WorldWideScience

Sample records for ccd-based image acquiring

  1. NIR area array CCD-based singlet oxygen luminescence imaging for photodynamic therapy

    International Nuclear Information System (INIS)

    In this work, a near-infrared CCD-based singlet oxygen luminescence two-dimensional imaging method is proposed to detect singlet oxygen by its 1270nm luminescence. Two-dimensional singlet oxygen images with its near-infrared luminescence during photosensitization could be obtained with a CCD integration time of 1s, without scanning. The data presented shows a linear relationship between the singlet oxygen luminescence intensity and sample concentration. This method provides a detection sensitivity of 0.00189mg/ml (Hematoporphyrin monomethyl Ether dissolved in ethanol) and a spatial resolution better than 100μm. We applied this method in vivo to demonstrate its potential in monitoring photodynamic therapy.

  2. A pnCCD-based, fast direct single electron imaging camera for TEM and STEM

    Science.gov (United States)

    Ryll, H.; Simson, M.; Hartmann, R.; Holl, P.; Huth, M.; Ihle, S.; Kondo, Y.; Kotula, P.; Liebel, A.; Müller-Caspary, K.; Rosenauer, A.; Sagawa, R.; Schmidt, J.; Soltau, H.; Strüder, L.

    2016-04-01

    We report on a new camera that is based on a pnCCD sensor for applications in scanning transmission electron microscopy. Emerging new microscopy techniques demand improved detectors with regards to readout rate, sensitivity and radiation hardness, especially in scanning mode. The pnCCD is a 2D imaging sensor that meets these requirements. Its intrinsic radiation hardness permits direct detection of electrons. The pnCCD is read out at a rate of 1,150 frames per second with an image area of 264 x 264 pixel. In binning or windowing modes, the readout rate is increased almost linearly, for example to 4000 frames per second at 4× binning (264 x 66 pixel). Single electrons with energies from 300 keV down to 5 keV can be distinguished due to the high sensitivity of the detector. Three applications in scanning transmission electron microscopy are highlighted to demonstrate that the pnCCD satisfies experimental requirements, especially fast recording of 2D images. In the first application, 65536 2D diffraction patterns were recorded in 70 s. STEM images corresponding to intensities of various diffraction peaks were reconstructed. For the second application, the microscope was operated in a Lorentz-like mode. Magnetic domains were imaged in an area of 256 x 256 sample points in less than 37 seconds for a total of 65536 images each with 264 x 132 pixels. Due to information provided by the two-dimensional images, not only the amplitude but also the direction of the magnetic field could be determined. In the third application, millisecond images of a semiconductor nanostructure were recorded to determine the lattice strain in the sample. A speed-up in measurement time by a factor of 200 could be achieved compared to a previously used camera system.

  3. Fast neutron fields imaging with a CCD-based luminescent detector

    International Nuclear Information System (INIS)

    The paper considers some questions concerned with the development of an imaging system based on a CCD-detector for visualising fast neutron fields. From those the most important are: development of fast neutron screens, detector resistance to irradiation fields, and feasibility of fast neutron radiography and tomography at various neutron sources

  4. Fast neutron fields imaging with a CCD-based luminescent detector

    CERN Document Server

    Mikerov, V

    1999-01-01

    The paper considers some questions concerned with the development of an imaging system based on a CCD-detector for visualising fast neutron fields. From those the most important are: development of fast neutron screens, detector resistance to irradiation fields, and feasibility of fast neutron radiography and tomography at various neutron sources.

  5. Use of a speckle reduction technique to improve the reconstruction image quality of CCD-based optical computed tomography scanner

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Yuan-Jen [Department of Management Information Systems, Central Taiwan University of Science and Technology, No.666, Buzih Rd., Beitun District, Taichung City, Taiwan (R.O.C.) (China); Institute of Biomedical Engineering and Materials Science, Central Taiwan University of Science and Technology, No.666, Buzih Rd., Beitun District, Taichung City, Taiwan (R.O.C.) (China)

    2015-06-01

    This study proposed a speckle reduction technique (SRT) that employs a rotating diffuser in the parallel beam optical computed tomography (CT). Results showed that the mean and standard deviation of the gray level are 89.79±4.53 and 89.16±2.88 for reconstruction images without SRT and with SRT, respectively. The proposed SRT effectively removed ring artifacts. In addition, two image processing techniques, namely, the mean and Wiener filters, were also used to improve the reconstructed images. The image processing technique alone effectively reduced ring artifacts, but some fluctuations were still observed in the line profiles of the reconstructed images. Results proved that the proposed SRT is a simple method that is easily implemented to improve image quality for parallel beam optical CT. The combination of SRT and image filters was suggested to achieve the best image reconstruction quality through the full removal of ring artifacts. - Highlights: • Speckle reduction technique is effective to remove ring artifacts. • The fluctuation in reconstruction image can be reduced using speckle reduction technique. • The image processing technique can reduce the ring artifacts effectively, but few fluctuations can still be observed in line profiles. • The combination speckle reduction technique and image filters can achieve the best quality of reconstruction image.

  6. A CCD-based fluorescence imaging system for real-time loop-mediated isothermal amplification-based rapid and sensitive detection of waterborne pathogens on microchips.

    Science.gov (United States)

    Ahmad, Farhan; Seyrig, Gregoire; Tourlousse, Dieter M; Stedtfeld, Robert D; Tiedje, James M; Hashsham, Syed A

    2011-10-01

    Rapid, sensitive, and low-cost pathogen diagnostic systems are needed for early disease diagnosis and treatment, especially in resource-limited settings. This study reports a low-cost charge-coupled device (CCD)-based fluorescence imaging system for rapid detection of waterborne pathogens by isothermal gene amplification in disposable microchips. Fluorescence imaging capability of this monochromatic CCD camera is evaluated by optimizing the gain, offset, and exposure time. This imaging system is validated for 12 virulence genes of major waterborne pathogens on cyclic olefin polymer (COP) microchips, using SYTO-82 dye and real time fluorescence loop-mediated isothermal amplification referred here as microRT(f)-LAMP. Signal-to-noise ratio (SNR) and threshold time (Tt) of microRT(f)-LAMP assays are compared with those from a commercial real-time polymerase chain reaction (PCR) instrument. Applying a CCD exposure of 5 s to 10(5) starting DNA copies of microRT(f)-LAMP assays increases the SNR by 8-fold and reduces the Tt by 9.8 min in comparison to a commercial real-time PCR instrument. Additionally, single copy level sensitivity for Campylobacter jejuni 0414 gene is obtained for microRT(f)-LAMP with a Tt of 19 min, which is half the time of the commercial real-time PCR instrument. Due to the control over the exposure time and the wide field imaging capability of CCD, this low-cost fluorescence imaging system has the potential for rapid and parallel detection of pathogenic microorganisms in high throughput microfluidic chips.

  7. Acquired portosystemic collaterals: anatomy and imaging*

    Science.gov (United States)

    Leite, Andréa Farias de Melo; Mota Jr., Américo; Chagas-Neto, Francisco Abaeté; Teixeira, Sara Reis; Elias Junior, Jorge; Muglia, Valdair Francisco

    2016-01-01

    Portosystemic shunts are enlarged vessels that form collateral pathological pathways between the splanchnic circulation and the systemic circulation. Although their causes are multifactorial, portosystemic shunts all have one mechanism in common-increased portal venous pressure, which diverts the blood flow from the gastrointestinal tract to the systemic circulation. Congenital and acquired collateral pathways have both been described in the literature. The aim of this pictorial essay was to discuss the distinct anatomic and imaging features of portosystemic shunts, as well as to provide a robust method of differentiating between acquired portosystemic shunts and similar pathologies, through the use of illustrations and schematic drawings. Imaging of portosystemic shunts provides subclinical markers of increased portal venous pressure. Therefore, radiologists play a crucial role in the identification of portosystemic shunts. Early detection of portosystemic shunts can allow ample time to perform endovascular shunt operations, which can relieve portal hypertension and prevent acute or chronic complications in at-risk patient populations. PMID:27777479

  8. CCD-based optical CT scanning of highly attenuating phantoms

    Energy Technology Data Exchange (ETDEWEB)

    Al-Nowais, Shamsa [Department of Physics, University of Surrey, Guildford (United Kingdom); Doran, Simon J [CRUK Clinical MR Research Group, Institute of Cancer Research, Sutton (United Kingdom)], E-mail: Simon.Doran@icr.ac.uk

    2009-05-01

    The introduction of optical computed tomography (optical-CT) offers economic and easy to use 3-D optical readout for gel dosimeters. However, previous authors have noted some challenges regarding the accuracy of such imaging techniques at high values of optical density. In this paper, we take a closer look at the 'cupping' artefact evident in both light-scattering polymer systems and highly light absorbing phantoms using our CCD-based optical scanner. In addition, a technique is implemented whereby the maximum measurable optical absorbance is extended to correct for any errors that may have occurred in the estimated value of the dark current or ambient light reaching the detector. The results indicate that for absorbance values up to 2.0, the optical scanner results have good accuracy, whereas this is not the case at high absorbance values for reasons yet to be explained.

  9. Visibility of microcalcifications in CCD-based cone beam CT: a preliminary study

    Science.gov (United States)

    Shen, Youtao; Chen, Lingyun; Ge, Shuaiping; Yi, Ying; Han, Tao; Zhong, Yuncheng; Lai, Chao-Jen; Liu, Xinming; Wang, Tianpeng; Shaw, Chris C.

    2009-02-01

    In this work, we investigated the visibility of microcalcifications in CCD-based cone beam CT (CBCT) breast imaging. A paraffin cylinder with a diameter of 135 mm and a thickness of 40 mm was used to simulate a 100% adipose breast. Calcium carbonate grains, ranging from 140-150 to 200-212 μm in size, were used to simulate the microcalcifications. Groups of 25 same size microcalcifications were arranged into 5 × 5 clusters. Each cluster was embedded at the center of a smaller (15 mm diameter) cylindrical paraffin phantom, which were inserted into a hole at the center of the breast phantom. The breast phantom with the simulated microcalcifications was scanned on a bench top experimental CCDbased cone beam CT system at various exposure levels with two CCD cameras: Hamamatsu's C4742-56-12ER and Dalsa 99-66-0000-00. 300 projection images were acquired over 360° and reconstructed with Feldkamp's backprojection algorithm using a ramp filter. The images were reviewed by 6 readers independently. The ratios of visible microcalcifications were recorded and averaged over all readers. These ratios were plotted as the function of measured image signal-to-noise ratio (SNR) for various scans. It was found that 94% visibility was achieved for 200-212 μm calcifications at an SNR of 48.2 while 50% visibility was achieved for 200-212, 180-200, 160-180, 150-160 and 140-150 μm calcifications at an SNR of 25.0, 35.3, 38.2, 42.2 and 64.4, respectively.

  10. Radionuclide brain imaging in acquired immunodeficiency syndrome (AIDS)

    Energy Technology Data Exchange (ETDEWEB)

    Costa, D.C.; Gacinovic, S.; Miller, R.F. [London University College Medical School, Middlesex Hospital, London (United Kingdom)

    1995-09-01

    Infection with the Human Immunodeficiency Virus type 1 (HIV-1) may produce a variety of central nervous system (CNS) symptoms and signs. CNS involvement in patients with the Acquired Immunodeficiency Syndrome (AIDS) includes AIDS dementia complex or HIV-1 associated cognitive/motor complex (widely known as HIV encephalopathy), progressive multifocal leucoencephalopathy (PML), opportunistic infections such as Toxoplasma gondii, TB, Cryptococcus and infiltration by non-Hodgkin`s B cell lymphoma. High resolution structural imaging investigations, either X-ray Computed Tomography (CT scan) or Magnetic Resonance Imaging (MRI) have contributed to the understanding and definition of cerebral damage caused by HIV encephalopathy. Atrophy and mainly high signal scattered white matter abnormalities are commonly seen with MRI. PML produces focal white matter high signal abnormalities due to multiple foci of demyelination. However, using structural imaging techniques there are no reliable parameters to distinguish focal lesions due to opportunistic infection (Toxoplasma gondii abscess) from neoplasm (lymphoma infiltration). It is studied the use of radionuclide brain imaging techniques in the investigation of HIV infected patients. Brain perfusion Single Photon Emission Tomography (SPET), neuroreceptor and Positron Emission Tomography (PET) studies are reviewed. Greater emphasis is put on the potential of some radiopharmaceuticals, considered to be brain tumour markers, to distinguish intracerebral lymphoma infiltration from Toxoplasma infection. SPET with {sup 201}Tl using quantification (tumour to non-tumour radioactivity ratios) appears a very promising technique to identify intracerebral lymphoma.

  11. Radionuclide brain imaging in acquired immunodeficiency syndrome (AIDS)

    International Nuclear Information System (INIS)

    Infection with the Human Immunodeficiency Virus type 1 (HIV-1) may produce a variety of central nervous system (CNS) symptoms and signs. CNS involvement in patients with the Acquired Immunodeficiency Syndrome (AIDS) includes AIDS dementia complex or HIV-1 associated cognitive/motor complex (widely known as HIV encephalopathy), progressive multifocal leucoencephalopathy (PML), opportunistic infections such as Toxoplasma gondii, TB, Cryptococcus and infiltration by non-Hodgkin's B cell lymphoma. High resolution structural imaging investigations, either X-ray Computed Tomography (CT scan) or Magnetic Resonance Imaging (MRI) have contributed to the understanding and definition of cerebral damage caused by HIV encephalopathy. Atrophy and mainly high signal scattered white matter abnormalities are commonly seen with MRI. PML produces focal white matter high signal abnormalities due to multiple foci of demyelination. However, using structural imaging techniques there are no reliable parameters to distinguish focal lesions due to opportunistic infection (Toxoplasma gondii abscess) from neoplasm (lymphoma infiltration). It is studied the use of radionuclide brain imaging techniques in the investigation of HIV infected patients. Brain perfusion Single Photon Emission Tomography (SPET), neuroreceptor and Positron Emission Tomography (PET) studies are reviewed. Greater emphasis is put on the potential of some radiopharmaceuticals, considered to be brain tumour markers, to distinguish intracerebral lymphoma infiltration from Toxoplasma infection. SPET with 201Tl using quantification (tumour to non-tumour radioactivity ratios) appears a very promising technique to identify intracerebral lymphoma

  12. Self-acquired patient images: the promises and the pitfalls.

    Science.gov (United States)

    Damanpour, Shadi; Srivastava, Divya; Nijhawan, Rajiv I

    2016-03-01

    Self-acquired patient images, also known as selfies, are increasingly utilized in the practice of dermatology; however, research on their utility is somewhat limited. While the implementation of selfies has yet to be universally accepted, their role in triage appears to be especially useful. The potential for reducing office wait times, expediting referrals, and providing dermatologic services to patients with limited access to care is promising. In addition, as technology advances, the number of smartphone applications related to dermatology that are available to the general public has risen exponentially. With appropriate standardization, regulation, and confidentiality measures, these tools can be feasible adjuncts in clinical practice, dermatologic surgery, and teledermatology. Selfies likely will have a large role in dermatologic practice and delivery in the future.

  13. Self-acquired patient images: the promises and the pitfalls.

    Science.gov (United States)

    Damanpour, Shadi; Srivastava, Divya; Nijhawan, Rajiv I

    2016-03-01

    Self-acquired patient images, also known as selfies, are increasingly utilized in the practice of dermatology; however, research on their utility is somewhat limited. While the implementation of selfies has yet to be universally accepted, their role in triage appears to be especially useful. The potential for reducing office wait times, expediting referrals, and providing dermatologic services to patients with limited access to care is promising. In addition, as technology advances, the number of smartphone applications related to dermatology that are available to the general public has risen exponentially. With appropriate standardization, regulation, and confidentiality measures, these tools can be feasible adjuncts in clinical practice, dermatologic surgery, and teledermatology. Selfies likely will have a large role in dermatologic practice and delivery in the future. PMID:26963112

  14. An image-guided tool to prevent hospital acquired infections

    Science.gov (United States)

    Nagy, Melinda; Szilágyi, László; Lehotsky, Ákos; Haidegger, Tamás; Benyó, Balázs

    2011-03-01

    Hospital Acquired Infections (HAI) represent the fourth leading cause of death in the United States, and claims hundreds of thousands of lives annually in the rest of the world. This paper presents a novel low-cost mobile device|called Stery-Hand|that helps to avoid HAI by improving hand hygiene control through providing an objective evaluation of the quality of hand washing. The use of the system is intuitive: having performed hand washing with a soap mixed with UV re ective powder, the skin appears brighter in UV illumination on the disinfected surfaces. Washed hands are inserted into the Stery-Hand box, where a digital image is taken under UV lighting. Automated image processing algorithms are employed in three steps to evaluate the quality of hand washing. First, the contour of the hand is extracted in order to distinguish the hand from the background. Next, a semi-supervised clustering algorithm classies the pixels of the hand into three groups, corresponding to clean, partially clean and dirty areas. The clustering algorithm is derived from the histogram-based quick fuzzy c-means approach, using a priori information extracted from reference images, evaluated by experts. Finally, the identied areas are adjusted to suppress shading eects, and quantied in order to give a verdict on hand disinfection quality. The proposed methodology was validated through tests using hundreds of images recorded in our laboratory. The proposed system was found robust and accurate, producing correct estimation for over 98% of the test cases. Stery-Hand may be employed in general practice, and it may also serve educational purposes.

  15. High-sensitivity CCD-based x-ray detector

    International Nuclear Information System (INIS)

    The detector is designed for imaging measurements requiring relatively high sensitivity and high spatial resolution. The detector can discriminate single X-ray photons, yet has the wide dynamic range (∼10000:1) associated with integrating detectors. A GdO2S2 phosphor screen converts the incoming X-ray image into an optical image. The optical image is coupled (without demagnification) to the CCD image sensor using a fiber optic faceplate. The CCD (Philips Semiconductors) has an area of 4.9 x 8.6 cm with 4000 x 7000 12 μm pixels. A single 12 keV X-ray photon produces a signal of 100 e-. With 2 x 2 pixel binning, the total noise per 24 μm pixel in a 100 s image is ∼30 e-, the detective quantum efficiency is >0.6 at 1 X-ray photon per pixel, and the full image can be read out in <4 s. The spatial resolution is 50 μm. The CCD readout system is fully computer-controlled, allowing flexible operation in time-resolved experiments. The detector has been characterized using visible-light images, X-ray images and time-resolved muscle diffraction measurements.

  16. Aerial Image over Flint Hills National Wildlife Refuge, Acquired on March 22, 1950 (Frame 1686)

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Georeferenced image, acquired on March 22, 1950, over a portion of the Flint Hills National Wildlife Refuge. Image covers the central and western portions of the...

  17. Aerial Image over Flint Hills National Wildlife Refuge, Acquired on March 22, 1950 (Frame 1656)

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Georeferenced image, acquired on March 22, 1950, over a portion of the Flint Hills National Wildlife Refuge. Image covers the eastern portion of the refuge...

  18. Aerial Image over Flint Hills National Wildlife Refuge, Acquired on March 22, 1950 (Frame 1685)

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Georeferenced image, acquired on March 22, 1950, over a portion of the Flint Hills National Wildlife Refuge. Image covers the central portion of the refuge...

  19. Aerial Image over Flint Hills National Wildlife Refuge, Acquired on March 22, 1950 (Frame 1655)

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Georeferenced image, acquired on March 22, 1950, over a portion of the Flint Hills National Wildlife Refuge. Image covers the eastern portion of the refuge...

  20. Aerial Image over Flint Hills National Wildlife Refuge, Acquired on April 14, 1948 (Frame 1154)

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Georeferenced image, acquired on April 14, 1948, over a portion of the Flint Hills National Wildlife Refuge. Image covers the eastern portion of the refuge...

  1. Aerial Image over Ouray National Wildlife Refuge, Acquired on August 27, 1965 (Frame 131)

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Georeferenced image, acquired on August 27, 1965 over a portion of the Ouray National Wildlife Refuge. Image covers the northern portion of the refuge including...

  2. Aerial Image over Flint Hills National Wildlife Refuge, Acquired on April 14, 1948 (Frame 1155)

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Georeferenced image, acquired on April 14, 1948, over a portion of the Flint Hills National Wildlife Refuge. Image covers the eastern portion of the refuge...

  3. Building Extraction from DSM Acquired by Airborne 3D Image

    Institute of Scientific and Technical Information of China (English)

    YOU Hongjian; LI Shukai

    2003-01-01

    Segmentation and edge regulation are studied deeply to extract buildings from DSM data produced in this paper. Building segmentation is the first step to extract buildings, and a new segmentation method-adaptive iterative segmentation considering ratio mean square-is proposed to extract the contour of buildings effectively. A sub-image (such as 50× 50 pixels )of the image is processed in sequence,the average gray level and its ratio mean square are calculated first, then threshold of the sub-image is selected by using iterative threshold segmentation. The current pixel is segmented according to the threshold, the aver-age gray level and the ratio mean square of the sub-image. The edge points of the building are grouped according to the azimuth of neighbor points, and then the optimal azimuth of the points that belong to the same group can be calculated by using line interpolation.

  4. Lensless CCD-based fluorometer using a micromachined optical Soller collimator

    NARCIS (Netherlands)

    Balsam, Joshua; Ossandon, Miguel; Kostov, Yordan; Bruck, Hugh Alan; Rasooly, Avraham

    2011-01-01

    In this paper, we describe a simple charge-coupled device (CCD) based lensless fluorometer with sensitivity in the range of current ELISA plate readers. In our lensfree fluorometer, a multi-wavelength LED light source was used for fluorophore excitation. To collimate the light, we developed a simple

  5. Series of aerial images over Bear River Migratory Bird Refuge, acquired in 1937

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This dataset includes 40 georeferenced images, acquired on September 25th, October 12th-13th, November 10th and December 1st, 1937 over portions of Bear River...

  6. Series of aerial images over Marais des Cygnes National Wildlife Refuge, acquired in 1950

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This dataset includes 10 georeferenced images, acquired on July 13, 1950 over portions of Marais des Cygnes National Refuge in eastern Kansas. This data set is a...

  7. Series of aerial images over Marais des Cygnes National Wildlife Refuge, acquired in 1957

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This dataset includes 8 georeferenced images, acquired on May 5th, 6th and 26th, 1957 over portions of Marais des Cygnes National Refuge in eastern Kansas. This...

  8. Series of Aerial Images over Flint Hills National Wildlife Refuge, Acquired on November 20, 1969.

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This data set includes 19 Georeferenced images, acquired on November 20, 1969, over Flint Hills National Wildlife Refuge. The frames were downloaded from Earth...

  9. LED characterization for development of on-board calibration unit of CCD-based advanced wide-field sensor camera of Resourcesat-2A

    Science.gov (United States)

    Chatterjee, Abhijit; Verma, Anurag

    2016-05-01

    The Advanced Wide Field Sensor (AWiFS) camera caters to high temporal resolution requirement of Resourcesat-2A mission with repeativity of 5 days. The AWiFS camera consists of four spectral bands, three in the visible and near IR and one in the short wave infrared. The imaging concept in VNIR bands is based on push broom scanning that uses linear array silicon charge coupled device (CCD) based Focal Plane Array (FPA). On-Board Calibration unit for these CCD based FPAs is used to monitor any degradation in FPA during entire mission life. Four LEDs are operated in constant current mode and 16 different light intensity levels are generated by electronically changing exposure of CCD throughout the calibration cycle. This paper describes experimental setup and characterization results of various flight model visible LEDs (λP=650nm) for development of On-Board Calibration unit of Advanced Wide Field Sensor (AWiFS) camera of RESOURCESAT-2A. Various LED configurations have been studied to meet dynamic range coverage of 6000 pixels silicon CCD based focal plane array from 20% to 60% of saturation during night pass of the satellite to identify degradation of detector elements. The paper also explains comparison of simulation and experimental results of CCD output profile at different LED combinations in constant current mode.

  10. RF Device for Acquiring Images of the Human Body

    Science.gov (United States)

    Gaier, Todd C.; McGrath, William R.

    2010-01-01

    A safe, non-invasive method for forming images through clothing of large groups of people, in order to search for concealed weapons either made of metal or not, has been developed. A millimeter wavelength scanner designed in a unique, ring-shaped configuration can obtain a full 360 image of the body with a resolution of less than a millimeter in only a few seconds. Millimeter waves readily penetrate normal clothing, but are highly reflected by the human body and concealed objects. Millimeter wave signals are nonionizing and are harmless to human tissues when used at low power levels. The imager (see figure) consists of a thin base that supports a small-diameter vertical post about 7 ft (=2.13 m) tall. Attached to the post is a square-shaped ring 2 in. (=5 cm) wide and 3 ft (=91 cm) on a side. The ring is oriented horizontally, and is supported halfway along one side by a connection to a linear bearing on the vertical post. A planar RF circuit board is mounted to the inside of each side of the ring. Each circuit board contains an array of 30 receivers, one transmitter, and digitization electronics. Each array element has a printed-circuit patch antenna coupled to a pair of mixers by a 90 coupler. The mixers receive a reference local oscillator signal to a subharmonic of the transmitter frequency. A single local oscillator line feeds all 30 receivers on the board. The resulting MHz IF signals are amplified and carried to the edge of the board where they are demodulated and digitized. The transmitted signal is derived from the local oscillator at a frequency offset determined by a crystal oscillator. One antenna centrally located on each side of the square ring provides the source illumination power. The total transmitted power is less than 100 mW, resulting in an exposure level that is completely safe to humans. The output signals from all four circuit boards are fed via serial connection to a data processing computer. The computer processes the approximately 1-MB

  11. Underwater topography detection of Shuangzi Reefs with SAR images acquired in different time

    Institute of Scientific and Technical Information of China (English)

    YANG Jungang; ZHANG Jie; MENG Junmin

    2007-01-01

    Imaging mechanism of underwater topography by SAR and a underwater topography SAR detection model built on the theory of underwater topography detection with SAR image presented by Yuan Yeli are used to detect the underwater topography of Shuangzi Reefs in the Nansha Islands with three scenes of SAR images acquired in different time. Detection results of three SAR images are compared with the chart topography and the detection errors are analyzed. Underwater topography detection experiments of Shuangzi Reefs show that the detection model is practicable. The detection results indicate that SAR images acquired in different time also can be used to detect the underwater topography, and the detection results are affected by the ocean conditions in the SAR acquiring time.

  12. Hounsfield unit recovery in clinical cone beam CT images of the thorax acquired for image guided radiation therapy

    DEFF Research Database (Denmark)

    Thing, Rune Slot; Bernchou, Uffe; Mainegra-Hing, Ernesto;

    2016-01-01

    A comprehensive artefact correction method for clinical cone beam CT (CBCT) images acquired for image guided radiation therapy (IGRT) on a commercial system is presented. The method is demonstrated to reduce artefacts and recover CT-like Hounsfield units (HU) in reconstructed CBCT images of five...

  13. IT Infrastructure to Support the Secondary Use of Routinely Acquired Clinical Imaging Data for Research

    NARCIS (Netherlands)

    K.Y.E. Leung (Esther); F. van der Lijn (Fedde); H.A. Vrooman (Henri); M.C.J.M. Sturkenboom (Miriam); W.J. Niessen (Wiro)

    2014-01-01

    textabstractWe propose an infrastructure for the automated anonymization, extraction and processing of image data stored in clinical data repositories to make routinely acquired imaging data available for research purposes. The automated system, which was tested in the context of analyzing routinely

  14. Imaging of community-acquired pneumonia: Roles of imaging examinations, imaging diagnosis of specific pathogens and discrimination from noninfectious diseases

    Institute of Scientific and Technical Information of China (English)

    Atsushi; Nambu; Katsura; Ozawa; Noriko; Kobayashi; Masao; Tago

    2014-01-01

    This article reviews roles of imaging examinations in the management of community-acquired pneumonia(CAP), imaging diagnosis of specific CAP and discrimination between CAP and noninfectious diseases. Chest radiography is usually enough to confirm the diagnosis of CAP, whereas computed tomography is required to suggest specific pathogens and to discriminate from noninfectious diseases. Mycoplasma pneumoniae pneumonia, tuberculosis, Pneumocystis jirovecii pneumonia and some cases of viral pneumonia sometimes show specific imaging findings. Peribronchial nodules, especially tree-in-bud appearance, are fairly specific for infection. Evidences of organization, such as concavity of the opacities, traction bronchiectasis, visualization of air bronchograms over the entire length of the bronchi, or mild parenchymal distortion are suggestive of organizing pneumonia. We will introduce tips to effectively make use of imaging examinations in the management of CAP.

  15. Evaluation of the reconstruction of image acquired from CT simulator to reduce metal artifact

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Ji Hun; Park, Jin Hong; Choi, Byung Don; Won, Hui Su; Chang, Nam Jun; Goo, Jang Hyun; Hong, Joo Wan [Dept. of Radiation Oncology, Seoul national university bundang hospital, Sungnam (Korea, Republic of)

    2014-12-15

    This study presents the usefulness assessment of metal artifact reduction for orthopedic implants(O-MAR) to decrease metal artifacts from materials with high density when acquired CT images. By CT simulator, original CT images were acquired from Gammex and Rando phantom and those phantoms inserted with high density materials were scanned for other CT images with metal artifacts and then O-MAR was applied to those images, respectively. To evaluate CT images using Gammex phantom, 5 regions of interest(ROIs) were placed at 5 organs and 3 ROIs were set up at points affected by artifacts. The averages of standard deviation(SD) and CT numbers were compared with a plan using original image. For assessment of variations in dose of tissue around materials with high density, the volume of a cylindrical shape was designed at 3 places in images acquired from Rando phantom by Eclipse. With 6 MV, 7-fields, 15x15cm{sup 2} and 100 cGy per fraction, treatment planning was created and the mean dose were compared with a plan using original image. In the test with the Gammex phantom, CT numbers had a few difference at established points and especially 3 points affected by artifacts had most of the same figures. In the case of O-MAR image, the more reduction in SD appeared at all of 8 points than non O-MAR image. In the test using the Rando Phantom, the variations in dose of tissue around high density materials had a few difference between original CT image and CT image with O-MAR. The CT images using O-MAR were acquired clearly at the boundary of tissue around high density materials and applying O-MAR was useful for correcting CT numbers.

  16. A novel super resolution scheme to acquire and process satellite images

    Science.gov (United States)

    Yin, Dong-yu; Su, Xiao-feng; Lin, Jian-chun; Wang, Gan-quan; Kuang, Ding-bo

    2013-09-01

    Geosynchronous satellite has obvious limitations for the weight and the scale of payloads, and large aperture optical system is not permitted. The optical diffraction limit of small aperture optical system has an adverse impact on the resolution of the acquired images. Therefore, how to get high resolution images using super-resolution technique with the acquired low resolution images becomes a popular problem investigated by researchers. Here, we present a novel scheme to acquire low resolution images and process them to achieve a high resolution image. Firstly, to acquire low resolution images, we adopt a special arrangement pattern of four CCD staggered arrays on the focal plane in the remote sensing satellite framework .These four CCD linear arrays are parallelized with a 0.25√2 pixel shift along the CCD direction and a 1.25 pixel shift along the scanning direction. The rotation angle between the two directions is 45 degree. The tilting sampling mode and the special arrangement pattern allow the sensor to acquire images with a smaller sampling interval which can give the resolution a greater enhancement. Secondly, to reconstruct a high resolution image of pretty good quality with a magnification factor 4, we propose a novel algorithm based on the iterative-interpolation super resolution algorithm (IISR) and the new edge-directed interpolation algorithm (NEDI). The new algorithm makes a critical improvement to NEDI and introduces it into the multi-frame interpolation in IISR. The algorithm can preserve the edges well and requires a relatively small number of low-resolution images to achieve better reconstruction accuracy .In the last part of the paper, we carry out a simulation experiment, and use MSE as the quality measure. The results demonstrate that our new scheme substantially improves the image resolution with both better quantitative quality and visual quality compared with some previous normal methods.

  17. Hounsfield unit recovery in clinical cone beam CT images of the thorax acquired for image guided radiation therapy

    Science.gov (United States)

    Slot Thing, Rune; Bernchou, Uffe; Mainegra-Hing, Ernesto; Hansen, Olfred; Brink, Carsten

    2016-08-01

    A comprehensive artefact correction method for clinical cone beam CT (CBCT) images acquired for image guided radiation therapy (IGRT) on a commercial system is presented. The method is demonstrated to reduce artefacts and recover CT-like Hounsfield units (HU) in reconstructed CBCT images of five lung cancer patients. Projection image based artefact corrections of image lag, detector scatter, body scatter and beam hardening are described and applied to CBCT images of five lung cancer patients. Image quality is evaluated through visual appearance of the reconstructed images, HU-correspondence with the planning CT images, and total volume HU error. Artefacts are reduced and CT-like HUs are recovered in the artefact corrected CBCT images. Visual inspection confirms that artefacts are indeed suppressed by the proposed method, and the HU root mean square difference between reconstructed CBCTs and the reference CT images are reduced by 31% when using the artefact corrections compared to the standard clinical CBCT reconstruction. A versatile artefact correction method for clinical CBCT images acquired for IGRT has been developed. HU values are recovered in the corrected CBCT images. The proposed method relies on post processing of clinical projection images, and does not require patient specific optimisation. It is thus a powerful tool for image quality improvement of large numbers of CBCT images.

  18. Photometric correction for an optical CCD-based system based on the sparsity of an eight-neighborhood gray gradient.

    Science.gov (United States)

    Zhang, Yuzhong; Zhang, Yan

    2016-07-01

    In an optical measurement and analysis system based on a CCD, due to the existence of optical vignetting and natural vignetting, photometric distortion, in which the intensity falls off away from the image center, affects the subsequent processing and measuring precision severely. To deal with this problem, an easy and straightforward method used for photometric distortion correction is presented in this paper. This method introduces a simple polynomial fitting model of the photometric distortion function and employs a particle swarm optimization algorithm to get these model parameters by means of a minimizing eight-neighborhood gray gradient. Compared with conventional calibration methods, this method can obtain the profile information of photometric distortion from only a single common image captured by the optical CCD-based system, with no need for a uniform luminance area source used as a standard reference source and relevant optical and geometric parameters in advance. To illustrate the applicability of this method, numerical simulations and photometric distortions with different lens parameters are evaluated using this method in this paper. Moreover, the application example of temperature field correction for casting billets also demonstrates the effectiveness of this method. The experimental results show that the proposed method is able to achieve the maximum absolute error for vignetting estimation of 0.0765 and the relative error for vignetting estimation from different background images of 3.86%. PMID:27409217

  19. Precision Agriculture: Using Low-Cost Systems to Acquire Low-Altitude Images.

    Science.gov (United States)

    Ponti, Moacir; Chaves, Arthur A; Jorge, Fabio R; Costa, Gabriel B P; Colturato, Adimara; Branco, Kalinka R L J C

    2016-01-01

    Low cost remote sensing imagery has the potential to make precision farming feasible in developing countries. In this article, the authors describe image acquisition from eucalyptus, bean, and sugarcane crops acquired by low-cost and low-altitude systems. They use different approaches to handle low-altitude images in both the RGB and NIR (near-infrared) bands to estimate and quantify plantation areas. PMID:27514030

  20. An approach of DSM generation from multi-view images acquired by UAVs

    Science.gov (United States)

    Hu, DaTian; Ai, Mingyao; Hu, Qingwu; Li, Jiayuan

    2016-03-01

    In the past few years, for its lower-cost, safer and high-resolution images, unmanned aerial vehicles (UAVs) demonstrated great potential for photogrammetric measurements in numerous application fields. Nevertheless, these images are often affected by large rotation, big viewpoint change as well as small overlaps, in which case traditional procedure are not able to orientate images or generate reliable Digital Generation Models (DSM). This paper introduces the whole procedure of the DSM generation, which comprehensively utilizes advantage of both computer vision and multi-image matching algorithms in extracting points and generating a dense DSM. Experiment shows that, based on this procedure, it can quickly extract points from the high-resolution images acquired by UAVs with high location accuracy.

  1. Non-negative factor analysis supporting the interpretation of elemental distribution images acquired by XRF

    OpenAIRE

    Alfeld, Matthias; Wahabzada, Mirwaes; Bauckhage, Christian; Kersting, Kristian; Wellenreuther, Gerd; Falkenberg, Gerald

    2014-01-01

    Stacks of elemental distribution images acquired by XRF can be difficult to interpret, if they contain high degrees of redundancy and components differing in their quantitative but not qualitative elemental composition. Factor analysis, mainly in the form of Principal Component Analysis (PCA), has been used to reduce the level of redundancy and highlight correlations. PCA, however, does not yield physically meaningful representations as they often contain negative values. This limitation can ...

  2. Estimating plant traits of grasslands from UAV-acquired hyperspectral images

    OpenAIRE

    Capolupo, Alessandra; Kooistra, Lammert; Berendonk, Clara; Boccia, Lorenzo; Suomalainen, Juha

    2015-01-01

    Grassland ecosystems cover around 40% of the entire Earth's surface. Therefore, it is necessary to guarantee good grassland management at field scale in order to improve its conservation and to achieve optimal growth. This study identified the most appropriate statistical strategy, between partial least squares regression (PLSR) and narrow vegetation indices, for estimating the structural and biochemical grassland traits from UAV-acquired hyperspectral images. Moreover, the influence of ferti...

  3. Estimating Plant Traits of Grasslands from UAV-Acquired Hyperspectral Images: A Comparison of Statistical Approaches

    OpenAIRE

    Alessandra Capolupo; Lammert Kooistra; Clara Berendonk; Lorenzo Boccia; Juha Suomalainen

    2015-01-01

    Grassland ecosystems cover around 40% of the entire Earth’s surface. Therefore, it is necessary to guarantee good grassland management at field scale in order to improve its conservation and to achieve optimal growth. This study identified the most appropriate statistical strategy, between partial least squares regression (PLSR) and narrow vegetation indices, for estimating the structural and biochemical grassland traits from UAV-acquired hyperspectral images. Moreover, the influence of ferti...

  4. Complications of sporadic, hereditary, and acquired renal cysts: cross-sectional imaging findings.

    Science.gov (United States)

    Tonolini, Massimo; Rigiroli, Francesca; Villa, Federica; Bianco, Roberto

    2014-01-01

    Commonly encountered in the general adult and elderly population, in most cases simple renal cysts are confidently diagnosed on imaging studies and do not require further workup or treatment. However, large or growing renal cysts sometimes cause symptoms or signs such as hypertension, palpable mass, flank or abdominal pain, obstructive uropathy, and hematuria, which may indicate the need for minimally invasive percutaneous or laparoscopic treatment. Furthermore, severe complications such as cystic hemorrhage, rupture, or superinfection may occur, particularly in patients with polycystic renal disorders, either hereditary (namely adult polycystic kidney diseases) or acquired in chronic renal failure. This pictorial essay reviews and discusses the cross-sectional imaging appearances of symptomatic and complicated sporadic, hereditary, and acquired renal cysts. Early cross-sectional imaging with multidetector computed tomography or magnetic resonance imaging or both, including contrast enhancement unless contraindicated by renal dysfunction, is warranted to investigate clinical and laboratory signs suggesting retroperitoneal hemorrhage or infection in patients with pre-existent renal cysts, particularly if large, multiple, or hereditary.

  5. Image processing and classification procedures for analysis of sub-decimeter imagery acquired with an unmanned aircraft over arid rangelands

    Science.gov (United States)

    Using five centimeter resolution images acquired with an unmanned aircraft system (UAS), we developed and evaluated an image processing workflow that included the integration of resolution-appropriate field sampling, feature selection, object-based image analysis, and processing approaches for UAS i...

  6. CNN intelligent early warning for apple skin lesion image acquired by infrared video sensors

    Institute of Scientific and Technical Information of China (English)

    谭文学

    2016-01-01

    Video sensors and agricultural IoT ( internet of things) have been widely used in the informa-tionalized orchards.In order to realize intelligent-unattended early warning for disease-pest, this pa-per presents convolutional neural network ( CNN) early warning for apple skin lesion image, which is real-time acquired by infrared video sensor.More specifically, as to skin lesion image, a suite of processing methods is devised to simulate the disturbance of variable orientation and light condition which occurs in orchards.It designs a method to recognize apple pathologic images based on CNN, and formulates a self-adaptive momentum rule to update CNN parameters.For example, a series of experiments are carried out on the recognition of fruit lesion image of apple trees for early warning. The results demonstrate that compared with the shallow learning algorithms and other involved, well-known deep learning methods, the recognition accuracy of the proposal is up to 96.08%, with a fairly quick convergence, and it also presents satisfying smoothness and stableness after conver-gence.In addition, statistics on different benchmark datasets prove that it is fairly effective to other image patterns concerned.

  7. Series of Aerial Images over Bear River Migratory Bird Refuge, Acquired on November 7th and 9th, 1965.

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This data set includes 22 georeferenced images, acquired on November 7th and 9th, 1965, over portions of Bear River Migratory Bird Refuge, in Box Elder County,...

  8. Optimal imaging strategy for community-acquired Staphylococcus aureus musculoskeletal infections in children

    International Nuclear Information System (INIS)

    Invasive musculoskeletal infections from community-acquired methicillin-resistant and methicillin-susceptible Staphylococcus aureus (CA-SA) are increasingly encountered in children. Imaging is frequently requested in these children for diagnosis and planning of therapeutic interventions. To appraise the diagnostic efficacy of imaging practices performed for CA-SA osteomyelitis and its complications. A retrospective review was conducted of the clinical charts and imaging studies of CA-SA osteomyelitis cases since 2001 at a large children's hospital. Of 199 children diagnosed with CA-SA osteomyelitis, 160 underwent MRI examination and 35 underwent bone scintigraphy. The sensitivity of MRI and bone scintigraphy for CA-SA osteomyelitis was 98% and 53%, respectively. In all discordant cases, MRI was correct compared to bone scintigraphy. Extraosseous complications of CA-SA osteomyelitis detected only by MRI included subperiosteal abscesses (n = 77), pyomyositis (n = 43), septic arthritis (n = 31), and deep venous thrombosis (n = 12). MRI is the preferred imaging modality for the investigation of pediatric CA-SA musculoskeletal infection because it offers superior sensitivity for osteomyelitis compared to bone scintigraphy and detects extraosseous complications that occur in a substantial proportion of patients. (orig.)

  9. Optimal imaging strategy for community-acquired Staphylococcus aureus musculoskeletal infections in children

    Energy Technology Data Exchange (ETDEWEB)

    Browne, Lorna P.; Cassady, Christopher I.; Krishnamurthy, Rajesh; Guillerman, R.P. [Texas Children' s Hospital, Edward B. Singleton Department of Diagnostic Imaging, Houston, TX (United States); Mason, Edward O.; Kaplan, Sheldon L. [Texas Children' s Hospital, Department of Pediatrics, Baylor College of Medicine, Infectious Disease Service, Houston, TX (United States)

    2008-08-15

    Invasive musculoskeletal infections from community-acquired methicillin-resistant and methicillin-susceptible Staphylococcus aureus (CA-SA) are increasingly encountered in children. Imaging is frequently requested in these children for diagnosis and planning of therapeutic interventions. To appraise the diagnostic efficacy of imaging practices performed for CA-SA osteomyelitis and its complications. A retrospective review was conducted of the clinical charts and imaging studies of CA-SA osteomyelitis cases since 2001 at a large children's hospital. Of 199 children diagnosed with CA-SA osteomyelitis, 160 underwent MRI examination and 35 underwent bone scintigraphy. The sensitivity of MRI and bone scintigraphy for CA-SA osteomyelitis was 98% and 53%, respectively. In all discordant cases, MRI was correct compared to bone scintigraphy. Extraosseous complications of CA-SA osteomyelitis detected only by MRI included subperiosteal abscesses (n = 77), pyomyositis (n = 43), septic arthritis (n = 31), and deep venous thrombosis (n = 12). MRI is the preferred imaging modality for the investigation of pediatric CA-SA musculoskeletal infection because it offers superior sensitivity for osteomyelitis compared to bone scintigraphy and detects extraosseous complications that occur in a substantial proportion of patients. (orig.)

  10. Color calibration of swine gastrointestinal tract images acquired by radial imaging capsule endoscope

    Science.gov (United States)

    Ou-Yang, Mang; Jeng, Wei-De; Lai, Chien-Cheng; Wu, Hsien-Ming; Lin, Jyh-Hung

    2016-01-01

    The type of illumination systems and color filters used typically generate varying levels of color difference in capsule endoscopes, which influence medical diagnoses. In order to calibrate the color difference caused by the optical system, this study applied a radial imaging capsule endoscope (RICE) to photograph standard color charts, which were then employed to calculate the color gamut of RICE. Color gamut was also measured using a spectrometer in order to get a high-precision color information, and the results obtained using both methods were compared. Subsequently, color-correction methods, namely polynomial transform and conformal mapping, were used to improve the color difference. Before color calibration, the color difference value caused by the influences of optical systems in RICE was 21.45±1.09. Through the proposed polynomial transformation, the color difference could be reduced effectively to 1.53±0.07. Compared to another proposed conformal mapping, the color difference value was substantially reduced to 1.32±0.11, and the color difference is imperceptible for human eye because it is color correction was achieved using this algorithm combined with a field-programmable gate array, and the results of the color correction can be viewed from real-time images.

  11. MaterialCloning: Acquiring Elasticity Parameters from Images for Medical Applications.

    Science.gov (United States)

    Yang, Shan; Lin, Ming C

    2016-09-01

    We present a practical approach for automatically estimating the material properties of soft bodies from two sets of images, taken before and after deformation. We reconstruct 3D geometry from the given sets of multiple-view images; we use a coupled simulation-optimization-identification framework to deform one soft body at its original, non-deformed state to match the deformed geometry of the same object in its deformed state. For shape correspondence, we use a distance-based error metric to compare the estimated deformation fields against the actual deformation field from the reconstructed geometry. The optimal set of material parameters is thereby determined by minimizing the error metric function. This method can simultaneously recover the elasticity parameters of multiple types of soft bodies using Finite Element Method-based simulation (of either linear or nonlinear materials undergoing large deformation) and particle-swarm optimization methods. We demonstrate this approach on real-time interaction with virtual organs in patient-specific surgical simulation, using parameters acquired from low-resolution medical images. We also highlight the results on physics-based animation of virtual objects using sketches from an artist's conception. PMID:26661471

  12. Physical Activity Recognition Based on Motion in Images Acquired by a Wearable Camera.

    Science.gov (United States)

    Zhang, Hong; Li, Lu; Jia, Wenyan; Fernstrom, John D; Sclabassi, Robert J; Mao, Zhi-Hong; Sun, Mingui

    2011-06-01

    A new technique to extract and evaluate physical activity patterns from image sequences captured by a wearable camera is presented in this paper. Unlike standard activity recognition schemes, the video data captured by our device do not include the wearer him/herself. The physical activity of the wearer, such as walking or exercising, is analyzed indirectly through the camera motion extracted from the acquired video frames. Two key tasks, pixel correspondence identification and motion feature extraction, are studied to recognize activity patterns. We utilize a multiscale approach to identify pixel correspondences. When compared with the existing methods such as the Good Features detector and the Speed-up Robust Feature (SURF) detector, our technique is more accurate and computationally efficient. Once the pixel correspondences are determined which define representative motion vectors, we build a set of activity pattern features based on motion statistics in each frame. Finally, the physical activity of the person wearing a camera is determined according to the global motion distribution in the video. Our algorithms are tested using different machine learning techniques such as the K-Nearest Neighbor (KNN), Naive Bayesian and Support Vector Machine (SVM). The results show that many types of physical activities can be recognized from field acquired real-world video. Our results also indicate that, with a design of specific motion features in the input vectors, different classifiers can be used successfully with similar performances.

  13. 99mTc-ECD brain SPECT imaging in patients with acquired immunodeficiency syndromes

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    In order to investigate the changes of regional cerebral blood flow(rCBF) in patients with acquired immunodeficiency syndromes (AIDS), 99mTc-ECDbrain SPECT imaging was performed in 5 patients with AIDS and 16 sex and agematched normal controls, and the rCBF percentages compared to the cerebellum werecalculated using a semi-quantitative processing software. Hypoperfusions in the rightand left frontal, temporal, porietal lobe, basal ganglia and left thalamus were seen in1 patient with dementia. Hypoperfusions in the right and left frontal and temporallobe were seen in 4 asymptomatic patients. The rCBF in the right and left frontal.temporal, porietal lobe, basal ganglia and thalamus, front and pons were decreasedsignificantly in patients with AIDS than those of the control subjects (p <0.005). Itis concluded that there exists reduced cortico-subcortical rCBF in AIDS patients.``

  14. Improvements to the three-color optical CCD-based pyrometer system

    International Nuclear Information System (INIS)

    We put forward an improved three-color measurement scheme with a color CCD sensor using the combination of effective wavelengths and blackbody calibrations. The process of effective wavelengths realizes the separation of the emissivity function from the measurement integral equation. This improved method not only effectively avoids errors arising from the traditional process adopting the basic wavelengths, but also simplifies the complex integral calculations. For a blackbody or graybody, the measurement performance of the pyrometer was experimentally investigated from the point of the temperature sensitivity. The results show that narrowing the spectrum bandwidth with different bandpass spectral filters may improve the temperature sensitivities. The spectrum adjustment not only makes the linear emissivity more suitable in the narrower waveband, but also reduces the numerical uncertainty of the effective wavelengths. For nongray objects, the effects of the numerical uncertainty of the effective wavelengths to measurements were quantificationally evaluated at different measurement conditions (different temperatures, emissivities, and spectrums). The results indicate that the reference values of 584, 555, and 511nm or 607, 560, and 506nm of the effective wavelengths are reasonable for the present system with the modified spectral response using Filter 1 or Filter 2. The maximum calculation errors arising from the reference effective wavelengths are less than 1.6%. In this paper, the technical realization steps of the improved method are also described. The measurement experiments of a metal sample in hot environments were carried out to further verify the applicability of this improved CCD-based pyrometer. The results agreed well with the spectrometer-based results.

  15. Method for 3D Object Reconstruction Using Several Portion of 2D Images from the Different Aspects Acquired with Image Scopes Included in the Fiber Retractor

    Directory of Open Access Journals (Sweden)

    Kohei Arai

    2012-12-01

    Full Text Available Method for 3D object reconstruction using several portions of 2D images from the different aspects which are acquired with image scopes included in the fiber retractor is proposed. Experimental results show a great possibilityfor reconstruction of acceptable quality of 3D object on the computer with several imageswhich are viewed from the different aspects of 2D images.

  16. Traffic sign detection in MLS acquired point clouds for geometric and image-based semantic inventory

    Science.gov (United States)

    Soilán, Mario; Riveiro, Belén; Martínez-Sánchez, Joaquín; Arias, Pedro

    2016-04-01

    Nowadays, mobile laser scanning has become a valid technology for infrastructure inspection. This technology permits collecting accurate 3D point clouds of urban and road environments and the geometric and semantic analysis of data became an active research topic in the last years. This paper focuses on the detection of vertical traffic signs in 3D point clouds acquired by a LYNX Mobile Mapper system, comprised of laser scanning and RGB cameras. Each traffic sign is automatically detected in the LiDAR point cloud, and its main geometric parameters can be automatically extracted, therefore aiding the inventory process. Furthermore, the 3D position of traffic signs are reprojected on the 2D images, which are spatially and temporally synced with the point cloud. Image analysis allows for recognizing the traffic sign semantics using machine learning approaches. The presented method was tested in road and urban scenarios in Galicia (Spain). The recall results for traffic sign detection are close to 98%, and existing false positives can be easily filtered after point cloud projection. Finally, the lack of a large, publicly available Spanish traffic sign database is pointed out.

  17. Reliability of Calf Bioelectrical Impedance Spectroscopy and Magnetic-Resonance-Imaging-Acquired Skeletal Muscle Hydration Measures in Healthy People

    OpenAIRE

    Anuradha Sawant; House, Andrew A; Chesworth, Bert M.; Joseph Gati; Robert Lindsay; Connelly, Denise M.; Robert Bartha; Overend, Tom J.

    2013-01-01

    Purpose. The purpose of this study was to investigate the test-retest reliability, relative variability, and agreement between calf bioelectrical impedance-spectroscopy (cBIS) acquired extracellular fluid (ECF), intracellular fluid (ICF), total water and the ratio of ECF : ICF, magnetic-resonance-imaging (MRI) acquired transverse relaxation times (T2), and apparent diffusion coefficient (ADC) of calf muscles of the same segment in healthy individuals. Methods. Muscle hydration measures were c...

  18. Dynamic magnetic resonance imaging of endoscopic third ventriculostomy patency with differently acquired fast imaging with steady-state precession sequences.

    Science.gov (United States)

    Lucic, Milos A; Koprivsek, Katarina; Kozic, Dusko; Spero, Martina; Spirovski, Milena; Lucic, Silvija

    2014-08-16

    The aim of the study was to determine the possibilities of two differently acquired two-dimensional fast imaging with steady-state precession (FISP 2D) magnetic resonance sequences in estimation of the third ventricle floor fenestration patency after endoscopic third ventriculostomy (ETV) in the subjects with aqueductal stenosis/obstruction.Fifty eight subjects (37 males, 21 females, mean age 27 years) with previously successfully performed ETV underwent brain MRI on 1.5T MR imager 3-6 months after the procedure. Two different FISP 2D sequences (one included in the standard vendor provided software package, and the other, experimentally developed by our team) were performed respectively at two fixed slice positions: midsagittal and perpendicular to the ETV fenestration, and displayed in a closed-loop cinematographic format in order to estimate the patency. The ventricular volume reduction has been observed as well.Cerebrospinal fluid (CSF) flow through the ETV fenestration was observed in midsagittal plane with both FISP 2D sequences in 93.11% subjects, while in 6.89% subjects the dynamic CSF flow MRI was inconclusive. In the perpendicular plane CSF flow through the ETV fenestration was visible only by use of experimentally developed FISP 2D (TR30/FA70) sequence. Postoperative volume reduction of lateral and third ventricle was detected in 67.24% subjects.Though both FISP 2D sequences acquired in midsagittal plane may be used to estimate the effects of performed ETV, due to achieved higher CSF pulsatile flow sensitivity, only the use of FISP 2D (TR30/FA70) sequence enables the estimation of the treatment effect in perpendicular plane in the absence of phase-contrast sequences. 

  19. Dynamic Magnetic Resonance Imaging of Endoscopic Third Ventriculostomy Patency With Differently Acquired Fast Imaging With Steady-State Precission Sequences

    Directory of Open Access Journals (Sweden)

    Milos A. Lucic

    2014-08-01

    Full Text Available The aim of the study was to determine the possibilities of two differently acquired two-dimensional fast imaging with steady-state precession (FISP 2D magnetic resonance sequences in estimation of the third ventricle floor fenestration patency after endoscopic third ventriculostomy (ETV in the subjects with aqueductal stenosis/obstruction.Fifty eight subjects (37 males, 21 females, mean age 27 years with previously successfully performed ETV underwent brain MRI on 1.5T MR imager 3-6 months after the procedure. Two different FISP 2D sequences (one included in the standard vendor provided software package, and the other, experimentally developed by our team were performed respectively at two fixed slice positions: midsagittal and perpendicular to the ETV fenestration, and displayed in a closed-loop cinematographic format in order to estimate the patency. The ventricular volume reduction has been observed as well.Cerebrospinal fluid (CSF flow through the ETV fenestration was observed in midsagittal plane with both FISP 2D sequences in 93.11% subjects, while in 6.89% subjects the dynamic CSF flow MRI was inconclusive. In the perpendicular plane CSF flow through the ETV fenestration was visible only by use of experimentally developed FISP 2D (TR30/FA70 sequence. Postoperative volume reduction of lateral and third ventricle was detected in 67.24% subjects.Though both FISP 2D sequences acquired in midsagittal plane may be used to estimate the effects of performed ETV, due to achieved higher CSF pulsatile flow sensitivity, only the use of FISP 2D (TR30/FA70 sequence enables the estimation of the treatment effect in perpendicular plane in the absence of phase-contrast sequences. 

  20. Estimating Plant Traits of Grasslands from UAV-Acquired Hyperspectral Images: A Comparison of Statistical Approaches

    Directory of Open Access Journals (Sweden)

    Alessandra Capolupo

    2015-12-01

    Full Text Available Grassland ecosystems cover around 40% of the entire Earth’s surface. Therefore, it is necessary to guarantee good grassland management at field scale in order to improve its conservation and to achieve optimal growth. This study identified the most appropriate statistical strategy, between partial least squares regression (PLSR and narrow vegetation indices, for estimating the structural and biochemical grassland traits from UAV-acquired hyperspectral images. Moreover, the influence of fertilizers on plant traits for grasslands was analyzed. Hyperspectral data were collected from an experimental field at the farm Haus Riswick, near Kleve in Germany, for two different flight campaigns in May and October. The collected image blocks were geometrically and radiometrically corrected for surface reflectance. Spectral signatures extracted for the plots were adopted to derive grassland traits by computing PLSR and the following narrow vegetation indices: the MERIS Terrestrial Chlorophyll Index (MTCI, the ratio of the Modified Chlorophyll Absorption in Reflectance and Optimized Soil-Adjusted Vegetation Index (MCARI/OSAVI modified by Wu, the Red-edge Chlorophyll Index (CIred-edge, and the Normalized Difference Red Edge (NDRE. PLSR showed promising results for estimating grassland structural traits and gave less satisfying outcomes for the selected chemical traits (crude ash, crude fiber, crude protein, Na, K, metabolic energy. Established relations are not influenced by the type and the amount of fertilization, while they are affected by the grassland health status. PLSR is found to be the best strategy, among the approaches analyzed in this paper, for exploring structural and biochemical features of grasslands. Using UAV-based hyperspectral sensing allows for the highly detailed assessment of grassland experimental plots.

  1. Receiver operating characteristic analysis for the detection of simulated microcalcifications on mammograms using hardcopy images

    Energy Technology Data Exchange (ETDEWEB)

    Lai, C J [Department of Imaging Physics, University of Texas M D Anderson Cancer Center, Houston, Texas (United States); Shaw, Chris C [Department of Imaging Physics, University of Texas M D Anderson Cancer Center, Houston, Texas (United States); Whitman, Gary J [Department of Diagnostic Radiology, University of Texas M D Anderson Cancer Center, Houston, Texas (United States); Yang, Wei T [Department of Diagnostic Radiology, University of Texas M D Anderson Cancer Center, Houston, Texas (United States); Dempsey, Peter J [Department of Diagnostic Radiology, University of Texas M D Anderson Cancer Center, Houston, Texas (United States); Nguyen, Victoria [Department of Diagnostic Radiology, University of Texas M D Anderson Cancer Center, Houston, Texas (United States); Ice, Mary F [Department of Diagnostic Radiology, University of Texas M D Anderson Cancer Center, Houston, Texas (United States)

    2006-08-21

    The aim of this study was to compare mammography systems based on three different detectors-a conventional screen-film (SF) combination, an a-Si/CsI flat-panel (FP)-based detector, and a charge-coupled device (CCD)-based x-ray phosphor-based detector-for their performance in detecting simulated microcalcifications (MCs). 112-150 {mu}m calcium carbonate grains were used to simulate MCs and were overlapped with a slab phantom of simulated 50% adipose/50% glandular breast tissue-equivalent material referred to as the uniform background. For the tissue structure background, 200-250 {mu}m calcium carbonate grains were used and overlapped with an anthropomorphic breast phantom. All MC phantom images were acquired with and without magnification (1.8X). The hardcopy images were reviewed by five mammographers. A five-point confidence level rating was used to score each detection task. Receiver operating characteristic (ROC) analysis was performed, and the areas under the ROC curves (A{sub z}s) were used to compare the performances of the three mammography systems under various conditions. The results showed that, with a uniform background and contact images, the FP-based system performed significantly better than the SF and the CCD-based systems. For magnified images with a uniform background, the SF and the FP-based systems performed equally well and significantly better than the CCD-based system. With tissue structure background and contact images, the SF system performed significantly better than the FP and the CCD-based systems. With magnified images and a tissue structure background, the SF and the CCD-based systems performed equally well and significantly better than the FP-based system. In the detection of MCs in the fibroglandular and the heterogeneously dense regions, no significant differences were found except that the SF system performed significantly better than the CCD-based system in the fibroglandular regions for the contact images.

  2. A CCD-based reader combined with CdS quantum dot-labeled lateral flow strips for ultrasensitive quantitative detection of CagA

    Science.gov (United States)

    Gui, Chen; Wang, Kan; Li, Chao; Dai, Xuan; Cui, Daxiang

    2014-02-01

    Immunochromatographic assays are widely used to detect many analytes. CagA is proved to be associated closely with initiation of gastric carcinoma. Here, we reported that a charge-coupled device (CCD)-based test strip reader combined with CdS quantum dot-labeled lateral flow strips for quantitative detection of CagA was developed, which used 365-nm ultraviolet LED as the excitation light source, and captured the test strip images through an acquisition module. Then, the captured image was transferred to the computer and was processed by a software system. A revised weighted threshold histogram equalization (WTHE) image processing algorithm was applied to analyze the result. CdS quantum dot-labeled lateral flow strips for detection of CagA were prepared. One hundred sera samples from clinical patients with gastric cancer and healthy people were prepared for detection, which demonstrated that the device could realize rapid, stable, and point-of-care detection, with a sensitivity of 20 pg/mL.

  3. Road Signs Detection and Recognition Utilizing Images and 3d Point Cloud Acquired by Mobile Mapping System

    Science.gov (United States)

    Li, Y. H.; Shinohara, T.; Satoh, T.; Tachibana, K.

    2016-06-01

    High-definition and highly accurate road maps are necessary for the realization of automated driving, and road signs are among the most important element in the road map. Therefore, a technique is necessary which can acquire information about all kinds of road signs automatically and efficiently. Due to the continuous technical advancement of Mobile Mapping System (MMS), it has become possible to acquire large number of images and 3d point cloud efficiently with highly precise position information. In this paper, we present an automatic road sign detection and recognition approach utilizing both images and 3D point cloud acquired by MMS. The proposed approach consists of three stages: 1) detection of road signs from images based on their color and shape features using object based image analysis method, 2) filtering out of over detected candidates utilizing size and position information estimated from 3D point cloud, region of candidates and camera information, and 3) road sign recognition using template matching method after shape normalization. The effectiveness of proposed approach was evaluated by testing dataset, acquired from more than 180 km of different types of roads in Japan. The results show a very high success in detection and recognition of road signs, even under the challenging conditions such as discoloration, deformation and in spite of partial occlusions.

  4. ROAD SIGNS DETECTION AND RECOGNITION UTILIZING IMAGES AND 3D POINT CLOUD ACQUIRED BY MOBILE MAPPING SYSTEM

    Directory of Open Access Journals (Sweden)

    Y. H. Li

    2016-06-01

    Full Text Available High-definition and highly accurate road maps are necessary for the realization of automated driving, and road signs are among the most important element in the road map. Therefore, a technique is necessary which can acquire information about all kinds of road signs automatically and efficiently. Due to the continuous technical advancement of Mobile Mapping System (MMS, it has become possible to acquire large number of images and 3d point cloud efficiently with highly precise position information. In this paper, we present an automatic road sign detection and recognition approach utilizing both images and 3D point cloud acquired by MMS. The proposed approach consists of three stages: 1 detection of road signs from images based on their color and shape features using object based image analysis method, 2 filtering out of over detected candidates utilizing size and position information estimated from 3D point cloud, region of candidates and camera information, and 3 road sign recognition using template matching method after shape normalization. The effectiveness of proposed approach was evaluated by testing dataset, acquired from more than 180 km of different types of roads in Japan. The results show a very high success in detection and recognition of road signs, even under the challenging conditions such as discoloration, deformation and in spite of partial occlusions.

  5. Stigma models: Testing hypotheses of how images of Nevada are acquired and values are attached to them

    Energy Technology Data Exchange (ETDEWEB)

    Jenkins-Smith, H.C. [New Mexico Univ., Albuquerque, NM (United States)

    1994-12-01

    This report analyzes data from surveys on the effects that images associated with nuclear power and waste (i.e., nuclear images) have on people`s preference to vacation in Nevada. The analysis was stimulated by a model of imagery and stigma which assumes that information about a potentially hazardous facility generates signals that elicit negative images about the place in which it is located. Individuals give these images negative values (valences) that lessen their desire to vacation, relocate, or retire in that place. The model has been used to argue that the proposed Yucca Mountain high-level nuclear waste repository could elicit images of nuclear waste that would stigmatize Nevada and thus impose substantial economic losses there. This report proposes a revised model that assumes that the acquisition and valuation of images depend on individuals` ideological and cultural predispositions and that the ways in which new images will affect their preferences and behavior partly depend on these predispositions. The report tests these hypotheses: (1) individuals with distinct cultural and ideological predispositions have different propensities for acquiring nuclear images, (2) these people attach different valences to these images, (3) the variations in these valences are important, and (4) the valences of the different categories of images within an individual`s image sets for a place correlate very well. The analysis largely confirms these hypotheses, indicating that the stigma model should be revised to (1) consider the relevant ideological and cultural predispositions of the people who will potentially acquire and attach value to the image, (2) specify the kinds of images that previously attracted people to the host state, and (3) consider interactions between the old and potential new images of the place. 37 refs., 18 figs., 17 tabs.

  6. Stigma models: Testing hypotheses of how images of Nevada are acquired and values are attached to them

    International Nuclear Information System (INIS)

    This report analyzes data from surveys on the effects that images associated with nuclear power and waste (i.e., nuclear images) have on people's preference to vacation in Nevada. The analysis was stimulated by a model of imagery and stigma which assumes that information about a potentially hazardous facility generates signals that elicit negative images about the place in which it is located. Individuals give these images negative values (valences) that lessen their desire to vacation, relocate, or retire in that place. The model has been used to argue that the proposed Yucca Mountain high-level nuclear waste repository could elicit images of nuclear waste that would stigmatize Nevada and thus impose substantial economic losses there. This report proposes a revised model that assumes that the acquisition and valuation of images depend on individuals' ideological and cultural predispositions and that the ways in which new images will affect their preferences and behavior partly depend on these predispositions. The report tests these hypotheses: (1) individuals with distinct cultural and ideological predispositions have different propensities for acquiring nuclear images, (2) these people attach different valences to these images, (3) the variations in these valences are important, and (4) the valences of the different categories of images within an individual's image sets for a place correlate very well. The analysis largely confirms these hypotheses, indicating that the stigma model should be revised to (1) consider the relevant ideological and cultural predispositions of the people who will potentially acquire and attach value to the image, (2) specify the kinds of images that previously attracted people to the host state, and (3) consider interactions between the old and potential new images of the place. 37 refs., 18 figs., 17 tabs

  7. Series of aerial images over Baca National Wildlife Refuge, acquired in 1953

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This data set includes 23 georeferenced and clipped versions of aerial photographs acquired September 29th and October 1st, 1953, over Baca National Wildlife...

  8. Series of aerial images over Monte Vista National Wildlife Refuge, acquired November 1941

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This data set includes 31 georeferenced versions of original black and white aerial photographs acquired in digital form from the National Archives and Records...

  9. Association between muscle hydration measures acquired using bioelectrical impedance spectroscopy and magnetic resonance imaging in healthy and hemodialysis population

    OpenAIRE

    Sawant, Anuradha; House, Andrew A; Chesworth, Bert M.; Connelly, Denise M.; Lindsay, Robert; Gati, Joe; Bartha, Robert; Overend, Tom J.

    2015-01-01

    Abstract Establishing the effect of fluctuating extracellular fluid (ECF) volume on muscle strength in people with end‐stage renal disease (ESRD) on hemodialysis (HD) is essential, as inadequate hydration of the skeletal muscles impacts its strength and endurance. Bioelectrical impedance spectroscopy (BIS) has been a widely used method for estimating ECF volume of a limb or calf segment. Magnetic resonance imaging (MRI)‐acquired transverse relaxation times (T 2) has also been used for estimat...

  10. Radiometric Normalization of Large Airborne Image Data Sets Acquired by Different Sensor Types

    Science.gov (United States)

    Gehrke, S.; Beshah, B. T.

    2016-06-01

    Generating seamless mosaics of aerial images is a particularly challenging task when the mosaic comprises a large number of im-ages, collected over longer periods of time and with different sensors under varying imaging conditions. Such large mosaics typically consist of very heterogeneous image data, both spatially (different terrain types and atmosphere) and temporally (unstable atmo-spheric properties and even changes in land coverage). We present a new radiometric normalization or, respectively, radiometric aerial triangulation approach that takes advantage of our knowledge about each sensor's properties. The current implementation supports medium and large format airborne imaging sensors of the Leica Geosystems family, namely the ADS line-scanner as well as DMC and RCD frame sensors. A hierarchical modelling - with parameters for the overall mosaic, the sensor type, different flight sessions, strips and individual images - allows for adaptation to each sensor's geometric and radiometric properties. Additional parameters at different hierarchy levels can compensate radiome-tric differences of various origins to compensate for shortcomings of the preceding radiometric sensor calibration as well as BRDF and atmospheric corrections. The final, relative normalization is based on radiometric tie points in overlapping images, absolute radiometric control points and image statistics. It is computed in a global least squares adjustment for the entire mosaic by altering each image's histogram using a location-dependent mathematical model. This model involves contrast and brightness corrections at radiometric fix points with bilinear interpolation for corrections in-between. The distribution of the radiometry fixes is adaptive to each image and generally increases with image size, hence enabling optimal local adaptation even for very long image strips as typi-cally captured by a line-scanner sensor. The normalization approach is implemented in HxMap software. It has been

  11. Reliability of Calf Bioelectrical Impedance Spectroscopy and Magnetic-Resonance-Imaging-Acquired Skeletal Muscle Hydration Measures in Healthy People

    Directory of Open Access Journals (Sweden)

    Anuradha Sawant

    2013-01-01

    Full Text Available Purpose. The purpose of this study was to investigate the test-retest reliability, relative variability, and agreement between calf bioelectrical impedance-spectroscopy (cBIS acquired extracellular fluid (ECF, intracellular fluid (ICF, total water and the ratio of ECF : ICF, magnetic-resonance-imaging (MRI acquired transverse relaxation times (T2, and apparent diffusion coefficient (ADC of calf muscles of the same segment in healthy individuals. Methods. Muscle hydration measures were collected in 32 healthy individuals on two occasions and analyzed by a single rater. On both occasions, MRI measures were collected from tibialis anterior (TA, medial (MG, and lateral gastrocnemius (LG and soleus muscles following the cBIS data acquired using XiTRON Hydra 4200 BIS device. The intraclass correlation coefficients (ICC2,1, coefficient of variation (CV, and agreement between MRI and cBIS data were also calculated. Results. ICC2,1 values for cBIS, T2, and ADC ranged from 0.56 to 0.92, 0.96 to 0.99, and 0.05 to 0.56, respectively. Relative variability between measures (CV ranged from 14.6 to 25.6% for the cBIS data and 4.2 to 10.0% for the MRI-acquired data. The ratio of ECF : ICF could significantly predict T2 of TA and soleus muscles. Conclusion. MRI-acquired measures of T2 had the highest test-retest reliability of muscle hydration with the least error and variation on repeated testing. Hence, T2 of a muscle is the most reliable and stable outcome measure for evaluating individual muscle hydration.

  12. Effect of hierarchical deformable motion compensation on image enhancement for DSA acquired via C-ARM

    Science.gov (United States)

    Wei, Liyang; Shen, Dinggang; Kumar, Dinesh; Turlapati, Ram; Suri, Jasjit S.

    2008-02-01

    DSA images suffer from challenges like system X-ray noise and artifacts due to patient movement. In this paper, we present a two-step strategy to improve DSA image quality. First, a hierarchical deformable registration algorithm is used to register the mask frame and the bolus frame before subtraction. Second, the resulted DSA image is further enhanced by background diffusion and nonlinear normalization for better visualization. Two major changes are made in the hierarchical deformable registration algorithm for DSA images: 1) B-Spline is used to represent the deformation field in order to produce the smooth deformation field; 2) two features are defined as the attribute vector for each point in the image, i.e., original image intensity and gradient. Also, for speeding up the 2D image registration, the hierarchical motion compensation algorithm is implemented by a multi-resolution framework. The proposed method has been evaluated on a database of 73 subjects by quantitatively measuring signal-to-noise (SNR) ratio. DSA embedded with proposed strategies demonstrates an improvement of 74.1% over conventional DSA in terms of SNR. Our system runs on Eigen's DSA workstation using C++ in Windows environment.

  13. Modelling temporal stability of EPI time series using magnitude images acquired with multi-channel receiver coils.

    Directory of Open Access Journals (Sweden)

    Chloe Hutton

    Full Text Available In 2001, Krueger and Glover introduced a model describing the temporal SNR (tSNR of an EPI time series as a function of image SNR (SNR(0. This model has been used to study physiological noise in fMRI, to optimize fMRI acquisition parameters, and to estimate maximum attainable tSNR for a given set of MR image acquisition and processing parameters. In its current form, this noise model requires the accurate estimation of image SNR. For multi-channel receiver coils, this is not straightforward because it requires export and reconstruction of large amounts of k-space raw data and detailed, custom-made image reconstruction methods. Here we present a simple extension to the model that allows characterization of the temporal noise properties of EPI time series acquired with multi-channel receiver coils, and reconstructed with standard root-sum-of-squares combination, without the need for raw data or custom-made image reconstruction. The proposed extended model includes an additional parameter κ which reflects the impact of noise correlations between receiver channels on the data and scales an apparent image SNR (SNR'(0 measured directly from root-sum-of-squares reconstructed magnitude images so that κ = SNR'(0/SNR(0 (under the condition of SNR(0>50 and number of channels ≤32. Using Monte Carlo simulations we show that the extended model parameters can be estimated with high accuracy. The estimation of the parameter κ was validated using an independent measure of the actual SNR(0 for non-accelerated phantom data acquired at 3T with a 32-channel receiver coil. We also demonstrate that compared to the original model the extended model results in an improved fit to human task-free non-accelerated fMRI data acquired at 7T with a 24-channel receiver coil. In particular, the extended model improves the prediction of low to medium tSNR values and so can play an important role in the optimization of high-resolution fMRI experiments at lower SNR levels.

  14. Series of aerial images over Quivira National Wildlife Refuge, acquired October, 1938

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This data set is composite of original black and white series images obtained from Earth Explorer (USGS) on October 1st, 5th and 12th, 1938. The original photos...

  15. Series of aerial images over Quivira National Wildlife Refuge, acquired September, 1950

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This data set is composite of original black and white series images obtained from Earth Explorer (USGS) on September 23rd, 1950. The original photos were...

  16. ROPtool analysis of images acquired using a noncontact handheld fundus camera (Pictor)--a pilot study.

    Science.gov (United States)

    Vickers, Laura A; Freedman, Sharon F; Wallace, David K; Prakalapakorn, S Grace

    2015-12-01

    The presence of plus disease is the primary indication for treatment of retinopathy of prematurity (ROP), but its diagnosis is subjective and prone to error. ROPtool is a semiautomated computer program that quantifies vascular tortuosity and dilation. Pictor is an FDA-approved, noncontact, handheld digital fundus camera. This pilot study evaluated ROPtool's ability to analyze high-quality Pictor images of premature infants and its accuracy in diagnosing plus disease compared to clinical examination. In our small sample of images, ROPtool could trace and identify the presence of plus disease with high accuracy. PMID:26691046

  17. Three-dimensional imaging applications in Earth Sciences using video data acquired from an unmanned aerial vehicle

    Science.gov (United States)

    McLeod, Tara

    For three dimensional (3D) aerial images, unmanned aerial vehicles (UAVs) are cheaper to operate and easier to fly than the typical manned craft mounted with a laser scanner. This project explores the feasibility of using 2D video images acquired with a UAV and transforming them into 3D point clouds. The Aeryon Scout -- a quad-copter micro UAV -- flew two missions: the first at York University Keele campus and the second at the Canadian Wollastonite Mine Property. Neptec's ViDAR software was used to extract 3D information from the 2D video using structure from motion. The resulting point clouds were sparsely populated, yet captured vegetation well. They were used successfully to measure fracture orientation in rock walls. Any improvement in the video resolution would cascade through the processing and improve the overall results.

  18. Maximum-likelihood scintillation detection for EM-CCD based gamma cameras

    International Nuclear Information System (INIS)

    Gamma cameras based on charge-coupled devices (CCDs) coupled to continuous scintillation crystals can combine a good detection efficiency with high spatial resolutions with the aid of advanced scintillation detection algorithms. A previously developed analytical multi-scale algorithm (MSA) models the depth-dependent light distribution but does not take statistics into account. Here we present and validate a novel statistical maximum-likelihood algorithm (MLA) that combines a realistic light distribution model with an experimentally validated statistical model. The MLA was tested for an electron multiplying CCD optically coupled to CsI(Tl) scintillators of different thicknesses. For 99mTc imaging, the spatial resolution (for perpendicular and oblique incidence), energy resolution and signal-to-background counts ratio (SBR) obtained with the MLA were compared with those of the MSA. Compared to the MSA, the MLA improves the energy resolution by more than a factor of 1.6 and the SBR is enhanced by more than a factor of 1.3. For oblique incidence (approximately 450), the depth-of-interaction corrected spatial resolution is improved by a factor of at least 1.1, while for perpendicular incidence the MLA resolution does not consistently differ significantly from the MSA result for all tested scintillator thicknesses. For the thickest scintillator (3 mm, interaction probability 66% at 141 keV) a spatial resolution (perpendicular incidence) of 147 μm full width at half maximum (FWHM) was obtained with an energy resolution of 35.2% FWHM. These results of the MLA were achieved without prior calibration of scintillations as is needed for many statistical scintillation detection algorithms. We conclude that the MLA significantly improves the gamma camera performance compared to the MSA.

  19. Fast Orientation of Video Images of Buildings Acquired from a UAV without Stabilization.

    Science.gov (United States)

    Kedzierski, Michal; Delis, Paulina

    2016-06-23

    The aim of this research was to assess the possibility of conducting an absolute orientation procedure for video imagery, in which the external orientation for the first image was typical for aerial photogrammetry whereas the external orientation of the second was typical for terrestrial photogrammetry. Starting from the collinearity equations, assuming that the camera tilt angle is equal to 90°, a simplified mathematical model is proposed. The proposed method can be used to determine the X, Y, Z coordinates of points based on a set of collinearity equations of a pair of images. The use of simplified collinearity equations can considerably shorten the processing tine of image data from Unmanned Aerial Vehicles (UAVs), especially in low cost systems. The conducted experiments have shown that it is possible to carry out a complete photogrammetric project of an architectural structure using a camera tilted 85°-90° ( φ or ω) and simplified collinearity equations. It is also concluded that there is a correlation between the speed of the UAV and the discrepancy between the established and actual camera tilt angles.

  20. Acquiring Multiview C-Arm Images to Assist Cardiac Ablation Procedures

    Directory of Open Access Journals (Sweden)

    Pascal Fallavollita

    2010-01-01

    Full Text Available CARTO XP is an electroanatomical cardiac mapping system that provides 3D color-coded maps of the electrical activity of the heart; however it is expensive and it can only use a single costly magnetic catheter for each patient intervention. Our approach consists of integrating fluoroscopic and electrical data from the RF catheters into the same image so as to better guide RF ablation, shorten the duration of this procedure, increase its efficacy, and decrease hospital cost when compared to CARTO XP. We propose a method that relies on multi-view C-arm fluoroscopy image acquisition for (1 the 3D reconstruction of the anatomical structure of interest, (2 the robust temporal tracking of the tip-electrode of a mapping catheter between the diastolic and systolic phases and (3 the 2D/3D registration of color coded isochronal maps directly on the 2D fluoroscopy image that would help the clinician guide the ablation procedure much more effectively. The method has been tested on canine experimental data.

  1. Fast Orientation of Video Images of Buildings Acquired from a UAV without Stabilization

    Science.gov (United States)

    Kedzierski, Michal; Delis, Paulina

    2016-01-01

    The aim of this research was to assess the possibility of conducting an absolute orientation procedure for video imagery, in which the external orientation for the first image was typical for aerial photogrammetry whereas the external orientation of the second was typical for terrestrial photogrammetry. Starting from the collinearity equations, assuming that the camera tilt angle is equal to 90°, a simplified mathematical model is proposed. The proposed method can be used to determine the X, Y, Z coordinates of points based on a set of collinearity equations of a pair of images. The use of simplified collinearity equations can considerably shorten the processing tine of image data from Unmanned Aerial Vehicles (UAVs), especially in low cost systems. The conducted experiments have shown that it is possible to carry out a complete photogrammetric project of an architectural structure using a camera tilted 85°–90° (φ or ω) and simplified collinearity equations. It is also concluded that there is a correlation between the speed of the UAV and the discrepancy between the established and actual camera tilt angles. PMID:27347954

  2. Fast Orientation of Video Images of Buildings Acquired from a UAV without Stabilization

    Directory of Open Access Journals (Sweden)

    Michal Kedzierski

    2016-06-01

    Full Text Available The aim of this research was to assess the possibility of conducting an absolute orientation procedure for video imagery, in which the external orientation for the first image was typical for aerial photogrammetry whereas the external orientation of the second was typical for terrestrial photogrammetry. Starting from the collinearity equations, assuming that the camera tilt angle is equal to 90°, a simplified mathematical model is proposed. The proposed method can be used to determine the X, Y, Z coordinates of points based on a set of collinearity equations of a pair of images. The use of simplified collinearity equations can considerably shorten the processing tine of image data from Unmanned Aerial Vehicles (UAVs, especially in low cost systems. The conducted experiments have shown that it is possible to carry out a complete photogrammetric project of an architectural structure using a camera tilted 85°–90° ( φ or ω and simplified collinearity equations. It is also concluded that there is a correlation between the speed of the UAV and the discrepancy between the established and actual camera tilt angles.

  3. Fast Orientation of Video Images of Buildings Acquired from a UAV without Stabilization.

    Science.gov (United States)

    Kedzierski, Michal; Delis, Paulina

    2016-01-01

    The aim of this research was to assess the possibility of conducting an absolute orientation procedure for video imagery, in which the external orientation for the first image was typical for aerial photogrammetry whereas the external orientation of the second was typical for terrestrial photogrammetry. Starting from the collinearity equations, assuming that the camera tilt angle is equal to 90°, a simplified mathematical model is proposed. The proposed method can be used to determine the X, Y, Z coordinates of points based on a set of collinearity equations of a pair of images. The use of simplified collinearity equations can considerably shorten the processing tine of image data from Unmanned Aerial Vehicles (UAVs), especially in low cost systems. The conducted experiments have shown that it is possible to carry out a complete photogrammetric project of an architectural structure using a camera tilted 85°-90° ( φ or ω) and simplified collinearity equations. It is also concluded that there is a correlation between the speed of the UAV and the discrepancy between the established and actual camera tilt angles. PMID:27347954

  4. Acquiring a dataset of labeled video images showing discomfort in demented elderly.

    Science.gov (United States)

    Bonroy, Bert; Schiepers, Pieter; Leysens, Greet; Miljkovic, Dragana; Wils, Maartje; De Maesschalck, Lieven; Quanten, Stijn; Triau, Eric; Exadaktylos, Vasileios; Berckmans, Daniel; Vanrumste, Bart

    2009-05-01

    One of the effects of late-stage dementia is the loss of the ability to communicate verbally. Patients become unable to call for help if they feel uncomfortable. The first objective of this article was to record facial expressions of bedridden demented elderly. For this purpose, we developed a video acquisition system (ViAS) that records synchronized video coming from two cameras. Each camera delivers uncompressed color images of 1,024 x 768 pixels, up to 30 frames per second. It is the first time that such a system has been placed in a patient's room. The second objective was to simultaneously label these video recordings with respect to discomfort expressions of the patients. Therefore, we developed a Digital Discomfort Labeling Tool (DDLT). This tool provides an easy-to-use software representation on a tablet PC of validated "paper" discomfort scales. With ViAS and DDLT, 80 different datasets were obtained of about 15 minutes of recordings. Approximately 80% of the recorded datasets delivered the labeled video recordings. The remainder were not usable due to under- or overexposed images and due to the patients being out of view as the system was not properly replaced after care. In one of 6 observed patients, nurses recognized a higher discomfort level that would not have been observed without the DDLT.

  5. Detection of blood-related signal from a series of fingerprint images acquired during an input action

    Science.gov (United States)

    Fujieda, Ichiro; Hori, Atsushi; Kurita, Masashi

    2007-09-01

    When a finger is pressed against a flat plate and deformed, blood inside the finger moves away from the deformed area. This causes the finger to change its appearance from reddish to white. As the finger leaves the plate, the blood comes back and it looks reddish again. We have proposed to use this color change to distinguish genuine fingers from artificial ones for un-attended fingerprint identification systems. This blood-related signal may reflect the stiffness of the peripheral blood vessels and therefore it may be correlated with some health conditions such as blood pressure. In experiments, we used a fingerprint sensor based on scattered light detection. Because the spectra of the light scattered by the deformed fingers showed large changes mostly in the green portion, an LED emitting at 525 nm at peak strength was used. First, we compared series of fingerprint images acquired during a normal input action and those obtained while a rubber band occluded the blood flow. The occluded finger required a larger force to exhibit a similar change for these pixel values than the finger without the rubber band. Second, we analyzed fingerprint images recorded by six volunteers. We defined some indices based on the pixel values of the fingerprint images and the pressure applied to the fingers. The correlation coefficient of one of such indices and the average blood pressure of the participants was 0.86. Although the number of the subjects is small, this initial result is encouraging.

  6. Pulmonary cryptococcosis in rheumatoid arthritis (RA) patients: Comparison of imaging characteristics among RA, acquired immunodeficiency syndrome, and immunocompetent patients

    Energy Technology Data Exchange (ETDEWEB)

    Yanagawa, Noriyo, E-mail: noriyo_yana@ybb.ne.jp [Departments of Radiology, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, 3-8-22, Honkomagome, Bunkyo-ku, Tokyo 113-8677 (Japan); Sakai, Fumikazu [Department of Diagnostic Radiology, Saitama Medical University International Medical Center, 1397-1 Yamane, Hidaka-shi, Saitama 350-1298 (Japan); Takemura, Tamiko [Department of Pathology, Japanese Red Cross Medical Center, 4-1-22 Hiroo, Shibuya-ku, Tokyo 150-8935 (Japan); Ishikawa, Satoru [Department of Respiratory Medicine, National Hospital Organization Chiba-East-Hospital, 673 Nitona-cho, Chuo-ku, Chiba-shi, Chiba 260-8712 (Japan); Takaki, Yasunobu [Departments of Radiology, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, 3-8-22, Honkomagome, Bunkyo-ku, Tokyo 113-8677 (Japan); Hishima, Tsunekazu [Department of Pathology, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, 3-8-22, Honkomagome, Bunkyo-ku, Tokyo 113-8677 (Japan); Kamata, Noriko [Departments of Radiology, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, 3-8-22, Honkomagome, Bunkyo-ku, Tokyo 113-8677 (Japan)

    2013-11-01

    Purpose: The imaging characteristics of cryptococcosis in rheumatoid arthritis (RA) patients were analyzed by comparing them with those of acquired immunodeficiency syndrome (AIDS) and immunocompetent patients, and the imaging findings were correlated with pathological findings. Methods: Two radiologists retrospectively compared the computed tomographic (CT) findings of 35 episodes of pulmonary cryptococcosis in 31 patients with 3 kinds of underlying states (10 RA, 12 AIDS, 13 immunocompetent), focusing on the nature, number, and distribution of lesions. The pathological findings of 18 patients (8 RA, 2 AIDS, 8 immunocompetent) were analyzed by two pathologists, and then correlated with imaging findings. Results: The frequencies of consolidation and ground glass attenuation (GGA) were significantly higher, and the frequency of peripheral distribution was significantly lower in the RA group than in the immunocompetent group. Peripheral distribution was less common and generalized distribution was more frequent in the RA group than in the AIDS group. The pathological findings of the AIDS and immunocompetent groups reflected their immune status: There was lack of a granuloma reaction in the AIDS group, and a complete granuloma reaction in the immunocompetent group, while the findings of the RA group varied, including a complete granuloma reaction, a loose granuloma reaction and a hyper-immune reaction. Cases with the last two pathologic findings were symptomatic and showed generalized or central distribution on CT. Conclusion: Cryptococcosis in the RA group showed characteristic radiological and pathological findings compared with the other 2 groups.

  7. Pulmonary cryptococcosis in rheumatoid arthritis (RA) patients: Comparison of imaging characteristics among RA, acquired immunodeficiency syndrome, and immunocompetent patients

    International Nuclear Information System (INIS)

    Purpose: The imaging characteristics of cryptococcosis in rheumatoid arthritis (RA) patients were analyzed by comparing them with those of acquired immunodeficiency syndrome (AIDS) and immunocompetent patients, and the imaging findings were correlated with pathological findings. Methods: Two radiologists retrospectively compared the computed tomographic (CT) findings of 35 episodes of pulmonary cryptococcosis in 31 patients with 3 kinds of underlying states (10 RA, 12 AIDS, 13 immunocompetent), focusing on the nature, number, and distribution of lesions. The pathological findings of 18 patients (8 RA, 2 AIDS, 8 immunocompetent) were analyzed by two pathologists, and then correlated with imaging findings. Results: The frequencies of consolidation and ground glass attenuation (GGA) were significantly higher, and the frequency of peripheral distribution was significantly lower in the RA group than in the immunocompetent group. Peripheral distribution was less common and generalized distribution was more frequent in the RA group than in the AIDS group. The pathological findings of the AIDS and immunocompetent groups reflected their immune status: There was lack of a granuloma reaction in the AIDS group, and a complete granuloma reaction in the immunocompetent group, while the findings of the RA group varied, including a complete granuloma reaction, a loose granuloma reaction and a hyper-immune reaction. Cases with the last two pathologic findings were symptomatic and showed generalized or central distribution on CT. Conclusion: Cryptococcosis in the RA group showed characteristic radiological and pathological findings compared with the other 2 groups

  8. Practically acquired and modified cone-beam computed tomography images for accurate dose calculation in head and neck cancer

    Energy Technology Data Exchange (ETDEWEB)

    Hu, Chih-Chung [National Taiwan Univ. Hospital and College of Medicine, Taipei (China). Division of Radiation Oncology; Yuanpei Univ., Hsinchu (China). Dept. of Radiological Technology; Huang, Wen-Tao [Yuanpei Univ., Hsinchu (China). Dept. of Radiological Technology; Tsai, Chiao-Ling; Chao, Hsiao-Ling; Huang, Guo-Ming; Wang, Chun-Wei [National Taiwan Univ. Hospital and College of Medicine, Taipei (China). Division of Radiation Oncology; Wu, Jian-Kuen [National Taiwan Univ. Hospital and College of Medicine, Taipei (China). Division of Radiation Oncology; National Taiwan Normal Univ., Taipei (China). Inst. of Electro-Optical Science and Technology; Wu, Chien-Jang [National Taiwan Normal Univ., Taipei (China). Inst. of Electro-Optical Science and Technology; Cheng, Jason Chia-Hsien [National Taiwan Univ. Hospital and College of Medicine, Taipei (China). Division of Radiation Oncology; National Taiwan Univ. Taipei (China). Graduate Inst. of Oncology; National Taiwan Univ. Taipei (China). Graduate Inst. of Clinical Medicine; National Taiwan Univ. Taipei (China). Graduate Inst. of Biomedical Electronics and Bioinformatics

    2011-10-15

    On-line cone-beam computed tomography (CBCT) may be used to reconstruct the dose for geometric changes of patients and tumors during radiotherapy course. This study is to establish a practical method to modify the CBCT for accurate dose calculation in head and neck cancer. Fan-beam CT (FBCT) and Elekta's CBCT were used to acquire images. The CT numbers for different materials on CBCT were mathematically modified to match them with FBCT. Three phantoms were scanned by FBCT and CBCT for image uniformity, spatial resolution, and CT numbers, and to compare the dose distribution from orthogonal beams. A Rando phantom was scanned and planned with intensity-modulated radiation therapy (IMRT). Finally, two nasopharyngeal cancer patients treated with IMRT had their CBCT image sets calculated for dose comparison. With 360 acquisition of CBCT and high-resolution reconstruction, the uniformity of CT number distribution was improved and the otherwise large variations for background and high-density materials were reduced significantly. The dose difference between FBCT and CBCT was < 2% in phantoms. In the Rando phantom and the patients, the dose-volume histograms were similar. The corresponding isodose curves covering {>=} 90% of prescribed dose on FBCT and CBCT were close to each other (within 2 mm). Most dosimetric differences were from the setup errors related to the interval changes in body shape and tumor response. The specific CBCT acquisition, reconstruction, and CT number modification can generate accurate dose calculation for the potential use in adaptive radiotherapy.

  9. 3D reconstruction of hollow parts analyzing images acquired by a fiberscope

    International Nuclear Information System (INIS)

    A modified fiberscope used to reconstruct difficult-to-reach inner structures is presented. By substituting the fiberscope’s original illumination system, we can project a profile-revealing light line inside the object of study. The light line is obtained using a sandwiched power light-emitting diode (LED) attached to an extension arm on the tip of the fiberscope. Profile images from the interior of the object are then captured by a camera attached to the fiberscope’s eyepiece. Using a series of those images at different positions, the system is capable of generating a 3D reconstruction of the object with submillimeter accuracy. Also proposed is the use of a combination of known filters to remove the honeycomb structures produced by the fiberscope and the use of ring gages to obtain the extrinsic parameters of the camera attached to the fiberscope and the metrological traceability of the system. Several standard ring diameter measurements were compared against their certified values to improve the accuracy of the system. To exemplify an application, a 3D reconstruction of the interior of a refrigerator duct was conducted. This reconstruction includes accuracy assessment by comparing the measurements of the system to a coordinate measuring machine. The system, as described, is capable of 3D reconstruction of the interior of objects with uniform and non-uniform profiles from 10 to 60 mm in transversal dimensions and a depth of 1000 mm if the material of the walls of the object is translucent and allows the detection of the power LED light from the exterior through the wall. If this is not possible, we propose the use of a magnetic scale which reduces the working depth to 170 mm. The assessed accuracy is around ±0.15 mm in 2D cross-section reconstructions and ±1.3 mm in 1D position using a magnetic scale, and ±0.5 mm using a CCD camera. (paper)

  10. Use of Variogram Parameters in Analysis of Hyperspectral Imaging Data Acquired from Dual-Stressed Crop Leaves

    Directory of Open Access Journals (Sweden)

    Christian Nansen

    2012-01-01

    Full Text Available A detailed introduction to variogram analysis of reflectance data is provided, and variogram parameters (nugget, sill, and range values were examined as possible indicators of abiotic (irrigation regime and biotic (spider mite infestation stressors. Reflectance data was acquired from 2 maize hybrids (Zea mays L. at multiple time points in 2 data sets (229 hyperspectral images, and data from 160 individual spectral bands in the spectrum from 405 to 907 nm were analyzed. Based on 480 analyses of variance (160 spectral bands × 3 variogram parameters, it was seen that most of the combinations of spectral bands and variogram parameters were unsuitable as stress indicators mainly because of significant difference between the 2 data sets. However, several combinations of spectral bands and variogram parameters (especially nugget values could be considered unique indicators of either abiotic or biotic stress. Furthermore, nugget values at 683 and 775 nm responded significantly to abiotic stress, and nugget values at 731 nm and range values at 715 nm responded significantly to biotic stress. Based on qualitative characterization of actual hyperspectral images, it was seen that even subtle changes in spatial patterns of reflectance values can elicit several-fold changes in variogram parameters despite non-significant changes in average and median reflectance values and in width of 95% confidence limits. Such scattered stress expression is in accordance with documented within-leaf variation in both mineral content and chlorophyll concentration and therefore supports the need for reflectance-based stress detection at a high spatial resolution (many hyperspectral reflectance profiles acquired from a single leaf and may be used to explain or characterize within-leaf foraging patterns of herbivorous arthropods.

  11. Imaging of acquired non-traumatic cochlear lesions: iconographic essay; Avaliacao por imagem das lesoes cocleares adquiridas (nao-traumaticas): ensaio iconografico

    Energy Technology Data Exchange (ETDEWEB)

    Garcia, Marcelo de Mattos; Gonzaga, Juliana Gontijo [Clinica Axial - Centro de Imagem, Belo Horizonte, MG (Brazil)]. E-mail: cidbh@cidbh.com.br; marcelogarcia@superig.com.br

    2006-04-15

    Different non-traumatic acquired cochlear lesions are shown in this article with imaging methods. They may be responsible for neuro sensorial hearing loss or vertigo. The method of choice is computed tomography when evaluating the osseous labyrinth whereas magnetic resonance imaging has superior resolution in the studies of the membranaceous labyrinth. (author)

  12. Magnetic resonance imaging depiction of acquired Dyke-Davidoff-Masson syndrome with crossed cerebro-cerebellar diaschisis: Report of two cases

    Directory of Open Access Journals (Sweden)

    Ranjana Gupta

    2015-01-01

    Full Text Available Acquired Dyke-Davidoff-Masson syndrome, also known as hemispheric atrophy, is characterized by loss of volume of one cerebral hemisphere from an insult in early life. Crossed cerebellar diaschisis refers to dysfunction/atrophy of cerebellar hemisphere which is secondary to contralateral supratentorial insult. We describe magnetic resonance imaging findings in two cases of acquired Dyke-Davidoff-Masson syndrome with crossed cerebro-cerebellar diaschisis.

  13. Development of a single-shot CCD-based data acquisition system for time-resolved X-ray photoelectron spectroscopy at an X-ray free-electron laser facility

    International Nuclear Information System (INIS)

    A single-shot CCD-based data acquisition system for time-resolved photoelectron spectroscopy using an X-ray free-electron laser has been developed. The basic performance of the system is demonstrated using XFEL-induced and synchrotron-radiation-induced Ti 1s core-level spectroscopy. In order to utilize high-brilliance photon sources, such as X-ray free-electron lasers (XFELs), for advanced time-resolved photoelectron spectroscopy (TR-PES), a single-shot CCD-based data acquisition system combined with a high-resolution hemispherical electron energy analyzer has been developed. The system’s design enables it to be controlled by an external trigger signal for single-shot pump–probe-type TR-PES. The basic performance of the system is demonstrated with an offline test, followed by online core-level photoelectron and Auger electron spectroscopy in ‘single-shot image’, ‘shot-to-shot image (image-to-image storage or block storage)’ and ‘shot-to-shot sweep’ modes at soft X-ray undulator beamline BL17SU of SPring-8. In the offline test the typical repetition rate for image-to-image storage mode has been confirmed to be about 15 Hz using a conventional pulse-generator. The function for correcting the shot-to-shot intensity fluctuations of the exciting photon beam, an important requirement for the TR-PES experiments at FEL sources, has been successfully tested at BL17SU by measuring Au 4f photoelectrons with intentionally controlled photon flux. The system has also been applied to hard X-ray PES (HAXPES) in ‘ordinary sweep’ mode as well as shot-to-shot image mode at the 27 m-long undulator beamline BL19LXU of SPring-8 and also at the SACLA XFEL facility. The XFEL-induced Ti 1s core-level spectrum of La-doped SrTiO3 is reported as a function of incident power density. The Ti 1s core-level spectrum obtained at low power density is consistent with the spectrum obtained using the synchrotron source. At high power densities the Ti 1s core-level spectra show

  14. Investigation and identification of etiologies involved in the development of acquired hydronephrosis in aged laboratory mice with the use of high-frequency ultrasound imaging

    Directory of Open Access Journals (Sweden)

    Danielle A. Springer

    2014-08-01

    Full Text Available Laboratory mice develop naturally occurring lesions that affect biomedical research. Hydronephrosis is a recognized pathologic abnormality of the mouse kidney. Acquired hydronephrosis can affect any mouse, as it is caused by any naturally occurring disease that impairs free urine flow. Many etiologies leading to this condition are of particular significance to aging mice. Non-invasive ultrasound imaging detects renal pelvic dilation, renal enlargement, and parenchymal loss for pre-mortem identification of this condition. High-frequency ultrasound transducers produce high-resolution images of small structures, ideal for detecting organ pathology in mice. Using a 40 MHz linear array transducer, we obtained high-resolution images of a diversity of pathologic lesions occurring within the abdomen of seven geriatric mice with acquired hydronephrosis that enabled a determination of the underlying etiology. Etiologies diagnosed from the imaging results include pyelonephritis, neoplasia, urolithiasis, mouse urologic syndrome, and spontaneous hydronephrosis, and were confirmed at necropsy. A retrospective review of abdominal scans from an additional 149 aging mice shows that the most common etiologies associated with acquired hydronephrosis are mouse urologic syndrome and abdominal neoplasia. This report highlights the utility of high-frequency ultrasound for surveying research mice for age-related pathology, and is the first comprehensive report of multiple cases of acquired hydronephrosis in mice.

  15. Accurate IMRT fluence verification for prostate cancer patients using 'in-vivo' measured EPID images and in-room acquired kilovoltage cone-beam CT scans

    NARCIS (Netherlands)

    A.S.A.M. Ali (Ali Sid Ahmed M.); M.L.P. Dirkx (Maarten); R.M. Cools (Ruud); B.J.M. Heijmen (Ben)

    2013-01-01

    textabstractBackground: To investigate for prostate cancer patients the comparison of 'in-vivo' measured portal dose images (PDIs) with predictions based on a kilovoltage cone-beam CT scan (CBCT), acquired during the same treatment fraction, as an alternative for pre-treatment verification. For eval

  16. Acquired Techniques

    DEFF Research Database (Denmark)

    Lunde Nielsen, Espen; Halse, Karianne

    2013-01-01

    Acquired Techniques - a Leap into the Archive, at Aarhus School of Architecture. In collaboration with Karianne Halse, James Martin and Mika K. Friis. Following the footsteps of past travelers this is a journey into tools and techniques of the architectural process. The workshop will focus upon...

  17. Acquired blepharoptosis

    NARCIS (Netherlands)

    Oosterhuis, HJGH

    1996-01-01

    A review is given of the aetiology and possible treatment of acquired (non-congenital) blepharoptosis, which is a common but not specific sign of neurological disease: The diagnostic categories of upper eyelid drooping are scheduled as (a) pseudo-ptosis due to a local process or overactivity of eye

  18. Pixel Color Clustering of Multi-Temporally Acquired Digital Photographs of a Rice Canopy by Luminosity-Normalization and Pseudo-Red-Green-Blue Color Imaging

    Directory of Open Access Journals (Sweden)

    Ryoichi Doi

    2014-01-01

    Full Text Available Red-green-blue (RGB channels of RGB digital photographs were loaded with luminosity-adjusted R, G, and completely white grayscale images, respectively (RGwhtB method, or R, G, and R + G (RGB yellow grayscale images, respectively (RGrgbyB method, to adjust the brightness of the entire area of multi-temporally acquired color digital photographs of a rice canopy. From the RGwhtB or RGrgbyB pseudocolor image, cyan, magenta, CMYK yellow, black, L*, a*, and b* grayscale images were prepared. Using these grayscale images and R, G, and RGB yellow grayscale images, the luminosity-adjusted pixels of the canopy photographs were statistically clustered. With the RGrgbyB and the RGwhtB methods, seven and five major color clusters were given, respectively. The RGrgbyB method showed clear differences among three rice growth stages, and the vegetative stage was further divided into two substages. The RGwhtB method could not clearly discriminate between the second vegetative and midseason stages. The relative advantages of the RGrgbyB method were attributed to the R, G, B, magenta, yellow, L*, and a* grayscale images that contained richer information to show the colorimetrical differences among objects than those of the RGwhtB method. The comparison of rice canopy colors at different time points was enabled by the pseudocolor imaging method.

  19. Modelling temporal stability of EPI time series using magnitude images acquired with multi-channel receiver coils.

    OpenAIRE

    Chloe Hutton; Evelyne Balteau; Antoine Lutti; Oliver Josephs; Nikolaus Weiskopf

    2012-01-01

    In 2001, Krueger and Glover introduced a model describing the temporal SNR (tSNR) of an EPI time series as a function of image SNR (SNR(0)). This model has been used to study physiological noise in fMRI, to optimize fMRI acquisition parameters, and to estimate maximum attainable tSNR for a given set of MR image acquisition and processing parameters. In its current form, this noise model requires the accurate estimation of image SNR. For multi-channel receiver coils, this is not straightforwar...

  20. Development of a single-shot CCD-based data acquisition system for time-resolved X-ray photoelectron spectroscopy at an X-ray free-electron laser facility.

    Science.gov (United States)

    Oura, Masaki; Wagai, Tatsuya; Chainani, Ashish; Miyawaki, Jun; Sato, Hiromi; Matsunami, Masaharu; Eguchi, Ritsuko; Kiss, Takayuki; Yamaguchi, Takashi; Nakatani, Yasuhiro; Togashi, Tadashi; Katayama, Tetsuo; Ogawa, Kanade; Yabashi, Makina; Tanaka, Yoshihito; Kohmura, Yoshiki; Tamasaku, Kenji; Shin, Shik; Ishikawa, Tetsuya

    2014-01-01

    In order to utilize high-brilliance photon sources, such as X-ray free-electron lasers (XFELs), for advanced time-resolved photoelectron spectroscopy (TR-PES), a single-shot CCD-based data acquisition system combined with a high-resolution hemispherical electron energy analyzer has been developed. The system's design enables it to be controlled by an external trigger signal for single-shot pump-probe-type TR-PES. The basic performance of the system is demonstrated with an offline test, followed by online core-level photoelectron and Auger electron spectroscopy in 'single-shot image', 'shot-to-shot image (image-to-image storage or block storage)' and `shot-to-shot sweep' modes at soft X-ray undulator beamline BL17SU of SPring-8. In the offline test the typical repetition rate for image-to-image storage mode has been confirmed to be about 15 Hz using a conventional pulse-generator. The function for correcting the shot-to-shot intensity fluctuations of the exciting photon beam, an important requirement for the TR-PES experiments at FEL sources, has been successfully tested at BL17SU by measuring Au 4f photoelectrons with intentionally controlled photon flux. The system has also been applied to hard X-ray PES (HAXPES) in `ordinary sweep' mode as well as shot-to-shot image mode at the 27 m-long undulator beamline BL19LXU of SPring-8 and also at the SACLA XFEL facility. The XFEL-induced Ti 1s core-level spectrum of La-doped SrTiO3 is reported as a function of incident power density. The Ti 1s core-level spectrum obtained at low power density is consistent with the spectrum obtained using the synchrotron source. At high power densities the Ti 1s core-level spectra show space-charge effects which are analysed using a known mean-field model for ultrafast electron packet propagation. The results successfully confirm the capability of the present data acquisition system for carrying out the core-level HAXPES studies of condensed matter induced by the XFEL. PMID:24365935

  1. Development of a single-shot CCD-based data acquisition system for time-resolved X-ray photoelectron spectroscopy at an X-ray free-electron laser facility.

    Science.gov (United States)

    Oura, Masaki; Wagai, Tatsuya; Chainani, Ashish; Miyawaki, Jun; Sato, Hiromi; Matsunami, Masaharu; Eguchi, Ritsuko; Kiss, Takayuki; Yamaguchi, Takashi; Nakatani, Yasuhiro; Togashi, Tadashi; Katayama, Tetsuo; Ogawa, Kanade; Yabashi, Makina; Tanaka, Yoshihito; Kohmura, Yoshiki; Tamasaku, Kenji; Shin, Shik; Ishikawa, Tetsuya

    2014-01-01

    In order to utilize high-brilliance photon sources, such as X-ray free-electron lasers (XFELs), for advanced time-resolved photoelectron spectroscopy (TR-PES), a single-shot CCD-based data acquisition system combined with a high-resolution hemispherical electron energy analyzer has been developed. The system's design enables it to be controlled by an external trigger signal for single-shot pump-probe-type TR-PES. The basic performance of the system is demonstrated with an offline test, followed by online core-level photoelectron and Auger electron spectroscopy in 'single-shot image', 'shot-to-shot image (image-to-image storage or block storage)' and `shot-to-shot sweep' modes at soft X-ray undulator beamline BL17SU of SPring-8. In the offline test the typical repetition rate for image-to-image storage mode has been confirmed to be about 15 Hz using a conventional pulse-generator. The function for correcting the shot-to-shot intensity fluctuations of the exciting photon beam, an important requirement for the TR-PES experiments at FEL sources, has been successfully tested at BL17SU by measuring Au 4f photoelectrons with intentionally controlled photon flux. The system has also been applied to hard X-ray PES (HAXPES) in `ordinary sweep' mode as well as shot-to-shot image mode at the 27 m-long undulator beamline BL19LXU of SPring-8 and also at the SACLA XFEL facility. The XFEL-induced Ti 1s core-level spectrum of La-doped SrTiO3 is reported as a function of incident power density. The Ti 1s core-level spectrum obtained at low power density is consistent with the spectrum obtained using the synchrotron source. At high power densities the Ti 1s core-level spectra show space-charge effects which are analysed using a known mean-field model for ultrafast electron packet propagation. The results successfully confirm the capability of the present data acquisition system for carrying out the core-level HAXPES studies of condensed matter induced by the XFEL.

  2. Tumoral tracing and reconstruction of doses with images of MV acquired during treatment arco therapy volumetric; Seguimiento tumoral y reconstruccion de dosis con imagenes de MV adquiridas durante tratamientos de arcoterapia volumetrica

    Energy Technology Data Exchange (ETDEWEB)

    Azcona Armendariz, J. D.; Li, R.; Xing, L.

    2015-07-01

    Develop a strategy of tracking MV tumor on images acquired with flat panel and apply it to the characterization of the movement and dose reconstruction The research was conducted using a linear accelerator Varian True Beam, equipped with imaging system by Megavoltage. used images of patients with prostate cancer treated with volumetric arcotheraphy. (Author)

  3. Region-Based 3d Surface Reconstruction Using Images Acquired by Low-Cost Unmanned Aerial Systems

    Science.gov (United States)

    Lari, Z.; Al-Rawabdeh, A.; He, F.; Habib, A.; El-Sheimy, N.

    2015-08-01

    Accurate 3D surface reconstruction of our environment has become essential for an unlimited number of emerging applications. In the past few years, Unmanned Aerial Systems (UAS) are evolving as low-cost and flexible platforms for geospatial data collection that could meet the needs of aforementioned application and overcome limitations of traditional airborne and terrestrial mobile mapping systems. Due to their payload restrictions, these systems usually include consumer-grade imaging and positioning sensor which will negatively impact the quality of the collected geospatial data and reconstructed surfaces. Therefore, new surface reconstruction surfaces are needed to mitigate the impact of using low-cost sensors on the final products. To date, different approaches have been proposed to for 3D surface construction using overlapping images collected by imaging sensor mounted on moving platforms. In these approaches, 3D surfaces are mainly reconstructed based on dense matching techniques. However, generated 3D point clouds might not accurately represent the scanned surfaces due to point density variations and edge preservation problems. In order to resolve these problems, a new region-based 3D surface renostruction trchnique is introduced in this paper. This approach aims to generate a 3D photo-realistic model of individually scanned surfaces within the captured images. This approach is initiated by a Semi-Global dense Matching procedure is carried out to generate a 3D point cloud from the scanned area within the collected images. The generated point cloud is then segmented to extract individual planar surfaces. Finally, a novel region-based texturing technique is implemented for photorealistic reconstruction of the extracted planar surfaces. Experimental results using images collected by a camera mounted on a low-cost UAS demonstrate the feasibility of the proposed approach for photorealistic 3D surface reconstruction.

  4. REGION-BASED 3D SURFACE RECONSTRUCTION USING IMAGES ACQUIRED BY LOW-COST UNMANNED AERIAL SYSTEMS

    Directory of Open Access Journals (Sweden)

    Z. Lari

    2015-08-01

    Full Text Available Accurate 3D surface reconstruction of our environment has become essential for an unlimited number of emerging applications. In the past few years, Unmanned Aerial Systems (UAS are evolving as low-cost and flexible platforms for geospatial data collection that could meet the needs of aforementioned application and overcome limitations of traditional airborne and terrestrial mobile mapping systems. Due to their payload restrictions, these systems usually include consumer-grade imaging and positioning sensor which will negatively impact the quality of the collected geospatial data and reconstructed surfaces. Therefore, new surface reconstruction surfaces are needed to mitigate the impact of using low-cost sensors on the final products. To date, different approaches have been proposed to for 3D surface construction using overlapping images collected by imaging sensor mounted on moving platforms. In these approaches, 3D surfaces are mainly reconstructed based on dense matching techniques. However, generated 3D point clouds might not accurately represent the scanned surfaces due to point density variations and edge preservation problems. In order to resolve these problems, a new region-based 3D surface renostruction trchnique is introduced in this paper. This approach aims to generate a 3D photo-realistic model of individually scanned surfaces within the captured images. This approach is initiated by a Semi-Global dense Matching procedure is carried out to generate a 3D point cloud from the scanned area within the collected images. The generated point cloud is then segmented to extract individual planar surfaces. Finally, a novel region-based texturing technique is implemented for photorealistic reconstruction of the extracted planar surfaces. Experimental results using images collected by a camera mounted on a low-cost UAS demonstrate the feasibility of the proposed approach for photorealistic 3D surface reconstruction.

  5. First results for an image processing workflow for hyperspatial imagery acquired with a low-cost unmanned aerial vehicle (UAV).

    Science.gov (United States)

    Very high-resolution images from unmanned aerial vehicles (UAVs) have great potential for use in rangeland monitoring and assessment, because the imagery fills the gap between ground-based observations and remotely sensed imagery from aerial or satellite sensors. However, because UAV imagery is ofte...

  6. Simple luminosity normalization of greenness, yellowness and redness/greenness for comparison of leaf spectral profiles in multi-temporally acquired remote sensing images

    Indian Academy of Sciences (India)

    Ryoichi Doi

    2012-09-01

    Observation of leaf colour (spectral profiles) through remote sensing is an effective method of identifying the spatial distribution patterns of abnormalities in leaf colour, which enables appropriate plant management measures to be taken. However, because the brightness of remote sensing images varies with acquisition time, in the observation of leaf spectral profiles in multi-temporally acquired remote sensing images, changes in brightness must be taken into account. This study identified a simple luminosity normalization technique that enables leaf colours to be compared in remote sensing images over time. The intensity values of green and yellow (green+red) exhibited strong linear relationships with luminosity (R2 > 0.926) when various invariant rooftops in Bangkok or Tokyo were spectral-profiled using remote sensing images acquired at different time points. The values of the coefficient and constant or the coefficient of the formulae describing the intensity of green or yellow were comparable among the single Bangkok site and the two Tokyo sites, indicating the technique’s general applicability. For single rooftops, the values of the coefficient of variation for green, yellow, and red/green were 16% or less (n=6−11), indicating an accuracy not less than those of well-established remote sensing measures such as the normalized difference vegetation index. After obtaining the above linear relationships, raw intensity values were normalized and a temporal comparison of the spectral profiles of the canopies of evergreen and deciduous tree species in Tokyo was made to highlight the changes in the canopies’ spectral profiles. Future aspects of this technique are discussed herein.

  7. PET imaging of HSV1-tk mutants with acquired specificity toward pyrimidine- and acycloguanosine-based radiotracers

    Energy Technology Data Exchange (ETDEWEB)

    Likar, Yury; Dobrenkov, Konstantin; Olszewska, Malgorzata; Shenker, Larissa; Hricak, Hedvig; Ponomarev, Vladimir [Memorial Sloan-Kettering Cancer Center, Molecular Imaging Laboratory, Department of Radiology, New York, NY (United States); Cai, Shangde [Memorial Sloan-Kettering Cancer Center, Radiochemistry/Cyclotron Core Facility, New York, NY (United States)

    2009-08-15

    The aim of this study was to create an alternative mutant of the herpes simplex virus type 1 thymidine kinase (HSV1-tk) reporter gene with reduced phosphorylation capacity for acycloguanosine derivatives, but not pyrimidine-based compounds that will allow for successful PET imaging. A new mutant of HSV1-tk reporter gene, suitable for PET imaging using pyrimidine-based radiotracers, was developed. The HSV1-tk mutant contains an arginine-to-glutamine substitution at position 176 (HSV1-R176Qtk) of the nucleoside binding region of the enzyme. The mutant-gene product showed favorable enzymatic characteristics toward pyrimidine-based nucleosides, while exhibiting reduced activity with acycloguanosine derivatives. In order to enhance HSV1-R176Qtk reporter activity with pyrimidine-based radiotracers, we introduced the R176Q substitution into the more active HSV1-sr39tk mutant. U87 human glioma cells transduced with the HSV1-R176Qsr39tk double mutant reporter gene showed high {sup 3}H-FEAU pyrimidine nucleoside and low {sup 3}H-penciclovir acycloguanosine analog uptake in vitro. PET imaging also demonstrated high {sup 18}F-FEAU and low {sup 18}F-FHBG accumulation in HSV1-R176Qsr39tk+ xenografts. The feasibility of imaging two independent nucleoside-specific HSV1-tk mutants in the same animal with PET was demonstrated. Two opposite xenografts expressing the HSV1-R176Qsr39tk reporter gene and the previously described acycloguanosine-specific mutant of HSV1-tk, HSV1-A167Ysr39tk reporter gene, were imaged using a short-lived pyrimidine-based {sup 18}F-FEAU and an acycloguanosine-based {sup 18}F-FHBG radiotracer, respectively, administered on 2 consecutive days. We conclude that in combination with acycloguanosine-specific HSV1-A167Ysr39tk reporter gene, a HSV1-tk mutant containing the R176Q substitution could be used for PET imaging of two different cell populations or concurrent molecular biological processes in the same living subject. (orig.)

  8. PET imaging of HSV1-tk mutants with acquired specificity toward pyrimidine- and acycloguanosine-based radiotracers

    International Nuclear Information System (INIS)

    The aim of this study was to create an alternative mutant of the herpes simplex virus type 1 thymidine kinase (HSV1-tk) reporter gene with reduced phosphorylation capacity for acycloguanosine derivatives, but not pyrimidine-based compounds that will allow for successful PET imaging. A new mutant of HSV1-tk reporter gene, suitable for PET imaging using pyrimidine-based radiotracers, was developed. The HSV1-tk mutant contains an arginine-to-glutamine substitution at position 176 (HSV1-R176Qtk) of the nucleoside binding region of the enzyme. The mutant-gene product showed favorable enzymatic characteristics toward pyrimidine-based nucleosides, while exhibiting reduced activity with acycloguanosine derivatives. In order to enhance HSV1-R176Qtk reporter activity with pyrimidine-based radiotracers, we introduced the R176Q substitution into the more active HSV1-sr39tk mutant. U87 human glioma cells transduced with the HSV1-R176Qsr39tk double mutant reporter gene showed high 3H-FEAU pyrimidine nucleoside and low 3H-penciclovir acycloguanosine analog uptake in vitro. PET imaging also demonstrated high 18F-FEAU and low 18F-FHBG accumulation in HSV1-R176Qsr39tk+ xenografts. The feasibility of imaging two independent nucleoside-specific HSV1-tk mutants in the same animal with PET was demonstrated. Two opposite xenografts expressing the HSV1-R176Qsr39tk reporter gene and the previously described acycloguanosine-specific mutant of HSV1-tk, HSV1-A167Ysr39tk reporter gene, were imaged using a short-lived pyrimidine-based 18F-FEAU and an acycloguanosine-based 18F-FHBG radiotracer, respectively, administered on 2 consecutive days. We conclude that in combination with acycloguanosine-specific HSV1-A167Ysr39tk reporter gene, a HSV1-tk mutant containing the R176Q substitution could be used for PET imaging of two different cell populations or concurrent molecular biological processes in the same living subject. (orig.)

  9. Accurate IMRT fluence verification for prostate cancer patients using ‘in-vivo’ measured EPID images and in-room acquired kilovoltage cone-beam CT scans

    International Nuclear Information System (INIS)

    To investigate for prostate cancer patients the comparison of ‘in-vivo’ measured portal dose images (PDIs) with predictions based on a kilovoltage cone-beam CT scan (CBCT), acquired during the same treatment fraction, as an alternative for pre-treatment verification. For evaluation purposes, predictions were also performed using the patients’ planning CTs (pCT). To get reliable CBCT electron densities for PDI predictions, Hounsfield units from the pCT were mapped onto the CBCT, while accounting for non-rigidity in patient anatomy in an approximate way. PDI prediction accuracy was first validated for an anatomical phantom, using IMRT treatment plans of ten prostate cancer patients. Clinical performance was studied using data acquired for 50 prostate cancer patients. For each patient, 4–5 CBCTs were available, resulting in a total of 1413 evaluated images. Measured and predicted PDIs were compared using γ-analyses with 3% global dose difference and 3 mm distance to agreement as reference criteria. Moreover, the pass rate for automated PDI comparison was assessed. To quantify improvements in IMRT fluence verification accuracy results from multiple fractions were combined by generating a γ-image with values halfway the minimum and median γ values, pixel by pixel. For patients, CBCT-based PDI predictions showed a high agreement with measurements, with an average percentage of rejected pixels of 1.41% only. In spite of possible intra-fraction motion and anatomy changes, this was only slightly larger than for phantom measurements (0.86%). For pCT-based predictions, the agreement deteriorated (average percentage of rejected pixels 2.98%), due to an enhanced impact of anatomy variations. For predictions based on CBCT, combination of the first 2 fractions yielded gamma results in close agreement with pre-treatment analyses (average percentage of rejected pixels 0.63% versus 0.35%, percentage of rejected beams 0.6% versus 0%). For the pCT-based approach, only

  10. TU-C-12A-07: Characterization of Longitudinal Reproducibility of Quantitative Diffusion Imaging Data Acquired with Four Different Protocols Using a Phantom

    Energy Technology Data Exchange (ETDEWEB)

    Li, X [Georgia Regents University - Athens, Athens, Georgia (United States); Buzzelli, M; Randazzo, W; Yanasak, N [Georgia Regents University, Augusta, GA (Georgia)

    2014-06-15

    Purpose: To characterize and compare the longitudinal reproducibility of diffusion imaging data acquired with four different protocols using a phantom. Methods: The Diffusive Quantitative Imaging Phantom (DQIP) was constructed using fifteen cylindrical compartments within a larger compartment, filled with deionized water doped with CuSO4 and NaCl. The smaller compartments contained arrays of hexagonal or cylindrical glass capillaries of varying inner diameters, for differing restraint of water diffusion. The sensitivity of diffusion imaging metrics to signal-to-noise ratio (SNR) was probed by doping compartments with differing ratios of deuterium oxide to H2O. A cork phantom enclosure was constructed to increase thermal stability during scanning and a cork holder was made to reproduce scanner positioning. Four different protocols of DWI (diffusion weighted imaging) and DTI (Diffusion tensor imaging) imaging were assembled on a GE Excite HDx 3.0T MRI scanner to collect imaging data over 9-10 days. Data was processed with in-house software created in Matlab to obtain fractional anisotropy (FA) and apparent diffusion coefficient (ADC) values. Results: All DTI and DWI sequences showed good longitudinal stability of mean FA and ADC values per compartment, exhibiting low standard deviation ∼9%. A t-test was performed to compare mean FA values from the DTI clinical protocol to those of the DTI special protocol, indicating significantly different values in the majority of compartments. ANOVA performed on ADC values for all DTI and DWI sequences also showed significantly different values in a majority of compartments. Conclusion: This work has the potential for quantifying systemic variations between diffusion imaging sequences from different platforms. Characterization of DWI and DTI performance were done over four sequences with predictable results. This data suggests that the DQIP phantom may be a reliable method of monitoring day-to-day and scan-to-scan variation in

  11. Non-destructive assay employing 2D and 3D digital radiographic imaging acquired with thermal neutrons and reactor-produced radioisotopes

    International Nuclear Information System (INIS)

    The inner structure of some objects can only be visualized by using suitable techniques, when safety reasons or expensive costs preclude the application of invasive procedures. The kind of agent rendering an object partially transparent, unveiling thus its features, depends upon the object size and composition. As a rough rule of thumb, light materials are transparent to gamma and X-rays while the heavy ones are transparent to neutrons. When, after traversing an object, they hit a proper 2-D detector, a radiograph is produced representing a convoluted cross section, called projection, of that object. Taking a large number of such projections for different object attitudes, it is possible to obtain a 3-D tomography of the object as a map of attenuation coefficients. This procedure however, besides a time-consuming task, requires specially tailored equipment and software, not always available or affordable. Yet, in some circumstances it is feasible to replace the 3-D tomography by a stereoscopy, allowing one to visualize the spatial configuration of the object under analysis. In this work, 2-D and 3-D radiographic images have been acquired using thermal neutrons and reactor-produced radioisotopes and proper imaging plates as detectors. The stereographic vision has been achieved by taking two radiographs of the same object at different angles, from the detector point of view. After a treatment to render them red-white and green-white they were properly merged to yield a single image capable to be watched with red-green glasses. All the image treatment and rendering has been performed with the software ImageJ. (author)

  12. Clinical Evaluation of Spatial Accuracy of a Fusion Imaging Technique Combining Previously Acquired Computed Tomography and Real-Time Ultrasound for Imaging of Liver Metastases

    International Nuclear Information System (INIS)

    Purpose: This study was designed to evaluate the spatial accuracy of matching volumetric computed tomography (CT) data of hepatic metastases with real-time ultrasound (US) using a fusion imaging system (VNav) according to different clinical settings. Methods: Twenty-four patients with one hepatic tumor identified on enhanced CT and US were prospectively enrolled. A set of three landmarks markers was chosen on CT and US for image registration. US and CT images were then superimposed using the fusion imaging display mode. The difference in spatial location between the tumor visible on the CT and the US on the overlay images (reviewer no. 1, comment no. 2) was measured in the lateral, anterior–posterior, and vertical axis. The maximum difference (Dmax) was evaluated for different predictive factors.CT performed 1–30 days before registration versus immediately before. Use of general anesthesia for CT and US versus no anesthesia.Anatomic landmarks versus landmarks that include at least one nonanatomic structure, such as a cyst or a calcificationResultsOverall, Dmax was 11.53 ± 8.38 mm. Dmax was 6.55 ± 7.31 mm with CT performed immediately before VNav versus 17.4 ± 5.18 with CT performed 1–30 days before (p < 0.0001). Dmax was 7.05 ± 6.95 under general anesthesia and 16.81 ± 6.77 without anesthesia (p < 0.0015). Landmarks including at least one nonanatomic structure increase Dmax of 5.2 mm (p < 0.0001). The lowest Dmax (1.9 ± 1.4 mm) was obtained when CT and VNav were performed under general anesthesia, one immediately after the other. Conclusions: VNav is accurate when adequate clinical setup is carefully selected. Only under these conditions (reviewer no. 2), liver tumors not identified on US can be accurately targeted for biopsy or radiofrequency ablation using fusion imaging.

  13. Borehole-explosion and air-gun data acquired in the 2011 Salton Seismic Imaging Project (SSIP), southern California: description of the survey

    Science.gov (United States)

    Rose, Elizabeth J.; Fuis, Gary S.; Stock, Joann M.; Hole, John A.; Kell, Annie M.; Kent, Graham; Driscoll, Neal W.; Goldman, Mark; Reusch, Angela M.; Han, Liang; Sickler, Robert R.; Catchings, Rufus D.; Rymer, Michael J.; Criley, Coyn J.; Scheirer, Daniel S.; Skinner, Steven M.; Slayday-Criley, Coye J.; Murphy, Janice M.; Jensen, Edward G.; McClearn, Robert; Ferguson, Alex J.; Butcher, Lesley A.; Gardner, Max A.; Emmons, Iain; Loughran, Caleb L.; Svitek, Joseph R.; Bastien, Patrick C.; Cotton, Joseph A.; Croker, David S.; Harding, Alistair J.; Babcock, Jeffrey M.; Harder, Steven H.; Rosa, Carla M.

    2013-01-01

    earthquake energy can travel through the sediments. All of these factors determine how hard the earth will shake during a major earthquake. If we can improve on our understanding of how and where earthquakes will occur, and how strong their resultant shaking will be, then buildings can be designed or retrofitted accordingly in order to resist damage and collapse, and emergency plans can be adequately prepared. In addition, SSIP will investigate the processes of rifting and magmatism in the Salton Trough in order to better understand this important plate-boundary region. The Salton Trough is a unique rift in that subsidence is accompanied by huge influxes of infilling sediment from the Colorado River. Volcanism that accompanies the subsidence here is muted by these influxes of sediment. The Salton Trough, in the central part of the Imperial Valley, is apparently made up of entirely new crust: young sediment in the upper crust and basaltic intrusive rocks in the mid-to-lower crust (Fuis and others, 1984). Similar to the ultrasound and computed tomography (CT) scans performed by the medical industry, seismic imaging is a collection of techniques that enable scientists to obtain a picture of what is underground. The petroleum industry routinely uses these techniques to search for oil and gas at relatively shallow depths; however, the scope of this project demanded that we image as much as 30 km into the Earth’s crust. This project generated and recorded seismic waves, similar to sound waves, which move downward into the Earth and are bent (refracted) or echoed (reflected) back to the surface. SSIP acquired data in a series of intersecting lines that cover key areas of the Salton Trough. The sources of sound waves were detonations (shots) in deep boreholes, designed to create energy equivalent to magnitude 1–2 earthquakes. The study region routinely experiences earthquakes of these magnitudes, but earthquakes are not located in such a way as to permit us to create the

  14. Full-waveform inversion of multi-offset GPR data acquired in a vineyard to image and monitor soil water content

    Science.gov (United States)

    Lambot, Sébastien; André, Frédéric; Saussez, Stéphanie; van Durmen, Renaud; Delvaux, Bruno; van Leeuwen, Cornelis; Vereecken, Harry

    2010-05-01

    Sustainable and optimal agricultural and environmental management of water and land resources particularly relies on the description and understanding of soil water distribution and dynamics at the field scale. Knowledge of soil water content is essential in a vineyard, where it plays a crucial role in determining the wine quality through adequate water stresses. Yet, the inherent spatiotemporal variability of soil water content makes it difficult to assess at relevant scales and resolutions. In that respect, ground penetrating radar (GPR) has proven to be a useful geophysical tool to image the shallow subsurface and estimate its water content at the field scale. Traditional GPR techniques for soil water content estimation are usually based on strongly simplifying assumptions regarding electromagnetic wave propagation phenomena, which inherently leads to estimation errors and does not permit to account for the whole information content in the radar data. We developed a multi-offset full-waveform GPR model, which resorts to an exact solution of Maxwell's equations for wave propagating in multilayered media and a transfer function model describing the radar-antenna system and its interactions with the soil. The model is iteratively inverted using the global multilevel coordinate search algorithm to reconstruct the soil property profiles. The method was applied in a vineyard in south of France (Saint-Emilion) over an area of about 30 ha during summer 2009, resulting in about 1 million waveforms. The GPR system consisted in a time-domain GPR with two bistatic ground-coupled antennas, thereby resulting in two simultaneous offsets, with a center frequency of 400 MHz. Time-lapse measurements were also acquired after a precipitation event, and the data were inverted by coupling the GPR model to a soil hydrodynamic model. The results were consistent with field observations and electromagnetic induction measurements, thereby demonstrating the promising perspectives of the

  15. Clinical and imaging features of acquired hepatocerebrai degeneration%获得性肝性脑部变性的临床及影像学特点

    Institute of Scientific and Technical Information of China (English)

    黄小钦; 樊春秋; 贾建平

    2011-01-01

    Objective To investigate the clinical and imaging features of acquired hepatocerebral degeneration (AHCD). Methods The clinical data of 10 patients with AHCD were analyzed retrospectively. Results The age of the patients was 45 to 75 years old,the average age was (62.5 ± 10. I )years old. Course of the disease was 2 to 36 months,and the average course was ( 8.3 ± 3.2) months. Mean duration of the liver disease was 3 to 30 years.Clinical manifestation included psychiatric symptoms (7 cases), cognitive function impairment ( 5 cases), tremor ( 5 cases), involuntary movement ( 3 cases), dysarthria (4 cases) and ataxia ( 3 cases). M RI abnormalities were found in all the patients, including T1 WI high signal increased in globus pallidus (5 cases), lentiform nucleus (3 cases),putamen ( 1 case), caudate nucleus (4 cases ), cerebral peduncles ( 4 cases ), red nucleus ( 2 cases) and pontine ( 1 case) on T2 WI norraal signal ( 7 cases), slighty high signal ( 2 cases ), high signal ( 1 case) bilaterally. Conclusions The clinical features of AHCD are mental, cognitive and behavioral disorder and parkinsonism in patients with chronic liver disease. Imaging features are T1 WI high signal intensity on MRI in certain region ( such as bilateral basal ganglia and brain stem). MR1 examination may be helpful to diagnosis of AHCD.%目的 探讨获得性肝性脑部变性(AHCD)的临床及影像学特点.方法 回顾性分析10例AHCD患者的临床资料.结果 本组患者年龄45~75岁,平均(62.5±10.1)岁;病程2~36个月,平均(8.3±3.2)个月;有慢性肝病病史3~30年.临床表现为精神症状7例,认知功能障碍5例,震颤5例,不自主运动3例,构音障碍4例,共济失调3例.MRI均示有异常改变,表现为双侧苍白球(5例)、豆状核(3例)、壳核(1例)、尾状核(5例)、大脑脚(4例)、红核(2例)、脑桥(1例)部位对称性T1WI高信号,T2WI信号正常(7例)、稍高信号(2例)、高信号(1例).结论 AHCD的临床特点是慢性肝病

  16. Changes of Thermal Image in Epidural Anesthesia Acquired by Far-IR Thermal Imaging System%远红外热像仪采集硬膜外麻醉热像图变化的研究

    Institute of Scientific and Technical Information of China (English)

    马啸; 陈宁; 吕少文

    2012-01-01

    目的:应用红外热像技术监测硬膜外麻醉前、后热图变化.方法:选择下腹部手术患者,在(T12~L1)椎间隙行硬膜外穿刺置管,采集硬膜外单次注药后红外热像图.结果:硬膜外阻滞后5 min温度色码较麻醉前上移,红外热图色码平均温度较阻滞前有显著性差异(P<0.01),在神经平面(T12~L1)、(L4~L5、S1)区域温度色码在阻滞后5 min发生明显变化.结论:硬膜外阻滞后尤其L4~L5、S1所支配的神经平面色码变化非常显著,为以往的研究结果提供了更为直观的科学依据.%Objective To investigate the changes of the thermal images in epidural anesthesia by IR thermal imaging technology. Methods Some patients undergoing lower abdominal operation were selected as the subject, who went through epidural catheterization at T12-L1 intervertebral spaces. The IR thermal images after each epidural administration were acquired. Results The color code of temperature shifted up 5 minutes after the anesthesia, and there was significant difference for the color codes of the IR thermal images before and after the anesthesia, with P<0.01. The color codes of temperature in the area of (T12-L1) and (L4-L5, SI) increased obviously. Conclusion The color codes of temperature of infrared imaging after epidural anesthesia have great changes, especially in the area of foot (L4-L5 and S1 plane).

  17. Cardiovascular Magnetic Resonance Imaging in the Assessment of Myocardial Blood Flow, Viability, and Diffuse Fibrosis in Congenital and Acquired Heart Disease

    OpenAIRE

    Pham, Hoang Minh

    2014-01-01

    Myocardial ischemia may occur after surgical correction of congenital heart defects involving the coronary arteries, in patients with congenital coronary artery anomalies, or in acquired heart disease. To assess myocardial ischemia disease in children, we used cardiac MRI as a non-invasive and radiation-free method to evaluate myocardial perfusion, viability, diffuse myocardial fibrosis, and heart function, to guide further therapy and for a better understanding of the pathophysiology of the ...

  18. Point cloud generation from aerial image data acquired by a quadrocopter type micro unmanned aerial vehicle and a digital still camera.

    Science.gov (United States)

    Rosnell, Tomi; Honkavaara, Eija

    2012-01-01

    The objective of this investigation was to develop and investigate methods for point cloud generation by image matching using aerial image data collected by quadrocopter type micro unmanned aerial vehicle (UAV) imaging systems. Automatic generation of high-quality, dense point clouds from digital images by image matching is a recent, cutting-edge step forward in digital photogrammetric technology. The major components of the system for point cloud generation are a UAV imaging system, an image data collection process using high image overlaps, and post-processing with image orientation and point cloud generation. Two post-processing approaches were developed: one of the methods is based on Bae Systems' SOCET SET classical commercial photogrammetric software and another is built using Microsoft(®)'s Photosynth™ service available in the Internet. Empirical testing was carried out in two test areas. Photosynth processing showed that it is possible to orient the images and generate point clouds fully automatically without any a priori orientation information or interactive work. The photogrammetric processing line provided dense and accurate point clouds that followed the theoretical principles of photogrammetry, but also some artifacts were detected. The point clouds from the Photosynth processing were sparser and noisier, which is to a large extent due to the fact that the method is not optimized for dense point cloud generation. Careful photogrammetric processing with self-calibration is required to achieve the highest accuracy. Our results demonstrate the high performance potential of the approach and that with rigorous processing it is possible to reach results that are consistent with theory. We also point out several further research topics. Based on theoretical and empirical results, we give recommendations for properties of imaging sensor, data collection and processing of UAV image data to ensure accurate point cloud generation.

  19. Point cloud generation from aerial image data acquired by a quadrocopter type micro unmanned aerial vehicle and a digital still camera.

    Science.gov (United States)

    Rosnell, Tomi; Honkavaara, Eija

    2012-01-01

    The objective of this investigation was to develop and investigate methods for point cloud generation by image matching using aerial image data collected by quadrocopter type micro unmanned aerial vehicle (UAV) imaging systems. Automatic generation of high-quality, dense point clouds from digital images by image matching is a recent, cutting-edge step forward in digital photogrammetric technology. The major components of the system for point cloud generation are a UAV imaging system, an image data collection process using high image overlaps, and post-processing with image orientation and point cloud generation. Two post-processing approaches were developed: one of the methods is based on Bae Systems' SOCET SET classical commercial photogrammetric software and another is built using Microsoft(®)'s Photosynth™ service available in the Internet. Empirical testing was carried out in two test areas. Photosynth processing showed that it is possible to orient the images and generate point clouds fully automatically without any a priori orientation information or interactive work. The photogrammetric processing line provided dense and accurate point clouds that followed the theoretical principles of photogrammetry, but also some artifacts were detected. The point clouds from the Photosynth processing were sparser and noisier, which is to a large extent due to the fact that the method is not optimized for dense point cloud generation. Careful photogrammetric processing with self-calibration is required to achieve the highest accuracy. Our results demonstrate the high performance potential of the approach and that with rigorous processing it is possible to reach results that are consistent with theory. We also point out several further research topics. Based on theoretical and empirical results, we give recommendations for properties of imaging sensor, data collection and processing of UAV image data to ensure accurate point cloud generation. PMID:22368479

  20. Digital systems to acquire radiological imaging. Characteristics and quality control; Sistemas digitales de adquisicion de imagenes radiograficas. Caracteristicas y Control de Calidad

    Energy Technology Data Exchange (ETDEWEB)

    Torres Cabrera, R.; Hernando Gonzalez, I.

    2006-07-01

    Due to its special characteristics, quality control in digital radiographic systems is very important, even more than in conventional film-screen systems. Differences between digital and analogical images,a in terms of dynamics range, spatial and contrast resolution, and the flexibility of data post-processing require some actions to maintain clinical images in an optimum quality level. Revision 1 of the Spanish Protocol of Quality Control in Diagnostic Radiology includes a chapter dedicated to the quality control of these digital systems for the acquisition of radiographic images. In this paper the different parameters for quality control procedures are described. Also some difficulties to be concerned about (absence of levels of tolerance, access to the raw-data images and related information, availability of use anthropomorphic phantoms, etc, etc) are noted, as well as the most significant aspects of the differences in relation to the ana logical systems. (Author) 15 refs.

  1. Study of local cerebral hemodynamics by frequency-domain near-infrared spectroscopy and correlation with simultaneously acquired functional magnetic resonance imaging

    Science.gov (United States)

    Toronov, Vladislav; Webb, Andrew; Choi, Jee Hyun; Wolf, Martin; Safonova, Larisa; Wolf, Ursula; Gratton, Enrico

    2001-10-01

    The aim of our study was to explore the possibility of detecting hemodynamic changes in the brain using the phase of the intensity modulated optical signal. To obtain optical signals with the highest possible signal-to-noise ratio, we performed a series of simultaneous NIRS-fMRI measurements, with subsequent correlation of the time courses of both measurements. The cognitive paradigm used arithmetic calculations, with optical signals acquired with sensors placed on the forehead. Measurements were done on seven healthy subjects. In five subjects we demonstrated correlation between the hemodynamic signals obtained using NIRS and BOLD fMRI. In four subjects correlation was found for the hemodynamic signal obtained using the phase of the intensity modulated signal.

  2. Hospital-acquired pneumonia

    Science.gov (United States)

    ... tends to be more serious than other lung infections because: People in the hospital are often very sick and cannot fight off ... prevent pneumonia. Most hospitals have programs to prevent hospital-acquired infections.

  3. Acquired color vision deficiency.

    Science.gov (United States)

    Simunovic, Matthew P

    2016-01-01

    Acquired color vision deficiency occurs as the result of ocular, neurologic, or systemic disease. A wide array of conditions may affect color vision, ranging from diseases of the ocular media through to pathology of the visual cortex. Traditionally, acquired color vision deficiency is considered a separate entity from congenital color vision deficiency, although emerging clinical and molecular genetic data would suggest a degree of overlap. We review the pathophysiology of acquired color vision deficiency, the data on its prevalence, theories for the preponderance of acquired S-mechanism (or tritan) deficiency, and discuss tests of color vision. We also briefly review the types of color vision deficiencies encountered in ocular disease, with an emphasis placed on larger or more detailed clinical investigations.

  4. Laboratory-acquired brucellosis

    DEFF Research Database (Denmark)

    Fabiansen, C.; Knudsen, J.D.; Lebech, A.M.

    2008-01-01

    Brucellosis is a rare disease in Denmark. We describe one case of laboratory-acquired brucellosis from an index patient to a laboratory technician following exposure to an infected blood culture in a clinical microbiology laboratory Udgivelsesdato: 2008/6/9......Brucellosis is a rare disease in Denmark. We describe one case of laboratory-acquired brucellosis from an index patient to a laboratory technician following exposure to an infected blood culture in a clinical microbiology laboratory Udgivelsesdato: 2008/6/9...

  5. Contribution to the tracking and the 3D reconstruction of scenes composed of torus from image sequences a acquired by a moving camera

    International Nuclear Information System (INIS)

    The three-dimensional perception of the environment is often necessary for a robot to correctly perform its tasks. One solution, based on the dynamic vision, consists in analysing time-varying monocular images to estimate the spatial geometry of the scene. This thesis deals with the reconstruction of torus by dynamic vision. Though this object class is restrictive, it enables to tackle the problem of reconstruction of bent pipes usually encountered in industrial environments. The proposed method is based on the evolution of apparent contours of objects in the sequence. Using the expression of torus limb boundaries, it is possible to recursively estimate the object three-dimensional parameters by minimising the error between the predicted projected contours and the image contours. This process, which is performed by a Kalman filter, does not need a precise knowledge of the camera displacement or any matching of the tow limbs belonging to the same object. To complete this work, temporal tracking of objects which deals with occlusion situations is proposed. The approach consists in modeling and interpreting the apparent motion of objects in the successive images. The motion interpretation, based on a simplified representation of the scene, allows to recover pertinent three-dimensional information which is used to manage occlusion situations. Experiments, on synthetic and real images, proves he validity of the tracking and the reconstruction processes. (author)

  6. [Indication of neuro-imaging for the initial management and the follow-up of acute community-acquired bacterial meningitis].

    Science.gov (United States)

    Béquet, D; de Broucker, T

    2009-01-01

    Lumbar puncture is the best way to prove bacterial meningitis. It should be performed without any delay if the diagnosis is suspected. Herniation is a rare complication of LP. CT is normal in most cases of purulent meningitis, including those complicated by a subsequent herniation; normal CT results does not mean that performing a LP is safe. Three main clinical features can help determine which patient is at risk of herniation and should have a CT before LP. This risk has to be determined rapidly in the emergency ward while assessing anamnestic data, localization signs or symptoms, and level of consciousness. Cranial imaging (mainly MRI) is useful in the course of bacterial meningitis. Patients who do not respond well to treatment or with atypical presentation, persistence of fever, or new neurological signs should undergo brain imaging; MRI and CT may identify subdural effusions, brain abscesses, empyemas, hydrocephaly, or brain parenchymal changes (cerebritis, infarction, hemorrhage). CT and MRI are useful to screen for an ENT cause of bacterial meningitis, and mandatory in case of pneumococcal meningitis. Numerous MRI sequences are useful to identify bacterial meningitis complications: SE T1 without and with gadolinium injection, SE T2, FLAIR, gradient-echo T2, diffusion weighted imaging, MR angiography. PMID:19398288

  7. Etiopathology of acquired cholesteatoma

    Directory of Open Access Journals (Sweden)

    Prabodh Karnik

    2011-01-01

    Full Text Available The etiopathology of acquired cholesteatoma has undergone numerous changes over the past 150 years. However, certain facts stand out with clarity. The presence of cytokeratins in acquired cholesteatoma, which are akin to those found in the tympanic membrane and external auditory canal, shows that these are probably the site of origin of acquired cholesteatoma. The cholesteatoma sac also shows its greatest growth at its tympanic membrane attachment into the middle ear. Implantations of squamous epithelium due to trauma or surgery could be another originating factor. The basic pathology is the formation of papillary cones from the tympanic membrane or external auditory canal, which progress from microcholesteatoma to frank cholesteatoma with keratin collections. There is an altered matrix metalloproteinase pathway. Tumor necrosis factor activation with altered wound healing process contributes to the collateral destruction of bone. Trisomy and aneuploidy of chromosome 8 predispose to cholesteatoma formation in affected individuals. In this article, we present the etiopathology of acquired cholesteatoma as it stands today.

  8. "Ready to Acquire"

    DEFF Research Database (Denmark)

    Yetton, Philip; Henningsson, Stefan; Bjørn-Andersen, Niels

    2013-01-01

    This article describes the experiences of Danisco (a global food ingredients company) as it followed a growth-by-acquisition business strategy, focusing on how a new CIO built the IT resources to ensure the IT organization was "ready to acquire." We illustrate how these IT capabilities expedited...

  9. Spatial Co-Registration of Ultra-High Resolution Visible, Multispectral and Thermal Images Acquired with a Micro-UAV over Antarctic Moss Beds

    Directory of Open Access Journals (Sweden)

    Darren Turner

    2014-05-01

    Full Text Available In recent times, the use of Unmanned Aerial Vehicles (UAVs as tools for environmental remote sensing has become more commonplace. Compared to traditional airborne remote sensing, UAVs can provide finer spatial resolution data (up to 1 cm/pixel and higher temporal resolution data. For the purposes of vegetation monitoring, the use of multiple sensors such as near infrared and thermal infrared cameras are of benefit. Collecting data with multiple sensors, however, requires an accurate spatial co-registration of the various UAV image datasets. In this study, we used an Oktokopter UAV to investigate the physiological state of Antarctic moss ecosystems using three sensors: (i a visible camera (1 cm/pixel, (ii a 6 band multispectral camera (3 cm/pixel, and (iii a thermal infrared camera (10 cm/pixel. Imagery from each sensor was geo-referenced and mosaicked with a combination of commercially available software and our own algorithms based on the Scale Invariant Feature Transform (SIFT. The validation of the mosaic’s spatial co-registration revealed a mean root mean squared error (RMSE of 1.78 pixels. A thematic map of moss health, derived from the multispectral mosaic using a Modified Triangular Vegetation Index (MTVI2, and an indicative map of moss surface temperature were then combined to demonstrate sufficient accuracy of our co-registration methodology for UAV-based monitoring of Antarctic moss beds.

  10. Summary of results and conclusions based on analysis of volume imaging and high spectral resolution lidar data acquired during FIRE phase 1, part 1

    Science.gov (United States)

    Grund, Christian J.; Eloranta, E. W.

    1990-01-01

    The collection of long term global statistics on cloud cover may be most easily accomplished with satellite based observations; however, measurements derived from passive satellite retrieval methods must be calibrated and verified by in situ or ground based remote sensor observations. Verification is not straight forward, however, because the highly variable nature of cloud altitude, morphology, and optical characteristics complicates the scaling of point measurements to satellite footprint sized areas. This is particularly evident for cirrus clouds which may be organized on horizontal scales of 10's of meters to 8 km or more, and have optical depths ranging from less than .003 to greater than 3. Cirrus clouds can strongly influence earths' radiative balance, but, because they are often transmissive, cirrus clouds are difficult to detect and characterize from satellite measurements. Because of its precise ranging capabilities, spatial resolution and sensitivity, lidar observations have played an important role in the detection, depiction, and characterization of cirrus clouds. Some of the characteristics of cirrus clouds are summarized which observed the High Spectral Resolution and Volume Imaging Lidars during the phase 1 IFO and ETO periods.

  11. Combined Spectral and Spatial Modeling of Corn Yield Based on Aerial Images and Crop Surface Models Acquired with an Unmanned Aircraft System

    Directory of Open Access Journals (Sweden)

    Jakob Geipel

    2014-10-01

    Full Text Available Precision Farming (PF management strategies are commonly based on estimations of within-field yield potential, often derived from remotely-sensed products, e.g., Vegetation Index (VI maps. These well-established means, however, lack important information, like crop height. Combinations of VI-maps and detailed 3D Crop Surface Models (CSMs enable advanced methods for crop yield prediction. This work utilizes an Unmanned Aircraft System (UAS to capture standard RGB imagery datasets for corn grain yield prediction at three early- to mid-season growth stages. The imagery is processed into simple VI-orthoimages for crop/non-crop classification and 3D CSMs for crop height determination at different spatial resolutions. Three linear regression models are tested on their prediction ability using site-specific (i unclassified mean heights, (ii crop-classified mean heights and (iii a combination of crop-classified mean heights with according crop coverages. The models show determination coefficients \\({R}^{2}\\ of up to 0.74, whereas model (iii performs best with imagery captured at the end of stem elongation and intermediate spatial resolution (0.04m\\(\\cdot\\px\\(^{-1}\\.Following these results, combined spectral and spatial modeling, based on aerial images and CSMs, proves to be a suitable method for mid-season corn yield prediction.

  12. AIDS: acquired immunodeficiency syndrome

    OpenAIRE

    Gilmore, N. J.; Beaulieu, R.; Steben, M.; Laverdière, M.

    2002-01-01

    Acquired immunodeficiency syndrome, or AIDS, is a new illness that occurs in previously healthy individuals. It is characterized by immunodeficiency, opportunistic infections and unusual malignant diseases. Life-threatening single or multiple infections with viruses, mycobacteria, fungi or protozoa are common. A rare neoplasm, Kaposi's sarcoma, has developed in approximately one third of patients with AIDS. More than 800 cases of AIDS have been reported in North America, over 24 of them in Ca...

  13. Acquired hypertrichosis lanuginosa

    Directory of Open Access Journals (Sweden)

    Kumar Pramod

    1993-01-01

    Full Text Available Acquired hypertirichosis lanuginose developed rapidly in a patient with no detectable malignancy. Soft, fine, downy hair growth was noticed on the face, ears, limbs and trunk. Bilaterally symmetrical vitiliginous macules were present on the ear and preauricular region. This case is reported because of its rarity, absence of any detectable malignancy and development of vitiligo, which to our knowledge has not been reported earlier.

  14. Acquired von Willebrand Syndrome

    Institute of Scientific and Technical Information of China (English)

    郭涛

    2005-01-01

    @@ Acquired von Willebrand syndrome (AvWS) is kind of bleeding disorder with laboratory findings similar to those in congenital yon Willebrand disease (vWD).AvWS doesn's have any personal or family history of bleeding, but is associated with certain diseases or abnormal conditions or drugs. Although AvWS is being stated as a rare disease, it has gained more and more attention during the past years. Not because of the severity of the disease, but it is more common than we thought and most patients don' t have a proper diagnosis.

  15. Acquired epidermolysis bullosa

    Directory of Open Access Journals (Sweden)

    Maricel Sucar Batista

    2015-12-01

    Full Text Available Epidermolysis bullosa is a group of diseases or skin disorders genetically transmitted and it is characterized by the appearance of bullae, ulcers and skin wounds. It usually appears at birth or in the first months of life. This is a case of a 72-year-old female patient who comes to the dermatology department with skin lesions of 6 months of evolution. A skin biopsy was performed, taking a sample for direct and indirect immunofluorescence. Acquired epidermolysis bullosa of unknown etiology was diagnosed. Treatment was started with low-dose colchicine to increase it later, according to the patient’s tolerance and disease progression.

  16. Engineering Study on the CCD-based Measurement of Pulse Laser far-field Divergence Angle%基于CCD的脉冲激光器远场发散角工程化研究

    Institute of Scientific and Technical Information of China (English)

    邢勇; 邢冀川; 宋艳

    2011-01-01

    简述了激光光束的基本参数及特性,并介绍了采用CCD进行激光发散角测量的基本原理和装置.用CCD测量光斑可以及时获得光斑的二维扫描结果.实际工程应用时常采用CCD来测量激光远场发散角.进一步介绍了使用CCD摄像法进行发散角测量所采用的系统软件设计,首次提出了采用图像处理的方法来捕捉脉冲激光光斑.%This paper demonstrated the basic parameters and characteristics of laser beam, and introduced the basic principles and the devices used in the CCD laser divergence angle measurement method. Using CCD to measure the beam spot can gain the two-dimensional scanned result in a real-time manager. As a result, CCD was always used to measure Far-field divergence angle of the laser beam in the real engineering applications. The paper also made a further introduction of software design in the measuring system using CCD camera method. Finally, it is the first time that by the image-processing method to acquire pulse laser spot is introduced.

  17. Psychological issues in acquired facial trauma

    Directory of Open Access Journals (Sweden)

    De Sousa Avinash

    2010-01-01

    Full Text Available The face is a vital component of one′s personality and body image. There are a vast number of variables that influence recovery and rehabilitation from acquired facial trauma many of which are psychological in nature. The present paper presents the various psychological issues one comes across in facial trauma patients. These may range from body image issues to post-traumatic stress disorder symptoms accompanied by anxiety and depression. Issues related to facial and body image affecting social life and general quality of life are vital and the plastic surgeon should be aware of such issues and competent to deal with them in patients and families.

  18. Acquired Blaschkoid dermatitis

    Directory of Open Access Journals (Sweden)

    Mercy P

    2007-01-01

    Full Text Available Acquired Blaschkoid dermatitis characterised by unilateral relapsing inflammatory disease along the lines of Blaschko. A 40-year-old Indian male presented with unilateral erythematous, itchy grouped papules on the left side of the chest, abdomen, back and left arm of 15 days duration. The eruption stopped abruptly at the midline of the torso, completely sparing the right side of the body. The lesions were arranged in whorls and streaks corresponding to the lines of Blaschko. Skin biopsy showed hyperkeratosis and features suggestive of sub-acute spongiotic dermatitis with lymphocytic infiltrate around the blood vessels in the dermis. Patient was diagnosed as a case of Blaschkoid dermatitis. To the best of our knowledge, this is the first case of this condition being reported from India.

  19. Learning-By-Being-Acquired

    DEFF Research Database (Denmark)

    Colombo, Massimo G.; Moreira, Solon; Rabbiosi, Larissa

    In this paper we study post-acquisition integration in terms of R&D team reorganization—i.e., the creation of new teams with both inventors of the acquiring and acquired firms—and assess its impact on knowledge transfer in the period that follows the acquisition. Drawing on social identity and self......-categorization theories, we argue that R&D team reorganization increases the acquired inventors’ use of the prior stock of technological knowledge of the acquiring firm after the acquisition. Furthermore, this effect is enhanced if acquired inventors have higher innovation ability relative to their acquiring peers...... but is weakened for acquired inventors with high preacquisition ingroup collaborative strength. We construct a sample of 3,625 acquired inventors implementing the coarsened exact matching (CEM) technique and empirically test our arguments applying a difference-in-differences setup in a longitudinal data setting...

  20. 获得性肝性脑部变性的影像学诊断及临床分析%Imaging diagnosis and clinical analysis of acquired hepatocerebral degeneration

    Institute of Scientific and Technical Information of China (English)

    楼晓剑; 蒋定尧; 俞高龙

    2012-01-01

    Objective To evaluate CT an MR imaging findings of acquired hepatocerebral degeneration (AHCD). Methods Twenty cases with AHCD diagnosed by clinic, CT, MRI and corifirmed by follow-up were retrospectively analyzed. 10/20 cases underwent abdominal MR or CT scan simultaneously. Results Among the 20 cases, the abnormalities found by MR imaging were mainly symmetrical high signals in basal ganglia and brain stem, including globus pallidus in 19, putamen in 3, caudate nucleus in 5, surroundings of mcsoccrcbrum and red nucleus in 15,cerebral peduncles in 5, pontinc in 3 and anterior pituitary in 8 cases on T1WI. Normal signal in 12, slighty high signal in 6, high signal in 2 on T2WI and normal signal in 1 5 , high signal in 5 cases on DWI were detected. Conclusion In AHCD, hypcrintense on T1 WI in certain rcgion(such as bilateral basal ganglia and brain stem) is the characteristic imaging finding, which is sensitive to detect by MR imaging,most cases of AHCD can be diagnosed correctly according to the MRI characteristic findings.%目的 研究获得性肝性脑部变性(AHCD)的CT和MRI表现.方法对20例经临床、CT和MRI诊断后随访确诊的病例进行分析,其中10例同时行腹部MRI或CT扫描.结果 20例 AHCD中,MRI均示有异常改变:主要显示基底节及脑干区快速自旋回波(TSE)T1WI对称性高信号,其中双侧苍白球19例,壳3例,尾状核5例,中脑红核周围15例,大脑脚5例、脑桥3例,垂体前叶8例.TSE T2WI信号正常12例,稍高信号6例,高信号2例,扩散加权信号正常15例,高信号5例.结论 MRI T1WI双侧基底节及中脑等部位出现高信号影,是AHCD较为特征性的影像学表现,MRI是发现这些病变最敏感的方法.结合临床病史,绝大部分病例可明确诊断.

  1. Intercontrole acquiring by Framatome

    International Nuclear Information System (INIS)

    The Framatome group, as the worldwide leader in nuclear power plant construction, has reinforced his competences in nuclear services thanks to the acquiring of the Intercontrole company, specialized in non-destructive testing in nuclear and industrial environments. After a presentation of the functioning principle and of the safety aspects of a PWR reactor, this press dossier presents in a first part the role of nuclear services and in particular of non-destructive testing in nuclear power plants (in-service inspection, regulatory aspects, testing processes). This part is illustrated with some examples of inspection performed on some components of the primary coolant loop (steam generators, reactor vessel, pressurizer, pipes, primary pumps). A second part presents the technical centres and units of Framatome in charge of performing non-destructive inspections, while a third part describes the industrial policy and strategy of the group in this domain (market of nuclear park maintenance in France, in the USA and worldwide, creation of the 'inspection and control' centre of Framatome). A last part presents the activities of the Intercontrole company and of its daughter companies with some examples of actions realized in the nuclear and natural gas domains. (J.S.)

  2. Earth Knowledge Acquired by Middle School Students

    Science.gov (United States)

    Ride, Sally

    2008-01-01

    Earth Knowledge Acquired by Middle School Students (EarthKAM), an education activity, allows middle school students to program a digital camera on board the International Space Station to photograph a variety of geographical targets for study in the classroom. Photos are made available on the web for viewing and study by participating schools around the world. Educators use the images for projects involving Earth Science, geography, physics, and social science.

  3. Analysis of the Imaging Speed of the CCD Based Neutron Digital Radiography System%基于CCD的中子数字照相系统成像速度分析

    Institute of Scientific and Technical Information of China (English)

    唐彬; 李西安; 霍合勇; 薛斌

    2007-01-01

    成像速度是中子冷阴极放电器(CCD)数字照相系统的主要性能参数.根据中子数字照相的原理、光学成像的基本关系式和CCD的特性,提出了一种基于CCD的中子数字照相系统的成像速度理论推算方法,对SPRR-300中子数字照相系统成像速度进行了计算,并与试验结果相比较证明,理论计算与试验基本吻合,计算方法可信.

  4. Pathology of the thoracic wall: congenital and acquired

    Energy Technology Data Exchange (ETDEWEB)

    Garcia-Pena, Pilar; Barber, Ignasi [Hospital Materno-Infantil, Pediatric Radiology, Barcelona (Spain)

    2010-06-15

    This review aims to cover the main congenital and acquired lesions that arise in the thoracic wall of infants and children. Imaging often plays an essential role in the evaluation of symptomatic and asymptomatic thoracic wall abnormalities. The use of appropriate imaging modalities for each condition will be addressed, as well as the range of benign and malignant conditions that can occur. (orig.)

  5. Acquired ichthyosis with hoffman's syndrome

    Directory of Open Access Journals (Sweden)

    Sathyanarayana B

    2003-01-01

    Full Text Available A middle aged man presented with features of acquired ichthyosis with Hoffman's syndrome. Laboratory tests support hypothyodism. Myoedema and hypertrophy of muscles were present. Patient was previously treated for Pellagra.

  6. Somatically acquired structural genetic differences

    DEFF Research Database (Denmark)

    Magaard Koldby, Kristina; Nygaard, Marianne; Christensen, Kaare;

    2016-01-01

    Structural genetic variants like copy number variants (CNVs) comprise a large part of human genetic variation and may be inherited as well as somatically acquired. Recent studies have reported the presence of somatically acquired structural variants in the human genome and it has been suggested...... with age.European Journal of Human Genetics advance online publication, 20 April 2016; doi:10.1038/ejhg.2016.34....

  7. Sigmoid plate dehiscence: Congenital or acquired condition?

    International Nuclear Information System (INIS)

    Highlights: • CT with multiplanar reformations can accurately display the sigmoid platet dehiscence. • The prevalence of sigmoid plate dehiscence was no significant difference among different age groups. • The size of sigmoid plate bony defects were not statistically different among different age groups. • The sigmoid plate dehiscence is more commonly a congenital than an acquired condition. - Abstract: Background and purpose: The imaging features of sigmoid plate dehiscence-induced pulsatile tinnitus have been presented. The origin of the sigmoid plate dehiscence, however, remains unclear. Our aim was to assess the prevalence and extent of sigmoid plate dehiscence on computed tomography (CT) images in multiple age groups to determine whether this condition is more likely to be congenital or acquired. Materials and methods: We retrospectively reviewed contrast-enhanced CT images of sigmoid plates of temporal bones in 504 patients. Each temporal bone was characterized as normal or dehiscent. Patients were then subcategorized into four age groups, and the prevalence and extent of dehiscent sigmoid plates in each group were calculated and compared. Results: Overall, 80 patients had sigmoid plate dehiscence, nine of whom had it bilaterally. In successively older age groups, the prevalences of sigmoid plate dehiscence were 18.9%, 20.1%, 14.5%, and 12.7%, respectively. Respective average anteroposterior bony defect diameters were 3.7 ± 1.7, 3.0 ± 1.3, 3.1 ± 1.5, and 3.0 ± 1.1 mm. Respective average vertical bony defect diameters were 3.6 ± 2.3, 2.6 ± 1.2, 3.2 ± 1.5, and 3.0 ± 1.7 mm. The prevalence and extent of sigmoid plate dehiscence were not statistically different among the four age groups. Conclusions: The similar radiologic prevalence and extent of dehiscent sigmoid plates among the age groups suggest that the dehiscence is more commonly a congenital than an acquired condition

  8. Sigmoid plate dehiscence: Congenital or acquired condition?

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Zhaohui, E-mail: lzhtrhos@163.com [Capital Medical University, Beijing Tongren Hospital, No 1 Dong Jiao Min Street, Dongcheng District, Beijing 100730 (China); Li, Jing, E-mail: lijingxbh@yahoo.com.cn [Capital Medical University, Beijing Tongren Hospital, No 1 Dong Jiao Min Street, Dongcheng District, Beijing 100730 (China); Zhao, Pengfei, E-mail: zhaopengf05@163.com [Capital Medical University, Beijing Friendship Hospital, No 95 Yongan Road, Xicheng District, Beijing 100050 (China); Lv, Han, E-mail: chrislvhan@126.com [Capital Medical University, Beijing Friendship Hospital, No 95 Yongan Road, Xicheng District, Beijing 100050 (China); Dong, Cheng, E-mail: derc007@sina.com [Capital Medical University, Beijing Friendship Hospital, No 95 Yongan Road, Xicheng District, Beijing 100050 (China); Liu, Wenjuan, E-mail: wenjuanliu@163.com [Jining No. 1 People' s Hospital, No. 6 Health Street, Jining 272100 (China); Wang, Zhenchang, E-mail: cjr.wzhch@vip.163.com [Capital Medical University, Beijing Friendship Hospital, No 95 Yongan Road, Xicheng District, Beijing 100050 (China)

    2015-05-15

    Highlights: • CT with multiplanar reformations can accurately display the sigmoid platet dehiscence. • The prevalence of sigmoid plate dehiscence was no significant difference among different age groups. • The size of sigmoid plate bony defects were not statistically different among different age groups. • The sigmoid plate dehiscence is more commonly a congenital than an acquired condition. - Abstract: Background and purpose: The imaging features of sigmoid plate dehiscence-induced pulsatile tinnitus have been presented. The origin of the sigmoid plate dehiscence, however, remains unclear. Our aim was to assess the prevalence and extent of sigmoid plate dehiscence on computed tomography (CT) images in multiple age groups to determine whether this condition is more likely to be congenital or acquired. Materials and methods: We retrospectively reviewed contrast-enhanced CT images of sigmoid plates of temporal bones in 504 patients. Each temporal bone was characterized as normal or dehiscent. Patients were then subcategorized into four age groups, and the prevalence and extent of dehiscent sigmoid plates in each group were calculated and compared. Results: Overall, 80 patients had sigmoid plate dehiscence, nine of whom had it bilaterally. In successively older age groups, the prevalences of sigmoid plate dehiscence were 18.9%, 20.1%, 14.5%, and 12.7%, respectively. Respective average anteroposterior bony defect diameters were 3.7 ± 1.7, 3.0 ± 1.3, 3.1 ± 1.5, and 3.0 ± 1.1 mm. Respective average vertical bony defect diameters were 3.6 ± 2.3, 2.6 ± 1.2, 3.2 ± 1.5, and 3.0 ± 1.7 mm. The prevalence and extent of sigmoid plate dehiscence were not statistically different among the four age groups. Conclusions: The similar radiologic prevalence and extent of dehiscent sigmoid plates among the age groups suggest that the dehiscence is more commonly a congenital than an acquired condition.

  9. Triple arthrodesis for adult acquired flatfoot.

    Science.gov (United States)

    Catanzariti, Alan R; Dix, Brian T; Richardson, Phillip E; Mendicino, Robert W

    2014-07-01

    The primary goal of triple arthrodesis for stage III and IV adult acquired flatfoot is to obtain a well-aligned plantigrade foot that will support the ankle in optimal alignment. Ancillary procedures including posterior muscle group lengthening, medial displacement calcaneal osteotomy, medial column stabilization, peroneus brevis tenotomy, or transfer and harvest of regional bone graft are often necessary to achieve adequate realignment. Image intensification is helpful in confirming optimal realignment before fixation. Results of triple arthrodesis are enhanced with adequate preparation of joint surfaces, bone graft/orthobiologics, 2-point fixation of all 3 tritarsal joints, and a vertical heel position.

  10. Images

    Data.gov (United States)

    National Aeronautics and Space Administration — Images for the website main pages and all configurations. The upload and access points for the other images are: Website Template RSW images BSCW Images HIRENASD...

  11. MRI of fetal acquired brain lesions

    Energy Technology Data Exchange (ETDEWEB)

    Prayer, Daniela [Department of Radiodiagnostics, Medical University of Vienna (Austria)]. E-mail: daniela.prayer@meduniwien.ac.at; Brugger, Peter C. [Center of Anatomy and Cell Biology, Medical University of Vienna (Austria); Kasprian, Gregor [Department of Radiodiagnostics, Medical University of Vienna (Austria); Witzani, Linde [Department of Radiodiagnostics, Medical University of Vienna (Austria); Helmer, Hanns [Department of Obstetrics and Gynecology, Medical University of Vienna (Austria); Dietrich, Wolfgang [Department of Neurosurgery, Medical University of Vienna (Austria); Eppel, Wolfgang [Department of Obstetrics and Gynecology, Medical University of Vienna (Austria); Langer, Martin [Department of Obstetrics and Gynecology, Medical University of Vienna (Austria)

    2006-02-15

    Acquired fetal brain damage is suspected in cases of destruction of previously normally formed tissue, the primary cause of which is hypoxia. Fetal brain damage may occur as a consequence of acute or chronic maternal diseases, with acute diseases causing impairment of oxygen delivery to the fetal brain, and chronic diseases interfering with normal, placental development. Infections, metabolic diseases, feto-fetal transfusion syndrome, toxic agents, mechanical traumatic events, iatrogenic accidents, and space-occupying lesions may also qualify as pathologic conditions that initiate intrauterine brain damage. MR manifestations of acute fetal brain injury (such as hemorrhage or acute ischemic lesions) can easily be recognized, as they are hardly different from postnatal lesions. The availability of diffusion-weighted sequences enhances the sensitivity in recognizing acute ischemic lesions. Recent hemorrhages are usually readily depicted on T2 (*) sequences, where they display hypointense signals. Chronic fetal brain injury may be characterized by nonspecific changes that must be attributable to the presence of an acquired cerebral pathology. The workup in suspected acquired fetal brain injury also includes the assessment of extra-CNS organs that may be affected by an underlying pathology. Finally, the placenta, as the organ that mediates oxygen delivery from the maternal circulation to the fetus, must be examined on MR images.

  12. MRI of fetal acquired brain lesions

    International Nuclear Information System (INIS)

    Acquired fetal brain damage is suspected in cases of destruction of previously normally formed tissue, the primary cause of which is hypoxia. Fetal brain damage may occur as a consequence of acute or chronic maternal diseases, with acute diseases causing impairment of oxygen delivery to the fetal brain, and chronic diseases interfering with normal, placental development. Infections, metabolic diseases, feto-fetal transfusion syndrome, toxic agents, mechanical traumatic events, iatrogenic accidents, and space-occupying lesions may also qualify as pathologic conditions that initiate intrauterine brain damage. MR manifestations of acute fetal brain injury (such as hemorrhage or acute ischemic lesions) can easily be recognized, as they are hardly different from postnatal lesions. The availability of diffusion-weighted sequences enhances the sensitivity in recognizing acute ischemic lesions. Recent hemorrhages are usually readily depicted on T2 (*) sequences, where they display hypointense signals. Chronic fetal brain injury may be characterized by nonspecific changes that must be attributable to the presence of an acquired cerebral pathology. The workup in suspected acquired fetal brain injury also includes the assessment of extra-CNS organs that may be affected by an underlying pathology. Finally, the placenta, as the organ that mediates oxygen delivery from the maternal circulation to the fetus, must be examined on MR images

  13. Acquiring taste in home economics?

    DEFF Research Database (Denmark)

    Stenbak Larsen, Christian

    2015-01-01

    that the pupils were encouraged to use their senses: listen to things frying, touch the meat to check if it was done and taste the food in the process of seasoning it. But while some children learned what the teachers expected: to produce well tasting food, others learned to cook very salty and hot food...... appreciated by the group of boys, and others again learned to stick with their idiosyncrasies when pressured by the teacher. Conclusions: Children were acquiring taste in the home economic lessons, but not only the kind of tastes that the teacher had planned for. This leads to reflections on the very complex...... process of taste acquiring and to a call for further research into taste acquiring in complex real life contexts as home economics lessons....

  14. And the Winner is - Acquired

    DEFF Research Database (Denmark)

    Henkel, Joachim; Rønde, Thomas; Wagner, Marcus

    2015-01-01

    that then commercialize the innovation. To this end we analyze an innovation game between one incumbent and a large number of entrants. In the first stage, firms compete to develop innovations of high quality. They do so by choosing, at equal cost, the success probability of their R&D approach, where a lower probability...... accompanies higher value in case of success—that is, a more radical innovation. In the second stage, successful entrants bid to be acquired by the incumbent. We assume that entrants cannot survive on their own, so being acquired amounts to a prize in a contest. We identify an equilibrium in which...

  15. Acquired anhidrosis a case report

    Directory of Open Access Journals (Sweden)

    Nair Laxmi

    1992-01-01

    Full Text Available A 30-year -old man was seen for acquired anhidrosis. There was no systemic disease. Vasomotor functions were normal. Biopsy showed normal sweat glands and ducts. Intravenous injection of neostigmine could produce profuse sweating on the face, trunk and arms. The disorder is likely to be due to a peripheral dysautonomia selectively affecting the sudomotor function.

  16. Acquired anhidrosis a case report

    OpenAIRE

    Nair Laxmi; Beena D; Manohar S

    1992-01-01

    A 30-year -old man was seen for acquired anhidrosis. There was no systemic disease. Vasomotor functions were normal. Biopsy showed normal sweat glands and ducts. Intravenous injection of neostigmine could produce profuse sweating on the face, trunk and arms. The disorder is likely to be due to a peripheral dysautonomia selectively affecting the sudomotor function.

  17. Cogema acquires TOTAL's uranium assets

    International Nuclear Information System (INIS)

    On April 28, France's nuclear fuel cycle conglomerate Cogema and petroleum group TOTAL announced a plan in which Cogema will assume ownership of TOTAL's uranium assets worldwide, and as part of the deal, each firm will acquire shares of the other. On June 2, the agreement will be submitted to shareholders and, assuming it is approved, will go into effect this year. The agreement calls for TOTAL to acquire a 10.8-percent share in Cogema, thus becoming its first private sector shareholder, by underwriting a reserve capital increase of FF1.5 billion (approximately US$283 million). In return, Cogema will pay FF2.52 billion for approximately 4.3 percent of TOTAL, as part of a reserve capital increase totalling FF4.07 billion

  18. Occupationally Acquired American Cutaneous Leishmaniasis

    Directory of Open Access Journals (Sweden)

    Maria Edileuza Felinto de Brito

    2012-01-01

    Full Text Available We report two occupationally acquired cases of American cutaneous leishmaniasis (ACL: one accidental laboratory autoinoculation by contaminated needlestick while handling an ACL lesion sample, and one acquired during field studies on bird biology. Polymerase chain reaction (PCR assays of patient lesions were positive for Leishmania, subgenus Viannia. One isolate was obtained by culture (from patient 2 biopsy samples and characterized as Leishmania (Viannia naiffi through an indirect immunofluorescence assay (IFA with species-specific monoclonal antibodies (mAbs and by multilocus enzyme electrophoresis (MLEE. Patients were successfully treated with N-methyl-glucamine. These two cases highlight the potential risks of laboratory and field work and the need to comply with strict biosafety procedures in daily routines. The swab collection method, coupled with PCR detection, has greatly improved ACL laboratory diagnosis.

  19. CNOOC Acquires Oversea Assets Successfully

    Institute of Scientific and Technical Information of China (English)

    Hu Senlin

    2006-01-01

    @@ After last year CNOOC's bidding for buy the US energy company Unocal Corp lost out to the Chevron Corporation, it conducted the crossing-border asset-acquirement again in the beginning of this year. On Jan. 9, 2006,CNOOC Ltd signed a definitive agreement with Nigeria South Atlantic Petroleum Limited (SAPETRO) to acquire a 45 % working interest in an offshore oil developing license OML 130 in Nigeria for US$2.268 billion cash. The purchase will be funded by the internal capital resources of CNOOC Ltd. In which, US$1.75 billion will pay for buying SAPETRO, and the remaining cash will be used to pay for the early operation cost.

  20. Acquired causes of intestinal malabsorption.

    Science.gov (United States)

    van der Heide, F

    2016-04-01

    This review focuses on the acquired causes, diagnosis, and treatment of intestinal malabsorption. Intestinal absorption is a complex process that depends on many variables, including the digestion of nutrients within the intestinal lumen, the absorptive surface of the small intestine, the membrane transport systems, and the epithelial absorptive enzymes. Acquired causes of malabsorption are classified by focussing on the three phases of digestion and absorption: 1) luminal/digestive phase, 2) mucosal/absorptive phase, and 3) transport phase. Most acquired diseases affect the luminal/digestive phase. These include short bowel syndrome, extensive small bowel inflammation, motility disorders, and deficiencies of digestive enzymes or bile salts. Diagnosis depends on symptoms, physical examination, and blood and stool tests. There is no gold standard for the diagnosis of malabsorption. Further testing should be based on the specific clinical context and the suspected underlying disease. Therapy is directed at nutritional support by enteral or parenteral feeding and screening for and supplementation of deficiencies in vitamins and minerals. Early enteral feeding is important for intestinal adaptation in short bowel syndrome. Medicinal treatment options for diarrhoea in malabsorption include loperamide, codeine, cholestyramine, or antibiotics. PMID:27086886

  1. Pneumonia acquired in the Community

    Directory of Open Access Journals (Sweden)

    María Caridad Fragoso Marchante

    2007-06-01

    Full Text Available A bibliographical revision of the main aspects in the diagnosis and treatment of the patients suffering from pneumonia acquired in the community is carried out. Microorganisms responsible for this type of pneumonia are mention in this paper as well as the available diagnostic methods for germs isolation. Different guidelines for diagnosis and treatment of this disease published by several medical societies and scientific institutions are analyzed by means of a review of the stratification index of the patients used in each of them. Aspects related to the duration of the treatment and the possible causes associated with the unfavorable evolution are stated.

  2. Knowledge transfer - Acquiring implicit knowledge

    International Nuclear Information System (INIS)

    Many organisations have recognised the problem of experts taking home a huge amount of specific knowledge, which they have gathered in their department, when they leave. The successor is capable only of acquiring explicit expertise because implicit experiences are not documented and therefore no more available. That is why we have started this pilot study in order to try to conserve the above mentioned tacit and implicit knowledge and to make it available to other colleagues. Using a semi-standardised interview we elicit tacit knowledge from the expert and summarise it in a report. This interview-guideline forms the basis of in-depth investigation for implicit knowledge. (author)

  3. Acquiring 4D Thoracic CT Scans Using Ciné CT Acquisition

    Science.gov (United States)

    Low, Daniel

    One method for acquiring 4D thoracic CT scans is to use ciné acquisition. Ciné acquisition is conducted by rotating the gantry and acquiring x-ray projections while keeping the couch stationary. After a complete rotation, a single set of CT slices, the number corresponding to the number of CT detector rows, is produced. The rotation period is typically sub second so each image set corresponds to a single point in time. The ciné image acquisition is repeated for at least one breathing cycle to acquire images throughout the breathing cycle. Once the images are acquired at a single couch position, the couch is moved to the abutting position and the acquisition is repeated. Post-processing of the images sets typically resorts the sets into breathing phases, stacking images from a specific phase to produce a thoracic CT scan at that phase. Benefits of the ciné acquisition protocol include, the ability to precisely identify the phase with respect to the acquired image, the ability to resort images after reconstruction, and the ability to acquire images over arbitrarily long times and for arbitrarily many images (within dose constraints).

  4. A comparison of CsI:Tl and GOS in a scintillator-CCD detector for nuclear medicine imaging

    Science.gov (United States)

    Bugby, S. L.; Jambi, L. K.; Lees, J. E.

    2016-09-01

    A number of portable gamma cameras for medical imaging use scintillator-CCD based detectors. This paper compares the performance of a scintillator-CCD based portable gamma camera with either a columnar CsI:Tl or a pixelated GOS scintillator installed. The CsI:Tl scintillator has a sensitivity of 40% at 140.5 keV compared to 54% with the GOS scintillator. The intrinsic spatial resolution of the pixelated GOS detector was 1.09 mm, over 4 times poorer than for CsI:Tl. Count rate capability was also found to be significantly lower when the GOS scintillator was used. The uniformity was comparable for both scintillators.

  5. Pruritic acquired nevus of Ota.

    Science.gov (United States)

    Quenan, S; Strueven, V; Saxer, N; Laffitte, E; Kaya, G; Krischer, J; Hafezi, F; Le Gal, F-A

    2013-01-01

    Nevus of Ota is a unilateral, asymptomatic cutaneous and mucosal hyperpigmentation of the face that is congenital or may appear during childhood. We present a case of symptomatic acquired nevus of Ota in an adult, associated with intense pruritus, not described in the literature so far. A 32-year-old woman presented with brownish mottled macules which appeared on her face progressively over 8 days, following the distribution of the first and second divisions of the left trigeminal nerve and partially covering the iris and sclera of the left eye. She reported an intense pruritus in this area. We performed a biopsy on the left forehead, which confirmed the diagnosis of nevus of Ota. Specific stains and immunohistochemistry revealed increased numbers of mast cells. Ophthalmological tests showed acute acquired melanocytosis of the left iris and sclera. The origin of the nevus is still unclear. Several hypotheses suggest a reactivation of melanocytes during their migration from the neural crest. The pruritus reported in our patient may be explained by the increased quantity of mast cells observed in the lesion and/or neuronal stimulation of the ophthalmic and maxillary divisions of the fifth cranial nerve.

  6. Biochemical and Bioimaging Evidence of Cholesterol in Acquired Cholesteatoma

    DEFF Research Database (Denmark)

    Thorsted, Bjarne; Bloksgaard, Maria; Groza, Alexandra;

    2016-01-01

    OBJECTIVES: To quantify the barrier sterols and image the lipid structures in the matrix of acquired cholesteatoma and compare the distribution with that found in stratum corneum from normal skin, with the goal to resolve their potential influence on cholesteatoma growth. METHODS: High-performanc......OBJECTIVES: To quantify the barrier sterols and image the lipid structures in the matrix of acquired cholesteatoma and compare the distribution with that found in stratum corneum from normal skin, with the goal to resolve their potential influence on cholesteatoma growth. METHODS: High......-performance thin-layer chromatography (HPTLC) was used to achieve a quantitative biochemical determination of the sterols. The intercellular lipids were visualized by Coherent Anti-Stokes Raman scattering (CARS) microscopy, which enables label-free imaging of the lipids in intact tissue samples. RESULTS...

  7. Pseudomona pseudomallei community acquired pneumonia

    International Nuclear Information System (INIS)

    This is the first published case report en Colombia about pseudomona pseudomallei community acquired pneumonia. This uncommon pathogen is from the epidemiological standpoint a very important one and medical community should be aware to look after it in those patients where no other etiological pathogen is recovered. A brief summary about epidemiology is showed, emphasizing those regions where it can be found. Likewise, comments about the differential diagnosis are important since it should be considered in those patients where tuberculosis is suspected. This is particularly representative for countries with high tuberculosis rates. Furthermore, a microbiological review is shown, emphasizing on isolation techniques, descriptions about therapeutics and other regarding treatment issues according international standards. Finally; a description about the clinical picture, laboratory findings, treatment and evolution of the case reported are shown for discussion

  8. Lymphoma in acquired generalized lipodystrophy.

    Science.gov (United States)

    Brown, Rebecca J; Chan, Jean L; Jaffe, Elaine S; Cochran, Elaine; DePaoli, Alex M; Gautier, Jean-Francois; Goujard, Cecile; Vigouroux, Corinne; Gorden, Phillip

    2016-01-01

    Acquired generalized lipodystrophy (AGL) is a rare disease thought to result from autoimmune destruction of adipose tissue. Peripheral T-cell lymphoma (PTCL) has been reported in two AGL patients. We report five additional cases of lymphoma in AGL, and analyze the role of underlying autoimmunity and recombinant human leptin (metreleptin) replacement in lymphoma development. Three patients developed lymphoma during metreleptin treatment (two PTCL and one ALK-positive anaplastic large cell lymphoma), and two developed lymphomas (mycosis fungoides and Burkitt lymphoma) without metreleptin. AGL is associated with high risk for lymphoma, especially PTCL. Autoimmunity likely contributes to this risk. Lymphoma developed with or without metreleptin, suggesting metreleptin does not directly cause lymphoma development; a theoretical role of metreleptin in lymphoma progression remains possible. For most patients with AGL and severe metabolic complications, the proven benefits of metreleptin on metabolic disease will likely outweigh theoretical risks of metreleptin in lymphoma development or progression.

  9. Complement's participation in acquired immunity

    DEFF Research Database (Denmark)

    Nielsen, Claus Henrik; Leslie, Robert Graham Quinton

    2002-01-01

    B cell receptor for antigen (BCR), a complex composed of the iC3b/C3d fragment-binding complement type 2 receptor (CR2, CD21) and its signaling element CD19 and the IgG-binding receptor FcgammaRIIb (CD32). The positive or negative outcome of signaling through this triad is determined by the context...... in which antigen is seen, be it alone or in association with natural or induced antibodies and/or C3-complement fragments. The aim of this review is to describe the present status of our understanding of complement's participation in acquired immunity and the regulation of autoimmune responses.......The preliminary evidence for the involvement of complement in promoting primary humoral responses dates back over a quarter of a century. However, it is only in the course of the past decade or so that the detailed mechanisms underlying complement's influence have been characterized in depth. It is...

  10. Acquired pathology of the pediatric spine and spinal cord

    Energy Technology Data Exchange (ETDEWEB)

    Palasis, Susan; Hayes, Laura L. [Children' s Healthcare of Atlanta, Department of Radiology at Scottish Rite, Atlanta, GA (United States)

    2015-09-15

    Pediatric spine pathology poses a diagnostic challenge for radiologists. Acquired spine pathology often yields nonspecific signs and symptoms in children, especially in the younger age groups, and diagnostic delay can carry significant morbidity. This review is focused on some of the more common diagnostic dilemmas we face when attempting to evaluate and diagnose acquired pediatric spine anomalies in daily practice. An understanding of some of the key differentiating features of these disease processes in conjunction with pertinent history, physical exam, and advanced imaging techniques can indicate the correct diagnosis. (orig.)

  11. Acquired vulval lymphangiectases mimicking genital warts

    OpenAIRE

    Sharma Rajeev; Tomar Sudarshan; Chandra Mithilesh

    2002-01-01

    Acquired lymphangiectasia can sometimes occur on the vulva and cause diagnostic difficulties especially if they have a warty appearance. We report a case of acquired vulva I lymphangiectasia which mimicked genital warts.

  12. Acquired vulval lymphangiectases mimicking genital warts

    Directory of Open Access Journals (Sweden)

    Sharma Rajeev

    2002-01-01

    Full Text Available Acquired lymphangiectasia can sometimes occur on the vulva and cause diagnostic difficulties especially if they have a warty appearance. We report a case of acquired vulva I lymphangiectasia which mimicked genital warts.

  13. Colour Image Represention of Multispectral Image Fusion

    OpenAIRE

    Preema Mole; Mathurakani, M

    2016-01-01

    The availability of imaging sensors operating in multiple spectral bands has led to the requirement of image fusion algorithms that would combine the image from these sensors in an efficient way to give an image that is more perceptible to human eye. Multispectral Image fusion is the process of combining images optically acquired in more than one spectral band. In this paper, we present a pixel-level image fusion that combines four images from four different spectral bands namely ...

  14. 12 CFR 583.1 - Acquire.

    Science.gov (United States)

    2010-01-01

    ... AND LOAN HOLDING COMPANIES § 583.1 Acquire. The term acquire means to acquire, directly or indirectly, ownership or control through an acquisition of shares, an acquisition of assets or assumption of liabilities, a merger or consolidation, or any similar transaction....

  15. Infections Acquired in the Garden.

    Science.gov (United States)

    Cunha, Cheston B; Cunha, Burke A

    2015-10-01

    Gardening is a wonderful pastime, and the garden is a very peaceful place to enjoy one's vacation. However, the garden may be a treacherous place for very young or compromised hosts when one takes into account the infectious potential residing in the soil, as well as the insect vectors on plants and animals. Even normal hosts may acquire a variety of infections from the soil, animals, or animal-related insect bites. The location of the garden, its natural animal and insect inhabitants, and the characteristics of the soil play a part in determining its infectious potential. The most important factor making the garden an infectious and dangerous place is the number and interaction of animals, whether they are pets or wild, that temporarily use the garden for part of their daily activities. The clinician should always ask about garden exposure, which will help in eliminating the diagnostic possibilities for the patient. The diagnostic approach is to use epidemiological principles in concert with clinical clues, which together should suggest a reasonable list of diagnostic possibilities. Organ involvement and specific laboratory tests help further narrow the differential diagnosis and determine the specific tests necessary to make a definitive diagnosis. PMID:26542044

  16. Optical imaging of alpha emitters: simulations, phantom, and in vivo results

    Science.gov (United States)

    Boschi, Federico; Meo, Sergio Lo; Rossi, Pier Luca; Calandrino, Riccardo; Sbarbati, Andrea; Spinelli, Antonello E.

    2011-12-01

    There has been growing interest in investigating both the in vitro and in vivo detection of optical photons from a plethora of beta emitters using optical techniques. In this paper we have investigated an alpha particle induced fluorescence signal by using a commercial CCD-based small animal optical imaging system. The light emission of a 241Am source was simulated using GEANT4 and tested in different experimental conditions including the imaging of in vivo tissue. We believe that the results presented in this work can be useful to describe a possible mechanism for the in vivo detection of alpha emitters used for therapeutic purposes.

  17. Clinicopathological associations of acquired erythroblastopenia

    Science.gov (United States)

    Gunes, Gursel; Malkan, Umit Yavuz; Yasar, Hatime Arzu; Eliacik, Eylem; Haznedaroglu, Ibrahim Celalettin; Demiroglu, Haluk; Sayinalp, Nilgun; Aksu, Salih; Etgul, Sezgin; Aslan, Tuncay; Goker, Hakan; Ozcebe, Osman Ilhami; Buyukasik, Yahya

    2015-01-01

    Introduction: Acquired erythroblastopenia (AE) is a rare clinical situation. It is characterized by the reduction of erythroid precursors in the bone marrow together with the low reticulocyte counts in the peripheral blood. Background: Main secondary causes of AE are drugs, Parvovirus B19 and other infectious reasons, lymphoid and myeloid neoplasia, autoimmune diseases, thymoma and pregnancy. The aim of this study is to assess the frequencies and clinical associations of AE via analyzing 12340 bone marrow samples in a retrospective manner. Material and method: Bone marrow aspirations which were obtained from patients who applied to Hacettepe University Hematology Clinic between 2002 and 2013, were analyzed retrospectively. Results: Thirty four erythroblastopenia cases were found. Patients ranged in age from 16 to 80 years with a median of 38 years. Fifteen patients were men (44%) and nineteen were women (56%). In these patients, detected causes of erythroblastopenia were MDS, idiopathic pure red cell aplasia (PRCA), parvovirus infection, post chemotherapy aplasia, plasma proliferative diseases, copper deficiency due to secondary amyloidosis, fever of unknown origin, hemophagocytic syndrome, enteric fever and legionella pneumonia. We found that between those reasons the most common causes of erythroblastopenia are MDS (17.7%) and idiopathic PRCA (17.7%). Discussion: As a result, erythroblastopenia in the bone marrow may be an early sign of MDS. In those AE cases possibility of being MDS must be kept in mind as it can be mistaken for PRCA. Conclusion: To conclude, in adults MDS without excess blast is one of the most common causes of erythroblastopenia in clinical practice and in case of erythroblastopenia the presence of MDS should be investigated. PMID:26885236

  18. 17 CFR 210.8-06 - Real estate operations acquired or to be acquired.

    Science.gov (United States)

    2010-04-01

    ... 17 Commodity and Securities Exchanges 2 2010-04-01 2010-04-01 false Real estate operations acquired or to be acquired. 210.8-06 Section 210.8-06 Commodity and Securities Exchanges SECURITIES AND... Statements of Smaller Reporting Companies § 210.8-06 Real estate operations acquired or to be acquired....

  19. 灰阶血流成像对获得性梗阻性无精症患者睾丸血流灌注的评价%Evaluation of testicular blood perfusion in patients with acquired obstructive azoospermia using B-mode blood flow imaging

    Institute of Scientific and Technical Information of China (English)

    谢军

    2013-01-01

    目的 探讨灰阶血流成像(B-flow)评价获得性梗阻性无精症患者睾丸血流灌注的临床应用价值.方法 使用B-flow和能量多普勒血流成像(PDI)技术观察71例获得性梗阻性无精症患者两侧睾丸的血流灌注情况,以PDI为标准评价B-flow观察获得性梗阻性无精症患者睾丸血流灌注的价值.结果 B-flow在睾丸最大切面检出血管数目:左侧(5.35±0.81)条,右侧(5.27±0.83)条;PDI在睾丸最大切面上检出血管数目:左侧(5.21±0.89)条,右侧(5.10±0.85)条,两者有较高相关性(r=0.82,P=0.00),差异无统计学意义.结论 B-flow对评价获得性梗阻性无精症患者睾丸的血流灌注有重要应用价值,可临床推广.%Objective To explore clinic application value of B — mode blood flow imaging ( B—flow ) in evaluating testicular blood perfusion in patients with, acquired obstructive azoospermia.Methods Seventy—one patients with acquired obstructive azoospermia were examined for observing testicular blood perfusion by B—mode blood flow imaging and power Doppler flow imaging (PDI),Using PD1 as standards.the value of B—flow observaing teslicular blood perfusion in patients with acquired obstructive azoospermia was evaluated.Results Testicular vascular number was detected by B—flow,There were (5.35+0.81 ) blood vessels or. the left,and there were ( 5.27+0.83) blood vessels on the right .Testicular vascular number was detected by PDI. There were v5.2i±0.89) blood vessels on the left, and there were (5.10×0.85) blood vessels on the right.There was a correlation between them (r =0.82,P=0.00).Thcre was no significant difference between thcm.Conclusion B-flow has an important application value in evaluating testicular blood perfusion in patients with acquired obstructive azoospcrmia.

  20. Acquired Dyslexia and Dysgraphia in Chinese

    Directory of Open Access Journals (Sweden)

    Wengang Yin

    2005-01-01

    Full Text Available Understanding how the mappings between orthography and phonology in alphabetic languages are learned, represented and processed has been enhanced by the cognitive neuropsychological investigation of patients with acquired reading and writing disorders. During the past decade, this methodology has been extended to understanding reading and writing in Chinese leading to new insights about language processing, dyslexia and dysgraphia. The aim of this paper is to review reports of patients who have acquired dyslexia and acquired dysgraphia in Chinese and describe the functional architecture of the reading and writing system. Our conclusion is that the unique features of Chinese script will determine the symptoms of acquired dyslexia and dysgraphia in Chinese.

  1. CCD based beam loss monitor for ion accelerators

    Science.gov (United States)

    Belousov, A.; Mustafin, E.; Ensinger, W.

    2014-04-01

    Beam loss monitoring is an important aspect of proper accelerator functioning. There is a variety of existing solutions, but each has its own disadvantages, e.g. unsuitable dynamic range or time resolution, high cost, or short lifetime. Therefore, new options are looked for. This paper shows a method of application of a charge-coupled device (CCD) video camera as a beam loss monitor (BLM) for ion beam accelerators. The system was tested with a 500 MeV/u N+7 ion beam interacting with an aluminum target. The algorithms of camera signal processing with LabView based code and beam loss measurement are explained. Limits of applicability of this monitor system are discussed.

  2. Mariner 10 Image Archive

    Data.gov (United States)

    National Aeronautics and Space Administration — The Mariner 10 Image Archive includes tools to view shaded relief maps of the surface of Mercury, a 3D globe, and all images acquired by NASA's Mariner 10 mission.

  3. And the Winner is – Acquired

    DEFF Research Database (Denmark)

    Henkel, Joachim; Rønde, Thomas; Wagner, Marcus

    value in case of success—that is, a more radical innovation. In the second stage, successful entrants bid to be acquired by the incumbent. We assume that entrants cannot survive on their own, so being acquired amounts to a ‘prize’ in a contest. We identify an equilibrium in which the incumbent chooses...

  4. Acquired Zinc Deficiency in an Adult Female

    OpenAIRE

    Mohanan Saritha; Divya Gupta; Laxmisha Chandrashekar; Devinder M Thappa; Nachiappa G Rajesh

    2012-01-01

    Acrodermatitis enteropathica is an autosomal recessive inherited disorder of zinc absorption. Acquired cases are reported occasionally in patients with eating disorders or Crohn′s disease. We report a 24-year-old housewife with acquired isolated severe zinc deficiency with no other comorbidities to highlight the rare occurrence of isolated nutritional zinc deficiency in an otherwise normal patient.

  5. ATF beam image monitor software

    International Nuclear Information System (INIS)

    We report about software for the beam image analysis at ATF. We developed image analysis software with a Linux computer. It acquire image data from a video and an IEEE1394 digital camera of the analog. (author)

  6. Seeing the eyes in acquired prosopagnosia.

    Science.gov (United States)

    Pancaroglu, Raika; Hills, Charlotte S; Sekunova, Alla; Viswanathan, Jayalakshmi; Duchaine, Brad; Barton, Jason J S

    2016-08-01

    Case reports have suggested that perception of the eye region may be impaired more than that of other facial regions in acquired prosopagnosia. However, it is unclear how frequently this occurs, whether such impairments are specific to a certain anatomic subtype of prosopagnosia, and whether these impairments are related to changes in the scanning of faces. We studied a large cohort of 11 subjects with this rare disorder, who had a variety of occipitotemporal or anterior temporal lesions, both unilateral and bilateral. Lesions were characterized by functional and structural imaging. Subjects performed a perceptual discrimination test in which they had to discriminate changes in feature position, shape, or external contour. Test conditions were manipulated to stress focused or divided attention across the whole face. In a second experiment we recorded eye movements while subjects performed a face memory task. We found that greater impairment for eye processing was more typical of subjects with occipitotemporal lesions than those with anterior temporal lesions. This eye selectivity was evident for both eye position and shape, with no evidence of an upper/lower difference for external contour. A greater impairment for eye processing was more apparent under attentionally more demanding conditions. Despite these perceptual deficits, most subjects showed a normal tendency to scan the eyes more than the mouth. We conclude that occipitotemporal lesions are associated with a partially selective processing loss for eye information and that this deficit may be linked to loss of the right fusiform face area, which has been shown to have activity patterns that emphasize the eye region. PMID:27288649

  7. Hospital-Acquired Condition Reduction Program

    Data.gov (United States)

    U.S. Department of Health & Human Services — In October 2014, CMS began reducing Medicare payments for subsection (d) hospitals that rank in the worst performing quartile with respect to hospital-acquired...

  8. Enhancing Medicares Hospital Acquired Conditions Policy

    Data.gov (United States)

    U.S. Department of Health & Human Services — The current Medicare policy of non-payment to hospitals for Hospital Acquired Conditions (HAC) seeks to avoid payment for preventable complications identified...

  9. The Acquired Immunodeficiency Syndrome: current status.

    OpenAIRE

    Quagliarello, V.

    1982-01-01

    A recently recognized syndrome of acquired immunodeficiency (Acquired Immunodeficiency Syndrome-AIDS) has arisen since June 1981. It has received international attention. The clinical spectrum consists of repeated opportunistic infections, rare malignancies, and autoimmune phenomena, occurring in previously healthy adults with no history of an immunologic disorder. The population subset at risk for this syndrome appears to be predominantly homosexual American males and intravenous drug abuser...

  10. Infections acquired in clinical laboratories in Utah.

    OpenAIRE

    Jacobson, J.T.; Orlob, R B; Clayton, J L

    1985-01-01

    We reviewed laboratory-acquired infections occurring in Utah from 1978 through 1982. Written and telephone interviews of supervisors of 1,191 laboratorians revealed an estimated annual incidence of 3 laboratory-acquired infections per 1,000 employees. Infections, in order of frequency, included hepatitis B (clinical cases), shigellosis, pharyngitis, cellulitis, tuberculosis (skin test conversion), conjunctivitis, and non-A, non-B hepatitis. One-half of large laboratories (over 25 employees), ...

  11. Synthetic Aperture Ultrasound Imaging

    DEFF Research Database (Denmark)

    Jensen, Jørgen Arendt; Nikolov, Svetoslav; Gammelmark, Kim Løkke;

    2006-01-01

    The paper describes the use of synthetic aperture (SA) imaging in medical ultrasound. SA imaging is a radical break with today's commercial systems, where the image is acquired sequentially one image line at a time. This puts a strict limit on the frame rate and the possibility of acquiring...... of SA imaging. Due to the complete data set, it is possible to have both dynamic transmit and receive focusing to improve contrast and resolution. It is also possible to improve penetration depth by employing codes during ultrasound transmission. Data sets for vector flow imaging can be acquired using...... short imaging sequences, whereby both the correct velocity magnitude and angle can be estimated. A number of examples of both phantom and in-vivo SA images will be presented measured by the experimental ultrasound scanner RASMUS to demonstrate the many benefits of SA imaging....

  12. Surgical correction of acquired unilateral diaphragmatic paralysis by plication technique

    Directory of Open Access Journals (Sweden)

    Christos F. Kampolis

    2013-06-01

    Full Text Available Summary: Acquired diaphragmatic paralysis may compromise lung mechanics and cause dyspnoea and/or lead to respiratory failure in the long term. A 76 year-old female patient presented with progressive worsening of dyspnoea and spirometric indices, and imaging studies revealed elevation of the left hemidiaphragm. Surgical correction was carried out by diaphragmatic plication technique, through a mini-thoracotomy approach. Immediate alleviation (within days of her symptoms was observed, while improvement of radiological and pulmonary function tests occurred some weeks later. Pneumon 2013,26(2

  13. Small UAV-Acquired, High-resolution, Georeferenced Still Imagery

    Energy Technology Data Exchange (ETDEWEB)

    Ryan Hruska

    2005-09-01

    Currently, small Unmanned Aerial Vehicles (UAVs) are primarily used for capturing and down-linking real-time video. To date, their role as a low-cost airborne platform for capturing high-resolution, georeferenced still imagery has not been fully utilized. On-going work within the Unmanned Vehicle Systems Program at the Idaho National Laboratory (INL) is attempting to exploit this small UAV-acquired, still imagery potential. Initially, a UAV-based still imagery work flow model was developed that includes initial UAV mission planning, sensor selection, UAV/sensor integration, and imagery collection, processing, and analysis. Components to support each stage of the work flow are also being developed. Critical to use of acquired still imagery is the ability to detect changes between images of the same area over time. To enhance the analysts’ change detection ability, a UAV-specific, GIS-based change detection system called SADI or System for Analyzing Differences in Imagery is under development. This paper will discuss the associated challenges and approaches to collecting still imagery with small UAVs. Additionally, specific components of the developed work flow system will be described and graphically illustrated using varied examples of small UAV-acquired still imagery.

  14. Do Acquirer Capabilities Affect Acquisition Performance? Examining Strategic and Effectiveness Capabilities in Acquirers

    OpenAIRE

    Mudde, Paul A.; Brush, Thomas

    2006-01-01

    This paper examines acquisition performance from the perspective of acquirer capabilities. It argues that the strategic capabilities underpinning a firm’s competitive strategy can be utilized to create economic value in acquisitions. Acquirers with strong cost leadership capabilities are expected to leverage these capabilities to reduce post-acquisition costs as they integrate acquisition targets. Acquirers with strong differentiation capabilities are expected to utilize their strategic capab...

  15. Enhancement of the low resolution image quality using randomly sampled data for multi-slice MR imaging

    OpenAIRE

    Pang, Yong; Yu, Baiying; Zhang, Xiaoliang

    2014-01-01

    Low resolution images are often acquired in in vivo MR applications involving in large field-of-view (FOV) and high speed imaging, such as, whole-body MRI screening and functional MRI applications. In this work, we investigate a multi-slice imaging strategy for acquiring low resolution images by using compressed sensing (CS) MRI to enhance the image quality without increasing the acquisition time. In this strategy, low resolution images of all the slices are acquired using multiple-slice imag...

  16. Differential Protein Expression in Congenital and Acquired Cholesteatomas.

    Directory of Open Access Journals (Sweden)

    Seung-Ho Shin

    Full Text Available Congenital cholesteatomas are epithelial lesions that present as an epithelial pearl behind an intact eardrum. Congenital and acquired cholesteatomas progress quite differently from each other and progress patterns can provide clues about the unique origin and pathogenesis of the abnormality. However, the exact pathogenic mechanisms by which cholesteatomas develop remain unknown. In this study, key proteins that directly affect cholesteatoma pathogenesis are investigated with proteomics and immunohistochemistry. Congenital cholesteatoma matrices and retroauricular skin were harvested during surgery in 4 patients diagnosed with a congenital cholesteatoma. Tissue was also harvested from the retraction pocket in an additional 2 patients during middle ear surgery. We performed 2-dimensional (2D electrophoresis to detect and analyze spots that are expressed only in congenital cholesteatoma and matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF/MS to separate proteins by molecular weight. Protein expression was confirmed by immunohistochemical staining. The image analysis of 2D electrophoresis showed that 4 congenital cholesteatoma samples had very similar protein expression patterns and that 127 spots were exclusively expressed in congenital cholesteatomas. Of these 127 spots, 10 major spots revealed the presence of titin, forkhead transcription activator homolog (FKH 5-3, plectin 1, keratin 10, and leucine zipper protein 5 by MALDI-TOF/MS analysis. Immunohistochemical staining showed that FKH 5-3 and titin were expressed in congenital cholesteatoma matrices, but not in acquired cholesteatomas. Our study shows that protein expression patterns are completely different in congenital cholesteatomas, acquired cholesteatomas, and skin. Moreover, non-epithelial proteins, including FKH 5-3 and titin, were unexpectedly expressed in congenital cholesteatoma tissue. Our data indicates that congenital cholesteatoma origins

  17. Avaliação da qualidade das imagens digitais adquiridas com diferentes resoluções em um sistema de armazenamento de fósforo Evaluation of the quality of digital images acquired with different resolutions in a storage phosphor system

    Directory of Open Access Journals (Sweden)

    Solange Maria de ALMEIDA

    2000-09-01

    Full Text Available O objetivo do presente trabalho foi avaliar comparativamente a qualidade das imagens adquiridas, por meio da placa de fósforo, com três diferentes resoluções - 150, 300 e 600 dpi, e a eficiência de alguns recursos de manipulação disponíveis no software do sistema estudado. Os objetos de análise constituíram-se de quinze dentes com a lima 8 em seu interior, cujas mensurações endodônticas foram realizadas por cinco avaliadores. O sistema digital utilizado foi o DenOptix (Dentsply International/Gendex Dental X-Ray Division, Des Plaines, IL. Os resultados mostraram diferença estatística entre as diferentes resoluções empregadas, com as imagens adquiridas com 150 dpi apresentando-se de qualidade inferior às de 300 e 600 dpi, estas equivalentes. Os diferentes recursos digitais empregados não se apresentaram estatisticamente significantes entre si. Com base nos resultados, conclui-se que as imagens de 150 dpi apresentam-se com qualidade inferior àquelas adquiridas com 300 e 600 dpi, que oferecem similar nível de eficiência, imagens em condições satisfatórias para uma análise radiográfica. Quanto a aplicação dos diferentes recursos de manipulação estudados, pode-se concluir, em função dos resultados equivalentes que apresentaram, que, em mensurações endodônticas, a escolha de se trabalhar com um recurso isoladamente ou em associação fica ao encargo de um critério subjetivo de seleção.The aim of this paper was to evaluate the quality of the image acquired with the DenOptix storage phosphor plate (Dentsply International/Gendex Dental X-Ray Division, Des Plaines, IL, with three different resolutions - 150, 300 and 600 dpi, as well as the efficiency of some tools that are available in such a kind of software. The objects analyzed were 15 teeth containing a #8 endodontic file in their root canal. Endodontic measurements were performed by 5 examiners. The results showed a statistically significant difference between

  18. Method of assessing heterogeneity in images

    Energy Technology Data Exchange (ETDEWEB)

    Jacob, Richard E.; Carson, James P.

    2016-08-23

    A method of assessing heterogeneity in images is disclosed. 3D images of an object are acquired. The acquired images may be filtered and masked. Iterative decomposition is performed on the masked images to obtain image subdivisions that are relatively homogeneous. Comparative analysis, such as variogram analysis or correlogram analysis, is performed of the decomposed images to determine spatial relationships between regions of the images that are relatively homogeneous.

  19. Contribution to the tracking and the 3D reconstruction of scenes composed of torus from image sequences a acquired by a moving camera; Contribution au suivi et a la reconstruction de scenes constituees d`objet toriques a partir de sequences d`images acquises par une camera mobile

    Energy Technology Data Exchange (ETDEWEB)

    Naudet, S

    1997-01-31

    The three-dimensional perception of the environment is often necessary for a robot to correctly perform its tasks. One solution, based on the dynamic vision, consists in analysing time-varying monocular images to estimate the spatial geometry of the scene. This thesis deals with the reconstruction of torus by dynamic vision. Though this object class is restrictive, it enables to tackle the problem of reconstruction of bent pipes usually encountered in industrial environments. The proposed method is based on the evolution of apparent contours of objects in the sequence. Using the expression of torus limb boundaries, it is possible to recursively estimate the object three-dimensional parameters by minimising the error between the predicted projected contours and the image contours. This process, which is performed by a Kalman filter, does not need a precise knowledge of the camera displacement or any matching of the tow limbs belonging to the same object. To complete this work, temporal tracking of objects which deals with occlusion situations is proposed. The approach consists in modeling and interpreting the apparent motion of objects in the successive images. The motion interpretation, based on a simplified representation of the scene, allows to recover pertinent three-dimensional information which is used to manage occlusion situations. Experiments, on synthetic and real images, proves he validity of the tracking and the reconstruction processes. (author) 127 refs.

  20. Immunomodulation in community-acquired pneumonia

    NARCIS (Netherlands)

    Remmelts, H.H.F.

    2013-01-01

    Community-acquired pneumonia (CAP) is a common disease with considerable morbidity and mortality, despite effective antibiotic treatment. In this thesis, we showed that the major causative microorganisms in CAP trigger distinct inflammatory response profiles in the host. While an inflammatory respon

  1. Prevention of hospital-acquired hyponatraemia

    DEFF Research Database (Denmark)

    Lunøe, Mathilde; Overgaard-Steensen, C

    2015-01-01

    prevention of hospital-acquired hyponatraemia is an understanding of what determines plasma sodium concentration (P-[Na(+) ]) in the individual patient. P-[Na(+) ] is determined by balances of water and cations according to Edelman. This paper discusses the mechanisms influencing water and cation balances...

  2. In vivo mechanisms of acquired thymic tolerance

    DEFF Research Database (Denmark)

    Chen, W; Issazadeh-Navikas, Shohreh; Sayegh, M H;

    1997-01-01

    Injection of antigen into the thymus of adult animals induces specific systemic tolerance, but the mechanisms of acquired thymic tolerance are not well understood. To investigate these mechanisms we used a model of intrathymic injection of ovalbumin (OVA) in BALB/c mice. We show an antigen-specif...

  3. Acquired secondary Grynfeltt's hernia: a case report

    International Nuclear Information System (INIS)

    Lumbar hernia is a rare condition whose diagnosis is hardly achieved. The prevalence is higher in elderly men. The present case report describes the case of a male, 78-year-old patient who underwent pleural effusion drainage 17 years before presenting with clinical manifestations and tomographic findings compatible with acquired secondary Grynfeltt's hernia. (author)

  4. Mitral valve repair in acquired dextrocardia.

    Science.gov (United States)

    Elmistekawy, Elsayed; Chan, Vincent; Hynes, Mark; Mesana, Thierry

    2015-10-01

    Surgical correction of valvular heart disease in patients with dextrocardia is extremely rare. We report a surgical case of mitral valve repair in a patient with acquired dextrocardia. Successful mitral valve repair was performed through a right lateral thoracotomy. We describe our surgical strategy and summarize the literature.

  5. Severe acquired anaemia in Africa: new concepts

    NARCIS (Netherlands)

    M. Boele van Hensbroek; F. Jonker; I. Bates

    2011-01-01

    Severe anaemia is common in Africa. It has a high mortality and particularly affects young children and pregnant women. Recent research provides new insights into the mechanisms and causes of severe acquired anaemia and overturns accepted dogma. Deficiencies of vitamin B12 and vitamin A, but not of

  6. Eye Movement Correlates of Acquired Central Dyslexia

    Science.gov (United States)

    Schattka, Kerstin I.; Radach, Ralph; Huber, Walter

    2010-01-01

    Based on recent progress in theory and measurement techniques, the analysis of eye movements has become one of the major methodological tools in experimental reading research. Our work uses this approach to advance the understanding of impaired information processing in acquired central dyslexia of stroke patients with aphasia. Up to now there has…

  7. Facility for low-dose digital scanning of a large-area image of ionizing radiation

    International Nuclear Information System (INIS)

    The facility scans the unreduced X-ray image by means of moving line sensors which work in parallel. The length of the sensors is much smaller than the width of the image. The facility comprises about 20 identical modules, owing to which the output of the serial manufacture can be increased, and CCD-based line sensors can be employed which are very sensitive and inexpensive. The X-ray image can be taken at the virtually lowest exposure possible, and owing to the parallelization of the scanning process, the scanning rate can be increased considerably as compared with the existing facilities. The facility consists of an ionizing radiation source against which are positioned a movable diaphragm fitted with slits and a movable support plate carrying the line sensors. The sensors make up the line detector whose length is equal to that of the image scanned, synchronously movable with the movable slit diaphragm. (M.D.). 3 figs

  8. Performance evaluation of CCD- and mobile-phone-based near-infrared fluorescence imaging systems with molded and 3D-printed phantoms

    Science.gov (United States)

    Wang, Bohan; Ghassemi, Pejhman; Wang, Jianting; Wang, Quanzeng; Chen, Yu; Pfefer, Joshua

    2016-03-01

    Increasing numbers of devices are emerging which involve biophotonic imaging on a mobile platform. Therefore, effective test methods are needed to ensure that these devices provide a high level of image quality. We have developed novel phantoms for performance assessment of near infrared fluorescence (NIRF) imaging devices. Resin molding and 3D printing techniques were applied for phantom fabrication. Comparisons between two imaging approaches - a CCD-based scientific camera and an NIR-enabled mobile phone - were made based on evaluation of the contrast transfer function and penetration depth. Optical properties of the phantoms were evaluated, including absorption and scattering spectra and fluorescence excitation-emission matrices. The potential viability of contrastenhanced biological NIRF imaging with a mobile phone is demonstrated, and color-channel-specific variations in image quality are documented. Our results provide evidence of the utility of novel phantom-based test methods for quantifying image quality in emerging NIRF devices.

  9. Processed pseudogenes acquired somatically during cancer development

    OpenAIRE

    Cooke, Susanna L.; Shlien, Adam; Marshall, John; Pipinikas, Christodoulos P; Martincorena, Inigo; Tubio, Jose M. C.; Li, Yilong; Menzies, Andrew; Mudie, Laura; Ramakrishna, Manasa; Yates, Lucy; Davies, Helen; Bolli, Niccolo; Bignell, Graham R; Tarpey, Patrick S.

    2014-01-01

    Cancer evolves by mutation, with somatic reactivation of retrotransposons being one such mutational process. Germline retrotransposition can cause processed pseudogenes, but whether this occurs somatically has not been evaluated. Here we screen sequencing data from 660 cancer samples for somatically acquired pseudogenes. We find 42 events in 17 samples, especially non-small cell lung cancer (5/27) and colorectal cancer (2/11). Genomic features mirror those of germline LINE element retrotransp...

  10. The pathophysiology of acquired premature ejaculation.

    Science.gov (United States)

    McMahon, Chris G; Jannini, Emmanuele A; Serefoglu, Ege C; Hellstrom, Wayne J G

    2016-08-01

    The second Ad Hoc International Society for Sexual Medicine (ISSM) Committee for the Definition of Premature Ejaculation defined acquired premature ejaculation (PE) as a male sexual dysfunction characterized by a the development of a clinically significant and bothersome reduction in ejaculation latency time in men with previous normal ejaculatory experiences, often to about 3 minutes or less, the inability to delay ejaculation on all or nearly all vaginal penetrations, and the presence of negative personal consequences, such as distress, bother, frustration and/or the avoidance of sexual intimacy. The literature contains a diverse range of biological and psychological etiological theories. Acquired PE is commonly due to sexual performance anxiety, psychological or relationship problems, erectile dysfunction (ED), and occasionally prostatitis and hyperthyroidism, consistent with the predominant organic etiology of acquired PE, men with this complaint are usually older, have a higher mean BMI and a greater incidence of comorbid disease including hypertension, sexual desire disorder, diabetes mellitus, chronic prostatitis, and ED compared to lifelong, variable and subjective PE. PMID:27652216

  11. Clinical, Radiological, Microbiological, and Histopathological Aspects of Acquired Dacryocystoceles

    Directory of Open Access Journals (Sweden)

    Selam Yekta Sendul

    2014-01-01

    Full Text Available Purpose. The aim of this study is to investigate the etiology and the clinical, microbiological, histopathological, and radiological findings of acquired dacryocystoceles. Methods. In this retrospective study, we reviewed the clinical records of 10 eyes of 8 patients with dacryocystoceles who underwent external dacryocystorhinostomy (DCR surgery. Etiology, presenting symptoms and radiological findings as well as microbiological and histopathological assessment results and outcome were analyzed. Results. The records of 8 patients with dacryocystoceles were included in this study. In the histopathological evaluations of the samples collected from the lacrimal sac wall, chronic inflammation was found in all biopsied samples and fibrosis was observed in two histopathological evaluations. Computerized tomography (CT imaging showed fluid collection separated from adjacent tissues by a thin rim, corresponding to dacryocystoceles in the sac. In the microbiological culture examination of samples collected from the fluid within the cyst, no bacterial growth in 5 eyes, gram-negative bacillus growth in 3 eyes, and gram-positive cocci growth in 2 eyes were found. Conclusions. Acquired dacryocystoceles were observed extremely rarely and a definite pathogenic agent could not be identified in any of the cases, either microbiologically or histologically, whereas chronic inflammation was detected in all cases in our study.

  12. Physical Activity and Self-Perceptions among Hong Kong Chinese with an Acquired Physical Disability

    Science.gov (United States)

    Sit, Cindy H. P.; Lau, Caren H. L.; Vertinsky, Patricia

    2009-01-01

    This study investigated the association between physical activity and self-perceptions such as body image, physical self-concept, and self-esteem among persons with an acquired physical disability in a non-Western population. Other personal variables such as gender and time of onset of disability were also examined. A convenience sample of 66 Hong…

  13. 后天性感音神经性聋患者听觉中枢磁共振弥散张量成像研究%Diffusion Tensor Imaging Study of Central Auditory Pathway in Patients with Acquired Sensorineural Hearing Loss

    Institute of Scientific and Technical Information of China (English)

    祝康; 何莹; 侯瑾; 闫静; 郑国玺; 许珉; 白芝兰

    2015-01-01

    目的:探讨后天性感音神经性聋(sensorineural hearing loss ,SNHL)及其病程对听觉中枢白质的影响。方法选后天性SNHL患者30例,根据发病时间分为突发性聋组15例和病程2年以上的SNHL组15例;并选择15例同期行M RI检查的听力正常的其它患者为对照组;运用磁共振弥散张量成像(diffusion tensor imaging , DTI)技术观察各组受试者听觉中枢下丘和外侧丘系的弥散相关参数,包括:部分各向异性(factional anisotropy , FA)值、径向弥散(radial diffusivity ,RD)、轴向弥散(axial diffusivity ,AD)及平均弥散(mean diffusivity ,MD)。结果突聋组、病程2年以上的 SNHL 组及对照组双侧下丘 FA 值大小依次为SNHL 组<对照组<突聋组(P<0.05),对照组和突聋组与2年以上SNHL组间差异均有统计学意义(P<0.05);外侧丘系右侧RD值大小依次为突聋组<对照组<SNHL组(P<0.05),右侧MD值大小依次为对照组<突聋组<SNHL组,且两两比较差异均有统计学意义(P<0.05)。三组下丘及外侧丘系AD值差异无统计学意义(均 P>0.05)。结论突聋患者的听觉中枢未发生明显异常的改变,而病程大于2年以上的后天性SNHL患者听觉中枢神经纤维束明显受到破坏,提示感音神经性听觉损失患者的病程长短对听觉传导通路的结构变化有影响。%Objective Magnetic resonance diffusion tensor imaging (DTI) was applied to study the cantral auditong pathway in patients with .Methods A total of 30 cases of acquired hearing loss patients were divided into 2 groups ,group 1 (15 ,sudden deafness) and group 2 (15 ,with duration up to 2 years SNHL group from the time of onset) .A total of 15 cases of normal-hearing patients on MRI examination were selected as the control group for the same period .All subjects received DTI of whole brain .The values of the whole brain DTI were

  14. A combined micro-PET/CT scanner for small animal imaging

    International Nuclear Information System (INIS)

    A micro-PET/CT system was developed by combination of an in-house micro-CT and a microPET[reg] R4 scanner. The cone-beam micro-CT consists of a rotational gantry that fits an X-ray tube, a CCD-based X-ray detector, and motor-driven linear stages. The gantry was designed to be coaxial with the scanner of microPET'' (registered) R4. It can be moved for the convenience of mounting the Ge-68 point-source holder for PET's calibration. The image volumes obtained from two modalities is registered by a pre-determined, inherent spatial transformation function. This hardware-approach fusion, which provides accurate and no labor-intensive alignment, is suitable for mass scanning. The micro-PET/CT system has been operated successfully. Merging the anatomical and functional images benefit studies of the small animal imaging

  15. Acquired prosopagnosia without word recognition deficits.

    Science.gov (United States)

    Susilo, Tirta; Wright, Victoria; Tree, Jeremy J; Duchaine, Bradley

    2015-01-01

    It has long been suggested that face recognition relies on specialized mechanisms that are not involved in visual recognition of other object categories, including those that require expert, fine-grained discrimination at the exemplar level such as written words. But according to the recently proposed many-to-many theory of object recognition (MTMT), visual recognition of faces and words are carried out by common mechanisms [Behrmann, M., & Plaut, D. C. ( 2013 ). Distributed circuits, not circumscribed centers, mediate visual recognition. Trends in Cognitive Sciences, 17, 210-219]. MTMT acknowledges that face and word recognition are lateralized, but posits that the mechanisms that predominantly carry out face recognition still contribute to word recognition and vice versa. MTMT makes a key prediction, namely that acquired prosopagnosics should exhibit some measure of word recognition deficits. We tested this prediction by assessing written word recognition in five acquired prosopagnosic patients. Four patients had lesions limited to the right hemisphere while one had bilateral lesions with more pronounced lesions in the right hemisphere. The patients completed a total of seven word recognition tasks: two lexical decision tasks and five reading aloud tasks totalling more than 1200 trials. The performances of the four older patients (3 female, age range 50-64 years) were compared to those of 12 older controls (8 female, age range 56-66 years), while the performances of the younger prosopagnosic (male, 31 years) were compared to those of 14 younger controls (9 female, age range 20-33 years). We analysed all results at the single-patient level using Crawford's t-test. Across seven tasks, four prosopagnosics performed as quickly and accurately as controls. Our results demonstrate that acquired prosopagnosia can exist without word recognition deficits. These findings are inconsistent with a key prediction of MTMT. They instead support the hypothesis that face

  16. Expert games: means to acquire expert knowledge

    Directory of Open Access Journals (Sweden)

    G. Ginkul

    1993-06-01

    Full Text Available This article describes the idea and use of non-traditional technique designed to acquire Expert's knowledge for Expert Systems. The procedures, called "Expert Games", look outwardly as well-known computer "playthings" and at the same time are strong means for Knowledge Acquisition. If Expert wants to succeed, he must to use his professional knowledge. After analyzing game operations of an Expert it is possible to resolve reverse problem - to define which what kind of knowledge have been used for making Expert's decision during the game.

  17. Clinicopathological correlation of acquired hypopigmentary disorders

    Directory of Open Access Journals (Sweden)

    Anisha B Patel

    2013-01-01

    Full Text Available Acquired hypopigmentary disorders comprise a significant group of disorders that affect Indians and Asians. The pigment disturbance in darker skin individuals can be very distressing to the patient and the family. These disorders cover a wide array of pathologies including infections, autoimmune processes, lymphoproliferative disorders, and sclerosing diseases. Histological diagnosis is particularly important because treatments for these diseases are varied and specific. This review will focus on histopathological diagnosis based on clinicopathological correlation for commonly encountered disorders such as leprosy, vitiligo, lichen sclerosus, pityriasis alba (PA, and pityriasis versicolor (PV. Atypical or uncommon clinical presentation of classic diseases such as hypopigmented mycosis fungoides (HMF and hypopigmented sarcoidosis are also included.

  18. Acquired plate-like osteoma cutis.

    Science.gov (United States)

    Vashi, Neelam; Chu, Julie; Patel, Rishi

    2011-10-15

    Plate-like osteoma cutis is a rare disorder that has been historically classified as a congenital syndrome. It has a possible relationship to a mutation in the gene (GNAS1) that encodes the α-subunit of the stimulatory G protein, which regulates adenyl cyclase activity. We report a case of extensive plaque-like masses on the scalp and face with no abnormalities in calcium or phosphate metabolism and no preceding inflammatory cutaneous conditions. With less than ten reported cases, to our knowledge, this is one the few cases of acquired plate-like osteoma cutis described in the literature.

  19. Acquired Inventors’ Productivity after Horizontal Acquisition

    DEFF Research Database (Denmark)

    Colombo, Massimo G.; Moreira, Solon; Rabbiosi, Larissa

    of the multifaceted nature of the integration process further enhances our understanding of which conditions will be more or less detrimental for corporate inventors. We focus on R&D teams which are the immediate organizational context in which inventors operate and drawing on insights from learning theory...... and evolutionary economics we posit and find that the reorganization of R&D teams after acquisition harms acquired inventors? innovative performance. Though, the implementation of other integration decisions can mitigate or aggravate this negative effect....

  20. Acquired Congenital Malalignment of the Great Toenails

    Science.gov (United States)

    Decker, Ashley; Scher, Richard K.; Avarbock, Andrew

    2016-01-01

    Congenital malalignment is the lateral deviation of the nail plate along the longitudinal axis due to the lateral rotation of the nail matrix. The nail plate grows out in ridges caused by repeated microtrauma to the nail. Common complications include onychomycosis, Pseudomonas infection and acute or chronic paronychia. Treatment options range from conservative management to surgical options including realignment and nail matrixectomy. Congenital malalignment usually presents in infancy or childhood, but we present two cases of acquired malalignment occurring in the teenage years. PMID:27171597

  1. Medical Image Fusion

    Directory of Open Access Journals (Sweden)

    Mitra Rafizadeh

    2007-08-01

    Full Text Available Technological advances in medical imaging in the past two decades have enable radiologists to create images of the human body with unprecedented resolution. MRI, PET,... imaging devices can quickly acquire 3D images. Image fusion establishes an anatomical correlation between corresponding images derived from different examination. This fusion is applied either to combine images of different modalities (CT, MRI or single modality (PET-PET."nImage fusion is performed in two steps:"n1 Registration: spatial modification (eg. translation of model image relative to reference image in order to arrive at an ideal matching of both images. Registration methods are feature-based and intensity-based approaches."n2 Visualization: the goal of it is to depict the spatial relationship between the model image and refer-ence image. We can point out its clinical application in nuclear medicine (PET/CT.

  2. Asian elephants acquire inaccessible food by blowing.

    Science.gov (United States)

    Mizuno, Kaori; Irie, Naoko; Hiraiwa-Hasegawa, Mariko; Kutsukake, Nobuyuki

    2016-01-01

    Many animals acquire otherwise inaccessible food with the aid of sticks and occasionally water. As an exception, some reports suggest that elephants manipulate breathing through their trunks to acquire inaccessible food. Here, we report on two female Asian elephants (Elephas maximus) in Kamine Zoo, Japan, who regularly blew to drive food within their reach. We experimentally investigated this behaviour by placing foods in inaccessible places. The elephants blew the food until it came within accessible range. Once the food was within range, the elephants were increasingly less likely to blow as the distance to the food became shorter. One subject manipulated her blowing duration based on food distance: longer when the food was distant. These results suggest that the elephants used their breath to achieve goals: that is, they used it not only to retrieve the food but also to fine-tune the food position for easy grasping. We also observed individual differences in the elephants' aptitude for this technique, which altered the efficiency of food acquisition. Thus, we added a new example of spontaneous behaviour for achieving a goal in animals. The use of breath to drive food is probably unique to elephants, with their dexterous trunks and familiarity with manipulating the act of blowing, which is commonly employed for self-comfort and acoustic communication. PMID:26541597

  3. Borders and Legal Criteria for Acquiring Nationality

    Directory of Open Access Journals (Sweden)

    María Elósegui Itxaso

    2008-09-01

    Full Text Available Legal criteria for acquiring nationality are crucial in the integration of persons into society, since they provide access to the right to vote. Until now, the criteria most frequently used are those of ius soli (birth and ius sanguinis (nationality is inherited from the parents, which comply with previous anthropological approaches and which jurists accept without reflection, or consider to be unshakeable traditions.The author’s proposal in this article is to accept that some of these legal criteria should be reformed, though not in an anarchic manner. On one hand, some of the ethnic criteria may be respected, but on the other, the processes of acquiring nationality should be streamlined by accepting the desire of persons wanting to change their nationality on moving to a new country of residence. Meanwhile, we must establish channels of demand for accepting the democratic values and legal system of the welcoming country, as a result of which it would be fair to call for a prior learning period before the rights to nationality and suffrage are granted. The author also adds – and accepts as being a fundamental element – some of Habermas’ inclusion theses, though she stresses that this discourse should be organised into two specific, feasible legal solutions or rather, in a realistic manner.

  4. Focal parenchymal lesions in community-acquired bacterial meningitis in adults: a clinico-radiological study

    Energy Technology Data Exchange (ETDEWEB)

    Katchanov, Juri [Campus Charite Mitte, Charite, Department of Neurology, Berlin (Germany); University Hospital Charite, Campus Benjamin Franklin, Department of Neurology, Berlin (Germany); Siebert, Eberhard; Klingebiel, Randolf [Campus Charite Mitte, Charite, Department of Neuroradiology, Berlin (Germany); Endres, Matthias [Campus Charite Mitte, Charite, Department of Neurology, Berlin (Germany); Charite-Universitaetsmedizin Berlin, Center for Stroke Research Berlin, Berlin (Germany)

    2009-11-15

    Here, we analyzed the frequency, morphological pattern, and imaging characteristics of focal lesions as a consequence of community-acquired bacterial meningitis. We hypothesized that diffusion-weighted imaging combined with contrast-enhanced imaging, serial scanning, and multimodal vascular studies would provide further insight into the pathological basis of such parenchymal lesions in bacterial meningitis. We reviewed clinical and imaging data (i.e., magnetic resonance tomography, magnetic resonance angiography, computed tomography angiography, digital subtraction angiography) of 68 adult patients admitted to our neurological intensive care unit between March 1998 and February 2009 with the diagnosis of community-acquired bacterial meningitis. We identified seven patients with parenchymal lesions. These lesions could be attributed to four morphological patterns: (1) territorial cerebral ischemia, (2) perforating vessels ischemia, (3) ischemia of presumed cardiac origin, and (4) isolated cortical lesions. Whereas the patterns (1) and (2) were associated with vasculopathy of large- and medium-sized vessels (as shown by cerebral vascular imaging), vessel imaging in (3) and (4) did not show abnormal findings. Our study implies that parenchymal lesions in acute bacterial meningitis are mainly ischemic and due to involvement of large-, medium-, and small-sized arteries of the brain. Diffusion-weighted imaging combined with conventional, CT-, or MR-based cerebral angiography revealed the underlying pathophysiological mechanisms in the majority of patients. Furthermore, we detected two patients with isolated bilateral cortical involvement and normal vessel imaging. These lesions might represent ischemia due to the involvement of small pial and intracortical arteries. (orig.)

  5. The influence of physical activity on body image in people with and without acquired mobility disability [Vliv pohybové aktivity na subjektivní vnímání těla u osob se získaným tělesným postižením a bez něj

    Directory of Open Access Journals (Sweden)

    Ziya Koruç

    2011-12-01

    Full Text Available BACKGROUND: Body image in people with physical disability is important, but it has received little attention in the research literature. OBJECTIVE: The aim of the study was to determine whether differences exist between adolescents with acquired mobility disability (AMD and those without AMD regarding body image, and whether physical activity influences these differences. METHODS: Fifty-eight adolescents, aged 16 to 18 years, participated in this study. Half the participants had some form of AMD while the other half were healthy. Body image was evaluated with the Multidimensional Body-Self Relations Questionnaire (MBSRQ before and after 6 weeks of playing darts. A two-way ANOVA was used to analyse the results. RESULTS: At the end of the study, the healthy adolescents scored significantly higher than the AMD group on the subscales of fitness perception, orientation and overall health perception. No interaction was found between disability and exercise on any subscales of the MBSRQ. CONCLUSIONS: The results of this study demonstrate that people with AMD evaluate their health and fitness levels as being lower than healthy adolescents and that they are less concerned with fitness as compared with healthy adolescents. Six weeks of playing darts as a physical activity had no effect on improving the self-perceptions of the AMD group.[VÝCHODISKA: Subjektivní vnímání těla u lidí s tělesným postižením je důležitý aspekt, v odborné literatuře mu však nebylo věnováno příliš pozornosti. CÍLE: Cílem studie bylo stanovit, zda se vyskytují rozdíly mezi adolescenty se získaným tělesným postižením (AMD a adolescenty bez AMD, co se týče subjektivního vnímání těla, a zda tyto rozdíly ovlivňuje pohybová aktivita. METODIKA: Této studie se zúčastnilo padesát osm adolescentů ve věku mezi 16 a 18 lety. Polovina účastníků měla některou z forem AMD, zatímco druhá polovina byla zdravá. Subjektivní vnímání t

  6. Neural Alterations in Acquired Age-Related Hearing Loss

    Directory of Open Access Journals (Sweden)

    Raksha Anand Mudar

    2016-06-01

    Full Text Available Hearing loss is one of the most prevalent chronic health conditions in older adults. Growing evidence suggests that hearing loss is associated with reduced cognitive functioning and incident dementia. In this mini-review, we briefly examine literature on anatomical and functional alterations in the brains of adults with acquired age-associated hearing loss, which may underlie the cognitive consequences observed in this population, focusing on studies that have used structural and functional magnetic resonance imaging, diffusion tensor imaging, and event-related electroencephalography. We discuss structural and functional alterations observed in the temporal and frontal cortices and the limbic system. These neural alterations are discussed in the context of common cause, information-degradation, and sensory-deprivation hypotheses, and we suggest possible rehabilitation strategies. Although we are beginning to learn more about changes in neural architecture and functionality related to age-associated hearing loss, much work remains to be done. Understanding the neural alterations will provide objective markers for early identification of neural consequences of age-associated hearing loss and for evaluating benefits of intervention approaches.

  7. Acquired hepatocerebral degeneration: A case report

    Institute of Scientific and Technical Information of China (English)

    Wei-Xing Chen; Ping Wang; Sen-Xiang Yan; You-Ming Li; Chao-Hui Yu; Ling-Ling Jiang

    2005-01-01

    AIM: Acquired hepatocerebral degeneration (AHD) is an exceptional type of hepatic encephalopathies (HE). It is characterized by neuropsychiatric and extrapyramidal symptomathology similar to that seen in hepatolenticular degeneration (Wilson's disease). In this paper, we report a case of AHD with unusual presenting features.METHODS: A 28-year-old man with AHD was described and the literature was reviewed.RESULTS: The man had a history of HBV-related liver cirrhosis. He was admitted to our hospital with apathy,dysarthria, mild consciousness impairment and extrapyramidal symptoms after hematemesis. By review of the literature,cases with AHD often did not present consciousness impairment. So our case was once diagnosed incorrectly as Wilson's disease.CONCLUSION: AHD is a rare syndrome and its variable clinical manifestations make it difficult to be diagnosed.But we believe that extensive examination and thorough understanding of the disease are beneficial to a correct diagnosis. Moreover, biocoene is effective in treating the case.

  8. Acquired Localized Hypertrichosis Induced by Rivastigmine

    Directory of Open Access Journals (Sweden)

    Adrian Imbernón-Moya

    2016-01-01

    Full Text Available Hypertrichosis is the excessive hair growth in any area of the skin surface. Acquired localized hypertrichosis may be secondary to multiple causes and there is a secondary form due to several drugs, which is usually reversible with discontinuation of the causative agent. Rivastigmine is a reversible and competitive inhibitor of acetylcholinesterase and butyrylcholinesterase used for symptomatic treatment of Alzheimer dementia and Parkinson’s disease. It has an adequate safety profile and cutaneous side effects are unusual. Irritant contact dermatitis, allergic dermatitis, baboon syndrome, and cutaneous rash due to rivastigmine have been reported. We report on a Caucasian 80-year-old male with personal history of Alzheimer’s disease. The patient started therapy with oral rivastigmine one month prior to clinical presentation of localized hypertrichosis on both forearms. Norgalanthamine has been shown to promote hair growth activity via the proliferation of dermal papilla. Acetylcholinesterase inhibitors can induce hair growth.

  9. Hospital Acquired Pneumonia: Issues in Therapy

    Directory of Open Access Journals (Sweden)

    Lionel A Mandell

    1994-01-01

    Full Text Available In December 1992. a meeting was convened in Toronto to develop guidelines for the initial treatment of hospital acquired pneumonia. Issues considered related lo the patient. the possible drugs used for treatment, and the pathogen(s. From the perspective of the patient. the two major issues were the presence or absence of risk factors for specific microbial pathogens and the severity of illness upon clinical presentation, Criteria for defining severly ill patients were developed and are presented in this paper. Drug and pathogen related issues focused on selection of antimicrobial agents thal would provide coverage for the likely pathogens. Concern was also expressed regarding use of aminoglycosides as single-agent treatment of Gram-negative infections in the lung. and the issue of monotherapy versus combination therapy of Pseudomonas aeruginosa infections was discussed. The use of various diagnostic tests was briefly reviewed. including the protected specimen brush and bronchoalveolar lavage. Treatment regimens are presented in tabular format.

  10. Human temporal bone findings in acquired hypothyroidism.

    Science.gov (United States)

    Hald, J; Milroy, C M; Jensen, K D; Parving, A

    1991-11-01

    Histological studies of the auditory organ in patients with acquired hypothyroidism are scarce. Thus the aim of the present study was to examine the temporal bones and the brain in subjects with hypothyroidism. Four temporal bones and two brains from clinically and biochemically hypothyroid subjects were removed and evaluated by light microscopy determine to the morphological changes and deposition of neutral and acid glycosaminoglycans. An audiogram from one of the patients showed a sensorineural hearing loss, which could be ascribed to occupational noise exposure. The study revealed histological changes compatible with age and infectious disease. No accumulation of neutral or acid glycosaminoglycans could be demonstrated in the temporal bones, or in the brains. PMID:1761939

  11. Acquiring Correct Knowledge for Natural Language Generation

    CERN Document Server

    Reiter, E; Sripada, S G; 10.1613/jair.1176

    2011-01-01

    Natural language generation (NLG) systems are computer software systems that produce texts in English and other human languages, often from non-linguistic input data. NLG systems, like most AI systems, need substantial amounts of knowledge. However, our experience in two NLG projects suggests that it is difficult to acquire correct knowledge for NLG systems; indeed, every knowledge acquisition (KA) technique we tried had significant problems. In general terms, these problems were due to the complexity, novelty, and poorly understood nature of the tasks our systems attempted, and were worsened by the fact that people write so differently. This meant in particular that corpus-based KA approaches suffered because it was impossible to assemble a sizable corpus of high-quality consistent manually written texts in our domains; and structured expert-oriented KA techniques suffered because experts disagreed and because we could not get enough information about special and unusual cases to build robust systems. We bel...

  12. Time dysperception perspective for acquired brain injury

    Directory of Open Access Journals (Sweden)

    Federica ePiras

    2014-01-01

    Full Text Available Distortions of time perception are presented by a number of neuropsychiatric disorders. Here we survey timing abilities in clinical populations with acquired brain injuries in key cerebral areas recently implicated in human studies of timing. We purposely analyzed the complex relationship between cognitive and contextual factors involved in time estimation, as to characterize the correlation between timed and other cognitive behaviors in each group. We assume that interval timing is a solid construct to study cognitive dysfunctions following brain injury, as timing performance is a sensitive metric of information processing, while temporal cognition has the potential of influencing a wide range of cognitive processes. Moreover, temporal performance is a sensitive assay of damage to the underlying neural substrate after a brain insult. Further research in neurological and psychiatric patients will definitively answer the question of whether time distortions are manifestations of cognitive and behavioral symptoms of brain damage and definitively clarify their mechanisms.

  13. Multiple myeloma associated with acquired cutis laxa.

    Science.gov (United States)

    Cho, S Y; Maguire, R F

    1980-08-01

    Acquired cutis laxa is a rare disorder characterized by diffuse laxity of the skin and loss of connective tissue support with involvement of the lungs, gastrointestinal tract, pelvic organs, and aorta. The case report presented herein describes a forty-six year old woman with multiple myeloma and cutis laxa. Her history included several severe allergic reactions and the gradual development of lax skin, loss of connective tissue support throughout the body, and emphysema. At autopsy, multiple myeloma, diffuse laxity of the skin, and panacinar emphysema were found. The amount of elastic fiber in the skin, lungs, and aorta was decreased and showed abnormal fragmentation. Results of direct immunofluorescence study demonstrated IgG bound to dermal elastic fibers. Speculation regarding an immunologic etiology of the elastic tissue abnormality is presented herein.

  14. The acquired immunodeficiency syndrome in gay men.

    Science.gov (United States)

    Jaffe, H W; Hardy, A M; Morgan, W M; Darrow, W W

    1985-11-01

    The acquired immunodeficiency syndrome (AIDS) is a major health problem for gay men in the United States. About three fourths of all reported cases have occurred in this population, and the number is projected to double in the next year. In Manhattan and San Francisco, AIDS is now the leading cause of premature mortality in men aged 25 to 44 years who have never married. In a sample of a cohort of gay men enrolled in a San Francisco clinic, 2.7% of the men had the syndrome and 26% had related conditions in 1984. Antibody to human T-lymphotropic virus, type III/lymphadenopathy-associated virus was found in sera from 67% of the men, including 58% of asymptomatic men. Behavioral factors associated with an increased risk of AIDS include large numbers of sexual partners, receptive anal intercourse, and "fisting." The adoption of safer lifestyles is currently the basis of attempts to control the syndrome in gay men. PMID:2996396

  15. Acquired methaemoglobinaemia related to phenazopyridine ingestion.

    Science.gov (United States)

    Shahani, Lokesh; Sattovia, Stacy

    2012-01-01

    Methaemoglobin is an altered state of haemoglobin in which the ferrous ions of haeme are oxidised to the ferric state. This results in increased affinity to the bound oxygen and decreasing its availability to tissues. Most cases of methaemoglobinaemia are acquired, resulting from an increased methaemoglobin formation by various exogenous agents. The authors report an elderly patient presenting to the emergency department with a 1-month history of shortness of breath. Around the same time she had started using over-the-counter (OTC) phenazopyridine tablets for urinary symptoms. The patient was hypoxic and cyanotic; however, lacked evidence of hypoxaemia on the arterial blood gas. The presence of abnormal haemoglobin was suspected and confirmed by elevated levels of methaemoglobin. Phenazopyridine was proposed to be the likely aetiology of the methaemoglobinaemia, which the patient was not aware of. This case highlights the importance of always inquiring the OTC drug use especially in geriatric population. PMID:22987905

  16. [Merits of acquiring ISO15189 accreditation].

    Science.gov (United States)

    Kitagawa, Masami

    2010-01-01

    In Japan, an ISO15189 accreditation system was started in 2005. To date, 47 hospitals have been accredited. In this session, I will present the merits of acquiring accreditation regarding ISO15189 based on our experience. Our hospital has 263 beds. The Clinical Examination Section consists of 12 staff (including 5 part-time workers): 7 in change of sample examination and 5 in charge of physiological examination. The annual number of samples is approximately 150,000. Samples collected on health checkups account for 90%. To improve the quality and service, assessment by third persons has been positively utilized in our hospital. Accreditation regarding ISO9001, ISO14001, ISO27001, privacy mark, hospital function assessment, the functional assessment of "ningen-dock"/health checkup hospitals, labor/hygiene service function assessment, and ISO15189 has been acquired. Patients may not recognize ISO. So, it must be utilized, considering that the acquisition of accreditation is not a goal but a starting point. Furthermore, cost-performance should be improved to achieve utilization-related merits. It is important to not only acquire accreditation but also help clinical staff and patients become aware of some changes/merits. Patients may consult a hospital for the following reasons: confidence in the hospital, and the staffs kind/polite attitudes. Long-term management strategies should be established without pursuing only short-term profits. I will introduce several merits of acquiring accreditation regarding ISO15189. Initially, incidental conditions for bids and appeal points include accreditation regarding ISO15189. Our corporation has participated in some competitive bids regarding health checkup business. In some companies, the bid conditions included ISO acquisition. In our hospital, clinical trials have been positively carried out. For participation in trials, hospitals must pass an institutional examination. However, ISO acquisition facilitates the preparation of

  17. Guidelines for prevention of hospital acquired infections

    Directory of Open Access Journals (Sweden)

    Yatin Mehta

    2014-01-01

    Full Text Available These guidelines, written for clinicians, contains evidence-based recommendations for the prevention of hospital acquired infections Hospital acquired infections are a major cause of mortality and morbidity and provide challenge to clinicians. Measures of infection control include identifying patients at risk of nosocomial infections, observing hand hygiene, following standard precautions to reduce transmission and strategies to reduce VAP, CR-BSI, CAUTI. Environmental factors and architectural lay out also need to be emphasized upon. Infection prevention in special subsets of patients - burns patients, include identifying sources of organism, identification of organisms, isolation if required, antibiotic prophylaxis to be used selectively, early removal of necrotic tissue, prevention of tetanus, early nutrition and surveillance. Immunodeficient and Transplant recipients are at a higher risk of opportunistic infections. The post tranplant timetable is divided into three time periods for determining risk of infections. Room ventilation, cleaning and decontamination, protective clothing with care regarding food requires special consideration. Monitoring and Surveillance are prioritized depending upon the needs. Designated infection control teams should supervise the process and help in collection and compilation of data. Antibiotic Stewardship Recommendations include constituting a team, close coordination between teams, audit, formulary restriction, de-escalation, optimizing dosing, active use of information technology among other measure. The recommendations in these guidelines are intended to support, and not replace, good clinical judgment. The recommendations are rated by a letter that indicates the strength of the recommendation and a Roman numeral that indicates the quality of evidence supporting the recommendation, so that readers can ascertain how best to apply the recommendations in their practice environments.

  18. Does Acquired Hypothyroidism Affect the Hearing Functions?

    Directory of Open Access Journals (Sweden)

    Ayşe Arduç

    2015-12-01

    Full Text Available Purpose: It is well known that congenital hypothyroidism can cause hearing loss. However, conflicting results were found in studies investigating hearing functions in acquired hypothyroidism. Therefore, we evaluated the audiometric findings in patients with acquired hypothyroidism. Material and Method: The study included 58 patients with hypothyroidism and age- and gender-matched 34 healthy controls. Twenty eight (48.27% patients had subclinical hypothyroidism, and 30 (51.73% had obvious hypothyroidism. All subjects had a normal otoscopic examination and tympanometry. Pure tone audiometry at 250, 500, 1000, 2000, 4000, 6000, and 8000 Hertz (Hz was performed in both groups. Blood pressure measurements and the levels of plasma electrolytes, lipids and vitamin B12 were available in all subjects. Results: Hypothyroidism group and control group were similar with respect to systolic and diastolic blood pressures and plasma glucose, lipid, vitamin B12, calcium, sodium, potassium, and chloride levels. Significantly higher audiometric thresholds (dB at 250 (10 (0-45 vs. 5 (0-15, p<0.001 and 500 Hz (10 (0-40 vs. 10 (-5-15, p=0.003 were recorded in hypothyroid patients compared to that in healthy controls. Hearing thresholds at 250 and 500 Hz correlated positively with thyroid-stimulating hormone (TSH, and negatively with free triiodothyronine and free thyroxine. Subclinical hypothyroid patients had a higher hearing threshold at 250 Hz than healthy controls (p=0.001. Discussion: Our study demonstrated that hearing ability decreases in hypothyroidism, even in subclinical hypothyroidism. The changes in TSH and thyroid hormone levels seem to be directly related to the hearing loss in this population of patients.

  19. Immunosuppression for acquired hemophilia A : results from the European Acquired Haemophilia Registry (EACH2)

    NARCIS (Netherlands)

    Collins, Peter; Baudo, Francesco; Knoebl, Paul; Levesque, Herve; Nemes, Laszlo; Pellegrini, Fabio; Marco, Pascual; Tengborn, Lilian; Huth-Kuehne, Angela; Aspoeck, Gerold; Heistinger, Max; Knobl, Paul; Makipernaa, Anne; Andre, Helene; Aouba, A; Bellucci, Sylvia; Beurrier, Philippe; Borg, Jeanne Yvonne; Darnige, Luc; Devignes, Jean; dOiron, Roseline; Gautier, Philippe; Gay, Valerie; Girault, Stephane; Gruel, Yves; Guerin, Viviane; Hezard, Nathalie; Khellaf, Mehdi; Koenig, Martial; Levesque, Herve; Lifermann, Francois; Marlu, Raphael; Ninet, J.; Peynet, Jocelyne; Quemeneur, Thomas; Rothschild, Chantal; Schleinitz, Nicolas; Sigaud, Marianne; Trouillier, Sebastien; Voisin, Sophie; Giebl, Andreas; Holstein, Katharina; Huth-Kuhne, Angela; Loreth, Ralph M.; Steigerwald, Udo; Tiede, Andreas; Theodossiades, George; Nemes, Laszlo; Radvanyi, Gaspar; Schlammadinger, Agota; Barillari, Giovanni; Pasca, Samantha; Baudo, Francesco; Caimi, T.; Contino, L.; D'Angelo, Armando; Crippa, Luciano; Fattorini, Annalisa; Di Minno, Giovanni; Cerbone, Anna Maria; Di Minno, Matteo Nicola Dario; D'inca, Marco; Falanga, Anna; Maggioni, Anna; Lerede, Teresa; Franchini, Massimo; Gaidano, Gianluca; De Paoli, Lorenzo; Gamba, Gabriella; Ghirardi, Raffaele; Girotto, Mauro; Tasca, Delios; Grandone, Elvira; Tiscia, Giovanni; Imberti, Davide; Iorio, Alfonso; Landolfi, Raffaele; Di Gennaro, Leonardo; Novarese, Linda; Mariani, Guglielmo; Lapecorella, Mario; Marietta, Marco; Pedrazzi, Paola; Mazzucconi, Maria Gabriella; Santoro, Cristina; Morfini, Massimo; Linari, Silvia; Moratelli, Stefano; Paolini, Rossella; Piseddu, Gavino; Poggio, Renzo; Pogliani, Enrico; Carpenedo, Monica; Remiddi, Chiara; Santagostino, Elena; Mancuso, Maria Elisa; Santoro, Rita; Papaleo, Giuseppina; Schinco, Piercarla; Borchiellini, Alessandra; Valeri, Federica; Scortechini, Anna Rita; Siragusa, Sergio; Sottilotta, Gianluca; Squizzato, Alessandro; Tagariello, Giuseppe; Sartori, Roberto; Tagliaferri, Anna Rita; Di Perna, Caterina; Rivolta, Gianna Franca; Testa, Sophie; Paoletti, Oriana; Toschi, Vincenzo; Zanon, Ezio; Brandolin, Barbara; Hamulyak, Karly; Kamphuisen, Pieter; Laros-van Gorkom, Britta; Leebeek, Frank W.G.; Marten, Nijziel; Novakova, Irena; Schutgens, Roger; van der Linden, P.W.G; van Esser, Joost; van der Meer, J.; Ypma, Paula; Campos, Manuel; Aguilar, Carlos; Altisent, Carmen; Bermejo, Nuria; Del Campo, Raquel; Ferreiro Arguelles, M.; Gonzalez Boullosa, Rosario; Gutierrez Pimentel, Maria Jose; Jimenez-Yuste, Victor [No Value; Jose-Felix, Lucia; Marco, Pascual; Mingot, Maria Eva; Perez Garrido, Rosario; Perez Gonzale, Noelia z; Prieto Garcia, Manuel; Rodriguez-Huerta, Ana Maria; Maranon, HGUG [No Value; Sedano, Carmen; Tolosa Munoz, Alexandra; Baghaei, Fariba; Tengborn, Lilian; Boehlen, Francoise; Korte, Wolfgang; Chowdary, Pratima; Collins, Peter; Evans, Gillian; Pavord, Suzanne; Rangarajan, Savita; Wilde, Jonathan

    2012-01-01

    Acquired hemophilia A (AHA) is an autoimmune disease caused by an autoantibody to factor VIII. Patients are at risk of severe and fatal hemorrhage until the inhibitor is eradicated, and guidelines recommend immunosuppression as soon as the diagnosis has been made. The optimal immunosuppressive regim

  20. 48 CFR 970.4102 - Acquiring utility services.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Acquiring utility services... SUPPLEMENTARY REGULATIONS DOE MANAGEMENT AND OPERATING CONTRACTS Acquisition of Utility Services 970.4102 Acquiring utility services....

  1. Late-onset Ito's nevus: an uncommon acquired dermal melanocytosis.

    Science.gov (United States)

    Mataix, Javier; López, Norberto; Haro, Rosario; González, Elena; Angulo, Jorge; Requena, Luis

    2007-08-01

    Dermal melanocytoses comprise a variety of congenital and acquired conditions characterized by a sparse population of intradermal dendritic, variably pigmented, spindle-shaped melanocytes. While Mongolian spot, Ota's and Ito's nevi are usually present at birth or appear around puberty; acquired dermal melanocytoses that appear in adult life are extremely rare. They include the facial lesions of acquired bilateral nevus of Ota-like macules, also named Hori's nevus, and the acquired unilateral nevus of Ota, also known as Sun's nevus. Uncommon extrafacial examples of acquired dermal melanocytoses include lesions involving upper extremities, wrist, back, lower extremities and dorsal aspects of the hands and feet. They are more prevalent among Asian women. In general, dermal melanocytoses are rare lesions in Caucasian patients and acquired variants are exceedingly uncommon. We report a rare example of acquired Ito's nevus that appeared in a Caucasian elderly woman and review the literature about acquired dermal melanocytoses.

  2. Acquiring Control in Emerging Markets: Evidence from the Stock Market

    OpenAIRE

    Anusha Chari; Paige P. Ouimet; Tesar, Linda L.

    2004-01-01

    When firms from developed markets acquire firms in emerging markets, market-capitalization-weighted monthly joint returns show a statistically significant increase of 1.8%. Panel data estimations suggest that the value gains from cross-border M&A transactions stem from the transfer of majority control from emerging-market targets to developed market acquirers' joint returns range from 5.8% to 7.8% when majority control is acquired. Announcement returns for acquirer and target firms estimate t...

  3. Mucocutaneous manifestations of acquired hypoparathyroidism: An observational study

    OpenAIRE

    Somenath Sarkar; Modhuchanda Mondal; Kapildev Das; Arpit Shrimal

    2012-01-01

    Hypoparathyroidism is a disorder of calcium and phosphorus metabolism due to decreased secretion of parathyroid hormone. Hypoparathyroidism can be hereditary and acquired. Acquired hypoparathyroidism usually occurs following neck surgery (thyroid surgery or parathyroid surgery). Along with systemic manifestations, hypoparathyroidism produces some skin manifestations. Lack of study regarding mucocutaneous manifestations of acquired hypoparathyroidism prompted us to undertake this study. To eva...

  4. Preschoolers Acquire General Knowledge by Sharing in Pretense

    Science.gov (United States)

    Sutherland, Shelbie L.; Friedman, Ori

    2012-01-01

    Children acquire general knowledge about many kinds of things, but there are few known means by which this knowledge is acquired. In this article, it is proposed that children acquire generic knowledge by sharing in pretend play. In Experiment 1, twenty-two 3- to 4-year-olds watched pretense in which a puppet represented a "nerp" (an unfamiliar…

  5. New image measurements of the gravity wave propagation characteristics from a low latitude Indian station

    Directory of Open Access Journals (Sweden)

    M. Sivakandan

    2015-08-01

    Full Text Available The image observations of mesospheric O(1S 558 nm have been performed from a low latitude Indian station, Gadanki (13.5° N; 79.2° E using a CCD based all sky camera system. Based on three years (from year 2012 to the year 2014 of image data during March–April, we characterize the small scale gravity wave properties. We noted 50 strong gravity wave event and 19 ripple events to occur. The horizontal wavelengths of the gravity waves are found to vary from 12 to 42 km with the phase velocity ranging from 20 to 90 km. In most cases, these waves were propagating towards north with only a few occasions of southward propagation. The outgoing longwave radiation data suggest that lower atmospheric convection was most possible reason for the generation of the waves observed in the airglow data.

  6. New approach for super-resolution imaging of NV-nanodiamonds

    Science.gov (United States)

    Arai, Keigo; Le Sage, David; Bar-Gill, Nir; Belthangady, Chinmay; Glenn, David; Linh Pham, My; Zhang, Huiliang; Walsworth, Ronald

    2012-06-01

    We describe a new approach for super-resolution imaging of nanodiamonds (NDs) containing NV centers. The random orientation of NDs in a static magnetic field allow each ND to be distinguished by the NV ESR Zeeman shift and spin-state-dependent fluorescence rate. We exploit this behavior as a photo-switch such that adjacent NDs emit fluorescence sequentially in time. Post-analysis of a series of images at each ESR resonance frequency can localize individual NDs with sub-wavelength resolution. This technique has the advantage of being compatible with CCD-based wide-field microscopy, and involves significantly less laser intensity and experimental complexity than STED-based approaches.

  7. Relapsing malaria infection acquired in Kenya.

    OpenAIRE

    Patterson, J E; Bia, F. J.; Miller, K.; McPhedran, P.

    1987-01-01

    An American physician-traveler to East Africa presented with manifestations of cerebral malaria and was treated with intravenous quinidine for chloroquine-resistant falciparum malaria. He later relapsed with Plasmodium ovale infection, despite previous primaquine therapy. Treatment of chloroquine-resistant malaria is discussed. The difficulty in diagnosing P. ovale infections and the predominance of this malaria species over P. vivax in East Africa are reviewed. Images FIG. 1 FIG. 2 FIG. 3

  8. Epilepsy, Acquired Aphasia with Focal Cortical Dysplasia

    Directory of Open Access Journals (Sweden)

    Girija A.S

    1999-01-01

    Full Text Available A six year old boy having complex partial seizures with secondary generalization of four months duration developing isolated expressive dysphasia, later progressing to global aphasia is being reported. His awake EEG showed a left temporal spike wave discharge and sleep EEG showed continuous spike and ware discharges. MR imaging demonstrated focal cortical dysplasia in the left frontal and opercular region, a combination that has not been reported earlier.

  9. Acquired hemophilia a successfully treated with rituximab.

    Science.gov (United States)

    D'Arena, Giovanni; Grandone, Elvira; Di Minno, Matteo Nicola Dario; Musto, Pellegrino; Di Minno, Giovanni

    2015-01-01

    Acquired hemophilia A (AHA) is a rare bleeding disorder due to the development of specific autoantibodies against factor VIII. The anti-CD20 monoclonal antibody Rituximab has been proven to be effective in obtaining a long-term suppression of inhibitors of AHA, besides other immunosuppressive standard treatments. Here we describe a case of idiopathic AHA in a 60-year old man successfully treated with rituximab. He showed a complete clinical response with a normalization of clotting parameters after 5 weekly courses of rituximab given at a dose of 375 mg/sqm., but after stopping rituximab, an initial worsening of coagulation parameters induced the addition of 3 further courses. At present, the patient is in complete clinical and hematological remission after 200 days. This case confirms that Rituximab may be a safe and useful tool to treat AHA and, a prolonged administration can overcome the initial resistance. However, the precise position of this drug in the therapeutic strategy (first or second-line, alone or in combination with other drugs) remains to be established and warrants further investigation. PMID:25745551

  10. Acquired Hemophilia A successfully treated with rituximab

    Directory of Open Access Journals (Sweden)

    Giovanni D'Arena

    2015-02-01

    Full Text Available Acquired hemophilia A (AHA is a rare bleeding disorder due to the development of specific autoantibodies against factor VIII. The anti-CD20 monoclonal antibody Rituximab has been proven to be effective in  obtaining a long-term suppression of inhibitors of AHA,  besides other immunosuppressive standard treatments. Here we describe a case of idiopathic AHA in a 60-year old man successfully treated with rituximab. He showed a complete clinical response with  a normalization of clotting  parameters after 5 weekly courses of rituximab given at a dose of 375 mg/sqm. , but after stopping rituximab, an initial worsening of coagulation  parameters  induced the addition of 3 further courses. At present, the patient is in complete clinical and hematological remission after 200 days.  This case confirms that Rituximab may be a safe and useful tool to treat AHA and, a prolonged administration can overcome the initial resistance. However, the precise position of this drug in the therapeutic strategy (first or second-line, alone or in combination with other drugs remains to be established and warrants further investigation.

  11. Acquired prosopagnosia: structural basis and processing impairments.

    Science.gov (United States)

    Davies-Thompson, Jodie; Pancaroglu, Raika; Barton, Jason

    2014-01-01

    Cognitive models propose a hierarchy of parallel processing stages in face perception, and functional neuroimaging shows a network of regions involved in face processing. Reflecting this, acquired prosopagnosia is not a single entity but a family of disorders with different anatomic lesions and different functional deficits. One classic distinction is between an apperceptive variant, in which there is impaired perception of facial structure, and an associative/amnestic variant, in which perception is relatively intact, with subsequent problems matching perception to facial memories, because of either disconnection or loss of those memories. These disorders also have to be distinguished from people-specific amnesia, a multimodal impairment, and prosop-anomia, in which familiarity with faces is preserved but access to names is disrupted. These different disorders can be conceived as specific deficits at different processing stages in cognitive models, and suggests that these functional stages may have distinct neuroanatomic substrates. It remains to be seen whether a similar anatomic and functional variability is present in developmental prosopagnosia.

  12. In vivo models of cortical acquired epilepsy.

    Science.gov (United States)

    Chauvette, Sylvain; Soltani, Sara; Seigneur, Josée; Timofeev, Igor

    2016-02-15

    The neocortex is the site of origin of several forms of acquired epilepsy. Here we provide a brief review of experimental models that were recently developed to study neocortical epileptogenesis as well as some major results obtained with these methods. Most of neocortical seizures appear to be nocturnal and it is known that neuronal activities reveal high levels of synchrony during slow-wave sleep. Therefore, we start the review with a description of mechanisms of neuronal synchronization and major forms of synchronized normal and pathological activities. Then, we describe three experimental models of seizures and epileptogenesis: ketamine-xylazine anesthesia as feline seizure triggered factor, cortical undercut as cortical penetrating wound model and neocortical kindling. Besides specific technical details describing these models we also provide major features of pathological brain activities recorded during epileptogenesis and seizures. The most common feature of all models of neocortical epileptogenesis is the increased duration of network silent states that up-regulates neuronal excitability and eventually leads to epilepsy.

  13. Statistical image processing and multidimensional modeling

    CERN Document Server

    Fieguth, Paul

    2010-01-01

    Images are all around us! The proliferation of low-cost, high-quality imaging devices has led to an explosion in acquired images. When these images are acquired from a microscope, telescope, satellite, or medical imaging device, there is a statistical image processing task: the inference of something - an artery, a road, a DNA marker, an oil spill - from imagery, possibly noisy, blurry, or incomplete. A great many textbooks have been written on image processing. However this book does not so much focus on images, per se, but rather on spatial data sets, with one or more measurements taken over

  14. Interpolation Technique in Computed Tomography Image Visualisation(Short Communication)

    OpenAIRE

    Asha Tripathi; P. K. Khatri; G. L. Baheti; K. C. Songara

    2002-01-01

    An interpolation technique has been developed for generation of enlarged dataset from a limited one-dimesional acquired dataset for improving the image quality in quick-scan tomography. The effectiveness of the technique has been tested using data acquired from the first-generation. The CT images generated using this technique have been compared with the CT images generated from the acquired dataset for the same number of projections. The image quality has been improved on account of (...

  15. SPOT Controlled Image Base 10 meter

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — SPOT Controlled Image Base 10 meter (CIB-10) is a collection of orthorectified panchromatic (grayscale) images. The data were acquired between 1986 and 1993 by the...

  16. Cytomegalovirus retinitis associated with acquired immunodeficiency syndrome

    Institute of Scientific and Technical Information of China (English)

    GENG Shuang; YE Jun-jie; ZHAO Jia-liang; LI Tai-sheng; HAN Yang

    2011-01-01

    Background Cytomegalovirus (CMV) retinitis is the most severe intraocular complication that results in total retinal destruction and loss of visual acuity in patients with acquired immunodeficiency syndrome (AIDS). This study aimed to investigate the fundus characteristics, systemic manifestations and therapeutic outcomes of CMV retinitis associated with AIDS.Methods It was a retrospective case series. CMV retinitis was present in 39 eyes (25 patients). Best corrected visual acuities, anterior segment, fundus features, fundus fluorescence angiography (FFA) and CD4+ T-lymphocyte counts of the patients with CMV retinitis associated with AIDS were analyzed. Intravitreal injections of ganciclovir (400 μg) were performed in 4 eyes (2 patients).Results Retinal vasculitis, dense, full-thickness, yellow-white lesions along vascular distribution with irregular granules at the border, and hemorrhage on the retinal surface were present in 28 eyes. The vitreous was clear or mildly opaque.Late stage of the retinopathy was demonstrated in 8 eyes characterized as atrophic retina, sclerotic and attenuated vessels, retinal pigment epithelium (RPE) atrophy, and optic nerve atrophy. Retinal detachment was found in 3 eyes. The average CD4+ T-lymphocyte count in peripheral blood of the patients with CMV retinitis was (30.6±25.3) ×106/L (range,(0-85) × 106/L). After intravitreal injections of ganciclovir, visual acuity was improved and fundus lesions regressed.Conclusions CMV retinitis is the most severe and the most common intraocular complication in patients with AIDS. For the patients with yellow-white retinal lesions, hemorrhage and retinal vasculitis without clear cause, human immunodeficiency virus (HIV) serology should be performed. Routine eye examination is also indicated in HIV positive patients.

  17. Thymus involution in the acquired immunodeficiency syndrome.

    Science.gov (United States)

    Grody, W W; Fligiel, S; Naeim, F

    1985-07-01

    Acquired immunodeficiency syndrome (AIDS) is a severe disorder of unknown etiology and pathogenesis, predominantly affecting homosexual males and other high-risk groups and characterized by profound alterations in T-lymphocyte function. The authors have examined thymus tissue from 14 patients who died of AIDS and compared the results with findings in five control groups: healthy age-matched controls, elderly individuals, patients with chronic or debilitating illnesses other than AIDS, infants with conditions causing "stress atrophy," and patients with myasthenia gravis. The AIDS group included 11 homosexual males, 1 Haitian, 1 homosexual who was also a drug abuser, and a 10-month-old infant believed to have contracted AIDS following blood transfusion. All the AIDS cases showed marked thymus involution with severe depletion of both lymphocytes and epithelial elements. The latter component consisted primarily of thin cords and nests of primitive-appearing epithelial cells that could be defined by positive immunohistochemical staining for keratin. Many cases showed a variable plasma cell infiltration, and the majority exhibited distinct vascular changes in the form of hyalinization and/or onion-skin patterns, primarily in the adventitia. Most striking of all was the marked paucity of Hassall's corpuscles; four patients had none at all, while in the other ten patients all the Hassall's corpuscles were calcified. These changes were far more extensive than those seen in any of the control groups, which retained most of their complement of Hassall's corpuscles even in the face of marked overall involution. The physiologic function of Hassall's corpuscles is not known, but recent immunohistochemical studies have implicated them in the synthesis of "facteur thymique serique" (FTS, thymulin) and other thymic hormones known to play a role in regulating T-helper and suppressor cell activity. It is conceivable that the extensive destruction of Hassall's corpuscles observed in

  18. Imaging life

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    Molecular imaging is a new science bridging together molecular biology and in vivo imaging. The considerable progress made in recent years by non invasive imaging instruments, probes, image analysis,biological models and mathematical modelling have now made it possible to visualize gene expression in vivo. significant advances in many molecular imaging modalities now allow the scientists to reach unprecedented sensitivities for non invasive detection of molecules in living individuals. This progress is largely fertilizing medical imaging and clinical practice. With these technological developments and the capacity to transfer research data directly into clinical applications, molecular imaging has become the way to tackle disease diagnosis and treatment following the rules of the three Ps: precocious, precise and predictive. This is essential to validate in the context of living organisms the targets and drugs designed by genome data mining and in vitro gene expression analysis through methods that are both non invasive and repeatable; acquire fundamental knowledge about the patterns of gene expression in normal tissues and define the changes in specific gene expression during the course of disease; design and develop drugs targeting disease related gene expression; allow precise evaluation of new treatments and new drugs that are required for progress in disease management through reliable measures of the disease burden. (author)

  19. Progressive multifocal leukoence-phalopathy presenting as homonymous hemianopia in a patient with acquired immunodeficiency syndrome

    Directory of Open Access Journals (Sweden)

    Amit Pandey

    2012-01-01

    Full Text Available We present a case of a Human Immunodeficiency Virus (HIV positive patient who was referred for retinal evaluation to rule out ophthalmic manifestations of Acquired Immunodeficiency Syndrome (AIDS. She complained of some disturbance in vision in both eyes. Fundus examination showed no abnormality. Perimetry, done to rule out optic nerve pathology, showed a left homonymous hemianopia. Magnetic Resonance Imaging (MRI scan showed features of Progressive Multifocal Leukoencephalopathy (PML. She had no other neurological symptoms or signs.

  20. Action observation and acquired motor skills: An fMRI study with expert dancers

    OpenAIRE

    Calvo-Merino, B.; Glaser, D.E.; Grezes, J.; Passingham, R. E.; Haggard, P

    2005-01-01

    When we observe someone performing an action, do our brains simulate making that action? Acquired motor skills offer a unique way to test this question, since people differ widely in the actions they have learned to perform. We used functional magnetic resonance imaging to study differences in brain activity between watching an action that one has learned to do and an action that one has not, in order to assess whether the brain processes of action observation are modulated by the expertise a...

  1. Residual fMRI sensitivity for identity changes in acquired prosopagnosia

    OpenAIRE

    Fox, Christopher J; Giuseppe eIaria; Duchaine, Bradley C.; Barton, Jason J.S.

    2013-01-01

    While a network of cortical regions contribute to face processing, the lesions in acquired prosopagnosia are highly variable, and likely result in different combinations of spared and affected regions of this network. To assess the residual functional sensitivities of spared regions in prosopagnosia, we designed a rapid event-related functional magnetic resonance imaging (fMRI) experiment that included pairs of faces with same or different identities and same or different expressions. By meas...

  2. Evolution and sequlae of acquired lobar emphysema in a premature infant with cronic lung disease

    International Nuclear Information System (INIS)

    The evolution of acquired lobar emphysemain a premature infant with cronic pulmonary disease was demonstrated by serial radiological examinations using multiple imaging methods including plain radiography, serial computed tomography and radionuclide studies. Long term clinical and radiological followup is presented. The value of computed tomography in the evolution of patient is emphasized. The literature on the patho-physiological mechanism of the disease is reviewed. (author)

  3. Feasibility and Initial Performance of Simultaneous SPECT-CT Imaging Using a Commercial Multi-Modality Preclinical Imaging System

    OpenAIRE

    Osborne, Dustin R.; Derek W. Austin

    2015-01-01

    Multi-modality imaging provides coregistered PET-CT and SPECT-CT images; however such multi-modality workflows usually consist of sequential scans from the individual imaging components for each modality. This typical workflow may result in long scan times limiting throughput of the imaging system. Conversely, acquiring multi-modality data simultaneously may improve correlation and registration of images, improve temporal alignment of the acquired data, increase imaging throughput, and benefi...

  4. Imaging spectroscopy with the atomic force microscope

    OpenAIRE

    Baselt, David R.; Baldeschwieler, John D.

    1994-01-01

    Force curve imaging spectroscopy involves acquiring a force-distance curve at each pixel of an atomic force microscope image. Processing of the resulting data yields images of sample hardness and tip-sample adhesion. These images resemble Z modulation images and the sum of forward and reverse friction images, respectively, and like them exhibit a number of potentially misleading contrast mechanisms. In particular, XY tip motion has a pronounced effect on hardness images and the meniscus force...

  5. An experimental study on the readability of digital images in the furcal bone defects

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Hyung Wuk; Hwang, Eui Hwan; Lee, Sang Rae [Kyunghee University College of Medicine, Seoul (Korea, Republic of)

    2003-06-15

    To evaluate and compare the efficacy of digital radiographic images in the detection of bone loss at the bifurcation area of the mandibular first molar with traditional film-based periapical radiographs. One dried human mandible with minimal periodontal bone loss around the first molar was selected and an artificial alveolar bone defect at the bifurcation area was serially prepared over 18 steps. Images were taken using a direct CCD-based system and with F-speed periapical films. The images were evaluated by seven interpreters (3 radiologists, 3 periodontologists, and 1 general dentist) using a 5-point confidence rating scale. The readability of both periapical radiographs and digital image increased as the size of the artificial lesion and exposure time increased (p<0.05). Periapical radiographs offered greater readability of smaller bone defects than digital images, and the coefficient of variation of mean score between periapical radiographs and digital images showed a significant difference. The experimental results indicate that a significant difference in the coefficient of variation of mean score exists between periapical radiographs and digital images, and that traditional film-based periapical images offer greater readability of smaller bone defects than digital images can presently offer.

  6. Acquiring and maintaining competency in gastrointestinal endoscopy.

    Science.gov (United States)

    Dubé, Catherine; Rostom, Alaa

    2016-06-01

    In recent years, an important transformation has taken place in the field of gastrointestinal endoscopy training. Two important movements have helped initiate this transformation: patient centered quality and competency based training. Patient centered quality in endoscopy became an important focus for colorectal cancer screening programs, as it was acknowledged that colonoscopy services played a central role in the outcomes of screening. This prompted the need to close the quality loop through the development of innovative endoscopist training and upskilling programs. As well, the importance of leadership skills and leadership training was highlighted as a key factor in effective quality improvement. Competency-based training depends on well-defined goals of training and on the regular documentation and review of the learner's progress. This is facilitated by objective assessment and performance enhancing feedback, enabled by measurement tools that can provide a quantitative or qualitative assessment and identify areas in need of further development. Simulators and scope imagers can aid the acquisition of technical skills, particularly in the novice phase. These important advances in our evolving concepts around endoscopy training have also raised many questions, highlighting important knowledge gaps which, we hope, will be addressed in coming years. PMID:27345643

  7. The case of Geely acquiring Volvo Car : A study on low brand equity acquiring high brand equity

    OpenAIRE

    Zheng, Xiaoshu; Shi, Yuan

    2013-01-01

    Much previous research has studied high brand equity acquiring high brand equity or high brand equity acquiring low brand equity. However, very little research has been conducted to understand how that low brand equity acquiring high brand equity changes the low brand equity especially in China. This paper is on the case of Geely Group acquiring Volvo Car which was a typical acquisition of a high brand equity company by a low brand equity company. The aim of the paper is to verify whether thi...

  8. PATHOGENETIC MECHANISMS OF CHRONIC ACQUIRED TOXOPLASMOSIS

    Directory of Open Access Journals (Sweden)

    Kotsyna S.S.

    2015-05-01

    Full Text Available Introduction. Toxoplasma gondii is an intracellular protozoan that infects approximately one-third of the world’s population. Infection in human generally occurs through consuming food or drink contaminated with oocysts and tissue cysts from undercooked meat. Although latent infection with Toxoplasma gondii is among the most prevalent of human infections, it has been generally assumed that, except for congenital transmission, it is asymptomatic. Different conditions such as, number of parasite, virulence of the organism, genetic background, sex, and immunological status seem to affect the course of infection The demonstration that Toxoplasma infections can alter behavior, reproductive function in patients has led to a reconsideration of this assumption. During chronic acquired toxoplasmosis (САT identified the regularities of changes in the ratio of the immune system and the basal levels of sex hormones available informative methods, which made it possible to evaluate the severity of the flow chart and predict treatment outcome without resorting to complex research methods. Found that the host-parasite relationships and clinical manifestations of chronic toxoplasmosis depend largely on protective and adaptive responses and compensatory abilities of the human body. Material & methods. 112 patients attended in the 6 Department of Kharkiv Regional Infectious Diseases Hospital №22 (Department of Medical Parasitology and Tropical Diseases of Kharkiv Medical Academy of Postgraduate Education, in Kharkiv, Ukraine were enrolled in the study. Forty four patients (39,3±4,6% were male and sixty eight (60,7±4,6% were female. The age of the patients was 18 till 72 years. Results & discussion. All of 112 CAT patients had subjective clinical symptoms in various combinations: increased fatigue 99,1 ± 0,9%, headache and tiredness 95,5 ± 1,9%, pain in the liver 88,4 ± 3,1%, bitter taste in the mouth 93,8 ± 2,2%, muscle pain 81,3 ± 3,7% and joint pain

  9. Significance of acquired diverticular disease of the vermiform appendix

    DEFF Research Database (Denmark)

    Kallenbach, Klaus; Hjorth, Sofie Vetli; Engel, Ulla;

    2012-01-01

    To assess the prevalence of acquired diverticulum of the appendix (DA), including incipient forms and its possible significance as a marker of local/regional neoplasms.......To assess the prevalence of acquired diverticulum of the appendix (DA), including incipient forms and its possible significance as a marker of local/regional neoplasms....

  10. The challenge of retaining customers acquired with free trials

    NARCIS (Netherlands)

    Datta, H.; Foubert, B.; van Heerde, H.J.

    2015-01-01

    Many service firms acquire customers by offering free-trial promotions. A crucial challenge is to retain customers acquired with these free trials. To address this challenge, firms need to understand how free-trial customers differ from regular customers in terms of their decision making to retain t

  11. Clinical aspects of acquired aphasia and dysarthria in childhood

    NARCIS (Netherlands)

    H.R. van Dongen (Hugo)

    1988-01-01

    textabstractFor the last decade, it has been a common clinical belief that the prognosis of acquired childhood aphasia is good. However, our own clinical experiences were rather conflicting on this point. As a consequence, we re-examined all the children (15) with an acquired aphasia who in a period

  12. 33 CFR 211.2 - Authority to acquire real estate.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Authority to acquire real estate..., DEPARTMENT OF DEFENSE REAL ESTATE ACTIVITIES OF THE CORPS OF ENGINEERS IN CONNECTION WITH CIVIL WORKS PROJECTS Real Estate; General § 211.2 Authority to acquire real estate. (a) Congressional...

  13. 26 CFR 1.472-7 - Inventories of acquiring corporations.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 6 2010-04-01 2010-04-01 false Inventories of acquiring corporations. 1.472-7 Section 1.472-7 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Inventories § 1.472-7 Inventories of acquiring corporations....

  14. 26 CFR 1.471-9 - Inventories of acquiring corporations.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 6 2010-04-01 2010-04-01 false Inventories of acquiring corporations. 1.471-9 Section 1.471-9 Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME TAX (CONTINUED) INCOME TAXES Inventories § 1.471-9 Inventories of acquiring corporations....

  15. Normalizing and converting image DC data using scatter plot matching

    Science.gov (United States)

    Remote sensing image data from sources such as Landsat or airborne multispectral digital cameras are typically in the form of digital count (DC) values. To compare images acquired by the same sensor system on different dates, or images acquired by different sensor systems, it is necessary to correct...

  16. Imaging and Analytics: The changing face of Medical Imaging

    Science.gov (United States)

    Foo, Thomas

    There have been significant technological advances in imaging capability over the past 40 years. Medical imaging capabilities have developed rapidly, along with technology development in computational processing speed and miniaturization. Moving to all-digital, the number of images that are acquired in a routine clinical examination has increased dramatically from under 50 images in the early days of CT and MRI to more than 500-1000 images today. The staggering number of images that are routinely acquired poses significant challenges for clinicians to interpret the data and to correctly identify the clinical problem. Although the time provided to render a clinical finding has not substantially changed, the amount of data available for interpretation has grown exponentially. In addition, the image quality (spatial resolution) and information content (physiologically-dependent image contrast) has also increased significantly with advances in medical imaging technology. On its current trajectory, medical imaging in the traditional sense is unsustainable. To assist in filtering and extracting the most relevant data elements from medical imaging, image analytics will have a much larger role. Automated image segmentation, generation of parametric image maps, and clinical decision support tools will be needed and developed apace to allow the clinician to manage, extract and utilize only the information that will help improve diagnostic accuracy and sensitivity. As medical imaging devices continue to improve in spatial resolution, functional and anatomical information content, image/data analytics will be more ubiquitous and integral to medical imaging capability.

  17. Hospital-acquired and Community-acquired Uropathogens; Modelling of Infection

    Directory of Open Access Journals (Sweden)

    Aija ?ilevi?a

    2005-12-01

    Full Text Available Urinary tract infections are among the most common human infections. They may be community-acquired or nosocomial, and caused by a variety of microorganisms. In the present study, we analysed more than 4000 urine samples collected from in-patients and outpatients, and registered the differences in the etiological spectrum of agents. The most widespread uropathogens are gram-negative rods, from them E. coli, Klebsiella spp. and the non-fermentive genus Pseudomonas. Women are more intensively affected by E. coli. From gram-positive cocci, the leading agents are coagulase negative Staphylococci, followed by S. aureus. No differences were registered between the genders. Polyresistance among gram-negative uropathogens is high.

  18. Hydrocephalus is a rare outcome in community-acquired bacterial meningitis in adults

    DEFF Research Database (Denmark)

    Bodilsen, Jacob; Schønheyder, Henrik Carl; Nielsen, Henrik I

    2013-01-01

    BACKGROUND: Community-acquired bacterial meningitis (CABM) continues to have a high mortality rate and often results in severe sequelae among survivors. Lately, an increased effort has been focused on describing the neurological complications of meningitis including hydrocephalus. To aid in this ......BACKGROUND: Community-acquired bacterial meningitis (CABM) continues to have a high mortality rate and often results in severe sequelae among survivors. Lately, an increased effort has been focused on describing the neurological complications of meningitis including hydrocephalus. To aid...... in this field of research we set out to ascertain the risk and outcome of hydrocephalus in patients with community-acquired bacterial meningitis (CABM) in North Denmark Region. METHODS: We conducted a retrospective population-based cohort study of CABM cases above 14 years of age. Cases diagnosed during a 13......-year period, 1998 through 2010, were identified in a laboratory register and data were acquired through patient records. Cases not confirmed by culture met other strict inclusion criteria. The diagnosis of hydrocephalus relied upon the radiologists' reports on cranial imaging. Outcome was graded...

  19. Clinical data analysis of 19 cases of community-acquired adenovirus pneumonia in immunocompetent adults.

    Science.gov (United States)

    Yu, Hong-Xia; Zhao, Mao-Mao; Pu, Zeng-Hui; Wang, Yun-Qiang; Liu, Yan

    2015-01-01

    The aim of this study was to investigate the characteristics of clinical manifestations, laboratory tests and imaging changes of community-acquired adenovirus pneumonia in immunocompetent adults. A retrospective study was performed on 19 adult community-acquired adenovirus pneumonia cases in Yantai, whereby the clinical data were collected and analyzed. Of 19 cases, 14 (73.68%) had fever and 17 (89.47%) had cough symptoms. Moreover, 14 cases (73.68%) had normal white blood cell counts, while 11 cases (57.89%) exhibited a reduction in lymphocyte proportion. Among the 19 cases, 17 cases exhibited lesions in a single lung, while 2 cases involved bilateral lungs. The lesions predominantly exhibited ground glass-like changes. The clinical manifestations of adult community-acquired adenovirus pneumonia patients with normal immune functions were mild, with such presenting symptoms as fever, cough, and sputum; most patients did not exhibit high levels of white blood cells or low lymphocyte counts, and the imaging features (ground glass-like effusion) were indicative of single-lung involvement.

  20. Acquiring 4D thoracic CT scans using a multislice helical method

    International Nuclear Information System (INIS)

    Respiratory motion degrades anatomic position reproducibility during imaging, necessitates larger margins during radiotherapy planning and causes errors during radiation delivery. Computed tomography (CT) scans acquired synchronously with the respiratory signal can be used to reconstruct 4D CT scans, which can be employed for 4D treatment planning to explicitly account for respiratory motion. The aim of this research was to develop, test and clinically implement a method to acquire 4D thoracic CT scans using a multislice helical method. A commercial position-monitoring system used for respiratory-gated radiotherapy was interfaced with a third generation multislice scanner. 4D cardiac reconstruction methods were modified to allow 4D thoracic CT acquisition. The technique was tested on a phantom under different conditions: stationary, periodic motion and non-periodic motion. 4D CT was also implemented for a lung cancer patient with audio-visual breathing coaching. For all cases, 4D CT images were successfully acquired from eight discrete breathing phases, however, some limitations of the system in terms of respiration reproducibility and breathing period relative to scanner settings were evident. Lung mass for the 4D CT patient scan was reproducible to within 2.1% over the eight phases, though the lung volume changed by 20% between end inspiration and end expiration (870 cm3). 4D CT can be used for 4D radiotherapy, respiration-gated radiotherapy, 'slow' CT acquisition and tumour motion studies

  1. Progressive hearing loss following acquired cytomegalovirus infection in an immunocompromised child.

    Science.gov (United States)

    Kato, Ken; Otake, Hironao; Tagaya, Mitsuhiko; Takahashi, Yoshiyuki; Ito, Yoshinori; Hama, Asahito; Muramatsu, Hideki; Kojima, Seiji; Naganawa, Shinji; Nakashima, Tsutomu

    2013-01-01

    We report a rare case of progressive hearing loss after acquired CMV infection in a child with Langerhans cell histiocytosis (LCH). A 5-month-old female was diagnosed as having LCH. When she was 14 months old, she received an unrelated donor umbilical cord blood transfusion for the treatment of intractable LCH. CMV infection was confirmed after the blood transfusion. Because her own umbilical cord had no CMV, the CMV infection was not congenital. When she was 7 years old, mixed hearing loss was noted with bilateral otitis media with effusion. After that time, the sensorineural hearing loss progressed to bilateral profound hearing loss over 3 years. Three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging with gadolinium contrast enhancement revealed a high intensity area in the inner ear that suggested bilateral labyrinthitis. This case demonstrates the possibility that, under the immunodeficiency, the acquired CMV infection causes progressive sensorineural hearing loss.

  2. Meningitis and stridor in advanced Human immunodeficiency virus/acquired immune deficiency syndrome

    Directory of Open Access Journals (Sweden)

    Naidoo P

    2013-09-01

    Full Text Available P Naidoo, D Pillay, S SamanDepartment of Internal Medicine, Port Shepstone Regional Hospital, University of KwaZulu-Natal, South AfricaAbstract: A 37-year-old female presented confused with a preceding history of severe headache. After clinical examination and investigations, she was diagnosed with disseminated tuberculosis (including central nervous system involvement, and Human immunodeficiency virus/acquired immune deficiency syndrome. Her hospital stay was complicated. She developed stridor and a cerebrovascular accident with left hemiplegia. She died approximately 2 weeks after admission. The potential causes of her stridor included a mediastinal mass or a central mechanism secondary to tuberculosis meningitis. Limited resources precluded definitive imaging of the chest to rule out a mediastinal mass. Further, an autopsy was not done. Despite these limitations, this case is unique because it reports the presence of both stridor and tuberculosis meningitis in an adult patient.Keywords: Human immunodeficiency virus, acquired immune deficiency syndrome, meningitis, stridor, tuberculosis

  3. Dramatic regression of presumed acquired retinal astrocytoma with photodynamic therapy

    Directory of Open Access Journals (Sweden)

    Samuray Tuncer

    2014-01-01

    Full Text Available Photodynamic therapy (PDT has been used for treatment of various intraocular tumors including choroidal hemangioma, vasoproliferative tumor, amelanotic choroidal melanoma and choroidal neovascular membrane due to choroidal osteoma. This case report documents the effect of PDT for a presumed acquired retinal astrocytoma. A 42-year-old female with a juxtapapillary acquired astrocytoma was treated with a single session of PDT using standard parameters. The tumor showed dramatic regression over 6 months into a fibrotic scar. It remained regressed and stable with 20/20 vision after 51 months of follow-up. We believe that PDT can be used as a primary treatment for acquired retinal astrocytoma.

  4. Immunosuppression for acquired hemophilia A: results from the European Acquired Haemophilia Registry (EACH2).

    Science.gov (United States)

    Collins, Peter; Baudo, Francesco; Knoebl, Paul; Lévesque, Hervé; Nemes, László; Pellegrini, Fabio; Marco, Pascual; Tengborn, Lilian; Huth-Kühne, Angela

    2012-07-01

    Acquired hemophilia A (AHA) is an autoimmune disease caused by an autoantibody to factor VIII. Patients are at risk of severe and fatal hemorrhage until the inhibitor is eradicated, and guidelines recommend immunosuppression as soon as the diagnosis has been made. The optimal immunosuppressive regimen is unclear; therefore, data from 331 patients entered into the prospective EACH2 registry were analyzed. Steroids combined with cyclophosphamide resulted in more stable complete remission (70%), defined as inhibitor undetectable, factor VIII more than 70 IU/dL and immunosuppression stopped, than steroids alone (48%) or rituximab-based regimens (59%). Propensity score-matched analysis controlling for age, sex, factor VIII level, inhibitor titer, and underlying etiology confirmed that stable remission was more likely with steroids and cyclophosphamide than steroids alone (odds ratio = 3.25; 95% CI, 1.51-6.96; P < .003). The median time to complete remission was approximately 5 weeks for steroids with or without cyclophosphamide; rituximab-based regimens required approximately twice as long. Immunoglobulin administration did not improve outcome. Second-line therapy was successful in approximately 60% of cases that failed first-line therapy. Outcome was not affected by the choice of first-line therapy. The likelihood of achieving stable remission was not affected by underlying etiology but was influenced by the presenting inhibitor titer and FVIII level.

  5. Management of bleeding in acquired hemophilia A: results from the European Acquired Haemophilia (EACH2) Registry.

    Science.gov (United States)

    Baudo, Francesco; Collins, Peter; Huth-Kühne, Angela; Lévesque, Hervé; Marco, Pascual; Nemes, László; Pellegrini, Fabio; Tengborn, Lilian; Knoebl, Paul

    2012-07-01

    Acquired hemophilia A is a rare bleeding disorder caused by autoantibodies to coagulation FVIII. Bleeding episodes at presentation are spontaneous and severe in most cases. Optimal hemostatic therapy is controversial, and available data are from observational and retrospective studies only. The EACH2 registry, a multicenter, pan-European, Web-based database, reports current patient management. The aim was to assess the control of first bleeding episodes treated with a bypassing agent (rFVIIa or aPCC), FVIII, or DDAVP among 501 registered patients. Of 482 patients with one or more bleeding episodes, 144 (30%) received no treatment for bleeding; 31 were treated with symptomatic therapy only. Among 307 patients treated with a first-line hemostatic agent, 174 (56.7%) received rFVIIa, 63 (20.5%) aPCC, 56 (18.2%) FVIII, and 14 (4.6%) DDAVP. Bleeding was controlled in 269 of 338 (79.6%) patients treated with a first-line hemostatic agent or ancillary therapy alone. Propensity score matching was applied to allow unbiased comparison between treatment groups. Bleeding control was significantly higher in patients treated with bypassing agents versus FVIII/DDAVP (93.3% vs 68.3%; P = .003). Bleeding control was similar between rFVIIa and aPCC (93.0%; P = 1). Thrombotic events were reported in 3.6% of treated patients with a similar incidence between rFVIIa (2.9%) and aPCC (4.8%).

  6. CMOS Imaging Sensor Technology for Aerial Mapping Cameras

    Science.gov (United States)

    Neumann, Klaus; Welzenbach, Martin; Timm, Martin

    2016-06-01

    In June 2015 Leica Geosystems launched the first large format aerial mapping camera using CMOS sensor technology, the Leica DMC III. This paper describes the motivation to change from CCD sensor technology to CMOS for the development of this new aerial mapping camera. In 2002 the DMC first generation was developed by Z/I Imaging. It was the first large format digital frame sensor designed for mapping applications. In 2009 Z/I Imaging designed the DMC II which was the first digital aerial mapping camera using a single ultra large CCD sensor to avoid stitching of smaller CCDs. The DMC III is now the third generation of large format frame sensor developed by Z/I Imaging and Leica Geosystems for the DMC camera family. It is an evolution of the DMC II using the same system design with one large monolithic PAN sensor and four multi spectral camera heads for R,G, B and NIR. For the first time a 391 Megapixel large CMOS sensor had been used as PAN chromatic sensor, which is an industry record. Along with CMOS technology goes a range of technical benefits. The dynamic range of the CMOS sensor is approx. twice the range of a comparable CCD sensor and the signal to noise ratio is significantly better than with CCDs. Finally results from the first DMC III customer installations and test flights will be presented and compared with other CCD based aerial sensors.

  7. Imaging in pulsatile tinnitus

    Energy Technology Data Exchange (ETDEWEB)

    Madani, G. [Radiology Department, St Mary' s Hospital, London (United Kingdom)], E-mail: gittamadani@yahoo.com; Connor, S.E.J. [Neuroradiology Department, King' s College Hospital, London (United Kingdom)

    2009-03-15

    Tinnitus may be continuous or pulsatile. Vascular lesions are the most frequent radiologically demonstrable cause of pulsatile tinnitus. These include congenital vascular anomalies (which may be arterial or venous), vascular tumours, and a variety of acquired vasculopathies. The choice of imaging depends on the clinical findings. If a mass is present at otoscopy, thin-section computed tomography (CT) is indicated. In the otoscopically normal patient, there is a range of possible imaging approaches. However, combined CT angiography and venography is particularly useful.

  8. Acquired disorders of elastic tissue: Part II. decreased elastic tissue.

    Science.gov (United States)

    Lewis, Kevan G; Bercovitch, Lionel; Dill, Sara W; Robinson-Bostom, Leslie

    2004-08-01

    Elastic fibers in the extracellular matrix are integral components of dermal connective tissue. The resilience and elasticity required for normal structure and function of the skin are attributable to the network of elastic tissue. Advances in our understanding of elastic tissue physiology provide a foundation for studying the pathogenesis of elastic tissue disorders. Many acquired disorders are nevertheless poorly understood owing to the paucity of reported cases. Several acquired disorders in which loss of dermal elastic tissue produces prominent clinical and histopathologic features have recently been described, including middermal elastolysis, papular elastorrhexis, and pseudoxanthoma-like papillary dermal elastolysis, which must be differentiated from more well-known disorders such as anetoderma, acquired cutis laxa, and acrokeratoelastoidosis. Learning objective At the conclusion of this learning activity, participants should have an understanding of the similarities and differences between acquired disorders of elastic tissue that are characterized by a loss of elastic tissue.

  9. The Impact of Hospital-Acquired Conditions on Medicare..

    Data.gov (United States)

    U.S. Department of Health & Human Services — According to findings reported in The Impact of Hospital-Acquired Conditions on Medicare Program Payments, published in Volume 4, Issue 4 of the Medicare and...

  10. A methodology for acquiring qualitative knowledge for probabilistic graphical models

    DEFF Research Database (Denmark)

    Kjærulff, Uffe Bro; Madsen, Anders L.

    2004-01-01

    We present a practical and general methodology that simplifies the task of acquiring and formulating qualitative knowledge for constructing probabilistic graphical models (PGMs). The methodology efficiently captures and communicates expert knowledge, and has significantly eased the model...

  11. Examination of the Accuracy of Coding Hospital-Acquired...

    Data.gov (United States)

    U.S. Department of Health & Human Services — A new study, Examination of the Accuracy of Coding Hospital-Acquired Pressure Ulcer Stages, published in Volume 4, Issue 1 of the Medicare and Medicaid Research...

  12. Evaluation of Spectrodirectional Alfalfa Canopy Data Acquired During Daisex'99

    NARCIS (Netherlands)

    Strub, G.; Schaepman, M.E.; Knyazikhin, Y.; Itten, K.I.

    2003-01-01

    Field goniometer measurements are a tool to generate a priori bidirectional reflectance distribution function (BRDF) knowledge for correction and validation of directional reflectance data acquired by air- and spaceborne sensors. This study analyzes the diurnal hemispherical.-directional reflectance

  13. The Acquired Preparedness Model of Risk for Bulimic Symptom Development

    OpenAIRE

    Combs, Jessica L.; Smith, Gregory T.; Flory, Kate; Simmons, Jean R.; Hill, Kelly K.

    2010-01-01

    The authors applied person-environment transaction theory to test the acquired preparedness model of eating disorder risk. The model holds that (a) middle school girls high in the trait of ineffectiveness are differentially prepared to acquire high risk expectancies for reinforcement from dieting/thinness; (b) those expectancies predict subsequent binge eating and purging; and (c) the influence of the disposition of ineffectiveness on binge eating and purging is mediated by dieting/thinness e...

  14. Surgical management of stage 2 adult acquired flatfoot.

    Science.gov (United States)

    Maker, Jared M; Cottom, James M

    2014-07-01

    Adult acquired flatfoot deformity is a progressive disorder with multiple symptoms and degrees of deformity. Stage II adult acquired flatfoot can be divided into stage IIA and IIB based on severity of deformity. Surgical procedures should be chosen based on severity as well as location of the flatfoot deformity. Care must be taken not to overcorrect the flatfoot deformity so as to decrease the possibility of lateral column overload as well as stiffness.

  15. Acquired pure megakaryocytic aplasia successfully treated with cyclosporine

    Directory of Open Access Journals (Sweden)

    Halima El Omri

    2010-12-01

    Full Text Available Acquired pure megakaryocytic aplasia is a rare hematological disorder characterized by thrombocytopenia with absent or markedly reduced megakaryocytes in the bone marrow. We report a case of a 25-year-old male diagnosed as acquired pure megakaryocytic aplasia. Treatment with prednisone and intravenous immunoglobulin failed, but he was successfully treated with cyclosporine, with complete remission after 90 days and normal platelet count maintained thereafter.

  16. Acquired Dyslexia in Japanese: Implications for Reading Theory

    OpenAIRE

    Sato, H.

    2007-01-01

    Acquired dyslexia research has been conducted mainly on English neurological patients. A limited number of dyslexia studies on non-alphabetic orthographies are available. Classical case studies for acquired dyslexia in Japanese, which has two distinctive scripts (morphographic Kanji and phonographic Kana), reported 'script-dependent' dyslexia patterns. Although recent case studies showed 'script-independent' dyslexia patterns for surface and phonological dyslexia, a 'script-independent'...

  17. [Differential diagnosis of pulmonary tuberculosis and community-acquired pneumonia].

    Science.gov (United States)

    Deĭkina, O N; Mishin, V Iu; Demikhova, O V

    2007-01-01

    The purpose of this investigation was to enhance the efficiency of differential diagnosis of pneumonia and pulmonary tuberculosis. A hundred and fifty-nine adult patients were examined. These included 78 patients with pulmonary tuberculosis and 81 with community-acquired p neumonia. The clinical features of infiltrative pulmonary tuberculosis (n = 48) and mild community-acquired pneumonia (n = 51) were compared. The course of caseous pneumonia (n = 30) was compared with that of moderate and severe community-acquired pneumonia (n = 30). Significant differences in the manifestations of the intoxication and bronchopulmonary syndrome were not found in patients with community-acquired pneumonia and infiltrative pulmonary tuberculosis. Physical studies showed that in patients with community-acquired pneumonia, moist rale (54.9%) and crepitation (11.8%) were prevalent, but in those with infiltrative tuberculosis rale was absent in 60.4% of cases and the pattern of respiration was unchanged in 79.2%. Chest X-ray studies indicated that in patients with community-acquired pneumonia, lower lobar inflammatory changes were predominant in 62.8% of cases whereas in those with infiltrative pulmonary tuberculosis the process was mainly bilateral (43.8%) with the presence of destructive changes (83.3%) and bronchogenic dissemination (66.7%). In patients with caseous pneumonia, the intoxication syndrome was more significant than in those with severe community-acquired pneumonia. Chest X-ray studies demonstrated that in patients with caseous pneumonia, specific changes were bilateral with the involvement of 2 lobes or more, with destruction and bronchogenic dissemination while in those with community-acquired pneumonia, the pulmonary processes were predominantly bilateral (76.6%) at the lower lobar site (36.7%).

  18. [Differential diagnosis of pulmonary tuberculosis and community-acquired pneumonia].

    Science.gov (United States)

    Deĭkina, O N; Mishin, V Iu; Demikhova, O V

    2007-01-01

    The purpose of this investigation was to enhance the efficiency of differential diagnosis of pneumonia and pulmonary tuberculosis. A hundred and fifty-nine adult patients were examined. These included 78 patients with pulmonary tuberculosis and 81 with community-acquired p neumonia. The clinical features of infiltrative pulmonary tuberculosis (n = 48) and mild community-acquired pneumonia (n = 51) were compared. The course of caseous pneumonia (n = 30) was compared with that of moderate and severe community-acquired pneumonia (n = 30). Significant differences in the manifestations of the intoxication and bronchopulmonary syndrome were not found in patients with community-acquired pneumonia and infiltrative pulmonary tuberculosis. Physical studies showed that in patients with community-acquired pneumonia, moist rale (54.9%) and crepitation (11.8%) were prevalent, but in those with infiltrative tuberculosis rale was absent in 60.4% of cases and the pattern of respiration was unchanged in 79.2%. Chest X-ray studies indicated that in patients with community-acquired pneumonia, lower lobar inflammatory changes were predominant in 62.8% of cases whereas in those with infiltrative pulmonary tuberculosis the process was mainly bilateral (43.8%) with the presence of destructive changes (83.3%) and bronchogenic dissemination (66.7%). In patients with caseous pneumonia, the intoxication syndrome was more significant than in those with severe community-acquired pneumonia. Chest X-ray studies demonstrated that in patients with caseous pneumonia, specific changes were bilateral with the involvement of 2 lobes or more, with destruction and bronchogenic dissemination while in those with community-acquired pneumonia, the pulmonary processes were predominantly bilateral (76.6%) at the lower lobar site (36.7%). PMID:17338353

  19. Adult-Onset Acquired Partial Lipodystrophy Accompanied by Rheumatoid Arthritis

    Directory of Open Access Journals (Sweden)

    Yusuke Muto

    2015-04-01

    Full Text Available Lipodystrophy is a group of metabolic disorders, possibly caused by autoimmune disease. In this report, we describe a case of adult-onset acquired partial lipodystrophy accompanied by rheumatoid arthritis without a family history. Interestingly, immunohistochemical staining revealed dense infiltration of IL-27-producing cells as well as MMP-7- and MMP-28-expressing cells, both of which have been reported to facilitate the development of autoimmune disease. Our present case might suggest possible mechanisms for acquired partial lipodystrophy.

  20. Acquiring 3-D Spatial Data Of A Real Object

    Science.gov (United States)

    Wu, C. K.; Wang, D. Q.; Bajcsy, R. K...

    1983-10-01

    A method of acquiring spatial data of a real object via a stereometric system is presented. Three-dimensional (3-D) data of an object are acquired by: (1) camera calibration; (2) stereo matching; (3) multiple stereo views covering the whole object; (4) geometrical computations to determine the 3-D coordinates for each sample point of the object. The analysis and the experimental results indicate the method implemented is capable of measuring the spatial data of a real object with satisfactory accuracy.

  1. LANDSLIDE MAPPING USING IMAGERY ACQUIRED BY A FIXED-WING UAV

    Directory of Open Access Journals (Sweden)

    J. Y. Rau

    2012-09-01

    Full Text Available In Taiwan, the average annual rainfall is about 2,500 mm, about three times the world average. Hill slopes where are mostly under meta-stable conditions due to fragmented surface materials can easily be disturbed by heavy typhoon rainfall and/or earthquakes, resulting in landslides and debris flows. Thus, an efficient data acquisition and disaster surveying method is critical for decision making. Comparing with satellite and airplane, the unmanned aerial vehicle (UAV is a portable and dynamic platform for data acquisition. In particularly when a small target area is required. In this study, a fixed-wing UAV that equipped with a consumer grade digital camera, i.e. Canon EOS 450D, a flight control computer, a Garmin GPS receiver and an attitude heading reference system (AHRS are proposed. The adopted UAV has about two hours flight duration time with a flight control range of 20 km and has a payload of 3 kg, which is suitable for a medium scale mapping and surveying mission. In the paper, a test area with 21.3 km2 in size containing hundreds of landslides induced by Typhoon Morakot is used for landslides mapping. The flight height is around 1,400 meters and the ground sampling distance of the acquired imagery is about 17 cm. The aerial triangulation, ortho-image generation and mosaicking are applied to the acquired images in advance. An automatic landslides detection algorithm is proposed based on the object-based image analysis (OBIA technique. The color ortho-image and a digital elevation model (DEM are used. The ortho-images before and after typhoon are utilized to estimate new landslide regions. Experimental results show that the developed algorithm can achieve a producer's accuracy up to 91%, user's accuracy 84%, and a Kappa index of 0.87. It demonstrates the feasibility of the landslide detection algorithm and the applicability of a fixed-wing UAV for landslide mapping.

  2. Rotationally acquired four-dimensional optical coherence tomography of embryonic chick hearts using retrospective gating on the common central A-scan

    DEFF Research Database (Denmark)

    Happel, Christoph M.; Thommes, Jan; Thrane, Lars;

    2011-01-01

    We introduce a new method of rotational image acquisition for four-dimensional (4D) optical coherence tomography (OCT) of beating embryonic chick hearts. The rotational axis and the central A-scan of the OCT are identical. An out-of-phase image sequence covering multiple heartbeats is acquired at.......We demonstrate this approach and provide a video of a beating Hamburger and Hamilton stage 16 embryonic chick heart generated from a 4D OCT data set using rotational image acquisition....

  3. Residual fMRI sensitivity for identity changes in acquired prosopagnosia

    Directory of Open Access Journals (Sweden)

    Christopher J Fox

    2013-10-01

    Full Text Available While a network of cortical regions contribute to face processing, the lesions in acquired prosopagnosia are highly variable, and likely result in different combinations of spared and affected regions of this network. To assess the residual functional sensitivities of spared regions in prosopagnosia, we designed a rapid event-related functional magnetic resonance imaging (fMRI experiment that included pairs of faces with same or different identities and same or different expressions. By measuring the release from adaptation to these facial changes we determined the residual sensitivity of face-selective regions-of-interest. We tested three patients with acquired prosopagnosia, and all three of these patients demonstrated residual sensitivity for facial identity changes in surviving fusiform and occipital face areas of either the right or left hemisphere, but not in the right posterior superior temporal sulcus. The patients also showed some residual capabilities for facial discrimination with normal performance on the Benton Facial Recognition Test, but impaired performance on more complex tasks of facial discrimination. We conclude that fMRI can demonstrate residual processing of facial identity in acquired prosopagnosia, that this adaptation can occur in the same structures that show similar processing in healthy subjects, and further, that this adaptation may be related to behavioral indices of face perception.

  4. Chest radiographic characteristics of community-acquired Legionella pneumonia in the elderly

    Institute of Scientific and Technical Information of China (English)

    Zhang Zhigang; Liu Xinmin; Chen Luzeng; Qiu Jianxing

    2014-01-01

    Background Legionella is an important community-acquired pneumonia pathogen.Although the elderly are especially susceptible to Legionella,few studies have looked at comparative radiographic features of Legionella pneumonia in this population.The aim of this study was to explore the chest radiographic characteristics of community-acquired Legionella pneumonia in the elderly.Methods Serial chest radiographs obtained in 34 patients hospitalized with serologically proven Legionella pneumonia were retrospectively reviewed.Chest x-ray features of an aged group of ≥65 years were assessed and compared with a non-aged group of <65 years old with regard to initial patterns and distributions of pulmonary abnormalities,accompanying signs,and progression.Results The most common initial presentation was a patchy alveolar infiltrate involving a single lobe,most often the lower lobe.There was no middle or lingular lobe involvement in the aged group patients,but bilateral pleural effusion was significantly more common in this group.In the aged group patients,radiographic progression following adequate therapy,despite a clinical response,was more often noted and the radiographs were less likely to have returned to the premorbid state at discharge,but the differences were not significant between the two groups.Conclusion The discrepancy between imaging findings and clinical symptoms seems more prominent in community-acquired Legionella pneumonia in the elderly.

  5. Connectionist neuropsychology: uncovering ultimate causes of acquired dyslexia.

    Science.gov (United States)

    Woollams, Anna M

    2014-01-01

    Acquired dyslexia offers a unique window on to the nature of the cognitive and neural architecture supporting skilled reading. This paper provides an integrative overview of recent empirical and computational work on acquired dyslexia within the context of the primary systems framework as implemented in connectionist neuropsychological models. This view proposes that damage to general visual, phonological or semantic processing abilities are the root causes of different forms of acquired dyslexia. Recent case-series behavioural evidence concerning pure alexia, phonological dyslexia and surface dyslexia that supports this perspective is presented. Lesion simulations of these findings within connectionist models of reading demonstrate the viability of this approach. The commitment of such models to learnt representations allows them to capture key aspects of performance in each type of acquired dyslexia, particularly the associated non-reading deficits, the role of relearning and the influence of individual differences in the premorbid state of the reading system. Identification of these factors not only advances our understanding of acquired dyslexia and the mechanisms of normal reading but they are also relevant to the complex interactions underpinning developmental reading disorders.

  6. Mucocutaneous manifestations of acquired hypoparathyroidism: An observational study

    Directory of Open Access Journals (Sweden)

    Somenath Sarkar

    2012-01-01

    Full Text Available Hypoparathyroidism is a disorder of calcium and phosphorus metabolism due to decreased secretion of parathyroid hormone. Hypoparathyroidism can be hereditary and acquired. Acquired hypoparathyroidism usually occurs following neck surgery (thyroid surgery or parathyroid surgery. Along with systemic manifestations, hypoparathyroidism produces some skin manifestations. Lack of study regarding mucocutaneous manifestations of acquired hypoparathyroidism prompted us to undertake this study. To evaluate the mucocutaneous manifestations of acquired hypoparathyroidism. An observational study done in a tertiary care hospital of Kolkata by comprehensive history taking, through clinical examination and relevant laboratory investigations. Twenty-one patients were included in the study. The commonest form of acquired hypoparathyroidism was neck surgery (thyroidectomy and parathyroidectomy operation. Mucocutaneous manifestations were present in 76.19% of patients. The most frequent mucocutaneous manifestation was found in the hairs like the loss of axillary hair (61.9%, loss of pubic hair (52.38%, coarsening of body hair (47.62%, and alopecia areata (9.52%. The nail changes noted were brittle and ridged nail, followed by onycholysis, onychosezia, and onychomedesis. The most common skin features were xerotic skin in 11 patients (52.38%, followed by pellagra-like skin pigmentation, pustular psoriasis and acne form eruption, bullous impetigo, etc. Mucosa was normal in all the cases excepting the one which showed oral candidiasis.

  7. Optimization of Synthetic Aperture Image Quality

    OpenAIRE

    Moshavegh, Ramin; Jensen, Jonas; Villagómez Hoyos, Carlos Armando; Stuart, Matthias Bo; Hemmsen, Martin Christian; Jensen, Jørgen Arendt

    2016-01-01

    Synthetic Aperture (SA) imaging produces high-quality images and velocity estimates of both slow and fast flow at high frame rates. However, grating lobe artifacts can appear both in transmission and reception. These affect the image quality and the frame rate. Therefore optimization of parameters effecting the image quality of SA is of great importance, and this paper proposes an advanced procedure for optimizing the parameters essential for acquiring an optimal image quality, while generati...

  8. Computed tomography in the evaluation of acquired stenosis in the neonate

    Energy Technology Data Exchange (ETDEWEB)

    Faw, K.; Muntz, H.; Siegel, M.; Spector, G.

    1982-01-01

    We studied the feasibility of computed tomographic evaluation of the neonatal airway. Three neonatal larynges, removed at necroscopy, were examined by computed tomography. Good resolution of soft tissue, cartilage and airway lumen was obtained in these small specimens. On the basis of these findings two neonates with acquired subglottic stenosis were examined by endoscopy, soft tissue airway radiographs, and computed tomography. Measurements of radiation dose revealed that a computed tomographic study delivered 36% of the mean tissue dose of standard image intensifier fluoroscopy. Computed tomography and fluoroscopy both demonstrated the degree and length of this stenosis accurately. An advantage of CT over conventional imaging procedures was better definition of the cross sectional area of the airway.

  9. Hospital-acquired infections - when are hospitals legally liable?

    Science.gov (United States)

    McQuoid-Mason, David

    2012-04-12

    Hospital-acquired infections (nosocomial infections) are acquired in healthcare settings by patients admitted for reasons unrelated to the infection or not previously infected when admitted to the facility. Liability for hospital-acquired infections depends on whether the hospital: (i) has introduced best practice infection control measures; (ii) has implemented best practice infection control measures; or (iii) will be vicariously liable for negligent or intentional failures by staff to comply with the infection control measures implemented. A hospital and hospital administrators may be held directly liable for not introducing or implementing best practice infection control measures, resulting in harm to patients. The hospital may also be held vicariously liable where patients have been harmed because hospital staff negligently or intentionally failed to comply with the infection control measures that have been implemented by the hospital, during the course and scope of their employment.

  10. Detecting mechanisms of acquired BRAF inhibitor resistance in melanoma.

    Science.gov (United States)

    Lo, Roger S; Shi, Hubing

    2014-01-01

    (V600)BRAF mutation was identified as an ideal target for clinical therapy due to its indispensable roles in supporting melanoma initiation and progression. Despite the fact that BRAF inhibitors (BRAFi) can elicit anti-tumor responses in the majority of treated patients and confer overall survival benefits, acquired drug resistance is a formidable obstacle to long-term management of the disease. Several aberrant events including RTK upregulation, NRAS mutation, mutant BRAF amplification or alternative splicing, and MEK mutation have been reported as acquired BRAFi resistance mechanisms. Clinially, detection of these resistance mechanisms help understand drug response patterns and help guide combinatorial therapeutic strategies. Therefore, quick and accurate diagnosis of the resistant mechanisms in tumor biopsies has become an important starting point for personalized therapy. In this chapter, we review the major acquired BRAFi resistance mechanisms, highlight their therapeutic implications, and provide the diagnostic methods from clinical samples.

  11. REVIEW OF A CASE OF CHILD WITH ACQUIRED APHASIA

    Directory of Open Access Journals (Sweden)

    Silvana FILIPOVA

    2004-12-01

    Full Text Available Achieved children speech disabilities are manifested at certain level of development of speech from the age of 3 to 12 years. The speech disabilities with children from the age of one to three years have developmental and acquired characteristics. It is well-known when and why the disabilities occurr at acquired aphasia or disphasia.The child with acquired aphasia or disphasia has early brain impairements and a relative improvement happens with adequate treatment and prompt rehabilitation treatment. It is more obvious with children than with adults.This fast and complete rehabilitation happens due to the plastic character of child’s brain and the possibilities for intro-hemisphere and inter-hemisphere reorganization of speech functions in childhood.

  12. Free Auricular Composite Graft for Acquired Nasal Stenosis

    Science.gov (United States)

    Riley, Charles A.; Lawlor, Claire M.; Gray, Mingyang Liu; Graham, H. Devon

    2016-01-01

    Background: Acquired nasal stenosis poses a reconstructive challenge for the facial plastic surgeon. Many surgical options are available, ranging from primary closure to skin grafts to free flap reconstruction for complex defects. The free auricular composite graft is a single-stage procedure that can be used to repair nasal vestibular stenosis causing nasal obstruction. Case Report: We present the case of a patient with acquired nasal stenosis as a result of prolonged nasal tampon placement secondary to severe epistaxis and subsequent nasal vestibular infection. Repair via auricular composite graft was successful, and we provide a thorough explanation of graft design and operative technique. Conclusion: Free auricular composite grafts can produce desirable functional and aesthetic outcomes and should be considered in patients presenting with acquired nasal stenosis. PMID:27303225

  13. Tuberculosis and the acquired immune deficiency syndrome in South Brazil

    International Nuclear Information System (INIS)

    Tuberculosis and the acquired immune deficiency syndrome in South Brazil. The authors studied the incidence of tuberculosis in South Brazilian patients with acquired immune deficiency syndrome from January 1985 to June 1988. During this period, tuberculosis occurred in 10.3% of acquired immune deficiency syndrome patients. The socioeconomic conditions and the incidence of disease in the population were not confirmed as a potential risk for tuberculosis infection. Chest radiographs revealed pulmonary infiltrates in six patients, hilar and/or mediastinal adenopathy in three, and pleural effusion in two. The two remaining patients had pulmonary consolidation associated with other features. None of these patients presented pulmonary cavitation or radiographic findings of typical reactivation of pulmonary tuberculosis. (author)

  14. Narratives of athletic identity after acquiring a permanent physical disability.

    Science.gov (United States)

    Perrier, Marie-José; Smith, Brett; Strachan, Shaelyn M; Latimer, Amy E

    2014-04-01

    Individuals with acquired physical disabilities report lower levels of athletic identity. The objective of this study was to further explore why athletic identity may be lost or (re)developed after acquiring a physical disability. Seven women and four men (range = 28-60 years) participated in approximately 1-hour-long semistructured interviews; data were subjected to a narrative analysis. The structural analysis revealed three narrative types. The nonathlete narrative described physical changes in the body as reasons for diminished athletic identity. The athlete as a future self primarily focused on present sport behavior and performance goals such that behavior changes diminished athletic identity. The present self as athlete narrative type focused on the aspects of their present sport involvement, such as feedback from other athletes and skill development, which supported their athletic identity. Implications of these narrative types with respect to sport promotion among people with acquired physical disabilities are discussed.

  15. Cerebral imaging and dementia

    Energy Technology Data Exchange (ETDEWEB)

    Rascol, A.; Celsis, P.; Berry, I.

    1989-02-01

    Modern imaging techniques undoubtedly are of value when applied to the study of dementia. This value, however, varies with the technique utilized, and one must distinguish between acquired and potential knowledge. Morphological imaging with computerized tomography or magnetic resonance detects or confirms certain causes of dementia (tumours, lacunae, hydrocephalus with normal CSF pressure), but it is still not sensitive and specific enough to be very useful in primary dementias. Functional imaging (essentially with emission tomography) has already provided interesting data in the study of degenerative dementia (correlations with neuropsychology, subtyping), but what is most promising is its possibilities in the physiopathological approach of the disease.

  16. Mars Image Collection Mosaic Builder

    Science.gov (United States)

    Plesea, Lucian; Hare, Trent

    2008-01-01

    A computer program assembles images from the Mars Global Surveyor (MGS) Mars Observer Camera Narrow Angle (MOCNA) collection to generate a uniform-high-resolution, georeferenced, uncontrolled mosaic image of the Martian surface. At the time of reporting the information for this article, the mosaic covered 7 percent of the Martian surface and contained data from more than 50,000 source images acquired under various light conditions at various resolutions.

  17. Reconstruction of Undersampled Atomic Force Microscopy Images

    DEFF Research Database (Denmark)

    Jensen, Tobias Lindstrøm; Arildsen, Thomas; Østergaard, Jan;

    2013-01-01

    Atomic force microscopy (AFM) is one of the most advanced tools for high-resolution imaging and manipulation of nanoscale matter. Unfortunately, standard AFM imaging requires a timescale on the order of seconds to minutes to acquire an image which makes it complicated to observe dynamic processes...

  18. UNSUPERVISED WOUND IMAGE SEGMENTATION

    Directory of Open Access Journals (Sweden)

    K. Sundeep Kumar

    2014-02-01

    Full Text Available The purpose of our research is to introduce two unique approaches for the unsupervised segmentation of wound images. The first method of segmentation is by using the texture of the image and is performed using the multi-channel filtering hypothesis for the processing of visual or optical data during the preliminary stages of the Human Visual System. We obtain the different channels from an image by filtering the image using a Gabor Filter Bank. The textural features are obtained from each filtered image and the final segmented image is acquired by reconstructing the original input image from these filtered images. The second method of segmentation was performed using parametric kernel graph cuts. Using a kernel function we transform the image data implicitly such that a piecewise constant model of the graph cut interpretation is now applicable. The objective function comprises of an original data term in order to assess the deviance of the transformed data from the initial input data within each partition. This method avoids sophisticated modelling of the input image data while availing of the computational advantages of graph cuts. By using a conventional kernel function, the energy minimization boils down to image partitioning via graph cut iterations and assessments of region parameters by means of fixed point calculations. The efficacy and flexibility of both the methods are established by carrying out investigations on real wound images.

  19. Microsoft Acquired Nokia in Unipolar Operating System Market

    OpenAIRE

    Netra Pal Singh

    2014-01-01

    The recent big tickets include Microsoft acquiring part of Nokia for US$ 7.2 billion, Verizon buy 45% stake in Vodafone for US$130 billion, Google acquiring Motorola for 12.5 billion. These buyouts are analyzed and commented by experts of the industry. This research paper attempted to collate their view in the context of Microsoft and Nokia deal on six parameters. These parameters are (i) reasons for the downfall of the Nokia market share, (ii) general comments of the experts, (iii) similarit...

  20. ACQUIRE: A data acquisition system for CAMAC on SUN workstation

    International Nuclear Information System (INIS)

    The data acquisition software package ACQUIRE been used for many years by the Princeton University Cyclotron Laboratory for nuclear physics research applications. This code has been ported to the SUN Sparc workstation and is fully functional, including block data transfers using an in crate Event Handler. A SCSI interface to CAMAC is utilized, and the device handling software has been developed in such a way that little modification was needed in the ACQUIRE code for the SUN implementation. The Higz X windows graphics package from CERN is used for data display

  1. [Features of morbidity community-acquired pneumonia among young recruits].

    Science.gov (United States)

    Serdukov, D U; Gordienko, A V; Kozlov, M S; Mikhailov, A A; Davydov, P A

    2015-10-01

    Were examined 3338 military personnel of the combined training center. 183 of them diagnosed community-acquired pneumonia, in 3155 focal and infiltrative changes in lung tissue were not identified. The analisys of prevalence been made among young recruits of the acute respiratory illness before arriving in part and at the assembly point, foci of chronic infection, smoking, low body weight. 511 military personnel arrived at the training center in the disease state with symptoms of acute respiratory illness. Examined the relationship these risk factor to the development of community-acquired pneumonia in this category of servicemen. PMID:26827502

  2. Recurrent stroke as a presenting feature of acquired partial lipodystrophy

    Directory of Open Access Journals (Sweden)

    Namburi R Prasad

    2012-01-01

    Full Text Available Acquired partial lipodystrophy (PL (Barraquer-Simons syndrome is a rare condition with onset in childhood, and it is characterized by progressive loss of subcutaneous fat in a cephalocaudal fashion. This report describes a case of acquired PL in a 16-year-old girl, who had progressive loss of facial fat since 3 years. Systemic lupus erythematosus (SLE, anticardiolipin antibody, primary hypothyroidism, diabetes, and dyslipidemia may antedate the development of complications such as cerebrovascular stroke and cardiovascular disease. The girl had developed recurrent left hemiparesis, and withdrawn from school due to poor performance.

  3. Mycosis fungoides: an important differential diagnosis for acquired palmoplantar keratoderma.

    Science.gov (United States)

    Kim, Janet; Foster, Rachael; Lam, Minh; Kumarasinghe, Sujith Prasad

    2015-02-01

    Mycosis fungoides is the most common subtype of primary cutaneous lymphoma and has several clinical variants. We report a 74-year-old man presenting with an acquired palmoplantar keratoderma initially diagnosed and treated as psoriasis with suboptimal improvement. Several months later the patient developed patches and plaques that were histologically consistent with mycosis fungoides. These lesions were ameliorated with the treatment of the underlying mycosis fungoides and the palmoplantar keratoderma resolved promptly with radiotherapy. This case highlights the importance of considering mycosis fungoides as an infrequent but serious cause of acquired palmoplantar keratoderma.

  4. [Two Cases of Rapidly Progressive Community-acquired Pneumonia Due to Pseudomonas aeruginosa].

    Science.gov (United States)

    Takakura, Akira; Katono, Ken; Harada, Shinya; Igawa, Satoshi; Katagiri, Masato; Yanase, Nobuo; Masuda, Noriyuki

    2015-01-01

    Pseudomonas aeruginosa is a significant causative bacterium in hospital-acquired pneumonia and nursing and healthcare-associated pneumonia, but it seems to be rare in community-acquired pneumonia (CAP). We report two cases of severe CAP due to P. aeruginosa. Case 1: A 52-year-old man was referred to our hospital for chest and back pain. He was being treated for diabetes mellitus and had a long history of smoking. Chest images showed consolidation in the right upper lobe. Soon after hospitalization, he developed sepsis shock and died seven hours later. Case 2: A 73-year-old man with a history of heavy smoking was referred to our hospital for right chest pain. Chest images showed right upper lobe pneumonia. Although wide-spectrum antimicrobial agents were administrated, he died ten hours after admission. In both cases, there was a rapid progression to death, despite administration of a broad spectrum of antibiotics and treatment for sepsis. In cases of CAP involving the right upper lobe, the possibility of bacteremia and rapid progress should be considered. PMID:26548298

  5. Measurement error analysis of three dimensional coordinates of tomatoes acquired using the binocular stereo vision

    Science.gov (United States)

    Xiang, Rong

    2014-09-01

    This study analyzes the measurement errors of three dimensional coordinates of binocular stereo vision for tomatoes based on three stereo matching methods, centroid-based matching, area-based matching, and combination matching to improve the localization accuracy of the binocular stereo vision system of tomato harvesting robots. Centroid-based matching was realized through the matching of the feature points of centroids of tomato regions. Area-based matching was realized based on the gray similarity between two neighborhoods of two pixels to be matched in stereo images. Combination matching was realized using the rough disparity acquired through centroid-based matching as the center of the dynamic disparity range which was used in area-based matching. After stereo matching, three dimensional coordinates of tomatoes were acquired using the triangle range finding principle. Test results based on 225 stereo images captured at the distances from 300 to 1000 mm of 3 tomatoes showed that the measurement errors of x coordinates were small, and can meet the need of harvesting robots. However, the measurement biases of y coordinates and depth values were large, and the measurement variation of depth values was also large. Therefore, the measurement biases of y coordinates and depth values, and the measurement variation of depth values should be corrected in the future researches.

  6. On line portal imaging

    International Nuclear Information System (INIS)

    is finding a common frame of reference for the simulator and portal images, since the location of the radiation field within the pixel matrix may differ for the two images. This problem is compounded by the fact that the commercially available EPIDs have mechanical slop and do not deploy to exactly the same position repeatedly. As a result, a common frame of reference has to be established before the anatomic structures in the images can be registered - generally by registering radiation field edges identified in the simulator and portal images. In addition, distortions in patient geometry or rotations out of the image plane can confound the image registration techniques. Despite the difficulties, many image registration techniques such as interactive techniques, landmark-based techniques, contrast-based techniques, and hybrid techniques have been developed to detect errors in patient positioning. The advantages and disadvantages of these various techniques will be discussed. Clinical use of portal imaging systems has included the use of static localisation and verification images, the use of 'movie' sequences (sequences of images acquired during one irradiation) and the use of 'time-lapse' sequences of images acquired during consecutive treatments, which demonstrate the variability in patient set-up over a full course of therapy. Possibly the most contentious issue is how to best make use of the information provided the portal images. Philosophies have ranged between intervening in every treatment, to intervening only occasionally, or to identifying patients who would benefit from smaller treatment margins and modifying the treatment plan part way through the course of treatment. Conclusions: While great improvements in portal imaging technology have been made, in the future more effort will to be directed towards improving image quality, and integrating and automating the various steps in the image registration process. In addition, other uses for portal imaging

  7. X-ray imaging using digital cameras

    Science.gov (United States)

    Winch, Nicola M.; Edgar, Andrew

    2012-03-01

    The possibility of using the combination of a computed radiography (storage phosphor) cassette and a semiprofessional grade digital camera for medical or dental radiography is investigated. We compare the performance of (i) a Canon 5D Mk II single lens reflex camera with f1.4 lens and full-frame CMOS array sensor and (ii) a cooled CCD-based camera with a 1/3 frame sensor and the same lens system. Both systems are tested with 240 x 180 mm cassettes which are based on either powdered europium-doped barium fluoride bromide or needle structure europium-doped cesium bromide. The modulation transfer function for both systems has been determined and falls to a value of 0.2 at around 2 lp/mm, and is limited by light scattering of the emitted light from the storage phosphor rather than the optics or sensor pixelation. The modulation transfer function for the CsBr:Eu2+ plate is bimodal, with a high frequency wing which is attributed to the light-guiding behaviour of the needle structure. The detective quantum efficiency has been determined using a radioisotope source and is comparatively low at 0.017 for the CMOS camera and 0.006 for the CCD camera, attributed to the poor light harvesting by the lens. The primary advantages of the method are portability, robustness, digital imaging and low cost; the limitations are the low detective quantum efficiency and hence signal-to-noise ratio for medical doses, and restricted range of plate sizes. Representative images taken with medical doses are shown and illustrate the potential use for portable basic radiography.

  8. Grief and Needs of Adults with Acquired Visual Impairments

    Science.gov (United States)

    Murray, Shirley A.; McKay, Robert C.; Nieuwoudt, Johan M.

    2010-01-01

    This report aims to illuminate the complex phenomenon of grief and the needs experienced throughout the time course of their impairments by adults with acquired visual impairments. The study applied a phenomenological research strategy using 10 case studies of South African adults, visually impaired within and beyond six years. Qualitative…

  9. On the difficulties of acquiring mathematical experience: Case rural education

    DEFF Research Database (Denmark)

    Booss-Bavnbek, Bernhelm

    2014-01-01

    Based on a variety of philosophical approaches and my own work for decades in pure and applied mathematics teaching and research, I explain my view upon the basic difficulties of acquiring the “Mathematical Experience” (in the sense of P.J. Davis and R. Hersh 1981) and submit a list of claims how...

  10. Unexpected postpartum hemorrhage due to an acquired factor VIII inhibitor.

    Science.gov (United States)

    Paidas, Michael J; Hossain, Nazli

    2014-09-01

    Unexplained postpartum hemorrhage (PPH) refractory to standard hemostatic measures should trigger a heightened clinical suspicion of an acquired bleeding disorder. When hemostatic medical interventions and surgical procedures fail to control the bleeding, then significant postoperative blood loss, debilitating morbidity, loss of fertility, and death may occur. In the setting of an autoantibody inhibitor to factor VIII (FVIII), control of life-threatening PPH and avoidance of subsequent bleeding episodes depends on a timely and accurate diagnosis, prompt hemostatic treatment and eradication of FVIII inhibitors, and appropriate long-term patient care and management. Acquired postpartum hemophilia due to a FVIII inhibitor is a rare cause of PPH; however, delayed treatment can lead to increased maternal morbidity and mortality. Acquired FVIII inhibitors also pose an emerging bleeding threat to the neonate as a result of possible transplacental transfer of FVIII autoantibodies to the fetus during the last trimester of pregnancy. The purpose of this review is to increase awareness among hematologists and obstetricians/gynecologists regarding the occurrence of FVIII neutralizing autoantibodies as a cause of PPH, and emphasize the importance of collaboration between obstetrician/gynecologists and hematology specialists to optimize the diagnostic evaluation, treatment, and long-term management of women who experience PPH due to an acquired FVIII inhibitor. PMID:24338123

  11. Surgical decision making for stage IV adult acquired flatfoot disorder.

    Science.gov (United States)

    Peterson, Kyle S; Hyer, Christopher F

    2014-07-01

    Adult acquired flatfoot deformity is a debilitating musculoskeletal condition affecting the lower extremity. Posterior tibial tendon dysfunction (PTTD) is the primary etiology for the development of a flatfoot deformity in an adult. PTTD is classified into 4 stages (with stage IV subdivided into stage IV-A and IV-B). This classification is described in detail in this article.

  12. A Corpus-Based Comparative Study of "Learn" and "Acquire"

    Science.gov (United States)

    Yang, Bei

    2016-01-01

    As an important yet intricate linguistic feature in English language, synonymy poses a great challenge for second language learners. Using the 100 million-word British National Corpus (BNC) as data and the software Sketch Engine (SkE) as an analyzing tool, this article compares the usage of "learn" and "acquire" used in natural…

  13. Atypical pathogens in community acquired pneumonia of Egyptian children

    Institute of Scientific and Technical Information of China (English)

    Deraz TE; El Sahriggy SA; Shaheen MA; Motawea AA; Gomaa HE; Fawzy SH; Mohamed AA

    2009-01-01

    Objective:Diagnosis of atypical pathogens as an aetiology for community-acquired pneumonia (CAP)in chil-dren is a challenge world wide.The aim of this study was to detect the frequency of atypical pathogens as a cause of community-acquired pneumonia (CAP)in Egyptian children.Methods:From 50 children (with age ranged from 2 months to 1 2 years)hospitalized for community-acquired pneumonia;respiratory sputum samples were collected by induction or spontaneously.All samples were subjected to conventional cultures and Polymer-ase Chain Reaction(PCR)technique DNA extraction for identification of Mycoplasma,Chlamydia pneumoniae and Legionella pneumophila.Results:A definite pathogen was identified in 78% of the studied children;30%typical bacteria,8% candida albicans and atypical bacteria in 40% of the pneumonic children.Chlamydia pneumoniae was isolated from 26% of the children while Mycoplasma pneumoniae was isolated from 1 4%, whereas Legionella pneumophilla was not isolated at all.Conclusion:Atypical pathogens are evident as a po-tential aetiology for community-acquired pneumonia in (1 3.3%)of young and (80%)of older Egyptian chil-dren.

  14. Antibiotic Treatment Strategies for Community-Acquired Pneumonia in Adults

    NARCIS (Netherlands)

    Postma, Douwe F.; Van Werkhoven, Cornelis H.; Van Elden, Leontine J R; Thijsen, Steven F T; Hoepelman, Andy I M; Kluytmans, Jan A J W; Boersma, Wim G.; Compaijen, Clara J.; Van Der Wall, Eva; Prins, Jan M.; Oosterheert, Jan J.; Bonten, Marc J M

    2015-01-01

    BACKGROUND The choice of empirical antibiotic treatment for patients with clinically suspected community-acquired pneumonia (CAP) who are admitted to non-intensive care unit (ICU) hospital wards is complicated by the limited availability of evidence. We compared strategies of empirical treatment (al

  15. Learning through Business Games: Acquiring Competences within Virtual Realities

    Science.gov (United States)

    Fortmuller, Richard

    2009-01-01

    The didactic function of business games is often seen only in the development of sociocommunicative competences and general problem-solving strategies. An equally important aspect of business games lies in the acquirement of technical and problem-oriented knowledge, which is the focus of this article. Moreover, this knowledge dimension is further…

  16. Acquired TTP: ADAMTS13 meets the immune system

    NARCIS (Netherlands)

    N. Sorvillo

    2013-01-01

    Autoantibodies directed against ADAMTS13 prohibit the processing of VWF multimers, initiating a rare and life-threatening disorder called acquired thrombotic thrombocytopenic purpura (TTP). At present it is not clear why previously healthy individuals develop anti-ADAMTS13 antibodies. The studies de

  17. [Acquired agammaglobulinaemia with predominantly intestinal symptoms (author's transl)].

    Science.gov (United States)

    Goldach, R; Wittwer, J

    1977-11-01

    In a 45-year-old female patient primary acquired agammaglobulinaemia was diagnosed. Intestinal symptoms predominated. The disease was characterized by a B-cell defect. Substitution with gamma-globulin (Beriglobin) practically cured the symptoms. The pathogenesis of the disease remains unexplained. PMID:72639

  18. Diabetes and risk of community-acquired Staphylococcus aureus bacteremia

    DEFF Research Database (Denmark)

    Smit, Jesper; Søgaard, Mette; Schønheyder, Henrik Carl;

    2016-01-01

    OBJECTIVE: Patients with diabetes may experience higher risk of Staphylococcus aureus bacteremia (SAB) than patients without diabetes due to decreased immunity or coexisting morbidities. We investigated the risk of community-acquired (CA) SAB in persons with and without diabetes. DESIGN: Using...

  19. Hydrocephalus in adults with community-acquired bacterial meningitis

    NARCIS (Netherlands)

    E. Soemirien Kasanmoentalib; M.C. Brouwer; A. van der Ende; D. van de Beek

    2010-01-01

    Objective: To evaluate the occurrence, treatment, and outcome of hydrocephalus complicating community-acquired bacterial meningitis in adults. Methods: Case series from a prospective nationwide cohort study from Dutch hospitals from 2006 to 2009. Results: Hydrocephalus was diagnosed in 26 of 577 epi

  20. Management of Travel-Related Illness Acquired in Haiti.

    Science.gov (United States)

    Walters, Michele

    2015-12-01

    Management of travel-related diseases acquired in Haiti begins with the identification of tropical diseases that are prevalent in the region. Knowledge of various tropical disease incubation periods and presenting symptoms is crucial to ensure rapid triage and management of care.

  1. Characteristics of Individuals with Congenital and Acquired Deaf-Blindness

    Science.gov (United States)

    Dalby, Dawn M.; Hirdes, John P.; Stolee, Paul; Strong, J. Graham; Poss, Jeff; Tjam, Erin Y.; Bowman, Lindsay; Ashworth, Melody

    2009-01-01

    Using a standardized assessment instrument, the authors compared 182 adults with congenital deaf-blindness and those with acquired deaf-blindness. They found that those with congenital deaf-blindness were more likely to have impairments in cognition, activities of daily living, and social interactions and were less likely to use speech for…

  2. Idiopathic Acquired Hemophilia A with Undetectable Factor VIII Inhibitor

    Directory of Open Access Journals (Sweden)

    Nicholas B. Abt

    2014-01-01

    Full Text Available Objective. We present the case of a 73-year-old female, with no family or personal history of a bleeding disorder, who had a classic presentation for acquired hemophilia A. Factor VIII activity was low but detectable and a factor VIII inhibitor was undetectable. Methods. The patient’s plasma was comprehensively studied to determine the cause of the acquired coagulopathy. Using the Nijmegen modification of the Bethesda assay, no factor VIII autoantibody was measureable despite varying the incubation time from 1 to 3 hours. Results. The aPTT was prolonged at 46.8 seconds, which did not correct in the 4 : 1 mix but did with 1 : 1 mix. Using a one stage factor VIII activity assay, the FVIII activity was 16% and chromogenic FVIII activity was also 16%. The patient was treated with recombinant FVII and transfusion, significantly reducing bleeding. Long-term therapy was initiated with cyclophosphamide and prednisone with normalization of FVIII activity. Conclusions. Physicians can be presented with the challenging clinical picture of an acquired factor VIII inhibitor without a detectable inhibitor by the Bethesda assay. Standard therapy for an acquired hemophilia A should be considered.

  3. Itochu to Acquire 30% Share in Apparel Firm Shandong Ruyi

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    In its bid to expand in China's clothing sector, Itochu Corp, a Japanese trading firm which owns textile plants across Asia including China, Japan and Hong Kong, is set to acquire a 30 percent stake in Chinese apparel company Shandong Ruyi Group.

  4. Acquiring Software Design Schemas: A Machine Learning Perspective

    Science.gov (United States)

    Harandi, Mehdi T.; Lee, Hing-Yan

    1991-01-01

    In this paper, we describe an approach based on machine learning that acquires software design schemas from design cases of existing applications. An overview of the technique, design representation, and acquisition system are presented. the paper also addresses issues associated with generalizing common features such as biases. The generalization process is illustrated using an example.

  5. School Reentry for Children with Acquired Central Nervous Systems Injuries

    Science.gov (United States)

    Carney, Joan; Porter, Patricia

    2009-01-01

    Onset of acquired central nervous system (CNS) injury during the normal developmental process of childhood can have impact on cognitive, behavioral, and motor function. This alteration of function often necessitates special education programming, modifications, and accommodations in the education setting for successful school reentry. Special…

  6. 45 CFR 7.4 - Option to acquire foreign rights.

    Science.gov (United States)

    2010-10-01

    ... assignment of such rights in all or in any specified foreign countries. In case where the inventor is not... by the Commissioner of Patents, any application for a patent which may be filed in such country or... Option to acquire foreign rights. In any case where it is determined that all domestic rights should...

  7. monthly probabilities for acquiring remote sensed data of indonesia with cloud cover less than 10 , 20 and 30 percent

    OpenAIRE

    J.P. Gastellu- Etcregorry

    2013-01-01

    The Indonesian spatiotemporal cloud cover distribution was quantified with the aid of GMS, Landsat and SPOT data. Iterative interactive factorial analyses grouped pixels with similar profiles into 18 classes for all land areas. For each class, statistics of Landsat and SPOT images, grouped by class, were used to verify, calibrate and improve class profiles. This led to quantified temporal profiles of probability of acquiring remotely sensed data with 10 , 20 and 30 percent cloud cover, for an...

  8. Hospital acquired diarrhea in a burn center of Tehran

    Directory of Open Access Journals (Sweden)

    Faranak Alinejad

    2016-01-01

    Full Text Available Background and Objectives: Incidence of hospital-acquired diarrhea has increased rapidly and burn patients are at high risk of getting it. Infection with C. difficile is the most common cause of antibiotic associated diarrhea. The aim of this study was to determine the baseline characteristics and clinical presentation of hospital-acquired diarrhea and compare C. difficile and non-C. difficile diarrhea in burn patients treated at a burn center.Materials and Methods: During a 1-year study all patients with hospital-acquired diarrhea at Motahari Burn Hospital, Teh- ran, Iran enrolled in this study. We compared patients with a stool sample positive for C. difficile toxin or tracing the antigen in patients who were negative for detection of toxin in their stool sample specimens.Results: Diarrhea developed in 37 patients out of 3200 admitted patients with a mean burn size of 34.8 ±20.1%. Among them, 8 patients had a positive result for C. difficile. The mean time between antibiotic therapy and occurrence of diarrhea was 9.5 ± 6.2 days. Nine (23.7% patients died in the 7.8± 4.2 days, mostly due to co-morbidities. The mean duration of di- arrhea was 3.6 ± 2 days. Twenty two (57.9% patients were treated with oral metronidazol and eleven (28.9% patients were treated with combination of metronidazole and vancomycin, higher rate of combination therapy was seen in Clostridium difficile CDI.Conclusion: Overall, the prevalence of hospital-acquired diarrhea was 120/10,000  and 21% of them caused by infection with C. difficile. Presence of peripheral leukocytosis and colitis were the alarm sign for diagnosis of C. difficile infection. Keywords: Hospital-acquired diarrhea (HAD, Burn, Clostridium difficile infection (CDI

  9. WETLAND MAPPING WITH SAR/QUAD-POL DATA ACQUIRED DURING TANDEM-X SCIENCE PHASE

    Directory of Open Access Journals (Sweden)

    M. Mleczko

    2016-06-01

    Full Text Available The aim of this study was to exploit fully polarimetric SAR data acquired during TanDEM-X – Science Phase (2014/2015 over herbaceous wetlands of the Biebrza National Park (BbNP in North-Eastern Poland for mapping seasonally flooded grasslands and permanent natural vegetation associations. The main goal of this work was to estimate the advantage of fully polarimetric radar images (QuadPol versus alternative polarization (AltPol modes. The methodology consisted in processing of several data subsets through polarimetric decompositions of complex quad-pol datasets, classification of multitemporal backscattering images, complementing backscattering images with Shannon Entropy, exploitation of interferometric coherence from tandem operations. In each case the multidimensional stack of images has been classified using ISODATA unsupervised clustering algorithm. With 6 QUAD-POL TSX/TDX acquisitions it was possible to distinguish correctly 5 thematic classes related to their water regime: permanent water bodies, temporarily flooded areas, wet grasslands, dry grasslands and common reed. This last category was possible to distinguish from deciduous forest only with Yamaguchi 4 component decomposition. The interferometric coherence calculated for tandem pairs turned out not so efficient as expected for this wetland mapping.

  10. Wetland Mapping with Quad-Pol Data Acquired during Tandem-X Science Phase

    Science.gov (United States)

    Mleczko, M.; Mroz, M.; Fitrzyk, M.

    2016-06-01

    The aim of this study was to exploit fully polarimetric SAR data acquired during TanDEM-X - Science Phase (2014/2015) over herbaceous wetlands of the Biebrza National Park (BbNP) in North-Eastern Poland for mapping seasonally flooded grasslands and permanent natural vegetation associations. The main goal of this work was to estimate the advantage of fully polarimetric radar images (QuadPol) versus alternative polarization (AltPol) modes. The methodology consisted in processing of several data subsets through polarimetric decompositions of complex quad-pol datasets, classification of multitemporal backscattering images, complementing backscattering images with Shannon Entropy, exploitation of interferometric coherence from tandem operations. In each case the multidimensional stack of images has been classified using ISODATA unsupervised clustering algorithm. With 6 QUAD-POL TSX/TDX acquisitions it was possible to distinguish correctly 5 thematic classes related to their water regime: permanent water bodies, temporarily flooded areas, wet grasslands, dry grasslands and common reed. This last category was possible to distinguish from deciduous forest only with Yamaguchi 4 component decomposition. The interferometric coherence calculated for tandem pairs turned out not so efficient as expected for this wetland mapping.

  11. CCD-Based XRD/XRF for Determining Environmental Mineralogy on Mars

    Science.gov (United States)

    Vaniman, D. T.; Bish, D. L.; Blake, D. F.; Chipera, S. J.

    2000-01-01

    Health effects from Martian dusts will be a concern for any manned Mars missions. Nuisance dusts plagued the Apollo astronauts, but dusts of more hazardous mineralogy, in habitats occupied by Mars astronauts weakened by a long-duration mission, may be more than a nuisance. Chemical hazards in Martian regolith attributable to S, Cl, Br, Cd, and Pb are known or strongly suspected to be present, but terrestrial studies of the health effects of dusts indicate that accurate determination of mineralogy is a critical factor in evaluating inhalation hazards. Mineral inhalation hazards such as the Group-I carcinogenic zeolite erionite, which is demonstrated to cause mesothelioma, cannot be identified by chemical analysis alone. Studies of palagonite analogs raise the possibility that erionite may occur on Mars. In addition to health effects concerns, environmental mineralogy has significant importance in resource extraction, groundwater use, and sustained agriculture. The high sulfur and chlorine content of Martian regolith will affect all of these uses, but the nature of mineralogic reservoirs for S and Cl will determine their uptake and concentration in extracted groundwater and in agricultural applications of regolith. Wet chemistry experiments planned for the Mars Environmental Compatibility Assessment (MECA) will define some of the consequences of water/soil interaction, but an understanding of the mineralogic basis for water-rock reactions is needed to understand the mechanisms of reaction and to apply the results of a few experiments to larger scales and different conditions.

  12. Whole mouse cryo-imaging

    Science.gov (United States)

    Wilson, David; Roy, Debashish; Steyer, Grant; Gargesha, Madhusudhana; Stone, Meredith; McKinley, Eliot

    2008-03-01

    The Case cryo-imaging system is a section and image system which allows one to acquire micron-scale, information rich, whole mouse color bright field and molecular fluorescence images of an entire mouse. Cryo-imaging is used in a variety of applications, including mouse and embryo anatomical phenotyping, drug delivery, imaging agents, metastastic cancer, stem cells, and very high resolution vascular imaging, among many. Cryo-imaging fills the gap between whole animal in vivo imaging and histology, allowing one to image a mouse along the continuum from the mouse -> organ -> tissue structure -> cell -> sub-cellular domains. In this overview, we describe the technology and a variety of exciting applications. Enhancements to the system now enable tiled acquisition of high resolution images to cover an entire mouse. High resolution fluorescence imaging, aided by a novel subtraction processing algorithm to remove sub-surface fluorescence, makes it possible to detect fluorescently-labeled single cells. Multi-modality experiments in Magnetic Resonance Imaging and Cryo-imaging of a whole mouse demonstrate superior resolution of cryo-images and efficiency of registration techniques. The 3D results demonstrate the novel true-color volume visualization tools we have developed and the inherent advantage of cryo-imaging in providing unlimited depth of field and spatial resolution. The recent results continue to demonstrate the value cryo-imaging provides in the field of small animal imaging research.

  13. Imaging with coincidence detectors

    International Nuclear Information System (INIS)

    The development of a dual-detector, single photon emission computed tomography (SPECT) system that could be modified to perform coincidence imaging of positron-emitting radiotracers has resulted in a renaissance in the nuclear medicine community. In 1996, ADAC Laboratories introduced their Molecula Coincidence Detection (MCD) system at the Society of Nuclear Medicine Annual General Meeting in Denver. This ushered in a new era in nuclear medicine imaging. The ability of these coincidence systems to image 18FDG promises to make this type of imaging 'just another nuclear medicine procedure', possible within the next decade. This advancement is arguably the biggest news in nuclear medicine since the development of SPECT. In August 1997, Lion's Gate Hospital in North Vancouver acquired the MCD upgrade to their ADAC Vertex camera - the first and only to date in Canada. This article introduces coincidence imaging and describes the experiences of those pioneering the use of this new modality in Canada

  14. Evaluation of Geometric Accuracy and Image Quality of an On-Board Imager (OBI)

    OpenAIRE

    Djordjevic, Milos

    2007-01-01

    In this project several tests were performed to evaluate the performance of an On-Board Imager® (OBI) mounted on a clinical linear accelerator. The measurements were divided into three parts; geometric accuracy, image registration and couch shift accuracy, and image quality. A cube phantom containing a radiation opaque marker was used to study the agreement with treatment isocenter for both kV-images and cone-beam CT (CBCT) images. The long term stability was investigated by acquiring frontal...

  15. Three-dimensional distribution analysis of platinum, palladium and rhodium in auto catalytic converters using imaging-mode laser-induced breakdown spectrometry

    Science.gov (United States)

    Lucena, Patricia; Laserna, J. Javier

    2001-02-01

    Laser-induced breakdown spectrometry (LIBS) is reported here as an effective technique to describe the volume distribution of platinum, rhodium and palladium in catalytic converters installed in motor vehicles. Using the second harmonic output of a Nd:YAG laser and a CCD-based atomic emission spectrometer, LIBS is used in multielemental, imaging-mode to permit the simultaneous analysis of the several elements present in the converter, including the internal standard. The data are reported with a lateral resolution of 1.75 mm over a fresh catalytic structure which is 128 mm long. The concentrational variability of the platinum group metals (PGMs) varies in the range ˜3-23% relative standard deviation depending on the element, the substrate and the direction investigated. The causes of the dispersion observed are discussed.

  16. Generalisation after treatment of acquired spelling impairments: A review.

    Science.gov (United States)

    Krajenbrink, Trudy; Nickels, Lyndsey; Kohnen, Saskia

    2015-01-01

    This paper provides a comprehensive review of treatment studies of acquired dysgraphia and the occurrence of generalisation after this treatment. The aim is to examine what determines the occurrence of generalisation by investigating the link between the level of impairment, the method of treatment, and the outcome of therapy. We present the outcomes of treatment with regard to generalisation in 40 treatment studies. We derive general principles of generalisation which provide us with a better understanding of the mechanism of generalisation: (1) Direct treatment effects on representations or processes; (2) interactive processing and summation of activation; and (3) strategies and compensatory skills. We discuss the implications of these findings for our understanding of the cognitive processes used for spelling. Finally, we provide suggestions for the direction of further research into this important area, as a better understanding of the mechanism of generalisation could maximise treatment effects for an individual with acquired dysgraphia. PMID:25403342

  17. Microsoft Acquired Nokia in Unipolar Operating System Market

    Directory of Open Access Journals (Sweden)

    Netra Pal Singh

    2014-09-01

    Full Text Available The recent big tickets include Microsoft acquiring part of Nokia for US$ 7.2 billion, Verizon buy 45% stake in Vodafone for US$130 billion, Google acquiring Motorola for 12.5 billion. These buyouts are analyzed and commented by experts of the industry. This research paper attempted to collate their view in the context of Microsoft and Nokia deal on six parameters. These parameters are (i reasons for the downfall of the Nokia market share, (ii general comments of the experts, (iii similarities / dissimilarities of past and business models of the smartphone business, (iv reasons for Microsoft to buy out Nokia, (vi impact of buyout on Microsoft, Nokia, consumers and markets.

  18. Multinational Exploration of Acquired R&D Activities

    DEFF Research Database (Denmark)

    Gammelgaard, Jens

    2004-01-01

    This paper presents the results of a survey of 54 Danish multinational corporations that haveacquired activities abroad. The role of the acquired R&D units was the focus of the survey,particularly with respect to the schism between basic and applied R&D, and the schismbetween autonomous and netwo...... a combination of basic andnetwork-oriented R&D activities when focusing on capability development.Keywords: Acquisition; Research and Development (R&D), Basic R&D, Applied R&D,Autonomy, Network, Capabilities.......This paper presents the results of a survey of 54 Danish multinational corporations that haveacquired activities abroad. The role of the acquired R&D units was the focus of the survey,particularly with respect to the schism between basic and applied R&D, and the schismbetween autonomous and network...

  19. Label-acquired magnetorotation for biosensing: An asynchronous rotation assay

    Energy Technology Data Exchange (ETDEWEB)

    Hecht, Ariel, E-mail: hecht@umich.ed [University of Michigan, Department of Biomedical Engineering, 2200 Bonisteel, Ann Arbor, MI 48109-2099 (United States); University of Michigan, Department of Chemistry, 930 North University, Ann Arbor, MI 48109-1055 (United States); Kinnunen, Paivo, E-mail: pkkinn@umich.ed [University of Michigan, Department of Chemistry, 930 North University, Ann Arbor, MI 48109-1055 (United States); University of Michigan, Applied Physics Program, 2477 Randall Laboratory, Ann Arbor, MI 48109-1120 (United States); McNaughton, Brandon, E-mail: bmcnaugh@umich.ed [University of Michigan, Department of Biomedical Engineering, 2200 Bonisteel, Ann Arbor, MI 48109-2099 (United States); University of Michigan, Department of Chemistry, 930 North University, Ann Arbor, MI 48109-1055 (United States); University of Michigan, Applied Physics Program, 2477 Randall Laboratory, Ann Arbor, MI 48109-1120 (United States); Kopelman, Raoul, E-mail: kopelman@umich.ed [University of Michigan, Department of Biomedical Engineering, 2200 Bonisteel, Ann Arbor, MI 48109-2099 (United States); University of Michigan, Department of Chemistry, 930 North University, Ann Arbor, MI 48109-1055 (United States); University of Michigan, Applied Physics Program, 2477 Randall Laboratory, Ann Arbor, MI 48109-1120 (United States)

    2011-02-15

    This paper presents a novel application of magnetic particles for biosensing, called label-acquired magnetorotation (LAM). This method is based on a combination of the traditional sandwich assay format with the asynchronous magnetic bead rotation (AMBR) method. In label-acquired magnetorotation, an analyte facilitates the binding of a magnetic label bead to a nonmagnetic solid phase sphere, forming a sandwich complex. The sandwich complex is then placed in a rotating magnetic field, where the rotational frequency of the sandwich complex is a function of the amount of analyte attached to the surface of the sphere. Here, we use streptavidin-coated beads and biotin-coated particles as analyte mimics, to be replaced by proteins and other biological targets in future work. We show this sensing method to have a dynamic range of two orders of magnitude.

  20. Acquiring Word-Meaning Mappings for Natural Language Interfaces

    CERN Document Server

    Thompson, C

    2011-01-01

    This paper focuses on a system, WOLFIE (WOrd Learning From Interpreted Examples), that acquires a semantic lexicon from a corpus of sentences paired with semantic representations. The lexicon learned consists of phrases paired with meaning representations. WOLFIE is part of an integrated system that learns to transform sentences into representations such as logical database queries. Experimental results are presented demonstrating WOLFIE's ability to learn useful lexicons for a database interface in four different natural languages. The usefulness of the lexicons learned by WOLFIE are compared to those acquired by a similar system, with results favorable to WOLFIE. A second set of experiments demonstrates WOLFIE's ability to scale to larger and more difficult, albeit artificially generated, corpora. In natural language acquisition, it is difficult to gather the annotated data needed for supervised learning; however, unannotated data is fairly plentiful. Active learning methods attempt to select for annotation...

  1. Acquired vulvar lymphangioma circumscriptum after cervical cancer treatment: Case report.

    Science.gov (United States)

    Valente, Kari; Montgomery, Kathleen; Schultenover, Stephen; Desouki, Mohamed Mokhtar

    2016-04-01

    Vulvar lymphangioma circumscriptum (LC) is a rare entity which may present as a painful, warty lesion. In contrast to the congenital form, which occurs in children, the acquired form arises in older adults and may be associated with infection, Crohn's disease, or prior pelvic/regional surgery. We present a case of acquired LC of the vulva in a 55-year-old woman who presented with a 3-4 year history of vulvar pain following chemotherapy, radiation, and brachytherapy for cervical cancer. Vulvar shave biopsies followed by excision revealed a thickened dermis with epidermal hyperkeratosis, parakeratosis, elongated rete ridges and dilated lymphatic channels containing eosinophilic material and scattered thrombi. The differential diagnosis for this unusual lesion includes more common conditions such as condyloma acuminatum, fungating squamous cell carcinoma and molluscum contagiosum. It is important to recognize the clinical presentation as well as the distinct histological appearance of this rare benign entity. PMID:27331134

  2. Improving survival among Brazilian children with perinatally-acquired AIDS

    Directory of Open Access Journals (Sweden)

    Luiza Harunari Matida

    2004-12-01

    Full Text Available Brazil was the first developing country to provide free, universal access to antiretroviral treatment for AIDS patients. The Brazilian experience thus provides the first evidence regarding the impact of such treatment on the survival of perinatally acquired AIDS cases in the developing world. MATERIAL AND METHODS: This retrospective cohort study used medical record reviews to examine characteristics and trends in the survival of a representative sample of 914 perinatally acquired AIDS cases in 10 Brazilian cities diagnosed between 1983 and 1998. RESULTS: Survival time increased steadily and substantially. Whereas half of the children died within 20 months of diagnosis at the beginning of the epidemic, 75% of children diagnosed in 1997 and 1998 were still alive after four years of follow-up. CONCLUSIONS: Advances in management and treatment have made a great difference in the survival of Brazilian children with AIDS. These results argue strongly for making such treatment available to children in the entire developing world.

  3. Acquired immunodeficiency syndrome associated with blood-product transfusions

    Energy Technology Data Exchange (ETDEWEB)

    Jett, J.R.; Kuritsky, J.N.; Katzmann, J.A.; Homburger, H.A.

    1983-11-01

    A 53-year-old white man had fever, malaise, and dyspnea on exertion. His chest roentgenogram was normal, but pulmonary function tests showed impaired diffusion capacity and a gallium scan showed marked uptake in the lungs. Results of an open-lung biopsy documented Pneumocystis carinii pneumonia. Immunologic test results were consistent with the acquired immunodeficiency syndrome. The patient denied having homosexual contact or using intravenous drugs. Twenty-nine months before the diagnosis of pneumocystis pneumonia was made, the patient had had 16 transfusions of whole blood, platelets, and fresh-frozen plasma during coronary artery bypass surgery at another medical center. This patient is not a member of any currently recognized high-risk group and is believed to have contracted the acquired immunodeficiency syndrome from blood and blood-product transfusions.

  4. Тhe features of severe community acquired pneumonia

    Directory of Open Access Journals (Sweden)

    Avramenko I.V.

    2015-06-01

    Full Text Available Based on data from a prospective analysis for the year of observation, the article presents information about the features of severe community acquired pneumonia in patients who were hospitalized at the department of pulmonology (or therapy, as well as department of the intensive care from three teaching hospitals in Dnepropetrovsk, namely "Dnipropetrovsk City Hospital №6», "Dnipropetrovsk City Hospital №2», "Dnipropetrovsk City Hospital №16», which are the clinical ones of "Dnepropetrovsk Medical Academy of the Ministry of Health Ukraine". Dependence of the severity of the condition shown on duration of illness before admission, features of season character of disease. The effect of breathing exercises on the course of the disease. The results can be the basis for a more personal approach to the development of diagnostic and therapeutic programs for patients with severe community-acquired pneumonia.

  5. Echo particle image velocimetry.

    Science.gov (United States)

    DeMarchi, Nicholas; White, Christopher

    2012-12-27

    The transport of mass, momentum, and energy in fluid flows is ultimately determined by spatiotemporal distributions of the fluid velocity field.(1) Consequently, a prerequisite for understanding, predicting, and controlling fluid flows is the capability to measure the velocity field with adequate spatial and temporal resolution.(2) For velocity measurements in optically opaque fluids or through optically opaque geometries, echo particle image velocimetry (EPIV) is an attractive diagnostic technique to generate "instantaneous" two-dimensional fields of velocity.(3,4,5,6) In this paper, the operating protocol for an EPIV system built by integrating a commercial medical ultrasound machine(7) with a PC running commercial particle image velocimetry (PIV) software(8) is described, and validation measurements in Hagen-Poiseuille (i.e., laminar pipe) flow are reported. For the EPIV measurements, a phased array probe connected to the medical ultrasound machine is used to generate a two-dimensional ultrasound image by pulsing the piezoelectric probe elements at different times. Each probe element transmits an ultrasound pulse into the fluid, and tracer particles in the fluid (either naturally occurring or seeded) reflect ultrasound echoes back to the probe where they are recorded. The amplitude of the reflected ultrasound waves and their time delay relative to transmission are used to create what is known as B-mode (brightness mode) two-dimensional ultrasound images. Specifically, the time delay is used to determine the position of the scatterer in the fluid and the amplitude is used to assign intensity to the scatterer. The time required to obtain a single B-mode image, t, is determined by the time it take to pulse all the elements of the phased array probe. For acquiring multiple B-mode images, the frame rate of the system in frames per second (fps) = 1/δt. (See 9 for a review of ultrasound imaging.) For a typical EPIV experiment, the frame rate is between 20-60 fps

  6. Acquired Fanconi syndrome in patients with Legionella pneumonia

    OpenAIRE

    Kinoshita-Katahashi, Naoko; Fukasawa, Hirotaka; Ishigaki, Sayaka; Isobe, Shinsuke; Imokawa, Shiro; Fujigaki, Yoshihide; Furuya, Ryuichi

    2013-01-01

    Background Hyponatremia is often observed in patients with Legionella pneumonia. However, other electrolyte abnormalities are uncommon and the mechanism remains to be clarified. Case presentation We experienced two male cases of acquired Fanconi syndrome associated with Legionella pneumonia. The laboratory findings at admission showed hypophosphatemia, hypokalemia, hypouricemia and/or hyponatremia. In addition, they had the generalized dysfunction of the renal proximal tubules presenting decr...

  7. Acquiring knowledge: Bloomsbury's foray into the academic and online markets

    OpenAIRE

    Barnsley, Connor Reny

    2012-01-01

    Bloomsbury Publishing Plc has recently expanded into the academic market, acquiring six academic publishing houses since 2006 and creating their own imprint, Bloomsbury Academic. The London-based publishing house had been heavily investing in e-book publications and experimenting with an Open Access model. This report examines how Bloomsbury has successfully invested the revenue generated by the Harry Potter series into new academic and digital business ventures. The firm’s growth and expans...

  8. Intensive Care Unit Acquired Weakness: Under or Overdiagnosed?

    OpenAIRE

    Morgado, S; Moura, S.

    2010-01-01

    Intensive care unit-acquired weakness (ICU-AW) is recognized as an important and common clinical problem, associated with an increased morbidity in critical ill patients. This muscle weakness has been described in a wide range of clinical settings and therefore, has many different terminologies such as “critical illness myopathy – CIM”, “critical illness polyneuropathy - CIP”, “acute quadriplegic myopathy”, among others. Nowadays, these designations are considered somewhat restric...

  9. Improving Acquired Immunodeficiency Syndrome Related Cancer Outcomes through International Collaboration

    Institute of Scientific and Technical Information of China (English)

    Mostafa Nokta

    2011-01-01

    @@ The spectrum of cancers seen in human immunodeficiency virus (HIV)infected individuals is diverse and complex,and reflects an ever-changing HIV epidemic.In parts of the world where combination antiretroviral therapy (cART) is available,HIV-infected patients are living longer and are less likely to die of acquired immunodeficiency syndrome (AIDS)defining malignancies within a year or two of developing AIDS.

  10. Nodes of Ranvier and Paranodes in Chronic Acquired Neuropathies

    OpenAIRE

    Carmen Cifuentes-Diaz; Odile Dubourg; Theano Irinopoulou; Marc Vigny; Sylvie Lachkar; Laurence Decker; Patrick Charnay; Natalia Denisenko; Thierry Maisonobe; Jean-Marc Léger; Karine Viala; Jean-Jacques Hauw; Jean-Antoine Girault

    2011-01-01

    Chronic acquired neuropathies of unknown origin are classified as chronic inflammatory demyelinating polyneuropathies (CIDP) and chronic idiopathic axonal polyneuropathies (CIAP). The diagnosis can be very difficult, although it has important therapeutic implications since CIDP can be improved by immunomodulating treatment. The aim of this study was to examine the possible abnormalities of nodal and paranodal regions in these two types of neuropathies. Longitudinal sections of superficial per...

  11. Procedure selection for the flexible adult acquired flatfoot deformity.

    Science.gov (United States)

    Hentges, Matthew J; Moore, Kyle R; Catanzariti, Alan R; Derner, Richard

    2014-07-01

    Adult acquired flatfoot represents a spectrum of deformities affecting the foot and the ankle. The flexible, or nonfixed, deformity must be treated appropriately to decrease the morbidity that accompanies the fixed flatfoot deformity or when deformity occurs in the ankle joint. A comprehensive approach must be taken, including addressing equinus deformity, hindfoot valgus, forefoot supinatus, and medial column instability. A combination of osteotomies, limited arthrodesis, and medial column stabilization procedures are required to completely address the deformity.

  12. Surgical treatment of the adult acquired flexible flatfoot.

    Science.gov (United States)

    Van Gestel, Lise; Van Bouwel, Saskia; Somville, Johan

    2015-06-01

    In this review article, the authors give an overview of the currently available soft tissue and bony procedures in the treatment of the adult acquired flexible flatfoot. Instead of starting from the classification for posterior tibial tendon dysfunction, described by Johnson and Storm, the authors address the flatfoot from a more anatomical point of view. Based on this, they will try to define a treatment algorithm.

  13. Arabidopsis map kinase 4 negatively regulates systemic acquired resistance

    DEFF Research Database (Denmark)

    Brodersen, P; Johansen, Bo; Petersen, M;

    2000-01-01

    Transposon inactivation of Arabidopsis MAP kinase 4 produced the mpk4 mutant exhibiting constitutive systemic acquired resistance (SAR) including elevated salicylic acid (SA) levels, increased resistance to virulent pathogens, and constitutive pathogenesis-related gene expression shown by Northern...... of NPR1. PDF1.2 and THI2.1 gene induction by jasmonate was blocked in mpk4 expressing NahG, suggesting that MPK4 is required for jasmonic acid-responsive gene expression....

  14. Acquiring language proficiency among Chinese immigrant women in Metro Vancouver

    OpenAIRE

    Ling, Trixie

    2011-01-01

    This study examines the challenges in acquiring English language proficiency among Chinese immigrant women in Metro Vancouver and the impact on their social and economic integration in the community. This research suggests that these women can benefit from informal language learning. Through semi-structured interviews and photovoice research, the women share their experiences of language barriers and the impact on daily lives. The thematic analysis shows that women with limited English langua...

  15. Psychotherapy after acquired brain injury: Is less more?

    Directory of Open Access Journals (Sweden)

    Rudi Coetzer

    2014-02-01

    Full Text Available This paper considers the challenges and dilemmas facing psychotherapists working with neurological patients, and in particular those who work in the context of under-resourced brain injury rehabilitation healthcare systems. Through the subjective process of reflective practice integral to clinical supervision, the author attempts to identify five core aspects of psychotherapy intended to augment post-acute long- term rehabilitation programmes and interventions after acquired brain injury.

  16. Acquire information about neutrino parameters by detecting supernova neutrinos

    OpenAIRE

    Huang, Ming-Yang; Guo, Xin-Heng; Young, Bing-Lin

    2010-01-01

    We consider the supernova shock effects, the Mikheyev-Smirnov-Wolfenstein (MSW) effects, the collective effects, and the Earth matter effects in the detection of type II supernova neutrinos on the Earth. It is found that the event number of supernova neutrinos depends on the neutrino mass hierarchy, the neutrino mixing angle $\\theta_{13}$, and neutrino masses. Therefore, we propose possible methods to identify the mass hierarchy and acquire information about $\\theta_{13}$ and neutrino masses ...

  17. Escherichia coli and Community-acquired Gastroenteritis, Melbourne, Australia

    OpenAIRE

    Robins-Browne, Roy M.; Bordun, Anne-Marie; Tauschek, Marija; Bennett-Wood, Vicki R.; Russell, Jacinta; Oppedisano, Frances; Lister, Nicole A.; Bettelheim, Karl A.; Fairley, Christopher K.; Sinclair, Martha I; Hellard, Margaret E

    2004-01-01

    As part of a study to determine the effects of water filtration on the incidence of community-acquired gastroenteritis in Melbourne, Australia, we examined fecal samples from patients with gastroenteritis and asymptomatic persons for diarrheagenic strains of Escherichia coli. Atypical strains of enteropathogenic E. coli (EPEC) were the most frequently identified pathogens of all bacterial, viral, and parasitic agents in patients with gastroenteritis. Moreover, atypical EPEC were more common i...

  18. Tacalcitol in the Treatment of Acquired Perforating Collagenosis

    OpenAIRE

    Escribano-Stablé, J.C.; Doménech, C.; Matarredona, J.; Pascual, J.C.; Jaen, A; Vicente, J.

    2014-01-01

    Acquired perforating collagenosis (APC) is a rare perforating dermatosis characterized by transepidermal collagen elimination. We describe a 65-year-old patient, with long-standing type 2 diabetes mellitus and a 2-year history of itchy hyperkeratotic nodules situated on the back, who was subsequently diagnosed with APC. Treatment included topical corticosteroids and antihistamines, without improvement of the lesions. However, therapy with topical tacalcitol administered for 2 months produced ...

  19. Tacalcitol in the Treatment of Acquired Perforating Collagenosis

    Directory of Open Access Journals (Sweden)

    J.C. Escribano-Stablé

    2014-02-01

    Full Text Available Acquired perforating collagenosis (APC is a rare perforating dermatosis characterized by transepidermal collagen elimination. We describe a 65-year-old patient, with long-standing type 2 diabetes mellitus and a 2-year history of itchy hyperkeratotic nodules situated on the back, who was subsequently diagnosed with APC. Treatment included topical corticosteroids and antihistamines, without improvement of the lesions. However, therapy with topical tacalcitol administered for 2 months produced a significant response leading to complete remission of APC.

  20. Nuclear EGFR Contributes to Acquired Resistance to Cetuximab

    OpenAIRE

    Li, Chunrong; Iida, Mari; Dunn, Emily F.; Ghia, Amol J.; Wheeler, Deric L

    2009-01-01

    Epidermal growth factor receptor (EGFR) is a ubiquitously expressed receptor tyrosine kinase involved in the etiology of several human cancers. Cetuximab is an EGFR blocking-antibody that has been approved for the treatment of patients with cancers of the head and neck (HNSCC) and metastatic colorectal cancer (mCRC). Previous reports have shown that EGFR translocation to the nucleus is associated with cell proliferation. Here we investigated mechanisms of acquired resistance to cetuximab usin...

  1. Cognitive rehabilitation in children with acquired brain injuries

    OpenAIRE

    Hagberg-van't Hooft, Ingrid

    2005-01-01

    Deficits in attention, memory and executive functions are the most common cognitive dysfunctions after acquired brain injuries (ABI) and may have a major negative influence on academic and social adjustment. Neuropsychological measures can assess these dysfunctions and shortcomings in academic and social life, but there is a great need for new efficacious cognitive treatment programmes. The main aims of this thesis were to evaluate the direct and maintained effects of a ...

  2. Early neurovascular uncoupling in the brain during community acquired pneumonia

    OpenAIRE

    Rosengarten, Bernhard; Krekel, Dennis; Kuhnert, Stefan; Schulz, Richard

    2012-01-01

    Introduction Sepsis leads to microcirculatory dysfunction and therefore a disturbed neurovascular coupling in the brain. To investigate if the dysfunction is also present in less severe inflammatory diseases we studied the neurovascular coupling in patients suffering from community acquired pneumonia. Methods Patients were investigated in the acute phase of pneumonia and after recovery. The neurovascular coupling was investigated with a simultaneous electroencephalogram (EEG)-Doppler techniqu...

  3. A case report of inhalation anthrax acquired naturally

    OpenAIRE

    Azarkar, Zohreh; Zare Bidaki, Majid

    2016-01-01

    Background Anthrax is a zoonotic occupational disease caused by Bacillus anthracis, a rod-shaped immobile aerobic gram-positive bacteria with spore. Anthrax occurs in humans randomly and with low frequency. Most cases of anthrax are acquired through contact with infected animals or contaminated animal products. This old disease became particularly important since 2001 that the biological spores were exploited in America. Depending on the transmission method of the disease, clinical manifestat...

  4. Cerebral computed tomography in men with acquired immunodeficiency syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Brun, B.; Boesen, F.; Gerstoft, J.; Nielsen, J.O.; Praestholm, J.

    Cerebral CT scannings were performed in 19 homosexual men with the acquired immunodeficiency syndrome (AIDS). Nearly half of them (9 patients) had cortical atrophy. Three patients with toxoplasmosis had cerebral pathology, in two of them with ring enhancement while the third had an ill-defined nonspecific lesion with slight heterogeneous enhancement without ring formation. Two patients with multifocal leucoencephalopathy and non-Hodgkin's lymphoma, respectively, presented non-enhancing, low attenuating lesions at CT.

  5. Clinical features of endemic community-acquired psittacosis

    OpenAIRE

    J.M. Branley; Weston, K M; England, J; Dwyer, D E; Sorrell, T C

    2014-01-01

    Following a large outbreak of community-acquired psittacosis in 2002 in residents of the Blue Mountains, New South Wales, Australia, we reviewed new cases in this area over a 7-year period from 2003 to 2009. Using the 2010 criteria from the Centers for Disease Control National Notifiable Diseases Surveillance System, 85 patients with possible psittacosis were identified, of which 48 were identified as definite or probable infection. Clinical features of these cases are summarized. In addition...

  6. Acquired immunologic tolerance: with particular reference to transplantation

    OpenAIRE

    Starzl, Thomas E.

    2007-01-01

    The first unequivocally successful bone marrow cell transplantation in humans was recorded in 1968 by the University of Minnesota team of Robert A. Good (Gatti et al. Lancet 2: 1366–1369, 1968). This achievement was a direct extension of mouse models of acquired immunologic tolerance that were established 15 years earlier. In contrast, organ (i.e. kidney) transplantation was accomplished precociously in humans (in 1959) before demonstrating its feasibility in any experimental model and in the...

  7. Acquiring Ecg Signals And Analysing For Different Heart Ailments

    OpenAIRE

    B.Sravanthi; Seshukumar Chegu

    2015-01-01

    This paper describes and focuses on acquiring and identification of cardiac diseases using ECG waveform in LabVIEW software, which would bridge the gap between engineers and medical physicians. This model work collects the waveform of an affected person. The waveform is analyzed for diseases and then a report is sent to the doctor through mail. Initially the waveforms are collected from the person using EKG sensor with the help of surface electrodes and the hardware controlled by ...

  8. Community-Acquired Pneumonia in Children: A Multidisciplinary Consensus Review

    OpenAIRE

    Low, Donald E.; Kellner, James D; Allen, Upton; Boucher, Francois D; Kovesi, Thomas; Riesman, John; Davidson, Ross; Joanne M Langley

    2003-01-01

    Community-acquired pneumonia (CAP) is common among children and may have viral, bacterial or, occasionally, other causes. The etiology is complex, with age-related trends, and differs from that in adult CAP, necessitating different management guidelines. There is an absence of current guidelines for the management of pediatric CAP (PCAP) that take into account changing etiologies, antimicrobial-resistance issues and the use of newly licensed antimicrobials. The present review does not provide...

  9. Acquired Surface Alexia in Spanish: A Case Report

    OpenAIRE

    Ferreres, Aldo R.; Macarena Martinez Cuitiño; Alicia Olmedo

    2005-01-01

    This paper reports a case study of acquired surface alexia in Spanish and discusses the most suitable tests to detect this syndrome in a writing system that is very regular for reading at the segmental and supra-segmental levels. Patient MM has surface alexia characterized by quantitatively good performance in reading words and pseudowords; accurate but slow and syllabic reading of words, nonwords and sentences; good performance in lexical decision tasks including words and nonwords; errors i...

  10. Targets for Combating the Evolution of Acquired Antibiotic Resistance

    OpenAIRE

    Culyba, Matthew J.; Mo, Charlie Y.; Kohli, Rahul M.

    2015-01-01

    Bacteria possess a remarkable ability to rapidly adapt and evolve in response to antibiotics. Acquired antibiotic resistance can arise by multiple mechanisms but commonly involves altering the target site of the drug, enzymatically inactivating the drug, or preventing the drug from accessing its target. These mechanisms involve new genetic changes in the pathogen leading to heritable resistance. This recognition underscores the importance of understanding how such genetic changes can arise. H...

  11. Severe Dermatophytosis and Acquired or Innate Immunodeficiency: A Review

    OpenAIRE

    Claire Rouzaud; Roderick Hay; Olivier Chosidow; Nicolas Dupin; Anne Puel; Olivier Lortholary; Fanny Lanternier

    2015-01-01

    Dermatophytes are keratinophilic fungi responsible for benign and common forms of infection worldwide. However, they can lead to rare and severe diseases in immunocompromised patients. Severe forms include extensive and/or invasive dermatophytosis, i.e., deep dermatophytosis and Majocchi’s granuloma. They are reported in immunocompromised hosts with primary (autosomal recessive CARD9 deficiency) or acquired (solid organ transplantation, autoimmune diseases requiring immunosuppressive treatmen...

  12. Arabidopsis MAP kinase 4 negatively regulates systemic acquired resistance

    DEFF Research Database (Denmark)

    Petersen, M.; Brodersen, P.; Naested, H.;

    2000-01-01

    Transposon inactivation of Arabidopsis MAP kinase 4 produced the mpk4 mutant exhibiting constitutive systemic acquired resistance (SAR) including elevated salicylic acid (SA) revels, increased resistance to virulent pathogens, and constitutive pathogenesis-related gene expression shown by Northern...... of NPR1. PDF1.2 and THI2.1 gene induction by jasmonate was blocked in mpk4 expressing NahG, suggesting that MPK4 is required for jasmonic acid-responsive gene expression....

  13. Preliminary images from an adaptive imaging system.

    Science.gov (United States)

    Griffiths, J A; Metaxas, M G; Pani, S; Schulerud, H; Esbrand, C; Royle, G J; Price, B; Rokvic, T; Longo, R; Asimidis, A; Bletsas, E; Cavouras, D; Fant, A; Gasiorek, P; Georgiou, H; Hall, G; Jones, J; Leaver, J; Li, G; Machin, D; Manthos, N; Matheson, J; Noy, M; Ostby, J M; Psomadellis, F; van der Stelt, P F; Theodoridis, S; Triantis, F; Turchetta, R; Venanzi, C; Speller, R D

    2008-06-01

    I-ImaS (Intelligent Imaging Sensors) is a European project aiming to produce real-time adaptive X-ray imaging systems using Monolithic Active Pixel Sensors (MAPS) to create images with maximum diagnostic information within given dose constraints. Initial systems concentrate on mammography and cephalography. In our system, the exposure in each image region is optimised and the beam intensity is a function of tissue thickness and attenuation, and also of local physical and statistical parameters in the image. Using a linear array of detectors, the system will perform on-line analysis of the image during the scan, followed by optimisation of the X-ray intensity to obtain the maximum diagnostic information from the region of interest while minimising exposure of diagnostically less important regions. This paper presents preliminary images obtained with a small area CMOS detector developed for this application. Wedge systems were used to modulate the beam intensity during breast and dental imaging using suitable X-ray spectra. The sensitive imaging area of the sensor is 512 x 32 pixels 32 x 32 microm(2) in size. The sensors' X-ray sensitivity was increased by coupling to a structured CsI(Tl) scintillator. In order to develop the I-ImaS prototype, the on-line data analysis and data acquisition control are based on custom-developed electronics using multiple FPGAs. Images of both breast tissues and jaw samples were acquired and different exposure optimisation algorithms applied. Results are very promising since the average dose has been reduced to around 60% of the dose delivered by conventional imaging systems without decrease in the visibility of details. PMID:18291697

  14. Acquired cancer stem cell phenotypes through Oct4-mediated dedifferentiation

    Science.gov (United States)

    Kumar, Suresh M.; Liu, Shujing; Lu, Hezhe; Zhang, Hongtao; Zhang, Paul J.; Gimotty, Phyllis A.; Guerra, Matthew; Guo, Wei; Xu, Xiaowei

    2012-01-01

    There is enormous interest to target cancer stem cells (CSCs) for clinical treatment because these cells are highly tumorigenic and resistant to chemotherapy. Oct4 is expressed by CSC-like cells in different types of cancer. However, function of Oct4 in tumor cells is unclear. In this study, we showed that expression of Oct4 gene or transmembrane delivery of Oct4 protein promoted dedifferentiation of melanoma cells to CSC-like cells. The dedifferentiated melanoma cells showed significantly decreased expression of melanocytic markers and acquired the ability to form tumor spheroids. They showed markedly increased resistance to chemotherapeutic agents and hypoxic injury. In the subcutaneous xenograft and tail vein injection assays, these cells had significantly increased tumorigenic capacity. The dedifferentiated melanoma cells acquired features associated with CSCs such as multipotent differentiation capacity and expression of melanoma CSC markers such as ABCB5 and CD271. Mechanistically, Oct4 induced dedifferentiation was associated with increased expression of endogenous Oct4, Nanog and Klf4, and global gene expression changes that enriched for transcription factors. RNAi mediated knockdown of Oct4 in dedifferentiated cells led to diminished CSC phenotypes. Oct4 expression in melanoma was regulated by hypoxia and its expression was detected in a subpopulation of melanoma cells in clinical samples. Our data indicate that Oct4 is a positive regulator of tumor dedifferentiation. The results suggest that CSC phenotype is dynamic and may be acquired through dedifferentiation. Oct4 mediated tumor cell dedifferentiation may play an important role during tumor progression. PMID:22286766

  15. Overview of recent studies of community-acquired pneumonia.

    Science.gov (United States)

    Higgins, K; Singer, M; Valappil, T; Nambiar, S; Lin, D; Cox, E

    2008-12-01

    All recent studies of antibacterial drugs for the indication of community-acquired pneumonia submitted to the US Food and Drug Administration have been designed as noninferiority studies. We provide a summary of results of 7 recent clinical studies of oral antibacterial drugs for treatment of community-acquired pneumonia. In these 7 studies, the majority of patients enrolled had Pneumonia Patient Outcomes Research Team scores of I or II. The percentage of randomized subjects with pathogens identified at baseline ranged from 47% to 76%, and the percentage of subjects with Streptoccocus pneumoniae isolated at baseline ranged from approximately 6% to 20%. The primary end point in these studies was clinical cure, assessed 7-21 days after completion of therapy. Clinical cure rates were >80% in the intent-to-treat populations and >90% in the per-protocol populations. We also briefly summarize the results from several recently submitted clinical studies of intravenously administered antibacterial drugs for treatment of community-acquired pneumonia, in which we found similar results. PMID:18986282

  16. [National consensus for management of community acquired pneumonia in adults].

    Science.gov (United States)

    Saldías P, Fernando; Pérez C, Carlos

    2005-01-01

    Community acquired pneumonia (CAP) is an acute respiratory infection that affects pulmonary parenchyma, and is caused by community acquired microorganisms. In Chile, pneumonia represents the main cause of death due to infectious diseases and is the third specific cause of mortality in adults. In 1999, an experts committee in representation of "Sociedad Chilena de Enfermedades Respiratorias", presented the first National Guidelines for the Treatment of Adult Community Acquired Pneumonia, mainly based in foreign experience and documents, and adapted it to our National Health System Organization. During the last decade, impressive epidemiological and technological changes have occurred, making the update of guidelines for treatment of NAC by several international scientific societies, necessary. These changes include: new respiratory pathogens that are being identified in CAP and affect adult patients (Mycoplasma pneumoniae, Chlamydia pneumoniae, Legionella pneumophila); the increasing senescent adult population that carries multiple co-morbidities; the emergence of antimicrobial resistance among respiratory pathogens associated to massive antibiotic prescription; the development by the pharmaceutical industry of new drugs that are effective for pneumonia treatment (macrolides, ketolides and respiratory fluorquinolones); and the development of new diagnostic techniques for detection of antigens, antibodies, and bacterial DNA by molecular biology, useful in respiratory infections. Based on these antecedents, an Advisory Committee of "Sociedad Chilena de Enfermedades Respiratorias" and "Sociedad Chilena de Infectología" has reviewed the national and international evidence about CAP management in adults in order to update clinical recommendations for our country.

  17. Transanal approach in repairing acquired rectovestibular fistula in females

    Institute of Scientific and Technical Information of China (English)

    Ya-Jun Chen; Ting-Chong Zhang; Jin-Zhe Zhang

    2004-01-01

    AIM: To summarize the operative experience of the transanal approach in acquired rectovestibular fistula repair.METHODS: Ninety-six cases of acquired rectovestibular fistula in young females were analyzed retrospectively. The etiology and operative procedure were discussed. Operative essential points were, the patient was laid in prone frog position, with the knees and hips flexed at 90°; the perineum was elevated; and the anal opening was exposed. Four stay sutures were applied to the margin of the fistular orifice in the anal opening at points 3, 6, 9 and 12 o'clock.A circular incision of mucosa surrounding the stay sutures was made. The fistula was dissected from its anal opening to its vestibular opening. The wound of vestibule was sutured,and the rectoanal wound was then sutured transversely.RESULTS: All the 96 patients recovered uneventfully from operation with a successful rate of 93.75%.CONCLUSION: The transanal approach in the treatment of the acquired rectovestibular fistula is a simple and feasible technique.

  18. Aesthetics and Composition in Deep Sky Imaging

    Science.gov (United States)

    Gendler, Robert

    It's safe to say that many of us began astrophotography feeling overwhelmed by the unnerving task of creating even the simplest astro image. Typically those first successful images were met with a healthy dose of humility as we began to understand the reality of assembling an aesthetically pleasing astronomical image. As we acquired more experience and gradually mastered the fundamentals of image processing our goals and objectives likely evolved and matured.

  19. Radiographic imaging of aids

    CERN Document Server

    Mahmoud, M B

    2002-01-01

    The acquired immunodeficiency syndrome (AIDS) has impacted the civilized world like no other disease. This research aimed to discuss some of the main aids-related complications and their detection by radiology tests, specifically central nervous system and musculoskeletal system disorders. The objectives are: to show specific characteristics of various diseases of HIV patient, to analyze the effect of pathology in patients by radiology, to enhance the knowledge of technologists in aids imaging and to improve communication skills between patient and radiology technologists.

  20. Simultaneous imaging of MR angiographic image and brain surface image using steady-state free precession

    Energy Technology Data Exchange (ETDEWEB)

    Takane, Atsushi; Tsuda, Munetaka (Hitachi Ltd., Katsuta, Ibaraki (Japan)); Koizumi, Hideaki; Koyama, Susumu; Yoshida, Takeyuki

    1993-09-01

    Synthesis of a brain surface image and an angiographic image representing brain surface vasculatures can be useful for pre-operational contemplation of brain surgery. Both brain surface images and brain surface vasculature images were successfully acquired simultaneously utilizing both FID signals and time-reversed FID signals created under steady-state free precession (SSFP). This simultaneous imaging method has several advantages. No positional discrepancies between both images and prolongation of scan time are anticipated because of concurrent acquisition of the two kinds of image data. Superimposition and stereo-display of both images enable understanding of their spatial relationship, and therefore afford a useful means for pre-operational simulation of brain surgery. (author).

  1. Diffusion tensor imaging of the auditory nerve in patients with acquired single-sided deafness

    DEFF Research Database (Denmark)

    Vos, Sjoerd; Haakma, Wieke; Versnel, Huib;

    2015-01-01

    following cochlear hair cell loss, and the amount of degeneration may considerably differ between the two ears, also in patients with bilateral deafness. A measure that reflects the nerve's condition would help to assess the best of both nerves and decide accordingly which ear should be implanted...... DTI metrics from the deaf-sided with the healthy-sided nerves in patients showed no significant differences. There was a small but significant reduction in fractional anisotropy in both auditory nerves in patients compared with normal-hearing controls. These results are the first evidence of possible...... changes in the microstructure of the bilateral auditory nerves as a result of single-sided deafness. Our results also indicate that it is too early to assess the degenerative status of the auditory nerve of a subject-specific basis....

  2. Vessel segmentation analysis of ischemic stroke images acquired with photoacoustic microscopy

    Science.gov (United States)

    Soetikno, Brian; Hu, Song; Gonzales, Ernie; Zhong, Qiaonan; Maslov, Konstantin; Lee, Jin-Moo; Wang, Lihong V.

    2012-02-01

    We have applied optical-resolution photoacoustic microscopy (OR-PAM) for longitudinal monitoring of cerebral metabolism through the intact skull of mice before, during, and up to 72 hours after a 1-hour transient middle cerebral artery occlusion (tMCAO). The high spatial resolution of OR-PAM enabled us to develop vessel segmentation techniques for segment-wise analysis of cerebrovascular responses.

  3. Series of aerial images over Marais des Cygnes National Wildlife Refuge, acquired February, 1950

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This data set is a georeferenced version of an original black and white aerial photograph downloaded from Earth Explorer (USGS). The original photo was...

  4. Magnetic resonance imaging: early detection of central nervous system involvement in acquired immunodeficiency syndrome (AIDS)

    International Nuclear Information System (INIS)

    Central Nervous System (CNS) involvement, whether primary by the Human Immunodeficiency Virus - HIV - itself, or secondary (toxoplasmosis or lymphoma) is remarkably frequent in AIDS, in 40 to 70% of cases, depending upon the author. In order to study the natural history of this illness, a cohort of 25 asymptomatic seropositive patients have been established. Every 6 months these patients undergo biological and clinical examinations, as well as Magnetic Resonance brain scans. After two examinations at a 6 month's interval, the first results are reported. Out of these 25 cases, 9 present anomalies: One patient with diffuse cerebral atrophy and 8 others with high signal intensity areas on T2 weighted sequences, like those of the Multiple Sclerosis. No relationship could be demonstrated between the existence of these lesions and various criteria such as age, sex, risk factors and T4 cells count. The nature of these lesions is not lear. They certainly indicate early involvement of the CNS after primary infection by the HIV virus. They may either represent scars of the primary infection or early alterations announcing developing encephalopathy

  5. Can Colors, Voices, and Images Help Learners Acquire the Grammatical Gender of German Nouns?

    Science.gov (United States)

    Dias de Oliveira Santos, Victor

    2015-01-01

    Knowledge of lexical items is arguably the most essential aspect of being able to communicate in a foreign language (Richards, 2000). Many studies have examined effective strategies for retaining the meaning of foreign words, but studies investigating the effectiveness of different methods for the retention of essential grammatical features of…

  6. Series of aerial images over Monte Vista National Wildlife Refuge, acquired September 8, 1985

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This data set includes two georeferenced versions of color aerial photographs from September 8, 1985, taken over Monte Vista National Wildlife Refuge. A...

  7. Series of aerial images over Monte Vista National Wildlife Refuge, acquired July 13th, 1965

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This data set includes 31 georeferenced versions of black and white aerial photographs from July 13th, 1965, taken over Monte Vista National Wildlife Refuge. A...

  8. Series of aerial images over Baca National Wildlife Refuge, acquired July, 1988

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This data set includes 21 georeferenced and clipped versions of aerial photographs from July 22nd, 1988, taken over Baca National Wildlife Refuge. A georeferenced...

  9. Series of aerial images over Alamosa National Wildlife Refuge, acquired in 1953

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This data set includes 16 georeferenced and clipped versions of aerial photographs from September 29th and October 1st, 1953, taken over Alamosa National Wildlife...

  10. Series of aerial images over Monte Vista National Wildlife Refuge, acquired in 1960

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This data set includes 7 georeferenced and clipped versions of aerial photographs from August 1960, taken over Monte Vista National Wildlife Refuge. A georeferenced...

  11. Series of aerial images over Alamosa National Wildlife Refuge, acquired July, 1988

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This data set includes seven georeferenced and clipped versions of aerial photographs from July 22nd, 1988, taken over Alamosa National Wildlife Refuge. A...

  12. Series of aerial images over Monte Vista National Wildlife Refuge, acquired August 26th, 1989

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This data set includes five georeferenced versions of color aerial photographs from August 26th, 1989, taken over Monte Vista National Wildlife Refuge. Like other...

  13. Aerial Image over Ouray National Wildlife Refuge, Acquired on September 4, 1963 (Frame 121)

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This data set is a georeferenced version of an original black and white aerial photograph downloaded from Earth Explorer (USGS; www.earthexplorer.usgs.gov). The...

  14. Aerial Image over Ouray National Wildlife Refuge, Acquired on September 4, 1963 (Frame 135)

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This data set is a georeferenced version of an original black and white aerial photograph downloaded from Earth Explorer (USGS; www.earthexplorer.usgs.gov). The...

  15. Aerial Image over Ouray National Wildlife Refuge, Acquired on September 4, 1963 (Frame 88)

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This data set is a georeferenced version of an original black and white aerial photograph downloaded from Earth Explorer (USGS; www.earthexplorer.usgs.gov). The...

  16. Aerial Image over Ouray National Wildlife Refuge, Acquired on August 11, 1953

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This data set is a georeferenced version of an original black and white aerial photograph downloaded from Earth Explorer (USGS; www.earthexplorer.usgs.gov). The...

  17. Aerial Image over Ouray National Wildlife Refuge, Acquired on September 4, 1963 (Frame 134)

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This data set is a georeferenced version of an original black and white aerial photograph downloaded from Earth Explorer (USGS; www.earthexplorer.usgs.gov). The...

  18. Estimating plant traits of grasslands from UAV-acquired hyperspectral images

    NARCIS (Netherlands)

    Capolupo, Alessandra; Kooistra, Lammert; Berendonk, Clara; Boccia, Lorenzo; Suomalainen, Juha

    2015-01-01

    Grassland ecosystems cover around 40% of the entire Earth's surface. Therefore, it is necessary to guarantee good grassland management at field scale in order to improve its conservation and to achieve optimal growth. This study identified the most appropriate statistical strategy, between partia

  19. Community-acquired pneumonia in older patients: does age influence systemic cytokine levels in community-acquired pneumonia?

    LENUS (Irish Health Repository)

    Kelly, Emer

    2009-03-01

    Community-acquired pneumonia (CAP) is a major cause of death in the elderly. The age-related increase in comorbid illnesses plays a part but the effect of aging on the immune response may be equally important. We aimed to evaluate patients with CAP for evidence of a muted response to infection in elderly patients admitted to hospital compared with a younger patient group.

  20. Turbine Imaging Technology Assessment

    Energy Technology Data Exchange (ETDEWEB)

    Moursund, Russell A.; Carlson, Thomas J.

    2004-12-31

    The goal of this project was to identify and evaluate imaging alternatives for observing the behavior of juvenile fish within an operating Kaplan turbine unit with a focus on methods to quantify fish injury mechanisms inside an operating turbine unit. Imaging methods are particularly needed to observe the approach and interaction of fish with turbine structural elements. This evaluation documents both the opportunities and constraints for observing juvenile fish at specific locations during turbine passage. The information may be used to acquire the scientific knowledge to make structural improvements and create opportunities for industry to modify turbines and improve fish passage conditions.

  1. NMR imaging technique

    International Nuclear Information System (INIS)

    This invention provides a method that can be adapted to existing NMR tomographic scanners of producing spectra of any given point in the image of the specimen slice, the intensity distribution of a selected resonance within an area of the image of the specimen slice, or an entire NMR spectrum of the given area. The method comprises acquiring n projections of the specimen slice, where n is greater than 1. Each of the projections is then shifted by Δ f for the point (the frequency offset of the signal arising from the point, from the true chemical shift)

  2. Derivative encoding for parallel magnetic resonance imaging a

    OpenAIRE

    Shen, Jun

    2011-01-01

    Purpose: To introduce a linear shift-invariant relationship between the partial derivatives of k space signals acquired using multichannel receive coils and to demonstrate that k space derivatives can be used for image unwrapping.Methods: Fourier transform of k space derivatives contains information on the spatial origins of aliased pixels; therefore, images can be reconstructed by k space derivatives. Fully sampled phantom and brain images acquired at 3 T using a standard eight channel recei...

  3. The portal vein in children: radiological review of congenital anomalies and acquired abnormalities

    Energy Technology Data Exchange (ETDEWEB)

    Corness, Jonathan A.G.; McHugh, Kieran; Roebuck, Derek J. [Great Ormond Street Hospital for Children, Department of Radiology, London (United Kingdom); Taylor, Andrew M. [Institute of Child Health, Cardiothoracic Unit, London (United Kingdom)

    2006-02-01

    A variety of portal vein anomalies that occur in children can be identified by US, CT, MRI and portal venography. Although these abnormalities can also occur in adults, there are certain pathological processes and aberrations within the portal system that are specific to children. Knowledge of the embryology and anatomy of the portal vein is of benefit in the understanding of these anomalies. Identifying deviations from normal portal architecture is important in the work-up for surgery such as liver transplantation, and prior to interventional procedures such as stent placement or embolization. The aim of this paper is to summarize the various types of congenital and acquired portal vein abnormalities that occur in children, describe their radiological features and provide images to demonstrate the differences from normal portal venous anatomy. (orig.)

  4. Toxoplasmosis of spinal cord in acquired immunodeficiency syndrome patient presenting as paraparesis: A rare entity

    Directory of Open Access Journals (Sweden)

    Sachin R Agrawal

    2014-01-01

    Full Text Available Although brain has been the most common site for toxoplasma infection in acquired immunodeficiency syndrome patients, involvement of spinal cord by toxoplasma has been rarely found. Spinal cord toxoplasmosis can present as acute onset weakness in both lower limbs associated with sensory and bladder dysfunction. A presumptive diagnosis can be made in patients with CD4 count <100/mm 3 based on a positive serum Toxoplasma gondii IgG antibodies, no recent prophylaxis against toxoplasmosis, intramedullary ring enhancing lesion in spinal cord supported by similar lesions in brain parenchyma. Institutions of antitoxoplasma treatment in such patients result in prompt clinical response and therefore avoiding the need of unnecessary invasive diagnostic tests. Here, we report a case of toxoplasmic myelitis in immunocompromised patient presenting as myelopathy who showed significant clinical improvement after starting antitoxoplasma treatment. Hence toxoplasmic myelitis should be considered in toxoplasma seropositive immunocompromised patients presenting as myelopathy and imaging studies showing ring enhancing intramedullary lesion.

  5. Image Degradation in Microscopic Images: Avoidance, Artifacts, and Solutions.

    Science.gov (United States)

    Roels, Joris; Aelterman, Jan; De Vylder, Jonas; Lippens, Saskia; Luong, Hiêp Q; Guérin, Christopher J; Philips, Wilfried

    2016-01-01

    The goal of modern microscopy is to acquire high-quality image based data sets. A typical microscopy workflow is set up in order to address a specific biological question and involves different steps. The first step is to precisely define the biological question, in order to properly come to an experimental design for sample preparation and image acquisition. A better object representation allows biological users to draw more reliable scientific conclusions. Image restoration can manipulate the acquired data in an effort to reduce the impact of artifacts (spurious results) due to physical and technical limitations, resulting in a better representation of the object of interest. However, precise usage of these algorithms is necessary so as to avoid further artifacts that might influence the data analysis and bias the conclusions. It is essential to understand image acquisition, and how it introduces artifacts and degradations in the acquired data, so that their effects on subsequent analysis can be minimized. This paper provides an overview of the fundamental artifacts and degradations that affect many micrographs. We describe why artifacts appear, in what sense they impact overall image quality, and how to mitigate them by first improving the acquisition parameters and then applying proper image restoration techniques.

  6. Illumination Correction on Biomedical Images

    OpenAIRE

    Edoardo Ardizzone; Roberto Pirrone; Orazio Gambino; Salvatore Vitabile

    2014-01-01

    RF-Inhomogeneity Correction (aka bias) artifact is an important research field in Magnetic Resonance Imaging (MRI). Bias corrupts MR images altering their illumination even though they are acquired with the most recent scanners. Homomorphic Unsharp Masking (HUM) is a filtering technique aimed at correcting illumination inhomogeneity, but it produces a halo around the edges as a side effect. In this paper a novel correction scheme based on HUM is proposed to correct the artifact mentioned abov...

  7. Optimal management of common acquired melanocytic nevi (moles: current perspectives

    Directory of Open Access Journals (Sweden)

    Sardana K

    2014-03-01

    Full Text Available Kabir Sardana, Payal Chakravarty, Khushbu Goel Department of Dermatology and STD, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, Delhi, India Abstract: Although common acquired melanocytic nevi are largely benign, they are probably one of the most common indications for cosmetic surgery encountered by dermatologists. With recent advances, noninvasive tools can largely determine the potential for malignancy, although they cannot supplant histology. Although surgical shave excision with its myriad modifications has been in vogue for decades, the lack of an adequate histological sample, the largely blind nature of the procedure, and the possibility of recurrence are persisting issues. Pigment-specific lasers were initially used in the Q-switched mode, which was based on the thermal relaxation time of the melanocyte (size 7 µm; 1 µsec, which is not the primary target in melanocytic nevus. The cluster of nevus cells (100 µm probably lends itself to treatment with a millisecond laser rather than a nanosecond laser. Thus, normal mode pigment-specific lasers and pulsed ablative lasers (CO2/erbium [Er]:yttrium aluminum garnet [YAG] are more suited to treat acquired melanocytic nevi. The complexities of treating this disorder can be overcome by following a structured approach by using lasers that achieve the appropriate depth to treat the three subtypes of nevi: junctional, compound, and dermal. Thus, junctional nevi respond to Q-switched/normal mode pigment lasers, where for the compound and dermal nevi, pulsed ablative laser (CO2/Er:YAG may be needed. If surgical excision is employed, a wide margin and proper depth must be ensured, which is skill dependent. A lifelong follow-up for recurrence and melanoma is warranted in predisposed individuals, although melanoma is decidedly uncommon in most acquired melanocytic nevi, even though histological markers may be seen on evaluation. Keywords: lasers, surgery, nevus, melanoma

  8. Community acquired urinary tract infection: etiology and bacterial susceptibility

    Directory of Open Access Journals (Sweden)

    Dias Neto José Anastácio

    2003-01-01

    Full Text Available PURPOSE: Urinary tract infections (UTI are one of the most common infectious diseases diagnosed. UTI account for a large proportion of antibacterial drug consumption and have large socio-economic impacts. Since the majority of the treatments begins or is done completely empirically, the knowledge of the organisms, their epidemiological characteristics and their antibacterial susceptibility that may vary with time is mandatory. OBJECTIVE: The aim of this study was to report the prevalence of uropathogens and their antibiotic susceptibility of the community acquired UTI diagnosed in our institution and to provide a national data. METHODS: We analyzed retrospectively the results of urine cultures of 402 patients that had community acquired urinary tract infection in the year of 2003. RESULTS: The mean age of the patients in this study was 45.34 ± 23.56 (SD years. There were 242 (60.2% females and 160 (39.8% males. The most commonly isolated organism was Escherichia coli (58%. Klebsiella sp. (8.4% and Enterococcus sp.(7.9% were reported as the next most common organisms. Of all bacteria isolated from community acquired UTI, only 37% were sensitive to ampicillin, 51% to cefalothin and 52% to trimethoprim/sulfamethoxazole. The highest levels of susceptibility were to imipenem (96%, ceftriaxone (90%, amikacin (90%, gentamicin (88%, levofloxacin (86%, ciprofloxacin (73%, nitrofurantoin (77% and norfloxacin (75%. CONCLUSION: Gram-negative agents are the most common cause of UTI. Fluoroquinolones remains the choice among the orally administered antibiotics, followed by nitrofurantoin, second and third generation cephalosporins. For severe disease that require parenteral antibiotics the choice should be aminoglycosides, third generation cephalosporins, fluoroquinolones or imipenem, which were the most effective.

  9. Severe peritonitis due to Balantidium coli acquired in France.

    Science.gov (United States)

    Ferry, T; Bouhour, D; De Monbrison, F; Laurent, F; Dumouchel-Champagne, H; Picot, S; Piens, M A; Granier, P

    2004-05-01

    The case reported here concerns an alcoholic pork-butcher who presented with severe colitis with peritonitis, caused by the only ciliate protozoan capable of infecting humans, Balantidium coli. This parasite is common in a variety of domestic and wild mammals, mainly pigs; however, its prevalence rate in humans is very low--particularly in industrialised, northern countries, including France. The infection is most frequently acquired by ingesting food or water contaminated by pig faeces, and it may be asymptomatic or may cause acute diarrhoea. Specific antibiotic treatment is efficacious, and it is important to consider the risk of this parasitic disease in susceptible patients presenting with bloody diarrhoea. PMID:15112068

  10. Office-based management of adult-acquired flatfoot deformity.

    Science.gov (United States)

    Miniaci-Coxhead, Sara Lyn; Flemister, Adolph Samuel

    2014-03-01

    Adult-acquired flatfoot deformity is associated with dysfunction of the posterior tibial tendon, leading to loss of the medial arch. Patients tend to present with medial pain and swelling, but later in the disease process can also present with lateral-sided pain. The mainstay of nonoperative treatment is nonsteroidal anti-inflammatory drugs, weight loss, and orthotic insoles or brace use. The goals of therapy are to provide relief of symptoms and prevent progression of the deformity. If nonoperative management fails, a variety of surgical procedures are available; however, these require a lengthy recovery, and therefore patients should be advised accordingly.

  11. [Epidemiology of community-acquired pneumonia in children. Current data].

    Science.gov (United States)

    Marguet, C; Bocquel, N; Mallet, E

    1998-01-01

    Viruses, particularly syncitial respiratory virus, are the main aetiology of community-acquired lower respiratory tract infections in infants, while bacterial agents are more frequently responsible in children older than 3 years. Antimicrobial therapy must take into account the development of reduced susceptibility of penicillin to strains of Streptoccocus pneumoniae and Haemophilus influenzae with beta-lactamase, and high frequency of Mycoplasma pneumoniae and Chlamydia pneumoniae infections. Although the mortality rate has remained low in France, the morbidity appeared to increase in recent years. PMID:10223154

  12. Polymicrobial community-acquired pneumonia: An emerging entity.

    Science.gov (United States)

    Cillóniz, Catia; Civljak, Rok; Nicolini, Antonello; Torres, Antoni

    2016-01-01

    Polymicrobial aetiology in community-acquired pneumonia (CAP) is more common than previously recognized. This growing new entity can influence inflammation, host immunity and disease outcomes in CAP patients. However, the true incidence is complicated to determine and probably underestimated due mainly to many cases going undetected, particularly in the outpatient setting, as the diagnostic yield is restricted by the sensitivity of currently available microbiologic tests and the ability to get certain types of clinical specimens. The observed rate of polymicrobial cases may also lead to new antibiotic therapy considerations. In this review, we discuss the pathogenesis, microbial interactions in pneumonia, epidemiology, biomarkers and antibiotic therapy for polymicrobial CAP.

  13. Gesture Based Educational Software for Children with Acquired Brain Injuries

    Directory of Open Access Journals (Sweden)

    Er. Zainab Pirani

    2010-05-01

    Full Text Available " GESBI” is gesture based audio visual teaching tool designed to help children with acquired brain injuries, providing hours of entertainment in a play-and-learn environment while introducing the foundation skills in basic arithmetic, spelling, reading and solving puzzles. These children communicate with the computer via gestures based on my previous research paper “KONCERN- Hand Gesture Recognition for Physically Impaired” in which gestures are captured by camera and processed without the need of wearing any sensor based gloves etc.

  14. Integrating New Technical Staff: Implications for Acquiring New Technology

    OpenAIRE

    Lee, Denis M. S.; Allen, Thomas J. (Thomas John), 1931-

    1982-01-01

    Hiring new staff in R&D provides an important opportunity for a firm to acquire new technological knowledge. It also takes a considerable length of time before new R&D staff become fully integrated into the organization. This study compares the communication patterns of new and veteran R&D staff as a function of their work activities. The results suggest that both the benefits and problems in the hiring and integration of new R&D staff is moderated by the type of research, development or tech...

  15. Community-Acquired urinary tract infection by pseudomonas oryzihabitans

    Directory of Open Access Journals (Sweden)

    Sunita M Bhatawadekar

    2013-01-01

    Full Text Available Pseudomonas oryzihabitans and Chrysomonas luteola has been placed in CDC group Ve2 and Ve1 respectively. These bacteria appear to be emerging pathogens. P. oryzihabitans was isolated from cases of bacteremia, CNS infections, wound infections, peritonitis, sinusitis, catheter associated infections in AIDS patient, and pneumonia. Most of the reports of P. oryzihabitans infection were of nosocomial origin in individuals with some predisposing factors. We report here a case of community acquired UTI by P. oryzihabitans in an immune-competent patient with stricture of urethra.

  16. Acquired Lymphangioma Circumscriptum Caused Macroglossia: A Case Report

    Directory of Open Access Journals (Sweden)

    Mahmut Sami Metin

    2015-03-01

    Full Text Available Lymphangioma circumscriptum (LC is a hamartomatous vascular malformation of lymphatic channels. The etiology is not fully understood. It is usually congenital. Lesions are characterized as thin-walled and grouped vesicles. Lesions are usually seen on proximal extremities, shoulder, axilla, abdomen and neck. They are rarely seen on genital and oral mucosa. Our case was 20 years old male suffering from growing, pain and burning of tongue for 2 months durations. There was a plaque consisted of grouped vesicles on tongue in dermatological examination. Biopsy was obtained. LC was diagnosed. We decided to report this case since acquired LC on tongue and macroglossi is very rare in literature.

  17. Approach and treatment of the adult acquired flatfoot deformity.

    Science.gov (United States)

    Vulcano, Ettore; Deland, Jonathan T; Ellis, Scott J

    2013-12-01

    Adult acquired flatfoot deformity (AAFD), embraces a wide spectrum of deformities. AAFD is a complex pathology consisting both of posterior tibial tendon insufficiency and failure of the capsular and ligamentous structures of the foot. Each patient presents with characteristic deformities across the involved joints, requiring individualized treatment. Early stages may respond well to aggressive conservative management, yet more severe AAFD necessitates prompt surgical therapy to halt the progression of the disease to stages requiring more complex procedures. We present the most current diagnostic and therapeutic approaches to AAFD, based on the most pertinent literature and our own experience and investigations. PMID:23765382

  18. Acquired lymphangiectasis following surgery and radiotherapy of breast cancer

    Directory of Open Access Journals (Sweden)

    Angoori Gnaneshwar Rao

    2015-01-01

    Full Text Available Acquired lymphangiectasia (AL is a significant and rare complication of surgery and radiotherapy. We report lymphangiectasia in a 40-year-old woman who had undergone radical mastectomy and radiotherapy. After 4 years of combined therapy, she developed multiple vesicles and bullae. Skin biopsy confirmed the diagnosis of lymphangiectasia. The case is unique as it is not associated with lymphedema, which is a usual accompaniment of lymphangiectasia following surgery and radiotherapy. AL is usually asymptomatic, but trauma may cause recurrent cellulitis. Treatment modalities include electrodessication, surgical excision, sclerotherapy and carbon dioxide laser ablation.

  19. Summary Statistics for Fun Dough Data Acquired at LLNL

    Energy Technology Data Exchange (ETDEWEB)

    Kallman, J S; Morales, K E; Whipple, R E; Huber, R D; Brown, W D; Smith, J A; Schneberk, D J; Martz, Jr., H E; White, III, W T

    2010-03-11

    Using x-ray computerized tomography (CT), we have characterized the x-ray linear attenuation coefficients (LAC) of a Play Dough{trademark}-like product, Fun Dough{trademark}, designated as PD. Table 1 gives the first-order statistics for each of four CT measurements, estimated with a Gaussian kernel density estimator (KDE) analysis. The mean values of the LAC range from a high of about 2100 LMHU{sub D} at 100kVp to a low of about 1100 LMHU{sub D} at 300kVp. The standard deviation of each measurement is around 1% of the mean. The entropy covers the range from 3.9 to 4.6. Ordinarily, we would model the LAC of the material and compare the modeled values to the measured values. In this case, however, we did not have the composition of the material and therefore did not model the LAC. Using a method recently proposed by Lawrence Livermore National Laboratory (LLNL), we estimate the value of the effective atomic number, Z{sub eff}, to be near 8.5. LLNL prepared about 50mL of the Fun Dough{trademark} in a polypropylene vial and firmly compressed it immediately prior to the x-ray measurements. Still, layers can plainly be seen in the reconstructed images, indicating that the bulk density of the material in the container is affected by voids and bubbles. We used the computer program IMGREC to reconstruct the CT images. The values of the key parameters used in the data capture and image reconstruction are given in this report. Additional details may be found in the experimental SOP and a separate document. To characterize the statistical distribution of LAC values in each CT image, we first isolated an 80% central-core segment of volume elements ('voxels') lying completely within the specimen, away from the walls of the polypropylene vial. All of the voxels within this central core, including those comprised of voids and inclusions, are included in the statistics. We then calculated the mean value, standard deviation and entropy for (a) the four image segments and

  20. Aerial Image Series Quality Assessment

    International Nuclear Information System (INIS)

    With the growing demand for geospatial data, the aerial imagery with high spatial, spectral, and temporal resolution achieves great development. It is imperative to evaluate whether the acquired images are qualified enough, since the further image mosaic asks for strict time consistency and a re-flight involves considerable resources. In this paper, we address the problem of quick aerial image series quality assessment. An image series quality analysis system is proposed, which includes single image quality assessment, image series quality assessment based on the image matching, and offering a visual matching result in real time for human validation when the computer achieves dubious results. For two images, the affine matrix is different for different parts of images, especially for images of wide field. Therefore we calculate transfer matrixes by using even-distributed control points from different image parts with the RANSAC technology, and use the image rotation angle for image mosaic for human validation. Extensive experiments conducted on aerial images show that the proposed method can obtain similar results with experts

  1. Assessment of scintigraphic image quality in Single Photon Emission Computed Tomography (SPECT) using jaszczak phantom

    International Nuclear Information System (INIS)

    The image quality of scintigraphic images has been improved by applying a MatLab algorithm code and five different filters to an acquired image of the data spectrum (Jaszczak) phantom and the FWHM (resolution) values measured using ImageJ software. The average FWHM value recorded for the acquired image and the Matlab enhanced image were 14.246±0.205 mm and 11.609±1.458 mm respectively. The analyses performed on the acquired image showed improvements in its resolution. Combination of the MatLab algorithm code and the Trous-Wavelet filter gave the best improvement in resolution of the acquired image, with an average FWHM value of 10.261±1.381 mm. This indicates a 27.973% improvement in the FWHM value of the acquired image. The CLAHE filter, Kuwahara filter, Sigma filter Plus and filter rank, improved the resolution of the acquired image by 21.627%, 17.48%, 4.745% and 8.949% respectively. Results from the study indicate that the acquired image was improved in quality by applying the Matlab image enhancement tool and filters. The outcome of this study shows promise in aiding nuclear medicine physicians to make improved diagnostic decisions if applied to clinical cases.(au)

  2. Summary Statistics for Homemade ?Play Dough? -- Data Acquired at LLNL

    Energy Technology Data Exchange (ETDEWEB)

    Kallman, J S; Morales, K E; Whipple, R E; Huber, R D; Martz, A; Brown, W D; Smith, J A; Schneberk, D J; Martz, Jr., H E; White, III, W T

    2010-03-11

    Using x-ray computerized tomography (CT), we have characterized the x-ray linear attenuation coefficients (LAC) of a homemade Play Dough{trademark}-like material, designated as PDA. Table 1 gives the first-order statistics for each of four CT measurements, estimated with a Gaussian kernel density estimator (KDE) analysis. The mean values of the LAC range from a high of about 2700 LMHU{sub D} 100kVp to a low of about 1200 LMHUD at 300kVp. The standard deviation of each measurement is around 10% to 15% of the mean. The entropy covers the range from 6.0 to 7.4. Ordinarily, we would model the LAC of the material and compare the modeled values to the measured values. In this case, however, we did not have the detailed chemical composition of the material and therefore did not model the LAC. Using a method recently proposed by Lawrence Livermore National Laboratory (LLNL), we estimate the value of the effective atomic number, Z{sub eff}, to be near 10. LLNL prepared about 50mL of the homemade 'Play Dough' in a polypropylene vial and firmly compressed it immediately prior to the x-ray measurements. We used the computer program IMGREC to reconstruct the CT images. The values of the key parameters used in the data capture and image reconstruction are given in this report. Additional details may be found in the experimental SOP and a separate document. To characterize the statistical distribution of LAC values in each CT image, we first isolated an 80% central-core segment of volume elements ('voxels') lying completely within the specimen, away from the walls of the polypropylene vial. All of the voxels within this central core, including those comprised of voids and inclusions, are included in the statistics. We then calculated the mean value, standard deviation and entropy for (a) the four image segments and for (b) their digital gradient images. (A digital gradient image of a given image was obtained by taking the absolute value of the difference

  3. Cancer resistance as an acquired and inheritable trait

    DEFF Research Database (Denmark)

    Koch, Janne; Hau, Jann; Jensen, Henrik Elvang;

    2014-01-01

    AIM: To induce cancer resistance in wild-type mice and detect if the resistance could be inherited to the progeny of the induced resistant mice. Furthermore to investigate the spectrum and immunology of this inherited cancer resistance. MATERIALS AND METHODS: Resistance to with live S180 cancer c...... of the resistance is unknown but may involve epigenetic mechanisms. Other examples of inheritability of acquired phenotypic changes exist but, to our knowledge, this is the first demonstration of acquired, inherited cancer resistance.......AIM: To induce cancer resistance in wild-type mice and detect if the resistance could be inherited to the progeny of the induced resistant mice. Furthermore to investigate the spectrum and immunology of this inherited cancer resistance. MATERIALS AND METHODS: Resistance to with live S180 cancer...... cells in BALB/c mice was induced by immunization with inactivated S180 cancer cells. The immunization was performed by either frozen/thawed or irradiated cancer cells or cell-free ascitic fluid (CFAF). RESULTS: In all instances the induced resistance was demonstrated to be inheritable. The phenotype...

  4. Paragonimiasis acquired in the United States: native and nonnative species.

    Science.gov (United States)

    Diaz, James H

    2013-07-01

    Paragonimiasis is a parasitic lung infection caused by lung flukes of the genus Paragonimus, with most cases reported from Asia and caused by P. westermani following consumption of raw or undercooked crustaceans. With the exception of imported P. westermani cases in immigrants, in travelers returning from areas of disease endemicity, and in clusters of acquired cases following consumption of imported Asian crabs, human paragonimiasis caused by native lung flukes is rarely described in the United States, which has only one indigenous species of lung fluke, Paragonimus kellicotti. Clinicians should inquire about the consumption of raw or undercooked freshwater crabs by immigrants, expatriates, and returning travelers, and the consumption of raw or undercooked crayfish in U.S. freshwater river systems where P. kellicotti is endemic when evaluating patients presenting with unexplained fever, cough, rales, hemoptysis, pleural effusions, and peripheral eosinophilia. Diagnostic evaluation by specific parasitological, radiological, serological, and molecular methods will be required in order to differentiate paragonimiasis from tuberculosis, which is not uncommon in recent Asian immigrants. All cases of imported and locally acquired paragonimiasis will require treatment with oral praziquantel to avoid any potential pulmonary and cerebral complications of paragonimiasis, some of which may require surgical interventions.

  5. SUMMARY OF LONG TERM EXPERIENCE IN ACQUIRED HEART DISEASES SURGERY

    Directory of Open Access Journals (Sweden)

    M. L. Semenovsky

    2014-01-01

    Full Text Available In this article we discuss the results of surgical treatment in patients with different acquired heart diseases. Procedures ranged from valve reconstruction, coronary artery revascularization, surgical repair or graft repair of the thoracic aorta to hybrid surgery in patients with combined acquired heart valve diseases and coronary artery diseases. The implementation of biological grafts for aortic repair in 147 cases was successfully performed with low in-hospital mortality (9.8%. Hybrid procedures in patients older than 70 years allowed reducing hospital mortality rate in 3 times in comparison with the standard surgery: 4% vs. 12%, respectively. We developed and introduced into clinical practice the original protocol for patients with aortal valve disease and low left ventricularejection fraction (mean – 24.3%. Due to this protocol 46 procedures were performed, in-hospital mortality was 4.4%. Cardiac surgery in patients on dialysis is one of the priorities in our practice. Our experience demonstrates that short waiting time of kidney transplantation after heart valve replacement improves long-term outcomes.

  6. Is it Difficult to Acquire Subjacency and the ECP

    Directory of Open Access Journals (Sweden)

    Chun-yin Doris Chen

    2006-06-01

    Full Text Available This paper aims to examine English- and Japanese-speaking adult learners’ acquisition of Subjacency and the Empty Category Principle (ECP (Chomsky 1981, 1986 in Chinese. The participants were forty intermediate foreign students of the Mandarin Training Center of Nation Taiwan Normal University: half were native English speakers and half Japanese. In addition, there were twenty native controls. Two tasks (i.e., a preference task and an ordering task were designed on the basis of the following properties concerning Subjacency and the ECP: wh-island constraints, complex NP constraints, sentential subject constraints, that-trace effects and subject/object asymmetries, and superiority L2 learners carried their L1 knowledge to acquire Subjacency and the ECP, suggesting the L1 influence is not significant. Furthermore, it was found that the Japanese speakers did not perform significantly better than the English speakers. This shows that Universal Grammar is still available, since our participants have reset their L1 parameters to proper L2 values. In addition, among these features our participants did less well on non-superiority, and the native controls rejected island violations more strongly than either group of L2 participants. Finally, Subjacency and the ECP were found equally easy for our participants to acquire.

  7. Acquired Multiple Cysts of the Kidney in Neuroblastoma Survivors.

    Science.gov (United States)

    Moodalbail, Divya G; Apple, Leah Z; Meyers, Kevin E; Ginsberg, Jill P; Kaplan, Bernard S; Bellah, Richard

    2016-07-01

    Cystic kidney disease includes a wide range of hereditary, developmental, and acquired conditions of the kidneys. Some of the inherited causes of cystic kidney disease include autosomal dominant polycystic kidney diseases (caused by mutations in PKD1 or PKD2), autosomal recessive polycystic kidney disease, tuberous sclerosis complex, von Hippel-Lindau disease, oral-facial-digital syndrome type I, and Hadju-Cheney syndrome. Acquired cystic kidney disease has been reported in patients receiving long-term hemodialysis or peritoneal dialysis and in children after liver transplantation. Acute kidney injury can occur in patients with neuroblastoma, usually as a result of thrombotic microangiopathy associated with bone marrow transplantation. End-stage renal disease is described in long-term survivors. However, in this case report, we provide what is to our knowledge the first description of multiple kidney cysts in long-term survivors of stage IV neuroblastoma. None of the 7 patients we describe with neuroblastoma and multiple kidney cysts had a family history of autosomal dominant polycystic kidney disease. Also, all lacked stigmata of tuberous sclerosis complex, von Hippel-Lindau disease, or Hadju-Cheney syndrome. Two patients progressed to end-stage renal disease; in addition, one of them developed an oncocytoid renal cell carcinoma. PMID:27016049

  8. Analysis of clinical manifestations of symptomatic acquired jejunoileal diverticular disease

    Institute of Scientific and Technical Information of China (English)

    Chia-Yuan Liu; Wen-Hsiung Chang; Shee-Chan Lin; Cheng-Hsin Chu; Tsang-En Wang; Shou-Chuan Shih

    2005-01-01

    AIM: To analyze systematically our experience over 22 years with symptomatic acquired diverticular disease of the jejunum and ileum, exploring the clinical manifestations and diagnosis of this rare but life-threatening disease.METHODS: The medical records of patients with surgically confirmed symptomatic jejunoileal diverticular disease were retrospectively reviewed. Data collected included demographic data, laboratory results, clinical course (acute or chronic), preoperative diagnosis, and operative findings. Inclusion criteria were as follows: (1) surgical confirmation of jejunoileal diverticular disease and (2)exclusion of congenital diverticula (e.g. Meckel's diverticulum).RESULTS: From January 1982 to July 2004, 28 patients with a total of 29 operations met the study criteria. The male:female ratio was 14:14, and the mean age was 62.6±3.5 years. The most common manifestation was abdominal pain. In nearly half of the patients, the symptoms were chronic. Two patients died after surgery. Only four cases were correctly diagnosed prior to surgery, three by small bowel series.CONCLUSION: Symptomatic acquired small bowel diverticular disease is difficult to diagnose. It should be considered in older patients with unexplained chronic abdominal symptoms. A small bowel series may be helpful in diagnosing this potentially life-threatening disease.

  9. Prevalence and bacterial susceptibility of hospital acquired urinary tract infection

    Directory of Open Access Journals (Sweden)

    Dias Neto José Anastácio

    2003-01-01

    Full Text Available PURPOSE: Urinary tract infection is the most common nosocomially acquired infection. It is important to know the etiology and antibiotic susceptibility infectious agents to guide the initial empirical treatment. OBJECTIVE: To determine the prevalence of bacterial strains and their antibiotic susceptibility in nosocomially acquired urinary tract infection in a university hospital between January and June 2003. METHODS: We analyzed the data of 188 patients with positive urine culture (= 10(5 colony-forming units/mL following a period of 48 hours after admission. RESULTS: Half of patients were male. Mean age was 50.26 ± 22.7 (SD, range 3 months to 88 years. Gram-negative bacteria were the agent in approximately 80% of cases. The most common pathogens were E. coli (26%, Klebsiella sp. (15%, P. aeruginosa (15% and Enterococcus sp. (11%. The overall bacteria susceptibility showed that the pathogens were more sensible to imipenem (83%, second or third generation cephalosporin and aminoglycosides; and were highly resistant to ampicillin (27% and cefalothin (30%. It is important to note the low susceptibility to ciprofloxacin (42% and norfloxacin (43%. CONCLUSION: This study suggests that if one can not wait the results of urine culture, the best choices to begin empiric treatment are imipenem, second or third generation cephalosporin and aminoglycosides. Cefalothin and ampicillin are quite ineffective to treat these infections.

  10. [ANEMIC SYNDROME IN PATIENTS WITH COMMUNITY-ACQUIRED PNEUMONIA].

    Science.gov (United States)

    Budnevsky, A V; Esaulenko, I E; Ovsyannikov, E S; Labzhaniya, N B; Voronina, E V; Chernov, A V

    2016-01-01

    Community-acquired pneumonia remains a most widespread acute infectious disease of socio-economic significance all over the world. Up to 30% of the patients present with anemia responsible for the unfavourable prognosis and elevated mortality. Not infrequently, anemia is not diagnosed during the hospital stay und therefore remains uncorrected. Severe anemia results in enhanced hypercapnia and slowed maturation of red blood cells in the bone marrow which facilitates the development of ischemic syndrome. Hepcidin, a mediator of inflammation and iron-regulatory hormone, plays an important role in the clinical course of community-acquired pneumonia. Hepsidin production increases during inflammation; it suppresses erythtropoiesis and depletes the iron depot leading to so-called anemia of inflammation. Hypoxia and anemia activate erythtropoiesis, and the released erythropoietin inhibits hepsidin production. During pneumonia resolution, hepsidin promotes recovery from anemia by activating iron absorption. The curreni literature contains few data on the use of hepcidin as a diagnostic marker of anemia. The necessity oftreating anemia in patients with pneumonia under hospital conditions is a matter of discussion. Direct involvement of hepcidin in iron metabolism creates a prerequisite for the treatment of anemia. Medicamental suppression of its activity by stimulating erythtropoiesis can facilitate normalization of iron metabolism and restoration of hemoglobin level.

  11. A review of current progress in acquired cholesteatoma management.

    Science.gov (United States)

    Kuo, Chin-Lung; Liao, Wen-Huei; Shiao, An-Suey

    2015-12-01

    The aim of this study was to review recent advances in the management of acquired cholesteatoma. All papers referring to acquired cholesteatoma management were identified in Medline via OVID (1948 to December 2013), PubMed (to December 2013), and Cochrane Library (to December 2013). A total of 86 papers were included in the review. Cholesteatoma surgery can be approached using either a canal wall up (CWU) or canal wall down (CWD) mastoidectomy with or without reconstruction of the middle ear cleft. In recent decades, a variety of surgical modifications have been developed including various "synthesis" techniques that combine the merits of CWU and CWD. The application of transcanal endoscopy has also recently gained popularity; however, difficulties associated with this approach remain, such as the need for one-handed surgery, the inability to provide continuous irrigation/suction, and limitations regarding endoscopic accessibility to the mastoid cavity. Additionally, several recent studies have reported successes in the application of laser-assisted cholesteatoma surgery, which overcomes the conflicting goals of eradicating disease and the preservation of hearing. Nevertheless, the risk of residual disease remains a challenge. Each of the techniques examined in this study presents pros and cons regarding final outcomes, such that any pronouncements regarding the superiority of one technique over another cannot yet be made. Flexibility in the selection of surgical methods according to the context of individual cases is essential in optimizing the outcomes.

  12. Inherited and acquired immunodeficiencies underlying tuberculosis in childhood

    Science.gov (United States)

    Boisson-Dupuis, Stéphanie; Bustamante, Jacinta; El-Baghdadi, Jamila; Camcioglu, Yildiz; Parvaneh, Nima; Azbaoui, Safaa El; Agader, Aomar; Hassani, Amal; Hafidi, Naima El; Mrani, Nidal Alaoui; Jouhadi, Zineb; Ailal, Fatima; Najib, Jilali; Reisli, Ismail; Zamani, Adil; Yosunkaya, Sebnem; Gulle-Girit, Saniye; Yildiran, Alisan; Cipe, Funda Erol; Torun, Selda Hancerli; Metin, Ayse; Atikan, Basak Yildiz; Hatipoglu, Nevin; Aydogmus, Cigdem; Kilic, Sara Sebnem; Dogu, Figen; Karaca, Neslihan; Aksu, Guzide; Kutukculer, Necil; Keser-Emiroglu, Melike; Somer, Ayper; Tanir, Gonul; Aytekin, Caner; Adimi, Parisa; Mahdaviani, Seyed Alireza; Mamishi, Setareh; Bousfiha, Aziz; Sanal, Ozden; Mansouri, Davood; Casanova, Jean-Laurent; Abel, Laurent

    2015-01-01

    Summary Tuberculosis (TB), caused by Mycobacterium tuberculosis (M.tb) and a few related mycobacteria, is a devastating disease, killing more than a million individuals per year worldwide. However, its pathogenesis remains largely elusive, as only a small proportion of infected individuals develop clinical disease either during primary infection or during reactivation from latency or secondary infection. Subacute, hematogenous, and extrapulmonary disease tends to be more frequent in infants, children, and teenagers than in adults. Life-threatening primary TB of childhood can result from known acquired or inherited immunodeficiencies, although the vast majority of cases remain unexplained. We review here the conditions conferring a predisposition to childhood clinical diseases caused by mycobacteria, including not only M.tb but also weakly virulent mycobacteria, such as BCG vaccines and environmental mycobacteria. Infections with weakly virulent mycobacteria are much rarer than TB, but the inherited and acquired immunodeficiencies underlying these infections are much better known. Their study has also provided genetic and immunological insights into childhood TB, as illustrated by the discovery of single-gene inborn errors of IFN-γ immunity underlying severe cases of TB. Novel findings are expected from ongoing and future human genetic studies of childhood TB in countries that combine a high proportion of consanguineous marriages, a high incidence of TB, and an excellent clinical care, such as Iran, Morocco, and Turkey. PMID:25703555

  13. Cardiomyopathy in congenital and acquired generalized lipodystrophy: a clinical assessment.

    Science.gov (United States)

    Lupsa, Beatrice C; Sachdev, Vandana; Lungu, Andreea O; Rosing, Douglas R; Gorden, Phillip

    2010-07-01

    Lipodystrophy is a rare disorder characterized by loss of adipose tissue and low leptin levels. This condition is characterized by severe dyslipidemia, insulin resistance, diabetes mellitus, and steatohepatitis. Another phenotypic feature that occurs with considerable frequency in generalized lipodystrophy is cardiomyopathy. We report here the cardiac findings in a cohort of patients with generalized congenital and acquired lipodystrophy, and present a literature review of the cardiac findings in patients with generalized lipodystrophy. We studied 44 patients with generalized congenital and acquired lipodystrophy, most of them enrolled in a clinical trial of leptin therapy. Patients underwent electrocardiograms and transthoracic echocardiograms to evaluate their cardiac status. We followed these patients for an extended time period, some of them up to 8 years. Evaluation of our cohort of patients with generalized lipodystrophy shows that cardiomyopathy is a frequent finding in this population. Most of our patients had hypertrophic cardiomyopathy, and only a small number had features of dilated cardiomyopathy. Hypertrophic cardiomyopathy was more frequent in patients with seipin mutation, a finding consistent with the literature. The underlying mechanism for cardiomyopathy in lipodystrophy is not clear. Extreme insulin resistance and the possibility of a "lipotoxic cardiomyopathy" should be entertained as possible explanations.

  14. Clinical features of endemic community-acquired psittacosis

    Directory of Open Access Journals (Sweden)

    J.M. Branley

    2014-01-01

    Full Text Available Following a large outbreak of community-acquired psittacosis in 2002 in residents of the Blue Mountains, New South Wales, Australia, we reviewed new cases in this area over a 7-year period from 2003 to 2009. Using the 2010 criteria from the Centers for Disease Control National Notifiable Diseases Surveillance System, 85 patients with possible psittacosis were identified, of which 48 were identified as definite or probable infection. Clinical features of these cases are summarized. In addition to Chlamydia-specific serology, specimens, where available, underwent nucleic acid testing for chlamydial DNA using real-time PCR. Chlamydophila psittaci DNA was detected in samples from 23 patients. Four of 18 specimens were culture positive. This is the first description of endemic psittacosis, and is characterized in this location by community-acquired psittacosis resulting from inadvertent exposure to birds. The disease is likely to be under-diagnosed, and may often be mistaken for gastroenteritis or meningitis given the frequency of non-respiratory symptoms, particularly without a history of contact with birds. Clinical characteristics of endemic and outbreak-associated cases were similar. The nature of exposure, risk factors and reasons for the occurrence of outbreaks of psittacosis require further investigation.

  15. Acquiring Ecg Signals And Analysing For Different Heart Ailments

    Directory of Open Access Journals (Sweden)

    B.Sravanthi

    2015-03-01

    Full Text Available This paper describes and focuses on acquiring and identification of cardiac diseases using ECG waveform in LabVIEW software, which would bridge the gap between engineers and medical physicians. This model work collects the waveform of an affected person. The waveform is analyzed for diseases and then a report is sent to the doctor through mail. Initially the waveforms are collected from the person using EKG sensor with the help of surface electrodes and the hardware controlled by MCU C8051, acquires ECG and also Phonocardiogram (PCG synchronously and the waveform is sent to the PC installed with LabVIEW software through DAQ-6211. The waveform in digital format is saved and sent to the loops containing conditions for different diseases. If the waveform parameters coincide with any of the looping statements, particular disease is indicated. Simultaneously the patient PCG report is also collected in a separate database containing all information, which will be sent to the doctor through mail.

  16. Acquired idiopathic laryngomalacia treated by laser supraglottic laryngoplasty.

    Science.gov (United States)

    Kawamoto, Ai; Katori, Yukio; Honkura, Yohei; Ogura, Masaki; Takanashi, Yoshitaka; Kobayashi, Toshimitsu

    2013-01-01

    Laryngomalacia is the most common cause of stridor in neonates and infants, where the soft cartilages and tissues surrounding the upper larynx collapse inward during respiration. On the other hand, acquired idiopathic laryngomalacia in adults is quite rare, but should be borne in mind for differential diagnosis of upper airway distress. Allergic factors may cause airway distress, but have not been highlighted previously as the background of laryngomalacia. In this report, we describe two patients with acquired idiopathic laryngomalacia with reference to allergic rhinitis and high serum levels of immunoglobulin E. The first patient was a 16-year-old female who presented with inspiratory stridor and dyspnea due to attachment between the epiglottis and bilateral arytenoids, and the second patient was an 18-year-old male who also presented with inspiratory stridor due to attachment between the epiglottis and posterior pharyngeal wall. The respiratory function of both patients was within the normal range but the inspiratory stridor interfered with daily life. Laryngomicrosurgery was performed in both patients using a CO2 laser to remove the arytenoid mucosa in the first patient, and to remove the tip of the epiglottis in the second. Both patients were followed up while receiving oral anti-allergic agents. Laser supraglottic laryngoplasty to remove the vibrating excess tissue was effective for resolving the symptoms. However, recurrence occurred three times in the first patient, and inferior turbinotomy to improve nasal respiration was useful for diminishing the symptoms. PMID:23728505

  17. Acquired von Willebrand syndrome: A rare disorder of heterogeneous etiology

    Directory of Open Access Journals (Sweden)

    P Kasatkar

    2013-01-01

    Full Text Available Context: Acquired von Willebrand syndrome (AVWS is a rare bleeding disorder that mimics the inherited form of von Willebrand disease (VWD in terms of laboratory findings and clinical presentation. Aims: To study the etiology of acquired VWD. Settings and Design: The patients referred from various hospitals in and out of Mumbai were included in the study. Materials and Methods: Six patients with AVWS diagnosed at this center over the last 10 years were analyzed against 171 patients with inherited VWD. The differential diagnosis of AVWS was made based on reduced levels of von Willebrand antigen and von Willebrand ristocetin cofactor, decrease in ristocetin induced platelet aggregation, absence of correction in mixing studies with no prior history of bleeding problems and a negative family history for bleeding disorders. Results: In three patients, the disease was associated with systematic lupus erythematosus, out of which one was also associated with Kikuchi lymphadenitis and second with autoimmune hemolytic anemia. Fourth case was associated with hypothyroidism and fifth was a case of dermatitis and vitiligo. The last patient was a case of hemophilia A with Burkitts lymphoma, who developed autoantibodies to von Willebrand factor. Except two patients, all other patients responded to immune suppressive therapy with corticosteroids, while the patient with hypothyroidism responded to oral thyroxine. Conclusion: AVWS is a rare condition and may often be missed or diagnosed as inherited disease associated with heterogeneous disease conditions.

  18. [CAPNETZ. The competence network for community-acquired pneumonia (CAP)].

    Science.gov (United States)

    Suttorp, Norbert; Welte, Tobias; Marre, Reinhard; Stenger, Steffen; Pletz, Mathias; Rupp, Jan; Schütte, Hartwig; Rohde, Gernot

    2016-04-01

    CAPNETZ is a medical competence network for community-acquired pneumonia (CAP), which was funded by the German Ministry for Education and Research. It has accomplished seminal work on pneumonia over the last 15 years. A unique infrastructure was established which has so far allowed us to recruit and analyze more than 11,000 patients. The CAPNETZ cohort is the largest cohort worldwide and the results obtained relate to all relevant aspects of CAP management (epidemiology, risk stratification via biomarkers or clinical scores, pathogen spectrum, pathogen resistance, antibiotic management, prevention and health care research). Results were published in more than 150 journals and informed the preparation and update of the national S3-guideline. CAPNETZ was also the foundation for further networks like the Pneumonia Research Network on Genetic Resistance and Susceptibility for the Evolution of Severe Sepsis) (PROGRESS), the Systems Medicine of Community Acquired Pneumonia Network (CAPSyS) and SFB-TR84 (Sonderforschungsbereich - Transregio 84). The main recipients (Charité Berlin, University Clinic Ulm and the Hannover Medical School) founded the CAPNETZ foundation and transferred all data and materials rights to this foundation. Moreover, the ministry granted the CAPNETZ foundation the status of being eligible to apply for research proposals and receive research funds. Since 2013 the CAPNETZ foundation has been an associated member of the German Center for Lung Research (DZL). Thus, a solid foundation has been set up for CAPNETZ to continue its success story. PMID:26984399

  19. Cosmic ray runs acquired with ATLAS muon stations

    CERN Multimedia

    Cerutti, F.

    Starting in the fall 2005 several cosmic ray runs have been acquired in the ATLAS pit with six muon stations. These were three large outer and three large middle chambers of the feet sector (sector 13) that have been readout in the ATLAS cavern. In the first data taking period the trigger was based on two large scintillators (~300x30 cm2) positioned in sector 13 just below the large chambers. In this first run the precision chambers (the Monitored Drift Tubes) were operated in a close to final configuration. Typical trigger rates with this setup were of the order of 1 Hz. Several data sets of 10k events were acquired with final electronics up to the muon ROD and analysed with ATHENA-based software. These data allowed the first checks of the functionality and efficiency of the MDT stations in the ATLAS pit and the first measurement of the FE electronics noise in the ATLAS environment. A few event were also collected in a combined run with the TILE barrel calorimeter. An event display of a cosmic ray a...

  20. Image domain propeller fast spin echo☆

    OpenAIRE

    Skare, Stefan; Holdsworth, Samantha J.; Lilja, Anders; Bammer, Roland

    2012-01-01

    A new pulse sequence for high-resolution T2-weighted (T2-w) imaging is proposed –image domain propeller fast spin echo (iProp-FSE). Similar to the T2-w PROPELLER sequence, iProp-FSE acquires data in a segmented fashion, as blades that are acquired in multiple TRs. However, the iProp-FSE blades are formed in the image domain instead of in the k-space domain. Each iProp-FSE blade resembles a single-shot fast spin echo (SSFSE) sequence with a very narrow phase-encoding field of view (FOV), after...

  1. Quantitative imaging features: extension of the oncology medical image database

    Science.gov (United States)

    Patel, M. N.; Looney, P. T.; Young, K. C.; Halling-Brown, M. D.

    2015-03-01

    Radiological imaging is fundamental within the healthcare industry and has become routinely adopted for diagnosis, disease monitoring and treatment planning. With the advent of digital imaging modalities and the rapid growth in both diagnostic and therapeutic imaging, the ability to be able to harness this large influx of data is of paramount importance. The Oncology Medical Image Database (OMI-DB) was created to provide a centralized, fully annotated dataset for research. The database contains both processed and unprocessed images, associated data, and annotations and where applicable expert determined ground truths describing features of interest. Medical imaging provides the ability to detect and localize many changes that are important to determine whether a disease is present or a therapy is effective by depicting alterations in anatomic, physiologic, biochemical or molecular processes. Quantitative imaging features are sensitive, specific, accurate and reproducible imaging measures of these changes. Here, we describe an extension to the OMI-DB whereby a range of imaging features and descriptors are pre-calculated using a high throughput approach. The ability to calculate multiple imaging features and data from the acquired images would be valuable and facilitate further research applications investigating detection, prognosis, and classification. The resultant data store contains more than 10 million quantitative features as well as features derived from CAD predictions. Theses data can be used to build predictive models to aid image classification, treatment response assessment as well as to identify prognostic imaging biomarkers.

  2. Imaging longitudinal cardiac strain on short-axis images using 3D HARP

    Science.gov (United States)

    Osman, Nael F.; Sampath, Smita; Prince, Jerry L.

    2000-04-01

    This paper presents a new method for measuring longitudinal strain of the heart using harmonic phase magnetic resonance imaging (HARP-MRI). The heart is tagged using 1-1 SPAMM at end-diastole with tagging surfaces parallel to the imaging plane. Two image sequences are acquired for a short-axis slice with two different encodings in the direction orthogonal to the imaging plane. A method to compute a sequence of longitudinal strain estimates from this data is described.

  3. Image Reconstruction. Chapter 13

    International Nuclear Information System (INIS)

    This chapter discusses how 2‑D or 3‑D images of tracer distribution can be reconstructed from a series of so-called projection images acquired with a gamma camera or a positron emission tomography (PET) system [13.1]. This is often called an ‘inverse problem’. The reconstruction is the inverse of the acquisition. The reconstruction is called an inverse problem because making software to compute the true tracer distribution from the acquired data turns out to be more difficult than the ‘forward’ direction, i.e. making software to simulate the acquisition. There are basically two approaches to image reconstruction: analytical reconstruction and iterative reconstruction. The analytical approach is based on mathematical inversion, yielding efficient, non-iterative reconstruction algorithms. In the iterative approach, the reconstruction problem is reduced to computing a finite number of image values from a finite number of measurements. That simplification enables the use of iterative instead of mathematical inversion. Iterative inversion tends to require more computer power, but it can cope with more complex (and hopefully more accurate) models of the acquisition process

  4. Failure of levofloxacin treatment in community-acquired pneumococcal pneumonia

    Directory of Open Access Journals (Sweden)

    Grossi Paolo

    2005-11-01

    Full Text Available Abstract Background Streptococcus pneumoniae is the leading cause of community-acquired pneumonia (CAP. High global incidence of macrolide and penicillin resistance has been reported, whereas fluoroquinolone resistance is uncommon. Current guidelines for suspected CAP in patients with co-morbidity factors and recent antibiotic therapy recommend initial empiric therapy using one fluoroquinolone or one macrolide associated to other drugs (amoxicillin, amoxicillin/clavulanate, broad-spectrum cephalosporins. Resistance to fluoroquinolones is determined by efflux mechanisms and/or mutations in the parC and parE genes coding for topoisomerase IV and/or gyrA and gyrB genes coding for DNA gyrase. No clinical cases due to fluoroquinolone-resistant S. pneumoniae strains have been yet reported from Italy. Case presentation A 72-year-old patient with long history of chronic obstructive pulmonary disease and multiple fluoroquinolone treatments for recurrent lower respiratory tract infections developed fever, increased sputum production, and dyspnea. He was treated with oral levofloxacin (500 mg bid. Three days later, because of acute respiratory insufficiency, the patient was hospitalized. Levofloxacin treatment was supplemented with piperacillin/tazobactam. Microbiological tests detected a S. pneumoniae strain intermediate to penicillin (MIC, 1 mg/L and resistant to macrolides (MIC >256 mg/L and fluoroquinolones (MIC >32 mg/L. Point mutations were detected in gyrA (Ser81-Phe, parE (Ile460-Val, and parC gene (Ser79-Phe; Lys137-Asn. Complete clinical response followed treatment with piperacillin/tazobactam. Conclusion This is the first Italian case of community-acquired pneumonia due to a fluoroquinolone-resistant S. pneumoniae isolate where treatment failure of levofloxacin was documented. Molecular analysis showed a group of mutations that have not yet been reported from Italy and has been detected only twice in Europe. Treatment with piperacillin

  5. Face and facial parts tracking for acquiring nonverbal information

    Science.gov (United States)

    Funahashi, Takuma; Fujiwara, Takayuki; Koshimizu, Hiroyasu

    2005-12-01

    Since, at our laboratory, the basic configuration of the facial caricaturing system PICASSO has been constructed, it is strongly expected to get sufficient input image from a person who is naturally performing in front of the PICASSO camera system. From this viewpoint, we developed a face tracking PC system for capturing sufficient facial image especially in size by means of PTZ (Pan-Tilt-Zoom) camera collaborated with a fixed CCD camera. Irises are successfully recognized from the motion images captured from PTZ camera. These irises can be utilized to provide a key feature for realizing an automated facial recognizing system. In this system, a person performing naturally in pose and in facial expression within the scope of the fixed CCD camera can be stably tracked and the sufficient images in resolution of PTZ camera were successfully analyzed for iris recognition and facial parts extractions. This face tracking and face recognition system was characterized by a novel template replacement scheme among the successive image frames. Experimental results were also demonstrated in this paper. This system works well in a practical speed 6-9fps on a usual PC connected to these cameras.

  6. Episode image analysis for wearable daily life recording system

    Science.gov (United States)

    Toda, Masashi; Nagasaki, Takeshi; Kawashima, Toshio

    2003-06-01

    Now we are developing a wearable recording system which can capture images from user"s view point in user"s everyday life automatically. The user refers to the images which is acquired using this system later, and these images support a user"s activity, such as human memory and human thoughts. Amount images which are acquired becomes so huge that it is difficult for the user to refer them. So the mechanism for viewing effectively is very important, such as summary. In this research, we describe the concept for summary mechanism of everyday life images.

  7. Acquired CNS lesions in fetal MRI; Erworbene ZNS-Laesionen im fetalen MRT

    Energy Technology Data Exchange (ETDEWEB)

    Reith, W.; Pogledic, I. [Universitaetsklinikum des Saarlandes, Homburg/Saar, Klinik fuer Diagnostische und Interventionelle Neuroradiologie, Homburg/Saar (Germany)

    2013-02-15

    Acquired central nervous system (CNS) lesions are often subtle; therefore, the prenatal diagnosis of these lesions is extremely important. The fetal ultrasound examination and magnetic resonance imaging (MRI) are two important imaging methods that give an insight into these types lesions. The method of choice during pregnancy is still fetal ultrasound; however, fetal MRI is important when there are certain pathologies, e.g. periventricular leukomalacia (PVL) or malformations of the vein of Galen. In this manner clinicians can plan further therapy after childbirth in advance (e.g. cerebral angiography or embolization). (orig.) [German] Die erworbenen ZNS-Laesionen sind oft subtil, und eine praezise praenatale Diagnostik ist in diesen Faellen besonders wichtig. Die fetale Sonographie und das fetale MRT koennen hierzu einen relevanten Beitrag leisten. Die Sonographie ist immer noch die Untersuchungsmethode der Wahl waehrend der Schwangerschaft. Insbesondere bei bestimmten Pathologien wie der periventrikulaeren Leukomalazie (PVL) oder einer V. -Galeni-Malformation ist das fetale MRT sehr hilfreich, um nach der Geburt die entsprechenden weitergehenden Massnahmen, wie eine zerebrale Angiographie und Embolisation, fruehzeitig zu planen. (orig.)

  8. Rotationally acquired 4D-optical coherence tomography of embryonic chick hearts using retrospective gating on the common central A-scan

    DEFF Research Database (Denmark)

    Thommes, Jan; Happel, Christoph M.; Thrane, Lars;

    2010-01-01

    is used for this purpose, e.g. in MRT or CT of human hearts. For visualization of embryonic chick hearts with high-resolution optical coherence tomography (OCT), a gating trigger generated by laser Doppler velocimetry has been successfully demonstrated (1). But this takes time and adds to system......In vivo analysis of cardiac physiology and non-invasive imaging of the beating early embryonic heart in 2 and 3D remain a challenge in cardiovascular development research. 3D-imaging of the beating heart relies on gating of the acquired images according to the cardiac cycle. Mostly ECG triggering...

  9. Rotationally acquired 4D-optical coherence tomography of embryonic chick hearts using retrospective gating on the common central A-scan

    OpenAIRE

    Thommes, Jan; Happel, Christoph M.; Thrane, Lars; Yelbuz, T. Mesud

    2010-01-01

    In vivo analysis of cardiac physiology and non-invasive imaging of the beating early embryonic heart in 2 and 3D remain a challenge in cardiovascular development research. 3D-imaging of the beating heart relies on gating of the acquired images according to the cardiac cycle. Mostly ECG triggering is used for this purpose, e.g. in MRT or CT of human hearts. For visualization of embryonic chick hearts with high-resolution optical coherence tomography (OCT), a gating trigger generated by laser D...

  10. The etiology of primary femoroacetabular impingement: genetics or acquired deformity?

    Science.gov (United States)

    Packer, Jonathan D; Safran, Marc R

    2015-10-01

    The etiology of primary femoroacetabular impingement (FAI) remains controversial. Both genetic and acquired causes have been postulated and studied. While recent studies suggest that genetic factors may have a role in the development of FAI, there is no conclusive evidence that FAI is transmitted genetically. Currently, the most popular theory for the development of cam-type deformities is that a repetitive injury to the proximal femoral physis occurs during a critical period of development. There is a correlation between a high volume of impact activities during adolescence and the development of cam-type deformities. Multiple studies have found a high prevalence of FAI in elite football, ice hockey, basketball and soccer players. In this article, we review the current literature relating to the etiology of primary FAI.

  11. The etiology of primary femoroacetabular impingement: genetics or acquired deformity?

    Science.gov (United States)

    Packer, Jonathan D.; Safran, Marc R.

    2015-01-01

    The etiology of primary femoroacetabular impingement (FAI) remains controversial. Both genetic and acquired causes have been postulated and studied. While recent studies suggest that genetic factors may have a role in the development of FAI, there is no conclusive evidence that FAI is transmitted genetically. Currently, the most popular theory for the development of cam-type deformities is that a repetitive injury to the proximal femoral physis occurs during a critical period of development. There is a correlation between a high volume of impact activities during adolescence and the development of cam-type deformities. Multiple studies have found a high prevalence of FAI in elite football, ice hockey, basketball and soccer players. In this article, we review the current literature relating to the etiology of primary FAI. PMID:27011846

  12. Acquired pure red cell aplasia in a child.

    Directory of Open Access Journals (Sweden)

    Sharma R

    2002-01-01

    Full Text Available Primary acquired pure red cell aplasia is a rare occurrence in childhood. An eleven-year old boy presented to us with pallor, which required multiple packed red cell transfusions. He did not have hepatosplenomegaly, jaundice or lymphadenopathy. Bone marrow examination revealed the diagnosis of pure red cell aplasia. All possible investigations were done to exclude secondary causes of pure red cell aplasia. No secondary cause was found on investigations. Rheumatoid factor and anti-nuclear antibodies were positive. He was started on oral steroids, to which he did not respond. He was then given cyclosporine A. Response to cyclosporine was dramatic and the child now does not require any transfusions.

  13. The etiology of primary femoroacetabular impingement: genetics or acquired deformity?

    Science.gov (United States)

    Packer, Jonathan D; Safran, Marc R

    2015-10-01

    The etiology of primary femoroacetabular impingement (FAI) remains controversial. Both genetic and acquired causes have been postulated and studied. While recent studies suggest that genetic factors may have a role in the development of FAI, there is no conclusive evidence that FAI is transmitted genetically. Currently, the most popular theory for the development of cam-type deformities is that a repetitive injury to the proximal femoral physis occurs during a critical period of development. There is a correlation between a high volume of impact activities during adolescence and the development of cam-type deformities. Multiple studies have found a high prevalence of FAI in elite football, ice hockey, basketball and soccer players. In this article, we review the current literature relating to the etiology of primary FAI. PMID:27011846

  14. Transfer of Juggling Skills Acquired in a Virtual Environment

    DEFF Research Database (Denmark)

    Hauge, Alex Patrick; Kragegaard, Christian Skriver; Kjæhr, Emil Bering;

    2013-01-01

    This paper explores whether motoric skills acquired within a virtual training environment can be successfully transferred to the real world by comparing a virtual environment with a traditional learning environment. Specifically, a system for learning juggling with virtual balls was designed...... with a focus on approximating natural interaction. We propose a method of evaluating the acquisition and transfer of motoric skills through a virtual environment, which is compared to a traditional learning environment. Each environment was evaluated using various criteria ranging from improvement in skills...... to observations of performance. The findings suggest that a transfer of motoric skills and knowledge takes place for users of the virtual system with only little difference between the environments. They also suggest that a virtual environment can create a less frustrating learning experience....

  15. Severe Dermatophytosis and Acquired or Innate Immunodeficiency: A Review

    Directory of Open Access Journals (Sweden)

    Claire Rouzaud

    2015-12-01

    Full Text Available Dermatophytes are keratinophilic fungi responsible for benign and common forms of infection worldwide. However, they can lead to rare and severe diseases in immunocompromised patients. Severe forms include extensive and/or invasive dermatophytosis, i.e., deep dermatophytosis and Majocchi’s granuloma. They are reported in immunocompromised hosts with primary (autosomal recessive CARD9 deficiency or acquired (solid organ transplantation, autoimmune diseases requiring immunosuppressive treatments, HIV infection immunodeficiencies. The clinical manifestations of the infection are not specific. Lymph node and organ involvement may also occur. Diagnosis requires both mycological and histological findings. There is no consensus on treatment. Systemic antifungal agents such as terbinafine and azoles (itraconazole or posaconazole are effective. However, long-term outcome and treatment management depend on the site and extent of the infection and the nature of the underlying immunodeficiency.

  16. CLINICAL-EPIDEMIOLOGICAL ISSUES OF ACQUIRED CHILD METHEMOGLOBINEMIA

    Directory of Open Access Journals (Sweden)

    Letiția-Doina DUCEAC

    2016-03-01

    Full Text Available Nowadays, intoxication with nitrates continues to represent an important aspect in child pathology. Methemoglobinemia symptoms appear when the human body is exposed to high amounts of toxic compounds.The aim of this work was to evaluate the main clinical, biological and development issues of affected patients hospitalized in a specialized clinic. Acquired methemoglobinemia cases of the ”blue child syndrome” type are more frequent than in born ones. The factors considered for the study were the environment from which patients came, a thorough clinical inspection, data on age, nutrition, methemoglobinemia values, other treatments followed, associated diseases and evolution prognosis. The conclusion of the investigation was that a low living standard, a poor health education, the climate, the presence of ground fertilizers and the type of nourishment determined a significant increase of methemoglobinemia patients.

  17. Systemic Acquired Resistance and Signal Transduction in Plant

    Institute of Scientific and Technical Information of China (English)

    ZHAO Shu-qing; GUO Jian-bo

    2003-01-01

    Systemic acquired resistance (SAR), known as the broad-spectrum, inducible plant immunity,is a defense response triggered by pathogen infection. The response starts from the recognition of plant resist-ance (R) with the corresponding avirulence (avr) gene from the pathogen. There are some genes for conver-gence of signals downstream of different R/avr interacting partners into a single signaling pathway. Salicylicacid (SA) is required for the induction of SAR and involved in transducing the signal in target tissues. The SAsignal is transduced through NPR1, a nuclear-localized protein that interacts with transcription factors thatare involved in regulating SA-mediated gene expression. Some chemicals that mimic natural signaling com-pounds can also activate SAR. The application of biochemical activators to agriculture for plant protection is anovel idea for developing green chemical pesticide.

  18. CNOOC Acquires Oilfield Assets in Indonesia from Repsol-YPF

    Institute of Scientific and Technical Information of China (English)

    Wang Yiwen

    2002-01-01

    @@ CNOOC Limited has recently agreed with the Repsol-YPF group on acquisition of the interests in five oil fields in Indonesia at the cost of US$585million. The assets to be acquired include an aggregate 65.34 percent interest in the Southeast Sumatra PSC, an aggregate 36.72 percent interest in the Offshore Northwest Java PSC, a 25 percent interest in the West Madura PSC, a 50 percent interest in the Poleng TAC and a 16.7 percent interest in the Blora PSC. This acquisition, which helps the Chinese oil company get access to 360 million barrels of proven reserves in total, has made CNOOC Limited the largest offshore oil producer in Indonesia.

  19. Anthracyclines and Acquired Long QT Syndrome. A Case Report

    Directory of Open Access Journals (Sweden)

    Carlos Rodríguez Armada

    2014-12-01

    Full Text Available Acquired long QT syndrome results from secondary causes and can be caused by more than 100 non-antiarrhythmic drugs. Cardiac arrest due to Torsades de pointes induced by drugs causing prolonged QT syndrome is a rare but potentially fatal event, even in hospitals. The case of a 47-year-old patient diagnosed with non-Hodgkin lymphoma admitted to the hematology department of the Dr. Gustavo Aldereguía Lima University General Hospital in Cienfuegos is presented. The patient had been previously treated with anthracyclines and developed episodes of palpitations and syncope later. The treatment included monitoring the patient, avoiding other QT prolonging agents and administrating magnesium sulfate and potassium chloride with a proper maintenance of the fluid and acid-base balance. The presentation of this case aims at motivating interest in new reports on the subject and establishing a direct causal relationship through the evidence provided by new experiences.

  20. Acquired arteriovenous fistula in a grizzly bear (Ursus arctos horribilis).

    Science.gov (United States)

    Tuttle, Allison D; MacLean, Robert A; Linder, Keith; Cullen, John M; Wolfe, Barbara A; Loomis, Michael

    2009-03-01

    A captive adult male grizzly bear (Ursus arctos horribilis) was evaluated due to multifocal wounds of the skin and subcutaneous tissues sustained as a result of trauma from another grizzly bear. On presentation, one lesion that was located in the perineal region seemed to be a deep puncture with purple tissue protruding from it. This perineal wound did not heal in the same manner or rate as did the other wounds. Twenty-five days after initial detection, substantial active hemorrhage from the lesion occurred and necessitated anesthesia for examination of the bear. The entire lesion was surgically excised, which later proved curative. An acquired arteriovenous fistula was diagnosed via histopathology. Arteriovenous fistulas can develop after traumatic injury and should be considered as a potential complication in bears with nonhealing wounds.

  1. Acquiring, encoding, and re-using clinical knowledge in PRODIGY

    Directory of Open Access Journals (Sweden)

    Richard Hall

    2002-11-01

    Full Text Available The development, implementation and maintenance of computer-executable clinical guidelines encompass a series of complex processes. As they are often performed by more than one organisation, this introduces further complexity. Within the PRODIGY project we attempt to control as many aspects of the process as possible, in order to increase the likelihood of achieving success. To illustrate the complexity of the process and many of the inherent problems and solutions, this paper describes the evolution of the PRODIGY knowledge base, describing the steps from acquiring knowledge, through encoding, to the execution of guidelines, and 'closing the loop' by discussing an approach to knowledge re-use. We will also consider some of the wider implications of our work and propose directions for future research and development activities.

  2. Music Therapy, Acquired Brain Injury and Interpersonal Communication Competencies

    DEFF Research Database (Denmark)

    Hald, Søren

    2012-01-01

    Acquired brain injury (ABI) often affects physical, cognitive and psychological aspects of a person's functioning (Bateman, et al., 2010). Psychosocial problems associated with ABI may be the major challenge facing the rehabilitation process (Morton & Wehman, 1995) Consequently, interventions...... that music is a useful tool to stimulate interaction since musical interaction can be engaged at almost any cognitive and physical level and still be meaningful (Baker & Tamplin, 2006; Gilbertson, 2005; Hald, 2011). In addition, music therapy researchers specialising in ABI have found that: - Music therapy...... is a powerful means to improve communication, general behavior, and musical behavior (Purdie, Hamilton & Baldwin, 1997). - Music therapy can increase emotional stability, clarify thoughts, stimulate spontaneous interaction, and increase motivation and cooperation (Nayak, Wheeler, Shiflett & Agostinelli, 2000...

  3. A method for the reconstruction of four-dimensional synchronized CT scans acquired during free breathing

    International Nuclear Information System (INIS)

    Breathing motion is a significant source of error in radiotherapy treatment planning for the thorax and upper abdomen. Accounting for breathing motion has a profound effect on the size of conformal radiation portals employed in these sites. Breathing motion also causes artifacts and distortions in treatment planning computed tomography (CT) scans acquired during free breathing and also causes a breakdown of the assumption of the superposition of radiation portals in intensity-modulated radiation therapy, possibly leading to significant dose delivery errors. Proposed voluntary and involuntary breath-hold techniques have the potential for reducing or eliminating the effects of breathing motion, however, they are limited in practice, by the fact that many lung cancer patients cannot tolerate holding their breath. We present an alternative solution to accounting for breathing motion in radiotherapy treatment planning, where multislice CT scans are collected simultaneously with digital spirometry over many free breathing cycles to create a four-dimensional (4-D) image set, where tidal lung volume is the additional dimension. An analysis of this 4-D data leads to methods for digital-spirometry, based elimination or accounting of breathing motion artifacts in radiotherapy treatment planning for free breathing patients. The 4-D image set is generated by sorting free-breathing multislice CT scans according to user-defined tidal-volume bins. A multislice CT scanner is operated in the cine mode, acquiring 15 scans per couch position, while the patient undergoes simultaneous digital-spirometry measurements. The spirometry is used to retrospectively sort the CT scans by their correlated tidal lung volume within the patient's normal breathing cycle. This method has been prototyped using data from three lung cancer patients. The actual tidal lung volumes agreed with the specified bin volumes within standard deviations ranging between 22 and 33 cm3. An analysis of sagittal and

  4. Acquiring neural signals for developing a perception and cognition model

    Science.gov (United States)

    Li, Wei; Li, Yunyi; Chen, Genshe; Shen, Dan; Blasch, Erik; Pham, Khanh; Lynch, Robert

    2012-06-01

    The understanding of how humans process information, determine salience, and combine seemingly unrelated information is essential to automated processing of large amounts of information that is partially relevant, or of unknown relevance. Recent neurological science research in human perception, and in information science regarding contextbased modeling, provides us with a theoretical basis for using a bottom-up approach for automating the management of large amounts of information in ways directly useful for human operators. However, integration of human intelligence into a game theoretic framework for dynamic and adaptive decision support needs a perception and cognition model. For the purpose of cognitive modeling, we present a brain-computer-interface (BCI) based humanoid robot system to acquire brainwaves during human mental activities of imagining a humanoid robot-walking behavior. We use the neural signals to investigate relationships between complex humanoid robot behaviors and human mental activities for developing the perception and cognition model. The BCI system consists of a data acquisition unit with an electroencephalograph (EEG), a humanoid robot, and a charge couple CCD camera. An EEG electrode cup acquires brainwaves from the skin surface on scalp. The humanoid robot has 20 degrees of freedom (DOFs); 12 DOFs located on hips, knees, and ankles for humanoid robot walking, 6 DOFs on shoulders and arms for arms motion, and 2 DOFs for head yaw and pitch motion. The CCD camera takes video clips of the human subject's hand postures to identify mental activities that are correlated to the robot-walking behaviors. We use the neural signals to investigate relationships between complex humanoid robot behaviors and human mental activities for developing the perception and cognition model.

  5. Inducible and Acquired Clarithromycin Resistance in the Mycobacterium abscessus Complex.

    Directory of Open Access Journals (Sweden)

    Marc Rubio

    Full Text Available Clarithromycin was considered the cornerstone for the treatment of Mycobacterium abscessus complex infections. Genetic resistance mechanisms have been described and many experts propose amikacin as an alternative. Nevertheless, clarithromycin has several advantages; therefore, it is necessary to identify the non-functional erm(41 allele to determine the most suitable treatment. The aims of this study were to characterize the molecular mechanisms of clarithromycin resistance in a collection of Mycobacterium abscessus complex isolates and to verify the relationship between these mechanisms and the antibiogram.Clinical isolates of M. abscessus complex (n = 22 from 16 patients were identified using four housekeeping genes (rpoB, secA1, sodA and hsp65, and their genetic resistance was characterized by studying erm(41 and rrl genes. Nine strains were recovered from the clinical isolates and subjected to E-test and microdilution clarithromycin susceptibility tests, with readings at 3, 7 and 14 days.We classified 11/16 (68.8% M. abscessus subsp. abscessus, 4/16 (25.0% M. abscessus subsp. bolletii, and 1/16 (6.3% M. abscessus subsp. massiliense. T28 erm(41 allele was observed in 8 Mycobacterium abscessus subps. abscessus and 3 Mycobacterium abscessus subsp. bolletii. One strain of M. abscessus subsp. bolletii had an erm(41 gene truncated and was susceptible to clarithromycin. No mutations were observed in rrl gene first isolates. In three patients, follow-up of initial rrl wild-type strains showed acquired resistance.Most clinical isolates of M. abscessus complex had inducible resistance to clarithromycin and total absence of constitutive resistance. Our findings showed that the acquisition of resistance mutations in rrl gene was associated with functional and non-functional erm(41 gene. Caution is needed when using erm(41 sequencing alone to identify M. abscessus subspecies. This study reports an acquired mutation at position 2057 of rrl gene

  6. Nodes of ranvier and paranodes in chronic acquired neuropathies.

    Directory of Open Access Journals (Sweden)

    Carmen Cifuentes-Diaz

    Full Text Available Chronic acquired neuropathies of unknown origin are classified as chronic inflammatory demyelinating polyneuropathies (CIDP and chronic idiopathic axonal polyneuropathies (CIAP. The diagnosis can be very difficult, although it has important therapeutic implications since CIDP can be improved by immunomodulating treatment. The aim of this study was to examine the possible abnormalities of nodal and paranodal regions in these two types of neuropathies. Longitudinal sections of superficial peroneal nerves were obtained from biopsy material from 12 patients with CIDP and 10 patients with CIAP and studied by immunofluorescence and in some cases electron microscopy. Electron microscopy revealed multiple alterations in the nodal and paranodal regions which predominated in Schwann cells in CIDP and in axons in CIAP. In CIDP paranodin/Caspr immunofluorescence was more widespread than in control nerves, extending along the axon in internodes where it appeared intense. Nodal channels Nav and KCNQ2 were less altered but were also detected in the internodes. In CIAP paranodes, paranodin labeling was irregular and/or decreased. To test the consequences of acquired primary Schwann cells alteration on axonal proteins, we used a mouse model based on induced deletion of the transcription factor Krox-20 gene. In the demyelinated sciatic nerves of these mice we observed alterations similar to those found in CIDP by immunofluorescence, and immunoblotting demonstrated increased levels of paranodin. Finally we examined whether the alterations in paranodin immunoreactivity could have a diagnosis value. In a sample of 16 biopsies, the study of paranodin immunofluorescence by blind evaluators led to correct diagnosis in 70 ± 4% of the cases. This study characterizes for the first time the abnormalities of nodes of Ranvier in CIAP and CIDP, and the altered expression and distribution of nodal and paranodal proteins. Marked differences were observed between CIDP and CIAP

  7. Cellular memory of acquired stress resistance in Saccharomyces cerevisiae.

    Science.gov (United States)

    Guan, Qiaoning; Haroon, Suraiya; Bravo, Diego González; Will, Jessica L; Gasch, Audrey P

    2012-10-01

    Cellular memory of past experiences has been observed in several organisms and across a variety of experiences, including bacteria "remembering" prior nutritional status and amoeba "learning" to anticipate future environmental conditions. Here, we show that Saccharomyces cerevisiae maintains a multifaceted memory of prior stress exposure. We previously demonstrated that yeast cells exposed to a mild dose of salt acquire subsequent tolerance to severe doses of H(2)O(2). We set out to characterize the retention of acquired tolerance and in the process uncovered two distinct aspects of cellular memory. First, we found that H(2)O(2) resistance persisted for four to five generations after cells were removed from the prior salt treatment and was transmitted to daughter cells that never directly experienced the pretreatment. Maintenance of this memory did not require nascent protein synthesis after the initial salt pretreatment, but rather required long-lived cytosolic catalase Ctt1p that was synthesized during salt exposure and then distributed to daughter cells during subsequent cell divisions. In addition to and separable from the memory of H(2)O(2) resistance, these cells also displayed a faster gene-expression response to subsequent stress at >1000 genes, representing transcriptional memory. The faster gene-expression response requires the nuclear pore component Nup42p and serves an important function by facilitating faster reacquisition of H(2)O(2) tolerance after a second cycle of salt exposure. Memory of prior stress exposure likely provides a significant advantage to microbial populations living in ever-changing environments. PMID:22851651

  8. Optimizing Synthetic Aperture Compound Imaging

    DEFF Research Database (Denmark)

    Hansen, Jens Munk; Jensen, Jørgen Arendt

    2012-01-01

    Spatial compound images are constructed from synthetic aperture data acquired using a linear phased-array transducer. Compound images of wires, tissue, and cysts are created using a method, which allows both transmit and receive compounding without any loss in temporal resolution. Similarly to...... optimal for lesion detection. Synthetic aperture data are acquired from unfocused emissions and 154 compound images are constructed by synthesizing different aperture configurations with more or less compounding, all maintaining a constant resolution across depth corresponding to an f-number of 2.0 for...... transmit and receive. The same configurations are used for scanning a phantom with cysts, and it is demonstrated how an improved cysts contrast follows from an aperture configuration, which gives a higher value for the performance measure extracted from the phantom without cysts. A correlation value R = 0...

  9. Real-time image acquisition and deblurring for underwater gravel extraction by smartphone

    Directory of Open Access Journals (Sweden)

    Ming-Fu Chen

    2014-02-01

    Full Text Available Gravel size distribution is an important aspect of stream investigation. Using water photography to determine such distribution is a simple and cost-effective approach for gathering instream gravel information. However, good-quality images of underwater gravels in shallow areas are difficult to acquire because of the flow- and wind-induced perturbation at water surface. Thus, two Lucy–Richardson iterations are applied on an averaged image to obtain a deblurred image for gravel extraction. A Matlab code for multi-frame image averaging and image deblurring is implemented on a laptop computer. Underwater gravel images are acquired using a video camera and processed offline. Thus, the usability of the images acquired during field investigation cannot be determined immediately. However, returning to the investigated streams for additional data gathering would be costly, and the cameras may accidentally be dropped into the water. This paper presents multi-frame image averaging and image deblurring smartphone-based approaches for underwater gravel extraction. A waterproof smartphone is used to acquire the images, on which image deblurring is immediately conducted to test whether the images can be used for gravel extraction. The averaged image of using mean-based filter is derived during real-time image acquisition. The deblurred image is derived block-by-block because of limited memory capacity of smartphones. The time consumed for acquiring 1500 frame images with size of 1280 × 720 pixels is approximately 6 min by Sony Xperia smartphones. Image averaging can be performed in real time during image acquisition. Image deblurring is accomplished accurately and is consistent with results of the Matlab code. The processing time for image deblurring is approximately 12 min. A compact system for underwater gravel investigation using smartphones is successfully developed in this study. Image acquisition and deblurring are completed in real time at the

  10. Using a controlled pressure field emission gun scanning electron microscope to acquire EBSD data on non-conductive samples

    International Nuclear Information System (INIS)

    The present work is dealing with electron backscattered diffraction. It is well known that EBSD requires most of the time and up to now, both an important high voltage and a large beam current. However, in such conditions, acquiring EBSD maps on non-conductive samples require to either coat the sample with a conductive thin layer or to use a controlled pressure SEM and then introduce some gas in the sample chamber. The idea here is to present some data comparisons between both solutions. Patterns, orientation images and simulations were carried out to try to access meaningful quantitative results.

  11. Space Acquired Photo = Gemini, Skylab, Shuttle Large Format Camera: 1965 - 1984

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — The Space Acquired Photography includes imagery from the Shuttle Large Format Camera, Skylab, and Gemini missions. The Space Acquired archive contains...

  12. High resolution visible continuum imaging diagnostic on the Alcator C-Mod tokamak

    Energy Technology Data Exchange (ETDEWEB)

    Marmar, E. S.; Boivin, R. L.; Granetz, R. S.; Hughes, J. W.; Lipschultz, B.; McCool, S.; Mossessian, D.; Pitcher, C. S.; Rice, J. E.; Terry, J. L.

    2001-01-01

    A high spatial resolution CCD based one-dimensional imaging system to measure visible continuum emissivity profiles from Alcator C-Mod tokamak plasmas is described. The instrument has chordal resolution that is better than 1 mm for the edge region of the plasma, where very sharp (1 to 10 mm) gradient lengths in plasma parameters are observed after the formation of the H-mode transport barrier. Each image has up to 2048 pixels, and total spatial coverage goes from 2 cm inside of the magnetic axis to {approx}4 cm outside of the last closed flux surface in the {approx}22 cm horizontal minor radius plasmas. Time resolution can be varied from 0.21 ms to 4 ms; good signal to noise is achieved with 1 ms integration under typical plasma conditions. The emission over most of the plasma volume is dominated by free--free bremsstrahlung, and can be used to infer local values of the average ion charge (Z{sub eff}). Toroidally localized puffing of deuterium, nitrogen, and helium reveals that a significant contribution to the signal in the scrape-off layer at the extreme edge of the plasma can come from diatomic molecular band pseudocontinuum emission.

  13. Fluoroscopy without image intensifier

    International Nuclear Information System (INIS)

    The objective of the present work was to evaluate the doses received by patients during fluoroscopy procedures carried out with an equipment without image intensifier. This evaluation is providing dose levels that our patients are presently exposed, and gives the data for epidemiological studies on risk estimate of cancer induction in patients exposed earlier when no image intensifiers existed. Diamentor M4 and E meters were used to measure the product dose-area (DAP). The data were acquired during barium enema, barium meal, barium swallow and histerosalpingographies. The measured values of DAP are considered high. This work intends to call the attention toward the optimization of the radiological protection in facilities that still use equipment without image intensifiers. While this equipment cannot be disabled, the patient exposure monitoring should be an incentive, and the application of radiological protection practices and programs of quality assurance should be of priority. (author)

  14. A system and method for imaging body areas

    NARCIS (Netherlands)

    Goethals, F.P.C.

    2013-01-01

    The invention relates to a system for imaging one or more external human body areas comprising a photographic device configured to acquire, store and output an image or images of the one or more body areas. The invention also relates to a method for determining a probable disease state of an externa

  15. Array tomography: semiautomated image alignment.

    Science.gov (United States)

    Micheva, Kristina D; O'Rourke, Nancy; Busse, Brad; Smith, Stephen J

    2010-11-01

    Array tomography is a volumetric microscopy method based on physical serial sectioning. Ultrathin sections of a plastic-embedded tissue are cut using an ultramicrotome, bonded in an ordered array to a glass coverslip, stained as desired, and imaged. The resulting two-dimensional image tiles can then be reconstructed computationally into three-dimensional volume images for visualization and quantitative analysis. The minimal thickness of individual sections permits high-quality rapid staining and imaging, whereas the array format allows reliable and convenient section handling, staining, and automated imaging. Also, the physical stability of the arrays permits images to be acquired and registered from repeated cycles of staining, imaging, and stain elution, as well as from imaging using multiple modalities (e.g., fluorescence and electron microscopy). Array tomography makes it possible to visualize and quantify previously inaccessible features of tissue structure and molecular architecture. However, careful preparation of the tissue is essential for successful array tomography; these steps can be time-consuming and require some practice to perfect. Successful array tomography requires that the captured images be properly stacked and aligned, and the software to achieve these ends is freely available. This protocol describes the construction of volumetric image stacks from images of fluorescently labeled arrays for three-dimensional image visualization, analysis, and archiving. PMID:21041400

  16. Shareholder Rights and the Effects of Acquirer Cash Holdings on Merger Performance

    OpenAIRE

    Ning Gao and Abdulkadir Mohamed

    2015-01-01

    In the U.S., cash-rich acquirers perform better in the presence of strong shareholder rights both at deal announcement and in the long run after mergers. Cash-rich acquirers underperform only when they are less financially constrained and when their shareholders possess weak rights. In the U.K., this positive cash effect on acquirer performance persists on average. In both countries, positive cash holdings effects are stronger when an acquirer is more financially constrained and can be explai...

  17. Magnetic resonance imaging for image-guided implantology

    Science.gov (United States)

    Eggers, Georg; Kress, Bodo; Fiebach, Jochen; Rieker, Marcus; Spitzenberg, Doreen; Marmulla, Rüdiger; Dickhaus, Hartmut; Mühling, Joachim

    2006-03-01

    Image guided implantology using navigation systems is more accurate than manual dental implant insertion. The underlying image data are usually derived from computer tomography. The suitability of MR imaging for dental implant planning is a marginal issue so far. MRI data from cadaver heads were acquired using various MRI sequences. The data were assessed for the quality of anatomical imaging, geometric accuracy and susceptibility to dental metal artefacts. For dental implant planning, 3D models of the jaws were created. A software system for segmentation of the mandible and maxilla MRI data was implemented using c++, mitk, and qt. With the VIBE_15 sequence, image data with high geometric accuracy were acquired. Dental metal artefacts were lower than in CT data of the same heads. The segmentation of the jaws was feasible, in contrast to the segmentation of the dentition, since there is a lack of contrast to the intraoral soft tissue structures. MRI is a suitable method for imaging of the region of mouth and jaws. The geometric accuracy is excellent and the susceptibility to artefacts is low. However, there are yet two limitations: Firstly, the imaging of the dentition needs further improvement to allow accurate segmentation of these regions. Secondly, the sequence used in this study takes several minutes and hence is susceptible to motion artefacts.

  18. White matter microstructural changes as vulnerability factors and acquired signs of post-earthquake distress.

    Directory of Open Access Journals (Sweden)

    Atsushi Sekiguchi

    Full Text Available Many survivors of severe disasters need psychological support, even those not suffering post-traumatic stress disorder (PTSD. The critical issue in understanding the psychological response after experiencing severe disasters is to distinguish neurological microstructural underpinnings as vulnerability factors from signs of emotional distress acquired soon after the stressful life event. We collected diffusion-tensor magnetic resonance imaging (DTI data from a group of healthy adolescents before the Great East Japan Earthquake and re-examined the DTIs and anxiety levels of 30 non-PTSD subjects from this group 3-4 months after the earthquake using voxel-based analyses in a longitudinal DTI study before and after the earthquake. We found that the state anxiety level after the earthquake was negatively associated with fractional anisotropy (FA in the right anterior cingulum (Cg before the earthquake (r = -0.61, voxel level p<0.0025, cluster level p<0.05 corrected, and positively associated with increased FA changes from before to after the earthquake in the left anterior Cg (r = 0.70, voxel level p<0.0025, cluster level p<0.05 corrected and uncinate fasciculus (Uf (r = 0.65, voxel level p<0.0025, cluster level p<0.05 corrected. The results demonstrated that lower FA in the right anterior Cg was a vulnerability factor and increased FA in the left anterior Cg and Uf was an acquired sign of state anxiety after the earthquake. We postulate that subjects with dysfunctions in processing fear and anxiety before the disaster were likely to have higher anxiety levels requiring frequent emotional regulation after the disaster. These findings provide new evidence of psychophysiological responses at the neural network level soon after a stressful life event and might contribute to the development of effective methods to prevent PTSD.

  19. Distortion correction in whole-body imaging of live mice using a 1-Tesla compact magnetic resonance imaging system

    International Nuclear Information System (INIS)

    The aim of this study was to establish a distortion correction applicable to whole-body imaging of live mice. All magnetic resonance imaging (MRI) scans were acquired on a compact 1-T permanent magnet unit for mouse imaging using a T1-weighted, three-dimensional (3D) fast low-angle shot sequence. We assessed geometric distortion in MR images of a small 3D grid phantom and determined 3D image transformations for distortion correction. The developed distortion correction was applied to MR images of the 3D grid phantom acquired on another day, and the correction was validated. A two-dimensional (2D) grid phantom was imaged with a mouse to investigate the applicability of the distortion correction to whole-body mouse imaging. Obvious geometric distortion was observed in the MR images of the 3D grid phantom. The application of the developed 3D phantom-based distortion correction reduced distortion in the images of the 3D grid phantom acquired on another day. Geometric distortion was observed in the MR images of the 2D grid phantom acquired together with the mouse. The 3D phantom-based correction decreased the distortion substantially, regardless of mouse positioning. The developed distortion correction can reduce distortion in whole-body imaging of live mice and may enhance the capabilities of MRI in small animal experiments. (author)

  20. Multispectral analytical image fusion

    International Nuclear Information System (INIS)

    With new and advanced analytical imaging methods emerging, the limits of physical analysis capabilities and furthermore of data acquisition quantities are constantly pushed, claiming high demands to the field of scientific data processing and visualisation. Physical analysis methods like Secondary Ion Mass Spectrometry (SIMS) or Auger Electron Spectroscopy (AES) and others are capable of delivering high-resolution multispectral two-dimensional and three-dimensional image data; usually this multispectral data is available in form of n separate image files with each showing one element or other singular aspect of the sample. There is high need for digital image processing methods enabling the analytical scientist, confronted with such amounts of data routinely, to get rapid insight into the composition of the sample examined, to filter the relevant data and to integrate the information of numerous separate multispectral images to get the complete picture. Sophisticated image processing methods like classification and fusion provide possible solution approaches to this challenge. Classification is a treatment by multivariate statistical means in order to extract analytical information. Image fusion on the other hand denotes a process where images obtained from various sensors or at different moments of time are combined together to provide a more complete picture of a scene or object under investigation. Both techniques are important for the task of information extraction and integration and often one technique depends on the other. Therefore overall aim of this thesis is to evaluate the possibilities of both techniques regarding the task of analytical image processing and to find solutions for the integration and condensation of multispectral analytical image data in order to facilitate the interpretation of the enormous amounts of data routinely acquired by modern physical analysis instruments. (author)