WorldWideScience

Sample records for cc-mgr combined cycle

  1. Oxygen blast furnace and combined cycle (OBF-CC) - an efficient iron-making and power generation process

    International Nuclear Information System (INIS)

    Jianwei, Y.; Guolong, S.; Cunjiang, K.; Tianjun, Y.

    2003-01-01

    A new iron and power generating process, oxygen blast furnace and combined cycle (OBF-CC), is presented. In order to support the opinion, the features of the oxygen blast furnace and integrated coal gasification and combined cycle (IGCC) are summarized. The relation between the blasting parameters and the output gas quantity, as well as caloric value is calculated based on mass and energy balance. Analysis and calculation indicate that the OBF-CC will be an efficient iron-making and power generation process with higher energy efficiency and less pollution

  2. CLASSIFICATION OF THE MGR MUCK HANDLING SYSTEM

    International Nuclear Information System (INIS)

    R. Garrett

    1999-01-01

    The purpose of this analysis is to document the Quality Assurance (QA) classification of the Monitored Geologic Repository (MGR) muck handling system structures, systems and components (SSCs) performed by the MGR Safety Assurance Department. This analysis also provides the basis for revision of YMP/90-55Q, Q-List (YMP 1998). The Q-List identifies those MGR SSCs subject to the requirements of DOE/RW-0333P, ''Quality Assurance Requirements and Description (QARD) (DOE 1998). This QA classification incorporates the current MGR design and the results of the ''Preliminary Preclosure Design Basis Event Calculations for the Monitored Geologic Repository (CRWMS M and O 1998a)

  3. CLASSIFICATION OF THE MGR SITE WATER SYSTEM

    International Nuclear Information System (INIS)

    J.A. Ziegler

    1999-01-01

    The purpose of this analysis is to document the Quality Assurance (QA) classification of the Monitored Geologic Repository (MGR) site water system structures, systems and components (SSCs) performed by the MGR Safety Assurance Department. This analysis also provides the basis for revision of YMP/90-55Q, Q-List (YMP 1998). The Q-List identifies those MGR SSCs subject to the requirements of DOE/RW-0333P, ''Quality Assurance Requirements and Description'' (QARD) (DOE 1998)

  4. Classification of the MGR Assembly Transfer System

    International Nuclear Information System (INIS)

    S.E. Salzman

    1999-01-01

    The purpose of this analysis is to document the Quality Assurance (QA) classification of the Monitored Geologic Repository (MGR) assembly transfer system structures, systems and components (SSCs) performed by the MGR Safety Assurance Department. This analysis also provides the basis for revision of YMP/90-55Q, Q-List (YMP 1998). The Q-List identifies those MGR SSCs subject to the requirements of DOE/RW-0333P, ''Quality Assurance Requirements and Description'' (QARD) (DOE 1998)

  5. CLASSIFICATION OF THE MGR SITE OPERATIONS SYSTEM

    International Nuclear Information System (INIS)

    J.A. Ziegler

    1999-01-01

    The purpose of this analysis is to document the Quality Assurance (QA) classification of the Monitored Geologic Repository (MGR) site operations system structures, systems and components (SSCs) performed by the MGR Safety Assurance Department. This analysis also provides the basis for revision of YMP/90-55Q, Q-List (YMP 1998). The Q-List identifies those MGR SSCs subject to the requirements of DOE/RW-0333P, ''Quality Assurance Requirements and Description'' (QARD) (DOE 1998)

  6. CLASSIFICATION OF THE MGR SITE LAYOUT SYSTEM

    International Nuclear Information System (INIS)

    S.E. Salzman

    1999-01-01

    The purpose of this analysis is to document the Quality Assurance (QA) classification of the Monitored Geologic Repository (MGR) site layout system structures, systems and components (SSCs) performed by the MGR Safety Assurance Department. This analysis also provides the basis for revision of YMP/90-55Q, Q-List (YMP 1998). The Q-List identifies those MGR SSCs subject to the requirements of DOE/RW-0333P, ''Quality Assurance Requirements and Description'' (QARD) (DOE 1998)

  7. CLASSIFICATION OF THE MGR OFFSITE UTILITIES SYSTEM

    International Nuclear Information System (INIS)

    J.A. Ziegler

    1999-01-01

    The purpose of this analysis is to document the Quality Assurance (QA) classification of the Monitored Geologic Repository (MGR) offsite utilities system structures, systems and components (SSCs) performed by the MGR Safety Assurance Department. This analysis also provides the basis for revision of YMP/90-55Q, Q-List (YMP 1998). The Q-List identifies those MGR SSCs subject to the requirements of DOE/RW-0333P, ''Quality Assurance Requirements and Description'' (QARD) (DOE 1998)

  8. CLASSIFICATION OF THE MGR SUBSURFACE EXCAVATION SYSTEM

    International Nuclear Information System (INIS)

    R. Garrett

    1999-01-01

    The purpose of this analysis is to document the Quality Assurance (QA) classification of the Monitored Geologic Repository (MGR) subsurface excavation system structures, systems and components (SSCs) performed by the MGR Safety Assurance Department. This analysis also provides the basis for revision of YMP/90-55Q, Q-List (YMP 1998). The Q-List identifies those MGR SSCs subject to the requirements of DOE/RW-0333P, ''Quality Assurance Requirements and Description'' (QARD) (DOE 1998)

  9. CLASSIFICATION OF THE MGR SUBSURFACE VENTILATION SYSTEM

    International Nuclear Information System (INIS)

    R.J. Garrett

    1999-01-01

    The purpose of this analysis is to document the Quality Assurance (QA) classification of the Monitored Geologic Repository (MGR) subsurface ventilation system structures, systems and components (SSCs) performed by the MGR Safety Assurance Department. This analysis also provides the basis for revision of YMP/90-55Q, Q-List (YMP 1998). The Q-List identifies those MGR SSCs subject to the requirements of DOE/RW-0333P7 ''Quality Assurance Requirements and Description'' (QARD) (DOE 1998)

  10. CLASSIFICATION OF THE MGR EMERGENCY RESPONSE SYSTEM

    International Nuclear Information System (INIS)

    Zeigler, J.A.

    1999-01-01

    The purpose of this analysis is to document the Quality Assurance (QA) classification of the Monitored Geologic Repository (MGR) emergency response system structures, systems and components (SSCs) performed by the MGR Safety Assurance Department. This analysis also provides the basis for revision of YMP/90-55Q, Q-List (YMP 1998). The Q-List identifies those MGR SSCs subject to the requirements of DOE/RW-0333P7 ''Quality Assurance Requirements and Description'' (QARD) (DOE 1998)

  11. CLASSIFICATION OF THE MGR WASTE EMPLACEMENT/RETRIEVAL SYSTEM

    International Nuclear Information System (INIS)

    J.A. Ziegler

    2000-01-01

    The purpose of this analysis is to document the Quality Assurance (QA) classification of the Monitored Geologic Repository (MGR) waste emplacement/retrieved system structures, systems and components (SSCs) performed by the MGR Preclosure Safety and Systems Engineering Section. This analysis also provides the basis for revision of YMP/90-55Q, Q-List (YMP 2000). The Q-List identifies those MGR SSCs subject to the requirements of DOE/RW-0333P, Quality Assurance Requirements and Description (QARD) (DOE 2000). This QA classification incorporates the current MGR design and the results of the ''Design Basis Event Frequency and Dose Calculation for Site Recommendation'' (CRWMS M andO 2000a). The content and technical approach of this analysis is in accordance with the development plan ''QA Classification of MGR Structures, Systems, and Components'' (CRWMS M andO 1999b)

  12. Critical review of the first-law efficiency in different power combined cycle architectures

    International Nuclear Information System (INIS)

    Iglesias Garcia, Steven; Ferreiro Garcia, Ramon; Carbia Carril, Jose; Iglesias Garcia, Denis

    2017-01-01

    Highlights: • The adiabatic expansion based TC can improve the energy efficiency of CCs. • A revolutionary TC can be a starting point to develop high-performance CCs. • A theoretical thermal efficiency of 83.7% was reached in a Nuclear Power Plant using a TC as bottoming cycle. - Abstract: This critical review explores the potential of an innovative trilateral thermodynamic cycle used to transform low-grade heat into mechanical work and compares its performance with relevant traditional thermodynamic cycles in combined cycles. The aim of this work is to show that combined cycles use traditional low efficiency power cycles in their bottoming cycle, and to evaluate theoretically the implementation of alternative power bottoming cycles. Different types of combined cycles have been reviewed, highlighting their relevant characteristics. The efficiencies of power plants using combined cycles are reviewed and compared. The relevance of researching thermodynamic cycles for combined cycle applications is that a vast amount of heat energy is available at negligible cost in the bottoming cycle of a combined cycle, with the drawback that existing thermal cycles cannot make efficient use of such available low temperature heat due to their low efficiency. The first-law efficiency is used as a parameter to compare and suggest improvements in the combined cycles (CCs) reviewed. The analysis shows that trilateral cycles using closed processes are by far the most efficient published thermal cycles for combined cycles to transform low-grade heat into mechanical work. An innovative trilateral bottoming cycle is proposed to show that the application of non-traditional power cycles can increase significantly the first-law efficiency of CCs. The highest first-law efficiencies achieved are: 85.55% in a CC using LNG cool, 73.82% for a transport vehicle CC, 74.40% in a marine CC, 83.07% in a CC for nuclear power plants, 73.82% in a CC using Brayton and Rankine cycles, 78.31% in a CC

  13. CLASSIFICATION OF THE MGR SITE COMPRESSED AIR SYSTEM

    International Nuclear Information System (INIS)

    J.A. Ziegler

    1999-01-01

    The purpose of this analysis is to document the Quality Assurance (QA) classification of the Monitored Geologic Repository (MGR) site compressed air system structures, systems and components (SSCs) performed by the MGR Safety Assurance Department. This analysis also provides the basis for revision of YMP/90-55Q, Q-List (YMP 1998). The Q-List identifies those MGR SSCs subject to the requirements of DOE/RW-0333P, ''Quality Assurance Requirements and Description'' (QARD) (DOE 1998)

  14. CLASSIFICATION OF THE MGR MAINTENANCE AND SUPPLY SYSTEM

    International Nuclear Information System (INIS)

    J.A. Ziegler

    1999-01-01

    The purpose of this analysis is to document the Quality Assurance (QA) classification of the Monitored Geologic Repository (MGR) maintenance and supply system structures, systems and components (SSCs) performed by the MGR Safety Assurance Department. This analysis also provides the basis for revision of YMP/90-55Q, Q-List (YMP 1998). The Q-List identifies those MGR SSCs subject to the requirements of DOE/RW-0333P, ''Quality Assurance Requirements and Description'' (QARD) (DOE 1998)

  15. CLASSIFICATION OF THE MGR WASTE HANDLING BUILDING VENTILATION SYSTEM

    International Nuclear Information System (INIS)

    J.A. Ziegler

    2000-01-01

    The purpose of this analysis is to document the Quality Assurance (QA) classification of the Monitored Geologic Repository (MGR) waste handling building ventilation system structures, systems and components (SSCs) performed by the MGR Preclosure Safety and Systems Engineering Section. This analysis also provides the basis for revision of YMP/90-55Q, Q-List (YMP 2000). The Q-List identifies those MGR SSCs subject to the requirements of DOE/RW-0333P, ''Quality Assurance Requirements and Description'' (QARD) (DOE 2000). This QA classification incorporates the current MGR design and the results of the ''Design Basis Event Frequency and Dose Calculation for Site Recommendation'' (CRWMS M andO 2000a) and ''Bounding Individual Category 1 Design Basis Event Dose Calculation to Support Quality Assurance Classification'' (Gwyn 2000)

  16. CLASSIFICATION OF THE MGR WASTE HANDLING BUILDING ELECTRICAL SYSTEM

    International Nuclear Information System (INIS)

    S.E. Salzman

    1999-01-01

    The purpose of this analysis is to document the Quality Assurance (QA) classification of the Monitored Geologic Repository (MGR) waste handling building electrical system structures, systems and components (SSCs) performed by the MGR Safety Assurance Department. This analysis also provides the basis for revision of YMP/90-55Q, Q-List (YMP 1998). The Q-List identifies those MGR SSCs subject to the requirements of DOE/RW-0333P, ''Quality Assurance Requirements and Description'' (QARD) (DOE 1998)

  17. CLASSIFICATION OF THE MGR OPERATIONS MONITORING AND CONTROL SYSTEM

    International Nuclear Information System (INIS)

    R.J. Garrett

    1999-01-01

    The purpose of this analysis is to document the Quality Assurance (QA) classification of the Monitored Geologic Repository (MGR) Operations Monitoring and Control System structures, systems and components (SSCs) performed by the MGR Safety Assurance Department. This analysis also provides the basis for revision of YMP/90-55Q, Q-List (YMP 1998). The Q-List identifies those MGR SSCs subject to the requirements of DOE/RW-0333P7 ''Quality Assurance Requirements and Description'' (QARD) (DOE 1998)

  18. webMGR: an online tool for the multiple genome rearrangement problem.

    Science.gov (United States)

    Lin, Chi Ho; Zhao, Hao; Lowcay, Sean Harry; Shahab, Atif; Bourque, Guillaume

    2010-02-01

    The algorithm MGR enables the reconstruction of rearrangement phylogenies based on gene or synteny block order in multiple genomes. Although MGR has been successfully applied to study the evolution of different sets of species, its utilization has been hampered by the prohibitive running time for some applications. In the current work, we have designed new heuristics that significantly speed up the tool without compromising its accuracy. Moreover, we have developed a web server (webMGR) that includes elaborate web output to facilitate navigation through the results. webMGR can be accessed via http://www.gis.a-star.edu.sg/~bourque. The source code of the improved standalone version of MGR is also freely available from the web site. Supplementary data are available at Bioinformatics online.

  19. CLASSIFICATION OF THE MGR NON-FUEL COMPONENTS DISPOSAL CONTAINER SYSTEM

    International Nuclear Information System (INIS)

    J.A. Ziegler

    1999-01-01

    The purpose of this analysis is to document the Quality Assurance (QA) classification of the Monitored Geologic Repository (MGR) non-fuel components disposal container system structures, systems and components (SSCs) performed by the MGR Safety Assurance Department. This analysis also provides the basis for revision of YMP/90-55Q, Q-List (YMP 1998). The Q-List identifies those MGR SSCs subject to the requirements of DOE/RW-0333P, ''Quality Assurance Requirements and Description'' (QARD) (DOE 1998)

  20. CLASSIFICATION OF THE MGR PERFORMANCE CONFIRMATION DATA ACQUISITION/MONITORING SYSTEM

    International Nuclear Information System (INIS)

    J.A. Ziegler

    1999-01-01

    The purpose of this analysis is to document the Quality Assurance (QA) classification of the Monitored Geologic Repository (MGR) performance confirmation data acquisition/monitoring system structures, systems and components (SSCs) performed by the MGR Safety Assurance Department. This analysis also provides the basis for revision of YMP/90-55Q, Q-List (YMF 1998). The Q-List identifies those MGR SSCs subject to the requirements of DOE/RW-0333PY ''Quality Assurance Requirements and Description'' (QARD) (DOE 1998)

  1. Thermoeconomic analysis of Biomass Integrated Gasification Gas Turbine Combined Cycle (BIG GT CC) cogeneration plant

    Energy Technology Data Exchange (ETDEWEB)

    Arrieta, Felipe Raul Ponce; Lora, Electo Silva [Escola Federal de Engenharia de Itajuba, MG (Brazil). Nucleo de Estudos de Sistemas Termicos]. E-mails: aponce@iem.efei.br; electo@iem.efei.br; Perez, Silvia Azucena Nebra de [Universidade Estadual de Campinas, SP (Brazil). Faculdade de Engenharia Mecanica. Dept. de Energia]. E-mail: sanebra@fem. unicamp.br

    2000-07-01

    Using thermoeconomics as a tool to identify the location and magnitude of the real thermodynamic losses (energy waste, or exergy destruction and exergy losses) it is possible to assess the production costs of each product (electric power and heat) and the exergetic and exergoeconomic cost of each flow in a cogeneration plant to assist in decision-marketing procedures concerning to plant design, investment, operation and allocations of research funds. Thermo economic analysis of Biomass Integrated Gasification Gas Turbine Combined Cycle (BIG GT CC) cogeneration plant for its applications in sugar cane mills brings the following results: the global exergetic efficiency is low; the highest irreversibilities occur in the following equipment, by order: scrubber (38%), gas turbine (16%), dryer (12%), gasifier and HRSG (6%); due to the adopted cost distribution methodology, the unit exergetic cost of the heat (4,11) is lower than electricity (4,71); the lower market price of biomass is one of the most sensible parameter in the possible implementation of BIG-GT technology in sugar cane industry; the production costs are 31 US$/MWh and 32 US$/MWh for electricity and heat, respectively. The electricity cost is, after all, competitive with the actual market price. The electricity and heat costs are lower or almost equal than other values reported for actual Rankine cycle cogeneration plants. (author)

  2. A Thermodynamic Analysis of Two Competing Mid-Sized Oxyfuel Combustion Combined Cycles

    Directory of Open Access Journals (Sweden)

    Egill Thorbergsson

    2016-01-01

    Full Text Available A comparative analysis of two mid-sized oxyfuel combustion combined cycles is performed. The two cycles are the semiclosed oxyfuel combustion combined cycle (SCOC-CC and the Graz cycle. In addition, a reference cycle was established as the basis for the analysis of the oxyfuel combustion cycles. A parametric study was conducted where the pressure ratio and the turbine entry temperature were varied. The layout and the design of the SCOC-CC are considerably simpler than the Graz cycle while it achieves the same net efficiency as the Graz cycle. The fact that the efficiencies for the two cycles are close to identical differs from previously reported work. Earlier studies have reported around a 3% points advantage in efficiency for the Graz cycle, which is attributed to the use of a second bottoming cycle. This additional feature is omitted to make the two cycles more comparable in terms of complexity. The Graz cycle has substantially lower pressure ratio at the optimum efficiency and has much higher power density for the gas turbine than both the reference cycle and the SCOC-CC.

  3. CLASSIFICATION OF THE MGR DEFENSE HIGH-LEVEL WASTE DISPOSAL CONTAINER SYSTEM

    International Nuclear Information System (INIS)

    J.A. Ziegler

    1999-01-01

    The purpose of this analysis is to document the Quality Assurance (QA) classification of the Monitored Geologic Repository (MGR) defense high-level waste disposal container system structures, systems and components (SSCs) performed by the MGR Safety Assurance Department. This analysis also provides the basis for revision of YMP/90-55Q, Q-List (YMP 1998). The Q-List identifies those MGR SSCs subject to the requirements of DOE/RW-0333PY ''Quality Assurance Requirements and Description'' (QARD) (DOE 1998)

  4. Development of GT-MGR plant power conversion unit design

    International Nuclear Information System (INIS)

    Kostin, V.I.; Kodochigov, N.G.; Belov, S.E.; Vasyaev, A.V.; Golovko, V.F.; Shenoj, A.

    2007-01-01

    The General Atomic Company (USA) and the Pilot Design Bureau for Machine-Building (Russia) are involved in the efforts to design the GT-MGR modular helium cooled reactor and the energy conversion unit with the direct gas turbine cycle. The reactor capacity is equal to 600 MW, it is cooled by helium under 7 MPa pressure. The energy conversion unit consists of a gas turbine, a recuperator, preliminary and intermediate coolers, a generator. The turbine shaft rotation frequency is equal to 4400 rotation/minute. One analyzed the alternate designs of the energy conversion unit to choose its configuration [ru

  5. Posttranslational modification influences the effects of MgrA on norA expression in Staphylococcus aureus.

    Science.gov (United States)

    Truong-Bolduc, Que Chi; Ding, Yanpeng; Hooper, David C

    2008-11-01

    MgrA is a global regulator in Staphylococcus aureus. Differences in the effects of MgrA on norA expression have been reported for different strains, which varied in rsbU, a gene that affects the expression of sigB, which encodes an alternative sigma factor involved in stress responses. We hypothesized that MgrA was modified by sigB-dependent factors that affected its ability to control the expression of the norA efflux pump. Heterologously expressed MgrA purified from Escherichia coli was incubated with crude extracts (CE) from strains RN6390 (rsbU) and SH1000 (rsbU(+)) and tested for binding to the norA promoter. Purified MgrA exhibited greater binding to norA promoter DNA after being incubated with SH1000 CE than MgrA incubated with the RN6390 CE. Phosphorylation of MgrA occurring in cell extracts caused it to lose the ability to bind norA promoter DNA. Overexpression of pknB, encoding a candidate serine/threonine kinase, produced increased phospho-MgrA and led to a fivefold increase in the transcript level of norA for both RN6390 and SH1000, as well as a fourfold increase in the MICs of norfloxacin and ciprofloxacin for these two strains. The levels of expression of pknB in RN6390 and SH1000, however, indicated that additional factors related to rsbU or sigB contribute to the differential regulatory effects of MgrA on norA expression.

  6. PRELIMINARY SELECTION OF MGR DESIGN BASIS EVENTS

    International Nuclear Information System (INIS)

    Kappes, J.A.

    1999-01-01

    The purpose of this analysis is to identify the preliminary design basis events (DBEs) for consideration in the design of the Monitored Geologic Repository (MGR). For external events and natural phenomena (e.g., earthquake), the objective is to identify those initiating events that the MGR will be designed to withstand. Design criteria will ensure that radiological release scenarios resulting from these initiating events are beyond design basis (i.e., have a scenario frequency less than once per million years). For internal (i.e., human-induced and random equipment failures) events, the objective is to identify credible event sequences that result in bounding radiological releases. These sequences will be used to establish the design basis criteria for MGR structures, systems, and components (SSCs) design basis criteria in order to prevent or mitigate radiological releases. The safety strategy presented in this analysis for preventing or mitigating DBEs is based on the preclosure safety strategy outlined in ''Strategy to Mitigate Preclosure Offsite Exposure'' (CRWMS M andO 1998f). DBE analysis is necessary to provide feedback and requirements to the design process, and also to demonstrate compliance with proposed 10 CFR 63 (Dyer 1999b) requirements. DBE analysis is also required to identify and classify the SSCs that are important to safety (ITS)

  7. The Staphylococcus aureus Global Regulator MgrA Modulates Clumping and Virulence by Controlling Surface Protein Expression.

    Directory of Open Access Journals (Sweden)

    Heidi A Crosby

    2016-05-01

    Full Text Available Staphylococcus aureus is a human commensal and opportunistic pathogen that causes devastating infections in a wide range of locations within the body. One of the defining characteristics of S. aureus is its ability to form clumps in the presence of soluble fibrinogen, which likely has a protective benefit and facilitates adhesion to host tissue. We have previously shown that the ArlRS two-component regulatory system controls clumping, in part by repressing production of the large surface protein Ebh. In this work we show that ArlRS does not directly regulate Ebh, but instead ArlRS activates expression of the global regulator MgrA. Strains lacking mgrA fail to clump in the presence of fibrinogen, and clumping can be restored to an arlRS mutant by overexpressing either arlRS or mgrA, indicating that ArlRS and MgrA constitute a regulatory pathway. We used RNA-seq to show that MgrA represses ebh, as well as seven cell wall-associated proteins (SraP, Spa, FnbB, SasG, SasC, FmtB, and SdrD. EMSA analysis showed that MgrA directly represses expression of ebh and sraP. Clumping can be restored to an mgrA mutant by deleting the genes for Ebh, SraP and SasG, suggesting that increased expression of these proteins blocks clumping by steric hindrance. We show that mgrA mutants are less virulent in a rabbit model of endocarditis, and virulence can be partially restored by deleting the genes for the surface proteins ebh, sraP, and sasG. While mgrA mutants are unable to clump, they are known to have enhanced biofilm capacity. We demonstrate that this increase in biofilm formation is partially due to up-regulation of SasG, a surface protein known to promote intercellular interactions. These results confirm that ArlRS and MgrA constitute a regulatory cascade, and that they control expression of a number of genes important for virulence, including those for eight large surface proteins.

  8. HTR-Based Power Plants’ Performance Analysis Applied on Conventional Combined Cycles

    Directory of Open Access Journals (Sweden)

    José Carbia Carril

    2015-01-01

    Full Text Available In high temperature reactors including gas cooled fast reactors and gas turbine modular helium reactors (GT-MHR specifically designed to operate as power plant heat sources, efficiency enhancement at effective cost under safe conditions can be achieved. Mentioned improvements concern the implementation of two cycle structures: (a, a stand alone Brayton operating with helium and a stand alone Rankine cycle (RC with regeneration, operating with carbon dioxide at ultrasupercritical pressure as working fluid (WF, where condensation is carried out at quasicritical conditions, and (b, a combined cycle (CC, in which the topping closed Brayton cycle (CBC operates with helium as WF, while the bottoming RC is operated with one of the following WFs: carbon dioxide, xenon, ethane, ammonia, or water. In both cases, an intermediate heat exchanger (IHE is proposed to provide thermal energy to the closed Brayton or to the Rankine cycles. The results of the case study show that the thermal efficiency, through the use of a CC, is slightly improved (from 45.79% for BC and from 50.17% for RC to 53.63 for the proposed CC with He-H2O operating under safety standards.

  9. Phosphorylation of MgrA and its effect on expression of the NorA and NorB efflux pumps of Staphylococcus aureus.

    Science.gov (United States)

    Truong-Bolduc, Que Chi; Hooper, David C

    2010-05-01

    MgrA is a global regulator in Staphylococcus aureus that controls the expression of diverse genes encoding virulence factors and multidrug resistance (MDR) efflux transporters. We identified pknB, which encodes the (Ser/Thr) kinase PknB, in the S. aureus genome. PknB was able to autophosphorylate as well as phosphorylate purified MgrA. We demonstrated that rsbU, which encodes a Ser/Thr phosphatase and is involved in the activation of the SigB regulon, was able to dephosphorylate MgrA-P but not PknB-P. Serines 110 and 113 of MgrA were found to be phosphorylated, and Ala substitutions at these positions resulted in reductions in the level of phosphorylation of MgrA. DNA gel shift binding assays using norA and norB promoters showed that MgrA-P was able to bind the norB promoter but not the norA promoter, a pattern which was the reverse of that for unphosphorylated MgrA. The double mutant MgrA(S110A-S113A) bound to the norA promoter but not the norB promoter. The double mutant led to a 2-fold decrease in norA transcripts and a 2-fold decrease in the MICs of norfloxacin and ciprofloxacin in strain RN6390. Thus, phosphorylation of MgrA results in loss of binding to the norA promoter, but with a gain of the ability to bind the norB promoter. Loss of the ability to phosphorylate MgrA by Ala substitution resulted in increased repression of norA expression and in reductions in susceptibilities to NorA substrates.

  10. Comparison of clinical outcome and costs with CC + gonadotropins and gnrha + gonadotropins during Ivf/ICSI cycles.

    Science.gov (United States)

    Kovacs, Peter; Matyas, Szabolcs; Bernard, l Artur; Kaali, Steven G

    2004-06-01

    To compare clinical outcome and costs of CC + gonadotropins with GnRHa + gonadotropins during IVF/ICSI cycles. Clinical outcome and expenses of 382 CC + gonadotropin and 964 GnRHa + gonadotropin cycles were compared. Medication costs were calculated on the basis of the mean number of ampoules and the proportion of various gonadotropins. Costs per clinical pregnancy were calculated on the basis of expenses and clinical pregnancy rates. Women in the CC + gonadotropin group were younger, and had fewer follicles, oocytes, embryos, and embryos transferred. Clinical pregnancy rates were higher in the GnRHa group (35.9 % vs 26.2%, p costs per cycle were higher in the GnRHa group (US dollars 357 vs 248). Expenses per pregnancy however were lower in the GnRHa group (USdollars 4197 vs 5335 with IVF; USdollars 5590 vs 7244 with ICSI). When different age subgroups with similar baseline characteristics and stimulation parameters were compared, pregnancy rates were significantly higher in the GnRHa groups. Medication cost per cycle was higher in the GnRHa subgroups, and the expense per pregnancy was lower with GnRHa protocol. Cost per cycle is higher with GnRHa + gonadotropin. However, because of the better performance of the GnRHa + gonadotropin stimulation, the cumulative costs are reduced by the time a clinical pregnancy is achieved.

  11. MONITORED GEOLOGIC REPOSITORY LIFE CYCLE COST ESTIMATE ASSUMPTIONS DOCUMENT

    International Nuclear Information System (INIS)

    R.E. Sweeney

    2001-01-01

    The purpose of this assumptions document is to provide general scope, strategy, technical basis, schedule and cost assumptions for the Monitored Geologic Repository (MGR) life cycle cost (LCC) estimate and schedule update incorporating information from the Viability Assessment (VA) , License Application Design Selection (LADS), 1999 Update to the Total System Life Cycle Cost (TSLCC) estimate and from other related and updated information. This document is intended to generally follow the assumptions outlined in the previous MGR cost estimates and as further prescribed by DOE guidance

  12. Monitored Geologic Repository Life Cycle Cost Estimate Assumptions Document

    International Nuclear Information System (INIS)

    Sweeney, R.

    2000-01-01

    The purpose of this assumptions document is to provide general scope, strategy, technical basis, schedule and cost assumptions for the Monitored Geologic Repository (MGR) life cycle cost estimate and schedule update incorporating information from the Viability Assessment (VA), License Application Design Selection (LADS), 1999 Update to the Total System Life Cycle Cost (TSLCC) estimate and from other related and updated information. This document is intended to generally follow the assumptions outlined in the previous MGR cost estimates and as further prescribed by DOE guidance

  13. Gold(I) Complexes with N-Donor Ligands. 2.(1) Reactions of Ammonium Salts with [Au(acac-kappaC(2))(PR(3))] To Give [Au(NH(3))L](+), [(AuL)(2)(&mgr;(2)-NH(2))](+), [(AuL)(4)(&mgr;(4)-N)](+), or [(AuL)(3)(&mgr;(3)-O)](+). A New and Facile Synthesis of [Au(NH(3))(2)](+) Salts. Crystal Structure of [{AuP(C(6)H(4)OMe-4)(3)}(3)(&mgr;(3)-O)]CF(3)SO(3).

    Science.gov (United States)

    Vicente, José; Chicote, María-Teresa; Guerrero, Rita; Jones, Peter G.; Ramírez De Arellano, M. Carmen

    1997-09-24

    The complexes [Au(acac-kappaC(2))(PR(3))] (acac = acetylacetonate, R = Ph, C(6)H(4)OMe-4) react with (NH(4))ClO(4) to give amminegold(I), [Au(NH(3))(PR(3))]ClO(4), amidogold(I), [(AuPR(3))(2)(&mgr;(2)-NH(2))]ClO(4), or nitridogold(I), [(AuPR(3))(4)(&mgr;(4)-N)]ClO(4), complexes, depending on the reaction conditions. Similarly, [Au(acac-kappaC(2))(PPh(3))] reacts with (NH(3)R')OTf (OTf = CF(3)SO(3)) (1:1) or with [H(3)N(CH(2))(2)NH(2)]OTf (1:1) to give (amine)gold(I) complexes [Au(NH(2)R')(PPh(3))]OTf (R' = Me, C(6)H(4)NO(2)-4) or [(AuPPh(3))(2){&mgr;(2)-H(2)N(CH(2))(2)NH(2)}](OTf)(2), respectively. The ammonium salts (NH(2)R'(2))OTf (R' = Et, Ph) react with [Au(acac-kappaC(2))(PR(3))] (R = Ph, C(6)H(4)OMe-4) (1:2) to give, after hydrolysis, the oxonium salts [(AuPR(3))(3)(&mgr;(3)-O)]OTf (R = Ph, C(6)H(4)OMe-4). When NH(3) is bubbled through a solution of [AuCl(tht)] (tht = tetrahydrothiophene), the complex [Au(NH(3))(2)]Cl precipitates. Addition of [Au(NH(3))(2)]Cl to a solution of AgClO(4) or TlOTf leads to the isolation of [Au(NH(3))(2)]ClO(4) or [Au(NH(3))(2)]OTf, respectively. The crystal structure of [(AuPR(3))(3)(&mgr;(3)-O)]OTf.Me(2)CO (R = C(6)H(4)OMe-4) has been determined: triclinic, space group P&onemacr;, a = 14.884(3) Å, b = 15.828(3) Å, c = 16.061(3) Å, alpha = 83.39(3) degrees, beta = 86.28(3) degrees, gamma = 65.54(3) degrees, R1 (wR2) = 0.0370 (0.0788). The [(AuPR(3))(3)(&mgr;(3)-O)](+) cation shows an essentially trigonal pyramidal array of three gold atoms and one oxygen atom with O-Au-P bond angles of ca. 175 degrees and Au.Au contacts in the range 2.9585(7)-3.0505(14) Å. These cations are linked into centrosymmetric dimers through two short Au.Au [2.9585(7), 3.0919(9) Å] contacts. The gold atoms of the dimer form a six-membered ring with a chair conformation.

  14. MGR COMPLIANCE PROGRAM GUIDANCE PACKAGE FOR RADIATION PROTECTION EQUIPMENT, INSTRUMENTATION, AND FACILITIES

    International Nuclear Information System (INIS)

    2000-01-01

    This Compliance Program Guidance Package identifies the regulatory guidance and industry codes and standards addressing radiation protection equipment, instrumentation, and support facilities considered to be appropriate for radiation protection at the Monitored Geologic Repository (MGR). Included are considerations relevant to radiation monitoring instruments, calibration, contamination control and decontamination, respiratory protection equipment, and general radiation protection facilities. The scope of this Guidance Package does not include design guidance relevant to criticality monitoring, area radiation monitoring, effluent monitoring, and airborne radioactivity monitoring systems since they are considered to be the topics of specific design and construction requirements (i.e., ''fixed'' or ''built-in'' systems). This Guidance Package does not address radiation protection design issues; it addresses the selection and calibration of radiation monitoring instrumentation to the extent that the guidance is relevant to the operational radiation protection program. Radon and radon progeny monitoring instrumentation is not included in the Guidance Package since such naturally occurring radioactive materials do not fall within the NRC's jurisdiction at the MGR

  15. MGR External Events Hazards Analysis

    International Nuclear Information System (INIS)

    Booth, L.

    1999-01-01

    The purpose and objective of this analysis is to apply an external events Hazards Analysis (HA) to the License Application Design Selection Enhanced Design Alternative 11 [(LADS EDA II design (Reference 8.32))]. The output of the HA is called a Hazards List (HL). This analysis supersedes the external hazards portion of Rev. 00 of the PHA (Reference 8.1). The PHA for internal events will also be updated to the LADS EDA II design but under a separate analysis. Like the PHA methodology, the HA methodology provides a systematic method to identify potential hazards during the 100-year Monitored Geologic Repository (MGR) operating period updated to reflect the EDA II design. The resulting events on the HL are candidates that may have potential radiological consequences as determined during Design Basis Events (DBEs) analyses. Therefore, the HL that results from this analysis will undergo further screening and analysis based on the criteria that apply during the performance of DBE analyses

  16. Alternative ORC bottoming cycles FOR combined cycle power plants

    International Nuclear Information System (INIS)

    Chacartegui, R.; Sanchez, D.; Munoz, J.M.; Sanchez, T.

    2009-01-01

    In this work, low temperature Organic Rankine Cycles are studied as bottoming cycle in medium and large scale combined cycle power plants. The analysis aims to show the interest of using these alternative cycles with high efficiency heavy duty gas turbines, for example recuperative gas turbines with lower gas turbine exhaust temperatures than in conventional combined cycle gas turbines. The following organic fluids have been considered: R113, R245, isobutene, toluene, cyclohexane and isopentane. Competitive results have been obtained for toluene and cyclohexane ORC combined cycles, with reasonably high global efficiencies. The paper is structured in four main parts. A review of combined cycle and ORC cycle technologies is presented, followed by a thermodynamic analysis of combined cycles with commercial gas turbines and ORC low temperature bottoming cycles. Then, a parametric optimization of an ORC combined cycle plant is performed in order to achieve a better integration between these two technologies. Finally, some economic considerations related to the use of ORC in combined cycles are discussed.

  17. Optimum gas turbine cycle for combined cycle power plant

    International Nuclear Information System (INIS)

    Polyzakis, A.L.; Koroneos, C.; Xydis, G.

    2008-01-01

    The gas turbine based power plant is characterized by its relatively low capital cost compared with the steam power plant. It has environmental advantages and short construction lead time. However, conventional industrial engines have lower efficiencies, especially at part load. One of the technologies adopted nowadays for efficiency improvement is the 'combined cycle'. The combined cycle technology is now well established and offers superior efficiency to any of the competing gas turbine based systems that are likely to be available in the medium term for large scale power generation applications. This paper has as objective the optimization of a combined cycle power plant describing and comparing four different gas turbine cycles: simple cycle, intercooled cycle, reheated cycle and intercooled and reheated cycle. The proposed combined cycle plant would produce 300 MW of power (200 MW from the gas turbine and 100 MW from the steam turbine). The results showed that the reheated gas turbine is the most desirable overall, mainly because of its high turbine exhaust gas temperature and resulting high thermal efficiency of the bottoming steam cycle. The optimal gas turbine (GT) cycle will lead to a more efficient combined cycle power plant (CCPP), and this will result in great savings. The initial approach adopted is to investigate independently the four theoretically possible configurations of the gas plant. On the basis of combining these with a single pressure Rankine cycle, the optimum gas scheme is found. Once the gas turbine is selected, the next step is to investigate the impact of the steam cycle design and parameters on the overall performance of the plant, in order to choose the combined cycle offering the best fit with the objectives of the work as depicted above. Each alterative cycle was studied, aiming to find the best option from the standpoint of overall efficiency, installation and operational costs, maintainability and reliability for a combined power

  18. Neutronic Analysis of the RSG-GAS Compact Core without CIP Silicide 3.55 g U/cc and 4.8 g U/cc

    International Nuclear Information System (INIS)

    Jati S; Lily S; Tukiran S

    2004-01-01

    Fuel conversion from U 3 O 8 -Al to U 3 Si 2 -Al 2.96 g U/cc density in the RSG-GAS core had done successfully step by step since 36 th core until 44 th core. So that, since the 45 th core until now (48 th core) had been using full of silicide 2.96 g U/cc. Even though utilization program of silicide fuel with high density (3.55 g U/cc and 4.8 g U/cc) and optimize operation of RSG-GAS core under research. Optimalitation of core with increasing operation cycle have been analyzing about compact core. The mean of compact core is the RSG-GAS core with decrease number of IP or CIP position irradiation. In this research, the neutronic calculation to cover RSG-GAS core and RSG-GAS core without CIP that are using U 3 Si 2 -Al 2.96 g U/cc, 3.55 g U/cc and 4.8 g U/cc had done. Two core calculation done at 15 MW power using SRAC-ASMBURN code. The calculation result show that fuel conversion from 2.96 g U/cc density to 3.55 g U/cc and 4.8 g U/cc will increasing cycle length for both RSG-GAS core and RSG-GAS compact core without CIP. However, increasing of excess reactivity exceeded from nominal value of first design that 9.2%. Change of power peaking factor is not show significant value and still less than 1.4. Core fuelled with U 3 Si 2 -Al 4.8 g U/cc density have maximum discharge burn-up which exceeded from licensing value (70%). RSG-GAS compact core without CIP fuelled U 3 Si 2 -Al 2.96 g U/cc have longer cycle operation then RSG-GAS core and fulfil limitation neutronic parameter at the first design value. (author)

  19. Thermodynamic efficiency analysis and cycle optimization of deeply precooled combined cycle engine in the air-breathing mode

    Science.gov (United States)

    Zhang, Jianqiang; Wang, Zhenguo; Li, Qinglian

    2017-09-01

    The efficiency calculation and cycle optimization were carried out for the Synergistic Air-Breathing Rocket Engine (SABRE) with deeply precooled combined cycle. A component-level model was developed for the engine, and exergy efficiency analysis based on the model was carried out. The methods to improve cycle efficiency have been proposed. The results indicate cycle efficiency of SABRE is between 29.7% and 41.7% along the flight trajectory, and most of the wasted exergy is occupied by the unburned hydrogen in exit gas. Exergy loss exists in each engine component, and the sum losses of main combustion chamber(CC), pre-burner(PB), precooler(PC) and 3# heat exchanger(HX3) are greater than 71.3% of the total loss. Equivalence ratio is the main influencing factor of cycle, and it can be regulated by adjusting parameters of helium loop. Increase the maximum helium outlet temperature of PC by 50 K, the total assumption of hydrogen will be saved by 4.8%, and the cycle efficiency is advanced by 3% averagely in the trajectory. Helium recirculation scheme introduces a helium recirculation loop to increase local helium flow rate of PC. It turns out the total assumption of hydrogen will be saved by 9%, that's about 1740 kg, and the cycle efficiency is advanced by 5.6% averagely.

  20. Effect of Promoter Region Mutations and mgrA Overexpression on Transcription of norA, Which Encodes a Staphylococcus aureus Multidrug Efflux Transporter

    OpenAIRE

    Kaatz, Glenn W.; Thyagarajan, Rama V.; Seo, Susan M.

    2005-01-01

    NorA is a Staphylococcus aureus multidrug transporter that confers resistance to structurally distinct compounds. The MgrA global regulatory protein is reported to augment norA expression when mgrA is overexpressed from an undefined plasmid-based promoter. Further details about norA regulatory mechanisms are scant. A chromosomal norA::lacZ transcriptional fusion was constructed in different S. aureus strains, and allele replacement was used to define the relevance of promoter region sequences...

  1. Exergetic Analysis of a Novel Solar Cooling System for Combined Cycle Power Plants

    Directory of Open Access Journals (Sweden)

    Francesco Calise

    2016-09-01

    Full Text Available This paper presents a detailed exergetic analysis of a novel high-temperature Solar Assisted Combined Cycle (SACC power plant. The system includes a solar field consisting of innovative high-temperature flat plate evacuated solar thermal collectors, a double stage LiBr-H2O absorption chiller, pumps, heat exchangers, storage tanks, mixers, diverters, controllers and a simple single-pressure Combined Cycle (CC power plant. Here, a high temperature solar cooling system is coupled with a conventional combined cycle, in order to pre-cool gas turbine inlet air in order to enhance system efficiency and electrical capacity. In this paper, the system is analyzed from an exergetic point of view, on the basis of an energy-economic model presented in a recent work, where the obtained main results show that SACC exhibits a higher electrical production and efficiency with respect to the conventional CC. The system performance is evaluated by a dynamic simulation, where detailed simulation models are implemented for all the components included in the system. In addition, for all the components and for the system as whole, energy and exergy balances are implemented in order to calculate the magnitude of the irreversibilities within the system. In fact, exergy analysis is used in order to assess: exergy destructions and exergetic efficiencies. Such parameters are used in order to evaluate the magnitude of the irreversibilities in the system and to identify the sources of such irreversibilities. Exergetic efficiencies and exergy destructions are dynamically calculated for the 1-year operation of the system. Similarly, exergetic results are also integrated on weekly and yearly bases in order to evaluate the corresponding irreversibilities. The results showed that the components of the Joule cycle (combustor, turbine and compressor are the major sources of irreversibilities. System overall exergetic efficiency was around 48%. Average weekly solar collector

  2. Economic competitiveness of small modular reactors versus coal and combined cycle plants

    International Nuclear Information System (INIS)

    Alonso, Gustavo; Bilbao, Sama; Valle, Edmundo del

    2016-01-01

    Small modular reactors (SMRs) may be an option to cover the electricity needs of isolated regions, distributed generation grids and countries with small electrical grids. Previous analyses show that the overnight capital cost for SMRs is between 4500 US$/kW and 5350 US$/kW, which is between a 6% and a 26% higher than the average cost of a current large nuclear reactor. This study analyzes the economic competitiveness of small modular reactors against thermal plants using coal and natural gas combined cycle plants. To assess the economic competitiveness of SMRs, three overnight capital costs are considered 4500 US$/kW, 5000 US$/kW and 5350 US$/kW along with three discount rates for each overnight cost considered, these are 3, 7, and 10%. To compare with natural gas combined cycle (CC) units, four different gas prices are considered, these are 4.74 US$/GJ (5 US$/mmBTU), 9.48 US$/GJ (10 US$/mmBTU), 14.22 US$/GJ (15 US$/mmBTU), and 18.96 US$/GJ (20 US$/mmBTU). To compare against coal, two different coal prices are considered 80 and 120 US$/ton of coal. The carbon tax considered, for both CC and coal, is 30 US$/ton CO_2. The results show what scenarios make SMRs competitive against coal and/or combined cycle plants. In addition, because the price of electricity is a key component to guarantee the feasibility of a new project, this analysis calculates the price of electricity for the economically viable deployment of SMRs in all the above scenarios. In particular, this study shows that a minimum price of electricity of 175 US$/MWh is needed to guarantee the feasibility of a new SMR, if its overnight capital cost is 5350 US$/kWe and the discount rate is 10%. Another result is that when the price of electricity is around 100 US$/MWh then the discount rate must be around 7% or less to provide appropriate financial conditions to make SMRs economically feasible. - Highlights: • Small modular reactor (SMR) are economically assessed. • SMR are compared against gas and coal

  3. RADIATION ACCESS ZONE AND VENTILATION CONFINEMENT ZONE CRITERIA FOR THE MGR SURFACE FACILITIES

    International Nuclear Information System (INIS)

    D. A. Padula

    2000-01-01

    The objectives of this technical report are to: (1) Establish the criteria for Radiation Access Zone (RAZ) designation. (2) Establish the criteria for the Ventilation Confinement Zone (VCZ) designation. The scope will be to formulate the RAZ and VCZ zoning designation for the Monitored Geologic Repository (MGR) surface facilities and to apply the zoning designations to the current Waste Handling Building (WHB), Waste Treatment Building (WTB), and Carrier Preparation Building (CPB) configurations

  4. High performance integrated solar combined cycles with minimum modifications to the combined cycle power plant design

    International Nuclear Information System (INIS)

    Manente, Giovanni

    2016-01-01

    Highlights: • Off-design model of a 390 MW_e three pressure combined cycle developed and validated. • The off-design model is used to evaluate different hybridization schemes with solar. • Power boosting and fuel saving with different design modifications are considered. • Maximum solar share of total electricity is only 1% with the existing equipment. • The maximum incremental solar radiation-to-electrical efficiency approaches 29%. - Abstract: The integration of solar energy into natural gas combined cycles has been successfully demonstrated in several integrated solar combined cycles since the beginning of this decade in many countries. There are many motivations that drive investments on integrated solar combined cycles which are primarily the repowering of existing power plants, the compliance with more severe environmental laws on emissions and the mitigation of risks associated with large solar projects. Integrated solar combined cycles are usually developed as brownfield facilities by retrofitting existing natural gas combined cycles and keeping the existing equipment to minimize costs. In this work a detailed off-design model of a 390 MW_e three pressure level natural gas combined cycle is built to evaluate different integration schemes of solar energy which either keep the equipment of the combined cycle unchanged or include new equipment (steam turbine, heat recovery steam generator). Both power boosting and fuel saving operation strategies are analyzed in the search for the highest annual efficiency and solar share. Results show that the maximum incremental power output from solar at design solar irradiance is limited to 19 MW_e without modifications to the existing equipment. Higher values are attainable only including a larger steam turbine. High solar radiation-to-electrical efficiencies in the range 24–29% can be achieved in the integrated solar combined cycle depending on solar share and extension of tube banks in the heat recovery

  5. Variable geometry gas turbines for improving the part-load performance of marine combined cycles - Combined cycle performance

    DEFF Research Database (Denmark)

    Haglind, Fredrik

    2011-01-01

    The part-load performance of combined cycles intended for naval use is of great importance, and it is influenced by the gas turbine configuration and load control strategy. This paper is aimed at quantifying the effects of variable geometry gas turbines on the part-load efficiency for combined...... cycles used for ship propulsion. Moreover, the paper is aimed at developing methodologies and deriving models for part-load simulations suitable for energy system analysis of various components within combined cycle power plants. Two different gas turbine configurations are studied, a two-shaft aero......-derivative configuration and a single-shaft industrial configuration. The results suggest that by the use of variable geometry gas turbines, the combined cycle part-load performance can be improved. In order to minimise the voyage fuel consumption, a combined cycle featuring two-shaft gas turbines with VAN control...

  6. Bifuel coal-gas combined cycles

    International Nuclear Information System (INIS)

    Chmielniak, Tadeusz; Kotowicz, Janusz; Lyczko, Jacek

    1997-01-01

    This paper describes basic ways of realization of bi fuel cool-gas combined cycles. The criterion of classification of the systems specification is a joint of the gas pail with the steam part: a) The gas turbine flue gases are introduced into the steam boiler combustion chamber (the serial, hot wind box). b) Bypass of the beat exchangers at the steam turbine unit and/or the steam boiler, by use the waste heat exchangers, or waste boiler at the gas turbine unit (the parallel-coupled). c) The mixed, it's a combination of the two upper. The analysis of the parallel system has been specially presented. In derived formulas for the total efficiency of the bi fuel parallel combined cycle balance equations have been used. This formulas can be used for planning new combined cycle power plants and for modernization existing steam power plants. It was made a discussion about influence of the ratio the gas and the steam turbine electric power on the cycle efficiency in care of the full and the part load of the bi fuel combined cycle power plant. The various systems of the joint of the gas part with the steam part have been examined. The selected results of the calculations have been attached. The models and the numerical simulations have been based on data from the existing steam power plants and real gas turbine units. (Author)

  7. Thermal fatigue behavior of C/C composites modified by SiC-MoSi2-CrSi2 coating

    International Nuclear Information System (INIS)

    Chu Yanhui; Fu Qiangang; Li Hejun; Li Kezhi

    2011-01-01

    Highlights: → The low-density C/C composites were modified by SiC-MoSi 2 -CrSi 2 multiphase coating by pack cementation. → The thermal fatigue behavior of the modified C/C composites was studied after undergoing thermal cycling for 20 times under the different environments. → The decrease of the flexural strength of the modified C/C composites during thermal cycle in air was primarily attributed to the partial oxidation of the modified C/C samples. - Abstract: Carbon/carbon (C/C) composites were modified by SiC-MoSi 2 -CrSi 2 multiphase coating by pack cementation, and their thermal fatigue behavior under thermal cycling in Ar and air environments was investigated. The modified C/C composites were characterized by scanning electron microscopy and X-ray diffraction. Results of tests show that, after 20-time thermal cycles between 1773 K and room temperature in Ar environment, the flexural strength of modified C/C samples decreased lightly and the percentage of remaining strength was 94.92%. While, after thermal cycling between 1773 K and room temperature in air for 20 times, the weight loss of modified C/C samples was 5.1%, and the flexural strength of the modified C/C samples reduced obviously and the percentage of remaining strength was only 75.22%. The fracture mode of modified C/C samples changed from a brittle behavior to a pseudo-plastic one as the service environment transformed from Ar to air. The decrease of the flexural strength during thermal cycle in air was primarily attributed to the partial oxidation of modified C/C samples.

  8. Studies of a Combined-Cycle Engine

    OpenAIRE

    苅田, 丈士; KANDA, Takeshi

    2003-01-01

    For a Single-Stage-to-Orbit (SSTO) aerospace plane (Fig.1), several engines will be necessary to reach orbit. The combined-cycle engine incorporates several operational modes in a single engine. Study of the combined cycle engine has a long history, and several kinds of such engines have been proposed and studied. When several engines are mounted on a vehicle, each engine of the system will show a performance higher than that of the combined cycle engine. However, during the operation of one ...

  9. Pharmacokinetics and Pharmacodynamics with Extended Dosing of CC-486 in Patients with Hematologic Malignancies.

    Directory of Open Access Journals (Sweden)

    Eric Laille

    Full Text Available CC-486 (oral azacitidine is an epigenetic modifier in development for patients with myelodysplastic syndromes and acute myeloid leukemia. In part 1 of this two-part study, a 7-day CC-486 dosing schedule showed clinical activity, was generally well tolerated, and reduced DNA methylation. Extending dosing of CC-486 beyond 7 days would increase duration of azacitidine exposure. We hypothesized that extended dosing would therefore provide more sustained epigenetic activity. Reported here are the pharmacokinetic (PK and pharmacodynamic (PD profiles of CC-486 extended dosing schedules in patients with myelodysplastic syndromes (MDS, chronic myelomonocytic leukemia (CMML or acute myeloid leukemia (AML from part 2 of this study. PK and/or PD data were available for 59 patients who were sequentially assigned to 1 of 4 extended CC-486 dosing schedules: 300mg once-daily or 200mg twice-daily for 14 or 21 days per 28-day cycle. Both 300mg once-daily schedules and the 200mg twice-daily 21-day schedule significantly (all P < .05 reduced global DNA methylation in whole blood at all measured time points (days 15, 22, and 28 of the treatment cycle, with sustained hypomethylation at cycle end compared with baseline. CC-486 exposures and reduced DNA methylation were significantly correlated. Patients who had a hematologic response had significantly greater methylation reductions than non-responding patients. These data demonstrate that extended dosing of CC-486 sustains epigenetic effects through the treatment cycle.ClinicalTrials.gov NCT00528983.

  10. Combined-cycle plants

    International Nuclear Information System (INIS)

    Valenti, M.

    1991-01-01

    This paper reports that as tougher emissions standards take hold throughout the industrialized world, manufacturers such as GE, Siemens, Foster Wheeler, and Asea Brown Boveri are designing advanced combined-cycle equipment that offers improved environmental performance without sacrificing power efficiency

  11. Gas--steam turbine combined cycle power plants

    Energy Technology Data Exchange (ETDEWEB)

    Christian, J.E.

    1978-10-01

    The purpose of this technology evaluation is to provide performance and cost characteristics of the combined gas and steam turbine, cycle system applied to an Integrated Community Energy System (ICES). To date, most of the applications of combined cycles have been for electric power generation only. The basic gas--steam turbine combined cycle consists of: (1) a gas turbine-generator set, (2) a waste-heat recovery boiler in the gas turbine exhaust stream designed to produce steam, and (3) a steam turbine acting as a bottoming cycle. Because modification of the standard steam portion of the combined cycle would be necessary to recover waste heat at a useful temperature (> 212/sup 0/F), some sacrifice in the potential conversion efficiency is necessary at this temperature. The total energy efficiency ((electric power + recovered waste heat) divided by input fuel energy) varies from about 65 to 73% at full load to 34 to 49% at 20% rated electric power output. Two major factors that must be considered when installing a gas--steam turbine combines cycle are: the realiability of the gas turbine portion of the cycle, and the availability of liquid and gas fuels or the feasibility of hooking up with a coal gasification/liquefaction process.

  12. Hybrid Combined Cycles with Biomass and Waste Fired Bottoming Cycle - a Literature Study

    Energy Technology Data Exchange (ETDEWEB)

    Petrov, Miroslav P.

    2002-02-01

    Biomass is one of the main natural resources in Sweden. The present low-CO{sub 2} emission characteristics of the Swedish electricity production system (hydro and nuclear) can be retained only by expansion of biofuel applications for energy purposes. Domestic Swedish biomass resources are vast and renewable, but not infinite. They must be utilized as efficiently as possible, in order to make sure that they meet the conditions for sustainability in the future. Application of efficient power generation cycles at low costs is essential for meeting this challenge. This applies also to municipal solid waste incineration with energy extraction, which should be preferred to its dumping in landfills. Hybrid dual-fuel combined cycle units are a simple and affordable way to increase the electric efficiency of biofuel energy utilization, without big investments, uncertainties or loss of reliability arising from complicated technologies. Configurations of such power cycles are very flexible and reliable. Their potential for high electric efficiency in condensing mode, high total efficiency in combined heat and power mode and unrivalled load flexibility is explored in this project. The present report is a literature study that concentrates on certain biomass utilization technologies, in particular the design and performance of hybrid combined cycle power units of various configurations, with gas turbines and internal combustion engines as topping cycles. An overview of published literature and general development trends on the relevant topic is presented. The study is extended to encompass a short overview of biomass utilization as an energy source (focusing on Sweden), history of combined cycles development with reference especially to combined cycles with supplementary firing and coal-fired hybrid combined cycles, repowering of old steam units into hybrid ones and combined cycles for internal combustion engines. The hybrid combined cycle concept for municipal solid waste

  13. Durability Indicators Comparison for SCC and CC in Tropical Coastal Environments.

    Science.gov (United States)

    Calado, Carlos; Camões, Aires; Monteiro, Eliana; Helene, Paulo; Barkokébas, Béda

    2015-03-27

    Self-compacting concrete (SCC) demands more studies of durability at higher temperatures when subjected to more aggressive environments in comparison to the conventional vibrated concrete (CC). This work aims at presenting results of durability indicators of SCC and CC, having the same water/binder relations and constituents. The applied methodologies were electrical resistivity, diffusion of chloride ions and accelerated carbonation experiments, among others, such as microstructure study, scanning electron microscope and microtomography experiments. The tests were performed in a research laboratory and at a construction site of the Pernambuco Arena. The obtained results shows that the SCC presents an average electrical resistivity 11.4% higher than CC; the average chloride ions diffusion was 63.3% of the CC; the average accelerated carbonation penetration was 45.8% of the CC; and the average open porosity was 55.6% of the CC. As the results demonstrated, the SCC can be more durable than CC, which contributes to elucidate the aspects related to its durability and consequent prolonged life cycle.

  14. The efficacy of metformin and clomiphene citrate combination compared with clomiphene citrate alone for ovulation induction in infertile patients with PCOS

    Directory of Open Access Journals (Sweden)

    Papa Dasari

    2009-01-01

    Full Text Available Context: Low ovulatory and pregnancy rates with clomiphene citrate (CC in anovulatory polycystic ovarian syndrome (PCOS. Aim: To find out the ovulatory and pregnancy rates in infertile PCOS subjects who receive CC alone and a combination of metformin and CC. Setting and Design: A prospective controlled clinical trial conducted in the outpatient department from August 2003 to August 2005. Materials and Methods: Twenty-four infertile PCOS women received CC alone at incremental doses of 50 mg up to 150 mg for three cycles and then at a dose of 150 mg for another three cycles (control group. The study group (16 PCOS received the same dose of CC along with 1500mg of metformin. Ovulation was monitored by transvaginal sonography up to six cycles or till pregnancy occurred. Statistical Analysis: This was carried out using software SSPS, version 10. Fisher′s exact test was used to calculate the ovulatory rates. Nine subjects of the control group who failed to conceive with CC had opted for CC and metformin and their ovulatory rate was calculated using statistical software, namely SPSS 15.0, Stata 8.0, MedCalc 9.0.1 and Systat 11.0 using Fischer′s exact test. Results: The metformin and clomiphene combination resulted in a significantly higher rate of ovulation ( P = 0.0016. The pregnancy rate was 8% with CC and 24% with metformin and CC. The CC failure group also ovulated at a similar rate as that of the study group. Conclusions: The ovulatory rate and the pregnancy rate with the metformin-CC combination was found to be higher when compared with CC alone. Metformin increased the ovulatory rate in CC failures, also implying increased sensitivity to CC.

  15. Analysis of a combined Rankine-vapour-compression refrigeration cycle

    International Nuclear Information System (INIS)

    Aphornratana, Satha; Sriveerakul, Thanarath

    2010-01-01

    This paper describes a theoretical analysis of a heat-powered refrigeration cycle, a combined Rankine-vapour-compression refrigeration cycle. This refrigeration cycle combines an Organic Rankine Cycle and a vapour-compression cycle. The cycle can be powered by low grade thermal energy as low as 60 deg. C and can produce cooling temperature as low as -10 deg. C. In the analysis, two combined Rankine-vapour-compression refrigeration cycles were investigated: the system with R22 and the system with R134a. Calculated COP values between 0.1 and 0.6 of both the systems were found.

  16. Archive of Geosample Data and Information from the Oregon State University (OSU) College of Earth, Ocean and Atmospheric Sciences (CEOAS) Marine Geology Repository (MGR)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Oregon State University Marine Geology Repository (OSU-MGR) is a partner in the Index to Marine and Lacustrine Geological Samples (IMLGS) database, contributing...

  17. Coordinated control of a combined cycle thermoelectric central; Control coordinado de una central termoelectrica de ciclo combinado

    Energy Technology Data Exchange (ETDEWEB)

    Sanchez Parra, Marino; Castelo Cuevas, Luis [Instituto de Investigaciones Electricas, Cuernavaca (Mexico)

    1998-03-01

    In this paper the coordinated control (CC) of the Distributed Control System (Sistema de Control Distribuido) (SICODI) of the Combined Cycle Central of Gomez Palacio, Durango, is presented. The description of the control scheme and its realization in software is made. From the scheme the operation strategies and automation, supervision and control are described in detail. The software components of the programming are described, the program structure and control data and its implementation in working stations VAX 3100 under the operating system VMS (Virtual Memory System), are described. [Espanol] En este articulo se presenta el control coordinado (CC) del Sistema de Control Distribuido (Sicodi) de la central de ciclo combinado Gomez Palacio, Durango. Se describe el esquema de control y su realizacion en software. Del esquema se detallan las estrategias de operacion y automatizacion, supervision y control. Del software se describen los componentes de la programacion, la estructura de programas y datos del control y su implementacion en estaciones de trabajo VAX 3100 bajo el sistema operativo VMS (Virtual Memory System).

  18. Durability Indicators Comparison for SCC and CC in Tropical Coastal Environments

    Directory of Open Access Journals (Sweden)

    Carlos Calado

    2015-03-01

    Full Text Available Self-compacting concrete (SCC demands more studies of durability at higher temperatures when subjected to more aggressive environments in comparison to the conventional vibrated concrete (CC. This work aims at presenting results of durability indicators of SCC and CC, having the same water/binder relations and constituents. The applied methodologies were electrical resistivity, diffusion of chloride ions and accelerated carbonation experiments, among others, such as microstructure study, scanning electron microscope and microtomography experiments. The tests were performed in a research laboratory and at a construction site of the Pernambuco Arena. The obtained results shows that the SCC presents an average electrical resistivity 11.4% higher than CC; the average chloride ions diffusion was 63.3% of the CC; the average accelerated carbonation penetration was 45.8% of the CC; and the average open porosity was 55.6% of the CC. As the results demonstrated, the SCC can be more durable than CC, which contributes to elucidate the aspects related to its durability and consequent prolonged life cycle.

  19. Sensitivity analysis of exergy destruction in a real combined cycle power plant based on advanced exergy method

    International Nuclear Information System (INIS)

    Boyaghchi, Fateme Ahmadi; Molaie, Hanieh

    2015-01-01

    Highlights: • The advanced exergy destruction components of a real CCPP are calculated. • The TIT and r c variation are investigated on exergy destruction parts of the cycle. • The TIT and r c growth increase the improvement potential in the most of components. • The TIT and r c growth decrease the unavoidable part in some components. - Abstract: The advanced exergy analysis extends engineering knowledge beyond the respective conventional methods by improving the design and operation of energy conversion systems. In advanced exergy analysis, the exergy destruction is splitting into endogenous/exogenous and avoidable/unavoidable parts. In this study, an advanced exergy analysis of a real combined cycle power plant (CCPP) with supplementary firing is done. The endogenous/exogenous irreversibilities of each component as well as their combination with avoidable/unavoidable irreversibilities are determined. A parametric study is presented discussing the sensitivity of various performance indicators to the turbine inlet temperature (TIT), and compressor pressure ratio (r c ). It is observed that the thermal and exergy efficiencies increase when TIT and r c rise. Results show that combustion chamber (CC) concentrates most of the exergy destruction (more than 62%), dominantly in unavoidable endogenous form which is decreased by 11.89% and 13.12% while the avoidable endogenous exergy destruction increase and is multiplied by the factors of 1.3 and 8.6 with increasing TIT and r c , respectively. In addition, TIT growth strongly increases the endogenous avoidable exergy destruction in high pressure superheater (HP.SUP), CC and low pressure evaporator (LP.EVAP). It, also, increases the exogenous avoidable exergy destruction of HP.SUP and low pressure steam turbine (LP.ST) and leads to the high decrement in the endogenous exergy destruction of the preheater (PRE) by about 98.8%. Furthermore, r c growth extremely rises the endogenous avoidable exergy destruction of gas

  20. Study of combined cycle engine for aerospace plane

    OpenAIRE

    苅田, 丈士; KANDA, Takeshi; 工藤, 賢司; KUDO, Kenji

    2002-01-01

    At the Ramjet Propulsion Research Center, the scramjet engine for an aerospace plane has been studied. Other engines are required for the plane to go into orbit. Recently, a combined cycle engine including scramjet mode has been also studied to complete the engine system for the plane. The scramjet and the combined cycle engine are most effective with application to the Single-Stage-to-Orbit (SSTO) aerospace plane, as shown in Figure 1. Recent activity on the combined cycle engine and the SST...

  1. Airbreathing combined cycle engine systems

    Science.gov (United States)

    Rohde, John

    1992-01-01

    The Air Force and NASA share a common interest in developing advanced propulsion systems for commercial and military aerospace vehicles which require efficient acceleration and cruise operation in the Mach 4 to 6 flight regime. The principle engine of interest is the turboramjet; however, other combined cycles such as the turboscramjet, air turborocket, supercharged ejector ramjet, ejector ramjet, and air liquefaction based propulsion are also of interest. Over the past months careful planning and program implementation have resulted in a number of development efforts that will lead to a broad technology base for those combined cycle propulsion systems. Individual development programs are underway in thermal management, controls materials, endothermic hydrocarbon fuels, air intake systems, nozzle exhaust systems, gas turbines and ramjet ramburners.

  2. Advanced modeling and simulation of integrated gasification combined cycle power plants with CO2-capture

    International Nuclear Information System (INIS)

    Rieger, Mathias

    2014-01-01

    The objective of this thesis is to provide an extensive description of the correlations in some of the most crucial sub-processes for hard coal fired IGCC with carbon capture (CC-IGCC). For this purpose, process simulation models are developed for four industrial gasification processes, the CO-shift cycle, the acid gas removal unit, the sulfur recovery process, the gas turbine, the water-/steam cycle and the air separation unit (ASU). Process simulations clarify the influence of certain boundary conditions on plant operation, performance and economics. Based on that, a comparative benchmark of CC-IGCC concepts is conducted. Furthermore, the influence of integration between the gas turbine and the ASU is analyzed in detail. The generated findings are used to develop an advanced plant configuration with improved economics. Nevertheless, IGCC power plants with carbon capture are not found to be an economically efficient power generation technology at present day boundary conditions.

  3. Gasification and combined cycles: Present situation and future prospects

    International Nuclear Information System (INIS)

    Brustia, G.F.; Bressan, L.; Domenichini, R.

    1992-01-01

    The gasification of coal and/or residual fuels from refineries together with the use of combined cycle power generation systems represents a technically and economically feasible method for the conversion of poor quality fossil fuels into electric power. The conversion is accomplished with maximum respect for the severest environmental normatives. In addition, foreseen technical improvements for components and plant systems are expected to heighten the marketing potential of gasification/combined cycle power plants. After Italy's moratorium on nuclear energy, the passing eras of conventional fossil fuel and then combined cycle power plants, the need for highly competitive industrial production technologies and the urgency of nation-wide energy conservation appear to be ushering in the new era of gasification with combined cycles

  4. Parametric Investigation and Thermoeconomic Optimization of a Combined Cycle for Recovering the Waste Heat from Nuclear Closed Brayton Cycle

    Directory of Open Access Journals (Sweden)

    Lihuang Luo

    2016-01-01

    Full Text Available A combined cycle that combines AWM cycle with a nuclear closed Brayton cycle is proposed to recover the waste heat rejected from the precooler of a nuclear closed Brayton cycle in this paper. The detailed thermodynamic and economic analyses are carried out for the combined cycle. The effects of several important parameters, such as the absorber pressure, the turbine inlet pressure, the turbine inlet temperature, the ammonia mass fraction, and the ambient temperature, are investigated. The combined cycle performance is also optimized based on a multiobjective function. Compared with the closed Brayton cycle, the optimized power output and overall efficiency of the combined cycle are higher by 2.41% and 2.43%, respectively. The optimized LEC of the combined cycle is 0.73% lower than that of the closed Brayton cycle.

  5. Combined rankine and vapor compression cycles

    Science.gov (United States)

    Radcliff, Thomas D.; Biederman, Bruce P.; Brasz, Joost J.

    2005-04-19

    An organic rankine cycle system is combined with a vapor compression cycle system with the turbine generator of the organic rankine cycle generating the power necessary to operate the motor of the refrigerant compressor. The vapor compression cycle is applied with its evaporator cooling the inlet air into a gas turbine, and the organic rankine cycle is applied to receive heat from a gas turbine exhaust to heat its boiler within one embodiment, a common condenser is used for the organic rankine cycle and the vapor compression cycle, with a common refrigerant, R-245a being circulated within both systems. In another embodiment, the turbine driven generator has a common shaft connected to the compressor to thereby eliminate the need for a separate motor to drive the compressor. In another embodiment, an organic rankine cycle system is applied to an internal combustion engine to cool the fluids thereof, and the turbo charged air is cooled first by the organic rankine cycle system and then by an air conditioner prior to passing into the intake of the engine.

  6. Advanced modeling and simulation of integrated gasification combined cycle power plants with CO{sub 2}-capture

    Energy Technology Data Exchange (ETDEWEB)

    Rieger, Mathias

    2014-04-17

    The objective of this thesis is to provide an extensive description of the correlations in some of the most crucial sub-processes for hard coal fired IGCC with carbon capture (CC-IGCC). For this purpose, process simulation models are developed for four industrial gasification processes, the CO-shift cycle, the acid gas removal unit, the sulfur recovery process, the gas turbine, the water-/steam cycle and the air separation unit (ASU). Process simulations clarify the influence of certain boundary conditions on plant operation, performance and economics. Based on that, a comparative benchmark of CC-IGCC concepts is conducted. Furthermore, the influence of integration between the gas turbine and the ASU is analyzed in detail. The generated findings are used to develop an advanced plant configuration with improved economics. Nevertheless, IGCC power plants with carbon capture are not found to be an economically efficient power generation technology at present day boundary conditions.

  7. CANDU combined cycles featuring gas-turbine engines

    International Nuclear Information System (INIS)

    Vecchiarelli, J.; Choy, E.; Peryoga, Y.; Aryono, N.A.

    1998-01-01

    In the present study, a power-plant analysis is conducted to evaluate the thermodynamic merit of various CANDU combined cycles in which continuously operating gas-turbine engines are employed as a source of class IV power restoration. It is proposed to utilize gas turbines in future CANDU power plants, for sites (such as Indonesia) where natural gas or other combustible fuels are abundant. The primary objective is to eliminate the standby diesel-generators (which serve as a backup supply of class III power) since they are nonproductive and expensive. In the proposed concept, the gas turbines would: (1) normally operate on a continuous basis and (2) serve as a reliable backup supply of class IV power (the Gentilly-2 nuclear power plant uses standby gas turbines for this purpose). The backup class IV power enables the plant to operate in poison-prevent mode until normal class IV power is restored. This feature is particularly beneficial to countries with relatively small and less stable grids. Thermodynamically, the advantage of the proposed concept is twofold. Firstly, the operation of the gas-turbine engines would directly increase the net (electrical) power output and the overall thermal efficiency of a CANDU power plant. Secondly, the hot exhaust gases from the gas turbines could be employed to heat water in the CANDU Balance Of Plant (BOP) and therefore improve the thermodynamic performance of the BOP. This may be accomplished via several different combined-cycle configurations, with no impact on the current CANDU Nuclear Steam Supply System (NSSS) full-power operating conditions when each gas turbine is at maximum power. For instance, the hot exhaust gases may be employed for feedwater preheating and steam reheating and/or superheating; heat exchange could be accomplished in a heat recovery steam generator, as in conventional gas-turbine combined-cycle plants. The commercially available GateCycle power plant analysis program was applied to conduct a

  8. Maximisation of Combined Cycle Power Plant Efficiency

    Directory of Open Access Journals (Sweden)

    Janusz Kotowicz

    2015-12-01

    Full Text Available The paper presents concepts for increasing the efficiency of a modern combined cycle power plant. Improvement of gas turbine performance indicators as well as recovering heat from the air cooling the gas turbine’s flow system enable reaching gross electrical efficiencies of around 65%. Analyses for a wide range of compressor pressure ratios were performed. Operating characteristics were developed for the analysed combined cycle plant, for different types of open air cooling arrangements of the gas turbine’s expander: convective, transpiration and film.

  9. Diagnostic system for combine cycle power plant

    International Nuclear Information System (INIS)

    Shimizu, Yujiro; Nomura, Masumi; Tanaka, Satoshi; Ito, Ryoji; Kita, Yoshiyuki

    2000-01-01

    We developed the Diagnostic System for Combined Cycle Power Plant which enables inexperienced operators as well as experienced operators to cope with abnormal conditions of Combined Cycle Power Plant. The features of this system are the Estimate of Emergency Level for Operation and the Prediction of Subsequent Abnormality, adding to the Diagnosis of Cause and the Operation Guidance. Moreover in this system, Diagnosis of Cause was improved by using our original method and support screens can be displayed for educational means in normal condition as well. (Authors)

  10. A comparison of advanced heat recovery power cycles in a combined cycle for large ships

    International Nuclear Information System (INIS)

    Larsen, Ulrik; Sigthorsson, Oskar; Haglind, Fredrik

    2014-01-01

    Strong motivation exists within the marine sector to reduce fuel expenses and to comply with ever stricter emission regulations. Heat recovery can address both of these issues. The ORC (organic Rankine cycle), the Kalina cycle and the steam Rankine cycle have received the majority of the focus in the literature. In the present work we compare these cycles in a combined cycle application with a large marine two-stroke diesel engine. We present an evaluation of the efficiency and the environmental impact, safety concerns and practical aspects of each of the cycles. A previously validated numerical engine model is combined with a turbocharger model and bottoming cycle models written in Matlab. Genetic algorithm optimisation results suggest that the Kalina cycle possess no significant advantages compared to the ORC or the steam cycle. While contributing to very high efficiencies, the organic working fluids possess high global warming potentials and hazard levels. It is concluded that the ORC has the greatest potential for increasing the fuel efficiency, and the combined cycle offers very high thermal efficiency. While being less efficient, the steam cycle has the advantages of being well proven, harmless to the environment as well as being less hazardous in comparison. - Highlights: • We compare steam, ORC (organic Rankine cycle) and Kalina cycles for waste heat recovery in marine engines. • We evaluate the efficiency and important qualitative differences. • The Kalina cycle presents no apparent advantages. • The steam cycle is well known, harmless and has a high efficiency. • The ORC has the highest efficiency but also important drawbacks

  11. Parametric analysis and optimization for a combined power and refrigeration cycle

    International Nuclear Information System (INIS)

    Wang Jiangfeng; Dai Yiping; Gao Lin

    2008-01-01

    A combined power and refrigeration cycle is proposed, which combines the Rankine cycle and the absorption refrigeration cycle. This combined cycle uses a binary ammonia-water mixture as the working fluid and produces both power output and refrigeration output simultaneously with only one heat source. A parametric analysis is conducted to evaluate the effects of thermodynamic parameters on the performance of the combined cycle. It is shown that heat source temperature, environment temperature, refrigeration temperature, turbine inlet pressure, turbine inlet temperature, and basic solution ammonia concentration have significant effects on the net power output, refrigeration output and exergy efficiency of the combined cycle. A parameter optimization is achieved by means of genetic algorithm to reach the maximum exergy efficiency. The optimized exergy efficiency is 43.06% under the given condition

  12. Cohort Profile: Antiretroviral Therapy Cohort Collaboration (ART-CC)

    Science.gov (United States)

    May, Margaret T; Ingle, Suzanne M; Costagliola, Dominique; Justice, Amy C; de Wolf, Frank; Cavassini, Matthias; D’Arminio Monforte, Antonella; Casabona, Jordi; Hogg, Robert S; Mocroft, Amanda; Lampe, Fiona C; Dabis, François; Fätkenheuer, Gerd; Sterling, Timothy R; del Amo, Julia; Gill, M John; Crane, Heidi M; Saag, Michael S; Guest, Jodie; Brodt, Hans-Reinhard; Sterne, Jonathan AC

    2014-01-01

    The advent of effective combination antiretroviral therapy (ART) in 1996 resulted in fewer patients experiencing clinical events, so that some prognostic analyses of individual cohort studies of human immunodeficiency virus-infected individuals had low statistical power. Because of this, the Antiretroviral Therapy Cohort Collaboration (ART-CC) of HIV cohort studies in Europe and North America was established in 2000, with the aim of studying the prognosis for clinical events in acquired immune deficiency syndrome (AIDS) and the mortality of adult patients treated for HIV-1 infection. In 2002, the ART-CC collected data on more than 12,000 patients in 13 cohorts who had begun combination ART between 1995 and 2001. Subsequent updates took place in 2004, 2006, 2008, and 2010. The ART-CC data base now includes data on more than 70 000 patients participating in 19 cohorts who began treatment before the end of 2009. Data are collected on patient demographics (e.g. sex, age, assumed transmission group, race/ethnicity, geographical origin), HIV biomarkers (e.g. CD4 cell count, plasma viral load of HIV-1), ART regimen, dates and types of AIDS events, and dates and causes of death. In recent years, additional data on co-infections such as hepatitis C; risk factors such as smoking, alcohol and drug use; non-HIV biomarkers such as haemoglobin and liver enzymes; and adherence to ART have been collected whenever available. The data remain the property of the contributing cohorts, whose representatives manage the ART-CC via the steering committee of the Collaboration. External collaboration is welcomed. Details of contacts are given on the ART-CC website (www.art-cohort-collaboration.org). PMID:23599235

  13. Seasonal cycle of the Canary Current.

    Science.gov (United States)

    Vélez-Belchí, P.; Hernandez-Guerra, A.; Pérez-Hernández, M. D.

    2015-12-01

    The Atlantic meridional overturning circulation (AMOC) is recognized as an important component of the climate system, contributing to the relatively mild climate of northwest Europe. Due to its importance, the strength of the AMOC is continually monitored along 26ºN with several moorings east of the Bahamas, in the Middle Atlantic Ridge and south of the Canary islands, known as the RAPID array. The measurements of the RAPID array show a 6 Sv seasonal cycle for the AMOC, and recent studies have pointed out the dynamics of the eastern Atlantic as the main driver for this seasonal cycle, specifically, rossby waves excited south of the Canary Islands. Due to the important role of the eastern Atlantic, in this study we describe the seasonal cycle of the Canary Current (CC) and the Canary Upwelling Current (CUC) using hydrographic data from two cruises carried out in a box around the Canary Islands, the region where the eastern component of the RAPID array is placed. CTD, VMADCP and LADCP data were combined with inverse modeling in order to determine absolute geostrophic transports in the Canary Islands region in fall and spring. During spring, the overall transport of Canary Current and the CUC was southward. In the Lanzarote Passage (LP), between the Canary Islands and Africa, the CUC transported 0.6±0.20 Sv southward, while the Canary Current transported 1.0±0.40 Sv in the oceanic waters of the Canary Islands Archipelago. During fall, the CUC transported 2.8±0.4Sv northward, while the CC transported 2.9±0.60 Sv southward in the oceanic waters of the Canary Islands Archipelago. The seasonal cycle observed has an amplitude of 3.4Sv for the CUC and 1.9Sv for the CC. Data from a mooring in the LP and the hydrographic data was used to calibrate geostrophic transport estimated using altimetry data. The amplitude of the seasonal cycle of the geostrophic transport obtained using the calibrated altimetry data (Figure 1) was quite similar to the seasonal cycle of the

  14. Thermodynamic performance optimization of a combined power/cooling cycle

    International Nuclear Information System (INIS)

    Pouraghaie, M.; Atashkari, K.; Besarati, S.M.; Nariman-zadeh, N.

    2010-01-01

    A combined thermal power and cooling cycle has already been proposed in which thermal energy is used to produce work and to generate a sub-ambient temperature stream that is suitable for cooling applications. The cycle uses ammonia-water mixture as working fluid and is a combination of a Rankine cycle and absorption cycle. The very high ammonia vapor concentration, exiting turbine under certain operating conditions, can provide power output as well as refrigeration. In this paper, the goal is to employ multi-objective algorithms for Pareto approach optimization of thermodynamic performance of the cycle. It has been carried out by varying the selected design variables, namely, turbine inlet pressure (P h ), superheater temperature (T superheat ) and condenser temperature (T condensor ). The important conflicting thermodynamic objective functions that have been considered in this study are turbine work (w T ), cooling capacity (q cool ) and thermal efficiency (η th ) of the cycle. It is shown that some interesting and important relationships among optimal objective functions and decision variables involved in the combined cycle can be discovered consequently. Such important relationships as useful optimal design principles would have not been obtained without the use of a multi-objective optimization approach.

  15. The future of integrated coal gasification combined cycle power plants

    International Nuclear Information System (INIS)

    Mueller, R.; Termuehlen, H.

    1991-01-01

    This paper examines the future of integrated coal gasification combined cycle (IGCC) power plants as affected by various technical, economical and environmental trends in power generation. The topics of the paper include a description of natural gas-fired combined cycle power plants, IGCC plants, coal gasifier concepts, integration of gasifiers into combined cycle power plants, efficiency, environmental impacts, co-products of IGCC power plants, economics of IGCC power plants, and a review of IGCC power plant projects

  16. A combined cycle utilizing LNG and low-temperature solar energy

    International Nuclear Information System (INIS)

    Rao, Wen-Ji; Zhao, Liang-Ju; Liu, Chao; Zhang, Mo-Geng

    2013-01-01

    This paper has proposed a combined cycle, in which low-temperature solar energy and cold energy of liquefied natural gas (LNG) can be effectively utilized together. Comparative analysis based on a same net work output between the proposed combined cycle and separated solar ORC and LNG vapor system has been done. The results show that, for the combined cycle, a decrease of nearly 82.2% on the area of solar collector is obtained and the area of heat exchanger decreases by 31.7%. Moreover, exergy efficiency is higher than both two separated systems. This work has also dealt with the thermodynamic analyses for the proposed cycle. The results show that R143a followed by propane and propene emerges as most suitable fluid. Moreover, with a regenerator added in the cycle, performance improvement is obtained for the reduction on area of solar collector and increase on system efficiency and exergy efficiency. -- Highlights: • A combined cycle utilizing low-temperature solar energy and LNG together is proposed. • Five objection functions are used to decide the best working fluids. • Cycle with a regenerator has good performance

  17. Parametric analysis for a new combined power and ejector-absorption refrigeration cycle

    International Nuclear Information System (INIS)

    Wang Jiangfeng; Dai Yiping; Zhang Taiyong; Ma Shaolin

    2009-01-01

    A new combined power and ejector-absorption refrigeration cycle is proposed, which combines the Rankine cycle and the ejector-absorption refrigeration cycle, and could produce both power output and refrigeration output simultaneously. This combined cycle, which originates from the cycle proposed by authors previously, introduces an ejector between the rectifier and the condenser, and provides a performance improvement without greatly increasing the complexity of the system. A parametric analysis is conducted to evaluate the effects of the key thermodynamic parameters on the cycle performance. It is shown that heat source temperature, condenser temperature, evaporator temperature, turbine inlet pressure, turbine inlet temperature, and basic solution ammonia concentration have significant effects on the net power output, refrigeration output and exergy efficiency of the combined cycle. It is evident that the ejector can improve the performance of the combined cycle proposed by authors previously.

  18. Temporal fluxomics reveals oscillations in TCA cycle flux throughout the mammalian cell cycle.

    Science.gov (United States)

    Ahn, Eunyong; Kumar, Praveen; Mukha, Dzmitry; Tzur, Amit; Shlomi, Tomer

    2017-11-06

    Cellular metabolic demands change throughout the cell cycle. Nevertheless, a characterization of how metabolic fluxes adapt to the changing demands throughout the cell cycle is lacking. Here, we developed a temporal-fluxomics approach to derive a comprehensive and quantitative view of alterations in metabolic fluxes throughout the mammalian cell cycle. This is achieved by combining pulse-chase LC-MS-based isotope tracing in synchronized cell populations with computational deconvolution and metabolic flux modeling. We find that TCA cycle fluxes are rewired as cells progress through the cell cycle with complementary oscillations of glucose versus glutamine-derived fluxes: Oxidation of glucose-derived flux peaks in late G1 phase, while oxidative and reductive glutamine metabolism dominates S phase. These complementary flux oscillations maintain a constant production rate of reducing equivalents and oxidative phosphorylation flux throughout the cell cycle. The shift from glucose to glutamine oxidation in S phase plays an important role in cell cycle progression and cell proliferation. © 2017 The Authors. Published under the terms of the CC BY 4.0 license.

  19. Fluorouracil and high-dose leucovorin with radiotherapy as adjuvant therapy for rectal cancer. Results of a phase II study

    Energy Technology Data Exchange (ETDEWEB)

    Giralt, J. [Radiation Oncology Service, Hospital General Universitari Vall d`Hebron, Barcelona (Spain); Rubio, D. [Medical Oncology Service, Hospital General Universitari Vall d`Hebron, Barcelona (Spain); Maldonado, X. [Radiation Oncology Service, Hospital General Universitari Vall d`Hebron, Barcelona (Spain); Naval, J. [Dept. of Surgery, Hospital General Universitari Vall d`Hebron, Barcelona (Spain); Casado, S. [Medical Oncology Service, Hospital General Universitari Vall d`Hebron, Barcelona (Spain); Lara, F. [Dept. of Surgery, Hospital General Universitari Vall d`Hebron, Barcelona (Spain); Rosello, J.M. [Dept. of Preventive Medicine, Hospital General Universitari Vall d`Hebron, Barcelona (Spain); Armengol, M. [Dept. of Surgery, Hospital General Universitari Vall d`Hebron, Barcelona (Spain)

    1997-07-01

    The purpose of this phase II study was to evaluate the efficacy and toxicity of fluorouracil and high-dose leucovorin (5-FU/LV) with pelvic irradiation as adjuvant therapy for patients with macroscopical resected rectal or recto-sigmoid cancer. Following surgery for stages II-III primary (52) or recurrent rectal cancer (4), 56 patients received 8 cycles of 5-FU/LV and pelvic irradiation. 5-FU doses were 200 mgr/m{sup 2} for cycles 2-3 and 300 mgr/m{sup 2} for cycles 1 and 4-8. LV doses remained fixed at 200 mgr/m{sup 2}. Pelvic radiation was started in the third week, between the first and second cycle. The total dose was 50.4 Gy. No serve complications had been recorded. The incidence of grade 3 diarrhea was 19%. Three patients presented leukopenia grade 3 (5%). In 44 patients (78%) the planned treatment could be administered. The median follow-up was 40 months (range 22-66). Seven patients had a local relapse (13%) and 6 developed distant metastasis (10%). The 3-year disease-free survival was 72% and the overall survival was 76%. These preliminary results show that combined post-operative 5-FU/LV and pelvic radiotherapy are well tolerated and present a reasonable local control and survival rates. This adjuvant treatment should be evaluated in randomized trials. (orig.).

  20. Comparative performance analysis of combined-cycle pulse detonation turbofan engines (PDTEs

    Directory of Open Access Journals (Sweden)

    Sudip Bhattrai

    2013-09-01

    Full Text Available Combined-cycle pulse detonation engines are promising contenders for hypersonic propulsion systems. In the present study, design and propulsive performance analysis of combined-cycle pulse detonation turbofan engines (PDTEs is presented. Analysis is done with respect to Mach number at two consecutive modes of operation: (1 Combined-cycle PDTE using a pulse detonation afterburner mode (PDA-mode and (2 combined-cycle PDTE in pulse detonation ramjet engine mode (PDRE-mode. The performance of combined-cycle PDTEs is compared with baseline afterburning turbofan and ramjet engines. The comparison of afterburning modes is done for Mach numbers from 0 to 3 at 15.24 km altitude conditions, while that of pulse detonation ramjet engine (PDRE is done for Mach 1.5 to Mach 6 at 18.3 km altitude conditions. The analysis shows that the propulsive performance of a turbine engine can be greatly improved by replacing the conventional afterburner with a pulse detonation afterburner (PDA. The PDRE also outperforms its ramjet counterpart at all flight conditions considered herein. The gains obtained are outstanding for both the combined-cycle PDTE modes compared to baseline turbofan and ramjet engines.

  1. Thermodynamic Analysis of an Integrated Solid Oxide Fuel Cell Cycle with a Rankine Cycle

    DEFF Research Database (Denmark)

    Rokni, Masoud

    2010-01-01

    Hybrid systems consisting of Solid Oxide Fuel Cells (SOFC) on the top of a Steam Turbine (ST) are investigated. The plants are fired by natural gas (NG). A desulfurization reactor removes the sulfur content in the fuel while a pre-reformer breaks down the heavier hydrocarbons. The pre-treated fuel......% are achieved which is considerably higher than the conventional Combined Cycles (CC). Both ASR (Adiabatic Steam Reformer) and CPO (Catalytic Partial Oxidation) fuel pre-reformer reactors are considered in this investigation....

  2. Exergy analysis of a combined power and cooling cycle

    International Nuclear Information System (INIS)

    Fontalvo, Armando; Pinzon, Horacio; Duarte, Jorge; Bula, Antonio; Quiroga, Arturo Gonzalez; Padilla, Ricardo Vasquez

    2013-01-01

    This paper presents a comprehensive exergy analysis of a combined power and cooling cycle which combines a Rankine and absorption refrigeration cycle by using ammonia–water mixture as working fluid. A thermodynamic model was developed in Matlab ® to find out the effect of pressure ratio, ammonia mass fraction at the absorber and turbine efficiency on the total exergy destruction of the cycle. The contribution of each cycle component on the total exergy destruction was also determined. The results showed that total exergy destruction decreases when pressure ratio increases, and reaches a maximum at x ≈ 0.5, when ammonia mass fraction is varied at absorber. Also, it was found that the absorber, the boiler and the turbine had the major contribution to the total exergy destruction of the cycle, and the increase of the turbine efficiency reduces the total exergy destruction. The effect of rectification cooling source (external and internal) on the cycle output was investigated, and the results showed that internal rectification cooling reduces the total exergy destruction of the cycle. Finally, the effect of the presence or absence of the superheater after the rectification process was determined and it was obtained that the superheated condition reduces the exergy destruction of the cycle at high turbine efficiency values. Highlights: • A parametric exergy analysis of a combined power and cooling cycle is performed. • Two scenarios for rectifier cooling (internal and external) were studied. • Internal cooling source is more exergetic efficient than external cooling source. • The absorber and boiler have the largest total exergy destruction. • Our results show that the superheater reduces the exergy destruction of the cycle

  3. Combined Turbine and Cycle Optimization for Organic Rankine Cycle Power Systems—Part A

    DEFF Research Database (Denmark)

    Meroni, Andrea; La Seta, Angelo; Andreasen, Jesper Graa

    2016-01-01

    Axial-flow turbines represent a well-established technology for a wide variety of power generation systems. Compactness, flexibility, reliability and high efficiency have been key factors for the extensive use of axial turbines in conventional power plants and, in the last decades, in organic...... Rankine cycle power systems. In this two-part paper, an overall cycle model and a model of an axial turbine were combined in order to provide a comprehensive preliminary design of the organic Rankine cycle unit, taking into account both cycle and turbine optimal designs. Part A presents the preliminary...

  4. Air bottoming cycle, an alternative to combined cycles. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Kaikko, J. [Royal Inst. of Techn., Stockholm (Sweden). Dept. of Energy Technology

    2001-10-01

    In this work, the idea of Air Bottoming Cycle (ABC) has been studied. The objectives for the work have been to establish an understanding of the concept for power and heat generation as well as to find - if possible - feasible concepts for future use in the Swedish energy system. Combined cycle in power generation is an established technology. In the conventional combined cycle, a gas turbine works as a topping cycle together with the steam (Rankine) bottoming cycle. In the ABC the steam bottoming cycle is replaced with a gas turbine (Brayton) bottoming cycle having air as a working fluid. The two gas turbines are thermally connected over a gas-to-gas heat exchanger. This concept promises savings in weight and cost, as well as operating benefits, compared to the Rankine bottoming technology. The ABC has been modelled using a heat balance program, and a parametric study for the concept optimisation as well as for off-design analysis has been performed. Performance of the ABC has been compared to other, established technologies. A preliminary economic evaluation has been made. As a result of the study, it is clarified that the Rankine bottoming cycle with steam remains superior to the ABC as regards electrical efficiency in the medium and large power scale. For small-scale applications (<10 MW{sub e}) where the thermodynamic advantage of the Rankine cycle is not dominating any longer and its economy is burdened by the heavy investment structure, the ABC becomes the better alternative for energy utilisation. A preliminary economic evaluation shows that (at energy prices autumn 2000) the ABC is at the same level as the comparable small-scale cogeneration installations. Due to high power-to-heat ratio however, higher electricity prices will favour the ABC. One interesting feature of the ABC is that about 50% of the dissipated low-value heat from the cycle is carried by clean (sterile) air at the temperature around 200 deg C. This air can be utilised for space heating or

  5. Thermodynamic analysis of heat recovery steam generator in combined cycle power plant

    Directory of Open Access Journals (Sweden)

    Ravi Kumar Naradasu

    2007-01-01

    Full Text Available Combined cycle power plants play an important role in the present energy sector. The main challenge in designing a combined cycle power plant is proper utilization of gas turbine exhaust heat in the steam cycle in order to achieve optimum steam turbine output. Most of the combined cycle developers focused on the gas turbine output and neglected the role of the heat recovery steam generator which strongly affects the overall performance of the combined cycle power plant. The present paper is aimed at optimal utilization of the flue gas recovery heat with different heat recovery steam generator configurations of single pressure and dual pressure. The combined cycle efficiency with different heat recovery steam generator configurations have been analyzed parametrically by using first law and second law of thermodynamics. It is observed that in the dual cycle high pressure steam turbine pressure must be high and low pressure steam turbine pressure must be low for better heat recovery from heat recovery steam generator.

  6. Gas fired combined cycle plant in Singapore: energy use, GWP and cost-a life cycle approach

    International Nuclear Information System (INIS)

    Kannan, R.; Leong, K.C.; Osman, Ramli; Ho, H.K.; Tso, C.P.

    2005-01-01

    A life cycle assessment was performed to quantify the non-renewable (fossil) energy use and global warming potential (GWP) in electricity generation from a typical gas fired combined cycle power plant in Singapore. The cost of electricity generation was estimated using a life cycle cost analysis (LCCA) tool. The life cycle assessment (LCA) of a 367.5 MW gas fired combined cycle power plant operating in Singapore revealed that hidden processes consume about 8% additional energy in addition to the fuel embedded energy, and the hidden GWP is about 18%. The natural gas consumed during the operational phase accounted for 82% of the life cycle cost of electricity generation. An empirical relation between plant efficiency and life cycle energy use and GWP in addition to a scenario for electricity cost with varying gas prices and plant efficiency have been established

  7. Optimised heat recovery steam generators for integrated solar combined cycle plants

    Science.gov (United States)

    Peterseim, Jürgen H.; Huschka, Karsten

    2017-06-01

    The cost of concentrating solar power (CSP) plants is decreasing but, due to the cost differences and the currently limited value of energy storage, implementation of new facilities is still slow compared to photovoltaic systems. One recognized option to lower cost instantly is the hybridization of CSP with other energy sources, such as natural gas or biomass. Various references exist for the combination of CSP with natural gas in combined cycle plants, also known as Integrated Solar Combined Cycle (ISCC) plants. One problem with current ISCC concepts is the so called ISCC crisis, which occurs when CSP is not contributing and cycle efficiency falls below efficiency levels of solely natural gas only fired combined cycle plants. This paper analyses current ISCC concepts and compares them with two optimised designs. The comparison is based on a Kuraymat type ISCC plant and shows that cycle optimization enables a net capacity increase of 1.4% and additional daily generation of up to 7.9%. The specific investment of the optimised Integrated Solar Combined Cycle plant results in a 0.4% cost increase, which is below the additional net capacity and daily generation increase.

  8. Air bottoming cycle, an alternative to combined cycles. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Kaikko, J. [Royal Inst. of Tech., Stockholm (Sweden). Dept. of Energy Technology

    2002-02-01

    In this work, the idea of Air Bottoming Cycle (ABC) has been studied. The objectives for the work have been to establish an understanding of the concept for power and heat generation as well as to find - if possible - feasible concepts for future use in the Swedish energy system. Combined cycle in power generation is an established technology. In the conventional combined cycle, a gas turbine works as a topping cycle together with the steam (Rankine) bottoming cycle. In the ABC the steam bottoming cycle is replaced with a gas turbine (Brayton) bottoming cycle having air as a working fluid. The two gas turbines are thermally connected over a gas-to-gas heat exchanger. This concept promises savings in weight and cost, as well as operating benefits, compared to the Rankine bottoming technology. The ABC has been modelled using a heat balance program, and a parametric study for the concept optimisation as well as for off-design analysis has been performed. Performance of the ABC has been compared to other, established technologies. A preliminary economic evaluation has been made. As a result of the study, it is clarified that the Rankine bottoming cycle with steam remains superior to the ABC as regards electrical efficiency in the medium and large power scale. For small-scale applications (<10 MW{sub e}) where the thermodynamic advantage of the Rankine cycle is not dominating any longer and its economy is burdened by the heavy investment structure, the ABC becomes the better alternative for energy utilisation. A preliminary economic evaluation shows that (at energy prices autumn 2000) the ABC is at the same level as the comparable small-scale cogeneration installations. Due to high power-to-heat ratio however, higher electricity prices will favour the ABC. One interesting feature of the ABC is that about 50% of the dissipated low-value heat from the cycle is carried by clean (sterile) air at the temperature around 200 deg C. This air can be utilised for space heating or

  9. Simulation of a combined-cycle engine

    Science.gov (United States)

    Vangerpen, Jon

    1991-01-01

    A FORTRAN computer program was developed to simulate the performance of combined-cycle engines. These engines combine features of both gas turbines and reciprocating engines. The computer program can simulate both design point and off-design operation. Widely varying engine configurations can be evaluated for their power, performance, and efficiency as well as the influence of altitude and air speed. Although the program was developed to simulate aircraft engines, it can be used with equal success for stationary and automative applications.

  10. A Novel Pentadentate Coordination Mode for the Carbonato Bridge: Synthesis, Crystal Structure, and Magnetic Behavior of (&mgr;(3)-CO(3))[Ni(3)(Medpt)(3)(NCS)(4)], a New Trinuclear Nickel(II) Carbonato-Bridged Complex with Strong Antiferromagnetic Coupling.

    Science.gov (United States)

    Escuer, Albert; Vicente, Ramon; Kumar, Sujit B.; Solans, Xavier; Font-Bardía, Mercé; Caneschi, Andrea

    1996-05-22

    The trinuclear complex (&mgr;(3)-CO(3))[Ni(3)(Medpt)(3)(NCS)(4)] was obtained by reaction of basic solutions of nickel(II), Medpt (bis(3aminopropyl)methylamine) and thiocyanate ligand with atmospheric CO(2) or by simple reaction with carbonate anion. (&mgr;(3)-CO(3))[Ni(3)(Medpt)(3)(NCS)(4)] crystallizes in the triclinic system, space group P&onemacr;, with a = 12.107(5) Å, b = 12.535(7) Å, c = 16.169(9) Å, alpha = 102.69(5) degrees, beta = 92.91(5) degrees, gamma = 118.01(4) degrees, Z = 2, and R = 0.043. The three nickel atoms are asymmetrically bridged by one pentadentate carbonato ligand, which shows a novel coordination mode. The (&mgr;(3)-CO(3))[Ni(3)(Medpt)(3)(NCS)(4)] compound shows a very strong antiferromagnetic coupling. Fit as irregular triangular arrangement gave J(1) = -88.4, J(2) = -57.7, and J(3) = -9.6 cm(-)(1), which is the strongest AF coupling observed to date for Ni(3) compounds. The magnetic behavior of the carbonato bridge is discussed.

  11. INTEGRATED PYROLYSIS COMBINED CYCLE BIOMASS POWER SYSTEM CONCEPT DEFINITION

    International Nuclear Information System (INIS)

    Sandvig, Eric; Walling, Gary; Brown, Robert C.; Pletka, Ryan; Radlein, Desmond; Johnson, Warren

    2003-01-01

    Advanced power systems based on integrated gasification/combined cycles (IGCC) are often presented as a solution to the present shortcomings of biomass as fuel. Although IGCC has been technically demonstrated at full scale, it has not been adopted for commercial power generation. Part of the reason for this situation is the continuing low price for coal. However, another significant barrier to IGCC is the high level of integration of this technology: the gas output from the gasifier must be perfectly matched to the energy demand of the gas turbine cycle. We are developing an alternative to IGCC for biomass power: the integrated (fast) pyrolysis/ combined cycle (IPCC). In this system solid biomass is converted into liquid rather than gaseous fuel. This liquid fuel, called bio-oil, is a mixture of oxygenated organic compounds and water that serves as fuel for a gas turbine topping cycle. Waste heat from the gas turbine provides thermal energy to the steam turbine bottoming cycle. Advantages of the biomass-fueled IPCC system include: combined cycle efficiency exceeding 37 percent efficiency for a system as small as 7.6 MW e ; absence of high pressure thermal reactors; decoupling of fuel processing and power generation; and opportunities for recovering value-added products from the bio-oil. This report provides a technical overview of the system including pyrolyzer design, fuel clean-up strategies, pyrolysate condenser design, opportunities for recovering pyrolysis byproducts, gas turbine cycle design, and Rankine steam cycle. The report also reviews the potential biomass fuel supply in Iowa, provide and economic analysis, and present a summery of benefits from the proposed system

  12. INTEGRATED PYROLYSIS COMBINED CYCLE BIOMASS POWER SYSTEM CONCEPT DEFINITION

    Energy Technology Data Exchange (ETDEWEB)

    Eric Sandvig; Gary Walling; Robert C. Brown; Ryan Pletka; Desmond Radlein; Warren Johnson

    2003-03-01

    Advanced power systems based on integrated gasification/combined cycles (IGCC) are often presented as a solution to the present shortcomings of biomass as fuel. Although IGCC has been technically demonstrated at full scale, it has not been adopted for commercial power generation. Part of the reason for this situation is the continuing low price for coal. However, another significant barrier to IGCC is the high level of integration of this technology: the gas output from the gasifier must be perfectly matched to the energy demand of the gas turbine cycle. We are developing an alternative to IGCC for biomass power: the integrated (fast) pyrolysis/ combined cycle (IPCC). In this system solid biomass is converted into liquid rather than gaseous fuel. This liquid fuel, called bio-oil, is a mixture of oxygenated organic compounds and water that serves as fuel for a gas turbine topping cycle. Waste heat from the gas turbine provides thermal energy to the steam turbine bottoming cycle. Advantages of the biomass-fueled IPCC system include: combined cycle efficiency exceeding 37 percent efficiency for a system as small as 7.6 MW{sub e}; absence of high pressure thermal reactors; decoupling of fuel processing and power generation; and opportunities for recovering value-added products from the bio-oil. This report provides a technical overview of the system including pyrolyzer design, fuel clean-up strategies, pyrolysate condenser design, opportunities for recovering pyrolysis byproducts, gas turbine cycle design, and Rankine steam cycle. The report also reviews the potential biomass fuel supply in Iowa, provide and economic analysis, and present a summery of benefits from the proposed system.

  13. Technical And Economical FACTIBILITY To Apply A Combined Cycle

    International Nuclear Information System (INIS)

    Hernández Rangel, Elybe

    2017-01-01

    In the state of Falcon specifically in the peninsula of Paraguaná, there are two electric plants; GENEVAPCA and CADAFE. These companies are in charge of providing electrical power to the population, which is being affected by the increment of the population, plus the touristic development of the tax free zone. This reasons cause the systematic ration of the electrical power that as a consequence causes electrical interruptions for a long period of time. Due to this electrical plants can not cover the demand in its totality, there must be created alternative for usage of the electricity which would increment its production. The following thesis has an objective to analyze the technical and economical factibility to apply a combined cycle, with the purpose of increasing the electrical power supply and obtain a better thermodynamically performance. Such project was elaborated in four phases. The first phase contemplated the data collection related to the subject, obtaining important information to select the best option of the combined cycle. In the Second phase was executed the termination of the thermodynamically and energetically properties of the combined cycle, comparing the efficient of the simple cycle with the cycle mention before. As final phase, the project’s economical rentability was estimated for possible installation. (author)

  14. Technical comparison between Integrated Gasification Combined Cycle (IGCC) and Natural Gas Combined Cycle (NGCC) power plants

    Energy Technology Data Exchange (ETDEWEB)

    Ortiz, Pablo Andres Silva; Venturini, Osvaldo Jose; Lora, Electo Eduardo Silva [Federal University of Itajuba - UNIFEI, MG (Brazil). Excellence Group in Thermal Power and Distributed Generation - NEST], e-mails: osvaldo@unifei.edu.br, electo@unifei.edu.br

    2010-07-01

    Among the emerging clean coal technologies for power generation, Integrated Gasification Combined Cycle (IGCC) and Natural Gas Combined Cycle (NGCC) systems are receiving considerable attention as a potentially attractive option to reduce the emissions of greenhouse gases (GHG). The main reason is because these systems has high efficiency and low emissions in comparison with traditional power generation plants. Currently in IGCC and NGCC systems at demonstration stage is been considered to implement CCS technology. CO{sub 2} emissions can be avoided in a gasification-based power plant because by transferring almost all carbon compounds to CO{sub 2} through the water gas shift (WGS) reaction, then removing the CO{sub 2} before it is diluted in the combustion stage. The aim of this study is to compare the technical performance of an IGCC system that uses Brazilian coal and petroleum coke as fuel with a NGCC system, with the same fixed output power of 450 MW. The first section of this paper presents the plant configurations of IGCC systems. The following section presents an analysis of NGCC technology. (author)

  15. Thermodynamic Modeling for Open Combined Regenerative Brayton and Inverse Brayton Cycles with Regeneration before the Inverse Cycle

    Directory of Open Access Journals (Sweden)

    Lingen Chen

    2012-01-01

    Full Text Available A thermodynamic model of an open combined regenerative Brayton and inverse Brayton cycles with regeneration before the inverse cycle is established in this paper by using thermodynamic optimization theory. The flow processes of the working fluid with the pressure drops and the size constraint of the real power plant are modeled. There are 13 flow resistances encountered by the working fluid stream for the cycle model. Four of these, the friction through the blades and vanes of the compressors and the turbines, are related to the isentropic efficiencies. The remaining nine flow resistances are always present because of the changes in flow cross-section at the compressor inlet of the top cycle, regenerator inlet and outlet, combustion chamber inlet and outlet, turbine outlet of the top cycle, turbine outlet of the bottom cycle, heat exchanger inlet, and compressor inlet of the bottom cycle. These resistances associated with the flow through various cross-sectional areas are derived as functions of the compressor inlet relative pressure drop of the top cycle, and control the air flow rate, the net power output and the thermal efficiency. The analytical formulae about the power output, efficiency and other coefficients are derived with 13 pressure drop losses. It is found that the combined cycle with regenerator can reach higher thermal efficiency but smaller power output than those of the base combined cycle at small compressor inlet relative pressure drop of the top cycle.

  16. Optimum design and thermodynamic analysis of a gas turbine and ORC combined cycle with recuperators

    International Nuclear Information System (INIS)

    Cao, Yue; Gao, Yike; Zheng, Ya; Dai, Yiping

    2016-01-01

    Highlights: • A GT-ORC combined cycle with recuperators was designed. • The effect of the ORC turbine inlet pressure on the combined cycle was examined. • Toluene was a more suitable working fluid for the GT-ORC combined cycle. • The GT-ORC combined cycle performed better than the GT-Rankine combined cycle. • The sensitivity analysis to the ambient temperature was completed. - Abstract: Gas turbines are widely used in distributed power generation because of their high efficiency, low pollution and low operational cost. To further utilize the waste heat from gas turbines, an organic Rankine cycle (ORC) was proposed as the bottoming cycle for gas turbines in this paper. Two recuperators were coupled with the combined cycle to increase the thermal efficiency, and aromatics were chosen as the working fluid for the bottoming cycle. This paper focused on the optimum design and thermodynamic analysis of the gas turbine and ORC (GT-ORC) combined cycle. Results showed that the net power and thermal efficiency of the ORC increased with the ORC turbine inlet pressure and achieved optimum values at a specific pressure based on the optimum criteria. Furthermore, compared with the GT-Rankine combined cycle, the GT-ORC combined cycle had better thermodynamic performance. Toluene was a more suitable working fluid for the GT-ORC combined cycle. Moreover, ambient temperature sensitivity simulations concluded that the GT-ORC combined cycle had a maximum thermal efficiency and the combined cycle net power was mainly determined by the topping gas turbine cycle.

  17. Examination of C/C flat tile mock-ups with hypervapotron cooling after high heat flux testing

    International Nuclear Information System (INIS)

    Schedler, B.; Friedrich, T.; Traxler, H.; Eidenberger, E.; Scheu, C.; Clemens, H.; Pippan, R.; Escourbiac, F.

    2007-01-01

    Two C/C flat tile mock-ups with a hypervapotron cooling concept, have been successfully tested beyond ITER specification (3000 cycles at 15 MW/m 2 , 300 cycles at 20 MW/m 2 and 800-1000 cycles at 25 MW/m 2 ) in two electron beam testing facilities [F. Escourbiac, et al., Experimental simulation of cascade failure effect on tungsten and CFC flat tile armoured HHF components, Fusion Eng. Des., submitted for publication; F. Escourbiac, et al., A mature industrial solution for ITER divertor plasma facing components: hypervapotron cooling concept adapted to Tore Supra flat tile technology, Fusion Eng. Des. 75-79 (2005) 387-390]. Both mock-ups provide a SNECMA SEPCARB NS31 armour, which has been joined onto the CuCrZr heat sink by active metal casting (AMC) and electron beam welding (EBW). No tile detachment or sudden loss of single tiles has been observed; a cascade-like failure of flat tile armours was impossible to generate. At the maximum cyclic heat flux load of 25 MW/m 2 all tested tiles performed well except one, which revealed already a clear indication in the thermographic examination at the end of the manufacture. Visual examination and analysis of metallographic cuts of the remaining tiles demonstrated that the interface has not been altered. In addition, the shear strength of the C/C to copper joints measured after the high heat flux (HHF) test has been found to be still above the interlamellar shear strength of the used C/C material. The high resistance of the interface is explained by a modification of the C/C to copper joint interface due to silicon originating from the used C/C material

  18. Examination of C/C flat tile mock-ups with hypervapotron cooling after high heat flux testing

    Energy Technology Data Exchange (ETDEWEB)

    Schedler, B. [Technology Centre of PLANSEE SE, A-6600 Reutte (Austria)], E-mail: bertram.schedler@plansee.com; Friedrich, T.; Traxler, H. [Technology Centre of PLANSEE SE, A-6600 Reutte (Austria); Eidenberger, E.; Scheu, C.; Clemens, H. [Department of Physical Metallurgy and Materials Testing, University of Leoben, A-8700 Leoben (Austria); Pippan, R. [Austrian Academy of Sciences, Erich-Schmid-Institute of Material Science, A-8700 Leoben (Austria); Escourbiac, F. [Association EURATOM-CEA, DSM/DRFC, CEA Cadarache, F-13108 St. Paul Lez Durance (France)

    2007-04-15

    Two C/C flat tile mock-ups with a hypervapotron cooling concept, have been successfully tested beyond ITER specification (3000 cycles at 15 MW/m{sup 2}, 300 cycles at 20 MW/m{sup 2} and 800-1000 cycles at 25 MW/m{sup 2}) in two electron beam testing facilities [F. Escourbiac, et al., Experimental simulation of cascade failure effect on tungsten and CFC flat tile armoured HHF components, Fusion Eng. Des., submitted for publication; F. Escourbiac, et al., A mature industrial solution for ITER divertor plasma facing components: hypervapotron cooling concept adapted to Tore Supra flat tile technology, Fusion Eng. Des. 75-79 (2005) 387-390]. Both mock-ups provide a SNECMA SEPCARB NS31 armour, which has been joined onto the CuCrZr heat sink by active metal casting (AMC) and electron beam welding (EBW). No tile detachment or sudden loss of single tiles has been observed; a cascade-like failure of flat tile armours was impossible to generate. At the maximum cyclic heat flux load of 25 MW/m{sup 2} all tested tiles performed well except one, which revealed already a clear indication in the thermographic examination at the end of the manufacture. Visual examination and analysis of metallographic cuts of the remaining tiles demonstrated that the interface has not been altered. In addition, the shear strength of the C/C to copper joints measured after the high heat flux (HHF) test has been found to be still above the interlamellar shear strength of the used C/C material. The high resistance of the interface is explained by a modification of the C/C to copper joint interface due to silicon originating from the used C/C material.

  19. Analysis of Combined Cycle Power Plants with Chemical Looping Reforming of Natural Gas and Pre-Combustion CO2 Capture

    Directory of Open Access Journals (Sweden)

    Shareq Mohd Nazir

    2018-01-01

    Full Text Available In this paper, a gas-fired combined cycle power plant subjected to a pre-combustion CO2 capture method has been analysed under different design conditions and different heat integration options. The power plant configuration includes the chemical looping reforming (CLR of natural gas (NG, water gas shift (WGS process, CO2 capture and compression, and a hydrogen fuelled combined cycle to produce power. The process is denoted as a CLR-CC process. One of the main parameters that affects the performance of the process is the pressure for the CLR. The process is analysed at different design pressures for the CLR, i.e., 5, 10, 15, 18, 25 and 30 bar. It is observed that the net electrical efficiency increases with an increase in the design pressure in the CLR. Secondly, the type of steam generated from the cooling of process streams also effects the net electrical efficiency of the process. Out of the five different cases including the base case presented in this study, it is observed that the net electrical efficiency of CLR-CCs can be improved to 46.5% (lower heating value of NG basis by producing high-pressure steam through heat recovery from the pre-combustion process streams and sending it to the Heat Recovery Steam Generator in the power plant.

  20. A combined thermodynamic cycle used for waste heat recovery of internal combustion engine

    International Nuclear Information System (INIS)

    He, Maogang; Zhang, Xinxin; Zeng, Ke; Gao, Ke

    2011-01-01

    In this paper, we present a steady-state experiment, energy balance and exergy analysis of exhaust gas in order to improve the recovery of the waste heat of an internal combustion engine (ICE). Considering the different characteristics of the waste heat of exhaust gas, cooling water, and lubricant, a combined thermodynamic cycle for waste heat recovery of ICE is proposed. This combined thermodynamic cycle consists of two cycles: the organic Rankine cycle (ORC), for recovering the waste heat of lubricant and high-temperature exhaust gas, and the Kalina cycle, for recovering the waste heat of low-temperature cooling water. Based on Peng–Robinson (PR) equation of state (EOS), the thermodynamic parameters in the high-temperature ORC were calculated and determined via an in-house computer program. Suitable working fluids used in high-temperature ORC are proposed and the performance of this combined thermodynamic cycle is analyzed. Compared with the traditional cycle configuration, more waste heat can be recovered by the combined cycle introduced in this paper. -- Highlights: ► We study the energy balance of fuel in internal combustion engine. ► Heat recovery effect of exhaust gas is good when ICE is at a high-load condition. ► We propose a new combined thermodynamic cycle for waste heat of ICE. ► The combined cycle has a higher recovery efficiency than previous configurations.

  1. Optimization of the triple-pressure combined cycle power plant

    Directory of Open Access Journals (Sweden)

    Alus Muammer

    2012-01-01

    Full Text Available The aim of this work was to develop a new system for optimization of parameters for combined cycle power plants (CCGTs with triple-pressure heat recovery steam generator (HRSG. Thermodynamic and thermoeconomic optimizations were carried out. The objective of the thermodynamic optimization is to enhance the efficiency of the CCGTs and to maximize the power production in the steam cycle (steam turbine gross power. Improvement of the efficiency of the CCGT plants is achieved through optimization of the operating parameters: temperature difference between the gas and steam (pinch point P.P. and the steam pressure in the HRSG. The objective of the thermoeconomic optimization is to minimize the production costs per unit of the generated electricity. Defining the optimal P.P. was the first step in the optimization procedure. Then, through the developed optimization process, other optimal operating parameters (steam pressure and condenser pressure were identified. The developed system was demonstrated for the case of a 282 MW CCGT power plant with a typical design for commercial combined cycle power plants. The optimized combined cycle was compared with the regular CCGT plant.

  2. Learning Based on CC1 and CC4 Neural Networks

    OpenAIRE

    Kak, Subhash

    2017-01-01

    We propose that a general learning system should have three kinds of agents corresponding to sensory, short-term, and long-term memory that implicitly will facilitate context-free and context-sensitive aspects of learning. These three agents perform mututally complementary functions that capture aspects of the human cognition system. We investigate the use of CC1 and CC4 networks for use as models of short-term and sensory memory.

  3. A comparison of advanced heat recovery power cycles in a combined cycle for large ships

    DEFF Research Database (Denmark)

    Larsen, Ulrik; Sigthorsson, Oskar; Haglind, Fredrik

    2014-01-01

    Strong motivation exists within the marine sector to reduce fuel expenses and to comply with ever stricter emission regulations. Heat recovery can address both of these issues. The ORC (organic Rankine cycle), the Kalina cycle and the steam Rankine cycle have received the majority of the focus...... fluids possess high global warming potentials and hazard levels. It is concluded that the ORC has the greatest potential for increasing the fuel efficiency, and the combined cycle offers very high thermal efficiency. While being less efficient, the steam cycle has the advantages of being well proven...

  4. First North American 50 cc Total Artificial Heart Experience: Conversion from a 70 cc Total Artificial Heart.

    Science.gov (United States)

    Khalpey, Zain; Kazui, Toshinobu; Ferng, Alice S; Connell, Alana; Tran, Phat L; Meyer, Mark; Rawashdeh, Badi; Smith, Richard G; Sweitzer, Nancy K; Friedman, Mark; Lick, Scott; Slepian, Marvin J; Copeland, Jack G

    2016-01-01

    The 70 cc total artificial heart (TAH) has been utilized as bridge to transplant (BTT) for biventricular failure. However, the utilization of 70 cc TAH has been limited to large patients for the low output from the pulmonary as well as systemic vein compression after chest closure. Therefore, the 50 cc TAH was developed by SynCardia (Tucson, AZ) to accommodate smaller chest cavity. We report the first TAH exchange from a 70 to 50 cc due to a fit difficulty. The patient failed to be closed with a 70 cc TAH, although the patient met the conventional 70 cc TAH fit criteria. We successfully closed the chest with a 50 cc TAH.

  5. Thermodynamic assessment of a wind turbine based combined cycle

    International Nuclear Information System (INIS)

    Rabbani, M.; Dincer, I.; Naterer, G.F.

    2012-01-01

    Combined cycles use the exhaust gases released from a Gas Turbine (GT). Approximately 30–40% of the turbine shaft work is typically used to drive the Compressor. The present study analyzes a system that couples a Wind Turbine (WT) with a combined cycle. It demonstrates how a WT can be used to supply power to the Compressor in the GT cycle and pump fluid through a reheat Rankine cycle, in order to increase the overall power output. Three different configurations are discussed, namely high penetration, low penetration and wind power addition. In the case of a low electricity demand and high penetration configuration, extra wind power is used to compress air which can then be used in the low penetration configuration. During a high load demand, all the wind power is used to drive the pump and compressor and if required additional compressed air is supplied by a storage unit. The analysis shows that increasing the combustion temperature reduces the critical velocity and mass flow rate. Increases in wind speed reduce both energy and exergy efficiency of the overall system. -- Highlights: ► This study analyzes a system that couples a wind turbine with a combined power generation cycle. ► Surplus wind power is used to compress air, which is then stored and used at a later time. ► Increasing the pressure ratio will reduce the work ratio between the Rankine and Brayton cycles. ► A higher combustion temperature will increase the net work output, as well as the system energy and exergy efficiencies.

  6. Preliminary analysis of combined cycle of modular high-temperature gas cooled reactor

    International Nuclear Information System (INIS)

    Baogang, Z.; Xiaoyong, Y.; Jie, W.; Gang, Z.; Qian, S.

    2015-01-01

    Modular high-temperature gas cooled reactor (HTGR) is known as one of the most advanced nuclear reactors because of its inherent safety and high efficiency. The power conversion system of HTGR can be steam turbine based on Rankine cycle or gas turbine based on Brayton cycle respectively. The steam turbine system is mature and the gas turbine system has high efficiency but under development. The Brayton-Rankine combined cycle is an effective way to further promote the efficiency. This paper investigated the performance of combined cycle from the viewpoint of thermodynamics. The effect of non-dimensional parameters on combined cycle’s efficiency, such as temperature ratio, compression ratio, efficiency of compressor, efficiency of turbine, was analyzed. Furthermore, the optimal parameters to achieve highest efficiency was also given by this analysis under engineering constraints. The conclusions could be helpful to the design and development of combined cycle of HTGR. (author)

  7. Dreamweaver CC for dummies

    CERN Document Server

    Warner, Janine

    2013-01-01

    Turn your wonderful website dreams into robust realities with the help of Dreamweaver CC For Dummies! Creating dynamic websites is easy with Dreamweaver CC and this friendly, full-color guide. Updated for the latest version of Adobe's world-renowned web development tool, Dreamweaver CC For Dummies covers all aspects of creating websites, from understanding web design basics to using style sheets, integrating multimedia, implementing responsive design, testing and publishing your sites, and more. With the professional guidance of Web design expert Jan

  8. Operational Aspects of C/C++ Concurrency

    OpenAIRE

    Podkopaev, Anton; Sergey, Ilya; Nanevski, Aleksandar

    2016-01-01

    In this work, we present a family of operational semantics that gradually approximates the realistic program behaviors in the C/C++11 memory model. Each semantics in our framework is built by elaborating and combining two simple ingredients: viewfronts and operation buffers. Viewfronts allow us to express the spatial aspect of thread interaction, i.e., which values a thread can read, while operation buffers enable manipulation with the temporal execution aspect, i.e., determining the order in...

  9. Energy and exergy analysis of a closed Brayton cycle-based combined cycle for solar power tower plants

    International Nuclear Information System (INIS)

    Zare, V.; Hasanzadeh, M.

    2016-01-01

    Highlights: • A novel combined cycle is proposed for solar power tower plants. • The effects of solar subsystem and power cycle parameters are examined. • The proposed combined cycle yields exergy efficiencies of higher than 70%. • For the overall power plant exergy efficiencies of higher than 30% is achievable. - Abstract: Concentrating Solar Power (CSP) technology offers an interesting potential for future power generation and research on CSP systems of all types, particularly those with central receiver system (CRS) has been attracting a lot of attention recently. Today, these power plants cannot compete with the conventional power generation systems in terms of Levelized Cost of Electricity (LCOE) and if a competitive LCOE is to be reached, employing an efficient thermodynamic power cycle is deemed essential. In the present work, a novel combined cycle is proposed for power generation from solar power towers. The proposed system consists of a closed Brayton cycle, which uses helium as the working fluid, and two organic Rankine cycles which are employed to recover the waste heat of the Brayton cycle. The system is thermodynamically assessed from both the first and second law viewpoints. A parametric study is conducted to examine the effects of key operating parameters (including solar subsystem and power cycle parameters) on the overall power plant performance. The results indicate that exergy efficiencies of higher than 30% are achieved for the overall power plant. Also, according to the results, the power cycle proposed in this work has a better performance than the other investigated Rankine and supercritical CO_2 systems operating under similar conditions, for these types of solar power plants.

  10. Thermodynamic and economic analysis on geothermal integrated combined-cycle power plants

    International Nuclear Information System (INIS)

    Bettocchi, R.; Cantore, G.; Negri di Montenegro, G.; Gadda, E.

    1992-01-01

    This paper considers geothermal integrated power plants obtained matching a geothermal plant with, a two pressure level combined plant. The purpose of the paper is the evaluation of thermodynamic and economic aspects on geothermal integrated combined-cycle power plant and a comparison with conventional solutions. The results show that the integrated combined plant power is greater than the sum of combined cycle and geothermal plant powers considered separately and that the integrated plant can offer economic benefits reaching the 16% of the total capital required

  11. Hybrid solar central receiver for combined cycle power plant

    Science.gov (United States)

    Bharathan, Desikan; Bohn, Mark S.; Williams, Thomas A.

    1995-01-01

    A hybrid combined cycle power plant including a solar central receiver for receiving solar radiation and converting it to thermal energy. The power plant includes a molten salt heat transfer medium for transferring the thermal energy to an air heater. The air heater uses the thermal energy to preheat the air from the compressor of the gas cycle. The exhaust gases from the gas cycle are directed to a steam turbine for additional energy production.

  12. Get more control over your C/C++ service

    CERN Multimedia

    CERN. Geneva

    2015-01-01

    Are you looking for a way to better diagnose or monitor your C/C++ programs? Find out more about CMX - a neat, lightweight library (<32Kb) which targets this need. It allows to expose information from inside a process through a simple API, enabling pre-failure detection in combination with your favourite monitoring system.

  13. Thermodynamic analysis of an integrated solid oxide fuel cell cycle with a rankine cycle

    International Nuclear Information System (INIS)

    Rokni, Masoud

    2010-01-01

    Hybrid systems consisting of solid oxide fuel cells (SOFC) on the top of a steam turbine (ST) are investigated. The plants are fired by natural gas (NG). A desulfurization reactor removes the sulfur content in the fuel while a pre-reformer breaks down the heavier hydro-carbons. The pre-treated fuel enters then into the anode side of the SOFC. The remaining fuels after the SOFC stacks enter a burner for further burning. The off-gases are then used to produce steam for a Rankine cycle in a heat recovery steam generator (HRSG). Different system setups are suggested. Cyclic efficiencies up to 67% are achieved which is considerably higher than the conventional combined cycles (CC). Both adiabatic steam reformer (ASR) and catalytic partial oxidation (CPO) fuel pre-reformer reactors are considered in this investigation.

  14. Modeling of a combined cycle power plant

    International Nuclear Information System (INIS)

    Faridah Mohamad Idris

    2001-01-01

    The combined cycle power plant is a non-linear, closed loop system, which consists of high-pressure (HP) superheater, HP evaporator, HP economizer, low-pressure (LP) evaporator, HP drum, HP deaerator, condenser, HP and LP steam turbine and gas turbine. The two types of turbines in the plant for example the gas turbine and the HP and LP steam turbines operate concurrently to generate power to the plant. The exhaust gas which originate from the combustion chamber drives the gas turbine, after which it flows into the heat recovery steam generator (HRSG) to generate superheated steam to be used in driving the HP and LP steam turbines. In this thesis, the combined cycle power plant is modeled at component level using the physical method. Assuming that there is delay in transport, except for the gas turbine system, the mass and heat balances are applied on the components of the plant to derive the governing equations of the components. These time dependent equations, which are of first order differential types, are then solved for the mass and enthalpy of the components. The solutions were simulated using Matlab Simulink using measured plant data. Where necessary there is no plant data available, approximated data were used. The generalized regression neural networks are also used to generate extra sets of simulation data for the HRSG system. Comparisons of the simulation results with its corresponding plant data showed good agreements between the two and indicated that the models developed for the components could be used to represent the combined cycle power plant under study. (author)

  15. Basis set effects on coupled cluster benchmarks of electronically excited states: CC3, CCSDR(3) and CC2

    DEFF Research Database (Denmark)

    Silva-Junior, Mario R.; Sauer, Stephan P. A.; Schreiber, Marko

    2010-01-01

    Vertical electronic excitation energies and one-electron properties of 28 medium-sized molecules from a previously proposed benchmark set are revisited using the augmented correlation-consistent triple-zeta aug-cc-pVTZ basis set in CC2, CCSDR(3), and CC3 calculations. The results are compared...... to those obtained previously with the smaller TZVP basis set. For each of the three coupled cluster methods, a correlation coefficient greater than 0.994 is found between the vertical excitation energies computed with the two basis sets. The deviations of the CC2 and CCSDR(3) results from the CC3 reference...... values are very similar for both basis sets, thus confirming previous conclusions on the intrinsic accuracy of CC2 and CCSDR(3). This similarity justifies the use of CC2- or CCSDR(3)-based corrections to account for basis set incompleteness in CC3 studies of vertical excitation energies. For oscillator...

  16. Longitudinal study on transmission of MRSA CC398 within pig herds

    Directory of Open Access Journals (Sweden)

    Broens Els M

    2012-05-01

    Full Text Available Abstract Background Since the detection of MRSA CC398 in pigs in 2004, it has emerged in livestock worldwide. MRSA CC398 has been found in people in contact with livestock and thus has become a public health issue. Data from a large-scale longitudinal study in two Danish and four Dutch pig herds were used to quantify MRSA CC398 transmission rates within pig herds and to identify factors affecting transmission between pigs. Results Sows and their offspring were sampled at varying intervals during a production cycle. Overall MRSA prevalence of sows increased from 33% before farrowing to 77% before weaning. Overall MRSA prevalence of piglets was > 60% during the entire study period. The recurrent finding of MRSA in the majority of individuals indicates true colonization or might be the result of contamination. Transmission rates were estimated using a Susceptible-Infectious-Susceptible (SIS-model, which resulted in values of the reproduction ratio (R0 varying from 0.24 to 8.08. Transmission rates were higher in pigs treated with tetracyclins and β-lactams compared to untreated pigs implying a selective advantage of MRSA CC398 when these antimicrobials are used. Furthermore, transmission rates were higher in pre-weaning pigs compared to post-weaning pigs which might be explained by an age-related susceptibility or the presence of the sow as a primary source of MRSA CC398. Finally, transmission rates increased with the relative increase of the infection pressure within the pen compared to the total infection pressure, implying that within-pen transmission is a more important route compared to between-pen transmission and transmission through environmental exposure. Conclusion Our results indicate that MRSA CC398 is able to spread and persist in pig herds, resulting in an endemic situation. Transmission rates are affected by the use of selective antimicrobials and by the age of pigs.

  17. Rocket Based Combined Cycle (RBCC) engine inlet

    Science.gov (United States)

    2004-01-01

    Pictured is a component of the Rocket Based Combined Cycle (RBCC) engine. This engine was designed to ultimately serve as the near term basis for Two Stage to Orbit (TSTO) air breathing propulsion systems and ultimately a Single Stage to Orbit (SSTO) air breathing propulsion system.

  18. The History and Promise of Combined Cycle Engines for Access to Space Applications

    Science.gov (United States)

    Clark, Casie

    2010-01-01

    For the summer of 2010, I have been working in the Aerodynamics and Propulsion Branch at NASA Dryden Flight Research Center studying combined-cycle engines, a high speed propulsion concept. Combined cycle engines integrate multiple propulsion systems into a single engine capable of running in multiple modes. These different modes allow the engine to be extremely versatile and efficient in varied flight conditions. The two most common types of combined cycle engines are Rocket-Based Combined Cycle (RBCC) and Turbine Based Combined Cycle (TBCC). The RBCC essentially combines a rocket and ramjet engine, while the TBCC integrates a turbojet and ramjet1. These two engines are able to switch between different propulsion modes to achieve maximum performance. Extensive conceptual and ground test studies of RBCC engines have been undertaken; however, an RBCC engine has never, to my knowledge, been demonstrated in flight. RBCC engines are of particular interest because they could potentially power a reusable launch vehicle (RLV) into space. The TBCC has been flight tested and shown to be effective at reaching supersonic speeds, most notably in the SR-71 Blackbird2.

  19. Use of letrozole and clomiphene citrate combined with gonadotropins in clomiphene-resistant infertile women with polycystic ovary syndrome: a prospective study

    Directory of Open Access Journals (Sweden)

    Xi W

    2015-11-01

    Full Text Available Wenyan Xi,1 Shankun Liu,2 Hui Mao,1 Yongkang Yang,1 Xiang Xue,1 Xiaoning Lu1 1The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an City, Shaanxi, 2Taian City Central Hospital, Shandong, Taian, People’s Republic of China Background: Gonadotropin has been used to stimulate ovulation in clomiphene-resistant infertile women with polycystic ovary syndrome (PCOS, but it is associated with overstimulated cycles with the development of many follicles. The aim of the study was to evaluate the effectiveness and efficacy of letrozole and clomiphene citrate combined with human menopausal gonadotropin (HMG in CC-resistant infertile women with PCOS.Methods: Ninety-four women received the letrozole + HMG, 90 women received CC + HMG, and 71 women received HMG only. All women received one treatment regimen in one treatment cycle. All patients were given HMG 75 IU on alternate days daily starting on day 3 or day 7 until the day of administration of human chorionic gonadotropin.Results: The rate of monofollicular development was 80.2% in the letrozole + HMG group, 65.3% in the CC + HMG group, and 54.7% in the HMG-only group (P<0.05 for letrozole + HMG vs the other two groups. The number of developing follicles (≥14 mm follicles and the cycle cancellation rate due to ovarian hyperresponse were the lowest in the letrozole + HMG group, but the difference was not significant. The ovulation and pregnancy rate were similar among the three protocols. The HMG dose needed and the mean duration of treatment were significantly lower in the letrozole + HMG and CC + HMG groups compared with the HMG-only group.Conclusion: Letrozole in combination with HMG is an effective protocol for reducing the risks of hyperstimulation for ovarian induction in CC-resistant women with PCOS. This combination may be more appropriate in patients who are particularly sensitive to gonadotropin. Keywords: letrozole, clomiphene citrate, human menopausal gonadotropin

  20. Thermodynamic Analyses of Biomass Gasification Integrated Externally Fired, Post-Firing and Dual-Fuel Combined Cycles

    Directory of Open Access Journals (Sweden)

    Saeed Soltani

    2015-01-01

    Full Text Available In the present work, the results are reported of the energy and exergy analyses of three biomass-related processes for electricity generation: the biomass gasification integrated externally fired combined cycle, the biomass gasification integrated dual-fuel combined cycle, and the biomass gasification integrated post-firing combined cycle. The energy efficiency for the biomass gasification integrated post-firing combined cycle is 3% to 6% points higher than for the other cycles. Although the efficiency of the externally fired biomass combined cycle is the lowest, it has an advantage in that it only uses biomass. The energy and exergy efficiencies are maximized for the three configurations at particular values of compressor pressure ratios, and increase with gas turbine inlet temperature. As pressure ratio increases, the mass of air per mass of steam decreases for the biomass gasification integrated post-firing combined cycle, but the pressure ratio has little influence on the ratio of mass of air per mass of steam for the other cycles. The gas turbine exergy efficiency is the highest for the three configurations. The combustion chamber for the dual-fuel cycle exhibits the highest exergy efficiency and that for the post-firing cycle the lowest. Another benefit of the biomass gasification integrated externally fired combined cycle is that it exhibits the highest air preheater and heat recovery steam generator exergy efficiencies.

  1. Global spread of mouse-adapted Staphylococcus aureus lineages CC1, CC15, and CC88 among mouse breeding facilities.

    Science.gov (United States)

    Mrochen, Daniel M; Grumann, Dorothee; Schulz, Daniel; Gumz, Janine; Trübe, Patricia; Pritchett-Corning, Kathleen; Johnson, Sarah; Nicklas, Werner; Kirsch, Petra; Martelet, Karine; Brandt, Jens van den; Berg, Sabine; Bröker, Barbara M; Wiles, Siouxsie; Holtfreter, Silva

    2017-11-20

    We previously reported that laboratory mice from all global vendors are frequently colonized with Staphylococcus aureus (S. aureus). Genotyping of a snap sample of murine S. aureus isolates from Charles River, US, showed that mice were predominantly colonized with methicillin-sensitive CC88 strains. Here, we expanded our view and investigated whether laboratory mice from other global animal facilities are colonized with similar strains or novel S. aureus lineages, and whether the murine S. aureus isolates show features of host adaptation. In total, we genotyped 230 S. aureus isolates from various vendor facilities of laboratory mice around the globe (Charles River facilities in the USA, Canada, France, and Germany; another US facility) and university- or company-associated breeding facilities in Germany, China and New Zealand. Spa typing was performed to analyse the clonal relationship of the isolates. Moreover, multiplex PCRs were performed for human-specific virulence factors, the immune-evasion cluster (IEC) and superantigen genes (SAg). We found a total of 58 different spa types that clustered into 15 clonal complexes (CCs). Three of these S. aureus lineages had spread globally among laboratory mice and accounted for three quarters of the isolates: CC1 (13.5%), CC15 (14.3%), and CC88 (47.0%). Compared to human colonizing isolates of the same lineages, the murine isolates frequently lacked IEC genes and SAg genes on mobile genetic elements, implying long-term adaptation to the murine host. In conclusion, laboratory mice from various vendors are colonized with host-adapted S. aureus-strains of a few lineages, predominantly the CC88 lineage. S. aureus researchers must be cautioned that S. aureus colonization might be a relevant confounder in infection and vaccination studies and are therefore advised to screen their mice before experimentation. Copyright © 2017 The Authors. Published by Elsevier GmbH.. All rights reserved.

  2. Addition by subtraction in coupled-cluster theory: a reconsideration of the CC and CI interface and the nCC hierarchy.

    Science.gov (United States)

    Bartlett, Rodney J; Musiał, Monika

    2006-11-28

    The nCC hierarchy of coupled-cluster approximations, where n guarantees exactness for n electrons and all products of n electrons are derived and applied to several illustrative problems. The condition of exactness for n=2 defines nCCSD=2CC, with nCCSDT=3CC and nCCSDTQ=4CC being exact for three and four electrons. To achieve this, the minimum number of diagrams is evaluated, which is less than in the corresponding CC model. For all practical purposes, nCC is also the proper definition of a size-extensive CI. 2CC is also an orbitally invariant coupled electron pair approximation. The numerical results of nCC are close to those for the full CC variant, and in some cases are closer to the full CI reference result. As 2CC is exact for separated electron pairs, it is the natural zeroth-order approximation for the correlation problem in molecules with other effects introduced as these units start to interact. The nCC hierarchy of approximations has all the attractive features of CC including its size extensivity, orbital invariance, and orbital insensitivity, but in a conceptually appealing form suited to bond breaking, while being computationally less demanding. Excited states from the equation of motion (EOM-2CC) are also reported, which show results frequently approaching those of EOM-CCSDT.

  3. Economical impact of the BIG/CC technology use on the sugar cane industry

    Energy Technology Data Exchange (ETDEWEB)

    Queiroz, L.C. de; Nascimento, M.J.M. do [Brascep Engenharia Ltda., Rio de Janeiro (Brazil)

    1993-12-31

    The use of biomass as primary fuel for power and steam production using modern conversion technology such as the Biomass Integrated Gas Turbine/Combined Cycle (BIG/CC) has both technical and commercial potential. Brazil is implementing a BIG/CC Demonstration Plant to burn wood from eucalyptus short rotation forest and to test sugar cane bagasse as feedstock. The purpose of this project is to demonstrate the commercial viability of using biomass as a feedstock for power generation, its suitability for applications in developing countries, and the possibilities it offers for commercial activities in regions which currently have a low level of economic activities. The purpose of this paper is to show the potential applicability of this technology in the sugar cane industries of Developing Countries such as Brazil. The same quantity of sugar cane already processed in each sugar mill can produce sizable quantities of electric power at competitive costs, in addition to the traditional products -- sugar and/or ethanol, which will cause an economical impact, duplicating the revenue of these industries. The application of the BIG/CC technology in the Sugar Cane Industry may lead to the following scenario in developing countries: (1) power shall be produced at very competitive prices by specialized private firms associated with sugar mills; (2) plant sizes will be smaller -- 15 to 100 MW -- when based on biomass, a compared to large fossil fuel plants now prevailing; (3) ethanol and sugar production costs will be reduced due to more efficient and economical processes and due to the additional revenue from power production; (4) becoming more competitive with gasoline, ethanol production tends to increase, which will influence the automobile industry and improve the quality of life in big cities.

  4. Development Activities on Airbreathing Combined Cycle Engines

    Science.gov (United States)

    McArthur, J. Craig; Lyles, Garry (Technical Monitor)

    2000-01-01

    Contents include the following: Advanced reusable transportation(ART); aerojet and rocketdyne tests, RBCC focused concept flowpaths,fabricate flight weigh, test select components, document ART project, Istar (Integrated system test of an airbreathing rocket); combined cycle propulsion testbed;hydrocarbon demonstrator tracebility; Istar engine system and vehicle system closure study; and Istar project planning.

  5. A combined gas cooled nuclear reactor and fuel cell cycle

    Science.gov (United States)

    Palmer, David J.

    Rising oil costs, global warming, national security concerns, economic concerns and escalating energy demands are forcing the engineering communities to explore methods to address these concerns. It is the intention of this thesis to offer a proposal for a novel design of a combined cycle, an advanced nuclear helium reactor/solid oxide fuel cell (SOFC) plant that will help to mitigate some of the above concerns. Moreover, the adoption of this proposal may help to reinvigorate the Nuclear Power industry while providing a practical method to foster the development of a hydrogen economy. Specifically, this thesis concentrates on the importance of the U.S. Nuclear Navy adopting this novel design for its nuclear electric vessels of the future with discussion on efficiency and thermodynamic performance characteristics related to the combined cycle. Thus, the goals and objectives are to develop an innovative combined cycle that provides a solution to the stated concerns and show that it provides superior performance. In order to show performance, it is necessary to develop a rigorous thermodynamic model and computer program to analyze the SOFC in relation with the overall cycle. A large increase in efficiency over the conventional pressurized water reactor cycle is realized. Both sides of the cycle achieve higher efficiencies at partial loads which is extremely important as most naval vessels operate at partial loads as well as the fact that traditional gas turbines operating alone have poor performance at reduced speeds. Furthermore, each side of the cycle provides important benefits to the other side. The high temperature exhaust from the overall exothermic reaction of the fuel cell provides heat for the reheater allowing for an overall increase in power on the nuclear side of the cycle. Likewise, the high temperature helium exiting the nuclear reactor provides a controllable method to stabilize the fuel cell at an optimal temperature band even during transients helping

  6. The first DC performance test and analysis of CC conductor short sample at ASIPP conductor test facility

    International Nuclear Information System (INIS)

    Shi Yi; Wu Yu; Liu Huajun; Long Feng; Qian Li; Ren Zhibin; Li Shaolei; Liu Bo; Chen Jinglin

    2012-01-01

    Highlights: ► In this study the first DC performance experiments of ITER correction coil conductor short sample have been carried out in ASIPP test facility. ► A CC conductor short sample was fabricated and tested to confirm the capability of this test facility for qualification tests of CC conductors. ► There is no obvious impact of cycling on DC performance measurement. ► Those measured results of current sharing temperature are in agreement with the expected results from strand scaling - Abstract: The first DC performance experiments of ITER correction coil (CC) conductor short sample have been carried out in the conductor test facility of Institute of Plasma Physics, CAS (ASIPP) in January this year. Those experiments aim to investigate the DC performance of ITER CC conductor. The tested conductor short sample is bended as a half circle with the diameter of 270 mm to meet the background magnetic field shape. The half circle part of sample is longer than the final twist pitch. The current sharing temperature (T cs ) in the 3.86 T external magnetic field (B ex ), ≤12 kA could be measured including the critical current (I c ) run. There is no obvious impact of 1000 cycles on DC performance. Those measured T cs results are in agreement with the expected results from strand scaling.

  7. Combined cycle power plant with integrated low temperature heat (LOTHECO)

    International Nuclear Information System (INIS)

    Kakaras, E.; Doukelis, A.; Leithner, R.; Aronis, N.

    2004-01-01

    The major driver to enhance the efficiency of the simple gas turbine cycle has been the increase in process conditions through advancements in materials and cooling methods. Thermodynamic cycle developments or cycle integration are among the possible ways to further enhance performance. The current paper presents the possibilities and advantages from the LOTHECO natural gas-fired combined cycle concept. In the LOTHECO cycle, low-temperature waste heat or solar heat is used for the evaporation of injected water droplets in the compressed air entering the gas turbine's combustion chamber. Following a description of this innovative cycle, its advantages are demonstrated by comparison between different gas turbine power generation systems for small and large-scale applications, including thermodynamic and economic analysis. A commercial gas turbine (ALSTOM GT10C) has been selected and computed with the heat mass balance program ENBIPRO. The results from the energy analysis are presented and the features of each concept are discussed. In addition, the exergy analysis provides information on the irreversibilities of each process and suggested improvements. Finally, the economic analysis reveals that the combined cycle plant with a heavy-duty gas turbine is the most efficient and economic way to produce electricity at base load. However, on a smaller scale, innovative designs, such as the LOTHECO concept, are required to reach the same level of performance at feasible costs

  8. The inclusive decay b→cc{sup ¯}s revisited

    Energy Technology Data Exchange (ETDEWEB)

    Krinner, Fabian, E-mail: fabian-krinner@mytum.de [Physik-Department, Technische Universität München, James-Franck-Straße, 85748 Garching (Germany); Lenz, Alexander [Institute for Particle Physics and Phenomenology, Durham University, Durham DH1 3LE (United Kingdom); CERN – Theory Division, PH-TH, Case C01600, CH-1211 Geneva 23 (Switzerland); Rauh, Thomas [Physik-Department, Technische Universität München, James-Franck-Straße, 85748 Garching (Germany)

    2013-11-01

    The inclusive decay rate b→cc{sup ¯}s is enhanced considerably due to perturbative QCD corrections. We recalculate the dominant part of the NLO–QCD corrections, because they cannot be reconstructed from the literature and we give the full expressions in this paper. Further we include some previously neglected corrections originating from penguin diagrams. Combined with the impressive progress in the accurate determination of input parameters like charm quark mass, bottom quark mass and CKM parameters, this enables us to make a very precise prediction of the corresponding branching ratio Br(b→cc{sup ¯}s)=(23±2)%. This result is an essential ingredient for a model and even decay channel independent search for new physics effects in B decays.

  9. Comparison of Engine Cycle Codes for Rocket-Based Combined Cycle Engines

    Science.gov (United States)

    Waltrup, Paul J.; Auslender, Aaron H.; Bradford, John E.; Carreiro, Louis R.; Gettinger, Christopher; Komar, D. R.; McDonald, J.; Snyder, Christopher A.

    2002-01-01

    This paper summarizes the results from a one day workshop on Rocket-Based Combined Cycle (RBCC) Engine Cycle Codes held in Monterey CA in November of 2000 at the 2000 JANNAF JPM with the authors as primary participants. The objectives of the workshop were to discuss and compare the merits of existing Rocket-Based Combined Cycle (RBCC) engine cycle codes being used by government and industry to predict RBCC engine performance and interpret experimental results. These merits included physical and chemical modeling, accuracy and user friendliness. The ultimate purpose of the workshop was to identify the best codes for analyzing RBCC engines and to document any potential shortcomings, not to demonstrate the merits or deficiencies of any particular engine design. Five cases representative of the operating regimes of typical RBCC engines were used as the basis of these comparisons. These included Mach 0 sea level static and Mach 1.0 and Mach 2.5 Air-Augmented-Rocket (AAR), Mach 4 subsonic combustion ramjet or dual-mode scramjet, and Mach 8 scramjet operating modes. Specification of a generic RBCC engine geometry and concomitant component operating efficiencies, bypass ratios, fuel/oxidizer/air equivalence ratios and flight dynamic pressures were provided. The engine included an air inlet, isolator duct, axial rocket motor/injector, axial wall fuel injectors, diverging combustor, and exit nozzle. Gaseous hydrogen was used as the fuel with the rocket portion of the system using a gaseous H2/O2 propellant system to avoid cryogenic issues. The results of the workshop, even after post-workshop adjudication of differences, were surprising. They showed that the codes predicted essentially the same performance at the Mach 0 and I conditions, but progressively diverged from a common value (for example, for fuel specific impulse, Isp) as the flight Mach number increased, with the largest differences at Mach 8. The example cases and results are compared and discussed in this paper.

  10. Rocket Based Combined Cycle (RBCC) Engine

    Science.gov (United States)

    2004-01-01

    Pictured is an artist's concept of the Rocket Based Combined Cycle (RBCC) launch. The RBCC's overall objective is to provide a technology test bed to investigate critical technologies associated with opperational usage of these engines. The program will focus on near term technologies that can be leveraged to ultimately serve as the near term basis for Two Stage to Orbit (TSTO) air breathing propulsions systems and ultimately a Single Stage To Orbit (SSTO) air breathing propulsion system.

  11. Mutations in new cell cycle genes that fail to complement a multiply mutant third chromosome of Drosophila.

    Science.gov (United States)

    White-Cooper, H; Carmena, M; Gonzalez, C; Glover, D M

    1996-11-01

    We have simultaneously screened for new alleles and second site mutations that fail to complement five cell cycle mutations of Drosphila carried on a single third chromosome (gnu, polo, mgr, asp, stg). Females that are either transheterozygous for scott of the antartic (scant) and polo, or homozygous for scant produce embryos that show mitotic defects. A maternal effect upon embryonic mitoses is also seen in embryos derived from females transheterozygous with helter skelter (hsk) and either mgr or asp. cleopatra (cleo), fails to complement asp but is not uncovered by a deficiency for asp. The mitotic phenotype of larvae heterozygous for cleo and the multiple mutant chromosome is similar to weak alleles of asp, but there are no defects in male meiosis. Mutations that failed to complement stg fell into two complementation groups corresponding to stg and a new gene noose. Three of the new stg alleles are early zygotic lethals, whereas the fourth is a pharate adult lethal allele that affects both mitosis and meiosis. Mutations in noose fully complement a small deficiency that removes stg, but when placed in trans to certain stg alleles, result in late lethality and mitotic abnormalities in larval brains.

  12. Thermodynamic analysis of combined cycle under design/off-design conditions for its efficient design and operation

    International Nuclear Information System (INIS)

    Zhang, Guoqiang; Zheng, Jiongzhi; Xie, Angjun; Yang, Yongping; Liu, Wenyi

    2016-01-01

    Highlights: • Based on the PG9351FA gas turbine, two gas-steam combined cycles are redesigned. • Analysis of detailed off-design characteristics of the combined cycle main parts. • Suggestions for improving design and operation performance of the combined cycle. • Higher design efficiency has higher off-design efficiency in general PR range. • High pressure ratio combined cycles possess good off-design performance. - Abstract: To achieve a highly efficient design and operation of combined cycles, this study analyzed in detail the off-design characteristics of the main components of three combined cycles with different compressor pressure ratios (PRs) based on real units. The off-design model of combined cycle was built consisting of a compressor, a combustor, a gas turbine, and a heat recovery steam generator (HRSG). The PG9351FA unit is selected as the benchmark unit, on the basis of which the compressor is redesigned with two different PRs. Then, the design/off-design characteristics of the three units with different design PRs and the interactive relations between topping and bottoming cycles are analyzed with the same turbine inlet temperature (TIT). The results show that the off-design characteristics of the topping cycle affect dramatically the combined cycle performance. The variation range of the exergy efficiency of the topping cycle for the three units is between 11.9% and 12.4% under the design/off-design conditions. This range is larger than that of the bottoming cycle (between 9.2% and 9.5%). The HRSG can effectively recycle the heat/heat exergy of the gas turbine exhaust. Comparison among the three units shows that for a traditional gas-steam combined cycle, a high design efficiency results in a high off-design efficiency in the usual PR range. The combined cycle design efficiency of higher pressure ratio is almost equal to that of the PG9351FA, but its off-design efficiency is higher (maximum 0.42%) and the specific power decreases. As for

  13. Staphylococcus aureus CC398

    DEFF Research Database (Denmark)

    Price, Lance B.; Stegger, Marc; Hasman, Henrik

    2012-01-01

    Since its discovery in the early 2000s, methicillin-resistant Staphylococcus aureus (MRSA) clonal complex 398 (CC398) has become a rapidly emerging cause of human infections, most often associated with livestock exposure. We applied whole-genome sequence typing to characterize a diverse collection...... of CC398 isolates (n = 89), including MRSA and methicillin-susceptible S. aureus (MSSA) from animals and humans spanning 19 countries and four continents. We identified 4,238 single nucleotide polymorphisms (SNPs) among the 89 core genomes. Minimal homoplasy (consistency index = 0.9591) was detected...... among parsimony-informative SNPs, allowing for the generation of a highly accurate phylogenetic reconstruction of the CC398 clonal lineage. Phylogenetic analyses revealed that MSSA from humans formed the most ancestral clades. The most derived lineages were composed predominantly of livestock...

  14. The market outlook for integrated gasification combined cycle technology

    International Nuclear Information System (INIS)

    MacGregor, P.R.; Maslak, C.E.; Stoll, H.G.

    1991-01-01

    Integrated gasification combined cycle (IGCC) technology was developed in the 1970s and is now competitive with other coal fired technologies. Because it is a new technology, IGCC technology developments are continuing at a rapid pace and the trend in decreasing capital costs is similar to the same trend seen during the early decades of simple cycle gas turbines. Consequently, IGCC technology is expected to be even more economical during the mid and late 1990s than it is today. The objective of this paper is to provide an examination of the basic economic principles of IGCC technology and to illustrate the extent to which this technology is a viable least-cost generation addition technology. Moreover, key reliability and emissions issues are addressed in relation to the technology alternatives. This paper is organized to first review the IGCC technology and to contrast its reliability, emission, performance and cost data with the three key commercially proven technologies: simple cycle combustion turbines, combined cycle plants, and coal-fired steam plants. Economic screening curves are used to illustrate the need for a balanced generation expansion mix of technologies. The regional market opportunity for coal fueled technology orders in the US from 1992 through 2005 is presented

  15. Exergy analysis, parametric analysis and optimization for a novel combined power and ejector refrigeration cycle

    International Nuclear Information System (INIS)

    Dai Yiping; Wang Jiangfeng; Gao Lin

    2009-01-01

    A new combined power and refrigeration cycle is proposed, which combines the Rankine cycle and the ejector refrigeration cycle. This combined cycle produces both power output and refrigeration output simultaneously. It can be driven by the flue gas of gas turbine or engine, solar energy, geothermal energy and industrial waste heats. An exergy analysis is performed to guide the thermodynamic improvement for this cycle. And a parametric analysis is conducted to evaluate the effects of the key thermodynamic parameters on the performance of the combined cycle. In addition, a parameter optimization is achieved by means of genetic algorithm to reach the maximum exergy efficiency. The results show that the biggest exergy loss due to the irreversibility occurs in heat addition processes, and the ejector causes the next largest exergy loss. It is also shown that the turbine inlet pressure, the turbine back pressure, the condenser temperature and the evaporator temperature have significant effects on the turbine power output, refrigeration output and exergy efficiency of the combined cycle. The optimized exergy efficiency is 27.10% under the given condition.

  16. Numerical simulation of divergent rocket-based-combined-cycle performances under the flight condition of Mach 3

    Science.gov (United States)

    Cui, Peng; Xu, WanWu; Li, Qinglian

    2018-01-01

    Currently, the upper operating limit of the turbine engine is Mach 2+, and the lower limit of the dual-mode scramjet is Mach 4. Therefore no single power systems can operate within the range between Mach 2 + and Mach 4. By using ejector rockets, Rocket-based-combined-cycle can work well in the above scope. As the key component of Rocket-based-combined-cycle, the ejector rocket has significant influence on Rocket-based-combined-cycle performance. Research on the influence of rocket parameters on Rocket-based-combined-cycle in the speed range of Mach 2 + to Mach 4 is scarce. In the present study, influences of Mach number and total pressure of the ejector rocket on Rocket-based-combined-cycle were analyzed numerically. Due to the significant effects of the flight conditions and the Rocket-based-combined-cycle configuration on Rocket-based-combined-cycle performances, flight altitude, flight Mach number, and divergence ratio were also considered. The simulation results indicate that matching lower altitude with higher flight Mach numbers can increase Rocket-based-combined-cycle thrust. For another thing, with an increase of the divergent ratio, the effect of the divergent configuration will strengthen and there is a limit on the divergent ratio. When the divergent ratio is greater than the limit, the effect of divergent configuration will gradually exceed that of combustion on supersonic flows. Further increases in the divergent ratio will decrease Rocket-based-combined-cycle thrust.

  17. Exergy analysis of parabolic trough solar collectors integrated with combined steam and organic Rankine cycles

    International Nuclear Information System (INIS)

    Al-Sulaiman, Fahad A.

    2014-01-01

    Highlights: • As the solar irradiation increases, the exergetic efficiency increases. • The R134a combined cycle has best exergetic performance, 26%. • The R600a combined cycle has the lowest exergetic efficiency, 20%. • The main source of exergy destruction is the solar collector. • There is an exergetic improvement potential of 75% in the systems considered. - Abstract: In this paper, detailed exergy analysis of selected thermal power systems driven by parabolic trough solar collectors (PTSCs) is presented. The power is produced using either a steam Rankine cycle (SRC) or a combined cycle, in which the SRC is the topping cycle and an organic Rankine cycle (ORC) is the bottoming cycle. Seven refrigerants for the ORC were examined: R134a, R152a, R290, R407c, R600, R600a, and ammonia. Key exergetic parameters were examined: exergetic efficiency, exergy destruction rate, fuel depletion ratio, irreversibility ratio, and improvement potential. For all the cases considered it was revealed that as the solar irradiation increases, the exergetic efficiency increases. Among the combined cycles examined, the R134a combined cycle demonstrates the best exergetic performance with a maximum exergetic efficiency of 26% followed by the R152a combined cycle with an exergetic efficiency of 25%. Alternatively, the R600a combined cycle has the lowest exergetic efficiency, 20–21%. This study reveals that the main source of exergy destruction is the solar collector where more than 50% of inlet exergy is destructed, or in other words more than 70% of the total destructed exergy. In addition, more than 13% of the inlet exergy is destructed in the evaporator which is equivalent to around 19% of the destructed exergy. Finally, this study reveals that there is an exergetic improvement potential of 75% in the systems considered

  18. Combined Turbine and Cycle Optimization for Organic Rankine Cycle Power Systems—Part B

    DEFF Research Database (Denmark)

    La Seta, Angelo; Meroni, Andrea; Andreasen, Jesper Graa

    2016-01-01

    Organic Rankine cycle (ORC) power systems have recently emerged as promising solutions for waste heat recovery in low- and medium-size power plants. Their performance and economic feasibility strongly depend on the expander. The design process and efficiency estimation are particularly challenging...... due to the peculiar physical properties of the working fluid and the gas-dynamic phenomena occurring in the machine. Unlike steam Rankine and Brayton engines, organic Rankine cycle expanders combine small enthalpy drops with large expansion ratios. These features yield turbine designs with few highly...... is the preliminary design of an organic Rankine cycle turbogenerator to increase the overall energy efficiency of an offshore platform. For an increase in expander pressure ratio from 10 to 35, the results indicate up to 10% point reduction in expander performance. This corresponds to a relative reduction in net...

  19. CC-3 CAMAC crate controller for IBM PC

    International Nuclear Information System (INIS)

    Khare, A.N.; Ghodgaonkar, M.D.; Bairi, B.R.

    1991-01-01

    The specifications and implementation details of CAMAC Crate Controller CC-3 for IBM-PC compatible as a host computer, having capability to transfer high speed data with direct memory access (DMA) scheme and logic to execute CAMAC cycles directly from the crate controller, to implement the block algorithms specified in ANSI/IEEE Std. 683-1976 (Reaff-1981) are described. The maximum data transfer rate measured with 8 bit interface of PC-AT is 240K byte per second. This work is carried out under Seventh Five Year Plan Project on Modernisation of reactor Control Instrumentation and Development of CAMAC and Fastbus Instrumentation. (author). 9 refs., 5 figs., 4 appendixes

  20. Effects of letrozole in combination with low-dose intramuscular injection of human menopausal gonadotropin on ovulation and pregnancy of 156 patients with polycystic ovary syndrome.

    Science.gov (United States)

    Chen, Zhihua; Zhang, Mengzhen; Qiao, Yuhuan; Yang, Junjuan

    2016-01-01

    To explore the effects of letrozole (LE) in combination with low-dose intramuscular injection of human menopausal gonadotropin (HMG) on the ovulation induction and pregnancy of patients with polycystic ovary syndrome (PCOS). A total of 156 patients with PCOS infertility were randomly divided into an LE group, a clomiphene citrate (CC) group and an LE + HMG group (n= 52). LE and CC were orally taken according to the prescribed dosage on the 3rd-5th days of menstruation respectively, and 75 IU HMG was given through intramuscular injection. The ovulation induction parameters and pregnancy outcomes were observed. The number of ovulation cycle of LE + HMG group was significantly higher than that of LE group (χ 2 =8.451, Pmedication cycle of clinically pregnant patients was (2.9 ± 0.3) weeks, which was significantly shorter than those of CC and LE groups (F=17.241, Pmedication cycle and high clinical pregnancy rate, which is promising for treating patients with PCOS infertility.

  1. Theoretical analysis of a combined power and ejector refrigeration cycle using zeotropic mixture

    International Nuclear Information System (INIS)

    Yang, Xingyang; Zhao, Li; Li, Hailong; Yu, Zhixin

    2015-01-01

    Highlights: • A combined power and refrigeration cycle using zeotropic mixture is analyzed. • The cycle performances with different mixture compositions are compared. • Both exergy and parametric analysis of the combined cycle are conducted. - Abstract: A theoretical study on a combined power and ejector refrigeration cycle using zeotropic mixture isobutane/pentane is carried out. The performances of different mixture compositions are compared. An exergy analysis is conducted for the cycle. The result reveals that most exergy destruction happens in the ejector, where more than 40% exergy is lost. The heat exchange in generator causes the second largest exergy loss, larger than 28%. As the mass fraction of isobutane changes ranges from 100% to 0%, the relative exergy destruction of each component is also changing. And mixture isobutane/pentane (50/50) has the maximum exergy efficiency of 7.83%. The parametric analysis of generator temperature, condenser temperature and evaporator temperature for all the mixtures shows that, all these three thermodynamic parameters have a strong effect on the cycle performance.

  2. Maitake mushroom (Grifola frondosa) extract induces ovulation in patients with polycystic ovary syndrome: a possible monotherapy and a combination therapy after failure with first-line clomiphene citrate.

    Science.gov (United States)

    Chen, Jui-Tung; Tominaga, Kunihiko; Sato, Yoshiaki; Anzai, Hideo; Matsuoka, Ryo

    2010-12-01

    Insulin resistance is a prominent feature of polycystic ovary syndrome (PCOS), and insulin-sensitizing drugs are used to induce ovulation. Recently, it was reported that an extract from Maitake mushroom (Grifola frondosa) improves insulin resistance. The objective was to explore the effects of Maitake extract (SX-fraction: MSX) to induce ovulation in patients with PCOS in comparison with and in combination with clomiphene citrate (CC). We conducted an open trial with 80 patients with PCOS at three clinics in Japan. Seventy-two (72) new patients were randomly assigned to receive MSX or CC monotherapy for up to 12 weeks. Eighteen (18) patients who did not respond to MSX or CC were subjected to combination therapy of MSX and CC for up to 16 weeks. Eight (8) patients with documented history of failure to CC received combination therapy from the beginning. Ovulation was assessed by ultrasonography. Twenty-six (26) patients in the MSX group and 31 in the CC group were evaluated for ovulation. The ovulation rates for MSX and CC were as follows: 76.9% (20/26) and 93.5% (29/31), respectively by the patients (NS), and 41.7% (30/72) and 69.9% (58/83), respectively, by the cycles (p = 0.0006). In the combination therapy, 7 of 7 patients who failed in MSX monotherapy and 6 of 8 patients who failed in CC monotherapy showed ovulation. The present study suggests that MSX alone may induce ovulation in PCOS patients and may be useful as an adjunct therapy for patients who failed first-line CC treatment.

  3. A DAQ system for CAMAC controller CC/NET using DAQ-Middleware

    International Nuclear Information System (INIS)

    Inoue, E; Yasu, Y; Nakayoshi, K; Sendai, H

    2010-01-01

    DAQ-Middleware is a framework for the DAQ system which is based on RT-Middleware (Robot Technology Middleware) and dedicated to making DAQ systems. DAQ-Middleware has come into use as a one of the DAQ system framework for the next generation Particle Physics experiment at KEK in recent years. DAQ-Middleware comprises DAQ-Components with all necessary basic functions of the DAQ and is easily extensible. So, using DAQ-Middleware, you are able to construct easily your own DAQ system by combining these components. As an example, we have developed a DAQ system for a CC/NET [1] using DAQ-Middleware by the addition of GUI part and CAMAC readout part. The CC/NET, the CAMAC controller was developed to accomplish high speed read-out of CAMAC data. The basic design concept of CC/NET is to realize data taking through networks. So, it is consistent with the DAQ-Middleware concept. We show how it is convenient to use DAQ-Middleware.

  4. Possible Existence of (cc¯)–Nucleus Bound States

    International Nuclear Information System (INIS)

    Yokota, Akira; Oka, Makoto; Hiyama, Emiko

    2014-01-01

    Charmonium (cc¯) bound states in few-nucleon systems, 2 H, 4 He and 8 Be, are studied via Gaussian Expansion Method (GEM). We adopt a Gaussian potential as an effective (cc¯)–nucleon (N) interaction. The relation between two-body (cc¯)–N scattering length a cc¯−N and the binding energies B of (cc¯)–nucleus bound states are given. Recent lattice QCD data of a cc¯−N corresponds to B≃0.5 MeV for (cc¯)− 4 He and 2 MeV for (cc¯)− 8 Be in our results. (author)

  5. Energy-exergy analysis of compressor pressure ratio effects on thermodynamic performance of ammonia water combined cycle

    International Nuclear Information System (INIS)

    Mohtaram, Soheil; Chen, Wen; Zargar, T.; Lin, Ji

    2017-01-01

    Highlights: • Energy exergy analysis is conducted to find the effects of RP. • EES software is utilized to perform the detailed energy-exergy analyses. • Effects investigated through energy and exergy destruction, enthalpy, yields, etc. • Detailed results are reported showing the performance of gas and combined cycle. - Abstract: The purpose of this study is to investigate the effect of compressor pressure ratio (RP) on the thermodynamic performances of ammonia-water combined cycle through energy and exergy destruction, enthalpy temperature, yields, and flow velocity. The energy-exergy analysis is conducted on the ammonia water combined cycle and the Rankine cycle, respectively. Engineering Equation Solver (EES) software is utilized to perform the detailed analyses. Values and ratios regarding heat drop and exergy loss are presented in separate tables for different equipments. The results obtained by the energy-exergy analysis indicate that by increasing the pressure ratio compressor, exergy destruction of high-pressure compressors, intercooler, gas turbine and the special produced work of gas turbine cycle constantly increase and the exergy destruction of recuperator, in contrast, decreases continuously. In addition, the least amount of input fuel into the combined cycle is observed when the pressure ratio is no less than 7.5. Subsequently, the efficiency of the cycle in gas turbine and combined cycle is reduced because the fuel input into the combined cycle is increased.

  6. Combined Brayton-JT cycles with refrigerants for natural gas liquefaction

    Science.gov (United States)

    Chang, Ho-Myung; Park, Jae Hoon; Lee, Sanggyu; Choe, Kun Hyung

    2012-06-01

    Thermodynamic cycles for natural gas liquefaction with single-component refrigerants are investigated under a governmental project in Korea, aiming at new processes to meet the requirements on high efficiency, large capacity, and simple equipment. Based upon the optimization theory recently published by the present authors, it is proposed to replace the methane-JT cycle in conventional cascade process with a nitrogen-Brayton cycle. A variety of systems to combine nitrogen-Brayton, ethane-JT and propane-JT cycles are simulated with Aspen HYSYS and quantitatively compared in terms of thermodynamic efficiency, flow rate of refrigerants, and estimated size of heat exchangers. A specific Brayton-JT cycle is suggested with detailed thermodynamic data for further process development. The suggested cycle is expected to be more efficient and simpler than the existing cascade process, while still taking advantage of easy and robust operation with single-component refrigerants.

  7. Design of the randomized, Phase III, QUAZAR AML Maintenance trial of CC-486 (oral azacitidine) maintenance therapy in acute myeloid leukemia.

    Science.gov (United States)

    Roboz, Gail J; Montesinos, Pau; Selleslag, Dominik; Wei, Andrew; Jang, Jun-Ho; Falantes, Jose; Voso, Maria T; Sayar, Hamid; Porkka, Kimmo; Marlton, Paula; Almeida, Antonio; Mohan, Sanjay; Ravandi, Farhad; Garcia-Manero, Guillermo; Skikne, Barry; Kantarjian, Hagop

    2016-02-01

    Older patients with acute myeloid leukemia (AML) have worse rates of complete remission and shorter overall survival than younger patients. The epigenetic modifier CC-486 is an oral formulation of azacitidine with promising clinical activity in patients with AML in Phase I studies. The Phase III, randomized, double-blind, placebo-controlled QUAZAR AML Maintenance trial (CC-486-AML-001) examines CC-486 maintenance therapy (300 mg/day for 14 days of 28-day treatment cycles) for patients aged ≥55 years with AML in first complete remission. The primary end point is overall survival. Secondary end points include relapse-free survival, safety, health-related quality of life and healthcare resource utilization. This trial will investigate whether CC-486 maintenance can prolong remission and improve survival for older patients with AML.

  8. Substrate-Mediated C-C and C-H Coupling after Dehalogenation.

    Science.gov (United States)

    Kong, Huihui; Yang, Sha; Gao, Hongying; Timmer, Alexander; Hill, Jonathan P; Díaz Arado, Oscar; Mönig, Harry; Huang, Xinyan; Tang, Qin; Ji, Qingmin; Liu, Wei; Fuchs, Harald

    2017-03-15

    Intermolecular C-C coupling after cleavage of C-X (mostly, X = Br or I) bonds has been extensively studied for facilitating the synthesis of polymeric nanostructures. However, the accidental appearance of C-H coupling at the terminal carbon atoms would limit the successive extension of covalent polymers. To our knowledge, the selective C-H coupling after dehalogenation has not so far been reported, which may illuminate another interesting field of chemical synthesis on surfaces besides in situ fabrication of polymers, i.e., synthesis of novel organic molecules. By combining STM imaging, XPS analysis, and DFT calculations, we have achieved predominant C-C coupling on Au(111) and more interestingly selective C-H coupling on Ag(111), which in turn leads to selective synthesis of polymeric chains or new organic molecules.

  9. Numerical analysis and field study of time dependent exergy-energy of a gas-steam combined cycle

    Directory of Open Access Journals (Sweden)

    Barari Bamdad

    2012-01-01

    Full Text Available In this study, time dependent exergy analysis of the Fars Combined Power Plant Cycle has been investigated. Exergy analysis has been used for investigating each part of actual combined cycle by considering irreversibility from Apr 2006 to Oct 2010. Performance analysis has been done for each part by evaluating exergy destruction in each month. By using of exergy analysis, aging of each part has been evaluated respect to time duration. In addition, the rate of lost work for each month has been calculated and variation of this parameter has been considered as a function of aging rate. Finally, effects of exergy destruction of each part have been investigated on exergy destruction of whole cycle. Entire analysis has been done for Unit 3 and 4 of gas turbine cycle which combined by Unit B of steam cycle in Fars Combined Power Plant Cycle located in Fars province in Iran.

  10. Exergy analysis for combined regenerative Brayton and inverse Brayton cycles

    OpenAIRE

    Zelong Zhang, Lingen Chen, Fengrui Sun

    2012-01-01

    This paper presents the study of exergy analysis of combined regenerative Brayton and inverse Brayton cycles. The analytical formulae of exergy loss and exergy efficiency are derived. The largest exergy loss location is determined. By taking the maximum exergy efficiency as the objective, the choice of bottom cycle pressure ratio is optimized by detailed numerical examples, and the corresponding optimal exergy efficiency is obtained. The influences of various parameters on the exergy efficien...

  11. A combined thermodynamic cycle based on methanol dissociation for IC (internal combustion) engine exhaust heat recovery

    International Nuclear Information System (INIS)

    Fu, Jianqin; Liu, Jingping; Xu, Zhengxin; Ren, Chengqin; Deng, Banglin

    2013-01-01

    In this paper, a novel approach for exhaust heat recovery was proposed to improve IC (internal combustion) engine fuel efficiency and also to achieve the goal for direct usage of methanol as IC engine fuel. An open organic Rankine cycle system using methanol as working medium is coupled to IC engine exhaust pipe for exhaust heat recovery. In the bottom cycle, the working medium first undergoes dissociation and expansion processes, and is then directed back to IC engine as fuel. As the external bottom cycle and the IC engine main cycle are combined together, this scheme forms a combined thermodynamic cycle. Then, this concept was applied to a turbocharged engine, and the corresponding simulation models were built for both of the external bottom cycle and the IC engine main cycle. On this basis, the energy saving potential of this combined cycle was estimated by parametric analyses. Compared to the methanol vapor engine, IC engine in-cylinder efficiency has an increase of 1.4–2.1 percentage points under full load conditions, while the external bottom cycle can increase the fuel efficiency by 3.9–5.2 percentage points at the working pressure of 30 bar. The maximum improvement to the IC engine global fuel efficiency reaches 6.8 percentage points. - Highlights: • A combined thermodynamic cycle using methanol as working medium for IC engine exhaust heat recovery is proposed. • The external bottom cycle of exhaust heat recovery and IC engine working cycle are combined together. • IC engine fuel efficiency could be improved from both in-cylinder working cycle and external bottom cycle. • The maximum improvement to the IC engine global fuel efficiency reaches 6.8 percentage points at full load

  12. Performance analysis of solar parabolic trough collectors driven combined supercritical CO2 and organic Rankine cycle

    Directory of Open Access Journals (Sweden)

    Harwinder Singh

    2018-06-01

    Full Text Available In this paper, attempts have been made on the detailed energy and exergy analysis of solar parabolic trough collectors (SPTCs driven combined power plant. The combination of supercritical CO2 (SCO2 cycle and organic Rankine cycle (ORC integrated with SPTCs has been used to produce power, in which SCO2 cycle and ORC are arranged as a topping and bottoming cycle. Five organic working fluids like R134a, R1234yf, R407c, R1234ze, and R245fa were selected for a low temperature bottoming ORC. Five key exergetic parameters such as exergetic efficiency, exergy destruction rate, fuel depletion ratio, irreversibility ratio, and improvement potential were also examined. It was revealed that exergetic and thermal efficiency of all the combined cycles enhances as the direct normal irradiance increases from 0.5 kW/m2 to 0.95 kW/m2. As can be seen, R407c combined cycle has the maximum exergetic as well as thermal efficiency which is around 78.07% at 0.95 kW/m2 and 43.49% at 0.95 kW/m2, respectively. Alternatively, the R134a and R245fa combined cycle yields less promising results with the marginal difference in their performance. As inferred from the study that SCO2 turbine and evaporator has a certain amount of exergy destruction which is around 9.72% and 8.54% of the inlet exergy, and almost 38.10% of the total exergy destruction in case of R407c combined cycle. Moreover, the maximum amount of exergy destructed by the solar collector field which is more than 25% of the solar inlet exergy and around 54% of the total destructed exergy. Finally, this study concludes that R407c combined cycle has a minimum fuel depletion ratio of 0.2583 for a solar collector and possess the highest power output of 3740 kW. Keywords: Supercritical CO2cycle, Organic Rankine cycle, Exergetic performance, SPTCs, Organic fluids

  13. Parametric-based thermodynamic analysis of organic Rankine cycle as bottoming cycle for combined-cycle power plant

    International Nuclear Information System (INIS)

    Qureshi, S.; Memon, A.G.; Abbasi, A.F.

    2017-01-01

    In Pakistan, the thermal efficiency of the power plants is low because of a huge share of fuel energy is dumped into the atmosphere as waste heat. The ORC (Organic Rankine Cycle) has been revealed as one of the promising technologies to recover waste heat to enhance the thermal efficiency of the power plant. In current work, ORC is proposed as a second bottoming cycle for existing CCPP (Combined Cycle Power Plant). In order to assess the efficiency of the plant, a thermodynamic model is developed in the ESS (Engineering Equation Solver) software. The developed model is used for parametric analysis to assess the effects of various operating parameters on the system performance. The analysis of results shows that the integration of ORC system with existing CCPP system enhances the overall power output in the range of 150.5-154.58 MW with 0.24-5% enhancement in the efficiency depending on the operating conditions. During the parametric analysis of ORC, it is observed that inlet pressure of the turbine shows a significant effect on the performance of the system as compared to other operating parameters. (author)

  14. Illustrator CC digital classroom

    CERN Document Server

    Smith, Jennifer

    2013-01-01

    A complete training package lets you learn Adobe Illustrator CC at your own speed Adobe Illustrator is the leading drawing and illustration software used to create artwork for a variety of media. This book-and-DVD package provides 13 self-paced lessons that get you up to speed on the latest version of Illustrator (Creative Cloud). Step-by-step instructions in the full-color book are supported by video tutorials on the DVD. Together, these tools will help you learn Adobe Illustrator basics, essential skills, and all the new capabilities in Illustrator CC-in no time.  Includes step-by-step in

  15. Photoshop CC for dummies

    CERN Document Server

    Bauer, Peter

    2013-01-01

    Stretch your creativity beyond the cloud with this fully-updated Photoshop guide!Photoshop puts amazing design and photo-editing tools in the hands of creative professionals and hobbyists everywhere, and the latest version - Photoshop CC - is packed with even more powerful tools to help you manage and enhance your images. This friendly, full-color guide introduces you to the basics of Photoshop CC and provides clear explanations of the menus, panels, tools, options, and shortcuts you'll use the most. Plus, you'll learn valuable tips for fixing common photo flaws, improvin

  16. Combined heat and power considered as a virtual steam cycle heat pump

    International Nuclear Information System (INIS)

    Lowe, Robert

    2011-01-01

    The first aim of this paper is to shed light on the thermodynamic reasons for the practical pursuit of low temperature operation by engineers involved in the design and the operation of combined heat and power (CHP) and district heating (DH) systems. The paper shows that the steam cycle of a combined heat and power generator is thermodynamically equivalent to a conventional steam cycle generator plus an additional virtual steam cycle heat pump. This apparently novel conceptualisation leads directly to (i) the observed sensitivity of coefficient of performance of CHP to supply and return temperatures in associated DH systems, and (ii) the conclusion that the performance of CHP will tend to be significantly higher than real heat pumps operating at similar temperatures. The second aim, which is pursued more qualitatively, is to show that the thermodynamic performance advantages of CHP are consistent with the goal of deep, long-term decarbonisation of industrialised economies. As an example, estimates are presented, which suggest that CHP based on combined-cycle gas turbines with carbon capture and storage has the potential to reduce the carbon intensity of delivered heat by a factor of ∼30, compared with a base case of natural gas-fired condensing boilers. - Highlights: → Large-scale CHP systems are thermodynamically equivalent to virtual steam cycle heat pumps. → COPs of such virtual heat pumps are necessarily better than the Carnot limit for real heat pumps. → COPs can approach 9 for plant matched to district heating systems with flow temperatures of 90 deg. C. → CHP combined with CCGT and CCS can reduce the carbon intensity of delivered heat ∼30-fold.

  17. THERMODYNAMIC ANALYSIS AND SIMULATION OF A NEW COMBINED POWER AND REFRIGERATION CYCLE USING ARTIFICIAL NEURAL NETWORK

    Directory of Open Access Journals (Sweden)

    Hossein Rezvantalab

    2011-01-01

    Full Text Available In this study, a new combined power and refrigeration cycle is proposed, which combines the Rankine and absorption refrigeration cycles. Using a binary ammonia-water mixture as the working fluid, this combined cycle produces both power and refrigeration output simultaneously by employing only one external heat source. In order to achieve the highest possible exergy efficiency, a secondary turbine is inserted to expand the hot weak solution leaving the boiler. Moreover, an artificial neural network (ANN is used to simulate the thermodynamic properties and the relationship between the input thermodynamic variables on the cycle performance. It is shown that turbine inlet pressure, as well as heat source and refrigeration temperatures have significant effects on the net power output, refrigeration output and exergy efficiency of the combined cycle. In addition, the results of ANN are in excellent agreement with the mathematical simulation and cover a wider range for evaluation of cycle performance.

  18. Replacement of Neisseria meningitidis C cc11/ET-15 variant by a cc103 hypervirulent clone, Brazil 2005-2011.

    Science.gov (United States)

    Sardinha, Guilherme; Cordeiro, Soraia; Gomes, Erica; Romanelli, Cinthia; Andrade, Claudia; Reis, Joice; de Filippis, Ivano

    2013-08-01

    Outbreaks caused by serogroup C meningococci in the northeast region of Brazil from 2005 to 2011 were associated to the emergence of variant ET-15 of cc11, which has been replaced by cc103 from 2006 to date. The increase of cc103 should be closely monitored to prevent the spread of this clone to neighbouring regions. Copyright © 2013 Elsevier Inc. All rights reserved.

  19. Combined cycles and cogeneration with natural gas and alternative fuels

    International Nuclear Information System (INIS)

    Gusso, R.

    1992-01-01

    Since 1985 there has been a sharp increase world-wide in the sales of gas turbines. The main reasons for this are: the improved designs allowing better gas turbine and, thus, combined cycle efficiencies; the good fuel use indices in the the case of cogeneration; the versatility of the gas turbines even with poly-fuel plants; greatly limited exhaust emissions; and lower manufacturing costs and delivery times with respect to conventional plants. This paper after a brief discussion on the evolution in gas turbine applications in the world and in Italy, assesses their use and environmental impacts with fuels other than natural gas. The paper then reviews Italian efforts to develop power plants incorporating combined cycles and the gasification of coal, residual, and other low calorific value fuels

  20. A combined power cycle utilizing low-temperature waste heat and LNG cold energy

    International Nuclear Information System (INIS)

    Shi Xiaojun; Che Defu

    2009-01-01

    This paper has proposed a combined power system, in which low-temperature waste heat can be efficiently recovered and cold energy of liquefied natural gas (LNG) can be fully utilized as well. This system consists of an ammonia-water mixture Rankine cycle and an LNG power generation cycle, and it is modelled by considering mass, energy and species balances for every component and thermodynamic analyses are conducted. The results show that the proposed combined cycle has good performance, with net electrical efficiency and exergy efficiency of 33% and 48%, respectively, for a typical operating condition. The power output is equal to 1.25 MWh per kg of ammonia-water mixture. About 0.2 MW of electrical power for operating sea water pumps can be saved. Parametric analyses are performed for the proposed combined cycle to evaluate the effects of key factors on the performance of the proposed combined cycle through simulation calculations. Results show that a maximum net electrical efficiency can be obtained as the inlet pressure of ammonia turbine increases and the peak value increases as the ammonia mass fraction increases. Exergy efficiency goes up with the increased ammonia turbine inlet pressure. With the ammonia mass fraction increases, the net electrical efficiency increases, whereas exergy efficiency decreases. For increasing LNG turbine inlet pressure or heat source temperature, there is also a peak of net electrical efficiency and exergy efficiency. With the increase of LNG gas turbine outlet pressure, exergy efficiency increases while net electrical efficiency drops

  1. Waste-heat boiler application for the Vresova combined cycle plant

    Energy Technology Data Exchange (ETDEWEB)

    Vicek, Z. [Energoprojekt Praha, Prague (Czechoslovakia)

    1995-12-01

    This report describes a project proposal and implementation of two combined-cycle units of the Vresova Fuel Complex (PKV) with 2 x 200 MWe and heat supply. Participation of ENERGOPROJECT Praha a.s., in this project.

  2. Combination of IVF and IVM in naturally cycling women

    DEFF Research Database (Denmark)

    Tang-Pedersen, Mikael; Westergaard, Lars Grabow; Erb, Karin

    2012-01-01

    This study investigated the combination of an unstimulated IVF cycle with in-vitro maturation (IVM) of additional immature cumulus-oocyte-complexes (COC) from the same cycle collected at the same time as the spontaneous preovulatory follicle. This could potentially improve rates of embryo transfer...... and pregnancy/live births compared with conventional unstimulated IVF treatment and at the same time eliminate the risk of ovarian hyperstimulation syndrome. This prospective trial included 77 women with regular menstrual cycles. Age at inclusion was between 20 and 37 years. Results showed a retrieval rate...... between endometrial factors and IVM oocytes together with unknown competence of IVM embryos is suspected. For some time, there has been an increasing interest in mild approaches for fertility treatment, in particular IVF. In-vitro maturation (IVM) of immature eggs outside the ovaries followed by IVF...

  3. Exergy analysis for combined regenerative Brayton and inverse Brayton cycles

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Zelong; Chen, Lingen; Sun, Fengrui [College of Naval Architecture and Power, Naval University of Engineering, Wuhan 430033 (China)

    2012-07-01

    This paper presents the study of exergy analysis of combined regenerative Brayton and inverse Brayton cycles. The analytical formulae of exergy loss and exergy efficiency are derived. The largest exergy loss location is determined. By taking the maximum exergy efficiency as the objective, the choice of bottom cycle pressure ratio is optimized by detailed numerical examples, and the corresponding optimal exergy efficiency is obtained. The influences of various parameters on the exergy efficiency and other performances are analyzed by numerical calculations.

  4. The methylenetetrahydrofolate reductase c.c.677 C>T and c.c.1298 A>C polymorphisms in reproductive failures: Experience from an RSA and RIF study on a Polish population.

    Science.gov (United States)

    Nowak, Izabela; Bylińska, Aleksandra; Wilczyńska, Karolina; Wiśniewski, Andrzej; Malinowski, Andrzej; Wilczyński, Jacek R; Radwan, Paweł; Radwan, Michał; Barcz, Ewa; Płoski, Rafał; Motak-Pochrzęst, Hanna; Banasik, Małgorzata; Sobczyński, Maciej; Kuśnierczyk, Piotr

    2017-01-01

    Almost 1600 individuals from the Polish population were recruited to this study. Among them 319 were fertile couples, 289 were recurrent spontaneous abortion (RSA) couples, and 131 were in the group of recurrent implantation failure (RIF) following in vitro fertilization. The aim of this study was to evaluate the MTHFR c.c.677 C>T and c.c.1298 A>C polymorphisms' association with RSA and RIF. We used PCR-RFLP with HinfI (677 C>T) and MboII (1298 A>C) digestion. We observed a protective effect of the female AC genotype (OR = 0.64, p = 0.01) and the C allele (AC+CC genotypes; OR = 0.65, p = 0.009) against RSA. Moreover, 1298 AA/677 CT women were more frequent in RSA (31.14%) and RIF (25.20%) groups in comparison to fertile women (22.88%), although this difference was significant only in the case of RSA (p = 0.022, OR = 1.52). Male combined genotype analysis revealed no association with reproductive failure of their partners. Nevertheless, the female/male combination AA/AC of the 1298 polymorphism was more frequent in RSA couples (p = 0.049, OR = 1.49). However, the significant results became insignificant after Bonferroni correction. In addition, analysis of haplotypes showed significantly higher frequency of the C/C haplotype (1298 C/677 C) in the female control group than in the female RSA group (p = 0.03, OR = 0.77). Moreover, the association between elevated homocysteine (Hcy) level in plasma of RSA and RIF women and MTHFR polymorphisms was investigated but did not reveal significant differences. In conclusion, for clinical practice, it is better to check the homocysteine level in plasma and, if the Hcy level is increased, to recommend patients to take folic acid supplements rather than undergo screening of MTHFR for 1298 A>C and 677 C>T polymorphisms.

  5. Mononuclear Amido and Binuclear Imido Zirconium Complexes Supported by Dibenzotetraaza[14]annulene Ligands. X-ray Structure of [(Me(4)taa)Zr(&mgr;-NR)(2)Zr(NHR)(2)] (R = Bu(t) or 2,6-C(6)H(3)Me(2)).

    Science.gov (United States)

    Nikonov, Georgii I.; Blake, Alexander J.; Mountford, Philip

    1997-03-12

    Reaction of 2 equiv of Li[NH-2,6-C(6)H(3)R(2)] with [(Me(4)taa)ZrCl(2)] (Me(4)taaH(2) = tetramethyldibenzotetraaza[14]annulene) gives the bis(amido) derivatives [(Me(4)taa)Zr(NH-2,6-C(6)H(3)R(2))(2)] [R = Pr(i) (1) and Me (2)]. Addition of Me(4)taaH(2) to [Zr(N-2,6-C(6)H(3)Pr(i)(2))(NH-2,6-C(6)H(3)Pr(i)(2))(2)(py)(2)] also affords 1. The reaction of 2 equiv of aryl or alkyl amines H(2)NR with the bis(alkyl) complex [(Me(4)taa)Zr(CH(2)SiMe(3))(2)] is the most versatile method for preparing [(Me(4)taa)Zr(NHR)(2)] (R = 2,6-C(6)H(3)Pr(i)(2), 2,6-C(6)H(3)Me(2), Ph, or Bu(t)). Reaction of 1 equiv of Me(4)taaH(2) with the binuclear complexes [(Bu(t)NH)(2)Zr(&mgr;-NBu(t))(2)Zr(NHBu(t))(2)] or [(py)(HN-2,6-C(6)H(3)Me(2))(2)Zr(&mgr;-N-2,6-C(6)H(3)Me(2))(2)Zr(NH-2,6-C(6)H(3)Me(2))(2)(py)] gives the asymmetrically substituted derivatives [(Me(4)taa)Zr(&mgr;-NR)(2)Zr(NHR)(2)] [R = Bu(t) (6) or 2,6-C(6)H(3)Me(2) (8)], which have been crystallographically characterized.

  6. The reliability of integrated gasification combined cycle (IGCC) power generation units

    Energy Technology Data Exchange (ETDEWEB)

    Higman, C.; DellaVilla, S.; Steele, B. [Syngas Consultants Ltd. (United Kingdom)

    2006-07-01

    This paper presents two interlinked projects aimed at supporting the improvement of integrated gasification combined cycle (IGCC) reliability. The one project comprises the extension of SPS's existing ORAP (Operational Reliability Analysis Program) reliability, availability and maintainability (RAM) tracking technology from its existing base in natural gas open and combined cycle operations into IGCC. The other project is using the extended ORAP database to evaluate performance data from existing plants. The initial work has concentrated on evaluating public domain data on the performance of gasification based power and chemical plants. This is being followed up by plant interviews in some 20 plants to verify and expand the database on current performance. 23 refs., 8 figs., 2 tabs.

  7. Combined cycle power plants: technological prospects for improving the efficiency

    International Nuclear Information System (INIS)

    Lauri, R.

    2009-01-01

    The combined cycle power plants characteristics are better than one course open to a closed loop presenting an electrical efficiency close to 60% do not reach for gas turbine engines for power plants and conventional steam engines. [it

  8. Power and efficiency optimization for combined Brayton and inverse Brayton cycles

    International Nuclear Information System (INIS)

    Zhang Wanli; Chen Lingen; Sun Fengrui

    2009-01-01

    A thermodynamic model for open combined Brayton and inverse Brayton cycles is established considering the pressure drops of the working fluid along the flow processes and the size constraints of the real power plant using finite time thermodynamics in this paper. There are 11 flow resistances encountered by the gas stream for the combined Brayton and inverse Brayton cycles. Four of these, the friction through the blades and vanes of the compressors and the turbines, are related to the isentropic efficiencies. The remaining flow resistances are always present because of the changes in flow cross-section at the compressor inlet of the top cycle, combustion inlet and outlet, turbine outlet of the top cycle, turbine outlet of the bottom cycle, heat exchanger inlet, and compressor inlet of the bottom cycle. These resistances control the air flow rate and the net power output. The relative pressure drops associated with the flow through various cross-sectional areas are derived as functions of the compressor inlet relative pressure drop of the top cycle. The analytical formulae about the relations between power output, thermal conversion efficiency, and the compressor pressure ratio of the top cycle are derived with the 11 pressure drop losses in the intake, compression, combustion, expansion, and flow process in the piping, the heat transfer loss to the ambient, the irreversible compression and expansion losses in the compressors and the turbines, and the irreversible combustion loss in the combustion chamber. The performance of the model cycle is optimized by adjusting the compressor inlet pressure of the bottom cycle, the air mass flow rate and the distribution of pressure losses along the flow path. It is shown that the power output has a maximum with respect to the compressor inlet pressure of the bottom cycle, the air mass flow rate or any of the overall pressure drops, and the maximized power output has an additional maximum with respect to the compressor pressure

  9. Cycle-by-cycle variations in a spark ignition engine fueled with natural gas-hydrogen blends combined with EGR

    Energy Technology Data Exchange (ETDEWEB)

    Huang, Bin; Hu, Erjiang; Huang, Zuohua; Zheng, Jianjun; Liu, Bing; Jiang, Deming [State Key Laboratory of Multiphase Flow in Power Engineering, Xi' an Jiaotong University, 710049 Xi' an (China)

    2009-10-15

    Study of cycle-by-cycle variations in a spark ignition engine fueled with natural gas-hydrogen blends combined with exhaust gas recirculation (EGR) was conducted. The effects of EGR ratio and hydrogen fraction on engine cycle-by-cycle variations are analyzed. The results show that the cylinder peak pressure, the maximum rate of pressure rise and the indicated mean effective pressure decrease and cycle-by-cycle variations increase with the increase of EGR ratio. Interdependency between the above parameters and their corresponding crank angles of cylinder peak pressure is decreased with the increase of EGR ratio. For a given EGR ratio, combustion stability is promoted and cycle-by-cycle variations are decreased with the increase of hydrogen fraction in the fuel blends. Non-linear relationship is presented between the indicated mean effective pressure and EGR ratio. Slight influence of EGR ratio on indicated mean effective pressure is observed at low EGR ratios while large influence of EGR ratio on indicated mean effective pressure is demonstrated at high EGR ratios. The high test engine speed has lower cycle-by-cycle variations due to the enhancement of air flow turbulence and swirls in the cylinder. Increasing hydrogen fraction can maintain low cycle-by-cycle variations at high EGR ratios. (author)

  10. Are combined cycle plants being driven to zero discharge?

    International Nuclear Information System (INIS)

    Sinha, P.K.; Narula, R.G.; Weidinger, G.F.

    1991-01-01

    This paper discusses the water-related environmental issues of siting combined cycle plants, including availability of plant makeup water and wastewater discharge. The need for water treatment equipment for waste minimization, recycle, and/or zero discharge is discussed. The key water-related permit issues and preliminary design commitments are demonstrated via case histories

  11. Combined cycle plant controls retrofit case history

    International Nuclear Information System (INIS)

    Tenney, D.; Pieszchala, T.

    1991-01-01

    The Comanche Power Station, Public Service of Oklahoma's combined cycle generating facility, underwent a controls and operator panel retrofit at the end of 1988. The plant consists of two gas turbines, two heat recovery boilers and a steam turbine along with three generators. This paper examines the extent to which the original goals and specifications were met. Costs, operating principles and modifications since the original installation are discussed. Operating procedures are compared with the original system. The future of the plant is discussed and the impact on the power system grid is analyzed

  12. Predominantly elastic crack growth under combined creep-fatigue cycling

    International Nuclear Information System (INIS)

    Lloyd, G.J.

    1979-01-01

    A rationalization of the various observed effects of combined creep-fatigue cycling upon predominantly elastic fatigue-crack propagation in austenitic steel is presented. Existing and new evidence is used to show two main groups of behaviour: (i) material and cycling conditions which lead to modest increases (6-8 times) in the rate of crack growth are associated with relaxation-induced changes in the material deformation characteristics, and (ii) material and cycling conditions severe enough to generate internal fracture damage lead to significant (up to a factor of 30) increases in crack growth rate when compared with fast-cycling crack propagation rates at the same temperature. A working hypothesis is presented to show that the boundary between the two groups occurs when the scale of the nucleated creep damage is of the same magnitude as the crack tip opening displacement. This leads to the possibility of unstable crack advance. Creep crack growth rates are shown to provide an upper bound to creep-fatigue crack growth rates when crack advance is unstable. If the deformation properties only are affected by the creep-fatigue cycling then creep crack growth rates provide a lower bound. The role of intergranular oxygen corrosion in very low frequency crack growth tests is also briefly discussed. (author)

  13. Energy Materials Coordinating Committee (EMaCC)

    Energy Technology Data Exchange (ETDEWEB)

    1991-05-31

    This report summarizes EMaCC activities for fiscal year 1990 and describes the materials research programs of various offices and divisions within the department. The DOE Energy Materials Coordinating Committee (EMaCC) serves primarily to enhance coordination among the Department's materials programs and to further the effective use of materials expertise within the department. (JL)

  14. Performance analysis and binary working fluid selection of combined flash-binary geothermal cycle

    International Nuclear Information System (INIS)

    Zeyghami, Mehdi

    2015-01-01

    Performance of the combined flash-binary geothermal power cycle for geofluid temperatures between 150 and 250 °C is studied. A thermodynamic model is developed, and the suitable binary working fluids for different geofluid temperatures are identified from a list of thirty working fluid candidates, consisting environmental friendly refrigerants and hydrocarbons. The overall system exergy destruction and Vapor Expansion Ratio across the binary cycle turbine are selected as key performance indicators. The results show that for low-temperature heat sources using refrigerants as binary working fluids result in higher overall cycle efficiency and for medium and high-temperature resources, hydrocarbons are more suitable. For combined flash-binary cycle, secondary working fluids; R-152a, Butane and Cis-butane show the best performances at geofluid temperatures 150, 200 and 250 °C respectively. The overall second law efficiency is calculated as high as 0.48, 0.55 and 0.58 for geofluid temperatures equal 150, 200 and 250 °C respectively. The flash separator pressure found to has important effects on cycle operation and performance. Separator pressure dictates the work production share of steam and binary parts of the system. And there is an optimal separator pressure at which overall exergy destruction of the cycle achieves its minimum value. - Highlights: • Performance of the combined flash-binary geothermal cycle is investigated. • Thirty different fluids are screened to find the most suitable ORC working fluid. • Optimum cycle operation conditions presented for geofluids between 150 °C and 250 °C. • Refrigerants are more suitable for the ORC at geothermal sources temperature ≤200 °C. • Hydrocarbons are more suitable for the ORC at geothermal sources temperature >200 °C

  15. Thermal cycle efficiency of the indirect combined HTGR-GT power generation system

    Energy Technology Data Exchange (ETDEWEB)

    Muto, Yasushi [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1996-02-01

    High thermal efficiency of 50% could be expected in a power generation system coupling a high temperature gas-cooled reactor(HTGR) with a closed cycle gas turbine(GT). There are three candidate systems such as a direct cycle(DC), an indirect cycle(ICD) and an indirect combined cycle(IDCC). The IDCC could solve many problems in both the DC and the IDC and consists of a primary circuit and a secondary circuit where a topping cycle is a Brayton cycle and a bottoming cycle is a steam cycle. In this report, the thermal cycle efficiency of the IDCC is examined regarding configurations of components and steam pressure. It has been shown that there are two types of configurations, that is, a perfect cascade type and a semi-cascade one and the latter can be further classified into Case A, Case B and Case C. The conditions achieving the maximum thermal cycle efficiency were revealed for these cases. In addition, the optimum system configurations were proposed considering the thermal cycle efficiency, safety and plant arrangement. (author).

  16. Exergy optimization for a novel combination of organic Rankine cycles, Stirling cycle and direct expander turbines

    Science.gov (United States)

    Moghimi, Mahdi; Khosravian, Mohammadreza

    2018-06-01

    In this paper, a novel combination of organic Rankine cycles (ORCs), Stirling cycle and direct expander turbines is modeled and optimized using the genetic algorithm. The Exergy efficiency is considered as an objective function in the genetic algorithm. High efficiency is the main advantage of Stirling cycle, however, it needs nearly isothermal compressor and turbine. Therefore, an argon ORC and a R14 ORC are placed before and after the Striling cycle along with two expander turbines at the end of the line. Each component and cycle of the proposed plant in this article is verified by the previous works available in the literature and good agreement is achieved. The obtained results reveal that 27.98%, 20.86% and 12.90% of the total cold exergy are used by argon ORC, Stirling cycle and R14 ORC, respectively. Therefore, utilization of the Stirling cycle is a good idea for the LNG line cold exergy. The maximum exergy destruction occurs in the heat exchanger after the argon ORC (85.786 kJ/s per one kg/s LNG) due to the wasted cold exergy, which can be used for air conditioning systems in the plant. Finally, it would be shown that the maximum efficiency of the proposed plant is 54.25% and the maximum output power is 355.72 kW.

  17. Exergy optimization for a novel combination of organic Rankine cycles, Stirling cycle and direct expander turbines

    Science.gov (United States)

    Moghimi, Mahdi; Khosravian, Mohammadreza

    2018-01-01

    In this paper, a novel combination of organic Rankine cycles (ORCs), Stirling cycle and direct expander turbines is modeled and optimized using the genetic algorithm. The Exergy efficiency is considered as an objective function in the genetic algorithm. High efficiency is the main advantage of Stirling cycle, however, it needs nearly isothermal compressor and turbine. Therefore, an argon ORC and a R14 ORC are placed before and after the Striling cycle along with two expander turbines at the end of the line. Each component and cycle of the proposed plant in this article is verified by the previous works available in the literature and good agreement is achieved. The obtained results reveal that 27.98%, 20.86% and 12.90% of the total cold exergy are used by argon ORC, Stirling cycle and R14 ORC, respectively. Therefore, utilization of the Stirling cycle is a good idea for the LNG line cold exergy. The maximum exergy destruction occurs in the heat exchanger after the argon ORC (85.786 kJ/s per one kg/s LNG) due to the wasted cold exergy, which can be used for air conditioning systems in the plant. Finally, it would be shown that the maximum efficiency of the proposed plant is 54.25% and the maximum output power is 355.72 kW.

  18. Proposing a novel combined cycle for optimal exergy recovery of liquefied natural gas

    Energy Technology Data Exchange (ETDEWEB)

    Salimpour, M.R.; Zahedi, M.A. [Isfahan University of Technology (Iran, Islamic Republic of). Department of Mechanical Engineering

    2012-08-15

    The effective utilization of the cryogenic exergy associated with liquefied natural gas (LNG) vaporization is important. In this paper, a novel combined power cycle is proposed which utilizes LNG in different ways to enhance the power generation of a power plant. In addition to the direct expansion in the appropriate expander, LNG is used as a low-temperature heat sink for a middle-pressure gas cycle which uses nitrogen as working fluid. Also, LNG is used to cool the inlet air of an open Brayton gas turbine cycle. These measures are accomplished to improve the exergy recovery of LNG. In order to analyze the performance of the system, the influence of several key parameters such as pressure ratio of LNG turbine, ratio of the mass flow rate of LNG to the mass flow rate of air, pressure ratio of different compressors, LNG pressure and inlet pressure of nitrogen compressor, on the thermal efficiency and exergy efficiency of the offered cycle is investigated. Finally, the proposed combined cycle is optimized on the basis of first and second laws of thermodynamics. (orig.)

  19. Repression of CC16 by cigarette smoke (CS exposure.

    Directory of Open Access Journals (Sweden)

    Lingxiang Zhu

    Full Text Available Club (Clara Cell Secretory Protein (CCSP, or CC16 is produced mainly by non-ciliated airway epithelial cells including bronchiolar club cells and the change of its expression has been shown to associate with the progress and severity of Chronic Obstructive Pulmonary Disease (COPD. In an animal model, the lack of CC16 renders the animal susceptible to the tumorigenic effect of a major CS carcinogen. A recent population-based Tucson Epidemiological Study of Airway Obstructive Diseases (TESAOD has indicated that the low serum CC16 concentration is closely linked with the smoke-related mortality, particularly that driven by the lung cancer. However, the study of CC16 expression in well-defined smoke exposure models has been lacking, and there is no experimental support for the potential causal link between CC16 and CS-induced pathophysiological changes in the lung. In the present study, we have found that airway CC16 expression was significantly repressed in COPD patients, in monkey CS exposure model, and in CS-induced mouse model of COPD. Additionally, the lack of CC16 exacerbated airway inflammation and alveolar loss in the mouse model. Therefore, CC16 may play an important protective role in CS-related diseases.

  20. Dynamic simulation of combined cycle power plant cycling in the electricity market

    International Nuclear Information System (INIS)

    Benato, A.; Bracco, S.; Stoppato, A.; Mirandola, A.

    2016-01-01

    Highlights: • The flexibility of traditional power plants have become of primary importance. • Three dynamic models of the same single pressure HRSG are built. • The plant dynamic behaviour is predicted. • A lifetime calculation procedure is proposed and tested. • The drum lifetime reduction is estimated. - Abstract: The energy markets deregulation coupled with the rapid spread of unpredictable energy sources power units are stressing the necessity of improving traditional power plants flexibility. Cyclic operation guarantees high profits in the short term but, in the medium-long time, cause a lifetime reduction due to thermo-mechanical fatigue, creep and corrosion. In this context, Combined Cycle Power Plants are the most concerned in flexible operation problems. For this reason, two research groups from two Italian universities have developed a procedure to estimate the devices lifetime reduction with a particular focus on steam drums and superheaters/reheaters. To assess the lifetime reduction, it is essential to predict the thermodynamic variables trend in order to describe the plant behaviour. Therefore, the core of the procedure is the power plant dynamic model. At this purpose, in this paper, three different dynamic models of the same single pressure Combined Cycle Gas Turbine are presented. The models have been built using three different approaches and are used to simulate plant behaviour under real operating conditions. Despite these differences, the thermodynamic parameters time profiles are in good accordance as presented in the paper. At last, an evaluation of the drum lifetime reduction is performed.

  1. The ModelCC Model-Driven Parser Generator

    Directory of Open Access Journals (Sweden)

    Fernando Berzal

    2015-01-01

    Full Text Available Syntax-directed translation tools require the specification of a language by means of a formal grammar. This grammar must conform to the specific requirements of the parser generator to be used. This grammar is then annotated with semantic actions for the resulting system to perform its desired function. In this paper, we introduce ModelCC, a model-based parser generator that decouples language specification from language processing, avoiding some of the problems caused by grammar-driven parser generators. ModelCC receives a conceptual model as input, along with constraints that annotate it. It is then able to create a parser for the desired textual syntax and the generated parser fully automates the instantiation of the language conceptual model. ModelCC also includes a reference resolution mechanism so that ModelCC is able to instantiate abstract syntax graphs, rather than mere abstract syntax trees.

  2. Development of a Class for Multiple Precision Arithmetic in C/C++ Language

    OpenAIRE

    福田, 宏

    1998-01-01

    We have defined a floating-point variable of arbitrary length for a calculation of high precision and have developed a set of mathematical functions of it in C/C++ language. The variable and the functions are combined into a class in C++ language. In addition, the functions can be easily converted to those in FORTRAN language.

  3. $\\Xi_{cc}$ decays and properties

    CERN Multimedia

    Traill, Murdo Thomas

    2018-01-01

    The $\\Xi$ particles are baryons contains 2 constituent charm quarks in their structure which are expected to decay to high multi-body final states. The LHCb detector is ideally designed for studies of them due to its excellent particle identification and vertex reconstruction. Its capabilities in this area of physics was firmly demonstrated when LHCb announced the discovery of the first ever doubly charmed baryon, $\\Xi^{++}_{cc}$, in decays of $\\Xi^{++}_{cc} \\to \\Lambda^+K^-\\pi^+\\pi^+$ in 2017. This doubly charmed baryon was observed as a highly significant structure in the $\\Lambda^+_c K^-\\pi^+\\pi^+$ mass spectrum from proton-proton collision data recorded by the LHCb detector in Run2. A yield of 313 $\\pm$ 33 $\\Xi^{++}_{cc}$ candidates is measured and the local significances is in excess of 12 $\\sigma$ in the 13 TeV data. The properties of the peak suggest it is inconsistent with being a strongly decaying state. From the 13 TeV data, the mass is measured to be $3621.40\\pm 0.72(stat.) \\pm 0.27(syst....

  4. RB1CC1 activates RB1 pathway and inhibits proliferation and cologenic survival in human cancer.

    Directory of Open Access Journals (Sweden)

    Tokuhiro Chano

    2010-06-01

    Full Text Available RB1-inducible coiled-coil 1 (RB1CC1, also known as FIP200 plays a role in the enhancement of the RB1 pathway through the direct binding to a GC-rich region 201bp upstream (from the initiation ATG of the RB1 promoter. Here, we identified hSNF5 and p53 as the binding partners of RB1CC1 by immunoprecipitation and immunofluorescence assays. Interaction between these molecules and the RB1 pathway was analyzed by the assays of chromatin immunoprecipitation, luciferase-reporter, reverse transcription-polymerase chain reaction and immunoblot. The tumor growth suppression by RB1CC1 was evaluated by flow cytometry or by a cell growth assay. The nuclear RB1CC1 complex involving hSNF5 and/or p53 activated transcription of RB1, p16 and p21, and suppressed tumor cell growth. Furthermore, nuclear RB1CC1 expression significantly correlated with those of RB1 and p16 in breast cancer tissue in vivo, and the Ki-67 proliferation index was dependent on p53 as well as RB1CC1. The present study indicates that RB1CC1 together with hSNF5 and/or p53 enhances the RB1 pathway through transcriptional activation of RB1, p16 and p21. Evaluation of RB1CC1 expression combined with RB1 and p53 status is expected to provide useful information in clinical practice and future therapeutic strategies in breast cancer.

  5. Estimate for interstage water injection in air compressor incorporated into gas-turbine cycles and combined power plants cycles

    Science.gov (United States)

    Kler, A. M.; Zakharov, Yu. B.; Potanina, Yu. M.

    2017-05-01

    The objects of study are the gas turbine (GT) plant and combined cycle power plant (CCPP) with opportunity for injection between the stages of air compressor. The objective of this paper is technical and economy optimization calculations for these classes of plants with water interstage injection. The integrated development environment "System of machine building program" was a tool for creating the mathematic models for these classes of power plants. Optimization calculations with the criterion of minimum for specific capital investment as a function of the unit efficiency have been carried out. For a gas-turbine plant, the economic gain from water injection exists for entire range of power efficiency. For the combined cycle plant, the economic benefit was observed only for a certain range of plant's power efficiency.

  6. Global water cycle amplifying at less than the Clausius-Clapeyron rate

    OpenAIRE

    Skliris, Nikolaos; Zika, Jan D.; Nurser, George; Josey, Simon A.; Marsh, Robert

    2016-01-01

    A change in the cycle of water from dry to wet regions of the globe would have far reaching impact on humanity. As air warms, its capacity to hold water increases at the Clausius-Clapeyron rate (CC, approximately 7%?°C?1). Surface ocean salinity observations have suggested the water cycle has amplified at close to CC following recent global warming, a result that was found to be at odds with state-of the art climate models. Here we employ a method based on water mass transformation theory for...

  7. Optimization of advenced liquid natural gas-fuelled combined cycle machinery systems for a high-speed ferry

    DEFF Research Database (Denmark)

    Tveitaskog, Kari Anne; Haglind, Fredrik

    2012-01-01

    . Furthermore, practical and operational aspects of using these three machinery systems for a high-speed ferry are discussed. Two scenarios are evaluated. The first scenario evaluates the combined cycles with a given power requirement, optimizing the combined cycle while operating the gas turbine at part load...

  8. Thermal-CFD Analysis of Combined Solar-Nuclear Cycle Systems.

    Energy Technology Data Exchange (ETDEWEB)

    Fathi, Nima [Univ. of New Mexico, Albuquerque, NM (United States); McDaniel, Patrick [Univ. of New Mexico, Albuquerque, NM (United States); Vorobieff, Peter [Univ. of New Mexico, Albuquerque, NM (United States); de Oliveira, Cassiano [Univ. of New Mexico, Albuquerque, NM (United States); Rodriguez, Salvador B. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States); Aleyasin, Seyed Sobhan [Univ. of Manitoba (Canada)

    2015-09-01

    The aim of this paper is evaluating the efficiency of a novel combined solar-nuclear cycle. CFD-Thermal analysis is performed to apply the available surplus heat from the nuclear cycle and measure the available kinetic energy of air for the turbine of a solar chimney power plant system (SCPPS). The presented idea helps to decrease the thermal pollution and handle the water shortage supply for water plant by replacing the cooling tower by solar chimney power plant to get the surplus heat from the available warm air in the secondary loop of the reactor. By applying this idea to a typical 1000 MW nuclear power plant with a 0.33 thermal efficiency, we can increase it to 0.39.

  9. InDesign CC digital classroom

    CERN Document Server

    Smith, Christopher

    2013-01-01

    Learn the newest version of Adobe's premiere page design software-InDesign CC- with this complete package Written by a team of expert instructors, this complete book-and-DVD package teaches even the most inexperienced beginner how to design eye-popping layouts for brochures, magazines, e-books, and flyers. Step-by-step instructions in the full-color book are enhanced by video tutorials on the companion DVD. Thirteen self-paced lessons let you learn Adobe InDesign CC (Creative Cloud) at your own speed; it's like having your own personal tutor teaching you the hottest new version of this leadi

  10. First image from a combined positron emission tomography and field-cycled MRI system.

    Science.gov (United States)

    Bindseil, Geron A; Gilbert, Kyle M; Scholl, Timothy J; Handler, William B; Chronik, Blaine A

    2011-07-01

    Combining positron emission tomography and MRI modalities typically requires using either conventional MRI with a MR-compatible positron emission tomography system or a modified MR system with conventional positron emission tomography. A feature of field-cycled MRI is that all magnetic fields can be turned off rapidly, enabling the use of conventional positron emission tomography detectors based on photomultiplier tubes. In this demonstration, two photomultiplier tube-based positron emission tomography detectors were integrated with a field-cycled MRI system (0.3 T/4 MHz) by placing them into a 9-cm axial gap. A positron emission tomography-MRI phantom consisting of a triangular arrangement of positron-emitting point sources embedded in an onion was imaged in a repeating interleaved sequence of ∼1 sec MRI then 1 sec positron emission tomography. The first multimodality images from the combined positron emission tomography and field-cycled MRI system show no additional artifacts due to interaction between the systems and demonstrate the potential of this approach to combining positron emission tomography and MRI. Copyright © 2010 Wiley-Liss, Inc.

  11. Combined Turbine and Cycle Optimization for Organic Rankine Cycle Power Systems—Part A: Turbine Model

    Directory of Open Access Journals (Sweden)

    Andrea Meroni

    2016-04-01

    Full Text Available Axial-flow turbines represent a well-established technology for a wide variety of power generation systems. Compactness, flexibility, reliability and high efficiency have been key factors for the extensive use of axial turbines in conventional power plants and, in the last decades, in organic Rankine cycle power systems. In this two-part paper, an overall cycle model and a model of an axial turbine were combined in order to provide a comprehensive preliminary design of the organic Rankine cycle unit, taking into account both cycle and turbine optimal designs. Part A presents the preliminary turbine design model, the details of the validation and a sensitivity analysis on the main parameters, in order to minimize the number of decision variables in the subsequent turbine design optimization. Part B analyzes the application of the combined turbine and cycle designs on a selected case study, which was performed in order to show the advantages of the adopted methodology. Part A presents a one-dimensional turbine model and the results of the validation using two experimental test cases from literature. The first case is a subsonic turbine operated with air and investigated at the University of Hannover. The second case is a small, supersonic turbine operated with an organic fluid and investigated by Verneau. In the first case, the results of the turbine model are also compared to those obtained using computational fluid dynamics simulations. The results of the validation suggest that the model can predict values of efficiency within ± 1.3%-points, which is in agreement with the reliability of classic turbine loss models such as the Craig and Cox correlations used in the present study. Values similar to computational fluid dynamics simulations at the midspan were obtained in the first case of validation. Discrepancy below 12 % was obtained in the estimation of the flow velocities and turbine geometry. The values are considered to be within a

  12. Energy Materials Coordinating Committee (EMaCC), Fiscal year 1990

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    1991-05-31

    The DOE Energy Materials Coordinating Committee (EMaCC) serves primarily to enhance coordination among the Department's materials programs and to further the effective use of materials expertise within the Department. These functions are accomplished through the exchange of budgetary and planning information among program managers and through technical meetings/workshops on selected topics involving both DOE and major contractors. Four topical subcommittees are established and are continuing their own programs: Structural Ceramics, Electrochemical Technologies, Radioactive Waste Containment, and Superconductivity. In addition, the EMaCC aids in obtaining materialsrelated inputs for both intra- and inter-agency compilations. Membership in the EMaCC is open to any Department organizational unit; participants are appointed by Division or Office Directors. The current active membership is listed on the following four pages. The EMaCC reports to the Director of the Office of Energy Research in his capacity as overseer of the technical programs of the Department. This annual technical report is mandated by the EMaCC terms of reference. This report summarizes EMaCC activities for FY 1990 and describes the materials research programs of various offices and divisions within the Department. The Chairman of EMaCC for FY 1990 was Scott L. Richlen; the Executive Secretary was Dr. Jerry Smith.

  13. Unilateral Versus Bilateral Laparoscopic Ovarian Drilling Using Thermal Dose Adjusted According to Ovarian Volume in CC-Resistant PCOS, A Randomized Study.

    Science.gov (United States)

    El-Sayed, Mohamed Lotfy Mohamed; Ahmed, Mostafa Abdo; Mansour, Marwa Abdel Azim; Mansour, Shymma Abdel Azim

    2017-10-01

    This study aimed to evaluate the efficacy of unilateral laparoscopic ovarian drilling versus bilateral laparoscopic ovarian drilling with thermal dose adjusted according to ovarian volume in clomiphene citrate (CC)-resistant PCOS patients in terms of endocrine changes, menstrual cycle resumption, ovulation and pregnancy rates. This study was conducted in the Department of Obstetrics and Gynecology, Zagazig university hospitals. One hundred CC-resistant PCOS patients were divided into two groups. Group (I) (50 patients) underwent unilateral laparoscopic ovarian drilling with thermal dose adjusted according to ovarian volume (60 J/cm 3 of ovarian tissue), and group (II) (50 patients) underwent bilateral laparoscopic ovarian drilling using the same previously mentioned thermal dose. Endocrinal changes and menstrual cycle resumption were assessed within 8 weeks postoperatively, but the ovulation and pregnancy rates were estimated after 6-month follow-up period. There was no statistically significant difference between the two groups as regards demographic data ( p  > 0.05). As regards menstruation cycle resumption (62.5 vs. 81%) ( p  = 0.047), total ovulation rate (54.2 vs. 78.7%) ( p  = 0.011) and cumulative pregnancy rate (33.3 vs. 55.3%) ( p  = 0.031), there was statistically significant difference between both groups. After drilling, there were highly statistically significant decrease in the mean serum levels of luteinizing hormone (LH) and significant decrease in the mean serum levels of testosterone in both groups. Mean serum level of follicle stimulating hormone (FSH) did not change significantly in both groups after drilling. Bilateral laparoscopic ovarian drilling with thermal dose adjusted according to ovarian volume is more effective than the right-sided unilateral technique with thermal dose adjusted according to ovarian volume in terms of menstrual cycle resumption, ovulation and cumulative pregnancy rates in CC-resistant PCOS patients.

  14. Minimization of the LCA impact of thermodynamic cycles using a combined simulation-optimization approach

    International Nuclear Information System (INIS)

    Brunet, Robert; Cortés, Daniel; Guillén-Gosálbez, Gonzalo; Jiménez, Laureano; Boer, Dieter

    2012-01-01

    This work presents a computational approach for the simultaneous minimization of the total cost and environmental impact of thermodynamic cycles. Our method combines process simulation, multi-objective optimization and life cycle assessment (LCA) within a unified framework that identifies in a systematic manner optimal design and operating conditions according to several economic and LCA impacts. Our approach takes advantages of the complementary strengths of process simulation (in which mass, energy balances and thermodynamic calculations are implemented in an easy manner) and rigorous deterministic optimization tools. We demonstrate the capabilities of this strategy by means of two case studies in which we address the design of a 10 MW Rankine cycle modeled in Aspen Hysys, and a 90 kW ammonia-water absorption cooling cycle implemented in Aspen Plus. Numerical results show that it is possible to achieve environmental and cost savings using our rigorous approach. - Highlights: ► Novel framework for the optimal design of thermdoynamic cycles. ► Combined use of simulation and optimization tools. ► Optimal design and operating conditions according to several economic and LCA impacts. ► Design of a 10MW Rankine cycle in Aspen Hysys, and a 90kW absorption cycle in Aspen Plus.

  15. Minimization of the LCA impact of thermodynamic cycles using a combined simulation-optimization approach

    Energy Technology Data Exchange (ETDEWEB)

    Brunet, Robert; Cortes, Daniel [Departament d' Enginyeria Quimica, Escola Tecnica Superior d' Enginyeria Quimica, Universitat Rovira i Virgili, Campus Sescelades, Avinguda Paisos Catalans 26, 43007 Tarragona (Spain); Guillen-Gosalbez, Gonzalo [Departament d' Enginyeria Quimica, Escola Tecnica Superior d' Enginyeria Quimica, Universitat Rovira i Virgili, Campus Sescelades, Avinguda Paisos Catalans 26, 43007 Tarragona (Spain); Jimenez, Laureano [Departament d' Enginyeria Quimica, Escola Tecnica Superior d' Enginyeria Quimica, Universitat Rovira i Virgili, Campus Sescelades, Avinguda Paisos Catalans 26, 43007 Tarragona (Spain); Boer, Dieter [Departament d' Enginyeria Mecanica, Escola Tecnica Superior d' Enginyeria, Universitat Rovira i Virgili, Campus Sescelades, Avinguda Paisos Catalans 26, 43007, Tarragona (Spain)

    2012-12-15

    This work presents a computational approach for the simultaneous minimization of the total cost and environmental impact of thermodynamic cycles. Our method combines process simulation, multi-objective optimization and life cycle assessment (LCA) within a unified framework that identifies in a systematic manner optimal design and operating conditions according to several economic and LCA impacts. Our approach takes advantages of the complementary strengths of process simulation (in which mass, energy balances and thermodynamic calculations are implemented in an easy manner) and rigorous deterministic optimization tools. We demonstrate the capabilities of this strategy by means of two case studies in which we address the design of a 10 MW Rankine cycle modeled in Aspen Hysys, and a 90 kW ammonia-water absorption cooling cycle implemented in Aspen Plus. Numerical results show that it is possible to achieve environmental and cost savings using our rigorous approach. - Highlights: Black-Right-Pointing-Pointer Novel framework for the optimal design of thermdoynamic cycles. Black-Right-Pointing-Pointer Combined use of simulation and optimization tools. Black-Right-Pointing-Pointer Optimal design and operating conditions according to several economic and LCA impacts. Black-Right-Pointing-Pointer Design of a 10MW Rankine cycle in Aspen Hysys, and a 90kW absorption cycle in Aspen Plus.

  16. Search for the doubly charmed baryon $\\Xi_{cc}^+$

    CERN Document Server

    Aaij, R; Adinolfi, M; Adrover, C; Affolder, A; Ajaltouni, Z; Albrecht, J; Alessio, F; Alexander, M; Ali, S; Alkhazov, G; Alvarez Cartelle, P; Alves Jr, A A; Amato, S; Amerio, S; Amhis, Y; Anderlini, L; Anderson, J; Andreassen, R; Andrews, J E; Appleby, R B; Aquines Gutierrez, O; Archilli, F; Artamonov, A; Artuso, M; Aslanides, E; Auriemma, G; Baalouch, M; Bachmann, S; Back, J J; Badalov, A; Baesso, C; Balagura, V; Baldini, W; Barlow, R J; Barschel, C; Barsuk, S; Barter, W; Bauer, Th; Bay, A; Beddow, J; Bedeschi, F; Bediaga, I; Belogurov, S; Belous, K; Belyaev, I; Ben-Haim, E; Bencivenni, G; Benson, S; Benton, J; Berezhnoy, A; Bernet, R; Bettler, M -O; van Beuzekom, M; Bien, A; Bifani, S; Bird, T; Bizzeti, A; Bjørnstad, P M; Blake, T; Blanc, F; Blouw, J; Blusk, S; Bocci, V; Bondar, A; Bondar, N; Bonivento, W; Borghi, S; Borgia, A; Bowcock, T J V; Bowen, E; Bozzi, C; Brambach, T; van den Brand, J; Bressieux, J; Brett, D; Britsch, M; Britton, T; Brook, N H; Brown, H; Bursche, A; Busetto, G; Buytaert, J; Cadeddu, S; Callot, O; Calvi, M; Calvo Gomez, M; Camboni, A; Campana, P; Campora Perez, D; Carbone, A; Carboni, G; Cardinale, R; Cardini, A; Carranza-Mejia, H; Carson, L; Carvalho Akiba, K; Casse, G; Castillo Garcia, L; Cattaneo, M; Cauet, Ch; Cenci, R; Charles, M; Charpentier, Ph; Cheung, S -F; Chiapolini, N; Chrzaszcz, M; Ciba, K; Cid Vidal, X; Ciezarek, G; Clarke, P E L; Clemencic, M; Cliff, H V; Closier, J; Coca, C; Coco, V; Cogan, J; Cogneras, E; Collins, P; Comerma-Montells, A; Contu, A; Cook, A; Coombes, M; Coquereau, S; Corti, G; Couturier, B; Cowan, G A; Craik, D C; Cruz Torres, M; Cunliffe, S; Currie, R; D'Ambrosio, C; David, P; David, P N Y; Davis, A; De Bonis, I; De Bruyn, K; De Capua, S; De Cian, M; De Miranda, J M; De Paula, L; De Silva, W; De Simone, P; Decamp, D; Deckenhoff, M; Del Buono, L; Déléage, N; Derkach, D; Deschamps, O; Dettori, F; Di Canto, A; Dijkstra, H; Dogaru, M; Donleavy, S; Dordei, F; Dosil Suárez, A; Dossett, D; Dovbnya, A; Dupertuis, F; Durante, P; Dzhelyadin, R; Dziurda, A; Dzyuba, A; Easo, S; Egede, U; Egorychev, V; Eidelman, S; van Eijk, D; Eisenhardt, S; Eitschberger, U; Ekelhof, R; Eklund, L; El Rifai, I; Elsasser, Ch; Falabella, A; Färber, C; Farinelli, C; Farry, S; Ferguson, D; Fernandez Albor, V; Ferreira Rodrigues, F; Ferro-Luzzi, M; Filippov, S; Fiore, M; Fitzpatrick, C; Fontana, M; Fontanelli, F; Forty, R; Francisco, O; Frank, M; Frei, C; Frosini, M; Furfaro, E; Gallas Torreira, A; Galli, D; Gandelman, M; Gandini, P; Gao, Y; Garofoli, J; Garosi, P; Garra Tico, J; Garrido, L; Gaspar, C; Gauld, R; Gersabeck, E; Gersabeck, M; Gershon, T; Ghez, Ph; Gibson, V; Giubega, L; Gligorov, V V; Göbel, C; Golubkov, D; Golutvin, A; Gomes, A; Gorbounov, P; Gordon, H; Grabalosa Gándara, M; Graciani Diaz, R; Granado Cardoso, L A; Graugés, E; Graziani, G; Grecu, A; Greening, E; Gregson, S; Griffith, P; Grillo, L; Grünberg, O; Gui, B; Gushchin, E; Guz, Yu; Gys, T; Hadjivasiliou, C; Haefeli, G; Haen, C; Haines, S C; Hall, S; Hamilton, B; Hampson, T; Hansmann-Menzemer, S; Harnew, N; Harnew, S T; Harrison, J; Hartmann, T; He, J; Head, T; Heijne, V; Hennessy, K; Henrard, P; Hernando Morata, J A; van Herwijnen, E; Heß, M; Hicheur, A; Hicks, E; Hill, D; Hoballah, M; Hombach, C; Hulsbergen, W; Hunt, P; Huse, T; Hussain, N; Hutchcroft, D; Hynds, D; Iakovenko, V; Idzik, M; Ilten, P; Jacobsson, R; Jaeger, A; Jans, E; Jaton, P; Jawahery, A; Jing, F; John, M; Johnson, D; Jones, C R; Joram, C; Jost, B; Kaballo, M; Kandybei, S; Kanso, W; Karacson, M; Karbach, T M; Kenyon, I R; Ketel, T; Khanji, B; Kochebina, O; Komarov, I; Koopman, R F; Koppenburg, P; Korolev, M; Kozlinskiy, A; Kravchuk, L; Kreplin, K; Kreps, M; Krocker, G; Krokovny, P; Kruse, F; Kucharczyk, M; Kudryavtsev, V; Kurek, K; Kvaratskheliya, T; La Thi, V N; Lacarrere, D; Lafferty, G; Lai, A; Lambert, D; Lambert, R W; Lanciotti, E; Lanfranchi, G; Langenbruch, C; Latham, T; Lazzeroni, C; Le Gac, R; van Leerdam, J; Lees, J -P; Lefèvre, R; Leflat, A; Lefrançois, J; Leo, S; Leroy, O; Lesiak, T; Leverington, B; Li, Y; Li Gioi, L; Liles, M; Lindner, R; Linn, C; Liu, B; Liu, G; Lohn, S; Longstaff, I; Lopes, J H; Lopez-March, N; Lu, H; Lucchesi, D; Luisier, J; Luo, H; Lupton, O; Machefert, F; Machikhiliyan, I V; Maciuc, F; Maev, O; Malde, S; Manca, G; Mancinelli, G; Maratas, J; Marconi, U; Marino, P; Märki, R; Marks, J; Martellotti, G; Martens, A; Martín Sánchez, A; Martinelli, M; Martinez Santos, D; Martins Tostes, D; Martynov, A; Massafferri, A; Matev, R; Mathe, Z; Matteuzzi, C; Maurice, E; Mazurov, A; McCarthy, J; McNab, A; McNulty, R; McSkelly, B; Meadows, B; Meier, F; Meissner, M; Merk, M; Milanes, D A; Minard, M -N; Molina Rodriguez, J; Monteil, S; Moran, D; Morawski, P; Mordà, A; Morello, M J; Mountain, R; Mous, I; Muheim, F; Müller, K; Muresan, R; Muryn, B; Muster, B; Naik, P; Nakada, T; Nandakumar, R; Nasteva, I; Needham, M; Neubert, S; Neufeld, N; Nguyen, A D; Nguyen, T D; Nguyen-Mau, C; Nicol, M; Niess, V; Niet, R; Nikitin, N; Nikodem, T; Nomerotski, A; Novoselov, A; Oblakowska-Mucha, A; Obraztsov, V; Oggero, S; Ogilvy, S; Okhrimenko, O; Oldeman, R; Orlandea, M; Otalora Goicochea, J M; Owen, P; Oyanguren, A; Pal, B K; Palano, A; Palutan, M; Panman, J; Papanestis, A; Pappagallo, M; Parkes, C; Parkinson, C J; Passaleva, G; Patel, G D; Patel, M; Patrick, G N; Patrignani, C; Pavel-Nicorescu, C; Pazos Alvarez, A; Pearce, A; Pellegrino, A; Penso, G; Pepe Altarelli, M; Perazzini, S; Perez Trigo, E; Pérez-Calero Yzquierdo, A; Perret, P; Perrin-Terrin, M; Pescatore, L; Pesen, E; Pessina, G; Petridis, K; Petrolini, A; Phan, A; Picatoste Olloqui, E; Pietrzyk, B; Pilař, T; Pinci, D; Playfer, S; Plo Casasus, M; Polci, F; Polok, G; Poluektov, A; Polycarpo, E; Popov, A; Popov, D; Popovici, B; Potterat, C; Powell, A; Prisciandaro, J; Pritchard, A; Prouve, C; Pugatch, V; Puig Navarro, A; Punzi, G; Qian, W; Rachwal, B; Rademacker, J H; Rakotomiaramanana, B; Rangel, M S; Raniuk, I; Rauschmayr, N; Raven, G; Redford, S; Reichert, S; Reid, M M; dos Reis, A C; Ricciardi, S; Richards, A; Rinnert, K; Rives Molina, V; Roa Romero, D A; Robbe, P; Roberts, D A; Rodrigues, A B; Rodrigues, E; Rodriguez Perez, P; Roiser, S; Romanovsky, V; Romero Vidal, A; Rotondo, M; Rouvinet, J; Ruf, T; Ruffini, F; Ruiz, H; Ruiz Valls, P; Sabatino, G; Saborido Silva, J J; Sagidova, N; Sail, P; Saitta, B; Salustino Guimaraes, V; Sanmartin Sedes, B; Santacesaria, R; Santamarina Rios, C; Santovetti, E; Sapunov, M; Sarti, A; Satriano, C; Satta, A; Savrie, M; Savrina, D; Schiller, M; Schindler, H; Schlupp, M; Schmelling, M; Schmidt, B; Schneider, O; Schopper, A; Schune, M -H; Schwemmer, R; Sciascia, B; Sciubba, A; Seco, M; Semennikov, A; Senderowska, K; Sepp, I; Serra, N; Serrano, J; Seyfert, P; Shapkin, M; Shapoval, I; Shcheglov, Y; Shears, T; Shekhtman, L; Shevchenko, O; Shevchenko, V; Shires, A; Silva Coutinho, R; Sirendi, M; Skidmore, N; Skwarnicki, T; Smith, N A; Smith, E; Smith, E; Smith, J; Smith, M; Sokoloff, M D; Soler, F J P; Soomro, F; Souza, D; Souza De Paula, B; Spaan, B; Sparkes, A; Spradlin, P; Stagni, F; Stahl, S; Steinkamp, O; Stevenson, S; Stoica, S; Stone, S; Storaci, B; Straticiuc, M; Straumann, U; Subbiah, V K; Sun, L; Sutcliffe, W; Swientek, S; Syropoulos, V; Szczekowski, M; Szczypka, P; Szilard, D; Szumlak, T; T'Jampens, S; Teklishyn, M; Teodorescu, E; Teubert, F; Thomas, C; Thomas, E; van Tilburg, J; Tisserand, V; Tobin, M; Tolk, S; Tonelli, D; Topp-Joergensen, S; Torr, N; Tournefier, E; Tourneur, S; Tran, M T; Tresch, M; Tsaregorodtsev, A; Tsopelas, P; Tuning, N; Ubeda Garcia, M; Ukleja, A; Ustyuzhanin, A; Uwer, U; Vagnoni, V; Valenti, G; Vallier, A; Vazquez Gomez, R; Vazquez Regueiro, P; Vázquez Sierra, C; Vecchi, S; Velthuis, J J; Veltri, M; Veneziano, G; Vesterinen, M; Viaud, B; Vieira, D; Vilasis-Cardona, X; Vollhardt, A; Volyanskyy, D; Voong, D; Vorobyev, A; Vorobyev, V; Voß, C; Voss, H; Waldi, R; Wallace, C; Wallace, R; Wandernoth, S; Wang, J; Ward, D R; Watson, N K; Webber, A D; Websdale, D; Whitehead, M; Wicht, J; Wiechczynski, J; Wiedner, D; Wiggers, L; Wilkinson, G; Williams, M P; Williams, M; Wilson, F F; Wimberley, J; Wishahi, J; Wislicki, W; Witek, M; Wormser, G; Wotton, S A; Wright, S; Wu, S; Wyllie, K; Xie, Y; Xing, Z; Yang, Z; Yuan, X; Yushchenko, O; Zangoli, M; Zavertyaev, M; Zhang, F; Zhang, L; Zhang, W C; Zhang, Y; Zhelezov, A; Zhokhov, A; Zhong, L; Zvyagin, A

    2013-01-01

    A search for the doubly charmed baryon $\\Xi_{cc}^{+}$ in the decay mode $\\Xi_{cc}^{+} \\to \\Lambda_c^+ K^- \\pi^+$ is performed with a data sample, corresponding to an integrated luminosity of 0.65 fb$^{-1}$, of $pp$ collisions recorded at a centre-of-mass energy of 7 TeV. No significant signal is found in the mass range 3300--3800 MeV$/c^2$. Upper limits at the 95\\% confidence level on the ratio of the $\\Xi_{cc}^{+}$ production cross-section times branching fraction to that of the $\\Lambda_c^+$, $R$, are given as a function of the $\\Xi_{cc}^{+}$ mass and lifetime. The largest upper limits range from $R<1.5 \\times 10^{-2}$ for a lifetime of 100 fs to $R<3.9 \\times 10^{-4}$ for a lifetime of 400 fs.

  17. Research report for fiscal 1998. Basic research for promoting joint implementation, etc. (conversion of old coal-fired thermoelectric power plants in Poland into combined cycle plants); 1998 nendo chosa hokokusho. Poland sekitan karyoku hatsudensho (kyushiki) combined cycle eno tenkan

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    A project is discussed for modernization for energy efficiency enhancement and greenhouse gas reduction. The most effective way to reduce greenhouse gas in Poland is to totally replace the existing coal-fired power plants with natural gas combined cycle plants. Under this project, however, natural gas-fired power generation and integrated coal/brown coal gasification combined cycle power generation are both subjected to study. This is because the power plant modernization project is closely related to the fate of coal/brown coal industries which constitute the important industrial department of Poland. As for the earning rate of the project in case of natural gas-fired combined cycle power generation, the rate will be 13.2% even at the Kaweczyn station which is the highest in earning rate, and this fails to satisfy the project conditions. If integrated coal/brown gasification combined cycle power generation is chosen, the rate will be still lower. When the cost for greenhouse gas reduction is taken up, the Konin station exhibits the lowest of 9 dollars/tCO2, and the others 15-17 dollars/tCO2. When coal gas combined cycle is employed, the cost will be 3-4 times higher. (NEDO)

  18. An update technology for integrated biomass gasification combined cycle power plant

    International Nuclear Information System (INIS)

    Bhattacharya, P.; Dey, S.

    2014-01-01

    A discussion is presented on the technical analysis of a 6.4 M W_e integrated biomass gasification combined cycle (IBGCC) plant. It features three numbers of downdraft biomass gasifier systems with suitable gas clean-up trains, three numbers of internal combustion (IC) producer gas engines for producing 5.85 MW electrical power in open cycle and 550 kW power in a bottoming cycle using waste heat. Comparing with IC gas engine single cycle systems, this technology route increases overall system efficiency of the power plant, which in turn improves plant economics. Estimated generation cost of electricity indicates that mega-watt scale IBGCC power plants can contribute to good economies of scale in India. This paper also highlight's the possibility of activated carbon generation from the char, a byproduct of gasification process, and use of engine's jacket water heat to generate chilled water through VAM for gas conditioning. (author)

  19. Optimum operating conditions for a combined power and cooling thermodynamic cycle

    International Nuclear Information System (INIS)

    Sadrameli, S.M.; Goswami, D.Y.

    2007-01-01

    The combined production of thermal power and cooling with an ammonia-water based cycle proposed by Goswami is under intensive investigation. In the cycle under consideration, simultaneous cooling output is produced by expanding an ammonia-rich vapor in an expander to sub-ambient temperatures and subsequently heating the cool exhaust. When this mechanism for cooling production is considered in detail, it is apparent that the cooling comes at some expense to work production. To optimize this trade-off, a very specific coefficient-of-performance has been defined. In this paper, the simulation of the cycle was carried out in the process simulator ASPEN Plus. The optimum operating conditions have been found by using the Equation Oriented mode of the simulator and some of the results have been compared with the experimental data obtained from the cycle. The agreement between the two sets proves the accuracy of the optimization results

  20. Human and Swine Hosts Share Vancomycin-Resistant Enterococcus faecium CC17 and CC5 and Enterococcus faecalis CC2 Clonal Clusters Harboring Tn1546 on Indistinguishable Plasmids

    DEFF Research Database (Denmark)

    Freitas, Ana R.; Coque, Teresa M.; Novais, Carla

    2011-01-01

    clonally related Enterococcus faecium clonal complex 5 (CC5) isolates (17 sequence type 6 [ST6], 6 ST5, 5 ST185, 1 ST147, and 1 ST493) were obtained from feces of swine and healthy humans. This collection included isolates widespread among pigs of European Union (EU) countries since the mid-1990s. Each ST...... comprised isolates showing similar pulsed-field gel electrophoresis (PFGE) patterns (≤6 bands difference; >82% similarity). Some CC5 PFGE subtype strains from swine were indistinguishable from hospital vancomycin-resistant enterococci (VRE) causing infections. A truncated variant of Tn1546 (encoding...... resistance to vancomycin) and tcrB (coding for resistance to copper) were consistently located on 150- to 190-kb plasmids (rep(pLG1)). E. faecium CC17 (ST132) isolates from pig manure and two clinical samples showed identical PFGE profiles and contained a 60-kb mosaic plasmid (rep(Inc18) plus rep...

  1. A unified model of combined energy systems with different cycle modes and its optimum performance characteristics

    Energy Technology Data Exchange (ETDEWEB)

    Zhang Yue [Department of Physics and Institute of Theoretical Physics and Astrophysics, Xiamen University, Xiamen 361005 (China); College of Information Science and Engineering, Huaqiao University, Quanzhou 362021 (China); Hu, Weiqiang [Department of Physics and Institute of Theoretical Physics and Astrophysics, Xiamen University, Xiamen 361005 (China); Ou Congjie [College of Information Science and Engineering, Huaqiao University, Quanzhou 362021 (China); Chen Jincan [Department of Physics and Institute of Theoretical Physics and Astrophysics, Xiamen University, Xiamen 361005 (China)], E-mail: jcchen@xmu.edu.cn

    2009-06-15

    A unified model is presented for a class of combined energy systems, in which the systems mainly consist of a heat engine, a combustor and a counter-flow heat exchanger and the heat engine in the systems may have different thermodynamic cycle modes such as the Brayton cycle, Carnot cycle, Stirling cycle, Ericsson cycle, and so on. Not only the irreversibilities of the heat leak and finite-rate heat transfer but also the different cycle modes of the heat engine are considered in the model. On the basis of Newton's law, expressions for the overall efficiency and power output of the combined energy system with an irreversible Brayton cycle are derived. The maximum overall efficiency and power output and other relevant parameters are calculated. The general characteristic curves of the system are presented for some given parameters. Several interesting cases are discussed in detail. The results obtained here are very general and significant and can be used to discuss the optimal performance characteristics of a class of combined energy systems with different cycle modes. Moreover, it is significant to point out that not only the important conclusions obtained in Bejan's first combustor model and Peterson's general combustion driven model but also the optimal performance of a class of solar-driven heat engine systems can be directly derived from the present paper under some limit conditions.

  2. A unified model of combined energy systems with different cycle modes and its optimum performance characteristics

    International Nuclear Information System (INIS)

    Zhang Yue; Hu, Weiqiang; Ou Congjie; Chen Jincan

    2009-01-01

    A unified model is presented for a class of combined energy systems, in which the systems mainly consist of a heat engine, a combustor and a counter-flow heat exchanger and the heat engine in the systems may have different thermodynamic cycle modes such as the Brayton cycle, Carnot cycle, Stirling cycle, Ericsson cycle, and so on. Not only the irreversibilities of the heat leak and finite-rate heat transfer but also the different cycle modes of the heat engine are considered in the model. On the basis of Newton's law, expressions for the overall efficiency and power output of the combined energy system with an irreversible Brayton cycle are derived. The maximum overall efficiency and power output and other relevant parameters are calculated. The general characteristic curves of the system are presented for some given parameters. Several interesting cases are discussed in detail. The results obtained here are very general and significant and can be used to discuss the optimal performance characteristics of a class of combined energy systems with different cycle modes. Moreover, it is significant to point out that not only the important conclusions obtained in Bejan's first combustor model and Peterson's general combustion driven model but also the optimal performance of a class of solar-driven heat engine systems can be directly derived from the present paper under some limit conditions

  3. Les cardiopathies congenitales (cc) au Togo aspects ...

    African Journals Online (AJOL)

    The petrology of the. Follot (16.96%) and the CIA (06.25%) 112 patients have been transferred to foreign countries of which 74.10% Suisse 107 CC have been operated. The evolution has been favourable in 89.18%. In Togo, the discovery of the CC has been done lately posing therefore a problem of therapeutic choice.

  4. Thermoeconomic optimization of a combined-cycle solar tower power plant

    International Nuclear Information System (INIS)

    Spelling, James; Favrat, Daniel; Martin, Andrew; Augsburger, Germain

    2012-01-01

    A dynamic model of a pure-solar combined-cycle power plant has been developed in order to allow determination of the thermodynamic and economic performance of the plant for a variety of operating conditions and superstructure layouts. The model was then used for multi-objective thermoeconomic optimization of both the power plant performance and cost, using a population-based evolutionary algorithm. In order to examine the trade-offs that must be made, two conflicting objectives will be considered, namely minimal investment costs and minimal levelized electricity costs. It was shown that efficiencies in the region of 18–24% can be achieved, and this for levelized electricity costs in the region of 12–24 UScts/kWh e , depending on the magnitude of the initial investment, making the system competitive with current solar thermal technology. -- Highlights: ► Pure-solar combined-cycle studied using thermoeconomic tools. ► Multi-objective optimization conducted to determine Pareto-optimal power plant designs. ► Levelised costs between 12 and 24 UScts/kWhe predicted. ► Efficiencies between 18 and 24% predicted.

  5. A New Characterization of ACC0 and Probabilistic CC0

    DEFF Research Database (Denmark)

    Hansen, Kristoffer Arnsfelt; Koucký, Michal

    2010-01-01

    Barrington, Straubing & Thérien (1990) conjectured that the Boolean And function can not be computed by polynomial size constant depth circuits built from modular counting gates, i.e., by CC0 circuits. In this work we show that the And function can be computed by uniform probabilistic CC0 circuits...... that use only O(log n) random bits. This may be viewed as evidence contrary to the conjecture. As a consequence of our construction we get that all of ACC0 can be computed by probabilistic CC0 circuits that use only O(log n) random bits. Thus, if one were able to derandomize such circuits, one would obtain...... a collapse of circuit classes giving ACC0 = CC0. We present a derandomization of probabilistic CC0 circuits using And and Or gates to obtain ACC0 = And ο Or ο CC0 = Or ο And ο CC0. (And and Or gates of sublinear fan-in suffice in non-uniform setting.) Both these results hold for uniform as well as non...

  6. Thermodynamic performance analysis of a combined power cycle using low grade heat source and LNG cold energy

    International Nuclear Information System (INIS)

    Kim, Kyoung Hoon; Kim, Kyung Chun

    2014-01-01

    Thermodynamic analysis of a combined cycle using a low grade heat source and LNG cold energy was carried out. The combined cycle consisted of an ammonia–water Rankine cycle with and without regeneration and a LNG Rankine cycle. A parametric study was conducted to examine the effects of the key parameters, such as ammonia mass fraction, turbine inlet pressure, condensation temperature. The effects of the ammonia mass fraction on the temperature distributions of the hot and cold streams in heat exchangers were also investigated. The characteristic diagram of the exergy efficiency and heat transfer capability was proposed to consider the system performance and expenditure of the heat exchangers simultaneously. The simulation showed that the system performance is influenced significantly by the parameters with the ammonia mass fraction having largest effect. The net work output of the ammonia–water cycle may have a peak value or increase monotonically with increasing ammonia mass fraction, which depends on turbine inlet pressure or condensation temperature. The exergy efficiency may decrease or increase or have a peak value with turbine inlet pressure depending on the ammonia mass fraction. - Highlights: • Thermodynamic analysis was performed for a combined cycle utilizing LNG cold energy. • Ammonia–water Rankine cycle and LNG Rankine cycle was combined. • A parametric study was conducted to examine the effects of the key parameters. • Characteristics of the exergy efficiency and heat transfer capability were proposed. • The system performance was influenced significantly by the ammonia mass fraction

  7. Thermodynamic assessment of impact of inlet air cooling techniques on gas turbine and combined cycle performance

    International Nuclear Information System (INIS)

    Mohapatra, Alok Ku; Sanjay

    2014-01-01

    The article is focused on the comparison of impact of two different methods of inlet air cooling (vapor compression and vapor absorption cooling) integrated to a cooled gas turbine based combined cycle plant. Air-film cooling has been adopted as the cooling technique for gas turbine blades. A parametric study of the effect of compressor pressure ratio, compressor inlet temperature (T i , C ), turbine inlet temperature (T i , T ), ambient relative humidity and ambient temperature on performance parameters of plant has been carried out. Optimum T i , T corresponding to maximum plant efficiency of combined cycle increases by 100 °C due to the integration of inlet air cooling. It has been observed that vapor compression cooling improves the efficiency of gas turbine cycle by 4.88% and work output by 14.77%. In case of vapor absorption cooling an improvement of 17.2% in gas cycle work output and 9.47% in gas cycle efficiency has been observed. For combined cycle configuration, however, vapor compression cooling should be preferred over absorption cooling in terms of higher plant performance. The optimum value of compressor inlet temperature has been observed to be 20 °C for the chosen set of conditions for both the inlet air cooling schemes. - Highlights: • Inlet air cooling improves performance of cooled gas turbine based combined cycle. • Vapor compression inlet air cooling is superior to vapor absorption inlet cooling. • For every turbine inlet temperature, there exists an optimum pressure ratio. • The optimum compressor inlet temperature is found to be 293 K

  8. Performance evaluation of combined ejector LiBr/H2O absorption cooling cycle

    Directory of Open Access Journals (Sweden)

    Hasan Sh. Majdi

    2016-03-01

    Full Text Available The objective of this work is to develop a computer simulation program to evaluate the performance of solar-assited combined ejector absorption (single-effect cooling system using LiBr/H2O as a working fluid and operating under steady-state conditions. The ejector possess no moving parts and is simple and reliable, which makes it attractive for combination with single-stage absorption cycle for further improvement to the system's performance. In this research, improvement to the system is achieved by utilizing the potential kinetic energy of the ejector to enhance refrigeration efficiency. The effects of the entrainment ratio of the ejector, operating temperature, on the thermal loads, and system performance have been investigated. The results showed that the evaporator and condenser loads, post-addition of the ejector, is found to be permanently higher than that in the basic cycle, which indicates a significant enhancement of the proposed cycle and the cooling capacity of the system increasing with the increase in evaporator temperature and entrainment ratio. The COP of the modified cycle is improved by up to 60 % compared with that of the basic cycle at the given condition. This process stabilizes the refrigeration system, enhanced its function, and enabled the system to work under higher condenser temperatures.

  9. Biocide Susceptibility of Staphylococcus aureus CC398 and CC30 Isolates from Pigs and Identification of the Biocide Resistance Genes, qacG and qacC

    DEFF Research Database (Denmark)

    Seier-Petersen, Maria Amalie; Nielsen, Lene Nørby; Ingmer, Hanne

    2015-01-01

    Objectives: Methicillin-resistant Staphylococcus aureus (MRSA), in particular clonal complex (CC) 398, is increasingly found in livestock. Recently, MRSA CC30 was identified in Danish pigs. We determined the susceptibility of porcine S. aureus isolates of CC398 and CC30 to disinfectants used in pig......)-encoding virulence factors were investigated. Methods: Susceptibilities to biocides and antimicrobial agents of 79 porcine S. aureus isolates were determined by the microdilution method. Isolates comprised 21 methicillin-sensitive S. aureus (MSSA) and 40 MRSA isolates belonging to CC398 and 13 MSSA and 5 MRSA...... isolates belonging to CC30. The presence of quaternary ammonium compound (QAC) resistance efflux pumps was analyzed using an ethidium bromide accumulation assay. The presence of qac resistance genes in active efflux pump positive isolates was determined by whole-genome sequencing data. All isolates were...

  10. Modeling and simulation of syngas purification and power generation in integrated gasification combined cycle (IGCS)

    Energy Technology Data Exchange (ETDEWEB)

    Mehmood, N; Zaman, Z U; Mehran, M T [National Development, Islamabad (Pakistan)

    2011-07-01

    Integrated Gasification Combined Cycle (IGCC) is one of the most promising technologies for power generation; The environmental benefits and the higher energy conversion efficiency distinguish it from traditional coal generation technologies. This work presents a structured and validated conceptual model of purification of coal gas produced during the Underground Coal Gasification (UCG) of coal containing high sulfur contents. Gas cleaning operations for CO/sub 2/, H/sub 2/S and moisture removal have been modeled in steady and dynamic state. The power generation from combined cycle is also modeled. The model has been developed using Aspen HYSYS and Aspen Plus simulation software. Predicted results of clean gas composition and generated power present a good agreement with industrial data and efficiency parameters. This study is aimed at obtaining optimal assessment of an integrated gasification combined cycle (IGCC) power plant configurations. (author)

  11. Modeling and simulation of syngas purification and power generation in integrated gasification combined cycle (IGCS)

    International Nuclear Information System (INIS)

    Mehmood, N.; Zaman, Z.U.; Mehran, M.T.

    2011-01-01

    Integrated Gasification Combined Cycle (IGCC) is one of the most promising technologies for power generation; The environmental benefits and the higher energy conversion efficiency distinguish it from traditional coal generation technologies. This work presents a structured and validated conceptual model of purification of coal gas produced during the Underground Coal Gasification (UCG) of coal containing high sulfur contents. Gas cleaning operations for CO/sub 2/, H/sub 2/S and moisture removal have been modeled in steady and dynamic state. The power generation from combined cycle is also modeled. The model has been developed using Aspen HYSYS and Aspen Plus simulation software. Predicted results of clean gas composition and generated power present a good agreement with industrial data and efficiency parameters. This study is aimed at obtaining optimal assessment of an integrated gasification combined cycle (IGCC) power plant configurations. (author)

  12. Economic comparison of clean coal generating technologies with natural gas-combined cycle systems

    International Nuclear Information System (INIS)

    Sebesta, J.J.; Hoskins, W.W.

    1990-01-01

    This paper reports that there are four combustion technologies upon which U.S. electric utilities are expected to rely for the majority of their future power generating needs. These technologies are pulverized coal- fired combustion (PC); coal-fired fluidized bed combustion (AFBC); coal gasification, combined cycle systems (CGCC); and natural gas-fired combined cycle systems (NGCC). The engineering and economic parameters which affect the choice of a technology include capital costs, operating and maintenance costs, fuel costs, construction schedule, process risk, environmental and site impacts, fuel efficiency and flexibility, plant availability, capacity factors, timing of startup, and the importance of utility economic and financial factors

  13. Selective degradation of the recalcitrant cell wall of Scenedesmus quadricauda CASA CC202.

    Science.gov (United States)

    Reshma, Ragini; Arumugam, Muthu

    2017-10-01

    An eco-friendly cell wall digestion strategy was developed to enhance the availability of nutritionally important bio molecules of edible microalgae and exploit them for cloning, transformation, and expression of therapeutic proteins. Microalgae are the source for many nutritionally important bioactive compounds and potential drugs. Even though edible microalgae are rich in nutraceutical, bioavailability of all these molecules is very less due to their rigid recalcitrant cell wall. For example, the cell wall of Scenedesmus quadricauda CASA CC202 is made up of three layers comprising of rigid outer pectin and inner cellulosic layer separated by a thin middle layer. In the present investigation, a comprehensive method has been developed for the selective degradation of S. quadricauda CASA CC202 cell wall, by employing both mechanical and enzymatic treatments. The efficiency of cell wall removal was evaluated by measuring total reducing sugar (TRS), tannic acid-ferric chloride staining, calcoflour white staining, scanning electron microscopy (SEM), and Fourier transform infrared spectroscopy (FTIR) analysis. It was confirmed that the yield of TRS increased from 129.82 mg/g in 14 h from pectinase treatment alone to 352.44 mg/g by combined sonication and enzymatic treatment within 12 h. As a result, the combination method was found to be effective for the selective degradation of S. quadricauda CASA CC202 cell wall. This study will form a base for our future works, where this will help to enhance the digestibility and availability of nutraceutically important proteins.

  14. Estimating the power efficiency of the thermal power plant modernization by using combined-cycle technologies

    International Nuclear Information System (INIS)

    Hovhannisyan, L.S.; Harutyunyan, N.R.

    2013-01-01

    The power efficiency of the thermal power plant (TPP) modernization by using combined-cycle technologies is introduced. It is shown that it is possible to achieve the greatest decrease in the specific fuel consumption at modernizing the TPP at the expense of introducing progressive 'know-how' of the electric power generation: for TPP on gas, it is combined-cycle, gas-turbine superstructures of steam-power plants and gas-turbines with heat utilization

  15. Multi-objective thermodynamic optimization of combined Brayton and inverse Brayton cycles using genetic algorithms

    International Nuclear Information System (INIS)

    Besarati, S.M.; Atashkari, K.; Jamali, A.; Hajiloo, A.; Nariman-zadeh, N.

    2010-01-01

    This paper presents a simultaneous optimization study of two outputs performance of a previously proposed combined Brayton and inverse Brayton cycles. It has been carried out by varying the upper cycle pressure ratio, the expansion pressure of the bottom cycle and using variable, above atmospheric, bottom cycle inlet pressure. Multi-objective genetic algorithms are used for Pareto approach optimization of the cycle outputs. The two important conflicting thermodynamic objectives that have been considered in this work are net specific work (w s ) and thermal efficiency (η th ). It is shown that some interesting features among optimal objective functions and decision variables involved in the Baryton and inverse Brayton cycles can be discovered consequently.

  16. Study on economic potential of nuclear-gas combined cycle power generation in Chinese market

    International Nuclear Information System (INIS)

    Zhou Zhiwei; Bian Zhiqiang; Yang Mengjia

    2004-01-01

    Facing the challenges of separation of electric power plant and grid, and the deregulation of Chinese electricity supplying market in near future, nuclear power plants mainly operated as based load at the present regulated market should look for new operation mode. The economics of electric generation with nuclear-natural gas combined cycle is studied based on current conditions of natural gas and nuclear power plants in China. The results indicate that the technology development of nuclear-natural gas combined cycle for power generation is of potential prospects in Chinese electric market. (authors)

  17. The development and chemistry of high efficiency combined cycle plants

    International Nuclear Information System (INIS)

    Svoboda, Robert

    1999-01-01

    This paper presents a boiler concept based on the combination of a low-pressure drum-type boiler with high-pressure once-through boiler and the appropriate water/steam cycle. An all volatile treatment is used in the low-pressure boiler and oxygenated treatment for the once-through high pressure system. Impurity control is achieved by adapted system design and materials, high quality make-up, an appropriate cleanliness concept and clean-up procedures for a cold start. Cycle refreshing is realized by blowdown from the high-pressure water-separator. This concept utilizes simper and less equipment than traditional solutions, resulting in increased power plant reliability and less requirement on maintenance and on capital cost [it

  18. A Combined High and Low Cycle Fatigue Model for Life Prediction of Turbine Blades

    Directory of Open Access Journals (Sweden)

    Shun-Peng Zhu

    2017-06-01

    Full Text Available Combined high and low cycle fatigue (CCF generally induces the failure of aircraft gas turbine attachments. Based on the aero-engine load spectrum, accurate assessment of fatigue damage due to the interaction of high cycle fatigue (HCF resulting from high frequency vibrations and low cycle fatigue (LCF from ground-air-ground engine cycles is of critical importance for ensuring structural integrity of engine components, like turbine blades. In this paper, the influence of combined damage accumulation on the expected CCF life are investigated for turbine blades. The CCF behavior of a turbine blade is usually studied by testing with four load-controlled parameters, including high cycle stress amplitude and frequency, and low cycle stress amplitude and frequency. According to this, a new damage accumulation model is proposed based on Miner’s rule to consider the coupled damage due to HCF-LCF interaction by introducing the four load parameters. Five experimental datasets of turbine blade alloys and turbine blades were introduced for model validation and comparison between the proposed Miner, Manson-Halford, and Trufyakov-Kovalchuk models. Results show that the proposed model provides more accurate predictions than others with lower mean and standard deviation values of model prediction errors.

  19. Combined Turbine and Cycle Optimization for Organic Rankine Cycle Power Systems—Part B: Application on a Case Study

    Directory of Open Access Journals (Sweden)

    Angelo La Seta

    2016-05-01

    Full Text Available Organic Rankine cycle (ORC power systems have recently emerged as promising solutions for waste heat recovery in low- and medium-size power plants. Their performance and economic feasibility strongly depend on the expander. The design process and efficiency estimation are particularly challenging due to the peculiar physical properties of the working fluid and the gas-dynamic phenomena occurring in the machine. Unlike steam Rankine and Brayton engines, organic Rankine cycle expanders combine small enthalpy drops with large expansion ratios. These features yield turbine designs with few highly-loaded stages in supersonic flow regimes. Part A of this two-part paper has presented the implementation and validation of the simulation tool TURAX, which provides the optimal preliminary design of single-stage axial-flow turbines. The authors have also presented a sensitivity analysis on the decision variables affecting the turbine design. Part B of this two-part paper presents the first application of a design method where the thermodynamic cycle optimization is combined with calculations of the maximum expander performance using the mean-line design tool described in part A. The high computational cost of the turbine optimization is tackled by building a model which gives the optimal preliminary design of an axial-flow turbine as a function of the cycle conditions. This allows for estimating the optimal expander performance for each operating condition of interest. The test case is the preliminary design of an organic Rankine cycle turbogenerator to increase the overall energy efficiency of an offshore platform. For an increase in expander pressure ratio from 10 to 35, the results indicate up to 10% point reduction in expander performance. This corresponds to a relative reduction in net power output of 8.3% compared to the case when the turbine efficiency is assumed to be 80%. This work also demonstrates that this approach can support the plant designer

  20. Economic optimization of the combined cycle integrated with multi-product gasification system

    International Nuclear Information System (INIS)

    Liszka, M.; Ziebik, A.

    2009-01-01

    The system taken into consideration consists of the Corex unit, combined cycle power plant and air separation unit (ASU). The Corex process (trademark of Siemens-VAI) is one of technologies for cokeless hot metal production. Coal is gasified by oxygen in the hot metal environment. The excess gas can be used out of installation. It has been assumed that the Corex export gas is fired in combined cycle. The gas turbine (GT) structure was assumed as a fixed simple cycle while the heat recovery steam generator (HRSG) and steam turbine arrangements are free for optimization. The examples of independent variables selected for optimization are number of HRSG pressure levels, GT pressure ratio, minimal temperature differences in HRSG, flow rate of compressed air form GT compressor to ASU. Finally, 16 independent variables have been qualified for optimization. The synthesis optimization is based on the superstructure method. The economic net present value (NPV) has been chosen as the objective function. All power plant facilities have been modeled on the GateCycle software. The off-design models include, among others, the GT blade cooling and HRSG heat transfer coefficient analyses. Two optimization methods - genetic algorithm and Powells conjugate directions have been coupled in one hybrid procedure. The whole optimization analysis has been repeated several times for different price scenarios on the coal, iron and electricity markets

  1. Research Technology (ASTP) Rocket Based Combined Cycle (RBCC) Engine

    Science.gov (United States)

    2004-01-01

    Pictured is an artist's concept of the Rocket Based Combined Cycle (RBCC) launch. The RBCC's overall objective is to provide a technology test bed to investigate critical technologies associated with opperational usage of these engines. The program will focus on near term technologies that can be leveraged to ultimately serve as the near term basis for Two Stage to Orbit (TSTO) air breathing propulsions systems and ultimately a Single Stage To Orbit (SSTO) air breathing propulsion system.

  2. Optimization of fog inlet air cooling system for combined cycle power plants using genetic algorithm

    International Nuclear Information System (INIS)

    Ehyaei, Mehdi A.; Tahani, Mojtaba; Ahmadi, Pouria; Esfandiari, Mohammad

    2015-01-01

    In this research paper, a comprehensive thermodynamic modeling of a combined cycle power plant is first conducted and the effects of gas turbine inlet fogging system on the first and second law efficiencies and net power outputs of combined cycle power plants are investigated. The combined cycle power plant (CCPP) considered for this study consist of a double pressure heat recovery steam generator (HRSG) to utilize the energy of exhaust leaving the gas turbine and produce superheated steam to generate electricity in the Rankine cycle. In order to enhance understanding of this research and come up with optimum performance assessment of the plant, a complete optimization is using a genetic algorithm conducted. In order to achieve this goal, a new objective function is defined for the system optimization including social cost of air pollution for the power generation systems. The objective function is based on the first law efficiency, energy cost and the external social cost of air pollution for an operational system. It is concluded that using inlet air cooling system for the CCPP system and its optimization results in an increase in the average output power, first and second law efficiencies by 17.24%, 3.6% and 3.5%, respectively, for three warm months of year. - Highlights: • To model the combined cycle power plant equipped with fog inlet air cooling method. • To conduct both exergy and economic analyses for better understanding. • To conduct a complete optimization using a genetic algorithm to determine the optimal design parameters of the system

  3. Technical and economic assessment of the integrated solar combined cycle power plants in Iran

    International Nuclear Information System (INIS)

    Soltani Hosseini, M.; Hosseini, R.; Valizadeh, G.H.

    2002-01-01

    Thermal efficiency, capacity factor, environmental considerations, investment cost, fuel and O and M costs are the main parameters for technical and economic assessment of solar power plants. This analysis has shown that the Integrated Solar Combined Cycle System with 67 MW e solar field(ISCCS-67) is the most suitable plan for the first solar power plant in Iran. The Levelized Energy Costs of combined cycle and ISCCS-67 power plants would be equal if 49 million dollars of ISCCS-67 capital cost supplied by the international environmental organizations such as Global Environmental Facilities and World Bank. This study shows that an ISCCS-67 saves 59 million dollars in fuel consumption and reduces about 2.4 million ton in CO 2 emission during 30 years operating period. Increasing of steam turbine capacity by 50%, and 4% improvement in overall efficiency are other advantages of iSCCS-67 power plant. The LEC of ISCCS-67 is 10% and so 33% lower than the combined cycle and gas turbine, respectively, at the same capacity factor with consideration of environmental costs

  4. [Comporison Sduty of Microstructure by Metallographicalk on the Polarized Light and Texture by XRD of CC 5083 and CC 5182 Aluminium Alloy after Cold Rolling and Recrystallization].

    Science.gov (United States)

    Chen, Ming-biao; Li, Yong-wei; Tan, Yuan-biao; Ma, Min; Wang, Xue-min; Liu, Wen-chang

    2015-03-01

    At present the study of relation between microstructure, texture and performance of CC 5083 aluminium alloy after cold tolling and recrystallization processes is still finitude. So that the use of the CC 5083 aluminium alloy be influenced. Be cased into electrical furnace, hot up with unlimited speed followed the furnace hot up to different temperature and annealed 2h respectively, and be cased into salt-beth furnace, hot up quickly to different temperature and annealed 30 min respectively for CC 5083 and CC 5182 aluminum alloy after cold roling with 91.5% reduction. The microstructure be watched use metallographic microscope, the texture be inspected by XRD. The start temperature of recrystallization and grain grow up temperature within annealing in the electric furnace of CC 5083 aluminum alloy board is 343 degrees C, and the shap of grain after grow up with long strip (the innovation point ); The start temperature of recrystallization within annealling in the salt bath furnace of CC 5083 is 343 degrees C. The start temperature and end temperature of recrystallization within annealling of CC 5083 and CC 5182 aluminum alloy is 371 degrees C. The grain grow up outstanding of cold rooled CC 5152 aluminum alloy after annealed with 454 degrees C in the electric furnace and salt bath furnace. The start temperature of grain grow up of CC 5083 alluminurn alloy annealed in the electric furnace and salt bath furnace respectively is higher than the start temperature of grain grow up of CC 5182 alluminum alloy annealed in the electric furnace and salt bath furnace respectively. The strat temperature of recrystallization grain grow up is higher than which annealled with other three manner annealing process. The recrystallization temperature of CC 5182 annealed in the salt bath furnace is higher than which annealed in the electric furnace. The recrystallization temperature of the surface layer of CC 5083 and CC 5182 aluminum alloy is higher than the inner layer (the innovation

  5. Integrated gasification combined cycle for acid rain control

    Energy Technology Data Exchange (ETDEWEB)

    Simbeck, D.R.; Dickenson, R.L.

    1986-10-01

    The role of integrated coal gasification combined-cycle power plants in the abatement of emission of SO/sub 2/ and NO/sub 2/ which lead to acid rain is discussed. The economics of this IGCC approach are assessed for a nominal 500 MW plant size. Phased construction of IGCC plants is recommended as a means of reducing SO/sub 2/ and NO/sub x/ emissions noting that high-sulfur coals could continue to be used. It is also noted that phased construction IGCC is the only acid rain control technology that greatly reduces NO/sub x/. 17 references.

  6. Integrated operation and management system for a 700MW combined cycle power plant

    Energy Technology Data Exchange (ETDEWEB)

    Shiroumaru, I. (Yanai Power Plant Construction Office, Chugoku Electric Power Co., Inc., 1575-5 Yanai-Miyamoto-Shiohama, Yanai-shi, Yamaguchi-ken (JP)); Iwamiya, T. (Omika Works, Hitachi, Ltd., 5-2-1 Omika-cho, Hitachi-shi, Ibaraki-ken (JP)); Fukai, M. (Hitachi Works, Hitachi, Ltd., 3-1-1 Saiwai-cho, Hitachi-shi, Ibaraki-ken (JP))

    1992-03-01

    Yanai Power Plant of the Chugoku Electric Power Co., Inc. (Yamaguchi Pref., Japan) is in the process of constructing a 1400MW state-of-the-art combined cycle power plant. The first phase, a 350MW power plant, started operation on a commercial basis in November, 1990. This power plant has achieved high efficiency and high operability, major features of a combined cycle power plant. The integrated operation and management system of the power plant takes care of operation, maintenance, control of general business, etc., and was built using the latest computer and digital control and communication technologies. This paper reports that it is expected that this system will enhance efficient operation and management for the power plant.

  7. Off-design performance of a chemical looping combustion (CLC) combined cycle: effects of ambient temperature

    Science.gov (United States)

    Chi, Jinling; Wang, Bo; Zhang, Shijie; Xiao, Yunhan

    2010-02-01

    The present work investigates the influence of ambient temperature on the steady-state off-design thermodynamic performance of a chemical looping combustion (CLC) combined cycle. A sensitivity analysis of the CLC reactor system was conducted, which shows that the parameters that influence the temperatures of the CLC reactors most are the flow rate and temperature of air entering the air reactor. For the ambient temperature variation, three off-design control strategies have been assumed and compared: 1) without any Inlet Guide Vane (IGV) control, 2) IGV control to maintain air reactor temperature and 3) IGV control to maintain constant fuel reactor temperature, aside from fuel flow rate adjusting. Results indicate that, compared with the conventional combined cycle, due to the requirement of pressure balance at outlet of the two CLC reactors, CLC combined cycle shows completely different off-design thermodynamic characteristics regardless of the control strategy adopted. For the first control strategy, temperatures of the two CLC reactors both rise obviously as ambient temperature increases. IGV control adopted by the second and the third strategy has the effect to maintain one of the two reactors' temperatures at design condition when ambient temperature is above design point. Compare with the second strategy, the third would induce more severe decrease of efficiency and output power of the CLC combined cycle.

  8. Life cycle assessment of a biomass gasification combined-cycle power system

    Energy Technology Data Exchange (ETDEWEB)

    Mann, M.K.; Spath, P.L.

    1997-12-01

    The potential environmental benefits from biomass power are numerous. However, biomass power may also have some negative effects on the environment. Although the environmental benefits and drawbacks of biomass power have been debated for some time, the total significance has not been assessed. This study serves to answer some of the questions most often raised in regard to biomass power: What are the net CO{sub 2} emissions? What is the energy balance of the integrated system? Which substances are emitted at the highest rates? What parts of the system are responsible for these emissions? To provide answers to these questions, a life cycle assessment (LCA) of a hypothetical biomass power plant located in the Midwest United States was performed. LCA is an analytical tool for quantifying the emissions, resource consumption, and energy use, collectively known as environmental stressors, that are associated with converting a raw material to a final product. Performed in conjunction with a technoeconomic feasibility study, the total economic and environmental benefits and drawbacks of a process can be quantified. This study complements a technoeconomic analysis of the same process, reported in Craig and Mann (1996) and updated here. The process studied is based on the concept of power Generation in a biomass integrated gasification combined cycle (BIGCC) plant. Broadly speaking, the overall system consists of biomass production, its transportation to the power plant, electricity generation, and any upstream processes required for system operation. The biomass is assumed to be supplied to the plant as wood chips from a biomass plantation, which would produce energy crops in a manner similar to the way food and fiber crops are produced today. Transportation of the biomass and other materials is by both rail and truck. The IGCC plant is sized at 113 MW, and integrates an indirectly-heated gasifier with an industrial gas turbine and steam cycle. 63 refs., 34 figs., 32 tabs.

  9. Life cycle assessment of a biomass gasification combined-cycle power system

    Energy Technology Data Exchange (ETDEWEB)

    Mann, M.K.; Spath, P.L.

    1997-12-01

    The potential environmental benefits from biomass power are numerous. However, biomass power may also have some negative effects on the environment. Although the environmental benefits and drawbacks of biomass power have been debated for some time, the total significance has not been assessed. This study serves to answer some of the questions most often raised in regard to biomass power: What are the net CO{sub 2} emissions? What is the energy balance of the integrated system? Which substances are emitted at the highest rates? What parts of the system are responsible for these emissions? To provide answers to these questions, a life cycle assessment (LCA) of a hypothetical biomass power plant located in the Midwest United States was performed. LCA is an analytical tool for quantifying the emissions, resource consumption, and energy use, collectively known as environmental stressors, that are associated with converting a raw material to a final product. Performed in conjunction with a t echnoeconomic feasibility study, the total economic and environmental benefits and drawbacks of a process can be quantified. This study complements a technoeconomic analysis of the same process, reported in Craig and Mann (1996) and updated here. The process studied is based on the concept of power Generation in a biomass integrated gasification combined cycle (BIGCC) plant. Broadly speaking, the overall system consists of biomass production, its transportation to the power plant, electricity generation, and any upstream processes required for system operation. The biomass is assumed to be supplied to the plant as wood chips from a biomass plantation, which would produce energy crops in a manner similar to the way food and fiber crops are produced today. Transportation of the biomass and other materials is by both rail and truck. The IGCC plant is sized at 113 MW, and integrates an indirectly-heated gasifier with an industrial gas turbine and steam cycle. 63 refs., 34 figs., 32 tabs.

  10. HfC plasma coating of C/C composites

    International Nuclear Information System (INIS)

    Boncoeur, M.; Schnedecker, G.; Lulewicz, J.D.

    1992-01-01

    The surface properties of C/C composites such as hardness and corrosion or erosion resistance can be modified by a ceramic coating applied by plasma torch. The technique of plasma spraying in controlled temperature and atmosphere, that was developed and patented by the CEA, makes it possible to apply coatings to the majority of metals and ceramics without affecting the characteristics of the composite. An example of hard deposit of HfC on a C/C composite is described. The characteristics of the deposit and of the bonding with the C/C composite were studied before and after a heat treatment under vacuum for 2 hours at 1000 C. 2 refs

  11. Combined Heat and Power: Coal-Fired Air Turbine (CAT)-Cycle Plant

    International Nuclear Information System (INIS)

    Lee Recca

    1999-01-01

    By combining an integrated system with a gas turbine, coal-fired air turbine cycle technology can produce energy at an efficiency rate of over 40%, with capital and operating costs below those of competing conventional systems. Read this fact sheet to discover the additional benefits of this exciting new technology

  12. Environmental Assessment for the Warren Station externally fired combined cycle demonstration project

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-04-01

    The proposed Penelec project is one of 5 projects for potential funding under the fifth solicitation under the Clean Coal Technology program. In Penelec, two existing boilers would be replaced at Warren Station, PA; the new unit would produce 73 MW(e) in a combined cycle mode (using both gas-fired and steam turbines). The project would fill the need for a full utility-size demonstration of externally fire combined cycle (EFCC) technology as the next step toward commercialization. This environmental assessment was prepared for compliance with NEPA; its purpose is to provide sufficient basis for determining whether to prepare an environmental impact statement or to issue a finding of no significant impact. It is divided into the sections: purpose and need for proposed action; alternatives; brief description of affected environment; environmental consequences, including discussion of commercial operation beyond the demonstration period.

  13. Biomass Gasification Combined Cycle

    Energy Technology Data Exchange (ETDEWEB)

    Judith A. Kieffer

    2000-07-01

    Gasification combined cycle continues to represent an important defining technology area for the forest products industry. The ''Forest Products Gasification Initiative'', organized under the Industry's Agenda 2020 technology vision and supported by the DOE ''Industries of the Future'' program, is well positioned to guide these technologies to commercial success within a five-to ten-year timeframe given supportive federal budgets and public policy. Commercial success will result in significant environmental and renewable energy goals that are shared by the Industry and the Nation. The Battelle/FERCO LIVG technology, which is the technology of choice for the application reported here, remains of high interest due to characteristics that make it well suited for integration with the infrastructure of a pulp production facility. The capital cost, operating economics and long-term demonstration of this technology area key input to future economically sustainable projects and must be verified by the 200 BDT/day demonstration facility currently operating in Burlington, Vermont. The New Bern application that was the initial objective of this project is not currently economically viable and will not be implemented at this time due to several changes at and around the mill which have occurred since the inception of the project in 1995. The analysis shows that for this technology, and likely other gasification technologies as well, the first few installations will require unique circumstances, or supportive public policies, or both to attract host sites and investors.

  14. Gas-steam combined cycles for power generation: Current state-of-the-art and future prospects

    International Nuclear Information System (INIS)

    Macchi, E.; Chiesa, P.; Consonni, S.; Lozza, G.

    1992-01-01

    The first part of this paper points out the many factors which, after years of stagnation in the electric power industry, are giving rise to a true revolution in power generation engineering: the passing from closed cycles, using steam as the working fluid and energy sources external to the power cycle, to the use of open cycles, in which the primary energy source, in the form of a fuel, is directly immersed in the working fluid of the engine. Attention is given to the advantages in terms of energy and cost savings, greater flexibility in energy policy options and pollution abatement which are now being afforded through the use of gas turbines with combined gas-steam cycles. The second part of the paper deals with an assessment of the current state-of-the-art of the technology relative to these innovative power systems. The assessment is followed by a review of foreseen developments in combined cycle system design, choice of construction materials, type of cooling systems, operating temperatures and performance capabilities

  15. Measurements of psi -> K-Lambda(Xi)over-bar(+) + c.c. and psi -> gamma K-Lambda(Xi)over-bar(+) + c.c.

    NARCIS (Netherlands)

    Ablikim, M.; Achasov, M. N.; Ai, X. C.; Albayrak, O.; Albrecht, M.; Ambrose, D. J.; Amoroso, A.; An, F. F.; An, Q.; Bai, J. Z.; Ferroli, R. Baldini; Ban, Y.; Bennett, D. W.; Bennett, J. V.; Bertani, M.; Bettoni, D.; Bian, J. M.; Bianchi, F.; Boger, E.; Bondarenko, O.; Boyko, I.; Briere, R. A.; Cai, H.; Cai, X.; Cakir, O.; Calcaterra, A.; Cao, G. F.; Cetin, S. A.; Chang, J. F.; Chelkov, G.; Chen, G.; Chen, H. S.; Chen, H. Y.; Chen, J. C.; Chen, M. L.; Chen, S. J.; Chen, X.; Chen, X. R.; Chen, Y. B.; Cheng, H. P.; Chu, X. K.; Cibinetto, G.; Cronin-Hennessy, D.; Dai, H. L.; Dai, J. P.; Dbeyssi, A.; Dedovich, D.; Deng, Z. Y.; Denig, A.; Denysenko, I.; Destefanis, M.; De Mori, F.; Ding, Y.; Dong, C.; Dong, J.; Dong, L. Y.; Dong, M. Y.; Duan, S. X.; Duan, P. F.; Fan, J. Z.; Fang, J.; Fang, S. S.; Fang, X.; Fang, Y.; Fava, L.; Feldbauer, F.; Felici, G.; Feng, C. Q.; Fioravanti, E.; Fritsch, M.; Fu, C. D.; Gao, Q.; Gao, X. Y.; Gao, Y.; Gao, Z.; Garzia, I.; Geng, C.; Goetzen, K.; Gong, W. X.; Gradl, W.; Greco, M.; Gu, M. H.; Gu, Y. T.; Guan, Y. H.; Guo, A. Q.; Guo, L. B.; Guo, Y.; Guo, Y. P.; Haddadi, Z.; Hafner, A.; Han, S.; Han, Y. L.; Hao, X. Q.; Harris, F. A.; He, K. L.; He, Z. Y.; Held, T.; Heng, Y. K.; Hou, Z. L.; Hu, C.; Hu, H. M.; Hu, J. F.; Hu, T.; Hu, Y.; Huang, G. M.; Huang, G. S.; Huang, H. P.; Huang, J. S.; Huang, X. T.; Huang, Y.; Hussain, T.; Ji, Q.; Ji, Q. P.; Ji, X. B.; Ji, X. L.; Jiang, L. L.; Jiang, L. W.; Jiang, X. S.; Jiao, J. B.; Jiao, Z.; Jin, D. P.; Jin, S.; Johansson, T.; Julin, A.; Kalantar-Nayestanaki, N.; Kang, X. L.; Kang, X. S.; Kavatsyuk, M.; Ke, B. C.; Kliemt, R.; Kloss, B.; Kolcu, O. B.; Kopf, B.; Kornicer, M.; Kuehn, W.; Kupsc, A.; Lai, W.; Lange, J. S.; Lara, M.; Larin, P.; Leng, C.; Li, C. H.; Li, Cheng; Li, D. M.; Li, F.; Li, G.; Li, H. B.; Li, J. C.; Li, Jin; Li, K.; Li, K.; Li, Lei; Li, P. R.; Li, T.; Li, W. D.; Li, W. G.; Li, X. L.; Li, X. M.; Li, X. N.; Li, X. Q.; Li, Z. B.; Liang, H.; Liang, Y. F.; Liang, Y. T.; Liao, G. R.; Lin, D. X.; Liu, B. J.; Liu, C. X.; Liu, F. H.; Liu, Fang; Liu, Feng; Liu, H. B.; Liu, H. H.; Liu, H. H.; Liu, H. M.; Liu, J.; Liu, J. P.; Liu, J. Y.; Liu, K.; Liu, K. Y.; Liu, L. D.; Liu, P. L.; Liu, Q.; Liu, S. B.; Liu, X.; Liu, X. X.; Liu, Y. B.; Liu, Z. A.; Liu, Zhiqiang; Liu, Zhiqing; Loehner, H.; Lou, X. C.; Lu, H. J.; Lu, J. G.; Lu, R. Q.; Lu, Y.; Lu, Y. P.; Luo, C. L.; Luo, M. X.; Luo, T.; Luo, X. L.; Lv, M.; Lyu, X. R.; Ma, F. C.; Ma, H. L.; Ma, L. L.; Ma, Q. M.; Ma, S.; Ma, T.; Ma, X. N.; Ma, X. Y.; Maas, F. E.; Maggiora, M.; Malik, Q. A.; Mao, Y. J.; Mao, Z. P.; Marcello, S.; Messchendorp, J. G.; Min, J.; Min, T. J.; Mitchell, R. E.; Mo, X. H.; Mo, Y. J.; Morales, C. Morales; Moriya, K.; Muchnoi, N. Yu.; Muramatsu, H.; Nefedov, Y.; Nerling, F.; Nikolaev, I. B.; Ning, Z.; Nisar, S.; Niu, S. L.; Niu, X. Y.; Olsen, S. L.; Ouyang, Q.; Pacetti, S.; Patteri, P.; Pelizaeus, M.; Peng, H. P.; Peters, K.; Pettersson, J.; Ping, J. L.; Ping, R. G.; Poling, R.; Pu, Y. N.; Qi, M.; Qian, S.; Qiao, C. F.; Qin, L. Q.; Qin, N.; Qin, X. S.; Qin, Y.; Qin, Z. H.; Qiu, J. F.; Rashid, K. H.; Redmer, C. F.; Ren, H. L.; Ripka, M.; Rong, G.; Ruan, X. D.; Santoro, V.; Sarantsev, A.; Savrie, M.; Schoenning, K.; Schumann, S.; Shan, W.; Shao, M.; Shen, C. P.; Shen, P. X.; Shen, X. Y.; Sheng, H. Y.; Song, W. M.; Song, X. Y.; Sosio, S.; Spataro, S.; Sun, G. X.; Sun, J. F.; Sun, S. S.; Sun, Y. J.; Sun, Y. Z.; Sun, Z. J.; Sun, Z. T.; Tang, C. J.; Tang, X.; Tapan, I.; Thorndike, E. H.; Tiemens, M.; Toth, D.; Ullrich, M.; Uman, I.; Varner, G. S.; Wang, B.; Wang, B. L.; Wang, D.; Wang, D. Y.; Wang, K.; Wang, L. L.; Wang, L. S.; Wang, M.; Wang, P.; Wang, P. L.; Wang, Q. J.; Wang, S. G.; Wang, W.; Wang, X. F.; Wang, Y. D.; Wang, Y. F.; Wang, Y. Q.; Wang, Z.; Wang, Z. G.; Wang, Z. H.; Wang, Z. Y.; Weber, T.; Wei, D. H.; Wei, J. B.; Weidenkaff, P.; Wen, S. P.; Wiedner, U.; Wolke, M.; Wu, L. H.; Wu, Z.; Xia, L. G.; Xia, Y.; Xiao, D.; Xiao, Z. J.; Xie, Y. G.; Xiu, Q. L.; Xu, G. F.; Xu, L.; Xu, Q. J.; Xu, Q. N.; Xu, X. P.; Yan, L.; Yan, W. B.; Yan, W. C.; Yan, Y. H.; Yang, H. X.; Yang, L.; Yang, Y.; Yang, Y. X.; Ye, H.; Ye, M.; Ye, M. H.; Yin, J. H.; Yu, B. X.; Yu, C. X.; Yu, H. W.; Yu, J. S.; Yuan, C. Z.; Yuan, W. L.; Yuan, Y.; Yuncu, A.; Zafar, A. A.; Zallo, A.; Zeng, Y.; Zhang, B. X.; Zhang, B. Y.; Zhang, C.; Zhang, C. C.; Zhang, D. H.; Zhang, H. H.; Zhang, H. Y.; Zhang, J. J.; Zhang, J. L.; Zhang, J. Q.; Zhang, J. W.; Zhang, J. Y.; Zhang, J. Z.; Zhang, K.; Zhang, L.; Zhang, S. H.; Zhang, X. Y.; Zhang, Y.; Zhang, Y. H.; Zhang, Y. T.; Zhang, Z. H.; Zhang, Z. P.; Zhang, Z. Y.; Zhao, G.; Zhao, H. S.; Zhao, J. W.; Zhao, J. Y.; Zhao, J. Z.; Zhao, Lei; Zhao, Ling; Zhao, M. G.; Zhao, Q.; Zhao, Q. W.; Zhao, S. J.; Zhao, T. C.; Zhao, Y. B.; Zhao, Z. G.; Zhemchugov, A.; Zheng, B.; Zheng, J. P.; Zheng, W. J.; Zheng, Y. H.; Zhong, B.; Zhou, L.; Zhou, Li; Zhou, X.; Zhou, X. K.; Zhou, X. R.; Zhou, X. Y.; Zhu, K.; Zhu, K. J.; Zhu, S.; Zhu, X. L.; Zhu, Y. C.; Zhu, Y. S.; Zhu, Z. A.; Zhuang, J.; Zotti, L.; Zou, B. S.; Zou, J. H.

    2015-01-01

    Using a sample of 1.06 x 10(8) psi(3686) events produced in e(+)e(-) collisions at root s = 3.686 GeV and collected with the BESIII detector at the BEPCII collider, we present studies of the decays psi(3686) -> K-Lambda(Xi) over bar (+) + c.c. and psi(3686) -> gamma K-Lambda(Xi) over bar (+) + c.c.

  16. Effect of simultaneously started clomiphene citrate and gonadotropins in antagonist regimes, on cumulative live births, fresh-cycle live births and cost of stimulation in IVF cycles.

    Science.gov (United States)

    Satwik, Ruma; Kochhar, Mohinder

    2018-04-11

    The aim of the study was to compare simultaneously started clomiphene citrate (CC) and gonadotropins (Gn) with gonadotropins alone in conventional antagonist regimes with respect to fresh-cycle live births, cumulative live births and cost of ovarian stimulation per started cycle. This was a single-center prospective cohort study conducted over 1 year. Women undergoing autologous in vitro fertilization (IVF) treatment in antagonist protocols and who consented to participate in the study were divided into two cohorts. The CC cohort (n = 86) received 50 mg CC for 5 days and individualized Gn daily until the hCG trigger, both starting from day 2 and antagonist daily from day 8 of menstrual cycle. The Gn-only cohort (n = 349) received individualized Gn from day 2 and the antagonist from day 7 of menstrual cycle. IVF outcomes and cost of stimulation were compared between two cohorts across expected ovarian response categories. The CC cohort used a mean lower dose of Gn (1741.38 ± 604.46 vs 1980.54 ± 686.42; MD = -239.16; 95%CI = -348.03 to -189.24; P = 0.003) over fewer days (8.54 ± 1.86 vs 9.25 ± 1.97; MD =-0.71;95% CI = -1.17 to -0.25; P = 0.0026) to achieve similar retrieved oocytes, (9.19 ± 5.92 vs 9.36 ± 6.96; MD = -0.17; 95%CI -1.77 to + 1.43; P = 0.83), positive bhCG rates (40% vs 29.6%, MD = 10.4%; OR = 1.65, 95%CI = 0.95-2.86; P = 0.078) and live births in fresh cycles (32.31% vs 21.30%; MD = 11.01%; OR = 1.76; 95%CI = 0.97-3.19; P = 0.06) and cumulative live births per initiated cycle (30.23% vs 20.34%; MD = 9.89%; OR = 1.697; 95%CI = 0.99-2.88; P = 0.0501). The dose lowering achieved a 28-40% reduction in the cost of stimulation, which was most noticeable in the hyper-responder category for both hMG cycles, (Rs.11 602.3 ± 3365.9 vs 19615 ± 2677.1; MD = -8012.7; %age reduction: 40.8%; P = 0.0007) and recombinant FSH cycles (Rs. 22

  17. Evaluation of alternatives of exothermic methanization cycle for combined electricity and heat generation

    International Nuclear Information System (INIS)

    Balajka, J.; Princova, H.

    1987-01-01

    The possibilities are discussed of using the ADAM-EVA system for remote heat supply from nuclear heat sources to district heating systems. Attention is devoted to the use of the exothermal methanization process (ADAM station) for the combined power and heat production, this making use of the existing hot water power distribution network. The basic parameter for the evaluation of the over-all efficiency of the combined power and heat production is the maximum methanization cycle temperature which depends on the life of the methanization catalyst. Upon temperature drop below 550 degC, the conversion process can only be secured by means of two-stage methanization, which leads to a simplification of the cycle and a reduction in investment cost. At a temperature lower than 500 degC, combined power and heat production cannot be implemented. On the contrary, a considerable amount of electric power supplied from outside the system would be needed for compression work. (Z.M.)

  18. Using an optimal CC-PLSR-RBFNN model and NIR spectroscopy for the starch content determination in corn

    Science.gov (United States)

    Jiang, Hao; Lu, Jiangang

    2018-05-01

    Corn starch is an important material which has been traditionally used in the fields of food and chemical industry. In order to enhance the rapidness and reliability of the determination for starch content in corn, a methodology is proposed in this work, using an optimal CC-PLSR-RBFNN calibration model and near-infrared (NIR) spectroscopy. The proposed model was developed based on the optimal selection of crucial parameters and the combination of correlation coefficient method (CC), partial least squares regression (PLSR) and radial basis function neural network (RBFNN). To test the performance of the model, a standard NIR spectroscopy data set was introduced, containing spectral information and chemical reference measurements of 80 corn samples. For comparison, several other models based on the identical data set were also briefly discussed. In this process, the root mean square error of prediction (RMSEP) and coefficient of determination (Rp2) in the prediction set were used to make evaluations. As a result, the proposed model presented the best predictive performance with the smallest RMSEP (0.0497%) and the highest Rp2 (0.9968). Therefore, the proposed method combining NIR spectroscopy with the optimal CC-PLSR-RBFNN model can be helpful to determine starch content in corn.

  19. Modelling and exergoeconomic-environmental analysis of combined cycle power generation system using flameless burner for steam generation

    International Nuclear Information System (INIS)

    Hosseini, Seyed Ehsan; Barzegaravval, Hasan; Ganjehkaviri, Abdolsaeid; Wahid, Mazlan Abdul; Mohd Jaafar, M.N.

    2017-01-01

    Highlights: • Using flameless burner as a supplementary firing system after gas turbine is modeled. • Thermodynamic, economic and environmental analyses of this model are performed. • Efficiency of the plant increases about 6% and CO_2 emission decreases up to 5.63% in this design. • Available exergy for work production in both gas cycle and steam cycle increases in this model. - Abstract: To have an optimum condition for the performance of a combined cycle power generation, using supplementary firing system after gas turbine was investigated by various researchers. Since the temperature of turbine exhaust is higher than auto-ignition temperature of the fuel in optimum condition, using flameless burner is modelled in this paper. Flameless burner is installed between gas turbine cycle and Rankine cycle of a combined cycle power plant which one end is connected to the outlet of gas turbine (as primary combustion oxidizer) and the other end opened to the heat recovery steam generator. Then, the exergoeconomic-environmental analysis of the proposed model is evaluated. Results demonstrate that efficiency of the combined cycle power plant increases about 6% and CO_2 emission reduces up to 5.63% in this proposed model. It is found that the variation in the cost is less than 1% due to the fact that a cost constraint is implemented to be equal or lower than the design point cost. Moreover, exergy of flow gases increases in all points except in heat recovery steam generator. Hence, available exergy for work production in both gas cycle and steam cycle will increase in new model.

  20. CcMP-II, a new hemorrhagic metalloproteinase from Cerastes cerastes snake venom: purification, biochemical characterization and amino acid sequence analysis.

    Science.gov (United States)

    Boukhalfa-Abib, Hinda; Laraba-Djebari, Fatima

    2015-01-01

    Snake venom metalloproteinases (SVMPs) are the most abundant components in snake venoms. They are important in the induction of systemic alterations and local tissue damage after envenomation. CcMP-II, which is a metalloproteinase purified from Cerastes cerastes snake venom, was obtained by a combination of gel filtration, ion-exchange and affinity chromatographies. It was homogeneous on SDS-PAGE, with a molecular mass estimated to 35kDa and presents a pI of 5.6. CcMP-II has an N-terminal sequence of EDRHINLVSVADHRMXTKY, with high levels of homology with those of the members of class P-II of SVMPs, which comprises metalloproteinase and disintegrin-like domains together. This proteinase displayed a fibrinogenolytic and hemorrhagic activities. The proteolytic and hemorrhagic activities of CcMP-II were inhibited by EDTA and 1,10-phenanthroline. However, these activities were not affected by aprotinine and PMSF, suggesting that CcMP-II is a zinc-dependent hemorrhagic metalloproteinase with an α-fibrinogenase activity. The hemorrhagic metalloproteinase CcMP-II was also able to hydrolyze extracellular matrix components, such as type IV collagen and laminin. These results indicate that CcMP-II is implicated in the local and systemic bleeding, contributing thus in the toxicity of C. cerastes venom. Copyright © 2014 Elsevier Inc. All rights reserved.

  1. B cell receptor pathway in chronic lymphocytic leukemia: specific role of CC-292

    Directory of Open Access Journals (Sweden)

    Arnason JE

    2014-01-01

    Full Text Available Jon E Arnason,1 Jennifer R Brown21Beth Israel Deaconess Medical Center, 2CLL Center, Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USAAbstract: Chronic lymphocytic leukemia (CLL is the most common adult leukemia. The current treatment paradigm involves the use of chemoimmunotherapy, when patients develop an indication for therapy. With this strategy, a majority of patients will obtain a remission, though cure remains elusive. While treatable, the majority of CLL patients will die of complications of their disease. Recent advances in the understanding of the importance of the B cell receptor (BCR pathway in CLL have led to the development of a number of agents targeting this pathway. In this review, we discuss recent developments in the targeting of the BCR pathway, with a focus on CC-292. CC-292 covalently binds to Bruton's tyrosine kinase, a key mediator of BCR signaling, and has demonstrated preclinical and clinical activity in CLL, with acceptable tolerability. Based on the success of CC-292 and other inhibitors of the BCR pathway, these agents are being investigated in combination with standard therapy, with the hope that they will increase the depth and length of response, without significant toxicity.Keywords: Bruton's tyrosine kinase inhibitor, ibrutinib

  2. Environmental impact efficiency of natural gas combined cycle power plants: A combined life cycle assessment and dynamic data envelopment analysis approach.

    Science.gov (United States)

    Martín-Gamboa, Mario; Iribarren, Diego; Dufour, Javier

    2018-02-15

    The energy sector is still dominated by the use of fossil resources. In particular, natural gas represents the third most consumed resource, being a significant source of electricity in many countries. Since electricity production in natural gas combined cycle (NGCC) plants provides some benefits with respect to other non-renewable technologies, it is often seen as a transitional solution towards a future low‑carbon power generation system. However, given the environmental profile and operational variability of NGCC power plants, their eco-efficiency assessment is required. In this respect, this article uses a novel combined Life Cycle Assessment (LCA) and dynamic Data Envelopment Analysis (DEA) approach in order to estimate -over the period 2010-2015- the environmental impact efficiencies of 20 NGCC power plants located in Spain. A three-step LCA+DEA method is applied, which involves data acquisition, calculation of environmental impacts through LCA, and the novel estimation of environmental impact efficiency (overall- and term-efficiency scores) through dynamic DEA. Although only 1 out of 20 NGCC power plants is found to be environmentally efficient, all plants show a relatively good environmental performance with overall eco-efficiency scores above 60%. Regarding individual periods, 2011 was -on average- the year with the highest environmental impact efficiency (95%), accounting for 5 efficient NGCC plants. In this respect, a link between high number of operating hours and high environmental impact efficiency is observed. Finally, preliminary environmental benchmarks are presented as an additional outcome in order to further support decision-makers in the path towards eco-efficiency in NGCC power plants. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. Integration of energy-efficient empty fruit bunch drying with gasification/combined cycle systems

    International Nuclear Information System (INIS)

    Aziz, Muhammad; Prawisudha, Pandji; Prabowo, Bayu; Budiman, Bentang Arief

    2015-01-01

    Highlights: • Novel integrated drying, gasification and combined cycle for empty fruit bunch. • Application of enhanced process integration to achieve high total energy efficiency. • The technology covers exergy recovery and process integration. • High overall energy efficiency can be achieved (about 44% including drying). - Abstract: A high-energy-efficient process for empty fruit bunch drying with integration to gasification and combined cycle processes is proposed. The enhancement is due to greater exergy recovery and more efficient process integration. Basically, the energy/heat involved in a single process is recovered as much as possible, leading to minimization of exergy destruction. In addition, the unrecoverable energy/heat is utilized for other processes through process integration. During drying, a fluidized bed dryer with superheated steam is used as the main evaporator. Exergy recovery is performed through exergy elevation via compression and effective heat coupling in a dryer and heat exchangers. The dried empty fruit bunches are gasified in a fluidized bed gasifier using air as the fluidizing gas. Furthermore, the produced syngas is utilized as fuel in the combined cycle module. From process analysis, the proposed integrated processes can achieve a relatively high energy efficiency. Compared to a standalone drying process employing exergy recovery, the proposed integrated drying can reduce consumed energy by about 1/3. In addition, the overall integrated processes can reach a total power generation efficiency of about 44%

  4. Adobe Edge Animate CC for dummies

    CERN Document Server

    Rohde, Michael

    2013-01-01

    The easy way to build HTML5 mobile and web apps using Adobe's new Edge Animate CC Edge Animate CC is an approachable WYSIWYG alternative for leveraging the power of languages like HTML5, CSS3, and JavaScript to design and develop for the web and mobile devices, even if you have no programming experience. Written by Michael Rohde, the book calls on this seasoned web developer's wealth of experience using Edge Animate CC, and a companion website includes all code from the book to help you apply what you learn as you go. Features an easy-to-use interface, with a propert

  5. Effect of combined β-alanine and sodium bicarbonate supplementation on cycling performance.

    Science.gov (United States)

    Bellinger, Phillip M; Howe, Samuel T; Shing, Cecilia M; Fell, James W

    2012-08-01

    The purpose of this study was to investigate the effects of 28 d of β-alanine supplementation on 4-min cycling time trial performance and to determine whether there was an additive effect of combined β-alanine and sodium bicarbonate (NaHCO3) supplementation on high-intensity cycling performance. Fourteen highly trained cyclists (mean ± SD: age = 25.4 ± 7.2 yr, mass = 71.1 ± 7.1 kg, V˙O(2max) = 66.6 ± 5.7 mL·kg·min) supplemented for 28 d with β-alanine (65 mg·kg body mass each day) or placebo. A maximal 4-min bout of cycling was performed before supplementation (baseline) and twice after supplementation: after ingestion of NaHCO3 (300 mg·kg body mass) and ingestion of a placebo using a randomized crossover design with 2 d between trials. Blood pH and HCO3 concentration were determined before loading (postsupplementation trials) and at pretest and posttest. In the acute NaHCO3 loading trials, blood pH and HCO3 were elevated from before loading to pretest, and the magnitude of the change in HCO3 from pretest to posttest was significantly greater compared with the acute placebo loading trial (P < 0.001). Average power output in the 4-min cycling performance trial was increased in placebo + NaHCO3 (+3.1% ± 1.8%) and β-alanine + NaHCO3 (+3.3% ± 3.0%) compared with baseline (P < 0.05). β-alanine + placebo did not significantly improve average power output compared with baseline (+1.6% ± 1.7%, P = 0.20); however, magnitude-based inferences demonstrated that β-alanine + placebo was associated with a 37% likelihood of producing average power improvements. In trained cyclists, β-alanine supplementation did not significantly improve 4-min cycling performance; however, there may be a small meaningful improvement in performance. Acute NaHCO3 supplementation significantly improved 4-min cycling performance. There seemed to be a minimal additive effect of combined β-alanine and NaHCO3 supplementation.

  6. Chemical vapor deposition of SiC on C-C composites as plasma facing materials for fusion application

    International Nuclear Information System (INIS)

    Kim, W. J.; Lee, M. Y.; Park, J. Y.; Hong, G. W.; Kim, J. I.; Choi, D. J.

    2000-01-01

    Because of the low activation and excellent mechanical properties at elevated temperatures, carbon-fiber reinforced carbon(C-C) composites have received much attention for plasma facing materials for fusion reactor and high-temperature structural applications such as aircrafts and space vehicles. These proposed applications have been frustrated by the lack of resistance to hydrogen erosion and oxidation on exposure to ambient oxidizing conditions at high temperature. Although Silicon Carbide (SiC) has shown excellent properties as an effective erosion-and oxidation-protection coating, many cracks are developed during fabrication and thermal cycles in use due to the Coefficients of Thermal Expansion(CTE) mismatch between SiC and C-C composite. In this study, we adopted a pyrolitic carbon as an interlayer between SiC and C-C substrate in order to minimize the CTE mismatch. The oxidation-protection performance of this composite was investigated as well

  7. A pair natural orbital implementation of the coupled cluster model CC2 for excitation energies.

    Science.gov (United States)

    Helmich, Benjamin; Hättig, Christof

    2013-08-28

    We demonstrate how to extend the pair natural orbital (PNO) methodology for excited states, presented in a previous work for the perturbative doubles correction to configuration interaction singles (CIS(D)), to iterative coupled cluster methods such as the approximate singles and doubles model CC2. The original O(N(5)) scaling of the PNO construction is reduced by using orbital-specific virtuals (OSVs) as an intermediate step without spoiling the initial accuracy of the PNO method. Furthermore, a slower error convergence for charge-transfer states is analyzed and resolved by a numerical Laplace transformation during the PNO construction, so that an equally accurate treatment of local and charge-transfer excitations is achieved. With state-specific truncated PNO expansions, the eigenvalue problem is solved by combining the Davidson algorithm with deflation to project out roots that have already been determined and an automated refresh with a generation of new PNOs to achieve self-consistency of the PNO space. For a large test set, we found that truncation errors for PNO-CC2 excitation energies are only slightly larger than for PNO-CIS(D). The computational efficiency of PNO-CC2 is demonstrated for a large organic dye, where a reduction of the doubles space by a factor of more than 1000 is obtained compared to the canonical calculation. A compression of the doubles space by a factor 30 is achieved by a unified OSV space only. Moreover, calculations with the still preliminary PNO-CC2 implementation on a series of glycine oligomers revealed an early break even point with a canonical RI-CC2 implementation between 100 and 300 basis functions.

  8. Carbon exergy tax applied to biomass integrated gasification combined cycle in sugarcane industry

    International Nuclear Information System (INIS)

    Fonseca Filho, Valdi Freire da; Matelli, José Alexandre; Perrella Balestieri, José Antonio

    2016-01-01

    The development of technologies based on energy renewable sources is increasing worldwide in order to diversify the energy mix and satisfy the rigorous environmental legislation and international agreements to reduce pollutant emission. Considering specific characteristics of biofuels available in Brazil, studies regarding such technologies should be carried out aiming energy mix diversification. Several technologies for power generation from biomass have been presented in the technical literature, and plants with BIGCC (biomass integrated gasification combined cycle) emerge as a major technological innovation. By obtaining a fuel rich in hydrogen from solid biomass gasification, BIGCC presents higher overall process efficiency than direct burning of the solid fuel in conventional boilers. The objective of this paper is to develop a thermodynamic and chemical equilibrium model of a BIGCC configuration for sugarcane bagasse. The model embodies exergetic cost and CO_2 emission analyses through the method of CET (carbon exergy tax). An exergetic penalty comparison between the BIGCC technology (with and without CO_2 capture and sequestration), a natural gas combined cycle and the traditional steam cycle of sugarcane sector is then presented. It is verified that the BIGCC configuration with CO_2 capture and sequestration presents technical and environmental advantages when compared to traditional technology. - Highlights: • We compared thermal cycles with the exergetic carbon exergy tax. • Thermal cycles with and without carbon capture and sequestration were considered. • Burned and gasified sugarcane bagasse was assumed as renewable fuel. • Exergetic carbon penalty tax was imposed to all studied configurations. • BIGCC with carbon sequestration revealed to be advantageous.

  9. An optimization method for gas refrigeration cycle based on the combination of both thermodynamics and entransy theory

    International Nuclear Information System (INIS)

    Chen, Qun; Xu, Yun-Chao; Hao, Jun-Hong

    2014-01-01

    Highlights: • An optimization method for practical thermodynamic cycle is developed. • The entransy-based heat transfer analysis and thermodynamic analysis are combined. • Theoretical relation between system requirements and design parameters is derived. • The optimization problem can be converted into conditional extremum problem. • The proposed method provides several useful optimization criteria. - Abstract: A thermodynamic cycle usually consists of heat transfer processes in heat exchangers and heat-work conversion processes in compressors, expanders and/or turbines. This paper presents a new optimization method for effective improvement of thermodynamic cycle performance with the combination of entransy theory and thermodynamics. The heat transfer processes in a gas refrigeration cycle are analyzed by entransy theory and the heat-work conversion processes are analyzed by thermodynamics. The combination of these two analysis yields a mathematical relation directly connecting system requirements, e.g. cooling capacity rate and power consumption rate, with design parameters, e.g. heat transfer area of each heat exchanger and heat capacity rate of each working fluid, without introducing any intermediate variable. Based on this relation together with the conditional extremum method, we theoretically derive an optimization equation group. Simultaneously solving this equation group offers the optimal structural and operating parameters for every single gas refrigeration cycle and furthermore provides several useful optimization criteria for all the cycles. Finally, a practical gas refrigeration cycle is taken as an example to show the application and validity of the newly proposed optimization method

  10. Search for the doubly charmed baryon Ξcc +

    NARCIS (Netherlands)

    Aaij, R.; Adeva, B.; Adinolfi, M.; Adrover, C.; Affolder, A.; Ajaltouni, Z.; Albrecht, J.; Alessio, F.; Alexander, M.; Ali, S.; Alkhazov, G.; Alvarez Cartelle, P.; Alves, A. A.; Amato, S.; Amerio, S.; Amhis, Y.; Anderlini, L.; Anderson, J.; Andreassen, P.R.; Andrews, J.E.; Appleby, R. B.; Aquines Gutierrez, O.; Archilli, F.; Artamonov, A.; Artuso, M.; Aslanides, E.; Auriemma, G.; Baalouch, M.; Bachmann, S.; Back, J. J.; Badalov, A.; Baesso, C.; Balagura, V.; Baldini, W.; Barlow, R. J.; Barschel, C.; Barsuk, S.; Barter, W.; Bauer, Th.; Bay, A.; Beddow, J.; Bedeschi, F.; Bediaga, I.; Belogurov, S.; Belous, K.; Belyaev, I.; Ben-Haim, E.; Bencivenni, G.; Benson, S.; Benton, J.; Berezhnoy, A.; Bernet, R.; Bettler, M-O.; Van Beuzekom, Martin; Bien, A.; Bifani, S.; Bird, T.D.; Bizzeti, A.; Bjørnstad, P. M.; Blake, T.; Blanc, F.; Blouw, J.; Blusk, S.; Bocci, V.; Bondar, A.; Bondar, N.; Bonivento, W.; Borghi, S.; Borgia, A.; Bowcock, T. J. V.; Bowen, E.; Bozzi, C.; Brambach, T.; Van Den Brand, J.; Bressieux, J.; Brett, D.; Britsch, M.; Britton, T.; Brook, N. H.; Brown, H.; Bursche, A.; Busetto, G.; Buytaert, J.; Cadeddu, S.; Callot, O.; Calvi, M.; Calvo Gomez, M.; Camboni, A.; Campana, P.; Campora Perez, D.; Carbone, A.; Carboni, G.; Cardinale, R.; Cardini, A.; Carranza-Mejia, H.; Carson, L.; Carvalho Akiba, K.; Casse, G.; Castillo Garcia, L.; Cattaneo, M.; Cauet, Ch; Cenci, R.; Charles, M.; Charpentier, Ph; Cheung, S-F.; Chiapolini, N.; Chrzaszcz, M.; Ciba, K.; Cid Vidal, X.; Ciezarek, G.; Clarke, P. E. L.; Clemencic, M.; Cliff, H. V.; Closier, J.; Coca-Pelaz, A.; Coco, V.; Cogan, J.; Cogneras, E.; Collins, P.; Comerma-Montells, A.; Contu, A.; Cook, A.; Coombes, M.; Coquereau, S.; Corti, G.; Couturier, B.; Cowan, G. A.; Craik, D. C.; Cruz Torres, M.; Cunliffe, S.; Currie, C.R.; D'Ambrosio, C.; David, P.; David, P.; Davis, A.; De Bonis, I.; De Bruyn, K.; De Capua, S.; De Cian, M.; de Miranda, J. M.; Paula, L.E.; da-Silva, W.S.; De Simone, P.; Decamp, D.; Deckenhoff, M.; Del Buono, L.; Déléage, N.; Derkach, D.; Deschamps, O.; Dettori, F.; Di Canto, A.; Dijkstra, H.; Dogaru, M.; Donleavy, S.; Dordei, F.; Dosil Suárez, A.; Dossett, D.; Dovbnya, A.; Dupertuis, F.; Durante, P.; Dzhelyadin, R.; Dziurda, A.; Dzyuba, A.; Easo, S.; Egede, U.; Egorychev, V.; Eidelman, S.; Van Eijk, D.; Eisenhardt, S.; Eitschberger, U.; Ekelhof, R.; Eklund, L.; El Rifai, I.; Elsasser, Ch.; Falabella, A.; Färber, C.; Farinelli, C.; Farry, S.; Ferguson, D.; Fernandez Albor, V.; Ferreira Rodrigues, F.; Ferro-Luzzi, M.; Filippov, S.; Fiore, M.; Fitzpatrick, C.; Fontana, Mark; Fontanelli, F.; Forty, R.; De Aguiar Francisco, O.; Frank, M.; Frei, C.; Frosini, M.; Furfaro, E.; Gallas Torreira, A.; Galli, D.; Gandelman, M.; Gandini, P.; Gao, Y.; Garofoli, J.; Garosi, P.; Garra Tico, J.; Garrido, L.; Carvalho-Gaspar, M.; Gauld, Rhorry; Gersabeck, E.; Gersabeck, M.; Gershon, T. J.; Ghez, Ph; Gibson, V.; Giubega, L.; Gligorov, V. V.; Göbel, C.; Golubkov, D.; Golutvin, A.; Gomes, A.Q.; Gorbounov, P.; Head-Gordon, Teresa; Grabalosa Gándara, M.; Graciani Diaz, R.; Granado Cardoso, L. A.; Graugés, E.; Graziani, G.; Grecu, A.; Greening, E.; Gregson, S.; Griffith, P.; Grillo, L.; Grünberg, O.; Gui, B.; Gushchin, E.; Guz, Yu; Gys, T.; Hadjivasiliou, C.; Haefeli, G.; Haen, C.; Haines, S. C.; Hall, S.; Hamilton, B.; Hampson, T.; Hansmann-Menzemer, S.; Harnew, N.; Harnew, S. T.; Harrison, J.; Hartmann, T.; He, J.; Head, T.; Heijne, V.; Hennessy, K.; Henrard, P.; Hernando Morata, J. A.; van Herwijnen, E.; Heß, M.; Hicheur, A.; Hicks, G.E.; Hill, D.; Hoballah, M.; Hombach, C.; Hulsbergen, W.; Hunt, P.; Huse, J.T.; Hussain, N.; Hutchcroft, D. E.; Hynds, D.; Iakovenko, V.; Idzik, M.; Ilten, P.; Jacobsson, R.; Jaeger, A.; Jans, E.; Jaton, P.; Jawahery, A.; Jing, F.; John, M.; Johnson, D.; Jones, C. R.; Joram, C.; Jost, B.; Kaballo, M.; Kandybei, S.; Kanso, W.; Karacson, M.; Karbach, T. M.; Kenyon, I. R.; Ketel, T.; Khanji, B.; Kochebina, O.; Komarov, I.; Koopman, R. F.; Koppenburg, P.; Korolev, M.; Kozlinskiy, A.; Kravchuk, L.; Kreplin, K.; Kreps, M.; Krocker, G.; Krokovny, P.; Kruse, F.; Kucharczyk, M.; Kudryavtsev, V.; Kurek, K.; Kvaratskheliya, T.; La Thi, V. N.; Lacarrere, D.; Lafferty, G. D.; Lai, A.; Lambert, D.M.; Lambert, R. W.; Lanciotti, E.; Lanfranchi, G.; Langenbruch, C.; Latham, T. E.; Lazzeroni, C.; Le Gac, R.; Van Leerdam, J.; Lees, J. P.; Lefèvre, R.; Leflat, A.; Lefrançois, J.; Di Leo, S.; Leroy, O.; Lesiak, T.; Leverington, B.; Li, Y.; Li Gioi, L.; Liles, M.; Lindner, R.; Linn, S.C.; Liu, B.; Liu, G.; Lohn, S.; Longstaff, I.; Lopes, J. H.; Lopez-March, N.; Lu, H.; Lucchesi, D.; Luisier, J.; Luo, H.; Lupton, O.; Machefert, F.; Machikhiliyan, I. V.; Maciuc, F.; Maev, O.; Malde, S.; Manca, G.; Mancinelli, G.; Maratas, J.; Marconi, U.; Marino, P.; Märki, R.; Marks, J.; Martellotti, G.; Martens, A.; Martín Sánchez, A.; Martinelli-Boneschi, F.; Martinez-Santos, D.; Martins Tostes, D.; Martynov, A.; Massafferri, A.; Matev, R.; Mathe, Z.; Matteuzzi, C.; Maurice, E.; Mazurov, A.; McCarthy, J.; Mcnab, A.; McNulty, R.; McSkelly, B.; Meadows, B. T.; Meier, F.; Meissner, M.; Merk, M.; Milanes, D. A.; Minard, M. N.; Molina Rodriguez, J.; Monteil, S.; Moran-Zenteno, D.; Morawski, P.; Mordà, A.; Morello, M. J.; Mountain, R.; Mous, I.; Muheim, F.; Müller, Karl; Muresan, R.; Muryn, B.; Muster, B.; Naik, P.; Nakada, T.; Nandakumar, R.; Nasteva, I.; Needham, M.; Neubert, S.; Neufeld, N.; Nguyen, A. D.; Nguyen, T. D.; Nguyen-Mau, C.; Nicol, M.; Niess, V.; Niet, R.; Nikitin, N.; Nikodem, T.; Nomerotski, A.; Novoselov, A.; Oblakowska-Mucha, A.; Obraztsov, V.; Oggero, S.; Ogilvy, S.; Okhrimenko, O.; Oldeman, R.; Orlandea, M.; Otalora Goicochea, J. M.; Owen, R.P.; Oyanguren, A.; Pal, B. K.; Palano, A.; Palutan, M.; Panman, J.; Papanestis, A.; Pappagallo, M.; Parkes, C.; Parkinson, C. J.; Passaleva, G.; Patel, G. D.; Patel, M.; Patrick, G. N.; Patrignani, C.; Pavel-Nicorescu, C.; Pazos Alvarez, A.; Pearce, D.A.; Pellegrino, A.; Penso, G.; Pepe Altarelli, M.; Perazzini, S.; Perez Trigo, E.; Pérez-Calero Yzquierdo, A.; Perret, P.; Perrin-Terrin, M.; Pescatore, L.; Pesen, E.; Pessina, G.; Petridis, K.; Petrolini, A.; Phan, A.; Picatoste Olloqui, E.; Pietrzyk, B.; Pilař, T.; Pinci, D.; Playfer, S.; Plo Casasus, M.; Polci, F.; Polok, G.; Poluektov, A.; Polycarpo, E.; Popov, A.; Popov, D.; Popovici, B.; Potterat, C.; Powell, A.; Prisciandaro, J.; Pritchard, C.A.; Prouve, C.; Pugatch, V.; Puig Navarro, A.; Punzi, G.; Qian, Y.W.; Rachwal, B.; Rademacker, J. H.; Rakotomiaramanana, B.; Rangel, M. S.; Raniuk, I.; Rauschmayr, N.; Raven, G.; Redford, S.; Reichert, S.; Reid, M.; dos Reis, A. C.; Ricciardi, S.; Richards, Al.; Rinnert, K.; Rives Molina, V.; Roa Romero, D. A.; Robbe, P.; Roberts, D. A.; Rodrigues, A. B.; Rodrigues, L.E.T.; Rodriguez Perez, P.; Roiser, S.; Romanovsky, V.; Romero Vidal, A.; Rotondo, M.; Rouvinet, J.; Ruf, T.; Ruffini, F.; Ruiz, van Hapere; Ruiz Valls, P.; Sabatino, G.; Saborido Silva, J. J.; Sagidova, N.; Sail, P.; Saitta, B.; Salustino Guimaraes, V.; Sanmartin Sedes, B.; Santacesaria, R.; Santamarina Rios, C.; Santovetti, E.; Sapunov, M.; Sarti, A.; Satriano, C.; Satta, A.; Savrie, M.; Savrina, D.; Schiller, M.; Schindler, R. H.; Schlupp, M.; Schmelling, M.; Schmidt, B.; Schneider, O.; Schopper, A.; Schune, M. H.; Schwemmer, R.; Sciascia, B.; Sciubba, A.; Seco, M.; Semennikov, A.; Senderowska, K.; Sepp, I.; Serra, N.; Serrano, J.; Seyfert, P.; Shapkin, M.; Shapoval, I.; Shcheglov, Y.; Shears, T.; Shekhtman, L.; Shevchenko, O.; Shevchenko, V.; Shires, A.; Silva Coutinho, R.; Sirendi, M.; Skidmore, N.; Skwarnicki, T.; Smith, N. A.; Smith, E.; Smith, E.; Smith, J; Smith, M.; Sokoloff, M. D.; Soler, F. J. P.; Soomro, F.; de Souza, D.K.; Souza De Paula, B.; Spaan, B.; Sparkes, A.; Spradlin, P.; Stagni, F.; Stahl, S.; Steinkamp, O.; Stevenson-Moore, P.; Stoica, S.; Stone, S.; Storaci, B.; Straticiuc, M.; Straumann, U.; Subbiah, V. K.; Sun, L.; Sutcliffe, W.; Swientek, S.; Syropoulos, V.; Szczekowski, M.; Szczypka, P.; Szilard, D.; Szumlak, T.; T'Jampens, S.; Teklishyn, M.; Teodorescu, E.; Teubert, F.; Thomas, C.; Thomas, E.; Van Tilburg, J.; Tisserand, V.; Tobin, M. N.; Tolk, S.; Tonelli, D.; Topp-Joergensen, S.; Torr, N.; Tournefier, E.; Tourneur, S.; Tran, N.T.M.T.; Tresch, M.; Tsaregorodtsev, A.; Tsopelas, P.; Tuning, N.; Ubeda Garcia, M.; Ukleja, A.; Ustyuzhanin, A.; Uwer, U.; Vagnoni, V.; Valenti, G.; Vallier, A.; Vazquez Gomez, R.; Vazquez Regueiro, P.; Vázquez Sierra, C.; Vecchi, S.; Velthuis, M.J.; Veltri, M.; Veneziano, G.; Vesterinen, M.; Viaud, B.; Vieira, D.; Vilasis-Cardona, X.; Vollhardt, A.; Volyanskyy, D.; Voong, D.; Vorobyev, A.; Vorobyev, V.; Voß, C.; Voss, H.; Waldi, R.; Wallace, C.; Wallace, R.; Wandernoth, S.; Wang, J.; Ward, D. R.; Watson, N. K.; Webber, A. D.; Websdale, D.; Whitehead, M.; Wicht, J.; Wiechczynski, J.; Wiedner, D.; Wiggers, L.; Wilkinson, G.; Williams, M.P.; Williams, M.; Wilson, James F; Wimberley, J.; Wishahi, J.; Wislicki, W.; Witek, M.; Wormser, G.; Wotton, S. A.; Wright, S.J.; Wu, S.; Wyllie, K.; Xie, Y.; Xing, Z.; Yang, Z.; Yuan, X.; Yushchenko, O.; Zangoli, M.; Zavertyaev, M.; Zhang, F.; Zhang, L.; Zhang, W. C.; Zhang, Y.; Zhelezov, A.; Zhokhov, A.; Zhong, L.; Zvyagin, A.

    2013-01-01

    A search for the doubly charmed baryon Ξcc + in the decay mode Ξcc + → Λc +K-π+ is performed with a data sample, corresponding to an integrated luminosity of 0.65 fb-1, of pp collisions recorded at a centre-of-mass energy of 7TeV. No significant signal is found in the mass range 3300-3800 MeV/c2.

  11. Analysis of energetic and exergetic efficiency, and environmental benefits of biomass integrated gasification combined cycle technology.

    Science.gov (United States)

    Mínguez, María; Jiménez, Angel; Rodríguez, Javier; González, Celina; López, Ignacio; Nieto, Rafael

    2013-04-01

    The problem of the high carbon dioxide emissions linked to power generation makes necessary active research on the use of biofuels in gas turbine systems as a promising alternative to fossil fuels. Gasification of biomass waste is particularly of interest in obtaining a fuel to be run in gas turbines, as it is an efficient biomass-to-biofuel conversion process, and an integration into a combined cycle power plant leads to a high performance with regard to energetic efficiency. The goal of this study was to carry out an energetic, exergetic and environmental analysis of the behaviour of an integrated gasification combined cycle (IGCC) plant fuelled with different kinds of biomass waste by means of simulations. A preliminary economic study is also included. Although a technological development in gasification technology is necessary, the results of simulations indicate a high technical and environmental interest in the use of biomass integrated gasification combined cycle (BioIGCC) systems for large-scale power generation from biomass waste.

  12. Efficient C/C++ programming smaller, faster, better

    CERN Document Server

    Heller, Steve

    1994-01-01

    Efficient C/C++ Programming describes a practical, real-world approach to efficient C/C++ programming. Topics covered range from how to save storage using a restricted character set and how to speed up access to records by employing hash coding and caching. A selective mailing list system is used to illustrate rapid access to and rearrangement of information selected by criteria specified at runtime.Comprised of eight chapters, this book begins by discussing factors to consider when deciding whether a program needs optimization. In the next chapter, a supermarket price lookup system is used to

  13. Energy Conversion Alternatives Study (ECAS), Westinghouse phase 1. Volume 5: Combined gas-steam turbine cycles. [energy conversion efficiency in electric power plants

    Science.gov (United States)

    Amos, D. J.; Foster-Pegg, R. W.; Lee, R. M.

    1976-01-01

    The energy conversion efficiency of gas-steam turbine cycles was investigated for selected combined cycle power plants. Results indicate that it is possible for combined cycle gas-steam turbine power plants to have efficiencies several point higher than conventional steam plants. Induction of low pressure steam into the steam turbine is shown to improve the plant efficiency. Post firing of the boiler of a high temperature combined cycle plant is found to increase net power but to worsen efficiency. A gas turbine pressure ratio of 12 to 1 was found to be close to optimum at all gas turbine inlet temperatures that were studied. The coal using combined cycle plant with an integrated low-Btu gasifier was calculated to have a plant efficiency of 43.6%, a capitalization of $497/kW, and a cost of electricity of 6.75 mills/MJ (24.3 mills/kwh). This combined cycle plant should be considered for base load power generation.

  14. Evaluation of the energy efficiency of combined cycle gas turbine. Case study of Tashkent thermal power plant, Uzbekistan

    International Nuclear Information System (INIS)

    Aminov, Zarif; Nakagoshi, Nobukazu; Xuan, Tran Dang; Higashi, Osamu; Alikulov, Khusniddin

    2016-01-01

    Highlights: • The combined cycle power plant (CCPP) has a steam turbine and a gas turbine. • Fossil fuel savings and reduction of the CCGT of was evaluated. • The performance of a three pressure CCGT is modelled under different modes. • Energy efficiency of the combined cycle was 58.28%. • An annual reduction of 1760.18 tNO_x/annum and 981.25 ktCO_2/annum can be achieved. - Abstract: The power generation of Tashkent Thermal Power Plant (TPP) is based on conventional power units. Moreover, the facility suffers from limited efficiency in electricity generation. The plant was constructed during the Soviet era. Furthermore, the power plant is being used for inter-hour power generation regulation. As a result, the efficiency can be reduced by increasing specific fuel consumption. This research focuses on the evaluation of the energy efficiency of the combined cycle gas turbine (CCGT) for the Tashkent TPP. Specifically, the objective is an evaluation of fossil fuel savings and reduction of CO_2 and NO_x emissions with the using CCGT technology at conventional power plant. The proposed combined cycle power plant (CCPP) includes an existing steam turbine (ST) with 160 MW capacity, heat recovery steam generator (HRSG), and gas turbine (GT) technology with 300 MW capacity. The performance of a three pressure CCGT is modelled under different modes. As a result, the efficiency of the combined cycle was evaluated at 58.28%, while the conventional cycle had an efficiency of 34.5%. We can achieve an annual reduction of 1760.18 tNO_x/annum and 981.25 ktCO_2/annum.

  15. Evaluation of Indirect Combined Cycle in Very High Temperature Gas--Cooled Reactor

    International Nuclear Information System (INIS)

    Chang Oh; Robert Barner; Cliff Davis; Steven Sherman; Paul Pickard

    2006-01-01

    The U.S. Department of Energy and Idaho National Laboratory are developing a very high temperature reactor to serve as a demonstration of state-of-the-art nuclear technology. The purpose of the demonstration is twofold: (a) efficient, low-cost energy generation and (b) hydrogen production. Although a next-generation plant could be developed as a single-purpose facility, early designs are expected to be dual purpose, as assumed here. A dual-purpose design with a combined cycle of a Brayton top cycle and a bottom Rankine cycle was investigated. An intermediate heat transport loop for transporting heat to a hydrogen production plant was used. Helium, CO2, and a helium-nitrogen mixture were studied to determine the best working fluid in terms of the cycle efficiency. The relative component sizes were estimated for the different working fluids to provide an indication of the relative capital costs. The relative size of the turbomachinery was measured by comparing the power input/output of the component. For heat exchangers the volume was computed and compared. Parametric studies away from the baseline values of the cycle were performed to determine the effects of varying conditions in the cycle. This gives some insight into the sensitivity of the cycle to various operating conditions as well as trade-offs between efficiency and component size. Parametric studies were carried out on reactor outlet temperature, mass flow, pressure, and turbine cooling

  16. New pressure control method of mixed gas in a combined cycle power plant of a steel mill

    Science.gov (United States)

    Xie, Yudong; Wang, Yong

    2017-08-01

    The enterprise production concept is changing with the development of society. A steel mill requires a combined-cycle power plant, which consists of both a gas turbine and steam turbine. It can recycle energy from the gases that are emitted from coke ovens and blast furnaces during steel production. This plant can decrease the overall energy consumption of the steel mill and reduce pollution to our living environment. To develop a combined-cycle power plant, the pressure in the mixed-gas transmission system must be controlled in the range of 2.30-2.40 MPa. The particularity of the combined-cycle power plant poses a challenge to conventional controllers. In this paper, a composite control method based on the Smith predictor and cascade control was proposed for the pressure control of the mixed gases. This method has a concise structure and can be easily implemented in actual industrial fields. The experiment has been conducted to validate the proposed control method. The experiment illustrates that the proposed method can suppress various disturbances in the gas transmission control system and sustain the pressure of the gas at the desired level, which helps to avoid abnormal shutdowns in the combined-cycle power plant.

  17. Thermodynamic analysis of an integrated gasification solid oxide fuel cell plant combined with an organic Rankine cycle

    DEFF Research Database (Denmark)

    Pierobon, Leonardo; Rokni, Masoud; Larsen, Ulrik

    2013-01-01

    into a fixed bed gasification plant to produce syngas which fuels the combined solid oxide fuel cells e organic Rankine cycle system to produce electricity. More than a hundred fluids are considered as possible alternative for the organic cycle using non-ideal equations of state (or state-of-the-art equations......A 100 kWe hybrid plant consisting of gasification system, solid oxide fuel cells and organic Rankine cycle is presented. The nominal power is selected based on cultivation area requirement. For the considered output a land of around 0.5 km2 needs to be utilized. Woodchips are introduced...... achieved by simple and double stage organic Rankine cycle plants and around the same efficiency of a combined gasification, solid oxide fuel cells and micro gas turbine plant. © 2013 Elsevier Ltd. All rights reserved....

  18. Thermodynamic and design considerations of organic Rankine cycles in combined application with a solar thermal gas turbine

    Science.gov (United States)

    Braun, R.; Kusterer, K.; Sugimoto, T.; Tanimura, K.; Bohn, D.

    2013-12-01

    Concentrated Solar Power (CSP) technologies are considered to provide a significant contribution for the electric power production in the future. Different kinds of technologies are presently in operation or under development, e.g. parabolic troughs, central receivers, solar dish systems and Fresnel reflectors. This paper takes the focus on central receiver technologies, where the solar radiation is concentrated by a field of heliostats in a receiver on the top of a tall tower. To get this CSP technology ready for the future, the system costs have to reduce significantly. The main cost driver in such kind of CSP technologies are the huge amount of heliostats. To reduce the amount of heliostats, and so the investment costs, the efficiency of the energy conversion cycle becomes an important issue. An increase in the cycle efficiency results in a decrease of the solar heliostat field and thus, in a significant cost reduction. The paper presents the results of a thermodynamic model of an Organic Rankine Cycle (ORC) for combined cycle application together with a solar thermal gas turbine. The gas turbine cycle is modeled with an additional intercooler and recuperator and is based on a typical industrial gas turbine in the 2 MW class. The gas turbine has a two stage radial compressor and a three stage axial turbine. The compressed air is preheated within a solar receiver to 950°C before entering the combustor. A hybrid operation of the gas turbine is considered. In order to achieve a further increase of the overall efficiency, the combined operation of the gas turbine and an Organic Rankine Cycle is considered. Therefore an ORC has been set up, which is thermally connected to the gas turbine cycle at two positions. The ORC can be coupled to the solar-thermal gas turbine cycle at the intercooler and after the recuperator. Thus, waste heat from different cycle positions can be transferred to the ORC for additional production of electricity. Within this investigation

  19. Modern combined cycle power plant utilizing the GT11N2

    International Nuclear Information System (INIS)

    Goodwin, J.C.

    1992-01-01

    The requirement imposed on modern power plants are increasingly demanding. The limits of: efficiency; environmental sensitivity; reliability and availability; are constantly being pushed. Today's state of the art combined cycle power plants are positioned well to meet these challenges. This paper reports that these objectives can be achieved through the selection of the proper gas turbine generator in an optimized cycle concept. A balanced approach to the plant design is required. It must not sacrifice any one of these requirements, in order to achieve the others. They achieve their fullest potential when firing a clean fuel, natural gas. However, fuel oil, both light (No. 2) and heavy (No. 6), can be utilized but some efficiency and environmental impact will have to be sacrificed

  20. Thermal characteristics of combined thermoelectric generator and refrigeration cycle

    International Nuclear Information System (INIS)

    Yilbas, Bekir S.; Sahin, Ahmet Z.

    2014-01-01

    Highlights: • TEM location in between the evaporator and condenser results in low coefficient of performance. • TEM location in between condenser and its ambient improves coefficient of performance of the combined system. • High temperature ratio enhances coefficient of performance of combined system. • Certain values of parameters enhance combined system performance. - Abstract: A combined thermal system consisting of a thermoelectric generator and a refrigerator is considered and the effect of location of the thermoelectric generator, in the refrigeration cycle, on the performance characteristics of the combined system is investigated. The operating conditions and their influence on coefficient of performance of the combined system are examined through introducing the dimensionless parameters, such as λ(λ = Q HTE /Q H , where Q HTE is heat transfer to the thermoelectric generator from the condenser, Q H is the total heat transfer from the condenser to its ambient), temperature ratio (θ L = T L /T H , where T L is the evaporator temperature and T H is the condenser temperature), r C (r C = C L /C H , where C L is the thermal capacitance due to heat transfer to evaporator and C H , is the thermal capacitance due to heat rejected from the condenser), θ W (θ W = T W /T H , where T W is the ambient temperature), θ C (θ C = T C /T H , where T C is the cold space temperature). It is found that the location of the thermoelectric generator in between the condenser and the evaporator decreases coefficient of performance of the combined system. Alternatively, the location of thermoelectric device in between the condenser and its ambient enhances coefficient of performance of the combined system. The operating parameters has significant effect on the performance characteristics of the combined system; in which case temperature ratio (θ L ) within the range of 0.68–0.70, r C = 2.5, θ W = 0.85, and θ C = 0.8 improve coefficient of performance of the

  1. Performance analysis of a bio-gasification based combined cycle power plant employing indirectly heated humid air turbine

    Energy Technology Data Exchange (ETDEWEB)

    Mukherjee, S., E-mail: sankha.deepp@gmail.com; Mondal, P., E-mail: mondal.pradip87@gmail.com; Ghosh, S., E-mail: sudipghosh.becollege@gmail.com [Department of Mechanical Engineering, Indian Institute of Engineering Science and Technology, Shibpur, Howrah – 711103, West Bengal (India)

    2016-07-12

    Rapid depletion of fossil fuel has forced mankind to look into alternative fuel resources. In this context, biomass based power generation employing gas turbine appears to be a popular choice. Bio-gasification based combined cycle provides a feasible solution as far as grid-independent power generation is concerned for rural electrification projects. Indirectly heated gas turbine cycles are promising alternatives as they avoid downstream gas cleaning systems. Advanced thermodynamic cycles have become an interesting area of study to improve plant efficiency. Water injected system is one of the most attractive options in this field of applications. This paper presents a theoretical model of a biomass gasification based combined cycle that employs an indirectly heated humid air turbine (HAT) in the topping cycle. Maximum overall electrical efficiency is found to be around 41%. Gas turbine specific air consumption by mass is minimum when pressure ratio is 6. The study reveals that, incorporation of the humidification process helps to improve the overall performance of the plant.

  2. Application of C/C composites to the combustion chamber of rocket engines. Part 1: Heating tests of C/C composites with high temperature combustion gases

    Science.gov (United States)

    Tadano, Makoto; Sato, Masahiro; Kuroda, Yukio; Kusaka, Kazuo; Ueda, Shuichi; Suemitsu, Takeshi; Hasegawa, Satoshi; Kude, Yukinori

    1995-04-01

    Carbon fiber reinforced carbon composite (C/C composite) has various superior properties, such as high specific strength, specific modulus, and fracture strength at high temperatures of more than 1800 K. Therefore, C/C composite is expected to be useful for many structural applications, such as combustion chambers of rocket engines and nose-cones of space-planes, but C/C composite lacks oxidation resistivity in high temperature environments. To meet the lifespan requirement for thermal barrier coatings, a ceramic coating has been employed in the hot-gas side wall. However, the main drawback to the use of C/C composite is the tendency for delamination to occur between the coating layer on the hot-gas side and the base materials on the cooling side during repeated thermal heating loads. To improve the thermal properties of the thermal barrier coating, five different types of 30-mm diameter C/C composite specimens constructed with functionally gradient materials (FGM's) and a modified matrix coating layer were fabricated. In this test, these specimens were exposed to the combustion gases of the rocket engine using nitrogen tetroxide (NTO) / monomethyl hydrazine (MMH) to evaluate the properties of thermal and erosive resistance on the thermal barrier coating after the heating test. It was observed that modified matrix and coating with FGM's are effective in improving the thermal properties of C/C composite.

  3. Multihospital Occurrence of Pan-Resistant Klebsiella pneumoniae Sequence Type 147 with an ISEcp1-Directed blaOXA-181 Insertion in the mgrB Gene in the United Arab Emirates.

    Science.gov (United States)

    Sonnevend, Ágnes; Ghazawi, Akela; Hashmey, Rayhan; Haidermota, Aliasgher; Girgis, Safinaz; Alfaresi, Mubarak; Omar, Mohammed; Paterson, David L; Zowawi, Hosam M; Pál, Tibor

    2017-07-01

    The emergence of pan-resistant Klebsiella pneumoniae strains is an increasing concern. In the present study, we describe a cluster of 9 pan-resistant K. pneumoniae sequence type 147 (ST147) isolates encountered in 4 patients over nearly 1 year in 3 hospitals of the United Arab Emirates (UAE). The isolates exhibited highly similar genotypes. All produced chromosomally encoded OXA-181, and the majority also produced the NDM-5 carbapenemase. As with the previously described single isolate from the UAE, MS6671, the mgrB was disrupted by a functional, IS Ecp1 -driven bla OXA-181 insertion causing resistance to carbapenems. The mutation was successfully complemented with an intact mgrB gene, indicating that it was responsible for colistin resistance. bla NDM-5 was located within a resistance island of an approximately 100-kb IncFII plasmid carrying ermB , mph (A), bla TEM-1B , rmtB , bla NDM-5 , sul1 , aadA2 , and dfrA12 resistance genes. Sequencing this plasmid (pABC143-NDM) revealed that its backbone was nearly identical to that of plasmid pMS6671E from which several resistance genes, including bla NDM-5 , had been deleted. More extensive similarities of the backbone and the resistance island were found between pABC143C-NDM and the bla NDM-5 -carrying IncFII plasmids of two K. pneumoniae ST147 isolates from South Korea, one of which was colistin resistant, and both also produced OXA-181. Notably, one of these strains was isolated from a patient transferred from the UAE. Our data show that this pan-resistant clone has an alarming capacity to maintain itself over an extended period of time and is even likely to be transmitted internationally. Copyright © 2017 American Society for Microbiology.

  4. Generating power at high efficiency combined cycle technology for sustainable energy production

    CERN Document Server

    Jeffs, E

    2008-01-01

    Combined cycle technology is used to generate power at one of the highest levels of efficiency of conventional power plants. It does this through primary generation from a gas turbine coupled with secondary generation from a steam turbine powered by primary exhaust heat. Generating power at high efficiency thoroughly charts the development and implementation of this technology in power plants and looks to the future of the technology, noting the advantages of the most important technical features - including gas turbines, steam generator, combined heat and power and integrated gasification com

  5. Base-Load and Peak Electricity from a Combined Nuclear Heat and Fossil Combined-Cycle Plant

    International Nuclear Information System (INIS)

    Conklin, Jim; Forsberg, Charles W.

    2007-01-01

    A combined-cycle power plant is proposed that uses heat from a high-temperature reactor and fossil fuel to meet base-load and peak electrical demands. The high-temperature gas turbine produces shaft power to turn an electric generator. The hot exhaust is then fed to a heat recovery steam generator (HRSG) that provides steam to a steam turbine for added electrical power production. A simplified computational model of the thermal power conversion system was developed in order to parametrically investigate two different steady-state operation conditions: base load nuclear heat only from an Advanced High Temperature Reactor (AHTR), and combined nuclear heat with fossil heat to increase the turbine inlet temperature. These two cases bracket the expected range of power levels, where any intermediate power level can result during electrical load following. The computed results indicate that combined nuclear-fossil systems have the potential to offer both low-cost base-load electricity and lower-cost peak power relative to the existing combination of base-load nuclear plants and separate fossil-fired peak-electricity production units. In addition, electric grid stability, reduced greenhouse gases, and operational flexibility can also result with using the conventional technology presented here for the thermal power conversion system coupled with the AHTR

  6. Alteration of the exopolysaccharide production and the transcriptional profile of free-living Frankia strain CcI3 under nitrogen-fixing conditions.

    Science.gov (United States)

    Lee, Hae-In; Donati, Andrew J; Hahn, Dittmar; Tisa, Louis S; Chang, Woo-Suk

    2013-12-01

    We investigated the effect of different nitrogen (N) sources on exopolysaccharide (EPS) production and composition by Frankia strain CcI3, a N2-fixing actinomycete that forms root nodules with Casuarina species. Frankia cells grown in the absence of NH4Cl (i.e., under N2-fixing conditions) produced 1.7-fold more EPS, with lower galactose (45.1 vs. 54.7 mol%) and higher mannose (17.3 vs. 9.7 mol%) contents than those grown in the presence of NH4Cl as a combined N-source. In the absence of the combined N-source, terminally linked and branched residue contents were nearly twice as high with 32.8 vs. 15.1 mol% and 15.1 vs. 8.7 mol%, respectively, than in its presence, while the content of linearly linked residues was lower with 52.1 mol% compared to 76.2 mol%. To find out clues for the altered EPS production at the transcriptional level, we performed whole-gene expression profiling using quantitative reverse transcription PCR and microarray technology. The transcription profiles of Frankia strain CcI3 grown in the absence of NH4Cl revealed up to 2 orders of magnitude higher transcription of nitrogen fixation-related genes compared to those of CcI3 cells grown in the presence of NH4Cl. Unexpectedly, microarray data did not provide evidence for transcriptional regulation as a mechanism for differences in EPS production. These findings indicate effects of nitrogen fixation on the production and composition of EPS in Frankia strain CcI3 and suggest posttranscriptional regulation of enhanced EPS production in the absence of the combined N-source.

  7. Combined cycles for pipeline compressor drives using heat

    International Nuclear Information System (INIS)

    Malewski, W.F.; Holldorff, G.M.

    1979-01-01

    Combined cycles for pipeline-booster stations using waste heat from gas turbines exhaust can improve the overall efficiency of such stations remarkably. Several working fluids are suitable. Due to existing criteria for selecting a working medium under mentioned conditions, water, ammonia, propane and butane can be considered as practical working fluids. The investigations have shown that: (1) ammonia is advantageous at low exhaust gas and ambient temperatures, (2) water is most effective at high exhaust gas and ambient temperatures, and (3), additionally, hydrocarbons are suitable in a medium range for exhaust gas and condensing temperatures. Not only thermodynamic but also operational features have to be considered. There is not one optimum working fluid but a best one suitable according to the prevailing site conditions

  8. Influence of precooling cooling air on the performance of a gas turbine combined cycle

    Energy Technology Data Exchange (ETDEWEB)

    Kwon, Ik Hwan; Kang, Do Won; Kang, Soo Young; Kim, Tong Seop [Inha Univ., Incheon (Korea, Republic of)

    2012-02-15

    Cooling of hot sections, especially the turbine nozzle and rotor blades, has a significant impact on gas turbine performance. In this study, the influence of precooling of the cooling air on the performance of gas turbines and their combined cycle plants was investigated. A state of the art F class gas turbine was selected, and its design performance was deliberately simulated using detailed component models including turbine blade cooling. Off design analysis was used to simulate changes in the operating conditions and performance of the gas turbines due to precooling of the cooling air. Thermodynamic and aerodynamic models were used to simulate the performance of the cooled nozzle and rotor blade. In the combined cycle plant, the heat rejected from the cooling air was recovered at the bottoming steam cycle to optimize the overall plant performance. With a 200K decrease of all cooling air stream, an almost 1.78% power upgrade due to increase in main gas flow and a 0.70 percent point efficiency decrease due to the fuel flow increase to maintain design turbine inlet temperature were predicted.

  9. Polarizable Embedded RI-CC2 Method for Two-Photon Absorption Calculations

    DEFF Research Database (Denmark)

    Hršak, Dalibor; Khah, Alireza Marefat; Christiansen, Ove

    2015-01-01

    We present a novel polarizable embedded resolution-of-identity coupled cluster singles and approximate doubles (PERI-CC2) method for calculation of two-photon absorption (TPA) spectra of large molecular systems. The method was benchmarked for three types of systems: a water-solvated molecule...... of formamide, a uracil molecule in aqueous solution, and a set of mutants of the channelrhodopsin (ChR) protein. The first test case shows that the PERI-CC2 method is in excellent agreement with the PE-CC2 method and in good agreement with the PE-CCSD method. The uracil test case indicates that the effects...... of hydrogen bonding on the TPA of a chromophore with the nearest environment is well-described with the PERI-CC2 method. Finally, the ChR calculation shows that the PERI-CC2 method is well-suited and efficient for calculations on proteins with medium-sized chromophores....

  10. A novel nuclear combined power and cooling system integrating high temperature gas-cooled reactor with ammonia–water cycle

    International Nuclear Information System (INIS)

    Luo, Chending; Zhao, Fuqiang; Zhang, Na

    2014-01-01

    Highlights: • We propose a novel nuclear ammonia–water power and cooling cogeneration system. • The high temperature reactor is inherently safe, with exhaust heat fully recovered. • The thermal performances are improved compared with nuclear combined cycle. • The base case attains an energy efficiency of 69.9% and exergy efficiency of 72.5%. • Energy conservation and emission reduction are achieved in this cogeneration way. - Abstract: A nuclear ammonia–water power and refrigeration cogeneration system (NAPR) has been proposed and analyzed in this paper. It consists of a closed high temperature gas-cooled reactor (HTGR) topping Brayton cycle and a modified ammonia water power/refrigeration combined bottoming cycle (APR). The HTGR is an inherently safe reactor, and thus could be stable, flexible and suitable for various energy supply situation, and its exhaust heat is fully recovered by the mixture of ammonia and water in the bottoming cycle. To reduce exergy losses and enhance outputs, the ammonia concentrations of the bottoming cycle working fluid are optimized in both power and refrigeration processes. With the HTGR of 200 MW thermal capacity and 900 °C/70 bar reactor-core-outlet helium, the system achieves 88.8 MW net electrical output and 9.27 MW refrigeration capacity, and also attains an energy efficiency of 69.9% and exergy efficiency of 72.5%, which are higher by 5.3%-points and 2.6%-points as compared with the nuclear combined cycle (NCC, like a conventional gas/steam power-only combined cycle while the topping cycle is a closed HTGR Brayton cycle) with the same nuclear energy input. Compared with conventional separate power and refrigeration generation systems, the fossil fuel saving (based on CH 4 ) and CO 2 emission reduction of base-case NAPR could reach ∼9.66 × 10 4 t/y and ∼26.6 × 10 4 t/y, respectively. The system integration accomplishes the safe and high-efficiency utilization of nuclear energy by power and refrigeration

  11. Wire-type MnO2/Multilayer graphene/Ni electrode for high-performance supercapacitors

    Science.gov (United States)

    Hu, Minglei; Liu, Yuhao; Zhang, Min; Wei, Helin; Gao, Yihua

    2016-12-01

    Commercially available wearable energy storage devices need a wire-type electrode with high strength, conductivity and electrochemical performance, as well as stable structure under deformation. Herein, we report a novel wire-type electrode of hierarchically structure MnO2 on Ni wire with multilayer graphene (MGr) as a buffer layer to enhance the electrical conductivity of the MnO2 and interface contact between the MnO2 and Ni wire. Thus, the wire-type MnO2/MGr/Ni electrode has a stable and high quality interface. The wire-type supercapacitor (WSC) based on wire-type MnO2/MGr/Ni electrode exhibits good electrochemical performance, high rate capability, extraordinary flexibility, and superior cycle lifetime. Length (area, volumetric) specific capacitance of the WSC reaches 6.9 mF cm-1 (73.2 mF cm-2, 9.8 F cm-3). Maximum length (volumetric) energy density of the WSC based on MnO2/MGr/Ni reaches 0.62 μWh cm-1 (0.88 mWh cm-3). Furthermore, the WSC has a short time constant (0.5-400 ms) and exhibits minimal change in capacitance under different bending shapes.

  12. Analysis of the effects of combining air separation with combustion in a zero emissions (ZEITMOP) cycle

    International Nuclear Information System (INIS)

    Foy, Kirsten; McGovern, Jim

    2007-01-01

    The ZEITMOP cycle is a zero emissions (oxyfuel) power plant cycle proposed by Evgeny Yantovski that uses oxygen ion transport membranes to extract the oxygen required for combustion from air. A current proposed configuration of the cycle requires an oxygen ion transport membrane air separation unit operating at 920 deg. C and a separate combustion chamber operating at 1400 deg. C. If oxygen is consumed by a chemical reaction on the permeate side of an oxygen transport membrane, the oxygen flux is larger, so the air separation unit can be physically smaller. In addition, if this reaction is exothermic, the air separation unit is heated by the reaction, requiring no additional heating. Combustion fulfils both of these requirements, so combustion in the oxygen transport membrane air separation unit would allow a smaller air separation unit, which would also act as a combustion chamber. Unfortunately, a combustion temperature of 1400 deg. C will damage most oxygen transport membranes available today. However, new materials are continually being developed and investigated, so it may be possible to have an oxygen transport membrane chamber operating at 1400 deg. C in the short to medium term future. Alternatively the combustion chamber may be cooled, allowing it to operate at more realistic temperatures for currently available oxygen transport membranes. Controlling the operation temperature of the combined unit requires changing the mass flow rates of various streams of fluid in the cycle. This will have an effect on the work and heat transfers in the cycle. It is possible to calculate the theoretical effects of these changes in temperature. This paper presents an analysis investigating the impact of combining the air separator and the combustion chamber. The efficiency of the cycle was calculated at various operation temperatures for the combined oxygen transport membrane combustion chamber. The results were compared to the efficiency of the current cycle. The changes

  13. Cell volume regulation in hemoglobin CC and AA erythrocytes

    International Nuclear Information System (INIS)

    Berkowitz, L.R.; Orringer, E.P.

    1987-01-01

    Swelling hemoglobin CC erythrocytes stimulates a ouabain-insensitive K flux that restores original cell volume. Studies were performed with the K analog, 86 Rb. This volume regulatory pathway was characterized for its anion dependence, sensitivity to loop diuretics, and requirement for Na. The swelling-induced K flux was eliminated if intracellular chloride was replaced by nitrate and both swelling-activated K influx and efflux were partially inhibited by 1 mM furosemide or bumetanide. K influx in swollen hemoglobin CC cells was not diminished when Na in the incubation medium was replaced with choline, indicating Na independence of the swelling-induced flux. Identical experiments with hemoglobin AA cells also demonstrated a swelling-induced increase in K flux, but the magnitude and duration of this increase were considerably less than that seen with hemoglobin CC cells. The increased K flux in hemoglobin AA cells was likewise sensitive to anion replacement and to loop diuretics and did not require the presence of Na. These data indicate that a volume-activated K pathway with similar transport characteristics exists in both hemoglobin CC and AA red cells

  14. Investigation of thermodynamic performances for two solar-biomass hybrid combined cycle power generation systems

    International Nuclear Information System (INIS)

    Liu, Qibin; Bai, Zhang; Wang, Xiaohe; Lei, Jing; Jin, Hongguang

    2016-01-01

    Highlights: • Two solar-biomass hybrid combined cycle power generation systems are proposed. • The characters of the two proposed systems are compared. • The on-design and off-design properties of the system are numerically investigated. • The favorable performances of thermochemical hybrid routine are validated. - Abstract: Two solar-biomass hybrid combined cycle power generation systems are proposed in this work. The first system employs the thermochemical hybrid routine, in which the biomass gasification is driven by the concentrated solar energy, and the gasified syngas as a solar fuel is utilized in a combined cycle for generating power. The second system adopts the thermal integration concept, and the solar energy is directly used to heat the compressed air in the topping Brayton cycle. The thermodynamic performances of the developed systems are investigated under the on-design and off-design conditions. The advantages of the hybrid utilization technical mode are demonstrated. The solar energy can be converted and stored into the chemical fuel by the solar-biomass gasification, with the net solar-to-fuel efficiency of 61.23% and the net solar share of 19.01% under the specific gasification temperature of 1150 K. Meanwhile, the proposed system with the solar thermochemical routine shows more favorable behaviors, the annual system overall energy efficiency and the solar-to-electric efficiency reach to 29.36% and 18.49%, while the with thermal integration concept of 28.03% and 15.13%, respectively. The comparison work introduces a promising approach for the efficient utilization of the abundant solar and biomass resources in the western China, and realizes the mitigation of CO_2 emission.

  15. Improving Forecast Skill by Assimilation of AIRS Cloud Cleared Radiances RiCC

    Science.gov (United States)

    Susskind, Joel; Rosenberg, Robert I.; Iredell, Lena

    2015-01-01

    ECMWF, NCEP, and GMAO routinely assimilate radiosonde and other in-situ observations along with satellite IR and MW Sounder radiance observations. NCEP and GMAO use the NCEP GSI Data Assimilation System (DAS).GSI DAS assimilates AIRS, CrIS, IASI channel radiances Ri on a channel-by-channel, case-by-case basis, only for those channels i thought to be unaffected by cloud cover. This test excludes Ri for most tropospheric sounding channels under partial cloud cover conditions. AIRS Version-6 RiCC is a derived quantity representative of what AIRS channel i would have seen if the AIRS FOR were cloud free. All values of RiCC have case-by-case error estimates RiCC associated with them. Our experiments present to the GSI QCd values of AIRS RiCC in place of AIRS Ri observations. GSI DAS assimilates only those values of RiCC it thinks are cloud free. This potentially allows for better coverage of assimilated QCd values of RiCC as compared to Ri.

  16. Identification and expression analysis of a CC chemokine from cobia (Rachycentron canadum).

    Science.gov (United States)

    Feng, Juan; Su, Youlu; Guo, Zhixun; Xu, Liwen; Sun, Xiuxiu; Wang, Yunxin

    2013-06-01

    Chemokines are small, secreted cytokine peptides known principally for their ability to induce migration and activation of leukocyte populations and regulate the immune response mechanisms. The cobia (Rachycentron canadum), a marine finfish species, has a great potential for net cage aquaculture in the South China Sea. We isolated and characterized a CC chemokine cDNA from cobia-designated RcCC2. Its cDNA is 783 bp in length and encodes a putative protein of 110 amino acids. Homology and phylogenetic analysis revealed that the RcCC2 gene, which contains four conserved cysteine residues, shares a high degree of similarity with other known CC chemokine sequences and is closest to the CCL19/21 clade. The mRNA of RcCC2 is expressed constitutively in all tested tissues, including gill, liver, muscle, spleen, kidney, head kidney, skin, brain, stomach, intestine and heart, but not blood, with the highest level of expression in gill and liver. The reverse transcription quantitative polymerase chain reaction was used to examine the expression of the RcCC2 gene in immune-related tissues, including head kidney, spleen and liver, following intraperitoneal injection of the viral mimic polyriboinosinic polyribocytidylic acid, formalin-killed Vibrio carchariae (bacterial vaccine) and phosphate-buffered saline as a control. RcCC2 gene expression was up-regulated differentially in head kidney, spleen and liver during 12 h after challenge. These results indicate that the RcCC2 gene is inducible and is involved in immune responses, suggesting RcCC2 has an important role in the early stage of viral and bacterial infections.

  17. Exchange of availability/performance data on base-load gas turbine and combined cycle plant

    Energy Technology Data Exchange (ETDEWEB)

    Jesuthasan, D.K.; Kaupang, B.M. (Tenaga Nasional Berhad (Malaysia))

    1992-09-01

    This paper describes the recommendations developed to facilitate the international exchange of availability performance data on base-load gas turbines and combined cycle plant. Standardized formats for the collection of plant availability statistics, recognizing the inherent characteristics of gas turbines in simple and combined cycle plants are presented. The formats also allow for a logical expansion of the data collection detail as that becomes desirable. To assist developing countries in particular, the approach includes basic formats for data collection needed for international reporting. In addition, the participating utilities will have a meaningful database for internal use. As experience is gained with this data colletion system, it is expected that additional detail may be accommodated to enable further in-depth performance analysis on the plant and on the utility level. 2 refs., 2 tabs., 11 apps.

  18. A bonding study of c-C5H8 adsorption on Pt(111)

    International Nuclear Information System (INIS)

    Simonetti, S.; Jasen, P.; Gonzalez, E.; Juan, A.; Brizuela, G.

    2006-01-01

    The chemisorption of cyclopentane (c-C 5 H 8 ) on Pt(111) has been studied using a qualitative band-structure calculations in the framework of tight-binding implementation with the YAeHMOP package. We modeled the metal surface by a two-dimensional slab of finite thickness with an overlayer of c-C 5 H 8 , in a (3x3) di-σ geometry. The c-C 5 H 8 molecule is attached to the surface with its C?C atoms bonded mainly with two Pt atoms while the opposite CH 2 bends towards the surface. The Pt?Pt bonds in the underlying surface and the C?C bonds of c-C 5 H 8 are weakened upon the chemisorption. A noticeable Pt-H and Pt-C interactions has been observed. We found that of Pt 5d z 2 band plays an important role in the bonding between c-C 5 H 8 and the surface, as do the Pt 6s and 6p z bands. The HOMO-LUMO bands of c-C 5 H 8 are very dispersed, indicative of a strong interaction with the metal surface

  19. Combined methodology of optimization and life cycle inventory for a biomass gasification based BCHP system

    International Nuclear Information System (INIS)

    Wang, Jiang-Jiang; Yang, Kun; Xu, Zi-Long; Fu, Chao; Li, Li; Zhou, Zun-Kai

    2014-01-01

    Biomass gasification based building cooling, heating, and power (BCHP) system is an effective distributed energy system to improve the utilization of biomass resources. This paper proposes a combined methodology of optimization method and life cycle inventory (LCI) for the biomass gasification based BCHP system. The life cycle models including biomass planting, biomass collection-storage-transportation, BCHP plant construction and operation, and BCHP plant demolition and recycle, are constructed to obtain economic cost, energy consumption and CO 2 emission in the whole service-life. Then, the optimization model for the biomass BCHP system including variables, objective function and solution method are presented. Finally, a biomass BCHP case in Harbin, China, is optimized under different optimization objectives, the life-cycle performances including cost, energy and CO 2 emission are obtained and the grey incidence approach is employed to evaluate their comprehensive performances of the biomass BCHP schemes. The results indicate that the life-cycle cost, energy efficiency and CO 2 emission of the biomass BCHP system are about 41.9 $ MWh −1 , 41% and 59.60 kg MWh −1 respectively. The optimized biomass BCHP configuration to minimize the life-cycle cost is the best scheme to achieve comprehensive benefit including cost, energy consumption, renewable energy ratio, steel consumption, and CO 2 emission. - Highlights: • Propose the combined method of optimization and LCI for biomass BCHP system. • Optimize the biomass BCHP system to minimize the life-cycle cost, energy and emission. • Obtain the optimized life-cycle cost, energy efficiency and CO 2 emission. • Select the best biomass BCHP scheme using grey incidence approach

  20. Exergoeconomic assessment and parametric study of a Gas Turbine-Modular Helium Reactor combined with two Organic Rankine Cycles

    International Nuclear Information System (INIS)

    Mohammadkhani, F.; Shokati, N.; Mahmoudi, S.M.S.; Yari, M.; Rosen, M.A.

    2014-01-01

    An exergoeconomic analysis is reported for a combined system with a net electrical output of 299 MW in which waste heat from a Gas Turbine-Modular Helium Reactor (GT-MHR) is utilized by two Organic Rankine Cycles (ORCs). A parametric study is also done to reveal the effects on the exergoeconomic performance of the combined system of such significant parameters as compressor pressure ratio, turbine inlet temperature, temperatures of evaporators, pinch point temperature difference in the evaporators and degree of superheat at the ORC (Organic Rankine Cycle) turbines inlet. Finally the combined cycle performance is optimized from the viewpoint of exergoeconomics. The results show that the precooler, the intercooler and the ORC condensers exhibit the worst exergoeconomic performance. For the overall system, the exergoeconomic factor, the capital cost rate and the exergy destruction cost rate are determined to be 37.95%, 6876 $/h and 11,242 $/h, respectively. Also, it is observed that the unit cost of electricity produced by the GT-MHR turbine increases with increasing GT-MHR turbine inlet temperature but decreases as the other above mentioned parameters increase. - Highlights: • An exergoeconomic analysis is performed for the GT-MHR/ORC (Organic Rankine Cycle) combined cycle. • The effects of decision parameters on the exergoeconomic performance are studied. • The highest exergy destructions occur in the precooler, intercooler and condenser. • Superheating the working fluid at the ORC turbine inlet is not necessary. • Thermodynamic and exergoeconomic optimal conditions differ from each other

  1. Combined cycle versus one thousand diesel power plants: pollutant emissions, ecological efficiency and economic analysis

    International Nuclear Information System (INIS)

    Silveira, Jose Luz; de Carvalho, Joao Andrade; de Castro Villela, Iraides Aparecida

    2007-01-01

    The increase in the use of natural gas in Brazil has stimulated public and private sectors to analyse the possibility of using combined cycle systems for generation of electrical energy. Gas turbine combined cycle power plants are becoming increasingly common due to their high efficiency, short lead times, and ability to meet environmental standards. Power is produced in a generator linked directly to the gas turbine. The gas turbine exhaust gases are sent to a heat recovery steam generator to produce superheated steam that can be used in a steam turbine to produce additional power. In this paper a comparative study between a 1000 MW combined cycle power plant and 1000kW diesel power plant is presented. In first step, the energetic situation in Brazil, the needs of the electric sector modification and the needs of demand management and integrated means planning are clarified. In another step the characteristics of large and small thermoelectric power plants that use natural gas and diesel fuel, respectively, are presented. The ecological efficiency levels of each type of power plant is considered in the discussion, presenting the emissions of particulate material, sulphur dioxide (SO 2 ), carbon dioxide (CO 2 ) and nitrogen oxides (NO x ). (author)

  2. Improvement of performance operation and cycle efficiency of Al Anbar combined power plant

    International Nuclear Information System (INIS)

    Jabbar, Mohammed Q.

    2014-01-01

    The present work will be focusing on available solution which can serve to increase total efficiency of Al Anbar combined cycle power plant - CCPP, and thus to improve the operation performance as much as possible in order to decrease hydrocarbon, CO2, NOx emissions to environment.The simulation and calculations were performed by program software cycle-tempo software. The results were compared with basic design of Alanbar power plant after making modernization with solar tower receiver system-STRS, which represented a heat source in preheat process for a compressor air. Key Words: CCPP, STRS, Solar potential energy, fuel consumption, hydrocarbon emission

  3. Performance comparison of two low-CO2 emission solar/methanol hybrid combined cycle power systems

    International Nuclear Information System (INIS)

    Li, Yuanyuan; Zhang, Na; Lior, Noam

    2015-01-01

    Highlights: • Two novel solar hybrid combined cycle systems have been proposed and analyzed. • The power systems integrate solar-driven thermo-chemical conversion and CO 2 capture. • Exergy efficiency of about 55% and specific CO 2 emissions of 34 g/kW h are predicted. • Systems CO 2 emissions are 36.8% lower compared to a combined cycle with CO 2 capture. • The fossil fuel demand is ∼30% lower with a solar share of ∼20%. - Abstract: Two novel hybrid combined cycle power systems that use solar heat and methanol, and integrate CO 2 capture, are proposed and analyzed, one based on solar-driven methanol decomposition and the other on solar-driven methanol reforming. The high methanol conversion rates at relatively low temperatures offer the advantage of using the solar heat at only 200–300 °C to drive the syngas production by endothermic methanol conversions and its conversion to chemical energy. Pre-combustion decarbonization is employed to produce CO 2 -free fuel from the fully converted syngas, which is then burned to produce heat at the high temperature for power generation in the proposed advanced combined cycle systems. To improve efficiency, the systems’ configurations were based on the principle of cascade use of multiple heat sources of different temperatures. The thermodynamic performance of the hybrid power systems at its design point is simulated and evaluated. The results show that the hybrid systems can attain an exergy efficiency of about 55%, and specific CO 2 emissions as low as 34 g/kW h. Compared to a gas/steam combined cycle with flue gas CO 2 capture, the proposed solar-assisted system CO 2 emissions are 36.8% lower, and a fossil fuel saving ratio of ∼30% is achievable with a solar thermal share of ∼20%. The system integration predicts high efficiency conversion of solar heat and low-energy-penalty CO 2 capture, with the additional advantage that solar heat is at relatively low temperature where its collection is cheaper and

  4. Externally-fired combined cycle: An effective coal fueled technology for repowering and new generation

    Energy Technology Data Exchange (ETDEWEB)

    Stoddard, L.E.; Bary, M.R. [Black and Veatch, Kansas City, MO (United States); Gray, K.M. [Pennsylvania Electric Co., Johnstown, PA (United States); LaHaye, P.G. [Hague International, South Portland, ME (United States)

    1995-06-01

    The Externally-Fired Combined Cycle (EFCC) is an attractive emerging technology for powering high efficiency combined gas and steam turbine cycles with coal or other ash bearing fuels. In the EFCC, the heat input to a gas turbine is supplied indirectly through a ceramic air heater. The air heater, along with an atmospheric coal combustor and ancillary equipment, replaces the conventional gas turbine combustor. A steam generator located downstream from the ceramic air heater and steam turbine cycle, along with an exhaust cleanup system, completes the combined cycle. A key element of the EFCC Development Program, the 25 MMBtu/h heat-input Kennebunk Test Facility (KTF), has recently begun operation. The KTF has been operating with natural gas and will begin operating with coal in early 1995. The US Department of Energy selected an EFCC repowering of the Pennsylvania Electric Company`s Warren Station for funding under the Clean Coal Technology Program Round V. The project focuses on repowering an existing 48 MW (gross) steam turbine with an EFCC power island incorporating a 30 MW gas turbine, for a gross power output of 78 MW and a net output of 72 MW. The net plant heat rate will be decreased by approximately 30% to below 9,700 Btu/kWh. Use of a dry scrubber and fabric filter will reduce sulfur dioxide (SO{sub 2}) and particulate emissions to levels under those required by the Clean Air Act Amendments (CAAA) of 1990. Nitrogen oxides (NO{sub x}) emissions are controlled by the use of staged combustion. The demonstration project is currently in the engineering phase, with startup scheduled for 1997. This paper discusses the background of the EFCC, the KTF, the Warren Station EFCC Clean Coal Technology Demonstration Project, the commercial plant concept, and the market potential for the EFCC.

  5. Integrated gasification combined-cycle research development and demonstration activities in the US

    Energy Technology Data Exchange (ETDEWEB)

    Ness, H.M.; Brdar, R.D.

    1996-09-01

    The United States Department of Energy (DOE)`s Office of Fossil Energy, Morgantown Energy Technology Center, is managing a research development and demonstration (RD&D) program that supports the commercialization of integrated gasification combined-cycle (IGCC) advanced power systems. This overview briefly describes the supporting RD&D activities and the IGCC projects selected for demonstration in the Clean Coal Technology (CCT) Program.

  6. Combined cycle solar central receiver hybrid power system study. Final technical report. Volume II

    Energy Technology Data Exchange (ETDEWEB)

    None

    1979-11-01

    This study develops the conceptual design for a commercial-scale (nominal 100 MWe) central receiver solar/fossil fuel hybrid power system with combined cycle energy conversion. A near-term, metallic heat pipe receiver and an advanced ceramic tube receiver hybrid system are defined through parametric and market potential analyses. Comparative evaluations of the cost of power generation, the fuel displacement potential, and the technological readiness of these two systems indicate that the near-term hybrid system has better potential for commercialization by 1990. Based on the assessment of the conceptual design, major cost and performance improvements are projected for the near-term system. Constraints preventing wide-spread use were not identified. Energy storage is not required for this system and analyses show no economic advantages with energy storage provisions. It is concluded that the solar hybrid system is a cost effective alternative to conventional gas turbines and combined cycle generating plants, and has potential for intermediate-load market penetration at 15% annual fuel escalation rate. Due to their flexibility, simple solar/nonsolar interfacing, and short startup cycles, these hybrid plants have significant operating advantages. Utility company comments suggest that hybrid power systems will precede stand-alone solar plants.

  7. Integrated gasification gas combined cycle plant with membrane reactors: Technological and economical analysis

    International Nuclear Information System (INIS)

    Amelio, Mario; Morrone, Pietropaolo; Gallucci, Fausto; Basile, Angelo

    2007-01-01

    In the present work, the capture and storage of carbon dioxide from the fossil fuel power plant have been considered. The main objective was to analyze the thermodynamic performances and the technological aspects of two integrated gasification gas combined cycle plants (IGCC), as well as to give a forecast of the investment costs for the plants and the resulting energy consumptions. The first plant considered is an IGCC* plant (integrated gasification gas combined cycle plant with traditional shift reactors) characterized by the traditional water gas shift reactors and a CO 2 physical adsorption system followed by the power section. The second one is an IGCC M plant (integrated gasification gas combined cycle plant with membrane reactor) where the coal thermal input is the same as the first one, but the traditional shift reactors and the physical adsorption unit are replaced by catalytic palladium membrane reactors (CMR). In the present work, a mono-dimensional computational model of the membrane reactor was proposed to simulate and evaluate the capability of the IGCC M plant to capture carbon dioxide. The energetic performances, efficiency and net power of the IGCC* and IGCC M plants were, thus, compared, assuming as standard a traditional IGCC plant without carbon dioxide capture. The economical aspects of the three plants were compared through an economical analysis. Since the IGCC* and IGCC M plants have additional costs related to the capture and disposal of the carbon dioxide, a Carbon Tax (adopted in some countries like Sweden) proportional to the number of kilograms of carbon dioxide released in the environment was assumed. According to the economical analysis, the IGCC M plant proved to be more convenient than the IGCC* one

  8. Radiological diagnosis and intervention of cholangiocarcinomas (CC); Radiologische Diagnostik und Intervention von Cholangiokarzinomen (CC)

    Energy Technology Data Exchange (ETDEWEB)

    Vogl, T.J.; Zangos, S.; Eichler, K.; Gruber-Rouh, T.; Hammerstingl, R.M.; Weisser, P. [Frankfurt Univ. (Germany). Inst. fuer Diagnostische und Interventionelle Radiologie; Trojan, J. [Frankfurt Univ. (Germany). Medizinische Klinik I: Gastroenterologie, Endokrinologie, Pneumologie/Allergologie

    2012-10-15

    To present current data on diagnosis, indication and different therapy options in patients with cholangiocarcinoma (CC) based on an analysis of the current literature and clinical experience. The diagnostic routine includes laboratory investigations with parameters of cholestasis and also serum tumor markers CA19 - 9 and CEA. After ultrasound for clarifying a tumor and/or dilated bile ducts, contrast-enhanced magnetic resonance imaging (MRI) should be performed with magnetic resonance cholangiography (MRCP). The accuracy (positive predictive value) for diagnosing a CC is 37 - 84 % (depending on the location) for ultrasound, 79 - 94 % for computed tomography (CT), and 95 % for MRI and MRCP. An endoscopic retrograde cholangiography (ERCP) can then be planned, especially if biliary drainage or cytological or histological specimen sampling is intended. A curative approach can be achieved by surgical resection, rarely by liver transplantation. However, many patients are not eligible for surgery. In addition to systemic chemotherapy, locoregional therapies such as transarterial chemoembolization (TACE), hepatic arterial infusion (HAI) - also known as chemoperfusion -, drug eluting beads-therapy (DEB) as well as thermoablative procedures, such as laser-induced thermotherapy (LITT), microwave ablation (MWA) and radiofrequency ablation (RFA) can be provided with a palliative intention.

  9. Exergy analysis and optimisation of a marine molten carbonate fuel cell system in simple and combined cycle configuration

    International Nuclear Information System (INIS)

    Dimopoulos, George G.; Stefanatos, Iason C.; Kakalis, Nikolaos M.P.

    2016-01-01

    Highlights: • Process modelling and optimisation of an integrated marine MCFC system. • Component-level and spatially distributed exergy analysis and balances. • Optimal simple cycle MCFC system with 45.5% overall exergy efficiency. • Optimal combined cycle MCFC system with 60% overall exergy efficiency. • Combined cycle MCFC system yields 30% CO_2 relative emissions reduction. - Abstract: In this paper we present the exergy analysis and design optimisation of an integrated molten carbonate fuel cell (MCFC) system for marine applications, considering waste heat recovery options for additional power production. High temperature fuel cells are attractive solutions for marine energy systems, as they can significantly reduce gaseous emissions, increase efficiency and facilitate the introduction of more environmentally-friendly fuels, like LNG and biofuels. We consider an already installed MCFC system onboard a sea-going vessel, which has many tightly integrated sub-systems and components: fuel delivery and pre-reforming, internal reforming sections, electrochemical conversion, catalytic burner, air supply and high temperature exhaust gas. The high temperature exhaust gasses offer significant potential for heat recovery that can be directed into both covering the system’s auxiliary heat requirements and power production. Therefore, an integrated systems approach is employed to accurately identify the true sources of losses in the various components and to optimise the overall system with respect to its energy efficiency, taking into account the various trade-offs and subject to several constraints. Here, we present a four-step approach: a. dynamic process models development of simple and combined-cycle MCFC system; b. MCFC components and system models calibration via onboard MCFC measurements; c. exergy analysis, and d. optimisation of the simple and combined-cycle systems with respect to their exergetic performance. Our methodology is based on the

  10. Energy Materials Coordinating Committee (EMaCC): Fiscal year 1996. Annual technical report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-08-01

    The DOE Energy Materials Coordinating Committee (EMaCC) serves primarily to enhance coordination among the Department`s materials programs and to further effective use of materials expertise within the Department. These functions are accomplished through the exchange of budgetary and planning information among program managers and through technical meetings/workshops on selected topics involving both DOE and major contractors. In addition, EMaCC assists in obtaining materials-related inputs for both intra- and interagency compilations. The EMaCC reports to the Director of the Office of Energy Research in his or her capacity as overseer of the technical programs of the Department. This annual technical report is mandated by the EMaCC terms of reference. This report summarizes EMaCC activities for FY 1996 and describes the materials research programs of various offices and divisions within the Department.

  11. Energy Materials Coordinating Committee (EMaCC): Fiscal year 1996. Annual technical report

    International Nuclear Information System (INIS)

    1997-08-01

    The DOE Energy Materials Coordinating Committee (EMaCC) serves primarily to enhance coordination among the Department's materials programs and to further effective use of materials expertise within the Department. These functions are accomplished through the exchange of budgetary and planning information among program managers and through technical meetings/workshops on selected topics involving both DOE and major contractors. In addition, EMaCC assists in obtaining materials-related inputs for both intra- and interagency compilations. The EMaCC reports to the Director of the Office of Energy Research in his or her capacity as overseer of the technical programs of the Department. This annual technical report is mandated by the EMaCC terms of reference. This report summarizes EMaCC activities for FY 1996 and describes the materials research programs of various offices and divisions within the Department

  12. Building carbon-carbon bonds using a biocatalytic methanol condensation cycle.

    Science.gov (United States)

    Bogorad, Igor W; Chen, Chang-Ting; Theisen, Matthew K; Wu, Tung-Yun; Schlenz, Alicia R; Lam, Albert T; Liao, James C

    2014-11-11

    Methanol is an important intermediate in the utilization of natural gas for synthesizing other feedstock chemicals. Typically, chemical approaches for building C-C bonds from methanol require high temperature and pressure. Biological conversion of methanol to longer carbon chain compounds is feasible; however, the natural biological pathways for methanol utilization involve carbon dioxide loss or ATP expenditure. Here we demonstrated a biocatalytic pathway, termed the methanol condensation cycle (MCC), by combining the nonoxidative glycolysis with the ribulose monophosphate pathway to convert methanol to higher-chain alcohols or other acetyl-CoA derivatives using enzymatic reactions in a carbon-conserved and ATP-independent system. We investigated the robustness of MCC and identified operational regions. We confirmed that the pathway forms a catalytic cycle through (13)C-carbon labeling. With a cell-free system, we demonstrated the conversion of methanol to ethanol or n-butanol. The high carbon efficiency and low operating temperature are attractive for transforming natural gas-derived methanol to longer-chain liquid fuels and other chemical derivatives.

  13. Comparison of The Effectiveness of Clomiphene Citrate versus Letrozole in Mild IVF in Poor Prognosis Subfertile Women with Failed IVF Cycles

    Directory of Open Access Journals (Sweden)

    Mesut Oktem

    2015-10-01

    Full Text Available Background: Our objective was to evaluate the effectiveness of clomiphene citrate (CC vs. letrozole (L plus human menopausal gonadotropin (hMG in gonadotropin releasing hormone (GnRH antagonist protocol in poor prognosis women with previous failed ovarian stimulation undergoing intracytoplasmic sperm injection (ICSI. Materials and Methods: This retrospective cohort study included cycles with CC and L plus hMG/GnRH antagonist protocols of 32 poor responders who had failed to have ideal follicles to be retrieved during oocyte pick-up (OPU or embryo transfer (ET at least for 2 previous in vitro fertilization (IVF cycles with microdose flare protocol or GnRH antagonist protocol from January 2006 to December 2009. Main outcome measures were implantation, clinical pregnancy and live birth rates per cycle. Duration of stimulation, mean gonadotropin dose used, endometrial thickness, number of mature follicles, serum estradiol (E2 and progesterone (P levels on the day of human chorionic gonadotropin (hCG administration, number of retrieved oocytes and fertilization rates were also evaluated. Results: A total number of 42 cycles of 32 severe poor responders were evaluated. Total gonadotropin consumption was significantly lower (1491 ± 873 vs. 2808 ± 1581 IU, P=0.005 and mean E2 level on the day of hCG injection were significantly higher in CC group than L group (443.3 ± 255.2 vs. 255.4 ± 285.2 pg/mL, P=0.03. ET, overall pregnancy and live birth rates per cycle were significantly higher in CC than L protocol (27.2 vs. 15%, 13.6 vs. 0% and 4.5 vs. 0%, respectively, P<0.05. Conclusion: Severe poor responders who had previously failed to respond to microdose or GnRH antagonist protocols may benefit from CC plus hMG/GnRH antagonist protocol despite high cancellation rate.

  14. Thermodynamic analysis and conceptual design for partial coal gasification air preheating coal-fired combined cycle

    Science.gov (United States)

    Xu, Yue; Wu, Yining; Deng, Shimin; Wei, Shirang

    2004-02-01

    The partial coal gasification air pre-heating coal-fired combined cycle (PGACC) is a cleaning coal power system, which integrates the coal gasification technology, circulating fluidized bed technology, and combined cycle technology. It has high efficiency and simple construction, and is a new selection of the cleaning coal power systems. A thermodynamic analysis of the PGACC is carried out. The effects of coal gasifying rate, pre-heating air temperature, and coal gas temperature on the performances of the power system are studied. In order to repower the power plant rated 100 MW by using the PGACC, a conceptual design is suggested. The computational results show that the PGACC is feasible for modernizing the old steam power plants and building the new cleaning power plants.

  15. Combined cycles, impacts of technological requirements; Ciclos combinados, impactos de requerimientos tecnologicos

    Energy Technology Data Exchange (ETDEWEB)

    Gonzalez Santalo, Jose Miguel [Instituto de Investigaciones Electricas, Temixco, Morelos (Mexico)

    1999-07-01

    The fundamental growth of the Mexican electrical sector for the next ten years is planned on base of the installation of 20 thousand Mw plants of combined cycle. This article presents an analysis of the impact of these power stations finding out that the power stations of combined cycle are at the moment cheaper - from 600 to 700 dollars by installed kW- than the alternative coal options or fuel oil, that are in the range of 900 to 1200 dollars per kW, in addition to which the time required for their construction is shorter. [Spanish] El crecimiento fundamental del sector electrico mexicano para los proximos diez anos esta planeado con base en la instalacion de 20 mil Mw de plantas de ciclo combinado. Este articulo presenta un analisis del impacto de dichas centrales encontrando que las centrales de ciclo combinado actualmente resultan mas baratas - de 600 a 700 dolares por kW instalado - que las opciones alternativas de carbon o combustoleo que estan en el rango de 900 a 1200 dolares por kW, ademas de que los tiempos requeridos para su construccion son menores.

  16. Thermodynamic analysis on theoretical models of cycle combined heat exchange process: The reversible heat exchange process

    International Nuclear Information System (INIS)

    Zhang, Chenghu; Li, Yaping

    2017-01-01

    Concept of reversible heat exchange process as the theoretical model of the cycle combined heat exchanger could be useful to determine thermodynamics characteristics and the limitation values in the isolated heat exchange system. In this study, the classification of the reversible heat exchange processes is presented, and with the numerical method, medium temperature variation tendency and the useful work production and usage in the whole process are investigated by the construction and solution of the mathematical descriptions. Various values of medium inlet temperatures and heat capacity ratio are considered to analyze the effects of process parameters on the outlet temperature lift/drop. The maximum process work transferred from the Carnot cycle region to the reverse cycle region is also researched. Moreover, influence of the separating point between different sub-processes on temperature variation profile and the process work production are analyzed. In addition, the heat-exchange-enhancement-factor is defined to study the enhancement effect of the application of the idealized process in the isolated heat exchange system, and the variation degree of this factor with process parameters change is obtained. The research results of this paper can be a theoretical guidance to construct the cycle combined heat exchange process in the practical system. - Highlights: • A theoretical model of Cycle combined heat exchange process is proposed. • The classification of reversible heat exchange process are presented. • Effects of Inlet temperatures and heat capacity ratio on process are analyzed. • Process work transmission through the whole process is studied. • Heat-exchange-enhancement-factor can be a criteria to express the application effect of the idealized process.

  17. Metal-organic cooperative catalysis in C-H and C-C bond activation and its concurrent recovery.

    Science.gov (United States)

    Park, Young Jun; Park, Jung-Woo; Jun, Chul-Ho

    2008-02-01

    components using a hydrogen-bonded self-assembled system as a catalyst support. This catalyst-recovery system provides a homogeneous phase at high temperature during the reaction and a heterogeneous phase at room temperature after the reaction. The product could be separated conveniently from the self-assembly support system by decanting the upper layer. The immobilized catalysts of both 2-aminopyridine and rhodium metal species sustained high catalytic activity for up to the eight catalytic reactions. In conclusion, the successful incorporation of an organocatalytic cycle into a transition metal catalyzed reaction led us to find MOCC for C-H and C-C bond activation. In addition, the hydrogen-bonded self-assembled support has been developed for an efficient and effective recovery system of homogeneous catalysts and could be successful in immobilizing both metal and organic catalysts.

  18. Highlights from a Mach 4 Experimental Demonstration of Inlet Mode Transition for Turbine-Based Combined Cycle Hypersonic Propulsion

    Science.gov (United States)

    Foster, Lancert E.; Saunders, John D., Jr.; Sanders, Bobby W.; Weir, Lois J.

    2012-01-01

    NASA is focused on technologies for combined cycle, air-breathing propulsion systems to enable reusable launch systems for access to space. Turbine Based Combined Cycle (TBCC) propulsion systems offer specific impulse (Isp) improvements over rocket-based propulsion systems in the subsonic takeoff and return mission segments along with improved safety. Among the most critical TBCC enabling technologies are: 1) mode transition from the low speed propulsion system to the high speed propulsion system, 2) high Mach turbine engine development and 3) innovative turbine based combined cycle integration. To address these challenges, NASA initiated an experimental mode transition task including analytical methods to assess the state-of-the-art of propulsion system performance and design codes. One effort has been the Combined-Cycle Engine Large Scale Inlet Mode Transition Experiment (CCE-LIMX) which is a fully integrated TBCC propulsion system with flowpath sizing consistent with previous NASA and DoD proposed Hypersonic experimental flight test plans. This experiment was tested in the NASA GRC 10 by 10-Foot Supersonic Wind Tunnel (SWT) Facility. The goal of this activity is to address key hypersonic combined-cycle engine issues including: (1) dual integrated inlet operability and performance issues-unstart constraints, distortion constraints, bleed requirements, and controls, (2) mode-transition sequence elements caused by switching between the turbine and the ramjet/scramjet flowpaths (imposed variable geometry requirements), and (3) turbine engine transients (and associated time scales) during transition. Testing of the initial inlet and dynamic characterization phases were completed and smooth mode transition was demonstrated. A database focused on a Mach 4 transition speed with limited off-design elements was developed and will serve to guide future TBCC system studies and to validate higher level analyses.

  19. Exergetic and economic evaluation of the effect of HRSG configurations on the performance of combined cycle power plants

    International Nuclear Information System (INIS)

    Tajik Mansouri, Mohammad; Ahmadi, Pouria; Ganjeh Kaviri, Abdolsaeid; Jaafar, Mohammad Nazri Mohd

    2012-01-01

    Highlights: ►To conduct the comprehensive exergy and economic analysis for advanced combined cycle power plant. ►To study three different HRSG configurations, dual and triple pressure HRSG, based on thermodynamic relations. ►To have a better performance assessment of the system studied using exergy and economic criteria. - Abstract: In the present research study, the effect of HRSG pressure levels on exergy efficiency of combined cycle power plants is investigated. Hence, three types of gas turbine combined cycles, with the same gas turbine as a topping cycle are evaluated. A double pressure, and two triple pressure HRSGs (with and without reheat) are modeled. The results show how an increase in the number of pressure levels of the HRSG affect the exergy losses due to heat transfer in the HRSG and the exhaust of flue gas to the stack. Moreover, the results show that an increase in the number of pressure levels affects the exergy destruction rate in HRSG, and as a result, it causes a tangible increase in exergy efficiency of the whole cycle. The results from thermodynamic analysis show that the losses due to heat transfer in the HRSG and the exhaust of flue gas to the stack in a triple pressure reheat combined cycle are less than the other cases. From the economic analysis, it is found that increasing the number of pressure levels of steam generation leads to an increase for the total and specific investment cost of the plant for about 6% and 4% respectively. The net present value (NPV) of the plant increases for about 7% for triple pressure reheat compared to with the double pressure CCPP. Therefore, the results of economic analysis show that it is economically justifiable to increase the number of pressure levels of steam generation in HRSG.

  20. Evaluation of a combined cycle based on an HCCI (Homogenous Charge Compression Ignition) engine heat recovery employing two organic Rankine cycles

    International Nuclear Information System (INIS)

    Khaljani, M.; Saray, R. Khoshbakhti; Bahlouli, K.

    2016-01-01

    In this work, a combined power cycle which includes a HCCI (Homogenous Charge Compression Ignition) engine and two ORCs (Organic Rankine Cycles) is introduced. In the proposed cycle, the waste heats from the engine cooling water and exhaust gases are utilized to drive the ORCs. A parametric study is conducted to show the effects of decision parameters on the performance and on the total cost rate of cycle. Results of the parametric study reveal that increasing the pinch point temperature difference of evaporator and temperature of the condenser leads to reduction in both exergy efficiency and total cost rate of the bottoming cycle. There is a specific evaporator temperature where exergy efficiency is improved, but the total cost rate of the bottoming cycle is maximized. Also, a multi-objective optimization strategy is performed to achieve the best system design parameters from both thermodynamic and economic aspects. The exergy efficiency and the total cost rate of the system have been considered as objective functions. Optimization results indicate that the exergy efficiency of the cycle increases from 44.96% for the base case to 46.02%. Also, approximately1.3% reduction in the cost criteria is achieved. Results of the multi-objective optimization justify the results obtained through the parametric study and demonstrate that the design parameters of both ORCs have conflict effect on the objective functions. - Highlights: • Two Organic Rankine bottoming cycles are coupled with an HCCI Engine. • Exergetic and Exergo-economic analysis of the bottoming cycle are reported. • The system is optimized using multi-objective genetic algorithm. • Objective functions are exergy efficiency and total cost rate of the system. • The exergy efficiency of the cycle increases from 44.96% to 46.02%.

  1. {sup 68}Ga-PSMA-HBED-CC PET imaging in breast carcinoma patients

    Energy Technology Data Exchange (ETDEWEB)

    Sathekge, Mike; Lengana, Thabo; Modiselle, Moshe; Vorster, Mariza; Zeevaart, JanRijn; Ebenhan, Thomas [University of Pretoria and Steve Biko Academic Hospital, Department of Nuclear Medicine, Pretoria (South Africa); Maes, Alex [University of Pretoria and Steve Biko Academic Hospital, Department of Nuclear Medicine, Pretoria (South Africa); AZ Groeninge, Department of Nuclear Medicine, Kortrijk (Belgium); Wiele, Christophe van de [University of Pretoria and Steve Biko Academic Hospital, Department of Nuclear Medicine, Pretoria (South Africa); University Ghent, Department of Radiology and Nuclear Medicine, Ghent (Belgium)

    2017-04-15

    To report on imaging findings using {sup 68}Ga-PSMA-HBED-CC PET in a series of 19 breast carcinoma patients. {sup 68}Ga-PSMA-HBED-CC PET imaging results obtained were compared to routinely performed staging examinations and analyzed as to lesion location and progesterone receptor status. Out of 81 tumor lesions identified, 84% were identified on {sup 68}Ga-PSMA-HBED-CC PET. {sup 68}Ga-PSMA-HBED-CC SUVmean values of distant metastases proved significantly higher (mean, 6.86, SD, 5.68) when compared to those of primary or local recurrences (mean, 2.45, SD, 2.55, p = 0.04) or involved lymph nodes (mean, 3.18, SD, 1.79, p = 0.011). SUVmean values of progesterone receptor-positive lesions proved not significantly different from progesterone receptor-negative lesions. SUV values derived from FDG PET/CT, available in seven patients, and {sup 68}Ga-PSMA-HBED-CC PET/CT imaging proved weakly correlated (r = 0.407, p = 0.015). {sup 68}Ga-PSMA-HBED-CC PET/CT imaging in breast carcinoma confirms the reported considerable variation of PSMA expression on human solid tumors using immunohistochemistry. (orig.)

  2. Combined Cycle Power Generation Employing Pressure Gain Combustion

    Energy Technology Data Exchange (ETDEWEB)

    Holley, Adam [United Technologies Corporation, East Hartford, CT (United States). Research Center

    2017-05-15

    The Phase I program assessed the potential benefit of applying pressure gain combustion (PGC) technology to a natural gas combined cycle power plant. A conceptual design of the PGC integrated gas turbine was generated which was simulated in a detailed system modeling tool. The PGC integrated system was 1.93% more efficient, produced 3.09% more power, and reduced COE by 0.58%. Since the PGC system used had the same fuel flow rate as the baseline system, it also reduced CO2 emissions by 3.09%. The PGC system did produce more NOx than standard systems, but even with the performanceand cost penalties associated with the cleanup system it is better in every measure. This technology benefits all of DOE’s stated program goals to improve plant efficiency, reduce CO2 production, and reduce COE.

  3. Sadhana | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Heat recovery steam generator (HRSG) plays a key role on performance of combined cycle (CC). In this work, attention was focused on a dual pressure reheat (DPRH) HRSG to maximize the heat recovery and hence performance of CC. Deaerator, an essential open feed water heater in steam bottoming cycle was located ...

  4. High-Efficiency Small-Scale Combined Heat and Power Organic Binary Rankine Cycles

    Directory of Open Access Journals (Sweden)

    Costante Mario Invernizzi

    2018-04-01

    Full Text Available Small-CHP (Combined Heat and Power systems are generally considered a valuable technological option to the conventional boilers, in a technology developed context. If small-CHP systems are associated with the use of renewable energies (biomass, for example they could play an important role in distributed generation even in developing countries or, in any case, where there are no extensive electricity networks. Traditionally the considered heat engines for micro- or mini-CHP are: the gas engine, the gas turbine (with internal combustion, the steam engine, engine working according to the Stirling and to the Rankine cycles, the last with organic fluids. In principle, also fuel cells could be used. In this paper, we focus on small size Rankine cycles (10–15 k W with organic working fluids. The assumed heat source is hot combustion gases at high temperature (900–950 ∘ C and we assume to use only single stages axial turbines. The need to work at high temperatures, limits the choice of the right organic working fluids. The calculation results show the limitation in the performances of simple cycles and suggest the opportunity to resort to complex (binary cycle configurations to achieve high net conversion efficiencies (15–16%.

  5. Observation of the Doubly Charmed Baryon Ξ_{cc}^{++}.

    Science.gov (United States)

    Aaij, R; Adeva, B; Adinolfi, M; Ajaltouni, Z; Akar, S; Albrecht, J; Alessio, F; Alexander, M; Alfonso Albero, A; Ali, S; Alkhazov, G; Alvarez Cartelle, P; Alves, A A; Amato, S; Amerio, S; Amhis, Y; An, L; Anderlini, L; Andreassi, G; Andreotti, M; Andrews, J E; Appleby, R B; Archilli, F; d'Argent, P; Arnau Romeu, J; Artamonov, A; Artuso, M; Aslanides, E; Auriemma, G; Baalouch, M; Babuschkin, I; Bachmann, S; Back, J J; Badalov, A; Baesso, C; Baker, S; Balagura, V; Baldini, W; Baranov, A; Barlow, R J; Barschel, C; Barsuk, S; Barter, W; Baryshnikov, F; Batozskaya, V; Battista, V; Bay, A; Beaucourt, L; Beddow, J; Bedeschi, F; Bediaga, I; Beiter, A; Bel, L J; Beliy, N; Bellee, V; Belloli, N; Belous, K; Belyaev, I; Ben-Haim, E; Bencivenni, G; Benson, S; Beranek, S; Berezhnoy, A; Bernet, R; Berninghoff, D; Bertholet, E; Bertolin, A; Betancourt, C; Betti, F; Bettler, M-O; van Beuzekom, M; Bezshyiko, Ia; Bifani, S; Billoir, P; Birnkraut, A; Bitadze, A; Bizzeti, A; Bjoern, M B; Blake, T; Blanc, F; Blouw, J; Blusk, S; Bocci, V; Boettcher, T; Bondar, A; Bondar, N; Bonivento, W; Bordyuzhin, I; Borgheresi, A; Borghi, S; Borisyak, M; Borsato, M; Borysova, M; Bossu, F; Boubdir, M; Bowcock, T J V; Bowen, E; Bozzi, C; Braun, S; Britton, T; Brodzicka, J; Brundu, D; Buchanan, E; Burr, C; Bursche, A; Buytaert, J; Byczynski, W; Cadeddu, S; Cai, H; Calabrese, R; Calladine, R; Calvi, M; Calvo Gomez, M; Camboni, A; Campana, P; Campora Perez, D H; Capriotti, L; Carbone, A; Carboni, G; Cardinale, R; Cardini, A; Carniti, P; Carson, L; Carvalho Akiba, K; Casse, G; Cassina, L; Castillo Garcia, L; Cattaneo, M; Cavallero, G; Cenci, R; Chamont, D; Charles, M; Charpentier, Ph; Chatzikonstantinidis, G; Chefdeville, M; Chen, S; Cheung, S F; Chitic, S-G; Chobanova, V; Chrzaszcz, M; Chubykin, A; Ciambrone, P; Cid Vidal, X; Ciezarek, G; Clarke, P E L; Clemencic, M; Cliff, H V; Closier, J; Cogan, J; Cogneras, E; Cogoni, V; Cojocariu, L; Collins, P; Colombo, T; Comerma-Montells, A; Contu, A; Cook, A; Coombs, G; Coquereau, S; Corti, G; Corvo, M; Costa Sobral, C M; Couturier, B; Cowan, G A; Craik, D C; Crocombe, A; Cruz Torres, M; Currie, R; D'Ambrosio, C; Da Cunha Marinho, F; Dall'Occo, E; Dalseno, J; Davis, A; De Aguiar Francisco, O; De Capua, S; De Cian, M; De Miranda, J M; De Paula, L; De Serio, M; De Simone, P; Dean, C T; Decamp, D; Del Buono, L; Dembinski, H-P; Demmer, M; Dendek, A; Derkach, D; Deschamps, O; Dettori, F; Dey, B; Di Canto, A; Di Nezza, P; Dijkstra, H; Dordei, F; Dorigo, M; Dosil Suárez, A; Douglas, L; Dovbnya, A; Dreimanis, K; Dufour, L; Dujany, G; Durante, P; Dzhelyadin, R; Dziewiecki, M; Dziurda, A; Dzyuba, A; Easo, S; Ebert, M; Egede, U; Egorychev, V; Eidelman, S; Eisenhardt, S; Eitschberger, U; Ekelhof, R; Eklund, L; Ely, S; Esen, S; Evans, H M; Evans, T; Falabella, A; Farley, N; Farry, S; Fay, R; Fazzini, D; Federici, L; Ferguson, D; Fernandez, G; Fernandez Declara, P; Fernandez Prieto, A; Ferrari, F; Ferreira Rodrigues, F; Ferro-Luzzi, M; Filippov, S; Fini, R A; Fiore, M; Fiorini, M; Firlej, M; Fitzpatrick, C; Fiutowski, T; Fleuret, F; Fohl, K; Fontana, M; Fontanelli, F; Forshaw, D C; Forty, R; Franco Lima, V; Frank, M; Frei, C; Fu, J; Funk, W; Furfaro, E; Färber, C; Gabriel, E; Gallas Torreira, A; Galli, D; Gallorini, S; Gambetta, S; Gandelman, M; Gandini, P; Gao, Y; Garcia Martin, L M; García Pardiñas, J; Garra Tico, J; Garrido, L; Garsed, P J; Gascon, D; Gaspar, C; Gavardi, L; Gazzoni, G; Gerick, D; Gersabeck, E; Gersabeck, M; Gershon, T; Ghez, Ph; Gianì, S; Gibson, V; Girard, O G; Giubega, L; Gizdov, K; Gligorov, V V; Golubkov, D; Golutvin, A; Gomes, A; Gorelov, I V; Gotti, C; Govorkova, E; Grabowski, J P; Graciani Diaz, R; Granado Cardoso, L A; Graugés, E; Graverini, E; Graziani, G; Grecu, A; Greim, R; Griffith, P; Grillo, L; Gruber, L; Gruberg Cazon, B R; Grünberg, O; Gushchin, E; Guz, Yu; Gys, T; Göbel, C; Hadavizadeh, T; Hadjivasiliou, C; Haefeli, G; Haen, C; Haines, S C; Hamilton, B; Han, X; Hancock, T; Hansmann-Menzemer, S; Harnew, N; Harnew, S T; Harrison, J; Hasse, C; Hatch, M; He, J; Hecker, M; Heinicke, K; Heister, A; Hennessy, K; Henrard, P; Henry, L; van Herwijnen, E; Heß, M; Hicheur, A; Hill, D; Hombach, C; Hopchev, P H; Huard, Z-C; Hulsbergen, W; Humair, T; Hushchyn, M; Hutchcroft, D; Ibis, P; Idzik, M; Ilten, P; Jacobsson, R; Jalocha, J; Jans, E; Jawahery, A; Jiang, F; John, M; Johnson, D; Jones, C R; Joram, C; Jost, B; Jurik, N; Kandybei, S; Karacson, M; Kariuki, J M; Karodia, S; Kazeev, N; Kecke, M; Kelsey, M; Kenzie, M; Ketel, T; Khairullin, E; Khanji, B; Khurewathanakul, C; Kirn, T; Klaver, S; Klimaszewski, K; Klimkovich, T; Koliiev, S; Kolpin, M; Komarov, I; Kopecna, R; Koppenburg, P; Kosmyntseva, A; Kotriakhova, S; Kozeiha, M; Kreps, M; Krokovny, P; Kruse, F; Krzemien, W; Kucewicz, W; Kucharczyk, M; Kudryavtsev, V; Kuonen, A K; Kurek, K; Kvaratskheliya, T; Lacarrere, D; Lafferty, G; Lai, A; Lanfranchi, G; Langenbruch, C; Latham, T; Lazzeroni, C; Le Gac, R; van Leerdam, J; Leflat, A; Lefrançois, J; Lefèvre, R; Lemaitre, F; Lemos Cid, E; Leroy, O; Lesiak, T; Leverington, B; Li, P-R; Li, T; Li, Y; Li, Z; Likhomanenko, T; Lindner, R; Lionetto, F; Lisovskyi, V; Liu, X; Loh, D; Loi, A; Longstaff, I; Lopes, J H; Lucchesi, D; Lucio Martinez, M; Luo, H; Lupato, A; Luppi, E; Lupton, O; Lusiani, A; Lyu, X; Machefert, F; Maciuc, F; Macko, V; Mackowiak, P; Maddock, B; Maddrell-Mander, S; Maev, O; Maguire, K; Maisuzenko, D; Majewski, M W; Malde, S; Malinin, A; Maltsev, T; Manca, G; Mancinelli, G; Manning, P; Marangotto, D; Maratas, J; Marchand, J F; Marconi, U; Marin Benito, C; Marinangeli, M; Marino, P; Marks, J; Martellotti, G; Martin, M; Martinelli, M; Martinez Santos, D; Martinez Vidal, F; Martins Tostes, D; Massacrier, L M; Massafferri, A; Matev, R; Mathad, A; Mathe, Z; Matteuzzi, C; Mauri, A; Maurice, E; Maurin, B; Mazurov, A; McCann, M; McNab, A; McNulty, R; Mead, J V; Meadows, B; Meaux, C; Meier, F; Meinert, N; Melnychuk, D; Merk, M; Merli, A; Michielin, E; Milanes, D A; Millard, E; Minard, M-N; Minzoni, L; Mitzel, D S; Mogini, A; Molina Rodriguez, J; Mombacher, T; Monroy, I A; Monteil, S; Morandin, M; Morello, M J; Morgunova, O; Moron, J; Morris, A B; Mountain, R; Muheim, F; Mulder, M; Müller, D; Müller, J; Müller, K; Müller, V; Naik, P; Nakada, T; Nandakumar, R; Nandi, A; Nasteva, I; Needham, M; Neri, N; Neubert, S; Neufeld, N; Neuner, M; Nguyen, T D; Nguyen-Mau, C; Nieswand, S; Niet, R; Nikitin, N; Nikodem, T; Nogay, A; O'Hanlon, D P; Oblakowska-Mucha, A; Obraztsov, V; Ogilvy, S; Oldeman, R; Onderwater, C J G; Ossowska, A; Otalora Goicochea, J M; Owen, P; Oyanguren, A; Pais, P R; Palano, A; Palutan, M; Papanestis, A; Pappagallo, M; Pappalardo, L L; Pappenheimer, C; Parker, W; Parkes, C; Passaleva, G; Pastore, A; Patel, M; Patrignani, C; Pearce, A; Pellegrino, A; Penso, G; Pepe Altarelli, M; Perazzini, S; Perret, P; Pescatore, L; Petridis, K; Petrolini, A; Petrov, A; Petruzzo, M; Picatoste Olloqui, E; Pietrzyk, B; Pikies, M; Pinci, D; Pistone, A; Piucci, A; Placinta, V; Playfer, S; Plo Casasus, M; Polci, F; Poli Lener, M; Poluektov, A; Polyakov, I; Polycarpo, E; Pomery, G J; Ponce, S; Popov, A; Popov, D; Poslavskii, S; Potterat, C; Price, E; Prisciandaro, J; Prouve, C; Pugatch, V; Puig Navarro, A; Pullen, H; Punzi, G; Qian, W; Quagliani, R; Quintana, B; Rachwal, B; Rademacker, J H; Rama, M; Ramos Pernas, M; Rangel, M S; Raniuk, I; Ratnikov, F; Raven, G; Ravonel Salzgeber, M; Reboud, M; Redi, F; Reichert, S; Dos Reis, A C; Remon Alepuz, C; Renaudin, V; Ricciardi, S; Richards, S; Rihl, M; Rinnert, K; Rives Molina, V; Robbe, P; Robert, A; Rodrigues, A B; Rodrigues, E; Rodriguez Lopez, J A; Rodriguez Perez, P; Rogozhnikov, A; Roiser, S; Rollings, A; Romanovskiy, V; Romero Vidal, A; Ronayne, J W; Rotondo, M; Rudolph, M S; Ruf, T; Ruiz Valls, P; Ruiz Vidal, J; Saborido Silva, J J; Sadykhov, E; Sagidova, N; Saitta, B; Salustino Guimaraes, V; Sanchez Gonzalo, D; Sanchez Mayordomo, C; Sanmartin Sedes, B; Santacesaria, R; Santamarina Rios, C; Santimaria, M; Santovetti, E; Sarpis, G; Sarti, A; Satriano, C; Satta, A; Saunders, D M; Savrina, D; Schael, S; Schellenberg, M; Schiller, M; Schindler, H; Schlupp, M; Schmelling, M; Schmelzer, T; Schmidt, B; Schneider, O; Schopper, A; Schreiner, H F; Schubert, K; Schubiger, M; Schune, M-H; Schwemmer, R; Sciascia, B; Sciubba, A; Semennikov, A; Sergi, A; Serra, N; Serrano, J; Sestini, L; Seyfert, P; Shapkin, M; Shapoval, I; Shcheglov, Y; Shears, T; Shekhtman, L; Shevchenko, V; Siddi, B G; Silva Coutinho, R; Silva de Oliveira, L; Simi, G; Simone, S; Sirendi, M; Skidmore, N; Skwarnicki, T; Smith, E; Smith, I T; Smith, J; Smith, M; Soares Lavra, L; Sokoloff, M D; Soler, F J P; Souza De Paula, B; Spaan, B; Spradlin, P; Sridharan, S; Stagni, F; Stahl, M; Stahl, S; Stefko, P; Stefkova, S; Steinkamp, O; Stemmle, S; Stenyakin, O; Stepanova, M; Stevens, H; Stone, S; Storaci, B; Stracka, S; Stramaglia, M E; Straticiuc, M; Straumann, U; Sun, L; Sutcliffe, W; Swientek, K; Syropoulos, V; Szczekowski, M; Szumlak, T; Szymanski, M; T'Jampens, S; Tayduganov, A; Tekampe, T; Tellarini, G; Teubert, F; Thomas, E; van Tilburg, J; Tilley, M J; Tisserand, V; Tobin, M; Tolk, S; Tomassetti, L; Tonelli, D; Toriello, F; Tourinho Jadallah Aoude, R; Tournefier, E; Traill, M; Tran, M T; Tresch, M; Trisovic, A; Tsaregorodtsev, A; Tsopelas, P; Tully, A; Tuning, N; Ukleja, A; Usachov, A; Ustyuzhanin, A; Uwer, U; Vacca, C; Vagner, A; Vagnoni, V; Valassi, A; Valat, S; Valenti, G; Vazquez Gomez, R; Vazquez Regueiro, P; Vecchi, S; van Veghel, M; Velthuis, J J; Veltri, M; Veneziano, G; Venkateswaran, A; Verlage, T A; Vernet, M; Vesterinen, M; Viana Barbosa, J V; Viaud, B; Vieira, D; Vieites Diaz, M; Viemann, H; Vilasis-Cardona, X; Vitti, M; Volkov, V; Vollhardt, A; Voneki, B; Vorobyev, A; Vorobyev, V; Voß, C; de Vries, J A; Vázquez Sierra, C; Waldi, R; Wallace, C; Wallace, R; Walsh, J; Wang, J; Ward, D R; Wark, H M; Watson, N K; Websdale, D; Weiden, A; Whitehead, M; Wicht, J; Wilkinson, G; Wilkinson, M; Williams, M; Williams, M P; Williams, M; Williams, T; Wilson, F F; Wimberley, J; Winn, M A; Wishahi, J; Wislicki, W; Witek, M; Wormser, G; Wotton, S A; Wraight, K; Wyllie, K; Xie, Y; Xu, Z; Yang, Z; Yang, Z; Yao, Y; Yin, H; Yu, J; Yuan, X; Yushchenko, O; Zarebski, K A; Zavertyaev, M; Zhang, L; Zhang, Y; Zhelezov, A; Zheng, Y; Zhu, X; Zhukov, V; Zonneveld, J B; Zucchelli, S

    2017-09-15

    A highly significant structure is observed in the Λ_{c}^{+}K^{-}π^{+}π^{+} mass spectrum, where the Λ_{c}^{+} baryon is reconstructed in the decay mode pK^{-}π^{+}. The structure is consistent with originating from a weakly decaying particle, identified as the doubly charmed baryon Ξ_{cc}^{++}. The difference between the masses of the Ξ_{cc}^{++} and Λ_{c}^{+} states is measured to be 1334.94±0.72(stat.)±0.27(syst.)  MeV/c^{2}, and the Ξ_{cc}^{++} mass is then determined to be 3621.40±0.72(stat.)±0.27(syst.)±0.14(Λ_{c}^{+})  MeV/c^{2}, where the last uncertainty is due to the limited knowledge of the Λ_{c}^{+} mass. The state is observed in a sample of proton-proton collision data collected by the LHCb experiment at a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 1.7  fb^{-1}, and confirmed in an additional sample of data collected at 8 TeV.

  6. Energetic and exergetic analysis of combined cycle Energas Boca de Jaruco

    International Nuclear Information System (INIS)

    Dominguez, F. J.; Tapanez, A.; Castillo, E. del; Castillo, R.; Perez, R.

    2015-01-01

    The work shows the energy and exergy evaluation of the combined cycle Energas Boca de Jaruco, which consists of five gas turbines 30 MWh five heat recovery steam OTSGs type and a steam turbine of 150 MW. This evaluation is performed without additional burning and for different percentages of utilization of these burners. The results allow to have a criterion of the efficiency of the system with and without supplementary burned, which can define strategies most appropriate system operation. (full text)

  7. Image-guided brachytherapy for cervical cancer: analysis of D2 cc hot spot in three-dimensional and anatomic factors affecting D2 cc hot spot in organs at risk.

    Science.gov (United States)

    Kim, Robert Y; Dragovic, Alek F; Whitley, Alexander C; Shen, Sui

    2014-01-01

    To analyze the D2 cc hot spot in three-dimensional CT and anatomic factors affecting the D2 cc hot spot in organs at risk (OARs). Thirty-one patients underwent pelvic CT scan after insertion of the applicator. High-dose-rate treatment planning was performed with standard loading patterns. The D2 cc structures in OARs were generated in three dimensional if the total equivalent dose in 2 Gy exceeded our defined dose limits (hot spot). The location of D2 cc hot spot was defined as the center of the largest D2 cc fragment. The relationship between the hot spot and the applicator position was reported in Digital Imaging and Communication in Medicine coordinates. The location of sigmoid, small bowel, and bladder D2 cc hot spots was around the endocervix: The mean location of sigmoid hot spot for lateral view was 1.6 cm posteriorly and 2.3 cm superiorly (Y, 1.6 and Z, 2.3), small bowel was 1.6 cm anteriorly and 2.7 cm superiorly (Y, -1.6 and Z, 2.7). The mean location of bladder hot spot was 1.6 cm anteriorly and 1.6 cm superiorly (Y, -1.6 and Z, 1.6). These hot spots were near the plane of Point A (X, 2.0 or -2.0; Y, 0; and Z, 2.0). The mean location of rectal hot spot was 1.6 cm posteriorly and 1.9 cm inferiorly (Y, 1.6 and Z, -1.9). D2 cc hot spot was affected by uterine wall thickness, uterine tandem position, fibroids, bladder fullness, bowel gas, and vaginal packing. Because of the location of the D2 cc hot spots, larger tumors present a challenge for adequate tumor coverage with a conventional brachytherapy applicator without an interstitial implant. Additionally, anatomic factors were identified which affect the D2 cc hot spot in OARs. Copyright © 2014 American Brachytherapy Society. Published by Elsevier Inc. All rights reserved.

  8. Computational Fluid Dynamics Analysis Method Developed for Rocket-Based Combined Cycle Engine Inlet

    Science.gov (United States)

    1997-01-01

    Renewed interest in hypersonic propulsion systems has led to research programs investigating combined cycle engines that are designed to operate efficiently across the flight regime. The Rocket-Based Combined Cycle Engine is a propulsion system under development at the NASA Lewis Research Center. This engine integrates a high specific impulse, low thrust-to-weight, airbreathing engine with a low-impulse, high thrust-to-weight rocket. From takeoff to Mach 2.5, the engine operates as an air-augmented rocket. At Mach 2.5, the engine becomes a dual-mode ramjet; and beyond Mach 8, the rocket is turned back on. One Rocket-Based Combined Cycle Engine variation known as the "Strut-Jet" concept is being investigated jointly by NASA Lewis, the U.S. Air Force, Gencorp Aerojet, General Applied Science Labs (GASL), and Lockheed Martin Corporation. Work thus far has included wind tunnel experiments and computational fluid dynamics (CFD) investigations with the NPARC code. The CFD method was initiated by modeling the geometry of the Strut-Jet with the GRIDGEN structured grid generator. Grids representing a subscale inlet model and the full-scale demonstrator geometry were constructed. These grids modeled one-half of the symmetric inlet flow path, including the precompression plate, diverter, center duct, side duct, and combustor. After the grid generation, full Navier-Stokes flow simulations were conducted with the NPARC Navier-Stokes code. The Chien low-Reynolds-number k-e turbulence model was employed to simulate the high-speed turbulent flow. Finally, the CFD solutions were postprocessed with a Fortran code. This code provided wall static pressure distributions, pitot pressure distributions, mass flow rates, and internal drag. These results were compared with experimental data from a subscale inlet test for code validation; then they were used to help evaluate the demonstrator engine net thrust.

  9. Irradiation effects on C/C composite materials for high temperature nuclear applications

    International Nuclear Information System (INIS)

    Eto, M.; Ugachi, H.; Baba, S.I.; Ishiyama, S.; Ishihara, M.; Hayashi, K.

    2000-01-01

    Excellent characteristics such as high strength and high thermal shock resistance of C/C composite materials have led us to try to apply them to the high temperature components in nuclear facilities. Such components include the armour tile of the first wall and divertor of fusion reactor and the elements of control rod for the use in HTGR. One of the most important aspects to be clarified about C/C composites for nuclear applications is the effect of neutron irradiation on their properties. At the Japan Atomic Energy Research Institute (JAERI), research on the irradiation effects on various properties of C/C composite materials has been carried out using fission reactors (JRR-3, JMTR), accelerators (TANDEM, TIARA) and the Fusion Neutronics Source (FNS). Additionally, strength tests of some neutron-irradiated elements for the control rod were carried out to investigate the feasibility of C/C composites. The paper summarises the R and D activities on the irradiation effects on C/C composites. (authors)

  10. Dynamic performance of a combined gas turbine and air bottoming cycle plant for off-shore applications

    DEFF Research Database (Denmark)

    Benato, Alberto; Pierobon, Leonardo; Haglind, Fredrik

    2014-01-01

    and a combined gas turbine coupled with an air bottoming cycle plant. The case study is the Draugen off-shore oil and gas platform, located in the North Sea, Norway. The normal electricity demand is 19 MW, currently covered by two gas turbines generating each 50% of the power demand, while the third turbine......When the Norwegian government introduced the CO2 tax for hydrocarbon fuels, the challenge became to improve the performance of off-shore power systems. An oil and gas platform typically operates on an island (stand-alone system) and the power demand is covered by two or more gas turbines. In order...... to improve the plant performance, a bottoming cycle unit can be added to the gas turbine topping module, thus constituting a combined cycle plant. This paper aims at developing and testing the numerical model simulating the part-load and dynamic behavior of a novel power system, composed of two gas turbines...

  11. Combination syringe provides air-free blood samples

    Science.gov (United States)

    Pool, S. L.

    1970-01-01

    Standard syringe and spinal needle are combined in unique manner to secure air-free blood samples. Combination syringe obtains air free samples because air bubbles become insignificant when samples greater than 1 cc are drawn.

  12. The effective use of gas turbines and combined cycle technology in heat and electrical energy production

    International Nuclear Information System (INIS)

    Boehm, B.; Stark, E.

    1999-01-01

    The modernization of the energy industry in many countries is a real challenge for both, the policy makers as well as for the power industry. Especially, the efficient satisfaction of the heat and electrical demand of big cities will remain an interesting task for supply companies and hence for today engineers and economists, because the availability of natural gas from Russia and from other deposits owning countries for the decades to come, cogeneration by using modern gas turbines and combined cycle technologies is a key and corner stone of supply, not the least for its very low emission and small environmental loading. It is the intention of this paper, to demonstrate under resource to: 1) the high potential of natural gas-based cogeneration; 2) the high efficiency of gas turbines and combined cycle plants; 3) their flexibility to cover different demands; 4) the operational experience with gas turbines and combined cycle cogeneration plants; 5) the very good environmental behavior of gas turbines. Actually, the highest utilization of primary energy resources is afforded with natural gas and described technology. Future gradual rise of gas prices can bring about a shift from the present main application in high efficiency load plants to mid range load operation of cogeneration plants. (Author)

  13. Three Dimensional Numerical Simulation of Rocket-based Combined-cycle Engine Response During Mode Transition Events

    Science.gov (United States)

    Edwards, Jack R.; McRae, D. Scott; Bond, Ryan B.; Steffan, Christopher (Technical Monitor)

    2003-01-01

    The GTX program at NASA Glenn Research Center is designed to develop a launch vehicle concept based on rocket-based combined-cycle (RBCC) propulsion. Experimental testing, cycle analysis, and computational fluid dynamics modeling have all demonstrated the viability of the GTX concept, yet significant technical issues and challenges still remain. Our research effort develops a unique capability for dynamic CFD simulation of complete high-speed propulsion devices and focuses this technology toward analysis of the GTX response during critical mode transition events. Our principal attention is focused on Mode 1/Mode 2 operation, in which initial rocket propulsion is transitioned into thermal-throat ramjet propulsion. A critical element of the GTX concept is the use of an Independent Ramjet Stream (IRS) cycle to provide propulsion at Mach numbers less than 3. In the IRS cycle, rocket thrust is initially used for primary power, and the hot rocket plume is used as a flame-holding mechanism for hydrogen fuel injected into the secondary air stream. A critical aspect is the establishment of a thermal throat in the secondary stream through the combination of area reduction effects and combustion-induced heat release. This is a necessity to enable the power-down of the rocket and the eventual shift to ramjet mode. Our focus in this first year of the grant has been in three areas, each progressing directly toward the key initial goal of simulating thermal throat formation during the IRS cycle: CFD algorithm development; simulation of Mode 1 experiments conducted at Glenn's Rig 1 facility; and IRS cycle simulations. The remainder of this report discusses each of these efforts in detail and presents a plan of work for the next year.

  14. Real-world experience of women using extended-cycle vs monthly-cycle combined oral contraception in the United States: the National Health and Wellness Survey.

    Science.gov (United States)

    Nappi, Rossella E; Lete, Iñaki; Lee, Lulu K; Flores, Natalia M; Micheletti, Marie-Christine; Tang, Boxiong

    2018-01-18

    The real-world experience of women receiving extended-cycle combined oral contraception (COC) versus monthly-cycle COC has not been reported. Data were from the United States 2013 National Health and Wellness Survey. Eligible women (18-50 years old, premenopausal, without hysterectomy) currently using extended-cycle COC (3 months between periods) were compared with women using monthly-cycle COC. Treatment satisfaction (1 "extremely dissatisfied" to 7 "extremely satisfied"), adherence (8-item Morisky Medication Adherence Scale © ), menstrual cycle-related symptoms, health-related quality of life (HRQOL) and health state utilities (Medical Outcomes Short Form Survey-36v2®), depression (9-item Patient Health Questionnaire), sleep difficulties, Work Productivity and Activity Impairment-General Health, and healthcare resource use were assessed using one-way analyses of variance, chi-square tests, and generalized linear models (adjusted for covariates). Participants included 260 (6.7%) women using extended-cycle and 3616 (93.3%) using monthly-cycle COC. Women using extended-cycle COC reported significantly higher treatment satisfaction (P = 0.001) and adherence (P = 0.04) and reduced heavy menstrual bleeding (P = 0.029). A non-significant tendency toward reduced menstrual pain (39.5% versus 47.3%) and menstrual cycle-related symptoms (40.0% versus 48.7%) was found in women using extended-cycle versus monthly-cycle COC. Significantly more women using extended-cycle COC reported health-related diagnoses, indicating preferential prescription for extended-cycle COC among women reporting more health problems. Consistent with this poorer health, more women using extended-cycle COC reported fatigue, headache, and activity impairment (P values cycle COC as a valuable treatment option with high satisfaction, high adherence, and reduced heavy menstrual bleeding.

  15. Performance analysis of an Integrated Solar Combined Cycle using Direct Steam Generation in parabolic trough collectors

    International Nuclear Information System (INIS)

    Montes, M.J.; Rovira, A.; Munoz, M.; Martinez-Val, J.M.

    2011-01-01

    Highlights: → Solar hybridization improves the performance of CCGT in a very hot and dry weather. → The scheme analyzed is a DSG parabolic trough field coupled to the Rankine cycle. → An annual simulation has been carried out for two locations: Almeria and Las Vegas. → Economical analysis shows that this scheme is a cheaper way to exploit solar energy. → For that, solar hybridization must be limited to a small fraction of the CCGT power. - Abstract: The contribution of solar thermal power to improve the performance of gas-fired combined cycles in very hot and dry environmental conditions is analyzed in this work, in order to assess the potential of this technique, and to feature Direct Steam Generation (DSG) as a well suited candidate for achieving very good results in this quest. The particular Integrated Solar Combined Cycle (ISCC) power plant proposed consists of a DSG parabolic trough field coupled to the bottoming steam cycle of a Combined Cycle Gas Turbine (CCGT) power plant. For this analysis, the solar thermal power plant performs in a solar dispatching mode: the gas turbine always operates at full load, only depending on ambient conditions, whereas the steam turbine is somewhat boosted to accommodate the thermal hybridization from the solar field. Although the analysis is aimed to studying such complementary effects in the widest perspective, two relevant examples are given, corresponding to two well-known sites: Almeria (Spain), with a mediterranean climate, and Las Vegas (USA), with a hot and dry climate. The annual simulations show that, although the conventional CCGT power plant works worse in Las Vegas, owing to the higher temperatures, the ISCC system operates better in Las Vegas than in Almeria, because of solar hybridization is especially well coupled to the CCGT power plant in the frequent days with great solar radiation and high temperatures in Las Vegas. The complementary effect will be clearly seen in these cases, because the thermal

  16. Aspen Plus simulation of biomass integrated gasification combined cycle systems at corn ethanol plants

    International Nuclear Information System (INIS)

    Zheng, Huixiao; Kaliyan, Nalladurai; Morey, R. Vance

    2013-01-01

    Biomass integrated gasification combined cycle (BIGCC) systems and natural gas combined cycle (NGCC) systems are employed to provide heat and electricity to a 0.19 hm 3 y −1 (50 million gallon per year) corn ethanol plant using different fuels (syrup and corn stover, corn stover alone, and natural gas). Aspen Plus simulations of BIGCC/NGCC systems are performed to study effects of different fuels, gas turbine compression pressure, dryers (steam tube or superheated steam) for biomass fuels and ethanol co-products, and steam tube dryer exhaust treatment methods. The goal is to maximize electricity generation while meeting process heat needs of the plant. At fuel input rates of 110 MW, BIGCC systems with steam tube dryers provide 20–25 MW of power to the grid with system thermal efficiencies (net power generated plus process heat rate divided by fuel input rate) of 69–74%. NGCC systems with steam tube dryers provide 26–30 MW of power to the grid with system thermal efficiencies of 74–78%. BIGCC systems with superheated steam dryers provide 20–22 MW of power to the grid with system thermal efficiencies of 53–56%. The life-cycle greenhouse gas (GHG) emission reduction for conventional corn ethanol compared to gasoline is 39% for process heat with natural gas (grid electricity), 117% for BIGCC with syrup and corn stover fuel, 124% for BIGCC with corn stover fuel, and 93% for NGCC with natural gas fuel. These GHG emission estimates do not include indirect land use change effects. -- Highlights: •BIGCC and natural gas combined cycle systems at corn ethanol plants are simulated. •The best performance results in 25–30 MW power to grid. •The best performance results in 74–78% system thermal efficiencies. •GHG reduction for corn ethanol with BIGCC systems compared to gasoline is over 100%

  17. Identification of a cobia (Rachycentron canadum) CC chemokine gene and its involvement in the inflammatory response.

    Science.gov (United States)

    Su, Youlu; Guo, Zhixun; Xu, Liwen; Jiang, Jingzhe; Wang, Jiangyong; Feng, Juan

    2012-01-01

    The chemokines regulate immune cell migration under inflammatory and physiological conditions. We investigated a CC chemokine gene (RcCC1) from cobia (Rachycentron canadum). The full-length RcCC1 cDNA is comprised 673 nucleotides and encodes a four-cysteine arrangement 99-amino-acid protein typical of known CC chemokines. The genomic DNA of RcCC1 consists of three exons and two introns. Phylogenetic analysis showed that RcCC1 was closest to the MIP group of CC chemokines. Quantitative real-time RT-PCR (qRT-PCR) analysis revealed RcCC1 was constitutively expressed in all tissues examined, with relative strong expression in gill, blood, kidney, spleen, and head kidney. The RcCC1 transcripts in the head kidney, spleen, and liver were quickly up-regulated after stimulation with formalin-inactivated Vibrio carchariae (bacterial vaccine) or polyriboinosinic polyribocytidylic acid (poly I:C). These results indicate RcCC1 not only plays a role in homeostasis, but also may be involved in inflammatory responses to bacterial and viral infection. Copyright © 2011 Elsevier Ltd. All rights reserved.

  18. Optimization of controlled processes in combined-cycle plant (new developments and researches)

    Science.gov (United States)

    Tverskoy, Yu S.; Muravev, I. K.

    2017-11-01

    All modern complex technical systems, including power units of TPP and nuclear power plants, work in the system-forming structure of multifunctional APCS. The development of the modern APCS mathematical support allows bringing the automation degree to the solution of complex optimization problems of equipment heat-mass-exchange processes in real time. The difficulty of efficient management of a binary power unit is related to the need to solve jointly at least three problems. The first problem is related to the physical issues of combined-cycle technologies. The second problem is determined by the criticality of the CCGT operation to changes in the regime and climatic factors. The third problem is related to a precise description of a vector of controlled coordinates of a complex technological object. To obtain a joint solution of this complex of interconnected problems, the methodology of generalized thermodynamic analysis, methods of the theory of automatic control and mathematical modeling are used. In the present report, results of new developments and studies are shown. These results allow improving the principles of process control and the automatic control systems structural synthesis of power units with combined-cycle plants that provide attainable technical and economic efficiency and operational reliability of equipment.

  19. Prospective gas turbine and combined-cycle units for power engineering (a Review)

    Science.gov (United States)

    Ol'khovskii, G. G.

    2013-02-01

    The modern state of technology for making gas turbines around the world and heat-recovery combined-cycle units constructed on their basis are considered. The progress achieved in this field by Siemens, Mitsubishi, General Electric, and Alstom is analyzed, and the objectives these companies set forth for themselves for the near and more distant future are discussed. The 375-MW gas turbine unit with an efficiency of 40% produced by Siemens, which is presently the largest one, is subjected to a detailed analysis. The main specific features of this turbine are that the gas turbine unit's hot-path components have purely air cooling, due to which the installation has enhanced maneuverability. The single-shaft combined-cycle plant constructed on the basis of this turbine has a capacity of 570 MW and efficiency higher than 60%. Programs adopted by different companies for development of new-generation gas turbine units firing synthesis gas and fitted with low-emission combustion chambers and new cooling systems are considered. Concepts of rotor blades for new gas turbine units with improved thermal barrier coatings and composite blades different parts of which are made of materials selected in accordance with the conditions of their operation are discussed.

  20. Simulation of an integrated gasification combined cycle with chemical-looping combustion and carbon dioxide sequestration

    International Nuclear Information System (INIS)

    Jiménez Álvaro, Ángel; López Paniagua, Ignacio; González Fernández, Celina; Rodríguez Martín, Javier; Nieto Carlier, Rafael

    2015-01-01

    Highlights: • A chemical-looping combustion based integrated gasification combined cycle is simulated. • The energetic performance of the plant is analyzed. • Different hydrogen-content synthesis gases are under study. • Energy savings accounting carbon dioxide sequestration and storage are quantified. • A notable increase on thermal efficiency up to 7% is found. - Abstract: Chemical-looping combustion is an interesting technique that makes it possible to integrate power generation from fuels combustion and sequestration of carbon dioxide without energy penalty. In addition, the combustion chemical reaction occurs with a lower irreversibility compared to a conventional combustion, leading to attain a somewhat higher overall thermal efficiency in gas turbine systems. This paper provides results about the energetic performance of an integrated gasification combined cycle power plant based on chemical-looping combustion of synthesis gas. A real understanding of the behavior of this concept of power plant implies a complete thermodynamic analysis, involving several interrelated aspects as the integration of energy flows between the gasifier and the combined cycle, the restrictions in relation with heat balances and chemical equilibrium in reactors and the performance of the gas turbines and the downstream steam cycle. An accurate thermodynamic modeling is required for the optimization of several design parameters. Simulations to evaluate the energetic efficiency of this chemical-looping-combustion based power plant under diverse working conditions have been carried out, and a comparison with a conventional integrated gasification power plant with precombustion capture of carbon dioxide has been made. Two different synthesis gas compositions have been tried to check its influence on the results. The energy saved in carbon capture and storage is found to be significant and even notable, inducing an improvement of the overall power plant thermal efficiency of

  1. JACoW SIP4C/C++ at CERN - Status and lessons learned

    CERN Document Server

    Jensen, Steen; Dworak, Andrzej; Gourber-Pace, Marine; Hoguin, Frederic; Lauener, Joel; Locci, Frank; Sigerud, Katarina; Sliwinski, Wojciech

    2018-01-01

    After 4 years of promoting the Software Improvement Process for C/C++ (SIP4C/C++) initiative at CERN, we describe the current status for tools and procedures along with how they have been integrated into our environment. Based on feedback from four project teams, we present reasons for and against their adoption. Finally, we show how SIP4C/C++ has improved development and delivery processes as well as the first-line support of delivered products.

  2. Boron-Based Catalysts for C-C Bond-Formation Reactions.

    Science.gov (United States)

    Rao, Bin; Kinjo, Rei

    2018-05-02

    Because the construction of the C-C bond is one of the most significant reactions in organic chemistry, the development of an efficient strategy has attracted much attention throughout the synthetic community. Among various protocols to form C-C bonds, organoboron compounds are not just limited to stoichiometric reagents, but have also made great achievements as catalysts because of the easy modification of the electronic and steric impacts on the boron center. This review presents recent developments of boron-based catalysts applied in the field of C-C bond-formation reactions, which are classified into four kinds on the basis of the type of boron catalyst: 1) highly Lewis acidic borane, B(C 6 F 5 ) 3 ; 2) organoboron acids, RB(OH) 2 , and their ester derivatives; 3) borenium ions, (R 2 BL)X; and 4) other miscellaneous kinds. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  3. Optimisation of Combined Cycle Gas Turbine Power Plant in Intraday Market: Riga CHP-2 Example

    Science.gov (United States)

    Ivanova, P.; Grebesh, E.; Linkevics, O.

    2018-02-01

    In the research, the influence of optimised combined cycle gas turbine unit - according to the previously developed EM & OM approach with its use in the intraday market - is evaluated on the generation portfolio. It consists of the two combined cycle gas turbine units. The introduced evaluation algorithm saves the power and heat balance before and after the performance of EM & OM approach by making changes in the generation profile of units. The aim of this algorithm is profit maximisation of the generation portfolio. The evaluation algorithm is implemented in multi-paradigm numerical computing environment MATLab on the example of Riga CHP-2. The results show that the use of EM & OM approach in the intraday market can be profitable or unprofitable. It depends on the initial state of generation units in the intraday market and on the content of the generation portfolio.

  4. Production costs: U.S. gas turbine ampersand combined-cycle power plants

    International Nuclear Information System (INIS)

    Anon.

    1992-01-01

    This fourth edition of UDI's gas turbine O ampersand M cost report gives 1991 operation and maintenance expenses for over 450 US gas turbine power plants. Modeled on UDI's popular series of O ampersand M cost reports for US steam-electric plants, this report shows operator and plant name, plant year-in-service, installed capacity, 1991 net generation, total fuel expenses, total non-fuel O ampersand M expenses, total production costs, and current plant capitalization. Coverage includes over 90 percent of the utility-owned gas/combustion turbine and combined-cycle plants installed in the country

  5. Thermodynamic analysis of a novel integrated solar combined cycle

    International Nuclear Information System (INIS)

    Li, Yuanyuan; Yang, Yongping

    2014-01-01

    Highlights: • A novel ISCC scheme with two-stage DSG fields has been proposed and analyzed. • HRSG and steam turbine working parameters have been optimized to match the solar integration. • New scheme exhibits higher solar shares in the power output and solar-to-electricity efficiency. • Thermodynamic performances between new and reference systems have been investigated and compared. - Abstract: Integrated solar combined cycle (ISCC) systems have become more and more popular due to their high fuel and solar energy utilization efficiencies. Conventional ISCC systems with direct steam generation (DSG) have only one-stage solar input. A novel ISCC with DSG system has been proposed and analyzed in this paper. The new system consists two-stage solar input, which would significantly increase solar share in the total power output. Moreover, how and where solar energy is input into ISCC system would have impact on the solar and system overall efficiencies, which have been analyzed in the paper. It has been found that using solar heat to supply latent heat for vaporization of feedwater would be superior to that to be used for sensible heating purposes (e.g. Superheating steam). The study shows that: (1) producing both the high- and low-pressure saturated steam in the DSG trough collector could be an efficient way to improve process and system performance; (2) for a given live steam pressure, the optimum secondary and reheat steam conditions could be matched to reach the highest system thermal efficiency and net solar-to-electricity efficiency; (3) the net solar-to-electricity efficiency could reach up to 30% in the novel two-stage ISCC system, higher than that in the one-stage ISCC power plant; (4) compared with the conventional combined cycle gas turbine (CCGT) power system, lower stack temperature could be achieved, owing to the elimination of the approach-temperature-difference constraint, resulting in better thermal match in the heat recovery steam generator

  6. Cell cycle-dependent activity of the volume- and Ca2+-activated anion currents in Ehrlich lettre ascites cells

    DEFF Research Database (Denmark)

    Klausen, Thomas Kjaer; Bergdahl, Andreas; Christophersen, Palle

    2007-01-01

    Recent evidence implicates the volume-regulated anion current (VRAC) and other anion currents in control or modulation of cell cycle progression; however, the precise involvement of anion channels in this process is unclear. Here, Cl- currents in Ehrlich Lettre Ascites (ELA) cells were monitored...... during cell cycle progression, under three conditions: (i) after osmotic swelling (i.e., VRAC), (ii) after an increase in the free intracellular Ca2+ concentration (i.e., the Ca2+-activated Cl- current, CaCC), and (iii) under steady-state isotonic conditions. The maximal swelling-activated VRAC current......+ in the pipette), was unaltered from G0 to G1, but decreased in early S phase. A novel high-affinity anion channel inhibitor, the acidic di-aryl-urea NS3728, which inhibited both VRAC and CaCC, attenuated ELA cell growth, suggesting a possible mechanistic link between cell cycle progression and cell cycle...

  7. Comparison of Different Technologies for Integrated Solar Combined Cycles: Analysis of Concentrating Technology and Solar Integration

    Directory of Open Access Journals (Sweden)

    Antonio Rovira

    2018-04-01

    Full Text Available This paper compares the annual performance of Integrated Solar Combined Cycles (ISCCs using different solar concentration technologies: parabolic trough collectors (PTC, linear Fresnel reflectors (LFR and central tower receiver (CT. Each solar technology (i.e. PTC, LFR and CT is proposed to integrate solar energy into the combined cycle in two different ways. The first one is based on the use of solar energy to evaporate water of the steam cycle by means of direct steam generation (DSG, increasing the steam production of the high pressure level of the steam generator. The other one is based on the use of solar energy to preheat the pressurized air at the exit of the gas turbine compressor before it is introduced in the combustion chamber, reducing the fuel consumption. Results show that ISCC with DSG increases the yearly production while solar air heating reduces it due to the incremental pressure drop. However, air heating allows significantly higher solar-to-electricity efficiencies and lower heat rates. Regarding the solar technologies, PTC provides the best thermal results.

  8. Municipal solid wastes incineration with combined cycle: a case study from Sao Paulo

    Energy Technology Data Exchange (ETDEWEB)

    Cerda Balcazar, Juan Galvarino; Dias, Rubens Alves; Balestieri, Jose Antonio Perrella [Universidade Estadual Paulista (UNESP), Guaratingueta, SP (Brazil)], E-mails: pos09007@feg.unesp.br, rubdias@feg.unesp.br

    2010-07-01

    Large urban centers have a huge demand for electricity, for the needs of its residents, and a growing problem of management of solid waste generated by it, that becomes an public administrative and great social problem. The correct disposal of solid waste generated by large urban centers is now one of the most complex engineering problems involving logistics, safety, environment, energy spent among other tools for sound management of municipal solid waste (MSW). This study was carried out a study of the use of incinerators and residue derived fuel and MSW with combined cycles, with the aim of producing thermal and mechanical energy (this later becomes electrical energy) and solid waste treatment in Sao Paulo. We used existing models and real plants in the European Union in this case, with the aim of making it the most viable and compatible with the current context of energy planning and resource today. A technical and economic feasibility study for a plant of this nature, using the scheme, is presented. It is expected a good attractiveness of using incinerators combined-cycle, due to its high efficiency and its ability to thermoelectric generation. (author)

  9. General Data Acquisition Platform for Wireless Sensor Network Based on CC2538

    Directory of Open Access Journals (Sweden)

    Yang Zhi-Jun

    2017-01-01

    Full Text Available Wireless sensor networks are the hotspots of current research and have very wide application prospects. Its front end is a sensor that can sense and check the external world. This paper takes temperature and humidity as the research object, and builds a wireless sensor network data acquisition platform by combining the Internet of things and the WeChat public platform. The platform uses DHT11 temperature and humidity sensors and CC2538 sensor nodes to obtain the relevant data, through the server and database for data access. The combination with WeChat public platform not only allows us to view the temperature and humidity in the WeChat public, but also allows us to understand the environmental changes of the relevant detection area more conveniently and quickly. The effectiveness of the platform is also demonstrated by the collection of temperature and humidity data.

  10. The ν 1Band System of H-CC-CN (Cyanoacetylene)

    Science.gov (United States)

    Winther, F.; Klee, S.; Mellau, G.; Naı̈m, S.; Mbosei, L.; Fayt, A.

    1996-02-01

    The ν1band system of cyanoacetylene (H-CC-CN) has been observed with an effective resolution of 0.006 cm-1. ν1= 3327.37085(3) cm-1,B1= 0.15149762(2) cm-1,D1= 1.8065(3) × 10-8cm-1. Several hot bands from the statesv5= 1,v6= 1,v7= 1, 2 (l= 0 and 2), 3 (l= 1 and 3), and 4 (l= 0 and 2),v6=v7= 1 (l= 0 and 2), andv6= 1 andv7= 2 (l= 3) have also been observed and analyzed. Many bands show strong local perturbations due to interactions with states which are combinations of the modes 4, 5, 6, and 7. These perturbing states are also described quantitatively, and rovibrational constants are given.

  11. Novel combined cycle configurations for propane pre-cooled mixed refrigerant (APCI) natural gas liquefaction cycle

    International Nuclear Information System (INIS)

    Mortazavi, Amir; Alabdulkarem, Abdullah; Hwang, Yunho; Radermacher, Reinhard

    2014-01-01

    Highlights: • 10 New LNG plants driver cycle enhancement configurations were developed. • All the 14 enhancement options design variables were optimized to demonstrate their energy saving potentials. • The best driver cycle enhancement option improved the driver cycle energy efficiency by 38%. • The effects of technological advancements on the performances of the enhancement options were studied. - Abstract: A significant amount of energy is required for natural gas liquefaction. Due to the production scale of LNG plants, they consume an intensive amount of energy. Consequently, any enhancement to the energy efficiency of LNG plants will result in a considerable reduction in natural gas consumption and CO 2 emission. Compressor drivers are the main energy consumer in the LNG plants. In this paper, 14 different driver cycle enhancement options were considered. A number of these options have not been proposed for the LNG plants. The new driver cycle development was performed by analyzing and optimizing the design variables of four conventional driver cycle enhancement options. The optimization results were used to develop more efficient cycles through mitigating the active constrains and driver cycle innovations. Based on the current available technologies five of our newly developed driver cycle configurations have higher efficiency than the most efficient existing conventional driver cycle. The best developed driver cycle enhancement option improved the base driver cycle energy efficiency by 38%. The effects of technological advancement on the performances of the all driver cycle enhancement options were also considered

  12. Cloning and bioinformatics analysis of CcPILS gene of Hickory (Carya cathayensis)

    Science.gov (United States)

    Guo, Wenbin; Yuan, Huwei; Gao, Liuxiao; Guo, Haipeng; Qiu, Lingling; Xu, Dongbin; Yan, Daoliang; Zheng, Bingsong

    2017-04-01

    PILS is a key auxin efflux carrier protein in the auxin signal transduction. A CcPILS gene related to hickory (Carya carthayensis) grafting process was obtained by RACE techniques. The full length of CcPILS gene was1541bp contained a 1263bp length open reading flame (ORF). The CcPILS encoded 294 amino acids with molecular weight of 46 kDa, PI 5.38 and localized at endoplasmic reticulum membrane. The gene contained a central hydrophilic loop separating two hydrophobic domains of about five transmembrane regions each. The gene of CcPILS belonged to Clade III sub-family of PILS and its sequence had high homology with Arabidopsis. Real Time RT-PCR analysis showed that the gene expressions were weakly induced in bud, inflorescence, fruit, leaf and stem, while strongly in root. The expression levels were strongly induced and reached a peak at the third day of grafting in scion and rootstock of hickory, which were 1.45 and 3.45 times higher, respectively, compared to that of control. The results indicated that CcPILS may be involved in regulating the expression of genes related to auxin signal transduction during hickory graft process.

  13. Optimisation of Combined Cycle Gas Turbine Power Plant in Intraday Market: Riga CHP-2 Example

    Directory of Open Access Journals (Sweden)

    Ivanova P.

    2018-02-01

    Full Text Available In the research, the influence of optimised combined cycle gas turbine unit – according to the previously developed EM & OM approach with its use in the intraday market – is evaluated on the generation portfolio. It consists of the two combined cycle gas turbine units. The introduced evaluation algorithm saves the power and heat balance before and after the performance of EM & OM approach by making changes in the generation profile of units. The aim of this algorithm is profit maximisation of the generation portfolio. The evaluation algorithm is implemented in multi-paradigm numerical computing environment MATLab on the example of Riga CHP-2. The results show that the use of EM & OM approach in the intraday market can be profitable or unprofitable. It depends on the initial state of generation units in the intraday market and on the content of the generation portfolio.

  14. Energy materials coordinating committee (EMaCC). Annual technical report, fiscal year 2003

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2004-10-18

    The DOE Energy Materials Coordinating Committee (EMaCC) serves primarily to enhance coordination among the Department's materials programs and to further effective use of materials expertise within the Department. These functions are accomplished through the exchange of budgetary and planning information among program managers and through technical meetings/workshops on selected topics involving both DOE and major contractors. In addition, EMaCC assists in obtaining materials-related inputs for both intra- and interagency compilations. Topical subcommittees of the EMaCC are responsible for conducting seminars and otherwise facilitating information flow between DOE organizational units in materials areas of particular importance to the Department. The EMaCC Terms of Reference were recently modified and developed into a Charter that was approved on June 5, 2003. As a result of this reorganization, the existing subcommittees were disbanded and new subcommittees are being formed.

  15. Performance Analysis of Solar Combined Ejector-Vapor Compression Cycle Using Environmental Friendly Refrigerants

    Directory of Open Access Journals (Sweden)

    A. B. Kasaeian

    2013-04-01

    Full Text Available In this study, a new model of a solar combined ejector-vapor compression refrigeration system has been considered. The system is equipped with an internal heat exchanger to enhance the performance of the cycle. The effects of working fluid and operating conditions on the system performance including COP, entrainment ratio (ω, compression ratio (rp and exergy efficiency were investigated. Some working fluids suggested are: R114, R141b, R123, R245fa, R600a, R365mfc, R1234ze(e and R1234ze(z. The results show that R114 and R1234ze(e yield the highest COP and exergy efficiency followed by R123, R245fa, R365mfc, R141b, R152a and R600a. It is noticed that the COP value of the new solar ejector-vapor compression refrigeration cycle is higher than that of the conventional ejector cycle with R1234ze(e for all operating conditions. This paper also demonstrates that R1234ze(e will be a suitable refrigerant in the solar combined ejector-vapor compression refrigeration system, due to its environmental friendly properties and better performance. ABSTRAK: Kajian ini menganalisa model baru sistem penyejukan mampatan gabungan ejektor-wap solar.Sistem ini dilengkapi dengan penukar haba dalaman untuk meningkatkan prestasi kitaran.Kesan bendalir bekerja dan keadaan operasi pada prestasi sistem termasuk COP, nisbah pemerangkapan (ω, nisbah mampatan (rp dan kecekapan eksergi telah disiasat.Beberapa bendalir bekerja yang dicadangkan adalah: R114, R141b, R123, R245fa, R600a, R365mfc, R1234ze(e dan R1234ze(z.Hasil kajian menunjukkan R114 dan R1234ze(e menghasilkan COP dan kecekapan eksergi tertinggi diikuti oleh R123, R245fa, R365mfc, R141b, R152a dan R600a.Didapati nilai COP kitaran penyejukan mampatan bagi ejektor-wap solar baru adalah lebih tinggi daripada kitaran ejektor konvensional dengan R1234ze(e bagi semua keadaan operasi.Kertas kerja ini juga menunjukkan bahawa R1234ze(e boleh menjadi penyejuk yang sesuai dalam sistem penyejukan mampatan gabungan ejektor

  16. Energy Materials Coordinating Committee (EMaCC): Annual technical report, Fiscal year 1987

    International Nuclear Information System (INIS)

    1988-09-01

    The DOE Energy Materials Coordinating Committee (EMaCC) serves primarily to enhance coordination among the Department's materials programs and to further the effective use of materials expertise within the Department. These functions are accomplished through the exchange of budgetary and planning information among program managers and through technical meetings/workshops on selected topics involving both DOE and major contractors. This annual technical report is mandated by the EMaCC terms of reference. This report summarizes EMaCC activities for FY 1987 and describes the materials research programs of various offices and divisions within the Department

  17. Coefficient αcc in design value of concrete compressive strength

    Directory of Open Access Journals (Sweden)

    Goleš Danica

    2016-01-01

    Full Text Available Coefficient αcc introduces the effects of rate and duration of loading on compressive strength of concrete. These effects may be partially or completely compensated by the increase in concrete strength over time. Selection of the value of this coefficient, in recommended range between 0.8 and 1.0, is carried out through the National Annexes to Eurocode 2. This paper presents some considerations related to the introduction of this coefficient and its value adopted in some European countries. The article considers the effect of the adoption of conservative value αcc=0.85 on design value of compressive and flexural resistance of rectangular cross-section made of normal and high strength concrete. It analyzes the influence of different values of coefficient αcc on the area of reinforcement required to achieve the desired resistance of cross-section.

  18. CC1, a novel crenarchaeal DNA binding protein.

    Science.gov (United States)

    Luo, Xiao; Schwarz-Linek, Uli; Botting, Catherine H; Hensel, Reinhard; Siebers, Bettina; White, Malcolm F

    2007-01-01

    The genomes of the related crenarchaea Pyrobaculum aerophilum and Thermoproteus tenax lack any obvious gene encoding a single-stranded DNA binding protein (SSB). SSBs are essential for DNA replication, recombination, and repair and are found in all other genomes across the three domains of life. These two archaeal genomes also have only one identifiable gene encoding a chromatin protein (the Alba protein), while most other archaea have at least two different abundant chromatin proteins. We performed a biochemical screen for novel nucleic acid binding proteins present in cell extracts of T. tenax. An assay for proteins capable of binding to a single-stranded DNA oligonucleotide resulted in identification of three proteins. The first protein, Alba, has been shown previously to bind single-stranded DNA as well as duplex DNA. The two other proteins, which we designated CC1 (for crenarchaeal chromatin protein 1), are very closely related to one another, and homologs are restricted to the P. aerophilum and Aeropyrum pernix genomes. CC1 is a 6-kDa, monomeric, basic protein that is expressed at a high level in T. tenax. This protein binds single- and double-stranded DNAs with similar affinities. These properties are consistent with a role for CC1 as a crenarchaeal chromatin protein.

  19. Low CO2-emissions hybrid solar combined-cycle power system with methane membrane reforming

    International Nuclear Information System (INIS)

    Li, Yuanyuan; Zhang, Na; Cai, Ruixian

    2013-01-01

    Based on the principle of cascade utilization of multiple energy resources, a gas-steam combined cycle power system integrated with solar thermo-chemical fuel conversion and CO 2 capture has been proposed and analyzed. The collected solar heat at 550 °C drives the endothermic methane reforming and is converted to the produced syngas chemical exergy, and then released as high-temperature thermal energy via combustion for power generation, achieving its high-efficiency heat-power conversion. The reforming reaction is integrated with a hydrogen separation membrane, which continuously withdraws hydrogen from the reaction zone and enables nearly full methane conversion. The CO 2 enriched gas being concentrated in the retentate zone is collected and processed with pre-combustion decarbonization. The system is thermodynamically simulated using the ASPEN PLUS code. The results show that with 91% CO 2 captured, the specific CO 2 emission is 25 g/kWh. An exergy efficiency of 58% and thermal efficiency of 51.6% can be obtained. A fossil fuel saving ratio of 31.2% is achievable with a solar thermal share of 28.2%, and the net solar-to-electricity efficiency based on the gross solar heat incident on the collector is about 36.4% compared with the same gas-steam combined cycle system with an equal CO 2 removal ratio obtained by post-combustion decarbonization. - Highlights: ► A solar-assisted hybrid combined cycle power system has been proposed and analyzed. ► The system integrates power generation with solar-driven reforming and CO 2 capture. ► solar heat upgrading and high-efficiency heat-to-power conversion are achieved. ► membrane reforming enables high CH 4 conversion and pre-combustion CO 2 capture. ► The system thermodynamic performances have been investigated and compared

  20. Thermodynamic analysis of engineering solutions aimed at raising the efficiency of integrated gasification combined cycle

    Science.gov (United States)

    Gordeev, S. I.; Bogatova, T. F.; Ryzhkov, A. F.

    2017-11-01

    Raising the efficiency and environmental friendliness of electric power generation from coal is the aim of numerous research groups today. The traditional approach based on the steam power cycle has reached its efficiency limit, prompted by materials development and maneuverability performance. The rival approach based on the combined cycle is also drawing nearer to its efficiency limit. However, there is a reserve for efficiency increase of the integrated gasification combined cycle, which has the energy efficiency at the level of modern steam-turbine power units. The limit of increase in efficiency is the efficiency of NGCC. One of the main problems of the IGCC is higher costs of receiving and preparing fuel gas for GTU. It would be reasonable to decrease the necessary amount of fuel gas in the power unit to minimize the costs. The effect can be reached by raising of the heat value of fuel gas, its heat content and the heat content of cycle air. On the example of the process flowsheet of the IGCC with a power of 500 MW, running on Kuznetsk bituminous coal, by means of software Thermoflex, the influence of the developed technical solutions on the efficiency of the power plant is considered. It is received that rise in steam-air blast temperature to 900°C leads to an increase in conversion efficiency up to 84.2%. An increase in temperature levels of fuel gas clean-up to 900°C leads to an increase in the IGCC efficiency gross/net by 3.42%. Cycle air heating reduces the need for fuel gas by 40% and raises the IGCC efficiency gross/net by 0.85-1.22%. The offered solutions for IGCC allow to exceed net efficiency of analogous plants by 1.8-2.3%.

  1. Stress analysis of two-dimensional C/C composite components for HTGR's core restraint techanism

    International Nuclear Information System (INIS)

    Satoshi Hanawa; Taiju Shibata; Jyunya Sumita; Masahiro Ishihara; Tatsuo Iyoku; Kazuhiro Sawa

    2005-01-01

    Carbon fiber reinforced carbon matrix composite (C/C composite) is one of the most promising materials for HTGRs core components due to their high strength as well as high temperature resistibility. One of the most attractive applications of C/C composite is the core restraint mechanism. The core restraint mechanism is located around the reflector block and it works to tighten reactor core blocks so as to restrict un-supposition flow pass of coolant gas (bypass flow) in the core. The restriction of bypass flow reads to the high efficiency of coolant flow rate inside of the reactor core. For the future HTGRs and VHTR (Very High Temperature Reactor), it is important to develop the core restraint mechanism with C/C composite substitute for metallic materials as used for HTTR. For the application of C/C composite to core restraint mechanism, it is important to investigate the applicability of C/C composite in viewpoint of structural integrity. In the present study, supposing the application of 2D-C/C composite to core restraint mechanism, thermal stress behavior was analyzed by considering the thickness of the C/C composite and the gap between reflector block and core restraint. It was shown from the thermal stress analysis that the circumferential stress decreases with increasing the gap and that the restraint force increases with increasing the thickness. By optimizing the thickness of C/C composite and gap between reflector block and core restraint, the C/C composite is applicable to the core restraint mechanism. (authors)

  2. Thermochemical recuperative combined cycle with methane-steam reforming combustion; Tennengasu kaishitsu nensho ni yoru konbaindo saikuru hatsuden no kokoritsuka oyobi denryoku fuka heijunka taio

    Energy Technology Data Exchange (ETDEWEB)

    Kikuchi, R.; Essaki, K.; Tsutsumi, A. [The University of Tokyo, Tokyo (Japan). Dept. of Chemical System Engineering; Kaganoi, S.; Kurimura, H. [Teikoku Sekiyu Co., Tokyo (Japan); Sasaki, T.; Ogawa, T. [Toshiba Co., Tokyo (Japan)

    2000-03-10

    Thermochemical recuperative combined cycles with methane-steam reforming are proposed for improving their thermal efficiency and for peak-load leveling. For targeting higher thermal efficiency, a cycle with methane-steam reforming reaction heated by gas turbine exhaust was analyzed. The inlet temperature of gas turbine was set at 1,350 degree C. Low-pressure steam extracted from a steam turbine is mixed with methane, and then this mixture is heated by part of the gas turbine exhaust to promote a reforming reaction. The rest of the exhaust heat is used to produce steam, which drives steam turbines to generate electricity. The effect of steam-to-methane ratio (S/C) on thermal efficiency of the cycle, as well as on methane conversion, is investigated by using the ASPEN Plus process simulator. The methane feed rate was fixed at constant and S/C ratio was varied from 2.25 to 4.75. Methane conversion shows an increasing trend toward the ratio and has a maximum value of 17.9 % at S/C=4.0. Thermal efficiency for the system is about 51 % higher than that calculated for a conventional 1,300 degree C class combined cycle under similar conditions. A thermochemical recuperative combined cycle is designed for peak-load leveling. In night-time operation from 20 : 00 to 8 : 00 it stores hydrogen produced by methane steam reforming at S/C=3.9 to save power generation. The gas turbine inlet temperature is 1,330 degree C. In daytime operation from 8 : 00 to 20 : 00 the chemically recuperated combined cycle operated at S/C=2.0 is driven by the mixture of a combined cycle operated at constant load with the same methane feed rate, whereas daytime operation generated power 1.26 times larger than that of the combined cycle. (author)

  3. Energy Materials Coordinating Committee (EMaCC) Fiscal Year 1999 annual technical report

    Energy Technology Data Exchange (ETDEWEB)

    None

    2000-10-31

    The DOE Energy Materials Coordinating Committee (EMaCC) serves primarily to enhance coordination among the Department`s materials programs and to further effective use of materials expertise within the Department. These functions are accomplished through the exchange of budgetary and planning information among program managers and through technical meetings/workshops on selected topics involving both DOE and major contractors. In addition, EMaCC assists in obtaining materials-related inputs for both intra- and interagency compilations. This report summarizes EMaCC activities for FY 1999 and describes the materials research programs of various offices and divisions within the Department.

  4. Development of high conductive C/C composite tiles for plasma facing armor

    International Nuclear Information System (INIS)

    Ioki, K.; Namiki, K.; Tsujimura, S.; Toyoda, M.; Seki, M.; Takatsu, H.

    1991-01-01

    C/C composites with high thermal conductivity were developed in unidirectional, two-dimensional and felt types, and were fabricated as full-scale armor tile. Their thermal conductivity in the direction perpendicular to the plasma-side surface is 250∝550 W/mdeg C, that is comparable to that of pyrolytic graphite. It was shown by heat load tests that the C/C composites have low surface erosion characteristics and high thermal shock resistance. Various kinds of C/C composites were successfully bonded to metal substrate, and their mechanical strength and thermal shock resistance were tested. (orig.)

  5. An evaluation of the performance of an integrated solar combined cycle plant provided with air-linear parabolic collectors

    International Nuclear Information System (INIS)

    Amelio, Mario; Ferraro, Vittorio; Marinelli, Valerio; Summaria, Antonio

    2014-01-01

    An evaluation of the performance of an innovative solar system integrated in a combined cycle plant is presented, in which the heat transfer fluid flowing in linear parabolic collectors is the same oxidant air that is introduced into the combustion chamber of the plant. This peculiarity allows a great simplification of the plant. There is a 22% saving of fossil fuel results in design conditions and 15.5% on an annual basis, when the plant works at nominal volumetric flow rate in the daily hours. The net average year efficiency is 60.9% against the value of 51.4% of a reference combined cycle plant without solar integration. Moreover, an economic evaluation of the plant is carried out, which shows that the extra-cost of the solar part is recovered in about 5 years. - Highlights: • A model to calculate an innovative ISCCS (Integrated solar Combined Cycle Systems) solar plant is presented. • The plant uses air as heat transfer fluid as well as oxidant in the combustor. • The plant presents a very high thermodynamic efficiency. • The plant is very simple in comparison with existing ISCCS

  6. Dynamical analysis of critical assembly CC-1

    International Nuclear Information System (INIS)

    Aleman Fernandez, J.R.

    1990-01-01

    The computer code CC-1, elaborated for the analysis of transients in Critical Assemblies is described. The results by the program are compared with the ones presented in the Safety Report for the Critical Assembly of ''La Quebrada'' Nuclear Research Centre (CIN). 7 refs

  7. Thermoeconomic Analysis and Optimization of a New Combined Supercritical Carbon Dioxide Recompression Brayton/Kalina Cycle

    Directory of Open Access Journals (Sweden)

    S. Mohammad S. Mahmoudi

    2016-10-01

    Full Text Available A new combined supercritical CO2 recompression Brayton/Kalina cycle (SCRB/KC is proposed. In the proposed system, waste heat from a supercritical CO2 recompression Brayton cycle (SCRBC is recovered by a Kalina cycle (KC to generate additional electrical power. The performances of the two cycles are simulated and compared using mass, energy and exergy balances of the overall systems and their components. Using the SPECO (Specific Exergy Costing approach and employing selected cost balance equations for the components of each system, the total product unit costs of the cycles are obtained. Parametric studies are performed to investigate the effects on the SCRB/KC and SCRBC thermodynamic and thermoeconomic performances of key decision parameters. In addition, considering the exergy efficiency and total product unit cost as criteria, optimization is performed for the SCRBC and SCRB/KC using Engineering Equation Solver software. The results indicate that the maximum exergy efficiency of the SCRB/KC is higher than that of the SCRBC by up to 10%, and that the minimum total product unit cost of the SCRB/KC is lower than that of the SCRBC by up to 4.9%.

  8. Rapid Differentiation between Livestock-Associated and Livestock-Independent Staphylococcus aureus CC398 Clades

    Science.gov (United States)

    Larsen, Jesper; Soldanova, Katerina; Aziz, Maliha; Contente-Cuomo, Tania; Petersen, Andreas; Vandendriessche, Stien; Jiménez, Judy N.; Mammina, Caterina; van Belkum, Alex; Salmenlinna, Saara; Laurent, Frederic; Skov, Robert L.; Larsen, Anders R.; Andersen, Paal S.; Price, Lance B.

    2013-01-01

    Staphylococcus aureus clonal complex 398 (CC398) isolates cluster into two distinct phylogenetic clades based on single-nucleotide polymorphisms (SNPs) revealing a basal human clade and a more derived livestock clade. The scn and tet(M) genes are strongly associated with the human and the livestock clade, respectively, due to loss and acquisition of mobile genetic elements. We present canonical single-nucleotide polymorphism (canSNP) assays that differentiate the two major host-associated S. aureus CC398 clades and a duplex PCR assay for detection of scn and tet(M). The canSNP assays correctly placed 88 S. aureus CC398 isolates from a reference collection into the human and livestock clades and the duplex PCR assay correctly identified scn and tet(M). The assays were successfully applied to a geographically diverse collection of 272 human S. aureus CC398 isolates. The simple assays described here generate signals comparable to a whole-genome phylogeny for major clade assignment and are easily integrated into S. aureus CC398 surveillance programs and epidemiological studies. PMID:24244535

  9. Numerical Model of a Variable-Combined-Cycle Engine for Dual Subsonic and Supersonic Cruise

    Directory of Open Access Journals (Sweden)

    Victor Fernandez-Villace

    2013-02-01

    Full Text Available Efficient high speed propulsion requires exploiting the cooling capability of the cryogenic fuel in the propulsion cycle. This paper presents the numerical model of a combined cycle engine while in air turbo-rocket configuration. Specific models of the various heat exchanger modules and the turbomachinery elements were developed to represent the physical behavior at off-design operation. The dynamic nature of the model allows the introduction of the engine control logic that limits the operation of certain subcomponents and extends the overall engine operational envelope. The specific impulse and uninstalled thrust are detailed while flying a determined trajectory between Mach 2.5 and 5 for varying throttling levels throughout the operational envelope.

  10. Coupling Mo2C@C core-shell nanocrystals on 3D graphene hybrid aerogel for high-performance lithium ion battery

    Science.gov (United States)

    Xin, Hailin; Hai, Yang; Li, Dongzhi; Qiu, Zhaozheng; Lin, Yemao; Yang, Bo; Fan, Haosen; Zhu, Caizhen

    2018-05-01

    Hybrid aerogel by dispersing Mo2C@C core-shell nanocrystals into three-dimensional (3D) graphene (Mo2C@C-GA) has been successfully prepared through two-step methods. Firstly, carbon-coated MoO2 nanocrystals uniformly anchor on 3D graphene aerogel (MoO2@C-GA) via hydrothermal reaction. Then the MoO2@C-GA precursor is transformed into Mo2C@C-GA after the following carbonization process. Furthermore, the freeze-drying step plays an important role in the resulting pore size distribution of the porous networks. Moreover, graphene aerogels exhibit extremely low densities and superior electrical properties. When evaluated as anode material for lithium ion battery, Mo2C@C-GA delivers excellent rate capability and stable cycle performance when compared with C-GA and Mo2C nanoparticles. Mo2C@C-GA exhibits the initial discharge capacity of 1461.4 mA h g-1 at the current density of 0.1 A g-1, and retains a reversible capacity of 1089.8 mA h g-1 after 100 cycles at a current density of 0.1 A g-1. Even at high current density of 5 A g-1, a discharge capacity of 623.5 mA h g-1 can be still achieved. The excellent performance of Mo2C@C-GA could be attributed to the synergistic effect of Mo2C@C nanocrystals and the 3D graphene conductive network.

  11. Development of C/C composite for the core component of the high temperature gas cooled reactor

    Energy Technology Data Exchange (ETDEWEB)

    Park, J. Y.; Kim, W. J.; Ryu, W. S.; Jang, J. H

    2005-01-15

    This report reviewed a state of the art on development of C/C composite for the core components for VHTR and described the followings items. The fabrication methods of C/C composites. Summary on the JAERI report (JAERI-Res 2002-026) on the process screening test for the selection of a proper C/C composite material. Review of the proceedings presented at the GEN-IV VHTR material PMB meeting. A status of the domestic commercial C/C composite. The published property data and the characteristics of the commercial C/C composite.

  12. Development of C/C composite for the core component of the high temperature gas cooled reactor

    International Nuclear Information System (INIS)

    Park, J. Y.; Kim, W. J.; Ryu, W. S.; Jang, J. H.

    2005-01-01

    This report reviewed a state of the art on development of C/C composite for the core components for VHTR and described the followings items. The fabrication methods of C/C composites. Summary on the JAERI report (JAERI-Res 2002-026) on the process screening test for the selection of a proper C/C composite material. Review of the proceedings presented at the GEN-IV VHTR material PMB meeting. A status of the domestic commercial C/C composite. The published property data and the characteristics of the commercial C/C composite

  13. Bacillus velezensis CC09: A Potential 'Vaccine' for Controlling Wheat Diseases.

    Science.gov (United States)

    Kang, Xingxing; Zhang, Wanling; Cai, Xunchao; Zhu, Tong; Xue, Yarong; Liu, Changhong

    2018-04-11

    Biocontrol bacteria that can act like a "vaccine", stimulating plant resistance to pathogenic diseases, are still not fully elucidated. In this study, an endophytic bacterium, Bacillus velezensis CC09, labeled with green fluorescent protein, was tested for its colonization, migration, and expression of genes encoding iturin A synthetase within wheat tissues and organs as well as for protective effects against wheat take-all and spot blotch diseases. The results showed that strain CC09 not only formed biofilm on the root surface but was also widely distributed in almost every tissue, including the epidermis, cortex, and xylem vessels, and even migrated to stems and leaves, resulting in 66.67% disease-control efficacy (DCE) of take-all and 21.64% DCE of spot blotch. Moreover, the gene cluster encoding iturin A synthase under the control of the p itu promoter is expressed in B. velezensis CC09 in wheat tissues, which indicates that iturin A might contribute to the in-vivo antifungal activity and leads to the disease control. All these data suggested that strain CC09 can act like a 'vaccine' in the control of wheat diseases, with a single treatment inoculated on roots through multiple mechanisms.

  14. Efficient detection of dangling pointer error for C/C++ programs

    Science.gov (United States)

    Zhang, Wenzhe

    2017-08-01

    Dangling pointer error is pervasive in C/C++ programs and it is very hard to detect. This paper introduces an efficient detector to detect dangling pointer error in C/C++ programs. By selectively leave some memory accesses unmonitored, our method could reduce the memory monitoring overhead and thus achieves better performance over previous methods. Experiments show that our method could achieve an average speed up of 9% over previous compiler instrumentation based method and more than 50% over previous page protection based method.

  15. RB1CC1 Protein Suppresses Type II Collagen Synthesis in Chondrocytes and Causes Dwarfism*

    Science.gov (United States)

    Nishimura, Ichiro; Chano, Tokuhiro; Kita, Hiroko; Matsusue, Yoshitaka; Okabe, Hidetoshi

    2011-01-01

    RB1-inducible coiled-coil 1 (RB1CC1) functions in various processes, such as cell growth, differentiation, senescence, apoptosis, and autophagy. The conditional transgenic mice with cartilage-specific RB1CC1 excess that were used in the present study were made for the first time by the Cre-loxP system. Cartilage-specific RB1CC1 excess caused dwarfism in mice without causing obvious abnormalities in endochondral ossification and subsequent skeletal development from embryo to adult. In vitro and in vivo analysis revealed that the dwarf phenotype in cartilaginous RB1CC1 excess was induced by reductions in the total amount of cartilage and the number of cartilaginous cells, following suppressions of type II collagen synthesis and Erk1/2 signals. In addition, we have demonstrated that two kinds of SNPs (T-547C and C-468T) in the human RB1CC1 promoter have significant influence on the self-transcriptional level. Accordingly, human genotypic variants of RB1CC1 that either stimulate or inhibit RB1CC1 transcription in vivo may cause body size variations. PMID:22049074

  16. Evaluation of advanced coal gasification combined-cycle systems under uncertainty

    International Nuclear Information System (INIS)

    Frey, H.C.; Rubin, E.S.

    1992-01-01

    Advanced integrated gasification combined cycle (IGCC) systems have not been commercially demonstrated, and uncertainties remain regarding their commercial-scale performance and cost. Therefore, a probabilistic evaluation method has been developed and applied to explicitly consider these uncertainties. The insights afforded by this method are illustrated for an IGCC design featuring a fixed-bed gasifier and a hot gas cleanup system. Detailed case studies are conducted to characterize uncertainties in key measures of process performance and cost, evaluate design trade-offs under uncertainty, identify research priorities, evaluate the potential benefits of additional research, compare results for different uncertainty assumptions, and compare the advanced IGCC system to a conventional system under uncertainty. The implications of probabilistic results for research planning and technology selection are discussed in this paper

  17. Nuclear combined cycle gas turbines for variable electricity and heat using firebrick heat storage and low-carbon fuels

    International Nuclear Information System (INIS)

    Forsberg, Charles; Peterson, Per F.; McDaniel, Patrick; Bindra, Hitesh

    2017-01-01

    The world is transitioning to a low-carbon energy system. Variable electricity and industrial energy demands have been met with storable fossil fuels. The low-carbon energy sources (nuclear, wind and solar) are characterized by high-capital-costs and low-operating costs. High utilization is required to produce economic energy. Wind and solar are non-dispatchable; but, nuclear is the dispatchable energy source. Advanced combined cycle gas turbines with firebrick heat storage coupled to high-temperature reactors may enable economic variable electricity and heat production with constant full-power reactor output. Such systems efficiently couple to fluoride-salt-cooled high-temperature reactors (FHRs) with solid fuel and clean salt coolants, molten salt reactors (MSRs) with fuel dissolved in the salt coolant and salt-cooled fusion machines. Open Brayton combined cycles allow the use of natural gas, hydrogen, other fuels and firebrick heat storage for peak electricity production with incremental heat-to-electricity efficiencies from 66 to 70+% efficient. There are closed Brayton cycle options that use firebrick heat storage but these have not been investigated in any detail. Many of these cycles couple to high-temperature gas-cooled reactors (HTGRs). (author)

  18. Smart Construction of Integrated CNTs/Li4Ti5O12 Core/Shell Arrays with Superior High-Rate Performance for Application in Lithium-Ion Batteries.

    Science.gov (United States)

    Yao, Zhujun; Xia, Xinhui; Zhou, Cheng-Ao; Zhong, Yu; Wang, Yadong; Deng, Shengjue; Wang, Weiqi; Wang, Xiuli; Tu, Jiangping

    2018-03-01

    Exploring advanced high-rate anodes is of great importance for the development of next-generation high-power lithium-ion batteries (LIBs). Here, novel carbon nanotubes (CNTs)/Li 4 Ti 5 O 12 (LTO) core/shell arrays on carbon cloth (CC) as integrated high-quality anode are constructed via a facile combined chemical vapor deposition-atomic layer deposition (ALD) method. ALD-synthesized LTO is strongly anchored on the CNTs' skeleton forming core/shell structures with diameters of 70-80 nm the combined advantages including highly conductive network, large surface area, and strong adhesion are obtained in the CC-LTO@CNTs core/shell arrays. The electrochemical performance of the CC-CNTs/LTO electrode is completely studied as the anode of LIBs and it shows noticeable high-rate capability (a capacity of 169 mA h g -1 at 1 C and 112 mA h g -1 at 20 C), as well as a stable cycle life with a capacity retention of 86% after 5000 cycles at 10 C, which is much better than the CC-LTO counterpart. Meanwhile, excellent cycling stability is also demonstrated for the full cell with LiFePO 4 cathode and CC-CNTs/LTO anode (87% capacity retention after 1500 cycles at 10 C). These positive features suggest their promising application in high-power energy storage areas.

  19. Increasing thermal efficiency of Rankine cycles by using refrigeration cycles: A theoretical analysis

    International Nuclear Information System (INIS)

    Sarr, Joachim-André Raymond; Mathieu-Potvin, François

    2016-01-01

    Highlights: • A new stratagem is proposed to improve thermal efficiency of Rankine cycles. • Three new configurations are optimized by means of numerical simulations. • The Rankine-1SCR design is advantageous for 1338 different fluid combinations. • The Rankine-2SCR design is advantageous for 772 different fluid combinations. • The Rankine-3SCR design is advantageous for 768 different fluid combinations. - Abstract: In this paper, three different modifications of the basic Rankine thermodynamic cycle are proposed. The objective is to increase the thermal efficiency of power systems based on Rankine cycles. The three new systems are named “Rankine-1SCR”, “Rankine-2SCR”, and “Rankine-3SCR” cycles, and they consist of linking a refrigeration cycle to the basic Rankine cycle. The idea is to use the refrigeration cycle to create a low temperature heat sink for the Rankine cycle. These three new power plant configurations are modeled and optimized with numerical tools, and then they are compared with the basic Rankine cycle. The objective function is the thermal efficiency of the systems (i.e., net power output (kW) divided by heat rate (kW) entering the system), and the design variables are the operating temperatures within the systems. Among the 84 × 84 (i.e., 7056) possible combinations of working and cooling fluids investigated in this paper, it is shown that: (i) the Rankine-1SCR system is advantageous for 1338 different fluid combinations, (ii) the Rankine-2SCR system is advantageous for 772 different fluid combinations, and (iii) the Rankine-3SCR system is advantageous for 768 different fluid combinations.

  20. Combined factors effect of menstrual cycle and background noise on visual inspection task performance: a simulation-based task.

    Science.gov (United States)

    Wijayanto, Titis; Tochihara, Yutaka; Wijaya, Andi R; Hermawati, Setia

    2009-11-01

    It is well known that women are physiologically and psychologically influenced by the menstrual cycle. In addition, the presence of background noise may affect task performance. So far, it has proven difficult to describe how the menstrual cycle and background noise affect task performance; some researchers have found an increment of performance during menstruation or during the presence of noise, others found performance deterioration, while other still have reported no dominant effect either of the menstrual cycle in performance or of the presence of noise. However, no study to date has investigated the combinational effect between the menstrual cycle and the presence of background noise in task performance. Therefore, the purpose of this study was to examine the combined factor effect of menstrual cycle and background noise on visual inspection task performance indices by Signal Detection Theory (SDT) metrics: sensitivity index (d') and response criteria index (beta). For this purpose, ten healthy female students (21.5+/-1.08 years) with a regular menstrual cycle participated in this study. A VDT-based visual inspection task was used for the experiment in 3x2 factorial designs. Two factors, menstrual phase, pre-menstruation (PMS), menstruation (M), and post-menstruation (PM) and background noise, with 80 dB(A) background noise and without noise, were analyzed as the main factors in this study. The results concluded that the sensitivity index (d') of SDT was affected in all the menstrual cycle conditions (pbackground noise (pbackground noise was found in this study. On the other hand, no significant effect was observed in the subject's tendency in visual inspection, shown by beta along the menstrual cycle and the presence of background noise. According to the response criteria for each individual subject, the presence of noise affected the tendency of some subjects in detecting the object and making decision during the visual inspection task.

  1. Exergy efficiency analysis of ORC (Organic Rankine Cycle) and ORC-based combined cycles driven by low-temperature waste heat

    International Nuclear Information System (INIS)

    Sun, Wenqiang; Yue, Xiaoyu; Wang, Yanhui

    2017-01-01

    Highlights: • ORC-ARC and ORC-ERC driven by low-temperature waste heat are investigated. • Thermodynamic models of basic ORC, ORC-ARC, and ORC-ERC are developed. • Exergy efficiencies of ORC, ORC-ARC, and ORC-ERC are parametrically simulated. • Suitable application conditions of ORC-ARC and ORC-ERC are reported. - Abstract: There is large amount of waste heat resources in industrial processes. However, most low-temperature waste heat is directly discharged into the environment. With the advantages of being energy-efficient, enabling investment-savings and being environmentally friendly, the Organic Rankine Cycle (ORC) plays an important role in recycling energy from low-temperature waste heat. In this study, the ORC system driven by industrial low-temperature waste heat was analyzed and optimized. The impacts of the operational parameters, including evaporation temperature, condensation temperature, and degree of superheat, on the thermodynamic performances of ORC system were conducted, with R113 used as the working fluid. In addition, the ORC-based cycles, combined with the Absorption Refrigeration Cycle (ARC) and the Ejector Refrigeration Cycle (ERC), were investigated to recover waste heat from low-temperature flue gas. The uncoupled ORC-ARC and ORC-ERC systems can generate both power and cooling for external uses. The exergy efficiency of both systems decreases with the increase of the evaporation temperature of the ORC. The net power output, the refrigerating capacity and the resultant exergy efficiency of the uncoupled ORC-ARC are all higher than those of the ORC-ERC for the evaporation temperature of the basic ORC >153 °C, in the investigated application. Finally, suitable application conditions over other temperature ranges are also given.

  2. Thermal-mechanical and isothermal fatigue of IN 792 CC

    International Nuclear Information System (INIS)

    Beck, T.; Pitz, G.; Lang, K.-H.; Loehe, D.

    1997-01-01

    The cyclic deformation and lifetime behaviour of the cast Ni-base superalloy IN 792 CC was investigated both under thermal-mechanical fatigue (TMF) and isothermal fatigue (IF) conditions. During TMF the phase relations between temperature and mechanical strain were in-phase and out-of-phase, respectively. For both phase relations a similar cyclic deformation behaviour is observed. In all cases out-of-phase TMF causes tensile mean stresses, whereas in-phase TMF leads to compressive mean stresses. At T max below 800 C out-of-phase cycling results in smaller lifetimes than in-phase loading. In spite of the rather high compressive mean stresses developing at T max above 800 C, at these temperatures in-phase loading causes shorter lifetimes than out-of-phase TMF. This effect is due to the different damage mechanisms caused by in-phase and out-of-phase loadings: at higher T max considerable intergranular damage caused by in-phase loading reduces the lifetime below the respective values measured during out-of-phase TMF, after which no intergranular damage could be detected. A comparison of the TMF data with the cyclic deformation and lifetime behaviour under IF conditions shows that the material's reactions under TMF cannot be assessed satisfactorily by the results obtained from isothermal fatigue tests. (orig.)

  3. Evaluation on the model of performance predictions for on-line monitoring system for combined-cycle power plant

    International Nuclear Information System (INIS)

    Kim, Si Moon

    2002-01-01

    This paper presents the simulation model developed to predict design and off-design performance of an actual combined cycle power plant(S-Station in Korea), which would be running combined with on-line performance monitoring system in an on-line real-time fashion. The first step in thermal performance analysis is to build an accurate performance model of the power plant, in order to achieve this goal, GateCycle program has been employed in developing the model. This developed models predict design and off-design performance with a precision of one percent over a wide range of operating conditions so that on-line real-time performance monitoring can accurately establish both current performance and expected performance and also help the operator identify problems before they would be noticed

  4. Growth Comparison of Israeli Carp (Cyprinus carpio) to Different Breeding Combination

    Science.gov (United States)

    Hwang, Ju-ae; Goo, In Bon; Kim, Jung Eun; Kim, Myung Hun; Kim, Do Hee; Im, Jae Hyun; Choi, Hye-Sung; Lee, Jeong-Ho

    2016-01-01

    ABSTRACT The purpose of this study was to investigate the improvement of growth in Israeli carp (Cyprinus carpio), and the cross experiment was carried out with two strains of Israeli carp. Four combinations of Israeli carp from Jeonbuk fisheries farm and Songpu mirror carp from Heilong Jiang, China (KK; Jeonbuk ♀ × Jeonbuk ♂, KC; Jeonbuk ♀ × China ♂, CC; China ♀ × China ♂ and CK; China ♀ × Jeonbuk ♂) were developed and reared. Body length, body weight and condition factor were determined at 20, 40, 60 and 170 days post-hatch (DPH). The results showed that there were differences in growth rate of the four groups. Body length of four groups were CK > CC > KC > KK and body weight were CC > CK > KC > KK at 170 DPH. The growth perfomance of four groups were statistically significant difference (P<0.05). During the rearing, CC group had longer length and higher weight at 170 DPH compared to other three groups and also condition factor was highest in the CC group, but there was no significant difference in a survival rate. These results indicated that the growth performance mainly depended upon brooder combination but survival rate could not significantly affect brooder. PMID:28144632

  5. Effects of differently hardened brass foil laminate on the electromechanical property of externally laminated CC tapes

    Energy Technology Data Exchange (ETDEWEB)

    Bautista, Zhierwinjay; Shin, Hyung Seop [Dept. of Mechanical Design Engineering, Andong National University, Andong (Korea, Republic of); Mean, Byoung Jean; Lee, Jae Hun [SuNAM Co Ltd., Anseong (Korea, Republic of)

    2016-12-15

    The mechanical properties of REBCO coated conductor (CC) wires under uniaxial tension are largely determined by the thick component layers in the architecture, namely, the substrate and the stabilizer or even the reinforcement layer. Depending on device applications of the CC tapes, it is necessary to reinforce thin metallic foils externally to one-side or both sides of the CC tapes. Due to the external reinforcement of brass foils, it was found that this could increase the reversible strain limit from the Cu-stabilized CC tapes. In this study, the effects of differently hardened brass foil laminate on the electromechanical property of CC tapes were investigated under uniaxial tension loading. The tensile strain dependence of the critical current (I{sub c}) was measured at 77 K and self-field. Depending on whether the I{sub c} of CC tapes were measured during loading or after unloading, a reversible strain (or stress) limit could be determined, respectively. The both-sides of the Cu-stabilized CC tapes were laminated with brass foils with different hardness, namely 1/4H, 1H and EH. From the obtained results, it showed that the yield strength of the brass laminated CC tapes with EH brass foil laminate was comparable to the one of the Cu-stabilized CC tape due to its large yield strength even though its large volume fraction. It was found that the brass foil with different hardness was mainly sensitive on the stress dependence of I{sub c}, but not on the strain sensitivity due to the residual strain induced in the laminated CC tapes during unloading.

  6. Dynamic Testing of the NASA Hypersonic Project Combined Cycle Engine Testbed for Mode Transition Experiments

    Science.gov (United States)

    2011-01-01

    NASA is interested in developing technology that leads to more routine, safe, and affordable access to space. Access to space using airbreathing propulsion systems has potential to meet these objectives based on Airbreathing Access to Space (AAS) system studies. To this end, the NASA Fundamental Aeronautics Program (FAP) Hypersonic Project is conducting fundamental research on a Turbine Based Combined Cycle (TBCC) propulsion system. The TBCC being studied considers a dual flow-path inlet system. One flow-path includes variable geometry to regulate airflow to a turbine engine cycle. The turbine cycle provides propulsion from take-off to supersonic flight. The second flow-path supports a dual-mode scramjet (DMSJ) cycle which would be initiated at supersonic speed to further accelerate the vehicle to hypersonic speed. For a TBCC propulsion system to accelerate a vehicle from supersonic to hypersonic speed, a critical enabling technology is the ability to safely and effectively transition from the turbine to the DMSJ-referred to as mode transition. To experimentally test methods of mode transition, a Combined Cycle Engine (CCE) Large-scale Inlet testbed was designed with two flow paths-a low speed flow-path sized for a turbine cycle and a high speed flow-path designed for a DMSJ. This testbed system is identified as the CCE Large-Scale Inlet for Mode Transition studies (CCE-LIMX). The test plan for the CCE-LIMX in the NASA Glenn Research Center (GRC) 10- by 10-ft Supersonic Wind Tunnel (10x10 SWT) is segmented into multiple phases. The first phase is a matrix of inlet characterization (IC) tests to evaluate the inlet performance and establish the mode transition schedule. The second phase is a matrix of dynamic system identification (SysID) experiments designed to support closed-loop control development at mode transition schedule operating points for the CCE-LIMX. The third phase includes a direct demonstration of controlled mode transition using a closed loop control

  7. Thermodynamic performance simulation and concise formulas for triple-pressure reheat HRSG of gas–steam combined cycle under off-design condition

    International Nuclear Information System (INIS)

    Zhang, Guoqiang; Zheng, Jiongzhi; Yang, Yongping; Liu, Wenyi

    2016-01-01

    Highlights: • An off-design performance simulation of triple-pressure reheat HRSG is executed. • The bottoming cycle characteristics of energy transfer/conversion are analyzed. • Concise formulas for the off-design performance of bottoming cycle are proposed. • The accuracy of the formulas is verified under different load control strategies. • The errors of the formulas are generally within 1% at a load of 100–50%. - Abstract: Concise semi-theoretical, semi-empirical formulas are developed in this study to predict the off-design performance of the bottoming cycle of the gas–steam turbine combined cycle. The formulas merely refer to the key thermodynamic design parameters (full load parameters) of the bottoming cycle and off-design gas turbine exhaust temperature and flow, which are convenient in determining the overall performance of the bottoming cycle. First, a triple-pressure reheat heat recovery steam generator (HRSG) is modeled, and thermodynamic analysis is performed. Second, concise semi-theoretical, semi-empirical performance prediction formulas for the bottoming cycle are proposed through a comprehensive analysis of the heat transfer characteristics of the HRSG and the energy conversion characteristics of the steam turbine under the off-design condition. The concise formulas are found to be effective, i.e., fast, simple, and precise in obtaining the thermodynamic parameters for bottoming cycle efficiency, HRSG heat transfer capacity, HRSG efficiency, steam turbine power output, and steam turbine efficiency under the off-design condition. Accuracy is verified by comparing the concise formulas’ calculation results with the simulation results and practical operation data under different load control strategies. The calculation errors are within 1.5% (mainly less than 1% for both simulation and actual operation data) under combined cycle load (gas turbine load) ranging from 50% to 100%. However, accuracy declines sharply when the turbine

  8. Teach yourself visually Photoshop CC

    CERN Document Server

    Wooldridge, Mike

    2013-01-01

    Get savvy with the newest features and enhancements of Photoshop CC The newest version of Photoshop boasts enhanced and new features that afford you some amazing and creative ways to create images with impact, and this popular guide gets visual learners up to speed quickly. Packed with colorful screen shots that illustrate the step-by-step instructions, this visual guide is perfect for Photoshop newcomers as well as experienced users who are looking for some beginning to intermediate-level techniques to give their projects the ""wow"" factor! Veteran and bestselling authors Mik

  9. Adobe Photoshop CC for photographers

    CERN Document Server

    Evening, Martin

    2014-01-01

    Adobe Photoshop for Photographers 2014 Release by Photoshop hall-of-famer and acclaimed digital imaging professional Martin Evening has been fully updated to include detailed instruction for all of the updates to Photoshop CC 2014 on Adobe's Creative Cloud, including significant new features, such as Focus Area selections, enhanced Content-Aware filling, and new Spin and Path blur gallery effects. This guide covers all the tools and techniques photographers and professional image editors need to know when using Photoshop, from workflow guidance to core skills to advanced techniques for profess

  10. Does Core Length Taken per cc of Prostate Volume in Prostate Biopsy Affect the Diagnosis of Prostate Cancer?

    Science.gov (United States)

    Deliktas, Hasan; Sahin, Hayrettin; Cetinkaya, Mehmet; Dere, Yelda; Erdogan, Omer; Baldemir, Ercan

    2016-08-01

    The aim of this study was to determine the minimal core length to be taken per cc of prostate volume for an effective prostate biopsy. A retrospective analysis was performed on the records of 379 patients who underwent a first prostate biopsy with 12 to 16 cores under transrectal ultrasound guidance between September 2012 and April 2015. For each patient, the core length per cc of the prostate and the percentage of sampled prostate volume were calculated, and these values were compared between the patients with and without prostate cancer. A total of 348 patients were included in the study. Cancer was determined in 26.4% of patients. The mean core length taken per cc of prostate and the percentage of sampled prostate volume were determined to be 3.40 ± 0.15 mm/cc (0.26%; range, 0.08-0.63 cc) in patients with cancer and 2.75 ± 0.08 mm/cc (0.20%; range, 0.04-0.66 cc) in patients without cancer (P = .000 and P = .000), respectively. Core length taken per cc of prostate of > 3.31 mm/cc was found to be related to an increase in the rates of prostate cancer diagnosis (odds ratio, 2.84; 95% confidence interval, 1.68-4.78). The rate of cancer determination for core length taken per cc of prostate of  3.31 mm/cc, 41.1%. Core length taken per cc of prostate and the percentage of sampled prostate volume are important morphometric parameters in the determination of prostate cancer. The results of study suggest a core length per cc of the prostate of > 3.31 mm/cc as a cutoff value for quality assurance. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. Comparison of the dielectric electroactive polymer generator energy harvesting cycles

    DEFF Research Database (Denmark)

    Dimopoulos, Emmanouil; Trintis, Ionut; Munk-Nielsen, Stig

    2013-01-01

    The Dielectric ElectroActive Polymer (DEAP) generator energy harvesting cycles have been in the spotlight of the scientific interest for the past few years. Indeed, several articles have demonstrated thorough and comprehensive comparisons of the generator fundamental energy harvesting cycles......, namely Constant Charge (CC), Constant Voltage (CV) and Constant E-field (CE), based on averaged theoretical models. Yet, it has not been possible until present to validate the outcome of those comparisons via respective experimental results. In this paper, all three primary energy harvesting cycles...... are experimentally compared, based upon the coupling of a DEAP generator with a bidirectional non-isolated power electronic converter, by means of energy gain, energy harvesting efficiency and energy conversion efficiency....

  12. Power by waste heat recovery from low temperature industrial flue gas by Organic Flash Cycle (OFC) and transcritical-CO_2 power cycle: A comparative study through combined thermodynamic and economic analysis

    International Nuclear Information System (INIS)

    Mondal, Subha; De, Sudipta

    2017-01-01

    Both Organic flash cycle and transcritical CO_2 power cycle (T-CO_2 power cycle) allow cooling of hot flue gas stream to an appreciably lower temperature due to the absence of pinch limitation. In the present study, a combined thermodynamic and economic comparison is conducted between a T-CO_2 power cycle and Organic flash cycles using R-245fa and R600 as the working fluids. It is observed that work output per kg of flue gas flow rate is slightly higher for the T-CO_2 power cycle if the flue gas is allowed to cool to the corresponding lowest possible temperature in the Heat Recovery Unit (HRU). It is also observed that with maximum possible cooling of flue gas, minimum bare module costs (BMCs) for each kW power output of OFCs are somewhat higher compared to that of T-CO_2 power cycle. Minimum BMCs for each kW output of OFCs can be reduced substantially by increasing terminal temperature difference at the low temperature end of the HRU. However, the increasing terminal temperature difference at the low temperature end of the HRU is having negligible effect on BMC ($/kW) of T-CO_2 power cycle. - Highlights: • Combined thermodynamic and economic analysis done for T-CO_2 power cycle and OFC. • With highest heat recovery, T-CO_2 cycle produces slightly higher work output/kg of flue gas. • With highest heat recovery, minimum bare module costs in $/kW is slightly higher for OFCs. • Work outputs/kg of flue gas of all cycles are almost equal for these minimum BMCs. • BMCs in $/kW for OFCs sharply decrease with larger flue gas exit temperature.

  13. Clonal spread of MRSA CC398 sublineages within and between Danish pig farms

    DEFF Research Database (Denmark)

    Espinosa-Gongora, Carmen; Larsen, Jesper; Moodley, Arshnee

    Background: Methicillin-resistant Staphylococcus aureus (MRSA) CC398 is non-typeable by standard pulsed-field gel electrophoresis (PFGE) due to methylation of the SmaI site. This makes it difficult to study the epidemiology of this livestock-associated MRSA clone. In this study, we employed...... a recently developed PFGE protocol using Cfr9I, a neoschizomer of SmaI, to investigate the diversity of MRSA CC398 in Danish pig farms. The PFGE profiles displayed by isolates from pigs, environmental samples and farm workers were compared in order to understand whether farms are contaminated with multiple...... MRSA CC398 sublineages and whether specific sublineages may occur on different farms. Methods: A cross sectional study was performed in five Danish pig farms where farm workers had been shown to carry MRSA CC398 in the previous year. A total of 75 environmental and 308 animal samples were collected...

  14. Programmer's guide for the CC3 computer models of the concept for disposal of Canada's nuclear fuel waste

    International Nuclear Information System (INIS)

    Dougan, K.D.

    1996-11-01

    Atomic Energy of Canada Limited (AECL) is assessing a concept for disposing of CANDU reactor fuel waste in a vault deep in plutonic rock of the Canadian Shield. A computer program called the Systems Variability Analysis Code (SYVAC) was developed as an analytical tool for the postclosure (long-term) assessment of the concept, and for environmental assessments of other systems. SYVAC3, the third generation of the code, is an executive program that directs repeated simulation of the disposal system, which is described by the CC3 (Canadian Concept, generation 3) model. The CC3 model is comprised of the disposal vault submodel, the local geosphere submodel and the biosphere submodel. The CC3 Proarammer's Guide describes the programming philosophy and programming conventions not covered in the project standards. The guide includes a description of the overall logic for the CC3 vault, geosphere, and biosphere submodels. Each of the CC3 submodels is also isolated from the other two submbdels to create autonomous or 'stand-alone' submodels. The techniques used to isolate a CC3 submodel, and in particular to determine the submodells input and output data interface, are described. Structure charts are provided for the CC3 model and stand-alone submodels. This guide is meant as a companion document to the CC3 User's Manual. This guide does not describe how to use the CC3 software. The user should consult the CC3 User's Manual to determine how to configure, compile, link, and run the CC3 source code, as well as how to modify the data in the input files. It is intended that the CC3 code version CC305 be executed with SYVAC3 version SV309 and the Modelling Algorithm Library (ML3) version ML303, both developed for the assessment of the concept. SYVAC3-CC3-ML3 (also referred to as 'SC3') can be run on any platform containing an ANSI FORTRAN 77 compliant compiler. Recommended hardware environments are specified in the CC3 User's Manual. (author)

  15. Unsteady flow characteristic analysis of turbine based combined cycle (TBCC inlet mode transition

    Directory of Open Access Journals (Sweden)

    Jun Liu

    2015-09-01

    Full Text Available A turbine based combined cycle (TBCC propulsion system uses a turbine-based engine to accelerate the vehicle from takeoff to the mode transition flight condition, at which point, the propulsion system performs a “mode transition” from the turbine to ramjet engine. Smooth inlet mode transition is accomplished when flow is diverted from one flowpath to the other, without experiencing unstart or buzz. The smooth inlet mode transition is a complex unsteady process and it is one of the enabling technologies for combined cycle engine to become a functional reality. In order to unveil the unsteady process of inlet mode transition, the research of over/under TBCC inlet mode transition was conducted through a numerical simulation. It shows that during the mode transition the terminal shock oscillates in the inlet. During the process of inlet mode transition mass flow rate and Mach number of turbojet flowpath reduce with oscillation. While in ramjet flowpath the flow field is non-uniform at the beginning of inlet mode transition. The speed of mode transition and the operation states of the turbojet and ramjet engines will affect the motion of terminal shock. The result obtained in present paper can help us realize the unsteady flow characteristic during the mode transition and provide some suggestions for TBCC inlet mode transition based on the smooth transition of thrust.

  16. Optical implementation of (3, 3, 2) regular rectangular CC-Banyan optical network

    Science.gov (United States)

    Yang, Junbo; Su, Xianyu

    2007-07-01

    CC-Banyan network plays an important role in the optical interconnection network. Based on previous reports of (2, 2, 3) the CC-Banyan network, another rectangular-Banyan network, i.e. (3, 3, 2) rectangular CC-Banyan network, has been discussed. First, according to its construction principle, the topological graph and the routing rule of (3, 3, 2) rectangular CC-Banyan network have been proposed. Then, the optically experimental setup of (3, 3, 2) rectangular CC-Banyan network has been designed and achieved. Each stage of node switch consists of phase spatial light modulator (PSLM) and polarizing beam-splitter (PBS), and fiber has been used to perform connection between adjacent stages. PBS features that s-component (perpendicular to the incident plane) of the incident light beam is reflected, and p-component (parallel to the incident plane) passes through it. According to switching logic, under the control of external electrical signals, PSLM functions to control routing paths of the signal beams, i.e. the polarization of each optical signal is rotated or not rotated 90° by a programmable PSLM. Finally, the discussion and analysis show that the experimental setup designed here can realize many functions such as optical signal switch and permutation. It has advantages of large number of input/output-ports, compact in structure, and low energy loss. Hence, the experimental setup can be used in optical communication and optical information processing.

  17. Discovery of the doubly charmed baryon $\\Xi_{cc}^{++}$ at LHCb

    CERN Document Server

    Spradlin, Patrick

    2017-01-01

    The LHCb collaboration announced the first observation of the doubly charmed baryon $\\Xi_{cc}^{++}$, which was discovered decaying to a $\\Lambda_{c}^{+}K^{-}\\pi^{+}\\pi^{+}$ final state. A highly significant structure is found in the $\\Lambda_{c}^{+}K^{-}\\pi^{+}\\pi^{+}$ mass spectrum in proton-proton collision data collected by the LHCb experiment at center-of-mass energies of 13 TeV and 8 TeV. The peak contains $313 \\pm 33$ decays in the 13 TeV sample and $113 \\pm 21$ decays in the 8 TeV, with local significances in excess of $12\\sigma$ and $7\\sigma$ respectively. The narrow structure has a width that is consistent with experimental resolution, and its properties are consistent with those of a weakly decaying state and inconsistent with those of a strongly decaying state. The difference between the masses of the structure, identified as $\\Xi_{cc}^{++}$, and the $\\Lambda_{c}^{+}$ baryon is $1334.94 \\pm 0.72(\\mbox{stat.}) \\pm 0.27(\\mbox{syst.})\\,\\mbox{MeV}/c^{2}$, and the mass of the $\\Xi_{cc}^{++}$ baryon ...

  18. Global Analysis of Solar Neutrino Oscillations Including SNO CC Measurement

    CERN Document Server

    Bahcall, J N; Peña-Garay, C; Bahcall, John N; Peña-Garay, Carlos

    2001-01-01

    For active and sterile neutrinos, we present the globally allowed solutions for two neutrino oscillations. We include the SNO CC measurement and all other relevant solar neutrino and reactor data. Five active neutrino oscillation solutions (LMA, LOW, SMA, VAC, and Just So2) are currently allowed at 3 sigma; three sterile neutrino solutions (Just So2, SMA, and VAC) are allowed at 3 sigma. The goodness of fit is satisfactory for all eight solutions. We also investigate the robustness of the allowed solutions by carrying out global analyses with and without: 1) imposing solar model constraints on the 8B neutrino flux, 2) including the Super-Kamiokande spectral energy distribution and day-night data, 3) using an enhanced CC cross section for deuterium (due to radiative corrections), and 4) a optimistic, hypothetical reduction by a factor of three of the error of the SNO CC rate. For every analysis strategy used in this paper, the most favored solutions all involve large mixing angles: LMA, LOW, or VAC. The favore...

  19. Cross-correlation Doppler global velocimetry (CC-DGV)

    Science.gov (United States)

    Cadel, Daniel R.; Lowe, K. Todd

    2015-08-01

    A flow velocimetry method, cross-correlation Doppler global velocimetry (CC-DGV), is presented as a robust, simplified, and high dynamic range implementation of the Doppler global/planar Doppler velocimetry technique. A sweep of several gigahertz of the vapor absorption spectrum is used for each velocity sample, with signals acquired from both Doppler-shifted scattered light within the flow and a non-Doppler shifted reference beam. Cross-correlation of these signals yields the Doppler shift between them, averaged over the duration of the scan. With presently available equipment, velocities from 0 ms-1 to over 3000 ms-1 can notionally be measured simultaneously, making the technique ideal for high speed flows. The processing routine is shown to be robust against large changes in the vapor pressure of the iodine cell, benefiting performance of the system in facilities where ambient conditions cannot be easily regulated. Validation of the system was performed with measurements of a model wind turbine blade boundary layer made in a 1.83 m by 1.83 m subsonic wind tunnel for which laser Doppler velocimetry (LDV) measurements were acquired alongside the CC-DGV results. CC-DGV uncertainties of ±1.30 ms-1, ±0.64 ms-1, and ±1.11 ms-1 were determined for the orthogonal stream-wise, transverse-horizontal, and transverse-vertical velocity components, and root-mean-square deviations of 2.77 ms-1 and 1.34 ms-1 from the LDV validation results were observed for Reynolds numbers of 1.5 million and 2 million, respectively. Volumetric mean velocity measurements are also presented for a supersonic jet, with velocity uncertainties of ±4.48 ms-1, ±16.93 ms-1, and ±0.50 ms-1 for the orthogonal components, and self-validation done by collapsing the data with a physical scaling.

  20. Combined cycle solar central receiver hybrid power system study. Volume III. Appendices. Final technical report

    Energy Technology Data Exchange (ETDEWEB)

    None

    1979-11-01

    A design study for a 100 MW gas turbine/steam turbine combined cycle solar/fossil-fuel hybrid power plant is presented. This volume contains the appendices: (a) preconceptual design data; (b) market potential analysis methodology; (c) parametric analysis methodology; (d) EPGS systems description; (e) commercial-scale solar hybrid power system assessment; and (f) conceptual design data lists. (WHK)

  1. Engineering of Olfactory Receptor OlfCc1 for Directed Ligand Sensitivity

    OpenAIRE

    Berke, Allison Paige

    2013-01-01

    Abstract Engineering of Olfactory Receptor OlfCc1 for Directed Ligand Sensitivityby Allison Paige Berke Joint Doctor of Philosophywith the University of California San FranciscoUniversity of California, Berkeley Professor Song Li, ChairDue to structural similarity, OlfCc1and its mammalian analogue V2R2 are hypothesized to respond to amino acid ligands in a calcium-mediated fashion. By analyzing receptor structure and making targeted mutations, the specificity and sensitivity of the receptor s...

  2. Numerical optimization of Combined Heat and Power Organic Rankine Cycles – Part A: Design optimization

    International Nuclear Information System (INIS)

    Martelli, Emanuele; Capra, Federico; Consonni, Stefano

    2015-01-01

    This two-part paper proposes an approach based on state-of-the-art numerical optimization methods for simultaneously determining the most profitable design and part-load operation of Combined Heat and Power Organic Rankine Cycles. Compared to the usual design practice, the important advantages of the proposed approach are (i) to consider the part-load performance of the ORC at the design stage, (ii) to optimize not only the cycle variables, but also the main turbine design variables (number of stages, stage loads, rotational speed). In this first part (Part A), the design model and the optimization algorithm are presented and tested on a real-world test case. PGS-COM, a recently proposed hybrid derivative-free algorithm, allows to efficiently tackle the challenging non-smooth black-box problem. - Highlights: • Algorithm for the simultaneous optimization Organic Rakine Cycle and turbine. • Thermodynamic and economic models of boiler, cycle, turbine are developed. • Non-smooth black-box optimization problem is successfully tackled with PGS-COM. • Test cases show that the algorithm returns optimal solutions within 4 min. • Toluene outperforms MDM (a siloxane) in terms of efficiency and costs.

  3. Combination of ascorbate/epigallocatechin-3-gallate/gemcitabine synergistically induces cell cycle deregulation and apoptosis in mesothelioma cells

    Energy Technology Data Exchange (ETDEWEB)

    Martinotti, Simona [Dipartimento di Scienze e Innovazione Tecnologica, Università del Piemonte Orientale “Amedeo Avogadro”, viale T. Michel 11, 15121 Alessandria (Italy); Ranzato, Elia, E-mail: ranzato@unipmn.it [Dipartimento di Scienze e Innovazione Tecnologica, Università del Piemonte Orientale “Amedeo Avogadro”, viale T. Michel 11, 15121 Alessandria (Italy); Parodi, Monica [IRCCS A.O.U. S. Martino-IST, Istituto Nazionale per la Ricerca sul Cancro, 16132 Genova (Italy); DI.ME.S., Università degli Studi di Genova, Via L. Alberti 2, 16132 Genova (Italy); Vitale, Massimo [IRCCS A.O.U. S. Martino-IST, Istituto Nazionale per la Ricerca sul Cancro, 16132 Genova (Italy); Burlando, Bruno [Dipartimento di Scienze e Innovazione Tecnologica, Università del Piemonte Orientale “Amedeo Avogadro”, viale T. Michel 11, 15121 Alessandria (Italy)

    2014-01-01

    Malignant mesothelioma (MMe) is a poor-prognosis tumor in need of innovative therapies. In a previous in vivo study, we showed synergistic anti-MMe properties of the ascorbate/epigallocatechin-3-gallate/gemcitabine combination. We have now focused on the mechanism of action, showing the induction of apoptosis and cell cycle arrest through measurements of caspase 3, intracellular Ca{sup 2+}, annexin V, and DNA content. StellArray™ PCR technology and Western immunoblotting revealed DAPK2-dependent apoptosis, upregulation of cell cycle promoters, downregulation of cell cycle checkpoints and repression of NFκB expression. The complex of data indicates that the mixture is synergistic in inducing cell cycle deregulation and non-inflammatory apoptosis, suggesting its possible use in MMe treatment. - Highlights: • Ascorbate/epigallocathechin-gallate/gemcitabine has been tested on mesothelioma cells • A synergistic mechanism has been shown for cell cycle arrest and apoptosis • PCR-array analysis has revealed the de-regulation of apoptosis and cell cycle genes • Maximum upregulation has been found for the Death-Associated Protein Kinase-2 gene • Data suggest that the mixture could be used as a clinical treatment.

  4. Cu-catalyzed esterification reaction via aerobic oxygenation and C-C bond cleavage: an approach to α-ketoesters.

    Science.gov (United States)

    Zhang, Chun; Feng, Peng; Jiao, Ning

    2013-10-09

    The Cu-catalyzed novel aerobic oxidative esterification reaction of 1,3-diones for the synthesis of α-ketoesters has been developed. This method combines C-C σ-bond cleavage, dioxygen activation and oxidative C-H bond functionalization, as well as provides a practical, neutral, and mild synthetic approach to α-ketoesters which are important units in many biologically active compounds and useful precursors in a variety of functional group transformations. A plausible radical process is proposed on the basis of mechanistic studies.

  5. Modelling and optimization of combined cycle power plant based on exergoeconomic and environmental analyses

    International Nuclear Information System (INIS)

    Ganjehkaviri, A.; Mohd Jaafar, M.N.; Ahmadi, P.; Barzegaravval, H.

    2014-01-01

    This research paper presents a study on a comprehensive thermodynamic modelling of a combined cycle power plant (CCPP). The effects of economic strategies and design parameters on the plant optimization are also studied. Exergoeconomic analysis is conducted in order to determine the cost of electricity and cost of exergy destruction. In addition, a comprehensive optimization study is performed to determine the optimal design parameters of the power plant. Next, the effects of economic parameters variations on the sustainability, carbon dioxide emission and fuel consumption of the plant are investigated and are presented for a typical combined cycle power plant. Therefore, the changes in economic parameters caused the balance between cash flows and fix costs of the plant changes at optimum point. Moreover, economic strategies greatly limited the maximum reasonable carbon emission and fuel consumption reduction. The results showed that by using the optimum values, the exergy efficiency increases for about 6%, while CO 2 emission decreases by 5.63%. However, the variation in the cost was less than 1% due to the fact that a cost constraint was implemented. In addition, the sensitivity analysis for the optimization study was curtailed to be carried out; therefore, the optimization process and results to two important parameters are presented and discussed.

  6. Incorporating User-oriented Security into CC

    DEFF Research Database (Denmark)

    Sharp, Robin

    2009-01-01

    Current versions of the Common Criteria concentrate very heavily on technical security issues which are relevant for the design of secure systems. This approach largely ignores a number of questions which can have great significance for whether or not the system can be operated securely in an env...... not currently dealt with in CC. Tentative proposals for extensions to the current classes of SFRs will be made on the basis of the analysis of the case....

  7. Molecular and functional roles of 6C CC chemokine 19 in defense system of striped murrel Channa striatus.

    Science.gov (United States)

    Arockiaraj, Jesu; Bhatt, Prasanth; Harikrishnan, Ramasamy; Arasu, Mariadhas Valan; Al-Dhabi, Naif Abdullah

    2015-08-01

    In this study, we have reported the molecular information of chemokine-19 (Chem19) from striped murrel Channa striatus (Cs). CsCC-Chem19 cDNA sequence was 555 base pair (bp) in length which is 68bp 5' untranslated region (UTR), 339bp translated region and 149bp 3' UTR. The translated region is encoded for a polypeptide of 112 amino acids. CsCC-Chem19 peptide contains a signal sequence between 1 and 26 and an interleukin (IL) 8 like domain between 24 and 89. The multiple sequence alignment showed a 'DCCL' motif, an indispensable motif present in all CC chemokines which was conserved throughout the evolution. Phylogenetic tree showed that CsCC-Chem19 formed a cluster with chemokine 19 from fishes. Secondary structure of CsCC-Chem19 revealed that the peptide contains maximum amount of coils (61.6%) compared to α-helices (25.9%%) and β-sheet (12.5%). Further, 3D analysis indicated that the cysteine residues at 33, 34, 59 and 75 making the disulfide bridges as 33 = 59 and 34 = 75. Significantly (P coding region of CsCC-Chem19, recombinant CsCC-Chem19 protein was produced. The recombinant CsCC-Chem19 protein induced the cellular proliferation and respiratory burst activity of C. striatus peripheral blood leukocytes (PBL) in a concentration dependent manner. Moreover, the chemotactic activity showed that the recombinant CsCC-Chem19 significantly (P < 0.05) enhanced the movement of PBL of C. striatus. Conclusively, CsCC-Chem19 is a 6C CC chemokine having an ability to perform both inflammatory and homeostatic functions. However, further research is necessary to understand the potential of 6C CC chemokine 19 of C. striatus, particularly their regulatory ability on different cellular components in the defense system. Copyright © 2015 Elsevier Ltd. All rights reserved.

  8. Analysis of an electricity–cooling cogeneration system based on RC–ARS combined cycle aboard ship

    International Nuclear Information System (INIS)

    Liang, Youcai; Shu, Gequn; Tian, Hua; Liang, Xingyu; Wei, Haiqiao; Liu, Lina

    2013-01-01

    Highlights: • A novel electricity–cooling cogeneration system was used to recover waste heat aboard ships. • Performance of such RC–ARS system was investigated theoretically. • Optimal exergy output can be obtained when the vaporization pressure of RC is 300 kPa. • The exergy efficiency of cogeneration system is 5–12% higher than that of basic Rankine cycle only. - Abstract: In this paper, an electricity–cooling cogeneration system based on Rankine–absorption refrigeration combined cycle is proposed to recover the waste heat of the engine coolant and exhaust gas to generate electricity and cooling onboard ships. Water is selected as the working fluid of the Rankine cycle (RC), and a binary solution of ammonia–water is used as the working fluid of the absorption refrigeration cycle. The working fluid of RC is preheated by the engine coolant and then evaporated and superheated by the exhaust gas. The absorption cycle is powered by the heat of steam at the turbine outlet. Electricity output, cooling capacity, total exergy output, primary energy ratio (PER) and exergy efficiency are chosen as the objective functions. Results show that the amount of additional cooling output is up to 18 MW. Exergy output reaches the maximum 4.65 MW at the vaporization pressure of 300 kPa. The study reveals that the electricity–cooling cogeneration system has improved the exergy efficiency significantly: 5–12% increase compared with the basic Rankine cycle only. Primary energy ratio (PER) decreases as the vaporization pressure increases, varying from 0.47 to 0.40

  9. Comparison of algae cultivation methods for bioenergy production using a combined life cycle assessment and life cycle costing approach.

    Science.gov (United States)

    Resurreccion, Eleazer P; Colosi, Lisa M; White, Mark A; Clarens, Andres F

    2012-12-01

    Algae are an attractive energy source, but important questions still exist about the sustainability of this technology on a large scale. Two particularly important questions concern the method of cultivation and the type of algae to be used. This present study combines elements of life cycle analysis (LCA) and life cycle costing (LCC) to evaluate open pond (OP) systems and horizontal tubular photobioreactors (PBRs) for the cultivation of freshwater (FW) or brackish-to-saline water (BSW) algae. Based on the LCA, OPs have lower energy consumption and greenhouse gas emissions than PBRs; e.g., 32% less energy use for construction and operation. According to the LCC, all four systems are currently financially unattractive investments, though OPs are less so than PBRs. BSW species deliver better energy and GHG performance and higher profitability than FW species in both OPs and PBRs. Sensitivity analyses suggest that improvements in critical cultivation parameters (e.g., CO(2) utilization efficiency or algae lipid content), conversion parameters (e.g., anaerobic digestion efficiency), and market factors (e.g., costs of CO(2) and electricity, or sale prices for algae biodiesel) could alter these results. Copyright © 2012 Elsevier Ltd. All rights reserved.

  10. Assessment of Environmental and Economic Impacts of Vine-Growing Combining Life Cycle Assessment, Life Cycle Costing and Multicriterial Analysis

    Directory of Open Access Journals (Sweden)

    Giacomo Falcone

    2016-08-01

    Full Text Available The wine sector is going through a significant evolution dealing with the challenges of competition issues in international markets and with necessary commitments to sustainability improvement. In the wine supply chain, the agricultural phase represents a potential source of pollution and costs. From the farmers’ point of view, these contexts require them to be more attentive and find a compromise among environmental benefits, economic benefits, and costs linked to farming practices. This paper aims to make a sustainability assessment of different wine-growing scenarios located in Calabria (Southern Italy that combines conflicting insights, i.e., environmental and economic ones, by applying Life Cycle Assessment (LCA and Life Cycle Costing (LCC to identify the main hotspots and select the alternative scenarios closest to the ideal solution through the VIKOR multicriteria method. In particular, the latter allowed us to obtain synthetic indices for a two-dimensional sustainability assessment. Conventional practices associated to the espalier training system represent the best compromise from both environmental and economic points of view, due to the higher yield per hectare. The choices regarding Functional Unit (FU and indicators were shown to have a high influence on results.

  11. MRSA CC398 in the pig production chain

    NARCIS (Netherlands)

    Broens, E.M.; Graat, E.A.M.; Wolf, van der P.J.; Giessen, van de A.W.; Duijkeren, van E.; Wagenaar, J.A.; Nes, van A.; Mevius, D.J.; Jong, de M.C.M.

    2011-01-01

    In 2005, a distinct clone of methicillin resistant Staphylococcus aureus (MRSA CC398) was found in pigs and people in contact with pigs. The structure of the pig production chain in high technology pig husbandry enables pathogens to spread during animal trading, with an increasing prevalence in

  12. ADVANCED MONITORING TO IMPROVE COMBUSTION TURBINE/COMBINED CYCLE CT/(CC) RELIABILITY, AVAILABILITY AND MAINTAINABILITY (RAM)

    Energy Technology Data Exchange (ETDEWEB)

    Leonard Angello

    2003-09-30

    Power generators are concerned with the maintenance costs associated with the advanced turbines that they are purchasing. Since these machines do not have fully established operation and maintenance (O&M) track records, power generators face financial risk due to uncertain future maintenance costs. This risk is of particular concern, as the electricity industry transitions to a competitive business environment in which unexpected O&M costs cannot be passed through to consumers. These concerns have accelerated the need for intelligent software-based diagnostic systems that can monitor the health of a combustion turbine in real time and provide valuable information on the machine's performance to its owner/operators. Such systems would interpret sensor and instrument outputs, correlate them to the machine's condition, provide interpretative analyses, forward projections of servicing intervals, estimate remaining component life, and identify faults. EPRI, Impact Technologies, Boyce Engineering, and Progress Energy have teamed to develop a suite of intelligent software tools integrated with a diagnostic monitoring platform that will, in real time, interpret data to assess the ''total health'' of combustion turbines. The Combustion Turbine Health Management System (CTHM) will consist of a series of dynamic link library (DLL) programs residing on a diagnostic monitoring platform that accepts turbine health data from existing monitoring instrumentation. The CTHM system will be a significant improvement over currently available techniques for turbine monitoring and diagnostics. CTHM will interpret sensor and instrument outputs, correlate them to a machine's condition, provide interpretative analyses, project servicing intervals, and estimate remaining component life. In addition, it will enable real-time anomaly detection and diagnostics of performance and mechanical faults, enabling power producers to more accurately predict critical component remaining useful life and turbine degradation.

  13. Association of Children’s Urinary CC16 Levels with Arsenic Concentrations in Multiple Environmental Media

    Directory of Open Access Journals (Sweden)

    Paloma I. Beamer

    2016-05-01

    Full Text Available Arsenic exposure has been associated with decreased club cell secretory protein (CC16 levels in adults. Further, both arsenic exposure and decreased levels of CC16 in childhood have been associated with decreased adult lung function. Our objective was to determine if urinary CC16 levels in children are associated with arsenic concentrations in environmental media collected from their homes. Yard soil, house dust, and tap water were taken from 34 homes. Urine and toenail samples were collected from 68 children. All concentrations were natural log-transformed prior to data analysis. There were associations between urinary CC16 and arsenic concentration in soil (b = −0.43, p = 0.001, R2 = 0.08, water (b = −0.22, p = 0.07, R2 = 0.03, house dust (b = −0.37, p = 0.07, R2 = 0.04, and dust loading (b = −0.21, p = 0.04, R2 = 0.04. In multiple analyses, only the concentration of arsenic in soil was associated with urinary CC16 levels (b = −0.42, p = 0.02, R2 = 0.14 (full model after accounting for other factors. The association between urinary CC16 and soil arsenic may suggest that localized arsenic exposure in the lungs could damage the airway epithelium and predispose children for diminished lung function. Future work to assess this possible mechanism should examine potential associations between airborne arsenic exposures, CC16 levels, lung function, and other possible confounders in children in arsenic-impacted communities.

  14. Energy materials coordinating committee (EMaCC). Annual technical report, fiscal year 2002

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2003-08-08

    The DOE Energy Materials Coordinating Committee (EMaCC) serves primarily to enhance coordination among the Department's materials programs and to further effective use of materials expertise within the Department. These functions are accomplished through the exchange of budgetary and planning information among program managers and through technical meetings/workshops on selected topics involving both DOE and major contractors. In addition, EMaCC assists in obtaining materials-related inputs for both intra- and interagency compilations. Topical subcommittees of the EMaCC are responsible for conducting seminars and otherwise facilitating information flow between DOE organizational units in materials areas of particular importance to the Department. The EMaCC Terms of Reference were recently modified and developed into a Charter that was approved on June 5, 2003. As a result of this reorganization, the existing subcommittees were disbanded and new subcommittees are being formed. The EMaCC Charter and the memorandum approving it are presented in the Appendix of this report. The FY 2002 budget summary for DOE Materials Activities is presented on page 8. The distribution of these funds between DOE laboratories, private industry, academia and other organizations is presented in tabular form on page 10. Following the budget summary is a set of detailed program descriptions for the FY 2002 DOE Materials activities. These descriptions are presented according to the organizational structure of the Department. A mission statement, a budget summary listing the project titles and FY 2002 funding, and detailed project summaries are presented for each Assistant Secretary office, the Office of Science, and the National Nuclear Security Administration. The project summaries also provide DOE, laboratory, academic and industrial contacts for each project, as appropriate.

  15. The Accident Analysis Due to Reactivity Insertion of RSG GAS 3.55 g U/cc Silicide Core

    International Nuclear Information System (INIS)

    Endiah Puji-Hastuti; Surbakti, Tukiran

    2004-01-01

    The fuels of RSG-GAS reactor was changed from uranium oxide with 250 g U of loading or 2.96 g U/cc of fuel loading to uranium silicide with the same loading. The silicide fuels can be used in higher density, staying longer in the reactor core and hence having a longer cycle length. The silicide fuel in RSG-GAS core was made up in step-wise by using mixed up core Firstly, it was used silicide fuel with 250 g U of loading and then, silicide fuel with 300 g U of loading (3.55 g U/cc of fuel loading). In every step-wise of fuel loading, it must be analyzed its safety margin. In this occasion, the reactivity accident of RSG-GAS core with 300 g U of silicide fuel loading is analyzed. The calculation was done using EUREKA-2/RR code available at P2TRR. The calculation was done by reactivity insertion at start up and power rangers. The worst case accident is transient due to control rod with drawl failure at start up by means of lowest initial power (0.1 W), either in power range. From all cases which have been done, the results of analysis showed that there is no anomaly and safety margin break at RSG-GAS core with 300 g U silicide fuel loading. (author)

  16. Tetrafluorophenolate of HBED-CC: a versatile conjugation agent for 68Ga-labeled small recombinant antibodies

    International Nuclear Information System (INIS)

    Eder, Matthias; Waengler, Bjoern; Eisenhut, Michael; Knackmuss, Stefan; LeGall, Fabrice; Little, Melvyn; Haberkorn, Uwe; Mier, Walter

    2008-01-01

    The success of 68 Ga-labeled peptides for positron emission tomography of neuroendocrine tumors is mainly depending on the complex chemistry of this radioisotope. 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA), the chelator of choice has however limitations if its application is expanded to heat-sensitive proteins. Recombinant antibodies like single chain Fv or diabodies belong to this class of proteins. They are suited to provide imaging contrast despite the short-lived 68 Ga because of their rapid blood clearances and nanomolar affinities. The heterobifunctional agent N,N'-bis[2-hydroxy-5-(carboxyethyl)benzyl]ethylenediamine-N,N'-diacetic acid (HBED-CC) was chosen as an alternative ligand because this agent is complexing [ 68 Ga]Ga 3+ much faster than DOTA at ambient temperatures. A versatile technology for HBED-CC conjugation of proteins and 68 Ga-labeling has been developed. This included HBED-CC-tetrafluorophenol (TFP) ester synthesis, coupling to the antibody at various pH and complexation reactions performed in 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES) buffer under different conditions. The synthesis of the monoreactive 2,3,5,6-tetrafluorophenolate of HBED-CC at a carboxyl group not participating in complex formation used [Fe(HBED-CC)] - for ester formation. The removal of Fe 3+ from purified (HBED-CC)TFP ester was achieved with RP 18 cartridge technology. The conjugation chemistry was performed with mAb425 which binds to the epidermal growth factor receptor (EGFR). This protein was used for optimizing purposes only. The influence of complexation parameters like temperature, pH, reaction time, and HBED-CC/antibody ratio on the biological activity of this model antibody was investigated. Furthermore, the outcome of this labeling procedure on the biological activity of a recombinant diabody (50 kDa) was studied. It is known that small HBED-CC/antibody ratios are prerequisites for minimal interference of labels with antigen

  17. Mapping the heparin-binding site of the BMP antagonist gremlin by site-directed mutagenesis based on predictive modelling.

    Science.gov (United States)

    Tatsinkam, Arnold Junior; Mulloy, Barbara; Rider, Christopher C

    2015-08-15

    Gremlin is a member of the CAN (cerberus and DAN) family of secreted BMP (bone morphogenetic protein) antagonists and also an agonist of VEGF (vascular endothelial growth factor) receptor-2. It is critical in limb skeleton and kidney development and is re-expressed during tissue fibrosis. Gremlin binds strongly to heparin and heparan sulfate and, in the present study, we sought to investigate its heparin-binding site. In order to explore a putative non-contiguous binding site predicted by computational molecular modelling, we substituted a total of 11 key arginines and lysines located in three basic residue sequence clusters with homologous sequences from cerberus and DAN (differential screening selected gene abberative in neuroblastoma), CAN proteins which lack basic residues in these positions. A panel of six Myc-tagged gremlin mutants, MGR-1-MGR-6 (MGR, mutant gremlin), each containing different combinations of targeted substitutions, all showed markedly reduced affinity for heparin as demonstrated by their NaCl elution on heparin affinity chromatography, thus verifying our predictions. Both MGR-5 and MGR-6 retained BMP-4-binding activity comparable to that of wild-type gremlin. Low-molecular-mass heparin neither promoted nor inhibited BMP-4 binding. Finally, glutaraldehyde cross-linking demonstrated that gremlin forms non-covalent dimers, similar behaviour to that of DAN and also PRDC (protein related to cerberus and DAN), another CAN protein. The resulting dimer would possess two heparin-binding sites, each running along an exposed surface on the second β-strand finger loop of one of the monomers. © 2015 Authors; published by Portland Press Limited.

  18. Energy Materials Coordinating Committee (EMaCC): Annual technical report, fiscal year 1993

    Energy Technology Data Exchange (ETDEWEB)

    1994-07-01

    The DOE Energy Materials Coordinating Committee (EMaCC) serves primarily to enhance coordination among the Department`s materials programs and to further effective use of materials expertise within the Department. These functions are accomplished through the exchange of budgetary and planning information among program managers and through technical meetings/workshops on selected topics involving both DOE and major contractors. In addition, EMaCC assists in obtaining materials-related inputs for both intra- and interagency compilations. This report summarizes EMaCC activities for FY 1993 and describes the materials research programs of various offices and divisions within the Department. The program descriptions consist of a funding summary for each Assistant Secretary office and the Office of Energy Research, and detailed project summaries with project goals and accomplishments. The FY 1993 budget summary table for DOE Materials Activities in each of the programs is presented.

  19. Oxidative electrochemical aryl C-C coupling of spiropyrans

    NARCIS (Netherlands)

    Ivashenko, Oleksii; van Herpt, Jochem T.; Rudolf, Petra; Feringa, Ben L.; Browne, Wesley R.

    2013-01-01

    The isolation and definitive assignment of the species formed upon electrochemical oxidation of nitro-spiropyran (SP) is reported. The oxidative aryl C-C coupling at the indoline moiety of the SP radical cation to form covalent dimers of the ring-closed SP form is demonstrated. The coupling is

  20. Promising Direction of Perfection of the Utilization Combine Cycle Gas Turbine Units

    Directory of Open Access Journals (Sweden)

    Gabdullina Albina I.

    2017-01-01

    Full Text Available Issues of improving the efficiency of combined cycle gas turbines (CCGT recovery type have been presented. Efficiency gas turbine plant reaches values of 45 % due to rise in temperature to a gas turbine to 1700 °C. Modern technologies for improving the cooling gas turbine components and reducing the excess air ratio leads to a further increase of the efficiency by 1-2 %. Based on research conducted at the Tomsk Polytechnic University, it shows that the CCGT efficiency can be increased by 2-3 % in the winter time due to the use of organic Rankine cycle, low-boiling substances, and air-cooled condensers (ACC. It is necessary to apply the waste heat recovery with condensation of water vapor from the flue gas, it will enhance the efficiency of the CCGT by 2-3 % to increase the efficiency of the heat recovery steam boiler (HRSB to 10-12 %. Replacing electric pumps gas turbine engine (GTE helps to reduce electricity consumption for auxiliary needs CCGT by 0.5-1.5 %. At the same time the heat of flue gas turbine engine may be useful used in HRSB, thus will increase the capacity and efficiency of the steam turbine.

  1. Exergy-based method for analyzing the composition of the electricity cost generated in gas-fired combined cycle plants

    Energy Technology Data Exchange (ETDEWEB)

    Sarraf Borelli, Samuel Jose [Promon Engenharia Ltda., Av. Presidente Juscelino Kubitschek, 1830, Itaim, CEP:04543-900 Sao Paulo/SP (Brazil)], E-mail: sborelli@terra.com.br; Oliveira Junior, Silvio de [Environmental and Thermal Engineering Laboratory, Polytechnic School, University of Sao Paulo, Av. Prof. Luciano Gualberto, 1289, Cidade Universitaria, CEP:05508-900 Sao Paulo/SP (Brazil)], E-mail: silvio.oliveira@poli.usp.br

    2008-02-15

    The proposed method to analyze the composition of the cost of electricity is based on the energy conversion processes and the destruction of the exergy through the several thermodynamic processes that comprise a combined cycle power plant. The method uses thermoeconomics to evaluate and allocate the cost of exergy throughout the processes, considering costs related to inputs and investment in equipment. Although the concept may be applied to any combined cycle or cogeneration plant, this work develops only the mathematical modeling for three-pressure heat recovery steam generator (HRSG) configurations and total condensation of the produced steam. It is possible to study any nx1 plant configuration (n sets of gas turbine and HRSGs associated to one steam turbine generator and condenser) with the developed model, assuming that every train operates identically and in steady state. The presented model was conceived from a complex configuration of a real power plant, over which variations may be applied in order to adapt it to a defined configuration under study [Borelli SJS. Method for the analysis of the composition of electricity costs in combined cycle thermoelectric power plants. Master in Energy Dissertation, Interdisciplinary Program of Energy, Institute of Eletro-technical and Energy, University of Sao Paulo, Sao Paulo, Brazil, 2005 (in Portuguese)]. The variations and adaptations include, for instance, use of reheat, supplementary firing and partial load operation. It is also possible to undertake sensitivity analysis on geometrical equipment parameters.

  2. Exergy-based method for analyzing the composition of the electricity cost generated in gas-fired combined cycle plants

    Energy Technology Data Exchange (ETDEWEB)

    Borelli, Samuel Jose Sarraf [Promon Engenharia Ltda., Av. Presidente Juscelino Kubitschek, 1830, Itaim, CEP:04543-900 Sao Paulo/SP (Brazil); De Oliveira Junior, Silvio [Environmental and Thermal Engineering Laboratory, Polytechnic School, University of Sao Paulo, Av. Prof. Luciano Gualberto, 1289, Cidade Universitaria, CEP:05508-900 Sao Paulo/SP (Brazil)

    2008-02-15

    The proposed method to analyze the composition of the cost of electricity is based on the energy conversion processes and the destruction of the exergy through the several thermodynamic processes that comprise a combined cycle power plant. The method uses thermoeconomics to evaluate and allocate the cost of exergy throughout the processes, considering costs related to inputs and investment in equipment. Although the concept may be applied to any combined cycle or cogeneration plant, this work develops only the mathematical modeling for three-pressure heat recovery steam generator (HRSG) configurations and total condensation of the produced steam. It is possible to study any n x 1 plant configuration (n sets of gas turbine and HRSGs associated to one steam turbine generator and condenser) with the developed model, assuming that every train operates identically and in steady state. The presented model was conceived from a complex configuration of a real power plant, over which variations may be applied in order to adapt it to a defined configuration under study [Borelli SJS. Method for the analysis of the composition of electricity costs in combined cycle thermoelectric power plants. Master in Energy Dissertation, Interdisciplinary Program of Energy, Institute of Eletro-technical and Energy, University of Sao Paulo, Sao Paulo, Brazil, 2005 (in Portuguese)]. The variations and adaptations include, for instance, use of reheat, supplementary firing and partial load operation. It is also possible to undertake sensitivity analysis on geometrical equipment parameters. (author)

  3. Exergy-based method for analyzing the composition of the electricity cost generated in gas-fired combined cycle plants

    International Nuclear Information System (INIS)

    Sarraf Borelli, Samuel Jose; Oliveira Junior, Silvio de

    2008-01-01

    The proposed method to analyze the composition of the cost of electricity is based on the energy conversion processes and the destruction of the exergy through the several thermodynamic processes that comprise a combined cycle power plant. The method uses thermoeconomics to evaluate and allocate the cost of exergy throughout the processes, considering costs related to inputs and investment in equipment. Although the concept may be applied to any combined cycle or cogeneration plant, this work develops only the mathematical modeling for three-pressure heat recovery steam generator (HRSG) configurations and total condensation of the produced steam. It is possible to study any nx1 plant configuration (n sets of gas turbine and HRSGs associated to one steam turbine generator and condenser) with the developed model, assuming that every train operates identically and in steady state. The presented model was conceived from a complex configuration of a real power plant, over which variations may be applied in order to adapt it to a defined configuration under study [Borelli SJS. Method for the analysis of the composition of electricity costs in combined cycle thermoelectric power plants. Master in Energy Dissertation, Interdisciplinary Program of Energy, Institute of Eletro-technical and Energy, University of Sao Paulo, Sao Paulo, Brazil, 2005 (in Portuguese)]. The variations and adaptations include, for instance, use of reheat, supplementary firing and partial load operation. It is also possible to undertake sensitivity analysis on geometrical equipment parameters

  4. Emergence of a novel subpopulation of CC398 Staphylococcus aureus infecting animals is a serious hazard for humans

    Directory of Open Access Journals (Sweden)

    Nathalie Laure Van Der Mee-Marquet

    2014-12-01

    Full Text Available Until recently, Staphylococcus aureus from clonal complex (CC398 were mostly described as colonizing asymptomatic raised pigs and pig-farmers. Currently, the epidemiology of the CC398 lineage is becoming more complex. CC398 human-adapted isolates are increasingly being identified in bloodstream infections in humans living in animal-free environments. In addition, CC398 isolates are increasingly responsible for invasive infections in various animals. CC398 isolates that colonize asymptomatic pigs and the isolates that infect humans living in animal-free environments (human-adapted isolates both lack several clinically important S. aureus–associated virulence factors but differ on the basis of their prophage content. Recent findings have provided insight into the influence of a φMR11-like helper prophage on the ability of CC398 isolates to infect humans. To assess the recent spread of the CC398 lineage to various animal species and to investigate the links between the φMR11-like prophage and the emergence of CC398 isolates infecting animals, we studied 277 isolates causing infections in unrelated animals. The prevalence of CC398 isolates increased significantly between 2007 and 2013 (p<0.001; 31.8 % of the animal isolates harbored the φMR11-like prophage. High-density DNA microarray experiments with 37 representative infected-animal isolates positive for φMR11-like DNA established that most infected-animal isolates carried many genetic elements related to antimicrobial resistance and virulence genes, and a φ3 prophage encoding immune-modulating proteins and associated with animal-to-human jumps. Our findings suggest recent clonal expansion and dissemination of a new subpopulation of CC398 isolates, responsible for invasive infections in various animals, with a considerable potential to colonize and infect humans, probably greater than that of human-adapted CC398 isolates, justifying active surveillance.

  5. Effective energy management by combining gas turbine cycles and forward osmosis desalination process

    International Nuclear Information System (INIS)

    Park, Min Young; Shin, Serin; Kim, Eung Soo

    2015-01-01

    Highlights: • Innovative gas turbine system and FO integrated system was proposed. • The feasibility of the integrated system was analyzed thermodynamically. • GOR of the FO–gas turbine system is 17% higher than those of MED and MSF. • Waste heat utilization of the suggested system is 85.7%. • Water production capacity of the suggested system is 3.5 times higher than the MSF–gas turbine system. - Abstract: In the recent years, attempts to improve the thermal efficiency of the gas turbine cycles have been made. In order to enhance the energy management of the gas turbine cycle, a new integration concept has been proposed; integration of gas turbine cycle and forward osmosis desalination process. The combination of the gas turbine cycle and the forward osmosis (FO) desalination process basically implies the coupling of the waste heat from the gas turbine cycle to the draw solute recovery system in the FO process which is the most energy consuming part of the whole FO process. By doing this, a strong system that is capable of producing water and electricity with very little waste heat can be achieved. The feasibility of this newly proposed system was analyzed using UNISIM program and the OLI property package. For the analysis, the thermolytic draw solutes which has been suggested by other research groups have been selected and studied. Sensitivity analysis was conducted on the integration system in order to understand and identify the key parameters of the integrated system. And the integrated system was further evaluated by comparing the gain output ratio (GOR) values with the conventional desalination technologies such as multi stage flash (MSF) and multi effect distillation (MED). The suggested integrated system was calculated to have a GOR of 14.8, while the MSF and MED when integrated to the gas turbine cycle showed GOR value of 12. It should also be noted that the energy utilization of the suggested integrated system is significantly higher by 27

  6. Induction of heat-labile sites in DNA of mammalian cells by the antitumor alkylating drug CC-1065

    International Nuclear Information System (INIS)

    Zsido, T.J.; Woynarowski, J.M.; Baker, R.M.; Gawron, L.S.; Beerman, T.A.

    1991-01-01

    CC-1065 is a very potent antitumor antibiotic capable of covalent and noncovalent binding to the minor groove of naked DNA. Upon thermal treatment, covalent adducts formed between CC-1065 and DNA generate strand break. The authors have shown that this molecular damage can be detected following CC-1065 treatment of mammalian whole cells. Using alkaline sucrose gradient analysis, They observe thermally induced breakage of [ 14 C]thymidine-prelabeled DNA from drug-treated African green monkey kidney BSC-1 cells. Very little damage to cellular DNA by CC-1065 can be detected without first heating the drug-treated samples. CC-1065 can also generate heat-labile sites within DNA during cell lysis and heating, subsequent to the exposure of cells to drug, suggesting that a pool of free and noncovalently bound drug is available for posttreatment adduct formation. This effect was controlled for by mixing [ 3 H]thymidine-labeled untreated cells with the [ 14 C]thymidine-labeled drug-treated samples. The lowest drug dose at which heat-labile sites were detected was 3 nM CC-1065 (3 single-stranded breaks/10 6 base pairs). This concentration reduced survival of BSC-1 cells to 0.1% in cytotoxicity assays. The generation of CC-1065-induced lesions in cellular DNA is time dependent (the frequency of lesions caused by a 60 nM treatment reaching a plateau at 2 h) and is not readily reversible. The results of this study demonstrate that CC-1065 does generate heat-labile sites with the cellular DNA of intact cells and suggest that a mechanism of cytotoxic action of CC-1065 involves formation of covalent adducts to DNA

  7. Analysis of embryo morphokinetics, multinucleation and cleavage anomalies using continuous time-lapse monitoring in blastocyst transfer cycles.

    Science.gov (United States)

    Desai, Nina; Ploskonka, Stephanie; Goodman, Linnea R; Austin, Cynthia; Goldberg, Jeffrey; Falcone, Tommaso

    2014-06-20

    Time-lapse imaging combined with embryo morphokinetics may offer a non-invasive means for improving embryo selection. Data from clinics worldwide are necessary to compare and ultimately develop embryo classifications models using kinetic data. The primary objective of this study was to determine if there were kinetic differences between embryos with limited potential and those more often associated with in vitro blastocyst formation and/or implantation. We also wanted to compare putative kinetic markers for embryo selection as proposed by other laboratories to what we were observing in our own laboratory setting. Kinetic data and cycle outcomes were retrospectively analyzed in patients age 39 and younger with 7 or more zygotes cultured in the Embryoscope. Timing of specific events from the point of insemination were determined using time-lapse (TL) imaging. The following kinetic markers were assessed: time to syngamy (tPNf), t2, time to two cells (c), 3c (t3), 4c ( t4), 5c (t5), 8c (t8), morula (tMor), start of blastulation (tSB); tBL, blastocyst (tBL); expanded blastocyst (tEBL). Durations of the second (cc2) and third (cc3) cell cycles, the t5-t2 interval as well as time to complete synchronous divisions s1, s2 and s3 were calculated. Incidence and impact on development of nuclear and cleavage anomalies were also assessed. A total of 648 embryos transferred on day 5 were analyzed. The clinical pregnancy and implantation rate were 72% and 50%, respectively. Morphokinetic data showed that tPNf, t2,t4, t8, s1, s2,s3 and cc2 were significantly different in embryos forming blastocysts (ET or frozen) versus those with limited potential either failing to blastulate or else forming poor quality blastocysts ,ultimately discarded. Comparison of embryo kinetics in cycles with all embryos implanting (KID+) versus no implantation (KID-) suggested that markers of embryo competence to implant may be different from ability to form a blastocyst. The incidence of multinucleation

  8. Energy Materials Coordinating Committee (EMaCC). Annual technical report, Fiscal Year 2001

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2002-08-01

    The DOE Energy Materials Coordinating Committee (EMaCC) serves primarily to enhance coordination among the Department's materials programs and to further effective use of materials expertise within the Department. These functions are accomplished through the exchange of budgetary and planning information among program managers and through technical meetings/workshops on selected topics involving both DOE and major contractors. In addition, EMaCC assists in obtaining materials-related inputs for both intra- and interagency compilations.

  9. Multidisciplinary design of a rocket-based combined cycle SSTO launch vehicle using Taguchi methods

    Science.gov (United States)

    Olds, John R.; Walberg, Gerald D.

    1993-01-01

    Results are presented from the optimization process of a winged-cone configuration SSTO launch vehicle that employs a rocket-based ejector/ramjet/scramjet/rocket operational mode variable-cycle engine. The Taguchi multidisciplinary parametric-design method was used to evaluate the effects of simultaneously changing a total of eight design variables, rather than changing them one at a time as in conventional tradeoff studies. A combination of design variables was in this way identified which yields very attractive vehicle dry and gross weights.

  10. Combined nutritional and environmental life cycle assessment of fruits and vegetables

    DEFF Research Database (Denmark)

    Stylianou, Katerina S.; Fantke, Peter; Jolliet, Olivier

    2016-01-01

    -LCA) framework that compares environmental and nutritional effects of foods in a common end -point metric, Disability Adjusted Life Years (DALY). In the assessment, environmental health impact categories include green house gases, particulate matter (PM), and pesticide residues on fruits and vegetables, while......; 35 μDALY/serving fruit benefit compared to a factor 10 lower impact. Replacing detrimental foods, such as trans-fat and red meat, with fruits or vegetables further enhances health benefit. This study illustrates the importance of considering nutritional effects in food-LCA.......Nutritional health effects from the ‘use stage’ of the life cycle of food products can be substantial, especially for fruits and vegetables. To assess potential one-serving increases in fruit and vegetable consumption in Europe, we employ the Combined Nutritional and Environmental LCA (CONE...

  11. Effect of salt stress on the physiology of Frankia sp strain CcI6

    Indian Academy of Sciences (India)

    2013-10-01

    Oct 1, 2013 ... the strain is closely related to Frankia sp. strain CcI3. ... [Oshone R, Mansour SR and Tisa LS 2013 Effect of salt stress on the physiology of Frankia sp strain CcI6. .... This work was supported in part by US-Egypt Joint Research.

  12. Overall performance assessment of a combined cycle power plant: An exergo-economic analysis

    International Nuclear Information System (INIS)

    Sahin, Ahmet Z.; Al-Sharafi, Abdullah; Yilbas, Bekir S.; Khaliq, Abdul

    2016-01-01

    Highlights: • An exergo-economic analysis is carried out for a combined cycle power plant. • An overall performance index (OPI) is defined to analyze the power plant. • Four performance indicators and three scenarios are considered in the analysis. • The optimum configuration of the power plant differs for each scenarios considered. - Abstract: An exergo-economic analysis is carried out for a combined cycle power plant using the first law and the second law of thermodynamics, and the economic principles while incorporating GT PRO/PEACE Software Packages. An overall performance index (OPI) is defined to assess and analyze the optimum operational and design configurations of the power plant. Four performance indicators are considered for the analysis; namely, energy efficiency (ENE), exergy efficiency (EXE), levelized cost of electricity (COE), and the total investment (TI) cost. Three possible scenarios are considered in which different weight factor is assigned to the performance indicators when assessing the performance. These scenarios are: (i) the conventional case in which the levelized cost of electricity is given a high priority, (ii) environmental conscious case in which the exergy efficiency is given a high priority, and (iii) the economical case in which the total cost of investment is given a high priority. It is shown that the optimum size and the configuration of the power plant differ for each scenarios considered. The selection and optimization of the size and configuration of the power plant are found to be depending on the user priorities and the weight factors assigned to the performance indicators.

  13. A Scramjet Compression System for Hypersonic Air Transportation Vehicle Combined Cycle Engines

    Directory of Open Access Journals (Sweden)

    Devendra Sen

    2018-06-01

    Full Text Available This paper proposes a compression system for a scramjet, to be used as part of a combined cycle engine on a hypersonic transport vehicle that can achieve sustained flight at 8 Mach 8. Initially research into scramjet compression system and shock wave interaction was conducted to establish the foundation of the scramjet inlet and isolator sections. A Computational Fluid Dynamics (CFD campaign was conducted, where the shock structure and flow characteristics was analysed between Mach 4.5–8. The compression system of a scramjet is of crucial importance in providing air at suitable Mach number, pressure and temperature to the combustion chamber. The use of turbojet engines in over-under configuration with the scramjet was investigated as well as the study of a combined cycle scramjet-ramjet configuration. It was identified that locating the scramjet in the centre with a rotated ramjet on either side, where its ramps make up the scramjet wall was the most optimal configuration, as it mitigated the effect of the oblique shocks propagating from the scramjet walls into the adjacent ramjet. Furthermore, this meant that the forebody of the vehicle could solely be used as the compression surface by the scramjet. In this paper, the sizing of the scramjet combustion chamber and nozzle were modified to match the flow properties of the oncoming flow with the purpose of producing the most optimum scramjet configuration for the cruise speed of Mach 8. CFD simulations showed that the scramjet inlet did not provide the levels of compression and stagnation pressure recovery initially required. However, it was found that the scramjet provided significantly more thrust than the drag of the aircraft at sustained Mach 8 flight, due to its utilisation of a very aerodynamic vehicle design.

  14. Valuing flexibility: The case of an Integrated Gasification Combined Cycle power plant

    International Nuclear Information System (INIS)

    Abadie, Luis M.; Chamorro, Jose M.

    2008-01-01

    In this paper we analyze the choice between two technologies for producing electricity. In particular, the firm has to decide whether and when to invest either in a Natural Gas Combined Cycle (NGCC) power plant or in an Integrated Gasification Combined Cycle (IGCC) power plant, which may burn either coal or natural gas. Instead of assuming that fuel prices follow standard geometric Brownian motions, here they are assumed to show mean reversion, specifically to follow an inhomogeneous geometric Brownian motion. First we consider the opportunity to invest in a NGCC power plant. We derive the optimal investment rule as a function of natural gas price and the remaining life of the right to invest. In addition, the analytical solution for a perpetual option to invest is obtained. Then we turn to the IGCC power plant. We analyse the valuation of an operating plant when there are switching costs between modes of operation, and the choice of the best operation mode. This serves as an input to evaluate the option to invest in this plant. Finally we derive the value of an opportunity to invest either in a NGCC or IGCC power plant, i.e. to choose between an inflexible and a flexible technology, respectively. Depending on the opportunity's time to maturity, we derive the pairs of coal and gas prices for which it is optimal to invest in NGCC, in IGCC, or simply not to invest. Numerical computations involve the use of one- and two-dimensional binomial lattices that support a mean-reverting process for coal and gas prices. Basic parameter values are taken from an actual IGCC power plant currently in operation. Sensitivity of some results with respect to the underlying stochastic process for fuel price is also checked

  15. Conventional and advanced exergetic analyses applied to a combined cycle power plant

    International Nuclear Information System (INIS)

    Petrakopoulou, Fontina; Tsatsaronis, George; Morosuk, Tatiana; Carassai, Anna

    2012-01-01

    Conventional exergy-based methods pinpoint components and processes with high irreversibilities. However, they lack certain insight. For a given advanced technological state, there is a minimum level of exergy destruction related to technological and/or economic constraints that is unavoidable. Furthermore, in any thermodynamic system, exergy destruction stems from both component interactions (exogenous) and component inefficiencies (endogenous). To overcome the limitations of the conventional analyses and to increase our knowledge about a plant, advanced exergy-based analyses have been developed. In this paper, a combined cycle power plant is analyzed using both conventional and advanced exergetic analyses. Except for the expander of the gas turbine system and the high-pressure steam turbine, most of the exergy destruction in the plant components is unavoidable. This unavoidable part is constrained by internal technological limitations, i.e. each component’s endogenous exergy destruction. High levels of endogenous exergy destruction show that component interactions do not contribute significantly to the thermodynamic inefficiencies. In addition, these inefficiencies are unavoidable to a large extent. With the advanced analysis, new improvement strategies are revealed that could not otherwise be found. -- Highlights: ► This is the first application of a complete advanced exergetic analysis to a complex power plant. ► In the three-pressure-level combined cycle power plant studied here, the improvement potential of the majority of the components is low, since most of the exergy destruction is unavoidable. ► Component interactions are generally of lower importance for the considered plant. ► Splitting the exogenous exergy destruction reveals one-to-one component interactions and improvement strategies. ► The advanced exergetic analysis is a necessary supplement to the conventional analysis in improving a complex system.

  16. Optimization of the rocket mode trajectory in a rocket based combined cycle (RBCC) engine powered SSTO vehicle

    Science.gov (United States)

    Foster, Richard W.

    1989-07-01

    The application of rocket-based combined cycle (RBCC) engines to booster-stage propulsion, in combination with all-rocket second stages in orbital-ascent missions, has been studied since the mid-1960s; attention is presently given to the case of the 'ejector scramjet' RBCC configuration's application to SSTO vehicles. While total mass delivered to initial orbit is optimized at Mach 20, payload delivery capability to initial orbit optimizes at Mach 17, primarily due to the reduction of hydrogen fuel tankage structure, insulation, and thermal protection system weights.

  17. Effects of cytokine combinations on the cell cycle and early apoptosis of irradiated umbilical cord blood AC133+ cells

    International Nuclear Information System (INIS)

    Liu Yulong; Dai Hong; Jiang Zhong; Zhou Liying; Guo Xiaokui; Zhou Jianying

    2005-01-01

    The cell cycle and early apoptosis of 2.5 Gy 6 MV-X ray irradiated umbilical cord blood AC133 + cells cultured with cytokine combinations (IL-3 + FL + SCF) were immunolabelled and analyzed by flow cytometry at d 0, 1, 2, 3 and 7. The result of flow cytometry analysis showed that majority of irradiated umbilical cord blood AC133 + cells were in G 0 /G 1 phase of the cell cycle at d 0. Under the influence of cytokine combinations (IL-3 + FL + SCF), nearly 50% of cells were in S phase on 3rd day. AC133 + cells irradiated were in vitro incubated in the medium without cytokines, nearly all cells died by apoptosis. However, when we incubated cells with cytokine combinations (IL-3 + FL + SCF), (38.0 ± 6.8)% of cells were saved from apoptosis at d 2. The more percent of saved AC133 + cells became to proliferate with the extension of culture. In short, cytokine combinations (IL-3 + FL + SCF) could have a key role to protect irradiated cells and partially avoid induction of apoptosis by ionizing radiation in hematopoietics stem/progenitor cells. (authors)

  18. Technology development life cycle processes.

    Energy Technology Data Exchange (ETDEWEB)

    Beck, David Franklin

    2013-05-01

    This report and set of appendices are a collection of memoranda originally drafted in 2009 for the purpose of providing motivation and the necessary background material to support the definition and integration of engineering and management processes related to technology development. At the time there was interest and support to move from Capability Maturity Model Integration (CMMI) Level One (ad hoc processes) to Level Three. As presented herein, the material begins with a survey of open literature perspectives on technology development life cycles, including published data on %E2%80%9Cwhat went wrong.%E2%80%9D The main thrust of the material presents a rational expose%CC%81 of a structured technology development life cycle that uses the scientific method as a framework, with further rigor added from adapting relevant portions of the systems engineering process. The material concludes with a discussion on the use of multiple measures to assess technology maturity, including consideration of the viewpoint of potential users.

  19. Synergistic Anticancer Effects of Vorinostat and Epigallocatechin-3-Gallate against HuCC-T1 Human Cholangiocarcinoma Cells

    Directory of Open Access Journals (Sweden)

    Tae Won Kwak

    2013-01-01

    Full Text Available The aim of this study was to investigate the effect of the combination of vorinostat and epigallocatechin-3-gallate against HuCC-T1 human cholangiocarcinoma cells. A novel chemotherapy strategy is required as cholangiocarcinomas rarely respond to conventional chemotherapeutic agents. Both vorinostat and EGCG induce apoptosis and suppress invasion, migration, and angiogenesis of tumor cells. The combination of vorinostat and EGCG showed synergistic growth inhibitory effects and induced apoptosis in tumor cells. The Bax/Bcl-2 expression ratio and caspase-3 and -7 activity increased, but poly (ADP-ribose polymerase expression decreased when compared to treatment with each agent alone. Furthermore, invasion, matrix metalloproteinase (MMP expression, and migration of tumor cells decreased following treatment with the vorinostat and EGCG combination compared to those of vorinostat or EGCG alone. Tube length and junction number of human umbilical vein endothelial cells (HUVECs decreased as well as vascular endothelial growth factor expression following vorinostat and EGCG combined treatment. These results indicate that the combination of vorinostat and EGCG had a synergistic effect on inhibiting tumor cell angiogenesis potential. We suggest that the combination of vorinostat and EGCG is a novel option for cholangiocarcinoma chemotherapy.

  20. Cytotoxicity and cell-cycle effects of paclitaxel when used as a single agent and in combination with ionizing radiation

    International Nuclear Information System (INIS)

    Gupta, Nalin; Hu, Lily J.; Deen, Dennis F.

    1997-01-01

    Purpose: This study aimed to determine the extent of paclitaxel-induced cytotoxicity and cell-cycle perturbations when used alone and in combination with radiation in human glioma cells. Methods and Materials: The effect of paclitaxel alone on three human glioma cells lines--SF-126, U-87 MG, and U-251 MG--was assessed after 24, 48, 72, or 96 h treatment. For experiments in combination with radiation, cells were exposed to either a long (48-h) or short (8-h) duration of paclitaxel treatment prior to irradiation. Cell survival was determined by clonogenic assay. Cell cycle perturbations were assessed by using flow cytometry to measure the proportion of cells in G 1 , S, and G 2 /M phases. Results: When cells were treated with paclitaxel alone for ≥24 h, cytotoxicity increased up to a threshold dose, after which it plateaued. When treatment duration was ≤24 h, cytotoxicity was appreciably greater in U-251 MG cells than in SF-126 and U-87 MG cells. After 24 h of paclitaxel treatment, cells in plateau phase growth had increased survival compared to cells in log phase growth. In contrast, after 8 h paclitaxel treatment, mitotic cells had reduced survival compared to cells from an asynchronous population. Cell-cycle perturbations were consistent with the presence of a mitotic block after paclitaxel treatment, although changes in other cell-cycle phase fractions varied among cell lines. For experiments in combination with radiation, cytotoxicity was increased when cells were irradiated after 48 h of paclitaxel treatment but not after 8 h of treatment. Conclusion: The duration of paclitaxel treatment and the location of cells in the cell cycle modify the degree of radiation cytotoxicity. The mechanisms of paclitaxel cytotoxicity are likely to be multifactorial because varying effects are seen in different cell lines. Furthermore, it is clear that simply increasing the number of cells in G 2 /M is insufficient in itself to increase the response of cells to radiation

  1. Life cycle and reproductive patterns of Triatoma rubrofasciata (De Geer, 1773) (Hemiptera: Reduviidae), under laboratory conditions.

    Science.gov (United States)

    Braga, M V; Pinto, Z T; Lima, M M

    1998-01-01

    The life cycle and reproductive patterns of Triatoma rubrofasciata were studied along with laboratory conditions for the establishment of a prolific colony. The insects were divided into four groups: two of them were maintained at room temperature (20.5 degrees C to 33 degrees C and 85% +/- 5% of relative humidity), the other two in a climatic chamber (CC) (temperature: 29 degrees C, humidity: 80% +/- 5%). The groups were fed weekly or fortnightly on Swiss mice. The females from the group kept in the CC and fed weekly had longer life span, as well as a higher number of eggs, fertile eggs and hatchings; the group kept in the CC and fed fortnightly had a shorter life span for the 1st, 2nd and 3rd instars and a lower mortality rate for all instars. It was concluded that a constant high temperature (CC at 29 degrees C) is the most suitable condition for the maintenance of a colony of T. rubrofasciata regardless of the interval between repasts.

  2. Rh-Catalyzed decarbonylative coupling with alkynes via C-C activation of isatins.

    Science.gov (United States)

    Zeng, Rong; Dong, Guangbin

    2015-02-04

    Herein we report a [5 + 2 - 1] transformation though catalytic decarbonylative coupling between isatins and alkynes, which provides a unique way to synthesize 2-quinolinone derivatives. A broad range of alkynes can be coupled efficiently with high regioselectivity. This reaction is proposed to go through C-C activation of isatins, followed by decarbonylation and alkyne insertion. Directing group (DG) plays a critical role in this transformation. Assisted by the DG, the C-C cleavage of isatins occurs at room temperature.

  3. COMBINED CYCLE GAS TURBINE FOR THERMAL POWER STATIONS: EXPERIENCE IN DESIGNING AND OPERATION, PROSPECTS IN APPLICATION

    Directory of Open Access Journals (Sweden)

    N. V. Karnitsky

    2014-01-01

    Full Text Available The paper has reviewed main world tendencies in power consumption and power system structure. Main schemes of combined cycle gas turbines have been considered in the paper. The paper contains an operational analysis of CCGT blocks that are operating within the Belarusian energy system. The analysis results have been given in tables showing main operational indices of power blocks

  4. An NMR study of the covalent and noncovalent interactions of CC-1065 and DNA

    International Nuclear Information System (INIS)

    Scahill, T.A.; Jensen, R.M.; Swenson, D.H.; Hatzenbuhler, N.T.; Petzold, G.; Wierenga, W.; Brahme, N.D.

    1990-01-01

    The binding of the antitumor drug CC-1065 has been studied with nuclear magnetic resonance (NMR) spectroscopy. This study involves two parts, the elucidation of the covalent binding site of the drug to DNA and a detailed investigation of the noncovalent interactions of CC-1065 with a DNA fragment through analysis of 2D NOE (NOESY) experiments. A CC-1065-DNA adduct was prepared, and an adenine adduct was released upon heating. NMR ( 1 H and 13 C) analysis of the adduct shows that the drug binds to N3 of adenine by reaction of its cyclopropyl group. The reaction pathway and product formed were determined by analysis of the 13 C DEPT spectra. An octamer duplex, d(CGATTAGC·GCTAATCG), was synthesized and used in the interaction study of CC-1065 and the oligomer. The duplex and the drug-octamer complex were both analyzed by 2D spectroscopy (COSY, NOESY). The relative intensity of the NOEs observed between the drug (CC-1065) and the octamer duplex shows conclusively that the drug is located in the minor groove, covalently attached to N3 of adenine 6 and positioned from the 3' → 5' end in relation to strand A [d(CGATTA 6 GC)]. A mechanism for drug binding and stabilization can be inferred from the NOE data and model-building studies

  5. Exergic, economic and environmental impacts of natural gas and diesel in operation of combined cycle power plants

    International Nuclear Information System (INIS)

    Mohammadi Khoshkar Vandani, Amin; Joda, Fatemeh; Bozorgmehry Boozarjomehry, Ramin

    2016-01-01

    Highlights: • Investigating the effect of natural gas and diesel on the power plant performance. • Exergy, economic and environmental evaluation of a combined cycle power plant. • Using life cycle assessment (LCA) to perform the environmental evaluation. • Optimizing the power plant in terms of exergy and economic. • Better performance of natural gas with respect to diesel. - Abstract: Combined cycle power plants (CCPPs) play an important role in electricity production throughout the world. Their energy efficiency is relatively high and their production rates of greenhouse gases are considerably low. In a country like Iran with huge oil and gas resources, most CCPP’s use natural gas as primary fuel and diesel as secondary fuel. In this study, effect of using diesel instead of natural gas for a selected power plant will be investigated in terms of exergy, economic and environmental impacts. The environmental evaluation is performed using life cycle assessment (LCA). In the second step, the operation of the plant will be optimized using exergy and economic objective functions. The results show that the exergy efficiency of the plant with natural gas as fuel is equal to 43.11%, while this efficiency with diesel will be 42.03%. Furthermore, the annual cost of plant using diesel is twice as that of plant using natural gas. Finally, diesel utilization leads to more contaminants production. Thus, environmental effects of diesel are much higher than that of natural gas. The optimization results demonstrate that in case of natural gas, exergy efficiency and annual cost of the power plant improve 2.34% and 4.99%, respectively. While these improvements for diesel are 2.36% and 1.97%.

  6. Optoelectronic properties of CC2TA towards a good TADF material

    Science.gov (United States)

    Mishra, Ashok Kumar

    2018-05-01

    2,4-bis{f3-(9H-carbazol-9-yl)-9H-carbazol-9-yl}-6-phenyl-1,3,5-triazine (CC2TA) is a triazine derivatives in which the acceptor phenyltriazine unit is used as the central skeleton and donor bicarbazole units are bonded to both ends of the skeleton. Molecular orbital calculations exhibit that the HOMO and LUMO are locally allocated chiefly in the bicarbazole and phenyltriazine units, respectively. There are a class of organic molecules and polymers which exhibit semiconductor behavior because of nearly free conjugate π-electrons. Hopping of these electrons in molecules forms different excited singlet and triplet states named as excitons. Some of these organic molecules can be set to emit photons by triplet-singlet excitonic transition via a process called Thermally Activated Delayed Fluorescence (TADF) which is exploited for designing the Organic Light Emitting diode (OLED.) CC2TA is one of these reported noble metal-free TADF molecules which offers unique opto electronic properties arising from the reverse intersystem crossing between the lowest singlet (S) and triplet (T) excited states. Its ability to harvest triplet excitons for fluorescence through facilitated reverse intersystem crossing (T→S) could directly impact their properties and performances, which is attractive for a wide variety of low-cost optoelectronic device. In the present study, the CC2TA compounds have been taken up for the investigation of various optoelectronic properties including the thermally activated delayed fluorescence (TADF) by using the Koopmans Method and Density Functional Theory. The present study discusses the utility of the CC2TA organic semiconductor as a suitable TADF material essential for developing an efficient Organic Light Emitting Diode (OLED).

  7. Oral Presence of Carbohydrate and Caffeine in Chewing Gum: Independent and Combined Effects on Endurance Cycling Performance.

    Science.gov (United States)

    Oberlin-Brown, Katherine T; Siegel, Rodney; Kilding, Andrew E; Laursen, Paul B

    2016-03-01

    The oral presence of carbohydrate (CHO) and caffeine (CAF) may independently enhance exercise performance, but their influence on performance during prolonged exercise is less known. To determine the independent and combined effects of CHO and CAF administered in chewing gum during a cycling time trial (TT) after prolonged exercise. Eleven male cyclists (32.2 ± 7.5 y, 74.3 ± 6.8 kg, 60.2 ± 4.0 mL · kg-1 · min-1 VO2peak) performed 4 experimental trials consisting of 90-min constant-load cycling at 80% of their second ventilatory threshold (207 ± 30 W), followed immediately by a 20-km TT. Under double-blinded conditions, cyclists received placebo (PLA), CHO, CAF, or a combined CHO+CAF chewing gum at 0-, 5-, 10-, and 15-km points of the TT. Overall TT performance was similar across experimental and PLA trials (%mean difference ± 90%CL 0.2% ± 2.0%, 0.4% ± 2.2%, 0.1% ± 1.8% for CHO, CAF, and CHO+CAF). Compared with PLA, mean power output tended to be higher in the first 2 quarters of the TT with CHO (1.6% ± 3.1% and 0.8% ± 2.0%) and was substantially improved in the last 2 quarters during CAF and CHO+CAF trials (4.2% ± 3.0% and 2.0% ± 1.8%). There were no differences in average heart rate (ES performance. Blood lactate was substantially higher post-TT for CAF and CHO+CAF (ES >0.6). After prolonged constant-load cycling, the oral presence of CHO and CAF in chewing gum, independently or in combination, did not improve overall performance but did influence pacing.

  8. The epidermal cell kinetic response to ultraviolet B irradiation combines regenerative proliferation and carcinogen associated cell cycle delay

    Energy Technology Data Exchange (ETDEWEB)

    Olsen, W.M.; Kirkhus, B. (Oslo Univ. (Norway))

    1989-09-01

    The cell cycle traverse of epidermal basal cells 24 h after in vivo exposure of ultraviolet B (UVB) irradiation was studied by immunochemical staining of incorporated bromodeoxyuridine (BrdU) and bivariate BrdU/DNA flow cytometric analysis. The results were compared with the cell kinetic patterns following topical application of the skin carcinogen methylnitrosourea (MNU) as well as the skin irritant cantharidin. The cell cycle traverse in hairless mouse epidermis 24 h after in vivo exposure to UVB seemed to be a combination of the cell kinetic effects following chemical skin carcinogens and skin irritants. UVB irradiation induced both a delay in transit time through S phase, probably due to DNA damage and subsequent repair, as well as a reduction in the total cell cycle time consistent with rapid regenerative proliferation. (author).

  9. Rhenium-Promoted C-C Bond-Cleavage Reactions of Internal Propargyl Alcohols.

    Science.gov (United States)

    Lee, Kui Fun; Bai, Wei; Sung, Herman H Y; Williams, Ian D; Lin, Zhenyang; Jia, Guochen

    2018-06-07

    The first examples of C-C bond cleavage reactions of internal propargyl alcohols to give vinylidene complexes are described. Treatment of [Re(dppm) 3 ]I with RC≡CC(OH)R'R'' (R=aryl, alkyl; C(OH)R'R''=C(OH)Ph 2, C(OH)Me 2 , C(OH)HPh, C(OH)H 2 ) produced the vinylidene complexes ReI(=C=CHR)(dppm) 2 with the elimination of C(O)R'R''. Computational studies support that the reactions proceed through a β-alkynyl elimination of alkoxide intermediates Re{OC(R')(R'')C≡CR}(dppm) 2 . © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  10. Potential Hazards Relating to Pyrolysis of c-C4F8O, n-C4F10 and c-C4F8 in selected gaseous diffusion plant operations

    International Nuclear Information System (INIS)

    Trowbridge, L.D.

    2000-01-01

    As part of a program intended to replace the present evaporative coolant at the gaseous diffusion plants (GDPs) with a non-ozone-depleting alternate, a series of investigations of the suitability of candidate substitutes is under way. This report summarizes studies directed at estimating the chemical and thermal stability of three candidate coolants, c-C 4 F 8 O, n-C 4 F 10 and c-C 4 4F 8 , in a few specific environments to be found in gaseous diffusion plant operations

  11. Effect of Curing Conditions and Freeze-Thaw Cycles on the Strength of an Expansive Soil Stabilized with a Combination of Lime, Jaggery, and Gallnut Powder

    Directory of Open Access Journals (Sweden)

    Jijo James

    2018-01-01

    Full Text Available This investigation involved the utilization of the combination of lime, jaggery, and gallnut powder, adopted in South India traditionally. This combination of materials, used for the manufacture of lime-based mortars, was adopted in stabilization of an expansive soil. Three combinations of lime, jaggery, and gallnut powder (LJG in the ratios of 8 : 2 : 2, 8 : 2 : 1, and 8 : 1 : 2 were put into use. The effect of subjecting the combinations to alternate cycles of freeze-thaw (up to 3 cycles and three different curing conditions of air, moisture, and heat was also investigated. In addition, a mineralogical investigation for studying the reaction products was also carried out. The investigation proceeded with the determination of the unconfined compression strength (UCS of stabilized specimens of dimensions 38 mm × 76 mm, cured for periods of 3, 7, 14, and 28 days. The results of the investigation revealed that the addition of LJG resulted in an increase in the strength of the stabilized soil. Freeze-thaw cycles resulted in a reduction in strength with LJG821 proving to be the most optimal combination developing the maximum strength and least strength loss due to freeze-thaw cycles. Thermal curing proved to be the most optimal curing condition out of all curing conditions evaluated.

  12. Tunisia- British gas intends to participate to the building of a combined cycle electric power plant

    International Nuclear Information System (INIS)

    Anon.

    1996-01-01

    Here is described the project to build a combined-cycle power plant in Tunisia, project in which the British Gas is interested. The transport, distribution, import and export of electricity should be controlled by the Tunisian society of electricity and gas. In the context of an agreement with Gec-Alsthom, the british company hopes to offer to build, and exploit the future power plant. (N.C.)

  13. The role of metformin in ovulation induction: Current status

    Directory of Open Access Journals (Sweden)

    Aboubakr Mohamed Elnashar

    2011-09-01

    Full Text Available To define the exact role of metformin in ovulation induction, it is crucial to distinguish three different indications: naïve PCOS, CC-resistant PCOS and ART. In naïve PCOS: metformin as compared to placebo has been shown to improve ovulation rates, but metformin did not exert significant advantage over CC with respect to cumulative ovulation, pregnancy or live-birth rates. The combined approach of metformin plus CC is not better than CC or metformin monotherapy in naïve PCOS. In CC-resistant patients: metformin has no benefit over placebo in ovulation, pregnancy, and live-birth rates as a single agent, but the combination of metformin and CC significantly improved ovulation and pregnancy rates when compared with CC alone. However, combined therapy did not improve the odds of live birth. Metformin pretreatment improves the efficacy of CC in PCOS patients with CC resistance. In PCOS patients scheduled for ART: metformin addition to gonadotropins reduces the duration of gonadotropins administration and the doses of gonadotropins required, and increases the rate of monoovulations, reducing the risk of cancelled cycles. Metformin co-administration to IVF treatment does not improve pregnancy or live-birth rates but reduces the risk of OHSS.

  14. Clomiphene Citrate Treatment Cycle Outcomes of Polycystic Ovary Syndrome Patients Based on Basal High Sensitive C-Reactive Protein Levels: A Cross-Sectional Study

    Directory of Open Access Journals (Sweden)

    Serkan Kahyaoglu

    2016-11-01

    Full Text Available Background: Polycystic ovary syndrome (PCOS is highly associated with an ovulatory infertility, features of the metabolic syndrome, including obesity, insulin resistance and dyslipidemia. Serum concentrations of high sensitive C-reactive protein (hs-CRP were significantly higher in obese than in non-obese PCOS patients at baseline, suggesting a relationship between elevated hs-CRP levels and obesity. The aim of this study was to evaluate whether cycle day 3 hs-CRP levels before clomiphene citrate (CC treatment would predict cycle outcomes in women with PCOS. Materials and Methods: This cross-sectional study was conducted among 84 infertile women with PCOS who were treated with CC at Zekai Tahir Burak Women’s Health Education and Research Hospital, Ankara, Turkey, between January 2014 and January 2015. Based on the exclusion criteria, cycle outcomes of remaining 66 infertile women with PCOS treated with CC were analyzed. The hs-CRP levels and insulin resistance indexes were evaluated on day 3 of the CC treatment cycle. The primary outcome measures were number of preovulatory follicles measuring≥17 mm and pregnancy rates. Results: The mean ± SD age of the patients was 24.0 ± 3.8 years (range 18-36. The mean ± SD body mass index (BMI of the patients was 25.7 ± 4.9 (range 17-43. Fifty patients developed dominant follicle (75% and 5 patients established clinical pregnancy during the study (clinical pregnancy rate: 7%. The mean ± SD baseline hs-CRP, fasting insulin and Homeostasis Model Assessment-Insulin Resistance (HOMA-IR values of the patients with and without dominant follicle generation during treatment cycle were 6.42 ± 7.05 and 4.41 ± 2.95 (P=0.27, 11.61 ± 6.94 and 10.95 ± 5.65 (P=0.73, 2.68 ± 1.79 and 2.41 ± 1.30 (P=0.58, respectively. The mean ± SD baseline hs-CRP, fasting insulin and HOMA-IR values of the patients with and without clinical pregnancy establishment following treatment cycle were 6.30 ± 2.56 and 5.90 ± 6

  15. Pressurized fluidized bed combustion combined cycle power plant with coal gasification: Second generation pilot plant

    International Nuclear Information System (INIS)

    Farina, G.L.; Bressan, L.

    1991-01-01

    This paper presents the technical and economical background of a research and development program of a novel power generation scheme, which is based on coal gasification, pressurized fluid bed combustion and combined cycles. The participants in this program are: Foster Wheeler (project leader), Westinghouse, IGT and the USA Dept. of Energy. The paper describes the characteristics of the plant, the research program in course of implementation, the components of the pilot plant and the first results obtained

  16. Recognition and repair of the CC-1065-(N3-Adenine)-DNA adduct by the UVRABC nuclease

    International Nuclear Information System (INIS)

    Tang, M.; Lee, C.S.; Doisy, R.; Ross, L.; Needham-VanDevanter, D.R.; Hurley, L.H.

    1988-01-01

    The recognition and repair of the helix-stabilizing and relatively nondistortive CC-1065-(N3-adenine)-DNA adduct by UVRABC nuclease has been investigated both in vivo with phi X174RFI DNA by a transfection assay and in vitro by a site-directed adduct in a 117 base pair fragment from M13mp1. CC-1065 is a potent antitumor antibiotic produced by Streptomyces zelensis which binds within the minor groove of DNA through N3 of adenine. In contrast to the helix-destabilizing and distortive modifications of DNA caused by ultraviolet light or N-acetoxy-2-(acetylamino)fluorene, CC-1065 increases the melting point of DNA and decreases the S1 nuclease activity. Using a viral DNA-Escherichia coli transfection system, the authors have found that the uvrA, uvrB, and uvrC genes, which code for the major excision repair proteins for UV- and NAAAF-induced DNA damage, are also involved in the repair of CC-1065-DNA adducts. In contrast, the uvrD gene product, which has been found to be involved in the repair of UV damage, has no effect in repairing CC-1065-DNA adducts. Purified UVRA, UVRB, and UVRC proteins must work in concert to incise the drug-modified phi X174RFI DNA. Using a site-directed and multiple CC-1065 modified (MspI-BstNI) 117 base pair fragment from M13mp1, they have found that UVRABC nuclease incises at the eight phosphodiester bond on the 5' side of the CC-1065-DNA adduct on the drug-modified strand. The enzymes do not cut the noncovalently modified strand. The DNA sequence and/or helix-stabilizing effect of multiple adducts may determine the recognition and/or incision of the drug-DNA adduct by UVRABC nuclease. These results are discussed in relation to the structure of the CC-1065-DNA adduct and the effect of drug binding on local DNA structure

  17. First measurement of the lifetime of the doubly charmed baryon $\\Xi_{cc}^{++}$

    CERN Document Server

    Aaij, Roel; LHCb Collaboration; Adinolfi, Marco; Aidala, Christine Angela; Ajaltouni, Ziad; Akar, Simon; Albicocco, Pietro; Albrecht, Johannes; Alessio, Federico; Alexander, Michael; Alfonso Albero, Alejandro; Ali, Suvayu; Alkhazov, Georgy; Alvarez Cartelle, Paula; Alves Jr, Antonio Augusto; Amato, Sandra; Amerio, Silvia; Amhis, Yasmine; An, Liupan; Anderlini, Lucio; Andreassi, Guido; Andreotti, Mirco; Andrews, Jason; Appleby, Robert; Archilli, Flavio; d'Argent, Philippe; Arnau Romeu, Joan; Artamonov, Alexander; Artuso, Marina; Arzymatov, Kenenbek; Aslanides, Elie; Atzeni, Michele; Audurier, Benjamin; Bachmann, Sebastian; Back, John; Baker, Sophie; Balagura, Vladislav; Baldini, Wander; Baranov, Alexander; Barlow, Roger; Barsuk, Sergey; Barter, William; Baryshnikov, Fedor; Batozskaya, Varvara; Batsukh, Baasansuren; Battista, Vincenzo; Bay, Aurelio; Beddow, John; Bedeschi, Franco; Bediaga, Ignacio; Beiter, Andrew; Bel, Lennaert; Beliy, Nikita; Bellee, Violaine; Belloli, Nicoletta; Belous, Konstantin; Belyaev, Ivan; Ben-Haim, Eli; Bencivenni, Giovanni; Benson, Sean; Beranek, Sarah; Berezhnoy, Alexander; Bernet, Roland; Berninghoff, Daniel; Bertholet, Emilie; Bertolin, Alessandro; Betancourt, Christopher; Betti, Federico; Bettler, Marc-Olivier; van Beuzekom, Martinus; Bezshyiko, Iaroslava; Bhasin, Srishti; Bhom, Jihyun; Bian, Lingzhu; Bifani, Simone; Billoir, Pierre; Birnkraut, Alex; Bizzeti, Andrea; Bjørn, Mikkel; Blago, Michele Piero; Blake, Thomas; Blanc, Frederic; Blusk, Steven; Bobulska, Dana; Bocci, Valerio; Boente Garcia, Oscar; Boettcher, Thomas; Bondar, Alexander; Bondar, Nikolay; Borghi, Silvia; Borisyak, Maxim; Borsato, Martino; Bossu, Francesco; Boubdir, Meriem; Bowcock, Themistocles; Bozzi, Concezio; Braun, Svende; Brodski, Michael; Brodzicka, Jolanta; Brossa Gonzalo, Arnau; Brundu, Davide; Buchanan, Emma; Buonaura, Annarita; Burr, Christopher; Bursche, Albert; Buytaert, Jan; Byczynski, Wiktor; Cadeddu, Sandro; Cai, Hao; Calabrese, Roberto; Calladine, Ryan; Calvi, Marta; Calvo Gomez, Miriam; Camboni, Alessandro; Campana, Pierluigi; Campora Perez, Daniel Hugo; Capriotti, Lorenzo; Carbone, Angelo; Carboni, Giovanni; Cardinale, Roberta; Cardini, Alessandro; Carniti, Paolo; Carson, Laurence; Carvalho Akiba, Kazuyoshi; Casse, Gianluigi; Cassina, Lorenzo; Cattaneo, Marco; Cavallero, Giovanni; Cenci, Riccardo; Chamont, David; Chapman, Matthew George; Charles, Matthew; Charpentier, Philippe; Chatzikonstantinidis, Georgios; Chefdeville, Maximilien; Chekalina, Viktoriia; Chen, Chen; Chen, Shanzhen; Chitic, Stefan-Gabriel; Chobanova, Veronika; Chrzaszcz, Marcin; Chubykin, Alexsei; Ciambrone, Paolo; Cid Vidal, Xabier; Ciezarek, Gregory; Clarke, Peter; Clemencic, Marco; Cliff, Harry; Closier, Joel; Coco, Victor; Coelho, Joao A B; Cogan, Julien; Cogneras, Eric; Cojocariu, Lucian; Collins, Paula; Colombo, Tommaso; Comerma-Montells, Albert; Contu, Andrea; Coombs, George; Coquereau, Samuel; Corti, Gloria; Corvo, Marco; Costa Sobral, Cayo Mar; Couturier, Benjamin; Cowan, Greig; Craik, Daniel Charles; Crocombe, Andrew; Cruz Torres, Melissa Maria; Currie, Robert; D'Ambrosio, Carmelo; Da Cunha Marinho, Franciole; Da Silva, Cesar Luiz; Dall'Occo, Elena; Dalseno, Jeremy; Danilina, Anna; Davis, Adam; De Aguiar Francisco, Oscar; De Bruyn, Kristof; De Capua, Stefano; De Cian, Michel; De Miranda, Jussara; De Paula, Leandro; De Serio, Marilisa; De Simone, Patrizia; Dean, Cameron Thomas; Decamp, Daniel; Del Buono, Luigi; Delaney, Blaise; Dembinski, Hans Peter; Demmer, Moritz; Dendek, Adam; Derkach, Denis; Deschamps, Olivier; Desse, Fabrice; Dettori, Francesco; Dey, Biplab; Di Canto, Angelo; Di Nezza, Pasquale; Didenko, Sergey; Dijkstra, Hans; Dordei, Francesca; Dorigo, Mirco; Dosil Suárez, Alvaro; Douglas, Lauren; Dovbnya, Anatoliy; Dreimanis, Karlis; Dufour, Laurent; Dujany, Giulio; Durante, Paolo; Durham, John Matthew; Dutta, Deepanwita; Dzhelyadin, Rustem; Dziewiecki, Michal; Dziurda, Agnieszka; Dzyuba, Alexey; Easo, Sajan; Egede, Ulrik; Egorychev, Victor; Eidelman, Semen; Eisenhardt, Stephan; Eitschberger, Ulrich; Ekelhof, Robert; Eklund, Lars; Ely, Scott; Ene, Alexandru; Escher, Stephan; Esen, Sevda; Evans, Timothy; Falabella, Antonio; Farley, Nathanael; Farry, Stephen; Fazzini, Davide; Federici, Luca; Fernandez Declara, Placido; Fernandez Prieto, Antonio; Ferrari, Fabio; Ferreira Lopes, Lino; Ferreira Rodrigues, Fernando; Ferro-Luzzi, Massimiliano; Filippov, Sergey; Fini, Rosa Anna; Fiorini, Massimiliano; Firlej, Miroslaw; Fitzpatrick, Conor; Fiutowski, Tomasz; Fleuret, Frederic; Fontana, Marianna; Fontanelli, Flavio; Forty, Roger; Franco Lima, Vinicius; Frank, Markus; Frei, Christoph; Fu, Jinlin; Funk, Wolfgang; Färber, Christian; Féo Pereira Rivello Carvalho, Mauricio; Gabriel, Emmy; Gallas Torreira, Abraham; Galli, Domenico; Gallorini, Stefano; Gambetta, Silvia; Gan, Yuyue; Gandelman, Miriam; Gandini, Paolo; Gao, Yuanning; Garcia Martin, Luis Miguel; Garcia Plana, Beatriz; García Pardiñas, Julián; Garra Tico, Jordi; Garrido, Lluis; Gascon, David; Gaspar, Clara; Gavardi, Laura; Gazzoni, Giulio; Gerick, David; Gersabeck, Evelina; Gersabeck, Marco; Gershon, Timothy; Gerstel, Dawid; Ghez, Philippe; Gianì, Sebastiana; Gibson, Valerie; Girard, Olivier Göran; Giubega, Lavinia-Helena; Gizdov, Konstantin; Gligorov, Vladimir; Golubkov, Dmitry; Golutvin, Andrey; Gomes, Alvaro; Gorelov, Igor Vladimirovich; Gotti, Claudio; Govorkova, Ekaterina; Grabowski, Jascha Peter; Graciani Diaz, Ricardo; Granado Cardoso, Luis Alberto; Graugés, Eugeni; Graverini, Elena; Graziani, Giacomo; Grecu, Alexandru; Greim, Roman; Griffith, Peter; Grillo, Lucia; Gruber, Lukas; Gruberg Cazon, Barak Raimond; Grünberg, Oliver; Gu, Chenxi; Gushchin, Evgeny; Guz, Yury; Gys, Thierry; Göbel, Carla; Hadavizadeh, Thomas; Hadjivasiliou, Christos; Haefeli, Guido; Haen, Christophe; Haines, Susan; Hamilton, Brian; Han, Xiaoxue; Hancock, Thomas Henry; Hansmann-Menzemer, Stephanie; Harnew, Neville; Harnew, Samuel; Harrison, Thomas; Hasse, Christoph; Hatch, Mark; He, Jibo; Hecker, Malte; Heinicke, Kevin; Heister, Arno; Hennessy, Karol; Henry, Louis; van Herwijnen, Eric; Heß, Miriam; Hicheur, Adlène; Hidalgo Charman, Raoul; Hill, Donal; Hilton, Martha; Hopchev, Plamen Hristov; Hu, Wenhua; Huang, Wenqian; Huard, Zachary; Hulsbergen, Wouter; Humair, Thibaud; Hushchyn, Mikhail; Hutchcroft, David; Hynds, Daniel; Ibis, Philipp; Idzik, Marek; Ilten, Philip; Ivshin, Kuzma; Jacobsson, Richard; Jalocha, Pawel; Jans, Eddy; Jawahery, Abolhassan; Jiang, Feng; John, Malcolm; Johnson, Daniel; Jones, Christopher; Joram, Christian; Jost, Beat; Jurik, Nathan; Kandybei, Sergii; Karacson, Matthias; Kariuki, James Mwangi; Karodia, Sarah; Kazeev, Nikita; Kecke, Matthieu; Keizer, Floris; Kelsey, Matthew; Kenzie, Matthew; Ketel, Tjeerd; Khairullin, Egor; Khanji, Basem; Khurewathanakul, Chitsanu; Kim, Kyung Eun; Kirn, Thomas; Klaver, Suzanne; Klimaszewski, Konrad; Klimkovich, Tatsiana; Koliiev, Serhii; Kolpin, Michael; Kopecna, Renata; Koppenburg, Patrick; Kostiuk, Igor; Kotriakhova, Sofia; Kozeiha, Mohamad; Kravchuk, Leonid; Kreps, Michal; Kress, Felix Johannes; Krokovny, Pavel; Krupa, Wojciech; Krzemien, Wojciech; Kucewicz, Wojciech; Kucharczyk, Marcin; Kudryavtsev, Vasily; Kuonen, Axel Kevin; Kvaratskheliya, Tengiz; Lacarrere, Daniel; Lafferty, George; Lai, Adriano; Lancierini, Davide; Lanfranchi, Gaia; Langenbruch, Christoph; Latham, Thomas; Lazzeroni, Cristina; Le Gac, Renaud; Leflat, Alexander; Lefrançois, Jacques; Lefèvre, Regis; Lemaitre, Florian; Leroy, Olivier; Lesiak, Tadeusz; Leverington, Blake; Li, Pei-Rong; Li, Tenglin; Li, Zhuoming; Liang, Xixin; Likhomanenko, Tatiana; Lindner, Rolf; Lionetto, Federica; Lisovskyi, Vitalii; Liu, Xuesong; Loh, David; Loi, Angelo; Longstaff, Iain; Lopes, Jose; Lovell, George Holger; Lucchesi, Donatella; Lucio Martinez, Miriam; Lupato, Anna; Luppi, Eleonora; Lupton, Oliver; Lusiani, Alberto; Lyu, Xiao-Rui; Machefert, Frederic; Maciuc, Florin; Macko, Vladimir; Mackowiak, Patrick; Maddrell-Mander, Samuel; Maev, Oleg; Maguire, Kevin; Maisuzenko, Dmitrii; Majewski, Maciej Witold; Malde, Sneha; Malecki, Bartosz; Malinin, Alexander; Maltsev, Timofei; Manca, Giulia; Mancinelli, Giampiero; Marangotto, Daniele; Maratas, Jan; Marchand, Jean François; Marconi, Umberto; Marin Benito, Carla; Marinangeli, Matthieu; Marino, Pietro; Marks, Jörg; Marshall, Phillip John; Martellotti, Giuseppe; Martin, Morgan; Martinelli, Maurizio; Martinez Santos, Diego; Martinez Vidal, Fernando; Massafferri, André; Materok, Marcel; Matev, Rosen; Mathad, Abhijit; Mathe, Zoltan; Matteuzzi, Clara; Mauri, Andrea; Maurice, Emilie; Maurin, Brice; Mazurov, Alexander; McCann, Michael; McNab, Andrew; McNulty, Ronan; Mead, James Vincent; Meadows, Brian; Meaux, Cedric; Meier, Frank; Meinert, Nis; Melnychuk, Dmytro; Merk, Marcel; Merli, Andrea; Michielin, Emanuele; Milanes, Diego Alejandro; Millard, Edward James; Minard, Marie-Noelle; Minzoni, Luca; Mitzel, Dominik Stefan; Mogini, Andrea; Molina Rodriguez, Josue; Mombächer, Titus; Monroy, Igancio Alberto; Monteil, Stephane; Morandin, Mauro; Morello, Gianfranco; Morello, Michael Joseph; Morgunova, Olga; Moron, Jakub; Morris, Adam Benjamin; Mountain, Raymond; Muheim, Franz; Mulder, Mick; Murphy, Colm Harold; Murray, Donal; Mödden, Antje; Müller, Dominik; Müller, Janine; Müller, Katharina; Müller, Vanessa; Naik, Paras; Nakada, Tatsuya; Nandakumar, Raja; Nandi, Anita; Nanut, Tara; Nasteva, Irina; Needham, Matthew; Neri, Nicola; Neubert, Sebastian; Neufeld, Niko; Neuner, Max; Nguyen, Thi Dung; Nguyen-Mau, Chung; Nieswand, Simon; Niet, Ramon; Nikitin, Nikolay; Nogay, Alla; O'Hanlon, Daniel Patrick; Oblakowska-Mucha, Agnieszka; Obraztsov, Vladimir; Ogilvy, Stephen; Oldeman, Rudolf; Onderwater, Gerco; Ossowska, Anna; Otalora Goicochea, Juan Martin; Owen, Patrick; Oyanguren, Maria Aranzazu; Pais, Preema Rennee; Pajero, Tommaso; Palano, Antimo; Palutan, Matteo; Panshin, Gennady; Papanestis, Antonios; Pappagallo, Marco; Pappalardo, Luciano; Parker, William; Parkes, Christopher; Passaleva, Giovanni; Pastore, Alessandra; Patel, Mitesh; Patrignani, Claudia; Pearce, Alex; Pellegrino, Antonio; Penso, Gianni; Pepe Altarelli, Monica; Perazzini, Stefano; Pereima, Dmitrii; Perret, Pascal; Pescatore, Luca; Petridis, Konstantinos; Petrolini, Alessandro; Petrov, Aleksandr; Petrucci, Stefano; Petruzzo, Marco; Pietrzyk, Boleslaw; Pietrzyk, Guillaume; Pikies, Malgorzata; Pili, Martina; Pinci, Davide; Pinzino, Jacopo; Pisani, Flavio; Piucci, Alessio; Placinta, Vlad-Mihai; Playfer, Stephen; Plews, Jonathan; Plo Casasus, Maximo; Polci, Francesco; Poli Lener, Marco; Poluektov, Anton; Polukhina, Natalia; Polyakov, Ivan; Polycarpo, Erica; Pomery, Gabriela Johanna; Ponce, Sebastien; Popov, Alexander; Popov, Dmitry; Poslavskii, Stanislav; Potterat, Cédric; Price, Eugenia; Prisciandaro, Jessica; Prouve, Claire; Pugatch, Valery; Puig Navarro, Albert; Pullen, Hannah Louise; Punzi, Giovanni; Qian, Wenbin; Qin, Jia-Jia; Quagliani, Renato; Quintana, Boris; Rachwal, Bartlomiej; Rademacker, Jonas; Rama, Matteo; Ramos Pernas, Miguel; Rangel, Murilo; Ratnikov, Fedor; Raven, Gerhard; Ravonel Salzgeber, Melody; Reboud, Meril; Redi, Federico; Reichert, Stefanie; dos Reis, Alberto; Reiss, Florian; Remon Alepuz, Clara; Ren, Zan; Renaudin, Victor; Ricciardi, Stefania; Richards, Sophie; Rinnert, Kurt; Robbe, Patrick; Robert, Arnaud; Rodrigues, Ana Barbara; Rodrigues, Eduardo; Rodriguez Lopez, Jairo Alexis; Roehrken, Markus; Rogozhnikov, Alexey; Roiser, Stefan; Rollings, Alexandra Paige; Romanovskiy, Vladimir; Romero Vidal, Antonio; Rotondo, Marcello; Rudolph, Matthew Scott; Ruf, Thomas; Ruiz Vidal, Joan; Saborido Silva, Juan Jose; Sagidova, Naylya; Saitta, Biagio; Salustino Guimaraes, Valdir; Sanchez Gras, Cristina; Sanchez Mayordomo, Carlos; Sanmartin Sedes, Brais; Santacesaria, Roberta; Santamarina Rios, Cibran; Santimaria, Marco; Santovetti, Emanuele; Sarpis, Gediminas; Sarti, Alessio; Satriano, Celestina; Satta, Alessia; Saur, Miroslav; Savrina, Darya; Schael, Stefan; Schellenberg, Margarete; Schiller, Manuel; Schindler, Heinrich; Schmelling, Michael; Schmelzer, Timon; Schmidt, Burkhard; Schneider, Olivier; Schopper, Andreas; Schreiner, HF; Schubiger, Maxime; Schune, Marie Helene; Schwemmer, Rainer; Sciascia, Barbara; Sciubba, Adalberto; Semennikov, Alexander; Sepulveda, Eduardo Enrique; Sergi, Antonino; Serra, Nicola; Serrano, Justine; Sestini, Lorenzo; Seuthe, Alex; Seyfert, Paul; Shapkin, Mikhail; Shcheglov, Yury; Shears, Tara; Shekhtman, Lev; Shevchenko, Vladimir; Shmanin, Evgenii; Siddi, Benedetto Gianluca; Silva Coutinho, Rafael; Silva de Oliveira, Luiz Gustavo; Simi, Gabriele; Simone, Saverio; Skidmore, Nicola; Skwarnicki, Tomasz; Smeaton, John Gordon; Smith, Eluned; Smith, Iwan Thomas; Smith, Mark; Soares, Marcelo; Soares Lavra, Lais; Sokoloff, Michael; Soler, Paul; Souza De Paula, Bruno; Spaan, Bernhard; Spradlin, Patrick; Stagni, Federico; Stahl, Marian; Stahl, Sascha; Stefko, Pavol; Stefkova, Slavomira; Steinkamp, Olaf; Stemmle, Simon; Stenyakin, Oleg; Stepanova, Margarita; Stevens, Holger; Stone, Sheldon; Storaci, Barbara; Stracka, Simone; Stramaglia, Maria Elena; Straticiuc, Mihai; Straumann, Ulrich; Strokov, Sergey; Sun, Jiayin; Sun, Liang; Swientek, Krzysztof; Syropoulos, Vasileios; Szumlak, Tomasz; Szymanski, Maciej Pawel; T'Jampens, Stephane; Tang, Zhipeng; Tayduganov, Andrey; Tekampe, Tobias; Tellarini, Giulia; Teubert, Frederic; Thomas, Eric; van Tilburg, Jeroen; Tilley, Matthew James; Tisserand, Vincent; Tolk, Siim; Tomassetti, Luca; Tonelli, Diego; Tou, Da Yu; Tourinho Jadallah Aoude, Rafael; Tournefier, Edwige; Traill, Murdo; Tran, Minh Tâm; Trisovic, Ana; Tsaregorodtsev, Andrei; Tuci, Giulia; Tully, Alison; Tuning, Niels; Ukleja, Artur; Usachov, Andrii; Ustyuzhanin, Andrey; Uwer, Ulrich; Vacca, Claudia; Vagner, Alexander; Vagnoni, Vincenzo; Valassi, Andrea; Valat, Sebastien; Valenti, Giovanni; Vazquez Gomez, Ricardo; Vazquez Regueiro, Pablo; Vecchi, Stefania; van Veghel, Maarten; Velthuis, Jaap; Veltri, Michele; Veneziano, Giovanni; Venkateswaran, Aravindhan; Verlage, Tobias Anton; Vernet, Maxime; Veronesi, Michele; Veronika, Naomi; Vesterinen, Mika; Viana Barbosa, Joao Vitor; Vieira, Daniel; Vieites Diaz, Maria; Viemann, Harald; Vilasis-Cardona, Xavier; Vitkovskiy, Arseniy; Vitti, Marcela; Volkov, Vladimir; Vollhardt, Achim; Voneki, Balazs; Vorobyev, Alexey; Vorobyev, Vitaly; de Vries, Jacco; Vázquez Sierra, Carlos; Waldi, Roland; Walsh, John; Wang, Jianchun; Wang, Mengzhen; Wang, Yilong; Wang, Zhenzi; Ward, David; Wark, Heather Mckenzie; Watson, Nigel; Websdale, David; Weiden, Andreas; Weisser, Constantin; Whitehead, Mark; Wicht, Jean; Wilkinson, Guy; Wilkinson, Michael; Williams, Ifan; Williams, Mark Richard James; Williams, Mike; Williams, Timothy; Wilson, Fergus; Wimberley, Jack; Winn, Michael Andreas; Wishahi, Julian; Wislicki, Wojciech; Witek, Mariusz; Wormser, Guy; Wotton, Stephen; Wyllie, Kenneth; Xiao, Dong; Xie, Yuehong; Xu, Ao; Xu, Menglin; Xu, Qingnian; Xu, Zehua; Xu, Zhirui; Yang, Zhenwei; Yang, Zishuo; Yao, Yuezhe; Yeomans, Lauren Emma; Yin, Hang; Yu, Jiesheng; Yuan, Xuhao; Yushchenko, Oleg; Zarebski, Kristian Alexander; Zavertyaev, Mikhail; Zhang, Dongliang; Zhang, Liming; Zhang, Wen Chao; Zhang, Yanxi; Zhelezov, Alexey; Zheng, Yangheng; Zhu, Xianglei; Zhukov, Valery; Zonneveld, Jennifer Brigitta; Zucchelli, Stefano

    2018-01-01

    The first measurement of the lifetime of the doubly charmed baryon $\\Xi_{cc}^{++}$ is presented, with the signal reconstructed in the final state $\\Lambda_c^+ K^- \\pi^+ \\pi^+$. The data sample used corresponds to an integrated luminosity of $1.7\\,\\mathrm{fb}^{-1}$, collected by the LHCb experiment in proton-proton collisions at a centre-of-mass energy of $13\\mathrm{\\,Te\\kern -0.1em V}$. The $\\Xi_{cc}^{++}$ lifetime is measured to be $0.256\\,^{+0.024}_{-0.022}{\\,\\rm (stat)\\,} \\pm 0.014 {\\,\\rm(syst)}\\mathrm{\\,ps}$.

  18. Genotypic and Phenotypic Markers of Livestock-Associated Methicillin-Resistant Staphylococcus aureus CC9 in Humans.

    Science.gov (United States)

    Ye, Xiaohua; Wang, Xiaolin; Fan, Yanping; Peng, Yang; Li, Ling; Li, Shunming; Huang, Jingya; Yao, Zhenjiang; Chen, Sidong

    2016-07-01

    Use of antimicrobials in industrial food animal production is associated with the presence of multidrug-resistant Staphylococcus aureus among animals and humans. The livestock-associated (LA) methicillin-resistant S. aureus (MRSA) clonal complex 9 (CC9) is associated with animals and related workers in Asia. This study aimed to explore the genotypic and phenotypic markers of LA-MRSA CC9 in humans. We conducted a cross-sectional study of livestock workers and controls in Guangdong, China. The study participants responded to a questionnaire and provided a nasal swab for S. aureus analysis. The resulting isolates were assessed for antibiotic susceptibility, multilocus sequence type, and immune evasion cluster (IEC) genes. Livestock workers had significantly higher rates of S. aureus CC9 (odds ratio [OR] = 30.98; 95% confidence interval [CI], 4.06 to 236.39) and tetracycline-resistant S. aureus (OR = 3.26; 95% CI, 2.12 to 5.00) carriage than controls. All 19 S. aureus CC9 isolates from livestock workers were MRSA isolates and also exhibited the characteristics of resistance to several classes of antibiotics and absence of the IEC genes. Notably, the interaction analyses indicated phenotype-phenotype (OR = 525.7; 95% CI, 60.0 to 4,602.1) and gene-environment (OR = 232.3; 95% CI, 28.7 to 1,876.7) interactions associated with increased risk for livestock-associated S. aureus CC9 carriage. These findings suggest that livestock-associated S. aureus and MRSA (CC9, IEC negative, and tetracycline resistant) in humans are associated with occupational livestock contact, raising questions about the potential for occupational exposure to opportunistic S. aureus This study adds to existing knowledge by giving insight into the genotypic and phenotypic markers of LA-MRSA. Our findings suggest that livestock-associated S. aureus and MRSA (CC9, IEC negative, and tetracycline resistant) in humans are associated with occupational livestock contact. Future studies should direct more

  19. Use of the 5E learning cycle model combined with problem-based learning for a fundamentals of nursing course.

    Science.gov (United States)

    Jun, Won Hee; Lee, Eun Ju; Park, Han Jong; Chang, Ae Kyung; Kim, Mi Ja

    2013-12-01

    The 5E learning cycle model has shown a positive effect on student learning in science education, particularly in courses with theory and practice components. Combining problem-based learning (PBL) with the 5E learning cycle was suggested as a better option for students' learning of theory and practice. The purpose of this study was to compare the effects of the traditional learning method with the 5E learning cycle model with PBL. The control group (n = 78) was subjected to a learning method that consisted of lecture and practice. The experimental group (n = 83) learned by using the 5E learning cycle model with PBL. The results showed that the experimental group had significantly improved self-efficacy, critical thinking, learning attitude, and learning satisfaction. Such an approach could be used in other countries to enhance students' learning of fundamental nursing. Copyright 2013, SLACK Incorporated.

  20. Outcome of the TURP-TUVP sandwich procedure for minimally invasive surgical treatment of benign prostatic hyperplasia with volume larger than 40cc over a 4-year period in Nigeria

    Directory of Open Access Journals (Sweden)

    O.I. Aisuodionoe-Shadrach

    2013-03-01

    Conclusions: The sandwich combination of TURP and TUVP for the surgical treatment of BPH with volume larger than 40cc had satisfactory patient safety profile and resulted in significant improvement in IPSS, Qmax and PVR on follow-up at 3 months.

  1. Exergy, exergoeconomic and environmental analyses and evolutionary algorithm based multi-objective optimization of combined cycle power plants

    International Nuclear Information System (INIS)

    Ahmadi, Pouria; Dincer, Ibrahim; Rosen, Marc A.

    2011-01-01

    A comprehensive exergy, exergoeconomic and environmental impact analysis and optimization is reported of several combined cycle power plants (CCPPs). In the first part, thermodynamic analyses based on energy and exergy of the CCPPs are performed, and the effect of supplementary firing on the natural gas-fired CCPP is investigated. The latter step includes the effect of supplementary firing on the performance of bottoming cycle and CO 2 emissions, and utilizes the first and second laws of thermodynamics. In the second part, a multi-objective optimization is performed to determine the 'best' design parameters, accounting for exergetic, economic and environmental factors. The optimization considers three objective functions: CCPP exergy efficiency, total cost rate of the system products and CO 2 emissions of the overall plant. The environmental impact in terms of CO 2 emissions is integrated with the exergoeconomic objective function as a new objective function. The results of both exergy and exergoeconomic analyses show that the largest exergy destructions occur in the CCPP combustion chamber, and that increasing the gas turbine inlet temperature decreases the CCPP cost of exergy destruction. The optimization results demonstrates that CO 2 emissions are reduced by selecting the best components and using a low fuel injection rate into the combustion chamber. -- Highlights: → Comprehensive thermodynamic modeling of a combined cycle power plant. → Exergy, economic and environmental analyses of the system. → Investigation of the role of multiobjective exergoenvironmental optimization as a tool for more environmentally-benign design.

  2. Study on thermodynamic cycle of high temperature gas-cooled reactor

    International Nuclear Information System (INIS)

    Qu Xinhe; Yang Xiaoyong; Wang Jie

    2017-01-01

    The development trend of the (very) High temperature gas-cooled reactor is to gradually increase the reactor outlet temperature. The different power conversion units are required at the different reactor outlet temperature. In this paper, for the helium turbine direct cycle and the combined cycle of the power conversion unit of the High temperature gas-cooled reactor, the mathematic models are established, and three cycle plans are designed. The helium turbine direct cycle is a Brayton cycle with recuperator, precooler and intercooler. In the combined cycle plan 1, the topping cycle is a simple Brayton cycle without recuperator, precooler and intercooler, and the bottoming cycle is based on the steam parameters (540deg, 6 MPa) recommended by Siemens. In the combined cycle plan 2, the topping cycle also is a simple Brayton cycle, and the bottoming cycle which is a Rankine cycle with reheating cycle is based on the steam parameters of conventional subcritical thermal power generation (540degC, 18 MPa). The optimization results showed that the cycle efficiency of the combined cycle plan 2 is the highest, the second is the helium turbine direct cycle, and the combined cycle plan 2 is the lowest. When the reactor outlet temperature is 900degC and the pressure ratio is 2.02, the cycle efficiency of the combined cycle plan 2 can reach 49.7%. The helium turbine direct cycle has a reactor inlet temperature above 500degC due to the regenerating cycle, so it requires a cooling circuit for the internal wall of the reactor pressure vessel. When the reactor outlet temperature increases, the increase of the pressure ratio required by the helium turbine direct cycle increases may bring some difficulties to the design and manufacture of the magnetic bearings. For the combined cycle, the reactor inlet temperature can be controlled below than 370degC, so the reactor pressure vessel can use SA533 steel without cooling the internal wall of the reactor pressure vessel. The pressure

  3. Increased resiliency and activity of microbial mediated carbon cycling enzymes in diversified bioenergy cropping systems

    Science.gov (United States)

    Upton, R.; Bach, E.; Hofmockel, K. S.

    2017-12-01

    Microbes are mediators of soil carbon (C) and are influenced in membership and activity by nitrogen (N) fertilization and inter-annual abiotic factors. Microbial communities and their extracellular enzyme activities (EEA) are important parameters that influence ecosystem C cycling properties and are often included in microbial explicit C cycling models. In an effort to generate model relevant, empirical findings, we investigated how both microbial community structure and C degrading enzyme activity are influenced by inter-annual variability and N inputs in bioenergy crops. Our study was performed at the Comparison of Biofuel Systems field-site from 2011 to 2014, in three bioenergy cropping systems, continuous corn (CC) and two restored prairies, both fertilized (FP) and unfertilized (P). We hypothesized microbial community structure would diverge during the prairie restoration, leading to changes in C cycling enzymes over time. Using a sequencing approach (16S and ITS) we determined the bacterial and fungal community structure response to the cropping system, fertilization, and inter-annual variability. Additionally, we used EEA of β-glucosidase, cellobiohydrolase, and β-xylosidase to determine inter-annual and ecosystem impacts on microbial activity. Our results show cropping system was a main effect for microbial community structure, with corn diverging from both prairies to be less diverse. Inter-annual changes showed that a drought occurring in 2012 significantly impacted microbial community structure in both the P and CC, decreasing microbial richness. However, FP increased in microbial richness, suggesting the application of N increased resiliency to drought. Similarly, the only year in which C cycling enzymes were impacted by ecosystem was 2012, with FP supporting higher potential enzymatic activity then CC and P. The highest EEA across all ecosystems occurred in 2014, suggesting the continued root biomass and litter build-up in this no till system

  4. (cc)-(anti canti c) (diquark-antidiquark) states in e/sup +/e/sup -/ annihilation

    Energy Technology Data Exchange (ETDEWEB)

    Chao, K T [Fermi National Accelerator Lab., Batavia, IL (USA)

    1981-01-01

    The mass spectrum and decay modes of the (cc)-(anti canti c) states are estimated in a quark-gluon model. We argue that the peculiar resonance-like structures of R(e/sup +/e/sup -/ ..-->.. hadrons) for ..sqrt..s = 6 to 7 GeV may be due to production of the P-wave (cc)-(anti canti c) states. They are predicted to lie in the range 6.4 to 6.8 GeV and mainly decay into charmed mesons.

  5. (cc)-(anti canti c) (diquark-antidiquark) states in e/sup +/e/sup -/ annihilation

    Energy Technology Data Exchange (ETDEWEB)

    Chao, K T

    1981-02-01

    The mass spectrum and decay modes of the (cc)-(anti canti c) states are estimated in a quark-gluon model. We argue that the peculiar resonance-like structures of R(e/sup +/e/sup -/ ..-->.. hadrons) for ..sqrt..s = 6-7 GeV may be due to production of the P-wave (cc)-(anti canti c) states. They are predicted to lie in the range 6.4-6.8 GeV and mainly decay into charmed mesons.

  6. Long life nickel electrodes for a nickel-hydrogen cell: Cycle life tests

    Science.gov (United States)

    Lim, H. S.; Verzwyvelt, S. A.

    1985-01-01

    In order to develop a long life nickel electrode for a Ni/H2 cell, the cycle life of nickel electrodes was tested in Ni/H2 boiler plate cells. A 19 test cell matrix was made of various nickel electrode designs including three levels each of plaque mechanical strength, median pore size of the plaque, and active material loading. Test cells were cycled to the end of their life (0.5v) in a 45 minute low Earth orbit cycle regime at 80% depth-of-discharge. It is shown that the active material loading level affects the cycle life the most with the optimum loading at 1.6 g/cc void. Mechanical strength does not affect the cycle life noticeably in the bend strength range of 400 to 700 psi. It is found that the best plaque is made of INCO nickel powder type 287 and has median pore size of 13 micron.

  7. Computational Fluid Dynamic Modeling of Rocket Based Combined Cycle Engine Flowfields

    Science.gov (United States)

    Daines, Russell L.; Merkle, Charles L.

    1994-01-01

    Computational Fluid Dynamic techniques are used to study the flowfield of a fixed geometry Rocket Based Combined Cycle engine operating in rocket ejector mode. Heat addition resulting from the combustion of injected fuel causes the subsonic engine flow to choke and go supersonic in the slightly divergent combustor-mixer section. Reacting flow computations are undertaken to predict the characteristics of solutions where the heat addition is determined by the flowfield. Here, adaptive gridding is used to improve resolution in the shear layers. Results show that the sonic speed is reached in the unheated portions of the flow first, while the heated portions become supersonic later. Comparison with results from another code show reasonable agreement. The coupled solutions show that the character of the combustion-based thermal choking phenomenon can be controlled reasonably well such that there is opportunity to optimize the length and expansion ratio of the combustor-mixer.

  8. [Characterization and transcriptional analysis of a new CC chemokine associated with innate imimune response in cobia (Rachycentron canadum)].

    Science.gov (United States)

    Su, Y; Feng, J; Sun, X; Guo, Z; Xu, L; Jiang, J

    2013-01-01

    Chemokines are small, secreted cytokine peptides, known principally for their ability to induce migration and activation of leukocyte populations under both pathological and physiological conditions. On the basis of previously constructed express sequence tags (ESTs) of the head kidney and spleen cDNA library of the perciform marine fish Rachycentron canadum (common name cobia). We used bi-directional rapid amplification of cDNA ends (RACE) and obtained a full-length cDNA of a new CC chemokine gene (designated RcCC3). The RcCC3 putative peptide exhibits sequence similarity to the group of CCL19/21/25 CC chemokines. The reverse transcription quantitative polymerase chain reaction (RT-qPCR) was used in transcript expression studies of RcCC3. We examined the constitutive expression of the transcripts in 12 tissues of non-stressed cobia; RcCC3 transcripts were detected in all tissues examined, with the highest expression in gill and liver, following by head kidney, kidney, spleen, skin, intestine, muscle, stomach, heart, blood and brain. Transcript expression of RcCC3 was examined in immune-related organs, including head kidney, spleen and liver, following intraperitoneal injection of phosphate-buffered saline control, polyriboinosinic polyribocytidylic acid (poly(I:C)) and formalin-killed Vibrio carchariae (bacterial vaccine). The transcripts in these tissues were quickly up-regulated by the injection of poly(I:C) and bacterial vaccine at early time points, although with different expression profiles. These results indicate RcCC3 represents an important component of innate immunity in cobia.

  9. Narrowing the Broader Autism Phenotype: A Study Using the Communication Checklist-Adult Version (CC-A)

    Science.gov (United States)

    Whitehouse, Andrew J. O.; Coon, Hilary; Miller, Judith; Salisbury, Bryanna; Bishop, Dorothy V. M.

    2010-01-01

    This study investigated whether the Communication Checklist-Adult (CC-A) could identify subtypes of social and communication dysfunction in autism probands and their parents. The CC-A is divided into subscales measuring linguistic ability as well as two aspects of social communication: the Pragmatic Skills subscale assesses the level of pragmatic…

  10. A review on the use of gas and steam turbine combined cycles as prime movers for large ships. Part I: Background and design

    International Nuclear Information System (INIS)

    Haglind, Fredrik

    2008-01-01

    The aim of the present paper is to review the prospects of using combined cycles as prime movers for large ships, like, container ships, tankers and bulk carriers. The paper is divided into three parts of which this paper constitutes Part I. Here, the environmental and human health concerns of international shipping are outlined. The regulatory framework relevant for shipping and the design of combined cycles are discussed. In Part II, previous work and experience are reviewed, and an overview of the implications of introducing combined cycles as prime movers is included. In Part III, marine fuels are discussed and the pollutant emissions of gas turbines are compared with those of two-stroke, slow-speed diesel engines. Environmental effects of shipping include contributions to the formation of ground-level ozone, acidification, eutrophication and climate impact. Tightening environmental regulations limit the fuel sulphur content and pollutant emissions. For moderate live steam pressures, a vertical HRSG of drum-type mounted directly over the gas turbine, is suggested to be a viable configuration that minimizes ground floor and space requirements

  11. Recovery of flue gas energy in heat-integrated gasification combined cycle (IGCC) power plants using the contact economizer system

    CSIR Research Space (South Africa)

    Madzivhandila, VA

    2011-03-01

    Full Text Available (flue gas) stream of a heat-integrated gasification combined cycle (IGCC) design of the Elcogas plant adopted from previous studies. The underlying support for this idea was the direct relationship between efficiency of the IGCC and the boiler feedwater...

  12. Metformin-clomiphene citrate vs. clomiphene citrate alone: Polycystic ovarian syndrome

    Directory of Open Access Journals (Sweden)

    Aqueela Ayaz

    2013-01-01

    Full Text Available Background: Polycystic ovary syndrome (PCOS is the commonest endocrinopathy in women that is associated with reproductive and metabolic disorders. Objectives: We compared the ovulation and conception rates after the treatment with clomiphene citrate (CC alone and in combination with metformin in infertile patients presented with polycystic ovarian syndrome (PCOS. Materials and Methods: This randomized controlled trial of independent cases and controls was conducted at the Department of Obstetrics and Gynecology, Hera General Hospital, Makkah, Saudi Arabia from February 01 to December 31, 2008. The 42 subjects diagnosed as PCOS were divided into group A and B (21 subjects in each for management with CC + metformin and CC alone, respectively. Group A received 500 mg three times a day of metformin continuously from the first cycle for 6 months or till pregnancy was confirmed. In both groups CC was started at a dose of 50 mg from day-2 till day-6 of the menstrual cycle. The dose of CC was increased to 100 mg in second and 150 mg in third cycle, and then remained 150 mg for the remaining three cycles. With ovulation the dose of CC was unaltered in both groups. Data were analyzed using Statistical Package for the Social Sciences (SPSS version 16. Results: More than 50% females in both groups were had body mass index > 25. Group A achieved high rate of regular cycles, ovulation success, and conception than group B (71.4% vs. 38.1%; P = 0.03, (76.2% vs. 38.1%; P = 0.021, and (66.6% vs. 28.6%; P = 0.01, respectively. Conclusion: Management with metformin + CC increased the ovulation and conception rates.

  13. Energy materials coordinating committee (EMaCC). Annual technical report, fiscal year 2005

    Energy Technology Data Exchange (ETDEWEB)

    None, None

    2006-09-29

    The DOE Energy Materials Coordinating Committee (EMaCC) serves primarily to enhance coordination among the Department's materials programs and to further effective use of materials expertise within the Department. These functions are accomplished through the exchange of budgetary and planning information among program managers and through technical meetings/workshops on selected topics involving both DOE and major contractors. In addition, EMaCC assists in obtaining materials-related inputs for both intra- and interagency compilations. Topical subcommittees of the EMaCC are responsible for conducting seminars and otherwise facilitating information flow between DOE organizational units in materials areas of particular importance to the Department. The EMaCC Terms of Reference were recently modified and developed into a Charter that was approved on June 5, 2003. As a result of this reorganization, the existing subcommittees were disbanded and new subcommittees are being formed. The FY 2004 budget summary for DOE Materials Activities is presented on page 8. The distribution of these funds between DOE laboratories, private industry, academia and other organizations is presented in tabular form on page 10. Following the budget summary is a set of detailed program descriptions for the FY 2004 DOE Materials activities. These descriptions are presented according to the organizational structure of the Department. A mission statement, a budget summary listing the project titles and FY 2004 funding, and detailed project summaries are presented for each Assistant Secretary office, the Office of Science, and the National Nuclear Security Administration. The project summaries also provide DOE, laboratory, academic and industrial contacts for each project, as appropriate.

  14. Energy materials coordinating committee (EMaCC). Annual technical report, fiscal year 2004

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2005-08-31

    The DOE Energy Materials Coordinating Committee (EMaCC) serves primarily to enhance coordination among the Department's materials programs and to further effective use of materials expertise within the Department. These functions are accomplished through the exchange of budgetary and planning information among program managers and through technical meetings/workshops on selected topics involving both DOE and major contractors. In addition, EMaCC assists in obtaining materials-related inputs for both intra- and interagency compilations. Topical subcommittees of the EMaCC are responsible for conducting seminars and otherwise facilitating information flow between DOE organizational units in materials areas of particular importance to the Department. The EMaCC Terms of Reference were recently modified and developed into a Charter that was approved on June 5, 2003. As a result of this reorganization, the existing subcommittees were disbanded and new subcommittees are being formed. The FY 2004 budget summary for DOE Materials Activities is presented on page 8. The distribution of these funds between DOE laboratories, private industry, academia and other organizations is presented in tabular form on page 10. Following the budget summary is a set of detailed program descriptions for the FY 2004 DOE Materials activities. These descriptions are presented according to the organizational structure of the Department. A mission statement, a budget summary listing the project titles and FY 2004 funding, and detailed project summaries are presented for each Assistant Secretary office, the Office of Science, and the National Nuclear Security Administration. The project summaries also provide DOE, laboratory, academic and industrial contacts for each project, as appropriate.

  15. The State of the Art Ten Years After a State of the Art

    DEFF Research Database (Denmark)

    Sturm, Bob L.

    2014-01-01

    A decade has passed since the first review of research on a ``flagship application" of music information retrieval (MIR): the problem of music genre recognition (MGR). During this time, about 500 works addressing MGR have been published, and at least 10 campaigns have been run to evaluate MGR sys......, the problems of validity in evaluation also affect research in music emotion recognition and autotagging. We conclude by discussing the implications of our work for MGR and MIR in the next ten years....

  16. Energy Materials Coordinating Committee (EMaCC). Annual Technical Report, Fiscal Year 2000

    Energy Technology Data Exchange (ETDEWEB)

    none,

    2001-07-31

    The Energy Materials Coordinating Committee Annual Report (attached, DOE/SC-0040) provides an annual summary of non-classified materials-related research programs supported by various elements within the Department of Energy. The EMaCC Annual Report is a useful working tool for project managers who want to know what is happening in other divisions, and it provides a guide for persons in industry and academia to the materials program within the Department. The major task of EMaCC this year was to make the Annual Report a more user-friendly document by removing redundant program information and shortening the project summaries.

  17. Similarity transformed coupled cluster response (ST-CCR) theory--a time-dependent similarity transformed equation-of-motion coupled cluster (STEOM-CC) approach.

    Science.gov (United States)

    Landau, Arie

    2013-07-07

    This paper presents a new method for calculating spectroscopic properties in the framework of response theory utilizing a sequence of similarity transformations (STs). The STs are preformed using the coupled cluster (CC) and Fock-space coupled cluster operators. The linear and quadratic response functions of the new similarity transformed CC response (ST-CCR) method are derived. The poles of the linear response yield excitation-energy (EE) expressions identical to the ones in the similarity transformed equation-of-motion coupled cluster (STEOM-CC) approach. ST-CCR and STEOM-CC complement each other, in analogy to the complementarity of CC response (CCR) and equation-of-motion coupled cluster (EOM-CC). ST-CCR/STEOM-CC and CCR/EOM-CC yield size-extensive and size-intensive EEs, respectively. Other electronic-properties, e.g., transition dipole strengths, are also size-extensive within ST-CCR, in contrast to STEOM-CC. Moreover, analysis suggests that in comparison with CCR, the ST-CCR expressions may be confined to a smaller subspace, however, the precise scope of the truncation can only be determined numerically. In addition, reformulation of the time-independent STEOM-CC using the same parameterization as in ST-CCR, as well as an efficient truncation scheme, is presented. The shown convergence of the time-dependent and time-independent expressions displays the completeness of the presented formalism.

  18. Recent Advances in Ring-Opening Functionalization of Cycloalkanols by C-C σ-Bond Cleavage.

    Science.gov (United States)

    Wu, Xinxin; Zhu, Chen

    2018-06-01

    Cycloalkanols prove to be privileged precursors for the synthesis of distally substituted alkyl ketones and polycyclic aromatic hydrocarbons (PAHs) by virtue of cleavage of their cyclic C-C bonds. Direct functionalization of cyclobutanols to build up other chemical bonds (e. g., C-F, C-Cl, C-Br, C-N, C-S, C-Se, C-C, etc.) has been achieved by using the ring-opening strategy. Mechanistically, the C-C cleavage of cyclobutanols can be involved in two pathways: (a) transition-metal catalyzed β-carbon elimination; (b) radical-mediated 'radical clock'-type ring opening. The recent advances of our group for the ring-opening functionalization of tertiary cycloalkanols are described in this account. © 2018 The Chemical Society of Japan & Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  19. Scalable data structure detection and classification for C/C++ binaries

    NARCIS (Netherlands)

    Haller, I.; Slowinska, J.M.; Bos, H.J.

    2015-01-01

    Many existing techniques for reversing data structures in C/C ++ binaries are limited to low-level programming constructs, such as individual variables or structs. Unfortunately, without detailed information about a program's pointer structures, forensics and reverse engineering are exceedingly

  20. Energy Materials Coordinating Committee (EMaCC) annual technical report, fiscal year 1984 with fiscal year 1985 data

    Energy Technology Data Exchange (ETDEWEB)

    None

    1985-07-01

    The Department of Energy funded about 374 million dollars of materials science and technology activities in both fiscal years 1984 and 1985. These funds and the commensurate program management responsibilities resided in 21 DOE program offices, each of which has its own mission and responsibilities. The Energy Materials Coordinating Committee (EMaCC) provides a formal mechanism to insure coordinated planning and maximum programmatic effectiveness for the Department's 374 million dollar per year materials effort. The EMaCC reports to the Director of the Office of Energy Research who in turn has oversight responsibilities for proper coordination of the technical programs of the Department. In carrying out this responsibility, EMaCC hosts meetings, organizes working groups, and publishes an annual technical report. This report is mandated by the EMaCC Terms of Reference. Its purpose is to disseminate information on the DOE materials programs for more effective coordination. It describes the materials research programs of various offices and divisions within the Department for FY 1984, contains funding information for FYs 1984 and 1985, and summarizes EMaCC activities for FY 1985.

  1. Energy Materials Coordinating Committee (EMaCC) annual technical report, fiscal year 1984 with fiscal year 1985 data

    International Nuclear Information System (INIS)

    1985-07-01

    The Department of Energy funded about 374 million dollars of materials science and technology activities in both fiscal years 1984 and 1985. These funds and the commensurate program management responsibilities resided in 21 DOE program offices, each of which has its own mission and responsibilities. The Energy Materials Coordinating Committee (EMaCC) provides a formal mechanism to insure coordinated planning and maximum programmatic effectiveness for the Department's 374 million dollar per year materials effort. The EMaCC reports to the Director of the Office of Energy Research who in turn has oversight responsibilities for proper coordination of the technical programs of the Department. In carrying out this responsibility, EMaCC hosts meetings, organizes working groups, and publishes an annual technical report. This report is mandated by the EMaCC Terms of Reference. Its purpose is to disseminate information on the DOE materials programs for more effective coordination. It describes the materials research programs of various offices and divisions within the Department for FY 1984, contains funding information for FYs 1984 and 1985, and summarizes EMaCC activities for FY 1985

  2. Histological heterogeneity in primary and metastatic classic combined hepatocellular-cholangiocarcinoma: a case series.

    Science.gov (United States)

    De Vito, Claudio; Sarker, Debashis; Ross, Paul; Heaton, Nigel; Quaglia, Alberto

    2017-11-01

    Combined hepatocellular-cholangiocarcinoma (cHCC-CC) is a rare and aggressive primary liver cancer with both hepatocellular and cholangiocellular differentiation. Due to its bi-phenotypic component, cHCC-CC is a heterogeneous tumour and histopathological analysis of metastatic deposits is poorly characterized. In this retrospective study, we describe four patients in whom the histology from resected specimens of both primary and recurrent and/or metastatic tumour was available for comparison and immunohistochemical characterization. Our study shows that recurrent or metastatic deposits replicate the heterogeneity of the primary cHCC-CC, that even originally small foci of divergent differentiation can become predominant later on and that hepatocellular and cholangiocellular components can show different tropism in distant organs. In our experience, the behaviour of recurrent/metastatic cHCC-CC is unpredictable and histological examination is necessary to guide treatment options at present.

  3. Life cycle analysis of distributed concentrating solar combined heat and power: economics, global warming potential and water

    Science.gov (United States)

    Norwood, Zack; Kammen, Daniel

    2012-12-01

    We report on life cycle assessment (LCA) of the economics, global warming potential and water (both for desalination and water use in operation) for a distributed concentrating solar combined heat and power (DCS-CHP) system. Detailed simulation of system performance across 1020 sites in the US combined with a sensible cost allocation scheme informs this LCA. We forecast a levelized cost of 0.25 kWh-1 electricity and 0.03 kWh-1 thermal, for a system with a life cycle global warming potential of ˜80 gCO2eq kWh-1 of electricity and ˜10 gCO2eq kWh-1 thermal, sited in Oakland, California. On the basis of the economics shown for air cooling, and the fact that any combined heat and power system reduces the need for cooling while at the same time boosting the overall solar efficiency of the system, DCS-CHP compares favorably to other electric power generation systems in terms of minimization of water use in the maintenance and operation of the plant. The outlook for water desalination coupled with distributed concentrating solar combined heat and power is less favorable. At a projected cost of 1.40 m-3, water desalination with DCS-CHP would be economical and practical only in areas where water is very scarce or moderately expensive, primarily available through the informal sector, and where contaminated or salt water is easily available as feed-water. It is also interesting to note that 0.40-1.90 m-3 is the range of water prices in the developed world, so DCS-CHP desalination systems could also be an economical solution there under some conditions.

  4. Numerical Simulation of Fluidized Bed Gasifier for Integrated Gasification Combined Cycle

    Directory of Open Access Journals (Sweden)

    CHEN Ju-hui

    2017-06-01

    Full Text Available The overall thermal efficiency of the integrated gasification combined cycle ( IGCC has not been sufficiently improved. In order to achieve higher power generation efficiency,the advanced technology of IGCC has been developed which is on the basis of the concept of exergy recovery. IGCC systems and devices from the overall structure of opinion,this technology will generate electricity for the integration of advanced technology together,the current utilization of power generation technology and by endothermic reaction of steam in the gasifier,a gas turbine exhaust heat recovery or the solid oxide fuel cell. It is estimated that such the use of exergy recycling has the advantage of being easy to use,separating,collecting fixed CO2,making it very attractive,and can increase the overall efficiency by 10% or more. The characteristics of fluidized bed gasifier,one of the core equipment of the IGCC system,and its effect on the whole system were studied.

  5. First report of a thioredoxin homologue in jellyfish: molecular cloning, expression and antioxidant activity of CcTrx1 from Cyanea capillata.

    Directory of Open Access Journals (Sweden)

    Zengliang Ruan

    Full Text Available Thioredoxins (Trx proteins are a family of small, highly-conserved and ubiquitous proteins that play significant roles in the resistance of oxidative damage. In this study, a homologue of Trx was identified from the cDNA library of tentacle of the jellyfish Cyanea capillata and named CcTrx1. The full-length cDNA of CcTrx1 was 479 bp with a 312 bp open reading frame encoding 104 amino acids. Bioinformatics analysis revealed that the putative CcTrx1 protein harbored the evolutionarily-conserved Trx active site 31CGPC34 and shared a high similarity with Trx1 proteins from other organisms analyzed, indicating that CcTrx1 is a new member of Trx1 sub-family. CcTrx1 mRNA was found to be constitutively expressed in tentacle, umbrella, oral arm and gonad, indicating a general role of CcTrx1 protein in various physiological processes. The recombinant CcTrx1 (rCcTrx1 protein was expressed in Escherichia coli BL21 (DE3, and then purified by affinity chromatography. The rCcTrx1 protein was demonstrated to possess the expected redox activity in enzymatic analysis and protection against oxidative damage of supercoiled DNA. These results indicate that CcTrx1 may function as an important antioxidant in C. capillata. To our knowledge, this is the first Trx protein characterized from jellyfish species.

  6. Evaluation of ejector performance for an organic Rankine cycle combined power and cooling system

    International Nuclear Information System (INIS)

    Zhang, Kun; Chen, Xue; Markides, Christos N.; Yang, Yong; Shen, Shengqiang

    2016-01-01

    Highlights: • The performance of an ejector in an Organic Rankine Cycle and ejector refrigeration cycle (EORC) was evaluated. • The achieved entrainment ratio and COP of an EORC system is affected significantly by the evaporator conditions (such as temperature, pressure and flow rate). • An optimum distance of 6 mm nozzle position was found that ensures a maximum entrainment ratio, the best efficiency and lowest loss in the ejector. • A reduced total pressure loss between the nozzle inlet and exit leads to a lower energy loss, a higher entrainment ratio and better overall ejector performance. - Abstract: Power-generation systems based on organic Rankine cycles (ORCs) are well suited and increasingly employed in the conversion of thermal energy from low temperature heat sources to power. These systems can be driven by waste heat, for example from various industrial processes, as well as solar or geothermal energy. A useful extension of such systems involves a combined ORC and ejector-refrigeration cycle (EORC) that is capable, at low cost and complexity, of producing useful power while having a simultaneous capacity for cooling that is highly desirable in many applications. A significant thermodynamic loss in such a combined energy system takes place in the ejector due to unavoidable losses caused by irreversible mixing in this component. This paper focuses on the flow and transport processes in an ejector, in order to understand and quantify the underlying reasons for these losses, as well as their sensitivity to important design parameters and operational variables. Specifically, the study considers, beyond variations to the geometric design of the ejector, also the role of changing the external conditions across this component and how these affect its performance; this is not only important in helping develop ejector designs in the first instance, but also in evaluating how the performance may shift (in fact, deteriorate) quantitatively when the device

  7. Synergistic combinations of high hydrostatic pressure and essential oils or their constituents and their use in preservation of fruit juices.

    Science.gov (United States)

    Espina, Laura; García-Gonzalo, Diego; Laglaoui, Amin; Mackey, Bernard M; Pagán, Rafael

    2013-01-15

    This work addresses the inactivation achieved with Escherichia coli O157:H7 and Listeria monocytogenes EGD-e by combined processes of high hydrostatic pressure (HHP) and essential oils (EOs) or their chemical constituents (CCs). HHP treatments (175-400 MPa for 20 min) were combined with 200 μL/L of each EO (Citrus sinensis L., Citrus lemon L., Citrus reticulata L., Thymus algeriensis L., Eucalyptus globulus L., Rosmarinus officinalis L., Mentha pulegium L., Juniperus phoenicea L., and Cyperus longus L.) or each CC ((+)-limonene, α-pinene, β-pinene, p-cymene, thymol, carvacrol, borneol, linalool, terpinen-4-ol, 1,8-cineole, α-terpinyl acetate, camphor, and (+)-pulegone) in buffer of pH 4.0 or 7.0. The tested combinations achieved different degrees of inactivation, the most effective being (+)-limonene, carvacrol, C. reticulata L. EO, T. algeriensis L. EO and C. sinensis L. EO which were capable of inactivating about 4-5 log(10) cycles of the initial cell populations in combination with HHP, and therefore showed outstanding synergistic effects. (+)-Limonene was also capable of inactivating 5 log(10) cycles of the initial E. coli O157:H7 population in combination with HHP (300 MPa for 20 min) in orange and apple juices, and a direct relationship was established between the inactivation degree caused by the combined process with (+)-limonene and the occurrence of sublethal injury after the HHP treatment. This work shows the potential of EOs and CCs in the inactivation of foodborne pathogens in combined treatments with HHP, and proposes their possible use in liquid food such as fruit juices. Copyright © 2012 Elsevier B.V. All rights reserved.

  8. Waste Handling Equipment Development Test and Evaluation Study

    International Nuclear Information System (INIS)

    R.L. Tome

    1998-01-01

    The purpose of this study is to identify candidate Monitored Geologic Repository (MGR) surface waste handling equipment for development testing. This study will also identify strategies for performing the development tests. Development testing shall be implemented to support detail design and reduce design risks. Development testing shall be conducted to confirm design concepts, evaluate alternative design concepts, show the availability of needed technology, and provide design documentation. The candidate equipment will be selected from MGR surface waste handling equipment that is the responsibility of the Management and Operating Contractor (M and O) Surface Design Department. The equipment identified in this study is based on Viability Assessment (VA) design. The ''Monitored Geologic Repository Test and Evaluation Plan'' (MGR T and EP), Reference 5.1, was used as a basis for this study. The MGR T and EP reflects the extent of test planning and analysis that can be conducted, given the current status of the MGR requirements and latest VA design information. The MGR T and EP supports the appropriate sections in the license application (LA) in accordance with 10 CFR 60.2 1(c)(14). The MGR T and EP describes the following test activities: site characterization to confirm, by test and analysis, the suitability of the Yucca Mountain site for housing a geologic repository; development testing to investigate and document design concepts to reduce risk; qualification testing to verify equipment compliance with design requirements, specifications, and regulatory requirements; system testing to validate compliance with MGR requirements, which include the receipt, handling, retrieval, and disposal of waste; periodic performance testing to verify preclosure requirements and to demonstrate safe and reliable MGR operation; and performance confirmation modeling, testing, and analysis to verify adherence to postclosure regulatory requirements. Development test activities can be

  9. Release and sorption of alkali metals in coal fired combined cycle power systems; Freisetzung und Einbindung von Alkalimetallverbindungen in kohlebefeuerten Kombikraftwerken

    Energy Technology Data Exchange (ETDEWEB)

    Mueller, Michael

    2009-07-01

    Coal fired combined cycle power systems will be a sufficient way to increase the efficiency of coal combustion. However, combined cycle power systems require a reliable hot gas cleanup. Especially alkali metals, such as sodium and potassium, can lead to hot corrosion of the gas turbine blading if they condensate as sulphates. The actual work deals with the release and sorption of alkali metals in coal fired combined cycle power systems. The influence of coal composition, temperature and pressure on the release of alkali species in coal combustion was investigated and the relevant release mechanisms identified. Alumosilicate sorbents have been found that reduce the alkali concentration in the hot flue gas of the Circulating Pressurized Fluidized Bed Combustion 2{sup nd} Generation (CPFBC 2{sup nd} Gen.) at 750 C to values sufficient for use in a gas turbine. Accordingly, alumosilicate sorbents working at 1400 C have been found for the Pressurized Pulverized Coal Combustion (PPCC). The sorption mechanisms have been identified. Thermodynamic calculations were performed to upscale the results of the laboratory experiments to conditions prevailing in power systems. According to these calculations, there is no risk of hot corrosion in both processes. Furthermore, thermodynamic calculations were performed to investigate the behaviour of alkali metals in an IGCC with integrated hot gas cleanup and H{sub 2} membrane for CO{sub 2} sequestration. (orig.)

  10. MEGA-CC: computing core of molecular evolutionary genetics analysis program for automated and iterative data analysis.

    Science.gov (United States)

    Kumar, Sudhir; Stecher, Glen; Peterson, Daniel; Tamura, Koichiro

    2012-10-15

    There is a growing need in the research community to apply the molecular evolutionary genetics analysis (MEGA) software tool for batch processing a large number of datasets and to integrate it into analysis workflows. Therefore, we now make available the computing core of the MEGA software as a stand-alone executable (MEGA-CC), along with an analysis prototyper (MEGA-Proto). MEGA-CC provides users with access to all the computational analyses available through MEGA's graphical user interface version. This includes methods for multiple sequence alignment, substitution model selection, evolutionary distance estimation, phylogeny inference, substitution rate and pattern estimation, tests of natural selection and ancestral sequence inference. Additionally, we have upgraded the source code for phylogenetic analysis using the maximum likelihood methods for parallel execution on multiple processors and cores. Here, we describe MEGA-CC and outline the steps for using MEGA-CC in tandem with MEGA-Proto for iterative and automated data analysis. http://www.megasoftware.net/.

  11. CC2D1A Regulates Human Intellectual and Social Function as well as NF-κB Signaling Homeostasis

    Directory of Open Access Journals (Sweden)

    M. Chiara Manzini

    2014-08-01

    Full Text Available Autism spectrum disorder (ASD and intellectual disability (ID are often comorbid, but the extent to which they share common genetic causes remains controversial. Here, we present two autosomal-recessive “founder” mutations in the CC2D1A gene causing fully penetrant cognitive phenotypes, including mild-to-severe ID, ASD, as well as seizures, suggesting shared developmental mechanisms. CC2D1A regulates multiple intracellular signaling pathways, and we found its strongest effect to be on the transcription factor nuclear factor κB (NF-κB. Cc2d1a gain and loss of function both increase activation of NF-κB, revealing a critical role of Cc2d1a in homeostatic control of intracellular signaling. Cc2d1a knockdown in neurons reduces dendritic complexity and increases NF-κB activity, and the effects of Cc2d1a depletion can be rescued by inhibiting NF-κB activity. Homeostatic regulation of neuronal signaling pathways provides a mechanism whereby common founder mutations could manifest diverse symptoms in different patients.

  12. Experimental study on thermophysical properties of C/C composites at high temperature

    Institute of Scientific and Technical Information of China (English)

    ZHANG Wei; YI Fa-jun; HAN Jie-cai; MENG Song-he

    2006-01-01

    The coefficient of thermal expansion, thermal diffusivity and specific heat of C/C composites from room temperature to ultra high temperature were experimentally investigated. Thermal conductivity and thermal stress resistance of the composites were therefore computed based on experimental results. The results show that the composite has a very low thermal expansion coefficient. Thermal diffusivity decreases exponentially with temperature increase. The specific heat increases linearly as the temperature rises, and the variation trend of thermal conductivity is similar to that of thermal diffusivity. The thermal stress coefficient of C/C composite has little change with temperature variation, and thermal stress resistance of the composite at high temperature is stable.

  13. High-efficiency low LCOE combined cycles for sour gas oxy-combustion with CO[subscript 2] capture

    OpenAIRE

    Chakroun, Nadim Walid; Ghoniem, Ahmed F

    2015-01-01

    The growing concerns over global warming and carbon dioxide emissions have driven extensive research into novel ways of capturing carbon dioxide in power generation plants. In this regard, oxy-fuel combustion has been considered as a promising technology. One unconventional fuel that is considered is sour gas, which is a mixture of methane, hydrogen sulfide and carbon dioxide. In this paper, carbon dioxide is used as the dilution medium in the combustor and different combined cycle configurat...

  14. Clomiphene citrate, metformin or a combination of both as the first line ovulation induction drug for Asian Indian women with polycystic ovarian syndrome: A randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Sujata Kar

    2015-01-01

    Full Text Available Aim: To compare clomiphene citrate (CC, metformin or the combination of CC and metformin as the first line ovulation induction drug in Asian Indian women with polycystic ovary syndrome (PCOS. Methods: One hundred and five newly diagnosed, treatment naive PCOS women were recruited. They were randomized into any of the three groups: Group I (CC 50-150 mg/day, Group II (metformin 1700 mg/day, and Group III (CC + metformin in similar dosage to Groups I and II. Patients underwent follicular monitoring and advice on timed intercourse. The study period was 6 months, or till pregnant, or till CC resistant. Primary outcome studied was live birth rate (LBR. Secondary outcomes were ovulation rate, pregnancy rate, and early pregnancy loss rate. Results: There was no significant difference among the groups in baseline characteristics and biochemical parameters. LBR was 41.6%, 37.5%, and 28.1%, respectively in Groups III, II, and I. Group III (CC + metformin had the highest ovulation (83.3%, pregnancy (50%, and LBRs (41.6%. Group II (metformin was as good as Group I (CC in all the outcomes. CC + metformin (Group III had statistically significantly higher ovulation rate as compared to CC alone (Group I (P = 0.03; odds ratio: 95% confidence interval: 3.888 [1.08-13.997]. Conclusion: Thus, our study shows that metformin was as good as CC in terms of "LBR" and the combination of CC and metformin gave the highest ovulation and LBR.

  15. Survival effect of PDGF-CC rescues neurons from apoptosis in both brain and retina by regulating GSK3β phosphorylation

    Science.gov (United States)

    Tang, Zhongshu; Arjunan, Pachiappan; Lee, Chunsik; Li, Yang; Kumar, Anil; Hou, Xu; Wang, Bin; Wardega, Piotr; Zhang, Fan; Dong, Lijin; Zhang, Yongqing; Zhang, Shi-Zhuang; Ding, Hao; Fariss, Robert N.; Becker, Kevin G.; Lennartsson, Johan; Nagai, Nobuo; Cao, Yihai

    2010-01-01

    Platelet-derived growth factor CC (PDGF-CC) is the third member of the PDGF family discovered after more than two decades of studies on the original members of the family, PDGF-AA and PDGF-BB. The biological function of PDGF-CC remains largely to be explored. We report a novel finding that PDGF-CC is a potent neuroprotective factor that acts by modulating glycogen synthase kinase 3β (GSK3β) activity. In several different animal models of neuronal injury, such as axotomy-induced neuronal death, neurotoxin-induced neuronal injury, 6-hydroxydopamine–induced Parkinson’s dopaminergic neuronal death, and ischemia-induced stroke, PDGF-CC protein or gene delivery protected different types of neurons from apoptosis in both the retina and brain. On the other hand, loss-of-function assays using PDGF-C null mice, neutralizing antibody, or short hairpin RNA showed that PDGF-CC deficiency/inhibition exacerbated neuronal death in different neuronal tissues in vivo. Mechanistically, we revealed that the neuroprotective effect of PDGF-CC was achieved by regulating GSK3β phosphorylation and expression. Our data demonstrate that PDGF-CC is critically required for neuronal survival and may potentially be used to treat neurodegenerative diseases. Inhibition of the PDGF-CC–PDGF receptor pathway for different clinical purposes should be conducted with caution to preserve normal neuronal functions. PMID:20231377

  16. Aero-Thermo-Structural Analysis of Inlet for Rocket Based Combined Cycle Engines

    Science.gov (United States)

    Shivakumar, K. N.; Challa, Preeti; Sree, Dave; Reddy, Dhanireddy R. (Technical Monitor)

    2000-01-01

    NASA has been developing advanced space transportation concepts and technologies to make access to space less costly. One such concept is the reusable vehicles with short turn-around times. The NASA Glenn Research Center's concept vehicle is the Trailblazer powered by a rocket-based combined cycle (RBCC) engine. Inlet is one of the most important components of the RBCC engine. This paper presents fluid flow, thermal, and structural analysis of the inlet for Mach 6 free stream velocity for fully supersonic and supercritical with backpressure conditions. The results concluded that the fully supersonic condition was the most severe case and the largest stresses occur in the ceramic matrix composite layer of the inlet cowl. The maximum tensile and the compressive stresses were at least 3.8 and 3.4, respectively, times less than the associated material strength.

  17. Effect of magnetic reconnection in stellar plasma

    Science.gov (United States)

    Hammoud, M.; El Eid, M.; Darwish, M.

    2017-06-01

    An important phenomenon in Astrophysics is the process of magnetic reconnection (MGR), which is envisaged to understand the solar flares, coronal mass ejection, interaction of the solar wind with the Earth’s magnetic field (so called geomagnetic storm) and other phenomena. In addition, it plays a role in the formation of stars. MGR involves topological change of a set of magnetic field lines leading to a new equilibrium configuration of lower magnetic energy. The MGR is basically described in the framework of the Maxwell’s equations linked to Navier-Stockes equations. Nevertheless, many details are still not understood. In this paper, we investigate the MGR process in the framework of the Magnetohydrodynamic (MHD) model of a single conducting fluid using a modern powerful computational tool (OpenFOAM). We will show that the MGR process takes place only if resistivity exists. However, despite the high conductivity of the plasma, resistivity becomes effective in a very thin layer generating sharp gradients of the magnetic field, and thus accelerating the reconnection process. The net effect of MGR is that magnetic energy is converted into thermal and kinetic energies leading to heating and acceleration of charged particles. The Sun’s coronal ejection is an example of the MGR process.

  18. Corrosion behavior of Haynes registered 230 registered nickel-based super-alloys for integrated coal gasification combined cycle syngas plants. A plant exposure study

    International Nuclear Information System (INIS)

    Lee, Sungkyu; Lee, Jieun; Kang, Suk-Hwan; Lee, Seung-Jong; Yun, Yongseung; Kim, Min Jung

    2015-01-01

    The corrosion behavior of commercially available Haynes registered 230 registered nickel-based alloy samples was investigated by exposure to coal-gasifying integrated coal gasification combined cycle pilot plant facilities affiliated with the Institute for Advanced Engineering (2.005 MPa and 160-300 C). The morphological and microstructural analyses of the exposed samples were conducted using scanning electron microscopy and energy-dispersive X-ray spectroscopy analysis on the external surface of the recovered corrosion test samples to obtain information of the corrosion scale. These analyses based on the pre- and post-exposure corrosion test samples combined with thermodynamic Ellingham-Pourbaix stability diagrams provided preliminary insight into the mechanism of the observed corrosion behavior prevailing in the piping materials that connected the particulate removal unit and water scrubber of the integrated coal gasification combined cycle pilot plant. Uniform material wastage was observed after 46 hours of operation, and a preliminary corrosion mechanism was suggested: the observed material waste and corrosion behavior of the Haynes registered 230 registered nickel-based alloy samples cut off from the coal syngas integrated coal gasification combined cycle plant were explained by the formation of discontinuous (complex) oxide phases and subsequent chlorine-induced active oxidation under the predominantly reducing environment encountered. This contribution continues the already published studies of the Fe-Ni-Cr-Co alloy Haynes registered 556 registered .

  19. Identification of a PVL-negative SCCmec-IVa sub-lineage of the methicillin-resistant Staphylococcus aureus CC80 lineage

    DEFF Research Database (Denmark)

    Edslev, Sofie Marie; Westh, Henrik Torkil; Andersen, Paal Skytt

    2018-01-01

    of the CC80 S. aureus lineage was conducted from whole-genome sequences of 217 isolates (23 MSSA and 194 MRSA) from 22 countries. All isolates were further genetically characterized in regard to resistance determinants and PVL carriage, and epidemiological data was obtained for selected isolates. RESULTS....... CONCLUSIONS: This study reports the emergence of a novel CC80 CA-MRSA sub-lineage, showing that the CC80 lineage is more diverse than previously assumed....

  20. Combination of one-view digital breast tomosynthesis with one-view digital mammography versus standard two-view digital mammography: per lesion analysis

    Energy Technology Data Exchange (ETDEWEB)

    Gennaro, Gisella; Bezzon, Elisabetta; Pescarini, Luigi; Polico, Ilaria; Proietti, Alessandro; Baldan, Enrica; Pomerri, Fabio; Muzzio, Pier Carlo [Veneto Institute of Oncology (IRCCS), Padua (Italy); Hendrick, R.E. [University of Colorado-Denver, Department of Radiology, School of Medicine, Aurora, CO (United States); Toledano, Alicia [Biostatistics Consulting, LLC, Kensington, MD (United States); Paquelet, Jean R. [Advanced Medical Imaging Consultants, Fort Collins, CO (United States); Breast Imaging, McKee Medical Center, Loveland, CO (United States); Chersevani, Roberta [Private Medical Practice, Gorizia (Italy); Di Maggio, Cosimo [Private Medical Practice, Padua (Italy); La Grassa, Manuela [Department of Radiology, Oncological Reference Center (IRCCS), Aviano (Italy)

    2013-08-15

    To evaluate the clinical value of combining one-view mammography (cranio-caudal, CC) with the complementary view tomosynthesis (mediolateral-oblique, MLO) in comparison to standard two-view mammography (MX) in terms of both lesion detection and characterization. A free-response receiver operating characteristic (FROC) experiment was conducted independently by six breast radiologists, obtaining data from 463 breasts of 250 patients. Differences in mean lesion detection fraction (LDF) and mean lesion characterization fraction (LCF) were analysed by analysis of variance (ANOVA) to compare clinical performance of the combination of techniques to standard two-view digital mammography. The 463 cases (breasts) reviewed included 258 with one to three lesions each, and 205 with no lesions. The 258 cases with lesions included 77 cancers in 68 breasts and 271 benign lesions to give a total of 348 proven lesions. The combination, DBT{sub (MLO)}+MX{sub (CC)}, was superior to MX (CC+MLO) in both lesion detection (LDF) and lesion characterization (LCF) overall and for benign lesions. DBT{sub (MLO)}+MX{sub (CC)} was non-inferior to two-view MX for malignant lesions. This study shows that readers' capabilities in detecting and characterizing breast lesions are improved by combining single-view digital breast tomosynthesis and single-view mammography compared to two-view digital mammography. (orig.)

  1. Comparison of the effects of ovarian cauterization and gonadotropin-releasing hormone agonist and oral contraceptive therapy combination on endocrine changes in women with polycystic ovary disease.

    Science.gov (United States)

    Taskin, O; Yalcinoglu, A I; Kafkasli, A; Burak, F; Ozekici, U

    1996-06-01

    To study the effects of laparoscopic ovarian cauterization and combination of long-acting GnRH agonist (GnRH-a) and oral contraceptive (OC) therapy on endocrine changes in women with clomiphene citrate (CC)- resistant polycystic ovary disease (PCOD). Prospective, randomized. University-based infertility clinic. Seventeen women with CC-resistant PCOD were included randomly in the study to either laparoscopic ovarian cautery or GnRH-a and OC therapy for 3 months. Serum concentrations of LH, FSH, androstenedione (A), T, and sex hormone-binding globulin (SHBG) were determined before each therapeutic approach and during the follicular phase of first menstrual cycle after the cessation of each treatment. The mean serum concentrations and the clinical profiles were similar in both groups. Both groups showed significant changes in LH, FSH, A, T, and SHBG compared with pretreatment levels. There were no significant differences in the final concentrations of LH, FSH, and A between the two study groups after each treatment, whereas T and SHBG levels were significantly different in the goserelin and OC group. The decrease in LH and increase in SHBG serum concentrations were greater in the goserelin and OC-treated women [-59% and + 5.9% versus - 70% and + 13.5%, respectively]. Although the SHBG concentration increased in both groups, the serum SHBG concentration of the goserelin and OC group was significantly higher than the other group. Both therapeutic modalities revealed similar effects on the endocrine profiles in women with CC-resistant PCOD. Considering the invasiveness, cost, and potential complications of laparoscopic ovarian cauterization, noninvasive medical treatment with GnRH-a and OC combination may be more effective in restoring the optimal follicular environment in women with PCOD.

  2. Transcriptomes of Frankia sp. strain CcI3 in growth transitions

    Directory of Open Access Journals (Sweden)

    Bickhart Derek M

    2011-08-01

    Full Text Available Abstract Background Frankia sp. strains are actinobacteria that form N2-fixing root nodules on angiosperms. Several reference genome sequences are available enabling transcriptome studies in Frankia sp. Genomes from Frankia sp. strains differ markedly in size, a consequence proposed to be associated with a high number of indigenous transposases, more than 200 of which are found in Frankia sp. strain CcI3 used in this study. Because Frankia exhibits a high degree of cell heterogeneity as a consequence of its mycelial growth pattern, its transcriptome is likely to be quite sensitive to culture age. This study focuses on the behavior of the Frankia sp. strain CcI3 transcriptome as a function of nitrogen source and culture age. Results To study global transcription in Frankia sp. CcI3 grown under different conditions, complete transcriptomes were determined using high throughput RNA deep sequencing. Samples varied by time (five days vs. three days and by culture conditions (NH4+ added vs. N2 fixing. Assembly of millions of reads revealed more diversity of gene expression between five-day and three-day old cultures than between three day old cultures differing in nitrogen sources. Heat map analysis organized genes into groups that were expressed or repressed under the various conditions compared to median expression values. Twenty-one SNPs common to all three transcriptome samples were detected indicating culture heterogeneity in this slow-growing organism. Significantly higher expression of transposase ORFs was found in the five-day and N2-fixing cultures, suggesting that N starvation and culture aging provide conditions for on-going genome modification. Transposases have previously been proposed to participate in the creating the large number of gene duplication or deletion in host strains. Subsequent RT-qPCR experiments confirmed predicted elevated transposase expression levels indicated by the mRNA-seq data. Conclusions The overall pattern of

  3. Energy and Rate Determinations to Activate the C-C σ-BOND of Acetone by Gaseous NI^+

    Science.gov (United States)

    Castleberry, Vanessa A.; Dee, S. Jason; Villarroel, Otsmar J.; Laboren, Ivanna E.; Frey, Sarah E.; Bellert, Darrin J.

    2009-06-01

    A unique application of a custom fabricated photodissociation spectrometer permits the determination of thermodynamic properties (activation energies), reaction rates, and mechanistic details of bare metal cation mediated C-C σ-bond activation in the gas phase. Specifically, the products and rates resulting from the unimolecular decomposition of the Ni^+Acetone (Ni^+Ac) adduct are monitored after absorption of a known amount of energy. The three dissociative products which are observed in high yield are Ni^+, Ni^+CO, and CH3CO^+. The latter two fragment ions result from the activation of a C-C σ-bond. It was found that minimally 14 000 cm^{-1} of energy must be deposited into the adduct ion to induce C-C bond breakage. Preliminary results for the Ni^+ activation of the C-C σ-bond of acetone indicate that there are (at least) two low energy reaction coordinates leading to C-C bond breakage. The lower energy pathway emerges from the doublet ground state with an upper limit to the activation energy of 14 000 cm^{-1} and reaction rate ≈0.14 molecules/μs. The higher energy path is assumed to be along the quartet reaction coordinate with a minimum activation energy of 18 800 cm^{-1} (relative to the ground state) and a slightly slower reaction rate.

  4. Performance analysis of a combined organic Rankine cycle and vapor compression cycle for power and refrigeration cogeneration

    International Nuclear Information System (INIS)

    Kim, Kyoung Hoon; Perez-Blanco, Horacio

    2015-01-01

    A thermodynamic analysis of cogeneration of power and refrigeration activated by low-grade sensible energy is presented in this work. An organic Rankine cycle (ORC) for power production and a vapor compression cycle (VCC) for refrigeration using the same working fluid are linked in the analysis, including the limiting case of cold production without net electricity production. We investigate the effects of key parameters on system performance such as net power production, refrigeration, and thermal and exergy efficiencies. Characteristic indexes proportional to the cost of heat exchangers or of turbines, such as total number of transfer units (NTU tot ), size parameter (SP) and isentropic volumetric flow ratio (VFR) are also examined. Three important system parameters are selected, namely turbine inlet temperature, turbine inlet pressure, and the flow division ratio. The analysis is conducted for several different working fluids. For a few special cases, isobutane is used for a sensitivity analysis due to its relatively high efficiencies. Our results show that the system has the potential to effectively use low grade thermal sources. System performance depends both on the adopted parameters and working fluid. - Highlights: • Waste heat utilization can reduce emissions of carbon dioxide. • The ORC/VCC cycle can deliver power and/or refrigeration using waste heat. • Efficiencies and size parameters are used for cycle evaluation. • The cycle performance is studied for eight suitable refrigerants. Isobutane is used for a sensitivity analysis. • The work shows that the isobutene cycle is quite promising.

  5. Life cycle analysis of distributed concentrating solar combined heat and power: economics, global warming potential and water

    International Nuclear Information System (INIS)

    Norwood, Zack; Kammen, Daniel

    2012-01-01

    We report on life cycle assessment (LCA) of the economics, global warming potential and water (both for desalination and water use in operation) for a distributed concentrating solar combined heat and power (DCS-CHP) system. Detailed simulation of system performance across 1020 sites in the US combined with a sensible cost allocation scheme informs this LCA. We forecast a levelized cost of $0.25 kWh −1 electricity and $0.03 kWh −1 thermal, for a system with a life cycle global warming potential of ∼80 gCO 2 eq kWh −1 of electricity and ∼10 gCO 2 eq kWh −1 thermal, sited in Oakland, California. On the basis of the economics shown for air cooling, and the fact that any combined heat and power system reduces the need for cooling while at the same time boosting the overall solar efficiency of the system, DCS-CHP compares favorably to other electric power generation systems in terms of minimization of water use in the maintenance and operation of the plant. The outlook for water desalination coupled with distributed concentrating solar combined heat and power is less favorable. At a projected cost of $1.40 m −3 , water desalination with DCS-CHP would be economical and practical only in areas where water is very scarce or moderately expensive, primarily available through the informal sector, and where contaminated or salt water is easily available as feed-water. It is also interesting to note that $0.40–$1.90 m −3 is the range of water prices in the developed world, so DCS-CHP desalination systems could also be an economical solution there under some conditions. (letter)

  6. Immune response CC Chemokines, CCL2 and CCL5 are associated with Pulmonary Sarcoidosis

    LENUS (Irish Health Repository)

    Palchevskiy, Vyacheslav

    2011-04-04

    Abstract Background Pulmonary sarcoidosis involves an intense leukocyte infiltration of the lung with the formation of non-necrotizing granulomas. CC chemokines (chemokine (C-C motif) ligand 2 (CCL2)-CCL5) are chemoattractants of mononuclear cells and act through seven transmembrane G-coupled receptors. Previous studies have demonstrated conflicting results with regard to the associations of these chemokines with sarcoidosis. In an effort to clarify previous discrepancies, we performed the largest observational study to date of CC chemokines in bronchoalveolar lavage fluid (BALF) from patients with pulmonary sarcoidosis. Results BALF chemokine levels from 72 patients affected by pulmonary sarcoidosis were analyzed by enzyme-linked immunosorbent assay (ELISA) and compared to 8 healthy volunteers. BALF CCL3 and CCL4 levels from pulmonary sarcoidosis patients were not increased compared to controls. However, CCL2 and CCL5 levels were elevated, and subgroup analysis showed higher levels of both chemokines in all stages of pulmonary sarcoidosis. CCL2, CCL5, CC chemokine receptor type 1 (CCR1), CCR2 and CCR3 were expressed from mononuclear cells forming the lung granulomas, while CCR5 was only found on mast cells. Conclusions These data suggest that CCL2 and CCL5 are important mediators in recruiting CCR1, CCR2, and CCR3 expressing mononuclear cells as well as CCR5-expressing mast cells during all stages of pulmonary sarcoidosis.

  7. Immune response CC chemokines CCL2 and CCL5 are associated with pulmonary sarcoidosis.

    Science.gov (United States)

    Palchevskiy, Vyacheslav; Hashemi, Nastran; Weigt, Stephen S; Xue, Ying Ying; Derhovanessian, Ariss; Keane, Michael P; Strieter, Robert M; Fishbein, Michael C; Deng, Jane C; Lynch, Joseph P; Elashoff, Robert; Belperio, John A

    2011-04-04

    Pulmonary sarcoidosis involves an intense leukocyte infiltration of the lung with the formation of non-necrotizing granulomas. CC chemokines (chemokine (C-C motif) ligand 2 (CCL2)-CCL5) are chemoattractants of mononuclear cells and act through seven transmembrane G-coupled receptors. Previous studies have demonstrated conflicting results with regard to the associations of these chemokines with sarcoidosis. In an effort to clarify previous discrepancies, we performed the largest observational study to date of CC chemokines in bronchoalveolar lavage fluid (BALF) from patients with pulmonary sarcoidosis. BALF chemokine levels from 72 patients affected by pulmonary sarcoidosis were analyzed by enzyme-linked immunosorbent assay (ELISA) and compared to 8 healthy volunteers. BALF CCL3 and CCL4 levels from pulmonary sarcoidosis patients were not increased compared to controls. However, CCL2 and CCL5 levels were elevated, and subgroup analysis showed higher levels of both chemokines in all stages of pulmonary sarcoidosis. CCL2, CCL5, CC chemokine receptor type 1 (CCR1), CCR2 and CCR3 were expressed from mononuclear cells forming the lung granulomas, while CCR5 was only found on mast cells. These data suggest that CCL2 and CCL5 are important mediators in recruiting CCR1, CCR2, and CCR3 expressing mononuclear cells as well as CCR5-expressing mast cells during all stages of pulmonary sarcoidosis.

  8. Optimisation of environmental gas cleaning routes for solid wastes cogeneration systems. Part II - Analysis of waste incineration combined gas/steam cycle

    International Nuclear Information System (INIS)

    Holanda, Marcelo R.; Perrella Balestieri, Jose A.

    2008-01-01

    In the first paper of this paper (Part I), conditions were presented for the gas cleaning technological route for environomic optimisation of a cogeneration system based in a thermal cycle with municipal solid waste incineration. In this second part, an environomic analysis is presented of a cogeneration system comprising a combined cycle composed of a gas cycle burning natural gas with a heat recovery steam generator with no supplementary burning and a steam cycle burning municipal solid wastes (MSW) to which will be added a pure back pressure steam turbine (another one) of pure condensation. This analysis aims to select, concerning some scenarios, the best atmospheric pollutant emission control routes (rc) according to the investment cost minimisation, operation and social damage criteria. In this study, a comparison is also performed with the results obtained in the Case Study presented in Part I

  9. Thermoeconomic evaluation and optimization of a Brayton–Rankine–Kalina combined triple power cycle

    International Nuclear Information System (INIS)

    Singh, Omendra Kumar; Kaushik, S.C.

    2013-01-01

    Highlights: • Combustion chamber performance can improve much by investment in efficient design. • Steam turbine performance would also improve by investment in efficient design. • Minimum total cost rate of plant found at gas cycle pressure ratio of around 14. • Total cost rate decreases significantly by decreasing the inlet air temperature. • Total cost rate decreases a little by increasing the inlet air relative humidity. - Abstract: This paper presents thermoeconomic analysis and optimization of a Brayton–Rankine–Kalina combined triple power cycle using Specific Exergy Costing (SPECO) methodology. Cost-balance and auxiliary equations are formulated for each component and for each node and solved through a MATLAB program to get the average cost per unit exergy at different state points. To evaluate the cost effectiveness of the system, the values of thermoeconomic variables for each component are calculated. Large relative cost difference is observed in the steam turbine, HRSG’s, combustion chambers, compressors, recuperators and ammonia–water evaporator. Therefore, these components require greater attention. The performance of steam turbine, combustion chambers, recuperators and ammonia–water evaporator can be appreciably improved by capital investment into more efficient design due to their low values of exergoeconomic factor. The performance of HRSG’s can be improved only marginally due to slightly higher value of exergoeconomic factor but no such recommendation can be made for the compressors which have a quite high value of exergoeconomic factor. The objective function of the thermoeconomic optimization is the minimization of the total cost rate for the whole plant. Its minimum value is found to occur at a gas cycle pressure ratio of around 14. Decreasing inlet air temperature decreases this objective function parameter significantly while increasing relative humidity causes a small decrease in it

  10. Predominant Dissemination of PVL-Negative CC89 MRSA with SCCmec Type II in Children with Impetigo in Japan

    Directory of Open Access Journals (Sweden)

    H. Kikuta

    2011-01-01

    Full Text Available Background. The ratio of CA-MRSA in children with impetigo has been increasing in Japan. Methods. Antimicrobial susceptibilities of 136 S. aureus isolates from children with impetigo were studied. Furthermore, molecular epidemiological analysis and virulence gene analysis were performed. Results. Of the 136 S. aureus isolates, 122 (89.7% were MSSA and 14 (10.3% were MRSA. Of the 14 MRSA strains, 11 belonged to CC89 (ST89, ST91, and ST2117 and carried diverse types of SCCmec: type II (IIb: 3 strains; unknown subtype: 4 strains, type IVa (2 strains, and unknown type (2 strains. The remaining three strains exhibited CC8 (ST-8-SCCmec type VIa, CC121 (ST121-SCCmec type V, and CC5 (ST5-nontypeable SCCmec element, respectively. None were lukS-PV-lukF-PV gene positive. Gentamicin- and clarithromycin-resistant strains were frequently found in both MRSA and MSSA. Conclusions. PVL-negative CC89-SCCmec type II strains are the most predominant strains among the CA-MRSA strains circulating in the community in Japan.

  11. Association of serum Clara cell protein CC16 with respiratory infections and immune response to respiratory pathogens in elite athletes.

    Science.gov (United States)

    Kurowski, Marcin; Jurczyk, Janusz; Jarzębska, Marzanna; Moskwa, Sylwia; Makowska, Joanna S; Krysztofiak, Hubert; Kowalski, Marek L

    2014-04-15

    Respiratory epithelium integrity impairment caused by intensive exercise may lead to exercise-induced bronchoconstriction. Clara cell protein (CC16) has anti-inflammatory properties and its serum level reflects changes in epithelium integrity and airway inflammation. This study aimed to investigate serum CC16 in elite athletes and to seek associations of CC16 with asthma or allergy, respiratory tract infections (RTIs) and immune response to respiratory pathogens. The study was performed in 203 Olympic athletes. Control groups comprised 53 healthy subjects and 49 mild allergic asthmatics. Serum levels of CC16 and IgG against respiratory viruses and Mycoplasma pneumoniae were assessed. Allergy questionnaire for athletes was used to determine symptoms and exercise pattern. Current versions of ARIA and GINA guidelines were used when diagnosing allergic rhinitis and asthma, respectively. Asthma was diagnosed in 13.3% athletes, of whom 55.6% had concomitant allergic rhinitis. Allergic rhinitis without asthma was diagnosed in 14.8% of athletes. Mean CC16 concentration was significantly lower in athletes versus healthy controls and mild asthmatics. Athletes reporting frequent RTIs had significantly lower serum CC16 and the risk of frequent RTIs was more than 2-fold higher in athletes with low serum CC16 (defined as equal to or less than 4.99 ng/ml). Athletes had significantly higher anti-adenovirus IgG than healthy controls while only non-atopic athletes had anti-parainfluenza virus IgG significantly lower than controls. In all athletes weak correlation of serum CC16 and anti-parainfluenza virus IgG was present (R = 0.20, p athletes a weak positive correlations of CC16 with IgG specific for respiratory syncytial virus (R = 0.29, p = 0.009), parainfluenza virus (R = 0.31, p = 0.01) and adenovirus (R = 0.27, p = 0.02) were seen as well. Regular high-load exercise is associated with decrease in serum CC16 levels. Athletes with decreased CC16 are

  12. Phosphodiesterase activity is regulated by CC2D1A that is implicated in non-syndromic intellectual disability

    KAUST Repository

    Altawashi, Azza

    2013-07-04

    Background: Cyclic adenosine 3?5?-monophosphate (cAMP) is a key regulator of many cellular processes, including in the neuronal system, and its activity is tuned by Phosphodiesterase (PDE) activation. Further, the CC2D1A protein, consisting of N-Terminal containing four DM14 domains and C-terminal containing C2 domain, was shown to regulate the cAMP-PKA pathway. A human deletion mutation lacking the fourth DM14 and the adjacent C2 domain results in Non Syndromic Intellectual Disability (NSID) also referred to as Non Syndromic Mental Retardation (NSMR). Findings. Here we demonstrate that in Mouse Embryonic Fibroblasts (MEF) CC2D1A co-localizes with PDE4D in the cytosol before cAMP stimulation and on the periphery after stimulation, and that the movement to the periphery requires the full-length CC2D1A. In CC2D1A mouse mutant cells, the absence of three of the four DM14 domains abolishes migration of the complex to the periphery and causes constitutive phosphorylation of PDE4D Serine 126 (Sssup126esup) via the cAMP-dependent protein kinase A (PKA) resulting in PDE4D hyperactivity. Suppressing PDE4D activity with Rolipram in turn restores the down-stream phosphorylation of the "cAMP response element-binding protein" (CREB) that is defective in mouse mutant cells. Conclusion: Our findings suggest that CC2D1A is a novel regulator of PDE4D. CC2D1A interacts directly with PDE4D regulating its activity and thereby fine-tuning cAMP-dependent downstream signaling. Based on our in vitro evidence we propose a model which links CC2D1A structure and function to cAMP homeostasis thereby affecting CREB phosphorylation. We speculate that CC2D1A and/or PDE4D may be promising targets for therapeutic interventions in many disorders with impaired PDE4D function such as NSID. 2013 Al-Tawashi and Gehring; licensee BioMed Central Ltd.

  13. Life cycle of the potato golden cyst nematode (Globodera rostochiensis grown under climatic conditions in Belgrade

    Directory of Open Access Journals (Sweden)

    Bačić Jasmina

    2011-01-01

    Full Text Available The life cycle of a population of the quarantine nematode Globodera rostochiensis on the root of susceptible potato variety, Desiree, originating from an infected field (CC Ljubovija no. 413 on the mountain of Jagodnja in the district of Mačva, was studied under experimental conditions in Belgrade in 2002-2003. The golden cyst nematode completed one generation per year in the temperate climate of this region. In 2002, the life cycle lasted 29 days after the penetration of the second stage juveniles into the roots. An adverse effect of high soil temperatures above 25 °C was observed in 2003, influencing the development of the nematode and making the life cycle last two months longer.

  14. Turbulent Mixing of Primary and Secondary Flow Streams in a Rocket-Based Combined Cycle Engine

    Science.gov (United States)

    Cramer, J. M.; Greene, M. U.; Pal, S.; Santoro, R. J.; Turner, Jim (Technical Monitor)

    2002-01-01

    This viewgraph presentation gives an overview of the turbulent mixing of primary and secondary flow streams in a rocket-based combined cycle (RBCC) engine. A significant RBCC ejector mode database has been generated, detailing single and twin thruster configurations and global and local measurements. On-going analysis and correlation efforts include Marshall Space Flight Center computational fluid dynamics modeling and turbulent shear layer analysis. Potential follow-on activities include detailed measurements of air flow static pressure and velocity profiles, investigations into other thruster spacing configurations, performing a fundamental shear layer mixing study, and demonstrating single-shot Raman measurements.

  15. A life cycle assessment framework combining nutritional and environmental health impacts of diet: a case study on milk

    DEFF Research Database (Denmark)

    Stylianou, Katerina S.; Heller, Martin C.; Fulgoni III, Victor L.

    2016-01-01

    of less healthy foods (sugar-sweetened beverages). Further studies are needed to test whether this conclusion holds within a more comprehensive assessment of environmental and nutritional health impacts. Conclusions This case study provides the first quantitative epidemiology-based estimate......Purpose While there has been considerable effort to understand the environmental impact of a food or diet, nutritional effects are not usually included in food-related life cycle assessment (LCA). Methods We developed a novel Combined Nutritional and Environmental Life Cycle Assessment (CONE......-LCA) framework that evaluates and compares in parallel the environmental and nutritional effects of foods or diets. We applied this framework to assess human health impacts, expressed in Disability Adjusted Life Years (DALYs), in a proof-of conceptcase study that investigated the environmental and nutritional...

  16. Novel integrated gasification combined cycles with a carbon dioxide recovery option

    Energy Technology Data Exchange (ETDEWEB)

    Lawton, J.

    1997-08-01

    Two novel combined cycle configurations offering potential to reduce the cost of electricity from coal-fired IGCCs were investigated - one based on the use of flue gas recycling with heat recovery to the recycled stream, the other, aimed at removing carbon dioxide, using flue gas recycle and heat recovery but with oxygen as the oxidant in the gas turbine. The investigation included the use of fuels other than coal. It was found that gasification efficiency was increased by use of a coal/Orimulsion slurry. Flue gas recycling at 1 bar for the industrial gas turbine offered a gain of about 0.4 percentage points. In a standard IGCC the industrial gas turbine showed an advantage of 1.5 percentage points over the aero-derived machine. The least cost electricity with CO{sub 2} removal was achieved using an oxygen-fed industrial gas turbine with flue gas recycling and recovery. Several recommendations are made for further studies to reduce costs of electricity production. 11 refs., 3 figs., 5 tabs., 1 app.

  17. Hydrogen or Fossil Combustion Nuclear Combined Cycle Systems for Baseload and Peak Load Electricity Production. Annex X

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2013-12-15

    A combined cycle power plant is described that uses: (i) heat from a high temperature nuclear reactor to meet baseload electrical demands; and (ii) heat from the same high temperature reactor and burning natural gas, jet fuel or hydrogen to meet peak load electrical demands. For baseload electricity production, fresh air is compressed, then flows through a heat exchanger, where it is heated to between 700 and 900{sup o}C by using heat provided by a high temperature nuclear reactor via an intermediate heat transport loop, and finally exits through a high temperature gas turbine to produce electricity. The hot exhaust from the Brayton cycle gas turbine is then fed to a heat recovery steam generator that provides steam to a steam turbine for added electrical power production. To meet peak electricity demand, the air is first compressed and then heated with the heat from a high temperature reactor. Natural gas, jet fuel or hydrogen is then injected into the hot air in a combustion chamber, combusts and heats the air to 1300{sup o}C - the operating conditions for a standard natural gas fired combined cycle plant. The hot gas then flows through a gas turbine and a heat recovery steam generator before being sent to the exhaust stack. The higher temperatures increase the plant efficiency and power output. If hydrogen is used, it can be produced at night using energy from the nuclear reactor and stored until required. With hydrogen serving as the auxiliary fuel for peak power production, the electricity output to the electrical grid can vary from zero (i.e. when hydrogen is being produced) to the maximum peak power while the nuclear reactor operates at constant load. As nuclear heat raises air temperatures above the auto-ignition temperatures of the various fuels and powers the air compressor, the power output can be varied rapidly (compared with the capabilities of fossil fired turbines) to meet spinning reserve requirements and stabilize the electrical grid. This combined

  18. C=C bond cleavage on neutral VO3(V2O5)n clusters.

    Science.gov (United States)

    Dong, Feng; Heinbuch, Scott; Xie, Yan; Bernstein, Elliot R; Rocca, Jorge J; Wang, Zhe-Chen; Ding, Xun-Lei; He, Sheng-Gui

    2009-01-28

    The reactions of neutral vanadium oxide clusters with alkenes (ethylene, propylene, 1-butene, and 1,3-butadiene) are investigated by experiments and density function theory (DFT) calculations. Single photon ionization through extreme ultraviolet radiation (EUV, 46.9 nm, 26.5 eV) is used to detect neutral cluster distributions and reaction products. In the experiments, we observe products (V(2)O(5))(n)VO(2)CH(2), (V(2)O(5))(n)VO(2)C(2)H(4), (V(2)O(5))(n)VO(2)C(3)H(4), and (V(2)O(5))(n)VO(2)C(3)H(6), for neural V(m)O(n) clusters in reactions with C(2)H(4), C(3)H(6), C(4)H(6), and C(4)H(8), respectively. The observation of these products indicates that the C=C bonds of alkenes can be broken on neutral oxygen rich vanadium oxide clusters with the general structure VO(3)(V(2)O(5))(n=0,1,2...). DFT calculations demonstrate that the reaction VO(3) + C(3)H(6) --> VO(2)C(2)H(4) + H(2)CO is thermodynamically favorable and overall barrierless at room temperature. They also provide a mechanistic explanation for the general reaction in which the C=C double bond of alkenes is broken on VO(3)(V(2)O(5))(n=0,1,2...) clusters. A catalytic cycle for alkene oxidation on vanadium oxide is suggested based on our experimental and theoretical investigations. The reactions of V(m)O(n) with C(6)H(6) and C(2)F(4) are also investigated by experiments. The products VO(2)(V(2)O(5))(n)C(6)H(4) are observed for dehydration reactions between V(m)O(n) clusters and C(6)H(6). No product is detected for V(m)O(n) clusters reacting with C(2)F(4). The mechanisms of the reactions between VO(3) and C(2)F(4)/C(6)H(6) are also investigated by calculations at the B3LYP/TZVP level.

  19. Throughput and Delay Analysis of HARQ with Code Combining over Double Rayleigh Fading Channels

    KAUST Repository

    Chelli, Ali

    2018-01-15

    This paper proposes the use of hybrid automatic repeat request (HARQ) with code combining (HARQ-CC) to offer reliable communications over double Rayleigh channels. The double Rayleigh fading channel is of particular interest to vehicle-to-vehicle communication systems as well as amplify-and-forward relaying and keyhole channels. This work studies the performance of HARQ-CC over double Rayleigh channels from an information theoretic perspective. Analytical approximations are derived for the $\\\\epsilon$-outage capacity, the average number of transmissions, and the throughput of HARQ-CC. Moreover, we evaluate the delay experienced by Poisson arriving packets for HARQ-CC. We provide analytical expressions for the average waiting time, the packets sojourn time, the average consumed power, and the energy efficiency. In our investigation, we take into account the impact of imperfect feedback on different performance metrics. Additionally, we explore the tradeoff between energy efficiency and the throughput. The proposed scheme is shown to maintain the outage probability below a specified threshold $\\\\epsilon$ which ensures the link reliability. Meanwhile, HARQ-CC adapts implicitly the transmission rate to the channel conditions such that the throughput is maximized. Our results demonstrate that HARQ-CC allows improving the achievable communication rate compared to fixed time diversity schemes. To maximize the throughput of HARQ-CC, the rate per HARQ round should be less than the rate required to meet the outage constraint. Our investigation of the performance of HARQ-CC over Rayleigh and double Rayleigh channels shows that double Rayleigh channels have a higher severity of fading and result in a larger degradation of the throughput. Our analysis reveals that HARQ with incremental redundancy (HARQ-IR) achieves a larger throughput compared to HARQ-CC, while HARQ-CC is simpler to implement, has a lower decoding

  20. Graded Cycling Test Combined With the Talk Test Is Responsive in Cardiac Rehabilitation

    DEFF Research Database (Denmark)

    Nielsen, Susanne Grøn; Vinther, Anders

    2016-01-01

    PURPOSE: To evaluate clinical assessment outcome of cardiac rehabilitation, a simple and reliable submaximal exercise test, not based on heart rate, is warranted. The Talk Test (TT) has been found to correlate well with the ventilatory threshold, and excellent reliability was observed for TT...... combined with the Graded Cycling Test (GCT-TT) in cardiac patients. The purpose was to investigate responsiveness of GCT-TT in cardiac rehabilitation patients. METHODS: Patients (n = 93) referred to 8 weeks of cardiac rehabilitation were included. Pre- and posttests were performed using GCT-TT. Mean test...... changes in watts (W) were compared with the standard error of measurement (SEM95) for groups and the smallest real difference (SRD) for individuals. Minimal clinically important difference was assessed by comparing patient perceived changes in physical fitness with the test changes. RESULTS...