral cortical involvement and normal vessel imaging. These lesions might represent ischemia due to the involvement of small pial and intracortical arteries. (orig.)

  13. A combined micro-PET/CT scanner for small animal imaging

    International Nuclear Information System (INIS)

    A micro-PET/CT system was developed by combination of an in-house micro-CT and a microPET[reg] R4 scanner. The cone-beam micro-CT consists of a rotational gantry that fits an X-ray tube, a CCD-based X-ray detector, and motor-driven linear stages. The gantry was designed to be coaxial with the scanner of microPET'' (registered) R4. It can be moved for the convenience of mounting the Ge-68 point-source holder for PET's calibration. The image volumes obtained from two modalities is registered by a pre-determined, inherent spatial transformation function. This hardware-approach fusion, which provides accurate and no labor-intensive alignment, is suitable for mass scanning. The micro-PET/CT system has been operated successfully. Merging the anatomical and functional images benefit studies of the small animal imaging

  14. Acquiring Control in Emerging Markets: Evidence from the Stock Market

    OpenAIRE

    Anusha Chari; Paige P. Ouimet; Tesar, Linda L.

    2004-01-01

    When firms from developed markets acquire firms in emerging markets, market-capitalization-weighted monthly joint returns show a statistically significant increase of 1.8%. Panel data estimations suggest that the value gains from cross-border M&A transactions stem from the transfer of majority control from emerging-market targets to developed market acquirers' joint returns range from 5.8% to 7.8% when majority control is acquired. Announcement returns for acquirer and target firms estimate t...

  15. Epicutaneous Model of Community-Acquired Staphylococcus aureus Skin Infections

    OpenAIRE

    Prabhakara, Ranjani; Foreman, Oded; De Pascalis, Roberto; Lee, Gloria M.; Plaut, Roger D.; Kim, Stanley Y.; Stibitz, Scott; Elkins, Karen L.; Merkel, Tod J.

    2013-01-01

    Staphylococcus aureus is one of the most common etiological agents of community-acquired skin and soft tissue infection (SSTI). Although the majority of S. aureus community-acquired SSTIs are uncomplicated and self-clearing in nature, some percentage of these cases progress into life-threatening invasive infections. Current animal models of S. aureus SSTI suffer from two drawbacks: these models are a better representation of hospital-acquired SSTI than community-acquired SSTI, and they involv...

  16. The influence of physical activity on body image in people with and without acquired mobility disability [Vliv pohybové aktivity na subjektivní vnímání těla u osob se získaným tělesným postižením a bez něj

    Directory of Open Access Journals (Sweden)

    Ziya Koruç

    2011-12-01

    Full Text Available BACKGROUND: Body image in people with physical disability is important, but it has received little attention in the research literature. OBJECTIVE: The aim of the study was to determine whether differences exist between adolescents with acquired mobility disability (AMD and those without AMD regarding body image, and whether physical activity influences these differences. METHODS: Fifty-eight adolescents, aged 16 to 18 years, participated in this study. Half the participants had some form of AMD while the other half were healthy. Body image was evaluated with the Multidimensional Body-Self Relations Questionnaire (MBSRQ before and after 6 weeks of playing darts. A two-way ANOVA was used to analyse the results. RESULTS: At the end of the study, the healthy adolescents scored significantly higher than the AMD group on the subscales of fitness perception, orientation and overall health perception. No interaction was found between disability and exercise on any subscales of the MBSRQ. CONCLUSIONS: The results of this study demonstrate that people with AMD evaluate their health and fitness levels as being lower than healthy adolescents and that they are less concerned with fitness as compared with healthy adolescents. Six weeks of playing darts as a physical activity had no effect on improving the self-perceptions of the AMD group.[VÝCHODISKA: Subjektivní vnímání těla u lidí s tělesným postižením je důležitý aspekt, v odborné literatuře mu však nebylo věnováno příliš pozornosti. CÍLE: Cílem studie bylo stanovit, zda se vyskytují rozdíly mezi adolescenty se získaným tělesným postižením (AMD a adolescenty bez AMD, co se týče subjektivního vnímání těla, a zda tyto rozdíly ovlivňuje pohybová aktivita. METODIKA: Této studie se zúčastnilo padesát osm adolescentů ve věku mezi 16 a 18 lety. Polovina účastníků měla některou z forem AMD, zatímco druhá polovina byla zdravá. Subjektivní vnímání t

  17. Mucocutaneous manifestations of acquired hypoparathyroidism: An observational study

    OpenAIRE

    Somenath Sarkar; Modhuchanda Mondal; Kapildev Das; Arpit Shrimal

    2012-01-01

    Hypoparathyroidism is a disorder of calcium and phosphorus metabolism due to decreased secretion of parathyroid hormone. Hypoparathyroidism can be hereditary and acquired. Acquired hypoparathyroidism usually occurs following neck surgery (thyroid surgery or parathyroid surgery). Along with systemic manifestations, hypoparathyroidism produces some skin manifestations. Lack of study regarding mucocutaneous manifestations of acquired hypoparathyroidism prompted us to undertake this study. To eva...

  18. 30 CFR 879.14 - Management of acquired land.

    Science.gov (United States)

    2010-07-01

    ... ABANDONED MINE LAND RECLAMATION ACQUISITION, MANAGEMENT, AND DISPOSITION OF LANDS AND WATER § 879.14 Management of acquired land. Land acquired under this part may be used for any lawful purpose that is... 30 Mineral Resources 3 2010-07-01 2010-07-01 false Management of acquired land. 879.14 Section...

  19. Preschoolers Acquire General Knowledge by Sharing in Pretense

    Science.gov (United States)

    Sutherland, Shelbie L.; Friedman, Ori

    2012-01-01

    Children acquire general knowledge about many kinds of things, but there are few known means by which this knowledge is acquired. In this article, it is proposed that children acquire generic knowledge by sharing in pretend play. In Experiment 1, twenty-two 3- to 4-year-olds watched pretense in which a puppet represented a "nerp" (an unfamiliar…

  20. Medical Image Fusion

    Directory of Open Access Journals (Sweden)

    Mitra Rafizadeh

    2007-08-01

    Full Text Available Technological advances in medical imaging in the past two decades have enable radiologists to create images of the human body with unprecedented resolution. MRI, PET,... imaging devices can quickly acquire 3D images. Image fusion establishes an anatomical correlation between corresponding images derived from different examination. This fusion is applied either to combine images of different modalities (CT, MRI or single modality (PET-PET."nImage fusion is performed in two steps:"n1 Registration: spatial modification (eg. translation of model image relative to reference image in order to arrive at an ideal matching of both images. Registration methods are feature-based and intensity-based approaches."n2 Visualization: the goal of it is to depict the spatial relationship between the model image and refer-ence image. We can point out its clinical application in nuclear medicine (PET/CT.

  1. Acquiring energy savings in manufactured housing

    International Nuclear Information System (INIS)

    In 1991, the Northwest utilities faced a complex situation. They needed new sources of electrical power to avoid future deficits. A significant block of energy savings was available in the manufactured housing sector in the form of energy savings from increased insulation to new manufactured homes. The manufacturers were interested in saving the electricity in the homes, but would only deal with the utility sector as a whole. Half of the homes targeted were sited in investor-owned utility (IOU) service territories, and half in the public sector made up of utilities that purchased some or all of their electricity from the Bonneville Power Administration. Utilities agreed to acquire energy from manufacturers In the form of thermal efficiency measures specified by the Bonneville Power Administration. The program that resulted from over one year of negotiations was called the Manufactured Housing Acquisition Program, or MAP. Manufacturers, the utilities, State Energy Offices, the Northwest Power Planning Council and Bonneville all worked closely and with tenacity to build the program that went into effect on April 1, 1992, and should save the region between 7 and 9 megawatts, enough energy to supply 11,000 homes in the Northwest

  2. Acquired Hemophilia A successfully treated with rituximab

    Directory of Open Access Journals (Sweden)

    Giovanni D'Arena

    2015-02-01

    Full Text Available Acquired hemophilia A (AHA is a rare bleeding disorder due to the development of specific autoantibodies against factor VIII. The anti-CD20 monoclonal antibody Rituximab has been proven to be effective in  obtaining a long-term suppression of inhibitors of AHA,  besides other immunosuppressive standard treatments. Here we describe a case of idiopathic AHA in a 60-year old man successfully treated with rituximab. He showed a complete clinical response with  a normalization of clotting  parameters after 5 weekly courses of rituximab given at a dose of 375 mg/sqm. , but after stopping rituximab, an initial worsening of coagulation  parameters  induced the addition of 3 further courses. At present, the patient is in complete clinical and hematological remission after 200 days.  This case confirms that Rituximab may be a safe and useful tool to treat AHA and, a prolonged administration can overcome the initial resistance. However, the precise position of this drug in the therapeutic strategy (first or second-line, alone or in combination with other drugs remains to be established and warrants further investigation.

  3. Recent legal problems in acquiring nuclear fuel

    International Nuclear Information System (INIS)

    This paper surveys problems encountered by Southern California Edison Company in acquiring U concentrates to meet the needs of San Onofre Nuclear Generating Station Units 1, 2, and 3. References are made to San Onofre, Edison, and San Diego Gas and Electric Company in order to illustrate certain legal problems. The San Onofre Units are owned 80% by Edison and 20% by San Diego. Questions are posed about the traditional fuel procurement practices. A subsidiary of Edison, Mono Power Company, locates and delivers energy resources for Edison. Mono and Rocky Mountain Energy Company are jointing developing the Bear Creek urnaium mining and milling complex. The risk involved in converting a joint venture to a partnership is pointed out. The purchasing arrangement in the Palo Verde participants is discussed. Market value is used as a basis for pricing future U deliveries, but there is no really satisfactory method for determining future market value. It is concluded that the purchaser of nuclear fuel is faced with legal problems that transcend conventional problems of contracts and the commercial code

  4. Epilepsy, Acquired Aphasia with Focal Cortical Dysplasia

    Directory of Open Access Journals (Sweden)

    Girija A.S

    1999-01-01

    Full Text Available A six year old boy having complex partial seizures with secondary generalization of four months duration developing isolated expressive dysphasia, later progressing to global aphasia is being reported. His awake EEG showed a left temporal spike wave discharge and sleep EEG showed continuous spike and ware discharges. MR imaging demonstrated focal cortical dysplasia in the left frontal and opercular region, a combination that has not been reported earlier.

  5. Relapsing malaria infection acquired in Kenya.

    OpenAIRE

    Patterson, J E; Bia, F. J.; Miller, K.; McPhedran, P.

    1987-01-01

    An American physician-traveler to East Africa presented with manifestations of cerebral malaria and was treated with intravenous quinidine for chloroquine-resistant falciparum malaria. He later relapsed with Plasmodium ovale infection, despite previous primaquine therapy. Treatment of chloroquine-resistant malaria is discussed. The difficulty in diagnosing P. ovale infections and the predominance of this malaria species over P. vivax in East Africa are reviewed. Images FIG. 1 FIG. 2 FIG. 3

  6. Cytomegalovirus retinitis associated with acquired immunodeficiency syndrome

    Institute of Scientific and Technical Information of China (English)

    GENG Shuang; YE Jun-jie; ZHAO Jia-liang; LI Tai-sheng; HAN Yang

    2011-01-01

    Background Cytomegalovirus (CMV) retinitis is the most severe intraocular complication that results in total retinal destruction and loss of visual acuity in patients with acquired immunodeficiency syndrome (AIDS). This study aimed to investigate the fundus characteristics, systemic manifestations and therapeutic outcomes of CMV retinitis associated with AIDS.Methods It was a retrospective case series. CMV retinitis was present in 39 eyes (25 patients). Best corrected visual acuities, anterior segment, fundus features, fundus fluorescence angiography (FFA) and CD4+ T-lymphocyte counts of the patients with CMV retinitis associated with AIDS were analyzed. Intravitreal injections of ganciclovir (400 μg) were performed in 4 eyes (2 patients).Results Retinal vasculitis, dense, full-thickness, yellow-white lesions along vascular distribution with irregular granules at the border, and hemorrhage on the retinal surface were present in 28 eyes. The vitreous was clear or mildly opaque.Late stage of the retinopathy was demonstrated in 8 eyes characterized as atrophic retina, sclerotic and attenuated vessels, retinal pigment epithelium (RPE) atrophy, and optic nerve atrophy. Retinal detachment was found in 3 eyes. The average CD4+ T-lymphocyte count in peripheral blood of the patients with CMV retinitis was (30.6±25.3) ×106/L (range,(0-85) × 106/L). After intravitreal injections of ganciclovir, visual acuity was improved and fundus lesions regressed.Conclusions CMV retinitis is the most severe and the most common intraocular complication in patients with AIDS. For the patients with yellow-white retinal lesions, hemorrhage and retinal vasculitis without clear cause, human immunodeficiency virus (HIV) serology should be performed. Routine eye examination is also indicated in HIV positive patients.

  7. Acute acquired comitant esotropia of childhood

    DEFF Research Database (Denmark)

    Hesgaard, Helena; Vinding, Troels

    2015-01-01

    : In all, 48 cases were recorded. The mean age at onset was 4.7 years, being significantly higher among children with intracranial disease. Seven cause-specific types of AACE in childhood were identified: The acute accommodative (n = 15, 31%), decompensated monofixation syndrome or esophoria (n = 13...... AACE and by review of literature, we identified seven cause-specific types of AACE. Intracranial disease was present in 6%, and four risk factors were identified to guide clinicians when to perform brain imaging. Findings suggest AACE of childhood to be differentiated from AACE of adulthood....

  8. New image measurements of the gravity wave propagation characteristics from a low latitude Indian station

    Directory of Open Access Journals (Sweden)

    M. Sivakandan

    2015-08-01

    Full Text Available The image observations of mesospheric O(1S 558 nm have been performed from a low latitude Indian station, Gadanki (13.5° N; 79.2° E using a CCD based all sky camera system. Based on three years (from year 2012 to the year 2014 of image data during March–April, we characterize the small scale gravity wave properties. We noted 50 strong gravity wave event and 19 ripple events to occur. The horizontal wavelengths of the gravity waves are found to vary from 12 to 42 km with the phase velocity ranging from 20 to 90 km. In most cases, these waves were propagating towards north with only a few occasions of southward propagation. The outgoing longwave radiation data suggest that lower atmospheric convection was most possible reason for the generation of the waves observed in the airglow data.

  9. Action observation and acquired motor skills: An fMRI study with expert dancers

    OpenAIRE

    Calvo-Merino, B.; Glaser, D.E.; Grezes, J.; Passingham, R. E.; Haggard, P

    2005-01-01

    When we observe someone performing an action, do our brains simulate making that action? Acquired motor skills offer a unique way to test this question, since people differ widely in the actions they have learned to perform. We used functional magnetic resonance imaging to study differences in brain activity between watching an action that one has learned to do and an action that one has not, in order to assess whether the brain processes of action observation are modulated by the expertise a...

  10. Residual fMRI sensitivity for identity changes in acquired prosopagnosia

    OpenAIRE

    Fox, Christopher J; Giuseppe eIaria; Duchaine, Bradley C.; Barton, Jason J.S.

    2013-01-01

    While a network of cortical regions contribute to face processing, the lesions in acquired prosopagnosia are highly variable, and likely result in different combinations of spared and affected regions of this network. To assess the residual functional sensitivities of spared regions in prosopagnosia, we designed a rapid event-related functional magnetic resonance imaging (fMRI) experiment that included pairs of faces with same or different identities and same or different expressions. By meas...

  11. Progressive multifocal leukoence-phalopathy presenting as homonymous hemianopia in a patient with acquired immunodeficiency syndrome

    Directory of Open Access Journals (Sweden)

    Amit Pandey

    2012-01-01

    Full Text Available We present a case of a Human Immunodeficiency Virus (HIV positive patient who was referred for retinal evaluation to rule out ophthalmic manifestations of Acquired Immunodeficiency Syndrome (AIDS. She complained of some disturbance in vision in both eyes. Fundus examination showed no abnormality. Perimetry, done to rule out optic nerve pathology, showed a left homonymous hemianopia. Magnetic Resonance Imaging (MRI scan showed features of Progressive Multifocal Leukoencephalopathy (PML. She had no other neurological symptoms or signs.

  12. Missile and aircraft field test data acquired with the rapid optical beam steering (ROBS) sensor system

    Science.gov (United States)

    MacDonald, Bruce; Dunn, Murray; Herr, David W.; Hyman, Howard; Leslie, Daniel H.; Lovern, Michael G.

    1997-08-01

    The ROBS instrument has recently acquired unique imagery of a missile intercepting an airborne drone target. We present a summary of that mission. We also present imagery of three airborne targets collected while the ROBS instrument simultaneously tracked all three aircraft. The recent test data highlights the capability of the ROBS instrument for autonomous acquisition, tracking, and imaging of multiple targets under field test conditions. We also describe improvements to the optical system currently underway.

  13. Evolution and sequlae of acquired lobar emphysema in a premature infant with cronic lung disease

    International Nuclear Information System (INIS)

    The evolution of acquired lobar emphysemain a premature infant with cronic pulmonary disease was demonstrated by serial radiological examinations using multiple imaging methods including plain radiography, serial computed tomography and radionuclide studies. Long term clinical and radiological followup is presented. The value of computed tomography in the evolution of patient is emphasized. The literature on the patho-physiological mechanism of the disease is reviewed. (author)

  14. A high resolution Small Field Of View (SFOV) gamma camera: a columnar scintillator coated CCD imager for medical applications

    International Nuclear Information System (INIS)

    We describe a high resolution, small field of view (SFOV), Charge Coupled Device (CCD) based camera for imaging small volumes of radionuclide uptake in tissues. The Mini Gamma Ray Camera (MGRC) is a collimated, scintillator-coated, low cost, high performance imager using low noise CCDs. The prototype MGRC has a 600 μm thick layer of columnar CsI(Tl) and operates in photon counting mode using a thermoelectric cooler to achieve an operating temperature of - 10deg C. Collimation was performed using a pin hole collimator. We have measured the spatial resolution, energy resolution and efficiency using a number of radioisotope sources including 140 keV gamma-rays from 99mTc in a specially designed phantom. We also describe our first imaging of a volunteer patient.

  15. Acquired pulmonary arteriovenous malformation secondary to hydatid cyst operation.

    Science.gov (United States)

    Gezer, S; Turut, H; Oz, G; Demirag, F; Tastepe, I

    2007-10-01

    Pulmonary arteriovenous malformations are abnormal communications between pulmonary arteries and pulmonary veins. The majority of the cases are congenital in origin, and acquired pulmonary arteriovenous malformations are very rare. We present a case here, which - to the best of our knowledge - is the first acquired pulmonary arteriovenous malformation secondary to a hydatid cyst operation in the literature, and we discuss the etiology, clinical presentation, diagnostic modalities and treatment of acquired pulmonary arteriovenous malformations. PMID:17902072

  16. Infrared upconversion hyperspectral imaging

    DEFF Research Database (Denmark)

    Kehlet, Louis Martinus; Tidemand-Lichtenberg, Peter; Dam, Jeppe Seidelin; Pedersen, Christian

    2015-01-01

    In this Letter, hyperspectral imaging in the mid-IR spectral region is demonstrated based on nonlinear frequency upconversion and subsequent imaging using a standard Si-based CCD camera. A series of upconverted images are acquired with different phase match conditions for the nonlinear frequency...... conversion process. From this, a sequence of monochromatic images in the 3.2-3.4 mu m range is generated. The imaged object consists of a standard United States Air Force resolution target combined with a polystyrene film, resulting in the presence of both spatial and spectral information in the infrared...... image. (C) 2015 Optical Society of America...

  17. Hemofilia A adquirida Acquired hemophilia A

    Directory of Open Access Journals (Sweden)

    Delfina Almagro Vázquez

    2010-12-01

    Full Text Available La hemofilia A adquirida (HAA es un trastorno hemorrágico poco frecuente caracterizado por la presencia de autoanticuerpos contra el factor VIII (FVIII circulante. Aproximadamente en la mitad de los casos se ha observado un grupo heterogéneo de procesos patológicos que incluyen, entre otros, enfermedades autoinmunes y malignas y durante el embarazo, parto y puerperio. Las manifestaciones hemorrágicas son variables y fundamentalmente de tipo cutáneo mucoso. El diagnóstico se basa en el hallazgo en un paciente con manifestaciones hemorrágicas, prolongación del tiempo parcial de tromboplastina activado (TPTA, disminución de la actividad del FVIII y presencia de inhibidores del FVIII. El tratamiento de HAA incluye el control de las manifestaciones hemorrágicas y la supresión de la producción del anticuerpo. El concentrado de factor VIIa recombinante (FVIIar y el concentrado de complejo protrombínico (CCPA se consideran el tratamiento antihemorrágico de primera línea. Como terapéutica alternativa, en algunos casos puede utilizarse el concentrado de FVIII, la plasmaféresis y la inmunoadsorción extracorpórea. La prednisona sola o asociada con la ciclofosfamida, constituye el tratamiento inmunosupresor de primera línea. En pacientes refractarios puede administrarse como terapéutica de segunda línea, el rituximab (anti-CD20. Con la azatiopina, la ciclosporina, la vincristina y el micofenolato de mofetil, se han obtenido resultados variables.Acquired hemophilia A (AHA is an uncommon hemorrhagic disorder characterized by presence of autoantibodies to circulating factor VIII. Approximately in half of cases it is noted a heterogeneous group of pathological processes including among others, autoimmune and malignant diseases and during pregnancy, labor and puerperium. Hemorrhagic manifestations are variable and mainly of mucous cutaneous type. Diagnosis is based on the finding of a patient presenting with hemorrhagic manifestations

  18. A new approach in the design of electronic portal imaging devices for portal dosimetry in radiotherapy.

    Science.gov (United States)

    Badel, J N; Partouche-Sebban, D; Abraham, I; Carrie, C

    2014-09-01

    A CCD-based EPID using new crystal-assembly X-ray (CAX) converters is investigated for radiotherapy dosimetry. The proposed EPID design consists in replacing the common phosphor X-ray converters of current CCD-based EPIDs with high-stopping-power CAX converters. A Test Imaging Device (TID), consisting of a 30-mm-thick CAX converter made of Bismuth Germanate (BGO), coupled to a highly sensitive CCD camera, was used to evaluate the accessible imaging and dosimetric performance of the proposed design. The system response to dose and its dependence on photon beam energy were investigated. The effects of ghosting, dose rate, field size and phantom thickness were evaluated as well. The same measurements were also performed with our clinically used aSi-EPID so that comparisons of performance could be directly inferred. The TID displayed no detectable ghosting or sensitivity to dose rate. Its response to MU exposure was found to be linear within about ±1%. The level of glare induced in the TID and the aSi-EPID were equivalent. The TID resolution was higher than that of the aSi-EPID on the axis, but was found to decrease with off-axis distance. Finally, the image quality, assessed on the basis of signal-to-noise ratio in low dose radiographs of the larynx of a patient, was higher for the TID. The imaging performance accessible with the TID proved to be satisfying and its dosimetric capability was found to be superior to that of the current aSi-EPID. PMID:24767869

  19. Radiological findings in three acquired immunodeficiency syndrome patients with Rhodococcus equi pneumonia

    International Nuclear Information System (INIS)

    Objective: To study the imaging appearances of Rhodococcus equi pneumonia in three patients with acquired immunodeficiency syndrome ( AIDS). Methods: Thoracic imaging appearances of' Rhodococcus equi pneumonia in three patients with AIDS were retrospectively analyzed. Results: The chest radiograph showed patchy consolidations and small nodules (n=3), large consolidations with multiple cavitations (n=2). CT showed large lobar or segmental consolidations with multiple cavitations (n=2), patchy consolidations (n=2), bronchiectasis (n=1), multiple small centrilobular nodules (n=2) and tree-in-bud patterns (n=2). Conclusion: The most common radiological findings in AIDS patients with Rhodococcus equi pulmonary infection are large consolidations with multiple cavitations and multiple centrilobular nodules. (authors)

  20. Interpolation Technique in Computed Tomography Image Visualisation(Short Communication)

    OpenAIRE

    Asha Tripathi; P. K. Khatri; G. L. Baheti; K. C. Songara

    2002-01-01

    An interpolation technique has been developed for generation of enlarged dataset from a limited one-dimesional acquired dataset for improving the image quality in quick-scan tomography. The effectiveness of the technique has been tested using data acquired from the first-generation. The CT images generated using this technique have been compared with the CT images generated from the acquired dataset for the same number of projections. The image quality has been improved on account of (...

  1. Statistical image processing and multidimensional modeling

    CERN Document Server

    Fieguth, Paul

    2010-01-01

    Images are all around us! The proliferation of low-cost, high-quality imaging devices has led to an explosion in acquired images. When these images are acquired from a microscope, telescope, satellite, or medical imaging device, there is a statistical image processing task: the inference of something - an artery, a road, a DNA marker, an oil spill - from imagery, possibly noisy, blurry, or incomplete. A great many textbooks have been written on image processing. However this book does not so much focus on images, per se, but rather on spatial data sets, with one or more measurements taken over

  2. Acquiring and maintaining competency in gastrointestinal endoscopy.

    Science.gov (United States)

    Dubé, Catherine; Rostom, Alaa

    2016-06-01

    In recent years, an important transformation has taken place in the field of gastrointestinal endoscopy training. Two important movements have helped initiate this transformation: patient centered quality and competency based training. Patient centered quality in endoscopy became an important focus for colorectal cancer screening programs, as it was acknowledged that colonoscopy services played a central role in the outcomes of screening. This prompted the need to close the quality loop through the development of innovative endoscopist training and upskilling programs. As well, the importance of leadership skills and leadership training was highlighted as a key factor in effective quality improvement. Competency-based training depends on well-defined goals of training and on the regular documentation and review of the learner's progress. This is facilitated by objective assessment and performance enhancing feedback, enabled by measurement tools that can provide a quantitative or qualitative assessment and identify areas in need of further development. Simulators and scope imagers can aid the acquisition of technical skills, particularly in the novice phase. These important advances in our evolving concepts around endoscopy training have also raised many questions, highlighting important knowledge gaps which, we hope, will be addressed in coming years. PMID:27345643

  3. SPOT Controlled Image Base 10 meter

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — SPOT Controlled Image Base 10 meter (CIB-10) is a collection of orthorectified panchromatic (grayscale) images. The data were acquired between 1986 and 1993 by the...

  4. The case of Geely acquiring Volvo Car : A study on low brand equity acquiring high brand equity

    OpenAIRE

    Zheng, Xiaoshu; Shi, Yuan

    2013-01-01

    Much previous research has studied high brand equity acquiring high brand equity or high brand equity acquiring low brand equity. However, very little research has been conducted to understand how that low brand equity acquiring high brand equity changes the low brand equity especially in China. This paper is on the case of Geely Group acquiring Volvo Car which was a typical acquisition of a high brand equity company by a low brand equity company. The aim of the paper is to verify whether thi...

  5. PATHOGENETIC MECHANISMS OF CHRONIC ACQUIRED TOXOPLASMOSIS

    Directory of Open Access Journals (Sweden)

    Kotsyna S.S.

    2015-05-01

    Full Text Available Introduction. Toxoplasma gondii is an intracellular protozoan that infects approximately one-third of the world’s population. Infection in human generally occurs through consuming food or drink contaminated with oocysts and tissue cysts from undercooked meat. Although latent infection with Toxoplasma gondii is among the most prevalent of human infections, it has been generally assumed that, except for congenital transmission, it is asymptomatic. Different conditions such as, number of parasite, virulence of the organism, genetic background, sex, and immunological status seem to affect the course of infection The demonstration that Toxoplasma infections can alter behavior, reproductive function in patients has led to a reconsideration of this assumption. During chronic acquired toxoplasmosis (САT identified the regularities of changes in the ratio of the immune system and the basal levels of sex hormones available informative methods, which made it possible to evaluate the severity of the flow chart and predict treatment outcome without resorting to complex research methods. Found that the host-parasite relationships and clinical manifestations of chronic toxoplasmosis depend largely on protective and adaptive responses and compensatory abilities of the human body. Material & methods. 112 patients attended in the 6 Department of Kharkiv Regional Infectious Diseases Hospital №22 (Department of Medical Parasitology and Tropical Diseases of Kharkiv Medical Academy of Postgraduate Education, in Kharkiv, Ukraine were enrolled in the study. Forty four patients (39,3±4,6% were male and sixty eight (60,7±4,6% were female. The age of the patients was 18 till 72 years. Results & discussion. All of 112 CAT patients had subjective clinical symptoms in various combinations: increased fatigue 99,1 ± 0,9%, headache and tiredness 95,5 ± 1,9%, pain in the liver 88,4 ± 3,1%, bitter taste in the mouth 93,8 ± 2,2%, muscle pain 81,3 ± 3,7% and joint pain

  6. Rotationally acquired 4D-optical coherence tomography of embryonic chick hearts using retrospective gating on the common central A-scan

    DEFF Research Database (Denmark)

    Thommes, Jan; Happel, Christoph M.; Thrane, Lars;

    2010-01-01

    In vivo analysis of cardiac physiology and non-invasive imaging of the beating early embryonic heart in 2 and 3D remain a challenge in cardiovascular development research. 3D-imaging of the beating heart relies on gating of the acquired images according to the cardiac cycle. Mostly ECG triggering...... complexity. More recently, retrospective gating technologies were described (2; 3). In these studies, a time series of 2D images at several positions along the heart volume was used to produce a time sequence of 3D volumes of the beating heart. Rearrangement and validation of the asynchronously acquired...

  7. 26 CFR 1.472-7 - Inventories of acquiring corporations.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 6 2010-04-01 2010-04-01 false Inventories of acquiring corporations. 1.472-7 Section 1.472-7 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Inventories § 1.472-7 Inventories of acquiring corporations....

  8. 26 CFR 1.471-9 - Inventories of acquiring corporations.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 6 2010-04-01 2010-04-01 false Inventories of acquiring corporations. 1.471-9 Section 1.471-9 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Inventories § 1.471-9 Inventories of acquiring corporations....

  9. 26 CFR 1.9002-6 - Acquiring corporation.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 13 2010-04-01 2010-04-01 false Acquiring corporation. 1.9002-6 Section 1.9002-6 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES General Actuarial Valuations § 1.9002-6 Acquiring corporation. Section 5(d) of...

  10. 33 CFR 211.2 - Authority to acquire real estate.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Authority to acquire real estate..., DEPARTMENT OF DEFENSE REAL ESTATE ACTIVITIES OF THE CORPS OF ENGINEERS IN CONNECTION WITH CIVIL WORKS PROJECTS Real Estate; General § 211.2 Authority to acquire real estate. (a) Congressional...

  11. Clinical aspects of acquired aphasia and dysarthria in childhood

    NARCIS (Netherlands)

    H.R. van Dongen (Hugo)

    1988-01-01

    textabstractFor the last decade, it has been a common clinical belief that the prognosis of acquired childhood aphasia is good. However, our own clinical experiences were rather conflicting on this point. As a consequence, we re-examined all the children (15) with an acquired aphasia who in a period

  12. Acquired Epiblepharon Treated by Lateral Orbital and fat Decompression

    OpenAIRE

    Radwan Almousa; Gangadhara Sundar

    2011-01-01

    Conventional lid surgery of acquired epiblepharon secondary to increased orbital volume can be result of under correction of the epiblepharon, because the increased orbital volume remains unaddressed. In this case report, we present a case of acquired epiblepharon, secondary to increased orbital volume, treated with orbital decompression.

  13. Significance of acquired diverticular disease of the vermiform appendix

    DEFF Research Database (Denmark)

    Kallenbach, Klaus; Hjorth, Sofie Vetli; Engel, Ulla;

    2012-01-01

    To assess the prevalence of acquired diverticulum of the appendix (DA), including incipient forms and its possible significance as a marker of local/regional neoplasms.......To assess the prevalence of acquired diverticulum of the appendix (DA), including incipient forms and its possible significance as a marker of local/regional neoplasms....

  14. Hospital-acquired and Community-acquired Uropathogens; Modelling of Infection

    Directory of Open Access Journals (Sweden)

    Aija ?ilevi?a

    2005-12-01

    Full Text Available Urinary tract infections are among the most common human infections. They may be community-acquired or nosocomial, and caused by a variety of microorganisms. In the present study, we analysed more than 4000 urine samples collected from in-patients and outpatients, and registered the differences in the etiological spectrum of agents. The most widespread uropathogens are gram-negative rods, from them E. coli, Klebsiella spp. and the non-fermentive genus Pseudomonas. Women are more intensively affected by E. coli. From gram-positive cocci, the leading agents are coagulase negative Staphylococci, followed by S. aureus. No differences were registered between the genders. Polyresistance among gram-negative uropathogens is high.

  15. Feasibility and Initial Performance of Simultaneous SPECT-CT Imaging Using a Commercial Multi-Modality Preclinical Imaging System

    OpenAIRE

    Osborne, Dustin R.; Derek W. Austin

    2015-01-01

    Multi-modality imaging provides coregistered PET-CT and SPECT-CT images; however such multi-modality workflows usually consist of sequential scans from the individual imaging components for each modality. This typical workflow may result in long scan times limiting throughput of the imaging system. Conversely, acquiring multi-modality data simultaneously may improve correlation and registration of images, improve temporal alignment of the acquired data, increase imaging throughput, and benefi...

  16. Acquiring 4D thoracic CT scans using a multislice helical method

    International Nuclear Information System (INIS)

    Respiratory motion degrades anatomic position reproducibility during imaging, necessitates larger margins during radiotherapy planning and causes errors during radiation delivery. Computed tomography (CT) scans acquired synchronously with the respiratory signal can be used to reconstruct 4D CT scans, which can be employed for 4D treatment planning to explicitly account for respiratory motion. The aim of this research was to develop, test and clinically implement a method to acquire 4D thoracic CT scans using a multislice helical method. A commercial position-monitoring system used for respiratory-gated radiotherapy was interfaced with a third generation multislice scanner. 4D cardiac reconstruction methods were modified to allow 4D thoracic CT acquisition. The technique was tested on a phantom under different conditions: stationary, periodic motion and non-periodic motion. 4D CT was also implemented for a lung cancer patient with audio-visual breathing coaching. For all cases, 4D CT images were successfully acquired from eight discrete breathing phases, however, some limitations of the system in terms of respiration reproducibility and breathing period relative to scanner settings were evident. Lung mass for the 4D CT patient scan was reproducible to within 2.1% over the eight phases, though the lung volume changed by 20% between end inspiration and end expiration (870 cm3). 4D CT can be used for 4D radiotherapy, respiration-gated radiotherapy, 'slow' CT acquisition and tumour motion studies

  17. An experimental study on the readability of digital images in the furcal bone defects

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Hyung Wuk; Hwang, Eui Hwan; Lee, Sang Rae [Kyunghee University College of Medicine, Seoul (Korea, Republic of)

    2003-06-15

    To evaluate and compare the efficacy of digital radiographic images in the detection of bone loss at the bifurcation area of the mandibular first molar with traditional film-based periapical radiographs. One dried human mandible with minimal periodontal bone loss around the first molar was selected and an artificial alveolar bone defect at the bifurcation area was serially prepared over 18 steps. Images were taken using a direct CCD-based system and with F-speed periapical films. The images were evaluated by seven interpreters (3 radiologists, 3 periodontologists, and 1 general dentist) using a 5-point confidence rating scale. The readability of both periapical radiographs and digital image increased as the size of the artificial lesion and exposure time increased (p<0.05). Periapical radiographs offered greater readability of smaller bone defects than digital images, and the coefficient of variation of mean score between periapical radiographs and digital images showed a significant difference. The experimental results indicate that a significant difference in the coefficient of variation of mean score exists between periapical radiographs and digital images, and that traditional film-based periapical images offer greater readability of smaller bone defects than digital images can presently offer.

  18. Rethinking responsibility in offenders with acquired paedophilia: punishment or treatment?

    Science.gov (United States)

    Gilbert, Frédéric; Focquaert, Farah

    2015-01-01

    This article reviews the current neurobiological literature on the aetiology of developmental and acquired paedophilia and examines what the consequences could be in terms of responsibility and treatment for the latter. Addressing the question of responsibility and punishment of offenders with acquired paedophilia from a neurobiological perspective is controversial. Consequently it is essential to avoid hasty conclusions based strictly on neurobiological abnormality justifications. This study establishes a distinction between developmental and acquired paedophilia. The article investigates whether offenders who fulfil the diagnosis of acquired paedophilia should be held fully responsible, particularly in cases where the offender's conduct appears to result from volitionally controlled behaviour that is seemingly incompatible with a neurological cause. Moreover, the article explores how responsibility can be compromised when offenders with acquired paedophilia have (partially) preserved moral knowledge despite their sexual disorder. The article then examines the option of offering mandatory treatment as an alternative to imprisonment for offenders with acquired paedophilia. Furthermore, the article addresses the ethical issues related to offering any form of quasi-coercive treatment as a condition of release. This study concludes that decisions to fully or partially excuse an individual who fulfil the diagnosis of acquired paedophilia should take all relevant information into account, both neurobiological and other environmental evidence, and should proceed on a careful case by case analysis before sentencing or offering treatment. PMID:25725545

  19. Imaging spectroscopy with the atomic force microscope

    OpenAIRE

    Baselt, David R.; Baldeschwieler, John D.

    1994-01-01

    Force curve imaging spectroscopy involves acquiring a force-distance curve at each pixel of an atomic force microscope image. Processing of the resulting data yields images of sample hardness and tip-sample adhesion. These images resemble Z modulation images and the sum of forward and reverse friction images, respectively, and like them exhibit a number of potentially misleading contrast mechanisms. In particular, XY tip motion has a pronounced effect on hardness images and the meniscus force...

  20. Digital Imaging Mass Spectrometry

    Science.gov (United States)

    Bamberger, Casimir; Renz, Uwe; Bamberger, Andreas

    2011-06-01

    Methods to visualize the two-dimensional (2D) distribution of molecules by mass spectrometric imaging evolve rapidly and yield novel applications in biology, medicine, and material surface sciences. Most mass spectrometric imagers acquire high mass resolution spectra spot-by-spot and thereby scan the object's surface. Thus, imaging is slow and image reconstruction remains cumbersome. Here we describe an imaging mass spectrometer that exploits the true imaging capabilities by ion optical means for the time of flight mass separation. The mass spectrometer is equipped with the ASIC Timepix chip as an array detector to acquire the position, mass, and intensity of ions that are imaged by matrix-assisted laser desorption/ionization (MALDI) directly from the target sample onto the detector. This imaging mass spectrometer has a spatial resolving power at the specimen of (84 ± 35) μm with a mass resolution of 45 and locates atoms or organic compounds on a surface area up to ~2 cm2. Extended laser spots of ~5 mm2 on structured specimens allows parallel imaging of selected masses. The digital imaging mass spectrometer proves high hit-multiplicity, straightforward image reconstruction, and potential for high-speed readout at 4 kHz or more. This device demonstrates a simple way of true image acquisition like a digital photographic camera. The technology may enable a fast analysis of biomolecular samples in near future.

  1. Meningitis and stridor in advanced Human immunodeficiency virus/acquired immune deficiency syndrome

    Directory of Open Access Journals (Sweden)

    Naidoo P

    2013-09-01

    Full Text Available P Naidoo, D Pillay, S SamanDepartment of Internal Medicine, Port Shepstone Regional Hospital, University of KwaZulu-Natal, South AfricaAbstract: A 37-year-old female presented confused with a preceding history of severe headache. After clinical examination and investigations, she was diagnosed with disseminated tuberculosis (including central nervous system involvement, and Human immunodeficiency virus/acquired immune deficiency syndrome. Her hospital stay was complicated. She developed stridor and a cerebrovascular accident with left hemiplegia. She died approximately 2 weeks after admission. The potential causes of her stridor included a mediastinal mass or a central mechanism secondary to tuberculosis meningitis. Limited resources precluded definitive imaging of the chest to rule out a mediastinal mass. Further, an autopsy was not done. Despite these limitations, this case is unique because it reports the presence of both stridor and tuberculosis meningitis in an adult patient.Keywords: Human immunodeficiency virus, acquired immune deficiency syndrome, meningitis, stridor, tuberculosis

  2. Normalizing and converting image DC data using scatter plot matching

    Science.gov (United States)

    Remote sensing image data from sources such as Landsat or airborne multispectral digital cameras are typically in the form of digital count (DC) values. To compare images acquired by the same sensor system on different dates, or images acquired by different sensor systems, it is necessary to correct...

  3. Examination of the Accuracy of Coding Hospital-Acquired...

    Data.gov (United States)

    U.S. Department of Health & Human Services — A new study, Examination of the Accuracy of Coding Hospital-Acquired Pressure Ulcer Stages, published in Volume 4, Issue 1 of the Medicare and Medicaid Research...

  4. A methodology for acquiring qualitative knowledge for probabilistic graphical models

    DEFF Research Database (Denmark)

    Kjærulff, Uffe Bro; Madsen, Anders L.

    2004-01-01

    We present a practical and general methodology that simplifies the task of acquiring and formulating qualitative knowledge for constructing probabilistic graphical models (PGMs). The methodology efficiently captures and communicates expert knowledge, and has significantly eased the model...

  5. The Impact of Hospital-Acquired Conditions on Medicare..

    Data.gov (United States)

    U.S. Department of Health & Human Services — According to findings reported in The Impact of Hospital-Acquired Conditions on Medicare Program Payments, published in Volume 4, Issue 4 of the Medicare and...

  6. [Differential diagnosis of pulmonary tuberculosis and community-acquired pneumonia].

    Science.gov (United States)

    Deĭkina, O N; Mishin, V Iu; Demikhova, O V

    2007-01-01

    The purpose of this investigation was to enhance the efficiency of differential diagnosis of pneumonia and pulmonary tuberculosis. A hundred and fifty-nine adult patients were examined. These included 78 patients with pulmonary tuberculosis and 81 with community-acquired p neumonia. The clinical features of infiltrative pulmonary tuberculosis (n = 48) and mild community-acquired pneumonia (n = 51) were compared. The course of caseous pneumonia (n = 30) was compared with that of moderate and severe community-acquired pneumonia (n = 30). Significant differences in the manifestations of the intoxication and bronchopulmonary syndrome were not found in patients with community-acquired pneumonia and infiltrative pulmonary tuberculosis. Physical studies showed that in patients with community-acquired pneumonia, moist rale (54.9%) and crepitation (11.8%) were prevalent, but in those with infiltrative tuberculosis rale was absent in 60.4% of cases and the pattern of respiration was unchanged in 79.2%. Chest X-ray studies indicated that in patients with community-acquired pneumonia, lower lobar inflammatory changes were predominant in 62.8% of cases whereas in those with infiltrative pulmonary tuberculosis the process was mainly bilateral (43.8%) with the presence of destructive changes (83.3%) and bronchogenic dissemination (66.7%). In patients with caseous pneumonia, the intoxication syndrome was more significant than in those with severe community-acquired pneumonia. Chest X-ray studies demonstrated that in patients with caseous pneumonia, specific changes were bilateral with the involvement of 2 lobes or more, with destruction and bronchogenic dissemination while in those with community-acquired pneumonia, the pulmonary processes were predominantly bilateral (76.6%) at the lower lobar site (36.7%). PMID:17338353

  7. Acquired Dyslexia in Japanese: Implications for Reading Theory

    OpenAIRE

    Sato, H

    2007-01-01

    Acquired dyslexia research has been conducted mainly on English neurological patients. A limited number of dyslexia studies on non-alphabetic orthographies are available. Classical case studies for acquired dyslexia in Japanese, which has two distinctive scripts (morphographic Kanji and phonographic Kana), reported 'script-dependent' dyslexia patterns. Although recent case studies showed 'script-independent' dyslexia patterns for surface and phonological dyslexia, a 'script-independent'...

  8. Empiric antibiotic choices for community-acquired biliary tract infections

    OpenAIRE

    Kuo-Kuan Chang; Chin-Lu Chang; Fang-Ting Tai; Chun-Hsiang Wang; Ruey-Chang Lin

    2014-01-01

    Background: The study was conducted to reveal the most appropriate empiric antibiotics for the treatment of community-acquired biliary tract infections (CA-BTI) at a regional hospital in Taiwan. Methods: The study was performed between October 1, 2010 and October 31, 2012. All positive bile culture results of presumptive community-acquired origins were collected. The associated etiologic microorganisms and their antimicrobial susceptibilities were analyzed. The appropriateness of empiric t...

  9. Communicative Language Teaching enable students to acquire communicative competence

    OpenAIRE

    2011-01-01

    English is the language of international affairs, cultures and economic systems. It is a language of wider communication. The main aim of the learners is to acquire the target language but it can be acquired easily only if the language is made use of in our daily affairs. In order to achieve that target communicative language teaching, it focuses on the language competency of the target language .Knowledge of the structure of the language is equally important in order to learn the language.

  10. Hospital acquired diarrhea in a burn center of Tehran

    OpenAIRE

    Faranak Alinejad; Mitra Barati; Mahbobe Satarzadeh Tabrisi; Mohsen Saberi

    2016-01-01

    Background and Objectives: Incidence of hospital-acquired diarrhea has increased rapidly and burn patients are at high risk of getting it. Infection with C. difficile is the most common cause of antibiotic associated diarrhea. The aim of this study was to determine the baseline characteristics and clinical presentation of hospital-acquired diarrhea and compare C. difficile and non-C. difficile diarrhea in burn patients treated at a burn center.Materials and Methods: During a 1-year study all ...

  11. Multinational Exploration of Acquired R&D Activities

    OpenAIRE

    Gammelgård, Jens

    2004-01-01

    This paper presents the results of a survey of 54 Danish multinational corporations that have acquired activities abroad. The role of the acquired R&D units was the focus of the survey, particularly with respect to the schism between basic and applied R&D, and the schism between autonomous and network R&D. This paper establishes the connection between a multinational corporation that follows a capability-motivated acquisition strategy and the R&D role new subsidiaries should pl...

  12. The Acquired Preparedness Model of Risk for Bulimic Symptom Development

    OpenAIRE

    Combs, Jessica L.; Smith, Gregory T.; Flory, Kate; Simmons, Jean R.; Hill, Kelly K.

    2010-01-01

    The authors applied person-environment transaction theory to test the acquired preparedness model of eating disorder risk. The model holds that (a) middle school girls high in the trait of ineffectiveness are differentially prepared to acquire high risk expectancies for reinforcement from dieting/thinness; (b) those expectancies predict subsequent binge eating and purging; and (c) the influence of the disposition of ineffectiveness on binge eating and purging is mediated by dieting/thinness e...

  13. A Search/Crawl Framework for Automatically Acquiring Scientific Documents

    OpenAIRE

    Gollapalli, Sujatha Das; Patel, Krutarth; Caragea, Cornelia

    2016-01-01

    Despite the advancements in search engine features, ranking methods, technologies, and the availability of programmable APIs, current-day open-access digital libraries still rely on crawl-based approaches for acquiring their underlying document collections. In this paper, we propose a novel search-driven framework for acquiring documents for scientific portals. Within our framework, publicly-available research paper titles and author names are used as queries to a Web search engine. Next, res...

  14. Intensive care unit-acquired weakness in the burn population.

    Science.gov (United States)

    Cubitt, Jonathan J; Davies, Menna; Lye, George; Evans, Janine; Combellack, Tom; Dickson, William; Nguyen, Dai Q

    2016-05-01

    Intensive care unit-acquired weakness is an evolving problem in the burn population. As patients are surviving injuries that previously would have been fatal, the focus of treatment is shifting from survival to long-term outcome. The rehabilitation of burn patients can be challenging; however, a certain subgroup of patients have worse outcomes than others. These patients may suffer from intensive care unit-acquired weakness, and their treatment, physiotherapy and expectations need to be adjusted accordingly. This study investigates the condition of intensive care unit-acquired weakness in our burn centre. We conducted a retrospective analysis of all the admissions to our burn centre between 2008 and 2012 and identified 22 patients who suffered from intensive care unit-acquired weakness. These patients were significantly younger with significantly larger burns than those without intensive care unit-acquired weakness. The known risk factors for intensive care unit-acquired weakness are commonplace in the burn population. The recovery of these patients is significantly affected by their weakness. PMID:26975787

  15. Landslide Mapping Using Imagery Acquired by a Fixed-Wing Uav

    Science.gov (United States)

    Rau, J. Y.; Jhan, J. P.; Lo, C. F.; Lin, Y. S.

    2011-09-01

    In Taiwan, the average annual rainfall is about 2,500 mm, about three times the world average. Hill slopes where are mostly under meta-stable conditions due to fragmented surface materials can easily be disturbed by heavy typhoon rainfall and/or earthquakes, resulting in landslides and debris flows. Thus, an efficient data acquisition and disaster surveying method is critical for decision making. Comparing with satellite and airplane, the unmanned aerial vehicle (UAV) is a portable and dynamic platform for data acquisition. In particularly when a small target area is required. In this study, a fixed-wing UAV that equipped with a consumer grade digital camera, i.e. Canon EOS 450D, a flight control computer, a Garmin GPS receiver and an attitude heading reference system (AHRS) are proposed. The adopted UAV has about two hours flight duration time with a flight control range of 20 km and has a payload of 3 kg, which is suitable for a medium scale mapping and surveying mission. In the paper, a test area with 21.3 km2 in size containing hundreds of landslides induced by Typhoon Morakot is used for landslides mapping. The flight height is around 1,400 meters and the ground sampling distance of the acquired imagery is about 17 cm. The aerial triangulation, ortho-image generation and mosaicking are applied to the acquired images in advance. An automatic landslides detection algorithm is proposed based on the object-based image analysis (OBIA) technique. The color ortho-image and a digital elevation model (DEM) are used. The ortho-images before and after typhoon are utilized to estimate new landslide regions. Experimental results show that the developed algorithm can achieve a producer's accuracy up to 91%, user's accuracy 84%, and a Kappa index of 0.87. It demonstrates the feasibility of the landslide detection algorithm and the applicability of a fixed-wing UAV for landslide mapping.

  16. LANDSLIDE MAPPING USING IMAGERY ACQUIRED BY A FIXED-WING UAV

    Directory of Open Access Journals (Sweden)

    J. Y. Rau

    2012-09-01

    Full Text Available In Taiwan, the average annual rainfall is about 2,500 mm, about three times the world average. Hill slopes where are mostly under meta-stable conditions due to fragmented surface materials can easily be disturbed by heavy typhoon rainfall and/or earthquakes, resulting in landslides and debris flows. Thus, an efficient data acquisition and disaster surveying method is critical for decision making. Comparing with satellite and airplane, the unmanned aerial vehicle (UAV is a portable and dynamic platform for data acquisition. In particularly when a small target area is required. In this study, a fixed-wing UAV that equipped with a consumer grade digital camera, i.e. Canon EOS 450D, a flight control computer, a Garmin GPS receiver and an attitude heading reference system (AHRS are proposed. The adopted UAV has about two hours flight duration time with a flight control range of 20 km and has a payload of 3 kg, which is suitable for a medium scale mapping and surveying mission. In the paper, a test area with 21.3 km2 in size containing hundreds of landslides induced by Typhoon Morakot is used for landslides mapping. The flight height is around 1,400 meters and the ground sampling distance of the acquired imagery is about 17 cm. The aerial triangulation, ortho-image generation and mosaicking are applied to the acquired images in advance. An automatic landslides detection algorithm is proposed based on the object-based image analysis (OBIA technique. The color ortho-image and a digital elevation model (DEM are used. The ortho-images before and after typhoon are utilized to estimate new landslide regions. Experimental results show that the developed algorithm can achieve a producer's accuracy up to 91%, user's accuracy 84%, and a Kappa index of 0.87. It demonstrates the feasibility of the landslide detection algorithm and the applicability of a fixed-wing UAV for landslide mapping.

  17. An Analysis of Pyramidal Image Fusion Techniques

    OpenAIRE

    Meek, T. R.

    1999-01-01

    This paper discusses the application of multiresolution image fusion techniques to synthetic aperture radar (SAR) and Landsat imagery. Results were acquired through the development and application of image fusion software to test images. The test images were fused using six image fusion techniques that are the combinations from three types of image decomposition algorithms (ratio of low pass [RoLP] pyramids, gradient pyramids, and morphological pyramids) and two types of fusion algorithms (se...

  18. Mucocutaneous manifestations of acquired hypoparathyroidism: An observational study

    Directory of Open Access Journals (Sweden)

    Somenath Sarkar

    2012-01-01

    Full Text Available Hypoparathyroidism is a disorder of calcium and phosphorus metabolism due to decreased secretion of parathyroid hormone. Hypoparathyroidism can be hereditary and acquired. Acquired hypoparathyroidism usually occurs following neck surgery (thyroid surgery or parathyroid surgery. Along with systemic manifestations, hypoparathyroidism produces some skin manifestations. Lack of study regarding mucocutaneous manifestations of acquired hypoparathyroidism prompted us to undertake this study. To evaluate the mucocutaneous manifestations of acquired hypoparathyroidism. An observational study done in a tertiary care hospital of Kolkata by comprehensive history taking, through clinical examination and relevant laboratory investigations. Twenty-one patients were included in the study. The commonest form of acquired hypoparathyroidism was neck surgery (thyroidectomy and parathyroidectomy operation. Mucocutaneous manifestations were present in 76.19% of patients. The most frequent mucocutaneous manifestation was found in the hairs like the loss of axillary hair (61.9%, loss of pubic hair (52.38%, coarsening of body hair (47.62%, and alopecia areata (9.52%. The nail changes noted were brittle and ridged nail, followed by onycholysis, onychosezia, and onychomedesis. The most common skin features were xerotic skin in 11 patients (52.38%, followed by pellagra-like skin pigmentation, pustular psoriasis and acne form eruption, bullous impetigo, etc. Mucosa was normal in all the cases excepting the one which showed oral candidiasis.

  19. CMOS Imaging Sensor Technology for Aerial Mapping Cameras

    Science.gov (United States)

    Neumann, Klaus; Welzenbach, Martin; Timm, Martin

    2016-06-01

    In June 2015 Leica Geosystems launched the first large format aerial mapping camera using CMOS sensor technology, the Leica DMC III. This paper describes the motivation to change from CCD sensor technology to CMOS for the development of this new aerial mapping camera. In 2002 the DMC first generation was developed by Z/I Imaging. It was the first large format digital frame sensor designed for mapping applications. In 2009 Z/I Imaging designed the DMC II which was the first digital aerial mapping camera using a single ultra large CCD sensor to avoid stitching of smaller CCDs. The DMC III is now the third generation of large format frame sensor developed by Z/I Imaging and Leica Geosystems for the DMC camera family. It is an evolution of the DMC II using the same system design with one large monolithic PAN sensor and four multi spectral camera heads for R,G, B and NIR. For the first time a 391 Megapixel large CMOS sensor had been used as PAN chromatic sensor, which is an industry record. Along with CMOS technology goes a range of technical benefits. The dynamic range of the CMOS sensor is approx. twice the range of a comparable CCD sensor and the signal to noise ratio is significantly better than with CCDs. Finally results from the first DMC III customer installations and test flights will be presented and compared with other CCD based aerial sensors.

  20. Comparison of diffuse hepatocellular carcinoma and intrahepatic cholangiocarcinoma using sequentially acquired gadolinium-enhanced and Resovist-enhanced MRI

    International Nuclear Information System (INIS)

    Purpose: The purpose of this study was to compare MRI findings of diffuse hepatocellular carcinoma (D-HCC) and intrahepatic cholangiocarcinoma (IHC) to identify characteristics of each. Materials and methods: We retrospectively analyzed MRI that consisted of unenhanced T1- and T2-weighted image, gadolinium (Gd)-enhanced dynamic image, and sequentially acquired Resovist-enhanced image from 29 patients with D-HCCs and 32 patients with IHC. Results: On T2-weighted imaging, D-HCCs usually appeared as poorly defined, infiltrative mildly hyperintense masses, whereas IHC appeared as well-defined, lobulated mildly hyperintense masses with areas of strong hyperintensity and hypointensity. On dynamic- and Resovist-enhanced T1-weighted MRIs, D-HCCs appeared as hypovascular and homogeneously hypointense or isointense masses with internal reticulation, whereas IHD appeared as centripetal enhancing masses with or without delayed central hyperintensity. Biliary dilatation was predominantly observed in the area adjacent to the IHC and in the intratumoral area of D-HCC. Portal venous tumor thrombus was observed in most of the D-HCC, and portal vein encasement was seen in 17 of the IHC. Conclusion: D-HCC and IHC exhibited characteristics of each at T1- and T2-weighted imaging, Gd-enhanced dynamic imaging, and sequentially acquired Resovist-enhanced T1-weighted imaging.

  1. Comparison of diffuse hepatocellular carcinoma and intrahepatic cholangiocarcinoma using sequentially acquired gadolinium-enhanced and Resovist-enhanced MRI

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Young Kon [Department of Diagnostic Radiology, Chonbuk National University Hospital and Medical School, Keum Am Dong, JeonJu (Korea, Republic of)], E-mail: jmyr@dreamwiz.com; Han, Young Min; Kim, Chong Soo [Department of Diagnostic Radiology, Chonbuk National University Hospital and Medical School, Keum Am Dong, JeonJu (Korea, Republic of)

    2009-04-15

    Purpose: The purpose of this study was to compare MRI findings of diffuse hepatocellular carcinoma (D-HCC) and intrahepatic cholangiocarcinoma (IHC) to identify characteristics of each. Materials and methods: We retrospectively analyzed MRI that consisted of unenhanced T1- and T2-weighted image, gadolinium (Gd)-enhanced dynamic image, and sequentially acquired Resovist-enhanced image from 29 patients with D-HCCs and 32 patients with IHC. Results: On T2-weighted imaging, D-HCCs usually appeared as poorly defined, infiltrative mildly hyperintense masses, whereas IHC appeared as well-defined, lobulated mildly hyperintense masses with areas of strong hyperintensity and hypointensity. On dynamic- and Resovist-enhanced T1-weighted MRIs, D-HCCs appeared as hypovascular and homogeneously hypointense or isointense masses with internal reticulation, whereas IHD appeared as centripetal enhancing masses with or without delayed central hyperintensity. Biliary dilatation was predominantly observed in the area adjacent to the IHC and in the intratumoral area of D-HCC. Portal venous tumor thrombus was observed in most of the D-HCC, and portal vein encasement was seen in 17 of the IHC. Conclusion: D-HCC and IHC exhibited characteristics of each at T1- and T2-weighted imaging, Gd-enhanced dynamic imaging, and sequentially acquired Resovist-enhanced T1-weighted imaging.

  2. Residual fMRI sensitivity for identity changes in acquired prosopagnosia

    Directory of Open Access Journals (Sweden)

    Christopher J Fox

    2013-10-01

    Full Text Available While a network of cortical regions contribute to face processing, the lesions in acquired prosopagnosia are highly variable, and likely result in different combinations of spared and affected regions of this network. To assess the residual functional sensitivities of spared regions in prosopagnosia, we designed a rapid event-related functional magnetic resonance imaging (fMRI experiment that included pairs of faces with same or different identities and same or different expressions. By measuring the release from adaptation to these facial changes we determined the residual sensitivity of face-selective regions-of-interest. We tested three patients with acquired prosopagnosia, and all three of these patients demonstrated residual sensitivity for facial identity changes in surviving fusiform and occipital face areas of either the right or left hemisphere, but not in the right posterior superior temporal sulcus. The patients also showed some residual capabilities for facial discrimination with normal performance on the Benton Facial Recognition Test, but impaired performance on more complex tasks of facial discrimination. We conclude that fMRI can demonstrate residual processing of facial identity in acquired prosopagnosia, that this adaptation can occur in the same structures that show similar processing in healthy subjects, and further, that this adaptation may be related to behavioral indices of face perception.

  3. Acquired auditory-visual synesthesia: A window to early cross-modal sensory interactions

    Directory of Open Access Journals (Sweden)

    Pegah Afra

    2009-01-01

    Full Text Available Pegah Afra, Michael Funke, Fumisuke MatsuoDepartment of Neurology, University of Utah, Salt Lake City, UT, USAAbstract: Synesthesia is experienced when sensory stimulation of one sensory modality elicits an involuntary sensation in another sensory modality. Auditory-visual synesthesia occurs when auditory stimuli elicit visual sensations. It has developmental, induced and acquired varieties. The acquired variety has been reported in association with deafferentation of the visual system as well as temporal lobe pathology with intact visual pathways. The induced variety has been reported in experimental and post-surgical blindfolding, as well as intake of hallucinogenic or psychedelics. Although in humans there is no known anatomical pathway connecting auditory areas to primary and/or early visual association areas, there is imaging and neurophysiologic evidence to the presence of early cross modal interactions between the auditory and visual sensory pathways. Synesthesia may be a window of opportunity to study these cross modal interactions. Here we review the existing literature in the acquired and induced auditory-visual synesthesias and discuss the possible neural mechanisms.Keywords: synesthesia, auditory-visual, cross modal

  4. Imaging in pulsatile tinnitus

    Energy Technology Data Exchange (ETDEWEB)

    Madani, G. [Radiology Department, St Mary' s Hospital, London (United Kingdom)], E-mail: gittamadani@yahoo.com; Connor, S.E.J. [Neuroradiology Department, King' s College Hospital, London (United Kingdom)

    2009-03-15

    Tinnitus may be continuous or pulsatile. Vascular lesions are the most frequent radiologically demonstrable cause of pulsatile tinnitus. These include congenital vascular anomalies (which may be arterial or venous), vascular tumours, and a variety of acquired vasculopathies. The choice of imaging depends on the clinical findings. If a mass is present at otoscopy, thin-section computed tomography (CT) is indicated. In the otoscopically normal patient, there is a range of possible imaging approaches. However, combined CT angiography and venography is particularly useful.

  5. REVIEW OF A CASE OF CHILD WITH ACQUIRED APHASIA

    Directory of Open Access Journals (Sweden)

    Silvana FILIPOVA

    2004-12-01

    Full Text Available Achieved children speech disabilities are manifested at certain level of development of speech from the age of 3 to 12 years. The speech disabilities with children from the age of one to three years have developmental and acquired characteristics. It is well-known when and why the disabilities occurr at acquired aphasia or disphasia.The child with acquired aphasia or disphasia has early brain impairements and a relative improvement happens with adequate treatment and prompt rehabilitation treatment. It is more obvious with children than with adults.This fast and complete rehabilitation happens due to the plastic character of child’s brain and the possibilities for intro-hemisphere and inter-hemisphere reorganization of speech functions in childhood.

  6. Tuberculosis and the acquired immune deficiency syndrome in South Brazil

    International Nuclear Information System (INIS)

    Tuberculosis and the acquired immune deficiency syndrome in South Brazil. The authors studied the incidence of tuberculosis in South Brazilian patients with acquired immune deficiency syndrome from January 1985 to June 1988. During this period, tuberculosis occurred in 10.3% of acquired immune deficiency syndrome patients. The socioeconomic conditions and the incidence of disease in the population were not confirmed as a potential risk for tuberculosis infection. Chest radiographs revealed pulmonary infiltrates in six patients, hilar and/or mediastinal adenopathy in three, and pleural effusion in two. The two remaining patients had pulmonary consolidation associated with other features. None of these patients presented pulmonary cavitation or radiographic findings of typical reactivation of pulmonary tuberculosis. (author)

  7. Acquired night blindness due to bad eating patterns.

    Science.gov (United States)

    Parafita-Fernández, A; Escalona-Fermín, M M; Sampil, M; Moraña, N; Viso, E; Fernández-Vila, P C

    2015-06-01

    We report a case of acquired night blindness in a developed country (Spain) without risk factors for nutritional deficiency disease or family history of hereditary retinal disease. A 76-year-old woman presented with acquired night blindness of 6-month progression. After a thorough inquiry about eating patterns she becomes suspicious of vitamin A low dietary intake, which is analytically confirmed and successfully treated. Despite being very uncommon in our environment and even more in patients without digestive problems, in a patient reporting acquired night blindness vitamin A deficiency should not be discarded until eating patterns have been investigated. It might be especially relevant in certain socioeconomic situations and eating disorders such as bulimia or anorexia nervosa. PMID:25804276

  8. Free Auricular Composite Graft for Acquired Nasal Stenosis

    Science.gov (United States)

    Riley, Charles A.; Lawlor, Claire M.; Gray, Mingyang Liu; Graham, H. Devon

    2016-01-01

    Background: Acquired nasal stenosis poses a reconstructive challenge for the facial plastic surgeon. Many surgical options are available, ranging from primary closure to skin grafts to free flap reconstruction for complex defects. The free auricular composite graft is a single-stage procedure that can be used to repair nasal vestibular stenosis causing nasal obstruction. Case Report: We present the case of a patient with acquired nasal stenosis as a result of prolonged nasal tampon placement secondary to severe epistaxis and subsequent nasal vestibular infection. Repair via auricular composite graft was successful, and we provide a thorough explanation of graft design and operative technique. Conclusion: Free auricular composite grafts can produce desirable functional and aesthetic outcomes and should be considered in patients presenting with acquired nasal stenosis. PMID:27303225

  9. Rotationally acquired four-dimensional optical coherence tomography of embryonic chick hearts using retrospective gating on the common central A-scan

    DEFF Research Database (Denmark)

    Happel, Christoph M.; Thommes, Jan; Thrane, Lars;

    2011-01-01

    We introduce a new method of rotational image acquisition for four-dimensional (4D) optical coherence tomography (OCT) of beating embryonic chick hearts. The rotational axis and the central A-scan of the OCT are identical. An out-of-phase image sequence covering multiple heartbeats is acquired at.......We demonstrate this approach and provide a video of a beating Hamburger and Hamilton stage 16 embryonic chick heart generated from a 4D OCT data set using rotational image acquisition....

  10. ACQUIRE: A data acquisition system for CAMAC on SUN workstation

    International Nuclear Information System (INIS)

    The data acquisition software package ACQUIRE been used for many years by the Princeton University Cyclotron Laboratory for nuclear physics research applications. This code has been ported to the SUN Sparc workstation and is fully functional, including block data transfers using an in crate Event Handler. A SCSI interface to CAMAC is utilized, and the device handling software has been developed in such a way that little modification was needed in the ACQUIRE code for the SUN implementation. The Higz X windows graphics package from CERN is used for data display

  11. [Features of morbidity community-acquired pneumonia among young recruits].

    Science.gov (United States)

    Serdukov, D U; Gordienko, A V; Kozlov, M S; Mikhailov, A A; Davydov, P A

    2015-10-01

    Were examined 3338 military personnel of the combined training center. 183 of them diagnosed community-acquired pneumonia, in 3155 focal and infiltrative changes in lung tissue were not identified. The analisys of prevalence been made among young recruits of the acute respiratory illness before arriving in part and at the assembly point, foci of chronic infection, smoking, low body weight. 511 military personnel arrived at the training center in the disease state with symptoms of acute respiratory illness. Examined the relationship these risk factor to the development of community-acquired pneumonia in this category of servicemen. PMID:26827502

  12. Microsoft Acquired Nokia in Unipolar Operating System Market

    OpenAIRE

    Netra Pal Singh

    2014-01-01

    The recent big tickets include Microsoft acquiring part of Nokia for US$ 7.2 billion, Verizon buy 45% stake in Vodafone for US$130 billion, Google acquiring Motorola for 12.5 billion. These buyouts are analyzed and commented by experts of the industry. This research paper attempted to collate their view in the context of Microsoft and Nokia deal on six parameters. These parameters are (i) reasons for the downfall of the Nokia market share, (ii) general comments of the experts, (iii) similarit...

  13. Digital Imaging Mass Spectrometry

    CERN Document Server

    Bamberger, Casimir; Bamberger, Andreas

    2011-01-01

    Methods to visualize the two-dimensional distribution of molecules by mass spectrometric imaging evolve rapidly and yield novel applications in biology, medicine, and material surface sciences. Most mass spectrometric imagers acquire high mass resolution spectra spot-by-spot and thereby scan the object's surface. Thus, imaging is slow and image reconstruction remains cumbersome. Here we describe an imaging mass spectrometer that exploits the true imaging capabilities by ion optical means for the time of flight mass separation. The mass spectrometer is equipped with the ASIC Timepix chip as an array detector to acquire the position, mass, and intensity of ions that are imaged by MALDI directly from the target sample onto the detector. This imaging mass spectrometer has a spatial resolving power at the specimen of (84\\pm35) \\mu m with a mass resolution of 45 and locates atoms or organic compounds on a surface area up to ~2 cm2. Extended laser spots of ~5 mm2 on structured specimens allowed parallel imaging of s...

  14. Computed tomography in the evaluation of acquired stenosis in the neonate

    Energy Technology Data Exchange (ETDEWEB)

    Faw, K.; Muntz, H.; Siegel, M.; Spector, G.

    1982-01-01

    We studied the feasibility of computed tomographic evaluation of the neonatal airway. Three neonatal larynges, removed at necroscopy, were examined by computed tomography. Good resolution of soft tissue, cartilage and airway lumen was obtained in these small specimens. On the basis of these findings two neonates with acquired subglottic stenosis were examined by endoscopy, soft tissue airway radiographs, and computed tomography. Measurements of radiation dose revealed that a computed tomographic study delivered 36% of the mean tissue dose of standard image intensifier fluoroscopy. Computed tomography and fluoroscopy both demonstrated the degree and length of this stenosis accurately. An advantage of CT over conventional imaging procedures was better definition of the cross sectional area of the airway.

  15. Computed tomography in the evaluation of acquired stenosis in the neonate

    International Nuclear Information System (INIS)

    We studied the feasibility of computed tomographic evaluation of the neonatal airway. Three neonatal larynges, removed at necroscopy, were examined by computed tomography. Good resolution of soft tissue, cartilage and airway lumen was obtained in these small specimens. On the basis of these findings two neonates with acquired subglottic stenosis were examined by endoscopy, soft tissue airway radiographs, and computed tomography. Measurements of radiation dose revealed that a computed tomographic study delivered 36% of the mean tissue dose of standard image intensifier fluoroscopy. Computed tomography and fluoroscopy both demonstrated the degree and length of this stenosis accurately. An advantage of CT over conventional imaging procedures was better definition of the cross sectional area of the airway

  16. Development of a high speed imaging microscope and new software for nuclear track detector analysis

    International Nuclear Information System (INIS)

    Automated digital imaging optical microscopy is widely used for diagnostic applications in the health care and biology fields and for routine inspection in industrial applications such as semiconductor fabrication. These applications require the imaging of large areas at high speed in order to obtain sufficient data for image processing with good statistics. Track detector analysis also benefits from the rapid acquisition of large areas on the detector surface. We have developed a new microscope system, the HSP-1000, for high speed image acquisition that uses a line sensor camera in place of a traditional CCD camera. Continuous, automatic focusing of the microscope is achieved by means of an optical pick-up system that provides fast feedback for control of distance between the objective and the image surface. Using transmitted light illumination, the microscope is able to digitize a 1cm2 area at 0.35μm/pixel resolution in ∼20s. As a result of continuous stage motion and continuous focusing, we have attained image acquisition speeds that are 50-100 times faster than conventional CCD-based microscope systems. In this paper, we describe a number of aspects of the microscope system including the use of the line sensor and the automatic focus system

  17. Measurement error analysis of three dimensional coordinates of tomatoes acquired using the binocular stereo vision

    Science.gov (United States)

    Xiang, Rong

    2014-09-01

    This study analyzes the measurement errors of three dimensional coordinates of binocular stereo vision for tomatoes based on three stereo matching methods, centroid-based matching, area-based matching, and combination matching to improve the localization accuracy of the binocular stereo vision system of tomato harvesting robots. Centroid-based matching was realized through the matching of the feature points of centroids of tomato regions. Area-based matching was realized based on the gray similarity between two neighborhoods of two pixels to be matched in stereo images. Combination matching was realized using the rough disparity acquired through centroid-based matching as the center of the dynamic disparity range which was used in area-based matching. After stereo matching, three dimensional coordinates of tomatoes were acquired using the triangle range finding principle. Test results based on 225 stereo images captured at the distances from 300 to 1000 mm of 3 tomatoes showed that the measurement errors of x coordinates were small, and can meet the need of harvesting robots. However, the measurement biases of y coordinates and depth values were large, and the measurement variation of depth values was also large. Therefore, the measurement biases of y coordinates and depth values, and the measurement variation of depth values should be corrected in the future researches.

  18. School Reentry for Children with Acquired Central Nervous Systems Injuries

    Science.gov (United States)

    Carney, Joan; Porter, Patricia

    2009-01-01

    Onset of acquired central nervous system (CNS) injury during the normal developmental process of childhood can have impact on cognitive, behavioral, and motor function. This alteration of function often necessitates special education programming, modifications, and accommodations in the education setting for successful school reentry. Special…

  19. The pilot workshop TOR and the experience acquired in reprocessing

    International Nuclear Information System (INIS)

    This report reviews the experience acquired by the Group CEA in the reprocessing and the fast reactor fuels. TOR Treatment of Fast Oxide is the present stage in the development of reprocessing installations; TOR is a pre-industrial installation and will allow to develop the main technical choices

  20. Purpura fulminans due to acquired protein C deficiency

    Directory of Open Access Journals (Sweden)

    Devdeep Mukherjee

    2015-01-01

    Full Text Available Purpura fulminans (PF may be the presenting symptom in a patient with protein C (PC deficiency. It is a hematological emergency and presents with extensive areas of hemorrhagic necrosis of the skin. PC deficiency is usually genetically inherited. However, we report a 1 year and 4 months boy, who presented with acquired PC deficiency possibly of postinfectious etiology and developed PF.

  1. Characteristics of Individuals with Congenital and Acquired Deaf-Blindness

    Science.gov (United States)

    Dalby, Dawn M.; Hirdes, John P.; Stolee, Paul; Strong, J. Graham; Poss, Jeff; Tjam, Erin Y.; Bowman, Lindsay; Ashworth, Melody

    2009-01-01

    Using a standardized assessment instrument, the authors compared 182 adults with congenital deaf-blindness and those with acquired deaf-blindness. They found that those with congenital deaf-blindness were more likely to have impairments in cognition, activities of daily living, and social interactions and were less likely to use speech for…

  2. Cognitive Rehabilitation for Children with Acquired Brain Injury

    Science.gov (United States)

    Slomine, Beth; Locascio, Gianna

    2009-01-01

    Cognitive deficits are frequent consequences of acquired brain injury (ABI) and often require intervention. We review the theoretical and empirical literature on cognitive rehabilitation in a variety of treatment domains including attention, memory, unilateral neglect, speech and language, executive functioning, and family involvement/education.…

  3. Practitioner Review: Cognitive Rehabilitation for Children with Acquired Brain Injury

    Science.gov (United States)

    Limond, Jenny; Leeke, Rachel

    2005-01-01

    Background: The need to address acquired cognitive impairments is increasing in child populations seen across a range of settings. However, current clinical practice following brain injury in children does not necessarily incorporate the use of cognitive rehabilitation models or techniques. The aim of this paper is to review the literature in this…

  4. Unexpected postpartum hemorrhage due to an acquired factor VIII inhibitor.

    Science.gov (United States)

    Paidas, Michael J; Hossain, Nazli

    2014-09-01

    Unexplained postpartum hemorrhage (PPH) refractory to standard hemostatic measures should trigger a heightened clinical suspicion of an acquired bleeding disorder. When hemostatic medical interventions and surgical procedures fail to control the bleeding, then significant postoperative blood loss, debilitating morbidity, loss of fertility, and death may occur. In the setting of an autoantibody inhibitor to factor VIII (FVIII), control of life-threatening PPH and avoidance of subsequent bleeding episodes depends on a timely and accurate diagnosis, prompt hemostatic treatment and eradication of FVIII inhibitors, and appropriate long-term patient care and management. Acquired postpartum hemophilia due to a FVIII inhibitor is a rare cause of PPH; however, delayed treatment can lead to increased maternal morbidity and mortality. Acquired FVIII inhibitors also pose an emerging bleeding threat to the neonate as a result of possible transplacental transfer of FVIII autoantibodies to the fetus during the last trimester of pregnancy. The purpose of this review is to increase awareness among hematologists and obstetricians/gynecologists regarding the occurrence of FVIII neutralizing autoantibodies as a cause of PPH, and emphasize the importance of collaboration between obstetrician/gynecologists and hematology specialists to optimize the diagnostic evaluation, treatment, and long-term management of women who experience PPH due to an acquired FVIII inhibitor. PMID:24338123

  5. Acquired TTP: ADAMTS13 meets the immune system

    NARCIS (Netherlands)

    N. Sorvillo

    2013-01-01

    Autoantibodies directed against ADAMTS13 prohibit the processing of VWF multimers, initiating a rare and life-threatening disorder called acquired thrombotic thrombocytopenic purpura (TTP). At present it is not clear why previously healthy individuals develop anti-ADAMTS13 antibodies. The studies de

  6. Grief and Needs of Adults with Acquired Visual Impairments

    Science.gov (United States)

    Murray, Shirley A.; McKay, Robert C.; Nieuwoudt, Johan M.

    2010-01-01

    This report aims to illuminate the complex phenomenon of grief and the needs experienced throughout the time course of their impairments by adults with acquired visual impairments. The study applied a phenomenological research strategy using 10 case studies of South African adults, visually impaired within and beyond six years. Qualitative…

  7. Antibiotic Treatment Strategies for Community-Acquired Pneumonia in Adults

    NARCIS (Netherlands)

    Postma, Douwe F.; Van Werkhoven, Cornelis H.; Van Elden, Leontine J R; Thijsen, Steven F T; Hoepelman, Andy I M; Kluytmans, Jan A J W; Boersma, Wim G.; Compaijen, Clara J.; Van Der Wall, Eva; Prins, Jan M.; Oosterheert, Jan J.; Bonten, Marc J M

    2015-01-01

    BACKGROUND The choice of empirical antibiotic treatment for patients with clinically suspected community-acquired pneumonia (CAP) who are admitted to non-intensive care unit (ICU) hospital wards is complicated by the limited availability of evidence. We compared strategies of empirical treatment (al

  8. A case of acquired Gitelman syndrome presenting as hypokalemic paralysis

    OpenAIRE

    Kulkarni, M.; Kadri, P.; Pinto, R.

    2015-01-01

    We report a case of a young female patient who presented with weakness of upper and lower limbs. On evaluation, she had hypokalemia, hypomagnesemia, metabolic alkalosis and hypocalciuria. Anti-Ro (SSA) antibody was positive. She had an acquired Gitelman syndrome due to primary Sjögren's syndrome (SS). SS presenting with features of Gitelman syndrome is very rare.

  9. A case of acquired Gitelman syndrome presenting as hypokalemic paralysis.

    Science.gov (United States)

    Kulkarni, M; Kadri, P; Pinto, R

    2015-01-01

    We report a case of a young female patient who presented with weakness of upper and lower limbs. On evaluation, she had hypokalemia, hypomagnesemia, metabolic alkalosis and hypocalciuria. Anti-Ro (SSA) antibody was positive. She had an acquired Gitelman syndrome due to primary Sjögren's syndrome (SS). SS presenting with features of Gitelman syndrome is very rare. PMID:26199478

  10. Learning through Business Games: Acquiring Competences within Virtual Realities

    Science.gov (United States)

    Fortmuller, Richard

    2009-01-01

    The didactic function of business games is often seen only in the development of sociocommunicative competences and general problem-solving strategies. An equally important aspect of business games lies in the acquirement of technical and problem-oriented knowledge, which is the focus of this article. Moreover, this knowledge dimension is further…

  11. Heat Stress Screening of Peanut Seedlings for Acquired Thermotolerance

    Science.gov (United States)

    The objective of this research was to develop a user-friendly and medium throughput laboratory protocol using acquired thermotolerance (ATT) in peanut seedlings as a measure of one mechanism of heat stress tolerance. Sixteen genotypes, including selected accessions of the U.S. peanut min...

  12. [Acquired agammaglobulinaemia with predominantly intestinal symptoms (author's transl)].

    Science.gov (United States)

    Goldach, R; Wittwer, J

    1977-11-01

    In a 45-year-old female patient primary acquired agammaglobulinaemia was diagnosed. Intestinal symptoms predominated. The disease was characterized by a B-cell defect. Substitution with gamma-globulin (Beriglobin) practically cured the symptoms. The pathogenesis of the disease remains unexplained. PMID:72639

  13. Idiopathic Acquired Hemophilia A with Undetectable Factor VIII Inhibitor

    Directory of Open Access Journals (Sweden)

    Nicholas B. Abt

    2014-01-01

    Full Text Available Objective. We present the case of a 73-year-old female, with no family or personal history of a bleeding disorder, who had a classic presentation for acquired hemophilia A. Factor VIII activity was low but detectable and a factor VIII inhibitor was undetectable. Methods. The patient’s plasma was comprehensively studied to determine the cause of the acquired coagulopathy. Using the Nijmegen modification of the Bethesda assay, no factor VIII autoantibody was measureable despite varying the incubation time from 1 to 3 hours. Results. The aPTT was prolonged at 46.8 seconds, which did not correct in the 4 : 1 mix but did with 1 : 1 mix. Using a one stage factor VIII activity assay, the FVIII activity was 16% and chromogenic FVIII activity was also 16%. The patient was treated with recombinant FVII and transfusion, significantly reducing bleeding. Long-term therapy was initiated with cyclophosphamide and prednisone with normalization of FVIII activity. Conclusions. Physicians can be presented with the challenging clinical picture of an acquired factor VIII inhibitor without a detectable inhibitor by the Bethesda assay. Standard therapy for an acquired hemophilia A should be considered.

  14. Acquiring Software Design Schemas: A Machine Learning Perspective

    Science.gov (United States)

    Harandi, Mehdi T.; Lee, Hing-Yan

    1991-01-01

    In this paper, we describe an approach based on machine learning that acquires software design schemas from design cases of existing applications. An overview of the technique, design representation, and acquisition system are presented. the paper also addresses issues associated with generalizing common features such as biases. The generalization process is illustrated using an example.

  15. Bleomycin Containing Chemotherapeutic Regimen Induced Acquired Partial Lipodystrophy

    Science.gov (United States)

    Tandon, Vishal R; Gupte, Novy; Mahajan, Vivek; Sharma, Rahul; Langer, Cheena; Khajuria, Vijay; Mahajan, Annil

    2016-01-01

    Bleomycin toxicity predominantly affects the skin and lungs. Cutaneous toxicity classically known to present with bleomycin are flagellate erythema and drug rash. We hereby report an isolated case of (bleomyicn)-induced acquired partial (lipodytrophy) having potential cosmetic implications in a young women prescribed postoperatively following a case of germ cell carcinoma of ovary (endodermal sinus tumor). PMID:26955139

  16. Hemorrhagic abscess in a patient with the acquired immunodeficiency syndrome

    International Nuclear Information System (INIS)

    Cerebral toxoplasmosis is frequent among patients with the acquired immunodeficiency syndrome. The common computed tomography appearance of this complication is multiple low density area with ring enhancement. We describe a very rare picture of cerebral toxoplasmosis, this is multiple hemorrhagic toxoplasmic abscess. (orig.)

  17. A Corpus-Based Comparative Study of "Learn" and "Acquire"

    Science.gov (United States)

    Yang, Bei

    2016-01-01

    As an important yet intricate linguistic feature in English language, synonymy poses a great challenge for second language learners. Using the 100 million-word British National Corpus (BNC) as data and the software Sketch Engine (SkE) as an analyzing tool, this article compares the usage of "learn" and "acquire" used in natural…

  18. On the difficulties of acquiring mathematical experience: Case rural education

    DEFF Research Database (Denmark)

    Booss-Bavnbek, Bernhelm

    2014-01-01

    Based on a variety of philosophical approaches and my own work for decades in pure and applied mathematics teaching and research, I explain my view upon the basic difficulties of acquiring the “Mathematical Experience” (in the sense of P.J. Davis and R. Hersh 1981) and submit a list of claims how...

  19. Acquired Dysarthria in Conversation: Identifying Sources of Understandability Problems

    Science.gov (United States)

    Bloch, Steven; Wilkinson, Ray

    2009-01-01

    Background: Acquired progressive dysarthria is traditionally assessed, rated, and researched using measures of speech perception and intelligibility. The focus is commonly on the individual with dysarthria and how speech deviates from a normative range. A complementary approach is to consider the features and consequences of dysarthric speech as…

  20. Ethnicity Knowledge and Attitudes toward Acquired Immune Deficiency Syndrome.

    Science.gov (United States)

    Goh, David S.

    This study examined the effects of race/ethnicity and degree of acculturation on knowledge and attitudes about human immunodeficiency virus/Acquired Immune Deficiency Syndrome (HIV/AIDS). Subjects were 274 college students from 5 racial/ethnic groups (Whites, Blacks, Hispanics, Asian Americans, U.S. born, having an Asian origin with families that…

  1. Spoken Persuasive Discourse Abilities of Adolescents with Acquired Brain Injury

    Science.gov (United States)

    Moran, Catherine; Kirk, Cecilia; Powell, Emma

    2012-01-01

    Purpose: The aim of this study was to examine the performance of adolescents with acquired brain injury (ABI) during a spoken persuasive discourse task. Persuasive discourse is frequently used in social and academic settings and is of importance in the study of adolescent language. Method: Participants included 8 adolescents with ABI and 8 peers…

  2. Hospital acquired diarrhea in a burn center of Tehran

    Directory of Open Access Journals (Sweden)

    Faranak Alinejad

    2016-01-01

    Full Text Available Background and Objectives: Incidence of hospital-acquired diarrhea has increased rapidly and burn patients are at high risk of getting it. Infection with C. difficile is the most common cause of antibiotic associated diarrhea. The aim of this study was to determine the baseline characteristics and clinical presentation of hospital-acquired diarrhea and compare C. difficile and non-C. difficile diarrhea in burn patients treated at a burn center.Materials and Methods: During a 1-year study all patients with hospital-acquired diarrhea at Motahari Burn Hospital, Teh- ran, Iran enrolled in this study. We compared patients with a stool sample positive for C. difficile toxin or tracing the antigen in patients who were negative for detection of toxin in their stool sample specimens.Results: Diarrhea developed in 37 patients out of 3200 admitted patients with a mean burn size of 34.8 ±20.1%. Among them, 8 patients had a positive result for C. difficile. The mean time between antibiotic therapy and occurrence of diarrhea was 9.5 ± 6.2 days. Nine (23.7% patients died in the 7.8± 4.2 days, mostly due to co-morbidities. The mean duration of di- arrhea was 3.6 ± 2 days. Twenty two (57.9% patients were treated with oral metronidazol and eleven (28.9% patients were treated with combination of metronidazole and vancomycin, higher rate of combination therapy was seen in Clostridium difficile CDI.Conclusion: Overall, the prevalence of hospital-acquired diarrhea was 120/10,000  and 21% of them caused by infection with C. difficile. Presence of peripheral leukocytosis and colitis were the alarm sign for diagnosis of C. difficile infection. Keywords: Hospital-acquired diarrhea (HAD, Burn, Clostridium difficile infection (CDI

  3. Wetland Mapping with Quad-Pol Data Acquired during Tandem-X Science Phase

    Science.gov (United States)

    Mleczko, M.; Mroz, M.; Fitrzyk, M.

    2016-06-01

    The aim of this study was to exploit fully polarimetric SAR data acquired during TanDEM-X - Science Phase (2014/2015) over herbaceous wetlands of the Biebrza National Park (BbNP) in North-Eastern Poland for mapping seasonally flooded grasslands and permanent natural vegetation associations. The main goal of this work was to estimate the advantage of fully polarimetric radar images (QuadPol) versus alternative polarization (AltPol) modes. The methodology consisted in processing of several data subsets through polarimetric decompositions of complex quad-pol datasets, classification of multitemporal backscattering images, complementing backscattering images with Shannon Entropy, exploitation of interferometric coherence from tandem operations. In each case the multidimensional stack of images has been classified using ISODATA unsupervised clustering algorithm. With 6 QUAD-POL TSX/TDX acquisitions it was possible to distinguish correctly 5 thematic classes related to their water regime: permanent water bodies, temporarily flooded areas, wet grasslands, dry grasslands and common reed. This last category was possible to distinguish from deciduous forest only with Yamaguchi 4 component decomposition. The interferometric coherence calculated for tandem pairs turned out not so efficient as expected for this wetland mapping.

  4. ImageNet

    International Nuclear Information System (INIS)

    This paper reports on the development of a system for the acquisition, display, analysis, and storage of radiographic images that would be powerful, simple, and cheap enough to be used by the practicing radiologist. Digital images are electronically acquired directly from clinical imaging systems in several seconds without interrupting imaging activity and are displayed on a workstation with the same clarity, resolution, and gray scale as at the imaging system console. With use of a Hyper-Card shell, images are automatically stored in a database as part of a reference and teaching file and can be instantly recalled by a variety of parameters, including the disease entity, an organ of interest, the patient's name, or any term in the diagnostic impression

  5. Optimization of Synthetic Aperture Image Quality

    OpenAIRE

    Moshavegh, Ramin; Jensen, Jonas; Villagómez Hoyos, Carlos Armando; Stuart, Matthias Bo; Hemmsen, Martin Christian; Jensen, Jørgen Arendt

    2016-01-01

    Synthetic Aperture (SA) imaging produces high-quality images and velocity estimates of both slow and fast flow at high frame rates. However, grating lobe artifacts can appear both in transmission and reception. These affect the image quality and the frame rate. Therefore optimization of parameters effecting the image quality of SA is of great importance, and this paper proposes an advanced procedure for optimizing the parameters essential for acquiring an optimal image quality, while generati...

  6. Reconstruction of Undersampled Atomic Force Microscopy Images

    DEFF Research Database (Denmark)

    Jensen, Tobias Lindstrøm; Arildsen, Thomas; Østergaard, Jan;

    2013-01-01

    Atomic force microscopy (AFM) is one of the most advanced tools for high-resolution imaging and manipulation of nanoscale matter. Unfortunately, standard AFM imaging requires a timescale on the order of seconds to minutes to acquire an image which makes it complicated to observe dynamic processes...

  7. Mars Image Collection Mosaic Builder

    Science.gov (United States)

    Plesea, Lucian; Hare, Trent

    2008-01-01

    A computer program assembles images from the Mars Global Surveyor (MGS) Mars Observer Camera Narrow Angle (MOCNA) collection to generate a uniform-high-resolution, georeferenced, uncontrolled mosaic image of the Martian surface. At the time of reporting the information for this article, the mosaic covered 7 percent of the Martian surface and contained data from more than 50,000 source images acquired under various light conditions at various resolutions.

  8. Cerebral imaging and dementia

    Energy Technology Data Exchange (ETDEWEB)

    Rascol, A.; Celsis, P.; Berry, I.

    1989-02-01

    Modern imaging techniques undoubtedly are of value when applied to the study of dementia. This value, however, varies with the technique utilized, and one must distinguish between acquired and potential knowledge. Morphological imaging with computerized tomography or magnetic resonance detects or confirms certain causes of dementia (tumours, lacunae, hydrocephalus with normal CSF pressure), but it is still not sensitive and specific enough to be very useful in primary dementias. Functional imaging (essentially with emission tomography) has already provided interesting data in the study of degenerative dementia (correlations with neuropsychology, subtyping), but what is most promising is its possibilities in the physiopathological approach of the disease.

  9. Cerebral imaging and dementia

    International Nuclear Information System (INIS)

    Modern imaging techniques undoubtedly are of value when applied to the study of dementia. This value, however, varies with the technique utilized, and one must distinguish between acquired and potential knowledge. Morphological imaging with computerized tomography or magnetic resonance detects or confirms certain causes of dementia (tumours, lacunae, hydrocephalus with normal CSF pressure), but it is still not sensitive and specific enough to be very useful in primary dementias. Functional imaging (essentially with emission tomography) has already provided interesting data in the study of degenerative dementia (correlations with neuropsychology, subtyping), but what is most promising is its possibilities in the physiopathological approach of the disease

  10. Label-acquired magnetorotation for biosensing: An asynchronous rotation assay

    Energy Technology Data Exchange (ETDEWEB)

    Hecht, Ariel, E-mail: hecht@umich.ed [University of Michigan, Department of Biomedical Engineering, 2200 Bonisteel, Ann Arbor, MI 48109-2099 (United States); University of Michigan, Department of Chemistry, 930 North University, Ann Arbor, MI 48109-1055 (United States); Kinnunen, Paivo, E-mail: pkkinn@umich.ed [University of Michigan, Department of Chemistry, 930 North University, Ann Arbor, MI 48109-1055 (United States); University of Michigan, Applied Physics Program, 2477 Randall Laboratory, Ann Arbor, MI 48109-1120 (United States); McNaughton, Brandon, E-mail: bmcnaugh@umich.ed [University of Michigan, Department of Biomedical Engineering, 2200 Bonisteel, Ann Arbor, MI 48109-2099 (United States); University of Michigan, Department of Chemistry, 930 North University, Ann Arbor, MI 48109-1055 (United States); University of Michigan, Applied Physics Program, 2477 Randall Laboratory, Ann Arbor, MI 48109-1120 (United States); Kopelman, Raoul, E-mail: kopelman@umich.ed [University of Michigan, Department of Biomedical Engineering, 2200 Bonisteel, Ann Arbor, MI 48109-2099 (United States); University of Michigan, Department of Chemistry, 930 North University, Ann Arbor, MI 48109-1055 (United States); University of Michigan, Applied Physics Program, 2477 Randall Laboratory, Ann Arbor, MI 48109-1120 (United States)

    2011-02-15

    This paper presents a novel application of magnetic particles for biosensing, called label-acquired magnetorotation (LAM). This method is based on a combination of the traditional sandwich assay format with the asynchronous magnetic bead rotation (AMBR) method. In label-acquired magnetorotation, an analyte facilitates the binding of a magnetic label bead to a nonmagnetic solid phase sphere, forming a sandwich complex. The sandwich complex is then placed in a rotating magnetic field, where the rotational frequency of the sandwich complex is a function of the amount of analyte attached to the surface of the sphere. Here, we use streptavidin-coated beads and biotin-coated particles as analyte mimics, to be replaced by proteins and other biological targets in future work. We show this sensing method to have a dynamic range of two orders of magnitude.

  11. Improving survival among Brazilian children with perinatally-acquired AIDS

    Directory of Open Access Journals (Sweden)

    Luiza Harunari Matida

    2004-12-01

    Full Text Available Brazil was the first developing country to provide free, universal access to antiretroviral treatment for AIDS patients. The Brazilian experience thus provides the first evidence regarding the impact of such treatment on the survival of perinatally acquired AIDS cases in the developing world. MATERIAL AND METHODS: This retrospective cohort study used medical record reviews to examine characteristics and trends in the survival of a representative sample of 914 perinatally acquired AIDS cases in 10 Brazilian cities diagnosed between 1983 and 1998. RESULTS: Survival time increased steadily and substantially. Whereas half of the children died within 20 months of diagnosis at the beginning of the epidemic, 75% of children diagnosed in 1997 and 1998 were still alive after four years of follow-up. CONCLUSIONS: Advances in management and treatment have made a great difference in the survival of Brazilian children with AIDS. These results argue strongly for making such treatment available to children in the entire developing world.

  12. Acquired vulvar lymphangioma circumscriptum after cervical cancer treatment: Case report.

    Science.gov (United States)

    Valente, Kari; Montgomery, Kathleen; Schultenover, Stephen; Desouki, Mohamed Mokhtar

    2016-04-01

    Vulvar lymphangioma circumscriptum (LC) is a rare entity which may present as a painful, warty lesion. In contrast to the congenital form, which occurs in children, the acquired form arises in older adults and may be associated with infection, Crohn's disease, or prior pelvic/regional surgery. We present a case of acquired LC of the vulva in a 55-year-old woman who presented with a 3-4 year history of vulvar pain following chemotherapy, radiation, and brachytherapy for cervical cancer. Vulvar shave biopsies followed by excision revealed a thickened dermis with epidermal hyperkeratosis, parakeratosis, elongated rete ridges and dilated lymphatic channels containing eosinophilic material and scattered thrombi. The differential diagnosis for this unusual lesion includes more common conditions such as condyloma acuminatum, fungating squamous cell carcinoma and molluscum contagiosum. It is important to recognize the clinical presentation as well as the distinct histological appearance of this rare benign entity. PMID:27331134

  13. Acquired immunodeficiency syndrome associated with blood-product transfusions

    Energy Technology Data Exchange (ETDEWEB)

    Jett, J.R.; Kuritsky, J.N.; Katzmann, J.A.; Homburger, H.A.

    1983-11-01

    A 53-year-old white man had fever, malaise, and dyspnea on exertion. His chest roentgenogram was normal, but pulmonary function tests showed impaired diffusion capacity and a gallium scan showed marked uptake in the lungs. Results of an open-lung biopsy documented Pneumocystis carinii pneumonia. Immunologic test results were consistent with the acquired immunodeficiency syndrome. The patient denied having homosexual contact or using intravenous drugs. Twenty-nine months before the diagnosis of pneumocystis pneumonia was made, the patient had had 16 transfusions of whole blood, platelets, and fresh-frozen plasma during coronary artery bypass surgery at another medical center. This patient is not a member of any currently recognized high-risk group and is believed to have contracted the acquired immunodeficiency syndrome from blood and blood-product transfusions.

  14. Acquiring Word-Meaning Mappings for Natural Language Interfaces

    CERN Document Server

    Thompson, C

    2011-01-01

    This paper focuses on a system, WOLFIE (WOrd Learning From Interpreted Examples), that acquires a semantic lexicon from a corpus of sentences paired with semantic representations. The lexicon learned consists of phrases paired with meaning representations. WOLFIE is part of an integrated system that learns to transform sentences into representations such as logical database queries. Experimental results are presented demonstrating WOLFIE's ability to learn useful lexicons for a database interface in four different natural languages. The usefulness of the lexicons learned by WOLFIE are compared to those acquired by a similar system, with results favorable to WOLFIE. A second set of experiments demonstrates WOLFIE's ability to scale to larger and more difficult, albeit artificially generated, corpora. In natural language acquisition, it is difficult to gather the annotated data needed for supervised learning; however, unannotated data is fairly plentiful. Active learning methods attempt to select for annotation...

  15. Acquired immunodeficiency syndrome associated with blood-product transfusions

    International Nuclear Information System (INIS)

    A 53-year-old white man had fever, malaise, and dyspnea on exertion. His chest roentgenogram was normal, but pulmonary function tests showed impaired diffusion capacity and a gallium scan showed marked uptake in the lungs. Results of an open-lung biopsy documented Pneumocystis carinii pneumonia. Immunologic test results were consistent with the acquired immunodeficiency syndrome. The patient denied having homosexual contact or using intravenous drugs. Twenty-nine months before the diagnosis of pneumocystis pneumonia was made, the patient had had 16 transfusions of whole blood, platelets, and fresh-frozen plasma during coronary artery bypass surgery at another medical center. This patient is not a member of any currently recognized high-risk group and is believed to have contracted the acquired immunodeficiency syndrome from blood and blood-product transfusions

  16. Тhe features of severe community acquired pneumonia

    Directory of Open Access Journals (Sweden)

    Avramenko I.V.

    2015-06-01

    Full Text Available Based on data from a prospective analysis for the year of observation, the article presents information about the features of severe community acquired pneumonia in patients who were hospitalized at the department of pulmonology (or therapy, as well as department of the intensive care from three teaching hospitals in Dnepropetrovsk, namely "Dnipropetrovsk City Hospital №6», "Dnipropetrovsk City Hospital №2», "Dnipropetrovsk City Hospital №16», which are the clinical ones of "Dnepropetrovsk Medical Academy of the Ministry of Health Ukraine". Dependence of the severity of the condition shown on duration of illness before admission, features of season character of disease. The effect of breathing exercises on the course of the disease. The results can be the basis for a more personal approach to the development of diagnostic and therapeutic programs for patients with severe community-acquired pneumonia.

  17. Community-acquired Acinetobacter baumannii: clinical characteristics, epidemiology and pathogenesis.

    Science.gov (United States)

    Dexter, Carina; Murray, Gerald L; Paulsen, Ian T; Peleg, Anton Y

    2015-05-01

    Community-acquired Acinetobacter baumannii (CA-Ab) is a rare but serious cause of community-acquired pneumonia in tropical regions of the world. CA-Ab infections predominantly affect individuals with risk factors, which include excess alcohol consumption, diabetes mellitus, smoking and chronic lung disease. CA-Ab pneumonia presents as a surprisingly fulminant course and is characterized by a rapid onset of fever, severe respiratory symptoms and multi-organ dysfunction, with a mortality rate reported as high as 64%. It is unclear whether the distinct clinical syndrome caused by CA-Ab is because of host predisposing factors or unique bacterial characteristics, or a combination of both. Deepening our understanding of the drivers of overwhelming CA-Ab infection will provide important insights into preventative and therapeutic strategies. PMID:25850806

  18. Microsoft Acquired Nokia in Unipolar Operating System Market

    Directory of Open Access Journals (Sweden)

    Netra Pal Singh

    2014-09-01

    Full Text Available The recent big tickets include Microsoft acquiring part of Nokia for US$ 7.2 billion, Verizon buy 45% stake in Vodafone for US$130 billion, Google acquiring Motorola for 12.5 billion. These buyouts are analyzed and commented by experts of the industry. This research paper attempted to collate their view in the context of Microsoft and Nokia deal on six parameters. These parameters are (i reasons for the downfall of the Nokia market share, (ii general comments of the experts, (iii similarities / dissimilarities of past and business models of the smartphone business, (iv reasons for Microsoft to buy out Nokia, (vi impact of buyout on Microsoft, Nokia, consumers and markets.

  19. Nodes of Ranvier and Paranodes in Chronic Acquired Neuropathies

    OpenAIRE

    Carmen Cifuentes-Diaz; Odile Dubourg; Theano Irinopoulou; Marc Vigny; Sylvie Lachkar; Laurence Decker; Patrick Charnay; Natalia Denisenko; Thierry Maisonobe; Jean-Marc Léger; Karine Viala; Jean-Jacques Hauw; Jean-Antoine Girault

    2011-01-01

    Chronic acquired neuropathies of unknown origin are classified as chronic inflammatory demyelinating polyneuropathies (CIDP) and chronic idiopathic axonal polyneuropathies (CIAP). The diagnosis can be very difficult, although it has important therapeutic implications since CIDP can be improved by immunomodulating treatment. The aim of this study was to examine the possible abnormalities of nodal and paranodal regions in these two types of neuropathies. Longitudinal sections of superficial per...

  20. Echocardiographic pattern of acquired heart diseases in Nigeria

    OpenAIRE

    Eyo Effiong Ekpe; Mandu C Ikpe; Idongesit Umoh

    2015-01-01

    Background: Acquired heart diseases (AHDs) are present from childhood to old age, and the frequency of pathology differs according to age and the geographical region of the patients. The aim of this study was to document the echocardiographic patterns of AHDs in our setting. Materials and Methods: Retrospective analysis of echocardiographic diagnosis of AHD was done for age, sex, and echocardiographic pattern. Results: There were 190 diagnoses in the 163 patients with 27 patients having a dou...

  1. CHARACTERIZATION OF HOSPITAL ACQUIRED METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS

    OpenAIRE

    Preethi. B.M; J.Vimalin Hena

    2012-01-01

    Methicillin Resistant Staphylococcus aureus (MRSA) strains have emerged as one of the most important nosocomial pathogens. The MRSA can cause a wide range of diseases, which is associated with its production to large number of extracellular toxins and other virulence factors. The diseases are toxic shock syndrome, scalded skin syndrome and food poisoning. Hospital-acquired MRSA (HA-MRSA) in persons who have had frequent or recent contact with hospitals or healthcare facilities within the prev...

  2. Onychomycosis by Fusarium oxysporum probably acquired in utero

    OpenAIRE

    Carvalho, Vania O; Vicente, Vania A.; Betina Werner; Gomes, Renata R.; Gheniffer Fornari; Herkert, Patricia F.; Cristina O. Rodrigues; Abagge, Kerstin T.; Renata Robl; Camiña, Ricardo H

    2014-01-01

    Fusarium oxysporum has been described as a pathogen causing onychomycosis, its incidence has been increasing in immunocompetent and disseminated infection can occur in immunosuppressed individuals. We describe the first case of congenital onychomycosis in a child caused by Fusarium oxysporum. The infection being acquired in utero was proven by molecular methods with the identification of the fungus both in the nail and placenta, most probably as an ascending contamination/infection in a HIV-p...

  3. Community-Acquired Pneumonia: 2012 History, Mythology, and Science

    OpenAIRE

    Donowitz, Gerald R.

    2013-01-01

    Pneumonia remains one of the major disease entities practicing physicians must manage. It is a leading cause of infection-related morbidity and mortality in all age groups, and a leading cause of death in those older than 65 years of age. Despite its frequency and importance, clinical questions have remained in the therapy of community-acquired pneumonia including when to start antibiotics, when to stop them, who to treat, and what agents to use. Answers to these questions have involved histo...

  4. Acquiring Ecg Signals And Analysing For Different Heart Ailments

    OpenAIRE

    B.Sravanthi; Seshukumar Chegu

    2015-01-01

    This paper describes and focuses on acquiring and identification of cardiac diseases using ECG waveform in LabVIEW software, which would bridge the gap between engineers and medical physicians. This model work collects the waveform of an affected person. The waveform is analyzed for diseases and then a report is sent to the doctor through mail. Initially the waveforms are collected from the person using EKG sensor with the help of surface electrodes and the hardware controlled by ...

  5. Nuclear EGFR Contributes to Acquired Resistance to Cetuximab

    OpenAIRE

    Li, Chunrong; Iida, Mari; Dunn, Emily F.; Ghia, Amol J.; Wheeler, Deric L

    2009-01-01

    Epidermal growth factor receptor (EGFR) is a ubiquitously expressed receptor tyrosine kinase involved in the etiology of several human cancers. Cetuximab is an EGFR blocking-antibody that has been approved for the treatment of patients with cancers of the head and neck (HNSCC) and metastatic colorectal cancer (mCRC). Previous reports have shown that EGFR translocation to the nucleus is associated with cell proliferation. Here we investigated mechanisms of acquired resistance to cetuximab usin...

  6. Cognitive rehabilitation in children with acquired brain injuries

    OpenAIRE

    Hagberg-van't Hooft, Ingrid

    2005-01-01

    Deficits in attention, memory and executive functions are the most common cognitive dysfunctions after acquired brain injuries (ABI) and may have a major negative influence on academic and social adjustment. Neuropsychological measures can assess these dysfunctions and shortcomings in academic and social life, but there is a great need for new efficacious cognitive treatment programmes. The main aims of this thesis were to evaluate the direct and maintained effects of a ...

  7. Early neurovascular uncoupling in the brain during community acquired pneumonia

    OpenAIRE

    Rosengarten, Bernhard; Krekel, Dennis; Kuhnert, Stefan; Schulz, Richard

    2012-01-01

    Introduction Sepsis leads to microcirculatory dysfunction and therefore a disturbed neurovascular coupling in the brain. To investigate if the dysfunction is also present in less severe inflammatory diseases we studied the neurovascular coupling in patients suffering from community acquired pneumonia. Methods Patients were investigated in the acute phase of pneumonia and after recovery. The neurovascular coupling was investigated with a simultaneous electroencephalogram (EEG)-Doppler techniqu...

  8. Risk factors for acquired multidrug-resistant tuberculosis

    OpenAIRE

    Barroso Elizabeth Clara; Mota Rosa Maria Salani; Santos Raimunda Oliveira; Sousa Ana Lúcia Oliveira; Barroso Joana Brasileiro; Rodrigues Jorge Luís Nobre

    2003-01-01

    Multidrug-resistant tuberculosis (MDR-TB) is a severe and feared problem, that is difficult to control and has shown a tendency to increase worldwide. OBJECTIVE: To analyze the risk factors for acquired MDR-TB. CASUISTIC AND METHODS: A retrospective population-based case-control study was conducted. A bacillus was considered multidrug-resistant whenever it was resistant at least to rifampin (RFP) + isoniazid (INH), and a case was considered as sensitive tuberculosis (TB) if it had undergone t...

  9. Clinical features of endemic community-acquired psittacosis

    OpenAIRE

    J.M. Branley; Weston, K M; England, J; Dwyer, D E; Sorrell, T C

    2014-01-01

    Following a large outbreak of community-acquired psittacosis in 2002 in residents of the Blue Mountains, New South Wales, Australia, we reviewed new cases in this area over a 7-year period from 2003 to 2009. Using the 2010 criteria from the Centers for Disease Control National Notifiable Diseases Surveillance System, 85 patients with possible psittacosis were identified, of which 48 were identified as definite or probable infection. Clinical features of these cases are summarized. In addition...

  10. A Belgian traveler who acquired yellow fever in The Gambia

    OpenAIRE

    Colebunders, R; Mariage, J. L.; Coche, J. C.; Pirenne, B; Kempinaire, S.; Hantson, P.; Gompel, A; Niedrig, M; Van Esbroeck, M.; Bailey, R; Drosten, C.; Schmitz, H

    2002-01-01

    A 47-year-old Belgian woman acquired yellow fever during a 1-week vacation in The Gambia; she had never been vaccinated against yellow fever. She died of massive gastrointestinal bleeding 7 days after the onset of the first symptoms. This dramatic case demonstrates that it is important for persons to be vaccinated against yellow fever before they travel to countries where yellow fever is endemic, even if the country, like The Gambia, does not require travelers to be vaccinated.

  11. Intensive Care Unit Acquired Weakness: Under or Overdiagnosed?

    OpenAIRE

    Morgado, S; Moura, S.

    2010-01-01

    Intensive care unit-acquired weakness (ICU-AW) is recognized as an important and common clinical problem, associated with an increased morbidity in critical ill patients. This muscle weakness has been described in a wide range of clinical settings and therefore, has many different terminologies such as “critical illness myopathy – CIM”, “critical illness polyneuropathy - CIP”, “acute quadriplegic myopathy”, among others. Nowadays, these designations are considered somewhat restric...

  12. Improving Acquired Immunodeficiency Syndrome Related Cancer Outcomes through International Collaboration

    Institute of Scientific and Technical Information of China (English)

    Mostafa Nokta

    2011-01-01

    @@ The spectrum of cancers seen in human immunodeficiency virus (HIV)infected individuals is diverse and complex,and reflects an ever-changing HIV epidemic.In parts of the world where combination antiretroviral therapy (cART) is available,HIV-infected patients are living longer and are less likely to die of acquired immunodeficiency syndrome (AIDS)defining malignancies within a year or two of developing AIDS.

  13. Cerebral computed tomography in men with acquired immunodeficiency syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Brun, B.; Boesen, F.; Gerstoft, J.; Nielsen, J.O.; Praestholm, J.

    Cerebral CT scannings were performed in 19 homosexual men with the acquired immunodeficiency syndrome (AIDS). Nearly half of them (9 patients) had cortical atrophy. Three patients with toxoplasmosis had cerebral pathology, in two of them with ring enhancement while the third had an ill-defined nonspecific lesion with slight heterogeneous enhancement without ring formation. Two patients with multifocal leucoencephalopathy and non-Hodgkin's lymphoma, respectively, presented non-enhancing, low attenuating lesions at CT.

  14. Acquire information about neutrino parameters by detecting supernova neutrinos

    OpenAIRE

    Huang, Ming-Yang; Guo, Xin-Heng; Young, Bing-Lin

    2010-01-01

    We consider the supernova shock effects, the Mikheyev-Smirnov-Wolfenstein (MSW) effects, the collective effects, and the Earth matter effects in the detection of type II supernova neutrinos on the Earth. It is found that the event number of supernova neutrinos depends on the neutrino mass hierarchy, the neutrino mixing angle $\\theta_{13}$, and neutrino masses. Therefore, we propose possible methods to identify the mass hierarchy and acquire information about $\\theta_{13}$ and neutrino masses ...

  15. Psychotherapy after acquired brain injury: Is less more?

    Directory of Open Access Journals (Sweden)

    Rudi Coetzer

    2014-02-01

    Full Text Available This paper considers the challenges and dilemmas facing psychotherapists working with neurological patients, and in particular those who work in the context of under-resourced brain injury rehabilitation healthcare systems. Through the subjective process of reflective practice integral to clinical supervision, the author attempts to identify five core aspects of psychotherapy intended to augment post-acute long- term rehabilitation programmes and interventions after acquired brain injury.

  16. Escherichia coli and Community-acquired Gastroenteritis, Melbourne, Australia

    OpenAIRE

    Robins-Browne, Roy M.; Bordun, Anne-Marie; Tauschek, Marija; Bennett-Wood, Vicki R.; Russell, Jacinta; Oppedisano, Frances; Lister, Nicole A.; Bettelheim, Karl A.; Fairley, Christopher K.; Sinclair, Martha I; Hellard, Margaret E

    2004-01-01

    As part of a study to determine the effects of water filtration on the incidence of community-acquired gastroenteritis in Melbourne, Australia, we examined fecal samples from patients with gastroenteritis and asymptomatic persons for diarrheagenic strains of Escherichia coli. Atypical strains of enteropathogenic E. coli (EPEC) were the most frequently identified pathogens of all bacterial, viral, and parasitic agents in patients with gastroenteritis. Moreover, atypical EPEC were more common i...

  17. Tacalcitol in the Treatment of Acquired Perforating Collagenosis

    OpenAIRE

    Escribano-Stablé, J.C.; Doménech, C.; Matarredona, J.; Pascual, J.C.; Jaen, A; Vicente, J.

    2014-01-01

    Acquired perforating collagenosis (APC) is a rare perforating dermatosis characterized by transepidermal collagen elimination. We describe a 65-year-old patient, with long-standing type 2 diabetes mellitus and a 2-year history of itchy hyperkeratotic nodules situated on the back, who was subsequently diagnosed with APC. Treatment included topical corticosteroids and antihistamines, without improvement of the lesions. However, therapy with topical tacalcitol administered for 2 months produced ...

  18. Tacalcitol in the Treatment of Acquired Perforating Collagenosis

    Directory of Open Access Journals (Sweden)

    J.C. Escribano-Stablé

    2014-02-01

    Full Text Available Acquired perforating collagenosis (APC is a rare perforating dermatosis characterized by transepidermal collagen elimination. We describe a 65-year-old patient, with long-standing type 2 diabetes mellitus and a 2-year history of itchy hyperkeratotic nodules situated on the back, who was subsequently diagnosed with APC. Treatment included topical corticosteroids and antihistamines, without improvement of the lesions. However, therapy with topical tacalcitol administered for 2 months produced a significant response leading to complete remission of APC.

  19. TEACHING TO USE IN SCIENCE AND MATHEMATICS PREVIOUSLY ACQUIRED SKILLS

    OpenAIRE

    France, Ilze; Namsone, Dace; Čakāne, Līga; Dzērve, Uldis; Vilciņš, Jānis

    2016-01-01

    Goal of the research is to analyse how students currently succeed in using basic skills acquired in mathematics, in science and real-life contexts, before new reforms in Latvia for the development of students' competence have been started. Only about 20% of students in the national testing for 9th grade were able to do it. The research analysed students’ papers, results, and study aids, as well as teacher performance in lessons.

  20. Acquired immunologic tolerance: with particular reference to transplantation

    OpenAIRE

    Starzl, Thomas E.

    2007-01-01

    The first unequivocally successful bone marrow cell transplantation in humans was recorded in 1968 by the University of Minnesota team of Robert A. Good (Gatti et al. Lancet 2: 1366–1369, 1968). This achievement was a direct extension of mouse models of acquired immunologic tolerance that were established 15 years earlier. In contrast, organ (i.e. kidney) transplantation was accomplished precociously in humans (in 1959) before demonstrating its feasibility in any experimental model and in the...

  1. Acquired pendular nystagmus: its characteristics, localising value and pathophysiology

    OpenAIRE

    Gresty, MA; Ell, LL; Findley, Lj

    1982-01-01

    Investigations were made of 16 patients with acquired pendular nystagmus and a further 32 cases reported in the literature were reviewed. Amongst our own patients two thirds had multiple sclerosis, almost one third a cerebrovascular accident or angioma and two had optic atrophy with squint. The nystagmus took forms which could be monocular or binocular, conjugate or disconjugate and could involve movements about single or multiple axes. Spectral analysis was used to characterise the amplitude...

  2. Acquired Surface Alexia in Spanish: A Case Report

    OpenAIRE

    Ferreres, Aldo R.; Macarena Martinez Cuitiño; Alicia Olmedo

    2005-01-01

    This paper reports a case study of acquired surface alexia in Spanish and discusses the most suitable tests to detect this syndrome in a writing system that is very regular for reading at the segmental and supra-segmental levels. Patient MM has surface alexia characterized by quantitatively good performance in reading words and pseudowords; accurate but slow and syllabic reading of words, nonwords and sentences; good performance in lexical decision tasks including words and nonwords; errors i...

  3. Recipient aging accelerates acquired transthyretin amyloidosis after domino liver transplantation.

    Science.gov (United States)

    Misumi, Yohei; Narita, Yasuko; Oshima, Toshinori; Ueda, Mitsuharu; Yamashita, Taro; Tasaki, Masayoshi; Obayashi, Konen; Isono, Kaori; Inomata, Yukihiro; Ando, Yukio

    2016-05-01

    Domino liver transplantation (DLT) with liver grafts from patients with hereditary transthyretin (TTR) amyloidosis has been performed throughout the world because of a severe liver graft shortage. Reports of acquired systemic TTR amyloidosis in domino liver recipients have been increasing; however, the precise pathogenesis and clinical course of acquired TTR amyloidosis remains unclear. We analyzed the relationship between the occurrence of acquired amyloidosis and clinical features in 22 consecutive domino liver donors with hereditary TTR amyloidosis (10 males and 12 females; mean age at DLT: 37.2 years; TTR mutations: V30M [n = 19], Y114C [n = 1], L55P [n = 1], and S50I [n = 1]) and 22 liver recipients (16 males and 6 females; mean age at DLT, 46.2 years). The mean times from DLT to amyloid first appearance and transplant recipient symptom onset were 8.2 years and 9.9 years, respectively. Kaplan-Meier analysis and quantification of the amyloid deposition revealed aging of recipients correlated with early de novo amyloid deposition. The sex of donors and recipients and the age, disease duration, and disease severity of donors had no significant effect on the latency of de novo amyloid deposition. In conclusion, our results demonstrate that recipient aging is associated with the early onset de novo amyloidosis. Because acquired amyloidosis will likely increase, careful follow-up for early amyloidosis detection and new treatments, including TTR stabilizers and gene-silencing therapies, are required. Liver Transplantation 22 656-664 2016 AASLD. PMID:26600212

  4. Cerebral computed tomography in men with acquired immunodeficiency syndrome

    International Nuclear Information System (INIS)

    Cerebral CT scannings were performed in 19 homosexual men with the acquired immunodeficiency syndrome (AIDS). Nearly half of them (9 patients) had cortical atrophy. Three patients with toxoplasmosis had cerebral pathology, in two of them with ring enhancement while the third had an ill-defined nonspecific lesion with slight heterogeneous enhancement without ring formation. Two patients with multifocal leucoencephalopathy and non-Hodgkin's lymphoma, respectively, presented non-enhancing, low attenuating lesions at CT. (orig.)

  5. Community-Acquired Pneumonia in Children: A Multidisciplinary Consensus Review

    OpenAIRE

    Low, Donald E.; Kellner, James D; Allen, Upton; Boucher, Francois D; Kovesi, Thomas; Riesman, John; Davidson, Ross; Joanne M Langley

    2003-01-01

    Community-acquired pneumonia (CAP) is common among children and may have viral, bacterial or, occasionally, other causes. The etiology is complex, with age-related trends, and differs from that in adult CAP, necessitating different management guidelines. There is an absence of current guidelines for the management of pediatric CAP (PCAP) that take into account changing etiologies, antimicrobial-resistance issues and the use of newly licensed antimicrobials. The present review does not provide...

  6. Acquired Incarcerated Inguinal Hernia: A Review of 13 Horses

    OpenAIRE

    Weaver, A. David

    1987-01-01

    The case records of 13 horses with acquired incarcerated inguinal hernia in January-August 1983, were reviewed. Nine cases were in stallions. The remaining four involved eventration 5-48 hours following castration. Ages ranged from 1-17 years. Horses showed a variable degree of colic. Bowel was felt to pass through the internal inguinal ring on rectal examination in most cases. The physical features of the scrotum varied considerably. Resection of ischemic jejunum and/or ileum was necessary i...

  7. CMS’ Hospital-Acquired Conditions for the Neurohospitalist

    OpenAIRE

    Sand, Heather; Owen, Mary; Amin, Alpesh

    2012-01-01

    In 2008, the Centers for Medicare and Medicaid Services (CMS) implemented a provision that denies Medicare payment for hospital-acquired conditions (HACs). This provision brings attention to the quality of patient care and the financial impact associated with “never-events” occurring during a patient’s hospitalization. Our review of HACs focuses on the 5 which are most pertinent to the neurohospitalist: stages III and IV pressure ulcers, catheter-associated urinary tract infection, vascular c...

  8. Onychomycosis by Fusarium oxysporum probably acquired in utero

    Directory of Open Access Journals (Sweden)

    Vania O. Carvalho

    2014-10-01

    Full Text Available Fusarium oxysporum has been described as a pathogen causing onychomycosis, its incidence has been increasing in immunocompetent and disseminated infection can occur in immunosuppressed individuals. We describe the first case of congenital onychomycosis in a child caused by Fusarium oxysporum. The infection being acquired in utero was proven by molecular methods with the identification of the fungus both in the nail and placenta, most probably as an ascending contamination/infection in a HIV-positive, immunosuppressed mother.

  9. Ocular infection caused by Psychrobacter immobilis acquired in the hospital.

    OpenAIRE

    Gini, G A

    1990-01-01

    The name Psychrobacter immobilis recently has been proposed for a group of chiefly psychrotrophic, aerobic, gram-negative, nonmotile, oxidase-positive coccobacilli commonly found associated with fish, processed meat, and poultry products. This article reports an ocular infection in a 12-day-old newborn who acquired the infection in the hospital, probably because of frequent manipulations in a closed aerated incubator. Also, this report intends to alert microbiologists to opportunistic infecti...

  10. A case report of inhalation anthrax acquired naturally

    OpenAIRE

    Azarkar, Zohreh; Zare Bidaki, Majid

    2016-01-01

    Background Anthrax is a zoonotic occupational disease caused by Bacillus anthracis, a rod-shaped immobile aerobic gram-positive bacteria with spore. Anthrax occurs in humans randomly and with low frequency. Most cases of anthrax are acquired through contact with infected animals or contaminated animal products. This old disease became particularly important since 2001 that the biological spores were exploited in America. Depending on the transmission method of the disease, clinical manifestat...

  11. Arabidopsis MAP kinase 4 negatively regulates systemic acquired resistance

    DEFF Research Database (Denmark)

    Petersen, M.; Brodersen, P.; Naested, H.;

    2000-01-01

    Transposon inactivation of Arabidopsis MAP kinase 4 produced the mpk4 mutant exhibiting constitutive systemic acquired resistance (SAR) including elevated salicylic acid (SA) revels, increased resistance to virulent pathogens, and constitutive pathogenesis-related gene expression shown by Northern...... of NPR1. PDF1.2 and THI2.1 gene induction by jasmonate was blocked in mpk4 expressing NahG, suggesting that MPK4 is required for jasmonic acid-responsive gene expression....

  12. Arabidopsis map kinase 4 negatively regulates systemic acquired resistance

    DEFF Research Database (Denmark)

    Brodersen, P; Johansen, Bo; Petersen, M;

    2000-01-01

    Transposon inactivation of Arabidopsis MAP kinase 4 produced the mpk4 mutant exhibiting constitutive systemic acquired resistance (SAR) including elevated salicylic acid (SA) levels, increased resistance to virulent pathogens, and constitutive pathogenesis-related gene expression shown by Northern...... of NPR1. PDF1.2 and THI2.1 gene induction by jasmonate was blocked in mpk4 expressing NahG, suggesting that MPK4 is required for jasmonic acid-responsive gene expression....

  13. Severe Dermatophytosis and Acquired or Innate Immunodeficiency: A Review

    OpenAIRE

    Claire Rouzaud; Roderick Hay; Olivier Chosidow; Nicolas Dupin; Anne Puel; Olivier Lortholary; Fanny Lanternier

    2015-01-01

    Dermatophytes are keratinophilic fungi responsible for benign and common forms of infection worldwide. However, they can lead to rare and severe diseases in immunocompromised patients. Severe forms include extensive and/or invasive dermatophytosis, i.e., deep dermatophytosis and Majocchi’s granuloma. They are reported in immunocompromised hosts with primary (autosomal recessive CARD9 deficiency) or acquired (solid organ transplantation, autoimmune diseases requiring immunosuppressive treatmen...

  14. Acquiring knowledge: Bloomsbury's foray into the academic and online markets

    OpenAIRE

    Barnsley, Connor Reny

    2012-01-01

    Bloomsbury Publishing Plc has recently expanded into the academic market, acquiring six academic publishing houses since 2006 and creating their own imprint, Bloomsbury Academic. The London-based publishing house had been heavily investing in e-book publications and experimenting with an Open Access model. This report examines how Bloomsbury has successfully invested the revenue generated by the Harry Potter series into new academic and digital business ventures. The firm’s growth and expans...

  15. Acquired Fanconi syndrome in patients with Legionella pneumonia

    OpenAIRE

    Kinoshita-Katahashi, Naoko; Fukasawa, Hirotaka; Ishigaki, Sayaka; Isobe, Shinsuke; Imokawa, Shiro; Fujigaki, Yoshihide; Furuya, Ryuichi

    2013-01-01

    Background Hyponatremia is often observed in patients with Legionella pneumonia. However, other electrolyte abnormalities are uncommon and the mechanism remains to be clarified. Case presentation We experienced two male cases of acquired Fanconi syndrome associated with Legionella pneumonia. The laboratory findings at admission showed hypophosphatemia, hypokalemia, hypouricemia and/or hyponatremia. In addition, they had the generalized dysfunction of the renal proximal tubules presenting decr...

  16. Organization and visualization of medical images in radiotherapy

    CERN Document Server

    Lorang, T

    2001-01-01

    In modern radiotherapy, various imaging equipment is used to acquire views from inside human bodies. Tomographic imaging equipment is acquiring stacks of cross-sectional images, software implementations derive three-dimensional volumes from planar images to allow for visualization of reconstructed cross-sections at any orientation and location and higher-level visualization systems allow for transparent views and surface rendering. Of upcoming interest in radiotherapy is mutual information, the integration of information from multiple imaging equipment res. from the same imaging equipment at different time stamps and varying acquisition parameters. Huge amounts of images are acquired nowadays at radiotherapy centers, requiring organization of images with respect to patient, acquisition and equipment to allow for visualization of images in a comparative and integrative manner. Especially for integration of image information from different equipment, geometrical information is required to allow for registration...

  17. Acquired cancer stem cell phenotypes through Oct4-mediated dedifferentiation

    Science.gov (United States)

    Kumar, Suresh M.; Liu, Shujing; Lu, Hezhe; Zhang, Hongtao; Zhang, Paul J.; Gimotty, Phyllis A.; Guerra, Matthew; Guo, Wei; Xu, Xiaowei

    2012-01-01

    There is enormous interest to target cancer stem cells (CSCs) for clinical treatment because these cells are highly tumorigenic and resistant to chemotherapy. Oct4 is expressed by CSC-like cells in different types of cancer. However, function of Oct4 in tumor cells is unclear. In this study, we showed that expression of Oct4 gene or transmembrane delivery of Oct4 protein promoted dedifferentiation of melanoma cells to CSC-like cells. The dedifferentiated melanoma cells showed significantly decreased expression of melanocytic markers and acquired the ability to form tumor spheroids. They showed markedly increased resistance to chemotherapeutic agents and hypoxic injury. In the subcutaneous xenograft and tail vein injection assays, these cells had significantly increased tumorigenic capacity. The dedifferentiated melanoma cells acquired features associated with CSCs such as multipotent differentiation capacity and expression of melanoma CSC markers such as ABCB5 and CD271. Mechanistically, Oct4 induced dedifferentiation was associated with increased expression of endogenous Oct4, Nanog and Klf4, and global gene expression changes that enriched for transcription factors. RNAi mediated knockdown of Oct4 in dedifferentiated cells led to diminished CSC phenotypes. Oct4 expression in melanoma was regulated by hypoxia and its expression was detected in a subpopulation of melanoma cells in clinical samples. Our data indicate that Oct4 is a positive regulator of tumor dedifferentiation. The results suggest that CSC phenotype is dynamic and may be acquired through dedifferentiation. Oct4 mediated tumor cell dedifferentiation may play an important role during tumor progression. PMID:22286766

  18. Naturally acquired antibodies against Clostridium perfringens epsilon toxin in goats.

    Science.gov (United States)

    Veschi, Josir Laine A; Bruzzone, Octavio A; Losada-Eaton, Daniela M; Dutra, Iveraldo S; Fernandez-Miyakawa, Mariano E

    2008-09-15

    Clostridium perfringens type D-producing epsilon toxin is a common cause of death in sheep and goats worldwide. Although anti-epsilon toxin serum antibodies have been detected in healthy non-vaccinated sheep, the information regarding naturally acquired antibodies in ruminants is scanty. The objective of the present report was to characterize the development of naturally acquired antibodies against C. perfringens epsilon toxin in goats. The levels of anti-epsilon toxin antibodies in blood serum of goat kids from two different herds were examined continuously for 14 months. Goats were not vaccinated against any clostridial disease and received heterologous colostrums from cows that were not vaccinated against any clostridial disease. During the survey one of these flocks suffered an unexpectedly severe C. perfringens type D enterotoxemia outbreak. The results showed that natural acquired antibodies against C. perfringens epsilon toxin can appear as early as 6 weeks in young goats and increase with the age without evidence of clinical disease. The enterotoxemia outbreak was coincident with a significant increase in the level of anti-epsilon toxin antibodies. PMID:18538416

  19. Transanal approach in repairing acquired rectovestibular fistula in females

    Institute of Scientific and Technical Information of China (English)

    Ya-Jun Chen; Ting-Chong Zhang; Jin-Zhe Zhang

    2004-01-01

    AIM: To summarize the operative experience of the transanal approach in acquired rectovestibular fistula repair.METHODS: Ninety-six cases of acquired rectovestibular fistula in young females were analyzed retrospectively. The etiology and operative procedure were discussed. Operative essential points were, the patient was laid in prone frog position, with the knees and hips flexed at 90°; the perineum was elevated; and the anal opening was exposed. Four stay sutures were applied to the margin of the fistular orifice in the anal opening at points 3, 6, 9 and 12 o'clock.A circular incision of mucosa surrounding the stay sutures was made. The fistula was dissected from its anal opening to its vestibular opening. The wound of vestibule was sutured,and the rectoanal wound was then sutured transversely.RESULTS: All the 96 patients recovered uneventfully from operation with a successful rate of 93.75%.CONCLUSION: The transanal approach in the treatment of the acquired rectovestibular fistula is a simple and feasible technique.

  20. Technical Equivalency Documentation for a Newly Acquired Alpha Spectroscopy System

    International Nuclear Information System (INIS)

    The response of a recently acquired Canberra(trademark) Alpha Analyst 'Blue' system (Chamber Number's 173-208) used by the Hazards Control, Radiation Safety Section, WBC/Spectroscopy Team has been studied with respect to an existing Canberra system. The existing Canberra system consists of thirty Alpha Analyst dual chambers Model XXXX comprising a total of sixty detectors (Chambers Number's 101-124 and 137-172). The existing chambers were previously compared to an older system consisting of thirty-six Model 7401 alpha spectrometry chambers (Chamber Number's 1-36) Chambers 101-124 and 137-172 are DOELAP accredited. The older system was previously DOELAP accredited for the routine Alpha Spectroscopy program used in LLNL's in vitro bioassay program. The newly acquired Alpha Analyst system operates on a network with software that controls and performs analysis of the current Alpha Analyst system (Chamber Number's 101-124 and 137-172). This exact same software is used for the current system and the newly acquired system and is DOELAP accredited. This document compares results from the existing Alpha System with the newer Alpha Analyst system

  1. Acquired long QT syndrome: a focus for the general pediatrician.

    Science.gov (United States)

    Marzuillo, Pierluigi; Benettoni, Alessandra; Germani, Claudio; Ferrara, Giovanna; D'Agata, Biancamaria; Barbi, Egidio

    2014-04-01

    Acquired long QT syndrome (LQTS) is a disorder of cardiac repolarization most often due to specific drugs, hypokalemia, or hypomagnesemia that may precipitate torsade de pointes and cause sudden cardiac death. Common presentations of the LQTS are palpitations, presyncope, syncope, cardiac arrest, and seizures. An abnormal 12-lead electrocardiogram obtained while the patient is at rest is the key to diagnosis. The occurrence of drug-induced LQTS is unpredictable in any given individual, but a common observation is that most patients have at least 1 identifiable risk factor in addition to drug exposure. The cornerstone of the management of acquired LQTS includes the identification and discontinuation of any precipitating drug and the correction of metabolic abnormalities, such as hypokalemia or hypomagnesemia. Most of the episodes of torsade de pointes are short-lived and terminate spontaneously. We propose a management protocol that could be useful for the daily practice in the emergency pediatric department to reduce the risk of acquired QT prolongation. PMID:24694881

  2. Azathioprine therapy for acquired myasthenia gravis in five dogs.

    Science.gov (United States)

    Dewey, C W; Coates, J R; Ducoté, J M; Meeks, J C; Fradkin, J M

    1999-01-01

    Five dogs with acquired myasthenia gravis (MG), verified via positive serum acetylcholine (ACh) receptor antibody concentrations, were treated with a drug protocol including azathioprine (AZA). Four of the five dogs were concurrently treated with pyridostigmine. Azathioprine was used as the sole immunosuppressive agent in four dogs. One dog was temporarily treated with a combination of an immunosuppressive dose of prednisone and AZA, then maintained on AZA as the sole immunosuppressive drug. Three patients experienced complete remission of clinical signs within three months of therapy. In the four dogs for which follow-up serum ACh receptor antibody concentrations were available, initial versus final concentrations decreased substantially (81%), coincident with clinical improvement. One dog died suddenly due to a suspected myasthenic crisis before attaining the target dose of AZA. Two of the four surviving dogs were euthanized approximately one and seven years after diagnosis. One of these two dogs was euthanized because of a rib osteosarcoma, and the other dog was euthanized because of paraparesis of undetermined cause. The remaining two dogs were alive and doing well at the time of final follow-up evaluation, approximately six months and one year after diagnosis. The use of AZA as a therapeutic agent for acquired canine MG has not been investigated. The cases presented in this report suggest a potentially important role for AZA in the treatment of acquired MG in dogs. PMID:10493415

  3. Overview of recent studies of community-acquired pneumonia.

    Science.gov (United States)

    Higgins, K; Singer, M; Valappil, T; Nambiar, S; Lin, D; Cox, E

    2008-12-01

    All recent studies of antibacterial drugs for the indication of community-acquired pneumonia submitted to the US Food and Drug Administration have been designed as noninferiority studies. We provide a summary of results of 7 recent clinical studies of oral antibacterial drugs for treatment of community-acquired pneumonia. In these 7 studies, the majority of patients enrolled had Pneumonia Patient Outcomes Research Team scores of I or II. The percentage of randomized subjects with pathogens identified at baseline ranged from 47% to 76%, and the percentage of subjects with Streptoccocus pneumoniae isolated at baseline ranged from approximately 6% to 20%. The primary end point in these studies was clinical cure, assessed 7-21 days after completion of therapy. Clinical cure rates were >80% in the intent-to-treat populations and >90% in the per-protocol populations. We also briefly summarize the results from several recently submitted clinical studies of intravenously administered antibacterial drugs for treatment of community-acquired pneumonia, in which we found similar results. PMID:18986282

  4. X-ray imaging using digital cameras

    Science.gov (United States)

    Winch, Nicola M.; Edgar, Andrew

    2012-03-01

    The possibility of using the combination of a computed radiography (storage phosphor) cassette and a semiprofessional grade digital camera for medical or dental radiography is investigated. We compare the performance of (i) a Canon 5D Mk II single lens reflex camera with f1.4 lens and full-frame CMOS array sensor and (ii) a cooled CCD-based camera with a 1/3 frame sensor and the same lens system. Both systems are tested with 240 x 180 mm cassettes which are based on either powdered europium-doped barium fluoride bromide or needle structure europium-doped cesium bromide. The modulation transfer function for both systems has been determined and falls to a value of 0.2 at around 2 lp/mm, and is limited by light scattering of the emitted light from the storage phosphor rather than the optics or sensor pixelation. The modulation transfer function for the CsBr:Eu2+ plate is bimodal, with a high frequency wing which is attributed to the light-guiding behaviour of the needle structure. The detective quantum efficiency has been determined using a radioisotope source and is comparatively low at 0.017 for the CMOS camera and 0.006 for the CCD camera, attributed to the poor light harvesting by the lens. The primary advantages of the method are portability, robustness, digital imaging and low cost; the limitations are the low detective quantum efficiency and hence signal-to-noise ratio for medical doses, and restricted range of plate sizes. Representative images taken with medical doses are shown and illustrate the potential use for portable basic radiography.

  5. On line portal imaging

    International Nuclear Information System (INIS)

    is finding a common frame of reference for the simulator and portal images, since the location of the radiation field within the pixel matrix may differ for the two images. This problem is compounded by the fact that the commercially available EPIDs have mechanical slop and do not deploy to exactly the same position repeatedly. As a result, a common frame of reference has to be established before the anatomic structures in the images can be registered - generally by registering radiation field edges identified in the simulator and portal images. In addition, distortions in patient geometry or rotations out of the image plane can confound the image registration techniques. Despite the difficulties, many image registration techniques such as interactive techniques, landmark-based techniques, contrast-based techniques, and hybrid techniques have been developed to detect errors in patient positioning. The advantages and disadvantages of these various techniques will be discussed. Clinical use of portal imaging systems has included the use of static localisation and verification images, the use of 'movie' sequences (sequences of images acquired during one irradiation) and the use of 'time-lapse' sequences of images acquired during consecutive treatments, which demonstrate the variability in patient set-up over a full course of therapy. Possibly the most contentious issue is how to best make use of the information provided the portal images. Philosophies have ranged between intervening in every treatment, to intervening only occasionally, or to identifying patients who would benefit from smaller treatment margins and modifying the treatment plan part way through the course of treatment. Conclusions: While great improvements in portal imaging technology have been made, in the future more effort will to be directed towards improving image quality, and integrating and automating the various steps in the image registration process. In addition, other uses for portal imaging

  6. Characterization of SEM speckle pattern marking and imaging distortion by digital image correlation

    International Nuclear Information System (INIS)

    Surface patterning by e-beam lithography and scanning electron microscope (SEM) imaging distortions are studied via digital image correlation. The global distortions from the reference pattern, which has been numerically generated, are first quantified from a digital image correlation procedure between the (virtual) reference pattern and the actual SEM image both in secondary and backscattered electron imaging modes. These distortions result from both patterning and imaging techniques. These two contributions can be separated (without resorting to an external caliper) based on the images of the same patterned surface acquired at different orientations. Patterning distortions are much smaller than those due to imaging on wide field images. (paper)

  7. Community-acquired pneumonia in older patients: does age influence systemic cytokine levels in community-acquired pneumonia?

    LENUS (Irish Health Repository)

    Kelly, Emer

    2009-03-01

    Community-acquired pneumonia (CAP) is a major cause of death in the elderly. The age-related increase in comorbid illnesses plays a part but the effect of aging on the immune response may be equally important. We aimed to evaluate patients with CAP for evidence of a muted response to infection in elderly patients admitted to hospital compared with a younger patient group.

  8. MRI of acquired posterior urethral diverticulum following surgery for anorectal malformations

    Energy Technology Data Exchange (ETDEWEB)

    Podberesky, Daniel J.; Anton, Christopher G. [Cincinnati Children' s Hospital Medical Center, Department of Radiology, Cincinnati, OH (United States); Weaver, Nicholas C. [Cincinnati Children' s Hospital Medical Center, Department of Radiology, Cincinnati, OH (United States); Vanderbilt University, Nashville, TN (United States); Lawal, Taiwo [Cincinnati Children' s Hospital Medical Center, Department of Surgery, Cincinnati, OH (United States); University College Hospital, Department of Surgery, Ibadan (Nigeria); Hamrick, Miller C.; Pena, Alberto; Levitt, Marc A. [Cincinnati Children' s Hospital Medical Center, Department of Surgery, Cincinnati, OH (United States); Alam, Shumyle [Cincinnati Children' s Hospital Medical Center, Department of Urology, Cincinnati, OH (United States)

    2011-09-15

    Posterior urethral diverticulum (PUD) is one of the most common postoperative complications associated with anorectal malformation (ARM) correction. To describe our MRI protocol for evaluating acquired PUD following ARM surgery, and associated imaging findings. Two radiologists retrospectively reviewed 61 pelvic MRI examinations performed for postoperative ARM for PUD identification and characteristics. Associated clinical, operative and cystoscopy reports were also reviewed and compared to MRI. An abnormal retrourethral focus suspicious for PUD was identified at MRI in 13 patients. Ten of these patients underwent subsequent surgery or cystoscopy, and PUD was confirmed in five. All of the confirmed PUD cases appeared as cystic lesions that were at least 1 cm in diameter in two imaging planes. Four of the false-positive cases were punctate retrourethral foci that were visible only on a single MRI plane. One patient had a seminal vesical cyst mimicking a PUD. Pelvic MRI can be a useful tool in the postoperative assessment of suspected PUD associated with ARM. Radiologists should have a high clinical suspicion for a postoperative PUD when a cystic lesion posterior to the bladder/posterior urethra is encountered on two imaging planes in these patients. (orig.)

  9. MRI of acquired posterior urethral diverticulum following surgery for anorectal malformations

    International Nuclear Information System (INIS)

    Posterior urethral diverticulum (PUD) is one of the most common postoperative complications associated with anorectal malformation (ARM) correction. To describe our MRI protocol for evaluating acquired PUD following ARM surgery, and associated imaging findings. Two radiologists retrospectively reviewed 61 pelvic MRI examinations performed for postoperative ARM for PUD identification and characteristics. Associated clinical, operative and cystoscopy reports were also reviewed and compared to MRI. An abnormal retrourethral focus suspicious for PUD was identified at MRI in 13 patients. Ten of these patients underwent subsequent surgery or cystoscopy, and PUD was confirmed in five. All of the confirmed PUD cases appeared as cystic lesions that were at least 1 cm in diameter in two imaging planes. Four of the false-positive cases were punctate retrourethral foci that were visible only on a single MRI plane. One patient had a seminal vesical cyst mimicking a PUD. Pelvic MRI can be a useful tool in the postoperative assessment of suspected PUD associated with ARM. Radiologists should have a high clinical suspicion for a postoperative PUD when a cystic lesion posterior to the bladder/posterior urethra is encountered on two imaging planes in these patients. (orig.)

  10. High-power white LED-based system incorporating a CCD Offner imaging spectrometer for real-time fluorescence qPCR measurements

    International Nuclear Information System (INIS)

    An optical system for qPCR fluorescence measurements which incorporates high-power white LEDs, PMMA plastic lenses and an Offner multichannel (imaging) CCD-based spectrometer has been developed and validated. The optical system can detect twenty reaction vessels in an asynchronous manner and up to seven different fluorescent dyes (7 plex) at 1 nM dye concentrations in each of the reaction vessels. Furthermore, PCR curves obtained using the optical measurement system for a genomic deoxyribonucleic acid (DNA) template containing HEX and Texas Red fluorescent probes (fluorophores) are discussed. The spectral resolution, dynamic range and repeatability of the measurement system are < 15 nm, > 3 decades and < 1% CV, respectively. (paper)

  11. Three-dimensional distribution analysis of platinum, palladium and rhodium in auto catalytic converters using imaging-mode laser-induced breakdown spectrometry

    Science.gov (United States)

    Lucena, Patricia; Laserna, J. Javier

    2001-02-01

    Laser-induced breakdown spectrometry (LIBS) is reported here as an effective technique to describe the volume distribution of platinum, rhodium and palladium in catalytic converters installed in motor vehicles. Using the second harmonic output of a Nd:YAG laser and a CCD-based atomic emission spectrometer, LIBS is used in multielemental, imaging-mode to permit the simultaneous analysis of the several elements present in the converter, including the internal standard. The data are reported with a lateral resolution of 1.75 mm over a fresh catalytic structure which is 128 mm long. The concentrational variability of the platinum group metals (PGMs) varies in the range ˜3-23% relative standard deviation depending on the element, the substrate and the direction investigated. The causes of the dispersion observed are discussed.

  12. Whole mouse cryo-imaging

    Science.gov (United States)

    Wilson, David; Roy, Debashish; Steyer, Grant; Gargesha, Madhusudhana; Stone, Meredith; McKinley, Eliot

    2008-03-01

    The Case cryo-imaging system is a section and image system which allows one to acquire micron-scale, information rich, whole mouse color bright field and molecular fluorescence images of an entire mouse. Cryo-imaging is used in a variety of applications, including mouse and embryo anatomical phenotyping, drug delivery, imaging agents, metastastic cancer, stem cells, and very high resolution vascular imaging, among many. Cryo-imaging fills the gap between whole animal in vivo imaging and histology, allowing one to image a mouse along the continuum from the mouse -> organ -> tissue structure -> cell -> sub-cellular domains. In this overview, we describe the technology and a variety of exciting applications. Enhancements to the system now enable tiled acquisition of high resolution images to cover an entire mouse. High resolution fluorescence imaging, aided by a novel subtraction processing algorithm to remove sub-surface fluorescence, makes it possible to detect fluorescently-labeled single cells. Multi-modality experiments in Magnetic Resonance Imaging and Cryo-imaging of a whole mouse demonstrate superior resolution of cryo-images and efficiency of registration techniques. The 3D results demonstrate the novel true-color volume visualization tools we have developed and the inherent advantage of cryo-imaging in providing unlimited depth of field and spatial resolution. The recent results continue to demonstrate the value cryo-imaging provides in the field of small animal imaging research.

  13. Image reconstruction by NMR Fresnel diffractive imaging technique

    International Nuclear Information System (INIS)

    A new approach to MR angiography, the NMR diffractive imaging technique, has been investigated. The expression for NMR signals obtained in the NMR diffractive imaging technique is similar to the equation for Fresnel diffraction in light waves or sound waves. Therefore, it is possible to reconstruct an image focusing on any plane in the depth direction from data scanned two-dimensionally by changing an imaging parameter in the reconstruction step. To support this imaging technique, a coil system composed of six coils was designed. Experiments were performed using an ultra-low-field MRI scanner to acquire two-dimensional data in the proposed technique. Even though blurred images outside the focus are superimposed on the image in the focal plane, the three-dimensional distribution of the object can be recognized by moving the focal plane in the depth direction. To obtain supplemental information for the object, acquiring images from different angles is helpful for recognizing the spatial distribution of the object more precisely. Although the image obtained contains blurred images outside the focus the proposed imaging technique is expected to be useful in MR fast angiography. (author)

  14. Imaging with coincidence detectors

    International Nuclear Information System (INIS)

    The development of a dual-detector, single photon emission computed tomography (SPECT) system that could be modified to perform coincidence imaging of positron-emitting radiotracers has resulted in a renaissance in the nuclear medicine community. In 1996, ADAC Laboratories introduced their Molecula Coincidence Detection (MCD) system at the Society of Nuclear Medicine Annual General Meeting in Denver. This ushered in a new era in nuclear medicine imaging. The ability of these coincidence systems to image 18FDG promises to make this type of imaging 'just another nuclear medicine procedure', possible within the next decade. This advancement is arguably the biggest news in nuclear medicine since the development of SPECT. In August 1997, Lion's Gate Hospital in North Vancouver acquired the MCD upgrade to their ADAC Vertex camera - the first and only to date in Canada. This article introduces coincidence imaging and describes the experiences of those pioneering the use of this new modality in Canada

  15. Images of Usability

    DEFF Research Database (Denmark)

    Hertzum, Morten

    2010-01-01

    The term usability is ubiquitous in human-computer interaction, so much so that it is commonly used without definition. Rather than one established meaning of usability, there are, however, multiple images of usability. While each image provides a partial view, the partiality remains implicit...... manifold aspects of the use of a system and thereby acquiring a genuine understanding of its usability. The six images differ, for example, in the extent to which they include aspects of the outcome of the process of using a system or merely the process of use, whether they involve collaborative use or...... assume different images of usability and a need for supplementary methods addressing the collaborative and long-term aspects of usability. Moreover, the images call for extending the scope of practical usability work to include the effects achieved by users during their use of systems for real work....

  16. Diffusion tensor imaging of the auditory nerve in patients with acquired single-sided deafness

    DEFF Research Database (Denmark)

    Vos, Sjoerd; Haakma, Wieke; Versnel, Huib;

    2015-01-01

    following cochlear hair cell loss, and the amount of degeneration may considerably differ between the two ears, also in patients with bilateral deafness. A measure that reflects the nerve's condition would help to assess the best of both nerves and decide accordingly which ear should be implanted for...... DTI metrics from the deaf-sided with the healthy-sided nerves in patients showed no significant differences. There was a small but significant reduction in fractional anisotropy in both auditory nerves in patients compared with normal-hearing controls. These results are the first evidence of possible...... changes in the microstructure of the bilateral auditory nerves as a result of single-sided deafness. Our results also indicate that it is too early to assess the degenerative status of the auditory nerve of a subject-specific basis....

  17. Processing of images acquired at the Ondřejov double solar refractor

    Czech Academy of Sciences Publication Activity Database

    Klvaňa, Miroslav; Bumba, Václav; Sobotka, Michal

    Garching : European Southern Observatory, 1994 - (Albrecht, M.; Pasian, F.), s. 179-183 - (ESO Conference and Workshop Proceedings. No.50). [ESO- OAT International Workshop Handling and Archiving Data from Ground-based Telescopes. Trieste (IT), 21.04.1993-23.04.1993

  18. Estimating plant traits of grasslands from UAV-acquired hyperspectral images

    NARCIS (Netherlands)

    Capolupo, Alessandra; Kooistra, Lammert; Berendonk, Clara; Boccia, Lorenzo; Suomalainen, Juha

    2015-01-01

    Grassland ecosystems cover around 40% of the entire Earth's surface. Therefore, it is necessary to guarantee good grassland management at field scale in order to improve its conservation and to achieve optimal growth. This study identified the most appropriate statistical strategy, between partia

  19. Can Colors, Voices, and Images Help Learners Acquire the Grammatical Gender of German Nouns?

    Science.gov (United States)

    Dias de Oliveira Santos, Victor

    2015-01-01

    Knowledge of lexical items is arguably the most essential aspect of being able to communicate in a foreign language (Richards, 2000). Many studies have examined effective strategies for retaining the meaning of foreign words, but studies investigating the effectiveness of different methods for the retention of essential grammatical features of…

  20. Aerial Image over Ouray National Wildlife Refuge, Acquired on August 11, 1953

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This data set is a georeferenced version of an original black and white aerial photograph downloaded from Earth Explorer (USGS; www.earthexplorer.usgs.gov). The...

  1. Aerial Image over Ouray National Wildlife Refuge, Acquired on September 4, 1963 (Frame 88)

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This data set is a georeferenced version of an original black and white aerial photograph downloaded from Earth Explorer (USGS; www.earthexplorer.usgs.gov). The...

  2. Aerial Image over Ouray National Wildlife Refuge, Acquired on September 4, 1963 (Frame 134)

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This data set is a georeferenced version of an original black and white aerial photograph downloaded from Earth Explorer (USGS; www.earthexplorer.usgs.gov). The...

  3. Aerial Image over Ouray National Wildlife Refuge, Acquired on September 4, 1963 (Frame 135)

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This data set is a georeferenced version of an original black and white aerial photograph downloaded from Earth Explorer (USGS; www.earthexplorer.usgs.gov). The...

  4. Aerial Image over Ouray National Wildlife Refuge, Acquired on September 4, 1963 (Frame 121)

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This data set is a georeferenced version of an original black and white aerial photograph downloaded from Earth Explorer (USGS; www.earthexplorer.usgs.gov). The...

  5. Magnetic resonance imaging: early detection of central nervous system involvement in acquired immunodeficiency syndrome (AIDS)

    International Nuclear Information System (INIS)

    Central Nervous System (CNS) involvement, whether primary by the Human Immunodeficiency Virus - HIV - itself, or secondary (toxoplasmosis or lymphoma) is remarkably frequent in AIDS, in 40 to 70% of cases, depending upon the author. In order to study the natural history of this illness, a cohort of 25 asymptomatic seropositive patients have been established. Every 6 months these patients undergo biological and clinical examinations, as well as Magnetic Resonance brain scans. After two examinations at a 6 month's interval, the first results are reported. Out of these 25 cases, 9 present anomalies: One patient with diffuse cerebral atrophy and 8 others with high signal intensity areas on T2 weighted sequences, like those of the Multiple Sclerosis. No relationship could be demonstrated between the existence of these lesions and various criteria such as age, sex, risk factors and T4 cells count. The nature of these lesions is not lear. They certainly indicate early involvement of the CNS after primary infection by the HIV virus. They may either represent scars of the primary infection or early alterations announcing developing encephalopathy

  6. Contribution to the morphology and diagnostics of acquired displacements of the urinary bladder

    International Nuclear Information System (INIS)

    Acquired displacements of the urinary bladder refer to intrapelvic pathological anatomy. These alterations of the bladder are predominantly detected via an initial radiologic study with intravenous urography or suprapubic pelvic ultrasonography. According to their clinical incidence displacements of the bladder can occur in: 1. Pelvic space-occupying lesions, 2. Displacements in musculofascial defects of supporting structures as well as in extirpation cavities of the small pelvis, 3. Extrapelvic space-occupying lesions. Herniation, prolapse and descensus of the bladder can be accurately diagnosed by correct examination via intravenous urography. The diagnostics of pelvic and extrapelvic pathogenetic causes require the complex application of all methods of diagnostic imaging, the value of which is determined by clinical diagnosis and by the choice of an appropriate therapy. (orig.)

  7. Rapidly progressed acquired immunodeficiency syndrome dementia complex as an initial manifestation.

    Science.gov (United States)

    Takeuchi, Makoto; Nobukuni, Keigo; Takata, Hiroshi; Kawata, Noriko; Hayashibara, Noriko; Ishizu, Hideki; Takahashi, Kiyoshi

    2005-07-01

    We report a patient with acquired immunodeficiency syndrome dementia complex (ADC) that presented human immunodeficiency virus infection as an initial manifestation. A 34-year-old man developed disturbance of consciousness and severe abulia over 3 months. The CD4 lymphocyte count was 7.9/microl, while human immunodeficiency virus RNA in blood amounted to 4.2 x 10(4) copies/ml. T2-weighted magnetic resonance imaging showed diffusely high signal intensity in the deep white matter of both cerebral hemispheres. On the 20th hospital day, the patient died of sepsis caused by methicillin-resistant Staphylococcus aureus. Autopsy findings in the brain included increased glial cells and multinucleated giant cells in cerebral white matter and subcortical gray matter. These features were compatible with ADC. PMID:16093602

  8. Toxoplasmosis of spinal cord in acquired immunodeficiency syndrome patient presenting as paraparesis: A rare entity

    Directory of Open Access Journals (Sweden)

    Sachin R Agrawal

    2014-01-01

    Full Text Available Although brain has been the most common site for toxoplasma infection in acquired immunodeficiency syndrome patients, involvement of spinal cord by toxoplasma has been rarely found. Spinal cord toxoplasmosis can present as acute onset weakness in both lower limbs associated with sensory and bladder dysfunction. A presumptive diagnosis can be made in patients with CD4 count <100/mm 3 based on a positive serum Toxoplasma gondii IgG antibodies, no recent prophylaxis against toxoplasmosis, intramedullary ring enhancing lesion in spinal cord supported by similar lesions in brain parenchyma. Institutions of antitoxoplasma treatment in such patients result in prompt clinical response and therefore avoiding the need of unnecessary invasive diagnostic tests. Here, we report a case of toxoplasmic myelitis in immunocompromised patient presenting as myelopathy who showed significant clinical improvement after starting antitoxoplasma treatment. Hence toxoplasmic myelitis should be considered in toxoplasma seropositive immunocompromised patients presenting as myelopathy and imaging studies showing ring enhancing intramedullary lesion.

  9. Parametric analysis of synthetic aperture radar data acquired over truck garden vegetation

    Science.gov (United States)

    Wu, S. T.

    1984-01-01

    An airborne X-band SAR acquired multipolarization and multiflight pass SAR images over a truck garden vegetation area. Based on a variety of land cover and row crop direction variations, the vertical (VV) polarization data contain the highest contrast, while cross polarization contains the least. When the radar flight path is parallel to the row direction, both horizontal (HH) and VV polarization data contain very high return which masks out the specific land cover that forms the row structure. Cross polarization data are not that sensitive to row orientation. The inclusion of like and cross polarization data help delineate special surface features (e.g., row crop against non-row-oriented land cover, very-rough-surface against highly row-oriented surface).

  10. The portal vein in children: radiological review of congenital anomalies and acquired abnormalities

    Energy Technology Data Exchange (ETDEWEB)

    Corness, Jonathan A.G.; McHugh, Kieran; Roebuck, Derek J. [Great Ormond Street Hospital for Children, Department of Radiology, London (United Kingdom); Taylor, Andrew M. [Institute of Child Health, Cardiothoracic Unit, London (United Kingdom)

    2006-02-01

    A variety of portal vein anomalies that occur in children can be identified by US, CT, MRI and portal venography. Although these abnormalities can also occur in adults, there are certain pathological processes and aberrations within the portal system that are specific to children. Knowledge of the embryology and anatomy of the portal vein is of benefit in the understanding of these anomalies. Identifying deviations from normal portal architecture is important in the work-up for surgery such as liver transplantation, and prior to interventional procedures such as stent placement or embolization. The aim of this paper is to summarize the various types of congenital and acquired portal vein abnormalities that occur in children, describe their radiological features and provide images to demonstrate the differences from normal portal venous anatomy. (orig.)

  11. Community acquired urinary tract infection: etiology and bacterial susceptibility

    Directory of Open Access Journals (Sweden)

    Dias Neto José Anastácio

    2003-01-01

    Full Text Available PURPOSE: Urinary tract infections (UTI are one of the most common infectious diseases diagnosed. UTI account for a large proportion of antibacterial drug consumption and have large socio-economic impacts. Since the majority of the treatments begins or is done completely empirically, the knowledge of the organisms, their epidemiological characteristics and their antibacterial susceptibility that may vary with time is mandatory. OBJECTIVE: The aim of this study was to report the prevalence of uropathogens and their antibiotic susceptibility of the community acquired UTI diagnosed in our institution and to provide a national data. METHODS: We analyzed retrospectively the results of urine cultures of 402 patients that had community acquired urinary tract infection in the year of 2003. RESULTS: The mean age of the patients in this study was 45.34 ± 23.56 (SD years. There were 242 (60.2% females and 160 (39.8% males. The most commonly isolated organism was Escherichia coli (58%. Klebsiella sp. (8.4% and Enterococcus sp.(7.9% were reported as the next most common organisms. Of all bacteria isolated from community acquired UTI, only 37% were sensitive to ampicillin, 51% to cefalothin and 52% to trimethoprim/sulfamethoxazole. The highest levels of susceptibility were to imipenem (96%, ceftriaxone (90%, amikacin (90%, gentamicin (88%, levofloxacin (86%, ciprofloxacin (73%, nitrofurantoin (77% and norfloxacin (75%. CONCLUSION: Gram-negative agents are the most common cause of UTI. Fluoroquinolones remains the choice among the orally administered antibiotics, followed by nitrofurantoin, second and third generation cephalosporins. For severe disease that require parenteral antibiotics the choice should be aminoglycosides, third generation cephalosporins, fluoroquinolones or imipenem, which were the most effective.

  12. Gesture Based Educational Software for Children with Acquired Brain Injuries

    Directory of Open Access Journals (Sweden)

    Er. Zainab Pirani

    2010-05-01

    Full Text Available " GESBI” is gesture based audio visual teaching tool designed to help children with acquired brain injuries, providing hours of entertainment in a play-and-learn environment while introducing the foundation skills in basic arithmetic, spelling, reading and solving puzzles. These children communicate with the computer via gestures based on my previous research paper “KONCERN- Hand Gesture Recognition for Physically Impaired” in which gestures are captured by camera and processed without the need of wearing any sensor based gloves etc.

  13. Waddington's widget: Hsp90 and the inheritance of acquired characters.

    Science.gov (United States)

    Ruden, Douglas M; Garfinkel, Mark D; Sollars, Vincent E; Lu, Xiangyi

    2003-10-01

    Conrad Waddington published an influential model for evolution in his 1942 paper, Canalization of Development and Inheritance of Acquired Characters. In this classic, albeit controversial, paper, he proposed that an unknown mechanism exists that conceals phenotypic variation until the organism is stressed. Recent studies have proposed that the highly conserved chaperone Hsp90 could function as a "capacitor," or an "adaptively inducible canalizer," that masks silent phenotypic variation of either genetic or epigenetic origin. This review will discuss evidence for, and arguments against, the role of Hsp90 as a capacitor for morphological evolution, and as a key component of what we call "Waddington's widget." PMID:14986860

  14. Acquired Lymphangioma Circumscriptum Caused Macroglossia: A Case Report

    Directory of Open Access Journals (Sweden)

    Mahmut Sami Metin

    2015-03-01

    Full Text Available Lymphangioma circumscriptum (LC is a hamartomatous vascular malformation of lymphatic channels. The etiology is not fully understood. It is usually congenital. Lesions are characterized as thin-walled and grouped vesicles. Lesions are usually seen on proximal extremities, shoulder, axilla, abdomen and neck. They are rarely seen on genital and oral mucosa. Our case was 20 years old male suffering from growing, pain and burning of tongue for 2 months durations. There was a plaque consisted of grouped vesicles on tongue in dermatological examination. Biopsy was obtained. LC was diagnosed. We decided to report this case since acquired LC on tongue and macroglossi is very rare in literature.

  15. Acquired lymphangiectasis following surgery and radiotherapy of breast cancer

    Directory of Open Access Journals (Sweden)

    Angoori Gnaneshwar Rao

    2015-01-01

    Full Text Available Acquired lymphangiectasia (AL is a significant and rare complication of surgery and radiotherapy. We report lymphangiectasia in a 40-year-old woman who had undergone radical mastectomy and radiotherapy. After 4 years of combined therapy, she developed multiple vesicles and bullae. Skin biopsy confirmed the diagnosis of lymphangiectasia. The case is unique as it is not associated with lymphedema, which is a usual accompaniment of lymphangiectasia following surgery and radiotherapy. AL is usually asymptomatic, but trauma may cause recurrent cellulitis. Treatment modalities include electrodessication, surgical excision, sclerotherapy and carbon dioxide laser ablation.

  16. Integrating New Technical Staff: Implications for Acquiring New Technology

    OpenAIRE

    Lee, Denis M. S.; Allen, Thomas J. (Thomas John), 1931-

    1982-01-01

    Hiring new staff in R&D provides an important opportunity for a firm to acquire new technological knowledge. It also takes a considerable length of time before new R&D staff become fully integrated into the organization. This study compares the communication patterns of new and veteran R&D staff as a function of their work activities. The results suggest that both the benefits and problems in the hiring and integration of new R&D staff is moderated by the type of research, development or tech...

  17. Multinational Exploration of Acquired R&D Activities

    DEFF Research Database (Denmark)

    Gammelgaard, Jens

    2004-01-01

    This paper presents the results of a survey of 54 Danish multinational corporations that haveacquired activities abroad. The role of the acquired R&D units was the focus of the survey,particularly with respect to the schism between basic and applied R&D, and the schismbetween autonomous and netwo...... combination of basic andnetwork-oriented R&D activities when focusing on capability development.Keywords: Acquisition; Research and Development (R&D), Basic R&D, Applied R&D,Autonomy, Network, Capabilities....

  18. [Epidemiology of community-acquired pneumonia in children. Current data].

    Science.gov (United States)

    Marguet, C; Bocquel, N; Mallet, E

    1998-01-01

    Viruses, particularly syncitial respiratory virus, are the main aetiology of community-acquired lower respiratory tract infections in infants, while bacterial agents are more frequently responsible in children older than 3 years. Antimicrobial therapy must take into account the development of reduced susceptibility of penicillin to strains of Streptoccocus pneumoniae and Haemophilus influenzae with beta-lactamase, and high frequency of Mycoplasma pneumoniae and Chlamydia pneumoniae infections. Although the mortality rate has remained low in France, the morbidity appeared to increase in recent years. PMID:10223154

  19. Longitudinal, intermodality registration of quantitative breast PET and MRI data acquired before and during neoadjuvant chemotherapy: Preliminary results

    International Nuclear Information System (INIS)

    Purpose: The authors propose a method whereby serially acquired DCE-MRI, DW-MRI, and FDG-PET breast data sets can be spatially and temporally coregistered to enable the comparison of changes in parameter maps at the voxel level. Methods: First, the authors aligned the PET and MR images at each time point rigidly and nonrigidly. To register the MR images longitudinally, the authors extended a nonrigid registration algorithm by including a tumor volume-preserving constraint in the cost function. After the PET images were aligned to the MR images at each time point, the authors then used the transformation obtained from the longitudinal registration of the MRI volumes to register the PET images longitudinally. The authors tested this approach on ten breast cancer patients by calculating a modified Dice similarity of tumor size between the PET and MR images as well as the bending energy and changes in the tumor volume after the application of the registration algorithm. Results: The median of the modified Dice in the registered PET and DCE-MRI data was 0.92. For the longitudinal registration, the median tumor volume change was −0.03% for the constrained algorithm, compared to −32.16% for the unconstrained registration algorithms (p = 8 × 10−6). The medians of the bending energy were 0.0092 and 0.0001 for the unconstrained and constrained algorithms, respectively (p = 2.84 × 10−7). Conclusions: The results indicate that the proposed method can accurately spatially align DCE-MRI, DW-MRI, and FDG-PET breast images acquired at different time points during therapy while preventing the tumor from being substantially distorted or compressed

  20. Effects of Digitization and JPEG Compression on Land Cover Classification Using Astronaut-Acquired Orbital Photographs

    Science.gov (United States)

    Robinson, Julie A.; Webb, Edward L.; Evangelista, Arlene

    2000-01-01

    Studies that utilize astronaut-acquired orbital photographs for visual or digital classification require high-quality data to ensure accuracy. The majority of images available must be digitized from film and electronically transferred to scientific users. This study examined the effect of scanning spatial resolution (1200, 2400 pixels per inch [21.2 and 10.6 microns/pixel]), scanning density range option (Auto, Full) and compression ratio (non-lossy [TIFF], and lossy JPEG 10:1, 46:1, 83:1) on digital classification results of an orbital photograph from the NASA - Johnson Space Center archive. Qualitative results suggested that 1200 ppi was acceptable for visual interpretive uses for major land cover types. Moreover, Auto scanning density range was superior to Full density range. Quantitative assessment of the processing steps indicated that, while 2400 ppi scanning spatial resolution resulted in more classified polygons as well as a substantially greater proportion of polygons < 0.2 ha, overall agreement between 1200 ppi and 2400 ppi was quite high. JPEG compression up to approximately 46:1 also did not appear to have a major impact on quantitative classification characteristics. We conclude that both 1200 and 2400 ppi scanning resolutions are acceptable options for this level of land cover classification, as well as a compression ratio at or below approximately 46:1. Auto range density should always be used during scanning because it acquires more of the information from the film. The particular combination of scanning spatial resolution and compression level will require a case-by-case decision and will depend upon memory capabilities, analytical objectives and the spatial properties of the objects in the image.

  1. Cardiac Image Registration

    Directory of Open Access Journals (Sweden)

    2008-09-01

    Full Text Available Long procedure time and somewhat suboptimal results hinder the widespread use of catheter ablation of complex arrhythmias such as atrial fibrillation (AF. Due to lack of contrast differentiation between the area of interest and surrounding structures in a moving organ like heart, there is a lack of proper intraprocedural guidance using current imaging techniques for ablation. Cardiac image registration is currently under investigation and is in clinical use for AF ablation. Cardiac image registration, which involves integration of two images in the context of left atrium (LA, is intermodal, with the acquired image and the real-time reference image residing in different image spaces, and involves optimization, where one image space is transformed into the other. Unlike rigid body registration, cardiac image registration is unique and challenging due to cardiac motion during the cardiac cycle and due to respiration. This review addresses the basic principles of the emerging technique of registration and the inherent limitations as they relate to cardiac imaging and registration.

  2. Cardiac Image Registration

    Directory of Open Access Journals (Sweden)

    Jasbir Sra

    2008-09-01

    Full Text Available Long procedure time and somewhat suboptimal results hinder the widespread use of catheter ablation of complex arrhythmias such as atrial fibrillation (AF. Due to lack of contrast differentiation between the area of interest and surrounding structures in a moving organ like heart, there is a lack of proper intraprocedural guidance using current imaging techniques for ablation. Cardiac image registration is currently under investigation and is in clinical use for AF ablation. Cardiac image registration, which involves integration of two images in the context of the left atrium (LA, is intermodal, with the acquired image and the real-time reference image residing in different image spaces, and involves optimization, where one image space is transformed into the other. Unlike rigid body registration, cardiac image registration is unique and challenging due to cardiac motion during the cardiac cycle and due to respiration. This review addresses the basic principles of the emerging technique of registration and the inherent limitations as they relate to cardiac imaging and registration.

  3. SUMMARY OF LONG TERM EXPERIENCE IN ACQUIRED HEART DISEASES SURGERY

    Directory of Open Access Journals (Sweden)

    M. L. Semenovsky

    2014-01-01

    Full Text Available In this article we discuss the results of surgical treatment in patients with different acquired heart diseases. Procedures ranged from valve reconstruction, coronary artery revascularization, surgical repair or graft repair of the thoracic aorta to hybrid surgery in patients with combined acquired heart valve diseases and coronary artery diseases. The implementation of biological grafts for aortic repair in 147 cases was successfully performed with low in-hospital mortality (9.8%. Hybrid procedures in patients older than 70 years allowed reducing hospital mortality rate in 3 times in comparison with the standard surgery: 4% vs. 12%, respectively. We developed and introduced into clinical practice the original protocol for patients with aortal valve disease and low left ventricularejection fraction (mean – 24.3%. Due to this protocol 46 procedures were performed, in-hospital mortality was 4.4%. Cardiac surgery in patients on dialysis is one of the priorities in our practice. Our experience demonstrates that short waiting time of kidney transplantation after heart valve replacement improves long-term outcomes.

  4. Acquiring Ecg Signals And Analysing For Different Heart Ailments

    Directory of Open Access Journals (Sweden)

    B.Sravanthi

    2015-03-01

    Full Text Available This paper describes and focuses on acquiring and identification of cardiac diseases using ECG waveform in LabVIEW software, which would bridge the gap between engineers and medical physicians. This model work collects the waveform of an affected person. The waveform is analyzed for diseases and then a report is sent to the doctor through mail. Initially the waveforms are collected from the person using EKG sensor with the help of surface electrodes and the hardware controlled by MCU C8051, acquires ECG and also Phonocardiogram (PCG synchronously and the waveform is sent to the PC installed with LabVIEW software through DAQ-6211. The waveform in digital format is saved and sent to the loops containing conditions for different diseases. If the waveform parameters coincide with any of the looping statements, particular disease is indicated. Simultaneously the patient PCG report is also collected in a separate database containing all information, which will be sent to the doctor through mail.

  5. Prevalence and bacterial susceptibility of hospital acquired urinary tract infection

    Directory of Open Access Journals (Sweden)

    Dias Neto José Anastácio

    2003-01-01

    Full Text Available PURPOSE: Urinary tract infection is the most common nosocomially acquired infection. It is important to know the etiology and antibiotic susceptibility infectious agents to guide the initial empirical treatment. OBJECTIVE: To determine the prevalence of bacterial strains and their antibiotic susceptibility in nosocomially acquired urinary tract infection in a university hospital between January and June 2003. METHODS: We analyzed the data of 188 patients with positive urine culture (= 10(5 colony-forming units/mL following a period of 48 hours after admission. RESULTS: Half of patients were male. Mean age was 50.26 ± 22.7 (SD, range 3 months to 88 years. Gram-negative bacteria were the agent in approximately 80% of cases. The most common pathogens were E. coli (26%, Klebsiella sp. (15%, P. aeruginosa (15% and Enterococcus sp. (11%. The overall bacteria susceptibility showed that the pathogens were more sensible to imipenem (83%, second or third generation cephalosporin and aminoglycosides; and were highly resistant to ampicillin (27% and cefalothin (30%. It is important to note the low susceptibility to ciprofloxacin (42% and norfloxacin (43%. CONCLUSION: This study suggests that if one can not wait the results of urine culture, the best choices to begin empiric treatment are imipenem, second or third generation cephalosporin and aminoglycosides. Cefalothin and ampicillin are quite ineffective to treat these infections.

  6. Clinical features of endemic community-acquired psittacosis

    Directory of Open Access Journals (Sweden)

    J.M. Branley

    2014-01-01

    Full Text Available Following a large outbreak of community-acquired psittacosis in 2002 in residents of the Blue Mountains, New South Wales, Australia, we reviewed new cases in this area over a 7-year period from 2003 to 2009. Using the 2010 criteria from the Centers for Disease Control National Notifiable Diseases Surveillance System, 85 patients with possible psittacosis were identified, of which 48 were identified as definite or probable infection. Clinical features of these cases are summarized. In addition to Chlamydia-specific serology, specimens, where available, underwent nucleic acid testing for chlamydial DNA using real-time PCR. Chlamydophila psittaci DNA was detected in samples from 23 patients. Four of 18 specimens were culture positive. This is the first description of endemic psittacosis, and is characterized in this location by community-acquired psittacosis resulting from inadvertent exposure to birds. The disease is likely to be under-diagnosed, and may often be mistaken for gastroenteritis or meningitis given the frequency of non-respiratory symptoms, particularly without a history of contact with birds. Clinical characteristics of endemic and outbreak-associated cases were similar. The nature of exposure, risk factors and reasons for the occurrence of outbreaks of psittacosis require further investigation.

  7. Exosomes: The missing link between microchimerism and acquired tolerance?

    Science.gov (United States)

    Burlingham, William J

    2014-01-01

    It has become increasingly clear that the immune system of viviparous mammals is much more in the business of acquiring tolerance to non-self antigens, than it is in rejecting cells that express them (for a recent review, highlighting the role of Treg cells, see ref. (1) ). It is also clear that both self-tolerance, and acquired tolerance to non-self is a dynamic process, with a natural ebb and flow. As has been often said of an effective team defense in sports, tolerance will "bend but does not break." How microchimerism, defined as the presence of extremely rare [1/10(4)-1/10(6)] cells of a genetically different individual, can induce either new immunogenetic pressures that push self-tolerance to the breaking point, or alternatively, provide relief from pre-existing immunogenetic risk, preventing development of autoimmune disease, remains a mystery. Indeed, the inability to directly correlate DNA-level microchimerism detected in blood samples by qPCR, with naturally occurring regulation to minor H and MHC alloantigens expressed by the rare cells themselves, has been frustrating to researchers in this field. (2) [Haynes, W.J. et al, this issue] However, recent developments in the areas of transplantation and reproductive immunology offer clues to how the effects of microchimerism can be amplified, and how a disproportionate immune impact might occur from a very limited cell source. PMID:26679558

  8. Analysis of clinical manifestations of symptomatic acquired jejunoileal diverticular disease

    Institute of Scientific and Technical Information of China (English)

    Chia-Yuan Liu; Wen-Hsiung Chang; Shee-Chan Lin; Cheng-Hsin Chu; Tsang-En Wang; Shou-Chuan Shih

    2005-01-01

    AIM: To analyze systematically our experience over 22 years with symptomatic acquired diverticular disease of the jejunum and ileum, exploring the clinical manifestations and diagnosis of this rare but life-threatening disease.METHODS: The medical records of patients with surgically confirmed symptomatic jejunoileal diverticular disease were retrospectively reviewed. Data collected included demographic data, laboratory results, clinical course (acute or chronic), preoperative diagnosis, and operative findings. Inclusion criteria were as follows: (1) surgical confirmation of jejunoileal diverticular disease and (2)exclusion of congenital diverticula (e.g. Meckel's diverticulum).RESULTS: From January 1982 to July 2004, 28 patients with a total of 29 operations met the study criteria. The male:female ratio was 14:14, and the mean age was 62.6±3.5 years. The most common manifestation was abdominal pain. In nearly half of the patients, the symptoms were chronic. Two patients died after surgery. Only four cases were correctly diagnosed prior to surgery, three by small bowel series.CONCLUSION: Symptomatic acquired small bowel diverticular disease is difficult to diagnose. It should be considered in older patients with unexplained chronic abdominal symptoms. A small bowel series may be helpful in diagnosing this potentially life-threatening disease.

  9. Cosmic ray runs acquired with ATLAS muon stations

    CERN Multimedia

    Cerutti, F.

    Starting in the fall 2005 several cosmic ray runs have been acquired in the ATLAS pit with six muon stations. These were three large outer and three large middle chambers of the feet sector (sector 13) that have been readout in the ATLAS cavern. In the first data taking period the trigger was based on two large scintillators (~300x30 cm2) positioned in sector 13 just below the large chambers. In this first run the precision chambers (the Monitored Drift Tubes) were operated in a close to final configuration. Typical trigger rates with this setup were of the order of 1 Hz. Several data sets of 10k events were acquired with final electronics up to the muon ROD and analysed with ATHENA-based software. These data allowed the first checks of the functionality and efficiency of the MDT stations in the ATLAS pit and the first measurement of the FE electronics noise in the ATLAS environment. A few event were also collected in a combined run with the TILE barrel calorimeter. An event display of a cosmic ray a...

  10. Blissfully unaware: Anosognosia and anosodiaphoria after acquired brain injury.

    Science.gov (United States)

    Gasquoine, Philip Gerard

    2016-01-01

    Historically, anosognosia referred to under-report of striking symptoms of acquired brain injury (e.g., hemiplegia) with debilitating functional consequences and was linked with anosodiaphoria, an emotional reaction of indifference. It was later extended to include under-report of all manner of symptoms of acquired brain injury by the patient compared to clinicians, family members, or functional performance. Anosognosia is related to time since onset of brain injury but not consistently to demographic variables, lesion location (except that it is more common after unilateral right than left hemispheric injury), or specific neuropsychological test scores. This review considers all manifestations of anosognosia as a unitary phenomenon with differing clinical characteristics dictated by variability in linked cognitive impairments. It is concluded that anosognosia has three chief contributing factors: (1) procedural: measurement differences across studies in terms of symptom selection and the designation of a "gold standard" of patient symptomatology; (2) psychological: a tendency towards positive self-evaluation and the avoidance of adverse information, that also occurs in neurologically intact individuals; and (3) neuropathological: an increased likelihood of error recognition failure from disconnections that disrupt feedback between injured brain regions governing specific behaviours (symptoms) and anterior cingulate/insular cortex. Anosodiaphoria is considered as an associated symptom, resulting from the same psychological and neuropathological factors. PMID:25686381

  11. [CAPNETZ. The competence network for community-acquired pneumonia (CAP)].

    Science.gov (United States)

    Suttorp, Norbert; Welte, Tobias; Marre, Reinhard; Stenger, Steffen; Pletz, Mathias; Rupp, Jan; Schütte, Hartwig; Rohde, Gernot

    2016-04-01

    CAPNETZ is a medical competence network for community-acquired pneumonia (CAP), which was funded by the German Ministry for Education and Research. It has accomplished seminal work on pneumonia over the last 15 years. A unique infrastructure was established which has so far allowed us to recruit and analyze more than 11,000 patients. The CAPNETZ cohort is the largest cohort worldwide and the results obtained relate to all relevant aspects of CAP management (epidemiology, risk stratification via biomarkers or clinical scores, pathogen spectrum, pathogen resistance, antibiotic management, prevention and health care research). Results were published in more than 150 journals and informed the preparation and update of the national S3-guideline. CAPNETZ was also the foundation for further networks like the Pneumonia Research Network on Genetic Resistance and Susceptibility for the Evolution of Severe Sepsis) (PROGRESS), the Systems Medicine of Community Acquired Pneumonia Network (CAPSyS) and SFB-TR84 (Sonderforschungsbereich - Transregio 84). The main recipients (Charité Berlin, University Clinic Ulm and the Hannover Medical School) founded the CAPNETZ foundation and transferred all data and materials rights to this foundation. Moreover, the ministry granted the CAPNETZ foundation the status of being eligible to apply for research proposals and receive research funds. Since 2013 the CAPNETZ foundation has been an associated member of the German Center for Lung Research (DZL). Thus, a solid foundation has been set up for CAPNETZ to continue its success story. PMID:26984399

  12. Multiple advanced surgical techniques to treat acquired seminal duct obstruction

    Directory of Open Access Journals (Sweden)

    Hong-Tao Jiang

    2014-12-01

    Full Text Available The aim of this study was to evaluate the outcomes of multiple advanced surgical treatments (i.e. microsurgery, laparoscopic surgery and endoscopic surgery for acquired obstructive azoospermia. We analyzed the surgical outcomes of 51 patients with suspected acquired obstructive azoospermia consecutively who enrolled at our center between January 2009 and May 2013. Modified vasoepididymostomy, laparoscopically assisted vasovasostomy and transurethral incision of the ejaculatory duct with holmium laser were chosen and performed based on the different obstruction sites. The mean postoperative follow-up time was 22 months (range: 9 months to 52 months. Semen analyses were initiated at four postoperative weeks, followed by trimonthly (months 3, 6, 9 and 12 semen analyses, until no sperm was found at 12 months or until pregnancy was achieved. Patency was defined as >10,000 sperm ml−1 of semen. The obstruction sites, postoperative patency and natural pregnancy rate were recorded. Of 51 patients, 47 underwent bilateral or unilateral surgical reconstruction; the other four patients were unable to be treated with surgical reconstruction because of pelvic vas or intratesticular tubules obstruction. The reconstruction rate was 92.2% (47/51, and the patency rate and natural pregnancy rate were 89.4% (42/47 and 38.1% (16/42, respectively. No severe complications were observed. Using multiple advanced surgical techniques, more extensive range of seminal duct obstruction was accessible and correctable; thus, a favorable patency and pregnancy rate can be achieved.

  13. Preliminary images from an adaptive imaging system.

    Science.gov (United States)

    Griffiths, J A; Metaxas, M G; Pani, S; Schulerud, H; Esbrand, C; Royle, G J; Price, B; Rokvic, T; Longo, R; Asimidis, A; Bletsas, E; Cavouras, D; Fant, A; Gasiorek, P; Georgiou, H; Hall, G; Jones, J; Leaver, J; Li, G; Machin, D; Manthos, N; Matheson, J; Noy, M; Ostby, J M; Psomadellis, F; van der Stelt, P F; Theodoridis, S; Triantis, F; Turchetta, R; Venanzi, C; Speller, R D

    2008-06-01

    I-ImaS (Intelligent Imaging Sensors) is a European project aiming to produce real-time adaptive X-ray imaging systems using Monolithic Active Pixel Sensors (MAPS) to create images with maximum diagnostic information within given dose constraints. Initial systems concentrate on mammography and cephalography. In our system, the exposure in each image region is optimised and the beam intensity is a function of tissue thickness and attenuation, and also of local physical and statistical parameters in the image. Using a linear array of detectors, the system will perform on-line analysis of the image during the scan, followed by optimisation of the X-ray intensity to obtain the maximum diagnostic information from the region of interest while minimising exposure of diagnostically less important regions. This paper presents preliminary images obtained with a small area CMOS detector developed for this application. Wedge systems were used to modulate the beam intensity during breast and dental imaging using suitable X-ray spectra. The sensitive imaging area of the sensor is 512 x 32 pixels 32 x 32 microm(2) in size. The sensors' X-ray sensitivity was increased by coupling to a structured CsI(Tl) scintillator. In order to develop the I-ImaS prototype, the on-line data analysis and data acquisition control are based on custom-developed electronics using multiple FPGAs. Images of both breast tissues and jaw samples were acquired and different exposure optimisation algorithms applied. Results are very promising since the average dose has been reduced to around 60% of the dose delivered by conventional imaging systems without decrease in the visibility of details. PMID:18291697

  14. Radiographic imaging of aids

    International Nuclear Information System (INIS)

    The acquired immunodeficiency syndrome (AIDS) has impacted the civilized world like no other disease. This research aimed to discuss some of the main aids-related complications and their detection by radiology tests, specifically central nervous system and musculoskeletal system disorders. The objectives are: to show specific characteristics of various diseases of HIV patient, to analyze the effect of pathology in patients by radiology, to enhance the knowledge of technologists in aids imaging and to improve communication skills between patient and radiology technologists

  15. Radiographic imaging of aids

    CERN Document Server

    Mahmoud, M B

    2002-01-01

    The acquired immunodeficiency syndrome (AIDS) has impacted the civilized world like no other disease. This research aimed to discuss some of the main aids-related complications and their detection by radiology tests, specifically central nervous system and musculoskeletal system disorders. The objectives are: to show specific characteristics of various diseases of HIV patient, to analyze the effect of pathology in patients by radiology, to enhance the knowledge of technologists in aids imaging and to improve communication skills between patient and radiology technologists.

  16. Derivative encoding for parallel magnetic resonance imaging a

    OpenAIRE

    Shen, Jun

    2011-01-01

    Purpose: To introduce a linear shift-invariant relationship between the partial derivatives of k space signals acquired using multichannel receive coils and to demonstrate that k space derivatives can be used for image unwrapping.Methods: Fourier transform of k space derivatives contains information on the spatial origins of aliased pixels; therefore, images can be reconstructed by k space derivatives. Fully sampled phantom and brain images acquired at 3 T using a standard eight channel recei...

  17. A comparison of four methods of presenting the data acquired during a colonic transit study

    International Nuclear Information System (INIS)

    A standardised pancake labelled with 20 MBq of 111In Amberlite-resin was used to study colonic transit in spinal-cord-injured subjects. Four methods of presenting the data were assessed in order to determine the best method of presentation for clinical practice. Method: Sixteen subjects (8 tetraplegics, 8 paraplegics), who had sustained traumatic spinal injury at least 12 months prior to the investigation, were studied. Each subject was given a radiolabelled pancake to eat on a Monday, following an overnight fast. Initial anterior and posterior images were acquired at 3-4 hours post ingestion of the pancake and thereafter 3 times daily for a total of 5 days. The colon was divided into 6 regions of interest (ROI) and the counts in each region, for each time point were noted. The counts in each ROI were used to calculate the geometric centre of colonic activity for each time point. The geometric mean (GM) was also calculated from these counts. The percentage activity in each ROI was calculated using the GM. The percentage activity in each ROI was used to construct parametric images, and time-activity curves comparing transit through the right colon with that of the left colon. Visual assessment was made of the analogue images. The agreement between the various methods of analysing the data, for each subject, was compared. Results: There was no complete agreement between the four methods of assessment. The best agreement occurred between the parametric images and the arrival and clearance of activity in the right and left sides of the colon. Conclusion: Visual assessment is subjective. At least two quantitative methods of analysing the data should be used to assess colonic transit

  18. [Imaging of lumbar stenosis].

    Science.gov (United States)

    Morvan, G

    2002-09-01

    The spinal canal is a type of articulated pipe, with rigid rings articulated by joints. It can be divided into a central part, which contains the dural sac, and lateral parts, which contain the nerve roots. The role of imaging is to detect the presence and characterize the nature, level, and severity of stenotic lesions and their impact on neural elements. Stenoses can be constitutional or acquired and involve the central and/or lateral canal. Constitutional stenoses affect both rigid and soft segments whereas acquired stenoses affect mainly the mobile segments. Signs of constitutional stenoses at conventional radiography, CT and MRI will be described. Acquired stenoses are multi-factorial in etiology and more difficult to evaluate. Intra-spinal soft tissues and dynamic factors, poorly assessed at CT and MRI (static imaging), play a major role in this type of stenoses. Currently, only myelography with dynamic evaluation is able to demonstrate the importance of these factors or degree of dynamic stenosis. The lateral canal is divided in three parts: two mobile segments (disco-articular interval, and intervertebral foramen) on each side of a fixed bony segment (lateral recess). The different types of stenoses involving these segments and best imaging technique to demonstrate their presence are described. PMID:12223974

  19. Failure of levofloxacin treatment in community-acquired pneumococcal pneumonia

    Directory of Open Access Journals (Sweden)

    Grossi Paolo

    2005-11-01

    Full Text Available Abstract Background Streptococcus pneumoniae is the leading cause of community-acquired pneumonia (CAP. High global incidence of macrolide and penicillin resistance has been reported, whereas fluoroquinolone resistance is uncommon. Current guidelines for suspected CAP in patients with co-morbidity factors and recent antibiotic therapy recommend initial empiric therapy using one fluoroquinolone or one macrolide associated to other drugs (amoxicillin, amoxicillin/clavulanate, broad-spectrum cephalosporins. Resistance to fluoroquinolones is determined by efflux mechanisms and/or mutations in the parC and parE genes coding for topoisomerase IV and/or gyrA and gyrB genes coding for DNA gyrase. No clinical cases due to fluoroquinolone-resistant S. pneumoniae strains have been yet reported from Italy. Case presentation A 72-year-old patient with long history of chronic obstructive pulmonary disease and multiple fluoroquinolone treatments for recurrent lower respiratory tract infections developed fever, increased sputum production, and dyspnea. He was treated with oral levofloxacin (500 mg bid. Three days later, because of acute respiratory insufficiency, the patient was hospitalized. Levofloxacin treatment was supplemented with piperacillin/tazobactam. Microbiological tests detected a S. pneumoniae strain intermediate to penicillin (MIC, 1 mg/L and resistant to macrolides (MIC >256 mg/L and fluoroquinolones (MIC >32 mg/L. Point mutations were detected in gyrA (Ser81-Phe, parE (Ile460-Val, and parC gene (Ser79-Phe; Lys137-Asn. Complete clinical response followed treatment with piperacillin/tazobactam. Conclusion This is the first Italian case of community-acquired pneumonia due to a fluoroquinolone-resistant S. pneumoniae isolate where treatment failure of levofloxacin was documented. Molecular analysis showed a group of mutations that have not yet been reported from Italy and has been detected only twice in Europe. Treatment with piperacillin

  20. Turbine Imaging Technology Assessment

    Energy Technology Data Exchange (ETDEWEB)

    Moursund, Russell A.; Carlson, Thomas J.

    2004-12-31

    The goal of this project was to identify and evaluate imaging alternatives for observing the behavior of juvenile fish within an operating Kaplan turbine unit with a focus on methods to quantify fish injury mechanisms inside an operating turbine unit. Imaging methods are particularly needed to observe the approach and interaction of fish with turbine structural elements. This evaluation documents both the opportunities and constraints for observing juvenile fish at specific locations during turbine passage. The information may be used to acquire the scientific knowledge to make structural improvements and create opportunities for industry to modify turbines and improve fish passage conditions.