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Sample records for cavo adquirido na

  1. Tratamento cirúrgico de estrabismo restritivo adquirido na infância: relato de caso Surgical treatment of acquired restrictive strabismus in infancy: case report

    Directory of Open Access Journals (Sweden)

    Juliano Vescovi Damasceno

    2009-02-01

    Full Text Available Os autores relatam um caso raro e grave de estrabismo restritivo, adquirido nos primeiros meses de vida, em criança previamente normal, com intenso acometimento da musculatura extraocular e tecidos adjacentes. Discutem a possibilidade de doença inflamatória ou infecciosa como causa etiológica. A dificuldade da abordagem cirúrgica do caso, descrita nos três procedimentos anteriores, foi resolvida na última cirurgia, pela cooperação de cirurgiões de estrabismo e órbita, utilizando-se incisão ampla para cirurgia orbitária.The authors describe a severe and rare case of restrictive strabismus, acquired during the first semester of life, in a previously normal baby. They discuss the possibility of inflammatory or infectious disease as the primary cause. Surgical management was challenging, after three procedures and required the cooperation of strabismus and orbit specialists and also a wide incision for orbital surgery.

  2. Carbonaceous Asteroid Volatile Recovery (CAVoR) system, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — The Carbonaceous Asteroid Volatile Recovery (CAVoR) system produces water and hydrogen-rich syngas for propellant production, life support consumables, and...

  3. Anastomose cavo-pulmonar total sem uso de material protético

    Directory of Open Access Journals (Sweden)

    Valdester C. PINTO Jr.

    1998-07-01

    Full Text Available Objetivo: Demonstrar a viabilidade na feitura de túnel cava inferior-cava superior com retalho da parede atrial direita, evitando o emprego de material protético. Casuística e Métodos: Foram operados 2 pacientes nos quais se empregou a técnica de anastomose cavo-pulmonar total, sem uso de material protético. O primeiro caso, A.L.M., masc, 4 anos, 15 kg, era portador de atresia tricúspide (EP, com comunicação interventricular (CIV restritiva. O segundo caso, M.E.N.O., fem, 15 anos, 47 kg, tinha doença de Ebstein. O controle pós-operatório dos pacientes foi feito com ecocardiograma e cateterismo cardíaco. As operações foram realizadas com o emprego de circulação extracorpórea (CEC, e cardioplegia sangüínea como método de proteção miocárdica. A canulação das cavas foi o mais distal possível. A tunelização foi realizada com retalho de tecido atrial direito, suturado ao septo interatrial, deixando-se o seio coronariano e a comunicação interatrial (CIA para a esquerda. Resultados: Ambos os pacientes evoluíram, sem complicações, na UTI. O primeiro apresentou derrame pleural discreto à direita, e o segundo mantém-se em estimulação artificial (VVI,R. Conclusões: A tunelização intra-atrial para anastomose cavo-pulmonar total pode ser realizada sem o uso de material protético, evitando-se os riscos advindos do seu emprego (calcificação, retração, embolização.The authors describe two cases (one tricuspid atresia without TGA or pulmonary stenosis, but with a restrictive IVC: the second of an Ebstein disease of total cavo-pulmonary anastomosis using only the tissue of the atrial wall, avoiding any prosthetic material. Both cases were done under cardiopulmonary bypass and cold blood cardioplegia. A flap of the right atrial wall was used to re-direct the blood flow. Pleural effusion in one patient and complete AV block in the other were the complications found. They conclude that right intra-atrial tunneling for

  4. Staphylococcus aureus meticilino resistente adquirido na comunidade: um problema mundial

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    Síntia de Souza Evangelista

    2015-02-01

    Full Text Available Objetivo: descrever a epidemiologia dos casos de CA-MRSA no Brasil de forma a compreender sua ocorrência, fatores de risco associados e formas de manejo em relação à situação mundial. Método: revisão integrativa e para seleção dos estudos utilizou-se as bases de dados: Scopus, Science direct, Isi Web of Knowledge, PUBMED e BVS. Resultados: foram identificados dez artigos nacionais que descreveram 21 casos de CA-MRSA principalmente em crianças, adolescentes e adultos com quadro de infecção de pele e tecidos moles evoluindo para infecções graves relacionados ao clone Oceania Southwest Pacific Clone (OSPC que resultaram em hospitalização. Conclusão: apesar do CA-MRSA ser considerado um micro-organismo de relevância mundial verificou-se a escassez de dados publicados sobre sua epidemiologia no Brasil, o que dificultam o delineamento da realidade do país frente ao CA-MRSA.

  5. Direito adquirido e emendas constitucionais sob a ótica do direito intertemporal

    OpenAIRE

    Jaques, Gustavo

    2008-01-01

    O presente estudo, dissertação de Mestrado, dedica-se a questões relevantes no mundo jurídico. Aborda, especialmente, a preocupação com o respeito ao direito adquirido dos indivíduos em face das sucessivas alterações constitucionais em nosso ordenamento, assunto conjugado à análise do direito intertemporal. Nesse contexto, elabora-se larga explanação, doutrinária e jurisprudencial, acerca dos conflitos de leis no tempo, com ênfase na análise da irretroatividade e da aplicação imediata das lei...

  6. Ricerca clinico-epidemiologica sullo stato di salute del cavo orale nei pazienti tossicodipendenti

    OpenAIRE

    Bromo, Francesco

    2010-01-01

    Obiettivo: Lo scopo della ricerca è stato quello di mettere in evidenza la presenza di patologie del cavo orale in soggetti tossicodipendenti Materiali e Metodi: Sono stati reclutati 71 pazienti in terapia di recupero presso la Comunità Incontro di Amelia. I soggetti sono stati sottoposti a visite clinico-anamnestiche adottando una cartella clinica da noi stessi costruita. Risultati: Dei 71 soggetti tossicodipendenti, 42 facevano uso di eroina e 39 assumevano droghe per v...

  7. Acquired cavo-varus deformity caused by an accessory calcaneus: a case report and literature review

    International Nuclear Information System (INIS)

    Singh Baghla, Davinder Paul; Shariff, Sajid; Bashir, Waseem A.

    2010-01-01

    We describe an unusual cause of an acquired cavo-varus foot deformity produced by progressive enlargement of an accessory calcaneal ossicle. A 13-year-old boy with constitutional plano-valgus flat feet noted a gradual change in foot shape associated with lateral ankle pain on ambulation following an inversion injury 2 years earlier. CT and MRI scans confirmed a large accessory calcaneal ossicle lying within the sinus tarsi, with associated marrow oedema. Following surgical excision of the ossicle, the foot returned to its original shape and the symptoms were alleviated. This is the fifth reported case of an accessory calcaneal ossicle, but the only case that has occurred in a flatfooted individual. We also present the first reported MRI images of the lesion confirming pathological marrow oedema as a response to mechanical stress. (orig.)

  8. Indagini su conoscenze e comportamenti dei medici in tema di prevenzione delle neoplasie del cavo orale: primi risultati

    OpenAIRE

    G. Nicotera; A. Di Stasio; F. Angelillo

    2003-01-01

    Obiettivi: l’indagine si propone di valutare il livello di conoscenze ed i comportamenti dei medici italiani in merito alla prevenzione delle neoplasie del cavo orale.

    Metodi: lo studio è stato effettuato mediante l’invio postale ad un campione casuale di 500 di medici di medicina generale della regione Calabria di un questionario con 38 domande strutturate in 3 sezioni: caratteristiche anagrafiche e lavorati...

  9. Indagini su conoscenze e comportamenti dei medici in tema di prevenzione delle neoplasie del cavo orale: primi risultati

    Directory of Open Access Journals (Sweden)

    G. Nicotera

    2003-05-01

    Full Text Available

    Obiettivi: l’indagine si propone di valutare il livello di conoscenze ed i comportamenti dei medici italiani in merito alla prevenzione delle neoplasie del cavo orale.

    Metodi: lo studio è stato effettuato mediante l’invio postale ad un campione casuale di 500 di medici di medicina generale della regione Calabria di un questionario con 38 domande strutturate in 3 sezioni: caratteristiche anagrafiche e lavorative (sesso, età, anni di attività, etc., conoscenze (principali fattori di rischio, lesioni precancerose, sede di insorgenza, etc. e comportamenti (esame obiettivo del cavo orale, anamnesi personale, etc..

    Risultati: i dati si riferiscono ai primi 151 questionari
    restituiti. La maggior parte dei rispondenti è di
    sesso maschile, l’età media è di 51.4 anni, la media
    degli anni di attività lavorativa è 19 anni e meno dei
    due terzi dei medici afferma di lavorare più di 30
    ore settimanali. Relativamente al livello delle conoscenze,
    solo il 19% dei medici conosce almeno 3 dei principali fattori di rischio del cancro della cavità orale, poco più di un terzo (35.1% riconosce la leucoplachia e l’eritroplachia come le due principali lesioni precancerose associate alle neoplasie e il 56.7% identifica il carcinoma squamocellulare
    come la forma neoplastica più diffusa della bocca.

    Per quanto riguarda i comportamenti, i primi risultati si evidenziano che il 67% del campione effettua l’esame obiettivo del cavo orale e poco meno dei due raccoglie informazioni inerenti all’ uso/abuso di alcool e tabacco dei pazienti.

    Conclusioni: i primi risultati dello studio, se pur preliminari, fanno emergere l’importanza di pianificare interventi formativi in merito alla prevenzione delle neoplasie del cavo orale.

  10. Atividade simpática, parassimpática e metabólica influenciadas pelo comportamento da distribuição do suporte de peso em pé adquirido na condição de hemiparesia crônica

    OpenAIRE

    Ramos, Gabrielly Craveiro

    2016-01-01

    Introdução: O acidente vascular cerebral (AVC) é a causa mais frequente de incapacidade neurológica crônica da população adulta. Esta afecção cerebrovascular pode gerar alterações tanto no controle postural, observada por assimetria na distribuição do suporte de peso em pé, quanto no controle autonômico, verificadas por meio das respostas simpática e parassimpática na variabilidade da frequência cardíaca (VFC). Assim, a modificação combinada dos controles promovida pelo dano encefálico poderi...

  11. Metal-insulator transition induced in CaVO3 thin films

    International Nuclear Information System (INIS)

    Gu Man; Laverock, Jude; Chen, Bo; Smith, Kevin E.; Wolf, Stuart A.; Lu Jiwei

    2013-01-01

    Stoichiometric CaVO 3 (CVO) thin films of various thicknesses were grown on single crystal SrTiO 3 (STO) (001) substrates using a pulsed electron-beam deposition technique. The CVO films were capped with a 2.5 nm STO layer. We observed a temperature driven metal-insulator transition (MIT) in CVO films with thicknesses below 4 nm that was not observed in either thick CVO films or STO films. The emergence of this MIT can be attributed to the reduction in effective bandwidth due to a crossover from a three-dimensional metal to a two-dimensional insulator. The insulating phase was only induced with a drive current below 0.1 μA. X-ray absorption measurements indicated different electronic structures for thick and very thin films of CVO. Compared with the thick film (∼60 nm), thin films of CVO (2–4 nm) were more two-dimensional with the V charge state closer to V 4+ .

  12. Análise da presença do canal cavo-inter-radicular em molares: estudo in vitro = ‘In vitro’ analysis of acessory foramina in molar teeth

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    Cunha, Fernanda Silveira da

    2005-01-01

    Full Text Available Evidências significativas sugerem a inter-relação existente entre a região de furca de dentes multirradiculados com o desenvolvimento de lesões endo-periodontais, principalmente, quando da presença do canal cavo-inter-radicular. Com o objetivo de compreender os mecanismos envolvidos na etiopatogenia de tais doenças periodontais, assim como propiciar o diagnóstico e o tratamento precoces, buscou-se melhor caracterizar essa região dando ênfase à morfologia do assoalho da câmara pulpar. Para este estudo foram selecionados 42 molares humanos extraídos, sendo 21 superiores e 21 inferiores. Após realizadas as aberturas coronárias e localizadas as entradas dos canais radiculares, os dentes tiveram parte das porções coronária e radicular cortada perpendicularmente ao longo do seu eixo, com o auxílio de disco de carburundum. Depois de uma criteriosa limpeza dos espécimes, esses foram secos em câmara de ponto crítico, sendo, a seguir, preparados para análise em microscópio eletrônico de varredura (Philips®, modelo XL30, Holanda. Os dados foram analisados através do Teste U de Mann- Whitney e do teste Qui-quadrado. Com base nos resultados obtidos e de acordo com a literatura pertinente, pôde-se verificar que: 1. o diâmetro e o número de túbulos dentinários encontrados por mm2 assim como a presença de foraminas no assoalho da câmara pulpar sugerem a permeabilidade dessa região; 2. o diâmetro maior de algumas foraminas identifica a presença do canal cavo-inter-radicular

  13. Procesos de plasticidad cerebral en pacientes con daño adquirido

    OpenAIRE

    Márquez Noriego, Blanca Esther

    2016-01-01

    Los accidentes cerebrovasculares y los traumatismos craneoencefálicos son las dos patologías principales causantes de daño cerebral adquirido. Los avances médicos han permitido disminuir considerablemente la mortalidad derivada de dichas patologías. Consecuentemente, el número de personas que padecen déficits derivados de estas lesiones aumenta a nivel mundial. Estos déficits son consecuencia del daño cerebral, el cual puede afectar a varias áreas, según las características propias de la lesi...

  14. El conocimiento profesional adquirido por el entrenador de balonmano: experiencias y formación

    Directory of Open Access Journals (Sweden)

    Sebasti\\u00E1n Feu Molina

    2012-01-01

    Full Text Available El objetivo del estudio fue conocer la procedencia del conocimiento que utilizan los entrenadores de balonmano en su ejercicio profesional. En el estudio participaron 333 entrenadores españoles, 86.8% hombres y 13.2% mujeres. Se diseñó y validó un cuestionario que permitió conocer la influencia del conocimiento profesional en su intervención como entrenador: experiencia como jugador, formación académica o experiencia como entrenador. El análisis estadístico reflejó que los factores de la escala tenían una validez y fiabilidad adecuadas (¿ > .70, acreditando a este cuestionario como una herramienta válida y fiable. Los entrenadores utilizan las tres fuentes de conocimiento (académica, experiencia como jugador y autoformación, existiendo una mayor utilización del conocimiento académico. Los entrenadores con mayor formación utilizan menos las experiencias y conocimientos adquiridos como jugador y utilizan más los conocimientos adquiridos en su vida profesional.

  15. Medición del conocimiento adquirido en tecnología de la madera por industriales forestales en Costa Rica

    OpenAIRE

    Camacho-Cornejo, Luis Diego; Salas-Garita, Cynthia; Vargas-Fonseca, Lupita; Valverde-Otárola, Juan Carlos

    2017-01-01

    La cuantificación del conocimiento adquirido en individuos de edad adulta, permite no solo definir la efectividad de un sistema de aprendizaje, sino que también abre la posibilidad de definir las fortalezas y debilidades del sistema y analizar mejoras para el aumento de la retención de conocimiento; por lo cual el objetivo de este estudio consistió en cuantificar el conocimiento adquirido en tres temáticas de tecnología de la madera dirigidas a industriales forestales de Costa Rica. Se trabaj...

  16. Staphylococcus aureus resistente a meticilina adquirido en la comunidad aislados en tres hospitales de Lima-Perú

    Directory of Open Access Journals (Sweden)

    Jesús Tamariz

    2010-01-01

    Full Text Available Staphylococcus aureus es un importante patógeno involucrado en una serie de infecciones e intoxicaciones, presenta múltiples factores de virulencia y su impacto se incrementa por su notable resistencia a los antimicrobianos. Objetivo: Determinar la frecuencia de Staphylococcus aureus meticilino resistente adquiridos en la comunidad, en hospitales de Lima- Perú. Material y métodos: Se realizó un estudio descriptivo multicéntrico. La resistencia a meticilina se determinó por el método Oxacillin Agar Screen. El origen de la cepa fue determinado mediante los criterios de los CDC; la Leucocidina de Panton Valentine fue identificada por métodos moleculares. Resultados: Se aislaron 276 cepas de Staphylococcus aureus, 160 fueron resistentes a meticilina (58%, 9 de ellas fueron identificadas como adquiridas en la comunidad (5,6%. La PVL fue identificada en 25 cepas (9,1%, 14 fueron MSSA y 11 MRSA, de éstas últimas solo 4 fueron MRSAcom, 7 fueron MRSAhosp (p<0,001. Conclusiones: El estudio revela niveles elevados de resistencia a meticilina, pero niveles bajos de MRSAcom. En nuestro medio la presencia de PVL no constituiría un marcador para la identificación de los MRSAcom. (Rev Med Hered 2010;21:4-10.

  17. Métodos para la evaluación motora objetiva de pacientes con daño cerebral adquirido en neurorrehabilitación funcional

    OpenAIRE

    Villán Villán, Mailin Adriana

    2018-01-01

    El Daño Cerebral Adquirido (DCA) es una alteración de la actividad neuronal en áreas del cerebro que ocurre después del nacimiento. Las secuelas tras un episodio de DCA pueden ser motoras, cognitivas, sociales, entre otras, que pueden transformar la vida de los pacientes en los ámbitos educativo, laboral y familiar. Las causas del DCA pueden ser traumáticas y no traumáticas, siendo las más comunes el Accidente Cerebrovascular (ACV) o Ictus y el Traumatismo Craneoencefálico (TCE). El ACV es la...

  18. Primer aislamiento en Argentina de Staphylococcus aureus resistente a la meticilina adquirido en la comunidad con sensibilidad intermedia a la vancomicina y no sensibilidad a la daptomicina

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    Laura Errecalde

    Full Text Available Describimos el primer caso en Argentina de Staphylococcus aureus resistente a la meticilina adquirido en la comunidad con sensibilidad intermedia a la vancomicina y no sensibilidad a la daptomicina. Caso clínico: Paciente masculino, con antecedente de insuficiencia renal crónica en hemodiálisis y osteosíntesis de cadera debido a una fractura. Se internó por síndrome febril persistente luego del desplazamiento de la prótesis por un traumatismo. Se aisló de hemocultivos S. aureus resistente a la meticilina adquirido en la comunidad. Durante el tratamiento con vancomicina y daptomicina, se observó un aumento gradual de la CIM de vancomicina de 1 µg/ml (VSSA a 2 µg/ml (h-VISA y a 4 µg/ml (VISA, y la emergencia de no sensibilidad a daptomicina (CIM = 4 µg/ml. Al suspender la vancomicina y la daptomicina, la cepa revirtió al fenotipo de sensibilidad a ambas drogas. Es mandatorio evaluar por CIM la sensibilidad a vancomicina y a daptomicina intratratamiento cuando estas drogas se usan como terapia.

  19. Avaliação terapêutica e posológica da levotiroxina sódica em cães com hipotiroidismo primário adquirido

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    Viviani De Marco

    2012-10-01

    Full Text Available O hipotireoidismo primário adquirido é uma endocrinopatia frequentemente diagnosticada na espécie canina. A terapia consiste na suplementação oral com levotiroxina sódica (L-tiroxina, no entanto vários protocolos terapêuticos têm sido propostos pela literatura, com doses variando 11 a 44µg/kg uma a duas vezes ao dia, visto à grande variabilidade de absorção e meia-vida plasmática do fármaco. Foram estudados 30 cães com hipotiroidismo primário adquirido (13 machos e 17 fêmeas, idade média de 7,9±1,9 anos e peso médio de 19,1±12,6 kg atendidos no Hospital Veterinário da Universidade Guarulhos (UnG e no Serviço de Endocrinologia de duas clínicas particulares da cidade de São Paulo (2009-2011, com o objetivo de avaliar a posologia e a frequência de administração da L-tiroxina, mais frequentemente utilizada, capaz de garantir um controle terapêutico satisfatório, avaliado através dos sinais clínicos e do teste pós-tiroxina, além de correlacionar a dose de tiroxina empregada com o peso dos animais. A dose média de tiroxina utilizada em nossa casuística foi de 16,9±3,1µg/kg, sendo a frequência de administração a cada 12 horas em 50% dos casos. Para se investigar uma possível correlação entre o peso e a dosagem de tiroxina utilizada, uma vez que cães de pequeno porte apresentam maior taxa metabólica que cães de grande porte, os animais foram agrupados em grupo A, cães com peso 10 kg (n=18/30, 26,8±10,7 kg. A dose média de tiroxina empregada nos grupos A e B não apresentaram diferença estatística e foram, respectivamente, 16±3µg/kg e 17±3µg/kg. A frequência de administração foi 50% a cada 24 horas e 50% a cada 12 horas para ambos os grupos. Dessa forma, a dose de tiroxina não parece se correlacionar com o peso do animal, sendo imprevisível quem deverá receber dose e frequência máxima da medicação. O protocolo deve ser individualizado e o paciente devidamente monitorado.

  20. Angioedema adquirido autoimune de difícil controle em paciente com lúpus eritematoso sistêmico Intractable acquired autoimmune angioedema in a patient with systemic lupus erythematosus

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    Vilson Furlanetto Junior

    2010-02-01

    Full Text Available O angioedema adquirido é causado por diferentes medicamentos e doenças linfoproliferativas, e tem sido raramente relacionado com a presença de doenças autoimunes. Descrevemos aqui uma paciente de 47 anos com lúpus eritematoso sistêmico (LES com envolvimento cutâneo importante que desenvolveu angioedema recorrente localizado em face incluindo lábios e pálpebras, membros superiores e tórax, não acompanhado de urticária e com dosagem do inibidor de C1 esterase reduzida. A utilização de antimaláricos, glicocorticoides e pulsoterapia com metilprednisolona associada ao uso de azatioprina não determinou melhora. A paciente utilizou também danazol sem sucesso, e apresentou resposta clínica somente após ter sido submetida a múltiplas sessões de plasmaferese, ocorrendo inclusive resolução de extenso angioedema na mucosa do trato gastrointestinal.Acquired angioedema is caused by different drugs and lymphoproliferative diseases, and rarely it has also been related to the presence of auto-immune disorders. We report the case of a 47 year old female with systemic lupus erythematosus (SLE and severe cutaneous involvement who developed recurrent localized angioedema of the face, including lips and eye lids, upper limbs, and thorax, not associated with urticaria, and with reduced levels of C1 esterase inhibitor. Treatment with antimalarials, glucocorticoids, and pulse therapy with methylprednisolone associated with azathioprine did not improve her condition. The patient was also unsuccessfully treated with danazol, and she only showed clinical response after several sessions of plasmapheresis, including resolution of the extensive edema of the gastrointestinal tract.

  1. Daño cerebral adquirido: percepción del familiar de las secuelas y su malestar psicológico

    Directory of Open Access Journals (Sweden)

    Elena López de Arróyabe Castillo

    2013-01-01

    Full Text Available Este estudio tuvo como objetivo evaluar la percepción que el familiar tiene de los problemas de la persona afectada por un daño cerebral adquirido y su asociación a sus propios síntomas de estrés, depresión y duelo. Participaron 223 familiares (cuidadores principales. Se desarrolló un inventario de 36 secuelas percibidas estructuradas en 6 factores: déficits cognitivos y sensoriales, cambios de personalidad, dependencia, actividad disminuida, trastornos emocionales y autoconciencia y percepción social disminuida. Los resultados mostraron que las secuelas percibidas tienen relativamente poco impacto en el malestar psicológico del familiar. Las secuelas con mayor asociación a los síntomas psicológicos fueron dependencia, asociada significativamente a sentimientos actuales de duelo, y la actividad disminuida, que se asocia a las respuestas involuntarias de estrés de aproximación y alejamiento. Estos datos contradicen la literatura que sostiene la relación causal entre secuelas percibidas y síntomas en los familiares, sugiriendo otro tipo de factores implicados.

  2. Pie plano-valgo adquirido

    OpenAIRE

    Albiol Ferrer, Josep Maria; Giralt de Veciana, Enrique; Marugán de los Bueis, Montse; Novel Martí, Virginia; Ogalla, José Manuel; Zalacain, Antonio

    1990-01-01

    Es la patología del pie que tiene mayor incidencia durante la infancia. Su recuperación eficaz, además de precisar un largo período de tratamiento, requiere un diagnóstico precoz. Durante la lactancia, a partir de los tres meses, y después, durante la infancia, hasta los tres años aproximadamente, una gruesa y blanda capa de panlculo adiposo determina una configuración que rellena la bóveda y ofrece una falsa imagen de pie plano.

  3. Hipotireoidismo adquirido tratado como obesidade exógena: a importância do controle do crescimento Acquired hypothyroidism treated as exogen obesity: the importance of growth follow-up

    Directory of Open Access Journals (Sweden)

    Mariana Porto Zambon

    2009-03-01

    Full Text Available OBJETIVO: Demonstrar a importância da interpretação do acompanhamento pôndero-estatural de crianças e adolescentes obesos DESCRIÇÃO DO CASO: Menina de 12 anos e 11 meses encaminhada a um ambulatório terciário para acompanhamento de obesidade e dislipidemia. Referia ganho de peso a partir de oito anos, negava fazer atividade física e possuía alimentação adequada. Relatava obesidade na família do pai. Ao exame, bom estado geral, diminuição da pilificação e mixedema generalizados, pele ressecada e áspera. Peso com percentil entre 90 e 97, índice de massa corpórea (IMC acima do percentil 97 e estatura abaixo do canal de crescimento. EXAMES LABORATORIAIS: T4: 0,04ng/ dL, TSH: >100uUI/mL, colesterol total: 326mg/ dL, HDL colesterol: 34mg/ dL, LDL colesterol: 45mg/ dL, triglicérides: 1599mg/ dL, glicemia em jejum: 81mg/dL e hemograma com discreta anemia normocrômica e normocítica. Fez-se o diagnóstico de hipotireoidismo e introduziu-se hormônio tireoidiano com boa resposta. A paciente trouxe 23 medidas prévias de peso e estatura, mostrando comprometimento de estatura e aumento de peso não valorizado. COMENTÁRIOS: A análise dos gráficos de crescimento é fundamental para o acompanhamento de todas as crianças e adolescentes, principalmente aquelas com sobrepeso e obesidade. A desaceleração da curva de crescimento em altura sugere doença associada; neste caso, o hipotireoidismo adquirido.OBJECTIVE: To show the value of using the follow-up growth charts in clinical evaluation of obese children and adolescents. CASE DESCRIPTION: A 12 years and 11 months-old girl referred to a tertiary out-patient clinic to evaluate obesity and lipid abnormalities. She had weight gain since eight years old, had no physical activity and followed adequate eating habits. Obesity was referred in father's family. In physical examination, she looked well, with lack of body hair, generalized mixedema, dry and rough skin. Weight was between

  4. Efecto de un programa de actividad físico deportiva sobre la salud de personas con daño cerebral adquirido en fase crónica

    OpenAIRE

    Pérez Rodríguez, Marta

    2017-01-01

    El Daño Cerebral Adquirido (DCA) es una discapacidad con gran incidencia en nuestra sociedad, de gran complejidad y grandes costes sanitarios, siendo las dos etiologías más comunes el ictus y el traumatismo craneoencefálico (TCE). El resto de etiologías de lesión cerebral son menos frecuentes, aunque generan demandas de recuperación similares. Los avances en el área de la neurorrehabilitación han logrado establecer una propuesta eficaz para la mejora funcional sobre los diferentes déficits fí...

  5. Il cavo orale nel paziente obeso

    OpenAIRE

    Faggella, Antonella

    2008-01-01

    Le condizioni di sovrappeso ed obesità anche in età evolutiva sono aumentate negli ultimi decenni al punto che, secondo l'Organizzazione Mondiale della Sanità, sono diventate un problema di salute pubblica in tutti i Paesi occidentali. Questa tesi è nata nell’obiettivo di individuare caratteristiche odontostomatologiche in pazienti affetti da obesità; il gruppo campione(80 pazienti, età media 10,5 anni) è stato suddiviso in due sottogruppi: sottogruppo A comprendente 54 pazienti affetti da...

  6. Sepse por Staphylococus aureus resistente à meticilina adquirida na comunidade no sul do Brasil Sepsis due to community-acquired methicillin-resistant Staphylococcus aureus in southern Brazil

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    Luciane Cristina Gelatti

    2009-08-01

    Full Text Available Staphylococcus aureus resistente à meticilina foi inicialmente descrito como um típico microrganismo adquirido em infecções nosocomiais. No entanto, nos últimos anos Staphylococcus aureus resistente à meticilina adquirido na comunidade é causa de infecções de pele e tecidos moles, mas infecções graves como pneumonia e sepse podem ocorrer. Este relato descreve um caso de sepse em criança, complicado com pneumonia secundária a lesão em partes moles por Staphylococcus aureus resistente à meticilina adquirido na comunidade no Sul do Brasil. O paciente foi atendido em Unidade de Emergência com história de ferimento provocado por trauma em membro inferior que evoluiu para celulite, pneumonia e sepse.Methicillin-resistant Staphylococcus aureus was initially described as a typical microorganism acquired in nosocomial infections. However, over recent years, community-acquired methicillin-resistant Staphylococcus aureus has been a cause of skin and soft-tissue infections. Serious infections such as pneumonia and sepsis can also occur. This report describes a case of sepsis in a child that was complicated by pneumonia secondary to soft tissue lesions that were due to community-acquired methicillin-resistant Staphylococcus aureus in southern Brazil. The patient was attended at the Emergency Unit with a history of injury caused by lower-limb trauma that evolved to cellulitis, pneumonia and sepsis.

  7. Utilidad de un programa de rehabilitación neuropsicológica de la memoria en daño cerebral adquirido (Usefulness of a Program of Neuropsychological Rehabilitation of Memory in Acquired Brain Damage

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    Carlos José De los Reyes-Aragón

    2013-12-01

    Full Text Available RESUMEN: Este estudio evaluó la utilidad de un programa de rehabilitación cognitiva y funcional de memoria para pacientes con daño cerebral adquirido. Diez participantes con deterioro cognitivo leve o moderado participaron en el estudio, cinco de ellos asistieron durante cuatro meses a un programa semanal de rehabilitación, mientras que los otros cinco no recibieron intervención neuropsicológica. Los resultados mostraron que el grupo de rehabilitación mejoró la puntuación en la Escala de Memoria de Wechsler III. De igual forma, se encontró que la puntuación en la escala de fallos de memoria de la vida diaria solo mejoró en el grupo que recibió rehabilitación. Los resultados sugieren que el programa de rehabilitación de la memoria resulta útil en el tratamiento de las secuelas tanto cognitivas como funcionales resultantes del daño cerebral adquirido. ABSTRACT: This study evaluated the usefulness of a cognitive and functional rehabilitation of memory program for patients with acquired brain injury. Ten participants with mild- to -moderate cognitive impairment participated in the study; five of them for four months attended a weekly rehabilitation program, while the other five did not receive any neuropsychological intervention. The results showed that the rehabilitation group improved the score in the Wechsler III Memory Scale. Similarly, it was found that the score on the memory scale of failure of the daily life only improved in the group that received rehabilitation. The results suggest that memory rehabilitation program is useful in the treatment of both cognitive and functional sequels resulting from acquired brain damage.

  8. Variação inter-individual nos níveis de bilirrubina: o papel dos factores genéticos e adquiridos

    OpenAIRE

    Rodrigues, Carina; Vieira, Emília; Santos, Rosário; Carvalho, João; Santos-Silva, Alice; Elísio, Costa; Bronze-da-Rocha, Elsa

    2011-01-01

    A bilirrubina é um pigmento biliar que deriva principalmente do catabolismo da hemoglobina. É um marcador bioquímico de doenças hepáticas e hematológicas e tem vindo a ser alvo de interesse devido à sua capacidade antioxidante. O objectivo deste trabalho foi avaliar a contribuição de vários factores para a variação da concentração da bilirrubina sérica na população portuguesa. Foi analisado o contributo dos polimorfismo genéticos no promotor do gene UGT1A1 (c.-41_40...

  9. Conocimientos previos acerca de métodos anticonceptivos y su relación con conocimientos adquiridos después de una intervención educativa con simulador

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    María Neyfeth Posada Morales

    2015-01-01

    Full Text Available Introducción. El objetivo de este trabajo es relacionar conocimientos previos (pre-saberes acerca de métodos anticonceptivos con los conocimientos adquiridos (saberes, después una intervención educativa con simulador.Método. Es un estudio realizado con 295 adolescentes escolarizados que cursan noveno, décimo y undécimo en una institución educativa pública. Es de tipo descriptivo. El proceso estuvo compuesto por tres fases; en la primera se midió conocimientos o saberes previos acerca de métodos anticonceptivos, mediante un cuestionario auto-informado; en la segunda se definió los contenidos y actividades de intervención para mejorar los conocimientos previos, y en la tercera fase de post-intervención educativa, se reevaluó los saberes adquiridos con el simulador. Resultados. Se detectó que los pre-saberes en métodos anticonceptivos son deficientes independientemente de la edad y la escolaridad, lo cual requiere planeación, desarrollo y evaluación de la estrategia de aprendizaje colectivo y cooperativo mediante talleres. En cuanto a los post-saberes, se obtuvo una calificación de deficientes a regulares, en el caso del condón masculino, mientras que el reconocimiento de métodos modernos como parche, anillo vaginal, dispositivo intrauterino, entre otros, se dio gracias al contacto directo con el simulador.Conclusiones. Se recalca que a pesar de las  diferencias de edad y escolaridad, no hubo hallazgos relevantes que demostraran diferencias de conocimiento. En los pre-saberes, se encontró niveles de conocimiento deficientes sobre métodos anticonceptivos. El uso de simuladores como herramienta de aprendizaje demostró eficacia en los talleres; en cuanto a los simuladores posibilitan la ruptura de la barrera cognitiva, dado que el adolescente, en este caso, puede explorar y adquirir conocimiento al interaccionar con el objeto de aprendizaje.

  10. Saberes docentes na prática do professor de música do Projeto SESC Cidadão

    OpenAIRE

    Araújo, José Magnaldo de Moura

    2016-01-01

    Este trabalho apresenta, discute e analisa como se constituem e de que forma se articulam os saberes docentes de um professor de música atuante no projeto social SESC Cidadão. Para alcançar tal objetivo foi realizada uma pesquisa que teve os seguintes objetivos específicos: verificar aspectos gerais acerca da formação cultural-profissional do professor atuante no SESC Cidadão; compreender de que forma os saberes adquiridos na formação “formal” do professor têm subsidiado sua ação pedagógica n...

  11. Técnicas de rehabilitación neuropsicológica en daño cerebral adquirido: ayudas de memoria externas y recuperación espaciada

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    Karol Gutiérrez Ruíz

    2009-01-01

    Full Text Available Este artículo tuvo como objetivo realizar una revisión de las técnicas de recuperación espaciada y de ayudas de memoria externas, para la rehabilitación de personas con daño cerebral adquirido. Inicialmente se expusieron las alteraciones cognitivas y funcionales comunes en personas con daño cerebral y, posteriormente se describieron cada una de las técnicas, indicando en qué consiste cada una de ellas y mostrando los resultados de las investigaciones revisadas. Se determinó que la principal utilidad de las técnicas de recuperación espaciada y ayudas de memoria externas fue en el tratamiento de dificultades de memoria, aunque sólo en algunas ocasiones se evaluaron mejorías en medidas neuropsicológicas. La utilización de ayudas de memoria externas fue la técnica que en más ocasiones demostró ganancias en funcionalidad y mantenimiento a largo plazo.

  12. Avaliação dos resultados tardios da operação de derivação cavo-pulmonar bidirecional, no tratamento paliativo de cardiopatias congênitas com câmara ventricular única Assessment of late results of bidirecional cavopulmonary shunt on paliative treatment of congenital heart disease with functional isolated ventricular chamber

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    Miguel Angel Maluf

    1994-06-01

    Full Text Available No período de março de 1990 a janeiro de 1994, 17 pacientes com idades de 1 a 13 anos (média: 7 anos, portadores de cardiopatias congênitas com câmara ventricular única funcionante, foram submetidos a operação de derivação cavo-pulmonar bidirecional. Nove pacientes tinham atresia tricúspide (AT, 7 do tipo lb, 1 tipo le e 1 tipo Mb. Cinco pacientes tinham dupla via de entrada ventricular tipo ventrículo direito (DVEVD; 2 com comunicação interventricular(CIV múltipla+hipoplasiado VD; 1 com atresia pulmonar com septo interventricular íntegro (APc/SIVI. Nove (52,9% pacientes tinham operações paliativas prévias. A operação foi realizada com auxílio da circulação extracorpórea (CEC em 12 (70,5% casos e mediante derivação do fluxo sangüíneo da veia cava superior (VCS para o átrio direito (AD em 5 (29,5% casos. Em todos os casos a VCS foi anastomosada à artéria pulmonar direita (APD, interrompendo o fluxo sangüíneo para o pulmão, fechando a valva pulmonar e ligando a derivação de Blalock-Taussig pérvio. Houve 3 (17,6% óbitos no pós-operatório imediato (POI e 2 (14,2% no pós-operatório tardio (POT. Doze (70,5% pacientes estão em acompanhamento clínico, com um tempo de evolução de 2 a 46 meses. Um paciente foi submetido ao 2º tempo da operação, tunelizando a veia cava inferior (VCI para a APD, com sucesso. A avaliação do fluxo da derivação cavo-pulmonar bidirecional está sendo realizada pela ecodopplercardiografia e ressonância nuclear magnética e a perfusão pulmonar mediante cintilografia radioisotópica. A indicação do 2º tempo da operação obedece à própria evolução clínica e avaliação da saturação arterial durante a cicioergometria. A derivação cavo-pulmonar bidirecional permite uma adaptação progressiva do fluxo venoso para o pulmão, diminuindo a sobrecarga de volume do ventrículo, preparando o paciente para a derivação venosa total.From March 1990 to January 1994, 17

  13. Análises químicas e organolépticas de vinhos de mesa brancos e tintos adquiridos no comércio Characteristics of Brazilian white and red wines

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    Odette Zardetto de Toledo

    1963-01-01

    Full Text Available São apresentados os resultados organolépticos e analíticos de 15 amostras de vinhos de mesa brancos e 15 de tintos, adquiridos no comércio de Campinas, em 1960. Foram encontradas poucas amostras com características inteiramente satisfatórias, notando-se, principalmente, deficiências de clarificação e de filtração. Das 15 marcas de vinhos brancos, só três se apresentaram perfeitamente brilhantes, e sete, ligeira ou completamente turvos. Nos tintos, em geral, foi maior a turbidez. Verificou-se, também, a presença, entre os brancos, de vinhos com acidez volátil acima do limite permitido pela legislação brasileira. Foi notada a ausência de anidrido sulfuroso total e livre. Os resultados dos outros componentes mostraram-se, todavia, bastante satisfatórios. Foram ainda observados o comprimento insuficiente das rôlhas para garantir a boa conservação do vinho, e a desuniformidade das garrafas quanto a tipo, forma, capacidade e côr.Fifteen hrands of white and 15 of red wines were collected from groceries for analysis and flavor tests. Very few samples were satisfactory. Most of the wines had been poorly clarified and filtered. Only three of the 15 samples of white wines were brilliant; seven were classified as slightly cloudy or cloudy. Cloudiness was higher among the red wines. Two samples of the white wines had a high volatile acidity, above the limit permitted by the Brazilian regulation. Lack af free and total sulfur dioxide was observed. As far as the other wines constituents are concerned, all analysed samples were satisfactory. The corks utilized were generally shorter than it is desirable to seal the bottles satisfactorily. Also, the bottles were not uniform in type, shape, capacity, and color.

  14. O papel do Fator de Necrose Tumoral Alfa (TNF-alfa no processo de erosão óssea presente no colesteatoma adquirido da orelha média The role of Tumor Necrosis Factor -Alpha (TNF- alpha in bone resorption present in middle ear cholesteatoma

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    Rodrigo Faller Vitale

    2007-02-01

    Full Text Available O colesteatoma adquirido da orelha média causa erosão óssea, com altas taxas de morbidade e mortalidade. O TNF-alfa (TNF-alfa lambda uma das principais citocinas envolvidas neste processo. OBJETIVO: Avaliar o papel do TNF-alfa na reabsorsão óssea e a ação dele no colesteatoma. MATERIAL E MÉTODOS: Foi realizado um levantamento e uma revisão crítica da literatura. RESULTADOS: Todos os autores estudados concordam com a importância do TNF-alfa no processo de reabsorção óssea presente no colesteatoma e com o grau de destruição observado. Diferentes trabalhos demonstraram que o TNF-alfa é capaz de provocar erosão óssea, através de diferentes vias de ação. Ele pode estimular a diferenciação e a maturação dos osteoclastos ou, ainda, agir na matriz óssea expondo-a à ação dos osteoclastos. Existe a possibilidade de inibir a ação do TNF-alfa, diminuindo seus efeitos e prevenindo a perda óssea em doenças como a artrite reumatóide. Não existe, entretanto, trabalhos específicos em colesteatoma. Não existe consenso sobre a sua localização. Estas diferenças, provavelmente, ocorrem devido à distribuição dos receptores. CONCLUSÃO: O TNF-alfa, presente no colesteatoma promove a reabsorsão óssea, juntamente com outras citocinas (RANKL e IL-1, estando relacionado com a presença de complicações.Cholesteatoma may cause bone erosion, with high morbidity and mortality rates. Tumor Necrosis Factor -Alpha (TNF-a is one of the main cytokines involved in this process. Our goal was to evaluate the role of TNF-a in Bone Resorption and its effect on cholesteatoma. MATERIAL AND METHODS: analysis and critical literature review. RESULTS: Different studies have demonstrated that TNF-a is capable of causing bone erosion. It may stimulate the differentiation and maturation of osteoclasts or it may act on the bone matrix, exposing it to the action of the osteoclasts. It is possible to inhibit TNF-a, reducing its effects and prevent

  15. Factores de riesgo para el desarrollo de infección de vías urinarias por microorganismos productores de betalactamasas de espectro extendido adquiridos en la comunidad, en dos hospitales de Bogotá D.C., Colombia

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    Mariana Pineda-Posada

    Full Text Available Abstract Objetivo: Determinar factores de riesgo para infección urinaria por microorganismos productores de betalactamasas de espectro extendido (BLEE adquirida en la comunidad en pacientes adultos. Material y método: Estudio de casos y controles, en el período comprendido entre enero de 2012 a mayo de 2015, en dos hospitales de Bogotá D.C., Colombia. Pareo por edad, año del aislamiento, microorganismo y género. Se excluyeron pacientes con antecedente de infección por un microorganismo productor de BLEE en el último mes e infección urinaria asociada al cuidado de la salud. Resultados: Se analizaron 555 pacientes: 185 casos y 370 controles. 462 pacientes (83,2% de la Fundación Clínica Shaio y 93 (16,8% del Hospital Santa Clara. Factores de riesgo identificados: Infección urinaria recurrente (OR 2,13 con IC de 1,48 a 3,07, enfermedad renal crónica (OR 1,56, IC del 95% de 1,07 a 2,27, uso previo de antibióticos (OR 3,46, IC del 95% de 2,48 a 5,35, hospitalización reciente (OR 3,0, IC del 95% de 1,96 a 2,45, diabetes mellitus (OR 1,61 con IC del 95% de 1,06 a 2,45 e infección urinaria alta (OR 2,64 con IC del 95% de 1,61 a 4,32. Conclusiones: Los factores de riesgo para microorganismos productores de BLEE adquiridos en la comunidad fueron en orden de frecuencia: antecedente de antibioticoterapia reciente, hospitalización previa, presencia de infección urinaria alta, así como los antecedentes de infección urinaria recurrente, enfermedad renal crónica y diabetes mellitus, lo que concuerda con los principales hallazgos descritos en la literatura mundial.

  16. Imunoexpressão da citoqueratina 16 e do antígeno nuclear Ki-67 no colesteatoma adquirido da orelha média Expression patterns of cytokeratin 16 and the nuclear antigen Ki-67 in acquired middle ear cholesteatoma

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    Celina S. B. Pereira

    2002-08-01

    Full Text Available Introdução: Ocolesteatoma da orelha média é caracterizado pela presença de epitélio escamoso estratificado queratinizado nesta cavidade, causando destruição óssea e podendo levar a complicações. Algumas substâncias como a citoqueratina 16 e o Ki-67, marcadores de proliferação celular, vêm sendo utilizadas para estudar essa doença. A CK 16 é um filamento protéico, situado no citoplasma das células epiteliais, característico de epitélios hiperproliferativos. O Ki-67 é um antígeno nuclear que aparece nas células em estágio de proliferação. Objetivo: O objetivo deste trabalho foi estudar a imunoexpressão da CK 16 e do Ki-67 no colesteatoma adquirido. Forma de estudo: Clínico prospectivo. Material e Método: Foram colhidas amostras de colesteatoma de 31 pacientes submetidos à cirurgia otológica, sendo 20 adultos e 11 crianças, no período de 1998 e 2000. Essas amostras foram submetidas à análise histológica e imuno-histoquímica para estudo da expressão da CK 16 e do Ki-67 na matriz do colesteatoma. Resultado: A análise dos resultados mostrou a presença da CK 16 nas camadas suprabasais da matriz do colesteatoma e, do Ki-67, na camada basal, estendendo-se para as camadas suprabasais e, inclusive, para a camada apical da matriz. A reação aos anticorpos anti-CK 16 e Ki-67 foi heterogênea. A correlação entre a CK 16 e o Ki-67 suprabasal com variáveis morfológicas, como acantose do epitélio e hiperplasia da camada basal formando cones epiteliais em direção à perimatriz, foi positiva e significativa. Também houve relação positiva e significativa entre a CK 16 e o Ki-67 suprabasal e apical. Conclusão: Esses resultados permitem concluir que o colesteatoma tem características hiperproliferativas, expressando a CK 16 e o Ki-67 na sua matriz.Introduction: Cholesteatomas of the middle ear are characterized by the presence of stratified squamous epithelium in this cavity presenting with highly invasive

  17. Preliminary study of community-acquired Staphylococcus aureus infection in Manaus Hospital, Amazonia Region, Brazil Estudo preliminar das infeccões por Staphylococcus aureus na comunidade de um Hospital em Manaus, Região do Amazonas, Brasil

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    Jesus M. Egido

    2003-12-01

    Full Text Available Methicillin resistant Staphylococcus aureus is considered a public health problem with a strong potential for dissemination and high rates of morbidity and mortality. In this study we describe bacteriological and epidemiological characteristics of Staphylococcus aureus in Manaus (Amazon region. During the one-year study period (2000-2001, sixteen cases of acute pyogenic multiple abscess were evaluated. Community-acquired S. aureus was identified as causative agent in 10 (62.5% patients. The strains tested with antimicrobials by discs diffusion method, exhibited a high rate of sensitivity to cephalexin (100%, erythromycin (90%. Oxacillin-susceptible Staphylococcus aureus was 90%. No isolate was resistant to Vancomycin. To our knowledge, no series of community-acquired Staphylococcus aureus in Manaus hospital has been published. Our partial results showed a high rate of antimicrobial sensitivity among community-acquired Staphylococcus aureus in the hospital of Tropical Medicine Institute of Manaus, Amazon Region.O Staphylococcus aureus resistente a meticilina é considerado como um problema na saúde publica por seu grande potencial de disseminação e altas porcentagens de morbidade e mortalidade. No estudo descrevemos as características bacteriológicas e epidemiológicas do Staphylococcus aureus na cidade de Manaus. No período de um ano (2000-2001 avaliou-se dezesseis casos de abscessos piogênicos múltiplos. Em 10 (62,5% doentes o agente causal foi identificado como Staphylococcus aureus adquirido na comunidade O estudo das bacterias isoladas frente aos diferentes antimicrobianos, seguindo o método de difusão em disco, mostrou boa sensibilidade a cefalexina (100% e eritromicina (90%. Noventa porcento dos Staphylococcus aureus isolados foram sensíveis ao oxacilina. Nenhum dos isolados mostrou ser resistente a Vancomicina. Não temos informações sobre publicações dos Staphylococcus aureus adquiridos na comunidade em hospitais de Manaus

  18. Adesione batterica e fungina a materiali protesici del cavo orale

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    Fabrizio Cavallini

    2005-12-01

    Full Text Available Introduction.The microbial adhesion to dental material was studied employing a acrylic resin and representative microrganisms. Method. Bacterial suspensions (about 108 CFU/ml were mixed to dental material with different surface finishes. Bacterial counts were carried out before and after 1 hour at 37°C.A tube without dental material was used as control.The same experiments were also performed at the presence of saliva. Results. Candida albicans demonstrated to adhere to free energy material at an incidence 64% while Staphylococcus aureus and Streptococcus oralis showed more adhesive properties for roughness material (34 and 52% respectively. The presence of saliva influenced the adhesiveness to all materials with the exception of S. aureus that increased from 20 to 29% the number of cells on the surface of free energy material. Conclusion. The surface finishes appeared did not significantly influence the adhesion of microrganisms to this material.

  19. Načrtovan porod na domu

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    Todorović, Tamara; Takač, Iztok

    2017-01-01

    Izhodišča: Porod na domu je sicer star toliko kot človeštvo, pa vendar v veliki večini srednje in visoko razvitih držav prevladuje mnenje, da so zaradi nepredvidljivosti zapletov porodnišnice najbolj varno okolje za rojevanje. Kljub temu obstaja peščica držav, v katerih je porod na domu integriran v sistem zdravstvenega varstva (npr. Nizozemska, Velika Britanija, Kanada). Pri porodih na domu ločimo nenačrtovane in načrtovane porode na domu, slednje pa lahko nadalje razdelimo še na porode s sp...

  20. A relevância do apoio social na velhice

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    Rosa Maria Lopes Martins

    2016-02-01

    Full Text Available O debate gerado em torno do envelhecimento e das respostas sociais de apoio aos cidadãos idosos, têm adquirido nos últimos anos e particularmente nas sociedades ocidentais, crescente actualidade e relevância. A notoriedade desta questão, encontra-se na centralidade que o tema tem tido no discurso político e social e na proliferação de iniciativas mais ou menos visíveis e mediáticas que têm como preocupação central questões ligadas a velhice e ao apoio social. Apesar de só a partir dos anos 70 o apoio social constituir um quadro teórico integrado e consistente, encontram-se já anteriormente inúmeros estudos ligados à psicologia (sobretudo a comunitária cujos contributos foram decisivos para o seu desenvolvimento. Marcos fundamentais no campo do apoio social foram também as investigações levadas a cabo por Caplan (1974, Cassel (1974 e 1979, Cobb (1976, Barrón (1996, Vaux (1988, Faria (1999, Vaz Serra (1999, e Matos e Ferreira (2000. O seu interesse deriva não só do facto de terem aberto caminho ao desenvolvimento e conceptualização deste constructo, mas porque a partir delas foi possível conhecer os efeitos sobre a saúde e bem-estar de diferentes tipos de relações, (relações intimas a integração social, passando pelo estudo das redes sociais nos seus aspectos estruturais e funcionais.

  1. Biometria, caracterização física e rendimento lipídico do fruto de Licania rigida Benth adquiridos no município de Pombal-PB

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    T. S. S. Almeida

    2015-12-01

    Full Text Available Resumo: Licânia rigida Benth, popularmente oiticica, é uma vegetação típica no sertão nordestino. Destaca-se pelo alto teor de óleos em seus frutos e boa produtividade mesmo em épocas de seca, sendo capaz de promover desenvolvimento social e econômico para a região, pela utilização industrial de tintas, vernizes, sabão, lonas e esmaltes finos. Portanto, objetiva-se no presente estudo determinar a biometria, parâmetros físicos e rendimento lipídico do fruto da oiticica. Os frutos foram colhidos, selecionados, sanitizados. Em seguida, utilizou-se um paquímetro para a realização da biometria dos frutos e então sofreram separação em exocarpo-mesocarpo, endocarpo e amêndoas. As amostras foram trituradas e armazenadas ate procedidas as análises. Para a determinação do pH e condutividade, utilizou-se cerca de 5g de cada amostra, acrescidos de 50mL de água destilada e homogeneização, por conseguintemente foi utilizado o peagâmetro digital e condutivímetro, respectivamente. Para a acidez total titulável (ATT, utilizou-se as amostras anteriores e titulou-se com NaOH 0,1N, usando fenolftaleína como indicador, até as amostras alcançarem pH de 8,1. Procedeu-se a determinação do teor lipídico pelo método de Sohlext, com 2 a 5 g das amostras e hexano como solvente. Os frutos apresentaram peso médio de 9g. A variação do pH para as diferentes amostra foi irrelevante, enquanto o exocarpo-mesocarpo apresentou maior condutividade, com 308,6 mScm-1, e o endocarpo foi evidenciado por apresentar maior ATT, com 16,8%. Obteve-se na amêndoa maior percentual lipídico, com rendimento médio de 43,0%. Diante da importância e alta rentabilidade lipídica do fruto, faz-se necessário desenvolvimento de metodologias para utilização dessa matéria-prima.Biometrics, physical characteristics and yield fruit of lipid Licania rigid Benth purchased in the municipality of Pombal-PBAbstract: Licania rigid Benth, popularly oiticica, is

  2. Aproximación a las unidades con significado en el campo de la informática adquirido por extensión metafórica en los diccionarios generales de inglés y español

    Directory of Open Access Journals (Sweden)

    María Teresa Ortego Antón

    2015-07-01

    Full Text Available En las últimas décadas la revolución científico-tecnológica ha dado lugar a la aparición de nuevos conceptos y, por ende, de infinidad de denominaciones. El conocimiento experto suele producirse en inglés, si bien surge la necesidad de traducirlo a otras lenguas como el español. Durante el transvase interlingüístico, las unidades con significados adquiridos por extensión metafórica pueden convertirse en un obstáculo para los usuarios, que acuden a los diccionarios generales bilingües en busca de soluciones, a pesar de que ésta no es la única herramienta ni la más aconsejable. En consecuencia, en el presente trabajo nos centramos en el estudio de dichas unidades en el campo de la informática, con el objetivo de obtener una aproximación del tratamiento que de dichos significados se ofrece en dos diccionarios generales bilingües de inglés y de español. De los resultados que se desprendan esperamos obtener datos relevantes que incidan en una implementación de la información recogida en las obras de referencia.

  3. Influencia do indice de massa corporal no equilibrio e na configuracao plantar em obesos adultos

    Directory of Open Access Journals (Sweden)

    Liu Chiao Yi

    2014-01-01

    Full Text Available INTRODUÇÃO: A obesidade é uma doença crônica degenerativa multifatorial que pode levar a alterações do sistema musculoesquelético, como mudança do centro de gravidade e sobrecarga mecânica sobre os membros inferiores. OBJETIVOS: Correlacionar o índice de massa corporal (IMC com o equilíbrio corporal e verificar associação entre o IMC e a configuração plantar. MÉTODOS: Foram avaliados 30 obesos, de ambos os gêneros, com IMC maior ou igual a 30 Kg/m². Inicialmente, os voluntários foram submetidos às avaliações de medidas antropométricas a fim de calcular o valor do IMC. Em seguida, foram submetidos ao teste de equilíbrio corporal estático Balance Error Scoring System (BESS e a plantigrafia para a identificação da impressão plantar. Por meio do método de Viladot, os voluntários foram classificados em grupos: pé plano (GPP, pé cavo (GPC e pé neutro (GPN. A correlação entre as variáveis IMC e BESS foi calculada por meio do coeficiente de correlação linear de Pearson e associação entre o IMC e a configuração plantar foi realizada por meio da análise de variância (Anova. Para todas as análises, nível de significância considerado foi p < 0,05. RESULTADOS: Os valores da correlação entre o IMC e o BESS foram r = - 0,1 e p = 0,59. Os valores da associação do IMC entre GPN - GPP; GPN - GPC; GPP - GPC foram respectivamente: p = 0,76; p = 0,001; p = 0,07. CONCLUSÃO: O índice de massa corporal de adultos obesos não influencia o equilíbrio corporal, porém influencia na configuração plantar.

  4. Controvérsias na fibrose cística: do pediatra ao especialista

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    Ribeiro Jose Dirceu

    2002-01-01

    Full Text Available Objetivos: nos últimos 70 anos, a fibrose cística emergiu da obscuridade para o reconhecimento como a mais importante doença hereditária, potencialmente letal, incidente na raça branca. Embora seja uma doença genética, na qual o defeito básico acomete células de vários órgãos, nem todos os indivíduos expressam respostas clínicas na mesma intensidade. Várias manifestações clínicas, principalmente pulmonares e digestivas, podem ocorrer durante a vida dos pacientes fibrocísticos. O objetivo deste artigo é propiciar ao pediatra geral uma visão atualizada dos principais assuntos referentes à fibrose cística. Fontes dos dados: revisão sistemática e atualizada em fonte de dados oficial (Medline. Síntese dos dados: foram revisados 79 artigos sobre fibrose cística, de periódicos internacionais, colocando, de modo atual e crítico, os principais eventos relacionados com a incidência, a fisiopatogenia, as manifestações clínicas, o diagnóstico e o tratamento da fibrose cística. Conclusões: apesar de não existir cura para essa doença, muitos conhecimentos novos sobre a etiologia e a fisiopatologia, adquiridos nas duas últimas décadas, propiciaram uma nova abordagem para o tratamento da fibrose cística. A compreensão dos mecanismos básicos da doença pulmonar, bem como das manifestações digestivas na fibrose cística, decorrente dos conhecimentos de pesquisas recentes, tem sido a chave para o aumento da sobrevida e a melhora da qualidade de vida dos pacientes.

  5. A case of familial transmission of community-acquired methicillin-resistant Staphylococcus aureus carrying the lnu(A gene in Santa Fe city, Argentina Caso de transmisión familiar de Staphylococcus aureus resistente a la meticilina adquirido en la comunidad portador del gen lnu(A en la ciudad de Santa Fe, Argentina

    Directory of Open Access Journals (Sweden)

    Emilce de los A Méndez

    2012-12-01

    Full Text Available Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA is increasingly recognized as an important pathogen causing skin and soft tissue infections as well as necrotizing pneumonia. We describe a case of familial transmission of CA-MRSA between a 6-month-old boy and his mother in Santa Fe City, Argentina. Both isolates showed an identical antimicrobial susceptibility profile, carried type IV SCCmec and harboured the pvl and the lnu(A genes. Isolates showed indistinguishable SmaI-PFGE patterns confirming their genetic relationship. These results corroborate the intrafamilial transmission of CA-MRSA and might associate this strain with the repetitive events of furunculosis within the family.Staphylococcus aureus resistente a la meticilina adquirido en la comunidad (SARM-AC es reconocido como un patógeno importante que causa infecciones de piel y partes blandas y neumonía necrotizante. Describimos un caso de transmisión familiar de SARM-AC entre un nino de 6 meses de edad y su madre en la ciudad de Santa Fe, Argentina. Ambos aislamientos mostraron idéntico perfil de sensibilidad a los antimicrobianos, tenían el SCCmec tipo IV, y contenían los genes pvl y lnu(A. Los aislamientos presentaron patrones de SmaI-PFGE indistinguibles entre sí, lo cual confirmó su relación genética. Estos resultados corroboran la transmisión intrafamiliar de SARM-AC; asimismo, este aislamiento podría asociarse con los eventos repetitivos de furunculosis en la familia.

  6. Surgical correction of strabismus in Lambert-Eaton myasthenic syndrome: case reports Correção cirúrgica do estrabismo na síndrome de Lambert-Eaton: relato de dois casos

    Directory of Open Access Journals (Sweden)

    Fernanda Teixeira Krieger

    2009-02-01

    Full Text Available Lambert-Eaton myasthenic syndrome is a rare and acquired autoimmune disorder. We describe two female patients with medial rectus paresis as the only ocular manifestation. After a unilateral medial rectus recession and lateral rectus resection procedure, both patients recovered normal adduction. To our knowledge, this is the first report of surgery for extraocular muscle paresis in Lambert-Eaton myasthenic syndrome.A síndrome de Lambert-Eaton é um distúrbio autoimune raro e adquirido. Apresentamos duas pacientes com paresia do reto medial como única manifestação ocular. Após retrocesso do reto lateral e ressecção do reto medial, unilateral, ambas as pacientes apresentaram normalização da adução. Até onde sabemos, este é o primeiro relato de cirurgia para paresia do reto medial na síndrome de Lambert-Eaton.

  7. Parametri za procena na kvalitetot na polietilenska i na polipropilenska ambalaza i na gumeni zatvoraci nameneti za farmacevtski preparati

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    Liljana Ugrinova

    2002-03-01

    Full Text Available Napraven e pregled na parametrite za procena na kvalitetot na polietilenska i na polipropilenska ambalaza i na gumeni zatvoraci nameneti za farmacevtski preparati. Za procena na kvalitetot na ispituvaniot materijal bea izvrseni fizicki, hemiski i bioloski ispituvanja spored postapkite dadeni vo Ph. Eur., DIN i spored DIN ISO standardite. Baranjata za kvalitet na ovoj vid ambalaza propisani spored Ph. Eur., DIN i DIN ISO standardite se razlikuvaat vo odnos na predvidenite parametri za fizicki, za hemiski i za bioloski ispituvanja. Isto taka, propisani se i razlicni granici na dozvoleno otstapuvanje na oddelni parametri.

  8. Trabajo social sanitario y daño cerebral adquirido

    OpenAIRE

    Ruiz-Prados Víbora, Lucía

    2014-01-01

    La figura del profesional del trabajo social sanitario, ocupa un puesto rezagado en la sociedad, cuyo desconocimiento ocasiona la pérdida de sus conocimientos aplicados a su trabajo. Este trabajo fundamenta, la razón de su utilidad e importancia. Por un lado, centrándose más específicamente en el ámbito de la sanidad, resaltando la figura del/la profesional en cuanto a la continuidad de cuidados ante el alta hospitalaria y, posteriormente, haciendo hincapié en todo lo que respe...

  9. UMA REFLEXÃO SOBRE A EXPERIÊNCIA VIVIDA NA UNIVERSIDADE: A TRANSIÇÃO DE LÍDER PARA CONTRIBUIDOR INDIVIDUAL

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    Fabiula Meneguete Vides da Silva

    2014-06-01

    Full Text Available Buscamos através deste trabalho, apresentar uma reflexão sobre as experiências vividas na universidade na transição de líder para contribuidor individual, enfocando os aprendizados adquiridos. A abordagem fenomenológico-hermenêutica de van Manen (1990 foi utilizada a fim de retomar os principais temas desta experiência. Seis ex-gestores universitários emprestaram suas experiências vivenciadas em universidades pertencentes à Associação Catarinense das Fundações Educacionais (ACAFE, através das entrevistas em três tempos preconizadas por Seidman (1998, realizadas entre maio de 2009 e março de 2010. O processo de transição vivido na universidade possibilitou-lhes aprendizagem e mudanças nos seus comportamentos. Os dados revelados por meio das experiências dos professores revelam temas úteis para a compreensão da experiência vivida nas transições nas universidades, trazendo, assim, contribuições para pensarmos políticas de recursos humanos, a fim de minimizarmos os aspectos negativos vividos pelos professores, como também para ampliarmos as pesquisas que levem em conta a temática da transição de professores nas universidades.

  10. AVALIAÇÃO DO IMPACTO DA CAPACITAÇÃO PROFISSIONAL ADMINISTRADA NA PREFEITURA DE MANAUS POR MEIO DA APLICAÇÃO DO MODELO IMPACT

    Directory of Open Access Journals (Sweden)

    Diego Melo Dias

    2016-06-01

    Full Text Available A capacitação profissional é uma arma poderosa na busca pelo desenvolvimento das competências humanas no trabalho. O foco em treinamento e desenvolvimento tornou-se indispensável ao alcance da excelência na prestação de serviços. Na administração pública os órgãos responsáveis pelo aperfeiçoamento profissional são as Escolas de Governo, que atuam junto aos funcionários públicos na melhoria da máquina estatal, que tem o dever de prestar serviços públicos de qualidade. Sendo assim, o estudo objetiva avaliar o impacto da capacitação profissional voltada para o servidor na Prefeitura de Manaus. Para isso a análise se deu por meio da adaptação do Modelo IMPACT de avaliação do treinamento, aplicado junto aos servidores egressos de atividades de capacitação promovidas pela Escola de Serviço Público da Prefeitura de Manaus (ESPI. Os resultados sugerem que há forte impacto positivo da capacitação administrada pela ESPI nas atividades laborais dos servidores, no entanto, o suporte dado pelas chefias ao treinamento necessita de ajustes para que possa proporcionar um melhor aproveitamento dos conhecimentos e habilidades adquiridos pelos servidores em prol de suas instituições.

  11. At NA2

    CERN Multimedia

    1977-01-01

    One of the NA2 calorimeter sections is moved in. The NA2 calorimeter was divided in two halves, to the left and the right of the beam, each half consisting of sheets of passive high Z material interleaved with blades of plastic scintillators. The photo shows on the right, the upstream 'electron' module with eleven lead plates for a total radiation length of 20.

  12. Levantamento etnobotânico de plantas medicinais na comunidade quilombola Carreiros, Mercês – Minas Gerais

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    Flávia M. C. Ferreira

    2014-09-01

    Full Text Available O objetivo do trabalho foi identificar as espécies medicinais utilizadas pela comunidade quilombola Carreiros, bem como traçar o perfil social das famílias desta comunidade. Para tanto, foram realizadas entrevistas semiestruturadas da comunidade, sendo um representante de cada família. Para fins de registro foram coletados dois exemplares de cada espécie medicinal identificada, os quais foram conservados na forma de exsicatas e mantidos no Laboratório de Ecologia do IF Sudeste MG – Campus Rio Pomba. As mulheres aparentemente desempenham importante papel social e estão bastante envolvidas no conhecimento das plantas medicinais. Nota-se, que o conhecimento existente foi adquirido de forma empírica e éevidente entre as famílias a preocupação em repassar os conhecimentos tradicionais sobre o uso das plantas medicinais aos jovens. Dentre as principais espécies utilizadas pela comunidade estão: Citrus Sinensis L., Psidium guajava L., Leonurus sibiricus L., Citrus Limonia (Osbeck, Carica sp., Vernonia condensataBacker, Sechuium edule (Jacq. Sw, Sansevieria trifasciata Prain, Malpighia glabra L., e Saccharum zofficinarum L..

  13. Sensoriamento remoto multifonte aplicado na detecção do fitoplâncton em águas interiores

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    Rejane E. Cicerelli

    2015-03-01

    Full Text Available Florações de fitoplanctôn podem constituir em riscos à saúde humana e biota aquática, sendo necessários o monitoramento da comunidade fitoplanctônica e a adoção de mecanismos visando à prevenção de sua ocorrência. Neste contexto métodos tradicionais de monitoramento podem ser mais efetivos se complementados por abordagens que utilizam as propriedades ópticas dos pigmentos fitoplanctônicos por meio do Sensoriamento Remoto. Com o objetivo de avaliar o potencial de dados espectrais multifonte na detecção remota do fitoplâncton, foi selecionada uma área de estudo no reservatório de Nova Avanhandava, SP, caracterizada por intensa atividade agrícola no seu entorno. Para esta análise foram adquiridos dados hiperespectrais em campo e imagens multiespectrais Modis e RapidEye, os quais foram relacionados a variáveis limnológicas indicadoras do comportamento fitoplanctônico; clorofila a e ficocianina. Os resultados mostram que imagens multiespectrais permitem uma avaliação da biomassa fitoplanctônica pela clorofila a; contudo, para ficocianina, pigmento fitoplanctônico diagnóstico da presença de cianobactérias, dados mais refinados são necessários, tais como os hiperespectrais.

  14. Polarization dependence of Na* + Na* associative ionization revisited

    NARCIS (Netherlands)

    Meijer, H.A.J.; Meulen, H.P. v.d.; Morgenstern, R.; Hertel, I.V.; Meyer, E.; Witte, R.

    1986-01-01

    The dependence of the associative ionization process Na 3 2P3/2 + Na 3 2P3/2 → Na2+ + e- on the polarization of the laser light used for Na excitation was independently investigated in Utrecht and Berlin. The purpose of this paper is to clarify discrepancies between two other earlier experimental

  15. Procedimento educativo na epilepsia infantil Educational procedure in infantile epilepsy

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    Paula Teixeira Fernandes

    2001-06-01

    Full Text Available A epilepsia é uma condição neurológica crônica que afeta o comportamento do paciente e traz dificuldades psico-sócio-culturais. O trabalho em grupos visa melhorar a interação pais-filhos, através de informações adequadas sobre a epilepsia. O objetivo do presente trabalho foi, através dos grupos de apoio (procedimento educativo, esclarecer aspectos relacionados à epilepsia e avaliar a eficácia destes grupos na identificação e na melhora das variáveis psicológicas. Foram aplicados 36 protocolos (pré e pós-testes que avaliaram sentimentos, crenças e comportamentos dos pais e filhos. Foram observados sentimentos de mágoa e medo, tristeza e rejeição, que foram associados a superproteção e falta de limites. Depois do grupo, 91,6% dos pais relataram ter adquirido mais conhecimento sobre a epilepsia, associando muitas das dificuldades com a falta de informação e a presença de crenças irracionais. Conclui-se que orientação sobre a epilepsia, o uso de medicamentos, os aspectos psicológicos, sociais e comportamentais, melhoram a adaptação à doença. Por isso, a importância dos grupos na desmistificação de crenças, identificação de relações parentais e prevenção de dificuldades comportamentais.Epilepsy is a neurologic disorder, which affects the patient's behaviour and carries strong psychological, social and cultural difficulties. Group-work improves the interaction parent-child, through appropriate explanations regarding the epilepsy. The purpose of this study was to give adequate information about epilepsy through support groups (educational procedure and to assess the efficacy of these groups in identifying psychological aspects. Protocols were applied to 36 parents before and after the sessions, with questions concerning feelings and beliefs about epilepsy as well as parent-child interactions. As the main results, the following feelings were observed: fear, frightening and anxiety, sadness and rejection

  16. NAKUPOVANJE NA SPLETU

    OpenAIRE

    Visenjak, Monika

    2013-01-01

    Nakupovanje na spletu je prihodnost poslovanja. Za podjetja pomeni manjše stroške, lažje prilagajanje tržnim pogojem. Hitreje lahko razvijajo odnose in analizirajo uporabnike, saj jim je dan dostop o nakupnih podatkih uporabnika. Za potrošnike je nakupovanje na spletu možnost hitrega, preprostega in učinkovitega nakupovanja od doma ali pisarne. Pomembno je, da se seznanijo z vsemi informacijami in pogoji spletnih trgovin, saj se lahko le tako izognejo nezadovoljstvu ob nakupu v spletni trgovi...

  17. Alterações na audiometria de tronco encefálico em mulheres adultas com hipotireoidismo subclínico

    Directory of Open Access Journals (Sweden)

    Figueiredo Lília Cristiane M. S.

    2003-01-01

    Full Text Available A correlação entre perda auditiva e distúrbios adquiridos da glândula tireóide tem sido tema de interesse há muito tempo na Medicina. Diversos trabalhos foram dedicados à investigação audiológica de pacientes com hipotireoidismo, mas poucos autores abordaram a forma subclínica desta doença utilizando a audiometria de tronco encefálico (ABR. OBJETIVO: Avaliar se ocorrem ou não alterações na ABR em mulheres normoacúsicas com hipotireoidismo subclínico não tratado quando comparadas a mulheres sem doença endócrina. DESENHO DO ESTUDO: Prospectivo clínico. MATERIAL E MÉTODO: Uma série de 16 pacientes foi analisada com ABR e seus resultados foram relacionados aos do grupo-controle análogo em sexo e idade. RESULTADOS: Houve diferença significativa (p<0,05 nas médias das latências absolutas das ondas III (p=0,039 e V (p=0,006 e dos intervalos interpicos I-III (p=0,017, III-V (p=0,044 e I-V (p=0,002 entre os dois grupos, mostrando que as medidas destas latências foram significativamente maiores no grupo do hipotireoidismo. CONCLUSÃO: Na condição de hipotireoidismo subclínico, antes mesmo de haver qualquer anormalidade nos limiares psicoacústicos, já poderá ser observado comprometimento na condução nervosa ao longo das vias auditivas no tronco encefálico, como demonstrado pela avaliação com ABR.

  18. Transição paradigmática na educação médica: um olhar construtivista dirigido à aprendizagem baseada em problemas

    Directory of Open Access Journals (Sweden)

    Pedro Henrique Netto Cezar

    Full Text Available A necessidade de mudança no projeto político-pedagógico das escolas médicas vem sendo discutida, especialmente, em resposta ao amadurecimento da reflexão acerca do perfil do egresso desejado. Reconhece- se que o ensino médico tradicional - centrado, prioritariamente, na transmissão de conhecimentos - tem levado à formação de profissionais despreparados para responder aos agravos à saúde mais encontrados na população. Para tentar mudar esse panorama, vêm sendo privilegiadas, a partir das Diretrizes Curriculares Nacionais do Curso de Graduação em Medicina do Ministério da Educação (MEC, as metodologias ativas de ensino-aprendizagem, entre as quais se destaca a Aprendizagem Baseada em Problemas (ABP, que permite maior participação do estudante na construção do conhecimento. Tal encaminhamento é realizado a partir da inclusão do graduando na comunidade desde os primeiros períodos do curso médico, promovendo a contextualização dos constructos teóricos adquiridos por meio de buscas individuais e do compartilhamento do conhecimento. Desta forma, cria-se uma parceria entre instituições de ensino superior, serviços de saúde e a comunidade, a partir da qual se espera formar médicos com uma visão integral do ser humano, comprometidos com a sociedade.

  19. O Partido Nacional Renovador: a nova extrema-direita na democracia portuguesa The PNR and the new far-right in Portuguese democracy

    Directory of Open Access Journals (Sweden)

    José Mourão da Costa

    2011-10-01

    Full Text Available O Partido Nacional Renovador (PNR representa o mais recente desenvolvimento na história das organizações e partidos de extrema-direita em Portugal. Fundado na viragem do século, veio preencher um espaço órfão de representação partidária e romper com a tradição universalista e multirracial do nacionalismo lusitano. Assumindo um papel aglutinador entre o movimento associativo afecto �� extrema-direita, o partido constituiu-se como a expressão portuguesa de uma nova linhagem de partidos nacional-populistas na Europa Ocidental. Contudo, apesar de ter adquirido uma visibilidade sem precedentes entre os seus antecessores na era democrática, o seu desempenho no plano eleitoral não feriu a tese da marginalização da direita radical portuguesa.The Partido Nacional Renovador (National Renewal Party represents the latest development in the history of far-right organizations and parties in Portugal. Established at the turn of the century, it occupied a niche unclaimed by any other party, breaking with the universalist and multiracial tradition of Portuguese nationalism. Taking on a unifying role within the far-right associative movement, the party established itself as the Portuguese manifestation of a new lineage of nationalist-populist parties in Western Europe. However, despite having acquired a visibility that was unprecedented among its predecessors in the democratic era, its performance on the electoral stage did not alter the marginal status of the Portuguese far-right.

  20. Riso na epilepsia

    Directory of Open Access Journals (Sweden)

    Edymar Jardim

    1967-06-01

    Full Text Available São estudados três casos de síndrome convulsiva temporal, com manifestações concomitantes de riso na sua fase inicial. As características principais foram a imotivação e á incoercibilidade do riso. Esses sintomas desapareceram com o uso de anticonvulsivantes.

  1. Efeito de diferentes doses de radiação gama na solução de quitosana

    Directory of Open Access Journals (Sweden)

    Ingrid Moraes

    2017-09-01

    Full Text Available Quitosana é um polissacarídeo adquirido da desacetilização da quitina, existente em insetos e invertebrados marinhos. Possui ação fungistática e não causa reações de toxicidade ao organismo humano. Ela é utilizada como revestimento de alimentos, prolongando a vida pós-colheita e melhorando a aparência do produto. O objetivo deste trabalho foi avaliar o efeito de diferentes doses de radiação gama na solução de quitosana. As amostras foram analisadas quanto à cor onde foi observado que a radiação gama induz a mudança da intensidade e na tonalidade da solução de quitosana. A análise de MEV mostrou que as partículas do pó de quitosana possuem formatos irregulares, e as amostras irradiadas apresentaram grânulos menores dando uma aparência mais fina e dispersa. A solução também foi analisada quanto à viscosidade e foi visto que a irradiação alterou a viscosidade da solução, deixando-a menos viscosa. Assim, dentre as doses, a de 5 kGy foi a que apresentou alteração mais relevante às características da solução e a futuras aplicações da mesma.

  2. Atletismo na escola : realidade?

    OpenAIRE

    Sampaio, Alessandro Oliveira de

    2012-01-01

    O correr, saltar, lançar e arremessar são elementos básicos do atletismo, sendo fundamentais para o ser humano, devido ao favorecimento do desenvolvimento físico e motor. Sendo um dos conteúdos principais do desporto e da educação física escolar, foi realizado um estudo relacionado à prática do atletismo na escola, na qual o objetivo desta pesquisa foi verificar se entre os professores de educação física da rede pública de ensino fundamental de 5ª a 8ª séries, da cidade satélite de Samambaia ...

  3. Preparing for NA4

    CERN Multimedia

    CERN PhotoLab

    1977-01-01

    Here, in one of the EF workshop, Albert Duchêne works on a pretty piece of mechanics. A few others await to be attended on the left. There are indications that the pipes were meant to house the carbon target (subdivided in eight sections) to be installed inside the toroid magnet of the NA4 experiment. The external strips were designed to possibly correct the magnetic field (???).

  4. Estratégias de ensino-aprendizagem na enfermagem: análise pela Escala de Coma de Glasgow Estrategias de enseñanza y aprendizaje en enfermería: análisis por la Escala de coma de Glasgow Teaching-learning strategies in nursing: analysis using the Glasgow Coma Scale

    Directory of Open Access Journals (Sweden)

    Ana Beatriz Pinto da Silva Morita

    2009-09-01

    Full Text Available Usando como tema a Escala de Coma de Glasgow (ECGl, este estudo objetivou analisar e verificar a retenção do conhecimento frente às estratégias de ensino-aprendizagem e autoaprendizado oferecidas, e verificar o grau de conhecimento adquirido neste processo e a possível associação entre ser ou não aluno que trabalha na enfermagem. Estudo descritivo de abordagem quantitativa. Participaram 62 alunos regularmente matriculados no primeiro semestre do 4º ano de enfermagem. As estratégias de ensino-aprendizagem utilizadas foram: aula expositiva com diapositivos e videoteipe e texto-base. Dos participantes, 41,9% eram trabalhadores na enfermagem; 61,3% informaram ter cuidado de pacientes com alteração do nível de consciência, com predomínio no grupo em que trabalha. Houve incremento estatisticamente significante no percentual de acerto após a aula expositiva e o videoteipe, não havendo alteração no resultado após o autoaprendizado. Não houve diferença no grau de conhecimento adquirido entre os grupos.Usando como tema la Escala de Coma de Glasgow (ECGl, este estudio objetivó analizar y verificar la retención del conocimiento frente a las estrategias de enseñanza aprendizaje y auto aprendizaje ofrecidas; y, verificar el grado de conocimiento adquirido en ese proceso y la posible asociación entre ser o no alumno que trabaja en enfermería. Estudio descriptivo de abordaje cuantitativo. Participaron 62 alumnos regularmente matriculados en el primer semestre del 4ºaño de enfermería. Las estrategias de enseñanza aprendizaje utilizadas fueron: clase expositiva con diapositivas y videotape y texto base. De los participantes, 41,9% eran trabajadores de enfermería; 61,3% informaron haber cuidado de pacientes con alteración del nivel de conciencia, con predominio en el grupo que trabaja. Hubo un incremento estadísticamente significativo en el porcentaje de aciertos después de la clase expositiva e videotape, no hubo alteración en

  5. The CERES / NA45 experiment

    CERN Multimedia

    Laurent Guiraud

    2000-01-01

    Ceres is one of the second generation heavy ion experiments at CERN's SPS. It is dedicated to the study of electron-positron pairs in relativistic nuclear collisions. NA45 is one of the seven experiments (NA44, NA45, NA49, NA50, NA52, WA97/NA57 and WA98) involved in CERN's Heavy Ion programme which provided evidence for the existence of a new state of matter, the quark-gluon plasma. In this state, quarks, instead of being bound up into more complex particles such as protons and neutrons, are liberated and roam freely. Theory predicts that this state must have existed at about 10 microseconds after the Big Bang, before the formation of matter as we know it today.

  6. Envolvimento pulmonar na polimiosite

    Directory of Open Access Journals (Sweden)

    Direndra Hasmucrai

    2010-07-01

    Full Text Available Resumo: Introdução: A polimiosite (PM e a dermatomiosite são classificadas como miopatias inflamatórias idiopáticas. O envolvimento pulmonar por PM é pouco frequente, estando descrito na literatura em cerca de 10% de casos.Os autores apresentam um caso de uma mulher de 75 anos, com queixas de febre, perda ponderal, artralgias, mialgias e diminuição simétrica e proximal da força muscular com impotência funcional dos membros superiores e inferiores, com início um mês antes do internamento. Apresentava infiltrados pulmonares na telerradiografia de tórax. Após estudo exaustivo estabeleceu-se o diagnóstico de envolvimento pulmonar na forma de pneumonia organizativa por PM. Efectuou-se corticoterapia e terapêutica com micofenolato com melhoria clínica, analítica e radiológica. Conclusão: Neste caso, foi a alteração na telerradiografia de tórax numa doente sem sintomatologia respiratória que levou ao estudo exaustivo até ao diagnóstico de PM, realçando mais uma vez a importância da telerradiografia no rastreio de patologias de outros foros. Abstract: Introduction: Polymyositis and dermatomyositis are classified as idiopathic inflammatory myopathies. Interstitial lung disease is rare and is described in the literature in about 10% of cases.The authors describes a case of 75 year old woman presenting with one month evolution of fever, weight loss, arthralgia, myalgia and symmetric and proximal muscle weakness of upper and lower limbs. Nonspecific interstitial changes was found in chest X-ray. After exhaustive study, the diagnosis of pulmonary envolvement in the form of organizing pneumonia by polymyositis, was established. Glucocorticoids and mycophenolate were prescribed with good clinical, analytical and radiological outcome. Conclusion: In this case, it was the changes in the chest X-ray in a patient without respiratory symptomatology, that conducted to exhaustive study to polymyositis diagnosis, enhancing once again the

  7. Comprometimento pulmonar na leptospirose

    Directory of Open Access Journals (Sweden)

    Jorge Eduardo Manhães de Carvalho

    1992-03-01

    Full Text Available Em 23 pacientes com leptospirose apresentando comprometimento pulmonar, internados no Hospital Universitário Antônio Pedro da XJFF, Niterói, hemoptise e hemoptóicos foram observados em 21,7% e 30,4%, respectivajnente. Gasometria arterial revelou hipoxemia e hipocapnia na maioria dos casos. Radiografia de tórax em 15 pacientes mostrou comprometimento alveolar em 60%, comprometimento intersticial-reticular em 6%, padrão misto (alveolar e intersticial em20%e ausência de alterações radiológicas em 14%. A necrópsiade 13 pacientes mostrou edema, congestão e hemorragia nos pulmões em 100% dos casos. A hemorragia foi focal em 46% e difusa em 54% dos casos. Houve formação de membrana hialina em 30% e trombos de fibrina em 46% dos pulmões estudados, o que estabelece o diagnóstico da coagulação intravascular disseminada e a ocorrência da síndrome de angústia respiratória na leptospirose.

  8. Measurement of exchangeable sodium: 22Na or 24Na

    International Nuclear Information System (INIS)

    Smith, T.; Edmonds, C.J.

    1987-01-01

    A case is made for the use of 22 Na in low activities in preference to 24 Na for routine diagnostic estimation of exchangeable sodium, and is based chiefly on considerations of availability, cost and radiation dosimetry. A method in which only 37 kBq (1 μCi) 22 Na is administered orally is shown to be sufficiently accurate and to possess distinct advantages in terms of cost and convenience with a committed radiation dose no greater than that for a measurement using 24 Na. (author)

  9. The NA27 trigger

    International Nuclear Information System (INIS)

    Bizzarri, R.; Di Capua, E.; Falciano, S.; Iori, M.; Marel, G.; Piredda, G.; Zanello, L.; Haupt, L.; Hellman, S.; Holmgren, S.O.; Johansson, K.E.

    1985-05-01

    We have designed and implemented a minimum bias trigger together with a fiducial volume trigger for the experiment NA27, performed at the CERN SPS. A total of more than 3 million bubble chamber pictures have been taken with a triggered cross section smaller than 75% of the total inelastic cross section. Events containing charm particles were triggered with an efficiency of 98 +2 sub(-3)%. With the fiducial volume trigger, the probability for a picture to contain an interaction in the visible hydrogen increased from 47.3% to 59.5%, reducing film cost and processing effort with about 20%. The improvement in data taking rate is shown to be negligible. (author)

  10. Na Cauda do Cometa

    Science.gov (United States)

    Voelzke, M. R.

    2009-01-01

    Quando viam um cometa, os antigos gregos imaginavam uma estrela com uma vasta cabeleira. Não à toa, a palavra deriva do termo koma, que significa cabelo. Constituídos por fragmentos de gelo e gases, os cometas possuem um núcleo sólido, que pode ter vários quilômetros de diâmetro, e uma cauda que sempre aponta na direção contrária ao Sol, devido aos ventos solares. Graças à aparência de pontos luminosos em movimento (ao contrário de outros astros, que parecem estáticos), esses corpos celestes foram interpretados por diferentes povos com muito misticismo, inspirando mitos tanto de boas-novas como de maus presságios. Conheça algumas dessas histórias:

  11. NA48 prototype calorimeter

    CERN Multimedia

    1990-01-01

    This is a calorimeter, a detector which measures the energy of particles. When in use, it is filled with liquid krypton at -152°C. Electrons and photons passing through interact with the krypton, creating a shower of charged particles which are collected on the copper ribbons. The ribbons are aligned to an accuracy of a tenth of a millimetre. The folding at each end allows them to be kept absolutely flat. Each shower of particles also creates a signal in scintillating material embedded in the support disks. These flashes of light are transmitted to electronics by the optical fibres along the side of the detector. They give the time at which the interaction occurred. The photo shows the calorimeter at NA48, a CERN experiment which is trying to understand the lack of anti-matter in the Universe today.

  12. A ENGENHARIA NA ESCOLA

    Directory of Open Access Journals (Sweden)

    Valéria Pelizzer Casara

    2015-04-01

    Full Text Available Este projeto teve por objetivo principal mostrar às jovens do ensino médio, como as áreas de exatas e de engenharia podem estar inseridas em situações rotineiras por elas vivenciadas e incentivá-las para ingressarem nessas áreas. O projeto foi executado na escola de ensino Médio Nelson Horostecki na cidade de Chapecó, Santa Catarina. Mostrou-se de forma simples que as áreas de exatas e de engenharia têm aplicações práticas nas nossas vidas. No desenvolvimento do projeto, realizaram-se oficinas na escola cujo tema principal abordado foi o processo de fabricação do chocolate, visto que o mesmo é um produto muito apreciado pelas adolescentes. Dentro dessa temática, foram trabalhadas as questões que envolvem conhecimentos das áreas de exatas e de engenharia, mais especificamente a Engenharia Ambiental. O projeto auxiliou na formação cidadã e também na escolha profissional das meninas. Muitas das alunas participantes nunca haviam tido contato direto com alunos graduandos de cursos na área das exatas. Mais ainda, este projeto oportunizou a aproximação da universidade com a comunidade externa. Palavras-chave: Extensão Universitária, Ciências Exatas e Engenharia, Chocolate, Oficinas.   Engineering in the school Abstract: The main objective of this project was to show high school female students how the exact sciences and engineering can be included in their routine situations encouraging them to entering in these areas. The project was carried out at the Nelson Horostecki High School in Chapecó, Santa Catarina State, Brazil. It was showed in a simple manner how exact sciences and engineering have practical applications in our lives. Workshops were conducted in the school during the execution of the project in which the main subject was the chocolate manufacturing process, since chocolate is a product greatly appreciated by the young female people. Within this matter, the activities were performed using the knowledge of

  13. Investigation on U - O - Na, Pu - O - Na and U,Pu - O - Na phase diagrams

    International Nuclear Information System (INIS)

    Pillon, S.

    1989-03-01

    The thermochemical interaction between the nuclear fuel (uranium and plutonium mixed oxides) and the sodium has been investigated and particularly the three phase diagrams: U - O - Na; Pu - O - Na; U,Pu - O - Na. High temperature neutron diffraction, microcalorimetry and powder X-ray diffraction were used for the characterization of the compounds synthetized. This study allowed to complete the knowledge about each of these diagrams and to measure some physical and thermal properties on the compounds. The limits on the modelization of the fuel-sodium interaction are discussed from the results of the UO 2 - Na reaction [fr

  14. Simulation of Ventricular, Cavo-Pulmonary, and Biventricular Ventricular Assist Devices in Failing Fontan.

    Science.gov (United States)

    Di Molfetta, Arianna; Amodeo, Antonio; Fresiello, Libera; Trivella, Maria Giovanna; Iacobelli, Roberta; Pilati, Mara; Ferrari, Gianfranco

    2015-07-01

    Considering the lack of donors, ventricular assist devices (VADs) could be an alternative to heart transplantation for failing Fontan patients, in spite of the lack of experience and the complex anatomy and physiopathology of these patients. Considering the high number of variables that play an important role such as type of Fontan failure, type of VAD connection, and setting (right VAD [RVAD], left VAD [LVAD], or biventricular VAD [BIVAD]), a numerical model could be useful to support clinical decisions. The aim of this article is to develop and test a lumped parameter model of the cardiovascular system simulating and comparing the VAD effects on failing Fontan. Hemodynamic and echocardiographic data of 10 Fontan patients were used to simulate the baseline patients' condition using a dedicated lumped parameter model. Starting from the simulated baseline and for each patient, a systolic dysfunction, a diastolic dysfunction, and an increment of the pulmonary vascular resistance were simulated. Then, for each patient and for each pathology, the RVAD, LVAD, and BIVAD implantations were simulated. The model can reproduce patients' baseline well. In the case of systolic dysfunction, the LVAD unloads the single ventricle and increases the cardiac output (CO) (35%) and the arterial systemic pressure (Pas) (25%). With RVAD, a decrement of inferior vena cava pressure (Pvci) (39%) was observed with 34% increment of CO, but an increment of the single ventricle external work (SVEW). With the BIVAD, an increment of Pas (29%) and CO (37%) was observed. In the case of diastolic dysfunction, the LVAD increases CO (42%) and the RVAD decreases the Pvci, while both increase the SVEW. In the case of pulmonary vascular resistance increment, the highest CO (50%) and Pas (28%) increment is obtained with an RVAD with the highest decrement of Pvci (53%) and an increment of the SVEW but with the lowest VAD power consumption. The use of numerical models could be helpful in this innovative field to evaluate the effect of VAD implantation on Fontan patients to support patient and VAD type selection personalizing the assistance. Copyright © 2015 International Center for Artificial Organs and Transplantation and Wiley Periodicals, Inc.

  15. Exploring Collaborative and Community Based Planning in Tourism Case Study Sitia-Cavo Sidero Project

    OpenAIRE

    Katsouli, Penelope

    2007-01-01

    The present paper has explored the policy planning and development in emerging tourism settings in Sitia. Comprehensively, this study, in the name of sustainable development, focused on the extent of collaborative and community-based planning. For that reason exploratory research has been used; the context and the structure of this paper aimed to uncover the socially constructed reality of Sitia's stakeholders, within the dynamic environment, and respond to and questions. Therein significant ...

  16. Valores na escola

    Directory of Open Access Journals (Sweden)

    Menin Maria Suzana De Stefano

    2002-01-01

    Full Text Available Neste texto pretende-se discorrer sobre valores morais na escola e suas implicações para a formação de professores. Para tanto discutir-se-á, em primeiro lugar, e brevemente, o que são valores morais, ou éticos, e como a escola pode situar-se em relação a eles. Em seguida, serão relatadas algumas observações a respeito de valores de professores e práticas daí decorrentes. São comentados resultados de pesquisa que ilustram a transmissão de valores de forma doutrinal e a educação moral e cívica tal como realizada na ditadura militar, e, por outro lado, a posição relativista e/ou de laissez-faire que certas escolas podem adotar, metodologicamente, sobre a educação em valores. Finalmente, defender-se-á a idéia de que é necessária uma discussão sobre valores pelos diversos membros da escola e uma opção por uma metodologia para ensiná-los, seja os professores, em sua formação inicial e continuada, seja os alunos. A teoria de desenvolvimento moral de Jean Piaget será apresentada como uma referência possível para a educação em valores. Exemplos de situações escolares de conflito de valores entre direção, pais e alunos são discutidas para ilustrar como uma escola pode adotar um procedimento democrático de educação em valores, que se apresenta como um terceiro caminho possível de educação moral nas escolas, além das posições doutrinárias ou relativistas.

  17. CONTABILIDADE DE CUSTOS COMO FERRAMENTA GERENCIAL APLICADA A ATIVIDADE HOTELEIRA: ESTUDO DE CASO APLICADO NA REGIÃO DAS MISSÕES – RS

    Directory of Open Access Journals (Sweden)

    Luis Adriano Rodrigues

    2014-06-01

    Full Text Available Levando em consideração o aumento contínuo do turismo na região das Missões- RS, a formação do preço de venda na prestação de serviço, tem sido um dos maiores problemas para a rede hoteleira. Este trabalho foi realizado através de estágio supervisionado tendo como premissa básica a importância da contabilidade de custos, juntamente com a contabilidade gerencial para a formação do preço das diárias. A metodologia utilizada para realização do trabalho foi exploratória seguida de um estudo de caso, os dados foram extraídos de três entrevistas face a face com o sócio administrador e gerente, bem como relatórios adquiridos pelo contador. Neste contexto, após a análise e interpretação dos dados, conclui-se que o custo com a mão de obra é um dos fatores de maior significância quanto à geração de custos da empresa, tendo isso como base, a utilização da contabilidade de custos como ferramenta para a tomada de decisão juntamente com o contador são de extrema importância dentro de uma organização, juntos são capazes de a conduzirem de forma a obter os lucros desejados.

  18. ÍNDICE DE ESTRESSE HÍDRICO NA CULTURA DO ALGODÃO PARA FINS DO MANEJO DE IRRIGAÇÃO

    Directory of Open Access Journals (Sweden)

    Silvia Oliveira Dayube

    2017-02-01

    Full Text Available A cotonicultura é uma atividade praticada em grande escala no Brasil e tem grande importância social e econômica, sendo de fundamental importância o uso da irrigação Para um manejo de irrigação mais racional, o monitoramento dos parâmetros fisiológicos da planta se destaca como o controle ideal. Assim, objetivou-se verificar a variação do índice de estresse hídrico na cultura do algodão irrigado (determinado através de termômetro de infravermelho em função do déficit de umidade no solo. O estudo foi realizado em Fazenda, durante o período de 10 de março a 11 de junho do ano de 2015. Foram coletadas, amostras de solo indeformadas para determinação da umidade atual, conforme o Método-Padrão de Estufa. O cálculo do Crop Water Stress Index (CWSI foi feito em função dos valores de: temperatura foliar, umidade relativa do ar, e temperatura do ar adquiridos por meio de um termômetro infravermelho. Valores de CWSI variam de forma proporcional ao déficit de umidade no solo. A metodologia tem potencial para ser utilizada na realização do manejo de irrigação.

  19. A aposta na filosofia

    Directory of Open Access Journals (Sweden)

    Márcio Suzuki

    2011-12-01

    Full Text Available Para Hume, filosofar é uma atividade semelhante às demais ocupações humanas. A decisão que leva à atividade filosófica é menos resultado de uma argumentação teórica do que fruto de um cálculo prático, que é entendido como uma caça ou um jogo. O objetivo deste trabalho será o de mostrar que no jogo filosófico perde quem joga sério demais. A aposta na filosofia tem que passar pelo bom humor e pela diversão: uma resposta a Pascal?For Hume, philosophy is in itself neither more nor less important than other human activities. On the contrary, it can be explained from its resemblance with game and hunting. If one chooses to dedicate himself to philosophy, his decision is not the consequence of logical reasoning, but depends on practical evaluation, which has something to do with gambling. The following text tries to show that in philosophy, like in other games, the loser will be the one who plays too earnestly. The philosophical game requires good humour and some relaxation: Is this a good answer to Pascal's pari?

  20. VPLIV OSEBNOSTI NA STILE VODENJA

    OpenAIRE

    Vučak, Petra

    2009-01-01

    Nekatere naše vrline krasijo zlate lastnosti, druge pa kvarijo sivi odtenki. Če bi ljudje razumeli in spoznali svojo osebnost, ter osebnostne tipe drugih ljudi, bi se problemi pri komunikaciji občutno zmanjšali. Takrat bi namreč lažje uvideli, zakaj je nekdo reagiral na način, kot je ali zakaj je nekdo dejal to, kar je. Smisel tega je, da spoznamo svoje dobre lastnosti, ki jih lahko še bolj razvijemo, slabe pa poskušamo nadzorovati in tako zmanjšati njihov vpliv. Iskanje uspešnih in učink...

  1. SPOLNO NADLEGOVANJE NA DELOVNEM MESTU

    OpenAIRE

    Rubič, Gašper

    2016-01-01

    V diplomskem delu smo v uvodu predstavili problem spolnega nadlegovanja na delovnem mestu in predstavili podjetje TEKSTIL d.d. V nadaljevanju smo z anketo raziskali, ali problem spolnega nadlegovanja na delovnem mestu v obravnavanem podjetju obstaja in če, kako se nanj odziva okolje. V teoretičnem delu smo nadaljevali in predstavili definicijo spolnega nadlegovanja, ki je kakršna koli oblika nezaželenega verbalnega in neverbalnega ali fizičnega ravnanja spolne narave z učinkom ali nameno...

  2. Active transport of Na+ by reconstituted Na,K-ATPase

    International Nuclear Information System (INIS)

    Boldyrev, A.A.; Svinukhova, I.A.

    1987-01-01

    The ability of ATP, CTP, ITP, GTP, and UTP to support ouabain-sensitive accumulation of Na + by proteoliposomes with a reconstituted Na/K-pump was investigated. At a low [Na + ]/[K + ] ratio in the medium (20 mM/50 mM), a correlation is observed between the proton-accepting capacity of the nucleotide and its effectiveness as a substrate of active transport. To test the hypothesis of the importance of the presence of a negative charge in the 1-position of the purine (3-pyrimidine) base of the nucleotide for mutual transitions between the Na- and K-conformations of Na,K-ATPase they used two analogs of ATP: N 1 -hydroxy-ATP, possessing proton acceptor capacity, and N 1 -methoxy-ATP, in the molecule of which the negative charge is quenched by a methyl group. The first substrate supports active accumulation of Na + in proteoliposomes at the same rate as ATP, whereas the second substrate is relatively ineffective

  3. Beam monitoring at NA2

    CERN Multimedia

    1978-01-01

    Claus Goessling working on the beam Cerenkov counter of NA2. The muon beam enters from left the hall EHN2 and the last element of the beam transport. On background is the access door on the Jura side.

  4. Risbjerg: Historisk stemmeskred med NA

    DEFF Research Database (Denmark)

    Thomsen, Søren Risbjerg

    2007-01-01

    ANALYSE: NA flytter 12,3 pct. af stemmerne i majs meningsmålinger - historisk mange vælgere på en måned, skriver professor Risbjerg. Udgivelsesdato: 3. juni 2007......ANALYSE: NA flytter 12,3 pct. af stemmerne i majs meningsmålinger - historisk mange vælgere på en måned, skriver professor Risbjerg. Udgivelsesdato: 3. juni 2007...

  5. Na via do Behemoth

    Directory of Open Access Journals (Sweden)

    Gérard Rabinovitch

    2008-06-01

    Full Text Available O momento nazista permanece um enigma impensado de que a cultura contemporânea continua cativa. O autor levanta a hipótese de que a persistência desse enigma e seus estragos duráveis se devem à insistência dos pensamentos político, sociológico e filosófico em construírem o nazismo à luz da metáfora hobbesiana do Leviatã. Propõe retomar a questão do nazismo sob a perspectiva do Behemoth, antônimo do Leviatã. Para tanto, sugere a necessidade de retornar a Freud e à psicanálise, balizas de um possível novo pensamento do político que escrutine a destrutividade nazista. Propõe ainda sondar as homologias entre nazismo, corjas e máfias, com base na figura da " heroicização da violência" que lhes seria comum. E avança um modelo " econômico" : a quimera, suscetível de capturar o caráter heterotópico e heterocrônico de sua construção criminosa.The paths of Behemoth. The Nazi moment remains as the thoughtless enigma of which contemporary culture is still captive. The author raises the hypothesis where the persistency of this enigma and its durable damages are due to the insistence of the political, social and philosophical thoughts in building the Nazism at the view of the Hobbesian metaphor of Leviathan. It is here proposed to resume the Nazism matter under Behemoth's perspective, antonym to Leviathan. For such, it is suggested a necessity to look back at Freud and the psychoanalysis, structured by a possible new political thought which scrutinizes the destructivity of the Nazism. It is also here proposed to gaze at the homologies between Nazism, mafias and gangs, with a base in the figure of " violence as a heroically act" that are their common ground. The author also advances an economical model: the chimera susceptible to capture the heterotopic and heterochronic character of its criminal construction.

  6. Uso de Sistema de Informação Geográfica na Gestão do Marketing Mix: o caso de uma rede de calçados femininos

    Directory of Open Access Journals (Sweden)

    Rafaela Almeida Cordeiro

    2017-04-01

    Full Text Available O caso refere-se a uma rede de lojas de calçado feminino (Rede A que enfrenta problemas de estoque. A empresa não usa informações sobre clientes e localização do ponto de venda para renovar seu estoque, o que gera diminuição das vendas, excesso de produtos em algumas lojas e ruptura em outras, já que os modelos dos calçados adquiridos chegam a ser superiores (inferiores à demanda. Assim, o objetivo do trabalho é mostrar como as ferramentas de Sistema de Informação Geográfica (SIG podem ser aplicadas para solucionar o problema utilizando dados do Instituto Brasileiro de Geografia e Estatística (IBGE. Observou-se que a gestão do composto de marketing da Rede A não está alinhada ao seu público alvo e potencial. A análise forneceu insights para ações a serem tomadas em relação ao mix de produtos das lojas, à precificação, à localização dos pontos de venda e ao posicionamento da marca. As contribuições das ferramentas de geomarketing e geoinformação são fundamentais para as decisões de varejo. A técnica de geoprocessamento permite analisar fenômenos e distribuições aplicadas ao marketing na medida em que auxiliam na identificar de padrões, além de utilizar, simultaneamente, inúmeros bancos de dados. Este trabalho contribui para ampliar a discussão sobre as ferramentas SIG na área de marketing e para mostrar como ferramentas e dados gratuitos podem ser fortes aliados ao negócio.

  7. Avaliação da influência de características sensoriais e do conhecimento nutricional na aceitação do chá-mate

    Directory of Open Access Journals (Sweden)

    Helohá de Castro Barboza

    2018-01-01

    Full Text Available Resumo No âmbito empresarial, as estratégias de marketing voltadas para assuntos relacionados à nutrição têm sido a principal vantagem competitiva. Diante disso, o objetivo deste trabalho foi avaliar a influência de características sensoriais e do conhecimento nutricional na aceitação do chá-mate, visando identificar o comportamento do consumidor frente a este tipo de informação. Foi utilizado chá-mate tostado, tipo a granel, adquirido no comércio local e preparado de acordo com a recomendação descrita na embalagem. Para o teste afetivo de aceitação, foram recrutados 30 consumidores do produto. O recrutamento ocorreu por meio de um questionário abrangendo questões sobre o perfil dos consumidores, hábitos de consumo e disponibilidade para participar da pesquisa. Foram realizadas avaliações de aceitação sensorial em duas sessões (teste cego e com informação, utilizando-se uma escala hedônica de nove pontos, para avaliar os atributos cor, sabor, aroma e impressão global. Em relação ao perfil dos julgadores, 67% pertenciam ao sexo feminino, 50% relataram consumir chá-mate raramente e 37% afirmaram observar as informações nutricionais no rótulo. Houve diferença significativa para os atributos cor e sabor, entre as sessões cega e com informação. Pode-se concluir que o chá-mate apresentou boa aceitação pelos participantes e que o conhecimento nutricional influenciou positivamente na aceitação da bebida.

  8. Financiranje projekata na pomorskom dobru

    Directory of Open Access Journals (Sweden)

    Zoran Tasić

    2018-02-01

    Full Text Available Koncesije otvaraju vrlo osjetljiva politička, ekonomska i pravna pitanja u mnogim državama svijeta. Samo definiranje pojma koncesije često je komplicirana i ne sasvim jasna zadaća. OECD je prihvatila definiciju koncesije kao: ’’davanje prava privatnom trgovačkom društvu da može gospodarski upravljati određenom infrastrukturnim uslugama i za to zarađivati naknadu. Koncesionar dobija u posjed određene objekte (ali vlasništvo na tim objektima ostaje u rukama države te ih koristi u svrhu obavljanja određene djelatnosti ili usluge sukladno odredbama ugovora’’. Hrvatsko pravo definira koncesije načelno kao pravo stečeno temeljem ugovora o koncesiji, a sukladno uvjetima sadržanim u odluci o davanju koncesije (koju je donijelo odgovarajuće upravno tijelo, a u odnosu na pomorsko dobro, specifično, kao pravo državne vlasti da može dio pomorskog dobra, koje je inače dobro izvan pravnog prometa (res extra commercium, isključiti iz opće uporabe bilo dijelom ili u cijelosti, i dati ga fizičkoj ili pravnoj osobi na gospodarsko korištenje sukladno određenim prostornim planovima. Građevine i drugi objekti izgrađeni na pomorskom dobru čine njegov sastavni dio. Zakonom je jasno određeno da nikakva stvarna prava nisu dopuštena na pomorskom dobru, uključivo i na objektima izgrađenima na njemu. Projekti na pomorskom dobru često uključuju velike infrastrukturne projekte, razvoje luka i marina, koji iziskuju značajna financijska sredstva. Banke koje financiraju takve projekte zahtijevaju organiziran i transparentan zakonski okvir koncesija, slobodu ugovaranja, pravnu zaštitu svih strana uključenih u projekt (uključivo i mogućnost međunarodne arbitraže. (...

  9. Recikliranje plastenk na kreativen način

    OpenAIRE

    Pavlin, Suzana

    2017-01-01

    Plastenke, poleg ostalih plastičnih izdelkov, v zadnjih letih predstavljajo pravo katastrofo za okolje. Domnevamo, da se le redko kdo vpraša, kaj se zgodi z njo po tem, ko je iz nje zaužil še zadnjo kapljico vode. Plastenka je lahko kot večina ostalih komunalnih odpadkov ponovno uporabljena, reciklirana, sežgana ali odložena na deponijo. V primeru nespoštovanja Zakona o varstvu okolja pa pristane v naravi, pogosto v morju, kjer prav počasi razpada in negativno vpliva na celoten ekosistem. V d...

  10. All new for NA62

    CERN Multimedia

    Antonella Del Rosso

    2012-01-01

    This week sees the start of the first run of the new NA62 experiment. This will be a unique opportunity for the collaboration to test its new beam, new detectors and new data acquisition system before the physics run in 2014. Speaking to the Bulletin, the NA62 technical coordinator Ferdinand Hahn shares the many challenges that the various teams faced to be on time for beam. Ready, steady, start!   A Large Angle Veto detector (white) in place in the NA62 decay volume (blue). With components from almost all the detectors in place downstream of the decay point of the mother particles – the kaons – and of the KTAG detector that tags the kaons before they decay, NA62 is ready for its first technical run. This unique run will test all the equipment as well as the trigger and the data acquisition systems. “This year, we will have about five weeks of beam from the SPS before the long shutdown of all the CERN machines,” says Ferdinand Hahn, NA62 Technical Co-...

  11. Corpo e sexualidade na gravidez

    Directory of Open Access Journals (Sweden)

    Natalúcia Matos Araújo

    2012-06-01

    Full Text Available Estudo etnográfico que teve como objetivo compreender como as gestantes vivenciam os processos fisiológicos do seu corpo durante a gestação e a sua repercussão na sexualidade. A pesquisa envolveu sete mulheres residentes em bairro popular de São Paulo. Na coleta de dados, utilizou-se observação participante e entrevista com questões norteadoras. Os dados foram apresentados na forma de narrativa e posteriormente organizados nas categorias: Percebendo as transformações corporais; Convivendo com as mudanças no corpo; Sentimentos e sensações na vida sexual durante a gestação e imaginando o corpo e a sexualidade após a gestação. As mulheres referiram-se às transformações do corpo como desconfortos e expressaram a preocupação de que fossem definitivas. Expressaram o desejo de que, após o parto, o corpo volte a ser como era e que volte a sentir desejo sexual. O reconhecimento destes fatos constitui-se numa ferramenta primordial na adequação das práticas profissionais.

  12. gigapanorama of NA 62 cavern

    CERN Multimedia

    Brice, Maximilien

    2015-01-01

    The image shows the new rare Kaon decay experiment at CERN, called NA62. The NA62 experiment is 270 metres long and includes a 120-metre-long vacuum tank, shown here, housing several of the particle detectors. (Note: the experiment axis is a straight line, the curving of the tank is an optical effect of the photo.) Kaons are particles that decay into lighter elementary particles. The kaon decay processes are mostly well known, except for some very rare decay modes. For example, NA62 is investigating a rare decay predicted by the Standard Model in which a kaon decays into one pion and two neutrinos. This process occurs only once every 10 billion decays. The understanding of such ultra-rare decays are of great importance because they test the Standard Model in energy ranges not accessible by direct measurements. They are therefore complementary to the measurements at the LHC. ultra high definition on demand (photolab@cern.ch).

  13. Armas na escola: que fazer?

    Directory of Open Access Journals (Sweden)

    Raymundo de Lima

    2010-09-01

    Full Text Available

    Um aluno portava um revólver na sala de aula de uma escola de Maringá (O Diário, 30/07/2010. Ele pegou arma do pai, sem que este soubesse, para se proteger de garotos que o intimidavam. Trata-se de um caso isolado ou é hora de a escola tomar medidas preventivas? Semanas antes, tiros foram disparados dentro de uma faculdade da mesma cidade. O autor dos disparos está preso, e a faculdade tenta apagar as marcas com publicidade positiva na Tv. Em Campo Mourão, cidade a cerca de uma hora de Maringá, duas meninas foram mortas e enterradas na escola.

  14. OGLAŠEVANJE NA FACEBOOKU

    OpenAIRE

    Renko, Katica

    2013-01-01

    V magistrskem delu smo se seznanili z oglaševanjem na Facebooku. S pregledom gradiva, ki nam je ponujeno, smo preverili pogoje, načine, oblike … oglaševanja, ki pa smo jih s pregledom situacije v praksi preverili in dopolnili. Ob zaključku dela lahko rečemo, da je oglaševanje preko FB enostavnejše, cenejše, dostopnejše, omogoča nam ažurnost in samo komunikacijo z naslovniki, ki so potencialni kupci naših ponudb. Množični mediji nam omogočajo mnogotero obliko oglaševanja. Izbrana oblika ponuja...

  15. β decay of Na32

    Science.gov (United States)

    Mattoon, C. M.; Sarazin, F.; Hackman, G.; Cunningham, E. S.; Austin, R. A. E.; Ball, G. C.; Chakrawarthy, R. S.; Finlay, P.; Garrett, P. E.; Grinyer, G. F.; Hyland, B.; Koopmans, K. A.; Leslie, J. R.; Phillips, A. A.; Schumaker, M. A.; Scraggs, H. C.; Schwarzenberg, J.; Smith, M. B.; Svensson, C. E.; Waddington, J. C.; Walker, P. M.; Washbrook, B.; Zganjar, E.

    2007-01-01

    The β-decay of Na32 has been studied using β-γ coincidences. New transitions and levels are tentatively placed in the level scheme of Mg32 from an analysis of γ-γ and β-γ-γ coincidences. The observation of the indirect feeding of the 2321 keV state in Mg32 removes some restrictions previously placed on the spin assignment for this state. No evidence of a state at 2117 keV in Mg32 is found. Previously unobserved weak transitions up to 5.4 MeV were recorded but could not be placed in the decay scheme of Na32.

  16. Corpo-escrita na esquizofrenia

    OpenAIRE

    Bialer, Marina

    2014-01-01

    Este artigo aborda a importância do trabalho de escrita na esquizofrenia. Toma-se como ponto de partida a formulação lacaniana sobre o esquizofrênico como aquele que não tem as funções dos órgãos do seu corpo dadas pelos discursos estabelecidos. A hipótese de que o trabalho sobre a letra pode permitir o tratamento do gozo debordante na esquizofrenia é analisada pelo estudo da obra do escritor esquizofrênico Robert Walser, a qual evidencia a viabilidade da construção de um corpo pela escrita n...

  17. Capacitação na atenção à saúde do adolescente: experiência de ensino

    Directory of Open Access Journals (Sweden)

    Maria Sylvia de Souza Vitalle

    Full Text Available Trabalho realizado para aferir a instrumentalização recebida por pediatras em curso de Capacitação em Atenção à Saúde Integral do Adolescente. O curso foi realizado no Setor de Medicina do Adolescente da Unifesp, com 10% dos pediatras que atuam na rede municipal de saúde da cidade de São Paulo, com atividades teóricas, teórico-práticas, visitas técnicas, supervisão de intervenções/casos e atualizações nas temáticas prioritárias desta faixa etária. Foram realizados pré e pós-testes com questões de múltipla escolha, um questionário aberto. Dos 120 pediatras inscritos, 85 completaram o curso, 73 (85,8% eram do sexo feminino, a mediana do tempo de atuação em pediatria foi de 18 anos. Se perceberam mais capazes de melhorar a qualidade no atendimento, trabalhar em grupos/equipe multiprofissional, desenvolver ações educativas, diagnosticar melhor doenças e situações de risco, fazer prevenção de doenças, discutir casos e estratégias com outros profissionais, multiplicar conhecimento. Os resultados obtidos sugerem que o modelo de capacitação desenvolvido é adequado para instrumentalizar o profissional já inserido no mercado de trabalho, embora, pela característica do conhecimento médico, deva haver um processo permanente de aquisição de novos conhecimentos e refinamento dos já adquiridos.

  18. Meltability in system of K2TaF7-NaF-NaCl-KCl

    International Nuclear Information System (INIS)

    Kartsev, V.E.; Kovalev, F.V.; Korshunov, B.G.

    1975-01-01

    Thermographic and visual-polythermal techniques were used to study the meltability in K 2 TaF 7 -NaF-NaCl-KCl system. The tetrahedron-forming sections NaF-NaCl-K 2 TaF 7 xKCl and NaF-K 2 TaF 7 xKCl-2K 2 TaF 7 xNaCl divide the concentration tetrahedron into three particular tetrahedra: NaF-K 2 TaF 7 xKCl-2K 2 TaF 7 xNaCl-K 2 TaF 7 , NaF-NaCl-K 2 TaF 7 xKCl-2K 2 TaF 7 xaCl, and NaF-NaCl-KCl-K 2 TaF 7 xKCl. Non-variant equilibrium points in all of the particular four-component systems have been determined

  19. NA60 frees the quarks

    CERN Multimedia

    2003-01-01

    Fitted with new state-of-the-art silicon detectors, NA60 is prepared to study the phase transition from confined hadronic matter to a deconfined (free) quark-gluon plasma, a state of matter which probably existed an instant after the Big Bang.

  20. NA61/SHINE ion program

    CERN Document Server

    Mackowiak, Maja

    2010-01-01

    The Super Proton Synchrotron (SPS) at CERN covers one of the most interesting regions of the phase diagram (T - \\mu_{B}) of strongly interacting matter. The study of central Pb+Pb collisions by NA49 indicate that the threshold for deconfinement is reached already at the low SPS energies. Theoretical considerations predict a critical point of strongly interacting matter at energies accessible at the SPS. The NA61/SHINE experiment, a successor of the NA49 project, will study hadron production in p+p, p+A, h+A, and A+A reactions at various energies. The broad physics program includes the investigation of the properties of strongly interacting matter, as well as precision measurements of hadron spectra for the T2K neutrino experiment and for the Pierre Auger Observatory and KASCADE cosmic-ray projects. The main physics goals of the NA61/SHINE ion program are to study the properties of the onset of deconfinement at low SPS energies and to find signatures of the critical point of strongly interacting matter. To ach...

  1. NA62: Hidden Sector Physics

    CERN Document Server

    Cesarotti, Carissa Joyce

    2016-01-01

    Modern experimental physics is often probing for new physics by either finding deviations from predictions on extremely precise measurements, or by looking for a new signal that cannot be explained with existing models. The NA62 experiment at CERN does the former by measuring the ultra-rare decay $K^+ \\rightarrow \\pi^+ \

  2. The system NaVO3-Na2WO4-Na2W2O7

    International Nuclear Information System (INIS)

    Kazanbekov, V.R.; Gasanaliev, A.M.; Kazanbekov, R.G.

    1994-01-01

    Phase diagrams of sodium metavanadate-sodium ditungstate, sodium metavanadate-sodium tungstate systems and surface of primary crystallization of sodium metavabadate-sodium tungstate-sodium ditungstate system were studied. The system sodium metavanadate-sodium ditungstate is eutectic one. Compound NaVO 3 x2Na 2 WO 4 is formed in solid state in sodium metavanadate-sodium tungstate system. Liquidus surface of sodium metavanadate-sodium tungstate-sodium ditungstate is presented by three crystallization fields of initial components. Composition and melting point of ternary eutectics are determined

  3. Europlanet NA2 Science Networking

    Science.gov (United States)

    Harri, Ari-Matti; Szego, Karoly; Genzer, Maria; Schmidt, Walter; Krupp, Norbert; Lammer, Helmut; Kallio, Esa; Haukka, Harri

    2013-04-01

    Europlanet RI / NA2 Science Networking [1] focused on determining the major goals of current and future European planetary science, relating them to the Research Infrastructure that the Europlanet RI project [2] developed, and placing them in a more global context. NA2 also enhanced the ability of European planetary scientists to participate on the global scene with their own agenda-setting projects and ideas. The Networking Activity NA2 included five working groups, aimed at identifying key science issues and producing reference books on major science themes that will bridge the gap between the results of present and past missions and the scientific preparation of the future ones. Within the Europlanet RI project (2009-2012) the NA2 and NA2-WGs organized thematic workshops, an expert exchange program and training groups to improve the scientific impact of this Infrastructure. The principal tasks addressed by NA2 were: • Science activities in support to the optimal use of data from past and present space missions, involving the broad planetary science community beyond the "space club" • Science activities in support to the preparation of future planetary missions: Earth-based preparatory observations, laboratory studies, R&D on advanced instrumentation and exploration technologies for the future, theory and modeling etc. • Develop scientific activities, joint publications, dedicated meetings, tools and services, education activities, engaging the public and industries • Update science themes and addressing the two main scientific objectives • Prepare and support workshops of the International Space Science Institute (ISSI) in Bern and • Support Trans National Activities (TNAs), Joined Research Activities (JRAs) and the Integrated and Distributed Information Service (IDIS) of the Europlanet project These tasks were achieved by WG workshops organized by the NA2 working groups, by ISSI workshops and by an Expert Exchange Program. There were 17 official WG

  4. Pozitivni in negativni vplivi risank na otroke

    OpenAIRE

    Povše, Nika

    2017-01-01

    V tej diplomski nalogi smo raziskovali pozitivne in negativne vplive risank na otroke. Začeli smo z zgodovino televizije, tako svetovno zgodovino kot zgodovino televizije na Slovenskem. Na isti način smo pregledali tudi zgodovino risank. Raziskovali smo otrokov razvoj, predvsem tiste vidike, ki so izpostavljeni vplivom risank, kot so morala, jezik, domišljija in učenje. Sledilo je raziskovanje negativnih in pozitivnih vplivov, ki jih imajo risanke na otroke, kar je tudi naš glavni problem te ...

  5. Na+-stimulated ATPase of alkaliphilic halotolerant cyanobacterium Aphanothece halophytica translocates Na+ into proteoliposomes via Na+ uniport mechanism

    Directory of Open Access Journals (Sweden)

    Soontharapirakkul Kanteera

    2010-08-01

    Full Text Available Abstract Background When cells are exposed to high salinity conditions, they develop a mechanism to extrude excess Na+ from cells to maintain the cytoplasmic Na+ concentration. Until now, the ATPase involved in Na+ transport in cyanobacteria has not been characterized. Here, the characterization of ATPase and its role in Na+ transport of alkaliphilic halotolerant Aphanothece halophytica were investigated to understand the survival mechanism of A. halophytica under high salinity conditions. Results The purified enzyme catalyzed the hydrolysis of ATP in the presence of Na+ but not K+, Li+ and Ca2+. The apparent Km values for Na+ and ATP were 2.0 and 1.2 mM, respectively. The enzyme is likely the F1F0-ATPase based on the usual subunit pattern and the protection against N,N'-dicyclohexylcarbodiimide inhibition of ATPase activity by Na+ in a pH-dependent manner. Proteoliposomes reconstituted with the purified enzyme could take up Na+ upon the addition of ATP. The apparent Km values for this uptake were 3.3 and 0.5 mM for Na+ and ATP, respectively. The mechanism of Na+ transport mediated by Na+-stimulated ATPase in A. halophytica was revealed. Using acridine orange as a probe, alkalization of the lumen of proteoliposomes reconstituted with Na+-stimulated ATPase was observed upon the addition of ATP with Na+ but not with K+, Li+ and Ca2+. The Na+- and ATP-dependent alkalization of the proteoliposome lumen was stimulated by carbonyl cyanide m - chlorophenylhydrazone (CCCP but was inhibited by a permeant anion nitrate. The proteoliposomes showed both ATPase activity and ATP-dependent Na+ uptake activity. The uptake of Na+ was enhanced by CCCP and nitrate. On the other hand, both CCCP and nitrate were shown to dissipate the preformed electric potential generated by Na+-stimulated ATPase of the proteoliposomes. Conclusion The data demonstrate that Na+-stimulated ATPase from A. halophytica, a likely member of F-type ATPase, functions as an electrogenic Na

  6. Photodesorption of Na atoms from rough Na surfaces

    DEFF Research Database (Denmark)

    Balzer, Frank; Gerlach, R.; Manson, J.R.

    1997-01-01

    We investigate the desorption of Na atoms from large Na clusters deposited on dielectric surfaces. High-resolution translational energy distributions of the desorbing atoms are determined by three independent methods, two-photon laser-induced fluorescence, as well as single-photon and resonance......-enhanced two-photon ionization techniques. Upon variation of surface temperature and for different substrates (mica vs lithium fluoride) clear non-Maxwellian time-of-flight distributions are observed with a cos θ angular dependence and most probable kinetic energies below that expected of atoms desorbing from...... atoms are scattered by surface vibrations. Recent experiments providing time constants for the decay of the optical excitations in the clusters support this model. The excellent agreement between experiment and theory indicates the importance of both absorption of the laser photons via direct excitation...

  7. Impacto de um projeto de extensão universitária na formação profissional de egressos de uma universidade pública

    Directory of Open Access Journals (Sweden)

    Lúcia de Fátima Almeida de Deus Moura

    Full Text Available INTRODUÇÃO: Dentre as competências necessárias à formação profissional em Odontologia no Brasil, está aquela destinada à atuação nos serviços de saúde. Nesse processo de formação, a participação em programas de extensão universitária amplia as possibilidades de aprendizado por permitir a vivência entre os ambientes acadêmico e comunitário. OBJETIVO: Determinar o impacto que as informações e ações desenvolvidas em um programa de extensão universitária exerceram na formação profissional de egressos de uma universidade pública. MATERIAL E MÉTODO: Foi realizado um estudo observacional transversal descritivo. A população do estudo foi composta por 268 cirurgiões-dentistas, que participaram do projeto de extensão universitária do curso de Odontologia da Universidade Federal do Piauí - Programa Preventivo para Gestantes e Bebês, no período de 1997 a 2011. Foi utilizado questionário enviado por e-mail como instrumento de coleta de dados, incluindo perguntas relativas à importância que o programa exerceu na qualificação profissional dos ex-estagiários. RESULTADO: O percentual de resposta foi de 52,6%, ou seja, 141 cirurgiões-dentistas responderam ao questionário. Os resultados apontaram que 98,6% dos sujeitos classificaram o Programa Preventivo para Gestantes e Bebês como ótimo; 91,5% declararam aplicar os conhecimentos adquiridos no projeto em sua rotina profissional; 28,4% implantaram programas semelhantes; 85,8% atendem gestantes em suas rotinas de trabalho e, destes, 19,8% relataram dificuldade nos atendimentos; 69,5% atendem bebês em suas rotinas de trabalho e, destes, 63,3% se sentem capacitados para executar procedimentos clínicos. CONCLUSÃO: As informações e ações desenvolvidas no Programa Preventivo para Gestantes e Bebês apresentaram impacto positivo na qualificação profissional de egressos, contribuindo para que os mesmos atuem com segurança nos atendimentos de gestantes e bebês.

  8. Vpliv konfucija na sodobno izobraževanje na Kitajskem

    Directory of Open Access Journals (Sweden)

    Katja Skitek

    2009-12-01

    Full Text Available Izobraževanje na Kitajskem je bilo vedno trdno povezano s Konfucijem in konfucianizmom, kar pa ni čudno, saj je bil Konfucij prvi, ki je poudarjal moč z nanja in izobraževanja. LR Kitajska je v zadnjih petdesetih letih počasi in postopoma začela uveljavljati določene spremembe v vzgojno-izobraževalni sistem. Kakšne so te spremembe in koliko nanje še vedno vpliva konfucianizem, bo osrednja tema pričujočega članka. Konfucianizem danes na Kitajskem ni preveč popularen, izobraženci pa so se razporedili v dve skupini: eni trdijo, da je njegov vpliv še vedno velik, drugi pa zatrjujejo, da nima več nobenega vpliva na sodobno življenje. Katera stran ima prav? Konfucij je v prvi vrsti poudarjal pomembnost moralnih vrednot vsakega človeka in prav moralne vrednote, za katere se je zavzemal, so še danes trdno zasidrane v kitajski kulturi. Ali je torej sploh mogoče popolnoma izriniti Konfucija iz sodobnega izobraževanja?

  9. Novel aspects of Na+,K+-ATPase

    OpenAIRE

    Aizman, Oleg

    2002-01-01

    Na,K-ATPase, an integral membrane protein expressed in each eukaryotic cell, serves as the major determinant of intracellular ion composition. In the current study we investigated novel aspects of Na,K-ATPase function and regulation. It is well established that Na,K-ATPase activity is regulated by reversible phosphorylation. New findings in this study are: 1) the level of intracellular Ca 2. concentration determines the functional effects of PKA and PKC-mediated Na,K-ATP...

  10. NA64 Status Report 2018

    CERN Document Server

    Gninenko, Sergei

    2018-01-01

    The experiment NA64 is aimed at a search for a sub-GeV vector mediator (called dark photon A′) of Dark Matter production at the CERN SPS. . The main goal in 2017 was to probe a region of the A′ parameter space of the thermal dark matter model. Ongoing activities on the detector and data analysis are reviewed. The status and results from the NA64 runs in 2016 and 2017 are reported. First results on the search for the X->e+e− decay of a 17 MeV X boson, which could explain the recently observed excess of e+e-pairs from the excited 8Be nucleus transitions, and A'-> e+e- decays are also presented. Ongoing analysis on the decays of axion-like particles and plans for further searches beyond LS2 are also discussed.

  11. Makosa Yanayofanywa na Wanafunzi Wanaojifunza Kiswahili kama ...

    African Journals Online (AJOL)

    Makala haya, yanashughulika na makosa ambayo hufanywa na wanafunzi wanaojifunza Kiswahili kama lugha ya pili katika shule za sekondari nchini Uganda. Mtafiti ameyaainisha makosa mbalimbali na kuyaeleza kiusahihi. Makala yanaeleza namna ambavyo makosa hayo hutokea. Yaani, kama ni makosa ...

  12. Pseudo-ternary phase diagram in the Na2O-Na2O2-NaOH system

    International Nuclear Information System (INIS)

    Saito, Jun-ichi; Tendo, Masayuki; Aoto, Kazumi

    1997-10-01

    Generally, the phase diagrams are always used to understand the present state of compounds at certain temperature. In order to understand the corrosion behavior of structural material for FBR by main sodium compounds (Na 2 O, Na 2 O 2 and NaOH), it is very important to comprehend the phase diagrams of their compounds. However, only Na 2 O-NaOH pseudo-binary phase diagram had been investigated previously in this system. There is no study of other pseudo-binary or ternary phase diagrams in the Na 2 O-Na 2 O 2 -NaOH system. In this study, in order to clarify the present states of their compounds at certain temperatures, the pseudo-binary and ternary phase diagrams in the Na 2 O-Na 2 O 2 -NaOH system were prepared. A series of thermal analyses with binary and ternary component system has been carried out using the differential scanning calorimetry (DSC). The liquidus temperature and ternary eutectic temperatures were confirmed by these measurements. The beneficial indications for constructing phase diagrams were obtained from these experiments. On the basis of these results, the interaction parameters between compounds which were utilized for the Thermo-Calc calculation were optimized. Thermo-Calc is one of thermodynamic calculation software. Consequently the accurate pseudo-binary and ternary phase diagrams were indicated using the optimized parameters. (author)

  13. Na+,K+-ATPase Na+ affinity in rat skeletal muscle fiber types

    DEFF Research Database (Denmark)

    Kristensen, Michael; Juel, Carsten

    2010-01-01

    Previous studies in expression systems have found different ion activation of the Na(+)/K(+)-ATPase isozymes, which suggest that different muscles have different ion affinities. The rate of ATP hydrolysis was used to quantify Na(+),K(+)-ATPase activity, and the Na(+) affinity of Na(+),K(+)-ATPase...

  14. Homocisteína Homocysteine

    Directory of Open Access Journals (Sweden)

    Lindalva Batista Neves

    2004-10-01

    Full Text Available A homocisteína, formada a partir da metionina hepática, é metabolizada nas vias de desmetilação e de transulfuração, sendo que seus valores plasmáticos e urinários refletem a síntese celular. Sua determinação, realizada em jejum e após sobrecarga de metionina, caracteriza as diferenças dessas vias metabólicas, principalmente quando de natureza genética. A hiper-homocisteinemia tem sido associada a maior risco de eventos aterotrombóticos, e a literatura sugere associação causal, independente de outros fatores de risco para doença arterial. Diminuição da homocisteína plasmática para valores normais é seguida de redução significante na incidência de doença aterotrombótica. A relação entre homocisteína e o fígado vem adquirindo importância nos dias atuais, uma vez que alterações das lipoproteínas e da depuração de metionina são comuns em pacientes com doença hepática crônica (hepatocelular e canalicular. O tratamento da hiper-homocisteinemia fundamenta-se na suplementação alimentar e medicamentosa de ácido fólico e vitaminas B6 e B12.Homocysteine, formed from hepatic methionine, is metabolized through the pathways of demethylation and transsulfuration. Its plasmatic and urinary values reflect the cell synthesis. Its determination after fasting and increased infusion of methionine shows the differences of these two metabolic pathways, mainly when it is related to genetic diseases. Hyperhomocysteinemia has been associated with a higher risk of vascular thrombotic events. Several authors suggest a causal relationship between these events independently of other risk factors for vascular diseases. Decrease in plasmatic homocysteine to normal levels is followed by a significant reduction on the incidence of vascular thrombotic events. The correlation between the liver and homocysteine is becoming more important because of the recent findings that alterations of lipoproteins and methionine clearance are

  15. Myocardial Na,K-ATPase: Clinical aspects

    OpenAIRE

    Kjeldsen, Keld

    2003-01-01

    The specific binding of digitalis glycosides to Na,K-ATPase is used as a tool for Na,K-ATPase quantification with high accuracy and precision. In myocardial biopsies from patients with heart failure, total Na,K-ATPase concentration is decreased by around 40%; a correlation exists between a decrease in heart function and a decrease in Na,K-ATPase concentration. During digitalization, around 30% of remaining pumps are occupied by digoxin. Myocardial Na,K-ATPase is also influenced by other drugs...

  16. Crowdsourcing: impactos na performance na venda de produtos

    OpenAIRE

    Alves, Milton Ruiz Rodrigues

    2015-01-01

    Vivemos num momento em que as expectativas de pensadores como Lévy (1998), se concretizaram. O consumidor mudou, passou a exigir um diálogo entre a empresa e a sociedade. Esse novo cenário cobrou da tecnologia formas de aperfeiçoar e agilizar este processo de comunicação, plataformas baseadas na internet que propiciem e incentivam a troca de informações. Nesta esfera surgiu o crowdsourcing, com a disponibilização do capital intelectual das massas, que acabou por mudar a form...

  17. Silicene for Na-ion battery applications

    KAUST Repository

    Zhu, Jiajie

    2016-08-19

    Na-ion batteries are promising candidates to replace Li-ion batteries in large scale applications because of the advantages in natural abundance and cost of Na. Silicene has potential as the anode in Li-ion batteries but so far has not received attention with respect to Na-ion batteries. In this context, freestanding silicene, a graphene-silicene-graphene heterostructure, and a graphene-silicene superlattice are investigated for possible application in Na-ion batteries, using first-principles calculations. The calculated Na capacities of 954mAh/g for freestanding silicene and 730mAh/g for the graphenesilicene superlattice (10% biaxial tensile strain) are highly competitive and potentials of >0.3 V against the Na/Na potential exceed the corresponding value of graphite. In addition, the diffusion barriers are predicted to be <0.3 eV.

  18. Reconstrução da parede torácica nos defeitos adquiridos

    Directory of Open Access Journals (Sweden)

    Marcus Vinicius H. de Carvalho

    Full Text Available Acquired chest wall defects present a challenging problem for thoracic surgeons. Many of such defects can be repaired with the use of local and regional musculocutaneous flaps, but larger defects compromising skeletal structure require increasingly sophisticated reconstructive techniques. The following discussion will review the options for repair acquired chest wall defects based in literature. The authors searched the Pubmed (www.pubmed.com and found citations from January 1996 to February 2008. By reading the titles and the abstracts most of the citations were discharged because they focused in congenital chest wall defects or were cases report. However, many papers were found describing the outcome of large series of patients with acquired chest wall deformities. A review of recent literature shows that the repair of chest wall defects with soft tissues, if possible, remains the treatment of choice. Large chest wall defects require skeletal reconstruction to prevent paradoxical respiration. The selection of the most appropriate flap is primary dictated by the location and the size of the defect. It is important to transfer tissue with good vitality, so understanding the vascular supply is imperative. Autogenous grafts have been used in the past for skeletal reconstruction but a combination of synthetic materials with musculocutaneous flaps has been used lately. Based in the literature, the use of prosthetic material in chest wall reconstruction does not significantly increases the risk of wound infection.

  19. Factores determinantes del nivel de compromiso medioambiental voluntario adquirido por los hoteles cotizados europeos

    OpenAIRE

    Patricia Milanés Montero; Esteban Pérez Calderón; Francisco Javier Ortega Rossell

    2012-01-01

    Ante las importantes presiones que la actividad hotelera ejerce sobre el medioambiente, la ausencia de regulación de las actuaciones responsables y la escasez de investigaciones al respecto aparece la imperiosa necesidad de aportar luz en este sentido. Por ello, en este trabajo se analiza el compromiso medioambiental corporativo de los hoteles cotizados europeos; se utiliza como metodología el análisis de contenidos y se detectan los factores determinantes de las actuaciones responsables con ...

  20. Factores determinantes del nivel de compromiso medioambiental voluntario adquirido por los hoteles cotizados europeos

    Directory of Open Access Journals (Sweden)

    Patricia Milanés Montero

    2012-01-01

    Full Text Available Ante las importantes presiones que la actividad hotelera ejerce sobre el medioambiente, la ausencia de regulación de las actuaciones responsables y la escasez de investigaciones al respecto aparece la imperiosa necesidad de aportar luz en este sentido. Por ello, en este trabajo se analiza el compromiso medioambiental corporativo de los hoteles cotizados europeos; se utiliza como metodología el análisis de contenidos y se detectan los factores determinantes de las actuaciones responsables con el medioambiente con el propósito de contribuir a la construcción de un marco de referencia objetivo de medida de los avances en sostenibilidad de la actividad turística. Además, se contribuye al "argumento comercial" analizando la relación existente entre la rentabilidad empresarial y el desempeño medioambiental. Los resultados muestran que la mayoría de los hoteles analizados carece de política de protección medioambiental; asimismo, el tamaño, la normativa contable adoptada y la pertenencia a grupos son factores determinantes de la adopción de una postura más o menos responsable. Por otro lado, la rentabilidad empresarial resulta ser una de las ventajas de la integración de las cuestiones medioambientales en la estrategia corporativa de las empresas.

  1. Hali ya taaluma ya ukalimani Tanzania: jana, leo na kesho ...

    African Journals Online (AJOL)

    Umuhimu wa ukalimani katika mawasiliano umeongezeka kutokana na utandawazi. Utandawazi umerahisisha kukutanika na kuwasiliana kwa watu wazungumzao lugha tofauti kupitia wakalimani. Kutokana na ongezeko hilo la umuhimu wa ukalimani, kumekuwa na jitihada mbalimbali katika nchi mbalimbali kuhakikisha ...

  2. New results from NA49

    CERN Document Server

    Afanasiev, S V; Bächler, J; Barna, D; Barnby, L S; Bartke, Jerzy; Barton, R A; Behler, M; Betev, L; Bialkowska, H; Billmeier, A; Blume, C; Blyth, C O; Boimska, B; Botje, M; Bracinik, J; Brady, F P; Bramm, R; Brun, R; Buncic, P; Carr, L; Cebra, D; Cerny, V; Cooper, G E; Cramer, J G; Csató, P; Dinkelaker, P; Eckardt, V; Eckhardt, F; Ferenc, D; Filip, P; Fischer, H G; Foder, Z; Foka, P Y; Freund, P; Friese, V; Gál, J; Ganz, R E; Gazdzicki, M; Georgopoulos, G; Gladysz-Dziadus, E; Harris, J W; Hegyi, S; Höhne, C; Igo, G; Jacobs, P; Jones, P G; Kadija, K; Kolesnikov, V I; Kollegger, T; Kowalski, M; Kraus, I; Kreps, M; Lasiuk, B; Van Leeuwen, M; Lévai, Peter; Malakhov, A I; Margetis, S; Markert, C; Mayes, B W; Melkumov, G L; Mischke, A; Molnár, J; Nelson, J M; Odyniec, Grazyna Janina; Oldenburg, M; Pálla, G; Panagiotou, A D; Perl, K; Petridis, A; Pikna, M; Pinsky, L; Poskanzer, A M; Prindle, D J; Pühlhofer, F; Putschke, J; Reid, J G; Renfordt, A; Retyk, W; Ritter, H G; Röhrich, D; Roland, C; Roland, G; Rybicki, A; Sammer, T; Sann, H; Schäfer, E; Schmitz, N; Seyboth, P; Siklér, F; Sitár, B; Skrzypczak, E; Snellings, R; Squier, G T A; Stock, Reinhard; Ströbele, H; Susa, T; Szentpétery, I; Sziklai, J; Toy, M; Trainor, T A; Trentalange, S; Ullrich, T S; Varga, D; Vassiliou, Maria; Veres, G I; Vesztergombi, G; Voloshin, S A; Vranic, D; Wang, F; Weerasundara, D D; Wenig, S; Wetzler, A; Whitten, C; Xu, N; Yates, T A; Koo, I K; Zaranek, J; Zimányi, J

    2002-01-01

    Recent results of the NA49 experiment are presented. These cover first results on pion and kaon production, HBT, and charge fluctuations from Pb+Pb reactions at 40 AGeV and their comparison to 158 AGeV beam energy. Furthermore a study on baryon number transfer in p+p, centrality selected p+Pb and Pb+Pb collisions at 158 AGeV and new results on the system size dependence of kaon yields, including C+C and Si+Si data, are presented. Additionally, a first result on Lambda Lambda correlations is shown. (11 refs).

  3. Loucura imperial na Roma antiga

    Directory of Open Access Journals (Sweden)

    Aloys Winterling

    2012-06-01

    Full Text Available Este artigo aborda a questão da "loucura imperial" na Roma antiga, indagando-se sobre o que seria peculiar a ações de imperadores, como Calígula, Nero e Domiciano, que conduziu a conflitos com a aristocracia. Argumenta-se que apenas uma análise das estruturas e sistemas históricos do Alto Império possibilita explicar certos padrões de comportamento imperial, usualmente classificados como loucura pela historiografia dos séculos XIX e XX.

  4. The effect of Na vapor on the Na content of chondrules

    Science.gov (United States)

    Lewis, R. Dean; Lofgren, Gary E.; Franzen, Hugo F.; Windom, Kenneth E.

    1993-01-01

    Chondrules contain higher concentrations of volatiles (Na) than expected for melt droplets in the solar nebula. Recent studies have proposed that chondrules may have formed under non-canonical nebular conditions such as in particle/gas-rich clumps. Such chondrule formation areas may have contained significant Na vapor. To test the hypothesis of whether a Na-rich vapor would minimize Na volatilization reaction rates in a chondrule analog and maintain the Na value of the melt, experiments were designed where a Na-rich vapor could be maintained around the sample. A starting material with a melting point lower that typical chondrules was required to keep the logistics of working with Na volatilization from NaCl within the realm of feasibility. The Knippa basalt, a MgO-rich alkali olivine basalt with a melting temperature of 1325 +/- 5 C and a Na2O content of 3.05 wt%, was used as the chondrule analog. Experiments were conducted in a 1 atm, gas-mixing furnace with the fO2 controlled by a CO/CO2 gas mixture and fixed at the I-W buffer curve. To determine the extent of Na loss from the sample, initial experiments were conducted at high temperatures (1300 C - 1350 C) for duration of up to 72 h without a Na-rich vapor present. Almost all (up to 98%) Na was volatilized in runs of 72 h. Subsequent trials were conducted at 1330 C for 16 h in the presence of a Na-rich vapor, supplied by a NaCl-filled crucible placed in the bottom of the furnace. Succeeding Knudsen cell weight-loss mass-spectrometry analysis of NaCl determined the P(sub Na) for these experimental conditions to be in the 10(exp -6) atm range. This value is considered high for nebula conditions but is still plausible for non-canonical environments. In these trials the Na2O content of the glass was maintained or in some cases increased; Na2O values ranged from 2.62% wt to 4.37% wt. The Na content of chondrules may be controlled by the Na vapor pressure in the chondrule formation region. Most heating events capable

  5. O ATLETISMO NA PERSPECTIVA EDUCACIONAL

    Directory of Open Access Journals (Sweden)

    Leandro Araujo de Sousa

    2017-06-01

    Full Text Available A educação física escolar deve proporcionar experiências aos alunos para o seu desenvolvimento integral. As aulas muitas vezes são reduzidas ao ensino de esportes tradicionais, o que limita o repertório de movimentos dos alunos. Dessa forma o presente estudo de revisão objetiva problematizar o atletismo no ambiente escolar e propor possibilidades pedagógicas para seu ensino. Nesta pesquisa propomos tratar o ensino do atletismo na escola, caracterizando-o pelo seu repertório de movimentos que são naturais ao ser humano, como correr, saltar e lançar, o que possibilita maior praticidade em sua aplicação pedagógica, porém essas possibilidades não são consideradas no ambiente educacional. Diante dos dados encontrados, sugerimos que esse esporte seja abordado de forma multidimensional no ambiente escolar contextualizando-o à visão de algumas correntes teóricas. Nessa perspectiva do esporte educacional, o atletismo pode, assim como deve ser trabalhado nas aulas de educação física como instrumento pedagógico de ensino e auxiliar na formação do aluno de forma global.

  6. Identidades Homossexuais na Territorialidade Tradicionalista

    Directory of Open Access Journals (Sweden)

    Edipo Djavan dos Reis Göergen

    2015-12-01

    Full Text Available Este artigo apresenta o debate teórico que sustenta a pesquisa de mestrado desenvolvida pelo autor. Tendo por base suas vivências em contextos de tradicionalismo gaúcho, o autor deste trabalho tem percebido a grande quantidade de homossexuais, ou indivíduos que se auto-denominam não-heterossexuais, integrando as atividades artísticas do Movimento Tradicionalista Gaúcho, ou a territorialidade tradicionalista. Interessado em investigar tal fenômeno, o autor tem desenvolvido o projeto de pesquisa “Os Espaços Paradoxais de Relações Homoeróticas na Territorialidade Tradicionalista”, sob orientação do prof. Dr. Benhur Pinós da Costa, no Programa de Pós-Graduação em Geografia (UFSM. Para que essa pesquisa seja realizada, levam-se em conta as relações de gênero e de sexualidade que estão envolvidas no tema. Dessa forma, por ainda se tratarem de temáticas tidas como insignificantes na sociedade em geral e marginalizadas no campo científico, para que o presente trabalho fosse empreendido, buscou-se amparo teórico nas geografias feministas e queer, segmentos contemporâneos da ciência geográfica.

  7. Relationship between intracellular Na+ concentration and reduced Na+ affinity in Na+,K+-ATPase mutants causing neurological disease

    DEFF Research Database (Denmark)

    Toustrup-Jensen, Mads Schak; Einholm, Anja P.; Schack, Vivien

    The neurological disorders familial hemiplegic migraine type 2 (FHM2), alternating hemiplegia of childhood (AHC), and rapid-onset dystonia parkinsonism (RDP) are caused by mutations of Na+,K+-ATPase α2 and α3 isoforms, expressed in glial and neuronal cells, respectively. Although these disorders......, addressing the question to what extent they cause a change of the intracellular Na+ and K+ concentrations ([Na+]i and [K+]i) in COS cells. C-terminal extension mutants generally showed dramatically reduced Na+ affinity without disturbance of K+ binding, as did other RDP mutants. No phosphorylation from ATP...

  8. Fotografia na Imprensa: conflitos na câmara escura

    Directory of Open Access Journals (Sweden)

    José Lúcio da Silva Menezes

    2014-07-01

    Full Text Available Este artigo recupera o teor ideológico do discurso que a Revista Veja elaborou sobre a classe trabalhadora que emergiu no cenário brasileiro, no final da década de 1970. O destaque dado aos trabalhadores como temática central resgatada, deve-se aos movimentos grevistas por eles encetados, após anos de ocultamento de sua resistência sob a repressão da ditadura civil-militar (1964-1985. Com a rebeldia operária, as matérias a respeito deste grupo, na Revista,foram se tornando mais constantes e visíveis, pois já não era mais possível, para a Revista Veja, ignorar a existência da classe operária que, com a força insurgente das greves, ocupava as ruas do Brasil.

  9. Uso da papaína na úlcera plantar

    OpenAIRE

    Otuka, Elizabet Shizue; Pedrazzani, Elisete Silva; Pioto, Mariangela Pedroso

    1996-01-01

    Este trabalho teve por objetivo contribuir para a diminuição da incapacidade em hanseníase e as contínuas recidivas de úceras plantares, através da utilização de um método de tratamento com o uso da papaína e ações de educação em saúde. Foi realizado em um Centro de Saúde com pacientes que apresentavam úcera plantar e que concordaram em participar do tratamento proposto. Analisando e comparando os dados obtidos antes e após o tratamento, concluímos que durante o tratamento foi observada uma m...

  10. Na and K dependence of the Na/K pump in cystic fibrosis fibroblasts.

    OpenAIRE

    Reznik, V M; Schneider, J A; Mendoza, S A

    1981-01-01

    The Na and K dependence of the Na/K pump was measured in skin fibroblasts from patients with cystic fibrosis and age/sex-matched controls. Under basal conditions, there was no difference between control and cystic fibrosis cells in protein per cell, intracellular Na and K content, or Na/K pump activity (measured as ouabain-sensitive 86Rb uptake). There was no difference in the Na dependence of the Na/K pump between cystic fibrosis cells and control cells. In cells from patients with cystic fi...

  11. Vpliv toplotnih mostov na porabo energije za ogrevanje na primeru osnovne šole

    OpenAIRE

    Megušar, Primož

    2015-01-01

    Na primeru Osnovne šole Dobrova sem preveril, kakšen vpliv imajo dejanski toplotni mostovi na porabo energije za ogrevanje. Iz načrtov stavbe sem evidentiral vse toplotne mostove, kateri vplivajo na porabo energije. Tem toplotnim mostovom sem nato v standardu SIST EN ISO 14683 poiskal ustrezne približke. Nato sem s programom TOST izvedel tri simulacije. V prvem primeru toplotnih mostov nisem upošteval. V drugem primeru sem toplotne mostove upošteval na poenostavljen način, v zadnjem primeru p...

  12. Low-spin states of 23Na

    International Nuclear Information System (INIS)

    Bakkum, E.L.

    1987-01-01

    A study of 23 Na via the 22 Ne(p,γ) 23 Na and 23 Na(γ,γ) 23 Na reactions is presented. Only a limited number of resonances has been studied, selected on the basis of strong excitation of the lowest levels of which the spin was unknown. As a result the spins are now known of all levels of 23 Na with excitation energies up to 7 MeV, except for a few high-spin states which are too weakly excited in the decay of the known 22 Ne(p,γ) resonances. The mean lifetimes of the 23 Na levels at 4.43 and 7.89 MeV were found to be 350±70 and 220±17 attoseconds (1 attosecond = 10 -18 seconds) respectively. 97 refs.; 22 figs.; 12 tabs

  13. PRIMERJAVA GEODETSKIH METOD NA ZAHTEVNEM GRADBENEM OBJEKTU

    OpenAIRE

    Reberčnik, Matic

    2017-01-01

    V projektni nalogi smo v uvodnih poglavjih predstavili različne načine izvajanja geodetskih meritev, ki jih v gradbeništvu uporabljamo pri analizi pomikov in deformacij gradbenih konstrukcij ter terena, na katerem so le-te postavljene. V nadaljevanju opisujemo terestične in GNSS (globalni navigacijski satelitski sistem) metode, ki smo jih uporabljali pri izvajanju meritev na izbranem premostitvenem objektu avtocestnega odseka v Sloveniji (zaradi varovanja podatkov ga imenujemo Objekt 1). Pod...

  14. Pioneering instrumentation aspects of NA60

    International Nuclear Information System (INIS)

    David, Andre

    2004-01-01

    NA60 is taking data with proton and heavy-ion beams at the CERN SPS. Although building up on previous experiments, the dimuon physics programme of NA60 places very demanding requirements on its new detectors, in terms of radiation tolerance, granularity and read-out electronics speed. We start by comparing dimuon detection strategies in NA60 with those of previous experiments. We then describe the new detectors used in NA60, placing particular emphasis on their technological pioneering aspects as well as on their contributions to the overall physics performance of the experiment

  15. Fabrication of implanted $^{22}$Na targets

    CERN Multimedia

    2002-01-01

    A knowledge of the $^{22}$Na(p,$\\gamma$)$^{23}$ Mg reaction rate is of significant astrophysical interest. In order to complete previous studies of this reaction, radioactive $^{22}$Na targets of high purity are required. We ask for support to fabricate these targets via the implantation technique at ISOLDE GPS (off—line mode) using $^{22}$Na nuclides in an Al matrix produced in Nov. 1990 at the PSI (Zürich). The $^{22}$Na nuclides are released and ionized in a surface ionisation source, mass-analyzed at ISOLDE GPS, and implanted in a Ni-Ta backing and a C—foil in a special implantation setup.

  16. OGLAŠEVANJE NA FACEBOOKU V SLOVENIJI

    OpenAIRE

    Dobnik, Monja

    2013-01-01

    Danes so zahvaljujoč napredni mobilni tehnologiji družbena omrežja z nami na vsakem koraku. Facebook (FB) se po priljubljenosti uvršča v sam vrh družbenih omrežij in glede na to, da ga uporablja že več kot milijarda zemljanov, ponuja tudi odlične trg za oglaševanje. To so ugotovili tudi slovenski podjetniki. V diplomski nalogi je predstavljeno, kako na FB oglašujejo nekatera slovenska podjetja, s pomočjo spletnega vprašalnika pa je ugotovljeno tudi, kaj o oglasih na FB menijo njegovi uporabni...

  17. Entrada vocabular na linguagem virtual

    OpenAIRE

    Macedo, Valdete Aparecida Xavier de [UNESP

    2002-01-01

    O objetivo deste trabalho foi o de fazer um estudo sobre a projeção do inglês, língua universal, sobre a portuguesa, considerando-se os empréstimos lexicais, porta de entrada para a configuração e enriquecimento vocabular da língua de chegada. Estes vocábulos são indicativos ao vocabulário da língua de especialidade, divulgados nos programas da Internet. Fizemos uma pequena reflexão sobre o fenômeno da linguagem virtual, que vem se cristalizando em discurso interativo de povos e nações coloca...

  18. Zbigniew Herbert, Znaki na papierze

    Directory of Open Access Journals (Sweden)

    Thibault Deleixhe

    2008-10-01

    Full Text Available Dans une interview, Zbigniew Herbert confiait : « Mon travail préparatoire à un livre, ce sont avant tout des dessins. Je ne fais pas de photos, cela simplifierait mon contact avec l’objet. » Il n’en fallait pas moins pour donner aux éditions Bosz l’envie d’un projet : réunir ces précieuses esquisses de travail et les confronter aux textes qui en sont nés. Le résultat s’intitule Znaki na papierze (Signes sur papier et appartient aux objets que l’on est fier de posséder dans sa bibliothèque. ...

  19. O consumo na vida digital

    Directory of Open Access Journals (Sweden)

    Iuri Yudi Furukita Baptista

    2016-02-01

    Full Text Available O modelo de consumo não possui as mesmas características sempre: suas relações, motivações, formatos, espaços, interesses e atividades são construções sociais que se modificam atreladas ao cenário econômico, político e tecnológico. O presente trabalho repassa o surgimento da sociedade do consumidor para então conjecturar sobre as propriedades distintivas do consumo na vida digital. O que se defende ao final é que o consumidor já não se restringe ao papel de consumir.

  20. Odpowiedź na pytanie

    Directory of Open Access Journals (Sweden)

    Michel Foucault

    2016-12-01

    Full Text Available Prezentowany artykuł Michela Foucaulta został opublikowany w 1963 roku. Foucault rozwija w nim koncepcję archeologii wiedzy – metody analizy historycznych dyskursów, którą zaprezentuje w sześć lat później w książce o tym właśnie tytule. Artykuł powstał na kanwie pytania wybranego przez autora spośród zadanych mu przez redakcję „Esprit”, które dotyczyło możliwości pojęciowego opracowania przymusu systemu dyskursywnego przy jednoczesnym zaakcentowaniu nieciągłości w jego obrębie a tym samym możliwości twórczego działania w historii ducha. A także, czy tak sformułowana aporia zakładałaby z konieczności zgodę na przymus systemu lub afirmację siły zdolnej do przekształcenia go za pomocą zewnętrznej przemocy? Tekst jest wprawką do sformułowania dojrzałej teorii dyskursu, rodzajem autoanalizy, która pozwala Foucaultowi powiązać własną metodę historyczną z „progresywistyczną polityką” myśli i rozwiązać w ten sposób dylemat pełnej determinacji i wolnego sprawstwa obecny w rozważaniach wielu strukturalistów.

  1. Na+/Ca2+ exchange and Na+/K+-ATPase in the heart

    Science.gov (United States)

    Shattock, Michael J; Ottolia, Michela; Bers, Donald M; Blaustein, Mordecai P; Boguslavskyi, Andrii; Bossuyt, Julie; Bridge, John H B; Chen-Izu, Ye; Clancy, Colleen E; Edwards, Andrew; Goldhaber, Joshua; Kaplan, Jack; Lingrel, Jerry B; Pavlovic, Davor; Philipson, Kenneth; Sipido, Karin R; Xie, Zi-Jian

    2015-01-01

    This paper is the third in a series of reviews published in this issue resulting from the University of California Davis Cardiovascular Symposium 2014: Systems approach to understanding cardiac excitation–contraction coupling and arrhythmias: Na+ channel and Na+ transport. The goal of the symposium was to bring together experts in the field to discuss points of consensus and controversy on the topic of sodium in the heart. The present review focuses on cardiac Na+/Ca2+ exchange (NCX) and Na+/K+-ATPase (NKA). While the relevance of Ca2+ homeostasis in cardiac function has been extensively investigated, the role of Na+ regulation in shaping heart function is often overlooked. Small changes in the cytoplasmic Na+ content have multiple effects on the heart by influencing intracellular Ca2+ and pH levels thereby modulating heart contractility. Therefore it is essential for heart cells to maintain Na+ homeostasis. Among the proteins that accomplish this task are the Na+/Ca2+ exchanger (NCX) and the Na+/K+ pump (NKA). By transporting three Na+ ions into the cytoplasm in exchange for one Ca2+ moved out, NCX is one of the main Na+ influx mechanisms in cardiomyocytes. Acting in the opposite direction, NKA moves Na+ ions from the cytoplasm to the extracellular space against their gradient by utilizing the energy released from ATP hydrolysis. A fine balance between these two processes controls the net amount of intracellular Na+ and aberrations in either of these two systems can have a large impact on cardiac contractility. Due to the relevant role of these two proteins in Na+ homeostasis, the emphasis of this review is on recent developments regarding the cardiac Na+/Ca2+ exchanger (NCX1) and Na+/K+ pump and the controversies that still persist in the field. PMID:25772291

  2. Efetividade de uma técnica educativa na aquisição de conhecimentos por pais sobre uso racional do flúor = Effectiveness of an educative techinique on knowledge acquisition on ratinal use of fluorine by parents

    Directory of Open Access Journals (Sweden)

    Martins, Carolina de Castro

    2006-01-01

    Full Text Available O objetivo do presente estudo foi testar o conhecimento sobre uso racional de flúor adquirido através de grupo de discussão (GD. Um grupo de 47 pais de crianças pré-escolares constituiu a amostra após a assinatura de um termo de consentimento livre e esclarecido. Este estudo foi aprovado por um Comitê de ética em Pesquisa. Para averiguação do nível de conhecimento inicial sobre o tema proposto, os participantes responderam a um questionário com 14 perguntas abertas e fechadas. Seis meses após esta etapa, foi realizado um GD sobre o uso racional de flúor. O GD proposto abordou a metodologia pedagógica problematizadora e contou com a participação ativa dos pais e de três cirurgiões dentistas. Neste momento foram apresentadas afirmações sobre a utilização do flúor pela população, a partir das quais a discussão era deflagrada. Alguns dias após, os pais responderam novamente o questionário inicial. Os dados foram submetidos aos testes estatístico Qui-quadrado e exato de Fisher através do programa SPSS. Houve diferença estatisticamente significante entre praticamente todas as respostas no primeiro e segundo questionários (p < 0,005, sendo que no segundo, houve um maior número de respostas corretas. A técnica educativa avaliada mostrou-se efetiva na incorporação de novos conhecimentos sobre o uso racional de flúor pelos pais, evidenciando a eficácia da metodologia empregada

  3. Kinetin Reversal of NaCl Effects

    Science.gov (United States)

    Katz, Adriana; Dehan, Klara; Itai, Chanan

    1978-01-01

    Leaf discs of Nicotiana rustica L. were floated on NaCl in the presence of kinetin or abscisic acid. On the 5th day 14CO2 fixation, [3H]leucine incorporation, stomatal conductance, and chlorophyll content were determined. Kinetin either partially or completely reversed the inhibitory effects of NaCl while ABA had no effect. PMID:16660618

  4. Silicene for Na-ion battery applications

    KAUST Repository

    Zhu, Jiajie; Schwingenschlö gl, Udo

    2016-01-01

    Na-ion batteries are promising candidates to replace Li-ion batteries in large scale applications because of the advantages in natural abundance and cost of Na. Silicene has potential as the anode in Li-ion batteries but so far has not received

  5. Negative electrodes for Na-ion batteries.

    Science.gov (United States)

    Dahbi, Mouad; Yabuuchi, Naoaki; Kubota, Kei; Tokiwa, Kazuyasu; Komaba, Shinichi

    2014-08-07

    Research interest in Na-ion batteries has increased rapidly because of the environmental friendliness of sodium compared to lithium. Throughout this Perspective paper, we report and review recent scientific advances in the field of negative electrode materials used for Na-ion batteries. This paper sheds light on negative electrode materials for Na-ion batteries: carbonaceous materials, oxides/phosphates (as sodium insertion materials), sodium alloy/compounds and so on. These electrode materials have different reaction mechanisms for electrochemical sodiation/desodiation processes. Moreover, not only sodiation-active materials but also binders, current collectors, electrolytes and electrode/electrolyte interphase and its stabilization are essential for long cycle life Na-ion batteries. This paper also addresses the prospect of Na-ion batteries as low-cost and long-life batteries with relatively high-energy density as their potential competitive edge over the commercialized Li-ion batteries.

  6. Razvitak naselja na kvarnerskim otocima - primjer Dobrinja

    Directory of Open Access Journals (Sweden)

    Marijan Bradanović

    2012-12-01

    Full Text Available Na dosad slabo poznatom i sa stajališta povijesti umjetnosti još posve neobrađenom primjeru Dobrinja na otoku Krku, raspravlja se o razvitku naselja na kvarnerskim otocima. Uz isticanje štetnosti dosad prevladavajućih uopćavanja, karakteristični položaj i razvitak Dobrinja tumače se u širem, komparativnom kontekstu. Analiziraju se prostiranje i obilježja pojedinih dijelova ovog naselja, a naglasak je na vremenu kasnog srednjeg i ranijeg novog vijeka. Tada je najuži dio povijesnog središta Dobrinja poprimio čvrstu, na tlorisnoj osnovi i danas, usprkos opsežnim pregradnjama i arhitektonskim preinakama, jasno uočljivu, urbanu fizionomiju.

  7. Bullying na Escola: um sofrimento

    Directory of Open Access Journals (Sweden)

    Marlene Silva Sardinha Gurpilhares

    2014-07-01

    Full Text Available O bullying é uma forma de violência presente nas escolas e o termo é utilizado para caracterizar todas as formas de agressões repetitivas psicológicas e físicas, direta ou indiretamente. Esta violência causa sofrimentos, intimidação e medo, sempre numa relação de poder entre pares. Esta pesquisa trata de um estudo do bullying escolar: o que é, como surgiu, como identificá-lo e sua caracterização, conseqüências, causas, o papel da escola, de professores e pais e uma proposta prática que pode ser adotada para sua prevenção e contenção. O objetivo é organizar materiais para leitura dos atores educacionais para uma possível reflexão, através de pesquisas bibliográficas. Esta violência é grave e deveria ser tratada como saúde pública, devido às conseqüências que traz, como queda na aprendizagem, na autoestima e em casos mais graves, até o suicido e outras tragédias. A escola necessita atentar para esse tipo de violência, revendo suas ações em todos os momentos, tendo um olhar integral e diferenciado em relação aos alunos. É fundamental que o bullying não seja tratado como brincadeira de criança e para ser identificado e combatido é necessária uma ação entre a família e todos da escola, que pode ser desenvolvida através de projetos que ajudem a apontar caminhos para a solução do problema. Tais ações devem ser pautadas por constantes debates e reflexões, nas quais o aluno se torne o protagonista. Não existem fórmulas prontas, pois a intervenção deve ser feita através da realidade de cada escola.

  8. Study of the Na-C-O and Na-H-O ternary systems in the sodium rich corner

    International Nuclear Information System (INIS)

    Maupre, J.-P.

    1978-02-01

    The purpose of this study is to provide a contribution to the understanding of the sodium - carbon - oxygen and sodium - hydrogen - oxygen ternary systems in the sodium rich corner. In order to do this the Na-NaH-Na 2 O-NaOH phase diagram was completed and the Na-Na 2 O-Na 2 CO 3 -C phase diagram was outlined. This work is made up of two parts. The first is devoted to a critical literature survey essential to establish correct phase diagrams. The second is an experimental study followed by a discussion collating our finding to the literary data. The basic experimental technique used is differential thermal analysis (DTA) but it has been completed by quenching, X-ray and chemical analysis methods. The proposed phase diagrams imply that Na-NaH-Na 2 O-NaOH and Na-Na 2 O-Na 2 CO 3 -C systems are reciprocal ternary systems. Temperatures of stable pairs reversal are respectively 410 and 690 0 C. The stable pairs are Na-NaOH and Na-Na 2 CO 3 at elevated temperature, Na 2 O-NaH and Na 2 O-C at low temperature [fr

  9. OGLAŠEVANJE NA DRUŽBENIH OMREŽJIH NA PRIMERU FACEBOOKA

    OpenAIRE

    Novak, Martina

    2012-01-01

    V diplomskem delu obravnavamo družbene medije kot novo priložnost za promocijo in oglaševanje podjetij. Spoznali smo družbena omrežja na splošno in nekaj teh, ki jih uporabljamo tudi v Sloveniji na kratko predstavili. Podrobneje smo se osredotočili na družbeno omrežje Facebook, predvsem na samo spletno stran, njen izgled in storitve, ki jih ponuja uporabnikom. V nalogi je podrobneje opisan Facebook kot orodje za uporabo oglaševanja. Spoznali smo brezplačne in plačljive načine promocije in ogl...

  10. A Influência da Escola e da Mídia na Obtenção dos Conhecimentos Astronômicos

    Science.gov (United States)

    da Cunha, W. S.; Voelzke, M. R.; Amaral, L. H.

    2006-08-01

    O universo em que vivemos possui segredos jamais imaginados pelo homem, fruto da pequena proporção que ocupamos diante de um cosmos infinito. A astronomia funciona como um instrumento que sacia a sede humana em desvendar esses segredos, estudando as galáxias, quasares, pulsares além da existência de todos os elementos que preenchem o espaço cósmico, o vácuo, não mais vazio como se pensou em outros tempos. A mídia explora esse campo de forma mística e também científica. A difusão adequada e dentro dos padrões educacionais vigentes, de conceitos astronômicos, se faz necessária, devido sua presença nos conteúdos escolares, centros de ciência e na mídia, de modo geral. A reforma do Currículo Básico da Escola Pública da maioria dos Estados brasileiros introduziu conceitos astronômicos desde a pré-escola até o Ensino Médio. Num estudo realizado com 1.032 alunos do Ensino Médio de seis escolas estaduais, revelou-se através da aplicação de um questionário que abordava conheciment os básicos em astronomia, como estes foram adquiridos e qual era a infra-estrutura oferecida pela escola: para 66,2% dos entrevistados o professor já fez alguma apresentação a respeito de astronomia. O presente estudo revelou também que 44,5% dos alunos entrevistados adquiriram seus conhecimentos astronômicos na escola, 28,1% através da televisão e 27,4% afirmaram que seus conhecimentos foram obtidos através de outros tipos de mídia (internet, filmes e revistas). Embora o estudo revele claramente que há certo equilíbrio na forma em que os alunos obtiveram seus conhecimentos astronômicos, a mídia ainda explora e muitas vezes desperta o interesse pela astronomia com assuntos que não fazem parte de nosso cotidiano como, por exemplo, o homem na Lua, os projetos espaciais e a primeira viagem de um astronauta brasileiro no espaço. Porém, em certos casos, a mídia pode promover conhecimentos incompletos ou mesmo equivocados sobre os conceitos que envolvam

  11. Terapia de linguagem na afasia

    Directory of Open Access Journals (Sweden)

    Mauro Spinelli

    1977-12-01

    Full Text Available A terapia da linguagem na afasia foi estudada em 15 pacientes, 8 do sexo masculino e 7 do sexo feminino; a idade variou de menos de 10 anos a mais de 50 anos; em 11 casos a afasia era sequela de acidente vascular cerebral e, em 4, de traumatismo crânio-encefálico. Quanto ao tipo de afasia, 5 pacientes apresentavam déficits predominantemente de expressão e 10 apresentavam déficits receptivos e expressivos em graus equiparáveis. Em 6 casos a terapia foi iniciada dentro dos 3 primeiros meses de instalação do quadro; nos restantes foi iniciada mais tardiamente. Dos 15 pacientes, 11 apresentaram evolução satisfatória, a qual não depndeu do grau de afasia, do tipo de afasia, da idade do paciente, do tipo de patologia e do intervalo entre a instalação do quadro afásico e o início da terapia. A terapia da linguagem no paciente afásico é efetiva, o prognóstico não pode ser feito a priori. Somente a evolução do caso com sua retestagem criteriosa poderá dar dados realmente úteis para se falar em evolução.

  12. Extracellular Na+ levels regulate formation and activity of the NaX/alpha1-Na+/K+-ATPase complex in neuronal cells.

    Directory of Open Access Journals (Sweden)

    Emmanuelle eBerret

    2014-12-01

    Full Text Available MnPO neurons play a critical role in hydromineral homeostasis regulation by acting as sensors of extracellular sodium concentration ([Na+]out. The mechanism underlying Na+-sensing involves Na+-flow through the NaX channel, directly regulated by the Na+/K+-ATPase α1-isoform which controls Na+-influx by modulating channel permeability. Together, these two partners form a complex involved in the regulation of intracellular sodium ([Na+]in. Here we aim to determine whether environmental changes in Na+ could actively modulate the NaX/Na+/K+-ATPase complex activity.We investigated the complex activity using patch-clamp recordings from rat MnPO neurons and Neuro2a cells. When the rats were fed with a high-salt-diet, or the [Na+] in the culture medium was increased, the activity of the complex was up-regulated. In contrast, drop in environmental [Na+] decreased the activity of the complex. Interestingly under hypernatremic condition, the colocalization rate and protein level of both partners were up-regulated. Under hyponatremic condition, only NaX protein expression was increased and the level of NaX/Na+/K+-ATPase remained unaltered. This unbalance between NaX and Na+/K+-ATPase pump proportion would induce a bigger portion of Na+/K+-ATPase-control-free NaX channel. Thus we suggest that hypernatremic environment increases NaX/Na+/K+-ATPase α1-isoform activity by increasing the number of both partners and their colocalization rate, whereas hyponatremic environment down-regulates complex activity via a decrease in the relative number of NaX channels controlled by the pump.

  13. Artesanato na terceira idade: um estudo na cidade de Sinop

    Directory of Open Access Journals (Sweden)

    Rosane Marlene Weber

    2012-06-01

    Full Text Available O presente artigo sobre o artesanato e a Terceira Idade, pesquisa realizada em 2011, teve como metodologia o Estudo de Caso do tipo etnográfico. A metodologia de investigação ocorreu por meio de entrevistas semiestruturadas, orais e transcritas, observação e fotografias dos artesanatos em locais de venda e nas residências dos artesãos. Os sujeitos da pesquisa foram: a presidente da Associação da Casa do Artesão de Sinop-MT e oito artesãos. O objetivo foi mostrar a importância do artesanato como atividade educacional e como produtora de autonomia e autoria para os artesãos da Terceira Idade, motivados em realizar este trabalho nesta fase da vida. Para o embasamento teórico utilizou-se obras de Paulo Freire, Moacir Gadotti e sobre a Terceira Idade a coleção de Vivaidade com a organizadora Anita Liberalesso Neri. A análise das entrevistas mostrou que o artesanato traz autonomia educacional quando o idoso busca sozinho aprender sobre o objeto a ser realizado, assim como autonomia financeira, uma vez que a venda do artesanato proporciona certa independência econômica. Em relação ao sentimento de autoria das peças criadas constatou-se muita satisfação e realização, o que motiva a continuar sendo úteis e produtivos na Terceira Idade com muita criatividade. Palavras-chave: educação; terceira idade; artesanato; autonomia; autoria.

  14. Glutamate Water Gates in the Ion Binding Pocket of Na(+) Bound Na(+), K(+)-ATPase

    DEFF Research Database (Denmark)

    Han, Minwoo; Kopec, Wojciech; Solov'yov, Ilia A

    2017-01-01

    III is always protonated. Glutamic acid residues in the three binding sites act as water gates, and their deprotonation triggers water entry to the binding sites. From DFT calculations of Na(+) binding energies, we conclude that three protons in the binding site are needed to effectively bind Na......The dynamically changing protonation states of the six acidic amino acid residues in the ion binding pocket of the Na(+), K(+) -ATPase (NKA) during the ion transport cycle are proposed to drive ion binding, release and possibly determine Na(+) or K(+) selectivity. We use molecular dynamics (MD......(+) from water and four are needed to release them in the next step. Protonation of Asp926 in site III will induce Na(+) release, and Glu327, Glu954 and Glu779 are all likely to be protonated in the Na(+) bound occluded conformation. Our data provides key insights into the role of protons in the Na...

  15. Crystal structure of Na+, K(+)-ATPase in the Na(+)-bound state.

    Science.gov (United States)

    Nyblom, Maria; Poulsen, Hanne; Gourdon, Pontus; Reinhard, Linda; Andersson, Magnus; Lindahl, Erik; Fedosova, Natalya; Nissen, Poul

    2013-10-04

    The Na(+), K(+)-adenosine triphosphatase (ATPase) maintains the electrochemical gradients of Na(+) and K(+) across the plasma membrane--a prerequisite for electrical excitability and secondary transport. Hitherto, structural information has been limited to K(+)-bound or ouabain-blocked forms. We present the crystal structure of a Na(+)-bound Na(+), K(+)-ATPase as determined at 4.3 Å resolution. Compared with the K(+)-bound form, large conformational changes are observed in the α subunit whereas the β and γ subunit structures are maintained. The locations of the three Na(+) sites are indicated with the unique site III at the recently suggested IIIb, as further supported by electrophysiological studies on leak currents. Extracellular release of the third Na(+) from IIIb through IIIa, followed by exchange of Na(+) for K(+) at sites I and II, is suggested.

  16. Elevated arterial blood pressure after superior cavo-pulmonary anastomosis is associated with elevated pulmonary artery pressure and cerebrovascular dysautoregulation.

    Science.gov (United States)

    Cabrera, Antonio G; Kibler, Kathleen K; Blaine Easley, R; Goldsworthy, Michelle; Shekerdemian, Lara S; Andropoulos, Dean B; Heinle, Jeffrey; Gottlieb, Erin A; Vu, Eric; Brady, Ken M

    2018-04-18

    BackgroundElevated arterial blood pressure (ABP) is common after superior bidirectional cavopulmonary anastomosis (BCPA). The effects of elevated ABP after BCPA on cerebrovascular hemodynamics are unknown. We sought to determine the relationship between elevated ABP and cerebrovascular autoregulation after BCPA.MethodsProspective, observational study on infants with single-ventricle physiology after BCPA surgery. Continuous recordings of mean ABP, mean cavopulmonary artery pressure (PAP), near-infrared spectroscopy measures of cerebral oximetry (regional cerebral oxygen saturation (rSO 2 )), and relative cerebral blood volume index were obtained from admission to extubation. Autoregulation was measured as hemoglobin volume index (HVx). Physiologic variables, including the HVx, were tested for variance across ABP.ResultsSixteen subjects were included in the study. Elevated ABP post-BCPA was associated with both, elevated PAP (PABP and alterations in rSO 2 . Using piecewise regression, the relationship of PAP to ABP demonstrated a breakpoint at 68 mm Hg (interquartile range (IQR) 62-70 mm Hg). Curve fit of HVx as a function of ABP identified optimal ABP supporting robust autoregulation at a median ABP of 55 mm Hg (IQR 51-64 mm Hg).ConclusionsElevated ABP post-BCPA is associated with cerebrovascular dysautoregulation, and elevated PAP. The effects, of prolonged dysautoregulation within this population, require further study.Pediatric Research advance online publication, 18 April 2018; doi:10.1038/pr.2018.31.

  17. Laser-induced ionization of Na vapor

    International Nuclear Information System (INIS)

    Wu, R.C.Y.; Judge, D.L.; Roussel, F.; Carre, B.; Breger, P.; Spiess, G.

    1982-01-01

    The production of Na 2 + ions by off-resonant laser excitation in the 5800-6200A region mainly results from two-photon absorption by the Na 2 molecule to highly excited gerade states followed by (a) direct ionization by absorbing a third photon or (b) coupling to the molecular Na 2 D 1 PIμ Rydberg state which is subsequently ionized by absorbing a third photon. This mechanism, i.e., a two-photon resonance three photon ionization process, explains a recent experimental observation of Roussel et al. It is suggested that the very same mechanism is also responsible for a similar observation reported by Polak-Dingels et al in their work using two crossed Na beams. In the latter two studies the laser-induced associative ionization processes were reported to be responsible for producing the Na 2 + ion. From the ratio of molecular to atomic concentration in the crossed beam experiment of Polak-Dingels et al we estimate that the cross section for producing Na 2 + through laser-induced associative ionization is at least four orders of magnitude smaller than ionization through the two-photon resonance three photon ionization process in Na 2 molecules

  18. NaK handling and removal

    International Nuclear Information System (INIS)

    Desreumaux, J.; Rodriguez, G.; Guigon, A.; Verdelli, J.; Thomine, G.

    1997-01-01

    Sodium-potassium alloy is used in specific application in French Fast Breeder Reactors as: cold traps, NaK bubbler for argon purification, valves and also in experimental irradiation devices. lt has been preferred to sodium because it is liquid from + 7 deg. C for the most common peritectic alloy. After its use, NaK is considered as a hazardous waste (nuclear or not) due to its high reactivity with air and water. The most important risk remains in handling NaK systems which have not been operated for some time. The NaK will be covered with a crust of the superoxide K02 which is a strong oxidising agent. Thermodynamically, K02 will react with most organic material or metallic dust or swarfs and can also react with additional NaK to give sufficient heat to boil part of the NaK, resulting in a sudden increase in pressure and small explosions. We describe the formation given to experimenters in our Sodium School and the CEA's experience in treating specific devices for transportation, decanting of tanks, tank opening and NaK removal. (author)

  19. Na/K pump inactivation, subsarcolemmal Na measurements, and cytoplasmic ion turnover kinetics contradict restricted Na spaces in murine cardiac myocytes

    OpenAIRE

    Lu, Fang-Min; Hilgemann, Donald W.

    2017-01-01

    The Na/K pump exports cytoplasmic Na ions while importing K ions, and its activity is thought to be affected by restricted intracellular Na diffusion in cardiac myocytes. Lu and Hilgemann find instead that the pump can enter an inactivated state and that inactivation can be relieved by cytoplasmic Na.

  20. MODELI MERJENJA KAKOVOSTI STORITEV NA MEDORGANIZACIJSKEM TRGU

    OpenAIRE

    Cestnik, Dušan

    2011-01-01

    Vse večja konkurenca na medorganizacijskih trgih sili tako storitvena podjetja, kot tudi podjetja, ki tržijo izdelke, da svoje delo opravljajo vse bolj kakovostno na vseh ravneh svojega delovanja. Podjetja morajo svoje odjemalce obdržati, prav tako pa morajo delovati tudi na pridobivanju novih odjemalcev. Da pa podjetja svoje odjemalce obdržijo morajo nenehno delovati tako, da uživajo zaupanje svojih odjemalcev. Odjemalec že z odločitvijo za neko določeno podjetje XY pričakuje, da bodo storit...

  1. Na+,K+ pumpen vedbliver at overraske

    DEFF Research Database (Denmark)

    Vilsen, Bente

    2008-01-01

    This article provides an overview of news about the Na+,K+ pump, an indispensable enzyme whose protein structure has been described in a recent article in Nature, 50 years after its discovery. In combination with mutational analysis, the structure reveals the binding pocket for the K+ ions...... and the regulation of Na+ transport by a strategically located C-terminus of the protein. Focus is also on the pathophysiology of two neurological disorders, familial hemiplegic migraine and rapid-onset dystonia-parkinsonism, recently shown to be caused by mutations in the Na+,K+-ATPase. Udgivelsesdato: may 19...

  2. Myocardial Na,K-ATPase: Clinical aspects

    Science.gov (United States)

    Kjeldsen, Keld

    2003-01-01

    The specific binding of digitalis glycosides to Na,K-ATPase is used as a tool for Na,K-ATPase quantification with high accuracy and precision. In myocardial biopsies from patients with heart failure, total Na,K-ATPase concentration is decreased by around 40%; a correlation exists between a decrease in heart function and a decrease in Na,K-ATPase concentration. During digitalization, around 30% of remaining pumps are occupied by digoxin. Myocardial Na,K-ATPase is also influenced by other drugs used for the treatment of heart failure. Thus, potassium loss during diuretic therapy has been found to reduce myocardial Na,K-ATPase, whereas angiotensin-converting enzyme inhibitors may stimulate Na,K pump activity. Furthermore, hyperaldosteronism induced by heart failure has been found to decrease Na,K-ATPase activity. Accordingly, treatment with the aldosterone antagonist, spironolactone, may also influence Na,K-ATPase activity. The importance of Na,K pump modulation with heart disease, inhibition in digitalization and other effects of medication should be considered in the context of sodium, potassium and calcium regulation. It is recommended that digoxin be administered to heart failure patients who, after institution of mortality-reducing therapy, still have heart failure symptoms, and that the therapy be continued if symptoms are revealed or reduced. Digitalis glycosides are the only safe inotropic drugs for oral use that improve hemodynamics in heart failure. An important aspect of myocardial Na,K pump affection in heart disease is its influence on extracellular potassium (Ke) homeostasis. Two important aspects should be considered: potassium handling among myocytes, and effects of potassium entering the extracellular space of the heart via the bloodstream. It should be noted that both of these aspects of Ke homeostasis are affected by regulatory aspects, eg, regulation of the Na,K pump by physiological and pathophysiological conditions, as well as by medical

  3. Nalaz tombusvirusa na vrsti Erigeron canadensis L.

    OpenAIRE

    Jeknić, Zoran; Erić, Živojin; Grbelja, Julijana

    1988-01-01

    Iz listova zaraženih primjeraka korovne biljke Erigeron canadensis L. koji su rasli na nekoliko lokaliteta u Sarajevu izoliran je virus iz skupine tombusvirusi. Identifikacija virusa izvršena je na osnovi reakcije pokusnih biljaka, analize ultratankih presjeka kroz zaraženo tkivo, morfologije i veličine virusnih čestica, te na osnovi seroloških reakcija metodom dvostruke imunodifuzije u agarskom gelu i čvrsto fazne imunoelektronske mikroskopije (SPIEM). U serološkim pokusima upotrijebljen je ...

  4. Glutathionylation-Dependence of Na+-K+-Pump Currents Can Mimic Reduced Subsarcolemmal Na+ Diffusion

    Science.gov (United States)

    Garcia, Alvaro; Liu, Chia-Chi; Cornelius, Flemming; Clarke, Ronald J.; Rasmussen, Helge H.

    2016-01-01

    The existence of a subsarcolemmal space with restricted diffusion for Na+ in cardiac myocytes has been inferred from a transient peak electrogenic Na+-K+ pump current beyond steady state on reexposure of myocytes to K+ after a period of exposure to K+-free extracellular solution. The transient peak current is attributed to enhanced electrogenic pumping of Na+ that accumulated in the diffusion-restricted space during pump inhibition in K+-free extracellular solution. However, there are no known physical barriers that account for such restricted Na+ diffusion, and we examined if changes of activity of the Na+-K+ pump itself cause the transient peak current. Reexposure to K+ reproduced a transient current beyond steady state in voltage-clamped ventricular myocytes as reported by others. Persistence of it when the Na+ concentration in patch pipette solutions perfusing the intracellular compartment was high and elimination of it with K+-free pipette solution could not be reconciled with restricted subsarcolemmal Na+ diffusion. The pattern of the transient current early after pump activation was dependent on transmembrane Na+- and K+ concentration gradients suggesting the currents were related to the conformational poise imposed on the pump. We examined if the currents might be accounted for by changes in glutathionylation of the β1 Na+-K+ pump subunit, a reversible oxidative modification that inhibits the pump. Susceptibility of the β1 subunit to glutathionylation depends on the conformational poise of the Na+-K+ pump, and glutathionylation with the pump stabilized in conformations equivalent to those expected to be imposed on voltage-clamped myocytes supported this hypothesis. So did elimination of the transient K+-induced peak Na+-K+ pump current when we included glutaredoxin 1 in patch pipette solutions to reverse glutathionylation. We conclude that transient K+-induced peak Na+-K+ pump current reflects the effect of conformation-dependent β1 pump subunit

  5. Altered Na+ transport after an intracellular alpha-subunit deletion reveals strict external sequential release of Na+ from the Na/K pump.

    Science.gov (United States)

    Yaragatupalli, Siddhartha; Olivera, J Fernando; Gatto, Craig; Artigas, Pablo

    2009-09-08

    The Na/K pump actively exports 3 Na(+) in exchange for 2 K(+) across the plasmalemma of animal cells. As in other P-type ATPases, pump function is more effective when the relative affinity for transported ions is altered as the ion binding sites alternate between opposite sides of the membrane. Deletion of the five C-terminal residues from the alpha-subunit diminishes internal Na(+) (Na(i)(+)) affinity approximately 25-fold [Morth et al. (2007) Nature 450:1043-1049]. Because external Na(+) (Na(o)(+)) binding is voltage-dependent, we studied the reactions involving this process by using two-electrode and inside-out patch voltage clamp in normal and truncated (DeltaKESYY) Xenopus-alpha1 pumps expressed in oocytes. We observed that DeltaKESYY (i) decreased both Na(o)(+) and Na(i)(+) apparent affinities in the absence of K(o)(+), and (ii) did not affect apparent Na(o)(+) affinity at high K(o)(+). These results support a model of strict sequential external release of Na(+) ions, where the Na(+)-exclusive site releases Na(+) before the sites shared with K(+) and the DeltaKESYY deletion only reduces Na(o)(+) affinity at the shared sites. Moreover, at nonsaturating K(o)(+), DeltaKESYY induced an inward flow of Na(+) through Na/K pumps at negative potentials. Guanidinium(+) can also permeate truncated pumps, whereas N-methyl-D-glucamine cannot. Because guanidinium(o)(+) can also traverse normal Na/K pumps in the absence of both Na(o)(+) and K(o)(+) and can also inhibit Na/K pump currents in a Na(+)-like voltage-dependent manner, we conclude that the normal pathway transited by the first externally released Na(+) is large enough to accommodate guanidinium(+).

  6. Erythrocyte 22Na+ influx in hypertension

    International Nuclear Information System (INIS)

    Shalev, O.; Eaton, J.W.; Ben-Ishay, D.

    1984-01-01

    We assessed 22Na+ uptake by erythrocytes (RBC) from 38 individuals with essential hypertension and 37 healthy controls. All subjects were male, white, non-obese and with normal renal function, obviating sex, race, hormonal, ponderal and renal factors known to influence RBC Na+ handling. The mean +/- sem 22Na+ uptake of the patients was 284 +/- 16 mumole/liter RBC/hour while that of normal controls was 249 +/- 11 mumole/liter RBC/hour; although the difference reached borderline significance, individual values showed considerable overlap. Consequently, in our population, RBC 22Na+ uptake is not a reliable marker for essential hypertension. We believe that previous studies should be reassessed with regard to patients' characteristics and future studies employ rigorous criteria in selection of subjects

  7. Painful Na-channelopathies: an expanding universe.

    Science.gov (United States)

    Waxman, Stephen G

    2013-07-01

    The universe of painful Na-channelopathies--human disorders caused by mutations in voltage-gated sodium channels--has recently expanded in three dimensions. We now know that mutations of sodium channels cause not only rare genetic 'model disorders' such as inherited erythromelalgia and channelopathy-associated insensitivity to pain but also common painful neuropathies. We have learned that mutations of NaV1.8, as well as mutations of NaV1.7, can cause painful Na-channelopathies. Moreover, recent studies combining atomic level structural models and pharmacogenomics suggest that the goal of genomically guided pain therapy may not be unrealistic. Copyright © 2013 Elsevier Ltd. All rights reserved.

  8. Usmerjanje urbanega razvoja na mestni ravni

    Directory of Open Access Journals (Sweden)

    Mojca Šašek Divjak

    1999-01-01

    Full Text Available Kot je poudarjeno v predstavljenem načrtu Kopenhagna, mestni načrt ne more rešiti vseh planskih problemov mesta. Predstavljal naj bi predvideni red, ki pa se pogosto sproti podira glede na nepredvidena dogajanja v prostoru. Probleme je velikokrat treba reševati šele, ko se pokažejo. Zato mora biti mestni načrt zastavljen dovolj prilagodljivo in fleksibilno, da dovoljuje potrebne spremembe. Vendar mora kljub temu dati mestu trdne glavne usmeritve in s tem omogočiti, da meščani lahko izkoristijo priložnosti, ki jih nudi nova doba in uveljavljajo nove kvalitete bivanja.

  9. Na+-H+ exchange and Na+-dependent transport systems in streptozotocin diabetic rat kidneys

    International Nuclear Information System (INIS)

    El-Seifi, S.; Freiberg, J.M.; Kinsella, F.J.; Cheng, L.; Sacktor, B.

    1987-01-01

    The streptozotocin-induced diabetic rat was used to test the hypothesis that Na + -H + exchange activity in the proximal tubule luminal membrane would be increased in association with renal hypertrophy, altered glomerular hemodynamics, enhanced filtered load and tubular reabsorption of 22 Na + , and stimulated 22 Na= pump activity in the basolateral membrane, previously reported characteristics of this experimental animal model. Amiloride-sensitive H + gradient-dependent Na + uptake and Na + gradient-dependent H + flux were increased in brush-border membrane vesicles from the streptozotocin-treated animals. Na + gradient-dependent uptakes of phosphate, D-glucose, L-proline, and myoinositol were decreased in the drug-induced diabetic animals. These membrane transport alterations were not found when the streptozotocin-diabetic animals were treated with insulin

  10. Effects of EDTA-Na (Na ethylenediaminetetraacetate) upon the metabolism of radiostrontium and radioyttrium in mice

    Energy Technology Data Exchange (ETDEWEB)

    Kikuchi, T; Wakisaka, G; Kono, T; Hiroaki, A; Yamamasu, T; Sugawa, I

    1954-01-01

    The toxicity of EDTA-Na, inert Sr (NO/sub 3/)/sub 2/ and Ba (NO/sub 3/)/sub 2/ has been examined. Simultaneous injection of EDTA-Na showed no significant effect upon the distribution of radio-Sr in the bones of mice. The distribution of radio-Y in the bones of mice tended to decrease following the simultaneous subcutaneous injection of /sup 91/Y and EDTA-Na.

  11. Glutathionylation-Dependence of Na+-K+-Pump Currents Can Mimic Reduced Subsarcolemmal Na+ Diffusion

    OpenAIRE

    Garcia, Alvaro; Liu, Chia-Chi; Cornelius, Flemming; Clarke, Ronald?J.; Rasmussen, Helge?H.

    2016-01-01

    The existence of a subsarcolemmal space with restricted diffusion for Na+ in cardiac myocytes has been inferred from a transient peak electrogenic Na+-K+ pump current beyond steady state on reexposure of myocytes to K+ after a period of exposure to K+-free extracellular solution. The transient peak current is attributed to enhanced electrogenic pumping of Na+ that accumulated in the diffusion-restricted space during pump inhibition in K+-free extracellular solution. However, there are no know...

  12. NA62 and NA48/2 results on search for Heavy Neutral Leptons

    Directory of Open Access Journals (Sweden)

    Lamanna Gianluca

    2018-01-01

    Full Text Available In this paper we present new results on upper limits for the search of Heavy Neutral Leptons (HNL with data collected by NA48/2 (2003-2004, NA62-RK (2007 and NA62 (2015 CERN experiments. The data collected with different trigger configuration allow to search for both long and short living heavy neutrinos in the mass range below the kaon mass. In addition the status of the search for K+ → π+vv with the NA62 detector will be briefly presented.

  13. Interaction between Na+/K+-pump and Na+/Ca2+-exchanger modulates intercellular communication.

    Science.gov (United States)

    Matchkov, Vladimir V; Gustafsson, Helena; Rahman, Awahan; Briggs Boedtkjer, Donna M; Gorintin, Sarah; Hansen, Anne Kirstine; Bouzinova, Elena V; Praetorius, Helle A; Aalkjaer, Christian; Nilsson, Holger

    2007-04-13

    Ouabain, a specific inhibitor of the Na(+)/K(+)-pump, has previously been shown to interfere with intercellular communication. Here we test the hypothesis that the communication between vascular smooth muscle cells is regulated through an interaction between the Na(+)/K(+)-pump and the Na(+)/Ca(2+)-exchanger leading to an increase in the intracellular calcium concentration ([Ca(2+)](i)) in discrete areas near the plasma membrane. [Ca(2+)](i) in smooth muscle cells was imaged in cultured rat aortic smooth muscle cell pairs (A7r5) and in rat mesenteric small artery segments simultaneously with force. In A7r5 coupling between cells was estimated by measuring membrane capacitance. Smooth muscle cells were uncoupled when the Na(+)/K(+)-pump was inhibited either by a low concentration of ouabain, which also caused a localized increase of [Ca(2+)](i) near the membrane, or by ATP depletion. Reduction of Na(+)/K(+)-pump activity by removal of extracellular potassium ([K(+)](o)) also uncoupled cells, but only after inhibition of K(ATP) channels. Inhibition of the Na(+)/Ca(2+)-exchange activity by SEA0400 or by a reduction of the equilibrium potential (making it more negative) also uncoupled the cells. Depletion of intracellular Na(+) and clamping of [Ca(2+)](i) at low concentrations prevented the uncoupling. The experiments suggest that the Na(+)/K(+)-pump may affect gap junction conductivity via localized changes in [Ca(2+)](i) through modulation of Na(+)/Ca(2+)-exchanger activity.

  14. Na5NbO5 and Na5TaO5 phases

    International Nuclear Information System (INIS)

    Darriet, J.; Maazaz, A.; Bouloux, J.C.; Delmas, C.

    1982-01-01

    New ternary oxides of formulas Na 5 NbO 5 and Na 5 TaO 5 have been prepared. They crystallize in the monoclinic system (space group C2/c). The crystal structure of Na 5 NbO 5 has been determined. It derives from a NaCl-type structure by ordering of the cations and of the oxygen vacancies in the anionic sublattice, the corresponding formula being Nasub(5/6)Nbsub(1/6)Osub(5/6)vacant sub(1/6). Sodium and niobium have a distorted square-pyramidal surrounding. (author)

  15. Suppression of Na interstitials in Na-F codoped ZnO

    Science.gov (United States)

    Huo, Wenxing; Mei, Zengxia; Tang, Aihua; Liang, Huili; Du, Xiaolong

    2018-04-01

    Controlling the formation of interstitial Na (Nai) self-compensating defects has been a long-term physics problem for effective Na doping in ZnO. Herein, we present an experimental approach to the suppression of Nai defects in ZnO via Na and F codoping under an oxygen-rich condition during the molecular beam epitaxy growth process. It is found that the incorporation of such large numbers of Na and F dopants (˜1020 cm-3) does not cause an obvious influence on the lattice parameters. Hall-effect measurements demonstrate that F doping efficiently raises the Fermi level (EF) of ZnO films, which is expected to make the formation energy of Nai and NaZn increase and decrease, respectively. Most of the Na atoms occupy the substitutional Zn sites, and the formation of Nai is suppressed consequently. Secondary ion mass spectrometry measurements reveal that F and Na atoms are tightly bonded together due to their strong Coulomb interaction. The enhanced deep level emission (DLE) in ZnO:Na-F is ascribed to the considerable amount of isolated Zn vacancy (VZn) defects induced by the elevated EF and the formation of neutral (" separators="| FO + - Na Zn - ) 0 complexes. On the other hand, formation of (" separators="| FO + - VZn 2 - ) - complexes in ZnO:F exhausts most of the isolated Zn vacancies, leading to the disappearance of the DLE band.

  16. MOŽNOSTI VSTOPA NA TUJE TRGE NA PRIMERU PODJETJA AWOODTURE

    OpenAIRE

    Orličnik, Urša

    2014-01-01

    Danes pojavljanje podjetja samo na domačem trgu ni več dovolj. Spremembe okolja, naraščanje konkurence ter hiter tehnološki napredek, silijo podjetja k nenehnemu prilagajanju in iskanju novih priložnosti tako na domačem kot tudi na tujem trgu. Internacionalizacija podjetja tako postaja vedno bolj pomemembna za preživetje podjetja. Internacionalizacija se v najširšem smislu nanaša na vse oblike mednarodnega ekonomskega sodelovanja. Je dinamičen proces, kateremu nujno sledi sprememba stanja...

  17. Elastic Coulomb breakup of 34Na

    Science.gov (United States)

    Singh, G.; Shubhchintak, Chatterjee, R.

    2016-08-01

    Background: 34Na is conjectured to play an important role in the production of seed nuclei in the alternate r -process paths involving light neutron rich nuclei very near the β -stability line, and as such, it is important to know its ground state properties and structure to calculate rates of the reactions it might be involved in, in the stellar plasma. Found in the region of `island of inversion', its ground state might not be in agreement with normal shell model predictions. Purpose: The aim of this paper is to study the elastic Coulomb breakup of 34Na on 208Pb to give us a core of 33Na with a neutron and in the process we try and investigate the one neutron separation energy and the ground state configuration of 34Na. Method: A fully quantum mechanical Coulomb breakup theory within the architecture of post-form finite range distorted wave Born approximation extended to include the effects of deformation is used to research the elastic Coulomb breakup of 34Na on 208Pb at 100 MeV/u. The triple differential cross section calculated for the breakup is integrated over the desired components to find the total cross-section, momentum, and angular distributions as well as the average momenta, along with the energy-angular distributions. Results: The total one neutron removal cross section is calculated to test the possible ground state configurations of 34Na. The average momentum results along with energy-angular calculations indicate 34Na to have a halo structure. The parallel momentum distributions with narrow full widths at half-maxima signify the same. Conclusion: We have attempted to analyze the possible ground state configurations of 34Na and in congruity with the patterns in the `island of inversion' conclude that even without deformation, 34Na should be a neutron halo with a predominant contribution to its ground state most probably coming from 33Na(3 /2+)⊗ 2 p3 /2ν configuration. We also surmise that it would certainly be useful and rewarding to test our

  18. Clues to NaCN formation

    Science.gov (United States)

    Quintana-Lacaci, G.; Cernicharo, J.; Velilla Prieto, L.; Agúndez, M.; Castro-Carrizo, A.; Fonfría, J. P.; Massalkhi, S.; Pardo, J. R.

    2017-11-01

    Context. ALMA is providing us essential information on where certain molecules form. Observing where these molecules emission arises from, the physical conditions of the gas, and how this relates with the presence of other species allows us to understand the formation of many species, and to significantly improve our knowledge of the chemistry that occurs in the space. Aims: We studied the molecular distribution of NaCN around IRC +10216, a molecule detected previously, but whose origin is not clear. High angular resolution maps allow us to model the abundance distribution of this molecule and check suggested formation paths. Methods: We modeled the emission of NaCN assuming local thermal equilibrium (LTE) conditions. These profiles were fitted to azimuthal averaged intensity profiles to obtain an abundance distribution of NaCN. Results: We found that the presence of NaCN seems compatible with the presence of CN, probably as a result of the photodissociation of HCN, in the inner layers of the ejecta of IRC +10216. However, similar as for CH3CN, current photochemical models fail to reproduce this CN reservoir. We also found that the abundance peak of NaCN appears at a radius of 3 × 1015 cm, approximately where the abundance of NaCl, suggested to be the parent species, starts to decay. However, the abundance ratio shows that the NaCl abundance is lower than that obtained for NaCN. We expect that the LTE assumption might result in NaCN abundances higher than the real ones. Updated photochemical models, collisional rates, and reaction rates are essential to determine the possible paths of the NaCN formation. Based on observations carried out with ALMA and the IRAM 30 m Telescope. ALMA is a partnership of ESO (representing its member states), NSF (USA) and NINS (Japan), together with NRC (Canada) and NSC and ASIAA (Taiwan), in cooperation with the Republic of Chile. The Joint ALMA Observatory is operated by ESO, AUI/NRAO and NAOJ. IRAM is supported by INSU/CNRS (France

  19. HCO3(-)-coupled Na+ influx is a major determinant of Na+ turnover and Na+/K+ pump activity in rat hepatocytes

    International Nuclear Information System (INIS)

    Fitz, J.G.; Lidofsky, S.D.; Weisiger, R.A.; Xie, M.H.; Cochran, M.; Grotmol, T.; Scharschmidt, B.F.

    1991-01-01

    Recent studies in hepatocytes indicate that Na(+)-coupled HCO3- transport contributes importantly to regulation of intracellular pH and membrane HCO3- transport. However, the direction of net coupled Na+ and HCO3- movement and the effect of HCO3- on Na+ turnover and Na+/K+ pump activity are not known. In these studies, the effect of HCO3- on Na+ influx and turnover were measured in primary rat hepatocyte cultures with 22Na+, and [Na+]i was measured in single hepatocytes using the Na(+)-sensitive fluorochrome SBFI. Na+/K+ pump activity was measured in intact perfused rat liver and hepatocyte monolayers as Na(+)-dependent or ouabain-suppressible 86Rb uptake, and was measured in single hepatocytes as the effect of transient pump inhibition by removal of extracellular K+ on membrane potential difference (PD) and [Na+]i. In hepatocyte monolayers, HCO3- increased 22Na+ entry and turnover rates by 50-65%, without measurably altering 22Na+ pool size or cell volume, and HCO3- also increased Na+/K+ pump activity by 70%. In single cells, exposure to HCO3- produced an abrupt and sustained rise in [Na+]i from approximately 8 to 12 mM. Na+/K+ pump activity assessed in single cells by PD excursions during transient K+ removal increased congruent to 2.5-fold in the presence of HCO3-, and the rise in [Na+]i produced by inhibition of the Na+/K+ pump was similarly increased congruent to 2.5-fold in the presence of HCO3-. In intact perfused rat liver, HCO3- increased both Na+/K+ pump activity and O2 consumption. These findings indicate that, in hepatocytes, net coupled Na+ and HCO3- movement is inward and represents a major determinant of Na+ influx and Na+/K+ pump activity. About half of hepatic Na+/K+ pump activity appears dedicated to recycling Na+ entering in conjunction with HCO3- to maintain [Na+]i within the physiologic range

  20. Coulomb excitation of radioactive 20, 21Na

    Science.gov (United States)

    Schumaker, M. A.; Cline, D.; Hackman, G.; Pearson, C.; Svensson, C. E.; Wu, C. Y.; Andreyev, A.; Austin, R. A. E.; Ball, G. C.; Bandyopadhyay, D.; Becker, J. A.; Boston, A. J.; Boston, H. C.; Buchmann, L.; Churchman, R.; Cifarelli, F.; Cooper, R. J.; Cross, D. S.; Dashdorj, D.; Demand, G. A.; Dimmock, M. R.; Drake, T. E.; Finlay, P.; Gallant, A. T.; Garrett, P. E.; Green, K. L.; Grint, A. N.; Grinyer, G. F.; Harkness, L. J.; Hayes, A. B.; Kanungo, R.; Lisetskiy, A. F.; Leach, K. G.; Lee, G.; Maharaj, R.; Martin, J.-P.; Moisan, F.; Morton, A. C.; Mythili, S.; Nelson, L.; Newman, O.; Nolan, P. J.; Orce, J. N.; Padilla-Rodal, E.; Phillips, A. A.; Porter-Peden, M.; Ressler, J. J.; Roy, R.; Ruiz, C.; Sarazin, F.; Scraggs, D. P.; Waddington, J. C.; Wan, J. M.; Whitbeck, A.; Williams, S. J.; Wong, J.

    2009-12-01

    The low-energy structures of the radioactive nuclei 20, 21Na have been examined using Coulomb excitation at the TRIUMF-ISAC radioactive ion beam facility. Beams of ˜ 5×106 ions/s were accelerated to 1.7MeV/A and Coulomb excited in a 0.5mg/cm^2 natTi target. Two TIGRESS HPGe clover detectors perpendicular to the beam axis were used for γ -ray detection, while scattered nuclei were observed by the Si detector BAMBINO. For 21Na , Coulomb excitation from the 3/2+ ground state to the first excited 5/2+ state was observed, while for 20Na , Coulomb excitation was observed from the 2+ ground state to the first excited 3+ and 4+ states. For both beams, B ( λ L) values were determined using the 2+ rightarrow 0+ de-excitation in 48Ti as a reference. The resulting B( E2) ↓ value for 21Na is 137±9 e^2fm^4, while the resulting B( λ L) ↓ values for 20Na are 55±6 e^2fm^4 for the 3+ rightarrow 2+ , 35.7±5.7 e^2 fm^4 for the 4+ rightarrow 2+ , and 0.154±0.030 μ_ N^2 for the 4+ rightarrow 3+ transitions. This analysis significantly improves the measurement of the 21Na B( E2) value, and provides the first experimental determination of B( λ L) values for the proton dripline nucleus 20Na .-1

  1. The plant vacuolar Na+/H+ antiport.

    Science.gov (United States)

    Barkla, B J; Apse, M P; Manolson, M F; Blumwald, E

    1994-01-01

    Salt stress imposes severe limitations on plant growth, however, the extent of growth reduction depends upon the soil salinity level and the plant species. One of the mechanisms employed by salt tolerant plants is the effective vacuolar compartmentalization of sodium. The sequestration of sodium into the vacuole occurs by the operation of a Na+/H+ antiport located at the tonoplast. Evidence for a plant vacuolar Na+/H+ antiport has been demonstrated in tissues, intact vacuoles and isolated tonoplast vesicles. In sugar beet cell suspensions, the activity of the vacuolar Na+/H+ antiport increased with increasing NaCl concentrations in the growth medium. This increased activity was correlated with the increased synthesis of a 170 kDa tonoplast polypeptide. In vivo labelling of tonoplast proteins showed the enhanced synthesis of the 170 kDa polypeptide not only upon exposure of the cells to salt, but also when the cells were grown in the presence of amiloride. Exposure of the cells to amiloride also resulted in increased vacuolar Na+/H+ antiport activity. Polyclonal antibodies raised against the 170 kDa polypeptide almost completely inhibited the antiport activity, suggesting the association of this protein with the plant vacuolar Na+/H+ antiport. Antibodies against the Na+/H+ antiport-associated polypeptide were used to screen a Beta lambda ZAP expression library. A partial clone of 1.65 kb was sequenced and found to encode a polypeptide with a putative transmembrane domain and a large hydrophilic C terminus. This clone showed no homology to any previously cloned gene at either the nucleic acid or the amino acid level.

  2. TweetNaCl : a crypto library in 100 tweets

    NARCIS (Netherlands)

    Bernstein, D.J.; van Gastel, B.; Janssen, W.; Lange, T.; Schwabe, P.; Smetsers, S.; Aranha, D.F.; Menezes, A.

    2015-01-01

    This paper introduces TweetNaCl, a compact reimplementation of the NaCl library, including all 25 of the NaCl functions used by applications. TweetNaCl is published on Twitter and fits into just 100 tweets; the tweets are available from anywhere, any time, in an unsuspicious way. Distribution via

  3. Kupokelewa Zaidi Kwa Simu Ya Mkononi Kuliko Kompyuta Na ...

    African Journals Online (AJOL)

    Mtandao wa tovuti ni nyenzo ya msingi katika maendeleo ya uwanja wa mawasiliano unaounganisha watu na jamii mbalimbali katika ulimwengu wa leo unaotandawaa. Katika “ulimwengu wa kwanza na wa pili”, yaani mabara ya Amerika, Uropa na Asia, maendeleo na mapinduzi makubwa katika uwanja wa teknolojia ya ...

  4. Mabadiliko Ya Kifonolojia Na Kimofolojia Wakati Wa Utohozi Wa ...

    African Journals Online (AJOL)

    Mwingiliano wa lugha ya Kiswahili na Kiarabu una historia ndefu kidogo. Inasemekana Waarabu walianza muwasala na 'Waswahili' tangu karne ya kwanza (BK) (Polome 1967:9). Kutokana na muwasala huo wa muda mrefu, lugha hizi mbili (Kiarabu na Kiswahili) zimeathiriana sana. Lakini kuna maoni kwamba Kiarabu ...

  5. O Passeio Público do Rio de Janeiro na Literatura, na Pintura e na Fotografia do Século XIX

    Directory of Open Access Journals (Sweden)

    Solange de Aragão

    2012-06-01

    Full Text Available Este artigo tem como objetivo geral e mais amplo chamar a atenção dos pesquisadores para a importância da literatura, da pintura e da fotografia como fontes documentais para a construção da História do Paisagismo no Brasil por meio de um estudo de caso muito particular: o Passeio Público do Rio de Janeiro no século XIX. São objetivos específicos apresentar e analisar o modo como esse espaço livre público aparece na literatura, na pintura e na fotografia desse período, considerando suas transformações paisagísticas.

  6. Hibridismo cultural: o imaginário europeu na construção da sexualidade feminina do primeiro século de colonização brasileira

    Directory of Open Access Journals (Sweden)

    Anne Caroline Mariank Alves Scalia

    2012-02-01

    Full Text Available O objetivo deste trabalho é investigar e analisar as concepções acerca da sexualidade e de comportamentos e condutas sexuais femininas, formados a partir da incorporação de informações e valores adquiridos sob o olhar, regras e relações estabelecidas com as orientações do Santo Ofício Inquisitorial em sua visita ao Brasil no final do século XVI. É uma pesquisa de cunho histórico em que utilizamos como metodologia a pesquisa exploratória e bibliográfica. No século XVI aumenta a pressão da Igreja para mudar os costumes sexuais que eram livres na Idade Média, fato que influencia as regras e normas que serão adotadas pelo Santo Ofício no tocante à vida sexual das pessoas. A primeira estrutura sexual brasileira foi pautada na aliança entre índios e colonizadores, o que levou a adoço, por parte dos portugueses, dos costumes da terra, que incluíam práticas sexuais livres, já que os indígenas estavam fora da influência cristã. Reforçados pela ausência de mulheres brancas, os colonizadores tomavam para si mulheres da terra, geralmente mais de uma, criando confronto com os jesuítas que condenavam a poligamia indígena. É neste contexto que, em 1591, desembarca em terras brasileiras Heitor Furtado de Mendonça e, com ele, a Primeira Visitação do Santo Ofício, para investigar, argüir, devassar ânimos e comportamentos, descobrir a verdade dos fatos, enfim, para demonstrar os erros da fé e puni-los com o rigor da lei eclesiástica. Sua passagem abre-nos vestígios para a visualização da sexualidade vigente no “trópico”: um universo misóginoracista em que negras da terra e mulheres degradadas podiam ser submetidas aos desejos do homem branco, com as quais podia copular a vontade. Sozinhas e esquecidas, as mulheres da Colônia não encontraram margem para denunciar ou se expressar e eram estigmatizadas pelo olhar dos viajantes e cronistas que por aqui passaram.

  7. Reflexões sobre Água, Sabão e Conhecimento: Aprendizagem Organizacional na prática das serventes de limpeza de uma instituição de ensino federal

    Directory of Open Access Journals (Sweden)

    VIVIANI TEODORO SANTOS

    2017-06-01

    Full Text Available Em razão da multiplicidade de abordagens e da complexidade do tema, a Aprendizagem Organizacional, dificilmente poderia ser entendida por meio de conceitos únicos ou estanques. Um mundo de desafios e possibilidades se abre no estudo da temática e, refletir sobre os diversos caminhos, faz parte do próprio processo de aproximação do tema. Sendo assim, o presente artigo tem como objetivo conhecer a prática cotidiana das serventes de limpeza de uma instituição de ensino federal apoiando-se em diferentes abordagens da Aprendizagem, na tentativa de responder quatro perguntas: 1. Como as serventes aprendem? 2. Quais as implicações na aprendizagem, o fato de se tratar de serviço terceirizado? 3. Qual a capacidade de interferência da gestão no processo de aprendizagem? e 4. Como conduzir o processo de aprendizagem para solucionar a problemática? Por meio de uma pesquisa qualitativa, marcada por mais de um momento de coleta de dados e pela experiência da autoconfrontação simples, percebe-se que o conhecimento adquirido e utilizado pelo grupo provém de uma prática cotidiana fortemente vinculada às suas histórias de vida, e que, até o momento, a gestão não tem obtido sucesso nas tentativas de implantação de melhorias. Neste sentido, entende-se que uma alternativa apropriada para um futuro trabalho seria a opção por metodologias intervencionistas, em razão de serem capazes de proporcionar um espaço de reflexão e participação, em que as contradições possam ser trabalhadas de forma cíclica, transformando os envolvidos em sujeitos ativos e autores da própria trajetória de mudanças, tanto no âmbito profissional quanto pessoal.

  8. VPLIV CENE NA ZADOVOLJSTVO IN ZVESTOBO UPORABNIKOV TELEKOMUNIKACIJSKIH STORITEV

    OpenAIRE

    Majcen, Mateja

    2016-01-01

    Cena izdelka ali storitve, ki jo plača uporabnik, ima pomemben vpliv na zadovoljstvo ali nezadovoljstvo uporabnika z uporabo tega izdelka ali storitve in posledično na zadovoljstvo do podjetja. Glede na to, da se različni avtorji strinjajo in to tudi dokazujejo z raziskavami, zadovoljstvo nedvoumno vpliva na zvestobo uporabnika, zvestoba pa na dolgoročno uspešnost podjetja, smo v delu ugotavljali, kako sama cena storitve vpliva na zadovoljstvo in kako posredno preko zadovoljstva vpliva na zve...

  9. Molecular dynamics investigation of Na+ in Na2Ni2TeO6

    International Nuclear Information System (INIS)

    Sau, Kartik; Kumar, P. Padma

    2014-01-01

    An inter-atomic potential for Na 2 Ni 2 TeO 6 in the Parrinello- Rahman-Vashishta (PRV) model is parameterized empirically. The potential reproduces variety of structural and transport properties of that material in good agreement with recent experimental results. The study provides fresh insights on the migration channels and mechanism of Na + in the system

  10. Muziki wa Hip Hop na Haki Za Kijamii: Dhima, Changamoto na ...

    African Journals Online (AJOL)

    Ni dhahiri kuwa haki za kijamii zinaweza kuwasilishwa kwa jamii pana kupitia sanaa ya hip hop. Makala haya basi, yanabainisha dhima na mchango wa muziki wa hip hop katika masuala ya haki za kijamii, yanafafanua changamoto za muziki huu katika kuwasilisha haki za kijamii na kutoa mapendekezo kwa makundi ...

  11. NaI(Tl) electron energy resolution

    CERN Document Server

    Mengesha, W

    2002-01-01

    NaI(Tl) electron energy resolution eta sub e was measured using the Modified Compton Coincidence Technique (MCCT). The MCCT allowed detection of nearly monoenergetic internal electrons resulting from the scattering of incident 662 keV gamma rays within a primary NaI(Tl) detector. Scattered gamma rays were detected using a secondary HPGe detector in a coincidence mode. Measurements were carried out for electron energies ranging from 16 to 438 keV, by varying the scattering angle. Measured HPGe coincidence spectra were deconvolved to determine the scattered energy spectra from the NaI(Tl) detector. Subsequently, the NaI(Tl) electron energy spectra were determined by subtracting the energy of scattered spectra from the incident source energy (662 keV). Using chi-squared minimization, iterative deconvolution of the internal electron energy spectra from the measured NaI(Tl) spectra was then used to determine eta sub e at the electron energy of interest. eta sub e values determined using this technique represent va...

  12. Anion-coupled Na efflux mediated by the human red blood cell Na/K pump

    International Nuclear Information System (INIS)

    Dissing, S.; Hoffman, J.F.

    1990-01-01

    The red cell Na/K pump is known to continue to extrude Na when both Na and K are removed from the external medium. Because this ouabain-sensitive flux occurs in the absence of an exchangeable cation, it is referred to as uncoupled Na efflux. This flux is also known to be inhibited by 5 mM Nao but to a lesser extent than that inhibitable by ouabain. Uncoupled Na efflux via the Na/K pump therefore can be divided into a Nao-sensitive and Nao-insensitive component. We used DIDS-treated, SO4-equilibrated human red blood cells suspended in HEPES-buffered (pHo 7.4) MgSO4 or (Tris)2SO4, in which we measured 22Na efflux, 35SO4 efflux, and changes in the membrane potential with the fluorescent dye, diS-C3 (5). A principal finding is that uncoupled Na efflux occurs electroneurally, in contrast to the pump's normal electrogenic operation when exchanging Nai for Ko. This electroneutral uncoupled efflux of Na was found to be balanced by an efflux of cellular anions. (We were unable to detect any ouabain-sensitive uptake of protons, measured in an unbuffered medium at pH 7.4 with a Radiometer pH-STAT.) The Nao-sensitive efflux of Nai was found to be 1.95 +/- 0.10 times the Nao-sensitive efflux of (SO4)i, indicating that the stoichiometry of this cotransport is two Na+ per SO4=, accounting for 60-80% of the electroneutral Na efflux. The remainder portion, that is, the ouabain-sensitive Nao-insensitive component, has been identified as PO4-coupled Na transport and is the subject of a separate paper. That uncoupled Na efflux occurs as a cotransport with anions is supported by the result, obtained with resealed ghosts, that when internal and external SO4 was substituted by the impermeant anion, tartrate i,o, the efflux of Na was inhibited 60-80%. This inhibition could be relieved by the inclusion, before DIDS treatment, of 5 mM Cli,o

  13. Na/K pump inactivation, subsarcolemmal Na measurements, and cytoplasmic ion turnover kinetics contradict restricted Na spaces in murine cardiac myocytes.

    Science.gov (United States)

    Lu, Fang-Min; Hilgemann, Donald W

    2017-07-03

    Decades ago, it was proposed that Na transport in cardiac myocytes is modulated by large changes in cytoplasmic Na concentration within restricted subsarcolemmal spaces. Here, we probe this hypothesis for Na/K pumps by generating constitutive transsarcolemmal Na flux with the Na channel opener veratridine in whole-cell patch-clamp recordings. Using 25 mM Na in the patch pipette, pump currents decay strongly during continuous activation by extracellular K (τ, ∼2 s). In contradiction to depletion hypotheses, the decay becomes stronger when pump currents are decreased by hyperpolarization. Na channel currents are nearly unchanged by pump activity in these conditions, and conversely, continuous Na currents up to 0.5 nA in magnitude have negligible effects on pump currents. These outcomes are even more pronounced using 50 mM Li as a cytoplasmic Na congener. Thus, the Na/K pump current decay reflects mostly an inactivation mechanism that immobilizes Na/K pump charge movements, not cytoplasmic Na depletion. When channel currents are increased beyond 1 nA, models with unrestricted subsarcolemmal diffusion accurately predict current decay (τ ∼15 s) and reversal potential shifts observed for Na, Li, and K currents through Na channels opened by veratridine, as well as for Na, K, Cs, Li, and Cl currents recorded in nystatin-permeabilized myocytes. Ion concentrations in the pipette tip (i.e., access conductance) track without appreciable delay the current changes caused by sarcolemmal ion flux. Importantly, cytoplasmic mixing volumes, calculated from current decay kinetics, increase and decrease as expected with osmolarity changes (τ >30 s). Na/K pump current run-down over 20 min reflects a failure of pumps to recover from inactivation. Simulations reveal that pump inactivation coupled with Na-activated recovery enhances the rapidity and effectivity of Na homeostasis in cardiac myocytes. In conclusion, an autoregulatory mechanism enhances cardiac Na/K pump activity when

  14. Muscle K+, Na+, and Cl- disturbances and Na+-K+ pump inactivation: implications for fatigue

    DEFF Research Database (Denmark)

    McKenna, Michael J; Bangsbo, Jens; Renaud, Jean-Marc

    2008-01-01

    (+)-ATPase activity during exercise stabilizes Na(+) and K(+) concentration gradients and membrane excitability and thus protects against fatigue. However, during intense contraction some Na(+)-K(+) pumps are inactivated and together with further ionic disturbances, likely precipitate muscle fatigue.......Membrane excitability is a critical regulatory step in skeletal muscle contraction and is modulated by local ionic concentrations, conductances, ion transporter activities, temperature, and humoral factors. Intense fatiguing contractions induce cellular K(+) efflux and Na(+) and Cl(-) influx......, causing pronounced perturbations in extracellular (interstitial) and intracellular K(+) and Na(+) concentrations. Muscle interstitial K(+) concentration may increase 1- to 2-fold to 11-13 mM and intracellular K(+) concentration fall by 1.3- to 1.7-fold; interstitial Na(+) concentration may decline by 10 m...

  15. Metallic Na formation in NaCl crystals with irradiation of electron or vacuum ultraviolet photon

    Energy Technology Data Exchange (ETDEWEB)

    Owaki, Shigehiro [Osaka Prefecture Univ., Sakai, Osaka (Japan). Coll. of Integrated Arts and Sciences; Koyama, Shigeko; Takahashi, Masao; Kamada, Masao; Suzuki, Ryouichi

    1997-03-01

    Metallic Na was formed in NaCl single crystals with irradiation of a variety of radiation sources and analyzed the physical states with several methods. In the case of irradiation of 21 MeV electron pulses to the crystal blocks, the optical absorption and lifetime measurement of positron annihilation indicated appearance of Na clusters inside. Radiation effects of electron beam of 30 keV to the crystals in vacuum showed the appearance of not only metallic Na but atomic one during irradiation with Auger electron spectroscopy. Intense photon fluxes in vacuum ultraviolet region of synchrotron radiation were used as another source and an analyzing method of ultraviolet photoelectron spectroscopy. The results showed the metallic Na layered so thick that bulk plasmon can exist. (author)

  16. Hydrolysis of Rice Straw Pretreated by Na2SO3 Over Fe-resin/NaCl

    Directory of Open Access Journals (Sweden)

    YANG Hui

    2017-05-01

    Full Text Available To increase the conversion of rice straw(RS and the yield of products, we employed three methods, which were ultrasonic wave, steam explosion and Na2SO3 pretreatment to pretreat RS(the treated RS noted as CS-RS, ZQ-RS and Na2SO3-RS, respectively and found that Na2SO3 treatment was the best pretreatment method based on XRD, SEM, elemental analysis and content of cellulose, hemicellulose and lignin. The conversion of Na2SO3-RS and the yield of total reducing sugar(TRS and levulinic acid(LA were 97.3%, 29.6% and 13.5%, respectively by 10% Fe-resin in 3.3% NaCl solution under 200 ℃.

  17. Na-ion dynamics in Quasi-1D compound NaV2O4

    International Nuclear Information System (INIS)

    Månsson, M; Umegaki, I; Nozaki, H; Higuchi, Y; Sugiyama, J; Kawasaki, I; Watanabe, I; Sakurai, H

    2014-01-01

    We have used the pulsed muon source at ISIS to study high-temperature Na-ion dynamics in the quasi-one-dimensional (Q1D) metallic antiferromagnet NaV 2 O 4 . By performing systematic zero-field and longitudinal-field measurements as a function of temperature we clearly distinguish that the hopping rate increases exponentially above T diff ≈ 250 K. The data is well fitted to an Arrhenius type equation typical for a diffusion process, showing that the Na-ions starts to be mobile above T diff . Such results make this compound very interesting for the tuning of Q1D magnetism using atomic-scale ion-texturing through the periodic potential from ordered Na-vacancies. Further, it also opens the door to possible use of NaV 2 O 4 and related compounds in energy related applications

  18. Summer sudden Na number density enhancements measured with the ALOMAR Weber Na Lidar

    Directory of Open Access Journals (Sweden)

    D. Heinrich

    2008-05-01

    Full Text Available We present summer Na-densities and atmospheric temperatures measured 80 to 110 km above the Arctic Lidar Observatory for Middle Atmosphere Research (ALOMAR. The Weber Na Lidar is part of ALOMAR, located at 69° N in Norway, 150 km north of the Arctic Circle. The sun does not set here during the summer months, and measurements require a narrowband Faraday Anomalous Dispersion Optical Filter (FADOF.

    We discuss an observed sudden enhancement in the Na number density around 22:00 UT on 1 to 2 June 2006. We compare this observation with previous summer measurements and find a frequent appearance of Na number density enhancements near local midnight. We describe the time of appearance, the altitude distribution, the duration and the strength of these enhancements and compare them to winter observations. We investigate possible formation mechanisms and, as others before, we find a strong link between these Na number density enhancements and sporadic E layers.

  19. Summer sudden Na number density enhancements measured with the ALOMAR Weber Na Lidar

    Directory of Open Access Journals (Sweden)

    D. Heinrich

    2008-05-01

    Full Text Available We present summer Na-densities and atmospheric temperatures measured 80 to 110 km above the Arctic Lidar Observatory for Middle Atmosphere Research (ALOMAR. The Weber Na Lidar is part of ALOMAR, located at 69° N in Norway, 150 km north of the Arctic Circle. The sun does not set here during the summer months, and measurements require a narrowband Faraday Anomalous Dispersion Optical Filter (FADOF. We discuss an observed sudden enhancement in the Na number density around 22:00 UT on 1 to 2 June 2006. We compare this observation with previous summer measurements and find a frequent appearance of Na number density enhancements near local midnight. We describe the time of appearance, the altitude distribution, the duration and the strength of these enhancements and compare them to winter observations. We investigate possible formation mechanisms and, as others before, we find a strong link between these Na number density enhancements and sporadic E layers.

  20. Structure-function relationships of Na+, K+, ATP, or Mg2+ binding and energy transduction in Na,K-ATPase

    DEFF Research Database (Denmark)

    Jorgensen, Peter L.; Pedersen, Per Amstrup

    2000-01-01

    Na,K-ATPase; Mutagenesis; Na+ binding; K+ binding; Tl+ binding; Mg2+ binding; ATP binding; Cation binding site; Energy transduction......Na,K-ATPase; Mutagenesis; Na+ binding; K+ binding; Tl+ binding; Mg2+ binding; ATP binding; Cation binding site; Energy transduction...

  1. Na2SO4-based solid electrolytes for SOx sensors

    DEFF Research Database (Denmark)

    Rao, N.; Schoonman, J.; Toft Sørensen, O.

    1992-01-01

    on the phases present and the structure of the specimens. From a point of view of practical application as SOx sensor material, the Na2SO4 + 5 mol% Y2(SO4)3 + Na2WO4 and Na2SO4+ 4 mol% La2(SO4)3 + Na2WO4 materials are better than undoped Na2SO4 because of their higher conductivity, and absence of a phase...

  2. Long-Range Effects of Na(+) Binding in Na,K-ATPase Reported by ATP.

    Science.gov (United States)

    Middleton, David A; Fedosova, Natalya U; Esmann, Mikael

    2015-12-01

    This paper addresses the question of long-range interactions between the intramembranous cation binding sites and the cytoplasmic nucleotide binding site of the ubiquitous ion-transporting Na,K-ATPase using (13)C cross-polarization magic-angle spinning (CP-MAS) solid-state nuclear magnetic resonance. High-affinity ATP binding is induced by the presence of Na(+) as well as of Na-like substances such as Tris(+), and these ions are equally efficient promoters of nucleotide binding. CP-MAS analysis of bound ATP with Na,K-ATPase purified from pig kidney membranes reveals subtle differences in the nucleotide interactions within the nucleotide site depending on whether Na(+) or Tris(+) is used to induce binding. Differences in chemical shifts for ATP atoms C1' and C5' observed in the presence of Na(+) or Tris(+) suggest alterations in the residues surrounding the bound nucleotide, hydrogen bonding, and/or conformation of the ribose ring. This is taken as evidence of a long-distance communication between the Na(+)-filled ion sites in the membrane interior and the nucleotide binding site in the cytoplasmic domain and reflects the first conformational change ultimately leading to phosphorylation of the enzyme. Stopped-flow fluorescence measurements with the nucleotide analogue eosin show that the dissociation rate constant for eosin is larger in Tris(+) than in Na(+), giving kinetic evidence of the difference in structural effects of Na(+) and Tris(+). According to the recent crystal structure of the E1·AlF4(-)·ADP·3Na(+) form, the coupling between the ion binding sites and the nucleotide side is mediated by, among others, the M5 helix.

  3. Tecnologia simplificada na enfermagem materno infantil

    Directory of Open Access Journals (Sweden)

    Selma Campestrini

    1991-09-01

    Full Text Available A autora apresenta três modelos de tecnologia simplificada da enfermagem materno infantil: o equipamento didático SEIO COBAIA para treinar exercícios e massagens da mama e mamilo; a peça indumentária SUPRETRAUMA - sutiã preventivo de traumatismo mamilar - usado por gestantes; e, a técnica para reverter mamilo umbilicado durante o puerperio imediato. Além de corroborar na promoção do aleitamento materno e na prevenção de desmame precoce, demonstra a possibilidade da enfermagem relacionar o saber teórico-científico com o saber tecnico-prático, na saúde da mulher e da criança, com tecnologia adequada às necessidades, à compreensão e ao bem estar da população.

  4. Eletrencefalograma na síndrome parkinsoniana

    Directory of Open Access Journals (Sweden)

    José Geraldo Camargo Lima

    1973-09-01

    Full Text Available Foram estudados os eletrencefalogramas de 50 pacientes parkinsonianos livres de qualquer antecedente convulsivo, sendo registrados traçados anormais em 40% dos casos. A incidência de traçados anormais foi maior na síndrome parkinsoniana bilateral do que na unilateral (52% e 25%, respectivamente. Entre as anormalidades assinaladas foram as paroxísticas as mais freqüentes (65% dos casos, caracterizando-se predominantemente por surtos de ondas teta. O registro de anormalidades paroxísticas do tipo irritativo encontrado em três casos é salientado. Alterações da atividade de base foram assinaladas em 35% dos pacientes. A idade dos pacientes não parece ter tido importante papel na gênese das anormalidades eletrencefalográficas.

  5. GLOBAL COMMODITY CHAINS NA PERSPECTIVA DE MARKETING

    Directory of Open Access Journals (Sweden)

    Flávio Régio Brambilla

    2014-01-01

    Full Text Available O presente estudo visa a estabelecer uma relação entre as estratégias de canais globais com aspectos do marketing, como a força da marca. Trata-se de conciliar atributos de Estratégia e Marketing. As mudanças econômicas globais levaram a transformações na competição das empresas, obrigando-as a ingressar numa discussão aprimorada acerca das estratégias e competências. Com base na ideia da detenção do conhecimento e das habilidades como verdadeiros diferenciais competitivos, muitos players passam a atuar na gestão do design e da marca como elementos centrais das políticas de negócios, onde a proposição de valor pode ser mais bem definida aos mercados consumidores.

  6. Recent results from NA61/SHINE

    CERN Document Server

    Puławski, Szymon

    2015-01-01

    The main physics goals of the NA61/SHINE programme on strong interactions are the study of the properties of the onset of deconfinement and the search for signatures of the critical point of strongly interacting matter. These goals are pursued by performing an energy (beam momentum 13A -158A GeV/c) and system size (p+p, p+Pb, Be+Be, Ar+Sc, Xe+La) scan. This publication reviews results and plans of NA61/SHINE. In particular, recent inclusive spectra and new results on fluctuations and correlations of identified hadrons in inelastic p+p and centrality selected Be+Be interactions at the SPS energies are presented. The energy dependence of quantities inspired by the Statistical Model of the Early Stage (kink, horn and step) show unexpected behavior in p+p collisions. The NA61/SHINE results are compared with the corresponding data of other experiments and model predictions.

  7. Recent results from NA61/SHINE

    CERN Document Server

    Kowalski, Seweryn

    2015-01-01

    The aim of the NA61/SHINE ion programme is to explore the QCD phase diagram within the range of thermodynamical variables accessible by the SPS. Moreover the experiment provides precision hadron production measurements to improve computation of neutrino fluxes in neutrino oscillation experiments and for improving air shower simulations of cosmic-ray experiments. The main physics goals of the NA61/SHINE ion programme are the study of the properties of the onset of deconfinement and the search for signatures of the critical point of strongly interacting matter. These goals are pursued by performing an energy (beam momentum 13A – 158 A GeV/c) and system size (p+p, p+Pb, Be+Be, Ar+Sc, Xe+La) scan. This paper reviews the status and results of the NA61/SHINE experiment.

  8. A Study of the Distribution of Sodium Cations in the Zeolites NaX, NaY and ZnNaY Using Carbon Monoxide Adsorption and 23Na NMR Techniques

    Science.gov (United States)

    Seidel, A.; Boddenberg, B.

    1995-03-01

    The zeolites NaX, NaY, Zn(55)NaY, and Zn(74)NaY were investigated by means of carbon monoxide adsorption and with static and magic angle spinning (MAS) 23Na NMR spectroscopy. The Na+ distribution between the sodalite (ß)- and supercages of the fully hydrated zeolites NaX and NaY were found to agree with XRD results. In the hydrated zinc-exchanged zeolites the Na+ ions almost exclusively populate the ß-cages. The adsorption isotherms of CO in the dehydrated zeolites were analyzed quantitatively to yield the concentrations of Na+ residing in the supercages. The measured static and MAS 23Na NMR spectra were analyzed by comparing their widths and shapes with simulated central transition patterns and yield, inter alia, the concentrations of Na+ associated with the spectrum components. Arguments are put forward that 23Na NMR of dehydrated zeolites is well suited to distinguish Na+ cations in highly symmetric environments and mobile Na+ species from others located on general positions, but further resolution is hardly feasible.

  9. Crystal structure of a Na+-bound Na+,K+-ATPase preceding the E1P state.

    Science.gov (United States)

    Kanai, Ryuta; Ogawa, Haruo; Vilsen, Bente; Cornelius, Flemming; Toyoshima, Chikashi

    2013-10-10

    Na(+),K(+)-ATPase pumps three Na(+) ions out of cells in exchange for two K(+) taken up from the extracellular medium per ATP molecule hydrolysed, thereby establishing Na(+) and K(+) gradients across the membrane in all animal cells. These ion gradients are used in many fundamental processes, notably excitation of nerve cells. Here we describe 2.8 Å-resolution crystal structures of this ATPase from pig kidney with bound Na(+), ADP and aluminium fluoride, a stable phosphate analogue, with and without oligomycin that promotes Na(+) occlusion. These crystal structures represent a transition state preceding the phosphorylated intermediate (E1P) in which three Na(+) ions are occluded. Details of the Na(+)-binding sites show how this ATPase functions as a Na(+)-specific pump, rejecting K(+) and Ca(2+), even though its affinity for Na(+) is low (millimolar dissociation constant). A mechanism for sequential, cooperative Na(+) binding can now be formulated in atomic detail.

  10. MANAGEMENT DOGODKOV NA PRIMERU NIKE KONVENCIJE

    OpenAIRE

    Kapić, Sara

    2010-01-01

    V diplomski nalogi je predstavljen potek ustvarjanja in izvedbe dogodka, ki zajema številne aktivnosti, in sicer na primeru Nike konvencije. Namen diplomske naloge je namreč podati kritično oceno izvajanja aktivnosti, z namenom ugotoviti, katere aktivnosti bi se v okviru upravljanja z dogodkom lahko izpeljale boljše in podati predloge za uspešnejšo zasnovo in organizacijo naslednje Nike konvencije. Na podlagi posnetka je ugotovljeno, da je pri organizaciji, vodenju, izvedbi in nadzoru prihaja...

  11. A Imagem como Ruína

    Directory of Open Access Journals (Sweden)

    Míriam Volpe

    2001-12-01

    Full Text Available O dialogismo ente o filme Citizen Kane, de Orson Welles, e o poema “Kubla Khan”, de S.T. Coleridgé, é analisado, sendo evidenciados não só o tema em comum – o mito do Paraíso perdido – como também a similariedade na organização do disurso na justaposição das images, como fragmentos da memória a serem preservados.

  12. Recent results and prospects from NA62

    Directory of Open Access Journals (Sweden)

    Bizzeti Andrea

    2016-01-01

    K+ → π+ vv̄ is a theoretically very clean decay where indirect effects of new physics may be detectable. The NA62 apparatus has been significantly upgraded between 2008 and 2014 in order to measure the branching ratio of this decay with 10% precision. The NA62 experiment took data with the new setup in pilot runs in 2014 and 2015, reaching the design beam intensity. Results of first data quality studies in view of the 2016-2017 physics runs are presented.

  13. Prenova razsvetljave na Fakulteti za elektrotehniko

    OpenAIRE

    ŠTAJDOHAR, JAN

    2015-01-01

    Pri energetskem pregledu stavbe Fakultete za elektrotehniko v Ljubljani je bilo ugotovljeno, da je razsvetljava prostorov na fakulteti v veliko primerih stara, neprimerna in energetsko potratna. V diplomski nalogi smo se posvetili energetski analizi prenove razsvetljave predavalnice P7 in kabineta AZ101. Pri načrtovanju in izbiri svetil smo upoštevali vse tehnične in energetske smernice za učinkovito razsvetljavo prostorov za izobraževanje. V uvodu smo opisali fizikalne osnove svetlobe, k...

  14. Osteossarcoma parosteal: aspectos na radiologia convencional

    OpenAIRE

    Nanci Neto,Francisco; Marchiori,Edson; Vianna,Alberto Domingues; Aymoré,Ierecê Lins; Almeida,Ana Luiza Brito de; Irion,Klaus L.; Collares,Felipe Birchal

    2007-01-01

    OBJETIVO: Avaliar os achados clínicos mais importantes do osteossarcoma parosteal e descrever os seus aspectos mais comuns na radiologia convencional. MATERIAIS E MÉTODOS: Estudo retrospectivo com 26 pacientes com osteossarcoma parosteal, provenientes do arquivo do Clube do Osso, Rio de Janeiro, RJ, e análise dos principais achados clínicos e aspectos radiológicos. RESULTADOS: A doença predominou em pacientes do sexo feminino e teve idade média de acometimento na terceira década de vida. Os a...

  15. Lamiaceae na Serra Negra, Minas Gerais, Brasil

    OpenAIRE

    Mota, Michelle Christine de Almeida; Pastore, José Floriano Barêa; Marques Neto, Roberto; Harley, Raymond Mervyn; Salimena, Fátima Regina

    2017-01-01

    Resumo A Serra Negra está inserida na área do Complexo da Serra da Mantiqueira, no domínio da Mata Atlântica, com altitudes entre 800 e 1.650 m, com vegetação em mosaico representada, entre outros, por campos rupestres em afloramentos quartzíticos e floresta nebulares. A família Lamiaceae (Labiatae) está representada na Serra Negra por 10 gêneros e 17 espécies: Aegiphila integrifolia, Cantinoa carpinifolia, C. macrotera, C. muricata, Eriope macrostachya, Hoehnea scutellarioides, Hyptidendron ...

  16. VARNOSTNA POLITIKA NA PODROČJU INFORMATIKE

    OpenAIRE

    Šavor, Gašper

    2011-01-01

    Informacijska tehnologija postaja vse bolj pomemben del poslovanja vsakega podjetja ter ţivljenja vsakega posameznika. Zato je v interesu vseh, da so ključne informacije dobro zaščitene. V prvem delu diplomske naloge smo predstavili informacijske sisteme, njihovo delitev ter vrste. Prav tako smo podrobneje predstavili ţivljenjski cikel ter 4-stopenjski model razvoja informacijskega sistema. V osrednjem delu naloge smo se osredotočili na nevarnosti na področju informatike ter vrste zašči...

  17. ARTE E TRANSGRESSÃO NA MODERNIDADE

    OpenAIRE

    Cascelli Farinasso, Gabriela

    2014-01-01

    O presente artigo busca explorar a arte como ferramenta para mudanças sociais na modernidade relacionando-a com os conceitos apresentados por Nicolas Bourriaud em seu livro Estética Relacional. A Street Art é apresentada como recorte dentre os movimentos artísticos, ressaltando-se sua importância e suas características do ponto de vista espacial e temporal e na criação de “lugares de pausa” no meio urbano, que levam o observador a refletir sobre a obra e o desviam do seu percurso. A transgres...

  18. O passado presente na literatura angolana

    Directory of Open Access Journals (Sweden)

    Rita Chaves

    2000-03-01

    Full Text Available A poderosa presença da História na configuração do projeto literário angolano assegura ao passado um lugar de destaque. Como matriz de significados no processo de construção da identidade cultural de uma sociedade em manifesto movimento, o passado ganha formas e sentidos múltiplos que interferem na leitura do presente e nas projeções do futuro realizadas pelos escritores angolanos, do período colonialaos nossos dias.

  19. Controlo de qualidade na empresa Valvie

    OpenAIRE

    Agrela, Sandra da Conceição Rodrigues

    2015-01-01

    Dissertação apresentada à Escola Superior Agrária do Instituto Politécnico de Castelo Branco para cumprimento dos requisitos necessários à obtenção do grau de Mestre em Inovação e Qualidade na Produção Alimentar. A qualidade está presente na realidade das indústrias atualmente mais do que nunca. Partindo do princípio de que qualidade seja atender e superar a expetativa do consumidor, a empresa que apresentar melhor performance nesse quesito será a de maior sucesso no mercado...

  20. O sentimento de respeito na moral kantiana

    OpenAIRE

    Stadnick, Maria Margareth

    2007-01-01

    Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Filosofia e Ciências Humanas. Programa de Pós-Graduação em Filosofia. A presente pesquisa tem como proposta fundamental a investigação do sentimento de respeito na moral kantiana. Neste sentido, nos detemos a investigar sua relação com a proposta moral de Kant, assim como verificarmos o lugar sistemático que ocupa o sentimento de respeito na moral kantiana. Dentro desse espírito, buscamos reconstruir a estrutura arg...

  1. Status for 2017, CERN NA63

    CERN Document Server

    Uggerhoej, UI

    2017-01-01

    In the NA63 experiment of May-June 2017 the purpose was to look for the effect of classical radiation reaction as described in \\cite{DiPiazza20171} but for 50 GeV positrons aligned to the (110) plane of silicon crystals of varying thicknesses in the range 1-6 mm. The data which was taken during the run shows promising results, but the final verdict awaits accurate calculations of the theoretically expected spectra, and a final analysis. For the 2016 results on quantum radiation reaction obtained by CERN NA63, we have submitted a manuscript, which is presently under refereeing \\cite{Wist17}.

  2. O problema do conhecimento verdadeiro na epidemiologia

    Directory of Open Access Journals (Sweden)

    Ayres José Ricardo de Carvalho Mesquita

    1992-01-01

    Full Text Available São examinadas as bases filosóficas da validação do conhecimento científico, com o intuito de estabelecer uma visão crítica a respeito da adoção das proposições de Popper na epidemiologia. Ressalta-se o caráter conservador que resulta das limitações técnicas implicadas na sua adoção, não obstante o evidente aumento da racionalidade e da criatividade heurística que propicia.

  3. Europlanet-2020 NA1 Exchange Program

    Science.gov (United States)

    Genzer, M.; Szego, K.; Haukka, H.; Harri, A.-M.

    2017-09-01

    The task of Exchange Program of NA1 is to support the activities of EPN2020 with experts and scientific exchange whenever it is needed. Short visits (up to 1 week) with the goal of improving infrastructure facilities and services offered to the scientific community are supported from this task. Since the start of the EPN2020 in September 2015 we have received and approved 14 applications for exchange program travel. More general and specifically targeted calls are planned for the future. The calls are announced on Europlanet-2020 NA1 web site.

  4. Abordagem neurologica na sindrome do X fragil

    OpenAIRE

    Marilisa Mantovani Guerreiro

    1993-01-01

    Resumo: Com o propósito de realizar a abordagem neurológica na Síndrome do X Frágil (SXF), estudaram-se 11 pacientes com este diagnóstico citogenético. A idade variou de 8 a 19 anos. Nove pacientes eram do sexo masculino e dois do feminino. Todos os indivíduos apresentaram pavilhões auriculares grandes e faces alongadas. Observou-se fronte proeminente em 63% dos casos e macrorquidia em 33% dentre aqueles do sexo masculino. Atraso na aquisição da fala, fala repetitiva, perseverativa, impulsiva...

  5. Na+/K+-ATPase: Activity and inhibition

    Science.gov (United States)

    Čolović, M.; Krstić, D.; Krinulović, K.; Momić, T.; Savić, J.; Vujačić, A.; Vasić, V.

    2009-09-01

    The aim of the study was to give an overview of the mechanism of inhibition of Na+/K+-ATPase activity induced by some specific and non specific inhibitors. For this purpose, the effects of some ouabain like compounds (digoxin, gitoxin), noble metals complexes ([PtCl2DMSO2], [AuCl4]-, [PdCl4]2-, [PdCl(dien)]+, [PdCl(Me4dien)]+), transition metal ions (Cu2+, Zn2+, Fe2+, Co2+), and heavy metal ions (Hg2+, Pb2+, Cd2+) on the activity of Na+/K+-ATPase from rat synaptic plasma membranes (SPM), porcine cerebral cortex and human erythrocytes were discussed.

  6. Na, K-ATPase as signaling transducer

    OpenAIRE

    Li, Juan

    2007-01-01

    It is now generally agreed that Na,K-ATPase (NKA), in addition to its role in the maintenance of Na+ and K+ gradients across the cell membrane, is a signal transducer. Our group has identified a novel signaling pathway where NKA interact with IP3R to form a signaling microdomain. Ouabain, a specific ligand of NKA, activates this pathway, triggers slow Ca2+ oscillations and activates NF-κB. In current study, the molecular mechanisms and some important downstream effects of NK...

  7. Glutathionylation-Dependence of Na(+)-K(+)-Pump Currents Can Mimic Reduced Subsarcolemmal Na(+) Diffusion.

    Science.gov (United States)

    Garcia, Alvaro; Liu, Chia-Chi; Cornelius, Flemming; Clarke, Ronald J; Rasmussen, Helge H

    2016-03-08

    The existence of a subsarcolemmal space with restricted diffusion for Na(+) in cardiac myocytes has been inferred from a transient peak electrogenic Na(+)-K(+) pump current beyond steady state on reexposure of myocytes to K(+) after a period of exposure to K(+)-free extracellular solution. The transient peak current is attributed to enhanced electrogenic pumping of Na(+) that accumulated in the diffusion-restricted space during pump inhibition in K(+)-free extracellular solution. However, there are no known physical barriers that account for such restricted Na(+) diffusion, and we examined if changes of activity of the Na(+)-K(+) pump itself cause the transient peak current. Reexposure to K(+) reproduced a transient current beyond steady state in voltage-clamped ventricular myocytes as reported by others. Persistence of it when the Na(+) concentration in patch pipette solutions perfusing the intracellular compartment was high and elimination of it with K(+)-free pipette solution could not be reconciled with restricted subsarcolemmal Na(+) diffusion. The pattern of the transient current early after pump activation was dependent on transmembrane Na(+)- and K(+) concentration gradients suggesting the currents were related to the conformational poise imposed on the pump. We examined if the currents might be accounted for by changes in glutathionylation of the β1 Na(+)-K(+) pump subunit, a reversible oxidative modification that inhibits the pump. Susceptibility of the β1 subunit to glutathionylation depends on the conformational poise of the Na(+)-K(+) pump, and glutathionylation with the pump stabilized in conformations equivalent to those expected to be imposed on voltage-clamped myocytes supported this hypothesis. So did elimination of the transient K(+)-induced peak Na(+)-K(+) pump current when we included glutaredoxin 1 in patch pipette solutions to reverse glutathionylation. We conclude that transient K(+)-induced peak Na(+)-K(+) pump current reflects the effect

  8. Response of saliva Na/K ratio to changing Na supply of lactating cows under tropical conditions.

    Science.gov (United States)

    Thiangtum, Wandee; Schonewille, J Thomas; Verstegen, Martin Wa; Arsawakulsudhi, Supot; Rukkwamsuk, Theera; Hendriks, Wouter H

    2017-06-01

    Factorial determination of the sodium (Na) requirement of heat-stressed lactating cows is hindered by accurate estimates of the Na losses through sweat. Direct studies, therefore, may be needed requiring information on the time course of healthy animals to become Na depleted and the subsequent rate of repletion. The rate of Na depletion and subsequent rate of Na repletion with two levels of dietary Na to lactating dairy cows housed under tropical conditions were investigated using the salivary Na/K. The 12 lactating cows (salivary Na/K ratio 14.6) rapidly developed clinical signs of Na deficiency, including pica, polyuria and polydipsia, reduced body weight and reduced milk yield when fed a low-Na ration (0.33 g kg -1 dry matter (DM)) for 3 weeks. Deficiency symptoms were associated with a rapid decrease in salivary Na/K ratio to cows with NaCl to a ration concentration of 1.1 or 1.6 g Na kg -1 DM for 5 weeks did not restore salivary Na/K ratio to values of >6. A daily Na intake of heat-stressed lactating cows to a ration intake of 1.6 g Na kg -1 DM was insufficient to restore Na deficiency. One week was sufficient to deplete heat-stressed lactating cows of Na, allowing for rapid dose-response studies utilizing the salivary Na/K ratio as a parameter for Na status of cows under tropical conditions. © 2016 Society of Chemical Industry. © 2016 Society of Chemical Industry.

  9. Estudo baseado na pesquisa de anticorpos IgM antitripanossoma no soro, destinado a avaliar a transmissão congênita da doença de Chagas, em hospital previdenciário da cidade de São Paulo

    Directory of Open Access Journals (Sweden)

    Vicente Amato Neto

    1977-02-01

    Full Text Available Efetuaram os autores, em hospital previdenciário da cidade de São Pauto, estudo destinado a avaliar, quantitativamente, a ocorrência de transmissão congênita da doença de Chagas. Quatrocentas e noventa e duas mulheres grávidas foram inquiridas sobre a possibilidade de terem, anteriormente, adquirido essa parasitose e, a propósito, ficou apurado que 22 poderiam, com base em dados de diversas ordens, estar infectadas pelo Trypanosoma cruzi Quanto a essas pessoas selecionadas, por ocasião do parto houve coleta de sangue do cordão umbilical, permitindo execução de provas soro lógicas para diagnóstico da protozoose em questão e, fundamentalmente, de pesquisa de anticorpos IgM antitripanossoma por imunofluorescência. Em cinco oportunidades esses testes resultaram positivos, mas nunca houve detecção dos anticorpos do tipo mencionado, demarcando a inexistência, no grupo considerado, de passagens transplancetárias do microorganismo em tela. A investigação levada a efeito não evidenciou, portanto, contaminação de recém-nascido, de origem materna. Entretanto, serve de estímulo para averiguações congêneres em outros ambientes e regiões, nas quais endemicidade da tripanossomíase a nível sócio-econômico afiguram-se diferentes dos em vigor na análise realizada.

  10. A vivência de alunos de graduação em enfermagem na assistência à saúde da mulher em uma comunidade de baixa renda: uma abordagem fenomenológica The background got on assistance to woman health in a low income community by undergraduate students of nursing: A phenomenological approach

    Directory of Open Access Journals (Sweden)

    Miriam Aparecida Barbosa Merighi

    1998-08-01

    Full Text Available Neste estudo nossa trajetória dirigiu-se para a compreensão da experiência vivida pelos alunos do Curso de Graduação em Enfermagem, da EEUSP, na assistência à mulher em uma comunidade de baixa renda da cidade de São Paulo. Obtivemos descrições dos alunos e os dados foram analisados seguindo os passos da fenomenologia. Identificamos cinco temas: experiência gratificante, estimulante e valiosa; experiência de vida, de crescimento pessoal e de quebra de preconceito; atividade que permite conhecer o outro lado da assistência; atividade prática que possibilita sedimentação do conhecimento adquirido teoricamente; experiência importante e necessária. A experiência vivenciada pelos alunos mostrou-se satisfatória favorecendo o processo de ensino-aprendizagem.Our trajectory in this study has addressed to the comprehension of experience which undergraduate students in the Nursing School of USP. This work has been developed in a low incomme community of São Paulo city. We've got descriptions of the students and the data were discussed following the steps of phenomenological assay. We've identified five themes: rewarding experience, stimulant and necessary; experience of life, personal growth and disrupting with prejudice; activity which permits to know the other side of assistance; important and valuable experience; practice activity which makes possible the acquired know edge sedimentation theoretically. The graduation students experience was satisfactory and it was favorable to the teaching-learning process.

  11. Water transport by the renal Na(+)-dicarboxylate cotransporter

    DEFF Research Database (Denmark)

    Meinild, A K; Loo, D D; Pajor, A M

    2000-01-01

    . This solute-coupled influx of water took place in the absence of, and even against, osmotic gradients. There was a strict stoichiometric relationship between Na(+), substrate, and water transport of 3 Na(+), 1 dicarboxylate, and 176 water molecules/transport cycle. These results indicate that the renal Na......This study investigated the ability of the renal Na(+)-dicarboxylate cotransporter, NaDC-1, to transport water. Rabbit NaDC-1 was expressed in Xenopus laevis oocytes, cotransporter activity was measured as the inward current generated by substrate (citrate or succinate), and water transport...... was monitored by the changes in oocyte volume. In the absence of substrates, oocytes expressing NaDC-1 showed an increase in osmotic water permeability, which was directly correlated with the expression level of NaDC-1. When NaDC-1 was transporting substrates, there was a concomitant increase in oocyte volume...

  12. Presoja notranjih kontrol pri obračunu davka na dodano vrednost na primeru "Podjetja x"

    OpenAIRE

    Majcen, Borut

    2016-01-01

    Poslovanje podjetja si je ob odsotnosti notranjih kontrol nemogoče predstavljati. Podjetja so podvržena raznim tveganjem, še posebej v današnjih razmerah globalnega poslovanja, ko se podjetja soočajo z vedno novimi izzivi, kar prinaša tudi nova tveganja. Najučinkovitejši ukrep za obvladovanje tveganj predstavlja vzpostavitev sistema notranjih kontrol. Obvladovanje tveganj pa ne poteka samo na ravni podjetja kot celote, ampak je prisotno na vseh področjih delovanja podjetja, torej tudi na p...

  13. Intracellular Na(+) and metabolic modulation of Na/K pump and excitability in the rat suprachiasmatic nucleus neurons.

    Science.gov (United States)

    Wang, Yi-Chi; Yang, Jyh-Jeen; Huang, Rong-Chi

    2012-10-01

    Na/K pump activity and metabolic rate are both higher during the day in the suprachiasmatic nucleus (SCN) that houses the circadian clock. Here we investigated the role of intracellular Na(+) and energy metabolism in regulating Na/K pump activity and neuronal excitability. Removal of extracellular K(+) to block the Na/K pump excited SCN neurons to fire at higher rates and return to normal K(+) to reactivate the pump produced rebound hyperpolarization to inhibit firing. In the presence of tetrodotoxin to block the action potentials, both zero K(+)-induced depolarization and rebound hyperpolarization were blocked by the cardiac glycoside strophanthidin. Ratiometric Na(+) imaging with a Na(+)-sensitive fluorescent dye indicated saturating accumulation of intracellular Na(+) in response to pump blockade with zero K(+). The Na(+) ionophore monensin also induced Na(+) loading and hyperpolarized the membrane potential, with the hyperpolarizing effect of monensin abolished in zero Na(+) or by pump blockade. Conversely, Na(+) depletion with Na(+)-free pipette solution depolarized membrane potential but retained residual Na/K pump activity. Cyanide inhibition of oxidative phosphorylation blocked the Na/K pump to depolarize resting potential and increase spontaneous firing in most cells, and to raise intracellular Na(+) levels in all cells. Nonetheless, the Na/K pump was incompletely blocked by cyanide but completely blocked by iodoacetate to inhibit glycolysis, indicating the involvement of both oxidative phosphorylation and glycolysis in fueling the Na/K pump. Together, the results indicate the importance of intracellular Na(+) and energy metabolism in regulating Na/K pump activity as well as neuronal excitability in the SCN neurons.

  14. NA49: lead-lead collision

    CERN Multimedia

    1996-01-01

    This is an image of an actual lead ion collision taken from tracking detectors on the NA49 experiment, part of the heavy ion project at CERN. These collisions produce a very complicated array of hadrons as the heavy ions break up. It is hoped that one of these collisions will eventually create a new state of matter known as quark-gluon plasma.

  15. Leitura na escola: um barco à deriva?

    Directory of Open Access Journals (Sweden)

    Teixeira, Marlene

    2008-01-01

    Full Text Available Este artigo busca, na teoria da enunciação de É. Benveniste, elementos para repensar o trabalho com a leitura na escola. Considera que, na discussão das noções gêmeas de forma e sentido, o autor formula uma concepção de significado que, de um lado, pode deter a interpretação à deriva, implicada na visão de leitura centrada no leitor, e, de outro lado, possibilita que se transcenda a idéia de que é pela decifração mdo código que se dá o processo de construção do significado. Conclui que, no processo de leitura, é sempre de um trabalho com a língua que se trata, trabalho que se renova a cada ato de aproximação do aluno com o texto, porque a língua é submetida ao ato de enunciação

  16. NA48: Wiring up for Change

    CERN Multimedia

    2001-01-01

    The NA48 Collaboration is rebuilding its drift chambers ready for the experiment to start up again this coming July. An intricate task involving the soldering of over 24,000 wires! The future of the NA48 experiment is coming right down to the wire, that is, the wires which the Collaboration is installing in the clean room of Hall 887 on the Prévessin site. Six days a week, technicians are working in shifts to rebuild the experiment's drift chambers. The original chambers were damaged when a section of a vacuum tube imploded at the end of 1999. A year ago, CERN gave the green light for this essential part of the spectrometer to be rebuilt, so the NA48 experiment, which studies CP violation (see box), still has a bright future ahead of it. Three years of data-taking ahead The NA48 experiment aims to penetrate the secrets of CP (Charge Parity) violation. Charge and parity are two parameters which distinguish a particle from an antiparticle. In other words, an electron possesses a negative electric ...

  17. Haalbaarheid voortijdige liberalisering na 1 april 2009

    NARCIS (Netherlands)

    Baarsma, B.

    2009-01-01

    Al geruime tijd worden door de politiek, postbedrijven en vakbonden gesprekken gevoerd over de liberalisering van de postmarkt. In april 2008 is door de sociale partners een beginselakkoord gesloten en november 2008 is een CAO opgesteld. Het is de bedoeling om binnen 3½ jaar na liberalisering ten

  18. Experiment NA57 at the CERN SPS

    Czech Academy of Sciences Publication Activity Database

    Antinori, F.; Balada, A.; Barbera, R.; Píška, Karel; Staroba, Pavel; Závada, Petr

    1999-01-01

    Roč. 25, - (1999), s. 473-479 ISSN 0954-3899 Institutional research plan: CEZ:AV0Z1010920 Keywords : NA57 * production of strange, multistrange particles * baryons, antibaryons * ultrarelativistic nucleus - nucleus collisions * SPS * strangeness enhancement * number of participants Subject RIV: BF - Elementary Particles and High Energy Physics Impact factor: 1.620, year: 1999

  19. Pijn tijdens of na de wortelkanaalbehandeling

    NARCIS (Netherlands)

    Wesselink, P.R.

    2012-01-01

    Een wortelkanaalbehandeling kan pijn veroorzaken tijdens en/of na de behandeling. Tijdens de behandeling moet dan onderscheid worden gemaakt tussen pijn bij een pulpitis en pijn bij een necrotische pulpa. In beide gevallen kan die pijn effectief worden bestreden, afhankelijk van de toestand waarin

  20. Probing luminescence centers in Na rich feldspar

    DEFF Research Database (Denmark)

    Prasad, Amit Kumar; Lapp, Torben; Kook, Myung Ho

    2016-01-01

    our understanding of the luminescence mechanisms and recombination sites, in a sample of Na rich plagioclase feldspar (oligoclase). Both the UV and violet–blue emissions show resonant excitations arising from a distribution of energy levels. We propose, contrary to the general understanding...

  1. Acetylene diffusion in Na-Y zeolite

    Indian Academy of Sciences (India)

    ideal guest molecule to start with. Here we ... In that case the incoherent scattering law, Sinc(Q, ω), alone describes the dynamics. Q(=k−k0) is the .... The results of QENS measurements to study the diffusion of acetylene gas in zeolite. Na-Y at ...

  2. Therapy of hyperthyroidism with Na131I

    International Nuclear Information System (INIS)

    Kakehi, Hirotake; Furukawa, Takashi; Fukakusa, Shunichi; Futonaka, Hiroshi; Takahashi, Yuji

    1984-01-01

    Forty one patients of hyperthyroidism were treated with Na 131 I. Men and women are in the ratio 1:3.1. The ages of patients are between twenties and sixties and the forties are the highest in number. The observation period of clinical courses is between 1 and 8 years. The number of patients observed over 5 years are 51% of them and over 2 years are 83%. The treatment frequency is as follows: On 37 cases each one was treated once with Na 131 I. 2 cases twice, 1 case at 4 times in 3 years and 1 case at 5 times in 6 years. The treatment doses are between 4,000-6,000 rad (40-60 Gray). In the cases treated with the irradiation dose of 6,000 rad, we often saw hypothyroidism. In cases aiming 4,000-5,000 rad, there is a tendency of leaving hyperthyroidism unrecovered. In conclusion, the patients should be treated giving 4,000-5,000 rad or with Na 131 I doses of 3-6mCi. If the effects of the treatment are insufficient, the patients should be further treated with anti-thyroid drug or treated again with Na 131 I. As the result, there are at present 25 cases (61.0%) in normal status of the thyroid gland, 12 cases (29.2%) in hyperthyroidism and 4 cases (9.8%) in hypothyroidism totaling 41 cases in all. (author)

  3. Nucleotide binding to Na+/K+-ATPase

    Czech Academy of Sciences Publication Activity Database

    Kubala, Martin; Lánský, Zdeněk; Ettrich, R.; Plášek, J.; Teisinger, Jan; Amler, Evžen

    2005-01-01

    Roč. 272, č. S1 (2005), s. 191-191 E-ISSN 1742-4658. [FEBS Congress /30./ and IUBMB Conference /9./. 02.07.2005-07.07.2005, Budapest] Keywords : Na+/K+- ATPase * ATP binding * TNP-ATP Subject RIV: BO - Biophysics

  4. Concentratie gewasbeschermingsmiddelen na verhitting dompelbad bloembollen

    NARCIS (Netherlands)

    Bulle, A.A.E.; Lans, van der A.M.; Aanholt, van J.T.M.

    2014-01-01

    De meest gebruikte methode van ontsmetting van bloembollen en –knollen is een dompeling in een mix van fungiciden. In het proces van bolontsmetting worden partijen bollen na elkaar ontsmet in hetzelfde dompelbad. Met een partij bollen kan een dompelbad behoorlijk vervuild raken met bijvoorbeeld

  5. Laser trapping of 21Na atoms

    International Nuclear Information System (INIS)

    Lu, Zheng-Tian.

    1994-09-01

    This thesis describes an experiment in which about four thousand radioactive 21 Na (t l/2 = 22 sec) atoms were trapped in a magneto-optical trap with laser beams. Trapped 21 Na atoms can be used as a beta source in a precision measurement of the beta-asymmetry parameter of the decay of 21 Na → 21 Ne + Β + + v e , which is a promising way to search for an anomalous right-handed current coupling in charged weak interactions. Although the number o trapped atoms that we have achieved is still about two orders of magnitude lower than what is needed to conduct a measurement of the beta-asymmetry parameter at 1% of precision level, the result of this experiment proved the feasibility of trapping short-lived radioactive atoms. In this experiment, 21 Na atoms were produced by bombarding 24 Mg with protons of 25 MeV at the 88 in. Cyclotron of Lawrence Berkeley Laboratory. A few recently developed techniques of laser manipulation of neutral atoms were applied in this experiment. The 21 Na atoms emerging from a heated oven were first transversely cooled. As a result, the on-axis atomic beam intensity was increased by a factor of 16. The atoms in the beam were then slowed down from thermal speed by applying Zeeman-tuned slowing technique, and subsequently loaded into a magneto-optical trap at the end of the slowing path. The last two chapters of this thesis present two studies on the magneto-optical trap of sodium atoms. In particular, the mechanisms of magneto-optical traps at various laser frequencies and the collisional loss mechanisms of these traps were examined

  6. Učinak video igre "Flappy Bird" na adolescente

    OpenAIRE

    Horvat, Marija

    2018-01-01

    Ovaj diplomski rad nastoji predstaviti uvid u učinke videoigre Flappy Bird na adolescente, fokusirajući se pritom na to potiče li ona nasilno ponašanje te nastoji odgovoriti na pitanje koliko je ta videoigra bila popularna među adolescentima u Hrvatskoj te po čemu je smatraju posebnom, tj. specifičnom. U tu svrhu provedeno je anketno istraživanje, a isti anketni upitnik proveden je na terenu i putem interneta te su uspoređeni rezultati. Anketni upitnik konstruiran je na način da se prvi dio u...

  7. On the Stability of NaO2 in Na-O2 Batteries.

    Science.gov (United States)

    Liu, Chenjuan; Carboni, Marco; Brant, William R; Pan, Ruijun; Hedman, Jonas; Zhu, Jiefang; Gustafsson, Torbjörn; Younesi, Reza

    2018-04-25

    Na-O 2 batteries are regarded as promising candidates for energy storage. They have higher energy efficiency, rate capability, and chemical reversibility than Li-O 2 batteries; in addition, sodium is cheaper and more abundant compared to lithium. However, inconsistent observations and instability of discharge products have inhibited the understanding of the working mechanism of this technology. In this work, we have investigated a number of factors that influence the stability of the discharge products. By means of in operando powder X-ray diffraction study, the influence of oxygen, sodium anode, salt, solvent, and carbon cathode were investigated. The Na metal anode and an ether-based solvent are the main factors that lead to the instability and decomposition of NaO 2 in the cell environment. This fundamental insight brings new information on the working mechanism of Na-O 2 batteries.

  8. Regeneration of plantlets under NaCl stress from NaN3 treated ...

    African Journals Online (AJOL)

    use

    2011-11-16

    Nov 16, 2011 ... plant regeneration under NaCl stressed conditions was assessed in some sugarcane ( ... cell is a useful work for the establishment of pure form of ... balance. The relative water contents (RWC) were calculated .... J. Life Sci.

  9. Equilibrium chemical transformations in NaPO3 + NaCl melts

    International Nuclear Information System (INIS)

    Kovarskaya, E.N.; Rodionov, Yu.I.

    1988-01-01

    Because of the problems of the burial of solidified radioactive wastes into different geological rock formations, in particular into massives of rock-salt, the state of molten polyphosphate-chloride mixtures (taking into account the chemical character of the interaction of their components) for a prolonged period of time. The equilibrium products of the reaction in the NaPO 3 -NaCl system were studied in melts in air in the composition range of 30-70 mole % NaCl. It was shown that with increase in the NaCl content in the mixtures, the polyphosphate gradually depolymerizes to sodium tri-, di-, and monophosphates, and the composition of the equilibrium melts is dependent only on the ratio between the components in the initial molten mixtures. The time until the equilibrium is attained is shorter, the higher is the experimental temperature

  10. Transmural gradients in Na/K pump activity and [Na+]I in canine ventricle.

    Science.gov (United States)

    Gao, J; Wang, W; Cohen, I S; Mathias, R T

    2005-09-01

    There are well-documented differences in ion channel activity and action potential shape between epicardial (EPI), midmyocardial (MID), and endocardial (ENDO) ventricular myocytes. The purpose of this study was to determine if differences exist in Na/K pump activity. The whole cell patch-clamp was used to measure Na/K pump current (I(P)) and inward background Na(+)-current (I(inb)) in cells isolated from canine left ventricle. All currents were normalized to membrane capacitance. I(P) was measured as the current blocked by a saturating concentration of dihydro-ouabain. [Na(+)](i) was measured using SBFI-AM. I(P)(ENDO) (0.34 +/- 0.04 pA/pF, n = 17) was smaller than I(P)(EPI) (0.68 +/- 0.09 pA/pF, n = 38); the ratio was 0.50 with I(P)(MID) being intermediate (0.53 +/- 0.13 pA/pF, n = 19). The dependence of I(P) on [Na(+)](i) or voltage was essentially identical in EPI and ENDO (half-maximal activation at 9-10 mM [Na(+)](i) or approximately -90 mV). Increasing [K(+)](o) from 5.4 to 15 mM caused both I(P)(ENDO) and I(P)(EPI) to increase, but the ratio remained approximately 0.5. I(inb) in EPI and ENDO were nearly identical ( approximately 0.6 pA/pF). Physiological [Na(+)](i) was lower in EPI (7 +/- 2 mM, n = 31) than ENDO (12 +/- 3 mM, n = 29), with MID being intermediate (9 +/- 3 mM, n = 22). When cells were paced at 2 Hz, [Na(+)](i) increased but the differences persisted (ENDO 14 +/- 3 mM, n = 10; EPI 9 +/- 2 mM, n = 10; and MID intermediate, 11 +/- 2 mM, n = 9). Based on these results, the larger I(P) in EPI appears to reflect a higher maximum turnover rate, which implies either a larger number of active pumps or a higher turnover rate per pump protein. The transmural gradient in [Na(+)](i) means physiological I(P) is approximately uniform across the ventricular wall, whereas transporters that utilize the transmembrane electrochemical gradient for Na(+), such as Na/Ca exchange, have a larger driving force in EPI than ENDO.

  11. Isotope separation of 22Na and 24Na with using light induced drift effect

    International Nuclear Information System (INIS)

    Hradecny, C.; Tethal, T.; Ermolaev, I.M.; Zemlyanoj, S.G.; Zuzaan, P.

    1993-01-01

    The LIDIS (Light Drift Isotope Separation) separator without a gas flow is discussed. It is shown, that atomization degree of the separated isotopes limited real separation coefficient. The better buffer gas purification allowed to increase the experimental separation factor of 22 Na and 24 Na isotopes up to 25. The new experimental set up allow to increase the separation efficiency up to 50%. 12 refs.; 5 figs

  12. Ingestão de energia e nutrientes segundo consumo de alimentos fora do lar na Região Nordeste: uma análise do Inquérito Nacional de Alimentação 2008-2009

    Directory of Open Access Journals (Sweden)

    Jessica Brito Cavalcante

    Full Text Available RESUMO: Introdução: O consumo de alimentos fora do lar vem crescendo no Brasil, sendo associado a escolhas alimentares menos nutritivas. Objetivo: Descrever a ingestão de energia e nutrientes específicos entre consumidores e não consumidores de alimentos fora do lar, na Região Nordeste. Métodos: Foram analisados dados do Inquérito Nacional de Alimentação (INA, provenientes da Pesquisa de Orçamentos Familiares (POF 2008-2009, em uma amostra de 11.674 indivíduos residentes na Região Nordeste, que forneceram dois registros alimentares em dias não consecutivos, com informação sobre o local de consumo dos alimentos (dentro ou fora do lar. Alimentação fora do lar foi definida como todo alimento adquirido e consumido fora de casa. Modelos de regressão linear foram desenvolvidos para avaliar a relação entre o consumo alimentar fora do lar em um dos dois dias de registro e a ingestão de energia e nutrientes, ajustados por idade, sexo e renda per capita. Resultados: O consumo de alimentos fora do lar, em pelo menos um dos dois dias de registro alimentar, foi reportado por 42% dos indivíduos. Os indivíduos que consomem alimentos fora do lar apresentaram pior ingestão de nutrientes em comparação com os que não consomem alimentos fora do lar, com maior consumo de energia, açúcar livre, gordura saturada, gordura trans e menor ingestão de proteína, ferro e fibra alimentar, independente da idade, sexo e renda (p < 0,05. Conclusão: A alimentação fora do lar no Nordeste contribuiu para uma maior ingestão de energia e uma pior ingestão de nutrientes. Assim, faz-se necessária a elaboração de políticas públicas e estratégias que favoreçam a escolha de alimentos mais saudáveis quando os indivíduos optam por se alimentar fora do lar.

  13. Intracellular Na+ regulation of Na+ pump sites in cultured vascular smooth muscle cells

    International Nuclear Information System (INIS)

    Allen, J.C.; Navran, S.S.; Seidel, C.L.; Dennison, D.K.; Amann, J.M.; Jemelka, S.K.

    1989-01-01

    Enzymatically dispersed cells from canine saphenous vein and femoral artery were grown in fetal calf serum and studied at day 0 (freshly dispersed) through confluence in primary culture. Intracellular Na levels (Nai), but not intracellular K (Ki), were increased after 24 h in culture and then decreased to a steady state by 4 days. Na+ pump site number [( 3 H] ouabain binding) increased through day 3 and remained elevated. Nai was still elevated at 2 days when the Na+ pump site number began to increase. Total pump turnover (maximum ouabain-inhibited 86 Rb uptake) reflected the increase in Na+ pump site number. These key events precede the observed increases in both protein production and cellular proliferation. If the same cells are maintained in defined medium, without fetal calf serum, Nai, Ki, and the number of [ 3 H]ouabain binding sites do not change with time. These data are consistent with the suggestion that the initial mitogenic response of vascular smooth muscle cells to fetal calf serum involves an increased Na+ influx, and a Nai accumulation, caused by low Na+ pump density. The synthesis of new pump sites effects a decrease in the accumulated Nai, which may be related to cell proliferation

  14. Vliv mikroflóry na senzorické vlastnosti vína

    OpenAIRE

    Petrášová, Ludmila

    2014-01-01

    Tato bakalářská práce se zabývá vlivem mikroflóry na senzorické vlastnosti vína. Teoretická část informuje o botanickém popisu hroznů vína Veltlínské zelené, dále o jeho složení, o technologii zpracování bílého vína a o vlivu kvasinek na aromatický profil vína. V další části popisuje metodu stanovení aromaticky aktivních látek pomocí plynové chromatografie v kombinaci s mikroextrakcí tuhou fází (SPME-GC). Cílem experimentální části bylo proměřit vzorky 4 různých moštů odrůdy Veltlínské zelené...

  15. Active transport of Na/sup +/ by reconstituted Na,K-ATPase

    Energy Technology Data Exchange (ETDEWEB)

    Boldyrev, A.A.; Svinukhova, I.A.

    1987-02-20

    The ability of ATP, CTP, ITP, GTP, and UTP to support ouabain-sensitive accumulation of Na/sup +/ by proteoliposomes with a reconstituted Na/K-pump was investigated. At a low (Na/sup +/)/(K/sup +/) ratio in the medium (20 mM/50 mM), a correlation is observed between the proton-accepting capacity of the nucleotide and its effectiveness as a substrate of active transport. To test the hypothesis of the importance of the presence of a negative charge in the 1-position of the purine (3-pyrimidine) base of the nucleotide for mutual transitions between the Na- and K-conformations of Na,K-ATPase they used two analogs of ATP: N/sub 1/-hydroxy-ATP, possessing proton acceptor capacity, and N/sub 1/-methoxy-ATP, in the molecule of which the negative charge is quenched by a methyl group. The first substrate supports active accumulation of Na/sup +/ in proteoliposomes at the same rate as ATP, whereas the second substrate is relatively ineffective.

  16. Transport of Na48 Drift Chambers to Dubna

    CERN Multimedia

    GOLOVATYUK, V

    2010-01-01

    On 22 July, in the occasion of the departure of the Na48 Drift Chambers from CERN, Mikhail Itkis (acting Director of the JIINR) and Rolf Heuer (CERN Director General) visited the NA62 experimental area.

  17. Regulation of Epithelial Sodium Transport via Epithelial Na+ Channel

    Science.gov (United States)

    Marunaka, Yoshinori; Niisato, Naomi; Taruno, Akiyuki; Ohta, Mariko; Miyazaki, Hiroaki; Hosogi, Shigekuni; Nakajima, Ken-ichi; Kusuzaki, Katsuyuki; Ashihara, Eishi; Nishio, Kyosuke; Iwasaki, Yoshinobu; Nakahari, Takashi; Kubota, Takahiro

    2011-01-01

    Renal epithelial Na+ transport plays an important role in homeostasis of our body fluid content and blood pressure. Further, the Na+ transport in alveolar epithelial cells essentially controls the amount of alveolar fluid that should be kept at an appropriate level for normal gas exchange. The epithelial Na+ transport is generally mediated through two steps: (1) the entry step of Na+ via epithelial Na+ channel (ENaC) at the apical membrane and (2) the extrusion step of Na+ via the Na+, K+-ATPase at the basolateral membrane. In general, the Na+ entry via ENaC is the rate-limiting step. Therefore, the regulation of ENaC plays an essential role in control of blood pressure and normal gas exchange. In this paper, we discuss two major factors in ENaC regulation: (1) activity of individual ENaC and (2) number of ENaC located at the apical membrane. PMID:22028593

  18. An enhancement to the NA4 gear vibration diagnostic parameter

    Science.gov (United States)

    Decker, Harry J.; Handschuh, Robert F.; Zakrajsek, James J.

    1994-01-01

    A new vibration diagnostic parameter for health monitoring of gears, NA4*, is proposed and tested. A recently developed gear vibration diagnostic parameter NA4 outperformed other fault detection methods at indicating the start and initial progression of damage. However, in some cases, as the damage progressed, the sensitivity of the NA4 and FM4 parameters tended to decrease and no longer indicated damage. A new parameter, NA4* was developed by enhancing NA4 to improve the trending of the parameter. This allows for the indication of damage both at initiation and also as the damage progresses. The NA4* parameter was verified and compared to the NA4 and FM4 parameters using experimental data from single mesh spur and spiral bevel gear fatigue rigs. The primary failure mode for the test cases was naturally occurring tooth surface pitting. The NA4* parameter is shown to be a more robust indicator of damage.

  19. Agmag Igbo dka Ngwar n'kwalite Ezi Nchekwa na Nkwsiike haobodo

    African Journals Online (AJOL)

    Ka Najira nwerechara onwe ya n'af 1960, olileanya tt mamala ya b na ihe ga-adz mma. Mana ka oge na-aga, a chptara na ihe na-akawanye nj. Usoro chch d iche iche daptara. Nd am na nd nkt achala mana nd gara n'ihu na-akawanye nj. O bu ihe doro anya na chch ha b nke nchgbu na fnfju akpa. N'agbanyegh na ...

  20. Angiotensin II-induced hypertension increases plasma membrane Na pump activity by enhancing Na entry in rat thick ascending limbs.

    Science.gov (United States)

    Gonzalez-Vicente, Agustin; Garvin, Jeffrey L

    2013-11-01

    Thick ascending limbs (TAL) reabsorb 30% of the filtered NaCl load. Na enters the cells via apical Na-K-2Cl cotransporters and Na/H exchangers and exits via basolateral Na pumps. Chronic angiotensin II (ANG II) infusion increases net TAL Na transport and Na apical entry; however, little is known about its effects on the basolateral Na pump. We hypothesized that in rat TALs Na pump activity is enhanced by ANG II-infusion, a model of ANG II-induced hypertension. Rats were infused with 200 ng·kg(-1)·min(-1) ANG II or vehicle for 7 days, and TAL suspensions were obtained. We studied plasma membrane Na pump activity by measuring changes in 1) intracellular Na (Nai) induced by ouabain; and 2) ouabain-sensitive oxygen consumption (QO2). We found that the ouabain-sensitive rise in Nai in TALs from ANG II-infused rats was 12.8 ± 0.4 arbitrary fluorescent units (AFU)·mg(-1)·min(-1) compared with only 9.9 ± 1.1 AFU·mg(-1)·min(-1) in controls (P Na pump expression, the number of Na pumps in the plasma membrane, or the affinity for Na. When furosemide (1.1 mg·kg(-1)·day(-1)) was coinfused with ANG II, no increase in plasma membrane Na pump activity was observed. We concluded that in ANG II-induced hypertension Na pump activity is increased in the plasma membrane of TALs and that this increase is caused by the chronically enhanced Na entry occurring in this model.

  1. Rescue of Na+ affinity in aspartate 928 mutants of Na+,K+-ATPase by secondary mutation of glutamate 314.

    Science.gov (United States)

    Holm, Rikke; Einholm, Anja P; Andersen, Jens P; Vilsen, Bente

    2015-04-10

    The Na(+),K(+)-ATPase binds Na(+) at three transport sites denoted I, II, and III, of which site III is Na(+)-specific and suggested to be the first occupied in the cooperative binding process activating phosphorylation from ATP. Here we demonstrate that the asparagine substitution of the aspartate associated with site III found in patients with rapid-onset dystonia parkinsonism or alternating hemiplegia of childhood causes a dramatic reduction of Na(+) affinity in the α1-, α2-, and α3-isoforms of Na(+),K(+)-ATPase, whereas other substitutions of this aspartate are much less disruptive. This is likely due to interference by the amide function of the asparagine side chain with Na(+)-coordinating residues in site III. Remarkably, the Na(+) affinity of site III aspartate to asparagine and alanine mutants is rescued by second-site mutation of a glutamate in the extracellular part of the fourth transmembrane helix, distant to site III. This gain-of-function mutation works without recovery of the lost cooperativity and selectivity of Na(+) binding and does not affect the E1-E2 conformational equilibrium or the maximum phosphorylation rate. Hence, the rescue of Na(+) affinity is likely intrinsic to the Na(+) binding pocket, and the underlying mechanism could be a tightening of Na(+) binding at Na(+) site II, possibly via movement of transmembrane helix four. The second-site mutation also improves Na(+),K(+) pump function in intact cells. Rescue of Na(+) affinity and Na(+) and K(+) transport by second-site mutation is unique in the history of Na(+),K(+)-ATPase and points to new possibilities for treatment of neurological patients carrying Na(+),K(+)-ATPase mutations. © 2015 by The American Society for Biochemistry and Molecular Biology, Inc.

  2. Characterization of Na+-linked and Na+-independent Cl-/HCO3- exchange systems in Chinese hamster lung fibroblasts

    International Nuclear Information System (INIS)

    Cassel, D.; Scharf, O.; Rotman, M.; Cragoe, E.J. Jr.; Katz, M.

    1988-01-01

    The PS120 variant of Chinese hamster lung fibroblasts which lacks Na + /H + exchange activity was used to investigate bicarbonate transport systems and their role in intracellular pH (pH/sub i/) regulation. When pH/sub i/ was decreased by acid load, bicarbonate caused pH/sub i/ increase and stimulated 36 Cl - efflux from the cells, both in a Na + -dependent manner. These results together with previous findings that bicarbonate stimulates 22 Na + uptake in PS120 cells demonstrate the presence of a Na + -linked Cl - /HCO 3 - exchange system. In cells with normal initial pH/sub i/, bicarbonate caused Na + -independent pH/sub i/ increase in Cl - -free solutions and stimulated Na + -independent 36 Cl - efflux, indicating that a Na + -independent Cl - /HCO 3 - exchanger is also present in the cell. Na + -linked and Na + -independent Cl - /HCO 3- exchange is apparently mediated by two distinct systems, since a [(tetrahydrofluorene-7-yl)oxy]acetic acid derivative selectively inhibits the Na + -independent exchanger. An additional distinctive features is a 10-fold lower affinity for chloride of the Na + -linked exchanger. The Na + -linked and Na + -independent Cl - /HCO 3 - exchange systems are likely to protect the cell from acid and alkaline load, respectively

  3. The two C-terminal tyrosines stabilize occluded Na/K pump conformations containing Na or K ions.

    Science.gov (United States)

    Vedovato, Natascia; Gadsby, David C

    2010-07-01

    Interactions of the three transported Na ions with the Na/K pump remain incompletely understood. Na/K pump crystal structures show that the extended C terminus of the Na,K-adenosine triphosphatase (ATPase) alpha subunit directly contacts transmembrane helices. Deletion of the last five residues (KETYY in almost all Na/K pumps) markedly lowered the apparent affinity for Na activation of pump phosphorylation from ATP, a reflection of cytoplasmic Na affinity for forming the occluded E1P(Na3) conformation. ATPase assays further suggested that C-terminal truncations also interfere with low affinity Na interactions, which are attributable to extracellular effects. Because extracellular Na ions traverse part of the membrane's electric field to reach their binding sites in the Na/K pump, their movements generate currents that can be monitored with high resolution. We report here electrical measurements to examine how Na/K pump interactions with extracellular Na ions are influenced by C-terminal truncations. We deleted the last two (YY) or five (KESYY) residues in Xenopus laevis alpha1 Na/K pumps made ouabain resistant by either of two kinds of point mutations and measured their currents as 10-mM ouabain-sensitive currents in Xenopus oocytes after silencing endogenous Xenopus Na/K pumps with 1 microM ouabain. We found the low affinity inhibitory influence of extracellular Na on outward Na/K pump current at negative voltages to be impaired in all of the C-terminally truncated pumps. Correspondingly, voltage jump-induced transient charge movements that reflect pump interactions with extracellular Na ions were strongly shifted to more negative potentials; this signals a several-fold reduction of the apparent affinity for extracellular Na in the truncated pumps. Parallel lowering of Na affinity on both sides of the membrane argues that the C-terminal contacts provide important stabilization of the occluded E1P(Na3) conformation, regardless of the route of Na ion entry into the

  4. The rapid-onset dystonia parkinsonism mutation D923N of the Na+, K+-ATPase alpha3 isoform disrupts Na+ interaction at the third Na+ site.

    Science.gov (United States)

    Einholm, Anja Pernille; Toustrup-Jensen, Mads S; Holm, Rikke; Andersen, Jens Peter; Vilsen, Bente

    2010-08-20

    Rapid-onset dystonia parkinsonism (RDP), a rare neurological disorder, is caused by mutation of the neuron-specific alpha3-isoform of Na(+), K(+)-ATPase. Here, we present the functional consequences of RDP mutation D923N. Relative to the wild type, the mutant exhibits a remarkable approximately 200-fold reduction of Na(+) affinity for activation of phosphorylation from ATP, reflecting a defective interaction of the E(1) form with intracellular Na(+). This is the largest effect on Na(+) affinity reported so far for any Na(+), K(+)-ATPase mutant. D923N also affects the interaction with extracellular Na(+) normally driving the E(1)P to E(2)P conformational transition backward. However, no impairment of K(+) binding was observed for D923N, leading to the conclusion that Asp(923) is specifically associated with the third Na(+) site that is selective toward Na(+). The crystal structure of the Na(+), K(+)-ATPase in E(2) form shows that Asp(923) is located in the cytoplasmic half of transmembrane helix M8 inside a putative transport channel, which is lined by residues from the transmembrane helices M5, M7, M8, and M10 and capped by the C terminus, recently found involved in recognition of the third Na(+) ion. Structural modeling of the E(1) form of Na(+), K(+)-ATPase based on the Ca(2+)-ATPase crystal structure is consistent with the hypothesis that Asp(923) contributes to a site binding the third Na(+) ion. These results in conjunction with our previous findings with other RDP mutants suggest that a selective defect in the handling of Na(+) may be a general feature of the RDP disorder.

  5. Jogos teatrais na escola pública

    Directory of Open Access Journals (Sweden)

    Ricardo Ottoni Vaz Japiassu

    1998-07-01

    Full Text Available O artigo apresenta os resultados parciais de pesquisa etnográfica que acompanha aspectos do desenvolvimento cultural de pré-adolescentes com a linguagem teatral em classe multisseriada, através do ensino regular de Teatro, em escola de ensino fundamental da rede pública estadual de São Paulo-SP. Os dados obtidos permitem afirmar que a linguagem cênica contribui na conscientização das novas possibilidades de significação da palavra na prática discursiva.The article shows partial results of ethnographic research in which kids are observed in their cultural development process with theater classes in public school education in São Paulo/Brazil. The data colected indicates that the use of theater games in school education helps students to be aware of a word’s new meaning possibilities in human comunication.

  6. Luz e tempo na melancolia I

    Directory of Open Access Journals (Sweden)

    Cláudio Soares Braga Furtado

    2009-12-01

    Full Text Available A comparação entre as artes possibilita figurar o tempo como elemento comum entre a gravura renascentista de Dürer, a escultura romana de Laocoonte e o conto de Guimarães Rosa. A partir da leitura dessas artes distantes em forma, meios, época e lugar, descobrem-se mistérios aludidos em sutis sinais, que, se ainda não despertos na consciência criativa, estimulam interpretações. O papel da luz como unificadora das entidades tempo/espaço restabelece o princípio clássico da ut pictura poesis na leitura moderna.

  7. NA62 experiment at CERN SPS

    Directory of Open Access Journals (Sweden)

    Kozhuharov Venelin

    2014-01-01

    Full Text Available The NA62 experiment at SPS is a continuation of the long standing CERN kaon physics program. The high statistics and the unprecedent precision allow to probe the Standard Model and test the description of the strong interactions at low energy. The final results on the the lepton universality test by measuring the ratio RK = Γ(K+ → e+ν/Γ(K+ → µ+ν and the study of the K± → π±γγ decay are presented. The major goal of the NA62 experiment is to perform a measurement of the Br(K+ → π+νν̄ with a precision of 10% in two years of data taking. The detector setup together with the analysis technique is described.

  8. O Personal Trainer na Perspectiva do Marketing

    Directory of Open Access Journals (Sweden)

    Cibele Biehl Bossle

    2011-03-01

    Full Text Available Esse estudo apresenta mapeamento das referências dedicadas à formação do personal trainer em bases de dados eletrônicas. Essa garimpagem revelou baixa produção científica sobre o assunto e mostrou que na literatura sobre personal trainer predominam livros com linguagem corrente no mundo dos negócios. Esses achados nos levaram a indagar sobre a força do discurso físico-empresarial, especialmente o marketing, na constituição desta ocupação profissional. Jeremy Rifkin, Zygmunt Bauman, Paula Sibilia e Denise Sant'Anna permitiram visualizar que o marketing dirigido ao personal trainer tem como tarefa reinventar, ressignificar e "repaginar" esta modalidade de serviço em nome da sobrevivência no disputado mercado da vida ativa.

  9. Algoritmo de lanczos na variedade de grassmann

    OpenAIRE

    Lopes, Ana Paula Ferreira Fernandes; Viamonte, Ana Júlia; Pascoal, António José

    2008-01-01

    O problema do cálculo de valores próprios, vectores próprios e subespaços invariantes está presente em áreas tão diversas como Engenharia, Física, Ciências de Computação e Matemática. Considerando a importância deste problema em tantas aplicações práticas, não é de surpreender que tenha sido e continue a ser objecto de intensa investigação, dando corpo a uma literatura muito vasta. Desenvolvemos um novo algoritmo de Lanczos na variedade de Grassmann. Este trabalho surgiu na ...

  10. Kaizen: Uma Metodologia Inovadora na Siderurgia

    Directory of Open Access Journals (Sweden)

    Hericson Estanislau Prata

    2017-04-01

    Full Text Available A racionalização do processo produtivo industrial, por meio da redução dos desperdícios e da modernização do processo produtivo, com a adoção do Sistema Toyota de Produção (Produção Enxuta, tem sido adotada por uma parte importante das indústrias no mundo. O objetivo deste artigo é descrever essa metodologia empregada pelo grupo de melhoria de fase intensiva adotado na Vallourec Tubos do Brasil S.A. Como resultado, verificou-se que o processo utilizado para a implantação de mudanças em curto prazo foi a semana intensiva, também conhecida como evento Kaizen na indústria automotiva.

  11. The NA60 experiment readout architecture

    CERN Document Server

    Floris, M; Usai, G L; David, A; Rosinsky, P; Ohnishi, H

    2004-01-01

    The NA60 experiment was designed to identify signatures of a new state of matter, the Quark Gluon Plasma, in heavy-ion collisions at the CERN Super Proton Synchroton. The apparatus is composed of four main detectors: a muon spectrometer (MS), a zero degree calorimeter (ZDC), a silicon vertex telescope (VT), and a silicon microstrip beam tracker (BT). The readout of the whole experiment is based on a PCI architecture. The basic unit is a general purpose PCI card, interfaced to the different subdetectors via custom mezzanine cards. This allowed us to successfully implement several completely different readout protocols (from the VME like protocol of the MS to the custom protocol of the pixel telescope). The system was fully tested with proton and ion beams, and several million events were collected in 2002 and 2003. This paper presents the readout architecture of NA60, with particular emphasis on the PCI layer common to all the subdetectors. (16 refs).

  12. Urgências reprodutivas na cadela

    OpenAIRE

    Costa, Teresa Isabel Rodrigues da

    2010-01-01

    Dissertação de Mestrado Integrado em Medicina Veterinária As urgências reprodutivas ocorrem com frequência na prática clínica, estando o seu desfecho favorável associado a um diagnóstico e intervenção céleres. Na cadela, consideram-se urgências reprodutivas a distócia, a piómetra, o prolapso uterino, a torção uterina, a tetania puerperal, a metrite e a mastite. Esta dissertação tem por base a análise dos dados referentes à casuística de urgências reprodutivas em cadelas veri...

  13. NA35: sulphur-gold collision

    CERN Multimedia

    1991-01-01

    In this image the real particles produced by the collision of a 6400 GeV sulphur ion with a gold target can be seen as they pass through a streamer chamber. Streamer chambers consist of a gas chamber through which a strong pulsed electric field is passed, creating sparks as a charged particle passes through it. The NA35 experiment, which was in operation in the 1980s, was part of CERN's ongoing heavy ion project.

  14. New NA22 results on correlations

    International Nuclear Information System (INIS)

    De Wolf, E.A.

    1993-01-01

    Recent NA22 results from π + p and K + p inelastic interactions at √s = 22 GeV on invariant-mass and Q 2 -dependence of two- and three-particle factorial cumulants are discussed in relation to earlier intermittency studies. The absence of Bose-Einstein type correlations among identical particles, and too large resonance production rates, are responsible for the strong disagreements of models with intermittency data. 6 figs., 17 refs

  15. O legado grego na terminologia gramatical brasileira

    Directory of Open Access Journals (Sweden)

    Maria Helena de Moura Neves

    2011-12-01

    Full Text Available Este estudo tem como objetivo pesquisar a existência de um legado grego terminológico na organização gramatical brasileira, considerando que a gramática incipiente grega é a fonte da nossa gramática, por via da gramática latina, e que o recorte de campo que ela preparou é um ponto de referência para o estudo da evolução do pensamento ocidental sobre a linguagem. A orientação teórico-metodológica se assenta na Linguística Histórica, na linha que orientou a ampla pesquisa sobre a emergência da gramática no Ocidente que constitui a fonte das informações que aqui se organizam (NEVES, 2005. As reflexões dirigem-se especialmente para o exame da nomenclatura, entendendo que ela mapeia conceptualmente o conjunto das posições assumidas, e em geral mantidas, que merecem apreciação. Entre outras coisas o exame opôs: termos gregos legados na corrente contínua do pensamento gramatical a termos gregos introduzidos posteriormente; termos transliterados do grego a termos decalcados da tradução latina. Além disso, verificaram-se casos de alteração de nome com manutenção de conceito, e casos de alteração de conceito para um nome conservado. De todo modo, o exame da nomenclatura revela a indiscutível existência de um legado grego à organização da gramática portuguesa.

  16. Isovector magnetic dipole transition in 22Na

    International Nuclear Information System (INIS)

    Fifield, L.K.; Poletti, A.R.; Radford, D.C.

    1980-01-01

    The mean life of the 657 keV 0 + , T = 1 level in 22 Na for the radiative decay to the 583 keV 1 + , T = 0 level has been measured as tau = (27.1 +- 1.2)ps. A modification of the recoil-distance method (RDM) was used. In addition, the mean life of the 891 keV level in the same nucleus was remeasured to give tau = (14.1 +- 0.5)ps. (author)

  17. Prototype calorimeters for the NA3 experiment

    CERN Multimedia

    1975-01-01

    The NA3 Experiment was set-up on the North Area of the SPS by the CERN/ Ecole Polytechnique/College de France/ Orsay/Saclay Collaboration, to study high transverse momentum leptons and hadrons from hadron collisions. The calorimeters measured the energy of hadrons (prototype on the right) and leptons (prototype on the left). They used a new type of plastic scintillator (plexipop). (see CERN Courier of November 1975) energy (prototype on the right)

  18. The NA48 liquid krypton calorimeter

    CERN Document Server

    Gorini, B

    1997-01-01

    The NA48 collaboration goal is to measure the CP violation parameter Re(ɛl/ɛ) at the level of 2 × 10−4. The neutral Kaon decays will be reconstructed by an electromagnetic liquid Krypton calorimeter with fine granularity and a volume almost totally sensible, to obtain excellent position and energy resolution, as well as time resolution. A description of the detector, results from tests of a prototype and the status of the final calorimeter are reported.

  19. Maendeleo ya Fasihi ya Kiswahili ya Watoto nchini Tanzania na ...

    African Journals Online (AJOL)

    Fasihi ya Kiswahili ya watoto kama taaluma haina muda mrefu katika historia ya fasihi ya Kiswahili. Ikilinganishwa na fasihi ya watu wazima ambayo ilianza muda mrefu, na pia tafiti nyingi kufanyika katika mataifa mengi, fasihi ya watoto inaonekana kuwa imetelekezwa kwa muda mrefu kutokana na kutokupewa umuhimu ...

  20. Dhima za Mbinu Linganishi katika Kuhusisha Lugha na Lahaja ...

    African Journals Online (AJOL)

    Lengo la makala hii ni kujadili dhima za Mbinu Linganishi katika kuhusisha lugha na lahaja. Data za makala hii zilikusanywa kwa kutumia mbinu mbalimbali ambazo ni usaili, ushuhudiaji, hojaji na majadiliano katika majopo. Utafiti ulifanyika Tanzania Bara hususan Mkoani Mtwara na Tanzania Visiwani katika maeneo ya ...

  1. VARSTVO DOSTOJANSTVA DELAVCA IN JAVNEGA USLUŽBENCA NA DELU

    OpenAIRE

    Trstenjak, Jasna

    2011-01-01

    V magistrski nalogi sem želela proučiti varstvo dostojanstva delavca in javnega uslužbenca na delu, saj menim, da je to ključen dejavnik v delovnem razmerju vsakega posameznika, prav tako ima neposreden vpliv na konkurenčno sposobnost kot tudi na stroške dela, tako v javnem kot v zasebnem sektorju.

  2. Efficacy of 22Na turnover in ecopbysiological studies of carnivores

    African Journals Online (AJOL)

    Efficacy of 22Na turnover in ecopbysiological studies of carnivores. loS. Wilkinson and J.D. Skinner*. Mammal Research Institute, University of Pretoria, Pretoria, 0002 Republic of South Africa. Received 8 December 1986; accepted 11 August 1987. 22Na turnover rates gave overestimates of mean 23Na intake in both ...

  3. UREDITEV SPOLNEGA NADLEGOVANJA NA DELOVNEM MESTU V REPUBLIKI SLOVENIJI

    OpenAIRE

    Golavšek, Nastja

    2009-01-01

    V diplomski nalogi je predstavljena problematika spolnega nadlegovanja na delovnem mestu. Spolno nadlegovanje je nezaželeno ravnanje spolne narave ali drugo ravnanje, temelječe na spolu, ki ogroža dostojanstvo žensk in moških na delovnem mestu

  4. Muundo wa Mashairi katika Diwani ya Mnyampala (1965) na Nafasi ...

    African Journals Online (AJOL)

    Makala hii pia inadadisi namna mbinu za kimuundo zilivyofanikisha usawiri na ubainishaji wa falsafa ya mtunzi kuhusu ushairi wa Kiswahili na nafasi ya ushairi katika jamii. Makala imeanza kwa kugusia usuli wa historia ya ushairi wa Kiswahili, historia fupi ya maisha ya Mathias Mnyampala na nadharia yake kuhusu ...

  5. Explosive phenomena in heavily irradiated NaCl

    NARCIS (Netherlands)

    denHartog, HW; Vainshtein, DI; Matthews, GE; Williams, RT

    1997-01-01

    In heavily irradiated NaCl crystals explosive phenomena can be initiated during irradiation or afterwards when samples are heated to temperatures between 100 and 250 degrees C. During irradiation of NaCl Na and Cl-2 precipitates and void structures are produced along with the accumulation of stored

  6. NaI(Tl) response functions

    International Nuclear Information System (INIS)

    Vega C, H. R.; Ortiz R, J. M.; Benites R, J. L.; De Leon M, H. A.

    2015-09-01

    The response functions of a NaI(Tl) detector have been estimated using Monte Carlo methods. Response functions were calculated for monoenergetic photon sources (0.05 to 3 MeV). Responses were calculated for point-like sources and for sources distributed in Portland cement cylinders. The responses were used to calculate the efficiency functions in term of photon energy. Commonly, sources used for calibration are point-like, and eventually sources to be measured have different features. In order to use the calibrated sources corrections due to solid angle, self-absorption and scattering, must be carried out. However, some of these corrections are not easy to perform. In this work, the calculated responses were used to estimate the detector efficiency of point-like sources, and sources distributed in Portland type cement. Samples of Portland paste were prepared and were exposed to photoneutrons produced by a 15 MV linac. Some of the elements in the cement were activated producing γ-emitting radionuclides that were measured with a NaI(Tl) gamma-ray spectrometer, that was calibrated with point-like sources. In order to determine the specific activity in the induced radioisotopes calculated efficiencies were used to make corrections due to the differences between the solid angle, photon absorption and photon scattering in the point-like calibration sources and the sources distributed in cement. During the interaction between photoneutrons and the cement samples three radioisotopes were induced: 56 Mn, 24 Na, and 28 Al. (Author)

  7. Cultura Política na Antiguidade

    Directory of Open Access Journals (Sweden)

    José Petrúcio Farias Júnior

    2009-06-01

    Full Text Available

    Pretendemos discutir nesse artigo algumas implicações do termo cultura política na Antiguidade, especificamente, na sociedade romana imperial. Dessa forma, acreditamos que as considerações que apresentaremos a seguir contribuam para reflexão da utilização desse termo, produto das investigações contemporâneas, sobre os estudos das sociedades antigas. Para a historiadora Profa. Dra. Margarida Maria de Carvalho, tais reflexões representam ainda uma lacuna na historiografia concernente a essa temática. Isso posto, discorreremos, inicialmente, sobre o conceito de cultura e seus desdobramentos para, em seguida, refletirmos sobre o viés interpretativo que fundamenta estudos históricos que se desenvolvem sob o beneplácito da linha de pesquisa intitulada História e Cultura Política.

  8. NaI Detector Network at Aragats

    International Nuclear Information System (INIS)

    Avakyan, Karen; Arakelyan, Karen; Chilingarian, Ashot; Daryan, Ara; Kozliner, Lev; Mailyan, Bagrat; Hovsepyan, Gagik; Pokhsraryan, David; Sargsyan, David

    2013-01-01

    The Aragats Space Environmental Center (ASEC) provides monitoring of different species of secondary cosmic rays and consists of two high altitude research stations on Mt. Aragats in Armenia. Along with solar modulation effects, ASEC detectors register several coherent enhancements associated with thunderstorm activity. The experimental techniques used allowed for the first time to simultaneously measure fluxes of the electrons, muons, gamma rays, and neutrons correlated with thunderstorm activity. Ground-based observations by a complex of surface particle detectors, measuring in systematically and repeatable fashion, gamma quanta, electrons, muons and neutrons from atmospheric sources are necessary for proving the theory of particle acceleration and multiplication during thunderstorms. Energy spectra and correlations between fluxes of different particles, measured on Earth's surface address the important issues of research of the solar modulation effects and the atmospheric high-energy phenomena. In May 26 2011, launched 5 NaI(Tl) (thallium-doped sodium iodide) scintillation detectors and 1 plastic one in the new ASEC laboratory on Aragats to detect low energy gamma rays from the thunderclouds and short particle bursts. Including NaI(Tl) detectors in ASEC detectors system is of great importance for investigation thunderstorm phenomena because NaI(Tl) detectors have high efficiency of gamma ray detecting in comparison with plastic ones.

  9. NA64 Search for Dark Photons

    CERN Document Server

    Shiakas, Christos

    2017-01-01

    The NA64 experiment, known as P348 before official approval, was proposed to the CERN SPSC on January 2014 with main goal the search for the following decay modes A′ → invisible A′ → e−e+ (1) In March 2016 P348 was granted approval by the CERN Research Board and received the title NA64. Since having been promoted, the experiment has been conducting the searches the searches for the processes mentioned above at the CERN SPS. NA64 is a fixed target experiment which utilizes the active beam dump. The detection of rare processes is based on the missing energy techniques. Such techniques are used for particles whose interaction with the detector is very small, so that they escape the detection and carry away some energy. A significant missing energy in the experiment means that such particles are produced. The method of the search for the A′ → invisible decay is as follows. If the A′ exists it could be produced via the kinetic mixing with bremsstrahlung photons in the reaction of high-energy elec...

  10. Experimental Study of Na based Titanium Nanofluid-Water Reaction

    Energy Technology Data Exchange (ETDEWEB)

    Park, Gunyeop; Kim, Soo Jae; Baek, Jehyun; Kim, Hyun Soo; Oh, Sun Ryung; Park, Hyun Sun; Kim, Moo Hwan [POSTECH, Pohang (Korea, Republic of)

    2015-10-15

    In KALIMER-600, a sodium-cooled fast reactor designed by KAERI, thermal energy is transported from high-temperature liquid Na (526 .deg. C at 0.1 MPa) to low temperature water (230 .deg. C at - 19.5 MPa) through a heat exchanger. If any leakage or rupture occurs during the operation of this heat exchanger, highly pressurized liquid water can penetrate into the liquid Na channels; this contact should instantly cause SWR. As reaction continues, liquid water is soon vaporized by pressure drop and huge amount of reaction heat. This generated water vapor expands large reaction area and increases sodium-water vapor reaction process. Therefore, the rapid generation of reaction product (like H{sub 2}) and water vapor increases the system pressure that can cause the system failure in SFR. To reduce this strong chemical reaction phenomena between Na and water, some we have focused on suppressing the chemical reactivity of liquid Na by dispersing nanoparticles (NPs). For the real application of NaTiNF, the pressure change induced by NaTiNF-water reaction is compared with Na-water reaction in the present study. NaTiNF contains 100nm of Ti NPs at 0.2 vol. %. The reaction rate of NaTiNF-water reaction is also investigated as reaction temperature increases. Sodium-water vapor reaction (SVR) will occur when an SWR accident occurs in SFR. In this manner, NaTiNF-water vapor reaction is experimentally performed for ensuring the suppression of chemical reactivity of NaTiNF in contact with water vapor. In the basic step for reducing risk of an SWR in SFR, we have experimentally verified the suppressed chemical reactivity of liquid sodium using Ti NPs through SWR and SVR experiments. In SWR, Na based titanium nanofluid (NaTiNF) shows lower pressure change than Na. As T{sub R} increases, P{sub max} in Na-water reaction increases while NaTiNF does not. The reaction rate of NaTiNF shows twice slower than that of Na. In SVR, NaTiNF shows slower temperature increase than Na. The distinct

  11. Route, mechanism, and implications of proton import during Na+/K+ exchange by native Na+/K+-ATPase pumps

    Science.gov (United States)

    Vedovato, Natascia

    2014-01-01

    A single Na+/K+-ATPase pumps three Na+ outwards and two K+ inwards by alternately exposing ion-binding sites to opposite sides of the membrane in a conformational sequence coupled to pump autophosphorylation from ATP and auto-dephosphorylation. The larger flow of Na+ than K+ generates outward current across the cell membrane. Less well understood is the ability of Na+/K+ pumps to generate an inward current of protons. Originally noted in pumps deprived of external K+ and Na+ ions, as inward current at negative membrane potentials that becomes amplified when external pH is lowered, this proton current is generally viewed as an artifact of those unnatural conditions. We demonstrate here that this inward current also flows at physiological K+ and Na+ concentrations. We show that protons exploit ready reversibility of conformational changes associated with extracellular Na+ release from phosphorylated Na+/K+ pumps. Reversal of a subset of these transitions allows an extracellular proton to bind an acidic side chain and to be subsequently released to the cytoplasm. This back-step of phosphorylated Na+/K+ pumps that enables proton import is not required for completion of the 3 Na+/2 K+ transport cycle. However, the back-step occurs readily during Na+/K+ transport when external K+ ion binding and occlusion are delayed, and it occurs more frequently when lowered extracellular pH raises the probability of protonation of the externally accessible carboxylate side chain. The proton route passes through the Na+-selective binding site III and is distinct from the principal pathway traversed by the majority of transported Na+ and K+ ions that passes through binding site II. The inferred occurrence of Na+/K+ exchange and H+ import during the same conformational cycle of a single molecule identifies the Na+/K+ pump as a hybrid transporter. Whether Na+/K+ pump–mediated proton inflow may have any physiological or pathophysiological significance remains to be clarified. PMID

  12. Route, mechanism, and implications of proton import during Na+/K+ exchange by native Na+/K+-ATPase pumps.

    Science.gov (United States)

    Vedovato, Natascia; Gadsby, David C

    2014-04-01

    A single Na(+)/K(+)-ATPase pumps three Na(+) outwards and two K(+) inwards by alternately exposing ion-binding sites to opposite sides of the membrane in a conformational sequence coupled to pump autophosphorylation from ATP and auto-dephosphorylation. The larger flow of Na(+) than K(+) generates outward current across the cell membrane. Less well understood is the ability of Na(+)/K(+) pumps to generate an inward current of protons. Originally noted in pumps deprived of external K(+) and Na(+) ions, as inward current at negative membrane potentials that becomes amplified when external pH is lowered, this proton current is generally viewed as an artifact of those unnatural conditions. We demonstrate here that this inward current also flows at physiological K(+) and Na(+) concentrations. We show that protons exploit ready reversibility of conformational changes associated with extracellular Na(+) release from phosphorylated Na(+)/K(+) pumps. Reversal of a subset of these transitions allows an extracellular proton to bind an acidic side chain and to be subsequently released to the cytoplasm. This back-step of phosphorylated Na(+)/K(+) pumps that enables proton import is not required for completion of the 3 Na(+)/2 K(+) transport cycle. However, the back-step occurs readily during Na(+)/K(+) transport when external K(+) ion binding and occlusion are delayed, and it occurs more frequently when lowered extracellular pH raises the probability of protonation of the externally accessible carboxylate side chain. The proton route passes through the Na(+)-selective binding site III and is distinct from the principal pathway traversed by the majority of transported Na(+) and K(+) ions that passes through binding site II. The inferred occurrence of Na(+)/K(+) exchange and H(+) import during the same conformational cycle of a single molecule identifies the Na(+)/K(+) pump as a hybrid transporter. Whether Na(+)/K(+) pump-mediated proton inflow may have any physiological or

  13. Growth mechanism of NaClO 3 and NaBrO 3 crystals from aqueous ...

    Indian Academy of Sciences (India)

    A study of growth rates of NaClO3 and NaBrO3 has been carried out using a small growth cell by in situ observation. Normal growth rates of {100} faces of NaClO3 and {111} faces of NaBrO3 along ⟨ 110 ⟩ direction are measured under relatively high supersaturation ranging from 3–8%. In the initial stages of growth, {100}, ...

  14. Plant Defensins NaD1 and NaD2 Induce Different Stress Response Pathways in Fungi

    Directory of Open Access Journals (Sweden)

    Peter M. Dracatos

    2016-09-01

    Full Text Available Nicotiana alata defensins 1 and 2 (NaD1 and NaD2 are plant defensins from the ornamental tobacco that have antifungal activity against a variety of fungal pathogens. Some plant defensins interact with fungal cell wall O-glycosylated proteins. Therefore, we investigated if this was the case for NaD1 and NaD2, by assessing the sensitivity of the three Aspergillus nidulans (An O-mannosyltransferase (pmt knockout (KO mutants (An∆pmtA, An∆pmtB, and An∆pmtC. An∆pmtA was resistant to both defensins, while An∆pmtC was resistant to NaD2 only, suggesting NaD1 and NaD2 are unlikely to have a general interaction with O-linked side chains. Further evidence of this difference in the antifungal mechanism was provided by the dissimilarity of the NaD1 and NaD2 sensitivities of the Fusarium oxysporum f. sp. lycopersici (Fol signalling knockout mutants from the cell wall integrity (CWI and high osmolarity glycerol (HOG mitogen-activated protein kinase (MAPK pathways. HOG pathway mutants were sensitive to both NaD1 and NaD2, while CWI pathway mutants only displayed sensitivity to NaD2.

  15. Response of saliva Na/K ratio to changing Na supply of lactating cows under tropical conditions

    NARCIS (Netherlands)

    Thiangtum, Wandee; Schonewille, J Thomas; Verstegen, Martin Wa; Arsawakulsudhi, Supot; Rukkwamsuk, Theera; Hendriks, Wouter H

    BACKGROUND: Factorial determination of the sodium (Na) requirement of heat-stressed lactating cows is hindered by accurate estimates of the Na losses through sweat. Direct studies, therefore, may be needed requiring information on the time course of healthy animals to become Na depleted and the

  16. Response of saliva Na/K ratio to changing Na supply of lactating cows under tropical conditions

    NARCIS (Netherlands)

    Thiangtum, Wandee; Schonewille, Thomas J.; Verstegen, Martin W.A.; Arsawakulsudhi, Supot; Rukkwamsuk, Theera; Hendriks, Wouter H.

    2017-01-01

    BACKGROUND: Factorial determination of the sodium (Na) requirement of heat-stressed lactating cows is hindered by accurate estimates of the Na losses through sweat. Direct studies, therefore, may be needed requiring information on the time course of healthy animals to become Na depleted and the

  17. Polarization and collision velocity dependence of associative ionization in cold Na (3p)-Na(3p) collisions

    NARCIS (Netherlands)

    Meijer, H.A.J.

    1990-01-01

    We studied the polarization dependence of the associative ionization (AI) process Na(3p) + Na(3p) → Na2+ at collision velocities between 100 and 700 m/s (5 and 200 K), using linearly and circularly polarized light for the excitation. We found that the polarization dependence varies strongly in the

  18. Reactions of metal oxides with molten NaPO3 + NaCl mixtures

    International Nuclear Information System (INIS)

    Kovarskaya, E.N.; Mityakhina, V.S.; Rodionov, Yu.I.; Silin, M.Yu.

    1988-01-01

    We consider the dissolution mechanism for iron (III), europium(III), and tin(IV) oxides in molten NaPO 3 + NaCl that are responsible for the peak solubilities. We chose Fe 2 O 3 as the basic material since this occurs in large amounts around damaged metal structures in rock salt mines in a proposed zone for storing vitrified radioactive wastes. Solubility measurement and paper chromatography show that Fe 2 O 3 dissolves in molten NaPO 3 + NaCl in air by reaction with the solvent to give double iron and sodium diphosphates and monophosphates in accordance with the initial solution-in-the-melt composition, the degree of equilibration, and the temperature. The elevated solubilities for initial NaCl contents close to 30 mole % are due to sodium triphosphates and tricyclophosphates present in these melts. Moessbauer spectroscopy confirms that double iron, europium and tin diphosphates and monophosphates containing sodium occur in these chloride-polyphosphate melts

  19. A EXTENSÃO UNIVERSITÁRIA E A LUDICIDADE NA EDUCAÇÃO INFANTIL CONTRA CRUELDADE ANIMAL E VIOLÊNCIA INTERPESSOAL

    Directory of Open Access Journals (Sweden)

    Daniel Cortes Beretta

    2016-08-01

    Full Text Available Resumo: A crueldade contra animais coexiste habitualmente com uma vasta gama de outros problemas (violência interpessoal, comportamento anti-social, bullying, etc. e pode ser identificada em crianças com idade inferior aos sete anos. A violência contra animais reflete diretamente na violência doméstica e interpessoale a crueldade contra seres indefesos e emocionalmente dependentes é parte de um ciclo insidioso de agressão. A formação de consciência crítica e individual se faz necessária nas etapas iniciais de vida do ser humano, portanto deve-se reconhecer e assumir que a criança é um ser social que constrói e cria cultura. O uso do lúdico através de jogos, teatros e brinquedos, é instrumento eficaz no desenvolvimento do pensamento e da autonomia infantil. Por isso, objetivou-se, através da ludicidade, que o público infantil aprendesse e transmitisse de forma adequada e segura, que os animais têm sentimentos; e que atos de crueldades contra eles não devem ser feitos ou repetidos. As atividades foram desenvolvidas de agosto de 2014 a novembro de 2015, nas cidades de Mineiros e Jataí, Goiás, Brasil. Foram realizadas ações pedagógicas aplicadas, como teatro, cantiga, cartilha educativa, brincadeiras interativas com massa de modelar e quebra-cabeça. Com a realização do projeto notou-se o interesse das crianças em aprender, transmitir a mensagem a seus familiares e, principalmente, colocar em prática o conhecimento adquirido por meio da dinâmica realizada. Como retorno, observou-se que a maneira lúdica e educativa foi eficiente em despertar o interesse das crianças contra a crueldade animal, quebrando neste caso o ciclo insidioso de violência. Palavras-chave: Extensão Universitária, bem estar animal, sensibilização, ensino fundamental.   The university extension and ludicity in early childhood education against animal cruelty and interpersonal violence Abstract: Animal cruelty usually coexists with other

  20. Sexualidade e conjugalidade: a redefinição das relações de gênero na França contemporânea Sexuality and conjugality: the redefinition of gender relations in contemporary France

    Directory of Open Access Journals (Sweden)

    Michel Bozon

    2003-01-01

    Full Text Available Um laço novo se estabeleceu entre sexualidade e vida conjugal nas últimas décadas do século XX. Tradicionalmente o direito à atividade sexual era adquirido com o estatuto de sujeito casado; hoje em dia, o intercâmbio sexual passou a ser o motor interno da conjugalidade. No entanto, esta inversão não gerou uma transformação completa das relações de gênero. A análise das mudanças dos comportamentos na França contemporânea mostra sem dúvida uma aproximação das trajetórias sexuais femininas e masculinas, e o desenvolvimento dum valor de reciprocidade entre parceiros. Mas o exame mais preciso do confronto dos homens e das mulheres nas várias etapas do intercâmbio sexual sugere a permanência de uma divergência de gênero: tanto a socialização adolescente como o curso da vida conjugal continuam sustentando interpretações muito assimétricas da sexualidade, nas quais o desejo feminino tem menos legitimidade do que o masculino.The relation between sexuality and conjugality has been deeply redefined in the last decades of the XXth century. Whereas sex was traditionally a right and an attribute of married people, sexual exchange has presently become the inner driving force in contemporary conjugality. Nevertheless, this reversal has not brought about radical shifts in gender relations. An analysis of trends in sexual behaviours in France doubtless shows the closing of the gap between male and female sexual trajectories and the rise of a value of reciprocity between partners. But a closer examination of the confronting of men and women at the various stages of sexual exchange suggests the permanence of a strong gender divergence: teen age socialization, as well as the very course of conjugal sex life continue fostering very assimetrical interpretations of sexuality, in which female desire is always less legitimate than the male one.

  1. MOBILNO POSLOVANJE NA PRIMERU UPORABE MICROSOFT DYNAMICS CRM

    OpenAIRE

    Duh, Tamara

    2016-01-01

    Hitro razvijajoči se svet nas spodbuja k hitremu reagiranju na novosti, ki se pojavljajo na trgu. Prav zaradi tega je danes zelo pomembno upravljati z mobilnimi napravami, da se lahko hitro in brez težav soočimo z morebitnimi težavami oz. zagatami. Prav iz tega razloga je mobilno poslovanje ena izmed inovativnih rešitev, ki ljudem omogoča seznanjenost z informacijami na vsakem koraku in omogoča hiter odziv na spremembe. Prav ta rešitev omogoča podjetjem, da so konkurenčna in hkrati lahko hitr...

  2. Predstave o seksu u filmovima na temu postapokalipse

    Directory of Open Access Journals (Sweden)

    Ana Banić-Grubišić

    2016-03-01

    Full Text Available Rad se bavi načinima predstavljanja seksualnih odnosa u filmovima na temu postapokalipse. Razmatraju se različiti oblici/vrste seksualnih veza, koje se javljaju u postkataklizmičnom okruženju, u odnosu na dva tipa zajednica/društava koja nastaju nakon kraja sveta. Ti filmovi pokazuju koliko je ideja o nagonskoj, prirodnoj, biološkoj seksualnosti raširena u popularnoj imaginaciji – seks je u postapokalipsi predstavljen kao pokretačka sila, na isti način kao što je to i glad.

  3. Usando a antimatéria na medicina moderna

    OpenAIRE

    Machado,A.C.B.; Pleitez,V.; Tijero,M.C.

    2006-01-01

    Neste artigo, fazemos uma breve exposição de como um dos conceitos fundamentais da física moderna, a existência de antimatéria, tem aplicação na medicina, na chamada tomografia por emissão de pósitrons (PET na sigla em inglês). Ela consiste na produção de imagens tomográficas digitais do organismo que são obtidas pela detecção da radiação produzida na aniquilação do pósitron com o elétron.

  4. Imenovanje jednonitnih homopolimera i kopolimera na osnovi podrijetla (I. dio

    Directory of Open Access Journals (Sweden)

    Vida Jarm

    2018-04-01

    Full Text Available Prethodne IUPAC-ove preporuke imenovanja (nomenklature jednonitnih polimera na osnovi podrijetla (NOP odnosile su se uglavnom na kopolimere, nelinearne polimere, združene polimere i generičke polimere. Pravila navedena u ovim preporukama omogućuju jasnije i preciznije imenovanje polimera na osnovi podrijetla, kako homopolimera tako i kopolimera. Prikazani sveobuhvatni sustav imenovanja polimera na osnovi podrijetla prihvatljiva je alternativa sustavu imenovanja polimera na osnovi strukture. Zbog raširene i česte uporabe dodatno su opisane i preporuke za uporabu uvriježenih imena polimera.

  5. Novel regulation of cardiac Na pump via phospholemman.

    Science.gov (United States)

    Pavlovic, Davor; Fuller, William; Shattock, Michael J

    2013-08-01

    As the only quantitatively significant Na efflux pathway from cardiac cells, the Na/K ATPase (Na pump) is the primary regulator of intracellular Na. The transmembrane Na gradient it establishes is essential for normal electrical excitability, numerous coupled-transport processes and, as the driving force for Na/Ca exchange, thus setting cardiac Ca load and contractility. As Na influx varies with electrical excitation, heart rate and pathology, the dynamic regulation of Na efflux is essential. It is now widely recognized that phospholemman, a 72 amino acid accessory protein which forms part of the Na pump complex, is the key nexus linking cellular signaling to pump regulation. Phospholemman is the target of a variety of post-translational modifications (including phosphorylation, palmitoylation and glutathionation) and these can dynamically alter the activity of the Na pump. This review summarizes our current understanding of the multiple regulatory mechanisms that converge on phospholemman and govern NA pump activity in the heart. The corrected Fig. 4 is reproduced below. The publisher would like to apologize for any inconvenience caused. [corrected]. Copyright © 2013. Published by Elsevier Ltd.

  6. Synthesis of zeolites Na-A and Na-X from tablet compressed and calcinated coal fly ash

    Science.gov (United States)

    Hu, Tao; Gao, Wenyan; Liu, Xin; Zhang, Yifu; Meng, Changgong

    2017-10-01

    Zeolites Na-A and Na-X are important synthetic zeolites widely used for separation and adsorption in industry. It is of great significance to develop energy-efficient routines that can synthesize zeolites Na-A and Na-X from low-cost raw materials. Coal fly ash (CFA) is the major residue from the combustion of coal and biomass containing more than 85% SiO2 and Al2O3, which can readily replace the conventionally used sodium silicate and aluminate for zeolite synthesis. We used Na2CO3 to replace the expensive NaOH used for the calcination of CFA and showed that tablet compression can enhance the contact with Na2CO3 for the activation of CFA through calcination for the synthesis of zeolites Na-A and Na-X under mild conditions. We optimized the control variables for zeolite synthesis and showed that phase-pure zeolite Na-A can be synthesized with CFA at reactant molar ratio, hydrothermal reaction temperature and reaction time of 1.3Na2O: 0.6Al2O3: 1SiO2: 38H2O at 80°C for 6 h, respectively, while phase-pure zeolite Na-X can be synthesized at 2.2Na2O: 0.2Al2O3: 1SiO2: 88H2O at 100°C for 8 h, respectively. The composition, morphology, specific surface area, vibration spectrum and thermogravimetry of synthesized Na-A and Na-X were further characterized.

  7. Synthesis of Na-A and/or Na-X zeolite/porous carbon composites from carbonized rice husk

    International Nuclear Information System (INIS)

    Katsuki, Hiroaki; Komarneni, Sridhar

    2009-01-01

    Na-A and/or Na-X zeolite/porous carbon composites were prepared under hydrothermal conditions by NaOH dissolution of silica first from carbonized rice husk followed by addition of NaAlO 2 and in situ crystallization of zeolites i.e., using a two-step process. When a one-step process was used, both Na-A and Na-X zeolites crystallized on the surface of carbon. Na-A or Na-X zeolite crystals were prepared on the porous carbonized rice husk at 90 deg. C for 2-6 h by changing the SiO 2 /Al 2 O 3 , H 2 O/Na 2 O and Na 2 O/SiO 2 molar ratios of precursors in the two-step process. The surface area and NH 4 + -cation exchange capacity (CEC) of Na-A zeolite/porous carbon were found to be 171 m 2 /g and 506 meq/100 g, respectively, while those of Na-X zeolite/porous carbon composites were 676 m 2 /g and 317 meq/100 g, respectively. Na-A and Na-X zeolites are well-known microporous and hydrophilic materials while carbonized rice husk was found to be mesoporous (pores of ∼3.9 nm) and hydrophobic. These hybrid microporous-mesoporous and hydrophilic-hydrophobic composites are expected to be useful for decontamination of metal cations as well as organic contaminants simultaneously. - Graphical Abstract: Novel Na-X zeolite/porous carbon composite.

  8. Integración de componentes genéticos y adquiridos en la cognición social

    OpenAIRE

    Garay, Carlos Alberto

    2011-01-01

    El ser humano reúne en sí una naturaleza biológica y una naturaleza cultural. Enfrentamos el problema de la fragmentación del conocimiento como consecuencia de la linealidad de las trayectorias de formación científica y la hiperespecialización. Más específicamente, enfrentamos los problemas derivados de la división entre ciencias naturales y ciencias sociales o humanas. Esta división proviene, en parte, de los fracasos de las estrategias reduccionistas de unificación de las ciencias (Agazzi, ...

  9. Paludismo por Plasmodium falciparum adquirido en África subsahariana Plasmodium falciparum malaria acquired in Subsaharian Africa

    Directory of Open Access Journals (Sweden)

    Ricardo Durlach

    2009-02-01

    Full Text Available El objetivo de este trabajo es presentar los casos de paludismo por Plasmodium falciparum ocurridos en viajeros provenientes del África tropical, atendidos en el Hospital Alemán. Se definió paludismo de origen africano como la infección adquirida en un país del África subsahariana, diagnosticado y tratado en la Argentina. El diagnóstico se realizó por la clínica y la microscopía óptica en frotis de sangre periférica coloreados con Giemsa. Se revieron las historias clínicas de 11 pacientes adultos -cinco turistas y seis marineros mercantes- no oriundos de área endémica, sin condición inmunosupresora, ni morbilidad asociada, internados entre 1993 y 2007. El rango de edad fue de 21 a 48 años; nueve hombres y dos mujeres. Los pacientes fueron clasificados retrospectivamente en malaria grave (seis o no grave (cinco según cumplieran con uno o más de los criterios de gravedad de la Organización Mundial de la Salud. Todos presentaron fiebre como signo más significativo. Como complicaciones graves se observaron casos de insuficiencia renal, epistaxis, hemoglobinuria, hipoglucemia, edema pulmonar, acidosis y coma. Tres pacientes requirieron internación en la unidad de terapia intensiva. Todos sobrevivieron y solamente tres habían recibido la quimioprofilaxis correcta antes de viajar. El tratamiento se realizó con una o más de las siguientes drogas: mefloquina, quinidina, clindamicina y cotrimoxazol.The purpose of this paper is to present the cases of malaria caused by Plasmodium falciparum in travelers coming from tropical Africa, who were treated at the Hospital Alemán (Buenos Aires. African malaria was defined as an infection acquired in any country within Africa, diagnosed and treated in Argentina. Diagnostic tools included clinical features and optic microscopy with Giemsa stained peripheral blood films. We reviewed the medical records of 11 adult patients -five tourists and six sailors- with no history of malaria, immunosuppressive condition or associated morbidity, admitted from 1993 to 2007. The age ranged from 21 to 48 years old, nine of them were males and two females. The patients were retrospectively classified into severe malaria -six of them- or mild malaria -five of them- according to severity criteria established by the World Health Organization, within the first three days of the beginnings of the symptoms. All patients presented fever; severe complications included encephalitis, renal failure, bleeding, haemoglobinuria, hypoglycemia, and pulmonary edema. Three patients required admission at the intensive care unit; no patient died. Only three off them had received properly chemoprophylaxis before traveling; all received treatment with at least one of the following drugs: mefloquine, quinidine, clyndamicine and cotrimoxazol.

  10. A evicção de bens adquiridos em hasta pública e a responsabilidade sobre seus riscos

    Directory of Open Access Journals (Sweden)

    Maiara Amaral dos Santos

    2006-12-01

    Full Text Available A evicção é uma figura jurídica admitida desde o direito romano. Porém a responsabilidade, diante de sua ocorrência em aquisições como a arrematação, sempre foi questão cabível de várias alterações e divergências ao longo do tempo. Geralmente atrelada aos contratos onerosos, sua ocorrência em aquisições através de hasta pública foi positivada apenas no Novo Código Civil no ordenamento jurídico brasileiro. Apesar disso, os questionamentos a respeito da atribuição de responsabilidade em tais alienações continuam admitindo diferentes entendimentos de acordo com as correntes teóricas seguidas Estas, trazem alienante, adquirente e Estado, assumindo diferentes papéis, e com base nisso imputam suas responsabilidades. Partindo das divergências apresentadas é que se propõe o presente artigo, que objetiva discutir o tema.

  11. Libros adquiridos por don Pedro Fermín de Vargas en sus viajes por las Antillas

    Directory of Open Access Journals (Sweden)

    Sergio Elías Ortíz

    1962-04-01

    Full Text Available Entre los papeles relacionados con la vida de Don Pedro Fermín de Vargas, que pueden consultarse en el Archivo General de Indias de Sevilla, hay una carta de él y una lista de libros que envía al Administrador de Correos de la Habana, Don José Fuertes, antiguo amigo suyo, luego su corresponsal y a la  vez espía de sus pasos para aprisionarlo, con el objeto de que se los guardase “en algún rincón de sus casa”.

  12. Alteraciones de la conciencia tras el daño cerebral adquirido: Una revisión sobre la anosognosia

    Directory of Open Access Journals (Sweden)

    Itsaso Colás Blanco

    2015-06-01

    Full Text Available Después de una lesión cerebral, los pacientes pueden experimentar una gran variedad de secuelas, ya sean físicas, cognitivas o emocionales. La rehabilitación neuropsicológica se encarga de proporcionar herramientas que permitan a los afectados recuperar o compensar las capacidades perdidas. Pero, ¿qué ocurre cuando la lesión impide precisamente que el paciente sea consciente de sus déficits? En el presente artículo realizamos una revisión sobre la anosognosia, destacando sus implicaciones en la rehabilitación y sus posibles mecanismos neurales.

  13. Últimas investigaciones sobre fotofobia asociada a daño cerebral adquirido y su tratamiento

    OpenAIRE

    Pardo López, Clara María

    2016-01-01

    La fotofobia se define como intolerancia dolorosa a las condiciones de luz normales. En individuos sanos la fotofobia puede existir de forma transitoria, producirse en respuesta a cualquier luz brillante o deslumbramiento y puede servir como función protectora. Sus mecanismos neurales aún son desconocidos, pero hay muchos factores que se sabe que causan fotofobia patológica, los cuales suelen estar asociados con anormalidad en cualquier lugar o estructura de la vía visual, desde la película l...

  14. Recovery of the heavy elements by NaY AND NaZSM-5 sorbant materials

    International Nuclear Information System (INIS)

    Nibou, D.; Lebail, S.

    1997-04-01

    Porous sorbants as zeolites have a several applications in differents fiels: industrial gas purification, catalysis, transformation hydrocarbures prosesses and exchange ions. The hiogh capacity to exchange their cations with those of aqueous solutions was known (1). Since the accession of synthetic zeolites, these silicates have invaded the market and the firstindustrial applications were in exchange field. Studies at Battelle Northwest in Rchland, Washington have shown that zeolites may be used in treatment of radioactive wastes (2). The used method for storing the isotopes is based on selective removal by ion exchange. Clinoptilolite, zeolite (modernite), NaA, and AW-500 have been used. In this context, the present work deals with the recovery of heavy metals like lead and uranium using some microporous materials. The obtained results show that NaY faujasite and NaZSM-5 of the FAU- and MFI-type structure respectively are very effective in removing these elements from waste water

  15. Reaction of metal oxides with molten mixtures NaPO3+NaCl

    International Nuclear Information System (INIS)

    Kovarskaya, E.N.; Mityakhina, V.S.; Rodionov, Yu.I.; Silin, M.Yu.

    1988-01-01

    By methods of solubility determination and paper chromatography it is shown, that Fe 2 O 3 solution in NaPO 3 +NaCl melts in the air relizes due to its chemical interaction with solvent resulting in formation of iron and sodium binary di- and monophosphates depending on melt-solvent initial composition, its attainment of equilibrium state and experiment temperature. It is established, that oxides increased solubility in melts with NaCl initial content ∼30 mol.% is specified by sodium tri- and tricyclophosphates presence in the melts. On this basis of NGR-spectroscopy data the presence of iron, europium, tin and sodium binary di- and monophosphates in some chloride-polyphosphate melts is confirmed

  16. NA48 experiment : view along the NA48 beamline with the detector in the distance.

    CERN Multimedia

    Hans Taureg

    1996-01-01

    Photo 02: Side view of the NA48 experiment showing the LKR calorimeter cryostat No one is sure why the Universe wound up the way it has: all matter and no antimatter. According to prevailing theories, the early universe had equal amounts of matter and antimatter. To see what might be missing from the theories, physicists search for the rare cases in which matter and antimatter behave differently. One such imbalance, called direct CP violation, showed up in the NA 31 experiment at CERN. The results from this experiment, first presented in 1993, showed that when K mesons and their antimatter cousins decay, they show a slight preference for matter over antimatter. Later experiments with neutral K mesons, including NA48 at CERN and KTeV at Fermilab in the United States, showed direct CP violation is real.

  17. Erythrocyte Na+/K+ ATPase activity measured with sup 23 Na NMR

    Energy Technology Data Exchange (ETDEWEB)

    Ouwerkerk, R.; van Echteld, C.J.; Staal, G.E.; Rijksen, G. (University Hospital, Utrecht (Netherland))

    1989-11-01

    A {sup 23}Na NMR assay for measurement of erythrocyte Na+/K+ ATPase activity is presented. Using the nonpermeant shift reagent dysprosium tripolyphosphate the signals of intra- and extracellular sodium are separated, enabling measurement of sodium fluxes nondestructively, without the need to physically separate the cells from their environment. By increasing membrane permeability with nystatin we have shown that the assay allows the detection of differences in membrane permeability. With low doses of nystatin the ouabain-sensitive sodium flux increased more than twofold. With high doses of nystatin the Na+/K+ pump could not prevent an almost total equilibration of intra- and extracellular sodium. All sodium that entered the cells remained NMR visible, proving that sodium influx can be measured quantitatively. {sup 31}P NMR spectra taken before and after the assay revealed a slight acidification of the cells and no significant change in ATP concentration. No evidence of Dy3+ entering the cell was observed.

  18. Energy levels of the single excited states in NaI and Na-like ions

    International Nuclear Information System (INIS)

    El-Sherbini, T.M.; Wahby, A.S.

    1987-08-01

    Energy levels of the single excited 1s 2 2s 2 2p 6 ns( 2 S), 1s 2 2s 2 2p 6 mp( 2 P), 1s 2 2s 2 2p 6 md( 2 D) and 1s 2 2s 2 2p 6 nf( 2 F); n=4-7, m=3-6 states for NaI and Na-like ions are calculated using the one configuration Hartree-Fock method. Good agreement is obtained between our results for the higher members of the NaI sequence and previous data from photo-absorption and beam foil experiments. (author). 11 refs, 3 figs, 9 tabs

  19. Na+-K+ pump in chronic renal failure

    International Nuclear Information System (INIS)

    Deepak, K.; Kahn, T.

    1987-01-01

    This review summarizes the evidence for the defect in Na + -K + pump in chronic renal failure, considers the role of various factors in causing this defect, and discusses the clinical implications thereof. Intracellular Na is elevated in erythrocytes, leukocytes, and muscle cells from some patients with chronic renal failure (CRF). Recent evidence suggest that this elevation of cell Na may be, in large part, a consequence of decreased number of Na + -K + pump units per cell. Maintenance dialysis over a period of weeks ameliorates the defect in intracellular Na + , and this improvement is contemporaneous with an increase in the number of Na + -K + pump sites per cell. In erythrocytes with normal cell Na + , acute hemodialysis increases the rate of 22 Na + and 42 K + transport. Many factors such as the presence of retained toxic metabolite or circulating inhibitor in the uremic plasma, or biochemical changes produced by acute hemodialysis, may explain this finding. In cells with high cell Na + , the pump-mediated 42 K + transport is normalized at the expense of a raised cell Na + . The decreased muscle membrane potential in uremic subjects has been attributed to a decreased activity of Na + -K + pump. The authors discuss the role of hormonal abnormalities and circulating inhibitors, which may cause an acute inhibition of the pump and of other factors such as K + depletion, which may cause more chronic alterations. The implications of alteration of Na + and K + pump transport and raised cell Na + on other non-pump-mediated transport pathways are discussed. Raised cell Na + may be a marker for the adequacy of maintenance dialysis in patients with end-stage renal failure

  20. Izdelovalci glasbil na Slovenskem 1606–1918

    Directory of Open Access Journals (Sweden)

    Darja Koter

    2003-12-01

    Full Text Available Proučevanje zgodovine izdelovanja inštrumentov in posameznih izdelovalcev na Slovenskem nima dolge tradicije. Na ta del glasbene preteklosti je strokovno in drugo javnost prvi opozoril Josip Mantuani ob 60-letnici ljubljanske Glasbene matice leta 1932, ki je ob tej priložnosti v Narodnem domu v Ljubljani organizirala veliko razstavo Razvoj glasbe pri Slovencih, kjer so bili z izdelki predstavljeni tudi nekateri starejši in sodobni domači izdelovalci inštrumentov. Med najmanj razvitimi segmenti muzikologije na Slovenskem sta organologija glasbenih inštrumentov in zgodovina izdelovanja glasbil. Večje strokovne pozornosti so bile deležne predvsem orgle in orglarji. Orglarstvo in posamezne mojstre so od sedemdesetih let naprej proučevali Ladislav Šaban, Milko Bizjak in Edo Škulj, v zadnjem desetletju pa se stopnjuje zanimanje še za izdelovalce drugih inštrumentov, ki so v preteklih stoletjih delovali na ozemlju današnje Slovenije. Rezultati posameznih študij so objavljeni v različnih publikacijah, revijah, zbornikih in leksikonih, nekaj podatkov o izdelovalcih pa najdemo tudi v tuji literaturi. Da bi bilo poznavanje zgodovine izdelovanja glasbil in posameznih mojstrov bolj pregledno in dostopnejše, je nujno, da objavljene dosežke strnemo v obliki gesel z vsemi najbolj vitalnimi podatki, s čimer bodo imeli uporabniki boljši dostop do informacij. Pri oblikovanju gesel je bila upoštevana metodologija, ki se je uveljavila v nemški in angleški leksikografski literaturi. Imena izdelovalcev so zapisana v izvirni obliki, ponekod pa so dodane še različice priimkov in imen, ki jih najdemo v primarnih virih. Pri rojstnih podatkih so navedene letnice rojstva in smrti ter natančni datumi, kadar so znani. V primerih, kjer čas rojstva ni ugotovljen, so pomembne letnice delovanja posameznika. Primer: CAJHEN, (Zeichen, Martin (1855–1863. Pri poklicu je mogočih več navedb, npr. izdelovalec orgel, organist, trgovec z glasbili ... Kadar

  1. A metodologia de projecto na aprendizagem da biodiversidade e geodiversidade na praia da concha

    OpenAIRE

    Rosa, Marina Maria Filipe

    2012-01-01

    Dissertação de mestrado em Biologia e de Geologia, apresentada ao Departamento de Ciências da Terra e ao Departamento de Ciências da Vida Este trabalho consistiu na implementação e avaliação da metodologia de projeto no estudo da Biodiversidade e Geodiversidade na Praia da Concha, Portugal Central, dando ênfase ao trabalho prático, através de uma aula de campo e de aulas laboratoriais. O trabalho foi realizado numa escola da Marinha Grande, com 11 alunos do 10º ano de escolaridade. Sendo a...

  2. Velocity distribution and dimer formation in a Na/Na2 beam

    International Nuclear Information System (INIS)

    Bergmann, K.; Hefter, U.; Hering, P.

    1977-01-01

    Using the TOF via optical pumping method and the Doppler-shifted laser induced emission described previously, the authors have measured the parallel and perpendicular velocity distribution respectively for Na atoms and Na 2 molecules in a variety of individual quantum states. In addition they monitored the flux of molecules in specific states while changing the stagnation pressure. In all cases a significant dependence on the internal energy of the molecules was found. The goal of these experiments is to improve understanding of the beam dynamics and the dimer formation process. (Auth.)

  3. OGLAŠEVANJE NA SOCIALNEM OMREŽJU FACEBOOK, NA PRIMERU SPLETICNA.SI

    OpenAIRE

    Reisman, Nina

    2011-01-01

    Internet je od svojega razvoja dolgo časa obstajal kot prostor za enostransko komunikacijo. Isto se je dogajalo na televiziji, radiu in časopisih, kjer je javnost sprejemala informacije, ki jih je nekdo pripravil. Tradicionalni mediji so hitro doumeli, da takšna vrsta komunikacije ni naravna in ne predstavlja najboljšega ohranjanja gledalcev in poslušalcev. Začela se je uporabljati dvosmerna komunikacija. Trenutno v svetu najbolje poznan primer dvosmerne komunikacije je socialno omrežje F...

  4. Design and implementation of the NaI(Tl)/CsI(Na) detectors output signal generator

    International Nuclear Information System (INIS)

    Zhou Xu; Liu Congzhan; Zhao Jianling

    2014-01-01

    We designed and implemented a signal generator that can simulate the output of the NaI(Tl)/CsI(Na) detectors' pre-amplifier onboard the Hard X-ray Modulation Telescope (HXMT). Using the development of the FPGA (Field Programmable Gate Array) with VHDL language and adding a random constituent, we have finally produced the double exponential random pulse signal generator. The statistical distribution of the signal amplitude is programmable. The occurrence time intervals of the adjacent signals contain negative exponential distribution statistically. (authors)

  5. Design and implementation of the NaI(Tl)/CsI(Na) detectors output signal generator

    Science.gov (United States)

    Zhou, Xu; Liu, Cong-Zhan; Zhao, Jian-Ling; Zhang, Fei; Zhang, Yi-Fei; Li, Zheng-Wei; Zhang, Shuo; Li, Xu-Fang; Lu, Xue-Feng; Xu, Zhen-Ling; Lu, Fang-Jun

    2014-02-01

    We designed and implemented a signal generator that can simulate the output of the NaI(Tl)/CsI(Na) detectors' pre-amplifier onboard the Hard X-ray Modulation Telescope (HXMT). Using the development of the FPGA (Field Programmable Gate Array) with VHDL language and adding a random constituent, we have finally produced the double exponential random pulse signal generator. The statistical distribution of the signal amplitude is programmable. The occurrence time intervals of the adjacent signals contain negative exponential distribution statistically.

  6. Subnitride chemistry: A first-principles study of the NaBa3N, Na5Ba3N, and Na16Ba6N phases

    International Nuclear Information System (INIS)

    Oliva, Josep M.

    2005-01-01

    An ab initio study on the electronic structure of the subnitrides NaBa 3 N, Na 5 Ba 3 N, and Na 16 Ba 6 N is performed for the first time. The NaBa 3 N and Na 5 Ba 3 N phases consist of infinite 1 ∞ [NBa 6/2 ] strands composed of face-sharing NBa 6 octahedra surrounded by a 'sea' of sodium atoms. The Na 16 Ba 6 N phase consist of discrete [NBa 6 ] octahedra arranged in a body-cubic fashion, surrounded by a 'sea' of sodium atoms. Our calculations suggest that the title subnitrides are metals. Analysis of the electronic structure shows partial interaction of N(2s) with Ba(5p) electrons in the lower energy region for NaBa 3 N and Na 5 Ba 3 N. However, no dispersion is observed for the N(2s) and Ba(5p) bands in the cubic phase Na 16 Ba 6 N. The metallic band below the Fermi level shows a strong mixing of N(2p), Ba(6s), Ba(5d), Ba(6p), Na(3s) and Na(3p) orbitals. The metallic character in these nitrides stems from delocalized electrons corresponding to hybridized 5d l 6s m 6p n barium orbitals which interact with hybridized 3s n 3p m sodium orbitals. Analysis of the electron density and electronic structure in these nitrides shows two different regions: a metallic matrix corresponding to the sodium atoms and the regions around them and heteropolar bonding between nitrogen and barium within the infinite 1 ∞ [NBa 6/2 ] strands of the NaBa 3 N and Na 5 Ba 3 N phases, and within the isolated [NBa 6 ] octahedra of the Na 16 Ba 6 N phase. The nitrogen atoms inside the strands and octahedra are negatively charged, the anionic character of nitrogens being larger in the isolated octahedra of the cubic phase Na 16 Ba 6 N, due to the lack of electron delocalization along one direction as opposed to the other phases. The sodium and barium atoms appear to be slightly negatively and positively charged, the latter to a larger extent. From the computed Ba-N overlap populations as well as the analysis of the contour maps of differences between total density and superposition of

  7. NaI(Tl) response functions

    Energy Technology Data Exchange (ETDEWEB)

    Vega C, H. R.; Ortiz R, J. M. [Universidad Autonoma de Zacatecas, Unidad Academica de Estudios Nucleares, Cipres No. 10, Fracc. La Penuela, 98068 Zacatecas, Zac. (Mexico); Benites R, J. L. [Centro Estatal de Cancerologia de Nayarit, Calz. de la Cruz 118 Sur, Tepic, Nayarit (Mexico); De Leon M, H. A., E-mail: fermineutron@yahoo.com.mx [Instituto Tecnologico de Aguascalientes, Av. Adolfo Lopez Mateos 1801 Ote., 20155 Aguascalientes, Ags. (Mexico)

    2015-09-15

    The response functions of a NaI(Tl) detector have been estimated using Monte Carlo methods. Response functions were calculated for monoenergetic photon sources (0.05 to 3 MeV). Responses were calculated for point-like sources and for sources distributed in Portland cement cylinders. The responses were used to calculate the efficiency functions in term of photon energy. Commonly, sources used for calibration are point-like, and eventually sources to be measured have different features. In order to use the calibrated sources corrections due to solid angle, self-absorption and scattering, must be carried out. However, some of these corrections are not easy to perform. In this work, the calculated responses were used to estimate the detector efficiency of point-like sources, and sources distributed in Portland type cement. Samples of Portland paste were prepared and were exposed to photoneutrons produced by a 15 MV linac. Some of the elements in the cement were activated producing γ-emitting radionuclides that were measured with a NaI(Tl) gamma-ray spectrometer, that was calibrated with point-like sources. In order to determine the specific activity in the induced radioisotopes calculated efficiencies were used to make corrections due to the differences between the solid angle, photon absorption and photon scattering in the point-like calibration sources and the sources distributed in cement. During the interaction between photoneutrons and the cement samples three radioisotopes were induced: {sup 56}Mn, {sup 24}Na, and {sup 28}Al. (Author)

  8. Teratological studies of DTPA-CaNa3, DTPA-ZnNa3 and quinamic acid in mice

    International Nuclear Information System (INIS)

    Luo Meichu; Ruan Tianming; Tong Shungao

    1989-01-01

    DTPA-CaNa 3 , DTPA-ZnNa 3 and quinamic acid are effective chelating agents for removing actinide elements from the body. In this experiment, different doses of DTPA-CaNa 3 , DTPA-ZnNa 3 and quinamic acid were given to mice on gestation days 6-10. Eight groups of mice received 0.8 and 2.0 mM/kg of DTPA-CaNa 3 , 3.8, 7.6, and 11.4 mM/kg of DTPA-ZnNa 3 and 0.42, 2.1, and 4.2 mM/kg of quinamic acid. Hypetonic saline and isotonic saline were given to two control groups. DTPA-CaNa 3 and quinamidic acid were found to be much more toxic to fetus of mice than DTPA-ZnNa 3 . When the doses of DTPA-CaMa 3 and quinamidic acid were 20 times higher than the human dose, the number of resorbed fetus was increased and the number and weight of live fetus were reduced. The result of injection with 7.6 mM/kg (200 times of human dose)DTPA-ZnNa 3 and that of injection with isotonic saline are the same. Therefore, we suggest that the DTPA-CaNa 3 and quinamidic acid should not be given to pregnant woman, if chelation therapy is needed, while the much safer DTPA-ZnNa 3 could be used

  9. Results on leptonic probes from NA50

    CERN Document Server

    Alessandro, B; Arnaldi, R; Atayan, M; Baglin, C; Baldit, A; Bedjidian, Marc; Beolè, S; Boldea, V; Bordalo, P; Borenstein, S R; Borges, G; Bussière, A; Capelli, L; Castanier, C; Castor, J I; Chaurand, B; Cheynis, B; Chiavassa, E; Cicalò, C; Claudino, T; Comets, M P; Constantinescu, S; Cortese, P; Cruz, J; De Falco, A; De Marco, N; Dellacasa, G; Devaux, A; Dita, S; Drapier, O; Espagnon, B; Fargeix, J; Force, P; Gallio, M; Gavrilov, Yu K; Gerschel, C; Giubellino, P; Golubeva, M B; Gonin, M; Grigorian, A A; Grigorian, S; Grossiord, J Y; Guber, F F; Guichard, A; Gulkanian, H R; Hakobyan, R S; Haroutunian, R; Idzik, M; Jouan, D; Karavitcheva, T L; Kluberg, L; Kurepin, A B; Le Bornec, Y; Lourenço, C; Macciotta, P; MacCormick, M; Marzari-Chiesa, A; Masera, M; Masoni, A; Monteno, M; Musso, A; Petiau, P; Piccotti, A; Pizzi, J R; Prado da Silva, W L; Prino, F; Puddu, G; Quintans, C; Ramello, L; Ramos, S; Rato-Mendes, P; Riccati, L; Romana, A; Santos, H; Saturnini, P; Scalas, E; Scomparin, E; Serci, S; Shahoyan, R; Sigaudo, F; Sitta, M; Sonderegger, P; Tarrago, X; Topilskaya, N S; Usai, G L; Vercellin, Ermanno; Villatte, L; Willis, N; Wu, T

    2003-01-01

    The NA50 Collaboration has performed a new measurement of the J/ psi yield in Pb-Pb collisions at 158 GeV/nucleon in improved experimental conditions. Our preliminary analysis of the year 2000 data sample, while confirming the onset of anomalous suppression and the non saturation of the J/ psi /Drell-Yan cross-section ratio, shows that peripheral Pb-Pb interactions follow the normal nuclear absorption pattern, which has in turn been established more precisely thanks to high statistics p-A data. (11 refs).

  10. Disfonia na criança

    OpenAIRE

    Marta, Diana Simões

    2017-01-01

    Trabalho Final do Curso de Mestrado Integrado em Medicina, Faculdade de Medicina, Universidade de Lisboa, 2017 Disfonia é um termo clínico que se refere a todas as alterações e dificuldades na emissão vocal que impedem a produção normal da voz. É um sintoma frequente em idade pediátrica com consequências negativas em vários aspetos da vida da criança. Este artigo tem como objetivo resumir o conhecimento atual sobre a definição, epidemiologia, etiologia, características clínicas, abordag...

  11. Skate na cidade, imagens da cidade

    OpenAIRE

    Machado, Giancarlo Marques Carraro

    2014-01-01

    Apesar da existência de dezenas de pistas de skate na cidade de São Paulo – espaços considerados “próprios” para o skate -, a maioria dos skatistas da modalidade street skate confere maior importância à prática feita nas ruas, onde, para muitos, se “anda de skate de verdade”. A atração que elas exercem é a possibilidade de encontrar diferentes tipos de picos, ou seja, equipamentos urbanos (bancos, corrimãos, escadas, canteiros) obstáculos onde se realizam as manobras. Este artigo busca analis...

  12. The NA62 experiment at CERN

    International Nuclear Information System (INIS)

    Piccini, Mauro

    2016-01-01

    The rare decays K → πvv-bar are excellent processes to make tests of new physics at the highest scale complementary to LHC thanks to their theoretically cleanness. The NA62 experiment at CERN SPS aims to collect of the order of 100 events in two years of data taking for the decay K"+ → π"+vv-bar, keeping the background at the level of 10%. Part of the experimental apparatus has been commissioned during a technical run in 2012. The diverse and innovative experimental techniques will be explained and some preliminary results obtained during the 2014 pilot run will be reviewed

  13. Cerenkov counter for the experiment NA3

    CERN Multimedia

    1978-01-01

    The program of the NA3 experiment included the study of hadronic interactions with a large transverse momentum pT, thus the inclusion in the set-up of three gas threshold Cerenkov counters of large acceptance. The photo shows the downstream part of the second Cerenkov (located at the output of the magnet). The yellow membrane is a temporary protection for the optics (shown in photo 7810540X) to be taken away when fixing this part to the gas tank (entering the magnet and not shown). The photomultipliers all around are heavily shielded.

  14. Na(+),K (+)-ATPase as a docking station: protein-protein complexes of the Na(+),K (+)-ATPase.

    Science.gov (United States)

    Reinhard, Linda; Tidow, Henning; Clausen, Michael J; Nissen, Poul

    2013-01-01

    The Na(+),K(+)-ATPase, or sodium pump, is well known for its role in ion transport across the plasma membrane of animal cells. It carries out the transport of Na(+) ions out of the cell and of K(+) ions into the cell and thus maintains electrolyte and fluid balance. In addition to the fundamental ion-pumping function of the Na(+),K(+)-ATPase, recent work has suggested additional roles for Na(+),K(+)-ATPase in signal transduction and biomembrane structure. Several signaling pathways have been found to involve Na(+),K(+)-ATPase, which serves as a docking station for a fast-growing number of protein interaction partners. In this review, we focus on Na(+),K(+)-ATPase as a signal transducer, but also briefly discuss other Na(+),K(+)-ATPase protein-protein interactions, providing a comprehensive overview of the diverse signaling functions ascribed to this well-known enzyme.

  15. Effect of growth in lithium on ouabain binding, Na-K-ATPase and Na and K transport in hela cells.

    Science.gov (United States)

    Boardman, L J; Hume, S P; Lamb, J F; Polson, J

    1975-01-01

    1. HeLa cells were grown for 24 hr in growth medium in which part of the Na was replaced with Li. Ion contents, cell volumes and numbers, Na-K-ATPase and specific ouabain binding were measured. In some experiments the Na efflux and net Na transport was also measured. 2. Growth in Li caused a rise in the specific ouabain binding and membrane Na-K-ATPase of these cells. The Li concentrations in the cells necessary to produce this effect ranged up to 50 mM. 3. It is suggested that Li, like Na, acts on the genetic material of the cells to cause the production of more Na pumps within the membrane. PMID:124350

  16. The relation between aging, aortic NaF avidity and coronary artery NaF avidity: A NaF PET CT study

    DEFF Research Database (Denmark)

    Blomberg, Björn; Thomassen, Anders; Hildebrandt, Malene

    2013-01-01

    volunteers without traditional cardiovascular risk factors were prospectively assessed by Sodium 18-Fluoride (Na-18F) PET CT imaging. Global aortic uptake of Na-18F was determined by calculating the average aortic blood pool subtracted maximum standardized uptake value (cSUV) [maximum SUVaorta - mean...

  17. Minimizing Load Effects on NA4 Gear Vibration Diagnostic Parameter

    Science.gov (United States)

    Dempsey, Paula J.; Zakrajsek, James J.

    2001-01-01

    NA4 is a vibration diagnostic parameter, developed by researchers at NASA Glenn Research Center, for health monitoring of gears in helicopter transmissions. The NA4 reacts to the onset of gear pitting damage and continues to react to the damage as it spreads. This research also indicates NA4 reacts similarly to load variations. The sensitivity of NA4 to load changes will substantially affect its performance on a helicopter gearbox that experiences continuously changing load throughout its flight regimes. The parameter NA4 has been used to monitor gear fatigue tests at constant load. At constant load, NA4 effectively detects the onset of pitting damage and tracks damage severity. Previous research also shows that NA4 reacts to changes in load applied to the gears in the same way it reacts to the onset of pitting damage. The method used to calculate NA4 was modified to minimize these load effects. The modified NA4 parameter was applied to four sets of experimental data. Results indicate the modified NA4 is no longer sensitive to load changes, but remains sensitive to pitting damage.

  18. Advancement of technology towards developing Na-ion batteries

    Science.gov (United States)

    Jamesh, Mohammed Ibrahim; Prakash, A. S.

    2018-02-01

    The Na-ion-batteries are considered much attention for the next-generation power-sources due to the high abundance of Na resources that lower the cost and become the alternative for the state of the art Li-ion batteries in future. In this review, the recently reported potential cathode and anode candidates for Na-ion-batteries are identified in-light-of-their high-performance for the development of Na-ion-full-cells. Further, the recent-progress on the Na-ion full-cells including the strategies used to improve the high cycling-performance (stable even up-to 50000 cycles), operating voltage (even ≥ 3.7 V), capacity (>350 mAhg-1 even at 1000 mAg-1 (based-on-mass-of-the-anode)), and energy density (even up-to 400 Whkg-1) are reviewed. In addition, Na-ion-batteries with the electrodes containing reduced graphene oxide, and the recent developments on symmetric Na-ion-batteries are discussed. Further, this paper identifies the promising Na-ion-batteries including the strategies used to assemble full-cell using hard-carbon-anodes, Na3V2(PO4)3 cathodes, and other-electrode-materials. Then, comparison between aqueous and non-aqueous Na-ion-batteries in terms of voltage and energy density has been given. Later, various types of electrolytes used for Na-ion-batteries including aqueous, non-aqueous, ionic-liquids and solid-state electrolytes are discussed. Finally, commercial and technological-developments on Na-ion-batteries are provided. The scientific and engineering knowledge gained on Na-ion-batteries afford conceivable development for practical application in near future.

  19. Criptococose pulmonar: aspectos na tomografia computadorizada

    Directory of Open Access Journals (Sweden)

    Silva Ana Carina Gamboa da

    2003-01-01

    Full Text Available A criptococose pulmonar é uma doença causada pelo Criptococcus neoformans, um fungo unimórfico que possui distribuição mundial, existindo na mesma forma tanto no seu habitat natural quanto em animais e humanos. A doença possui apresentações clínica e patológica variáveis e pode manifestar-se tanto em pacientes com a imunidade normal como em imunocomprometidos, que representam a maioria dos casos. Neste trabalho são analisados os aspectos encontrados nas tomografias computadorizadas do tórax de 14 pacientes com criptococose pulmonar confirmada. Os achados mais freqüentes na tomografia do tórax foram as massas e os nódulos pulmonares. Outros aspectos observados foram as áreas de escavação, as consolidações, o espessamento do interstício peribroncovascular e o reticulado difuso. Massa pulmonar foi o achado isolado mais comum (64,2%, seguido dos nódulos isolados ou múltiplos (35,7%. Doença pulmonar difusa foi vista em apenas 14,2% dos casos. Os lobos superiores foram os mais comprometidos, sendo a doença mais comum nas regiões anteriores. A tomografia do tórax permitiu avaliar com precisão o grau de comprometimento do parênquima pulmonar.

  20. Vinhos, Turismo e Pluriatividade na Agricultura

    Directory of Open Access Journals (Sweden)

    Hernanda Tonini

    2013-06-01

    Full Text Available A gastronomia, além de ter importante relação com a economia, é uma forma expressiva da cultura dos indivíduos, desde o tipo de alimentos cultivados até a maneira de seu preparo e consumo. O presente artigo propõe-se a analisar a relação entre o enoturismo – centralizado na existência do vinho enquanto elemento gastronômico – e o fenômeno da pluriatividade na agricultura familiar, vista nos últimos anos como alternativa positiva para sua reprodução econômica e social. O fluxo turístico em regiões vitivinícolas gera novas oportunidades de trabalho e faz com que agricultores e suas famílias dividam a mão de obra agrícola, até então direcionada ao cultivo da uva e outros alimentos para subsistência, com atividades não agrícolas – como o artesanato, o acolhimento de visitantes em pousadas, a atuação em restaurantes, entre outras – como chance de subsistência. Este panorama transforma as realidades do mundo rural, alterando a relação do agricultor com a produção de alimentos e a forma como o mesmo os utiliza, além de reestruturar o ambiente sociocultural no seu entorno.  

  1. The NA60 experiment results and perspectives

    CERN Document Server

    Heuser, J M; Banicz, K; Borer, K; Buytaert, J; Castor, J I; Chaurand, B; Chenn, W; Cheynis, B; Cicalò, C; Colla, A; Cortese, R; David, A; De Falco, A; De Marco, N; Devaux, A; Drees, A; Ducroux, L; Enyo, H; Ferretti, A; Floris, M; Force, P; Grigorian, A A; Grossiord, J Y; Guettet, N; Guichard, A; Gulkanian, H R; Keil, M; Kluberg, L; Li, Z; Lourenço, C; Lozano-Bahilo, J; Manso, F; Masoni, A; Neves, A; Ohnishi, H; Oppedisano, C; Parracho, P; Puddu, G; Radermacher, E; Rosinsky, P; Scomparin, E; Seixas, J; Serci, S; Shahoyan, R; Sonderegger, P; Tieulent, R; Usai, G L; Vardanian, H; Veenhof, R; Wöhri, H K

    2003-01-01

    The NA60 experiment takes place at the SPS at CERN, to study the production of open charm and prompt dimuons in collisions induced by proton and heavy ion beams on nuclear targets. For this task, several novel detector systems were added to the dimuon spectrometer and zero-degree calorimeter, which were previously used in the NA50 experiment. The main upgrade is a new silicon pixel vertex spectrometer. It tracks the charged particles that are produced through the collisions in the target and allows us to match their trajectories and momenta with those of the muons that are measured behind the hadron absorber in the muon spectrometer. Besides improving considerably the dimuon mass resolution, the vertex telescope measures the offset of each muon track with respect to the interaction point. This allows us to select events where charm mesons were produced. We present in this article first results from dimuon data that were acquired in Summer 2002 with a 400 GeV proton beam. A silicon microstrip telescope was use...

  2. The NA62 GigaTracker

    CERN Document Server

    Perrin-Terrin, Mathieu

    2015-01-01

    The GigaTracker is an hybrid silicon pixel detector built for the NA62 experiment aiming at measuring the branching fraction of the ultra-rare kaon decay K + ! p + n ̄ n at the CERN SPS. The detector has to track particles in a beam with a flux reaching 1.3 MHz/mm 2 and provide single-hit timing with 200ps RMS resolution for a total material budget of less than 1.5 X 0 . The tracker comprises three 60.8mm 27mm stations installed in vacuum ( 10$^{-6}$ mbar) and cooled with liquid C 6 F 14 circulating through micro-channels etched inside few hundred of microns thick silicon plates. Each station is composed of a 200 m m thick silicon sensor readout by 2 x 5 cus- tom 100 m m thick ASIC, called TDCPix. Each chip contains 40 x 45 asynchronous pixels, each 300 m m x 300 m m and is instrumented with 100ps bin time-to-digital converters. In order to cope with the high rate, the TDCPix is equipped with four 3.2Gb/s serialisers sending out the data. We will describe the detector and the results from the 2014 NA62 ru...

  3. Status for 2018, CERN NA63

    CERN Document Server

    Nielsen, CF; Di Piazza, A; Wistisen, TN

    2018-01-01

    In the NA63 experiment of April 2018 the purpose was to look for the effect of the derivative term, the so-called Schott-term, in classical radiation reaction as described in \\cite{DiPiazza20171}. Data was taken for 20, 40 and 80 GeV electrons and positrons aligned to the $\\langle100\\rangle$ axis of a diamond crystal of thickness 1.5 mm, as well as for 40 and 80 GeV electrons on a 1.0 mm thick diamond aligned to the $\\langle100\\rangle$ axis. The data which was taken during the run shows encouraging results, but await a thorough analysis. For the 2017 data, the analysis is still ongoing, but expected to be finished within the coming few months. The results look very promising, but no final conclusion can be drawn at the present stage. For the 2016 results on quantum radiation reaction obtained by CERN NA63, the results have been published in Nature Communications \\cite{Wist17}.

  4. Direito do poeta na literatura de cordel

    Directory of Open Access Journals (Sweden)

    Sale Mário Gaudêncio

    Full Text Available Este artigo apresenta uma análise situacional dos direitos autorais na literatura de cordel, especialmente no que se refere à proteção moral e patrimonial que é dada aos poetas populares. Justifica-se o estudo em função de não haver profundas nem atuais discussões teóricas sobre a preservação moral e patrimonial em torno das obras de cordel. Utiliza-se como metodologia a pesquisa bibliográfica relacionada a um corpusque analisa os folhetos impressos por poetas da literatura de cordel. O estudo mostra como resultados o estabelecimento de um modelo alternativo de prazos para os direitos autorais na poesia popular, além da necessidade de ruptura técnica, política e cultural. Conclui informando sobre a importância de se construir um banco de dados nacional para que se tenha conhecimento pleno do quê e como se está produzindo a literatura de cordel, além de saber quem verdadeiramente está sendo beneficiado com tais produções.

  5. Plantas indicadoras de clomazone na fase vapor

    Directory of Open Access Journals (Sweden)

    Fábio Schreiber

    2013-10-01

    Full Text Available A volatilização representa um processo importante no deslocamento de agrotóxicos para o ambiente. As características físico-químicas da molécula do clomazone indicam que este possui potencial de volatilização. Em vista do exposto, para a realização deste estudo, foram conduzidos dois experimentos com o objetivo de avaliar a suscetibilidade das espécies: pepino, melão, milho, sorgo e arroz a diferentes formulações do herbicida clomazone na fase vapor. Para isso, foram utilizadas caixas de vidro hermeticamente fechadas, com a presença de diferentes formulações de clomazone e as espécies vegetais. As formulações utilizadas foram Gamit 360 CS®, Gamit 500 EC® e Gamit Star®. Com os resultados obtidos, foi possível concluir que, dentre as espécies avaliadas, independente da formulação utilizada, a de menor tolerância ao herbicida clomazone na fase vapor foi o sorgo, seguido do milho e do arroz.

  6. A biotecnologia na agropecuária

    Directory of Open Access Journals (Sweden)

    João Lúcio de Azevedo

    1986-11-01

    Full Text Available This review reports the use of biotechnology in agriculture and animal husbandry. The main techniques and the most important products both in experimental stage or in commercial use are reported. The work intends to give a global vision to the theme, chronologically and spacely, showing the main lines of research and what has been obtained in this area. The techniques and products that are related to genetics and breeding are emphasized. Revisão Bibliográfica do emprego da biotecnologia na agropecuária, mostrando um levantamento das técnicas mais promissoras e de seus principais produtos, tanto em fase experimental como em uso comercial. Pretende-se dar uma visão global do assunto, cronológica e espacialmente, não se prendendo à detalhes, mostrando, em Unhas gerais, o que foi feito e o que se faz, atualmente, em biotecnologia. As técnicas e produtos que influenciam a área de genética e melhoramento genético na agropecuária, são enfatizadas.

  7. Mercosul educativo na carreira de Enfermagem

    Directory of Open Access Journals (Sweden)

    Roseli Schmoeller

    2012-10-01

    Full Text Available O Mercosul, instituído com vistas à integração econômica, política, social e cultural entre os países membros, atualmente destaca-se pelas estratégias integrativas de âmbito educacional. Este artigo aborda os movimentos acerca da formação acadêmica dos cursos de Enfermagem e o trajeto histórico de integração educacional, apresentando o Sistema de Acreditação dos Cursos Universitários do Mercosul, o ARCU-SUL, além dos setores responsáveis por esse processo e as perspectivas para a Enfermagem nos países do Mercosul. Entendemos que para o desenvolvimento de profissionais críticos, reflexivos e com compromisso político-social, é fundamental investir na formação e na qualidade dos centros de ensino em Enfermagem.

  8. Mechanochemical transformations in Li(Na)AlH4-Li(Na)NH2 systems

    International Nuclear Information System (INIS)

    Dolotko, Oleksandr; Zhang Haiqiao; Ugurlu, Ozan; Wiench, Jerzy W.; Pruski, Marek; Scott Chumbley, L.; Pecharsky, Vitalij

    2007-01-01

    Mechanochemical transformations of tetrahydroaluminates and amides of lithium and sodium have been investigated using gas volumetric analysis, X-ray powder diffraction, solid-state nuclear magnetic resonance (NMR) and transmission electron microscopy. In a transformation of LiAlH 4 and LiNH 2 taken in an 1:1 molar ratio, the amount of released hydrogen (6.6 wt.% after 30 min ball milling) was higher than in any known one pot mechanochemical process involving a hydrogen-containing solid. A total of 4.3 wt.% of hydrogen is released by the NaAlH 4 -NaNH 2 system after 60 min ball milling; and 5.2 wt.% H 2 is released when LiAlH 4 and NaNH 2 or NaAlH 4 and LiNH 2 are ball milled for 90 min and 120 min, respectively. All transformations proceed at room temperature. The mechanism of the overall transformation MAlH 4 (s) + MNH 2 (s) → 2MH(s) + AlN(s) + 2H 2 (g) was identified based on detailed spectroscopic analysis of the intermediate (M 3 AlH 6 ) and final products of the ball milling process

  9. Aspectos valorizados por porfissionais de enfermagem na higiene pessoal e na higiene corporal do paciente

    Directory of Open Access Journals (Sweden)

    Elóide André Oliveira

    2003-10-01

    Full Text Available Survey descritivo, com o qual se objetivou identificar que aspectos da higiene corporal são valorizados pelos componentes da equipe de enfermagem, na higiene corporal pessoal e na higiene corporal do paciente. A pesquisa foi desenvolvida em oito instituições públicas de saúde e a amostra foi composta por 126 profissionais de enfermagem, correspondendo a 12,8% do total de 986 componentes das equipes de enfermagem destas instituições. Na higiene corporal pessoal, chamou a atenção o fato de que os cuidados com as unhas e com os cabelos tenham suplantado, no número de citações dos profissionais de enfermagem, aspectos básicos como o cuidado com as mãos. Na higiene corporal do paciente, o banho foi o aspecto considerado mais importante pelas três categorias profissionais; a higiene oral, pelas(os enfermeiras(os e auxiliares de enfermagem; e as unhas, pelas(os enfermeiras(os e técnicas(os de enfermagem.

  10. Excess Enthalpies of Mixing of Binary Mixtures of NaCl, KCl, NaBr ...

    African Journals Online (AJOL)

    NJD

    2004-07-01

    Jul 1, 2004 ... NaBr and KBr in Mixed Ternary Solvent Systems at 298.15 K. Bal Raj Deshwala* ... industrial waters and their thermodynamic properties are of practical interest for .... The enthalpy of mixing (∆Hm) is the difference between the excess enthalpy of the ..... tural (categorized by softness, open- ness, and ...

  11. Efeito do plasma de oxigênio na dentina previamente exposta ao NaOCl

    Directory of Open Access Journals (Sweden)

    Maíra do PRADO

    Full Text Available Resumo Introdução O tratamento de plasma é uma tecnologia eficaz que pode manter as propriedades internas dos materiais inalteradas após o tratamento, modificando apenas a superfície. Objetivo Avaliar o efeito do plasma de oxigênio na dentina previamente exposta ao NaOCl 6%. Material e método Foram utilizados 60 incisivos bovinos. A coroa foi removida, a raiz foi dividida e as faces planificadas, totalizando 120 segmentos referentes ao terço cervical. As amostras foram divididas em dois grupos: controle (imersa em NaOCl 6%, lavada com água destilada, seca, imersa em EDTA 17%, lavada e seca e plasma de oxigênio (após tratamento descrito no grupo controle, plasma de oxigênio foi aplicado por 30 s. As amostras foram avaliadas qualitativamente em relação à topografia por microscopia eletrônica de varredura, utilizando-se microfotografias com ampliação de 1.000×. O goniômetro Ramé-hart foi utilizado para a mensuração do ângulo de contato entre as superfícies e as seguintes soluções foram utilizadas: água, etilenoglicol e di-iodometano. Em seguida, a energia de superfície, representada pelas componentes polar e dispersiva, foi calculada. Avaliou-se também o escoamento dos cimentos Pulp Canal Sealer EWT (PCS e Real Sal SE (RS na superfície dentinária. Os dados foram analisados estatisticamente utilizando os testes Kruskal-Wallis e Mann-Whitney U (p<0,05. Resultado O tratamento com plasma levou à formação de uma camada semelhante à smear layer na superfície dentinária. Este tratamento levou a um aumento da energia de superfície e da componente polar, favorecendo a hidrofilicidade da superfície. Entretanto, desfavoreceu o escoamento do cimento PCS e não influenciou no escoamento do cimento RS. Conclusão O plasma de oxigênio ocasionou mudanças topográficas na superfície dentinária, favorecendo a hidrofilicidade desta. Contudo, não favoreceu o escoamento dos cimentos endodônticos na dentina.

  12. Direitos humanos e democracia na educação infantil: atuação do psicólogo escolar em uma associação pró-educação Human rights and democracy in children's education: the role of the school psychologist at a pro-education association

    Directory of Open Access Journals (Sweden)

    Julia Chamusca Chagas

    2012-04-01

    Full Text Available A educação em/para os Direitos Humanos demanda a discussão do papel da escola na formação para a cidadania. Essa formação deve considerar a necessidade do ideal de democracia estar em todos os níveis do contexto escolar, da proposta pedagógica à organização político-administrativa. Nesta pesquisa utilizamos o conhecimento adquirido por uma experiência de atuação em psicologia escolar em uma instituição de Educação Infantil de Brasília que é uma associação de pais, professores e funcionários. O objetivo foi discutir como o psicólogo escolar participava da implementação da noção de democracia no cotidiano da escola e auxiliava a construção da coerência entre o projeto político pedagógico e as práticas educacionais voltadas para a criança. A análise dessa experiência mostrou a importância da psicologia na construção de uma educação para a democracia que trabalhe junto aos educandos não apenas o conhecimento de seus direitos, mas a aprendizagem e o desenvolvimento de práticas cidadãs.The issue of Human Rights education demands a discussion about the role of the school in developing student citizenship. This process should consider the need for the ideal of democracy to be in every level of the school context; from the pedagogical proposal to its administrative and political organization. In this research we used the knowledge obtained through an experience with school psychology at a children's education institution in Brasília that is an association of parents, teachers and employees. The goal is to discuss how the school psychologist participated in implementing the notion of democracy into the school's routine, helped building coherence between the political and pedagogical project, in addition to the educational practices involving the children. The analysis showed how important psychology is in developing a democratic education that focuses not only on teaching the students their rights, but also

  13. Stimulation of Na+/K+ ATPase activity and Na+ coupled glucose transport by β-catenin

    International Nuclear Information System (INIS)

    Sopjani, Mentor; Alesutan, Ioana; Wilmes, Jan; Dermaku-Sopjani, Miribane; Lam, Rebecca S.; Koutsouki, Evgenia; Jakupi, Muharrem; Foeller, Michael; Lang, Florian

    2010-01-01

    Research highlights: → The oncogenic transcription factor β-catenin stimulates the Na + /K + -ATPase. → β-Catenin stimulates SGLT1 dependent Na + , glucose cotransport. → The effects are independent of transcription. → β-Catenin sensitive transport may contribute to properties of proliferating cells. -- Abstract: β-Catenin is a multifunctional protein stimulating as oncogenic transcription factor several genes important for cell proliferation. β-Catenin-regulated genes include the serum- and glucocorticoid-inducible kinase SGK1, which is known to stimulate a variety of transport systems. The present study explored the possibility that β-catenin influences membrane transport. To this end, β-catenin was expressed in Xenopus oocytes with or without SGLT1 and electrogenic transport determined by dual electrode voltage clamp. As a result, expression of β-catenin significantly enhanced the ouabain-sensitive current of the endogeneous Na + /K + -ATPase. Inhibition of vesicle trafficking by brefeldin A revealed that the stimulatory effect of β-catenin on the endogenous Na + /K + -ATPase was not due to enhanced stability of the pump protein in the cell membrane. Expression of β-catenin further enhanced glucose-induced current (Ig) in SGLT1-expressing oocytes. In the absence of SGLT1 Ig was negligible irrespective of β-catenin expression. The stimulating effect of β-catenin on both Na + /K + ATPase and SGLT1 activity was observed even in the presence of actinomycin D, an inhibitor of transcription. The experiments disclose a completely novel function of β-catenin, i.e. the regulation of transport.

  14. RAZVOJ APLIKACIJE PRETOČNEGA VIDEA NA MOBILNEM TELEFONU

    OpenAIRE

    Horvat, Jernej

    2012-01-01

    Diplomsko delo obravnava prenos video signala iz mobilnega telefona na TV. Prenos poteka preko Wi-Fi omrežja. Na mobilnem telefonu je nameščena ustrezna Android aplikacija, ki omogoča direkten prenos video signala in nalaganje na TV sprejemnik. Pomemben dejavnik, ki prispeva, da je ta proces mogoč, je sistem IMS (IP multimedijski podsistem), ki predstavlja omrežja naslednje generacije.

  15. Razvoj suvremenog menadžmenta trgovine na malo

    OpenAIRE

    Segetlija, Zdenko

    2009-01-01

    Razvoj koncentracije u trgovini na malo doveo je do daljnjih promjena u njezinoj strukturi te, u skladu s tim, i do promjena u upravljanju gospodarskim subjektima u trgovini na malo. S tim u svezi mijenja se i dosadašnja paradigma marketinga trgovine na malo, budući da sve važnijim postaje oblikovanje asortimana temeljem programa category managementa i drugih oblika vertikalnoga marketinga. S druge pak strane, osim poznavanja zakonitosti razvoja novih oblika poslovnih jedinica, no...

  16. STABILIZACIJA ROBOTA NA ŽOGI IN KALMANOV FILTER

    OpenAIRE

    Turk, Janez

    2016-01-01

    Stabilizacija robota na žogi je dvodimenzionalen problem inverznega nihala (Segway). V magistrskem delu je opisana izdelava strojnega dela robota (konstrukcije in vezja), načrtovanje vseh uporabljenih algoritmov ter potek programa v digitalnem signalnem procesorju. Glavni problem, ki smo se mu najbolj posvetili, je slab podatek o nagibu, ki ga pridobimo z zlivanjem senzorskih podatkov giroskopa in pospeškometra. Za izboljšanje delovanja je še veliko rezerve pri načrtovanju regulatorjev. Poleg...

  17. Transcriptional regulators of Na, K-ATPase subunits

    OpenAIRE

    Zhiqin eLi; Sigrid A Langhans

    2015-01-01

    The Na,K-ATPase classically serves as an ion pump creating an electrochemical gradient across the plasma membrane that is essential for transepithelial transport, nutrient uptake and membrane potential. In addition, Na,K-ATPase also functions as a receptor, a signal transducer and a cell adhesion molecule. With such diverse roles, it is understandable that the Na,K-ATPase subunits, the catalytic alpha-subunit, the beta-subunit and the FXYD proteins, are controlled extensively during developme...

  18. K+ congeners that do not compromise Na+ activation of the Na+,K+-ATPase

    DEFF Research Database (Denmark)

    Mahmmoud, Yasser A; Kopec, Wojciech; Khandelia, Himanshu

    2015-01-01

    The Na(+),K(+)-ATPase is essential for ionic homeostasis in animal cells. The dephosphoenzyme contains Na(+) selective inward facing sites, whereas the phosphoenzyme contains K(+) selective outward facing sites. Under normal physiological conditions, K(+) inhibits cytoplasmic Na(+) activation...

  19. RAHNER NA BERLINDA PÓS-CONCILIAR

    Directory of Open Access Journals (Sweden)

    Luciano Campos Lavall

    2004-01-01

    Full Text Available O artigo analisa algumas críticas negativas feitas ao pensamento teológico de Karl Rahner, após sua morte, que tentam desqualificar a sua importância para a ortodoxia católica e o seu distanciamento dos fundamentos do Concílio Vaticano II. Na discussão, enfocada sobretudo no ponto de vista da eclesiologia rahneriana, retoma importante entrevista do mesmo, no ano de sua morte, na qual aparece a sua preocupação com as chances futuras da Igreja, sobretudo na Europa Ocidental, a partir da qual abordam-se as relações entre Cristianismo e Igreja. As estratégias para a organização pastoral do mundo católico são a tônica desta reflexão. Para justificar suas posturas, o artigo termina com uma avaliação global de todo o conjunto teológico de Karl Rahner, redescobrindo nele os pilares mais fundamentais que justificam sua ortodoxia a serviço da fé cristã e católica, mas também a serviço da tomada de consciência de uma fé vivenciada e comprometida por parte da humanidade marcadamente secularizada. ABSTRACT: The article analyses negative criticisms against Rahner’s theological views after his death with the intention of discrediting him and his role in Catholic orthodoxy by distancing him from the fundamentals of Vatican Council II. In the discussion, primarily focused on Rahner’s ecclesiology, the article retakes a significant interview made the same year of Rahner’s death. In this interview his concern for the Church’s future chances, especially regarding Eastern Europe, embarking on relations between Christianity and Church. The strategies for world-wide organization of Catholic ministry predominate this reflection. Justifying its postures, the article concludes with a global evaluation of Rahner’s theology, rediscovering the fundamental pillars which justify his orthodoxy at the service of the Christian and Catholic faith, but also at the service of a conscientious living of a committed faith on behalf of a notably

  20. Secretory NaCl and volume flow in renal tubules.

    Science.gov (United States)

    Beyenbach, K W

    1986-05-01

    This review attempts to give a retrospective survey of the available evidence concerning the secretion of NaCl and fluid in renal tubules of the vertebrate kidney. In the absence of glomerular filtration, epithelial secretory mechanisms, which to this date have not been elucidated, are responsible for the renal excretion of NaCl and water in aglomerular fish. However, proximal tubules isolated from glomerular fish kidneys of the flounder, killifish, and the shark also have the capacity to secrete NaCl and fluid. In shark proximal tubules, fluid secretion appears to be driven via secondary active transport of Cl. In another marine vertebrate, the sea snake, secretion of Na (presumably NaCl) and fluid is observed in freshwater-adapted and water-loaded animals. Proximal tubules of mammals can be made to secrete NaCl in vitro together with secretion of aryl acids. An epithelial cell line derived from dog kidney exhibits secondary active secretion of Cl when stimulated with catecholamines. Tubular secretion of NaCl and fluid may serve a variety of renal functions, all of which are considered here. The occurrence of NaCl and fluid secretion in glomerular proximal tubules of teleosts, elasmobranchs, and reptiles and in mammalian renal tissue cultures suggests that the genetic potential for NaCl secretion is present in every vertebrate kidney.

  1. Dejavniki psihološkega nasilja na delovnem mestu

    OpenAIRE

    Ilc, Teja

    2011-01-01

    Raziskave na področju delovnih razmer kažejo, da je danes pereč problem ravno psihološko nasilje na delovnem mestu. Posebna oblika psihološkega nasilja na delovnem mestu je mobing, s katerim se v praksi srečujemo vsak dan, vendar se ga pogosto ne zavedamo. Namen magistrske naloge je pojasniti pojem in pomen mobinga v delovnih organizacijah, poiskati možne vzroke in posledice, ki vplivajo na ta pojav, ter predlagati rešitve. Poznavanje mehanizmov, ki povzročajo mobing, njegovih vzrokov in...

  2. Angular distributions of photoelectrons from free Na clusters

    International Nuclear Information System (INIS)

    Wopperer, P.; Dinh, P. M.; Faber, B.; Reinhard, P.-G.; Suraud, E.

    2010-01-01

    We explore, from a theoretical perspective, photoelectron angular distributions (PADs) of the Na clusters Na 8 , Na 10 , Na 12 , Na 18 , Na 3 + , Na 11 + , Na 13 + , and Na 19 + . The basis of the description is the time-dependent local-density approximation (TDLDA), augmented by a self-interaction correction (SIC) to describe ionization properties correctly. The scheme is solved on a numerical grid in coordinate space with absorbing bounds. We assume for each cluster system an isotropic ensemble of free clusters and develop for the case of one-photon emission analytical formulas for computing the orientation-averaged PAD on the basis of a few TDLDA-SIC calculations for properly chosen reference orientations. It turns out that all the information in the averaged PAD is contained in one anisotropy parameter. We find that this parameter varies very little with system size, but as a whole is crucially influenced by the detailed ionic structure. We also make comparisons with direct orientation averaging and consider one example reaching outside the perturbative regime.

  3. Transcriptional regulators of Na, K-ATPase subunits

    Directory of Open Access Journals (Sweden)

    Zhiqin eLi

    2015-10-01

    Full Text Available The Na,K-ATPase classically serves as an ion pump creating an electrochemical gradient across the plasma membrane that is essential for transepithelial transport, nutrient uptake and membrane potential. In addition, Na,K-ATPase also functions as a receptor, a signal transducer and a cell adhesion molecule. With such diverse roles, it is understandable that the Na,K-ATPase subunits, the catalytic alpha-subunit, the beta-subunit and the FXYD proteins, are controlled extensively during development and to accommodate physiological needs. The spatial and temporal expression of Na,K-ATPase is partially regulated at the transcriptional level. Numerous transcription factors, hormones, growth factors, lipids and extracellular stimuli modulate the transcription of the Na,K-ATPase subunits. Moreover, epigenetic mechanisms also contribute to the regulation of Na,K-ATPase expression. With the ever growing knowledge about diseases associated with the malfunction of Na,K-ATPase, this review aims at summarizing the best-characterized transcription regulators that modulate Na,K-ATPase subunit levels. As abnormal expression of Na,K-ATPase subunits have been observed in many carcinoma, we will also discuss transcription factors that are associated with epithelial-to-mesenchymal transition, a crucial step in the progression of many tumors to malignant disease.

  4. O grotesco na imagem publicitária

    OpenAIRE

    Silva, Maria João Barros

    2013-01-01

    O significado da palavra grotesco teve um começo puramente artístico numa descoberta, de imagens de figuras humanas deformadas e alteradas. No entanto, este foi evoluindo e adotando novos significados mais amplos e concretos na atualidade. É possível encontrar vários exemplos do grotesco em várias plataformas, como no cinema, na televisão e na literatura. Neste sentido, para se poder proceder ao estudo desta temática é fundamental a conquista do conhecimento sobre o estatuto do grotesco na pu...

  5. VPLIV ULCEROZNEGA KOLITISA NA KAKOVOST ŽIVLJENJA

    OpenAIRE

    Dugi, Maja

    2015-01-01

    Pri vsaki bolezni je zelo pomembna kakovost življenja pacientov. Ulcerozni kolitis je kronična bolezen, ki je znana po obdobjih mirovanja in izbruhov, kar definitivno vpliva na posameznika, ki se s tem spopada. Sooča se z raznimi omejitvami, ki vplivajo na njegov vsakdan. Rezultati raziskave so pokazali, da je kakovost življenja bolnikov z ulceroznim kolitisom izrazito okrnjena. Ne le, da se spopadajo z bolečino, ampak tudi s psihičnimi in socialnimi posledicami, ki vplivajo na fizične aktivn...

  6. ZAZNAVA IN VPLIV BARV NA PRIMERU TISKANIH OGLASOV

    OpenAIRE

    Spes, Katja

    2015-01-01

    V diplomski nalogi smo s pomočjo literature opisali simboliko osnovnih barv, vpliv, ki ga imajo na ljudi, ter njihov pomen v oglasnih sporočilih. Omejili smo se na tiskane oglase (plakate, časopise, revije, neposredno pošto in embalažo) in opisali njihove prednosti in slabosti. Z anketnim vprašalnikom smo ugotavljali, na katere barve smo najbolj pozorni in katerim lastnostim se posamezne barve bolj približajo. Osredotočili smo se na sedem barv

  7. O ensino de enfermagem em saúde mental e psiquiátrica: visão do professor e do aluno na perspectiva da fenomenologia social La enseñanza de enfermería en salud mental y psiquiátrica: visión del profesor y del alumno en la perspectiva de la fenomenología social Teaching of nursing in mental and psychiatric health: the point-of-view of teachers and students in a social phenomenology perspective

    Directory of Open Access Journals (Sweden)

    Marcos Antonio Campoy

    2005-04-01

    Full Text Available O objetivo deste estudo foi compreender o processo ensino-aprendizagem na perspectiva do professor e do aluno que vivenciaram a disciplina de enfermagem em saúde mental e psiquiátrica. Analisaram-se os dados coletados por meio de entrevistas com alunos e professores que vivenciaram o fenômeno, segundo o referencial da fenomenologia social. Emergiram categorias concretas de significado do vivido pelos professores : valorizando a comunicação e a relação entre as pessoas; aprendendo a considerar o outro como pessoa; valorizando o cuidado integral, desmitificando medos e pré-conceitos e atribuindo significado ao autoconhecimento. Pelos alunos: percebendo a relevância do conhecimento sobre comunicação e da relação entre as pessoas; aprendendo a ver o outro como pessoa; aplicando conhecimento adquirido para o cuidado integral; sentindo-se motivado a mudar de atitude; reconhecendo o significado do autoconhecimento. A tipificação foi descrita ao final. O processo ensino-aprendizagem nessa disciplina, desperta interesse pela especialidade, desenvolvimento pessoal e valorização da sua utilização na enfermagem geral.El objetivo de este estudio fue comprender el proceso enseñanza-aprendizaje en la perspectiva del profesor y del alumno que vivenciaron la disciplina de enfermería en salud mental y psiquiátrica. Se analizaron los datos recopilados por medio de entrevistas, con alumnos y profesores que vivenciaron el fenómeno, según el referencial de la fenomenología social. Emergieron categorías concretas de significado de lo vivido por los profesores: valorizando la comunicación y la relación entre las personas; aprendiendo a considerar al otro como persona; valorizando el cuidado integral, desmitificando miedos y prejuicios y atribuyendo significado al autoconocimiento. Por los alumnos: percibiendo la relevancia del conocimiento sobre comunicación y de la relación entre las personas; aprendiendo a ver al otro como persona

  8. Novas estratégias de posicionamento na fidelização do consumidor infantil de alimentos processados New positioning strategies for fidelization of child consumers of processed food

    Directory of Open Access Journals (Sweden)

    Ângela Rozane Leal de Souza

    2012-03-01

    Full Text Available As crianças estão assumindo um papel cada vez mais importante nas decisões de consumo familiar em função de sua crescente influência e autonomia na escolha dos produtos adquiridos, o que as torna um segmento de mercado cada vez mais visado nas estratégias de marketing das empresas de produtos manufaturados. Essa dinâmica é particularmente importante no mercado de alimentos infantis, em que se estabelecem necessidades, às vezes contraditórias, de integrar a busca por alimentos saudáveis (pelos pais saborosos e valorizados (muitas vezes em função de atributos extrínsecos pelos filhos. Esta pesquisa evidenciou que a adoção de padrões de alimentação inadequados tem gerado a emergência de novos problemas de saúde na população infantil brasileira. Esse quadro é agravado por um contexto institucional marcado pelo conflito de parte do setor processador de alimentos e órgãos públicos de regulação - em particular no que diz respeito à competência de regular a publicidade de alimentos para esse segmento de consumidores. Ao largo desse debate, as empresas líderes no mercado de alimentos infantis, em grande parte multinacionais, procuram alinhar a oferta de alimentos cada vez mais saudáveis aos consumidores infanto-juvenis, atendendo uma tendência inexorável nesse setor. É inconcebível, portanto, que o estabelecimento de uma regulamentação rígida e específica sobre as informações veiculadas na propaganda e publicidade de alimentos, voltados ao público infantil, por órgãos públicos isentos, beneficiando não apenas os consumidores, mas também a empresa preocupada em garantir a boa qualidade de seus produtos, não represente uma bandeira comum do setor processador de alimentos no Brasil.Children have taken an increasingly important role in consumption-related family decision-making due to a growing influence and autonomy in choosing the products to be bought, and this has turned them into a market segment that

  9. Validação do Questionário do Hospital Saint George na Doença Respiratória (SGRQ em pacientes portadores de doença pulmonar obstrutiva crônica no Brasil

    Directory of Open Access Journals (Sweden)

    SOUSA THAIS COSTA DE

    2000-01-01

    Full Text Available Introdução: O termo qualidade de vida tem adquirido cada vez mais importância no contexto científico. O presente estudo descreve a adaptação para as língua e cultura brasileiras de um questionário doença-específico desenvolvido por Paul Jones et al. em 1991(1: o Questionário do Hospital Saint George na Doença Respiratória (SGRQ, para a avaliação de qualidade de vida em pacientes portadores de doença pulmonar obstrutiva crônica (DPOC. Esse questionário contém três componentes (sintomas, atividade e impactos divididos em 76 itens. É auto-administrado e pode ser lido para pacientes analfabetos. Objetivo: Verificar se o SGRQ é um instrumento válido para medir qualidade de vida em pacientes portadores de DPOC no Brasil. Métodos: Para a validação deste questionário no Brasil, realizou-se, inicialmente, uma versão da língua inglesa para o português; em seguida, foi realizada a tradução retrógrada (back translation, do português para o inglês, e uma versão final foi aplicada em 30 pacientes com diagnóstico de DPOC, estáveis clinicamente e baseado em critérios de espirometria e oximetria. Os pacientes responderam ao questionário por duas vezes, num intervalo de 15 dias. O tempo de resposta foi cronometrado e as dúvidas apontadas pelos pacientes, anotadas. Foi utilizado o teste estatístico de Wilcoxon para cálculo de probabilidade de r e calculado o coeficiente de correlação intraclasse para testar a fidedignidade e a confiabilidade do questionário. Resultados: Dos 30 pacientes que participaram do estudo, 10 eram do sexo feminino e 20 do masculino. A média de idade foi de 65,9 anos. A maioria dos pacientes encontrava-se no estádio 2 (56,7% da DPOC, segundo a classificação da American Thoracic Society. O coeficiente de correlação intraclasse para a pontuação total do questionário foi a = 0,79 e o resultado do teste de Wilcoxon p = 0,2110 (não significante estatisticamente. O tempo médio de resposta

  10. Mudanças na composição e adequação nutricional da dieta familiar nas áreas metropolitanas do Brasil (1988-1996

    Directory of Open Access Journals (Sweden)

    Monteiro Carlos Augusto

    2000-01-01

    Full Text Available OBJETIVO: Atualizar a tendência secular (1962-1988 da composição e da adequação nutricional da dieta familiar praticada nas áreas metropolitanas do Brasil, com base em nova pesquisa sobre orçamentos familiares realizada em meados da década de 90. MÉTODOS: Utilizaram-se como fontes de dados as pesquisas sobre orçamentos familiares (POF da Fundação IBGE, realizadas entre março de 1987 e fevereiro de 1988 (13.611 domicílios e entre outubro de 1995 e setembro de 1996 (16.014 domicílios, tendo ambas como universo de estudo as áreas metropolitanas do Brasil. Nas duas pesquisas chegou-se à disponibilidade domiciliar diária per capita de alimentos, dividindo-se o total de alimentos adquiridos no mês pelo número de pessoas residentes no domicílio e pelo número de dias do mês. O padrão alimentar foi caracterizado com base na participação relativa de grupos selecionados de alimentos e de nutrientes na disponibilidade calórica total. A comparação entre as duas pesquisas levou em conta o conjunto das áreas metropolitanas do País e estratos dessas áreas correspondentes às regiões menos desenvolvidas (Norte e Nordeste e mais desenvolvidas (Centro-Oeste, Sudeste e Sul. RESULTADOS: Observou-se intensificação do consumo relativo de carnes, de leites e de seus derivados (exceto manteiga em todas as áreas metropolitanas, enquanto o consumo de ovos passou a declinar, sobretudo no Centro-Sul do País. Leguminosas, raízes e tubérculos prosseguiram sua trajetória descendente, mas cereais e derivados tenderam a se estabilizar no Centro-Sul ou mesmo a se elevar ligeiramente no Norte-Nordeste. A participação relativa de açúcar refinado e refrigerantes cresceu em todas as áreas, sendo que a participação de óleos e gorduras vegetais manteve-se constante no Norte-Nordeste e declinou intensamente no Centro-Sul. CONCLUSÕES: A tendência ascendente da participação relativa de lipídios na dieta do Norte e do Nordeste, o aumento

  11. Na/K Pump and Beyond: Na/K-ATPase as a Modulator of Apoptosis and Autophagy.

    Science.gov (United States)

    Felippe Gonçalves-de-Albuquerque, Cassiano; Ribeiro Silva, Adriana; Ignácio da Silva, Camila; Caire Castro-Faria-Neto, Hugo; Burth, Patrícia

    2017-04-21

    Lung cancer is a leading cause of global cancer deaths. Na/K-ATPase has been studied as a target for cancer treatment. Cardiotonic steroids (CS) trigger intracellular signalling upon binding to Na/K-ATPase. Normal lung and tumour cells frequently express different pump isoforms. Thus, Na/K-ATPase is a powerful target for lung cancer treatment. Drugs targeting Na/K-ATPase may induce apoptosis and autophagy in transformed cells. We argue that Na/K-ATPase has a role as a potential target in chemotherapy in lung cancer treatment. We discuss the effects of Na/K-ATPase ligands and molecular pathways inducing deleterious effects on lung cancer cells, especially those leading to apoptosis and autophagy.

  12. Scintillation efficiency measurement of Na recoils in NaI(Tl) below the DAMA/LIBRA energy threshold

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Jingke; Shields, Emily; Calaprice, Frank; Westerdale, Shawn; Froborg, Francis; Suerfu, Burkhant; Alexander, Thomas; Aprahamian, Ani; Back, Henning O.; Casarella, Clark; Fang, Xiao; Gupta, Yogesh K.; Ianni, Aldo; Lamere, Edward; Lippincott, W. Hugh; Liu, Qian; Lyons, Stephanie; Siegl, Kevin; Smith, Mallory; Tan, Wanpeng; Kolk, Bryant Vande

    2015-07-01

    The dark matter interpretation of the DAMA modulation signal depends on the NaI(Tl) scintillation efficiency of nuclear recoils. Previous measurements for Na recoils have large discrepancies, especially in the DAMA/LIBRA modulation energy region. We report a quenching effect measurement of Na recoils in NaI(Tl) from 3 to 52 keVnr, covering the whole DAMA/LIBRA energy region for dark matter-Na scattering interpretations. By using a low-energy, pulsed neutron beam, a double time-of-flight technique, and pulse-shape discrimination methods, we obtained the most accurate measurement of this kind for NaI(Tl) to date. The results differ significantly from the DAMA reported values at low energies but fall between the other previous measurements. We present the implications of the new quenching results for the dark matter interpretation of the DAMA modulation signal.

  13. Na/K Pump and Beyond: Na/K-ATPase as a Modulator of Apoptosis and Autophagy

    Directory of Open Access Journals (Sweden)

    Cassiano Felippe Gonçalves-de-Albuquerque

    2017-04-01

    Full Text Available Lung cancer is a leading cause of global cancer deaths. Na/K-ATPase has been studied as a target for cancer treatment. Cardiotonic steroids (CS trigger intracellular signalling upon binding to Na/K-ATPase. Normal lung and tumour cells frequently express different pump isoforms. Thus, Na/K-ATPase is a powerful target for lung cancer treatment. Drugs targeting Na/K-ATPase may induce apoptosis and autophagy in transformed cells. We argue that Na/K-ATPase has a role as a potential target in chemotherapy in lung cancer treatment. We discuss the effects of Na/K-ATPase ligands and molecular pathways inducing deleterious effects on lung cancer cells, especially those leading to apoptosis and autophagy.

  14. A interdisciplinaridade na violência sexual

    OpenAIRE

    Azambuja,Maria Regina Fay de

    2013-01-01

    O artigo aborda a inquirição da vítima de violência sexual como afronta aos direitos humanos da criança, na medida em que busca a obtenção da prova em detrimento da proteção da vítima. Aponta a ação interdisciplinar como indispensável ao trabalho envolvendo violência sexual praticada contra a criança, dando ênfase à perícia realizada por profissionais de diversas áreas (Serviço Social, Psicologia, Pedagogia, Pediatra) como instrumento capaz de produzir a prova e de garantir a dignidade e o re...

  15. Symbiodinium isolation by NaOH treatment.

    Science.gov (United States)

    Zamoum, Thamilla; Furla, Paola

    2012-11-15

    The presence of photosynthetic zooxanthellae (dinoflagellates) in the tissue of many cnidarians is the main reason for their ecological success (i.e. coral reefs). It could also be the main cause of their demise, as the worldwide bleaching of reef-building coral is nothing less than the breakdown of this symbiotic association. The stability of this relationship is the principal marker for the biomonitoring of cnidarian health. We have therefore developed a new, simple method to isolate zooxanthellae in a few steps using NaOH solution. The protocol was validated in three symbiotic cnidarian species: a sea anemone, a gorgonian and a coral. Our method allows the isolation of intact and viable zooxanthellae with better yields than classic methods, especially for species with a calcareous skeleton. Moreover, the isolated zooxanthellae were free of host nucleic contaminants, facilitating subsequent specific molecular analyses.

  16. Pion and kaon freezeout in NA44

    International Nuclear Information System (INIS)

    1994-01-01

    The NA44 spectrometer is optimized for the study of single and two-particle particle spectra near mid-rapidity for transverse momenta below ∼ 1 GeV/c. A large fraction of all pairs in the spectrometer's acceptance are at low relative momenta, resulting in small statistical uncertainties on the extracted size parameters. In addition, the spectrometer's clean particle identification allows the authors to measure correlation functions for pions, kaons, and protons. This contribution will concentrate on the source size parameters determined from pion and kaon correlation functions. These size parameters will be compared to calculations from the RQMD event generator and also interpreted in the context of a hydrodynamic model. Finally, the measured single particle spectra will be examined from the viewpoint of hydrodynamics

  17. Redes sociais na internet: Sociabilidades emergentes

    OpenAIRE

    Amaral, Inês

    2016-01-01

    Na actual era da cultura digital é imperativo identificar e compreender os tipos de sociabilidade que emergem das novas práticas e relações que ocorrem no ciberespaço, para que seja possível teorizar sobre realidades sociais que são desenhadas em torno da apropriação do conteúdo e materializadas em plataformas que se assumem como o termómetro de uma sociedade sem determinismo geográfico. A sociabilização em contexto digital reporta-se ao princípio de que um mundo de informação (conteúdos, ...

  18. O operar de um coletivo na WEB

    Directory of Open Access Journals (Sweden)

    Karen Eidelwein

    Full Text Available Analisamos o operar de um grupo de discussão na WEB buscando identificar seu agenciamento enquanto coletivo autoprodutivo. Estabelecemos sete indicadores de operação e cinco categorias temáticas. A visualização de cada um dos indicadores de operação em cada uma das categorias temáticas possibilitou compreender o operar do grupo como decorrente das próprias relações que foram sendo estabelecidas, em um processo autoprodutivo, de causalidade recursiva. Foi possível argumentar que o grupo apresentou indícios de um modo de instituir-se capaz de apontar para outras formas de relação em torno da construção de objetos coletivos teóricos voltados para a ação fora do espaço digital.

  19. Bullying: ato esburacado na angústia

    Directory of Open Access Journals (Sweden)

    Maria de Lourdes Soares Ornellas

    2012-04-01

    Full Text Available A noção de afeto está no campo do (desprazer, resultante de uma experiência afetiva de satisfação ou insatisfação, e que se manifesta nas necessidades do sujeito. Pode-se dizer que o afeto envolve a ambivalência de sentimentos, do mais agradável ao mais insuportável, e desempenha um papel estruturante para que o sujeito reencontre sua estrutura psíquica, exercendo uma ação mediadora e decisiva sobre a constituição do sujeito do desejo, orientando o seu projeto de vida, sua profissão, sua opção sexual, etc. Essa ambivalência de afetos deve ser exercitada na educação familiar e escolar, na fala e na escuta que o afeto (desprazeroso tem relevância e parece ser silenciado. O desprazer pode ser escandido pelos sintomas medo, depressão, irritabilidade, ansiedade, humilhação. Assim posto o bullying é também conhecido como a síndrome da humilhação. O objetivo da humilhação é a tentativa de destruição do sujeito; a perda da identificação revela um fantasma, na medida em que própria vítima se sente culpada por sofrer ou por estar sofrendo um ato esburacado porque uma das peças não é encontrada e, em lugar do encaixe, o que se mostra é um buraco, o que provoca a angústia entre quem perde e aquele que ganha. ABSTRACT: The notion of affect is thus in the field of (dis pleasure, resulting from an affective experience of satisfaction or dissatisfaction, and that manifests itself on the needs of the subject. You could say that the affection involves the ambivalence of feelings, the more enjoyable the more unbearable, and plays a structural role for the subject to rediscover his psychic structure, exerting a mediator and decisive action on the constitution of the subject of desire, directing the its design life, your profession, your sexual orientation, etc.. This ambivalence of feelings should be exercised in family education and school, talking and listening that affect (dis pleasure is relevant and appears to be

  20. The NA49 large acceptance hadron detector

    International Nuclear Information System (INIS)

    Afanasiev, S.; Alber, T.; Appelshaeuser, H.; Baechler, J.; Barna, D.; Barnby, L.S.; Bartke, J.; Barton, R.A.; Betev, L.; Bialkowska, H.; Bieser, F.; Billmeier, A.; Blyth, C.O.; Bock, R.; Bormann, C.; Bracinik, J.; Brady, F.P.; Brockmann, R.; Brun, R.; Buncic, P.; Caines, H.L.; Cebra, D.; Cooper, G.E.; Cramer, J.G.; Csato, P.; Cyprian, M.; Dunn, J.; Eckardt, V.; Eckhardt, F.; Empl, T.; Eschke, J.; Ferguson, M.I.; Fessler, H.; Fischer, H.G.; Flierl, D.; Fodor, Z.; Frankenfeld, U.; Foka, P.; Freund, P.; Friese, V.; Ftacnik, J.; Fuchs, M.; Gabler, F.; Gal, J.; Ganz, R.; Gazdzicki, M.; Gladysz, E.; Grebieszkow, J.; Guenther, J.; Harris, J.W.; Hegyi, S.; Henkel, T.; Hill, L.A.; Hlinka, V.; Huang, I.; Huemmler, H.; Igo, G.; Irmscher, D.; Ivanov, M.; Janik, R.; Jacobs, P.; Jones, P.G.; Kadija, K.; Kolesnikov, V.I.; Kowalski, M.; Lasiuk, B.; Levai, P.; Liebicher, K.; Lynen, U.; Malakhov, A.I.; Margetis, S.; Markert, C.; Marks, C.; Mayes, B.; Melkumov, G.L.; Mock, A.; Molnar, J.; Nelson, J.M.; Oldenburg, M.; Odyniec, G.; Palla, G.; Panagiotou, A.D.; Pestov, Y.; Petridis, A.; Pikna, M.; Pimpl, W.; Pinsky, L.; Piper, A.; Porter, R.J.; Poskanzer, A.M.; Poziombka, S.; Prindle, D.J.; Puehlhofer, F.; Rauch, W.; Reid, J.G.; Renfordt, R.; Retyk, W.; Ritter, H.G.; Roehrich, D.; Roland, C.; Roland, G.; Rudolph, H.; Rybicki, A.; Sammer, T.; Sandoval, A.; Sann, H.; Schaefer, E.; Schmidt, R.; Schmischke, D.; Schmitz, N.; Schoenfelder, S.; Semenov, A.Yu.; Seyboth, J.; Seyboth, P.; Seyerlein, J.; Sikler, F.; Sitar, B.; Skrzypczak, E.; Squier, G.T.A.; Stelzer, H.; Stock, R.; Strmen, P.; Stroebele, H.; Struck, C.; Susa, T.; Szarka, I.; Szentpetery, I.; Szymanski, P.; Sziklai, J.; Toy, M.; Trainor, T.A.; Trentalange, S.; Ullrich, T.; Vassiliou, M.; Veres, G.; Vesztergombi, G.; Vranic, D.; Wang, F.Q.; Weerasundara, D.D.; Wenig, S.; Whitten, C.; Wieman, H.; Wienold, T.; Wood, L.; Yates, T.A.; Zimanyi, J.; Zhu, X.-Z.; Zybert, R.

    1999-01-01

    The NA49 detector is a wide acceptance spectrometer for the study of hadron production in p+p, p+A, and A+A collisions at the CERN SPS. The main components are 4 large-volume TPCs for tracking and particle identification via dE/dx. TOF scintillator arrays complement particle identification. Calorimeters for transverse energy determination and triggering, a detector for centrality selection in p+A collisions, and beam definition detectors complete the set-up. A description of all detector components is given with emphasis on new technical realizations. Performance and operational experience are discussed in particular with respect to the high track density environment of central Pb+Pb collisions

  1. The NA49 large acceptance hadron detector

    CERN Document Server

    Afanasiev, S V; Appelshäuser, H; Bächler, J; Barna, D; Barnby, L S; Bartke, Jerzy; Barton, R A; Betev, L; Bialkowska, H; Bieser, F; Billmeier, A; Blyth, C O; Böck, R K; Bormann, C; Bracinik, J; Brady, F P; Brockmann, R; Brun, R; Buncic, P; Caines, H L; Cebra, D; Cooper, G E; Cramer, J G; Csató, P; Cyprian, M; Dunn, J; Eckardt, V; Eckhardt, F; Empl, T; Eschke, J; Ferguson, M I; Fessler, H; Fischer, H G; Flierl, D; Fodor, Z; Frankenfeld, Ulrich; Foka, P Y; Freund, P; Friese, V; Ftácnik, J; Fuchs, M; Gabler, F; Gál, J; Ganz, R E; Gazdzicki, M; Gladysz-Dziadus, E; Grebieszkow, J; Günther, J; Harris, J W; Hegyi, S; Henkel, T; Hill, L A; Hlinka, V; Huang, I; Hümmler, H; Igo, G; Irmscher, D; Ivanov, M; Janik, R; Jacobs, P; Jones, P G; Kadija, K; Kolesnikov, V I; Kowalski, M; Lasiuk, B; Lévai, Peter; Liebicher, K; Lynen, U; Malakhov, A I; Margetis, S; Markert, C; Marks, C; Mayes, B W; Melkumov, G L; Mock, A; Molnár, J; Nelson, J M; Oldenburg, M; Odyniec, Grazyna Janina; Pálla, G; Panagiotou, A D; Pestov, Yu N; Petridis, A; Pikna, M; Pimpl, W; Pinsky, L; Piper, A; Porter, R J; Poskanzer, A M; Poziombka, S; Prindle, D J; Pühlhofer, F; Rauch, W; Reid, J G; Renfordt, R E; Retyk, W; Ritter, H G; Röhrich, D; Roland, C; Roland, G; Rudolph, H; Rybicki, A; Sammer, T; Sandoval, A; Sann, H; Schäfer, E; Schmidt, R; Schmischke, D; Schmitz, N; Schönfelder, S; Semenov, A Yu; Seyboth, J; Seyboth, P; Seyerlein, J; Siklér, F; Sitár, B; Skrzypczak, E; Squier, G T A; Stelzer, H; Stock, Reinhard; Strmen, P; Ströbele, H; Struck, C; Susa, T; Szarka, I; Szentpétery, I; Szymanski, P; Sziklai, J; Toy, M; Trainor, T A; Trentalange, S; Ullrich, T S; Vassiliou, Maria; Veres, G I; Vesztergombi, G; Vranic, D; Wang, F; Weerasundara, D D; Wenig, S; Whitten, C; Wieman, H H; Wienold, T; Wood, L; Yates, T A; Zimányi, J; Zhu, X Z; Zybert, R

    1999-01-01

    The NA49 detector is a wide acceptance spectrometer for the study of hadron production in p+p, p+A, and A+A collisions at the CERN SPS. The main components are 4 large volume TPCs for tracking and particle identification via $dE/dx$. TOF scintillator arrays complement particle identification. Calorimeters for transverse energy determination and triggering, a detector for centrality selection in p+A collisions, and beam definition detectors complete the set-up. A description of all detector components is given with emphasis on new technical realizations. Performance and operational experience are discussed in particular with respect to the high track density environment of central Pb+Pb collisions.

  2. Hotel na Vysočině

    OpenAIRE

    Machatka, Petr

    2013-01-01

    Diplomová práce s názvem Hotel na Vysočině řeší projektovou dokumentaci ve stupni pro provedení stavby. Hotel má tři nadzemní podlaží. Objekt je nepodsklepený. Zastřešení je provedeno plochou a šikmou střechou. Zdící systém POROTHERM s kontaktním zateplením expandovaným polystyrenem EPS -F. The master thesis named Hotel at Vysočina solves project documentation in the degree for building construction. The hotel has three floors. The object is without a cellar. As roofing is used a flat and ...

  3. O retorno do religioso na contemporaneidade

    Directory of Open Access Journals (Sweden)

    Tiago Ribeiro Nunes

    2008-12-01

    Full Text Available O presente trabalho pretende analisar os novos modos de relação, entre a civilização e o sagrado, que emergem no contexto da contemporaneidade. Partindo principalmente das formulações freudianas e lacanianas sobre o tema, nosso objetivo primordial ao longo deste artigo é estabelecer parâmetros para compreender a ocorrência do "retorno ao sagrado no exato momento em que a humanidade enfrenta crises cada vez mais profundas e permanentes. Tal empreendimento nos permitirá verificar até que ponto o fortalecimento dos movimentos religiosos pode ser considerado como uma das conseqüências da queda dos referenciais que se realiza na contemporaneidade.

  4. Estágio na Compta

    OpenAIRE

    Mendes, Dário Miguel dos Santos

    2017-01-01

    O presente documento descreve o trabalho realizado no segundo ano letivo do Mestrado em Produção de Conteúdos Digitais. Relatando um estágio decorrido na empresa tecnológica Compta S.A. Neste relatório é feita uma apresentação da empresa, bem como os seus objetivos como tal. De seguida, efetua-se um enquadramento do estágio no âmbito contextual dos conteúdos digitais, descrevendo as tecnologias utilizadas, necessárias à criação de aplicações para dispositivos móveis. São ainda apresentados...

  5. Solubility of NaNd(CO3)2.6H2O(c) in concentrated Na2CO3 and NaHCO3 solutions

    International Nuclear Information System (INIS)

    Rao, L.; Rai, D.; Felmy, A.R.; Fulton, R.W.; Novak, C.F.

    1996-01-01

    NaNd(CO 3 ) 2 x 6 H 2 O(c) was identified to be the final equilibrium solid phase in suspensions containing concentrated sodium carbonate (0.1 to 2.0 M) and sodium bicarbonate (0.1 to 1.0 M), with either NaNd(CO 3 ) 2 x 6 H 2 O(c) or Nd 2 (CO 3 ) 3 x xH 2 O(s) as initial solids. A thermodynamic model, based on Pitzer's specific into-interaction approach, was developed to interpret the solubility of NaNd(CO 3 ) 2 x 6 H 2 O(c) as functions of sodium carbonate and sodium bicarbonate concentrations. In this model, the solubility data of NaNd(CO 3 ) 2 x 6 H 2 O(c) were explained by assuming the formation of NdCO 3 + , Nd(CO 3 ) 2 - and Nd(CO 3 ) 3 3- species and invoking the specific ion interactions between Na + and Nd(CO 3 ) 3 3- . Ion interaction parameters for Na + -Nd(CO 3 ) 3 3- were developed to fit the solubility data. Based on the model calculations, Nd(CO 3 ) 3 3- was the predominant aqueous neodymium species in 0.1 to 2 M sodium carbonate and 0.1 to 1 M sodium bicarbonate solutions. The logarithm of the NaNd(CO 3 ) 2 x 6 H 2 O solubility product (NaNd(CO 3 ) 2 x 6 H 2 O(c)=Na + +Nd 3+ +2 CO 3 2- +6 H 2 O) was calculated to be -21.39. This model also provided satisfactory interpretation of the solubility data of the analogous Am(III) system in less concentrated carbonate and bicarbonate solutions. (orig.)

  6. Videogames e o aprender na complexidade

    Directory of Open Access Journals (Sweden)

    Paula Cristina Turcatto

    2016-06-01

    Full Text Available Ao conceber-se esta pesquisa, levou-se em consideração que cada ser humano aprende do seu modo pessoal e único, portanto, a proposta é pensar os videogames na sua relação com o Paradigma da Complexidade. Esta pesquisa teve como objetivo proporcionar um ambiente de encontro com diversos jogos de videogame, buscando instaurar a experimentação do novo, a abertura para o conhecer, ao habitar espaços inventivos, que valorizam a plasticidade e flexibilidade. Trata-se de uma pesquisa qualitativa, pois se propôs a trabalhar com os aspectos subjetivos como uma dimensão inseparável do conhecer. Foram 8 sujeitos de pesquisa – adolescentes – com os quais foram realizados 15 encontros, nos quais os mesmos estiveram em contato com diversos jogos de videogame. Foram utilizados diários de bordo para o registro das vivências, ancorados na metodologia cartográfica para tratamento dos registros. Os videogames propiciaram espaços para a emergência de diferentes formas de vivenciar a narrativa. Apesar de os jogos serem pré-moldados, os percursos produzidos, assim como as produções simbólicas frente ao contexto do jogo foram individuais. Jogar videogame relacionou-se ao posicionamento criador, de escrever as circunstâncias sob as quais as ações do jogo refletiram nas experiências vivenciadas pelo jogador.

  7. Insulin regulation of (Na+, K+)-ATPase

    International Nuclear Information System (INIS)

    Lytton, J.

    1985-01-01

    This thesis describes an investigation into the mechanism of insulin stimulation of (Na + ,K + )=ATPase in rat adipocytes. Two molecular forms of the catalytic subunit of the enzyme were identified and denoted α and α(+), due to their similarity to those isozymes previously described from rat brain. Insulin specifically stimulated the α(+) form of the enzyme. The two forms of the enzyme had quite different affinities for intracellular sodium ion; insulin affected only the lower affinity of α(+), shifting it toward a higher value. However, the sodium affinity of (Na + ,K + )-ATPase activity in isolated membranes was equally high for both forms of the enzyme. This suggests that the difference in sodium affinity between the two forms observed in the cell is not inherent within the structure of the sodium pump, but must depend upon a selective interaction with another molecule which has been lost upon membrane isolation. Immunoprecipitation of both the catalytic subunits either from extracts of whole cells which had been labelled with [ 32 P] orthophosphate, or from membranes which had been labelled with γ-[ 32 P]ATP demonstrated that less than 1 in 100 molecules had a covalently bound phosphate insulin had no influence on this value. The amino terminal sequences of the first 4 amino acids of the catalytic subunits of both α (isolated from rat kidney) and α(+) (from rat brainstem axolemma) were determined. The result shows two highly homologous but clearly different molecules. It can thus be concluded that the insulin sensitive version of the enzyme is not derived from the common α form by a post-translational modification

  8. Porta-enxertos utilizados na citricultura

    Directory of Open Access Journals (Sweden)

    Schäfer Gilmar

    2001-01-01

    Full Text Available A muda cítrica é o insumo mais importante na formação de um pomar. As características mais importantes da muda cítrica são a origem do enxerto e do porta-enxerto, a qualidade do sistema radicular e a sua sanidade. Os porta-enxertos são capazes de influenciar várias características horticulturais e sanitárias nas árvores e nos frutos cítricos, como: sólidos solúveis totais, tamanho da copa e do fruto, resistência a moléstias e ao frio, distribuição da raízes, etc. O principal porta-enxerto utilizado no Brasil (cerca de 80% é o limoeiro ?Cravo? (Citrus limonia Osbeck cv. Cravo. No Rio Grande do Sul, mais especificamente, destaca-se o Poncirus trifoliata (L. Raf em mais de 90% dos pomares. Isso torna a citricultura vulnerável ao surgimento de moléstias que afetem estes porta-enxertos, como ocorreu na década de 40 em todo o Brasil com a 'Tristeza' dos citros em plantas enxertadas sobre laranjeira azeda, e, mais recentemente, com o 'declínio'. Assim, o conhecimento das características dos diversos porta-enxertos e de algumas particularidades do uso destes é de grande importância para a diversificação e escolha do porta-enxerto a ser utilizado pelo citricultor.

  9. PERSPECTIVA MULTIDIMENSIONAL DO TRABALHO NA CONTEMPORANEIDADE

    Directory of Open Access Journals (Sweden)

    Lilian Carminatti

    2015-12-01

    Full Text Available O objetivo deste estudo é analisar a evolução do tema trabalho e novas formas de flexibilização das relações laborais que proporcionam identidade, significado e bem-estar. O trabalho, como uma atividade prazerosa, passa por uma mudança de postura das pessoas frente à atividade ocupacional, a partir do autoconhecimento, planejamento de carreira e de uma jornada de trabalho que vislumbre a melhora na qualidade de vida. A promoção do bem-estar presume a articulação entre as relações de trabalho atravessadas pelo sistema capitalista e a importância de equilibrar necessidades individuais e a competitividade organizacional. Como elementos balizadores surgem: a relação com os significados do trabalho, o planejamento de carreira e pós-carreira e a conexão entre valores pessoais e organizacionais. Adotou-se para a pesquisa uma estratégia metodológica qualitativa que se propõe a investigar a partir da exploração e descrição as dimensões do tema trabalho na sociedade contemporânea. Dessa forma, a promoção do bem-estar e o planejamento de carreira devem ser tratados como planejamento de vida durante todo o período funcional, a partir de uma visão multidimensional do colaborador inserida em um amplo contexto cultural e social que ultrapassa o ambiente organizacional.

  10. Mercury's Na Exosphere from MESSENGER Data

    Science.gov (United States)

    Killen, Rosemary M.; Burger, M. H.; Cassidy, T. A.; Sarantos, M.; Vervack, R. J.; McClintock, W. El; Merkel, A. W.; Sprague, A. L.; Solomon, S. C.

    2012-01-01

    MESSENGER entered orbit about Mercury on March 18, 2011. Since then, the Ultraviolet and Visible Spectrometer (UWS) channel of MESSENGER's Mercury Atmospheric and Surface Composition Spectrometer (MASCS) has been observing Mercury's exosphere nearly continuously. Daily measurements of Na brightness were fitted with non-uniform exospheric models. With Monte Carlo sampling we traced the trajectories of a representative number of test particles, generally one million per run per source process, until photoionization, escape from the gravitational well, or permanent sticking at the surface removed the atom from the simulation. Atoms were assumed to partially thermally accommodate on each encounter with the surface with accommodation coefficient 0.25. Runs for different assumed source processes are run separately, scaled and co-added. Once these model results were saved onto a 3D grid, we ran lines of sight from the MESSENGER spacecraft :0 infinity using the SPICE kernels and we computed brightness integrals. Note that only particles that contribute to the measurement can be constrained with our method. Atoms and molecules produced on the nightside must escape the shadow in order to scatter light if the excitation process is resonant-light scattering, as assumed here. The aggregate distribution of Na atoms fits a 1200 K gas, with a PSD distribution, along with a hotter component. Our models constrain the hot component, assumed to be impact vaporization, to be emitted with a 2500 K Maxwellian. Most orbits show a dawnside enhancement in the hot component broadly spread over the leading hemisphere. However, on some dates there is no dawn/dusk asymmetry. The portion of the hot/cold source appears to be highly variable.

  11. LUZ, MELATONINA E ESTRESSE OXIDATIVO NA PISCICULTURA

    Directory of Open Access Journals (Sweden)

    Claudio Alberto Gellis de Mattos Dias

    2013-12-01

    Full Text Available Em peixes, como nos mamíferos, partes do sistema nervoso estão envolvidas em mecanismos para regulação dos sistemas corporais em sintonia com o meio. O fotoperíodo é traduzido em informações fisiológicas a partir da secreção de melatonina.Parece não haver barreiras morfofisiológicas para esta indolamina, isto é, a melatonina perfunde-se rapidamente em cada célula do organismo e em alguns casos interage com receptores e membrana situados na superfície celular, e parece estar ligada à ingestão de alimentos, crescimento e atividade locomotora de peixes. São moléculas importantes metabolizando espécies reativas de oxigênio a produtos inativos e, portanto, reduzindo o dano oxidativo.Este trabalho tem por objetivo fazer um breve levantamento em artigos recentes sobre luminosidade, melatonina e o estresse oxidativo em peixes, e correlaciona-los com piscicultura. Concluímos que a luminosidade parece estar ligada a produção de melatonina, e esta molécula antioxidante, que favorece a redução do estresse oxidativo, parecem melhorar o desempenho na produção de peixes em criadouros. Palavras-chave: Melatonina, estresse oxidativo, piscicultura. DOI: http://dx.doi.org/10.18561/2179-5746/biotaamazonia.v3n3p169-176

  12. Diffusion of calcium in pure and doped NaCl; Diffusion du calcium dans NaCl pur et dope

    Energy Technology Data Exchange (ETDEWEB)

    Slifkin, L; Brebec, G [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1969-07-01

    We have determined, by diffusion experiments of Ca in pure and doped NaCl, the activation energy for the calcium jumps and the binding energy between calcium ion and vacancy. (authors) [French] Nous avons determine, par des mesures de diffusion du Ca dans NaCl pur et NaCl dope avec CaCl{sub 2}, l'energie d'activation relative aux sauts du calcium et l'energie de liaison lacune-calcium. (auteurs)

  13. Mechanism of μ-conotoxin PIIIA binding to the voltage-gated Na+ channel NaV1.4.

    Directory of Open Access Journals (Sweden)

    Rong Chen

    Full Text Available Several subtypes of voltage-gated Na+ (NaV channels are important targets for pain management. μ-Conotoxins isolated from venoms of cone snails are potent and specific blockers of different NaV channel isoforms. The inhibitory effect of μ-conotoxins on NaV channels has been examined extensively, but the mechanism of toxin specificity has not been understood in detail. Here the known structure of μ-conotoxin PIIIA and a model of the skeletal muscle channel NaV1.4 are used to elucidate elements that contribute to the structural basis of μ-conotoxin binding and specificity. The model of NaV1.4 is constructed based on the crystal structure of the bacterial NaV channel, NaVAb. Six different binding modes, in which the side chain of each of the basic residues carried by the toxin protrudes into the selectivity filter of NaV1.4, are examined in atomic detail using molecular dynamics simulations with explicit solvent. The dissociation constants (Kd computed for two selected binding modes in which Lys9 or Arg14 from the toxin protrudes into the filter of the channel are within 2 fold; both values in close proximity to those determined from dose response data for the block of NaV currents. To explore the mechanism of PIIIA specificity, a double mutant of NaV1.4 mimicking NaV channels resistant to μ-conotoxins and tetrodotoxin is constructed and the binding of PIIIA to this mutant channel examined. The double mutation causes the affinity of PIIIA to reduce by two orders of magnitude.

  14. Anisotropy and polarization in charge changing collisions of C4+ with Na(3s) and laser aligned Na(3p)

    NARCIS (Netherlands)

    Hoekstra, R; Morgenstern, R; Olson, RE

    1996-01-01

    Absolute cross sections for C3+(6-->5) emission at 465.7 nm after collisions of C4+ ions with ground state Na(3s) and laser excited aligned Na(Sp) atoms are measured over the collision energy range of 3-7 keV amu(-1). For Na(3s) polarizations are observed by measuring the linear polarization of the

  15. Qual o Papel da Escola e da Mídia na Obtenção dos Conhecimentos Astronômicos?

    Science.gov (United States)

    da Cunha, W. S.; Voelzke, M. R.; Amaral, L. H.

    2007-08-01

    É amplamente reconhecido que as pessoas em geral têm grande fascínio e interesse pela Astronomia. Por outro lado, o conteúdo dessa área incluído no ensino formal está longe de ser abrangente e suficiente para suprir a demanda. Esse interesse permite aperfeiçoar a divulgação e o ensino não formal de Astronomia através da mídia aliando a adequação do conteúdo à expectativa das pessoas. A reforma do Currículo Básico da Escola Pública da maioria dos Estados brasileiros tem introduzido Astronomia desde a pré-escola até o Ensino Médio. Num estudo realizado com 1180 alunos do Ensino Médio de seis escolas estaduais, revelou-se através da aplicação de um formulário contendo questões que abordavam conhecimentos básicos em Astronomia, como foram adquiridos tais conhecimentos e à infra-estrutura da escola. Para 66,1% dos entrevistados o professor já fez alguma apresentação a respeito de Astronomia. O presente estudo revelou também que 54,4% dos alunos entrevistados adquiriram seus conhecimentos astronômicos na escola, 18,4% através da televisão e 27,1% afirmaram que seus conhecimentos foram obtidos através de outros tipos de mídia (internet, livros didáticos, filmes e revistas). Embora o estudo revele claramente que há certo equilíbrio no meio em que os alunos obtiveram seus conhecimentos astronômicos, a mídia busca não somente sua difusão, mas a disponibilização desse conhecimento de maneira correta, que às vezes, não é atingido, apresentando conceitos sem fundamentação e incorretos. Por outro lado, no dia-a-dia escolar, é comum encontrar professores que vêm para as aulas com concepções prévias, que podem diferir substancialmente das idéias a serem ensinadas, dificultando o aprendizado de futuros conceitos científicos. Uma avaliação criteriosa, avaliando as dificuldades dos professores em determinar o sentido correto dos conceitos e observando a metodologia que utilizam no ensino, poderá proporcionar uma melhor

  16. Crystal structure of polyphosphates NaCd(PO3)3 and NaMn(PO3)3

    International Nuclear Information System (INIS)

    Murashova, E.V.; Chudinova, N.N.

    1997-01-01

    Crystal structure of NaCd(PO 3 ) 3 (1) and NaMn(PO 3 ) 3 (2) isostructural polyphosphates was determined for twin samples. Rhombic lattice parameters of (1): a = 14.678, b = 14.669, c = 14.705 A, sp. gr. P2 1 2 1 2 1 , Z = 16. The structure of compounds is of frame type. Polyphosphate chain with repetition period of 24 PO 4 tetrahedrons contacts with NaO 6 and M 2 O 6 octahedrons by means of common oxygen vertices. Similarities and differences in structure of mentioned polyphosphates and earlier analyzed NaMg(PO 3 ) 3 polyphosphate are noted [ru

  17. UTJECAJ POZITIVNE DISKRIMINACIJE NA UKLJUČIVANJE ŽENA NA TRŽIŠTE RADA U REPUBLICI HRVATSKOJ

    OpenAIRE

    Dovranić, Dora; Katavić, Ivica

    2016-01-01

    U početku 21. stoljeća često se koristi pojam pozitivne (afirmativne) diskriminacije. Pozitivna diskriminacija mjera je koju poduzima vlada, neka organizacija ili korporacija s ciljem da se smanje nejednakosti u društvu nastale upravo diskriminacijom, na način da se pružaju određene povlastice onima koji su pretrpjeli neku vrstu diskriminacije. Nastala je u Sjedinjenim Američkim Državama na inicijativu predsjednika Kennedyja, Johnsona i Nixona. Diskriminacija, nažalost, ima mnogo oblika, a ne...

  18. 43. Calmodulin regulating calcium sensitivity of Na channels

    Directory of Open Access Journals (Sweden)

    R. Vegiraju

    2016-07-01

    Full Text Available By extrapolating information from existing research and observing previous assumptions regarding the structure of the Na Channel, this experiment was conducted under the hypothesis that the Na Channel is in part regulated by the calmodulin protein, as a result proving calcium sensitivity of the Na Channel. Furthermore, we assume that there is a one to one stoichiometry between the Na Channel and the Calmodulin. There has been extensive research into the functionality and structure of sodium ion channels (Na channels, as several diseases are associated with the lack of regulation of sodium ions, that is caused by the disfunction of these Na channels. However, one highly controversial matter in the field is the importance of the protein calmodulin (CaM and calcium in Na channel function. Calmodulin is a protein that is well known for its role as a calcium binding messenger protein, and that association is believed to play an indirect role in regulating the Na channel through the Na channel’s supposed calcium sensitivity. While there are proponents for both sides, there has been relatively little research that provides strong evidence for either case. In this experiment, the effect of calmodulin on NaV 1.5 is tested by preparing a set of cardiac cells (of the human specie with the NaV 1.5 C-Termini and CaM protein, which were then to be placed in solutions with varying concentrations of calcium. We took special care to test multiple concentrations of calcium, as previous studies have tested very low concentrations, with Manu Ben-Johny’s team from the John Hopkins laboratory in particular testing up to a meager 50 micromolar, despite producing a well-respected paper (By comparison, the average Na channel can naturally sustain a concentration of almost 1-2 millimolar and on some occasions, reaching even higher concentrations. After using light scattering and observing the signals given off by the calcium interacting with these Nav1.5/Ca

  19. Impact of childhood stress on psychopathology Impacto de estresse na infância na psicopatologia

    Directory of Open Access Journals (Sweden)

    Elisa Brietzke

    2012-12-01

    Full Text Available OBJECTIVE: Advances in our knowledge of mental disorder (MD genetics have contributed to a better understanding of their pathophysiology. Nonetheless, several questions and doubts persist. Recent studies have focused on environmental influences in the development of MDs, and the advent of neuroscientific methodologies has provided new perspectives. Early life events, such as childhood stress, may affect neurodevelopment through mechanisms such as gene-environment interactions and epigenetic regulation, thus leading to diseases in adulthood. The aim of this paper is to review the evidence regarding the role of the environment, particularly childhood stress, in the pathophysiology of MD. METHODOLOGY: We reviewed articles that evaluated environmental influences, with a particular focus on childhood trauma, brain morphology, cognitive functions, and the development of psychopathology and MD. RESULTS AND CONCLUSION: MRI studies have shown that exposure to trauma at an early age can result in several neurostructural changes, such as the reduction of the hippocampus and corpus callosum. Cognitive performance and functioning are also altered in this population. Finally, childhood stress is related to an increased risk of developing MD such as depression, bipolar disorder, schizophrenia and substance abuse. We conclude that there is robust evidence of the role of the environment, specifically adverse childhood experiences, in various aspects of MD.OBJETIVO: Avanços no conhecimento da genética dos transtornos mentais (TM contribuíram para um melhor entendimento de suas bases fisiopatológicas. No entanto, dúvidas e questões ainda persistem. Estudos recentes têm se concentrado nas influências do ambiente no desenvolvimento de TM, e o advento de metodologias neurocientíficas oferece novas perspectivas. Eventos precoces de vida, como estresse na infância, podem ser capazes de alterar o neurodesenvolvimento através de mecanismos como intera

  20. Measurement of direct CP-violation with the experiments NA31 and NA48 at CERN

    International Nuclear Information System (INIS)

    Renk, B.

    1992-01-01

    The NA31 experiment has measured the CP violation parameter var-epsilon '/var-epsilon. The result of data collected in 1988 is Re(var-epsilon '/var-epsilon)=(1.7±1.0)x10 -3 . A preliminary result of data collected in 1989 is Re(var-epsilon '/var-epsilon)=(2.1±0.9)x10 -3 . Combining these two results with the original result from the 1986 data set we obtain Re(var-epsilon '/var-epsilon)=(2.3±0.7)x10 -3 , which is a more than three standard deviation evidence for direct CP violation. A new experiment NA48 is under construction which aims for a significant reduction of the statistical and the systematical errors in order to reach a combined error not exceeding 2x10 -4

  1. O Platonismo de Russell na metafísica e na matemática

    Directory of Open Access Journals (Sweden)

    Guido Imaguire

    2005-06-01

    Full Text Available Neste artigo, analiso o surgimento e a superação do Platonismo em B. Russell, tanto na sua filosofia da matemática como na sua metafísica. Começo por explicitar os argumentos que levaram Russell a aderir ao chamado "Platonismo Proposicional" - posição que será tecnicamente relevante na definição de números. Na seção seguinte, discutirei até que ponto a teoria das descrições definidas determina, necessariamente, uma adesão ao nominalismo, e as dificuldades que surgem para o logicismo conseqüentes do abandono do platonismo. Finalmente, mostrarei como a posição madura de Russell caracteriza-se mais como um reducionismo do que propriamente como um nominalismo, e como este é fundado no princípio do mínimo vocabulário.In this paper, I analyze the emergence and the overcoming of Platonism both in Russell's philosophy of mathematics and his metaphysics. I begin by examining the arguments which led Russell to endorse a position that I term "Propositional Platonism" - this position proves to be relevant for Russell's definition of numbers. In the following section, I address the question of the extent to which Russell's theory of descriptions implies the acceptance of nominalism. Moreover, I examine the difficulties which arise for logicism, if it no longer goes hand in hand with platonism. Finally, I argue argue that Russell's mature position is to be characterized as a form of reductionism rather than as a variant of nominalism

  2. LASERTERAPIA NA INFLAMAÇÃO PULMONAR EXPERIMENTAL EM RATTUS NORVEGICUS OCASIONADO PELA PAPAÍNA

    Directory of Open Access Journals (Sweden)

    Diego Rodrigues Pessoa

    2017-01-01

    Full Text Available Resumo: A Doença Pulmonar Obstrutiva Crônica (DPOC é caracterizada pela limitação do fluxo aéreo decorrente da dilatação dos espaços aéreos distais aos bronquíolos terminais. Analisar os efeitos da laserterapia quanto ao processo cicatricial na lesão pulmonar experimental em Rattus Novergicus. Utilizaram-se trinta animais agrupados em três grupos de dez animais: grupo controle (GC (não recebeu nada, grupo DPOC (GD (foi pulverizado 3 doses de papaína 3mg/kg e grupo DPOC + Laser (GDL (após 7 dias da indução da lesão com papaína foi tratado com laser de 660 nm durante 15 dias.Para analise dos resultados foi realizado o lavado broncoalveolar. Quanto ao Lavado: GC (número de células normais, GD (aumento de células inflamatórias e GDL (diminuição de células inflamatórias. A laserterapia diminui o numero de células inflamatórias, entretanto, não possui efeito reconstrutor do parênquima pulmonar apenas estabiliza a lesão comprovando sua ação anti-inflamatória.

  3. Isolation and preliminary function analysis of a Na + /H + antiporter ...

    African Journals Online (AJOL)

    A full-length cDNA Na+/H+ antiporter gene (MzNHX1) was isolated from Malus zumi according to the homologous Na+/H+ antiporter gene region in plants. Sequence analysis indicated that the cDNA was 2062 bp in length, including an open reading frame (ORF) of 1629 bp, which encoded a predicted polypeptide of 542 ...

  4. Transepithelial Na+ transport and the intracellular fluids: a computer study.

    Science.gov (United States)

    Civan, M M; Bookman, R J

    1982-01-01

    Computer simulations of tight epithelia under three experimental conditions have been carried out, using the rheogenic nonlinear model of Lew, Ferreira and Moura (Proc. Roy. Soc. London. B 206:53-83, 1979) based largely on the formulation of Koefoed-Johnsen and Ussing (Acta Physiol. Scand. 42: 298-308. 1958). First, analysis of the transition between the short-circuited and open-circuited states has indicated that (i) apical Cl- permeability is a critical parameter requiring experimental definition in order to analyze cell volume regulation, and (ii) contrary to certain experimental reports, intracellular Na+ concentration (ccNa) is expected to be a strong function of transepithelial clamping voltage. Second, analysis of the effects of lowering serosal K+ concentration (csK) indicates that the basic model cannot simulate several well-documented observations; these defects can be overcome, at least qualitatively, by modifying the model to take account of the negative feedback interaction likely to exist between the apical Na+ permeability and ccNa. Third, analysis of the strongly supports the concept that osmotically induced permeability changes in the apical intercellular junctions play a physiological role in conserving the body's stores of NaCl. The analyses also demonstrate that the importance of Na+ entry across the basolateral membrane is strongly dependent upon transepithelial potential, cmNa and csK; under certain conditions, net Na+ entry could be appreciably greater across the basolateral than across the apical membrane.

  5. A mudança organizacional na teoria administrativa

    OpenAIRE

    Silveira Júnior, Aldery; Oliveira, Waldyr Viegas de

    1996-01-01

    Discorre sobre a mudança organizacional na teoria administrativa, abordando a natureza da mudança, como ela se insere no contexto das organizações e como ela se desenvolveu na história da administração.

  6. High resolution laser spectroscopy of the D lines of on-line produced 21Na, 22Na, 24Na, 25Na using a new high sensitivity method of detection of optical resonances

    International Nuclear Information System (INIS)

    Huber, G.; Thibault, G.; Klapisch, R.; Duong, H.T.; Vialle, J.L.; Pinard, I.; Juncar, P.; Jacquinot, P.

    1975-01-01

    A polyisotopic sodium beam of 21 - 25 Na, produced by spallation of Al, was illuminated by a tunable dye laser. The atomic beam, analyzed by a sixpole magnet is then ionized and detected after a mass spectrometer. The results are the isotope shifts, nuclear magnetic moment and quadrupole moment of 25 Na [fr

  7. Numerična in eksperimentalna analiza delovanja Teslinega ventilatorja

    OpenAIRE

    Lukačič, Rajko

    2017-01-01

    Nikola Tesla je patentiral ventilator, ki deluje na principu trenja. V diplomskem delu je opisano delovanje Teslinega ventilatorja in teoretično ozadje njegovega delovanja z namenom zmanjševanja hrupa. V sami raziskavi smo s programom Ansys izdelali numerični model, ki temelji na turbulentnem modelu k-

  8. Risbjerg: SF vandt valgkampen, NA og R tabte

    DEFF Research Database (Denmark)

    Thomsen, Søren Risbjerg

    2007-01-01

    ANALYSE: Endnu engang flyttede en valgkamp for alvor stemmer. SF gik undervejs 27 pct. frem, mens NA gik 34 pct. tilbage og R 26 pct. Udgivelsesdato: 25. november......ANALYSE: Endnu engang flyttede en valgkamp for alvor stemmer. SF gik undervejs 27 pct. frem, mens NA gik 34 pct. tilbage og R 26 pct. Udgivelsesdato: 25. november...

  9. MCHANGO WA MWALIMU J.K. NYERERE KATIKA TAFSIRI NA ...

    African Journals Online (AJOL)

    Kwa kuzingatia tafsiri mbili za J.K. Nyerere, Julius Kaizer (1963) na Mabepari wa Venus (1969), makala inaeleza: (i) kwa nini Mwalimu Nyerere alitafsiri maandishi ya Shakespeare, (ii) ufanisi wa tafsiri zake, na (iii) mchango wa tafsiri hizo. Makala inaonyesha kuwa tafsiri hizo zinazingatia mbinu za kisemantiki zaidi kuliko ...

  10. Kuingiliana kwa Lugha ya Kiswahili na Kiingereza: Uswahilishaji wa ...

    African Journals Online (AJOL)

    Kuingiliana kwa lugha ni taaluma katika uwanja wa isimu inayohusu lugha zinazoingiliana na kuathiriana. Kuingiliana kwa lugha sio jambo jipya katika dunia. Watu ambao ndio watumiaji wa lugha wamesababisha lugha kuiingiliana waliposafiri au kuhama sehemu moja hadi nyingine kutokana na sababu za kiuchumi, ...

  11. Ufundishaji wa Kusoma na Kuandika Kiswahili: Uzoefu wa Idara ya ...

    African Journals Online (AJOL)

    Makala haya yanahusu shughuli za kufundisha Kiswahili kama lugha ya kigeni katika Chuo Kikuu cha Sebha nchini Libya. Kwanza inaeleza historia ya Kiswahili – yaani kilianza lini kufundishwa kwa madhumuni gani na nani walikuwa wanzilishi. Halikadhalika makala ya naeleza utaratibu uliowekwa na idara ili kuweza ...

  12. Juhudi za Vyombo vya Habari katika Kukuza na Kueneza Kiswahili ...

    African Journals Online (AJOL)

    Vyombo vya habari ni asasi muhimu sana katika kukuza na kueneza lugha yoyote ile, hasa katika enzi hii ya utandawazi. Vyombo hivyo ni kama vile idhaa za redio, televisheni na magazeti. Katika nchi ya Kenya kuna vyombo vya habari vinavyotoa huduma anuwai kwa ajili ya kutosheleza mahitaji ya wateja wao. Katika ...

  13. Substrate Specificity of Na+,Cl-(HCO3-)-ATPase.

    Science.gov (United States)

    Yurkiv, V A; Melikhov, V I; Shubin, V S

    2016-09-01

    We studied substrate specificity of Na + ,Cl - (HCO 3 - )-ATPase. In most cases, replacement of ATP for other phosphate-containing substances resulted in not only pronounced suppression of phosphohydrolase reactions, but also dramatic changes of their responsiveness to the stimulating effect of monovalent ions. The data showed that Na + ,Cl - (HCO 3 - )-ATPase is a highly specific enzyme for ATP.

  14. Optimization and kinetics decomposition of monazite using NaOH

    International Nuclear Information System (INIS)

    MV Purwani; Suyanti; Deddy Husnurrofiq

    2015-01-01

    Decomposition of monazite with NaOH has been done. Decomposition performed at high temperature on furnace. The parameters studied were the comparison NaOH / monazite, temperature and time decomposition. From the research decomposition for 100 grams of monazite with NaOH, it can be concluded that the greater the ratio of NaOH / monazite, the greater the conversion. In the temperature influences decomposition 400 - 700°C, the greater the reaction rate constant with increasing temperature greater decomposition. Comparison NaOH / monazite optimum was 1.5 and the optimum time of 3 hours. Relations ratio NaOH / monazite with conversion (x) following the polynomial equation y = 0.1579x 2 – 0.2855x + 0.8301 (y = conversion and x = ratio of NaOH/monazite). Decomposition reaction of monazite with NaOH was second orde reaction, the relationship between temperature (T) with a reaction rate constant (k), k = 6.106.e - 1006.8 /T or ln k = - 1006.8/T + 6.106, frequency factor A = 448.541, activation energy E = 8.371 kJ/mol. (author)

  15. Sepsis does not alter red blood cell glucose metabolism or Na+ concentration: A 2H-, 23Na-NMR study

    International Nuclear Information System (INIS)

    Hotchkiss, R.S.; Song, S.K.; Ling, C.S.; Ackerman, J.J.; Karl, I.E.

    1990-01-01

    The effects of sepsis on intracellular Na+ concentration ([Na+]i) and glucose metabolism were examined in rat red blood cells (RBCs) by using 23Na- and 2H-nuclear magnetic resonance (NMR) spectroscopy. Sepsis was induced in 15 halothane-anesthetized female Sprague-Dawley rats by using the cecal ligation and perforation technique; 14 control rats underwent cecal manipulation without ligation. The animals were fasted for 36 h, but allowed free access to water. At 36 h postsurgery, RBCs were examined by 23Na-NMR by using dysprosium tripolyphosphate as a chemical shift reagent. Human RBCs from 17 critically ill nonseptic patients and from 7 patients who were diagnosed as septic were also examined for [Na+]i. Five rat RBC specimens had [Na+]i determined by both 23Na-NMR and inductively coupled plasma-atomic emission spectroscopy (ICP-AES). For glucose metabolism studies, RBCs from septic and control rats were suspended in modified Krebs-Henseleit buffer containing [6,6-2H2]glucose and examined by 2H-NMR. No significant differences in [Na+]i or glucose utilization were found in RBCs from control or septic rats. There were no differences in [Na+]i in the two groups of patients. The [Na+]i determined by NMR spectroscopy agreed closely with measurements using ICP-AES and establish that 100% of the [Na+]i of the RBC is visible by NMR. Glucose measurements determined by 2H-NMR correlated closely (correlation coefficient = 0.93) with enzymatic analysis. These studies showed no evidence that sepsis disturbed RBC membrane function or metabolism

  16. Experiments on cold trap regeneration by NaH decomposition

    International Nuclear Information System (INIS)

    McPheeters, C.C.; Skladzien, S.B.; Raue, D.J.

    1979-10-01

    Cold trap regeneration may be very important in future LMFBRs because of the expected high hydrogen source from the steam generators. This hydrogen precipitates as NaH in the cold trap and may fill the trap within one year of operation. Several methods of cold trap regeneration were considered, but the simplest and least expensive appears to be decomposition of NaH under vacuum at elevated temperatures. Experiments were done to assess the feasibility of this method for cold trap regeneration. Small-scale simulated cold traps (SCT) were located with NaH and NaH plus Na 2 O, and were heated both under vacuum and under a sweep gas at 100 kPa. The evolved hydrogen was converted to water by a CuO bed and collected in a weighting tube

  17. Na,K-pump modulates intercellular communication in vascular wall

    DEFF Research Database (Denmark)

    Matchkov, Vladimir; Nilsson, Holger; Aalkjær, Christian

      Ouabain, a specific inhibitor of the Na,K-pump, has previously been shown to interfere with intercellular communication. Here we test the hypothesis that the communication between vascular smooth muscle cells (SMCs) is regulated through an interaction between the Na,K-pump and the Na...... were used as a model for electrical coupling of SMCs by measuring membrane capacitance (Cm). SMCs were uncoupled (evaluated by inhibition of vasomotion and desynchronization of calcium transients in vascular wall, or by reduction to half of Cm measured in paired A7r5 cells) when the Na,K-pump...... was inhibited either by a low concentration of ouabain or by ATP depletion. Uncoupling with ouabain was associated with a localized increase of intracellular calcium in discrete sites near the plasma membrane. Reduction of Na,K-pump activity by removal of extracellular potassium also uncoupled cells, but only...

  18. Recent results from the NA62 experiment at CERN

    CERN Document Server

    Aliberti, Riccardo

    2016-01-01

    NA62 is a fixed target experiment located at the CERN SPS which aims to perform flavour physics studies in the charged kaon sector with an unprecedented precision. Due to the abundance of kaon decays with a po in the final state, NA62 is also a perfect environment to measure the neutral pion characteristics. NA62 collected a large sample of charged kaon decays with a highly efficient trigger for decays into electrons in 2007. We report about the measurement of the po electromagnetic transition form factor slope parameter in the time-like region. Between 2008 and 2014 the NA62 apparatus underwent an intense upgrade phase to improve the physics sensitivity of the experiment to precisely measure the Br (K+ !p+n ¯ n). NA62 took data in pilot runs in 2014 and 2015 reaching the final designed beam intensity. The quality of data acquired in view of the final measurement is presented.

  19. The New Readout System of the NA62 LKr Calorimeter

    CERN Document Server

    Ceccucci, A; Farthouat, P; Lamanna, G; Rouet, J; Ryjov, V; Venditti, S

    2015-01-01

    The NA62 experiment [1] at CERN SPS (Super Proton Synchrotron) accelerator aims at studying Kaon decays with high precision. The high resolution Liquid Krypton (LKr) calorimeter, built for the NA48 [2] experiment, is a crucial part of the photon-veto system; to cope with the demanding NA62 re- quirements,itsback-endelectron icshadtobecompletelyrenewed. The new readout system is based on the Calorimeter REAdout Module (CREAM) [3], a 6U VME board whose design and pro- duction was sub-contracted to CAEN [4], with CERN NA62 group continuously supervising the de velopment and production phase. The first version of the board was delivered by the manufacturer in March 2013 and, as of June 2014, the full board production is ongoing. In addition to describing the CREAM board, all aspects of the new LKr readout system, including its integration within the NA62 TDAQ scheme, will be treated.

  20. Crystal Structure of Na3MoCl6

    Directory of Open Access Journals (Sweden)

    Martin Beran

    2011-07-01

    Full Text Available The ternary chloride Na3MoCl6 is obtained as red crystals from a disproportionation reaction of molybdenum dichloride, {Mo6}Cl12, in an acidic NaCl/AlCl3 melt at 350 °C. The crystal structure (trigonal, P-31c, a = 687.1(1, c = 1225.3(2 pm, Z = 2, V = 501,0(1 106 pm3 is that of Na3CrCl6: within a hexagonal closest-packing of chloride ions two thirds of the octahedral voids are filled between the AB double layers with Na+/Mo3+, and between the BA layers with Na+.

  1. Dynamic polarizabilities and Van der Waals coefficients for alkali atoms Li, Na and alkali dimer molecules Li2, Na2 and NaLi

    Science.gov (United States)

    Mérawa, M.; Dargelos, A.

    1998-07-01

    The present paper gives an account of investigations of the polarizability of the alkali atoms Li, Na, diatomics homonuclear and heteronuclear Li2, Na2 and NaLi at SCF (Self Consistent Field) level of approximation and at correlated level, using a time Time-Dependent Gauge Invariant method (TDGI). Our static polarizability values agree with the best experimental and theoretical determinations. The Van der Waals C6 coefficients for the atom-atom, atom-dimer and dimer-dimer interactions have been evaluated. Les polarisabilités des atomes alcalins Li, Na, et des molécules diatomiques homonucléaires et hétéronucléaire Li2, Na2 et NaLi, ont été calculées au niveau SCF (Self Consistent Field) et au niveau corrélé à partir d'une méthode invariante de jauge dépendante du temps(TDGI). Nos valeurs des polarisabilités statiques sont en accord avec les meilleurs déterminations expérimentales et théoriques. Les coefficients C6 de Van de Waals pour les interactions atome-atome, atome-dimère et dimère-dimère ont également été évalués.

  2. Fanfictions: leitura e escrita na cibercultura

    Directory of Open Access Journals (Sweden)

    Monica do Amparo Silva

    2017-12-01

    Full Text Available A condição letrada é um fenômeno de natureza complexa e multifacetada. Organiza-se em torno de um conjunto de gestos e comportamentos diversificados, de competências e habilidades heterogêneas, de objetos histórica e socialmente diferenciados; é construída por meio de um conjunto de práticas e de uma rede de instituições, agentes e materiais; responsável por grandes divisões no interior da sociedade e um dos fatores que poderiam transformá-la. O ingresso na cultura escrita por sociedades ocidentais já foi considerado uma das principais evoluções da era moderna. Dominar a escrita era também a produzir. Contemporaneamente, uma sociedade civilizada chega a exigir de seus membros o domínio e utilização da leitura de variados suportes em variadas formas (pois cada suporte acaba por desenvolver um modo de leitura peculiar. Pode-se, pois, inferir que o ato de ler é um ato de esforço e concentração que também exige reflexão. Dessa forma, a leitura assume o papel de um processo de disciplina intelectual, exigindo uma posição crítica daquele que é o leitor. Os ciberjovens não só consomem a leitura e toda produção midiática. Eles interagem com essa produção e realizam uma recriação cultural com identidade e público próprios denominada fanfiction cuja escrita pode ser divulgada em diferentes plataformas do ciberespaço sob diversos gêneros textuais. Este artigo é resultado da reflexão baseada na observação de um app que permite a escrita/ leitura e a divulgação dessa produção.

  3. Kusheh, na minem Fatu, en mi na koko farmer Hello, I am Fatu and I am a cocoa farmer

    NARCIS (Netherlands)

    Witteveen, L.M.; Goris, Margriet; Lie, R.; Ingram, V.J.

    2016-01-01

    This document reports on the development of a prototype Digital Farmer Field School (DFFS) called Kusheh, na minem Fatu, en mi na koko farmer (“Hello, I am Fatu and I am a cocoa farmer”). The DFFS provides an ICT-based alternative to traditional agricultural extension. More specifically, it offers a

  4. Rescue of Na+ and H+ binding in Na+,K+-ATPase M8 aspartate mutants by secondary mutation

    DEFF Research Database (Denmark)

    Holm, Rikke; Einholm, Anja P.; Andersen, Jens Peter

    A mutation replacing the aspartate in transmembrane segment M8 in the a3-isoform of Na,K-ATPase with asparagine has been found in patients with rapid-onset dystonia parkinsonism or alternating hemiplegia of childhood. This aspartate may be a critical Na+ coordinating residue, but the crystal......-isoforms of Na,K-ATPase, and much smaller effects were seen for other mutations to the M8 aspartate, which were less disruptive of Na+ binding than mutations to other residues related to Na+ site III. The D928 (rat a1 numbering) mutations strongly diminished the cooperativity of Na+ binding. Moreover the p......H optimum of Na,K-ATPase activity was left-shifted, again with D928N being most disruptive. The reduced affinity for activating Na+ and for inhibitory protons, caused by D928N and D928A mutations, could be rescued by introduction of an additional mutation of a glutamate located far away from D928....

  5. Thermodiffusive behaviour of NaCl and KCl aqueous solutions a model for the Na-K pump

    International Nuclear Information System (INIS)

    Gaeta, F.S.; Mita, D.G.; Perna, G.; Scala, G.

    1975-01-01

    In NaCl and KCl aqueous nonisothermal solutions K + inverts its sense of migration within the physiological concentration range; Na + behaves similarly at much lower concentrations. These findings are discussed in relation to solute induced modifications of water structure and of their influence on thermal diffusion. A possible evolutionary model of a thermodiffusive mechanism for the sodium potassium pump is also suggested

  6. Evaluation of {sup 23}Na(n,2n){sup 22}Na reaction cross-sections

    Energy Technology Data Exchange (ETDEWEB)

    Manokhin, V N [Institute of Physics and Power Engineering, Obninsk (Russian Federation)

    1997-06-01

    Using available experimental data and (n,2n) excitation function systematics {sup 23}Na(n,2n){sup 22}Na reaction cross-sections were evaluated for energies ranging from the reaction threshold to 20 MeV. (author). 21 refs, 1 fig., 2 tabs.

  7. Endurance testing with Li/Na electrolyte

    Energy Technology Data Exchange (ETDEWEB)

    Ong, E.T.; Remick, R.J.; Sishtla, C.I. [Institute of Gas Technology, Des Plaines, IL (United States)

    1996-12-31

    The Institute of Gas Technology (IGT), under subcontract to M-C Power Corporation under DOE funding, has been operating bench-scale fuel cells to investigate the performance and endurance issues of the Li/Na electrolyte because it offers higher ionic conductivity, higher exchange current densities, lower vapor pressures, and lower cathode dissolution rates than the Li/K electrolyte. These cells have continued to show higher performance and lower decay rates than the Li/K cells since the publication of our two previous papers in 1994. In this paper, test results of two long-term 100-cm{sup 2} bench scale cells are discussed. One cell operated continuously at 160 mA/cm{sup 2} for 17,000 hours with reference gases (60H{sub 2}/20CO{sub 2}/20H{sub 2}O fuel at 75% utilization and 30CO{sub 2}/70 air oxidant humidified at room temperature at 50% utilization). The other cell operated at 160 mA/cm{sup 2} for 6900 hours at 3 atm with system gases (64H{sub 2}/16CO{sub 2}/20H{sub 2}O at 75% utilization and an M-C Power system-defined oxidant at 40% utilization). Both cells have shown the highest performance and longest endurance among IGT cells operated to date.

  8. Haveria uma antropologia infantil na modernidade?

    Directory of Open Access Journals (Sweden)

    José Carlos Souza Araujo

    2009-12-01

    Full Text Available Buscando situar uma conceituação de Modernidade, que se expressa paulatinamente a partir do século XIII, a criança e a infância são situadas como um fenômeno central na constituição da cultura ocidental a partir de então. O objeto deste trabalho é configurar alguns marcos filosóficos em torno da criança a partir do século XVI, representados pelas concepções de Martinho Lutero, Erasmo de Roterdão, Juan Luis Vives, Michel de Montaigne, John Locke, João Amós Comênio, Jean-Jacques Rousseau, Immanuel Kant, Johann Heinrich Pestalozzi, Friedrich W. A. Froebel, Johann Friedrich Herbart, William James, John Dewey e Antonio Gramsci. Evidentemente, tais pensadores revelam posições múltiplas, por vezes antagônicas, expressas através de antropologias assentadas no inatismo, no naturalismo, no deísmo, no empirismo, no cristianismo, no racionalismo, no idealismo, no materialismo histórico, entre outras. Entretanto, a criança é sempre situada em tais posicionamentos como um projeto inerente à cultura, constituindo-se a educação e a pedagogia como instrumentos para a sua formação.

  9. Lugares dos mortos na cristandade ocidental

    Directory of Open Access Journals (Sweden)

    Cláudia Rodrigues

    2013-01-01

    Full Text Available Resumo. Este artigo busca refletir sobre a forte associação entre morte e cristandade no Ocidente, buscando identificar os lugares dos mortos nos diferentes sistemas de cristandade. Propõe-se aqui a viabilidade de se pensar numa certa vinculação entre determinadas atitudes e representações diante da morte e do morrer e o sistema de cristandade vigente em determinados contextos históricos, entre fins da Antiguidade tardia e o século XX, mais especificamente em países nos quais a Igreja romana exerceu hegemonia sobre a sociedade. Procura argumentar que, enquanto predominou a modalidade “constantiniana”, os mortos faziam parte do cotidiano e a morte e foram instrumentos do projeto cristianizador. Quando este modelo de Cristandade recuou, diante da emergência da chamada “Cristandade pós-constantiniana” – na qual a Igreja não mais era braço do aparelho estatal –, os mortos tinham sido afastados da cidade dos vivos e a morte, ou melhor, o medo da morte não mais representava instrumento de pressão sobre a consciência do cidadão

  10. Energy stored in irradiated NaCl

    International Nuclear Information System (INIS)

    Lidiard, A.B.

    1979-01-01

    Recently reported measurements of the energy stored in heavily irradiated NaCl are reviewed in the light of recent understanding of radiation-damage processes in this material. It is shown that, in the ranges of temperatures and dose rates of these experiments, the F-centres produced by the irradiation are retained principally in the form of colloids: the stored energy is thus a direct measure of the number of F-centres retained in this form. Comparison of these results with the prediction of the recently proposed theory of colloid growth shows that the predictions of the dependence of colloid growth rates upon temperature and dose rate are qualitatively correct. The dependence of stored energy dose, however, appears to require the inclusion of a thermally activated back-reaction and possible modifications to the theory are briefly discussed. However, further experiments in this range of temperatures and dose rates are necessary for more quantitative tests of the theory. This reconsideration of the data does not alter the broad conclusion as to the relative insignificance of stored energy in a natural salt formation used as a radioactive waste repository, although more extensive measurements permitting a more exact test of theory would allow better predictions to be made for such applications. (author)

  11. Absorto na ação

    Directory of Open Access Journals (Sweden)

    Michael Fried

    2010-07-01

    Full Text Available O filme Zidane, um retrato do século XXI, de Douglas Gordon e Philippe Parreno (2006 pertence à tradição de absorção que desempenhou um papel crucial na evolução da arte moderna. O autor explora a tensão entre absorção e teatralidade - central tanto para a pintura francesa do século XVIII como para a fotografia dos séculos XX e XXI - e tira conseqüências estéticas e filosóficas do filme que retrata, ao longo de todos os noventa minutos de uma partida de futebol, o meio-campista francês Zinedine Zidane.Zidane, a 21st Century Portrait, a film by Douglas Gordon and Philippe Perreno, belongs to the absorptive tradition that has played a central role in the evolution of modern art. The author explores the tension between absorption and theatricality - crucial to 18th century French art as well as to 20th and 21th century photography - and draws aesthetic and philosophical consequences of this film that depicts, throughout all the 90 minutes of a soccer match, the French midfielder Zinedine Zidane.

  12. A Música Tradicional Madeirense na Transitoriedade

    Directory of Open Access Journals (Sweden)

    Rodolfo Cró

    2011-09-01

    Full Text Available O presente artigo procura expor, de uma forma sucinta, um conjunto de temáticas pertinentes ao contexto da música tradicional madeirense no atual panorama. Tendo como pano de fundo todas as transformações nos campos sociais, económicos e culturais, a contemporaneidade musical equaciona uma nova atitude, ou seja, uma necessidade reflexiva e crítica, face a um conjunto de elementos pluridimensionais. Contudo, a discussão em torno da globalização 1, ou seja “[…] o mundo como «aldeia global» […]” (Appadurai, 1996: 45 e da regionalização 2, ou seja, os “[…] particularismos ou culturas locais […]” (Featherstone, 2001: 84, em termos musicais, terá dese revestir numa proporção de dois conceitos, em que uma cultura conservadora dará lugar a uma cultura híbrida, no sentidoda modernidade. Tendo em conta que a evolução em princípio só se faz com programas culturais de renovação, experimentação e crítica (Canclini, 1992, é neste contexto que surgem as novas tecnologias; em concreto o software musical na sala de aula. Neste sentido, este artigo vem propor uma reflexão e um debate à luz de uma perspetiva cultural.

  13. Status for 2015, CERN NA63

    CERN Document Server

    Mikkelsen, RE; Wistisen, T

    2015-01-01

    We summarize the status for the CERN NA63 collaboration, where in 2015 we have had two runs at the CERN SPS, beamline H4: One with Ar ions at various energies around 75 GeV per nucleon, and one with electrons/positrons of 10-20 GeV. We previously refined and updated our theoretical analyses of bremsstrahlung and delta-electron emission from heavy, and medium-heavy, ultrarelativistic nuclei \\cite{Mikk15}. We thus concluded that - although not quite as interesting as for Pb projectiles - projectiles of Ar and/or Xe were suitable for the investigation, and for establishing the method to eventually measure the charge distribution of short-lived ($ct\\gtrsim3$m) fragments \\cite{Mikk14}. However, as the preliminary data analysis shows, the signal - which requires an intact projectile - is about three orders of magnitude lower than the background, stemming from photon emission (possibly originating from $\\pi^0$'s) in coincidence with projectiles that most likely are not intact after the collision. With the presently ...

  14. AVALIAÇÃO DAS CONDIÇÕES DE TRABALHO NO SETOR INDUSTRIAL: UMA ABORDAGEM CENTRADA NA ERGONOMIA FÍSICA E ORGANIZACIONAL

    OpenAIRE

    SANTOS, Isaac José Antonio Luquetti dos; MOREIRA, Maria de Lourdes

    2014-01-01

    As empresas estão sendo chamadas a atuar dentro de um novo contexto tecnológico empresarial a fim de proporcionar maior condição de conforto aos seus funcionários e procuram adaptar dentro do perfil econômico atual às mudanças, à competitividade do setor e às incertezas do mercado. Neste processo de mudança, tentam definir estratégias de diferentes níveis e necessita de um apoio efetivo para realizar suas intervenções com segurança compartilhando conhecimentos adquiridos através de uma ...

  15. Artesanato na terceira idade: um estudo na cidade de Sinop no ano de 2011

    Directory of Open Access Journals (Sweden)

    Rosane Marlene Weber

    2015-04-01

    Full Text Available Essa pesquisa tem como objetivo mostrar a importância do artesanato na Terceira Idade como atividade educacional e de autonomia para os idosos. Por existir uma preocupação com a qualidade de vida da Terceira Idade e sua autonomia, nesta fase que muitos acabam ficando dependentes dos membros da família, espera-se encontrar através da arte uma motivação e uma forma de demonstrar a autoria por meio do fazer, criar e recriar com o artesanato. Aprender e ensinar são um processo contínuo na vida do ser humano, independente da idade, para Paulo Freire precisamos ter consciência de que somos inacabados, e sendo conscientes de nossa inconclusão, devemos viver num permanente movimento de busca. Essa é uma das causas pelas quais será pesquisada a prática formativa/educacional por meio do artesanato na Terceira Idade. Os motivos que levaram a escolha desta pesquisa com o artesanato na Terceira Idade é o fato de ter vivido uma experiência de trabalho na ala geriátrica de um hospital. Já o artesanato é a arte que fascina, e acreditamos que sempre há tempo para recomeçar, para descobrir algo que possa trazer qualidade para nossa vida. Devido ao crescimento cada vez maior da expectativa de vida em nosso país, cria-se uma preocupação com a qualidade de vida das pessoas da Terceira Idade. Em relação aos aspectos educacionais e culturais, esta pesquisa deseja compreender como o artesanato pode trazer motivação para as pessoas da Terceira Idade como forma de autoria e autonomia, nesta fase da vida, na cidade de Sinop, e quais os motivos que os levam a realizar esse tipo de atividade. Para investigação teórica desta pesquisa do Artesanato na Terceira Idade: um estudo na cidade de Sinop em 2011 usaremos bibliografia de vários autores, mas em especial os que dedicam seus estudos a esta faixa etária, como a coleção de Vivaidade, que tem como organizadora principal Anita Liberalesso Neri. Os autores desta coleção nos trazem a reflex

  16. Synthesis of Ag or Pt Nanoparticles by Hydrolysis of Either Ag2Na or PtNa

    Directory of Open Access Journals (Sweden)

    Huabin Wang

    2008-01-01

    Full Text Available Ag and Pt nanoparticles have successfully been synthesized by hydrolysis of either Ag2Na or PtNa at room temperature. The oxidation of sodium in the Pt-Na pellets was much faster than that in the Ag-Na pellets since Pt is a catalyst for H2O formation reaction from hydrogen and oxygen at room temperature. The hydrolysis byproduct, NaOH, has a high solubility and easily is removed. This method offers a simple method of preparing transition metal nanoparticles. The Ag and Pt nanoparticles prepared by this method were crystalline in nature, and spherical in shape with a mean size of around 10 nm.

  17. Characterization and antibacterial activity of silver exchanged regenerated NaY zeolite from surfactant-modified NaY zeolite

    Energy Technology Data Exchange (ETDEWEB)

    Salim, Mashitah Mad; Malek, Nik Ahmad Nizam Nik, E-mail: niknizam@fbb.utm.my

    2016-02-01

    The antibacterial activity of regenerated NaY zeolite (thermal treatment from cetyltrimethyl ammonium bromide (CTAB)-modified NaY zeolite and pretreatment with Na ions) loaded with silver ions were examined using the broth dilution minimum inhibitory concentration (MIC) method against Escherichia coli (E. coli ATCC 11229) and Staphylococcus aureus (S. aureus ATCC 6538). X-ray diffraction (XRD), attenuated total reflectance–Fourier transform infrared (ATR–FTIR) spectroscopy, field emission scanning electron microscopy (FESEM), energy dispersive X-ray (EDX) and chemical elemental analyses were used to characterize the regenerated NaY and AgY zeolites. The XRD patterns indicated that the calcination and addition of silver ions on regenerated NaY zeolite did not affect the structure of the regenerated NaY zeolite as the characteristic peaks of the NaY zeolite were retained, and no new peaks were observed. The regenerated AgY zeolite showed good antibacterial activity against both bacteria strains in distilled water, and the antibacterial activity of the samples increased with increasing Ag loaded on the regenerated AgY zeolite; the regenerated AgY zeolite was more effective against E. coli than S. aureus. However, the antibacterial activity of the regenerated AgY was not effective in saline solution for both bacteria. The study showed that CTAB-modified NaY zeolite materials could be regenerated to NaY zeolite using thermal treatment (550 °C, 5 h) and this material has excellent performance as an antibacterial agent after silver ions loading. - Highlights: • Thermal treatment was used to regenerate surfactant modified zeolite. • The regenerated NaY zeolite formed was added with different silver loadings. • Regenerated AgY zeolite was tested for antibacterial activity on E. coli and S. aureus. • The antibacterial activity increased with increased of the amount of silver loadings. • The zeolite structure did not change with thermal and modification

  18. Characterization and antibacterial activity of silver exchanged regenerated NaY zeolite from surfactant-modified NaY zeolite

    International Nuclear Information System (INIS)

    Salim, Mashitah Mad; Malek, Nik Ahmad Nizam Nik

    2016-01-01

    The antibacterial activity of regenerated NaY zeolite (thermal treatment from cetyltrimethyl ammonium bromide (CTAB)-modified NaY zeolite and pretreatment with Na ions) loaded with silver ions were examined using the broth dilution minimum inhibitory concentration (MIC) method against Escherichia coli (E. coli ATCC 11229) and Staphylococcus aureus (S. aureus ATCC 6538). X-ray diffraction (XRD), attenuated total reflectance–Fourier transform infrared (ATR–FTIR) spectroscopy, field emission scanning electron microscopy (FESEM), energy dispersive X-ray (EDX) and chemical elemental analyses were used to characterize the regenerated NaY and AgY zeolites. The XRD patterns indicated that the calcination and addition of silver ions on regenerated NaY zeolite did not affect the structure of the regenerated NaY zeolite as the characteristic peaks of the NaY zeolite were retained, and no new peaks were observed. The regenerated AgY zeolite showed good antibacterial activity against both bacteria strains in distilled water, and the antibacterial activity of the samples increased with increasing Ag loaded on the regenerated AgY zeolite; the regenerated AgY zeolite was more effective against E. coli than S. aureus. However, the antibacterial activity of the regenerated AgY was not effective in saline solution for both bacteria. The study showed that CTAB-modified NaY zeolite materials could be regenerated to NaY zeolite using thermal treatment (550 °C, 5 h) and this material has excellent performance as an antibacterial agent after silver ions loading. - Highlights: • Thermal treatment was used to regenerate surfactant modified zeolite. • The regenerated NaY zeolite formed was added with different silver loadings. • Regenerated AgY zeolite was tested for antibacterial activity on E. coli and S. aureus. • The antibacterial activity increased with increased of the amount of silver loadings. • The zeolite structure did not change with thermal and modification

  19. Rigidification of the autolysis loop enhances Na(+) binding to thrombin.

    Science.gov (United States)

    Pozzi, Nicola; Chen, Raymond; Chen, Zhiwei; Bah, Alaji; Di Cera, Enrico

    2011-11-01

    Binding of Na(+) to thrombin ensures high activity toward physiological substrates and optimizes the procoagulant and prothrombotic roles of the enzyme in vivo. Under physiological conditions of pH and temperature, the binding affinity of Na(+) is weak due to large heat capacity and enthalpy changes associated with binding, and the K(d)=80 mM ensures only 64% saturation of the site at the concentration of Na(+) in the blood (140 mM). Residues controlling Na(+) binding and activation have been identified. Yet, attempts to improve the interaction of Na(+) with thrombin and possibly increase catalytic activity under physiological conditions have so far been unsuccessful. Here we report how replacement of the flexible autolysis loop of human thrombin with the homologous rigid domain of the murine enzyme results in a drastic (up to 10-fold) increase in Na(+) affinity and a significant improvement in the catalytic activity of the enzyme. Rigidification of the autolysis loop abolishes the heat capacity change associated with Na(+) binding observed in the wild-type and also increases the stability of thrombin. These findings have general relevance to protein engineering studies of clotting proteases and trypsin-like enzymes. Copyright © 2011 Elsevier B.V. All rights reserved.

  20. Rigidification of the autolysis loop enhances Na+ binding to thrombin

    Science.gov (United States)

    Pozzi, Nicola; Chen, Raymond; Chen, Zhiwei; Bah, Alaji; Di Cera, Enrico

    2011-01-01

    Binding of Na+ to thrombin ensures high activity toward physiological substrates and optimizes the procoagulant and prothrombotic roles of the enzyme in vivo. Under physiological conditions of pH and temperature, the binding affinity of Na+ is weak due to large heat capacity and enthalpy changes associated with binding, and the Kd=80 mM ensures only 64% saturation of the site at the concentration of Na+ in the blood (140 mM). Residues controlling Na+ binding and activation have been identified. Yet, attempts to improve the interaction of Na+ with thrombin and possibly increase catalytic activity under physiological conditions have so far been unsuccessful. Here we report how replacement of the flexible autolysis loop of human thrombin with the homologous rigid domain of the murine enzyme results in a drastic (up to 10-fold) increase in Na+ affinity and a significant improvement in the catalytic activity of the enzyme. Rigidification of the autolysis loop abolishes the heat capacity change associated with Na+ binding observed in the wild-type and also increases the stability of thrombin. These findings have general relevance to protein engineering studies of clotting proteases and trypsin-like enzymes. PMID:21536369

  1. Hormonal regulation of Na -K -ATPase in cultured epithelial cells

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, J.P.; Jones, D.; Wiesmann, W.P.

    1986-08-01

    Aldosterone and insulin stimulate Na transport through mechanisms involving protein synthesis. Na -K -ATPase has been implicated in the action of both hormones. The authors examined the effect of aldosterone and insulin on Na -K -ATPase in epithelial cells in culture derived from toad urinary bladder (TB6C) and toad kidney (A6). Aldosterone, but not insulin, increases short-circuit current (I/sub sc/) in TB6C cells. Aldosterone increases Na -K -(TSP)ATPase activity after 18 h of incubation, but no effect can be seen at 3 and 6 h. Amiloride, which inhibits aldosterone-induced increases in I/sub sc/, has no effect on either basal or aldosterone stimulated enzyme activity. Both aldosterone and insulin increase I/sub sc/ in A6 cells and when added together are synergistic. Aldosterone stimulates enzyme activity in A6 cells, but insulin alone has no effect. However, aldosterone and insulin together stimulate enzyme activity more than aldosterone alone. It appears that stimulation of Na -K -ATPase activity is involved in aldosterone action in both cell lines but does not appear to be due to increased Na entry, since enhanced enzyme activity is not inhibited by amiloride. In contrast, insulin alone has no direct effect on Na -K -ATPase, although the increased enzyme activity following both agents in combination may explain their synergism on I/sub sc/.

  2. NaIrO3-A pentavalent post-perovskite

    International Nuclear Information System (INIS)

    Bremholm, M.; Dutton, S.E.; Stephens, P.W.; Cava, R.J.

    2011-01-01

    Sodium iridium (V) oxide, NaIrO 3, was synthesized by a high pressure solid state method and recovered to ambient conditions. It is found to be isostructural with CaIrO 3 , the much-studied structural analog of the high-pressure post-perovskite phase of MgSiO 3 . Among the oxide post-perovskites, NaIrO 3 is the first example with a pentavalent cation. The structure consists of layers of corner- and edge-sharing IrO 6 octahedra separated by layers of NaO 8 bicapped trigonal prisms. NaIrO 3 shows no magnetic ordering and resistivity measurements show non-metallic behavior. The crystal structure, electrical and magnetic properties are discussed and compared to known post-perovskites and pentavalent perovskite metal oxides. -- Graphical abstract: Sodium iridium(V) oxide, NaIrO 3 , synthesized by a high pressure solid state method and recovered to ambient conditions is found to crystallize as the post-perovskite structure and is the first example of a pentavalent ABO 3 post-perovskite. Research highlights: → NaIrO 3 post-perovskite stabilized by pressure. → First example of a pentavalent oxide post-perovskite. → Non-metallic and non-magnetic behavior of NaIrO 3 .

  3. Sistematização da Assistência de Enfermagem na Rede Hospitalar de Uberaba: MG Sistematización de la asistencia de enfermería en la Red Hospitalaria de Uberaba: MG Systematization of Nursing Care in the Uberaba: MG hospital network

    Directory of Open Access Journals (Sweden)

    Karoline Faria de Oliveira

    2012-12-01

    Full Text Available O planeamento da assistência de enfermagem tem como finalidade a organização do cuidado a partir de um método sistemático, sendo o enfermeiro o responsável pelo seu desenvolvimento. Objetivos: verificar o conhecimento dos enfermeiros sobre a Sistematização da Assistência de Enfermagem (SAE na rede hospitalar de Uberaba e implantar a SAE num hospital privado do município. Método: estudo descritivo, exploratório e de intervenção. Primeira etapa: enfermeiros responderam um questionário semi-estruturado sobre as suas percepções em relação à SAE. Segunda etapa: implantação da SAE em hospital privado. Resultados: a maioria dos enfermeiros tinha incentivo institucional para implantação da SAE (60,29% e referia conhecê-la desde a graduação (91,18%, revelando desconexão entre o conhecimento da SAE adquirido na graduação e a prática profissional dos enfermeiros. Obstáculos para o uso da SAE: dificuldade na realização do exame físico (47,06%, do diagnóstico de enfermagem (36,76% e o acesso aos cursos de capacitação (85,71%. A implantação da SAE ocorreu no Centro de Terapia Intensiva (CTI de um hospital privado do município. Foram identificados os diagnósticos de enfermagem mais freqüentes na UTI, originando um documento impresso que passou a compor o prontuário dos pacientes. No verso deste documento constavam as prescrições de enfermagem, que após implementadas foram verificadas.La finalidad del planeamiento de la asistencia de enfermería es el organizar el cuidado a partir de un método sistemático. Objetivos: describir la percepción de los enfermeros sobre la Sistematización de la Asistencia de Enfermería (SAE en la red hospitalaria de Uberaba y la implantación de la SAE en un hospital privado. Método: estudio descriptivo, exploratorio y de intervención. Primer paso: los enfermeros respondieron a un cuestionario semiestruturado sobre sus percepciones con respecto a la SAE. Segundo paso: implantaci

  4. As valsas na Europa e na América do Sul

    OpenAIRE

    Almeida, Hélder António Moreira de

    2014-01-01

    Dissertação apresentado à Escola Superior de Artes Aplicadas do Instituto Politécnico de Castelo Branco para cumprimento dos requisitos necessários à obtenção do grau de Mestre em Performance. O objetivo deste trabalho é mostrar a história da valsa, a sua origem e influência de países da Europa Ocidental para a Europa do Sul como também a sua exportação Transatlântica para a América do sul. Pretendemos assim, mostrar o interesse destes compositores, na escrita desta forma mu...

  5. Search for dark photons in $\\pi^0$ decays at NA48 and NA62

    CERN Document Server

    Gonnella, Francesco

    2016-01-01

    The NA48/2 experiment at CERN collected, between 2003 and 2004, $1.69 \\times 10^{7}$ fully reconstructed $\\pi^{0} \\to \\gamma e^{+}e^{-}$ in the kinematic range $m_{ee}$ > 10 MeV/$c^{2}$, with a negligible background contamination. The sample is analysed to search for the presence of dark photons (${A}'$) via the decay chain $\\pi^{0} \\to \\gamma{A}', {A}' \\to e^{+}e^{-}$. No signal has been observed, and the exclusion limits on space of the dark photon mass $m_{{A}'}$ and the mixing parameter $e^{2}$ are reported.

  6. Electron scattering in graphene with adsorbed NaCl nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Drabińska, Aneta, E-mail: Aneta.Drabinska@fuw.edu.pl; Kaźmierczak, Piotr; Bożek, Rafał; Karpierz, Ewelina; Wysmołek, Andrzej; Kamińska, Maria [Faculty of Physics, University of Warsaw, Pasteura 5, 02-093 Warsaw (Poland); Wołoś, Agnieszka [Faculty of Physics, University of Warsaw, Pasteura 5, 02-093 Warsaw (Poland); Institute of Physics, Polish Academy of Sciences, Al. Lotników 32/46, 02-668 Warsaw (Poland); Pasternak, Iwona; Strupiński, Włodek [Institute of Electronic Materials Technology, Wólczyńska 133, 01-919 Warsaw (Poland); Krajewska, Aleksandra [Institute of Electronic Materials Technology, Wólczyńska 133, 01-919 Warsaw (Poland); Institute of Optoelectronics, Military University of Technology, Kaliskiego 2, 00-908 Warsaw (Poland)

    2015-01-07

    In this work, the results of contactless magnetoconductance and Raman spectroscopy measurements performed for a graphene sample after its immersion in NaCl solution were presented. The properties of the immersed sample were compared with those of a non-immersed reference sample. Atomic force microscopy and electron spin resonance experiments confirmed the deposition of NaCl nanoparticles on the graphene surface. A weak localization signal observed using contactless magnetoconductance showed the reduction of the coherence length after NaCl treatment of graphene. Temperature dependence of the coherence length indicated a change from ballistic to diffusive regime in electron transport after NaCl treatment. The main inelastic scattering process was of the electron-electron type but the major reason for the reduction of the coherence length at low temperatures was additional, temperature independent, inelastic scattering. We associate it with spin flip scattering, caused by NaCl nanoparticles present on the graphene surface. Raman spectroscopy showed an increase in the D and D′ bands intensities for graphene after its immersion in NaCl solution. An analysis of the D, D′, and G bands intensities proved that this additional scattering is related to the decoration of vacancies and grain boundaries with NaCl nanoparticles, as well as generation of new on-site defects as a result of the decoration of the graphene surface with NaCl nanoparticles. The observed energy shifts of 2D and G bands indicated that NaCl deposition on the graphene surface did not change carrier concentration, but reduced compressive biaxial strain in the graphene layer.

  7. Electron scattering in graphene with adsorbed NaCl nanoparticles

    International Nuclear Information System (INIS)

    Drabińska, Aneta; Kaźmierczak, Piotr; Bożek, Rafał; Karpierz, Ewelina; Wysmołek, Andrzej; Kamińska, Maria; Wołoś, Agnieszka; Pasternak, Iwona; Strupiński, Włodek; Krajewska, Aleksandra

    2015-01-01

    In this work, the results of contactless magnetoconductance and Raman spectroscopy measurements performed for a graphene sample after its immersion in NaCl solution were presented. The properties of the immersed sample were compared with those of a non-immersed reference sample. Atomic force microscopy and electron spin resonance experiments confirmed the deposition of NaCl nanoparticles on the graphene surface. A weak localization signal observed using contactless magnetoconductance showed the reduction of the coherence length after NaCl treatment of graphene. Temperature dependence of the coherence length indicated a change from ballistic to diffusive regime in electron transport after NaCl treatment. The main inelastic scattering process was of the electron-electron type but the major reason for the reduction of the coherence length at low temperatures was additional, temperature independent, inelastic scattering. We associate it with spin flip scattering, caused by NaCl nanoparticles present on the graphene surface. Raman spectroscopy showed an increase in the D and D′ bands intensities for graphene after its immersion in NaCl solution. An analysis of the D, D′, and G bands intensities proved that this additional scattering is related to the decoration of vacancies and grain boundaries with NaCl nanoparticles, as well as generation of new on-site defects as a result of the decoration of the graphene surface with NaCl nanoparticles. The observed energy shifts of 2D and G bands indicated that NaCl deposition on the graphene surface did not change carrier concentration, but reduced compressive biaxial strain in the graphene layer

  8. Effect of chloride substitution on the order–disorder transition in NaBH4 and Na11BD4

    International Nuclear Information System (INIS)

    Olsen, Jørn Eirik; Karen, Pavel; Sørby, Magnus H.; Hauback, Bjørn C.

    2014-01-01

    Graphical abstract: Interactions that order the BD 4 - tetrahedra below the order–disorder transition became increasingly frustrated by the solute in the Na( 11 BD 4 ) 1−x Cl x solid solutions, and the order disappears at x = 0.158. Highlights: • The order–disorder transition temperature for Na(BH 4 ) 1−x Cl x and Na( 11 BD 4 ) 1−x Cl x is highly dependent on the Cl-content, x. • The transition is characterized by DSC for Na( 11 BD 4 ) 1−x Cl x for x = 0, 0.10 and 0.15. • No transition is observed for x ⩾ 0.20 on cooling to 8 K. • The crystal structures are reported for Na 11 BD 4 at room temperature and 8 K and Na( 11 BD 4 ) 1−x Cl x (x = 0.10, 0.15, 0.20 and 0.25) at 8 K from powder neutron diffraction. -- Abstract: Phase transition associated with anion disordering over two orientations in Na 11 BD 4 (NaBH 4 ) and its solid solutions with NaCl, Na( 11 BD 4 ) 1−x Cl x , is investigated with powder diffraction (neutron and synchrotron radiation), differential scanning calorimetry and Raman spectroscopy. Upon heating, the transition temperature extrapolated to zero rate of heating is 192.2 K for Na 11 BD 4 , ΔS = 4.41 J/mol K, hysteresis 1.7 K and the volume increase 0.43%. Thermal parameters of the transition in Na( 11 BD 4 ) 1−x Cl x follow a colligative-property model of an ideal solution, with x = 0.158(1) as the critical concentration at which the ordering interactions and the transition itself are eliminated. On approaching this limit, the tetragonal distortion of the ordered structure decreases somewhat towards the cubic average, and this is associated with a partial disorder of the tetrahedral anions seen by diffraction methods. In fact, a 3% disorder is already present in the pure solvent of the solid solution (Na 11 BD 4 ) at 8 K

  9. Na+/H+ and Na+/NH4+ exchange activities of zebrafish NHE3b expressed in Xenopus oocytes

    Science.gov (United States)

    Ito, Yusuke; Kato, Akira; Hirata, Taku; Hirose, Shigehisa

    2014-01-01

    Zebrafish Na+/H+ exchanger 3b (zNHE3b) is highly expressed in the apical membrane of ionocytes where Na+ is absorbed from ion-poor fresh water against a concentration gradient. Much in vivo data indicated that zNHE3b is involved in Na+ absorption but not leakage. However, zNHE3b-mediated Na+ absorption has not been thermodynamically explained, and zNHE3b activity has not been measured. To address this issue, we overexpressed zNHE3b in Xenopus oocytes and characterized its activity by electrophysiology. Exposure of zNHE3b oocytes to Na+-free media resulted in significant decrease in intracellular pH (pHi) and intracellular Na+ activity (aNai). aNai increased significantly when the cytoplasm was acidified by media containing CO2-HCO3− or butyrate. Activity of zNHE3b was inhibited by amiloride or 5-ethylisopropyl amiloride (EIPA). Although the activity was accompanied by a large hyperpolarization of ∼50 mV, voltage-clamp experiments showed that Na+/H+ exchange activity of zNHE3b is electroneutral. Exposure of zNHE3b oocytes to medium containing NH3/NH4+ resulted in significant decreases in pHi and aNai and significant increase in intracellular NH4+ activity, indicating that zNHE3b mediates the Na+/NH4+ exchange. In low-Na+ (0.5 mM) media, zNHE3b oocytes maintained aNai of 1.3 mM, and Na+-influx was observed when pHi was decreased by media containing CO2-HCO3− or butyrate. These results provide thermodynamic evidence that zNHE3b mediates Na+ absorption from ion-poor fresh water by its Na+/H+ and Na+/NH4+ exchange activities. PMID:24401990

  10. Vojnici, odlikovanja i vojno znakovlje na nadgrobnim spomenicima iz Viminacija

    OpenAIRE

    Milovanović, Bebina

    2014-01-01

    Vojnici, odlikovanja i vojna obilježja na nadgrobnim spomenicima iz Viminacija poznati su sa osam stela i jednog sarkofaga. Cijela figura vojnika prikazana na jednoj steli predstavlja osobu višeg ranga. Iz natpisa saznajemo da je spomenik napravljen u čast Gaja Kornelija Rufa, dekuriona (vijećnik) i augura (svećenik koji je imao zadatak protumačiti volju bogova promatrajući let i ponašanje ptica) iz Viminacija.Vojnik prikazan na sarkofagu je nižeg ranga. Vojna odlikovanja su prikazana u oblik...

  11. VPLIV OPTIMIZACIJE NABAVNEGA PROCESA NA USPEŠNOST NABAVNEGA MANAGEMENTA

    OpenAIRE

    Štraus, Nataša

    2015-01-01

    Vloga nabavne funkcije se je od njenih začetkov pa do danes močno spremenila. V današnjem poslovnem okolju nabava ni več le podporna funkcija, ampak ima pomembno strateško vlogo v podjetju. Odgovorna je za nemoteno oskrbo materialov in storitev, upravljanje zalog, odnose z dobavitelji, za etično in družbeno odgovorno ravnanje podjetja. Tesno je povezana z logistiko in njenimi strategijami. Pomembno vpliva na stroške vhodnih materialov, na konkurenčnost podjetja in posledično tudi na dobiček ...

  12. O outro na relação

    Directory of Open Access Journals (Sweden)

    Reinoldo Marquezan

    2012-03-01

    Full Text Available O texto aborda as contribuições de Meirieu em relação ao outro que se estabelece na relação pedagógica e de Maturana que refere o outro como legítimo outro da convivência. Aponta ser necessário estabelecer o outro na relação como legítimo outro para a consecução do ato pedagógica.Palavras-chave: O Outro na Relação. Relação Pedagógica.

  13. Negativen vpliv konkurence na dejavnost zasebnega varovanja v Republiki Sloveniji

    OpenAIRE

    Kolar, Mojca

    2018-01-01

    Po osamosvojitvi Slovenije se je na slovenskem trgu začela intenzivno razvijati tudi dejavnost zasebnega varovanja in število varnostnih služb je začelo strmo naraščati. Močna konkurenca med njimi je z leti prinesla v dejavnost varovanja veliko negativnih posledic. Ena izmed teh so tudi plače varnostnega osebja, ki so danes daleč pod slovenskim povprečjem. Toda za sistemom plač zaposlenih stoji plačni sistem storitev na trgu varovanja. Magistrska naloga obravnava problematiko neobičajno ...

  14. SPLETNA APLIKACIJA ZA PREVERJANJE NASTAVITEV ZASEBNOSTI NA FACEBOOKU

    OpenAIRE

    Žolek, Matija

    2013-01-01

    Diplomsko delo obravnava problem zasebnosti na spletnem družbenem omrežju Facebook. Pravice do zasebnosti so vse bolj izpostavljene okolju, v katerem se nahajamo. Prav zaradi spletnih družbenih omrežij, kot je npr. Facebook, postaja vprašanje nadzora nad našo zasebnostjo in uporabo naših zasebnih podatkov tako zelo aktualna tematika. Facebook, kot vodilni med spletnimi družbenimi omrežji (Mba, 2013), vzbuja veliko vprašanj glede varnosti osebnih podatkov uporabnika. Naredili smo aplikacijo za...

  15. Razumevanje trojne narave kemijske vezi na submikroskopski ravni

    OpenAIRE

    Klun, Tina

    2017-01-01

    Magistrsko delo celostno obravnava trojno naravo pojma kemijska vez s poudarkom na submikroskopski ravni. S pojmom kemijska vez se učenci v Sloveniji srečajo v osmem razredu osnovne šole v tematskem sklopu povezovanje delcev/gradnikov. Zaradi abstraktnosti pojma kemijska vez je pomembno, da se pri učencih spodbuja učenje na makroskopski, submikroskopski in simbolni ravni, saj je tak način dela ključnega pomena za oblikovanje ustreznega mentalnega modela o kemijski vezi pri učencih. Pri gradnj...

  16. Utjecaj visokog hidrostatskog tlaka na kemijski sastav vina

    OpenAIRE

    Gelo, Klara

    2017-01-01

    U ovom radu ispitivan je utjecaj obrade visokim hidrostatskim tlakom na kemijski sastav crnog i bijelog vina. Određivani parametri su količina ukupnih polifenola, antocijana, tanina, boje, sumpora te kisika. Uzorci bijelog i crnog vina tretirani su visokim hidrostatskim tlakom od 200, 400 i 600 MPa u trajanju od 5, 15 i 25 minuta. Ispitivanjem utjecaja visokog hidrostatskog tlaka na kemijski sastav crnog i bijelog vina utvrđeno je da nema značajnije promjene u navedenim svojstvima. Na temelju...

  17. Personalidades vocacionais e processos de carreira na vida adulta

    OpenAIRE

    Magalhães, Mauro de Oliveira; Gomes, William B.

    2007-01-01

    Esta pesquisa abordou a relação entre interesses vocacionais e os processos de comprometimento e entrincheiramento na carreira em diferentes fases da vida. Uma amostra de 733 profissionais (415 homens e 318 mulheres) respondeu a medidas de comprometimento e de entrincheiramento na carreira. Os sujeitos foram categorizados de acordo com o interesse vocacional predominante na tipologia de Holland. As análises revelaram interação entre estágio de vida e personalidade vocacional para os escores d...

  18. ANALIZA UPORABNIŠKIH VMESNIKOV NA MOBILNIH NAPRAVAH

    OpenAIRE

    Bohak, Gregor

    2012-01-01

    V diplomskem delu smo predstavili pravila in smernice oblikovanja uporabniških vmesnikov na mobilnih napravah. Omejili smo se na platforme Google Android, Nokia Symbian, Nokia MeeGo, Apple iOS ter Microsoft Windows Phone 7. Za vsako izmed platform smo predstavili splošen model uporabniškega vmesnika, splošen model uporabniškega vmesnika aplikacije, navigacijske vzorce ter gradnike. Vse skupaj tudi smo obogatili z veliko grafičnega materiala. V drugem delu smo na podlagi pridobljenega znanja p...

  19. Direct extraction of a Na- beam from a sodium plasma

    International Nuclear Information System (INIS)

    Sasao, Namiko; Fujita, Junji; Yamaoka, Hitoshi; Wada, Motoi.

    1990-07-01

    Negative sodium ions (Na - ) were extracted from a small multi-cusp ion source. A steady state sodium plasma was produced by primary electrons in a sodium gas evaporating from a metal sample placed in the discharge chamber. The Na - current density of 1.5 μA/cm 2 was obtained from a single aperture of 1.5 mm diameter at relatively low discharge power of about 0.4 W and filament power of 50 W. Extraction characteristics were studied by changing the plasma electrode bias. The extracted Na - current showed dependence on the bias voltage similar to that of H - or Li - volume production. (author)

  20. Polimorfismo na produção de medicamentos

    Directory of Open Access Journals (Sweden)

    Gabriel Lima Barros de Araujo

    2012-01-01

    Full Text Available O polimorfismo pode ocasionar desvios de qualidade durante o processo produtivo e influenciar o desempenho dos medicamentos. Por isso, o entendimento do fenômeno e suas implicações abre um campo amplo de possibilidades a serem exploradas na área farmacêutica, incluindo o surgimento de novos paradigmas e ferramentas na garantia da qualidade de medicamentos. Este trabalho apresenta uma introdução aos aspectos básicos do fenômeno do polimorfismo e suas implicações na produção e controle de medicamentos, com ênfase no polimorfismo dos fármacos.

  1. VPLIV VAN DER WAALSOVIH SIL NA TVORBO ASOCIIRANIH MOLEKUL

    OpenAIRE

    Kuster, Bernarda

    2014-01-01

    Namen diplomske naloge je preučiti vpliv van der Waalsovih sil na tvorbo asociiranih molekul. V ta namen smo izbrali površinsko aktivne snovi, ki imajo amfifilne lastnosti in vplivajo na povšinske in medfazne napetosti ter pri določeni koncentraciji, imenovani kritična micelna koncentracija (CMC), tvorijo molekulske skupke, ki jim pravimo micele. Kritično micelno koncentracijo smo določili trem površinsko aktivnim snovem: heksadeciltrimetilamonijevemu bromidu, tetradeciltrimetilamonijevemu b...

  2. Técnica intramuscular na gluteoplastia de aumento

    OpenAIRE

    Carvalho, Francisco de Assis Montenegro Cido; Alcântara, Fernando Soares de; Martins, Elmiro Heli; Kruse, Ricardo Lapa; Nogueira, Régis Pinheiro; Raad, Nidall de Sousa

    2012-01-01

    INTRODUÇÃO: Região glútea harmoniosa é considerada elemento essencial na composição da beleza corporal e expressão maior de feminilidade, suscitando o crescente interesse de homens e mulheres na melhoria estética dessa região. O objetivo deste estudo é demonstrar uma alternativa às técnicas já publicadas acerca da gluteoplastia de aumento, baseada na colocação da prótese intramuscular, utilizando de forma simplificada os limites da dissecção, tendo como referência as estruturas anatômicas fix...

  3. Fluorine-18 NaF PET imaging of child abuse

    Energy Technology Data Exchange (ETDEWEB)

    Drubach, Laura A. [Children' s Hospital Boston and Harvard Medical School, Department of Radiology, Division of Nuclear Medicine/PET, Boston, MA (United States); Sapp, Mark.V. [School of Osteopathic Medicine, Child Abuse Research Education and Services (CARES) Institute University of Medicine and Dentistry of New Jersey, New Jersey (United States); Laffin, Stephen [Children' s Hospital Boston, Department of Radiology, Division of Nuclear Medicine/PET, Boston, MA (United States); Kleinman, Paul K. [Children' s Hospital Boston and Harvard Medical School, Department of Radiology, Division of Musculoskeletal Imaging, Boston, MA (United States)

    2008-07-15

    We describe the use of {sup 18}F-NaF positron emission tomography (PET) whole-body imaging for the evaluation of skeletal trauma in a case of suspected child abuse. To our knowledge, 18F NaF PET has not been used in the past for the evaluation of child abuse. In our patient, this technique detected all sites of trauma shown by initial and follow-up skeletal surveys, including bilateral metaphyseal fractures of the proximal humeri. Fluorine-18 NaF PET has potential advantage over Tc-99m-labeled methylene diphosphonate (MDP) based upon superior image contrast and spatial resolution. (orig.)

  4. Fluorine-18 NaF PET imaging of child abuse

    International Nuclear Information System (INIS)

    Drubach, Laura A.; Sapp, Mark V.; Laffin, Stephen; Kleinman, Paul K.

    2008-01-01

    We describe the use of 18 F-NaF positron emission tomography (PET) whole-body imaging for the evaluation of skeletal trauma in a case of suspected child abuse. To our knowledge, 18F NaF PET has not been used in the past for the evaluation of child abuse. In our patient, this technique detected all sites of trauma shown by initial and follow-up skeletal surveys, including bilateral metaphyseal fractures of the proximal humeri. Fluorine-18 NaF PET has potential advantage over Tc-99m-labeled methylene diphosphonate (MDP) based upon superior image contrast and spatial resolution. (orig.)

  5. Epidemiologia da raiva humana na Guanabara

    Directory of Open Access Journals (Sweden)

    Alfredo R. Matta B. da Silva

    1971-08-01

    Full Text Available A raiva humana se mantém como problema de Saúde Pública, especialmente nas áreas urbanas, onde o cão atua como principal reservatório e fonte imediata de infecção. A deficiência de programas de controle de cães vadios, de imunização sistemática e de educação sanitária, contribui para a perpetuação da cadeia epidemiológioa. O presente estudo analisa todos os casos de raiva humana, observados em habitantes do Estado da Guanabara, no período 1965-1969, segundo as variáveis: idade, sexo, côr, variação estacional, período de incubação e de duração da fase clínica, fonte de infecção, local de mordedura e uso de vacina posterior à exposição. Os principais resultados foram: 1. A ravia na Guanabara, parece ser mais comum nos grupos etários mais jovens e nos homens. 2. Não se observou variação estacional. 3. O período de incubação mediano foi de 45 dias e de duração da fase clínica de 3 dias. 4. Ocorreu uma associação entre período de incubação menor e vacinação incompleta.

  6. Cidade-ciborgue: a cidade na cibercultura

    Directory of Open Access Journals (Sweden)

    André Lemos

    2008-11-01

    Full Text Available As cidades contemporâneas passam por transfigurações importantes com o advento das novas tecnologias da comunicação e informação e, embora toda cidade seja um artefato complexo composto por diversas redes materiais e espirituais (Saint Simon, podemos ver as atuais cidades como uma cidade-ciborgue. O objetivo deste artigo é descrever e analisar as principais transformações pelas quais passa o espaço urbano na atual cibercultura. Torna-se urgente compreender as transformações da cidade contemporânea em meio às novas tecnologias de base micro-eletrônica e de telecomunicações. Pretendemos aqui abordar a questão das cidades da cibercultura sob o prisma do que chamaremos "cidade-ciborgue". Palavras-chave cibercultura, cibercidade, cidade, comunicação Abstract Cities have been through major transformations due to information and communication technologies. Although every city is a complex artifact made of several material and spiritual networks (Saint Simon, we can view our modern cities as cyborg-cities. The aim of this paper is to describe and analyze some major changes in the urban space in terms of cyberculture. There is a need to understand the transformations of the contemporary city in face of the new technologies of telecommunications and microelectronics. We intend to approach the subject of cities and cyberculture from the point of view of what we are calling "the cyborg-city". Key words cyberculture, cybercity, city, communication

  7. A publicidade na perspectiva de Baudrillard

    Directory of Open Access Journals (Sweden)

    Maria Ogécia Drigo

    2009-09-01

    Full Text Available Resumo O propósito deste artigo é apresentar as idéias de Baudrillard sobre publicidade, tratadas na obra O sistema dos objetos. Assim, discutem-se os conceitos de arranjo e de ambiência que culminam no conceito de funcionalidade, os quais permitem apresentar as relações que se estabelecem entre os seres humanos, e entre eles e os objetos. Em seguida, aborda-se o papel da publicidade em meio a esses objetos/signos. Palavras-chave: Jean Baudrillard; comunicação; publicidade; funcionalidade; objetos/signos. Resumen El propósito de este artículo es presentar las ideas de Baudrillard sobre la publicidad, que constan en la obra El sistema de los objetos. Se discuten los conceptos de arreglo y de ambiencia que culminan en el concepto de funcionalidad, los cuales permiten presentar las relaciones que se establecen entre los seres humanos y entre ellos y los objetos. En seguida,se aborda el papel de la publicidad en medio de esos objetos/signos. Palabras-clave: Jean Baudrillard; comunicación; publicidad; funcionalidad; objetos/signos. Abstract This article intends to present Baudrillard’s ideas about advertising as considered in “Le système des objects”, his first book. The concepts of settlement, ambience and functionality are discussed. They make it possible to present the relations constructed among human beings and among humans and objects. We then discuss the role of advertising amongst these objects/signs. Keywords: Jean Baudrillard; communication; advertising; functionality; objects/signs.

  8. PRAVO NA PRISTUP SUDU EUROPSKE UNIJE

    Directory of Open Access Journals (Sweden)

    Katarina Knol Radoja

    2016-01-01

    Full Text Available Restriktivni pristup tumačenja pretpostavki dopuštenosti podnošenja tužbe za poništenje pred Sudom Europske unije kada su u pitanju fizičke i pravne osobe prije donošenja Lisabonskog ugovora bio je predmetom niza doktrinarnih kri- tika. Cilj je ovog rada analizirati praktični utjecaj novih pravila o dopuštenosti podnošenja tužbe u svjetlu interpretativnih rješenja koje je dao Sud. Konkret- no, analizirat će se imaju li temeljem novog članka 263. stavka 4. Ugovora o funkcioniranju Europske unije privatni podnositelji jednostavniji pristup Sudu Europske unije u usporedbi s onim prije izmjena iz Lisabonskog ugovora. Osim toga, analizirat će se i kompatibilnost navedenog članka s međunarodnim ob- vezama koje proizlaze iz Aarhuške konvencije o pristupu informacijama, sud- jelovanju javnosti u odlučivanju i pristupu pravosuđu u pitanjima okoliša, spo- razuma kojeg je i Europska unija stranka. Na kraju rada, dolazi se do zaključka da, unatoč postojanju određenog napret- ka u smislu olakšavanja fizičkim i pravnim osobama pristup sudu, tim će oso- bama izravni pristup, radi osporavanja nezakonitosti akata tijela i institucija Europske unije i dalje biti dostupan samo u ograničenim slučajevima.

  9. O Perfume ou o Ignorado na Cultura

    Directory of Open Access Journals (Sweden)

    Márcio Boaventura Jr.

    2011-05-01

    Full Text Available

    Resumo: A proposta do artigo é analisar o filme “Perfume, a história de um assassino” de Tom Tykwer sob o ponto de vista da psicanálise e da educação. Para tanto, buscamos debater o mal-estar na cultura, especialmente suas manifestações nas salas de aula, a partir dos diversos pontos do enredo em que podemos ilustrar o que Freud argumentou em sua tese sobre o tema.

     

    Resume: This article is intended to analyze Tom Tykwer's film Perfume: The Story of a Mur-derer (2006 under an educational and psychoanalytical perspective. Therefore we try to question cultural discontentment, mostly its manifestations in class, depicting the plot's many points of view to illustrate Freud thesis' arguing on the subject.

     

  10. Borehole sealing with highly compactd Na bentonite

    International Nuclear Information System (INIS)

    Pusch, R.

    1981-12-01

    This report describes the use of highly compacted Na bentonite for borehole plugging. Bentonites have an extremely low permeability and a low diffusivity, and a swelling ability which produces a nonleaching boundary between clay and rock if the initial bulk density of the bentonite is sufficiently high. The suggested technique, which is applicable to long vertical, and inclined, as well as horizontal boreholes, is based on the use of perforated copper pipes to insert elements of compacted bentonite. Such pipe segments are connected at the rock surface and successively inserted in the hole. When the hole is equipped, the clay takes up water spontaneously and swells through the perforation, and ultimately forms an almost completely homogenous clay core. It embeds the pipe which is left in the hole. Several tests were conducted in the laboratory and one field test was run in Stripa. They all showed that a gel soon fills the slot between the pipe and the confinement which had the form of metal pipes in the laboratory investigations. Subsequently, more clay migrates through the perforation and produces a stiff clay filling in the slot. The redistribution of minerals, leading ultimately to a high degree of homogeneity, can be described as a diffusion process. The rate of redistribution depends on the joint geometry and water flow pattern in the rock. In the rock with an average joint frequence of one per meter or higher, very good homogeneity and sealing ability of the clay are expected within a few months after the application of the plug. (author)

  11. Influência do tipo de farinha de trigo na elaboração de bolo tipo inglês Influence of the type of wheat flour in the elaboration of english-type cake

    Directory of Open Access Journals (Sweden)

    Luiz Carlos Gutkoski

    2011-12-01

    Full Text Available A farinha de trigo destinada à produção de bolo deve apresentar baixo teor protéico, massa extensível e baixa força geral de glúten. A pesquisa objetivou avaliar a influência do tipo de farinha de trigo na elaboração de bolo tipo inglês empregando a metodologia padrão de teste laboratorial proposta pela AACC. As amostras de farinha de trigo foram coletadas aleatoriamente em moinhos de trigo da região e os demais ingredientes adquiridos no comércio local. As farinhas de trigo foram caracterizadas quanto ao teor de proteína bruta, amido danificado, alveografia e farinografia. A repetibilidade e a reprodutibilidade da metodologia foi avaliada empregando uma das farinhas. Os bolos tipo inglês foram produzidos pela mistura dos ingredientes: farinha de trigo, açúcar refinado, margarina, leite em pó, ovo desidratado, sal, fermento químico e água em condições laboratorial pré-definidas. Os bolos foram avaliados quanto ao volume específico, atividade de água, características internas, porosidade, cor da crosta e cor do miolo. Os resultados foram submetidos à análise de variância e as diferenças entre as médias comparadas entre si pelo teste de Tukey a 5% de significância. A amostra de farinha de trigo com 68 x 10-4 J se mostrou mais adequada para elaboração de bolo tipo inglês, apresentando maior volume específico e maior escore de pontos, avaliado através das características sensoriais.Wheat flours for cake production must show features such as low protein content, dough extensibility and low gluten strength. The aim of this research was to evaluate the influence of the type of wheat flour in the elaboration of English-type cake using the standard method for laboratory testing proposed by AACC. The wheat flour samples were collected at random from wheat mills in the region, and the other ingredients were obtained at the local market. The wheat flours were characterized according to their crude protein content

  12. Relatório do estágio curricular supervisionado na Educação Infantil I: Centro Municipal de Educação Infantil Monteiro Lobato

    Directory of Open Access Journals (Sweden)

    Eva Aparecida dos Santos Ribeiro

    2011-12-01

    Full Text Available Este presente artigo é um relato de observação e regência na Educação Infantil, realizado no Centro Municipal de Educação Infantil Monteiro Lobato, localizado na Avenida dos jacarandás s/n, no Jardim das Primaveras, Sinop-MT. As observações e as regências foram realizadas no período vespertino, entre os dias 14 de junho à 05 de julho do ano de 2011, totalizando 60 horas de Estágio. Dias antes de iniciar o trabalho no CMEI, foi realizada uma visita para conhecer o ambiente onde iria fazer o estágio, uma breve observação da sala, conhecer a professora regente, conhecer o PPP do CMEI e sua metodologia de trabalho, como são realizados os planejamentos e a realizações dos projetos para melhor desenvolvimento das atividades a ser trabalhadas durante o estágio. A professora regente da turma está desenvolvendo o projeto sobre o Meio Ambiente, Preservação e reciclagem e seres vivos e não vivos, nos passando seu caderno de planejamento para conseguimos dar procedimento no seu trabalho, sempre estando presentes no caso de dúvidas e de ideias para desenvolver as atividades. No primeiro dia, fui apresentada eu aos alunos, e foi proposta uma roda de conversa para a apresentação dos alunos, para conhecê-los melhor, com todos sentados no chão e além de falarem o seu nome, falar se tinham irmãos, com quem morram?, e se gostam da escola e dos amigos ?, incluindo a professora regente da turma, me deixando aberta para suas perguntas e curiosidades, agindo sempre de modo amigável, para que os alunos não achassem que eu estava invadindo o seu espaço, a roda de conversa foi muito agradável. Nos próximos dias de atividades com o planejamento diário sempre de acordo com as necessidades dos alunos. Os alunos se demonstraram entusiasmados e aprenderam muito com as atividades lúdicas, leituras e dinâmicas. O conhecimento adquirido durante o estágio de Educação Infantil foi da importância de ensinar e também aprender, sempre

  13. Active ion transport in the renal proximal tubule. II. Ionic dependence of the Na pump

    OpenAIRE

    1984-01-01

    The dependence of Na pump activity on intracellular and extracellular Na+ and K+ was investigated using a suspension of rabbit cortical tubules that contained mostly (86%) proximal tubules. The ouabain- sensitive rate of respiration (QO2) was used to measure the Na pump activity of intact tubules, and the Na,K-ATPase hydrolytic activity was measured using lysed proximal tubule membranes. The dependence (K0.5) of the Na pump on intracellular Na+ was affected by the relative intracellular conce...

  14. High-Performance Na-O2 Batteries Enabled by Oriented NaO2 Nanowires as Discharge Products.

    Science.gov (United States)

    Khajehbashi, S Mohammad B; Xu, Lin; Zhang, Guobin; Tan, Shuangshuang; Zhao, Yan; Wang, Lai-Sen; Li, Jiantao; Luo, Wen; Peng, Dong-Liang; Mai, Liqiang

    2018-06-13

    Na-O 2 batteries are emerging rechargeable batteries due to their high theoretical energy density and abundant resources, but they suffer from sluggish kinetics due to the formation of large-size discharge products with cubic or irregular particle shapes. Here, we report the unique growth of discharge products of NaO 2 nanowires inside Na-O 2 batteries that significantly boosts the performance of Na-O 2 batteries. For this purpose, a high-spin Co 3 O 4 electrocatalyst was synthesized via the high-temperature oxidation of pure cobalt nanoparticles in an external magnetic field. The discharge products of NaO 2 nanowires are 10-20 nm in diameter and ∼10 μm in length, characteristics that provide facile pathways for electron and ion transfer. With these nanowires, Na-O 2 batteries have surpassed 400 cycles with a fixed capacity of 1000 mA h g -1 , an ultra-low over-potential of ∼60 mV during charging, and near-zero over-potential during discharging. This strategy not only provides a unique way to control the morphology of discharge products to achieve high-performance Na-O 2 batteries but also opens up the opportunity to explore growing nanowires in novel conditions.

  15. Characteristics of the Na/beta-alumina/Na cell as a sodium vapor pressure sensor

    International Nuclear Information System (INIS)

    Takikawa, O.; Imai, A.; Harata, M.

    1982-01-01

    The EMF and voltage-current characteristics for a galvanic cell with the configuration Na vapor (P 1 )/sodium beta-alumina/Na vapor (P 2 ) were studied. It was verified that the EMF followed the Nernst relation over a wide pressure range. For example, when P 1 = 2 x 10 -2 mm Hg and beta-alumina temperature = 340 0 C, the measured EMF agreed with the calculated value in P 2 range from 10 -5 to 10 -2 mm Hg. At lower pressure range, the measured EMF showed a negative deviation. Coexisting argon gas did not influence the cell EMF characteristic. In an atmosphere containing oxygen, the measured EMF was very high at first. Then it decreased and finally approached a value which agreed with the Nernst equation after several hours. At low beta-alumina temperatures, current saturation was observed in the voltage versus current relation with the anode on the P 2 side. Although the sodium pressure could be determined from saturating current measurement, the measurable pressure range was narrower than that for EMF measurement. At high beta-alumina temperature, current saturation was not clear. Values of 6 x 10 -6 (Ω cm) -1 for the electron conductivity and 6 x 10 -10 (Ω cm) -1 for the hole conductivity at 340 0 C were obtained for beta-alumina from the voltage-current characteristics at low sodium pressure. (Auth.)

  16. α-synuclein assemblies sequester neuronal α3-Na+/K+-ATPase and impair Na+ gradient

    Science.gov (United States)

    Shrivastava, Amulya Nidhi; Redeker, Virginie; Fritz, Nicolas; Pieri, Laura; Almeida, Leandro G; Spolidoro, Maria; Liebmann, Thomas; Bousset, Luc; Renner, Marianne; Léna, Clément; Aperia, Anita; Melki, Ronald; Triller, Antoine

    2015-01-01

    Extracellular α-synuclein (α-syn) assemblies can be up-taken by neurons; however, their interaction with the plasma membrane and proteins has not been studied specifically. Here we demonstrate that α-syn assemblies form clusters within the plasma membrane of neurons. Using a proteomic-based approach, we identify the α3-subunit of Na+/K+-ATPase (NKA) as a cell surface partner of α-syn assemblies. The interaction strength depended on the state of α-syn, fibrils being the strongest, oligomers weak, and monomers none. Mutations within the neuron-specific α3-subunit are linked to rapid-onset dystonia Parkinsonism (RDP) and alternating hemiplegia of childhood (AHC). We show that freely diffusing α3-NKA are trapped within α-syn clusters resulting in α3-NKA redistribution and formation of larger nanoclusters. This creates regions within the plasma membrane with reduced local densities of α3-NKA, thereby decreasing the efficiency of Na+ extrusion following stimulus. Thus, interactions of α3-NKA with extracellular α-syn assemblies reduce its pumping activity as its mutations in RDP/AHC. PMID:26323479

  17. Identification of CW two-photon transitions in Na2 and NaK

    International Nuclear Information System (INIS)

    Morgan, G.P.

    1983-01-01

    This thesis reports on the two-photon visible excitation spectra of sodium and potassium vapors. In the past, similar work has been performed on sodium and many atomic two-photon transitions have been characterized. However, many extra signals exist which do not possess the ground, 3S, state hyperfine splitting. These extra transitions are due to the sodium dimer Na 2 . 79 such transitions, from 5800A - 6500A, which lie within the resolution of the apparatus have been studied. The molecules are excited with a lowpower narrow band counterpropagating cw dye laser beam and two-photon fluorescence. The fluorescence intensities of many of these transitions are greater than the 3S to 5S and 3S to 4D atomic signals, where the 3P enhancing state lies 300 cm -1 from resonance. By comparing the number density of the atomic with any molecular ground state and also the two-photon transition rates to excited states, the intermediate enhancing state for a two-photon transition in Na 2 can be predicted to be less than 1 cm -1 from resonance with the two-photon transition. This observation, along with published Dunham coefficients, is used to identify the states involved in the two-photon transitions

  18. FATORES DE RISCO NA REPETIÇÃO DE GRAVIDEZ NA ADOLESCÊNCIA

    Directory of Open Access Journals (Sweden)

    Eulália Maria Chaves-Maia

    2009-01-01

    Full Text Available A fim de traçar o perfil biopsicossocial de adolescentes com repetição de gravidez e seus fatores associados, investigou-se questões socio-demográficas, variáveis biológicas e psicológicas de 50 adolescentes multigestas.Os dados analisados através de estatística descritiva apontam que a maioria das adolescentes não frequentava a escola e vivia em união estável, que 54% não fez uso de métodos contraceptivos na primeira relação sexual e 88% nunca participou dos programas de Planejamento Familiar. Assim, políticas públicas de educação sexual e reprodutiva devem identificar comportamentos sexuais de risco, atuar na construção de valores familiares e no planejamento das gestações.

  19. TELEJORNALISMO NA ERA DIGITAL: ASPECTOS DA NARRATIVA TRANSMÍDIA NA TELEVISÃO DE PAPEL

    Directory of Open Access Journals (Sweden)

    Elaide Martins

    2012-12-01

    Full Text Available O presente artigo propõe uma reflexão sobre o jornalismo audiovisual a partir da perspectiva da narrativa transmídia (NT, termo cunhado por Henry Jenkins (2009 em suas pesquisas sobre a cultura da convergência. Como a convergência midiática vem afetando a linguagem e a estética do jornalismo audiovisual? E a rotina e perfil de seus profissionais?  E a relação com a audiência? Quais os novos paradigmas e o que mudou em seus processos produtivos com o uso das novas mídias? A fim de refletir sobre estas e outras questões, procuramos identificar e analisar aspectos da narrativa transmídia na TV Folha, um programa audiovisual inspirado no impresso, que nasceu como um canal privado na web e hoje é exibido por uma emissora pública. Um produto que nos leva a crer que a narrativa transmídia começa a firmar o seu espaço no jornalismo audiovisual brasileiro a partir da relação deste com as novas plataformas de informação.

  20. Quantification of ventricular unloading by 3D echocardiography in single ventricle of left ventricular morphology following superior cavo-pulmonary anastomosis and Fontan completion – a feasibility study

    Directory of Open Access Journals (Sweden)

    Deepa Sasikumar

    2017-01-01

    Conclusions: We provide preliminary information on 3DE volume data of single ventricle of LV morphology and the pattern of unloading after SCPA and Fontan operation. Immediate significant volume unloading occurred after SCPA which tended to catch-up after 3 months, whereas continued fall in ventricular volume with time was noted after Fontan.

  1. Characterization and antibacterial activity of silver exchanged regenerated NaY zeolite from surfactant-modified NaY zeolite.

    Science.gov (United States)

    Salim, Mashitah Mad; Malek, Nik Ahmad Nizam Nik

    2016-02-01

    The antibacterial activity of regenerated NaY zeolite (thermal treatment from cetyltrimethyl ammonium bromide (CTAB)-modified NaY zeolite and pretreatment with Na ions) loaded with silver ions were examined using the broth dilution minimum inhibitory concentration (MIC) method against Escherichia coli (E. coli ATCC 11229) and Staphylococcus aureus (S. aureus ATCC 6538). X-ray diffraction (XRD), attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy, field emission scanning electron microscopy (FESEM), energy dispersive X-ray (EDX) and chemical elemental analyses were used to characterize the regenerated NaY and AgY zeolites. The XRD patterns indicated that the calcination and addition of silver ions on regenerated NaY zeolite did not affect the structure of the regenerated NaY zeolite as the characteristic peaks of the NaY zeolite were retained, and no new peaks were observed. The regenerated AgY zeolite showed good antibacterial activity against both bacteria strains in distilled water, and the antibacterial activity of the samples increased with increasing Ag loaded on the regenerated AgY zeolite; the regenerated AgY zeolite was more effective against E. coli than S. aureus. However, the antibacterial activity of the regenerated AgY was not effective in saline solution for both bacteria. The study showed that CTAB-modified NaY zeolite materials could be regenerated to NaY zeolite using thermal treatment (550°C, 5h) and this material has excellent performance as an antibacterial agent after silver ions loading. Copyright © 2015 Elsevier B.V. All rights reserved.

  2. Distinct pH dependencies of Na+/K+ selectivity at the two faces of Na,K-ATPase.

    Science.gov (United States)

    Cornelius, Flemming; Tsunekawa, Naoki; Toyoshima, Chikashi

    2018-02-09

    The sodium pump (Na,K-ATPase) in animal cells is vital for actively maintaining ATP hydrolysis-powered Na + and K + electrochemical gradients across the cell membrane. These ion gradients drive co- and countertransport and are critical for establishing the membrane potential. It has been an enigma how Na,K-ATPase discriminates between Na + and K + , despite the pumped ion on each side being at a lower concentration than the other ion. Recent crystal structures of analogs of the intermediate conformations E2·Pi·2K + and Na + -bound E1∼P·ADP suggest that the dimensions of the respective binding sites in Na,K-ATPase are crucial in determining its selectivity. Here, we found that the selectivity at each membrane face is pH-dependent and that this dependence is unique for each face. Most notable was a strong increase in the specific affinity for K + at the extracellular face ( i.e. E2 conformation) as the pH is lowered from 7.5 to 5. We also observed a smaller increase in affinity for K + on the cytoplasmic side (E1 conformation), which reduced the selectivity for Na + Theoretical analysis of the p K a values of ion-coordinating acidic amino acid residues suggested that the face-specific pH dependences and Na + /K + selectivities may arise from the protonation or ionization of key residues. The increase in K + selectivity at low pH on the cytoplasmic face, for instance, appeared to be associated with Asp 808 protonation. We conclude that changes in the ionization state of coordinating residues in Na,K-ATPase could contribute to altering face-specific ion selectivity. © 2018 by The American Society for Biochemistry and Molecular Biology, Inc.

  3. Down-Regulation of the Na+-Coupled Phosphate Transporter NaPi-IIa by AMP-Activated Protein Kinase

    Directory of Open Access Journals (Sweden)

    Miribane Dërmaku-Sopjani

    2013-11-01

    Full Text Available Background/Aims: The Na+-coupled phosphate transporter NaPi-IIa is the main carrier accomplishing renal tubular phosphate reabsorption. It is driven by the electrochemical Na+ gradient across the apical cell membrane, which is maintained by Na+ extrusion across the basolateral cell membrane through the Na+/K+ ATPase. The operation of NaPi-IIa thus requires energy in order to avoid cellular Na+ accumulation and K+ loss with eventual decrease of cell membrane potential, Cl- entry and cell swelling. Upon energy depletion, early inhibition of Na+-coupled transport processes may delay cell swelling and thus foster cell survival. Energy depletion is sensed by the AMP-activated protein kinase (AMPK, a serine/threonine kinase stimulating several cellular mechanisms increasing energy production and limiting energy utilization. The present study explored whether AMPK influences the activity of NAPi-IIa. Methods: cRNA encoding NAPi-IIa was injected into Xenopus oocytes with or without additional expression of wild-type AMPK (AMPKα1-HA+AMPKβ1-Flag+AMPKγ1-HA, of inactive AMPKαK45R (AMPKα1K45R+AMPKβ1-Flag+AMPKγ1-HA or of constitutively active AMPKγR70Q (AMPKα1-HA+AMPKβ1-Flag+AMPKγ1R70Q. NaPi-IIa activity was estimated from phosphate-induced current in dual electrode voltage clamp experiments. Results: In NaPi-IIa-expressing, but not in water-injected Xenopus oocytes, the addition of phosphate (1 mM to the extracellular bath solution generated a current (Ip, which was significantly decreased by coexpression of wild-type AMPK and of AMPKγR70Q but not of AMPKαK45R. The phosphate-induced current in NaPi-IIa- and AMPK-expressing Xenopus ooocytes was significantly increased by AMPK inhibitor Compound C (20 µM. Kinetic analysis revealed that AMPK significantly decreased the maximal transport rate. Conclusion: The AMP-activated protein kinase AMPK is a powerful regulator of NaPi-IIa and thus of renal tubular phosphate transport.

  4. In vivo PTH provokes apical NHE3 and NaPi2 redistribution and Na-K-ATPase inhibition

    DEFF Research Database (Denmark)

    Zhang, Y; Norian, J M; Magyar, C E

    1999-01-01

    and to determine whether the same cellular signals drive the changes in apical and basolateral transporters. PTH-(1-34) (20 U), which couples to adenylate cyclase (AC), phospholipase C (PLC), and phospholipase A2 (PLA2), or [Nle8,18,Tyr34]PTH-(3-34) (10 U), which couples to PLC and PLA2 but not AC, were given....../diuresis and NHE3 and NaPi2 internalization, and that Na-K-ATPase inhibition is not secondary to depressed apical Na+ transport....

  5. Gravidez na adolescência: tendência na produção científica de enfermagem

    OpenAIRE

    Gurgel, Maria Glêdes Ibiapina; Alves, Maria Dalva Santos; Vieira, Neiva Francenely Cunha; Pinheiro, Patrícia Neyva da Costa; Barroso, Grasiela Teixeira

    2008-01-01

    A gravidez em adolescentes tem implicações biológica, psicológica, social, econômica e cultural. O estudo exploratório, descritivo e bibliográfico objetivou identificar as concepções da gravidez na adolescência, sujeito, vulnerabilidade e gênero, presentes na produção científica de Enfermagem. Foram selecionados intencionalmente quatro periódicos brasileiros e dois da América Latina indexados de 2002 a 2006 na Scientific Electronic Library. Dos 1.472 artigos identificados, 43 tinham como temá...

  6. Neutralization of Na2PO4: Reaction between Na3PO4 and CaCL2

    International Nuclear Information System (INIS)

    Xia Shenglan; Wang Luning

    1990-01-01

    The results of reaction Na 3 PO 4 with CaCl 2 in water at ambient and higher temperature are described. The reaction rate of Na 3 PO 4 with CaCl 2 is slow at ambient temperature and the reaction is complete at 260 deg C after 2 h. The products are Ca(OH) 2 and Ca 5 (PO 4 ) 3 (OH). The quantity of them is dependent upon the quanity of Na 3 PO 4 and CaCl 2 contained in water, all of them control pH of water

  7. 2018 NA62 Status Report to the CERN SPSC

    CERN Document Server

    NA62, Collaboration

    2018-01-01

    The status of the NA62 experiment is reported. The ongoing activities on detectors and hardware are summarised and the status of the data processing is reviewed. The result from the "K^{+}\\rightarrow\\pi^{+}\

  8. Na2MoO2As2O7

    Directory of Open Access Journals (Sweden)

    Raja Jouini

    2012-12-01

    Full Text Available Disodium molybdenum dioxide diarsenate, Na2MoO2As2O7, has been synthesized by a solid-state reaction. The structure is built up from MoAs2O12 linear units sharing corners to form a three-dimensional framework containing tunnels running along the a-axis direction in which the Na+ cations are located. In this framework, the AsV atoms are tetrahedrally coordinated and form an As2O7 group. The MoVI atom is displaced from the center of an octahedron of O atoms. Two Na+ cations are disordered about inversion centres. Structural relationships between different compounds: A2MoO2As2O7 (A = K, Rb, AMOP2O7 (A = Na, K, Rb; M = Mo, Nb and MoP2O7 are discussed.

  9. Fiebre del oro blanco: la cocaína

    Directory of Open Access Journals (Sweden)

    Iván Marín Argüello

    1999-12-01

    Full Text Available La planta de coca, Erythroxylon coca es cultivada en la zona occidental de América del Sur exigiendo condiciones de suelo muy particulares. La mezcla de las hojas de cocaína con sustancias químicas origina un polvo cristalino blanco, conocido comúnmente como cocaína. Al producto obtenido del tratamiento de la cocaína con solventes se le denomina crack. El consumo de cocaína, las formas de administración más diversas y el estado fisiológico logrado por los usuarios, es denominado flash 0 high Los efectos neuro-fisiológicos son muy variados, provocando sobre todo un fuerte estímulo al Sistema Nervioso Central (SNC, producto de la liberación de dopamina en las terminaciones nerviosas.

  10. Redetermination of Na(3)TaF(8).

    Science.gov (United States)

    Langer, Vratislav; Smrcok, Lubomír; Boca, Miroslav

    2010-09-01

    The crystal structure of trisodium octafluoridotantalate, Na(3)TaF(8), has been redetermined using diffractometer data collected at 153 K, resulting in more accurate bond distances and angles than obtained from a previous structure determination based on film data. The structure is built from layers running along [101], which are formed by distorted [TaF(8)] antiprisms and [NaF(6)] rectangular bipyramids sharing edges and corners. The individual layers are separated by eight-coordinated Na ions. Two atoms in the asymmetric unit are in special positions: the Ta atom is on a twofold axis in Wyckoff position 4e and one of the Na ions lies on an inversion centre in Wyckoff site 4d.

  11. Polishing large NaCl windows on a continuous polisher

    International Nuclear Information System (INIS)

    Williamson, R.

    1979-01-01

    The Helios and Antares CO 2 fusion laser systems incorporate numerous large sodium chloride windows. These must be refinished periodically, making necessary a consistent and predictable polishing capability. A continuous polisher (or annular lap) which might at Kirtland's Developmental Optical Facility. Large NaCl windows had not been polished on this type of machine. The machine has proven itself capable of producing lambda/16 figures at 633 nm (HeNe) with extremely smooth surfaces on glass. Since then, we have been working exclusively on NaCl optics. Due to different polishing parameters between NaCl and glass, and the slight solubility of the pitch in the slurry, this phase presents new problems. The work on glass will be reviewed. Results on NaCl to date will be reported. The potential of this type of machine relative to prisms, thin and irregularly shaped optics will be discussed

  12. Lattice sites of Na dopants in ZnO

    CERN Document Server

    AUTHOR|(CDS)2069243; Martins Correia, Joao; Amorim, Lígia; Decoster, Stefan; Ribeiro da Silva, Manuel; Da Costa Pereira, Lino Miguel

    2016-01-01

    The angular distribution of beta− particles emitted by the radioactive isotope 24Na was monitored following implantation into ZnO single crystals at fluences above 5E12 cm−2 at CERN’s ISOLDE facility. We identified sodium on two distinct sites: on substitutional Zn sites and on interstitial sites that are close to the so-called octahedral site. The interstitial Na was to large extent converted to substitutional Na already for annealing at 200°C, from which an activation energy of 0.8−1.3 eV, most likely around 1.2 eV, is estimated for the migration of interstitial Na in ZnO.

  13. NaKnowBase”: A Nanomaterials Relational Database

    Science.gov (United States)

    NaKnowBase is a relational database populated with data from peer-reviewed ORD nanomaterials research publications. The database focuses on papers describing the actions of nanomaterials in environmental or biological media including their interactions, transformations and poten...

  14. Effects of different NaCl Concentrations on germination and ...

    African Journals Online (AJOL)

    USER

    Salinity refers to the salt content of any given system. By nature, arid .... Effect of varying concentrations of NaCl on seed germination of Amaranthus hybridus in percentages. .... Osmotic differences could explain this phenomenon where by ...

  15. Hydrophilic C terminus of Salicornia europaea vacuolar Na /H ...

    Indian Academy of Sciences (India)

    2014-08-08

    Aug 8, 2014 ... Soil salinity caused, particularly by NaCl, is a major abi- otic stress worldwide. ... sodium, plants have developed several adaptive mechanisms including accumulation of ..... and pH-dependent manner. Proc. Natl. Acad. Sci.

  16. Na,K-pump modulates intercellular communication in vascular wall

    DEFF Research Database (Denmark)

    Matchkov, Vladimir

    were used as a model for electrical coupling of SMCs by measuring membrane capacitance (Cm). SMCs were uncoupled (evaluated by inhibition of vasomotion and desynchronization of calcium transients in vascular wall, or by reduction to half of Cm measured in paired A7r5 cells) when the Na......  Ouabain, a specific inhibitor of the Na,K-pump, has previously been shown to interfere with intercellular communication. Here we test the hypothesis that the communication between vascular smooth muscle cells (SMCs) is regulated through an interaction between the Na,K-pump and the Na......,Ca-exchanger leading to an increase in the intracellular calcium concentration in discrete areas near the plasma membrane. The intracellular calcium concentration in individual SMCs was imaged in cultured rat aortic SMCs (A7r5) and simultaneously with isometric force in rat mesenteric small arteries. Paired A7r5 cells...

  17. ser precoce na intervenção

    OpenAIRE

    Bernardo, Ana Carolina Couto

    2013-01-01

    Dissertação apresentada à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Ciências da Educação: Educação Especial, área de especialização em Domínio da Intervenção Precoce na Infância Este estudo centra-se na implementação de uma Escola de Mães, programa de educação parental realizado em seis sessões na freguesia de Calhetas, ilha de S. Miguel, e na avaliação comparativa, anterior e posterior ao programa, das três mães participantes no que...

  18. Agter elke man: Onderweg na inklusiewe taalgebruik in die ...

    African Journals Online (AJOL)

    31 Mei 2016 ... Agter elke man: Onderweg na inklusiewe taalgebruik in die Afrikaanse kerklied .... reaksie van gemeentelede en opmerkings op sosiale media ..... and unstable masculinity/ies of Jesus Christ and the multiple and changing ...

  19. NaKnowBase”: A Nanomaterials Relational Database

    Science.gov (United States)

    NaKnowBase is an internal relational database populated with data from peer-reviewed ORD nanomaterials research publications. The database focuses on papers describing the actions of nanomaterials in environmental or biological media including their interactions, transformations...

  20. VPLIV ELEKTRIČNIH VOZIL NA ZANESLJIVOST ELEKTROENERGETSKEGA SISTEMA

    OpenAIRE

    BOŽIČ, DUŠAN

    2017-01-01

    Zagotavljanje zanesljive oskrbe odjemalcev z električno energijo predstavlja primarno nalogo elektroenergetskih sistemov, na kar kaže tudi spreminjanje načina regulacije sistemskih operaterjev v dereguliranih trgih z električno energijo. Regulatorji pri regulaciji sistemskih operaterjev namreč vse pogosteje uvajajo regulacijo kakovosti dobave električne energije, ki v ospredje postavlja prav zanesljivost sistema. Prihodki sistemskih operaterjev so pri regulaciji kakovosti dobave električne en...